                               SEQUENCE LISTING

<110> REGENERON PHARMACEUTICALS, INC.
 
<120> ADENO-ASSOCIATED VIRUS VECTORS FOR THE DELIVERY OF THERAPEUTICS

<130> 67000-1023 WO

<140> PCT/US2020/020134
<141> 2020-02-27

<150> 62/878,865
<151> 2019-07-26

<150> 62/831,838
<151> 2019-04-10

<150> 62/812,017
<151> 2019-02-28

<160> 1278  

<170> PatentIn version 3.5

<210> 1
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 1
ttggcaagtg gacattttac tgg                                               23


<210> 2
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 2
tgtccacttg ccaaagaagt tgg                                               23


<210> 3
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 3
ggaccaactt ctttggcaag tgg                                               23


<210> 4
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 4
gaaaaatgga ccaacttctt tgg                                               23


<210> 5
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 5
ccatttttcc cactgctcac agg                                               23


<210> 6
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 6
cctgtgagca gtgggaaaaa tgg                                               23


<210> 7
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 7
tttttcccac tgctcacagg agg                                               23


<210> 8
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 8
tttcacctcc tgtgagcagt ggg                                               23


<210> 9
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 9
ttttcacctc ctgtgagcag tgg                                               23


<210> 10
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 10
agatctttga ggagctctga agg                                               23


<210> 11
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 11
aacagtatga aagatctttg agg                                               23


<210> 12
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 12
agcataaact ctaagctgtt tgg                                               23


<210> 13
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 13
acagcttaga gtttatgcta agg                                               23


<210> 14
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 14
cagcttagag tttatgctaa ggg                                               23


<210> 15
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 15
tcttttagtt ttaagttgga tgg                                               23


<210> 16
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 16
tttctctttt agttttaagt tgg                                               23


<210> 17
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 17
gtgataatgg gggctggggt ggg                                               23


<210> 18
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 18
agtgataatg ggggctgggg tgg                                               23


<210> 19
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 19
cagagtgata atgggggctg ggg                                               23


<210> 20
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 20
acagagtgat aatgggggct ggg                                               23


<210> 21
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 21
aacagagtga taatgggggc tgg                                               23


<210> 22
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 22
aaagaacaga gtgataatgg ggg                                               23


<210> 23
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 23
gaaagaacag agtgataatg ggg                                               23


<210> 24
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 24
agaaagaaca gagtgataat ggg                                               23


<210> 25
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 25
aagaaagaac agagtgataa tgg                                               23


<210> 26
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 26
tctgttcttt ctttttcctc agg                                               23


<210> 27
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 27
ttttcctcag gttcattaga tgg                                               23


<210> 28
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 28
ttggccatct aatgaacctg agg                                               23


<210> 29
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 29
aatgtagcag tagtactgct tgg                                               23


<210> 30
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 30
agcagtacta ctgctacatt tgg                                               23


<210> 31
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 31
tgaatcttga taacattatg ggg                                               23


<210> 32
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 32
ctgaatcttg ataacattat ggg                                               23


<210> 33
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 33
ccataatgtt atcaagattc agg                                               23


<210> 34
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 34
cctgaatctt gataacatta tgg                                               23


<210> 35
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 35
aatgttatca agattcaggt tgg                                               23


<210> 36
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 36
gttatcaaga ttcaggttgg agg                                               23


<210> 37
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 37
tgtttttcta gagaggctgc tgg                                               23


<210> 38
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 38
aaactagtgt ttttctagag agg                                               23


<210> 39
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 39
gaaaaacact agtttcacca agg                                               23


<210> 40
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 40
aacaactttt ttcttctcct tgg                                               23


<210> 41
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 41
ttgttttata ttgaaaacct tgg                                               23


<210> 42
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 42
gaaaaccttg gccataaacg tgg                                               23


<210> 43
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 43
cattgccacg tttatggcca agg                                               23


<210> 44
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 44
aatggacatt gccacgttta tgg                                               23


<210> 45
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 45
tgtccatttc catctcgtat agg                                               23


<210> 46
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 46
aatcctatac gagatggaaa tgg                                               23


<210> 47
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 47
caggcaaatc ctatacgaga tgg                                               23


<210> 48
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 48
tatttgggtt cacatatgac agg                                               23


<210> 49
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 49
tggcactttt atttttattt ggg                                               23


<210> 50
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 50
gtggcacttt tatttttatt tgg                                               23


<210> 51
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 51
aaatgagaat ttagtgcagg tgg                                               23


<210> 52
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 52
acgaaatgag aatttagtgc agg                                               23


<210> 53
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 53
attctcattt cgtctctaac agg                                               23


<210> 54
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 54
aaataaatgc tggagagaga ggg                                               23


<210> 55
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 55
gaaataaatg ctggagagag agg                                               23


<210> 56
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 56
attagggtcg aaataaatgc tgg                                               23


<210> 57
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 57
gcatttattt cgaccctaat tgg                                               23


<210> 58
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 58
aagaagaggg aaaccaatta ggg                                               23


<210> 59
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 59
gaagaagagg gaaaccaatt agg                                               23


<210> 60
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 60
actagatacg tcgaagaaga ggg                                               23


<210> 61
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 61
cactagatac gtcgaagaag agg                                               23


<210> 62
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 62
ctcttcttcg acgtatctag tgg                                               23


<210> 63
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 63
tgcaggctct gactcaggga agg                                               23


<210> 64
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 64
tttttgcagg ctctgactca ggg                                               23


<210> 65
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 65
ctttttgcag gctctgactc agg                                               23


<210> 66
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 66
tcagagcctg caaaaagcaa agg                                               23


<210> 67
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 67
ttcgttcctt tgctttttgc agg                                               23


<210> 68
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 68
gcaaaaagca aaggaacgaa tgg                                               23


<210> 69
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 69
agaaagtgca acaagcagaa agg                                               23


<210> 70
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 70
gaaagtgcaa caagcagaaa ggg                                               23


<210> 71
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 71
aaagtgcaac aagcagaaag ggg                                               23


<210> 72
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 72
aagtgcaaca agcagaaagg ggg                                               23


<210> 73
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 73
ggctgcaaag ctgcctgcct agg                                               23


<210> 74
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 74
gctgcaaagc tgcctgccta ggg                                               23


<210> 75
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 75
caggaaacgt agccctaggc agg                                               23


<210> 76
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 76
ctgcctaggg ctacgtttcc tgg                                               23


<210> 77
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 77
ttgccaggaa acgtagccct agg                                               23


<210> 78
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 78
tggctttcgg aagttttgcc agg                                               23


<210> 79
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 79
tcttttggag aaatggcttt cgg                                               23


<210> 80
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 80
aaagccattt ctccaaaaga agg                                               23


<210> 81
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 81
tagaccttct tttggagaaa tgg                                               23


<210> 82
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 82
tccaaaagaa ggtctagaag agg                                               23


<210> 83
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 83
tcctcttcta gaccttcttt tgg                                               23


<210> 84
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 84
aaaagaaggt ctagaagagg agg                                               23


<210> 85
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 85
agaaggtcta gaagaggagg agg                                               23


<210> 86
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 86
aggtctagaa gaggaggagg agg                                               23


<210> 87
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 87
tctagaagag gaggaggagg agg                                               23


<210> 88
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 88
agaggaggag gaggaggaga agg                                               23


<210> 89
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 89
ggaggaggag gaggagaagg agg                                               23


<210> 90
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 90
ggaggaggag gagaaggagg agg                                               23


<210> 91
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 91
ggaggaggag aaggaggagg agg                                               23


<210> 92
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 92
ggaggagaag gaggaggagg agg                                               23


<210> 93
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 93
ggagaaggag gaggaggagg agg                                               23


<210> 94
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 94
cagcatgaaa gagccccact tgg                                               23


<210> 95
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 95
atgaaagagc cccacttgga agg                                               23


<210> 96
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 96
aaagagcccc acttggaagg cgg                                               23


<210> 97
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 97
gccccacttg gaaggcggtt tgg                                               23


<210> 98
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 98
tccaaaccgc cttccaagtg ggg                                               23


<210> 99
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 99
atccaaaccg ccttccaagt ggg                                               23


<210> 100
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 100
aatccaaacc gccttccaag tgg                                               23


<210> 101
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 101
gattttattt gtgtgttttg tgg                                               23


<210> 102
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 102
catcttacac caaactcatc tgg                                               23


<210> 103
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 103
tttttaatgc cagatgagtt tgg                                               23


<210> 104
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 104
attcattctc ctgacatgtc tgg                                               23


<210> 105
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 105
ttcattctcc tgacatgtct ggg                                               23


<210> 106
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 106
ctcctgacat gtctgggact tgg                                               23


<210> 107
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 107
aaccaagtcc cagacatgtc agg                                               23


<210> 108
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 108
acatgtctgg gacttggttt agg                                               23


<210> 109
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 109
ctgggacttg gtttaggaaa agg                                               23


<210> 110
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 110
ggtttaggaa aaggaagcaa agg                                               23


<210> 111
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 111
gtttaggaaa aggaagcaaa ggg                                               23


<210> 112
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 112
aggaaaagga agcaaaggga tgg                                               23


<210> 113
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 113
aggaagcaaa gggatggaga agg                                               23


<210> 114
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 114
tggagtttta cggctgtact tgg                                               23


<210> 115
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 115
gacacacttg tggagtttta cgg                                               23


<210> 116
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 116
agcggaactt gacacacttg tgg                                               23


<210> 117
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 117
gtcgtaggat cagcacaaag cgg                                               23


<210> 118
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 118
ttggtaaatt tcgtagtcgt agg                                               23


<210> 119
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 119
atttaccaaa acagtccaaa agg                                               23


<210> 120
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 120
tagaaccttt tggactgttt tgg                                               23


<210> 121
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 121
atacattctt tagaaccttt tgg                                               23


<210> 122
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 122
taggattctt aaaactagta tgg                                               23


<210> 123
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 123
atactagttt taagaatcct agg                                               23


<210> 124
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 124
tcctaggaaa agatgtaact agg                                               23


<210> 125
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 125
tcctagttac atcttttcct agg                                               23


<210> 126
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 126
taggaaaaga tgtaactagg agg                                               23


<210> 127
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 127
taactaggag gtaagatgta agg                                               23


<210> 128
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 128
ggaggtaaga tgtaaggaac agg                                               23


<210> 129
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 129
taatgatgct ttggattggt agg                                               23


<210> 130
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 130
aagctaatga tgctttggat tgg                                               23


<210> 131
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 131
gttttaagct aatgatgctt tgg                                               23


<210> 132
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 132
taaaacttta aagagacaac tgg                                               23


<210> 133
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 133
aaaactttaa agagacaact ggg                                               23


<210> 134
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 134
ggaaatggaa aatagaaaat agg                                               23


<210> 135
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 135
ttatttattg tttttggaaa tgg                                               23


<210> 136
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 136
ttcgttttat ttattgtttt tgg                                               23


<210> 137
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 137
gtagtctcag tgttcagaca tgg                                               23


<210> 138
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 138
ttcagacatg gccaagtttt agg                                               23


<210> 139
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 139
tcagacatgg ccaagtttta ggg                                               23


<210> 140
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 140
cagacatggc caagttttag ggg                                               23


<210> 141
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 141
acatggccaa gttttagggg tgg                                               23


<210> 142
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 142
actaaaccac ccctaaaact tgg                                               23


<210> 143
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 143
tttaggggtg gtttagtttt agg                                               23


<210> 144
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 144
ttaggggtgg tttagtttta ggg                                               23


<210> 145
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 145
taggggtggt ttagttttag ggg                                               23


<210> 146
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 146
tgtctatttt tgctttccac tgg                                               23


<210> 147
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 147
gtctattttt gctttccact ggg                                               23


<210> 148
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 148
tctatttttg ctttccactg ggg                                               23


<210> 149
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 149
ataatggaat ctcaccccag tgg                                               23


<210> 150
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 150
tggggtgaga ttccattatt tgg                                               23


<210> 151
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 151
ggggtgagat tccattattt ggg                                               23


<210> 152
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 152
gggtgagatt ccattatttg ggg                                               23


<210> 153
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 153
ccattatttg gggtaatcag tgg                                               23


<210> 154
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 154
ccactgatta ccccaaataa tgg                                               23


<210> 155
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 155
cattatttgg ggtaatcagt ggg                                               23


<210> 156
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 156
atttggggta atcagtgggt agg                                               23


<210> 157
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 157
tttggggtaa tcagtgggta ggg                                               23


<210> 158
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 158
atcagtgggt agggaattga agg                                               23


<210> 159
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 159
ttttttttga gttttattac tgg                                               23


<210> 160
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 160
tgtggtgtga tggaagattc agg                                               23


<210> 161
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 161
actataattt tgtggtgtga tgg                                               23


<210> 162
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 162
agtttttaac tataattttg tgg                                               23


<210> 163
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 163
aaagaccttc atatttacca agg                                               23


