                         SEQUENCE LISTING

<110>  Biogen MA Inc.
 
<120>  COMBINATION THERAPY FOR SPINAL MUSCULAR ATROPHY

<130>  B1152.70095WO00

<140>  Not yet assigned
<141>  Concurrently herewith

<150>  US 62/887,579
<151>  2019-08-15

<160>  26    

<170>  PatentIn version 3.5

<210>  1
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  1
tcactttcat aatgctgg                                                     18


<210>  2
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  2
tgctggcaga cttac                                                        15


<210>  3
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  3
cataatgctg gcaga                                                        15


<210>  4
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  4
tcataatgct ggcag                                                        15


<210>  5
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  5
ttcataatgc tggca                                                        15


<210>  6
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  6
tttcataatg ctggc                                                        15


<210>  7
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  7
attcactttc ataatgctgg                                                   20


<210>  8
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  8
ctttcataat gctgg                                                        15


<210>  9
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  9
tcataatgct gg                                                           12


<210>  10
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  10
actttcataa tgctg                                                        15


<210>  11
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  11
ttcataatgc tg                                                           12


<210>  12
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  12
cactttcata atgct                                                        15


<210>  13
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  13
tttcataatg ct                                                           12


<210>  14
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  14
tcactttcat aatgc                                                        15


<210>  15
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  15
ctttcataat gc                                                           12


<210>  16
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  16
ttcactttca taatg                                                        15


<210>  17
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  17
actttcataa tg                                                           12


<210>  18
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  18
attcactttc ataat                                                        15


<210>  19
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  19
cactttcata at                                                           12


<210>  20
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  20
gattcacttt cataa                                                        15


<210>  21
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  21
tcactttcat aa                                                           12


<210>  22
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  22
ttcactttca ta                                                           12


<210>  23
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  23
attcactttc at                                                           12


<210>  24
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  24
agtaagattc acttt                                                        15


<210>  25
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidine

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  2'-O-(2-methoxyethyl)-P-thioadenine

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidine

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  2'-O-(2-methoxyethyl)-P-thioadenine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  2'-O-(2-methoxyethyl)-P-thioadenine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  2'-O-(2-methoxyethyl)-P-thioadenine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  2'-O-(2-methoxyethyl)-P-thioguanine

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidine

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  2'-O-(2-methoxyethyl)-5-methyl-P-thiouridine

<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  2'-O-(2-methoxyethyl)-P-thioguanine

<220>
<221>  misc_feature
<222>  (18)..(18)
<223>  2'-O-(2-methoxyethyl)-P-thioguanine

<400>  25
ucacuuucau aaugcugg                                                     18


<210>  26
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic polynucleotide

<400>  26
ucacuuucau aaugcugg                                                     18


