                               SEQUENCE LISTING

<110> THE MCLEAN HOSPITAL CORPORATION
 
<120> AUTOLOGOUS CELL REPLACEMENT THERAPY FOR PARKINSON'S DISEASE

<130> 04843-0068WO1

<140> PCT/US2020/034098
<141> 2020-05-21

<150> 62/949,906
<151> 2019-12-18

<150> 62/852,008
<151> 2019-05-23

<160> 109   

<170> PatentIn version 3.5

<210> 1
<211> 9
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide


<220>
<221> MOD_RES
<222> (5)..(5)
<223> Any amino acid

<400> 1
Gly Asp Val Glu Xaa Asn Pro Gly Pro 
1               5                   


<210> 2
<211> 71
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 2
gcgccagtaa agcagacatt aaactttgat ttctgaaact tgcaggtgat gtagagtcaa       60

atccaggtcc a                                                            71


<210> 3
<211> 72
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 3
ggcagcggaa aacagctgtt gaattttgac cttctcaagt tggcgggaga cgtggagtcc       60

aacccagggc cc                                                           72


<210> 4
<211> 57
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 4
gccactaact tctccctgtt gaaacaagca ggggatgtcg aagagaatcc cgggcca          57


<210> 5
<211> 60
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 5
caatgtacta actacgcttt gttgaaactc gctggcgatg ttgaaagtaa ccccggtcct       60


<210> 6
<211> 72
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 6
ggcggcgggt ccggaggaga gggcagagga agtcttctaa catgcggtga cgtggaggag       60

aatcctggcc ca                                                           72


<210> 7
<211> 81
<212> RNA
<213> Homo sapiens

<400> 7
ccuuggccau guaaaagugc uuacagugca gguagcuuuu ugagaucuac ugcaauguaa       60

gcacuucuua cauuaccaug g                                                 81


<210> 8
<211> 82
<212> RNA
<213> Homo sapiens

<400> 8
ccugccgggg cuaaagugcu gacagugcag auaguggucc ucuccgugcu accgcacugu       60

ggguacuugc ugcuccagca gg                                                82


<210> 9
<211> 82
<212> RNA
<213> Homo sapiens

<400> 9
ugagcccucg gaggacucca uuuguuuuga ugauggauuc uuaugcucca ucaucgucuc       60

aaaugagucu ucagaggguu cu                                                82


<210> 10
<211> 68
<212> RNA
<213> Homo sapiens

<400> 10
cccucgucuu acccagcagu guuugggugc gguugggagu cucuaauacu gccggguaau       60

gauggagg                                                                68


<210> 11
<211> 69
<212> RNA
<213> Homo sapiens

<400> 11
ccaccacuua aacguggaug uacuugcuuu gaaacuaaag aaguaagugc uuccauguuu       60

uggugaugg                                                               69


<210> 12
<211> 73
<212> RNA
<213> Homo sapiens

<400> 12
gcucccuuca acuuuaacau ggaagugcuu ucugugacuu uaaaaguaag ugcuuccaug       60

uuuuaguagg agu                                                          73


<210> 13
<211> 68
<212> RNA
<213> Homo sapiens

<400> 13
ccuuugcuuu aacauggggg uaccugcugu gugaaacaaa aguaagugcu uccauguuuc       60

aguggagg                                                                68


<210> 14
<211> 68
<212> RNA
<213> Homo sapiens

<400> 14
ccucuacuuu aacauggagg cacuugcugu gacaugacaa aaauaagugc uuccauguuu       60

gagugugg                                                                68


<210> 15
<211> 68
<212> RNA
<213> Homo sapiens

<400> 15
ccauuacugu ugcuaauaug caacucuguu gaauauaaau uggaauugca cuuuagcaau       60

ggugaugg                                                                68


<210> 16
<211> 70
<212> RNA
<213> Homo sapiens

<400> 16
uugaagggag aucgaccgug uuauauucgc uuuauugacu ucgaauaaua caugguugau       60

