                         SEQUENCE LISTING

<110>  Eli Lilly and Company
 
<120>  GIP/GLP1 Co-Agonist Compounds

<130>  X22152

<150>  US 62/964932
<151>  2020-01-23

<160>  511   

<170>  PatentIn version 3.5

<210>  1
<211>  42
<212>  PRT
<213>  Homo sapiens


<220>
<221>  MOD_RES
<222>  (42)..(42)
<223>  Ser at position 42 is amidated

<400>  1

Tyr Ala Glu Gly Thr Phe Ile Ser Asp Tyr Ser Ile Ala Met Asp Lys 
1               5                   10                  15      


Ile His Gln Gln Asp Phe Val Asn Trp Leu Leu Ala Gln Lys Gly Lys 
            20                  25                  30          


Lys Asn Asp Trp Lys His Asn Ile Thr Gln 
        35                  40          


<210>  2
<211>  29
<212>  PRT
<213>  Homo sapiens

<400>  2

His Ser Gln Gly Thr Phe Thr Ser Asp Tyr Ser Lys Tyr Leu Asp Ser 
1               5                   10                  15      


Arg Arg Ala Gln Asp Phe Val Gln Trp Leu Met Asn Thr 
            20                  25                  


<210>  3
<211>  30
<212>  PRT
<213>  Homo sapiens


<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Ser at position 30 is amidated

<400>  3

His Ala Glu Gly Thr Phe Thr Ser Asp Val Ser Ser Tyr Leu Glu Gly 
1               5                   10                  15      


Gln Ala Ala Lys Glu Phe Ile Ala Trp Leu Val Lys Gly Arg 
            20                  25                  30  


<210>  4
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct; a compound of Formula II


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position in is Y or R1-Y, wherein R1 is an Ac modification
       of the N-terminal amino group

<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F or alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is K, 4Pal, Y, alpha-methyl-F, 
       alpha-methyl-F(2F), alpha-methyl-L, alpha-methyl-V, Ac4c, Ac5c, 
       Ac6c, Bip, 1Nal, 2Nal, OMeY, hTyr, Nle, V, 4CPhe, ChG, ChA, Bzt, 
       2FA, 4TAA, 2TA, 3TA, or KZ1

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Ac5c, S, alpha-methyl-S, Aib, G, Dap, or 
       Tle

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Xaa at position 12 is I or KZ1

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-MeL or alpha-methyl-F

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (17)..(17)
<223>  Xaa at position 17 is Q, I, or KZ1

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib, Orn, 4Pal, alpha-methyl-F, Ac5c, or 
       Ac6c

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is E, KZ1, G, Orn, or 4Pal

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is F, 2ClPhe, 3ClPhe, 2FPhe, 3FPhe, 3,5FPhe, 
       1Nal, 2Nal, alpha-methyl-F(2F), ChA, Bzt, or alpha-methyl-F

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu, E, G, or KZ1

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is Y, alpha-methyl-Y, alpha-methyl-F, or KZ1

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is E, Orn, or KZ1

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  Xaa at position 30 is G, Orn, KZ1, or GR2, and a modification of 
       the c-terminal group wherein the modification is NH2

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  When Xaa at position 30 is GR2, then R2 is SEQ ID NO:5, SEQ ID 
       NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, or SEQ ID NO:10

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  When Xaa at position 30 is KZ1, Z1 is R5 or R4R5, wherein R4 is a
       linker and R5 is a fatty acid

<400>  4

Xaa Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Xaa Xaa Leu Asp Xaa 
1               5                   10                  15      


Xaa Ala Gln Xaa Xaa Xaa Ile Xaa Xaa Leu Ile Xaa Gly Xaa 
            20                  25                  30  


<210>  5
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<400>  5

Xaa Ser Ser Gly 
1               


<210>  6
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<220>
<221>  MOD_RES
<222>  (4)..(4)
<223>  Xaa at position 4 is modified with R3, where R3 is is a 
       modification of the C-terminal group, wherein the modification is
       NH2

<400>  6

Xaa Ser Ser Gly 
1               


<210>  7
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is A or Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is S or Orn

