                         SEQUENCE LISTING

<110>  WAVE LIFE SCIENCES LTD.
 
<120>  OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF

<130>  2010581-0795

<140>  PCT/US2020/032244
<141>  2020-05-08

<150>  US 62/845,765
<151>  2019-05-09

<150>  US 62/851,558
<151>  2019-05-22

<150>  US 62/911,340
<151>  2019-10-06

<150>  US 62/983,736
<151>  2020-03-01

<160>  550   

<170>  PatentIn version 3.5

<210>  1
<211>  3000
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 30 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 50 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 100 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 150 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 200 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 300 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 500 times or more.

<400>  1
ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc       60

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3000


<210>  2
<211>  180
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  2
ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc       60

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      180


<210>  3
<211>  21
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  3
gcauagcgag cgagggaaaa c                                                 21


<210>  4
<211>  21
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  4
guuuucccuc gcucgcuaug c                                                 21


<210>  5
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  5
cccacacctg ctcttgctag                                                   20


<210>  6
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  6
aacagccacc cgccaggatg                                                   20


<210>  7
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  7
aaccgggcag cagggacggc                                                   20


<210>  8
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  8
acaggctgcg gttgtttccc                                                   20


<210>  9
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  9
acccacacct gctcttgcta                                                   20


<210>  10
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  10
acccactcgc caccgcctgc                                                   20


<210>  11
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  11
accccaaaca gccacccgcc                                                   20


<210>  12
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  12
acccccatct catcccgcat                                                   20


<210>  13
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  13
acccgagctg tctccttccc                                                   20


<210>  14
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  14
acccgccagg atgccgcctc                                                   20


<210>  15
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  15
acccgcgcct cttcccggca                                                   20


<210>  16
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  16
accctccggc cttcccccag                                                   20


<210>  17
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  17
accgggcagc agggacggct                                                   20


<210>  18
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  18
acctctcttt cctagcggga                                                   20


<210>  19
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  19
acgcacctct ctttcctagc                                                   20


<210>  20
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  20
actcacccac tcgccaccgc                                                   20


<210>  21
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  21
agcaaccggg cagcagggac                                                   20


<210>  22
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  22
agccgtccct gctgcccggt                                                   20


<210>  23
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  23
agcgcgcgac tcctgagttc                                                   20


<210>  24
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  24
agcttgctac aggctgcggt                                                   20


<210>  25
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  25
aggatgccgc ctcctcactc                                                   20


<210>  26
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  26
aggctgcggt tgtttccctc                                                   20


<210>  27
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  27
aggctgtcag ctcggatctc                                                   20


<210>  28
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  28
agggccaccc ctcctgggaa                                                   20


<210>  29
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  29
atcccctcac aggctcttgt                                                   20


<210>  30
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  30
atgccgcctc ctcactcacc                                                   20


<210>  31
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  31
attgcctgca tccgggcccc                                                   20


<210>  32
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  32
cacccactcg ccaccgcctg                                                   20


<210>  33
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  33
cacccccatc tcatcccgca                                                   20


<210>  34
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  34
cacccgccag gatgccgcct                                                   20


<210>  35
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  35
cacctctctt tcctagcggg                                                   20


<210>  36
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  36
cactcaccca ctcgccaccg                                                   20


<210>  37
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  37
caggatgccg cctcctcact                                                   20


<210>  38
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  38
caggctgcgg ttgtttccct                                                   20


<210>  39
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  39
cagggtggca tctgcttcac                                                   20


<210>  40
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  40
ccaaacagcc acccgccagg                                                   20


<210>  41
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  41
ccacccgcca ggatgccgcc                                                   20


<210>  42
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  42
ccaccctccg gccttccccc                                                   20


<210>  43
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  43
ccactcgcca ccgcctgcgc                                                   20


<210>  44
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  44
ccaggatgcc gcctcctcac                                                   20


<210>  45
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  45
cccaaacagc cacccgccag                                                   20


<210>  46
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  46
cccactcgcc accgcctgcg                                                   20


<210>  47
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  47
ccccaaacag ccacccgcca                                                   20


<210>  48
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  48
cccgccagga tgccgcctcc                                                   20


<210>  49
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  49
cctcactcac ccactcgccg                                                   20


<210>  50
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  50
cccgcgcctc ttcccggcag                                                   20


<210>  51
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  51
cccggcagcc gaaccccaaa                                                   20


<210>  52
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  52
ccgacttgca ttgctgccct                                                   20


<210>  53
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  53
ccgcagcctg tagcaagctc                                                   20


<210>  54
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  54
ccgccaggat gccgcctcct                                                   20


<210>  55
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  55
ccgcctcctc actcacccac                                                   20


<210>  56
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  56
ccgcgcctct tcccggcagc                                                   20


<210>  57
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  57
ccgcttctac ccgcgcctct                                                   20


<210>  58
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  58
ccgggcagca gggacggctg                                                   20


<210>  59
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  59
cctagcggga caccgtaggt                                                   20


<210>  60
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  60
cctcactcac ccactcgcca                                                   20


<210>  61
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  61
cctccggcct tcccccaggc                                                   20


<210>  62
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  62
cctcctcact cacccactcg                                                   20


<210>  63
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  63
cctctctttc ctagcgggac                                                   20


<210>  64
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  64
cctctgccaa ggcctgccac                                                   20


<210>  65
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  65
cctcttcccg gcagccgaac                                                   20


<210>  66
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  66
cctgagttcc agagcttgct                                                   20


<210>  67
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  67
cctgctcttg ctagaccccg                                                   20


<210>  68
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  68
cctgctgccc ggttgcttct                                                   20