cuuuucucag                                                              70


<210> 17
<211> 67
<212> RNA
<213> Homo sapiens

<400> 17
guggcacuca aacugugggg gcacuuucug cucucuggug aaagugccgc caucuuuuga       60

guguuac                                                                 67


<210> 18
<211> 66
<212> RNA
<213> Homo sapiens

<400> 18
gguaacacuc aaaagauggc ggcacuuuca ccagagagca gaaagugccc ccacaguuug       60

agugcc                                                                  66


<210> 19
<211> 67
<212> RNA
<213> Homo sapiens

<400> 19
gugggccuca aauguggagc acuauucuga uguccaagug gaaagugcug cgacauuuga       60

gcgucac                                                                 67


<210> 20
<211> 69
<212> RNA
<213> Homo sapiens

<400> 20
gggauacuca aaaugggggc gcuuuccuuu uugucuguac ugggaagugc uucgauuuug       60

ggguguccc                                                               69


<210> 21
<211> 23
<212> RNA
<213> Homo sapiens

<400> 21
uaauacugcc ggguaaugau gga                                               23


<210> 22
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 22
gagaaaagag gcccaggagt                                                   20


<210> 23
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 23
cccctacagg gtggaaaaat                                                   20


<210> 24
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 24
ggcagtggac ctcaaagaag                                                   20


<210> 25
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 25
ctatgtcttg gccctgatcc                                                   20


<210> 26
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 26
gggtgataac catggacgag g                                                 21


<210> 27
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 27
acttggacgt ttttggggtc                                                   20


<210> 28
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 28
ataaccatgg acgaggacgg                                                   20


<210> 29
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 29
gcagccaatg caacttggac                                                   20


<210> 30
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 30
gggtagagga cgtgaaagag c                                                 21


<210> 31
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 31
ggagacccgg atgatgatga c                                                 21


<210> 32
<211> 18
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 32
caacagagca agactgtc                                                     18


<210> 33
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 33
ggaaacagtt aaatggccaa                                                   20


<210> 34
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 34
ttttggtatt ggccatccta                                                   20


<210> 35
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 35
gaaaggaaca gagagacagg g                                                 21


<210> 36
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 36
attgccccaa aacttttttg                                                   20


<210> 37
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 37
ttgaagacca gtctgggaag                                                   20


<210> 38
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 38
aacagaacca ataggctatc tatc                                              24


<210> 39
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 39
tacagtaaat cacttggtag gaga                                              24


<210> 40
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 40
catgtacgtt gctatccagg c                                                 21


<210> 41
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 41
ctccttaatg tcacgcacga t                                                 21


<210> 42
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 42
aatgggagtg aacctttggt ca                                                22


<210> 43
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 43
gtcgggatgt gcagtagaca                                                   20


<210> 44
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 44
tcatgaaaca cgaagcctac                                                   20


<210> 45
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 45
cacccttctc tcctttgaag                                                   20


<210> 46
<211> 27
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 46
cctggaaggg ctgaccgacg agatcaa                                           27


<210> 47
<211> 25
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 47
cttcccagcc aggctctgca gctcc                                             25


<210> 48
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 48
acagagggga ggtgcgccag ttcacg                                            26


<210> 49
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 49
acggggtgga cctcgctgca cagatc                                            26


<210> 50
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 50
cgaaggtagt tcgccttgag                                                   20


<210> 51
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 51
cggtgatagt cagccaggtt                                                   20


<210> 52
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 52
cgtggcttac tccccattta                                                   20


<210> 53
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 53
tctcgctgtc tctccctctc                                                   20


<210> 54
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 54
tgtcaagcca tgatggaaaa                                                   20


<210> 55
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 55
ggtgagccag agatgctttc                                                   20


<210> 56
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 56
ggtgctttgg ctgacttttt                                                   20


<210> 57
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 57
gttgctcacg gaggagtagc                                                   20


<210> 58
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 58
accacagtcc atgccatcac                                                   20


<210> 59
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 59
tccaccaccc tgttgctgta                                                   20