<400>  7

Xaa Ser Ser Gly Xaa Pro Pro Pro Xaa 
1               5                   


<210>  8
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is A or Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is S or Orn

<220>
<221>  MOD_RES
<222>  (9)..(9)
<223>  Xaa at position 9 is modified with R3, where R3 is is a 
       modification of the C-terminal group, wherein the modification is
       NH2

<400>  8

Xaa Ser Ser Gly Xaa Pro Pro Pro Xaa 
1               5                   


<210>  9
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is A or Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is S or Orn

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is KZ1

<400>  9

Xaa Ser Ser Gly Xaa Pro Pro Pro Xaa Xaa 
1               5                   10  


<210>  10
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 is P or KZ1

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is A or Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is S or Orn

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is KZ1

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Xaa at position 10 is modified with R3, where R3 is is a 
       modification of the C-terminal group, wherein the modification is
       NH2

<400>  10

Xaa Ser Ser Gly Xaa Pro Pro Pro Xaa Xaa 
1               5                   10  


<210>  11
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  11

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  12
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-L

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  12

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  13
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-iodophe
       nyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-iodophe
       nyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  13

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  14
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  14

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  15
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-F(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  15

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  16
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  16

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  17
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  17

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  18
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  18

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  19
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  19

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  20
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2--(10-(4-carboxyphenoxy)de
       canoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2--(10-(4-carboxyphenoxy)de
       canoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  20

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  21
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  21

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  22
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  22

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  23
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)14-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)14-CH3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  23

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  24
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  24

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  25
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  25

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  26
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  26

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  27
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(20)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  misc_feature
<222>  (24)..(24)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  27

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  28
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Lys at position 30 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  28

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Lys Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  29
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  29

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  30
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  30

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  31
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  31

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  32
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  32

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  33
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  33

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  34
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Lys at position 30 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  34

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Lys Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  35
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  35

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  36
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Lys at position 30 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  36

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  37
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  37

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  38
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MOD_RES
<222>  (12)..(12)
<223>  Lys at position 12 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  38

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Lys Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  39
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  39

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  40
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  40

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  41
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  41

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  42
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MOD_RES
<222>  (25)..(25)
<223>  Lys at position 25 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  42

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Lys Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  43
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys-)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys-)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  43

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  44
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-(gamma-Glu)
       -CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(25)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-(gamma-Glu)
       -CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  44

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  45
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(epsilon-Lys)-(gamma-Glu)-
       CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(epsilon-Lys)-(gamma-Glu)-
       CO-(CH2)12-CO2H

<400>  45

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  46
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-
       CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-
       CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  46

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  47
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)
       -CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)
       -CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  47

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  48
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  48

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  49
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  49

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  50
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  50

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  51
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  51

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  52
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  52

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  53
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  53

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  54
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  54

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  55
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position10 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  55

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  56
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  56

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  57
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  57

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  58
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  58

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  59
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  59

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  60
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  60

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  61
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  61

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  62
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is alpha-methyl-Val

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  62

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  63
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  63

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  64
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac6c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  64

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  65
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Bip

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  65

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  66
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 1Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  66

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  67
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  67

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  68
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  68

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  69
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  69

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  70
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  70

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  71
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 2ClPhe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  71

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  72
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 3ClPhe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  72

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  73
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 2FPhe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  73

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  74
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 3FPhe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  74

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  75
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 3,5FPhe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  75

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  76
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 1Nal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  76

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  77
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MOD_RES
<222>  (25)..(25)
<223>  Lys at position 25 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  77

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Lys Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  78
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (25)..(25)
<223>  Lys at position 25 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  78

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Glu Lys Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  79
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  79

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  80
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  80

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  81
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  81

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  82
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  82

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  83
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  83

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  84
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  84

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  85
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  85

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  86
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  86

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  87
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  87

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  88
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  88

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  89
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  89

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  90
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  90

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  91
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  91

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  92
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  92

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  93
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  93

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  94
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  94

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  95
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  95

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Tyr Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  96
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  96

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  97
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  97

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  98
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  98

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  99
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  99

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  100
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  100

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  101
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  101

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  102
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  102