<210> 164
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 164
tgaatccttg gtaaatatga agg                                               23


<210> 165
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 165
tttttaattg gctgaatcct tgg                                               23


<210> 166
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 166
ggacagtaat aatttttaat tgg                                               23


<210> 167
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 167
actgtccttt agattcctac tgg                                               23


<210> 168
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 168
agaaaccagt aggaatctaa agg                                               23


<210> 169
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 169
cacttcagct agaaaccagt agg                                               23


<210> 170
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 170
tggtttctag ctgaagtgtt tgg                                               23


<210> 171
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 171
ggtttctagc tgaagtgttt ggg                                               23


<210> 172
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 172
agtgcggtaa gaaagaacgg tgg                                               23


<210> 173
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 173
ttcagtgcgg taagaaagaa cgg                                               23


<210> 174
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 174
tgatttactg gatttcagtg cgg                                               23


<210> 175
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 175
caaagagctg agtgatttac tgg                                               23


<210> 176
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 176
cagctctttg tccgtcccta agg                                               23


<210> 177
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 177
gcgaatggct gccttaggga cgg                                               23


<210> 178
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 178
aacagcgaat ggctgcctta ggg                                               23


<210> 179
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 179
caacagcgaa tggctgcctt agg                                               23


<210> 180
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 180
ctaaggcagc cattcgctgt tgg                                               23


<210> 181
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 181
aatgcatcac caacagcgaa tgg                                               23


<210> 182
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 182
atcacacaaa cctagaaaca tgg                                               23


<210> 183
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 183
gcggttattt ccatgtttct agg                                               23


<210> 184
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 184
gggactggat tttctgattg cgg                                               23


<210> 185
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 185
gaaaatccag tcccaatcct tgg                                               23


<210> 186
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 186
ttttctccaa ggattgggac tgg                                               23


<210> 187
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 187
ttgtgttttc tccaaggatt ggg                                               23


<210> 188
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 188
attgtgtttt ctccaaggat tgg                                               23


<210> 189
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 189
atccttggag aaaacacaat cgg                                               23


<210> 190
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence (including PAM)"

<400> 190
atccgattgt gttttctcca agg                                               23


<210> 191
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 191
ggggaggagg ccagggcagc agg                                               23


<210> 192
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 192
gggcagcagg accccccccg cgg                                               23


<210> 193
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 193
ggcagcagga ccccccccgc ggg                                               23


<210> 194
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 194
gacccccccc gcgggttatg tgg                                               23


<210> 195
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 195
accccccccg cgggttatgt ggg                                               23


<210> 196
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 196
ccccccccgc gggttatgtg ggg                                               23


<210> 197
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 197
ccccacataa cccgcggggg ggg                                               23


<210> 198
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 198
gccccacata acccgcgggg ggg                                               23


<210> 199
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 199
tgccccacat aacccgcggg ggg                                               23


<210> 200
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 200
ctgccccaca taacccgcgg ggg                                               23


<210> 201
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 201
tctgccccac ataacccgcg ggg                                               23


<210> 202
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 202
ctctgcccca cataacccgc ggg                                               23


<210> 203
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 203
gctctgcccc acataacccg cgg                                               23


<210> 204
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 204
gcagagcaag aatcctgaaa agg                                               23


<210> 205
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 205
gagcaagaat cctgaaaagg agg                                               23


<210> 206
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 206
agaatcctga aaaggaggag tgg                                               23


<210> 207
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 207
tacatccact cctccttttc agg                                               23


<210> 208
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 208
ggaggagtgg atgtactccg tgg                                               23


<210> 209
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 209
ggatgtactc cgtggagtag agg                                               23


<210> 210
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 210
ctccgtggag tagaggccgt tgg                                               23


<210> 211
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 211
ggccaacggc ctctactcca cgg                                               23


<210> 212
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 212
tggagtagag gccgttggcc tgg                                               23


<210> 213
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 213
aggccgttgg cctggtccga cgg                                               23


<210> 214
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 214
atgccgtcgg accaggccaa cgg                                               23


<210> 215
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 215
ggtgcagatg ccgtcggacc agg                                               23


<210> 216
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 216
ggtctgggtg cagatgccgt cgg                                               23


<210> 217
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 217
acggcatctg cacccagacc tgg                                               23


<210> 218
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 218
ctgcacccag acctggtcgt tgg                                               23


<210> 219
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 219
tgcacccaga cctggtcgtt ggg                                               23


<210> 220
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 220
gcggcccaac gaccaggtct ggg                                               23


<210> 221
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 221
tgcggcccaa cgaccaggtc tgg                                               23


<210> 222
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 222
cctggtcgtt gggccgcagc tgg                                               23


<210> 223
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 223
ccagctgcgg cccaacgacc agg                                               23


<210> 224
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 224
gttgggccgc agctggagca cgg                                               23


<210> 225
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 225
gtggggccgt gctccagctg cgg                                               23


<210> 226
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 226
gcacggcccc accagatgcc tgg                                               23


<210> 227
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 227
ccccaccaga tgcctggtcc agg                                               23


<210> 228
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 228
cctggaccag gcatctggtg ggg                                               23


<210> 229
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 229
acctggacca ggcatctggt ggg                                               23


<210> 230
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 230
tacctggacc aggcatctgg tgg                                               23


<210> 231
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 231
ggctacctgg accaggcatc tgg                                               23


<210> 232
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 232
caagaagggc tacctggacc agg                                               23


<210> 233
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 233
tgagtacaag aagggctacc tgg                                               23


<210> 234
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 234
gcccttcttg tactcatcgt agg                                               23


<210> 235
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 235
acctacgatg agtacaagaa ggg                                               23


<210> 236
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 236
tacctacgat gagtacaaga agg                                               23


<210> 237
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 237
cttgtactca tcgtaggtat agg                                               23


<210> 238
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 238
gtactcatcg taggtatagg tgg                                               23


<210> 239
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 239
tcatcgtagg tataggtggc cgg                                               23


<210> 240
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 240
ccggcacgtt gttcttgtac agg                                               23


<210> 241
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 241
cctgtacaag aacaacgtgc cgg                                               23


<210> 242
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 242
cggcacgttg ttcttgtaca ggg                                               23


<210> 243
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 243
gtacagggcc acccacacgt tgg                                               23


<210> 244
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 244
caagggcacc aacgtgtggg tgg                                               23


<210> 245
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 245
cgtcaagggc accaacgtgt ggg                                               23


<210> 246
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 246
acgtcaaggg caccaacgtg tgg                                               23


<210> 247
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 247
tggtgccctt gacgtgcaca tgg                                               23


<210> 248
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 248
gcttaccatg tgcacgtcaa ggg                                               23


<210> 249
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 249
tgcttaccat gtgcacgtca agg                                               23


<210> 250
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 250
aagtagtaga cgccgcccac agg                                               23


<210> 251
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 251
agtagtagac gccgcccaca ggg                                               23


<210> 252
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 252
gtagacgccg cccacagggc agg                                               23


<210> 253
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 253
atcttcacct gccctgtggg cgg                                               23


<210> 254
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 254
ggcatcttca cctgccctgt ggg                                               23


<210> 255
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 255
tggcatcttc acctgccctg tgg                                               23


<210> 256
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 256
agggcaggtg aagatgccag tgg                                               23


<210> 257
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 257
caggtgaaga tgccagtggc tgg                                               23


<210> 258
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 258
aggtgaagat gccagtggct ggg                                               23


<210> 259
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 259
agcggctaca acccagccac tgg                                               23


<210> 260
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 260
tggctgggtt gtagccgctg tgg                                               23


<210> 261
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 261
actctctaca atggccacag cgg                                               23


<210> 262
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 262
tgtggccatt gtagagagtc cgg                                               23


<210> 263
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 263
tttgaccgga ctctctacaa tgg                                               23


<210> 264
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 264
gagagtccgg tcaaatttca cgg                                               23


<210> 265
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 265
agagtccggt caaatttcac ggg                                               23


<210> 266
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 266
gcatgcccgt gaaatttgac cgg                                               23


<210> 267
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 267
aaatttcacg ggcatgcccg agg                                               23


<210> 268
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 268
tttcacgggc atgcccgagg cgg                                               23


<210> 269
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 269
ttcacgggca tgcccgaggc ggg                                               23


<210> 270
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 270
tcacgggcat gcccgaggcg ggg                                               23


<210> 271
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 271
gggcatgccc gaggcgggga agg                                               23


<210> 272
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 272
ggcatgcccg aggcggggaa ggg                                               23


<210> 273
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 273
gcccgaggcg gggaagggcg agg                                               23


<210> 274
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 274
acctcgccct tccccgcctc ggg                                               23


<210> 275
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 275
cacctcgccc ttccccgcct cgg                                               23


<210> 276
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 276
cgaggtgagc accgcagtga agg                                               23


<210> 277
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 277
gtgagcaccg cagtgaaggc cgg                                               23


<210> 278
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 278
caccgcagtg aaggccggtg tgg                                               23


<210> 279
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 279
tgccacaccg gccttcactg cgg                                               23


<210> 280
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 280
cagtgaaggc cggtgtggca tgg                                               23


<210> 281
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 281
agtgaaggcc ggtgtggcat ggg                                               23


<210> 282
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 282
gctgtctgcc catgccacac cgg                                               23


<210> 283
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 283
agctcgccca gcccaaactg tgg                                               23


<210> 284
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 284
ggcaagccac agtttgggct ggg                                               23


<210> 285
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 285
gggcaagcca cagtttgggc tgg                                               23


<210> 286
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 286
aggggggcaa gccacagttt ggg                                               23


<210> 287
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 287
aaggggggca agccacagtt tgg                                               23


<210> 288
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 288
cttgcccccc ttgcccagca cgg                                               23


<210> 289
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 289
ggtgccgtgc tgggcaaggg ggg                                               23


<210> 290
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 290
gggtgccgtg ctgggcaagg ggg                                               23


<210> 291
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 291
agggtgccgt gctgggcaag ggg                                               23


<210> 292
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 292
gagggtgccg tgctgggcaa ggg                                               23


<210> 293
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 293
ggagggtgcc gtgctgggca agg                                               23


<210> 294
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 294
ggtgtggagg gtgccgtgct ggg                                               23


<210> 295
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 295
cggtgtggag ggtgccgtgc tgg                                               23


<210> 296
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 296
ggcaccctcc acaccgccgt tgg                                               23


<210> 297
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 297
gcaccctcca caccgccgtt ggg                                               23


<210> 298
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 298
ctgcccaacg gcggtgtgga ggg                                               23


<210> 299
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 299
cctccacacc gccgttgggc agg                                               23


<210> 300
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 300
cctgcccaac ggcggtgtgg agg                                               23


<210> 301
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 301
gcacctgccc aacggcggtg tgg                                               23


<210> 302
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 302
ggcttgcacc tgcccaacgg cgg                                               23


<210> 303
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 303
gcaggcttgc acctgcccaa cgg                                               23


<210> 304
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 304
ttcgatgaga ctggcatcgc agg                                               23


<210> 305
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 305
tgcgatgcca gtctcatcga agg                                               23


<210> 306
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 306
ccagtctcat cgaaggcccc agg                                               23


<210> 307
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 307
cctggggcct tcgatgagac tgg                                               23


<210> 308
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 308
cagtctcatc gaaggcccca ggg                                               23


<210> 309
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 309
agtctcatcg aaggccccag ggg                                               23


<210> 310
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 310
tcgaaggccc caggggcacc agg                                               23


<210> 311
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 311
cgaaggcccc aggggcacca ggg                                               23


<210> 312
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 312
gaaggcccca ggggcaccag ggg                                               23


<210> 313
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 313
aaggccccag gggcaccagg ggg                                               23


<210> 314
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 314
gggaccccct ggtgcccctg ggg                                               23


<210> 315
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 315
cgggaccccc tggtgcccct ggg                                               23


<210> 316
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 316
ccaggggcac cagggggtcc cgg                                               23


<210> 317
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 317
ccgggacccc ctggtgcccc tgg                                               23


<210> 318
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 318
caggggcacc agggggtccc ggg                                               23


<210> 319
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 319
aggggcacca gggggtcccg ggg                                               23


<210> 320
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 320
ggggcaccag ggggtcccgg ggg                                               23


<210> 321
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 321
accagggggt cccgggggcc cgg                                               23


<210> 322
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 322
ccagggggtc ccgggggccc ggg                                               23


<210> 323
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 323
cccgggcccc cgggaccccc tgg                                               23


<210> 324
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 324
gggggtcccg ggggcccggg agg                                               23


<210> 325
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 325
cccgggggcc cgggaggccc cgg                                               23


<210> 326
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 326
ccggggcctc ccgggccccc ggg                                               23


<210> 327
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 327
tccggggcct cccgggcccc cgg                                               23


<210> 328
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 328
gggggcccgg gaggccccgg agg                                               23


<210> 329
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 329
ggggcccggg aggccccgga ggg                                               23


<210> 330
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 330
cgggccctcc ggggcctccc ggg                                               23