<210> 60
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 60
ggtgcaggtg aaaatctggt                                                   20


<210> 61
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 61
gctgctgatg ctgacttctg                                                   20


<210> 62
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 62
aaatgtttgt gttgcggtca                                                   20


<210> 63
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 63
tctggcacag gtgtcttcag                                                   20


<210> 64
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 64
gacctgaagt ggagattcaa cc                                                22


<210> 65
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 65
tgtatgcgat caaccaccag a                                                 21


<210> 66
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 66
gggtgccgga agtcatactc                                                   20


<210> 67
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 67
gctaggatct gtatagcgtt tgg                                               23


<210> 68
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 68
acggcctaaa gatggaggag                                                   20


<210> 69
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 69
cggtagaagc aggtggtctc                                                   20


<210> 70
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 70
caggtggcgg acgtgtgaaa attgagagtg                                        30


<210> 71
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 71
cacgctggat ctgcctgggg actgtg                                            26


<210> 72
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 72
cgagaggacc ccgtggatgc agag                                              24


<210> 73
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 73
ggcggccatc ttcagcttct ccag                                              24


<210> 74
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 74
gggccccatc aacttcaccg tcttcc                                            26


<210> 75
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 75
tgtagtcgat gttccccgcc aggtcc                                            26


<210> 76
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 76
caaaggcaaa caacccactt                                                   20


<210> 77
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 77
tctgctggag gctgaggtat                                                   20


<210> 78
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 78
ttgcctgcta cccttgagac                                                   20


<210> 79
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 79
gggctctgat ctctgcatct ac                                                22


<210> 80
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 80
ctcgctcatt tgttggcga                                                    19


<210> 81
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 81
ggagtcgtgt gctttggact                                                   20


<210> 82
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 82
ccgggccgag aaaggtatg                                                    19


<210> 83
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 83
ctgtaggcag aaaagggaa                                                    19


<210> 84
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 84
cactcttcgg gagaatacag                                                   20


<210> 85
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 85
catttggtac aagcaaggtg                                                   20


<210> 86
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 86
gaaggatgtg gtccgagtgt                                                   20


<210> 87
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 87
gtgaagtgag ggctcccata                                                   20


<210> 88
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 88
acaagtggcc aattcactcc                                                   20


<210> 89
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 89
gaggtggaca agggatctga                                                   20


<210> 90
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 90
acccattatc cagatgtgtt tgcccgag                                          28


<210> 91
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 91
atggtgaagc tgggcatagg cggcag                                            26


<210> 92
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 92
ggaaccgcta ccccgacatg ag                                                22


<210> 93
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 93
tgaaggcgaa tggaaaggtc t                                                 21


<210> 94
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 94
ggcggaaata gaacctgtca                                                   20


<210> 95
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 95
cttccaggat gggttgagaa                                                   20


<210> 96
<211> 17
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 96
cctccgtcca tcctctg                                                      17


<210> 97
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 97
aagcatcaaa caacctcaag                                                   20


<210> 98
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 98
aaccccaaga tgcacaactc                                                   20


<210> 99
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 99
cggggccggt atttataatc                                                   20


<210> 100
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 100
cgctttcatg gtgtgggcta aggacg                                            26


<210> 101
<211> 26
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 101
tagttggggt ggtcctgcat gtgctg                                            26


<210> 102
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 102
cgggcttctc ggaccaggtg ta                                                22


<210> 103
<211> 22
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 103
ctcctcggcg gtgtactcca ca                                                22


<210> 104
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 104
cggtggtgga gccctacaac                                                   20


<210> 105
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 105
aggtggtgac tccgctcat                                                    19


<210> 106
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 106
attgccccaa aacttttttg                                                   20


<210> 107
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 107
ccacatctcc ctccagaaaa                                                   20


<210> 108
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 108
agggtctggg ccatagaact                                                   20


<210> 109
<211> 20
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      primer

<400> 109
ttgaagacca gtctgggaag                                                   20


