                         SEQUENCE LISTING

<110>  Mitotherapeutix LLC
       SHAO, Pengcheng  P
 
<120>  MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC 
       AGENTS

<130>  MIX-003WO(01)

<150>  US 62/821,628
<151>  2019-03-21

<150>  US 62/952,607
<151>  2019-12-23

<160>  4     

<170>  PatentIn version 3.5

<210>  1
<211>  21
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Oligonucleotide

<400>  1
aacucaauaa agugcuuuga a                                                 21


<210>  2
<211>  21
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(6)
<223>  Each residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (9)..(11)
<223>  Each residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (12)..(21)
<223>  Each residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (19)..(20)
<223>  Phosphorothioate linkage between residues 19 and 20

<220>
<221>  misc_feature
<222>  (20)..(21)
<223>  Phosphorothioate linkage between residues 20 and 21

<400>  2
aacucaauaa agugcuuuga a                                                 21


<210>  3
<211>  23
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Oligonucleotide

<400>  3
uucaaagcac uuuauugagu uuc                                               23


<210>  4
<211>  23
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Synthetic Oligonucleotide


<220>
<221>  misc_feature
<222>  (1)..(2)
<223>  Phosphorothioate linkage between residues 1 and 2

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  Residue has a 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (2)..(3)
<223>  Phosphorothioate linkage between residues 2 and 3

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  Residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (3)..(5)
<223>  Each residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (8)..(9)
<223>  Each residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (10)..(13)
<223>  Each residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  Residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  Residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (16)..(16)
<223>  Residue has 2-deoxy-2-fluoro (2'-F) ribo-sugar modification

<220>
<221>  misc_feature
<222>  (17)..(22)
<223>  Each residue has 2'-O-methyl (2'-OMe) ribo-sugar modification

<400>  4
uucaaagcac uuuauugagu uuc                                               23