<210> 331
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 331
acgggccctc cggggcctcc cgg                                               23


<210> 332
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 332
ctggaatcac gggccctccg ggg                                               23


<210> 333
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 333
cccggagggc ccgtgattcc agg                                               23


<210> 334
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 334
cctggaatca cgggccctcc ggg                                               23


<210> 335
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 335
ccggagggcc cgtgattcca ggg                                               23


<210> 336
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 336
ccctggaatc acgggccctc cgg                                               23


<210> 337
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 337
cggagggccc gtgattccag ggg                                               23


<210> 338
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 338
cccgtgattc caggggagcc agg                                               23


<210> 339
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 339
cctggctccc ctggaatcac ggg                                               23


<210> 340
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 340
ccgtgattcc aggggagcca ggg                                               23


<210> 341
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 341
ccctggctcc cctggaatca cgg                                               23


<210> 342
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 342
ccaggggagc cagggacccc tgg                                               23


<210> 343
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 343
ccaggggtcc ctggctcccc tgg                                               23


<210> 344
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 344
caggggagcc agggacccct ggg                                               23


<210> 345
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 345
aggggagcca gggacccctg ggg                                               23


<210> 346
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 346
ggggagccag ggacccctgg ggg                                               23


<210> 347
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 347
acggggcccc caggggtccc tgg                                               23


<210> 348
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 348
agggacccct gggggccccg tgg                                               23


<210> 349
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 349
gggacccctg ggggccccgt ggg                                               23


<210> 350
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 350
tgggcccacg gggcccccag ggg                                               23


<210> 351
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 351
ctgggcccac ggggccccca ggg                                               23


<210> 352
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 352
gctgggccca cggggccccc agg                                               23


<210> 353
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 353
ctggcacggc tgggcccacg ggg                                               23


<210> 354
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 354
cccgtgggcc cagccgtgcc agg                                               23


<210> 355
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 355
cctggcacgg ctgggcccac ggg                                               23


<210> 356
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 356
acctggcacg gctgggccca cgg                                               23


<210> 357
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 357
caggggaacc tggcacggct ggg                                               23


<210> 358
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 358
gcaggggaac ctggcacggc tgg                                               23


<210> 359
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 359
gagagcaggg gaacctggca cgg                                               23


<210> 360
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 360
gaggggagag caggggaacc tgg                                               23


<210> 361
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 361
tcccctgctc tcccctctcc agg                                               23


<210> 362
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 362
cccctgctct cccctctcca ggg                                               23


<210> 363
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 363
ccctggagag gggagagcag ggg                                               23


<210> 364
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 364
ccctgctctc ccctctccag ggg                                               23


<210> 365
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 365
cccctggaga ggggagagca ggg                                               23


<210> 366
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 366
cctgctctcc cctctccagg ggg                                               23


<210> 367
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 367
ccccctggag aggggagagc agg                                               23


<210> 368
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 368
ctcccctctc cagggggccc tgg                                               23


<210> 369
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 369
tgccagggcc ccctggagag ggg                                               23


<210> 370
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 370
ctgccagggc cccctggaga ggg                                               23


<210> 371
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 371
cctctccagg gggccctggc agg                                               23


<210> 372
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 372
cctgccaggg ccccctggag agg                                               23


<210> 373
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 373
ccagggggcc ctggcaggcc tgg                                               23


<210> 374
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 374
ccaggcctgc cagggccccc tgg                                               23


<210> 375
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 375
agggggaacc aggcctgcca ggg                                               23


<210> 376
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 376
aagggggaac caggcctgcc agg                                               23


<210> 377
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 377
gcaggcctgg ttcccccttc agg                                               23


<210> 378
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 378
cctggttccc ccttcaggcc cgg                                               23


<210> 379
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 379
ccgggcctga agggggaacc agg                                               23


<210> 380
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 380
gttccccctt caggcccggc agg                                               23


<210> 381
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 381
aggcctgccg ggcctgaagg ggg                                               23


<210> 382
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 382
aaggcctgcc gggcctgaag ggg                                               23


<210> 383
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 383
caaggcctgc cgggcctgaa ggg                                               23


<210> 384
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 384
ccttcaggcc cggcaggcct tgg                                               23


<210> 385
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 385
ccaaggcctg ccgggcctga agg                                               23


<210> 386
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 386
cttcaggccc ggcaggcctt ggg                                               23


<210> 387
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 387
ttcaggcccg gcaggccttg ggg                                               23


<210> 388
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 388
attgggcccc aaggcctgcc ggg                                               23


<210> 389
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 389
tattgggccc caaggcctgc cgg                                               23


<210> 390
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 390
ggcaggcctt ggggcccaat agg                                               23


<210> 391
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 391
gcaggccttg gggcccaata ggg                                               23


<210> 392
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 392
gctggcccta ttgggcccca agg                                               23


<210> 393
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 393
tggggcccaa tagggccagc tgg                                               23


<210> 394
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 394
agggtccagc tggccctatt ggg                                               23


<210> 395
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 395
cagggtccag ctggccctat tgg                                               23


<210> 396
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 396
caatagggcc agctggaccc tgg                                               23


<210> 397
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 397
ccagctggac cctggagtcc tgg                                               23


<210> 398
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 398
ccaggactcc agggtccagc tgg                                               23


<210> 399
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 399
cagctggacc ctggagtcct ggg                                               23


<210> 400
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 400
tcaggaatcc caggactcca ggg                                               23


<210> 401
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 401
ctcaggaatc ccaggactcc agg                                               23


<210> 402
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 402
ctggagtcct gggattcctg agg                                               23


<210> 403
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 403
tggagtcctg ggattcctga ggg                                               23


<210> 404
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 404
aggggtccct caggaatccc agg                                               23


<210> 405
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 405
ggattcctga gggacccctc agg                                               23


<210> 406
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 406
cctgagggac ccctcaggcc agg                                               23


<210> 407
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 407
cctggcctga ggggtccctc agg                                               23


<210> 408
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 408
cccctcaggc caggctgccc agg                                               23


<210> 409
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 409
cctgggcagc ctggcctgag ggg                                               23


<210> 410
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 410
ccctcaggcc aggctgccca ggg                                               23


<210> 411
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 411
ccctgggcag cctggcctga ggg                                               23


<210> 412
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 412
tccctgggca gcctggcctg agg                                               23


<210> 413
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 413
ttggggctcc ctgggcagcc tgg                                               23


<210> 414
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 414
aaggtgactt ggggctccct ggg                                               23


<210> 415
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 415
aaaggtgact tggggctccc tgg                                               23


<210> 416
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 416
tggggcagaa aggtgacttg ggg                                               23


<210> 417
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 417
ctggggcaga aaggtgactt ggg                                               23


<210> 418
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 418
ccaagtcacc tttctgcccc agg                                               23


<210> 419
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 419
cctggggcag aaaggtgact tgg                                               23


<210> 420
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 420
caagtcacct ttctgcccca ggg                                               23


<210> 421
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 421
gcaggagccc tggggcagaa agg                                               23


<210> 422
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 422
caggggtggc aggagccctg ggg                                               23


<210> 423
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 423
cccagggctc ctgccacccc tgg                                               23


<210> 424
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 424
ccaggggtgg caggagccct ggg                                               23


<210> 425
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 425
accaggggtg gcaggagccc tgg                                               23


<210> 426
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 426
cctgccaccc ctggtcctcc agg                                               23


<210> 427
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 427
cctggaggac caggggtggc agg                                               23


<210> 428
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 428
ctgccacccc tggtcctcca ggg                                               23


<210> 429
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 429
tcgccctgga ggaccagggg tgg                                               23


<210> 430
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 430
gggtcgccct ggaggaccag ggg                                               23


<210> 431
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 431
cgggtcgccc tggaggacca ggg                                               23


<210> 432
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 432
acgggtcgcc ctggaggacc agg                                               23


<210> 433
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 433
ggtttcacgg gtcgccctgg agg                                               23


<210> 434
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 434
ccagggcgac ccgtgaaacc cgg                                               23


<210> 435
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 435
ccgggtttca cgggtcgccc tgg                                               23


<210> 436
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 436
aagggtgagc cgggtttcac ggg                                               23


<210> 437
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 437
caagggtgag ccgggtttca cgg                                               23


<210> 438
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 438
cgtgaaaccc ggctcaccct tgg                                               23


<210> 439
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 439
gtgaaacccg gctcaccctt ggg                                               23


<210> 440
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 440
actgggccca agggtgagcc ggg                                               23


<210> 441
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 441
aactgggccc aagggtgagc cgg                                               23


<210> 442
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 442
ggctcaccct tgggcccagt tgg                                               23


<210> 443
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 443
cccttgggcc cagttggtcc agg                                               23


<210> 444
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 444
cctggaccaa ctgggcccaa ggg                                               23


<210> 445
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 445
ccttgggccc agttggtcca ggg                                               23


<210> 446
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 446
ccctggacca actgggccca agg                                               23


<210> 447
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 447
cttgggccca gttggtccag ggg                                               23


<210> 448
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 448
ttgggcccag ttggtccagg ggg                                               23


<210> 449
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 449
atggaccccc tggaccaact ggg                                               23


<210> 450
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 450
catggacccc ctggaccaac tgg                                               23


<210> 451
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 451
cagttggtcc agggggtcca tgg                                               23


<210> 452
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 452
agttggtcca gggggtccat ggg                                               23


<210> 453
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 453
ccagggggtc catgggcccc agg                                               23


<210> 454
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 454
cctggggccc atggaccccc tgg                                               23


<210> 455
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 455
aggggacttc ctggggccca tgg                                               23


<210> 456
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 456
aggtgagagg ggacttcctg ggg                                               23


<210> 457
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 457
caggtgagag gggacttcct ggg                                               23


<210> 458
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 458
ccaggaagtc ccctctcacc tgg                                               23


<210> 459
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 459
ccaggtgaga ggggacttcc tgg                                               23


<210> 460
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 460
caggaagtcc cctctcacct ggg                                               23


<210> 461
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 461
cccctctcac ctgggacccc tgg                                               23


<210> 462
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 462
ccaggggtcc caggtgagag ggg                                               23


<210> 463
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 463
accaggggtc ccaggtgaga ggg                                               23


<210> 464
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 464
aaccaggggt cccaggtgag agg                                               23


<210> 465
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 465
gctgggaaac caggggtccc agg                                               23


<210> 466
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 466
ggacccctgg tttcccagcc agg                                               23


<210> 467
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 467
tggcctggct gggaaaccag ggg                                               23


<210> 468
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 468
gtggcctggc tgggaaacca ggg                                               23


<210> 469
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 469
agtggcctgg ctgggaaacc agg                                               23


<210> 470
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 470
ggtttcccag ccaggccact agg                                               23


<210> 471
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 471
aggggcctag tggcctggct ggg                                               23


<210> 472
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 472
caggggccta gtggcctggc tgg                                               23


<210> 473
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 473
cagccaggcc actaggcccc tgg                                               23


<210> 474
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 474
tgaccagggg cctagtggcc tgg                                               23


<210> 475
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 475
cgaggtgacc aggggcctag tgg                                               23


<210> 476
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 476
ctggcattcg aggtgaccag ggg                                               23


<210> 477
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 477
ccctggtcac ctcgaatgcc agg                                               23


<210> 478
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 478
cctggcattc gaggtgacca ggg                                               23


<210> 479
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 479
gcctggcatt cgaggtgacc agg                                               23


<210> 480
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 480
cctcgaatgc caggcactcc tgg                                               23


<210> 481
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 481
ccaggagtgc ctggcattcg agg                                               23


<210> 482
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 482
ctcgaatgcc aggcactcct ggg                                               23


<210> 483
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 483
tcgaatgcca ggcactcctg ggg                                               23


<210> 484
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 484
cgaatgccag gcactcctgg ggg                                               23


<210> 485
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 485
ggaggacccc caggagtgcc tgg                                               23


<210> 486
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 486
ggcactcctg ggggtcctcc agg                                               23


<210> 487
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 487
gcagggcctg gaggaccccc agg                                               23


<210> 488
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 488
aagggtgagg cagggcctgg agg                                               23


<210> 489
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 489
ccaggccctg cctcaccctt agg                                               23


<210> 490
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 490
cctaagggtg aggcagggcc tgg                                               23


<210> 491
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 491
ctgggcctaa gggtgaggca ggg                                               23


<210> 492
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 492
cctgcctcac ccttaggccc agg                                               23


<210> 493
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 493
cctgggccta agggtgaggc agg                                               23


<210> 494
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 494
ctgcctcacc cttaggccca ggg                                               23


<210> 495
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 495
tgcctcaccc ttaggcccag ggg                                               23


<210> 496
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 496
gcctcaccct taggcccagg ggg                                               23


<210> 497
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 497
gccccctggg cctaagggtg agg                                               23


<210> 498
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 498
cgtgggcccc ctgggcctaa ggg                                               23


<210> 499
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 499
acgtgggccc cctgggccta agg                                               23


