PCT Receiving Office Guidelines

Chapter IX: Nucleotide and/or Amino Acid Sequence Listing

Sequence Listing Furnished in ST.25 Text Format

223. The receiving Office examines whether the check list in Box No. IX of the request appropriately indicates the submission in electronic form (in ST.25 text format) of the sequence listing and checks that it was submitted by means accepted by the receiving Office. The receiving Office need not examine for compliance of the sequence listing furnished in ST.25 text format with the prescribed requirements set out in the standard contained in Annex C of the Administrative Instructions since that check is made by the International Searching Authority (Rule 13ter).

Sequence Listing Furnished in Page-Based Format (on Paper or as Image File(s))

224. The receiving Office examines whether the check list in Box No. IX of the request appropriately indicates “sequence listing part of the description” and checks whether the number of sheets of such sequence listing is indicated separately in the check list (Rule 3.3(a)(i)). If that number is not indicated separately, the receiving Office corrects the check list ex officio to indicate the appropriate number in items (b) and/or (f) as well as the total number of sheets (paragraphs 161 to 165) and invites the applicant to pay any required fee for sheets in excess of the previously calculated total number of sheets (paragraph 242). Form PCT/RO/102 or PCT/RO/133, as the case may be, is used for that purpose (paragraphs 252 to 265).

225. The receiving Office examines the sheets containing the sequence listing to a limited extent; it need not check the language of the sequence listing, compliance with requirements as to the presentation of the sequences, nor compliance with Rule 5.2. However, the receiving Office checks for compliance with the physical requirements necessary for the purpose of a reasonably uniform international publication as required by paragraph 3(i) of the said Annex C. Specifically, sheets of a sequence listing included in the international application must be presented as a separate part of the description (entitled “Sequence Listing”) and should be sequentially numbered in a series separate from that used in numbering the sheets of the request (first series), the sheets of the description, claims and abstract (second series), and any sheets of drawings (third series) (Section 207 and paragraph 139). If sheets containing a sequence listing are not numbered or are incorrectly numbered, the receiving Office may either renumber them ex officio or invite the applicant under Rule 26 to do so by submitting replacement sheets (Rule 26.4 and paragraphs 153 to 159). Where sheets are renumbered, the total number of sheets indicated in the check list may need to be corrected and the receiving Office invites the applicant to pay any required additional fee for sheets in excess of the previously calculated total number of sheets (paragraphs 241 and 252 to 265).


226. Tables related to a sequence listing contained in the international application must be included as an integral part of the description. Pages containing such tables are counted as sheets of the international application (paragraph 243).