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  103
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  103

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  104
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  104

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  105
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac4c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  105

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  106
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4CPhe

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  106

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  107
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is ChG

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  107

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  108
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is ChA

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  108

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  109
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  109

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  110
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  110

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Gly Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  111
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  111

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Gly 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  112
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  112

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Gly Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  113
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  113

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Gly Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  114
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  114

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Gly Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  115
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  115

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  116
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  116

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  117
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  117

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  118
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  118

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  119
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  119

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  120
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  120

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  121
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  121

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  122
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  122

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  123
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  123

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  124
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  124

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  125
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  125

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  126
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  126

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  127
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  127

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  128
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  128

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  129
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  129

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  130
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  130

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  131
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  131

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  132
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  132

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  133
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  133

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  134
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  134

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  135
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(7-(4-carboxy
       phenoxy)heptanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(7-(4-carboxy
       phenoxy)heptanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  135

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  136
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(8-(4-carboxy
       phenoxy)octanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(8-(4-carboxy
       phenoxy)octanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  136

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  137
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  137

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  138
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  138

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  139
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  139

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  140
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  140

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  141
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  141

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  142
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  142

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  143
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  143

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  144
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Lys at position 30 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  144

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Lys Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  145
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Ser at position 40 is amidated

<400>  145

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  146
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  146

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  147
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  147

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  148
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  148

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  149
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  149

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  150
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Lys at position 30 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  150

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Lys Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  151
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  151

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  152
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Bzt

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  152

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  153
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2FA

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  153

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  154
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4TAA

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  154

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  155
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2TA

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  155

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  156
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 3TA

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  156

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  157
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is Bzt

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  157

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  158
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is ChA

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  158

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  159
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  159

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  160
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  160

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  161
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  161

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  162
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  Xaa at position 30 is Orn

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  162

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Xaa Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  163
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (35)..(35)
<223>  Xaa at position 35 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  163

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Xaa Pro Pro Pro Ser 
        35                  


<210>  164
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (39)..(39)
<223>  Xaa at position 39 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Orn at position 39 is amidated

<400>  164

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Xaa 
        35                  


<210>  165
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (35)..(35)
<223>  Xaa at position 35 is Orn

<220>
<221>  MISC_FEATURE
<222>  (39)..(39)
<223>  Xaa at position 39 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Orn at position 39 is amidated

<400>  165

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Xaa Pro Pro Pro Xaa 
        35                  


<210>  166
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  166

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  167
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  167

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  168
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  168

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Glu Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  169
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  169

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Glu Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  170
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  170

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  171
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  171

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  172
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  172

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  173
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  173

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  174
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  174

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  175
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  175

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  176
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  176

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  177
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  177

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  178
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  178

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  179
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  179

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  180
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  180

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  181
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Ac6c

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  181

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  182
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  182

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  183
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  183

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  184
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Phe

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  184

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  185
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  185

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  186
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  186

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  187
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  187

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  188
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  188

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  189
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  189

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  190
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  190

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  191
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  191

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  192
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  192

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  193
<211>  34
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (34)..(34)
<223>  Gly at position 34 is amidated

<400>  193

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly 
        


<210>  194
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is amidated

<400>  194

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys 
            20                  25                  30      


<210>  195
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(epsilon-Lys)-CO-(CH2)12-
       CO2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is amidated

<400>  195

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys 
            20                  25                  30      


<210>  196
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is amidated

<400>  196

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys 
            20                  25                  30      


<210>  197
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is amidated

<400>  197

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys 
            20                  25                  30      


<210>  198
<211>  34
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (34)..(34)
<223>  Gly at position 34 is amidated

<400>  198

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly 
        


<210>  199
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Gly at position 30 is amidated

<400>  199

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly 
            20                  25                  30  


<210>  200
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  Xaa at position 30 is Orn

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Orn at position 30 is amidated

<400>  200

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Xaa 
            20                  25                  30  


<210>  201
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  201

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  202
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  202

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  203
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  203

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  204
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  204

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  205
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  205

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  206
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  206

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  207
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  207

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  208
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (epsilon-Lys)-(epsilon-Lys)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  208