<210>  69
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  69
cctggttgct tcacagctcc                                                   20


<210>  70
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  70
ccttccctga aggttcctcc                                                   20


<210>  71
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  71
cgcacctctc tttcctagcg                                                   20


<210>  72
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  72
cgcatagaat ccagtaccat                                                   20


<210>  73
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  73
cgccaggatg ccgcctcctc                                                   20


<210>  74
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  74
cgcctcctca ctcacccact                                                   20


<210>  75
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  75
cgcctcttcc cggcagccga                                                   20


<210>  76
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  76
cgcgcgactc ctgagttcca                                                   20


<210>  77
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  77
cgcttctacc cgcgcctctt                                                   20


<210>  78
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  78
cgggcagcag ggacggctga                                                   20


<210>  79
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  79
cggttgtttc cctccttgtt                                                   20


<210>  80
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  80
ctacccgcgc ctcttcccgg                                                   20


<210>  81
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  81
ctcacccact cgccaccgcc                                                   20


<210>  82
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  82
ctcactcacc cactcgccac                                                   20


<210>  83
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  83
ctcagtaccc gaggctccct                                                   20


<210>  84
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  84
ctcctcactc acccactcgc                                                   20


<210>  85
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  85
ctcttcccgg cagccgaacc                                                   20


<210>  86
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  86
ctcttgctag accccgcccc                                                   20


<210>  87
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  87
ctctttccta gcgggacacc                                                   20


<210>  88
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  88
ctgcggttgt ttccctcctt                                                   20


<210>  89
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  89
ctgctcttgc tagaccccgc                                                   20


<210>  90
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  90
cttcccggca gccgaacccc                                                   20


<210>  91
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  91
cttccttgct ttcccgccct                                                   20


<210>  92
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  92
cttctacccg cgcctcttcc                                                   20


<210>  93
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  93
cttgctagac cccgccccca                                                   20


<210>  94
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  94
cttggtgtgt cagccgtccc                                                   20


<210>  95
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  95
cttgttcacc ctcagcgagt                                                   20


<210>  96
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  96
ctttcctagc gggacaccgt                                                   20


<210>  97
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  97
gacatcccct cacaggctct                                                   20


<210>  98
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  98
gagagccccc gcttctaccc                                                   20


<210>  99
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  99
gagctgccca ggaccacttc                                                   20


<210>  100
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  100
gagcttgcta caggctgcgg                                                   20


<210>  101
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  101
gaggccagat ccccatccct                                                   20


<210>  102
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  102
gatccccatt ccagtttcca                                                   20


<210>  103
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  103
gatgccgcct cctcactcac                                                   20


<210>  104
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  104
gcaaccgggc agcagggacg                                                   20


<210>  105
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  105
gcacctctct ttcctagcgg                                                   20


<210>  106
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  106
gcaggcggtg gcgagtgggt                                                   20


<210>  107
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  107
gcaggcgtct ccacaccccc                                                   20


<210>  108
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  108
gcagggacgg ctgacacacc                                                   20


<210>  109
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  109
gcatccgggc cccgggcttc                                                   20


<210>  110
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  110
gcatcctggc gggtggctgt                                                   20


<210>  111
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  111
gccacccgcc aggatgccgc                                                   20


<210>  112
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  112
gccagatccc catcccttgt                                                   20


<210>  113
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  113
gccaggatgc cgcctcctca                                                   20


<210>  114
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  114
gccctcagta cccgagctgt                                                   20


<210>  115
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  115
gccgcctcct cactcaccca                                                   20


<210>  116
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  116
gccgggaaga ggcgcgggta g                                                 21


<210>  117
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  117
gccgtccctg ctgcccggtt                                                   20


<210>  118
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  118
gcctcctcac tcacccactc                                                   20


<210>  119
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  119
gcctctcagt acccgaggct                                                   20


<210>  120
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  120
gcctcttccc ggcagccgaa                                                   20


<210>  121
<211>  40
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  121
gcgcaggcgg tggcgagtgg gtgagtgagg aggcggcatc                             40


<210>  122
<211>  30
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  122
gcgcaggcgg tggcgagtgg gtgagtgagg                                        30


<210>  123
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  123
gcgcgactcc tgagttccag                                                   20


<210>  124
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  124
gcgcgcgact cctgagttcc                                                   20


<210>  125
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  125
gcggcatcct ggcgggtggc                                                   20


<210>  126
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  126
gcggttgcgg tgcctgcgcc                                                   20


<210>  127
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  127
gcggttgttt ccctccttgt                                                   20


<210>  128
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  128
gctacaggct gcggttgttt                                                   20


<210>  129
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  129
gctagacccc gcccccaaaa                                                   20


<210>  130
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  130
gctctgagga gagcccccgc                                                   20


<210>  131
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  131
gctcttgcta gaccccgccc                                                   20


<210>  132
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  132
gctgcgatcc ccattccagt                                                   20


<210>  133
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  133
gctgcggttg tttccctcct                                                   20


<210>  134
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  134
gctggagatg gcggtgggca                                                   20


<210>  135
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  135
gctgggtgtc gggctttcgc                                                   20


<210>  136
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  136
gctgtttgac gcacctctct                                                   20


<210>  137
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  137
gcttctaccc gcgcctcttc                                                   20


<210>  138
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  138
gcttgctaca ggctgcggtt                                                   20


<210>  139
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  139
gcttggtgtg tcagccgtcc                                                   20


<210>  140
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  140
gctttcccgc cctcagtacc                                                   20


<210>  141
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  141
ggacccgctg ggagcgctgc                                                   20


<210>  142
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  142
ggatgccgcc tcctcactca                                                   20