<210> 500
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 500
ctggcagacg tgggccccct ggg                                               23


<210> 501
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 501
ccagggggcc cacgtctgcc agg                                               23


<210> 502
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 502
cctggcagac gtgggccccc tgg                                               23


<210> 503
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 503
cagggcttcc tggcagacgt ggg                                               23


<210> 504
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 504
gcagggcttc ctggcagacg tgg                                               23


<210> 505
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 505
ccaggaagcc ctgcagaccc agg                                               23


<210> 506
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 506
cctgggtctg cagggcttcc tgg                                               23


<210> 507
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 507
ctggacttcc tgggtctgca ggg                                               23


<210> 508
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 508
cctgcagacc caggaagtcc agg                                               23


<210> 509
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 509
cctggacttc ctgggtctgc agg                                               23


<210> 510
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 510
ctgcagaccc aggaagtcca ggg                                               23


<210> 511
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 511
tgcagaccca ggaagtccag ggg                                               23


<210> 512
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 512
gcagacccag gaagtccagg ggg                                               23


<210> 513
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 513
ggggtccccc tggacttcct ggg                                               23


<210> 514
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 514
gggggtcccc ctggacttcc tgg                                               23


<210> 515
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 515
cagggtcttg ggggtccccc tgg                                               23


<210> 516
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 516
gggggacccc caagaccctg tgg                                               23


<210> 517
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 517
ggggaccccc aagaccctgt ggg                                               23


<210> 518
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 518
cagggcccac agggtcttgg ggg                                               23


<210> 519
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 519
gcagggccca cagggtcttg ggg                                               23


<210> 520
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 520
agcagggccc acagggtctt ggg                                               23


<210> 521
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 521
gagcagggcc cacagggtct tgg                                               23


<210> 522
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 522
ccctgtgggc cctgctcccc tgg                                               23


<210> 523
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 523
ccaggggagc agggcccaca ggg                                               23


<210> 524
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 524
gccaggggag cagggcccac agg                                               23


<210> 525
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 525
gatggggagc caggggagca ggg                                               23


<210> 526
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 526
ggatggggag ccaggggagc agg                                               23


<210> 527
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 527
aggggaggat ggggagccag ggg                                               23


<210> 528
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 528
caggggagga tggggagcca ggg                                               23


<210> 529
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 529
cctggctccc catcctcccc tgg                                               23


<210> 530
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 530
ccaggggagg atggggagcc agg                                               23


<210> 531
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 531
gggtgagcca ggggaggatg ggg                                               23


<210> 532
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 532
ggggtgagcc aggggaggat ggg                                               23


<210> 533
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 533
aggggtgagc caggggagga tgg                                               23


<210> 534
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 534
ggacaggggt gagccagggg agg                                               23


<210> 535
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 535
gggggacagg ggtgagccag ggg                                               23


<210> 536
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 536
tgggggacag gggtgagcca ggg                                               23


<210> 537
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 537
ttgggggaca ggggtgagcc agg                                               23


<210> 538
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 538
cccctgtccc ccaagagtcc tgg                                               23


<210> 539
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 539
ccaggactct tgggggacag ggg                                               23


<210> 540
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 540
ccctgtcccc caagagtcct ggg                                               23


<210> 541
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 541
cccaggactc ttgggggaca ggg                                               23


<210> 542
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 542
tcccaggact cttgggggac agg                                               23


<210> 543
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 543
tggggtccca ggactcttgg ggg                                               23


<210> 544
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 544
ctggggtccc aggactcttg ggg                                               23


<210> 545
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 545
gctggggtcc caggactctt ggg                                               23


<210> 546
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 546
agctggggtc ccaggactct tgg                                               23


<210> 547
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 547
aagagtcctg ggaccccagc tgg                                               23


<210> 548
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 548
agagtcctgg gaccccagct ggg                                               23


<210> 549
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 549
aggggcccag ctggggtccc agg                                               23


<210> 550
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 550
gggggacagg ggcccagctg ggg                                               23


<210> 551
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 551
agggggacag gggcccagct ggg                                               23


<210> 552
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 552
aagggggaca ggggcccagc tgg                                               23


<210> 553
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 553
agctgggccc ctgtccccct tgg                                               23


<210> 554
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 554
gctgggcccc tgtccccctt ggg                                               23


<210> 555
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 555
ctgggcccct gtcccccttg ggg                                               23


<210> 556
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 556
cccctgtccc ccttggggcc tgg                                               23


<210> 557
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 557
ccaggcccca agggggacag ggg                                               23


<210> 558
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 558
gccaggcccc aagggggaca ggg                                               23


<210> 559
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 559
tgccaggccc caagggggac agg                                               23


<210> 560
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 560
aggactgcca ggccccaagg ggg                                               23


<210> 561
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 561
caggactgcc aggccccaag ggg                                               23


<210> 562
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 562
cccttggggc ctggcagtcc tgg                                               23


<210> 563
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 563
ccaggactgc caggccccaa ggg                                               23


<210> 564
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 564
gccaggactg ccaggcccca agg                                               23


<210> 565
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 565
tatgggatgc caggactgcc agg                                               23


<210> 566
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 566
tcctggcatc ccatagccag tgg                                               23


<210> 567
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 567
cctggcatcc catagccagt ggg                                               23


<210> 568
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 568
cccactggct atgggatgcc agg                                               23


<210> 569
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 569
ctggcatccc atagccagtg ggg                                               23


<210> 570
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 570
tgataggccc cactggctat ggg                                               23


<210> 571
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 571
ctgataggcc ccactggcta tgg                                               23


<210> 572
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 572
ccagtggggc ctatcagccc agg                                               23


<210> 573
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 573
cctgggctga taggccccac tgg                                               23


<210> 574
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 574
cagtggggcc tatcagccca ggg                                               23


<210> 575
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 575
agtggggcct atcagcccag ggg                                               23


<210> 576
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 576
gtggggccta tcagcccagg ggg                                               23


<210> 577
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 577
tggggcctat cagcccaggg ggg                                               23


<210> 578
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 578
cggggccccc ctgggctgat agg                                               23


<210> 579
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 579
ctatcagccc aggggggccc cgg                                               23


<210> 580
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 580
tatcagccca ggggggcccc ggg                                               23


<210> 581
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 581
cagggacccg gggcccccct ggg                                               23


<210> 582
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 582
ccaggggggc cccgggtccc tgg                                               23


<210> 583
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 583
ccagggaccc ggggcccccc tgg                                               23


<210> 584
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 584
aaaggggagc cagggacccg ggg                                               23


<210> 585
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 585
caaaggggag ccagggaccc ggg                                               23


<210> 586
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 586
ccgggtccct ggctcccctt tgg                                               23


<210> 587
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 587
ccaaagggga gccagggacc cgg                                               23


<210> 588
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 588
caggggccaa aggggagcca ggg                                               23


<210> 589
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 589
tcaggggcca aaggggagcc agg                                               23


<210> 590
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 590
ggctcccctt tggcccctga tgg                                               23


<210> 591
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 591
gctccccttt ggcccctgat ggg                                               23


<210> 592
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 592
gggcccatca ggggccaaag ggg                                               23


<210> 593
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 593
agggcccatc aggggccaaa ggg                                               23


<210> 594
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 594
cagggcccat caggggccaa agg                                               23


<210> 595
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 595
ttggcccctg atgggccctg tgg                                               23


<210> 596
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 596
aggaccacag ggcccatcag ggg                                               23


<210> 597
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 597
caggaccaca gggcccatca ggg                                               23


<210> 598
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 598
cctgatgggc cctgtggtcc tgg                                               23


<210> 599
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 599
ccaggaccac agggcccatc agg                                               23


<210> 600
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 600
gcagggttgc caggaccaca ggg                                               23


<210> 601
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 601
agcagggttg ccaggaccac agg                                               23


<210> 602
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 602
cctggcaacc ctgctgcccc tgg                                               23


<210> 603
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 603
ccaggggcag cagggttgcc agg                                               23


<210> 604
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 604
ctggcaaccc tgctgcccct ggg                                               23


<210> 605
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 605
tgggagtccc aggggcagca ggg                                               23


<210> 606
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 606
gtgggagtcc caggggcagc agg                                               23


<210> 607
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 607
agacggtgtg ggagtcccag ggg                                               23


<210> 608
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 608
tagacggtgt gggagtccca ggg                                               23


<210> 609
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 609
gtagacggtg tgggagtccc agg                                               23


<210> 610
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 610
actcccacac cgtctactcc agg                                               23


<210> 611
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 611
cccacaccgt ctactccagg agg                                               23


<210> 612
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 612
cctcctggag tagacggtgt ggg                                               23


<210> 613
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 613
acctcctgga gtagacggtg tgg                                               23


<210> 614
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 614
aaaggacctc ctggagtaga cgg                                               23


<210> 615
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 615
tctactccag gaggtccttt tgg                                               23


<210> 616
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 616
ctactccagg aggtcctttt ggg                                               23


<210> 617
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 617
gtgggcccaa aaggacctcc tgg                                               23


<210> 618
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 618
ccttttgggc ccacagctcc tgg                                               23


<210> 619
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 619
ccaggagctg tgggcccaaa agg                                               23


<210> 620
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 620
aggggggagc caggagctgt ggg                                               23


<210> 621
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 621
caggggggag ccaggagctg tgg                                               23


<210> 622
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 622
cacagctcct ggctcccccc tgg                                               23


<210> 623
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 623
acagctcctg gctcccccct ggg                                               23


<210> 624
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 624
cagctcctgg ctcccccctg ggg                                               23


<210> 625
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 625
cctggctccc ccctggggcc tgg                                               23


<210> 626
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 626
ccaggcccca ggggggagcc agg                                               23


<210> 627
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 627
tggagttcca ggccccaggg ggg                                               23


<210> 628
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 628
ctggagttcc aggccccagg ggg                                               23


<210> 629
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 629
cccctggggc ctggaactcc agg                                               23


<210> 630
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 630
cctggagttc caggccccag ggg                                               23


<210> 631
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 631
tcctggagtt ccaggcccca ggg                                               23


<210> 632
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 632
ctcctggagt tccaggcccc agg                                               23


<210> 633
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 633
ctggggcctg gaactccagg agg                                               23


<210> 634
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 634
tctgggcctc ctggagttcc agg                                               23


<210> 635
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 635
aagggtgagt ctgggcctcc tgg                                               23


<210> 636
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 636
caggagacaa gggtgagtct ggg                                               23


<210> 637
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 637
ccagactcac ccttgtctcc tgg                                               23


<210> 638
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 638
ccaggagaca agggtgagtc tgg                                               23


<210> 639
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 639
cagactcacc cttgtctcct ggg                                               23


<210> 640
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 640
agactcaccc ttgtctcctg ggg                                               23


<210> 641
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 641
cccttgtctc ctggggcccc agg                                               23


<210> 642
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 642
cctggggccc caggagacaa ggg                                               23


<210> 643
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 643
tcctggggcc ccaggagaca agg                                               23


<210> 644
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 644
gatgggcttc ctggggcccc agg                                               23


<210> 645
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 645
tggtttggat gggcttcctg ggg                                               23


<210> 646
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 646
ctggtttgga tgggcttcct ggg                                               23


<210> 647
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 647
ccaggaagcc catccaaacc agg                                               23


<210> 648
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 648
cctggtttgg atgggcttcc tgg                                               23


<210> 649
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 649
taggcaaacc tggtttggat ggg                                               23


<210> 650
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 650
ttaggcaaac ctggtttgga tgg                                               23


<210> 651
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 651
tggcttaggc aaacctggtt tgg                                               23


<210> 652
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 652
ccaggtttgc ctaagccagc tgg                                               23


<210> 653
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 653
ccagctggct taggcaaacc tgg                                               23


<210> 654
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 654
ttgcctaagc cagctggacc agg                                               23


<210> 655
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 655
tgcctaagcc agctggacca ggg                                               23


<210> 656
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 656
ctccctggtc cagctggctt agg                                               23


<210> 657
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 657
ctaagccagc tggaccaggg agg                                               23


<210> 658
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 658
gccagctgga ccagggaggc cgg                                               23


<210> 659
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 659
ccagctggac cagggaggcc ggg                                               23


<210> 660
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 660
cccggcctcc ctggtccagc tgg                                               23


<210> 661
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 661
cagctggacc agggaggccg ggg                                               23


<210> 662
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 662
agctggacca gggaggccgg ggg                                               23


<210> 663
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 663
gctggaccag ggaggccggg ggg                                               23


<210> 664
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 664
ctggaccagg gaggccgggg ggg                                               23


<210> 665
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 665
accagggagg ccgggggggc cgg                                               23


<210> 666
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 666
ccagggaggc cgggggggcc ggg                                               23


<210> 667
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 667
cccggccccc ccggcctccc tgg                                               23


<210> 668
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 668
cagggaggcc gggggggccg ggg                                               23


<210> 669
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 669
agggaggccg ggggggccgg ggg                                               23


