                               SEQUENCE LISTING

<110> GENENTECH, INC.
 
<120> PHOTOCROSSLINKING PEPTIDES FOR SITE SPECIFIC CONJUGATION TO 
      FC-CONTAINING PROTEINS

<130> P34297-WO

<140>
<141>

<150> 62/777,375
<151> 2018-12-10

<160> 35    

<170> PatentIn version 3.5

<210> 1
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> source
<223> /note="C-term NH2"

<400> 1
Asp Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 2
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (1)..(1)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 2
Xaa Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 3
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (3)..(3)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 3
Asp Cys Xaa Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 4
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (5)..(5)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 4
Asp Cys Ala Trp Xaa Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 5
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (6)..(6)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 5
Asp Cys Ala Trp His Xaa Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 6
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (8)..(8)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 6
Asp Cys Ala Trp His Leu Gly Xaa Leu Val Trp Cys Thr 
1               5                   10              


<210> 7
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (9)..(9)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 7
Asp Cys Ala Trp His Leu Gly Glu Xaa Val Trp Cys Thr 
1               5                   10              


<210> 8
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (10)..(10)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 8
Asp Cys Ala Trp His Leu Gly Glu Leu Xaa Trp Cys Thr 
1               5                   10              


<210> 9
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (11)..(11)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 9
Asp Cys Ala Trp His Leu Gly Glu Leu Val Xaa Cys Thr 
1               5                   10              


<210> 10
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (13)..(13)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 10
Asp Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Xaa 
1               5                   10              


<210> 11
<211> 15
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (11)..(11)
<223> p-benzoyl-L-phenylalanine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 11
Cys Asp Cys Ala Trp His Leu Gly Glu Leu Xaa Trp Cys Thr Cys 
1               5                   10                  15  


<210> 12
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (1)..(1)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 12
Xaa Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 13
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (3)..(3)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 13
Asp Cys Xaa Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 14
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (5)..(5)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 14
Asp Cys Ala Trp Xaa Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 15
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (6)..(6)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 15
Asp Cys Ala Trp His Xaa Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 16
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (8)..(8)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 16
Asp Cys Ala Trp His Leu Gly Xaa Leu Val Trp Cys Thr 
1               5                   10              


<210> 17
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (9)..(9)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 17
Asp Cys Ala Trp His Leu Gly Glu Xaa Val Trp Cys Thr 
1               5                   10              


<210> 18
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (10)..(10)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 18
Asp Cys Ala Trp His Leu Gly Glu Leu Xaa Trp Cys Thr 
1               5                   10              


<210> 19
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (11)..(11)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 19
Asp Cys Ala Trp His Leu Gly Glu Leu Val Xaa Cys Thr 
1               5                   10              


<210> 20
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (13)..(13)
<223> Diazirinyl leucine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 20
Asp Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Xaa 
1               5                   10              


<210> 21
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (1)..(1)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 21
Xaa Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 22
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (3)..(3)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 22
Asp Cys Xaa Trp His Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 23
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (5)..(5)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 23
Asp Cys Ala Trp Xaa Leu Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 24
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (6)..(6)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 24
Asp Cys Ala Trp His Xaa Gly Glu Leu Val Trp Cys Thr 
1               5                   10              


<210> 25
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (8)..(8)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 25
Asp Cys Ala Trp His Leu Gly Xaa Leu Val Trp Cys Thr 
1               5                   10              


<210> 26
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (9)..(9)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 26
Asp Cys Ala Trp His Leu Gly Glu Xaa Val Trp Cys Thr 
1               5                   10              


<210> 27
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (10)..(10)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 27
Asp Cys Ala Trp His Leu Gly Glu Leu Xaa Trp Cys Thr 
1               5                   10              


<210> 28
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (11)..(11)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 28
Asp Cys Ala Trp His Leu Gly Glu Leu Val Xaa Cys Thr 
1               5                   10              


<210> 29
<211> 13
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> source
<223> /note="N-term Ac"

<220>
<221> MOD_RES
<222> (13)..(13)
<223> 3-trifluoromethyl-3-phenyldiazarine 

<220>
<221> source
<223> /note="C-term NH2"

<400> 29
Asp Cys Ala Trp His Leu Gly Glu Leu Val Trp Cys Xaa 
1               5                   10              


<210> 30
<211> 23
<212> PRT
<213> Unknown

<220>
<221> source
<223> /note="Description of Unknown: 
      tryptic peptide"

<400> 30
Trp Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met His Glu Ala Leu 
1               5                   10                  15      


His Asn His Tyr Thr Gln Lys 
            20              


<210> 31
<211> 7
<212> PRT
<213> Unknown

<220>
<221> source
<223> /note="Description of Unknown: 
      tryptic peptide"

<400> 31
Asp Thr Leu Met Ile Ser Arg 
1               5           


<210> 32
<211> 16
<212> PRT
<213> Homo sapiens

<400> 32
Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val 
1               5                   10                  15      


<210> 33
<211> 16
<212> PRT
<213> Homo sapiens

<400> 33
Asp Thr Leu Tyr Ile Thr Arg Glu Pro Glu Val Thr Cys Val Val Val 
1               5                   10                  15      


<210> 34
<211> 16
<212> PRT
<213> Oryctolagus cuniculus

<400> 34
Asp Thr Leu Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val 
1               5                   10                  15      


<210> 35
<211> 16
<212> PRT
<213> Mus sp.

<400> 35
Asp Val Leu Thr Ile Thr Leu Thr Pro Lys Val Thr Cys Val Val Val 
1               5                   10                  15      


