                         SEQUENCE LISTING

<110>  The University of British Columbia
       ProMIS Neurosciences, Inc.
 
<120>  ANTIBODIES TO MISFOLDED TDP-43 AND METHODS OF USE

<130>  27108-P54811PC00

<150>  62/779,904
<151>  2018-12-14

<150>  62/923,789
<151>  2019-10-21

<160>  149   

<170>  PatentIn version 3.5

<210>  1
<211>  7
<212>  PRT
<213>  Homo Sapiens

<400>  1

Asp Ala Gly Trp Gly Asn Leu 
1               5           


<210>  2
<211>  5
<212>  PRT
<213>  Homo Sapiens

<400>  2

Asp Ala Gly Trp Gly 
1               5   


<210>  3
<211>  6
<212>  PRT
<213>  Homo Sapiens

<400>  3

Asp Ala Gly Trp Gly Asn 
1               5       


<210>  4
<211>  5
<212>  PRT
<213>  Homo Sapiens

<400>  4

Ala Gly Trp Gly Asn 
1               5   


<210>  5
<211>  6
<212>  PRT
<213>  Homo Sapiens

<400>  5

Ala Gly Trp Gly Asn Leu 
1               5       


<210>  6
<211>  5
<212>  PRT
<213>  Homo Sapiens

<400>  6

Gly Trp Gly Asn Leu 
1               5   


<210>  7
<211>  21
<212>  PRT
<213>  Homo Sapiens

<400>  7

Glu Gly Ile Leu His Ala Pro Asp Ala Gly Trp Gly Asn Leu Val Tyr 
1               5                   10                  15      


Val Val Asn Tyr Pro 
            20      


<210>  8
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  8

Cys Asp Ala Gly Trp Gly Asn Leu 
1               5               


<210>  9
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  9

Asp Ala Gly Trp Gly Asn Leu Cys 
1               5               


<210>  10
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  10

Gly Phe Ser Leu Ser Arg Tyr Tyr 
1               5               


<210>  11
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  11

Ile Ile Pro Gly Gly Thr Thr 
1               5           


<210>  12
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  12

Ala Gly Gly Pro Thr Gly Asn Ser His Phe Thr Leu 
1               5                   10          


<210>  13
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  13

Glu Ser Val Tyr Asn Asn Asn His 
1               5               


<210>  14
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  14

Glu Ala Ser 
1           


<210>  15
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  15

Ser Gly Tyr Lys Arg Val Thr Thr Asp Gly Ile Ala 
1               5                   10          


<210>  16
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  16

Gly Phe Ser Phe Ser Ser Asn Tyr Val 
1               5                   


<210>  17
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  17

Ile Trp Phe Ala Gly Ile Val Asp Thr Thr 
1               5                   10  


<210>  18
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  18

Ala Arg Asn Pro Val Gly Ser Val Asn Leu 
1               5                   10  


<210>  19
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  19

Glu Ser Val Tyr Ser Asn Asn Arg 
1               5               


<210>  20
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  20

Tyr Ala Ser 
1           


<210>  21
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  21

Ala Gly Trp Arg Gly Ala Arg Thr Asp Gly Val Asp 
1               5                   10          


<210>  22
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  22

Gly Phe Ser Phe Ser Ser Ser Tyr Val 
1               5                   


<210>  23
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  23

Ser Asp Thr Gly Ile Asn Thr 
1               5           


<210>  24
<211>  15
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  24

Ala Arg Arg Tyr Thr Gly Asp Thr Tyr Leu Gly Asn Phe Asn Leu 
1               5                   10                  15  


