                         SEQUENCE LISTING

<110>  Northwestern University
       Peter, Marcus  E.
       Murmann, Andrea E.
 
<120>  DUAL ACTIVITY SUPER TOXIC RNAi ACTIVE dsRNAs

<130>  5369-00602

<160>  27    

<170>  PatentIn version 3.5

<210>  1
<211>  19
<212>  RNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include a seed sequence that is 
       non-targeting in mammalian cells

<400>  1
ugguuuacau guuguguga                                                    19


<210>  2
<211>  19
<212>  RNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include a seed sequence that is 
       non-targeting in mammalian cells

<400>  2
ugguuuacau gucgacuaa                                                    19


<210>  3
<211>  19
<212>  RNA
<213>  Homo sapiens

<400>  3
gcccuucaau uacccauau                                                    19


<210>  4
<211>  19
<212>  RNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include seed sequence for human 
       CD95L exon 1

<400>  4
ugguuuacau gucccauaa                                                    19


<210>  5
<211>  19
<212>  RNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include a seed sequence that is 
       non-targeting in mammalian cells

<400>  5
ugguaaacua guugucuga                                                    19


<210>  6
<211>  19
<212>  RNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include seed sequence for human 
       CD95L exon 1

<400>  6
ugguaaacua gucccauaa                                                    19


<210>  7
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include CAG triplet repeat and 
       terminal dideoxynucleotide adenines

<400>  7
cagcagcagc agcagcagca a                                                 21


<210>  8
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include antisense sequence for siRNA
       containing CAG repeats and include dideoxynucleotide thymidines

<400>  8
gcugcugcug cugcugcugt t                                                 21


<210>  9
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  9
ctgctgctgc                                                              10


<210>  10
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  10
tctgagacca                                                              10


<210>  11
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  11
tgctgctgct                                                              10


<210>  12
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  12
gggggtgggg                                                              10


<210>  13
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  13
cctccctccc                                                              10


<210>  14
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  14
ccccgccccc                                                              10


<210>  15
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  15
ggccctggcc                                                              10


<210>  16
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  16
cactccccac                                                              10


<210>  17
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  17
ggcaggggtg                                                              10


<210>  18
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  18
gggggtgggg                                                              10


<210>  19
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  19
cctccctccc                                                              10


<210>  20
<211>  10
<212>  DNA
<213>  Homo sapien

<400>  20
ccccgccccc                                                              10


<210>  21
<211>  19
<212>  DNA
<213>  Homo sapien

<400>  21
gctgctgctg ctgctgctg                                                    19


<210>  22
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include CAG triplet repeat and 
       terminal dideoxynucleotide adenines

<400>  22
agcagcagca gcagcagcaa a                                                 21


<210>  23
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include antisense sequence for siRNA
       containing CAG repeats and include dideoxynucleotide thymidines

<400>  23
ugcugcugcu gcugcugcut t                                                 21


<210>  24
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include CAG triplet repeat and 
       terminal dideoxynucleotide adenines

<400>  24
gcagcagcag cagcagcaga a                                                 21


<210>  25
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial siRNA designed to include antisense sequence for siRNA
       containing CAG repeats and include dideoxynucleotide thymidines

<400>  25
cugcugcugc ugcugcugct t                                                 21


<210>  26
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial non-toxic scafflold sequence for guide strand of 
       artificial siRNA including dideoxynucleotide adenines


<220>
<221>  misc_feature
<222>  (2)..(7)
<223>  n is a, c, g, t or u

<400>  26
unnnnnnaca uguaaagcca a                                                 21


<210>  27
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Artificial non-toxic scafflold sequence for passenger strand of 
       artificial siRNA including dideoxynucleotide thymidines


<220>
<221>  misc_feature
<222>  (13)..(18)
<223>  n is a, c, g, t or u

<400>  27
cgguuuacau gunnnnnnat t                                                 21