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  209
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Dap

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  209

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  210
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Dap

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  210

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  211
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Dap

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  211

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  212
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Tle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  212

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  213
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  213

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  214
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  214

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  215
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  215

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  216
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  216

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  217
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(4-(4-tert-bu
       tylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  217

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  218
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(4-(4-tert-but
       ylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(4-(4-tert-but
       ylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  218

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  219
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(4-(4-tert-but
       ylphenyl)butanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(4-(4-tert-but
       ylphenyl)butanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  219

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  220
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  220

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  221
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Ac5c

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  221

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  222
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  222

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  223
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (31)..(31)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  223

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Lys Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  224
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  224

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  225
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  225

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  226
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  226

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  227
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  227

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  228
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  228

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  229
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  229

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  230
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  230

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  231
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  231

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  232
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  232

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  233
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  233

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  234
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  234

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  235
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  235

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  236
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  236

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  237
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  237

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  238
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  238

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  239
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  239

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  240
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  240

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  241
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  241

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  242
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  242

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  243
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  243

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  244
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  244

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  245
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  245

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  246
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  246

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  247
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  247

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  248
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  248

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  249
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  249

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  250
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  250

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  251
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  251

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  252
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  252

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  253
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  253

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  254
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  254

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  255
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  255

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  256
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  256

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  257
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  257

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  258
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  258

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  259
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  259

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  260
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  260

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  261
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  261

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  262
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  262

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  263
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  263

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  264
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  264

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  265
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  265

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  266
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  266

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  267
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  267

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  268
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  268

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  269
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  269

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  270
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  270

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  271
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  271

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  272
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  272

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  273
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  273

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  274
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  274

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  275
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  275

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  276
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  276

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  277
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  277

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  278
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  278

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  279
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  279

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  280
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  280

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  281
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  281

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  282
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  282

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  283
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  283

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  284
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  284

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  285
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  285

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  286
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  286

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  287
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  287

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  288
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  288

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  289
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  289

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  290
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  290

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  291
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  291

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  292
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  292

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  293
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  293

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  294
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 2Nal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  294

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  295
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  295

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  296
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  296

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  297
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  297

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  298
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  298

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  299
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  299

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  300
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 31 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  300

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  301
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is OMeY

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  301

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  302
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  302

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  303
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  303

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  304
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Gly at position 30 is amidated

<400>  304

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly 
            20                  25                  30  


<210>  305
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Gly at position 30 is amidated

<400>  305

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly 
            20                  25                  30  


<210>  306
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Gly at position 30 is amidated

<400>  306

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly 
            20                  25                  30  


<210>  307
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (30)..(30)
<223>  Gly at position 30 is amidated

<400>  307

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly 
            20                  25                  30  


<210>  308
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  308

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  309
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  309

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  310
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  310

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  311
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  311

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  312
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  312

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  313
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  313

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  314
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  314

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  315
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  315

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  316
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  316

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  317
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  317

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  318
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  318

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  319
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is alpha-methyl-Ser

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  319

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  320
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  320

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  321
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  321

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  322
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  322

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  323
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  323

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  324
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  324

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  325
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  325

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  326
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  326

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  327
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  327

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  328
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  328

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  329
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  329

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  330
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  330

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  331
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  331

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  332
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  332

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  333
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  333

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  334
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  334

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  335
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  335

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  336
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  336

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  337
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  337

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  338
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  338

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  339
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  339

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  340
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  340

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  341
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  341

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  342
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  342

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  343
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  343

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  344
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  344

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  345
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  345

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  346
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  346

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  347
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  347

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  348
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  348

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  349
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  349

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  350
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  350

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  351
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  351

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  352
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  352

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  353
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  353

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  354
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  354

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  355
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  355

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  356
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  356

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  357
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  357

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  358
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  358

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  359
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  359

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  360
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  360

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  361
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  361

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  362
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  362

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  363
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  363

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  364
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  364

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  365
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  365

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  366
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  366

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  367
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  367

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  368
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  368

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  369
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  369

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  370
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  370

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  371
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  371

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  372
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  372