<210> 670
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 670
gggggtgccc ccggcccccc cgg                                               23


<210> 671
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 671
ccgggggcac ccccctgccc tgg                                               23


<210> 672
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 672
ccagggcagg ggggtgcccc cgg                                               23


<210> 673
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 673
cgggggcacc cccctgccct ggg                                               23


<210> 674
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 674
gggggcaccc ccctgccctg ggg                                               23


<210> 675
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 675
cccccctgcc ctggggcccc agg                                               23


<210> 676
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 676
cctggggccc cagggcaggg ggg                                               23


<210> 677
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 677
gcctggggcc ccagggcagg ggg                                               23


<210> 678
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 678
tgcctggggc cccagggcag ggg                                               23


<210> 679
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 679
ctgcctgggg ccccagggca ggg                                               23


<210> 680
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 680
gctgcctggg gccccagggc agg                                               23


<210> 681
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 681
ccctggggcc ccaggcagcc cgg                                               23


<210> 682
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 682
ccgggctgcc tggggcccca ggg                                               23


<210> 683
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 683
cctggggccc caggcagccc ggg                                               23


<210> 684
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 684
cccgggctgc ctggggcccc agg                                               23


<210> 685
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 685
gggccccagg cagcccgggc tgg                                               23


<210> 686
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 686
gggccagccc gggctgcctg ggg                                               23


<210> 687
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 687
tgggccagcc cgggctgcct ggg                                               23


<210> 688
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 688
gtgggccagc ccgggctgcc tgg                                               23


<210> 689
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 689
ataatggagt gggccagccc ggg                                               23


<210> 690
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 690
gataatggag tgggccagcc cgg                                               23


<210> 691
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 691
ctcaaggggg ataatggagt ggg                                               23


<210> 692
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 692
ccactccatt atcccccttg agg                                               23


<210> 693
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 693
cctcaagggg gataatggag tgg                                               23


<210> 694
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 694
cgaggcctca agggggataa tgg                                               23


<210> 695
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 695
aggtgatcga ggcctcaagg ggg                                               23


<210> 696
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 696
caggtgatcg aggcctcaag ggg                                               23


<210> 697
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 697
cccttgaggc ctcgatcacc tgg                                               23


<210> 698
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 698
ccaggtgatc gaggcctcaa ggg                                               23


<210> 699
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 699
ccttgaggcc tcgatcacct ggg                                               23


<210> 700
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 700
cccaggtgat cgaggcctca agg                                               23


<210> 701
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 701
cttgaggcct cgatcacctg ggg                                               23


<210> 702
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 702
ttgaggcctc gatcacctgg ggg                                               23


<210> 703
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 703
cctcgatcac ctgggggccc agg                                               23


<210> 704
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 704
cctgggcccc caggtgatcg agg                                               23


<210> 705
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 705
cagggggagc ctgggccccc agg                                               23


<210> 706
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 706
ctgggggccc aggctccccc tgg                                               23


<210> 707
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 707
tgggggccca ggctccccct ggg                                               23


<210> 708
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 708
gggggcccag gctccccctg ggg                                               23


<210> 709
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 709
cagggcccca gggggagcct ggg                                               23


<210> 710
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 710
ccaggctccc cctggggccc tgg                                               23


<210> 711
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 711
ccagggcccc agggggagcc tgg                                               23


<210> 712
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 712
gggggaacca gggccccagg ggg                                               23


<210> 713
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 713
agggggaacc agggccccag ggg                                               23


<210> 714
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 714
cagggggaac cagggcccca ggg                                               23


<210> 715
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 715
cctggggccc tggttccccc tgg                                               23


<210> 716
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 716
ccagggggaa ccagggcccc agg                                               23


<210> 717
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 717
caggattcca gggggaacca ggg                                               23


<210> 718
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 718
cctggttccc cctggaatcc tgg                                               23


<210> 719
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 719
ccaggattcc agggggaacc agg                                               23


<210> 720
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 720
ctggttcccc ctggaatcct ggg                                               23


<210> 721
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 721
tggttccccc tggaatcctg ggg                                               23


<210> 722
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 722
ggttccccct ggaatcctgg ggg                                               23


<210> 723
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 723
agggccccca ggattccagg ggg                                               23


<210> 724
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 724
cagggccccc aggattccag ggg                                               23


<210> 725
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 725
ccctggaatc ctgggggccc tgg                                               23


<210> 726
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 726
ccagggcccc caggattcca ggg                                               23


<210> 727
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 727
gccagggccc ccaggattcc agg                                               23


<210> 728
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 728
caaggggtgc cagggccccc agg                                               23


<210> 729
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 729
ctgggggccc tggcacccct tgg                                               23


<210> 730
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 730
tgggggccct ggcacccctt ggg                                               23


<210> 731
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 731
caggtgccca aggggtgcca ggg                                               23


<210> 732
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 732
cctggcaccc cttgggcacc tgg                                               23


<210> 733
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 733
ccaggtgccc aaggggtgcc agg                                               23


<210> 734
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 734
tggaaaacca ggtgcccaag ggg                                               23


<210> 735
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 735
ctggaaaacc aggtgcccaa ggg                                               23


<210> 736
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 736
ccttgggcac ctggttttcc agg                                               23


<210> 737
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 737
cctggaaaac caggtgccca agg                                               23


<210> 738
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 738
cttgggcacc tggttttcca ggg                                               23


<210> 739
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 739
attactatcc ctggaaaacc agg                                               23


<210> 740
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 740
tccagggata gtaatgcctg agg                                               23


<210> 741
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 741
ccagggatag taatgcctga ggg                                               23


<210> 742
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 742
ccctcaggca ttactatccc tgg                                               23


<210> 743
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 743
cagggatagt aatgcctgag ggg                                               23


<210> 744
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 744
atagtaatgc ctgaggggcc cgg                                               23


<210> 745
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 745
tagtaatgcc tgaggggccc ggg                                               23


<210> 746
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 746
taatgcctga ggggcccggg agg                                               23


<210> 747
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 747
cctgaggggc ccgggaggcc agg                                               23


<210> 748
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 748
cctggcctcc cgggcccctc agg                                               23


<210> 749
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 749
ctgaggggcc cgggaggcca ggg                                               23


<210> 750
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 750
tgaggggccc gggaggccag ggg                                               23


<210> 751
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 751
gaggggcccg ggaggccagg ggg                                               23


<210> 752
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 752
cccgggaggc cagggggtcc tgg                                               23


<210> 753
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 753
ccaggacccc ctggcctccc ggg                                               23


<210> 754
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 754
ccgggaggcc agggggtcct ggg                                               23


<210> 755
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 755
cccaggaccc cctggcctcc cgg                                               23


<210> 756
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 756
cgggaggcca gggggtcctg ggg                                               23


<210> 757
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 757
gggaggccag ggggtcctgg ggg                                               23


<210> 758
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 758
cggggacccc caggaccccc tgg                                               23


<210> 759
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 759
cagggggtcc tgggggtccc cgg                                               23


<210> 760
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 760
ggggtcctgg gggtccccgg agg                                               23


<210> 761
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 761
cagggcctcc ggggaccccc agg                                               23


<210> 762
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 762
ctgggggtcc ccggaggccc tgg                                               23


<210> 763
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 763
cgaggggacc agggcctccg ggg                                               23


<210> 764
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 764
acgaggggac cagggcctcc ggg                                               23


<210> 765
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 765
tacgagggga ccagggcctc cgg                                               23


<210> 766
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 766
ccctggtccc ctcgtattcc tgg                                               23


<210> 767
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 767
ccaggaatac gaggggacca ggg                                               23


<210> 768
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 768
gccaggaata cgaggggacc agg                                               23


<210> 769
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 769
gggggagcca ggaatacgag ggg                                               23


<210> 770
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 770
ggggggagcc aggaatacga ggg                                               23


<210> 771
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 771
cggggggagc caggaatacg agg                                               23


<210> 772
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 772
cctggctccc cccgaagccc cgg                                               23


<210> 773
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 773
ccggggcttc ggggggagcc agg                                               23


<210> 774
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 774
agggcagccg gggcttcggg ggg                                               23


<210> 775
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 775
cagggcagcc ggggcttcgg ggg                                               23


<210> 776
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 776
ccccgaagcc ccggctgccc tgg                                               23


<210> 777
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 777
ccagggcagc cggggcttcg ggg                                               23


<210> 778
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 778
accagggcag ccggggcttc ggg                                               23


<210> 779
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 779
caccagggca gccggggctt cgg                                               23


<210> 780
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 780
cgaagccccg gctgccctgg tgg                                               23


<210> 781
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 781
tcgggccacc agggcagccg ggg                                               23


<210> 782
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 782
gtcgggccac cagggcagcc ggg                                               23


<210> 783
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 783
ggtcgggcca ccagggcagc cgg                                               23


<210> 784
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 784
ctggcaaggt cgggccacca ggg                                               23


<210> 785
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 785
cctggtggcc cgaccttgcc agg                                               23


<210> 786
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 786
cctggcaagg tcgggccacc agg                                               23


<210> 787
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 787
ctggtggccc gaccttgcca ggg                                               23


<210> 788
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 788
cagggctccc tggcaaggtc ggg                                               23


<210> 789
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 789
ccgaccttgc cagggagccc tgg                                               23


<210> 790
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 790
ccagggctcc ctggcaaggt cgg                                               23


<210> 791
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 791
cgaccttgcc agggagccct ggg                                               23


<210> 792
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 792
gaccttgcca gggagccctg ggg                                               23


<210> 793
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 793
accttgccag ggagccctgg ggg                                               23


<210> 794
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 794
tcccccaggg ctccctggca agg                                               23


<210> 795
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 795
gctggtcccc cagggctccc tgg                                               23


<210> 796
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 796
tgggcaaggc tggtccccca ggg                                               23


<210> 797
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 797
atgggcaagg ctggtccccc agg                                               23


<210> 798
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 798
ggggaccagc cttgcccatc cgg                                               23


<210> 799
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 799
gggaccagcc ttgcccatcc ggg                                               23


<210> 800
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 800
ttctcccgga tgggcaaggc tgg                                               23


<210> 801
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 801
tggcttctcc cggatgggca agg                                               23


<210> 802
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 802
ttgcccatcc gggagaagcc agg                                               23


<210> 803
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 803
tgcccatccg ggagaagcca ggg                                               23


<210> 804
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 804
gcccatccgg gagaagccag ggg                                               23


<210> 805
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 805
cccatccggg agaagccagg ggg                                               23


<210> 806
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 806
ccccctggct tctcccggat ggg                                               23


<210> 807
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 807
gccccctggc ttctcccgga tgg                                               23


<210> 808
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 808
ctgggccccc tggcttctcc cgg                                               23


<210> 809
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 809
gagaagccag ggggcccagc agg                                               23


<210> 810
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 810
agaagccagg gggcccagca ggg                                               23


<210> 811
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 811
ccagggggcc cagcagggcc agg                                               23


<210> 812
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 812
cctggccctg ctgggccccc tgg                                               23


<210> 813
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 813
atgggcagcc tggccctgct ggg                                               23


<210> 814
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 814
catgggcagc ctggccctgc tgg                                               23


<210> 815
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 815
cagcagggcc aggctgccca tgg                                               23


<210> 816
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 816
ccaggctgcc catggagtcc tgg                                               23


<210> 817
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 817
ccaggactcc atgggcagcc tgg                                               23


<210> 818
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 818
tgggaaagcc aggactccat ggg                                               23


<210> 819
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 819
atgggaaagc caggactcca tgg                                               23


<210> 820
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 820
agtcctggct ttcccatgcc tgg                                               23


<210> 821
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 821
aaaccaggca tgggaaagcc agg                                               23


<210> 822
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 822
tttcccatgc ctggttttcc tgg                                               23


<210> 823
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 823
ttcccatgcc tggttttcct ggg                                               23


<210> 824
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 824
ttcccaggaa aaccaggcat ggg                                               23


<210> 825
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 825
cttcccagga aaaccaggca tgg                                               23


<210> 826
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 826
cctggttttc ctgggaagcc agg                                               23


<210> 827
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 827
cctggcttcc caggaaaacc agg                                               23


<210> 828
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 828
ctggttttcc tgggaagcca ggg                                               23


<210> 829
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 829
tggttttcct gggaagccag ggg                                               23


<210> 830
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 830
ggttttcctg ggaagccagg ggg                                               23


<210> 831
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 831
gttttcctgg gaagccaggg ggg                                               23


<210> 832
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 832
cctgggaagc caggggggcc agg                                               23


<210> 833
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 833
cctggccccc ctggcttccc agg                                               23


<210> 834
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 834
ctgggaagcc aggggggcca ggg                                               23


<210> 835
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 835
tgggaagcca ggggggccag ggg                                               23


<210> 836
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 836
gggaagccag gggggccagg ggg                                               23


<210> 837
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 837
cggggtcccc ctggcccccc tgg                                               23


<210> 838
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 838
ggggggccag ggggaccccg agg                                               23