<210>  143
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  143
ggcagcaggg acggctgaca                                                   20


<210>  144
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  144
ggcctctcag tacccgaggc                                                   20


<210>  145
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  145
ggcggaggcg caggcggtgg                                                   20


<210>  146
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  146
ggcgtctcca cacccccatc                                                   20


<210>  147
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  147
ggctcccttt tctcgagccc                                                   20


<210>  148
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  148
ggctgcggtt gtttccctcc                                                   20


<210>  149
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  149
gggaaggccg gagggtgggc                                                   20


<210>  150
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  150
gggcagcagg gacggctgac                                                   20


<210>  151
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  151
gggctctcct cagagctcga                                                   20


<210>  152
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  152
gggtgtcggg ctttcgcctc                                                   20


<210>  153
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  153
ggtccctgcc ggcgaggaga                                                   20


<210>  154
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  154
gtacccgagg ctcccttttc                                                   20


<210>  155
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  155
gtcagccgtc cctgctgccc                                                   20


<210>  156
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  156
gtccctgctg cccggttgct                                                   20


<210>  157
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  157
gtccgtgtgc tcattgggtc                                                   20


<210>  158
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  158
gtcgctgttt gacgcacctc                                                   20


<210>  159
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  159
gtcggtgtgc tccccattct                                                   20


<210>  160
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  160
gtgcaggcgt ctccacaccc                                                   20


<210>  161
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  161
gtgctgcgat ccccattcca                                                   20


<210>  162
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  162
gtggcaggcc ttggcagagg                                                   20


<210>  163
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  163
gttcaccctc agcgagtact                                                   20


<210>  164
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  164
gttgcggtgc ctgcgcccgc                                                   20


<210>  165
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  165
gttgtttccc tccttgtttt                                                   20


<210>  166
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  166
tacaggctgc ggttgtttcc                                                   20


<210>  167
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  167
tacccgcgcc tcttcccggc                                                   20


<210>  168
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  168
tcacccactc gccaccgcct                                                   20


<210>  169
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  169
tcaccctcag cgagtactgt                                                   20


<210>  170
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  170
tcactcaccc actcgccacc                                                   20


<210>  171
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  171
tcccctcaca ggctcttgtg                                                   20


<210>  172
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  172
tcccggcagc cgaaccccaa                                                   20


<210>  173
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  173
tcctcactca cccactcgcc                                                   20


<210>  174
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  174
tccttgcttt cccgccctca                                                   20


<210>  175
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  175
tctcagtacc cgaggctccc                                                   20


<210>  176
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  176
tcttcccggc agccgaaccc                                                   20


<210>  177
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  177
tcttgctaga ccccgccccc                                                   20


<210>  178
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  178
tgccgcctcc tcactcaccc                                                   20


<210>  179
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  179
tgcctgcatc cgggccccgg                                                   20


<210>  180
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  180
tgcggttgtt tccctccttg                                                   20


<210>  181
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  181
tgctacaggc tgcggttgtt                                                   20


<210>  182
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  182
tgctagaccc cgcccccaaa                                                   20


<210>  183
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  183
tgctcttgct agaccccgcc                                                   20


<210>  184
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  184
tggaatgggg atcgcagcac                                                   20


<210>  185
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  185
tggaatgggg atcgcagcac a                                                 21


<210>  186
<211>  30
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  186
tggcgagtgg gtgagtgagg aggcggcatc                                        30


<210>  187
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  187
tgtgctgcga tccccattcc                                                   20


<210>  188
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  188
ttccagagct tgctacaggc                                                   20


<210>  189
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  189
ttcccggcag ccgaacccca                                                   20


<210>  190
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  190
ttctacccgc gcctcttccc                                                   20


<210>  191
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  191
ttgctacagg ctgcggttgt                                                   20


<210>  192
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  192
ttgctagacc ccgcccccaa                                                   20


<210>  193
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  193
tttccccaca ccactgagct                                                   20


<210>  194
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  194
acccactcgc ca                                                           12


<210>  195
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  195
acccactcgc ca                                                           12


<210>  196
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  196
actcacccac tcgccaccgc                                                   20


<210>  197
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  197
actcacccac tcgccaccgc                                                   20


<210>  198
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  198
actcacccac tcgccaccgc                                                   20


<210>  199
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  199
actcacccac tcgccaccgc                                                   20


<210>  200
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  200
actcacccac tcgccaccgc                                                   20


<210>  201
<211>  8
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  201
actcgcca                                                                 8


<210>  202
<211>  12
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  202
auacuuaccu gg                                                           12


<210>  203
<211>  9
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  203
cactcgcca                                                                9


<210>  204
<211>  11
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  204
cccactcgcc a                                                            11


<210>  205
<211>  11
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  205
cccactcgcc a                                                            11


<210>  206
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  206
cctcactcac ccactcgcc                                                    19


<210>  207
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  207
cctcactcac ccactcgcc                                                    19


<210>  208
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  208
cctcactcac ccactcgcca                                                   20


<210>  209
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  209
cctcactcac ccactcgcca                                                   20


<210>  210
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  210
cctcactcac ccactcgcca                                                   20


<210>  211
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  211
cctcactcac ccactcgcca                                                   20


<210>  212
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  212
cctcactcac ccactcgcca                                                   20


<210>  213
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  213
cctcactcac ccactcgcca                                                   20


<210>  214
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  214
cctcactcac ccactcgcca                                                   20


<210>  215
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  215
cctcactcac ccactcgcca                                                   20


<210>  216
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  216
cctcactcac ccactcgccc                                                   20


<210>  217
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  217
cctcactcac ccactcgccc                                                   20