<210>  25
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  25

Gln Ser Val Tyr Lys Asn Asn Tyr 
1               5               


<210>  26
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  26

Lys Ala Ser 
1           


<210>  27
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  27

Ala Gly Gly Trp Arg Ser Leu Asn Ala 
1               5                   


<210>  28
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  28

Glu Phe Ser Phe Ser Ser Arg Tyr Trp 
1               5                   


<210>  29
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  29

Ile Tyr Thr Gly Ser Ile Asp Ala Thr 
1               5                   


<210>  30
<211>  13
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  30

Val Arg Gly Ser Asp Ala Trp Gly Leu Tyr Phe Asn Leu 
1               5                   10              


<210>  31
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  31

Gln Ser Ile His Lys Asn Asn Tyr 
1               5               


<210>  32
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  32

Phe Ala Ser 
1           


<210>  33
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  33

Ala Gly Val Tyr Ser Gly Arg Ile Phe Ala 
1               5                   10  


<210>  34
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  34

Gly Phe Ser Leu Ser Ser Tyr Thr 
1               5               


<210>  35
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  35

Ile Tyr Gly Gly Ile Gly Ser Thr 
1               5               


<210>  36
<211>  5
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  36

Gly Arg Gly Asp Ile 
1               5   


<210>  37
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  37

Gln Ser Val Tyr Lys Asn Arg 
1               5           


<210>  38
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  38

Gly Ala Ser 
1           


<210>  39
<211>  13
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  39

Leu Gly Asn Tyr Asp Cys Ser Ser Val Asp Cys Gly Ala 
1               5                   10              


<210>  40
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  40

Gly Phe Ser Phe Ser Ala Tyr Tyr 
1               5               


<210>  41
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  41

Thr Ile Pro Ile Gly Arg Thr 
1               5           


<210>  42
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  42

Ala Gly Gly Pro Thr Gly Asn Ser His Phe Thr Leu 
1               5                   10          


<210>  43
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  43

Glu Ser Val Tyr Asn Asn Asn Gln 
1               5               


<210>  44
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  44

Gln Ala Ser 
1           


<210>  45
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  45

Ala Gly Tyr Lys Ser Pro Thr Thr Asp Gly Ile Ala 
1               5                   10          


<210>  46
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  46

Gly Phe Ser Leu Ser Ser Tyr Ala 
1               5               


<210>  47
<211>  6
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  47

Ile Tyr Asn Tyr Glu Thr 
1               5       


<210>  48
<211>  11
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  48

Ala Arg Asp Ile Phe Arg Thr Asn Thr Asn Leu 
1               5                   10      


<210>  49
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  49

Gln Ser Val Tyr Lys Asn Asn Gly 
1               5               


<210>  50
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  50

Phe Thr Ser 
1           


<210>  51
<211>  13
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  51

Leu Gly Gly Tyr Asp Cys Ser Ser Arg Val Cys Gly Ala 
1               5                   10              


<210>  52
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  52

Gly Phe Thr Phe Ser Ala Tyr Tyr 
1               5               


<210>  53
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  53

Thr Ile Pro Arg Gly Ile Thr 
1               5           


<210>  54
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  54

Ala Gly Gly Pro Thr Gly Asn Ser His Phe Thr Leu 
1               5                   10          


<210>  55
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  55

Glu Ser Val Tyr Ala Asn Asn Gln 
1               5               


<210>  56
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  56

Gln Ala Ser 
1           


<210>  57
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  57

Ser Gly Tyr Val Arg Thr Thr Thr Asp Gly Ile Ala 
1               5                   10          


<210>  58
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  58

Gly Phe Ser Leu Ile Arg Tyr Tyr 
1               5               


<210>  59
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  59

Thr Ile Pro Arg Gly Ile Thr 
1               5           


<210>  60
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  60

Ala Gly Gly Pro Thr Gly Asn Ser His Phe Thr Leu 
1               5                   10          


<210>  61
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  61

Glu Ser Val Tyr Asn Asn Asn Gln 
1               5               


<210>  62
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  62

Gln Ala Ser 
1           


<210>  63
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  63

Ser Gly Tyr Lys Ser Thr Thr Thr Asp Gly Ile Ala 
1               5                   10          