<210> 839
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 839
gccaggggga ccccgaggcc cgg                                               23


<210> 840
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 840
ccagggggac cccgaggccc ggg                                               23


<210> 841
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 841
cccgggcctc ggggtccccc tgg                                               23


<210> 842
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 842
ccccgaggcc cgggcttccc agg                                               23


<210> 843
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 843
cctgggaagc ccgggcctcg ggg                                               23


<210> 844
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 844
cccgaggccc gggcttccca ggg                                               23


<210> 845
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 845
ccctgggaag cccgggcctc ggg                                               23


<210> 846
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 846
ccgaggcccg ggcttcccag ggg                                               23


<210> 847
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 847
cccctgggaa gcccgggcct cgg                                               23


<210> 848
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 848
cgaggcccgg gcttcccagg ggg                                               23


<210> 849
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 849
gaggcccggg cttcccaggg ggg                                               23


<210> 850
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 850
cccgggcttc ccaggggggc cgg                                               23


<210> 851
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 851
ccggcccccc tgggaagccc ggg                                               23


<210> 852
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 852
ccgggcttcc caggggggcc ggg                                               23


<210> 853
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 853
cccggccccc ctgggaagcc cgg                                               23


<210> 854
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 854
agggagagcc cggcccccct ggg                                               23


<210> 855
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 855
aagggagagc ccggcccccc tgg                                               23


<210> 856
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 856
gggggccggg ctctcccttc agg                                               23


<210> 857
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 857
atggacctga agggagagcc cgg                                               23


<210> 858
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 858
ggctctccct tcaggtccat cgg                                               23


<210> 859
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 859
ctgctgccga tggacctgaa ggg                                               23


<210> 860
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 860
gctgctgccg atggacctga agg                                               23


<210> 861
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 861
ttcaggtcca tcggcagcag cgg                                               23


<210> 862
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 862
tccatcggca gcagcggtag agg                                               23


<210> 863
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 863
gcctctaccg ctgctgccga tgg                                               23


<210> 864
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 864
tttctgagaa agaaagagaa agg                                               23


<210> 865
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 865
ttctgagaaa gaaagagaaa ggg                                               23


<210> 866
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 866
tctgagaaag aaagagaaag ggg                                               23


<210> 867
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 867
agaaagagaa aggggcagtc agg                                               23


<210> 868
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 868
gaaagagaaa ggggcagtca ggg                                               23


<210> 869
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 869
aaagagaaag gggcagtcag ggg                                               23


<210> 870
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 870
gcagtcaggg gcctgaactg tgg                                               23


<210> 871
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 871
cagtcagggg cctgaactgt ggg                                               23


<210> 872
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 872
agtcaggggc ctgaactgtg ggg                                               23


<210> 873
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 873
ggggcctgaa ctgtggggac agg                                               23


<210> 874
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 874
gggcctgaac tgtggggaca ggg                                               23


<210> 875
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 875
ggcctgaact gtggggacag ggg                                               23


<210> 876
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 876
gtcccctgtc cccacagttc agg                                               23


<210> 877
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 877
aatgggggaa tgggtagatg ggg                                               23


<210> 878
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 878
gaatggggga atgggtagat ggg                                               23


<210> 879
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 879
ggaatggggg aatgggtaga tgg                                               23


<210> 880
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 880
tcatactgga atgggggaat ggg                                               23


<210> 881
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 881
ctcatactgg aatgggggaa tgg                                               23


<210> 882
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 882
cattccccca ttccagtatg agg                                               23


<210> 883
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 883
tgtacctcat actggaatgg ggg                                               23


<210> 884
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 884
gtgtacctca tactggaatg ggg                                               23


<210> 885
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 885
cgtgtacctc atactggaat ggg                                               23


<210> 886
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 886
ccattccagt atgaggtaca cgg                                               23


<210> 887
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 887
ccgtgtacct catactggaa tgg                                               23


<210> 888
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 888
cattccagta tgaggtacac ggg                                               23


<210> 889
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 889
ctctcccgtg tacctcatac tgg                                               23


<210> 890
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 890
cagtatgagg tacacgggag agg                                               23


<210> 891
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 891
ggtacacggg agaggaagaa tgg                                               23


<210> 892
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 892
gtacacggga gaggaagaat ggg                                               23


<210> 893
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 893
tacacgggag aggaagaatg ggg                                               23


<210> 894
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 894
gctgcccctt cctgctctca tgg                                               23


<210> 895
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 895
tcttccatga gagcaggaag ggg                                               23


<210> 896
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 896
atcttccatg agagcaggaa ggg                                               23


<210> 897
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 897
catcttccat gagagcagga agg                                               23


<210> 898
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 898
cttcctgctc tcatggaaga tgg                                               23


<210> 899
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 899
ttcctgctct catggaagat ggg                                               23


<210> 900
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 900
tcctgctctc atggaagatg ggg                                               23


<210> 901
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 901
accccatctt ccatgagagc agg                                               23


<210> 902
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 902
ctctcatgga agatggggtt tgg                                               23


<210> 903
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 903
tctcatggaa gatggggttt ggg                                               23


<210> 904
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 904
ctcatggaag atggggtttg ggg                                               23


<210> 905
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 905
tcatggaaga tggggtttgg ggg                                               23


<210> 906
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 906
tggaagatgg ggtttggggg tgg                                               23


<210> 907
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 907
atggggtttg ggggtggccc agg                                               23


<210> 908
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 908
tggggtttgg gggtggccca ggg                                               23


<210> 909
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 909
ggggtttggg ggtggcccag ggg                                               23


<210> 910
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 910
gggtggccca ggggacatct tgg                                               23


<210> 911
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 911
ggtggcccag gggacatctt ggg                                               23


<210> 912
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 912
gtggcccagg ggacatcttg ggg                                               23


<210> 913
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 913
tggcccaggg gacatcttgg ggg                                               23


<210> 914
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 914
ttgcccccaa gatgtcccct ggg                                               23


<210> 915
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 915
gttgccccca agatgtcccc tgg                                               23


<210> 916
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 916
ggggacatct tgggggcaac agg                                               23


<210> 917
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 917
gggacatctt gggggcaaca ggg                                               23


<210> 918
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 918
gcaacagggt gtcctcctta agg                                               23


<210> 919
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 919
caacagggtg tcctccttaa ggg                                               23


<210> 920
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 920
ggtgttagga gcccttaagg agg                                               23


<210> 921
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 921
ttgggtgtta ggagccctta agg                                               23


<210> 922
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 922
tcctaacacc caacctacct agg                                               23


<210> 923
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 923
gcctaggtag gttgggtgtt agg                                               23


<210> 924
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 924
aacacccaac ctacctaggc tgg                                               23


<210> 925
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 925
acacccaacc tacctaggct ggg                                               23


<210> 926
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 926
aggcccagcc taggtaggtt ggg                                               23


<210> 927
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 927
gaggcccagc ctaggtaggt tgg                                               23


<210> 928
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 928
ggaggaggcc cagcctaggt agg                                               23


<210> 929
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 929
tcatggagga ggcccagcct agg                                               23


<210> 930
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 930
ctgggcctcc tccatgagcc tgg                                               23


<210> 931
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 931
atcagccagg ctcatggagg agg                                               23


<210> 932
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 932
agaatcagcc aggctcatgg agg                                               23


<210> 933
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 933
gtgagaatca gccaggctca tgg                                               23


<210> 934
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 934
atgagaggtg agaatcagcc agg                                               23


<210> 935
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 935
tcaggtcatg cagggatgag agg                                               23


<210> 936
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 936
ctcatccctg catgacctga agg                                               23


<210> 937
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 937
atccctgcat gacctgaagg tgg                                               23


<210> 938
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 938
ctccaccttc aggtcatgca ggg                                               23


<210> 939
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 939
actccacctt caggtcatgc agg                                               23


<210> 940
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 940
tgcatgacct gaaggtggag tgg                                               23


<210> 941
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 941
ctggtggcca ctccaccttc agg                                               23


<210> 942
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 942
ctgaaggtgg agtggccacc agg                                               23


<210> 943
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 943
aaggtggagt ggccaccagg tgg                                               23


<210> 944
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 944
gggctgctgg tgccacctgg tgg                                               23


<210> 945
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 945
ggtgggctgc tggtgccacc tgg                                               23


<210> 946
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 946
cgggctctaa ggtgggctgc tgg                                               23


<210> 947
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 947
gcagcccacc ttagagcccg tgg                                               23


<210> 948
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 948
cagcccacct tagagcccgt ggg                                               23


<210> 949
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 949
gctcccacgg gctctaaggt ggg                                               23


<210> 950
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 950
tgctcccacg ggctctaagg tgg                                               23


<210> 951
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 951
ctctgctccc acgggctcta agg                                               23


<210> 952
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 952
aggtggggct ctgctcccac ggg                                               23


<210> 953
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 953
gaggtggggc tctgctccca cgg                                               23


<210> 954
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 954
aactgggaag ttgggaggtg ggg                                               23


<210> 955
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 955
gaactgggaa gttgggaggt ggg                                               23


<210> 956
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 956
tgaactggga agttgggagg tgg                                               23


<210> 957
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 957
agatgaactg ggaagttggg agg                                               23


<210> 958
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 958
gggagatgaa ctgggaagtt ggg                                               23


<210> 959
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 959
ggggagatga actgggaagt tgg                                               23


<210> 960
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 960
ttcccagttc atctccccct tgg                                               23


<210> 961
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 961
ttccaagggg gagatgaact ggg                                               23


<210> 962
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 962
cttccaaggg ggagatgaac tgg                                               23


<210> 963
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 963
gcacaggtgg tcttccaagg ggg                                               23


<210> 964
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 964
ggcacaggtg gtcttccaag ggg                                               23


<210> 965
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 965
tggcacaggt ggtcttccaa ggg                                               23


<210> 966
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 966
ctggcacagg tggtcttcca agg                                               23


<210> 967
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 967
gtgcagttag ctggcacagg tgg                                               23


<210> 968
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 968
acggtgcagt tagctggcac agg                                               23


<210> 969
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 969
ctggaaacgg tgcagttagc tgg                                               23


<210> 970
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 970
cagctaactg caccgtttcc agg                                               23


<210> 971
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 971
tgcaccgttt ccaggccctc tgg                                               23


<210> 972
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 972
gcaccgtttc caggccctct ggg                                               23


<210> 973
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 973
caccgtttcc aggccctctg ggg                                               23


<210> 974
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 974
taccccagag ggcctggaaa cgg                                               23


<210> 975
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 975
tccaggccct ctggggtatt agg                                               23


<210> 976
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 976
tcctaatacc ccagagggcc tgg                                               23


<210> 977
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 977
gtttttccta ataccccaga ggg                                               23


<210> 978
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 978
tgtttttcct aataccccag agg                                               23


<210> 979
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 979
ggtattagga aaaacactga agg                                               23


<210> 980
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 980
ttaggaaaaa cactgaaggt agg                                               23


<210> 981
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 981
aacactgaag gtaggaaaat tgg                                               23


<210> 982
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 982
actgaaggta ggaaaattgg tgg                                               23


<210> 983
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 983
ctgaaggtag gaaaattggt ggg                                               23


<210> 984
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 984
tgaaggtagg aaaattggtg ggg                                               23


<210> 985
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 985
aggaaaattg gtggggaatg agg                                               23


<210> 986
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 986
tggtggggaa tgaggagctg tgg                                               23


<210> 987
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 987
tggggaatga ggagctgtgg agg                                               23


<210> 988
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 988
ggggaatgag gagctgtgga ggg                                               23


<210> 989
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 989
ggagctgtgg agggcgcctg agg                                               23


<210> 990
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 990
gagggcgcct gaggatctga tgg                                               23


<210> 991
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 991
ctgagagcca tcagatcctc agg                                               23


<210> 992
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 992
ctgaggatct gatggctctc agg                                               23


<210> 993
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 993
tgaggatctg atggctctca ggg                                               23


<210> 994
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 994
ggatctgatg gctctcaggg agg                                               23


<210> 995
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 995
ctgatggctc tcagggaggc agg                                               23


<210> 996
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 996
tgatggctct cagggaggca ggg                                               23


<210> 997
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 997
gatggctctc agggaggcag ggg                                               23


<210> 998
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 998
tctcagggag gcaggggatt tgg                                               23


<210> 999
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 999
ctcagggagg caggggattt ggg                                               23


<210> 1000
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1000
tcagggaggc aggggatttg ggg                                               23


<210> 1001
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1001
cagggaggca ggggatttgg ggg                                               23


<210> 1002
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1002
gaggcagggg atttgggggc tgg                                               23


<210> 1003
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1003
aggcagggga tttgggggct ggg                                               23


<210> 1004
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1004
tgggggctgg gagcgatttg agg                                               23


<210> 1005
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1005
gggagcgatt tgaggcactg tgg                                               23


<210> 1006
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1006
ggagcgattt gaggcactgt ggg                                               23


<210> 1007
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1007
gagcgatttg aggcactgtg ggg                                               23