<210>  218
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  218
cctcactcac ccactcgccg                                                   20


<210>  219
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  219
cctcactcac ccactcgccg                                                   20


<210>  220
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  220
cctcactcac ccactcgccg                                                   20


<210>  221
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  221
cctcactcac ccactcgccg                                                   20


<210>  222
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  222
cctcactcac ccactcgccg                                                   20


<210>  223
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  223
cctcactcac ccactcgccg                                                   20


<210>  224
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is inosine

<400>  224
cctcactcac ccactcgccn                                                   20


<210>  225
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is inosine

<400>  225
cctcactcac ccactcgccn                                                   20


<210>  226
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  226
cctcactcac ccactcgccu                                                   20


<210>  227
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  227
cctcactcac ccactcgccu                                                   20


<210>  228
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  228
cctcactcac ccacucgcc                                                    19


<210>  229
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  229
cctcactcac ccacucgcc                                                    19


<210>  230
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  230
cctcactcac ccacucgcc                                                    19


<210>  231
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  231
cctcactcac ccacucgcca                                                   20


<210>  232
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  232
cctgctgccc ggttgcttct                                                   20


<210>  233
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  233
cctgctgccc ggttgcuucu                                                   20


<210>  234
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  234
ccugctgccc ggttgcttct                                                   20


<210>  235
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  235
cgccucctca ctcacccacu                                                   20


<210>  236
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  236
ctcactcacc cactcgccac                                                   20


<210>  237
<211>  24
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  237
cucuggaacu caggagucgc gcgc                                              24


<210>  238
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  238
gcgcgactcc tgagttccag                                                   20


<210>  239
<211>  12
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  239
gcuaccuaua ug                                                           12


<210>  240
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  240
gtccctgctg cccggttgct                                                   20


<210>  241
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  241
guccctgctg cccggttgct                                                   20


<210>  242
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  242
tccttgcttt cccgccctca                                                   20


<210>  243
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  243
tgccgcctcc tcactcaccc                                                   20


<210>  244
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  244
ucctcactca cccacucgcc                                                   20


<210>  245
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U; and any U, if present, can be independently 
       and optionally substituted with T

<220>
<221>  misc_feature
<223>  any C and/or G in one or more CpG motifs, if present, is replaced
       by another base; and in some embodiments, the G nucleobase in a 
       CpG motif is replaced by I

<400>  245
uccutgcttt cccgccctca                                                   20


<210>  246
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  246
actcacccac tcgccaccgc                                                   20


<210>  247
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  247
actcacccac tcgccaccgc                                                   20


<210>  248
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  248
actcacccac tcgccaccgc                                                   20


<210>  249
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  249
actcacccac tcgccaccgc                                                   20


<210>  250
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  250
cctcactcac ccactcgcca                                                   20


<210>  251
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  251
cctcactcac ccactcgcca                                                   20


<210>  252
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  252
atacttacct gg                                                           12


<210>  253
<211>  9
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  253
cactcgcca                                                                9


<210>  254
<211>  8
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  254
actcgcca                                                                 8


<210>  255
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  255
acccactcgc ca                                                           12


<210>  256
<211>  11
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  256
cccactcgcc a                                                            11


<210>  257
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  257
tgccgcctcc tcactcaccc                                                   20


<210>  258
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  258
tgccgcctcc tcactcaccc                                                   20


<210>  259
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  259
gcgcgactcc tgagttccag                                                   20


<210>  260
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  260
tccttgcttt cccgccctca                                                   20


<210>  261
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  261
tccttgcttt cccgccctca                                                   20


<210>  262
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  262
tccttgcttt cccgccctca                                                   20


<210>  263
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  263
gtccctgctg cccggttgct                                                   20


<210>  264
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  264
gtccctgctg cccggttgct                                                   20


<210>  265
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  265
gtccctgctg cccggttgct                                                   20


<210>  266
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  266
cctgctgccc ggttgcttct                                                   20


<210>  267
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  267
cctgctgccc ggttgcttct                                                   20


<210>  268
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  268
cctgctgccc ggttgcttct                                                   20


<210>  269
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  269
gctacctata tg                                                           12


<210>  270
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  270
ctctggaact caggagtcgc gcgc                                              24


<210>  271
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is inosine

<400>  271
cctcactcac ccactcgccn                                                   20


<210>  272
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  272
cctcactcac ccactcgccg                                                   20


<210>  273
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  273
tcctcactca cccactcgcc                                                   20


<210>  274
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  274
ctcactcacc cactcgccac                                                   20


<210>  275
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  275
actcacccac tcgccaccgc                                                   20


<210>  276
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  276
cgcctcctca ctcacccact                                                   20


<210>  277
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  277
cctcactcac ccactcgcc                                                    19


<210>  278
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  278
cctcactcac ccactcgcca                                                   20


<210>  279
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  279
cctcactcac ccactcgcc                                                    19


<210>  280
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  280
cctcactcac ccactcgccc                                                   20


<210>  281
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  any T, if present, can be independently and optionally 
       substituted with U

<400>  281
cctcactcac ccactcgcct                                                   20


<210>  282
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  282
cctcactcac ccactcgcca                                                   20


<210>  283
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  283
cctcactcac ccactcgcca                                                   20


<210>  284
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  284
cctcactcac ccactcgcca                                                   20


<210>  285
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  285
cctcactcac ccactcgcca                                                   20


<210>  286
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  286
cctcactcac ccactcgcca                                                   20


<210>  287
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  287
ccucactcac ccactcgcca                                                   20


<210>  288
<211>  12
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  288
auacuuaccu gg                                                           12