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  373
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(2-[2-(2-amin
       o-ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(2-[2-(2-amin
       o-ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  373

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  374
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  374

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  375
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  375

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  376
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  376

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  377
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  377

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  378
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  378

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  379
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  379

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  380
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  380

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  381
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  381

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  382
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  382

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  383
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  383

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  384
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  384

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  385
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  385

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  386
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  386

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  387
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  387

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  388
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  388

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  389
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  389

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  390
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  390

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  391
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  391

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  392
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  392

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  393
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  393

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  394
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  394

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  395
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  395

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  396
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  396

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  397
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  397

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  398
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  398

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  399
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  399

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  400
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  400

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  401
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  401

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  402
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  402

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Lys Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  403
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  403

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  404
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  404

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  405
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  405

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  406
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  406

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  407
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(10-(4-carboxyphenoxy)dec
       anoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  407

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  408
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  408

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  409
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  409

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  410
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  410

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  411
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  411

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  412
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  412

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  413
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  413

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  414
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  414

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  415
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG4-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG4-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  415

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  416
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  416

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  417
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  417

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  418
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  418

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  419
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  419

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  420
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  420

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  421
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  421

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  422
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  422

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  423
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  423

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  424
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  424

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  425
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  425

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  426
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  426

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  427
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  427

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  428
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  428

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  429
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  429

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Thr Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  430
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  430

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  431
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  431

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  432
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  432

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  433
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  433

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  434
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  434

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  435
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  435

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  436
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  436

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  437
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  437

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  438
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)10-CH3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  438

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  439
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  439

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  440
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  440

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  441
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  441

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  442
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  442

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  443
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is Orn

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  443

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Xaa Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  444
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  444

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  445
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  445

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Xaa Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  446
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  446

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  447
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  447

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Lys Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  448
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  448

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  449
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  449

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Xaa Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  450
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  450

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  451
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  451

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Gly Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  452
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(11-(4-carbox
       yphenoxy)undecanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  452

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  453
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)14-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  453

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  454
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  454

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  455
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Lys at position 10 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  455

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Lys Xaa Ile Xaa Leu Asp Gly 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  456
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  456

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  457
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  457

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  458
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  458

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Val Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  459
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Ahx-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Ahx-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  459

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  460
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  460

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  461
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Ahx-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Ahx-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  461

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  462
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Aoc-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Aoc-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  462

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  463
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Ahx-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Ahx-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  463

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  464
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  464

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  465
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Ahx-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Ahx-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  465

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  466
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Aoc-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       Aoc-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  466

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  467
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG4-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG4-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  467

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  468
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  468

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  469
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2
       H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  469

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  470
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  470

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  471
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (PEG4-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (PEG4-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  471

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  472
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG3-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  472

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  473
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxy
       phenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  473

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  474
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  474

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Glu Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  475
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Aoc-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  475

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Glu Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  476
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG6-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG6-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  476

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  477
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG5-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG5-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  477

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  478
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG6-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG6-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  478

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  479
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG5-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       PEG5-(gamma-Glu)-(10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  479

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  480
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-Trx-(gamma-Glu)-CO-(CH2)1
       2-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-Trx-(gamma-Glu)-CO-(CH2)1
       2-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  480

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  481
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-Trx-(gamma-Glu)-(10-(4-ca
       rboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-Trx-(gamma-Glu)-(10-(4-ca
       rboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  481

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  482
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Trx-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Trx-(gamma-Glu)-CO-(CH2)12
       -CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  482

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  483
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Trx-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-Trx-(gamma-Glu)-(10-(4-car
       boxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  483

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  484
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-CO-(CH2)12-C
       O2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-CO-(CH2)12-C
       O2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  484

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  485
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-(10-(4-carbo
       xyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-(10-(4-carbo
       xyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  485

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  486
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  486

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  487
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  487

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  488
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  488

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  489
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  489

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  490
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-CO-(CH2)12-C
       O2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)2-CO-(CH2)12-C
       O2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  490

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  491
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)3-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  491

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Ile Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  492
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-C
       O-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-C
       O-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  492

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  493
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(
       10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (gamma-Glu)-(2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(
       10-(4-carboxyphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  493