<210> 1008
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1008
atttgaggca ctgtggggtg agg                                               23


<210> 1009
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1009
tgaggcactg tggggtgagg agg                                               23


<210> 1010
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1010
gggtgaggag gctctcaccc agg                                               23


<210> 1011
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1011
ggaggctctc acccaggtac tgg                                               23


<210> 1012
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1012
gagggcaaag gccagtacct ggg                                               23


<210> 1013
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1013
tgagggcaaa ggccagtacc tgg                                               23


<210> 1014
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1014
ggtactggcc tttgccctca cgg                                               23


<210> 1015
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1015
ctggcctttg ccctcacgga agg                                               23


<210> 1016
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1016
tggcctttgc cctcacggaa ggg                                               23


<210> 1017
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1017
cctttgccct cacggaaggg cgg                                               23


<210> 1018
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1018
ccgcccttcc gtgagggcaa agg                                               23


<210> 1019
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1019
gtgggaccgc ccttccgtga ggg                                               23


<210> 1020
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1020
tgtgggaccg cccttccgtg agg                                               23


<210> 1021
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1021
tcacggaagg gcggtcccac agg                                               23


<210> 1022
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1022
tcccacaggt cctttctgca tgg                                               23


<210> 1023
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1023
cccacaggtc ctttctgcat ggg                                               23


<210> 1024
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1024
cccatgcaga aaggacctgt ggg                                               23


<210> 1025
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1025
gcccatgcag aaaggacctg tgg                                               23


<210> 1026
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1026
caggtccttt ctgcatgggc tgg                                               23


<210> 1027
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1027
tacatccagc ccatgcagaa agg                                               23


<210> 1028
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1028
atgggctgga tgtacttcac tgg                                               23


<210> 1029
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1029
tgggctggat gtacttcact ggg                                               23


<210> 1030
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1030
gggctggatg tacttcactg ggg                                               23


<210> 1031
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1031
ggcatagccc gccgccccac cgg                                               23


<210> 1032
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1032
ggcggggccg gtggggcggc ggg                                               23


<210> 1033
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1033
tggcggggcc ggtggggcgg cgg                                               23


<210> 1034
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1034
tggtggcggg gccggtgggg cgg                                               23


<210> 1035
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1035
ctctggtggc ggggccggtg ggg                                               23


<210> 1036
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1036
cccaccggcc ccgccaccag agg                                               23


<210> 1037
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1037
cctctggtgg cggggccggt ggg                                               23


<210> 1038
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1038
tcctctggtg gcggggccgg tgg                                               23


<210> 1039
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1039
gcgtcctctg gtggcggggc cgg                                               23


<210> 1040
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1040
gcgggcgtcc tctggtggcg ggg                                               23


<210> 1041
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1041
cgcgggcgtc ctctggtggc ggg                                               23


<210> 1042
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1042
ccgccaccag aggacgcccg cgg                                               23


<210> 1043
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1043
ccgcgggcgt cctctggtgg cgg                                               23


<210> 1044
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1044
gggccgcggg cgtcctctgg tgg                                               23


<210> 1045
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1045
tgtgggccgc gggcgtcctc tgg                                               23


<210> 1046
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1046
ggtgctgggg tgtgggccgc ggg                                               23


<210> 1047
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1047
tggtgctggg gtgtgggccg cgg                                               23


<210> 1048
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1048
tggtgctggt gctggggtgt ggg                                               23


<210> 1049
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1049
ctggtgctgg tgctggggtg tgg                                               23


<210> 1050
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1050
tgctactggt gctggtgctg ggg                                               23


<210> 1051
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1051
ctgctactgg tgctggtgct ggg                                               23


<210> 1052
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1052
gctgctactg gtgctggtgc tgg                                               23


<210> 1053
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1053
gctgctgctg ctactggtgc tgg                                               23


<210> 1054
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1054
ttcgctgctg ctgctgctac tgg                                               23


<210> 1055
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1055
gcagcagcag cagcgaagac agg                                               23


<210> 1056
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1056
cagcagcagc agcgaagaca ggg                                               23


<210> 1057
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1057
agcagcagca gcgaagacag ggg                                               23


<210> 1058
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1058
gggtgtcaga gtccccagca tgg                                               23


<210> 1059
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1059
agtccccagc atggcgtccg tgg                                               23


<210> 1060
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1060
cgtccacgga cgccatgctg ggg                                               23


<210> 1061
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1061
acgtccacgg acgccatgct ggg                                               23


<210> 1062
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1062
cacgtccacg gacgccatgc tgg                                               23


<210> 1063
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for wild type COL8A2"

<400> 1063
tcttctttgc agcacgtcca cgg                                               23


<210> 1064
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1064
cccctcaggc caggcttccc agg                                               23


<210> 1065
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1065
cctgggaagc ctggcctgag ggg                                               23


<210> 1066
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1066
ccctcaggcc aggttgccca ggg                                               23


<210> 1067
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1067
ccctgggaag cctggcctga ggg                                               23


<210> 1068
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1068
tccctgggaa gcctggcctg agg                                               23


<210> 1069
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Lys Mutation"

<400> 1069
ttggggctcc ctgggaagcc tgg                                               23


<210> 1070
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1070
cccctcaggc caggcacccc agg                                               23


<210> 1071
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1071
cctggggtgc ctggcctgag ggg                                               23


<210> 1072
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1072
ccctcaggcc aggcacccca ggg                                               23


<210> 1073
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1073
ccctggggtg cctggcctga ggg                                               23


<210> 1074
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1074
tccctggggt gcctggcctg agg                                               23


<210> 1075
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequence for COL8A2 Gln455Val Mutation"

<400> 1075
ttggggctcc ctggggtgcc tgg                                               23


<210> 1076
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1076
tgggggctcc ctgggcagcc tgg                                               23


<210> 1077
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1077
aaggtgactg ggggctccct ggg                                               23


<210> 1078
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1078
aaaggtgact gggggctccc tgg                                               23


<210> 1079
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1079
tggggcagaa aggtgactgg ggg                                               23


<210> 1080
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1080
ctggggcaga aaggtgactg ggg                                               23


<210> 1081
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1081
cccagtcacc tttctgcccc agg                                               23


<210> 1082
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1082
cctggggcag aaaggtgact ggg                                               23


<210> 1083
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1083
ccagtcacct ttctgcccca ggg                                               23


<210> 1084
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Target sequences for COL8A2 Leu450Trp Mutation"

<400> 1084
ccctggggca gaaaggtgac tgg                                               23


<210> 1085
<211> 1857
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      TCF4 intron 3 sequence with flanking exons, reverse 
      strand (GRCh37/hg19)"

<400> 1085
gtttgtgtga ttttgctaaa atgcatcacc aacagcgaat ggctgcctta gggacggaca       60

aagagctgag tgatttactg gatttcagtg cggtaagaaa gaacggtgga aactaacaac      120

agctgtgaaa aaaacaaaac aaaaacccaa acacttcagc tagaaaccag taggaatcta      180

aaggacagta ataattttta attggctgaa tccttggtaa atatgaaggt ctttttgaca      240

agtttttaac tataattttg tggtgtgatg gaagattcag gctttttttt ttttttgagt      300

tttattactg gccttcaatt ccctacccac tgattacccc aaataatgga atctcacccc      360

agtggaaagc aaaaatagac acccctaaaa ctaaaccacc cctaaaactt ggccatgtct      420

gaacactgag actactaata ctttgcacac tactcttcgt tttatttatt gtttttggaa      480

atggaaaata gaaaatagga gacccagttg tctctttaaa gttttaagct aatgatgctt      540

tggattggta ggacctgttc cttacatctt acctcctagt tacatctttt cctaggattc      600

ttaaaactag tatggatatg ctgagcatac attctttaga accttttgga ctgttttggt      660

aaatttcgta gtcgtaggat cagcacaaag cggaacttga cacacttgtg gagttttacg      720

gctgtacttg gtccttctcc atccctttgc ttccttttcc taaaccaagt cccagacatg      780

tcaggagaat gaattcattt ttaatgccag atgagtttgg tgtaagatgc atttgtaaag      840

caaaataaaa agaatccaca aaacacacaa ataaaatcca aaccgccttc caagtggggc      900

tctttcatgc tgctgctgct gctgctgctg ctgctgctgc tgctgctgct gctgctgctg      960

ctgctgctgc tgctgctgct gctcctcctc ctcctcctcc ttctcctcct cctcctcctc     1020

ttctagacct tcttttggag aaatggcttt cggaagtttt gccaggaaac gtagccctag     1080

gcaggcagct ttgcagcccc ctttctgctt gttgcacttt ctccattcgt tcctttgctt     1140

tttgcaggct ctgactcagg gaaggtgtgc attatccact agatacgtcg aagaagaggg     1200

aaaccaatta gggtcgaaat aaatgctgga gagagaggga gtgaaagaga gagtgagagt     1260

gagagagaga gagagtcttg cttcaaattg ctctcctgtt agagacgaaa tgagaattta     1320

gtgcaggtgg cacttttatt tttatttggg ttcacatatg acaggcaaat cctatacgag     1380

atggaaatgg acattgccac gtttatggcc aaggttttca atataaaaca aaacaacttt     1440

tttcttctcc ttggtgaaac tagtgttttt ctagagaggc tgctggcctc caacctgaat     1500

cttgataaca ttatggggac tgtgtttgtt ccaaatgtag cagtagtact gcttggccat     1560

ctaatgaacc tgaggaaaaa gaaagaacag agtgataatg ggggctgggg tgggatctgt     1620

aatgttgttt ctcttttagt tttaagttgg atggtgatgt attttactaa ataaaccctt     1680

agcataaact ctaagctgtt tggtaacagt atgaaagatc tttgaggagc tctgaaggca     1740

caagtgtctt cttttcaact gtaatatttc tttgtttctt ttagatgttt tcacctcctg     1800

tgagcagtgg gaaaaatgga ccaacttctt tggcaagtgg acattttact ggctcaa        1857


<210> 1086
<211> 100
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      sgRNA modified sequence"


<220>
<221> modified_base
<222> (1)..(3)
<223> 2'-O-Me modified natural or non-natural nucleotide 

<220>
<221> misc_feature
<222> (1)..(4)
<223> /note="PS linkage between nucleotides"

<220>
<221> modified_base
<222> (4)..(20)
<223> Any natural or non-natural nucleotide 

<220>
<221> modified_base
<222> (29)..(40)
<223> 2'-O-Me modified nucleotide 

<220>
<221> modified_base
<222> (69)..(100)
<223> 2'-O-Me modified nucleotide 

<220>
<221> misc_feature
<222> (97)..(100)
<223> /note="PS linkage between nucleotides"

<400> 1086
nnnnnnnnnn nnnnnnnnnn guuuuagagc uagaaauagc aaguuaaaau aaggcuaguc       60

cguuaucaac uugaaaaagu ggcaccgagu cggugcuuuu                            100


<210> 1087
<211> 42
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      crRNA sequence"


<220>
<221> modified_base
<222> (1)..(20)
<223> Any natural or non-natural nucleotide 

<400> 1087
nnnnnnnnnn nnnnnnnnnn guuuuagagc uaugcuguuu ug                          42


<210> 1088
<211> 74
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      trRNA sequence"

<400> 1088
aacagcauag caaguuaaaa uaaggcuagu ccguuaucaa cuugaaaaag uggcaccgag       60

ucggugcuuu uuuu                                                         74


<210> 1089
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1089
uuggcaagug gacauuuuac                                                   20


<210> 1090
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1090
uguccacuug ccaaagaagu                                                   20


<210> 1091
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1091
ggaccaacuu cuuuggcaag                                                   20


<210> 1092
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1092
gaaaaaugga ccaacuucuu                                                   20


<210> 1093
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1093
ccauuuuucc cacugcucac                                                   20


<210> 1094
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1094
ccugugagca gugggaaaaa                                                   20


<210> 1095
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1095
uuuuucccac ugcucacagg                                                   20


<210> 1096
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1096
uuucaccucc ugugagcagu                                                   20


<210> 1097
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1097
uuuucaccuc cugugagcag                                                   20


<210> 1098
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1098
agaucuuuga ggagcucuga                                                   20


<210> 1099
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1099
aacaguauga aagaucuuug                                                   20


<210> 1100
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1100
agcauaaacu cuaagcuguu                                                   20


<210> 1101
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1101
acagcuuaga guuuaugcua                                                   20


<210> 1102
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1102
cagcuuagag uuuaugcuaa                                                   20


<210> 1103
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1103
ucuuuuaguu uuaaguugga                                                   20


<210> 1104
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1104
uuucucuuuu aguuuuaagu                                                   20


<210> 1105
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1105
gugauaaugg gggcuggggu                                                   20


<210> 1106
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1106
agugauaaug ggggcugggg                                                   20


<210> 1107
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1107
cagagugaua augggggcug                                                   20


<210> 1108
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1108
acagagugau aaugggggcu                                                   20