<210>  289
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  289
cctcactcac ccactcgcca                                                   20


<210>  290
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  290
cctcactcac ccactcgcca                                                   20


<210>  291
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  291
cctcactcac ccactcgcca                                                   20


<210>  292
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  292
cctcactcac ccactcgcca                                                   20


<210>  293
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  293
cctcactcac ccactcgcca                                                   20


<210>  294
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  294
cctcactcac ccactcgcca                                                   20


<210>  295
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  295
cctcactcac ccactcgcca                                                   20


<210>  296
<211>  9
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  296
cactcgcca                                                                9


<210>  297
<211>  8
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  297
actcgcca                                                                 8


<210>  298
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  298
cctcactcac ccactcgcca                                                   20


<210>  299
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  299
cctcactcac ccactcgcca                                                   20


<210>  300
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  300
cctcactcac ccactcgcca                                                   20


<210>  301
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  301
acccactcgc ca                                                           12


<210>  302
<211>  11
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  302
cccactcgcc a                                                            11


<210>  303
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  303
acccactcgc ca                                                           12


<210>  304
<211>  11
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  304
cccactcgcc a                                                            11


<210>  305
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  305
tgccgcctcc tcactcaccc                                                   20


<210>  306
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  306
tgccgcctcc tcactcaccc                                                   20


<210>  307
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  307
tgccgcctcc tcactcaccc                                                   20


<210>  308
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  308
tgccgcctcc tcactcaccc                                                   20


<210>  309
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  309
tgccgcctcc tcactcaccc                                                   20


<210>  310
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  310
ugccgcctcc tcactcaccc                                                   20


<210>  311
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  311
gcgcgactcc tgagttccag                                                   20


<210>  312
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  312
gcgcgactcc tgagttccag                                                   20


<210>  313
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  313
gcgcgactcc tgagttccag                                                   20


<210>  314
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  314
gcgcgactcc tgagttccag                                                   20


<210>  315
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  315
gcgcgactcc tgagttccag                                                   20


<210>  316
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  316
gcgcgactcc tgagttccag                                                   20


<210>  317
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  317
tccttgcttt cccgccctca                                                   20


<210>  318
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  318
tccttgcttt cccgccctca                                                   20


<210>  319
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  319
tccttgcttt cccgccctca                                                   20


<210>  320
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  320
tccttgcttt cccgccctca                                                   20


<210>  321
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  321
tccttgcttt cccgcccuca                                                   20


<210>  322
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  322
uccutgcttt cccgccctca                                                   20


<210>  323
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  323
gtccctgctg cccggttgct                                                   20


<210>  324
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  324
gtccctgctg cccggttgct                                                   20


<210>  325
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  325
gtccctgctg cccggttgct                                                   20


<210>  326
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  326
gtccctgctg cccggttgct                                                   20


<210>  327
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  327
gtccctgctg cccgguugcu                                                   20


<210>  328
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  328
guccctgctg cccggttgct                                                   20


<210>  329
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  329
cctgctgccc ggttgcttct                                                   20


<210>  330
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  330
cctgctgccc ggttgcttct                                                   20


<210>  331
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  331
cctgctgccc ggttgcttct                                                   20


<210>  332
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  332
cctgctgccc ggttgcttct                                                   20


<210>  333
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  333
cctgctgccc ggttgcuucu                                                   20


<210>  334
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  334
ccugctgccc ggttgcttct                                                   20


<210>  335
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  335
cctcactcac ccactcgcca                                                   20


<210>  336
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  336
cctcactcac ccactcgcca                                                   20


<210>  337
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  337
cctcactcac ccactcgcca                                                   20


<210>  338
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  338
cctcactcac ccactcgcca                                                   20


<210>  339
<211>  12
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  339
gcuaccuaua ug                                                           12


<210>  340
<211>  24
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  340
cucuggaacu caggagucgc gcgc                                              24


<210>  341
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  341
cctcactcac ccactcgcca                                                   20


<210>  342
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  342
cctcactcac ccactcgcca                                                   20


<210>  343
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  343
cctcactcac ccactcgcca                                                   20


<210>  344
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is inosine

<400>  344
cctcactcac ccactcgccn                                                   20


<210>  345
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  345
cctcactcac ccactcgccg                                                   20


<210>  346
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<222>  (20)..(20)
<223>  n is inosine

<400>  346
cctcactcac ccactcgccn                                                   20


<210>  347
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  347
cctcactcac ccactcgccg                                                   20


<210>  348
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  348
cctcactcac ccactcgcca                                                   20


<210>  349
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  349
cctcactcac ccactcgcca                                                   20


<210>  350
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  350
cctcactcac ccactcgcca                                                   20


<210>  351
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  351
ucctcactca cccacucgcc                                                   20


<210>  352
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  352
ucctcactca cccacucgcc                                                   20


<210>  353
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  353
ucctcactca cccacucgcc                                                   20


<210>  354
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  354
ucctcactca cccacucgcc                                                   20


<210>  355
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  355
ucctcactca cccacucgcc                                                   20


<210>  356
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  356
ucctcactca cccacucgcc                                                   20


<210>  357
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  357
ctcactcacc cactcgccac                                                   20


<210>  358
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  358
ctcactcacc cactcgccac                                                   20


<210>  359
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  359
ctcactcacc cactcgccac                                                   20


<210>  360
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  360
ctcactcacc cactcgccac                                                   20


<210>  361
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  361
ctcactcacc cactcgccac                                                   20


<210>  362
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  362
ctcactcacc cactcgccac                                                   20


<210>  363
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  363
actcacccac tcgccaccgc                                                   20