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  494
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-CO-(CH2)12-CO2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  494

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  495
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxyphenoxy)decano
       

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(2-[2-(2-amino
       -ethoxy)-ethoxy]-acetyl)-(gamma-Glu)-(10-(4-carboxyphenoxy)decano
       

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  495

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  496
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)3-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)3-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  496

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  497
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)3-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)-(gamma-Glu)3-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  497

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  498
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  498

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  499
<211>  40
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is AIB

<220>
<221>  MOD_RES
<222>  (21)..(21)
<223>  Lys at position 21 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (40)..(40)
<223>  Lys at position 40 is amidated

<400>  499

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Lys Phe Ile Xaa Xaa Leu Ile Glu Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser Lys 
        35                  40  


<210>  500
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is Nle

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  500

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  501
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is hTyr

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)12-CO
       2H

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  501

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Ser Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  502
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is Orn

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  502

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Tyr Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  503
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is 4Pal

<220>
<221>  MOD_RES
<222>  (24)..(24)
<223>  Lys at position 24 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-(10-(4-carbox
       yphenoxy)decanoyl)

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  503

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Gln Ala Gln Xaa Xaa Phe Ile Lys Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  504
<211>  39
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 is alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is 4Pal

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is Aib

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is alpha-methyl-Leu

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MOD_RES
<222>  (17)..(17)
<223>  Lys at position 17 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is Aib

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is D-Glu

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is alpha-methyl-Tyr

<220>
<221>  MOD_RES
<222>  (28)..(28)
<223>  Lys at position 28 is chemically modified by conjugation of the 
       epsilon-amino group of the Lys side chain with 
       (2-[2-(2-amino-ethoxy)-ethoxy]-acetyl)2-(gamma-Glu)-CO-(CH2)10-CH
       3

<220>
<221>  MOD_RES
<222>  (39)..(39)
<223>  Ser at position 39 is amidated

<400>  504

Tyr Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Ile Xaa Leu Asp Xaa 
1               5                   10                  15      


Lys Ala Gln Xaa Gly Phe Ile Xaa Xaa Leu Ile Lys Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210>  505
<211>  30
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct; a compound of Formula I


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Xaa at position 1 selected from the group consisting of Y or R1Y,
       wherein R1 is an acetyl modification of the N-terminal amino 
       group of Y

<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa at position 2 is Aib

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Xaa at position 6 iis selected from the group consisting of 
       alpha-methyl-Phe and alpha-methyl-Phe(2F)

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is selected from the group consisting of 4Pal,
       Y, alpha-methyl-Phe, alpha-methyl-Phe(2F), alpha-methyl-Leu, 
       alpha-methyl-Val, Ac4c, Ac5c, Ac6c, Bip, 1Nal, 2Nal, OMeY, hTyr, 
       Nle, V, 4CPhe, ChG, ChA, Bzt, 2FA, 4TAA, 2TA, 3TA, and KZ1

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (10)..(30)
<223>  wherein two, and only two, of X10, X12, X17, X21, X24, X25, X28, 
       X30, X31, and X40 are KZ1 or K(Z1)R6

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Xaa at position 11 is selected from the group consisting of S, 
       alpha-methyl-Ser, Aib, G, Dap, Ac5c, and Tle

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Xaa at position 12 is selected from the group consisting of I and
       KZ1

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Xaa at position 13 is selected from the group consisting of 
       alpha-methyl-Leu and alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (16)..(16)
<223>  Xaa at position 16 is Orn

<220>
<221>  MISC_FEATURE
<222>  (17)..(17)
<223>  Xaa at position 17 is selected from the group consisting of Q, I,
       and KZ1

<220>
<221>  MISC_FEATURE
<222>  (17)..(17)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (20)..(20)
<223>  Xaa at position 20 is selected from the group consisting of Aib, 
       Orn, 4Pal, alpha-methyl-Phe, Ac5c, and Ac6c

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Xaa at position 21 is selected from the group consisting of E, 
       KZ1, G, Orn, and 4Pal