<210> 1109
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1109
aacagaguga uaaugggggc                                                   20


<210> 1110
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1110
aaagaacaga gugauaaugg                                                   20


<210> 1111
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1111
gaaagaacag agugauaaug                                                   20


<210> 1112
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1112
agaaagaaca gagugauaau                                                   20


<210> 1113
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1113
aagaaagaac agagugauaa                                                   20


<210> 1114
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1114
ucuguucuuu cuuuuuccuc                                                   20


<210> 1115
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1115
uuuuccucag guucauuaga                                                   20


<210> 1116
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1116
uuggccaucu aaugaaccug                                                   20


<210> 1117
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1117
aauguagcag uaguacugcu                                                   20


<210> 1118
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1118
agcaguacua cugcuacauu                                                   20


<210> 1119
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1119
ugaaucuuga uaacauuaug                                                   20


<210> 1120
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1120
cugaaucuug auaacauuau                                                   20


<210> 1121
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1121
ccauaauguu aucaagauuc                                                   20


<210> 1122
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1122
ccugaaucuu gauaacauua                                                   20


<210> 1123
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1123
aauguuauca agauucaggu                                                   20


<210> 1124
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1124
guuaucaaga uucagguugg                                                   20


<210> 1125
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1125
uguuuuucua gagaggcugc                                                   20


<210> 1126
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1126
aaacuagugu uuuucuagag                                                   20


<210> 1127
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1127
gaaaaacacu aguuucacca                                                   20


<210> 1128
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1128
aacaacuuuu uucuucuccu                                                   20


<210> 1129
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1129
uuguuuuaua uugaaaaccu                                                   20


<210> 1130
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1130
gaaaaccuug gccauaaacg                                                   20


<210> 1131
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1131
cauugccacg uuuauggcca                                                   20


<210> 1132
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1132
aauggacauu gccacguuua                                                   20


<210> 1133
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1133
uguccauuuc caucucguau                                                   20


<210> 1134
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1134
aauccuauac gagauggaaa                                                   20


<210> 1135
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1135
caggcaaauc cuauacgaga                                                   20


<210> 1136
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1136
uauuuggguu cacauaugac                                                   20


<210> 1137
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1137
uggcacuuuu auuuuuauuu                                                   20


<210> 1138
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1138
guggcacuuu uauuuuuauu                                                   20


<210> 1139
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1139
aaaugagaau uuagugcagg                                                   20


<210> 1140
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1140
acgaaaugag aauuuagugc                                                   20


<210> 1141
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1141
auucucauuu cgucucuaac                                                   20


<210> 1142
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1142
aaauaaaugc uggagagaga                                                   20


<210> 1143
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1143
gaaauaaaug cuggagagag                                                   20


<210> 1144
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1144
auuagggucg aaauaaaugc                                                   20


<210> 1145
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1145
gcauuuauuu cgacccuaau                                                   20


<210> 1146
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1146
aagaagaggg aaaccaauua                                                   20


<210> 1147
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1147
gaagaagagg gaaaccaauu                                                   20


<210> 1148
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1148
acuagauacg ucgaagaaga                                                   20


<210> 1149
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1149
cacuagauac gucgaagaag                                                   20


<210> 1150
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1150
cucuucuucg acguaucuag                                                   20


<210> 1151
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1151
ugcaggcucu gacucaggga                                                   20


<210> 1152
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1152
uuuuugcagg cucugacuca                                                   20


<210> 1153
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1153
cuuuuugcag gcucugacuc                                                   20


<210> 1154
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1154
ucagagccug caaaaagcaa                                                   20


<210> 1155
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1155
uucguuccuu ugcuuuuugc                                                   20


<210> 1156
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1156
gcaaaaagca aaggaacgaa                                                   20


<210> 1157
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1157
agaaagugca acaagcagaa                                                   20


<210> 1158
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1158
gaaagugcaa caagcagaaa                                                   20


<210> 1159
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1159
aaagugcaac aagcagaaag                                                   20


<210> 1160
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1160
aagugcaaca agcagaaagg                                                   20


<210> 1161
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1161
ggcugcaaag cugccugccu                                                   20


<210> 1162
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1162
gcugcaaagc ugccugccua                                                   20


<210> 1163
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1163
caggaaacgu agcccuaggc                                                   20


<210> 1164
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1164
cugccuaggg cuacguuucc                                                   20


<210> 1165
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1165
uugccaggaa acguagcccu                                                   20


<210> 1166
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1166
uggcuuucgg aaguuuugcc                                                   20


<210> 1167
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1167
ucuuuuggag aaauggcuuu                                                   20


<210> 1168
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1168
aaagccauuu cuccaaaaga                                                   20


<210> 1169
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1169
uagaccuucu uuuggagaaa                                                   20


<210> 1170
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1170
uccaaaagaa ggucuagaag                                                   20


<210> 1171
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1171
uccucuucua gaccuucuuu                                                   20


<210> 1172
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1172
aaaagaaggu cuagaagagg                                                   20


<210> 1173
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1173
agaaggucua gaagaggagg                                                   20


<210> 1174
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1174
aggucuagaa gaggaggagg                                                   20


<210> 1175
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1175
ucuagaagag gaggaggagg                                                   20


<210> 1176
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1176
agaggaggag gaggaggaga                                                   20


<210> 1177
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1177
ggaggaggag gaggagaagg                                                   20


<210> 1178
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1178
ggaggaggag gagaaggagg                                                   20


<210> 1179
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1179
ggaggaggag aaggaggagg                                                   20


<210> 1180
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1180
ggaggagaag gaggaggagg                                                   20


<210> 1181
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1181
ggagaaggag gaggaggagg                                                   20


<210> 1182
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1182
cagcaugaaa gagccccacu                                                   20


<210> 1183
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1183
augaaagagc cccacuugga                                                   20


<210> 1184
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1184
aaagagcccc acuuggaagg                                                   20


<210> 1185
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1185
gccccacuug gaaggcgguu                                                   20


<210> 1186
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1186
uccaaaccgc cuuccaagug                                                   20


<210> 1187
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1187
auccaaaccg ccuuccaagu                                                   20


<210> 1188
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1188
aauccaaacc gccuuccaag                                                   20


<210> 1189
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1189
gauuuuauuu guguguuuug                                                   20


<210> 1190
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1190
caucuuacac caaacucauc                                                   20


<210> 1191
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1191
uuuuuaaugc cagaugaguu                                                   20


<210> 1192
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1192
auucauucuc cugacauguc                                                   20


<210> 1193
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1193
uucauucucc ugacaugucu                                                   20


<210> 1194
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1194
cuccugacau gucugggacu                                                   20


<210> 1195
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1195
aaccaagucc cagacauguc                                                   20


<210> 1196
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1196
acaugucugg gacuugguuu                                                   20


<210> 1197
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1197
cugggacuug guuuaggaaa                                                   20


<210> 1198
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1198
gguuuaggaa aaggaagcaa                                                   20


<210> 1199
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1199
guuuaggaaa aggaagcaaa                                                   20


<210> 1200
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1200
aggaaaagga agcaaaggga                                                   20


<210> 1201
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1201
aggaagcaaa gggauggaga                                                   20


<210> 1202
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1202
uggaguuuua cggcuguacu                                                   20


<210> 1203
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1203
gacacacuug uggaguuuua                                                   20


<210> 1204
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1204
agcggaacuu gacacacuug                                                   20


<210> 1205
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1205
gucguaggau cagcacaaag                                                   20


<210> 1206
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1206
uugguaaauu ucguagucgu                                                   20


<210> 1207
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1207
auuuaccaaa acaguccaaa                                                   20


<210> 1208
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1208
uagaaccuuu uggacuguuu                                                   20


<210> 1209
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1209
auacauucuu uagaaccuuu                                                   20


<210> 1210
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1210
uaggauucuu aaaacuagua                                                   20


<210> 1211
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1211
auacuaguuu uaagaauccu                                                   20


<210> 1212
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1212
uccuaggaaa agauguaacu                                                   20


<210> 1213
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1213
uccuaguuac aucuuuuccu                                                   20


<210> 1214
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1214
uaggaaaaga uguaacuagg                                                   20


<210> 1215
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1215
uaacuaggag guaagaugua                                                   20


<210> 1216
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1216
ggagguaaga uguaaggaac                                                   20


<210> 1217
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1217
uaaugaugcu uuggauuggu                                                   20


<210> 1218
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1218
aagcuaauga ugcuuuggau                                                   20


<210> 1219
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1219
guuuuaagcu aaugaugcuu                                                   20


<210> 1220
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1220
uaaaacuuua aagagacaac                                                   20


<210> 1221
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1221
aaaacuuuaa agagacaacu                                                   20


<210> 1222
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1222
ggaaauggaa aauagaaaau                                                   20


<210> 1223
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1223
uuauuuauug uuuuuggaaa                                                   20


<210> 1224
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1224
uucguuuuau uuauuguuuu                                                   20


<210> 1225
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1225
guagucucag uguucagaca                                                   20


<210> 1226
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1226
uucagacaug gccaaguuuu                                                   20


<210> 1227
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1227
ucagacaugg ccaaguuuua                                                   20


<210> 1228
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1228
cagacauggc caaguuuuag                                                   20


<210> 1229
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1229
acauggccaa guuuuagggg                                                   20


<210> 1230
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1230
acuaaaccac cccuaaaacu                                                   20


<210> 1231
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1231
uuuaggggug guuuaguuuu                                                   20


<210> 1232
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1232
uuaggggugg uuuaguuuua                                                   20


<210> 1233
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1233
uagggguggu uuaguuuuag                                                   20


<210> 1234
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1234
ugucuauuuu ugcuuuccac                                                   20


<210> 1235
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1235
gucuauuuuu gcuuuccacu                                                   20


<210> 1236
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1236
ucuauuuuug cuuuccacug                                                   20


<210> 1237
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1237
auaauggaau cucaccccag                                                   20


<210> 1238
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1238
uggggugaga uuccauuauu                                                   20


<210> 1239
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1239
ggggugagau uccauuauuu                                                   20


<210> 1240
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1240
gggugagauu ccauuauuug                                                   20


<210> 1241
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1241
ccauuauuug ggguaaucag                                                   20


<210> 1242
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1242
ccacugauua ccccaaauaa                                                   20


<210> 1243
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1243
cauuauuugg gguaaucagu                                                   20


<210> 1244
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1244
auuuggggua aucagugggu                                                   20


<210> 1245
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1245
uuugggguaa ucagugggua                                                   20


<210> 1246
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1246
aucagugggu agggaauuga                                                   20


<210> 1247
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1247
uuuuuuuuga guuuuauuac                                                   20


<210> 1248
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1248
ugugguguga uggaagauuc                                                   20


<210> 1249
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1249
acuauaauuu ugugguguga                                                   20


<210> 1250
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1250
aguuuuuaac uauaauuuug                                                   20


<210> 1251
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1251
aaagaccuuc auauuuacca                                                   20


<210> 1252
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1252
ugaauccuug guaaauauga                                                   20


<210> 1253
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1253
uuuuuaauug gcugaauccu                                                   20


<210> 1254
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1254
ggacaguaau aauuuuuaau                                                   20


<210> 1255
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1255
acuguccuuu agauuccuac                                                   20


<210> 1256
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1256
agaaaccagu aggaaucuaa                                                   20


<210> 1257
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1257
cacuucagcu agaaaccagu                                                   20


<210> 1258
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1258
ugguuucuag cugaaguguu                                                   20


<210> 1259
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1259
gguuucuagc ugaaguguuu                                                   20


<210> 1260
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1260
agugcgguaa gaaagaacgg                                                   20


<210> 1261
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1261
uucagugcgg uaagaaagaa                                                   20


<210> 1262
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1262
ugauuuacug gauuucagug                                                   20


<210> 1263
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1263
caaagagcug agugauuuac                                                   20


<210> 1264
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1264
cagcucuuug uccgucccua                                                   20


<210> 1265
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1265
gcgaauggcu gccuuaggga                                                   20


<210> 1266
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1266
aacagcgaau ggcugccuua                                                   20


<210> 1267
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1267
caacagcgaa uggcugccuu                                                   20


<210> 1268
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1268
cuaaggcagc cauucgcugu                                                   20


<210> 1269
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1269
aaugcaucac caacagcgaa                                                   20


<210> 1270
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1270
aucacacaaa ccuagaaaca                                                   20


<210> 1271
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1271
gcgguuauuu ccauguuucu                                                   20


<210> 1272
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1272
gggacuggau uuucugauug                                                   20


<210> 1273
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1273
gaaaauccag ucccaauccu                                                   20


<210> 1274
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1274
uuuucuccaa ggauugggac                                                   20


<210> 1275
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1275
uuguguuuuc uccaaggauu                                                   20


<210> 1276
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1276
auuguguuuu cuccaaggau                                                   20


<210> 1277
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1277
auccuuggag aaaacacaau                                                   20


<210> 1278
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      Guide Sequence"

<400> 1278
auccgauugu guuuucucca                                                   20