<210>  364
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  364
actcacccac tcgccaccgc                                                   20


<210>  365
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  365
actcacccac tcgccaccgc                                                   20


<210>  366
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  366
cgccucctca ctcacccacu                                                   20


<210>  367
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  367
cgccucctca ctcacccacu                                                   20


<210>  368
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  368
cgccucctca ctcacccacu                                                   20


<210>  369
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  369
cctcactcac ccactcgcca                                                   20


<210>  370
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  370
cctcactcac ccactcgcca                                                   20


<210>  371
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  371
cctcactcac ccacucgcc                                                    19


<210>  372
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  372
cctcactcac ccacucgcc                                                    19


<210>  373
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  373
cctcactcac ccacucgcc                                                    19


<210>  374
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  374
cctcactcac ccacucgcc                                                    19


<210>  375
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  375
cctcactcac ccacucgcca                                                   20


<210>  376
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  376
cctcactcac ccacucgcca                                                   20


<210>  377
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  377
cctcactcac ccacucgcca                                                   20


<210>  378
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  378
cctcactcac ccacucgcca                                                   20


<210>  379
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  379
cctcactcac ccacucgcca                                                   20


<210>  380
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  380
cctcactcac ccacucgcca                                                   20


<210>  381
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  381
cctcactcac ccactcgcca                                                   20


<210>  382
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  382
cctcactcac ccacucgcca                                                   20


<210>  383
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  383
cctcactcac ccacucgcca                                                   20


<210>  384
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  384
cctcactcac ccacucgcca                                                   20


<210>  385
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  385
cctcactcac ccacucgcca                                                   20


<210>  386
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  386
cctcactcac ccacucgcca                                                   20


<210>  387
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  387
cctcactcac ccacucgcca                                                   20


<210>  388
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  388
cctcactcac ccacucgcc                                                    19


<210>  389
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  389
cctcactcac ccacucgcc                                                    19


<210>  390
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  390
cctcactcac ccacucgcc                                                    19


<210>  391
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  391
cctcactcac ccacucgcc                                                    19


<210>  392
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  392
cctcactcac ccacucgcc                                                    19


<210>  393
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  393
cctcactcac ccactcgcca                                                   20


<210>  394
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  394
cctcactcac ccactcgcca                                                   20


<210>  395
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  395
cctcactcac ccactcgcca                                                   20


<210>  396
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  396
cctcactcac ccactcgcca                                                   20


<210>  397
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  397
cctcactcac ccactcgcca                                                   20


<210>  398
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  398
actcacccac tcgccaccgc                                                   20


<210>  399
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  399
actcacccac tcgccaccgc                                                   20


<210>  400
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  400
actcacccac tcgccaccgc                                                   20


<210>  401
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  401
actcacccac tcgccaccgc                                                   20


<210>  402
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  402
actcacccac tcgccaccgc                                                   20


<210>  403
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  403
actcacccac tcgccaccgc                                                   20


<210>  404
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  404
actcacccac tcgccaccgc                                                   20


<210>  405
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  405
actcacccac tcgccaccgc                                                   20


<210>  406
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  406
actcacccac tcgccaccgc                                                   20


<210>  407
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  407
actcacccac tcgccaccgc                                                   20


<210>  408
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  408
cctcactcac ccactcgcc                                                    19


<210>  409
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  409
cctcactcac ccactcgcc                                                    19


<210>  410
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  410
cctcactcac ccactcgcc                                                    19


<210>  411
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  411
cctcactcac ccactcgcc                                                    19


<210>  412
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  412
cctcactcac ccactcgcc                                                    19


<210>  413
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  413
cctcactcac ccactcgccg                                                   20


<210>  414
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  414
cctcactcac ccactcgccg                                                   20


<210>  415
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  415
cctcactcac ccactcgccg                                                   20


<210>  416
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  416
cctcactcac ccactcgccg                                                   20


<210>  417
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  417
actcacccac tcgccaccgc                                                   20


<210>  418
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  418
actcacccac tcgccaccgc                                                   20


<210>  419
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  419
actcacccac tcgccaccgc                                                   20


<210>  420
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  420
actcacccac tcgccaccgc                                                   20


<210>  421
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  421
cctcactcac ccactcgccg                                                   20


<210>  422
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  422
cctcactcac ccactcgcc                                                    19


<210>  423
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  423
cctcactcac ccactcgccg                                                   20


<210>  424
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  424
cctcactcac ccactcgccg                                                   20


<210>  425
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  425
cctcactcac ccactcgccg                                                   20


<210>  426
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  426
actcacccac tcgccaccgc                                                   20


<210>  427
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  427
actcacccac tcgccaccgc                                                   20


<210>  428
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  428
actcacccac tcgccaccgc                                                   20


<210>  429
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  429
cctcactcac ccactcgccc                                                   20


<210>  430
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  430
cctcactcac ccactcgccc                                                   20


<210>  431
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  431
cctcactcac ccactcgccu                                                   20


<210>  432
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  432
cctcactcac ccactcgccu                                                   20


<210>  433
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  433
cctcactcac ccactcgccg                                                   20


<210>  434
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  434
cctcactcac ccactcgccg                                                   20


<210>  435
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  435
cctcactcac ccactcgccg                                                   20


<210>  436
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  436
cctcactcac ccactcgccg                                                   20


<210>  437
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  437
cctcactcac ccactcgccg                                                   20


<210>  438
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  438
cctcactcac ccactcgccg                                                   20


<210>  439
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  439
cctcactcac ccactcgccg                                                   20


<210>  440
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  440
cctcactcac ccactcgccg                                                   20


<210>  441
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  441
cctcactcac ccactcgccg                                                   20