<220>
<221>  MISC_FEATURE
<222>  (21)..(21)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (22)..(22)
<223>  Xaa at position 22 is selected from the group consisting of F, 
       2ClPhe, 3ClPhe, 2FPhe, 3FPhe, 3,5FPhe, 1Nal, 2Nal, 
       alpha-methyl-Phe(2F), ChA, Bzt, and alpha-methyl-Phe

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Xaa at position 24 is selected from the group consisting of 
       D-Glu, E, G, and KZ1

<220>
<221>  MISC_FEATURE
<222>  (24)..(24)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Xaa at position 25 is selected from the group consisting of Y, 
       alpha-methyl-Tyr, alpha-methyl-Phe, and KZ1

<220>
<221>  MISC_FEATURE
<222>  (25)..(25)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Xaa at position 28 is selected from the group consisting of E, 
       Orn, and KZ1

<220>
<221>  MISC_FEATURE
<222>  (28)..(28)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  Xaa at position 30 is selected from the group consisting of G, 
       Orn, KZ1, K(Z1)R6, OrnR2, and GR2

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  R2 is selected from the group consisting of X31, SEQ ID NO:5, SEQ
       ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, and
       a modification of the C-terminal group wherein the modification 
       is NH2

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  R6 is selected from the group consisting of SEQ ID NO:506, SEQ ID
       NO:507, SEQ ID NO:508, SEQ ID NO:509, SEQ ID NO:510, SEQ ID 
       NO:511, and a modification of the C-terminal group wherein the 
       modification is NH2

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  X31 is selected from the group consisting of P and KZ1; X35 is 
       selected from the group consisting of A and Orn; X39 is selected 
       from the group consisting of S and Orn; X40 is KZ1

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  R3 is a modification of the C-terminal group, wherein the 
       modification is NH2

<220>
<221>  MISC_FEATURE
<222>  (30)..(30)
<223>  Z1 is selected from the group consisting of R5 and -R4R5; R4 is a
       linker; and R5 is a fatty acid

<400>  505

Xaa Xaa Glu Gly Thr Xaa Thr Ser Asp Xaa Xaa Xaa Xaa Leu Asp Xaa 
1               5                   10                  15      


Xaa Ala Gln Xaa Xaa Xaa Ile Xaa Xaa Leu Ile Xaa Gly Xaa 
            20                  25                  30  


<210>  506
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  506

Pro Ser Ser Gly 
1               


<210>  507
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MOD_RES
<222>  (4)..(4)
<223>  Gly is modified with R3; wherein R3 is a modification of the 
       C-terminal group, wherein the modification is NH2

<400>  507

Pro Ser Ser Gly 
1               


<210>  508
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is selected from the group consisting of A and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is selected from the group consisting of S and 
       Orn

<400>  508

Pro Ser Ser Gly Xaa Pro Pro Pro Xaa 
1               5                   


<210>  509
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is selected from the group consisting of A and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is selected from the group consisting of S and 
       Orn

<220>
<221>  MOD_RES
<222>  (9)..(9)
<223>  Xaa at position 9 is modified with R3; wherein R3 is a 
       modification of the C-terminal group, wherein the modification is
       NH2

<400>  509

Pro Ser Ser Gly Xaa Pro Pro Pro Xaa 
1               5                   


<210>  510
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is selected from the group consisting of A and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is selected from the group consisting of S and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is KZ1; wherein Z1 is selected from the group 
       consisting of R5 and -R4R5; R4 is a linker; and R5 is a fatty 
       acid

<400>  510

Pro Ser Ser Gly Xaa Pro Pro Pro Xaa Xaa 
1               5                   10  


<210>  511
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  Xaa at position 5 is selected from the group consisting of A and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (9)..(9)
<223>  Xaa at position 9 is selected from the group consisting of S and 
       Orn

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is KZ1; wherein Z1 is selected from the group 
       consisting of R5 and -R4R5; R4 is a linker; and R5 is a fatty 
       acid

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Xaa at position 10 is modified with R3; wherein R3 is a 
       modification of the C-terminal group, wherein the modification is
       NH2

<400>  511

Pro Ser Ser Gly Xaa Pro Pro Pro Xaa Xaa 
1               5                   10  