<210>  64
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  64

Gly Phe Ser Phe Ser Ser Ser Tyr Val 
1               5                   


<210>  65
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  65

Ile Tyr Phe Ala Gly Ile Asp Thr Ile 
1               5                   


<210>  66
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  66

Ala Arg Asn Pro Ile Gly Ser Val Asn Leu 
1               5                   10  


<210>  67
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  67

Gln Ser Val Tyr Ser Asn Asn Arg 
1               5               


<210>  68
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  68

Tyr Leu Ser 
1           


<210>  69
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  69

Ala Gly Trp Arg Gly Ala Thr Thr Asp Gly Val Asp 
1               5                   10          


<210>  70
<211>  9
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  70

Gly Phe Ser Phe Asn Ser Asn Tyr Val 
1               5                   


<210>  71
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  71

Ile Trp Phe Ala Gly Ser Gly Asp Val Ile 
1               5                   10  


<210>  72
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  72

Ala Arg Asn Pro Val Gly Ser Val Asn Leu 
1               5                   10  


<210>  73
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  73

Glu Ser Val Tyr Ile Asn Asn Arg 
1               5               


<210>  74
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  74

Tyr Ala Ser 
1           


<210>  75
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  75

Ala Gly Trp Arg Gly Ala Thr Thr Asp Gly Ile Asp 
1               5                   10          


<210>  76
<211>  341
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  76
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcacagtct ctggattctc cctcagtagg tactacatga cctgggtccg ccaggctcca      120

gggaaggggc tggaatacat cggggtcatt attcctggtg gtaccacata ctacgcgagc      180

tgggcgaaag gccgattcac catctccaaa acctcgacca cggtggatct gagaatcacc      240

agtccgacaa ccgaggacac ggccacttat ttctgtgccg gaggtcctac tggtaacagc      300

cactttacat tgtggggcca gggcaccctg gtcaccgtct c                          341


<210>  77
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  77
gtgatgaccc agactccatc ttccaagtct gtccctgtgg gaggcacagt caccatcaat       60

tgccaggcca gtgagagtgt ttataataac aaccacttat cctggtatca gcagaaatca      120

gggcagcctc ccaagctcct gatctacgaa gcatccaaac tggaatctgg ggtcccaccg      180

cggttcaaag gcagtggatc tgggacacag ttcactctca ccatcagcga tgtggtgtgt      240

gacgatgctg ccacttacta ctgttcagga tataaacgtg ttactactga tggtattgct      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  78
<211>  353
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  78
caggagcagc tggaggagtc cgggggagac ctggtcaagc ctgagggatc cctgacactc       60

acctgcacag cctctggatt ctccttcagt agcaactacg tgatgtgctg ggtccgccag      120

gctccaggga aggggctgga gtgggtcgca tgcatttggt ttgctggtat tgttgatact      180

acttactacg cgacctgggc gaaaggccga ttcaccatct ccaaaacctc gtcgaccacg      240

gtgactctgc aaatgaccag tctgacagcc gcggacacgg ccacctattt ctgtgcgaga      300

aatcctgttg gtagtgtgaa cttgtggggc cagggcaccc tggtcaccgt ctc             353


<210>  79
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  79
gtgatgaccc agactccatc ttccaagtct gtccctgtgg gaggctcagt caccatcaat       60

tgccaggcca gtgagagtgt ttatagtaac aaccgcttat cctggtatca gcagaaacca      120

gggcagcctc ctaagctcct gatctattat gcatccactc tggaatctgg ggtcccatcg      180

cggttcaaag gcagtggatt tgggacacac ttcactctca ccatcagcgg cgcgcagtgt      240

gacgatgctg ccacttacta ctgtgcagga tggagaggtg ctaggactga tggtgtagat      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  80
<211>  359
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  80
caggagcagc tggtggagtc cgggggaggc ctggtccagc ctggggcatc cctgacactc       60

