                         SEQUENCE LISTING

<110>  F. Hoffmann-La Roche AG
       Roche Diagnostics GmbH
 
<120>  Hybridizing all-LNA oligonucleotides

<130>  P35591-WO (MI)

<150>  EP19179046.8
<151>  2019-06-07

<160>  70    

<170>  PatentIn version 3.5

<210>  1
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  1
tgctcctg                                                                 8


<210>  2
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  2
caggagca                                                                 8


<210>  3
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  3
gcctgacg                                                                 8


<210>  4
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  4
cgtcaggc                                                                 8


<210>  5
<211>  10
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  5
ctgcctgacg                                                              10


<210>  6
<211>  10
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  6
cgtcaggcag                                                              10


<210>  7
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  7
gactgcctga cg                                                           12


<210>  8
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  8
cgtcaggcag tc                                                           12


<210>  9
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  9
tgctcctgt                                                                9


<210>  10
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  10
acaggagca                                                                9


<210>  11
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  11
gtgcgtct                                                                 8


<210>  12
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  12
agacgcac                                                                 8


<210>  13
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  13
gttggtgt                                                                 8


<210>  14
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  14
acaccaac                                                                 8


<210>  15
<211>  7
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  15
caggagc                                                                  7


<210>  16
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  16
gttggt                                                                   6


<210>  17
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  17
caacacacca ac                                                           12


<210>  18
<211>  10
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  18
acacaccaac                                                              10


<210>  19
<211>  7
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  19
caccaac                                                                  7


<210>  20
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  20
accaac                                                                   6


<210>  21
<211>  7
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  21
gttggtg                                                                  7


<210>  22
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  22
gttggtgtg                                                                9


<210>  23
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  23
gttggtgtgt tg                                                           12


<210>  24
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  24
ttttttttt                                                                9


<210>  25
<211>  8
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  25
tttttttt                                                                 8


<210>  26
<211>  7
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  26
ttttttt                                                                  7


<210>  27
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  27
tttttt                                                                   6


<210>  28
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  28
aaaaaaaaa                                                                9


<210>  29
<211>  4
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  29
tttt                                                                     4


<210>  30
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  30
cacaccaac                                                                9


<210>  31
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  31
gttggtgtgt tggtg                                                        15


<210>  32
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  32
caccaacaca ccaac                                                        15


<210>  33
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  33
cttcc                                                                    5


<210>  34
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  34
ggaag                                                                    5


<210>  35
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  35
tcttcc                                                                   6


<210>  36
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  36
ggaaga                                                                   6


<210>  37
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  37
ttctcttcc                                                                9


<210>  38
<211>  9
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  38
ggaagagaa                                                                9


<210>  39
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  39
aaaaaa                                                                   6


<210>  40
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  40
ctgtca                                                                   6


<210>  41
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  41
tgacag                                                                   6


<210>  42
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  42
gctcc                                                                    5


<210>  43
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  43
ggagc                                                                    5


<210>  44
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  44
tgctcc                                                                   6


<210>  45
<211>  6
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  45
ggagca                                                                   6


<210>  46
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  46
ccaac                                                                    5


<210>  47
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  47
cgtcaggcag ttcag                                                        15


<210>  48
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  48
ctgaactgcc tgacg                                                        15


<210>  49
<211>  4
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  49
tttt                                                                     4


<210>  50
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  50
gttggtgtgt tggtg                                                        15


<210>  51
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  51
cttcc                                                                    5


<210>  52
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  52
caacacacca ac                                                           12


<210>  53
<211>  12
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  53
gttggtgtgt tg                                                           12


<210>  54
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  54
caccaacaca ccaac                                                        15


<210>  55
<211>  15
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  55
cgtcaggcag ttcag                                                        15


<210>  56
<211>  4
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  56
caac                                                                     4


<210>  57
<211>  5
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  57
ttttt                                                                    5


<210>  58
<211>  4
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  58
tttt                                                                     4


<210>  59
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  59
cagtggacga cgatagacat                                                   20


<210>  60
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  60
atgtctatcg tcgtccactg                                                   20


<210>  61
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  61
agaggatcga ggagtacagg                                                   20


<210>  62
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  62
cctgtactcc tcgatcctct                                                   20


<210>  63
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  63
agaaatggac gagatgctaa                                                   20


<210>  64
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  64
ttagcatctc gtccatttct                                                   20


<210>  65
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  65
actgaacttg tgagaaacgc                                                   20


<210>  66
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  66
gcgtttctca caagttcagt                                                   20


<210>  67
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  67
atggagagtc aggcaagttt                                                   20


<210>  68
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  68
aaacttgcct gactctccat                                                   20


<210>  69
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  69
tgaagatgcg agtgatgaac                                                   20


<210>  70
<211>  20
<212>  LNA
<213>  Artificial Sequence

<220>
<223>  Single-stranded oligonucleotide consisting of either D-LNA or 
       L-LNA monomers; in the sequence of nucleobases a signifies 
       adenine, t signifies thymine, u signifies uracil, g signifies 
       guanine, and any c is either cytosine or 5-methylcytosine.

<400>  70
gttcatcact cgcatcttca                                                   20