<210>  442
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  442
cctcactcac ccactcgccg                                                   20


<210>  443
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  443
cctcactcac ccactcgccg                                                   20


<210>  444
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  444
cctcactcac ccactcgccg                                                   20


<210>  445
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  445
cctcactcac ccactcgccg                                                   20


<210>  446
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  446
cctcactcac ccactcgccg                                                   20


<210>  447
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  447
cctcactcac ccactcgccc                                                   20


<210>  448
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  448
cctcactcac ccactcgccc                                                   20


<210>  449
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  449
cctcactcac ccactcgccu                                                   20


<210>  450
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  450
cctcactcac ccactcgccu                                                   20


<210>  451
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  451
cctcactcac ccactugccg                                                   20


<210>  452
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  452
cctcactcac ccactcgcug                                                   20


<210>  453
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  453
cctcactcac ccactugcug                                                   20


<210>  454
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  454
cctcactcac ccactugcc                                                    19


<210>  455
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  455
actcacccac ttgccaccgc                                                   20


<210>  456
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  456
actcacccac tcgccacugc                                                   20


<210>  457
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  457
actcacccac ttgccacugc                                                   20


<210>  458
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  458
actcacccac ttgccaccgc                                                   20


<210>  459
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  459
actcacccac tcgccacugc                                                   20


<210>  460
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  460
actcacccac ttgccacugc                                                   20


<210>  461
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  461
actcacccac ttgccaccgc                                                   20


<210>  462
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  462
actcacccac tcgccacugc                                                   20


<210>  463
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  463
actcacccac ttgccacugc                                                   20


<210>  464
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  464
actcacccac ttgccaccgc                                                   20


<210>  465
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  465
actcacccac tcgccacugc                                                   20


<210>  466
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  466
actcacccac ttgccacugc                                                   20


<210>  467
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  467
actcacccac ttgccaccgc                                                   20


<210>  468
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  468
actcacccac ttgccaccgc                                                   20


<210>  469
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  469
actcacccac ttgccaccgc                                                   20


<210>  470
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  470
actcacccac ttgccaccgc                                                   20


<210>  471
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  471
actcacccac ttgccaccgc                                                   20


<210>  472
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  472
actcacccac ttgccaccgc                                                   20


<210>  473
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  473
cctcactcac ccactugcca                                                   20


<210>  474
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  474
cctcactcac ccactugcca                                                   20


<210>  475
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  475
cctcactcac ccactcgcua                                                   20


<210>  476
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  476
cctcactcac ccactugcua                                                   20


<210>  477
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  477
cctcactcac ccactcgccg                                                   20


<210>  478
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  478
cctcactcac ccactcgcc                                                    19


<210>  479
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  479
cctcactcac ccactcgcc                                                    19


<210>  480
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  480
cctcactcac ccactugcug                                                   20


<210>  481
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  481
cctcactcac ccactcgcca                                                   20


<210>  482
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  482
cctcactcac ccactcgccg                                                   20


<210>  483
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  483
cctcactcac ccactcgcca                                                   20


<210>  484
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  484
cctcactcac ccactcgccg                                                   20


<210>  485
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  485
cctcactcac ccactcgcca                                                   20


<210>  486
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  486
cctcactcac ccactcgccg                                                   20


<210>  487
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  487
actcacccac tcgccaccgc                                                   20


<210>  488
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  488
actcacccac tcgccaccgc                                                   20


<210>  489
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  489
actcacccac tcgccaccgc                                                   20


<210>  490
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  490
actcacccac tcgccaccgc                                                   20


<210>  491
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  491
actcacccac tcgccaccgc                                                   20


<210>  492
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  492
actcacccac tcgccaccgc                                                   20


<210>  493
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  493
actcacccac tcgccaccgc                                                   20


<210>  494
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  494
actcacccac tcgccacugc                                                   20


<210>  495
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  495
actcacccac tcgccacugc                                                   20


<210>  496
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  496
actcacccac tcgccacugc                                                   20


<210>  497
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  497
actcacccac tcgccacugc                                                   20


<210>  498
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  498
actcacccac tcgccacugc                                                   20


<210>  499
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  499
cctcactcac ccactcgccg                                                   20


<210>  500
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  500
cctcactcac ccactcgccg                                                   20


<210>  501
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  501
cctcactcac ccactcgccg                                                   20


<210>  502
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  502
cctcactcac ccactcgccg                                                   20


<210>  503
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  503
cctcactcac ccactcgccg                                                   20


<210>  504
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  504
cctcactcac ccactcgccg                                                   20


<210>  505
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  505
cctcactcac ccactcgccg                                                   20


<210>  506
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  506
cctcactcac ccactugcug                                                   20


<210>  507
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  507
ccucactcac ccacttgctg                                                   20


<210>  508
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  508
cctcactcac ccacttgctg                                                   20


<210>  509
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  509
cctcactcac ccactugcug                                                   20


<210>  510
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  510
ccucactcac ccacttgctg                                                   20


<210>  511
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  511
cctcactcac ccacttgctg                                                   20


<210>  512
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  512
cctcactcac ccacttgctg                                                   20


<210>  513
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  513
actcacccac tcgccacugc                                                   20


<210>  514
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  514
cctcactcac ccacttgcca                                                   20


<210>  515
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  515
cctcactcac ccacttgcc                                                    19


<210>  516
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  516
actcacccac tcgccactgc                                                   20


<210>  517
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  517
actcacccac tcgccaccgc                                                   20


<210>  518
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  518
actcacccac tcgccaccgc                                                   20


<210>  519
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  519
actcacccac tcgccaccgc                                                   20