acctgcacag cctctggatt ctccttcagt agcagctacg tgatgtgctg ggtccgccag      120

gctccaggga aggggctgga atggatcaca tgcagtgata ctggtattaa cacatggtac      180

gcgagctggg cgaaaggccg attcaccatc tccaaaacct cgtcgaccac ggtgactctg      240

caaatgacca gtctgacagc cgcggacacg gccacctatt tctgtgcgag acgttatact      300

ggcgatactt atttgggaaa ctttaacttg tggggccagg gcaccctggt caccgtctc       359


<210>  81
<211>  328
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  81
gcccaagtgc tgacccagac tccagcctcg gtgtctgcag ctgtgggagg cacagtcacc       60

atcaactgcc aggccagtca gagtgtttat aagaacaact acttatcctg gtatcagcag      120

aaaccagggc agcctcccaa gctcctgatc tacaaggctt ccactctggc atctggggtc      180

ccatcgcggt tcaagggcag tggatctggg acacagttca ctctcaccat cagcgacgtg      240

cagtgtgacg atgctgccac ttactactgt gcaggcggtt ggcgtagtct aaatgctttc      300

ggcggaggga ccgaggtggt ggtcaaag                                         328


<210>  82
<211>  359
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  82
caggagcagc tggaggagtc cgggggagac ctggtcaagc ctggggcatc cctgacactc       60

acctgcacag cctctgaatt ctccttcagt agtagatact gggcatgctg ggtccgccag      120

gctccaggga aggggctgga gtggagcgca tgcatttata ctggtagtat tgatgctact      180

tactacgcga gctgggcgaa aggccgattc accatctcca aaacctcgtc gaccacggtg      240

actctgcaag tgaccagtct gacagccgcg gacacggcca cctatttctg tgtgaggggg      300

agtgatgcct ggggtctcta ctttaacttg tggggccagg gcaccctggt caccgtctc       359


<210>  83
<211>  324
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  83
tgctgaccca gactccatcc tccgtgtctg cagctgtggg aggcacagtc accgtcagtt       60

gccagtccag tcagagtatt cataagaata attacttagc ctggtatcag cagaaaccag      120

ggcagcctcc caagctcctg atctattttg catccactct ggcatctggg gtcccatcgc      180

ggttcaaagg cagtggatct gggacacagt tcactctcac catcagtgac ctggagtgtg      240

acgatgctgc cacttactac tgtgcaggcg tttatagtgg tcgtattttt gctttcggcg      300

gagggaccga ggtggtggtc aaag                                             324


<210>  84
<211>  323
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  84
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcaaagtct ctggattctc cctcagtagc tatacaatga tctgggtccg ccaggctcca      120

gggaaggggc tggagtggat cgggtacatt tatggtggta ttggtagcac atggtacgcg      180

agctgggcga aaggccgatt caccatctcc aaaacctcga ccacggtgga tctgaaaatc      240

accagtccga caaccgagga cacggccacc tatttctgtg gcagagggga catctggggc      300

cagggcaccc tggtcaccgt ctc                                              323


<210>  85
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  85
gtgctgaccc agactgcatc ccccgtgtct gcggctgtgg gaggcacagt caccatcaat       60

tgccagtcca gtcagagtgt ttataagaac cgcttatcct ggtatcagca gaaaccaggg      120

cagtctccca agcgcctgat ctatggtgca tccactctgg aatctggggt cccatcgcgg      180

ttcaaaggca gcggatctgg gacgcagttc actctcacca tcagcgacgt gcagtgtgac      240

gatgctgcca cttactactg tctaggcaat tatgattgta gtagtgttga ttgtggtgct      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  86
<211>  341
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  86
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcacagtct ctggattctc cttcagtgcc tactacatga cctgggtccg ccaggctcca      120

