                         SEQUENCE LISTING

<110>  Bayer Aktiengesellschaft
 
<120>  Cyclic chemerin-9 derivatives

<130>  BHC201036

<160>  20    

<170>  PatentIn version 3.5

<210>  1
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Chemerin-9

<400>  1

Tyr Phe Pro Gly Gln Phe Ala Phe Ser 
1               5                   


<210>  2
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam (= 6-carboxytetramethylrhodamine) modification @ aa position 
       1

<400>  2

Tyr Phe Pro Gly Gln Phe Ala Phe Ser 
1               5                   


<210>  3
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam-EG(4) modification @ aa position 1

<400>  3

Tyr Phe Pro Gly Gln Phe Ala Phe Ser 
1               5                   


<210>  4
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  DISULFID
<222>  (4)..(9)

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<400>  4

Tyr Phe Pro Cys Gln Phe Ala Phe Cys 
1               5                   


<210>  5
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam (= 6-carboxytetramethylrhodamine) modification @ aa position 
       1

<220>
<221>  DISULFID
<222>  (4)..(9)

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<400>  5

Tyr Phe Pro Cys Gln Phe Ala Phe Cys 
1               5                   


<210>  6
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  DISULFID
<222>  (4)..(7)

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<400>  6

Tyr Phe Pro Cys Gln Phe Cys Phe Ser 
1               5                   


<210>  7
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (4)..(9)
<223>  Amino acid side chains @ aa positions 4 and 9 connected via CH2 
       group

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<400>  7

Tyr Phe Pro Cys Gln Phe Ala Phe Cys 
1               5                   


<210>  8
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam (= 6-carboxytetramethylrhodamine) modification @ aa position 
       1

<220>
<221>  MISC_FEATURE
<222>  (4)..(9)
<223>  Amino acid side chains @ aa positions 4 and 9 connected via CH2 
       group

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<400>  8

Tyr Phe Pro Cys Gln Phe Ala Phe Cys 
1               5                   


<210>  9
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<220>
<221>  MISC_FEATURE
<222>  (4)..(9)
<223>  Amino acids side chains at positions 4 and 9 connected via CH2 
       group

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa @ aa position 9 is D-homocysteine

<400>  9

Tyr Phe Pro Cys Gln Phe Ala Phe Xaa 
1               5                   


<210>  10
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam (= 6-carboxytetramethylrhodamine) modification @ aa position 
       1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<220>
<221>  MISC_FEATURE
<222>  (4)..(9)
<223>  Amino acid side chains at positions 4 and 9 connected via CH2 
       group

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa @ aa position 9 is D-homocysteine

<400>  10

Tyr Phe Pro Cys Gln Phe Ala Phe Xaa 
1               5                   


<210>  11
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  D-tyrosine @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<220>
<221>  MISC_FEATURE
<222>  (4)..(9)
<223>  Amino acid side chains at positions 4 and 9 connected via CH2 
       group

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa @ aa position 9 is D-homocysteine

<400>  11

Tyr Phe Pro Cys Gln Phe Ala Phe Xaa 
1               5                   


<210>  12
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  D-tyrosine @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  D-cysteine @ aa position 4

<220>
<221>  DISULFID
<222>  (4)..(9)

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Lys side chain @ aa position 7 modified with Tam

<400>  12

Tyr Phe Pro Cys Gln Phe Lys Phe Cys 
1               5                   


<210>  13
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  13

Tyr Phe Pro Xaa Gln Phe Ala Phe Cys 
1               5                   


<210>  14
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  14

Tyr Phe Pro Xaa Gln Phe Ala Trp Cys 
1               5                   


<210>  15
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  D-tyrosine @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  15

Tyr Phe Pro Xaa Gln Phe Ala Trp Cys 
1               5                   


<210>  16
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  EG(4) modification @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  16

Tyr Phe Pro Xaa Gln Phe Ala Phe Cys 
1               5                   


<210>  17
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam-EG(4) modification @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  17

Tyr Phe Pro Xaa Gln Phe Ala Phe Cys 
1               5                   


<210>  18
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  EG(4) modification @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  18

Tyr Phe Pro Xaa Gln Phe Ala Trp Cys 
1               5                   


<210>  19
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Tam-EG(4) modification @ aa position 1

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  Xaa @ aa position 4 is D-homocysteine

<220>
<221>  DISULFID
<222>  (4)..(9)

<400>  19

Tyr Phe Pro Xaa Gln Phe Ala Trp Cys 
1               5                   


<210>  20
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>   peptide derived from chemerin-9


<220>
<221>  MOD_RES
<222>  (1)..(1)
<223>  ACETYLATION

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Xaa @ aa position 8 is D-homocysteine

<220>
<221>  DISULFID
<222>  (8)..(13)

<400>  20

Gly Phe Leu Gly Tyr Phe Pro Xaa Gln Phe Ala Phe Cys 
1               5                   10              