<210>  520
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  520
actcacccac tcgccaccgc                                                   20


<210>  521
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  521
actcacccac tcgccaccgc                                                   20


<210>  522
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  522
actcacccac tcgccaccgc                                                   20


<210>  523
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  523
actcacccac tcgccaccgc                                                   20


<210>  524
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  524
actcacccac tcgccaccgc                                                   20


<210>  525
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n is inosine

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  n is inosine

<400>  525
nctcncccac tcgccaccgc                                                   20


<210>  526
<211>  51
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  526

Gly Ala Gly Ala Gly Ala Gly Ala Gly Ala Gly Ala Gly Ala Gly Ala 
1               5                   10                  15      


Gly Ala Gly Ala Trp Ser Gly Arg Ala Arg Gly Arg Ala Arg Gly Gly 
            20                  25                  30          


Ala Ala Val Ala Val Pro Ala Pro Ala Ala Ala Glu Ala Gln Ala Val 
        35                  40                  45              


Ala Ser Gly 
    50      


<210>  527
<211>  52
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  527

Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
1               5                   10                  15      


Gly Pro Gly Arg Gly Arg Gly Gly Pro Gly Gly Gly Pro Gly Ala Gly 
            20                  25                  30          


Leu Arg Leu Arg Cys Leu Arg Pro Arg Arg Arg Arg Arg Arg Arg Trp 
        35                  40                  45              


Arg Val Gly Glu 
    50          


<210>  528
<211>  72
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  528

Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg Gly Arg 
1               5                   10                  15      


Gly Arg Gly Val Val Gly Ala Gly Pro Gly Ala Gly Pro Gly Arg Gly 
            20                  25                  30          


Cys Gly Cys Gly Ala Cys Ala Arg Gly Gly Gly Gly Ala Gly Gly Gly 
        35                  40                  45              


Glu Trp Val Ser Glu Glu Ala Ala Ser Trp Arg Val Ala Val Trp Gly 
    50                  55                  60                  


Ser Ala Ala Gly Lys Arg Arg Gly 
65                  70          


<210>  529
<211>  24
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  529

Pro Arg Pro Arg Pro Arg Pro Arg Pro Arg Pro Arg Pro Arg Pro Arg 
1               5                   10                  15      


Pro Arg Pro Leu Ala Arg Asp Ser 
            20                  


<210>  530
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  530

Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
1               5                   10                  15      


Gly Pro 
        


<210>  531
<211>  42
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  531

Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala 
1               5                   10                  15      


Pro Ala Pro Ser Ala Arg Leu Leu Ser Ser Arg Ala Cys Tyr Arg Leu 
            20                  25                  30          


Arg Leu Phe Pro Ser Leu Phe Ser Ser Gly 
        35                  40          


<210>  532
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  532
actcacccac tcgccaccgc                                                   20


<210>  533
<211>  6000
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 30 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 50 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 100 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 150 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 200 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 300 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 400 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 500 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 600 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 700 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 800 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 900 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 1000 times or more.

<400>  533
ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc       60

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3000

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3060

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     6000


<210>  534
<211>  3000
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 30 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 50 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 100 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 200 times or more. The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 300 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 400 times or more.  The 
       remaining "GGGGCC" may or may not be present.

<220>
<221>  misc_feature
<223>  In some embodiments, "GGGGCC" repeats 500 times or more.

<400>  534
ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc       60

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3000


<210>  535
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  535
ccttccctga aggttccucc                                                   20


<210>  536
<211>  19
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  536
agatgacgct tggtgtgtc                                                    19


<210>  537
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  537
taaacccaca cctgctcttg                                                   20


<210>  538
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  538
ctgctgcccg gttgcttctc ttt                                               23


<210>  539
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  539
ggtcagagaa atgagaggga aag                                               23


<210>  540
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  540
cgagtgggtg agtgagga                                                     18


<210>  541
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  541
aaatgcgtcg agctctgagg agag                                              24


<210>  542
<211>  6000
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  "GGGGCC" repeats at least 100 times and up to 1000 times.

<220>
<221>  misc_feature
<222>  (101)..(6000)
<223>  "GGGGCC" may or may not be present

<400>  542
ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc       60

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc      960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     1980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     2940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3000

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3060

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3120

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3180

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3240

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3300

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3360

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3420

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3480

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3540

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3600

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3660

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3720

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3780

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3840

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3900

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     3960

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4020

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4080

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4140

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4200

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4260

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4320

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4380

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4440

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4500

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4560

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4620

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4680

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4740

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4800

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4860

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4920

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     4980

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5040

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5100

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5160

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5220

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5280

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5340

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5400

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5460

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5520

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5580

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5640

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5700

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5760

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5820

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5880

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     5940

ggggccgggg ccggggccgg ggccggggcc ggggccgggg ccggggccgg ggccggggcc     6000


<210>  543
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  5AmMC12 on 5' end

<400>  543
tggcgagtgg                                                              10


<210>  544
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  3BioTEG on 3' end

<400>  544
gtgagtgagg                                                              10


<210>  545
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic


<220>
<221>  misc_feature
<223>  Cy3 marker on 5' end

<400>  545
ggccccggcc ccggcccc                                                     18


<210>  546
<211>  24
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  546
gguggcgagu gggugaguga ggag                                              24


<210>  547
<211>  12
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  547
auacuuaccu gg                                                           12


<210>  548
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  548
caaactttgc tttccctggt t                                                 21


<210>  549
<211>  20
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  549
tggcctgtat ccaacacttc                                                   20


<210>  550
<211>  27
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Synthetic

<400>  550
gcgtttgctc ttcttcuugc gttttuu                                           27


