                         SEQUENCE LISTING

<110>  MCMASTER UNIVERSITY
 
<120>  DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE

<130>  16112-5 (156115) KAM

<140>  PCT/CA2020/050375
<141>  2020-03-20

<150>  US 62/821219
<151>  2019-03-20

<160>  6     

<170>  PatentIn version 3.5

<210>  1
<211>  81
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Biotinylated DNAzyme Reporter (BDR)


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n = methylene blue

<220>
<221>  misc_feature
<222>  (28)..(28)
<223>  n = riboA

<220>
<221>  misc_feature
<222>  (81)..(81)
<223>  n = biotin

<400>  1
nttttttgtg tgactcttcc tagctntggt tcgatcaaga gatgtgcgtc ttgatcgaga       60

cctgcgaccg tttttttttt n                                                 81


<210>  2
<211>  41
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Biotinylated DNAzyme Sequence


<220>
<221>  misc_feature
<222>  (41)..(41)
<223>  n = biotin

<400>  2
gatgtgcgtc ttgatcgaga cctgcgaccg tttttttttt n                           41


<210>  3
<211>  40
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Labeled DNA Reporter


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n = methylene blue

<220>
<221>  misc_feature
<222>  (26)..(26)
<223>  n = riboA

<400>  3
nttttttgtg tgactcttcc tagctntggt tcgatcaaga                             40


<210>  4
<211>  21
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Thiolated Probe


<220>
<221>  misc_feature
<222>  (21)..(21)
<223>  n = thiol

<400>  4
tagctaggaa gagtcacaca n                                                 21


<210>  5
<211>  26
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Ligation Template

<400>  5
caagacgcac atctcttgat cgaacc                                            26


<210>  6
<211>  100
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  DNAzyme


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  n = methylene blue

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  n = riboA

<220>
<221>  misc_feature
<222>  (100)..(100)
<223>  n = biotin

<400>  6
nactcttcct agctntggtt cgatcaagag atgtgcgttg tcgagacctg cgaccggaac       60

actacactgt gtggggatgg atttctttac agttgtgtgn                            100