gggaaggggc tggaattcat cggagtcact atacctattg gccgcacgta ctacgcgagc      180

tgggcgaaag gccgattcac catctccaaa acctcgacca cggtgcatct gaaaatcacc      240

agtccgacaa ccgaggacac ggccgcttat ttctgtgccg gaggtcctac tggtaatagc      300

cactttacat tgtggggcca gggcaccctg gtcaccgtct c                          341


<210>  87
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  87
gtgatgaccc agactccatc ttccaagtct gtccctgtgg gagacacagt taccatcaat       60

tgccaggcca gtgagagtgt ttataataac aaccaattat cctggtatca gcagaaacca      120

gggcagcctc ccaagctcct gatctaccag gcatccaaac tggaatctgg ggtcccatcg      180

cggttcaaag gcagtggatc tgggacacag ttcactctca ccatcagcga tgtggtgtgt      240

gacgatgctg ccacttacta ctgtgcagga tataaaagtc ctactactga tggtattgct      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  88
<211>  335
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  88
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcacagtct ctggattctc cctcagtagc tatgcaatga gctgggtccg ccaggctcca      120

gggaaggggc tggaatggat cggattcatt tataattatg aaacatacta cgcgaactgg      180

gcgaaaggcc gattcaccat ctccaaaacc tcgacctcgg tggttctgaa aatcaccagt      240

ccgacaaccg acgacacggc cacctatttc tgtgccagag atatttttcg tactaatact      300

aacttgtggg gccagggcac cctggtcacc gtctc                                 335


<210>  89
<211>  334
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  89
gtgctgaccc agactgcatc gcccgtgtct gcagttgtgg gaagcacagt caccatcaat       60

tgccaggcca gtcagagtgt ttataagaac aacggcttat cctggtatca gcagaaacca      120

gggcagcctc ccaaaggcct gatctctttt acatcgactc tggcatctgg ggtctcatcg      180

cggttcaaag gcagtggatc tgggacacag tttactctca ccatcagcga cgtgcagtgt      240

gacgatgctg ccacttacta ctgtctaggc ggttatgatt gtagtagtcg tgtttgtggt      300

gctttcggcg gagggaccga ggtggtggtc aaag                                  334


<210>  90
<211>  341
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  90
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcaccgtct ctggattcac cttcagtgcc tactacatga gctgggtccg ccaggctcca      120

gggaaggggc tggaatacat cggagtcacc attcctagag gtatcacata ttacgcgaac      180

tgggcgaaag gccgattcac catctccaaa acctcgacca cggtggatct gagaatcacc      240

agtccgacaa ccgaggacac ggccacttat ttctgtgccg gaggtcctac tggtaatagc      300

cactttacat tgtggggcca gggcaccctg gtcaccgtct c                          341


<210>  91
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  91
gtgatgaccc agactccatc ttccaagtct gtccctgtgg gagacacagt caccatcaat       60

tgccaggcca gtgagagtgt ttatgcgaac aaccaattat cctggtatca gcagaaacaa      120

gggcagcctc ccaagctcct gatctaccag gcatccaaac tggaatctgg ggtcccatcg      180

cggttcagtg gcagtggatc tgggacacag ttcgctctca ccatcaccga cgtgcagtgt      240

gacgatgctg ccacttacta ctgttcagga tatgtgcgta ctactactga tggtattgct      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  92
<211>  341
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  92
cagtcggtgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcacagtct ctggattctc cctcattaga tactacgtga cctgggtccg ccaggctcca      120

gggaaggggc tggaatacat cggagtcact attcccaggg gtatcacata ctacgcgagc      180

tgggcgaaag gccgattcac catctccaaa acctcgacca cggtggacct gaaaatcacc      240

agtccgacaa ccgaggacac ggccacttat ttctgtgccg gaggtcctac tggtaatagc      300

cactttacat tgtggggcca gggcaccctg gtcaccgtct c                          341


<210>  93
<211>  331
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  93
gtgatgaccc agaccccatc ttccaagtct gtccctgtgg gagacacagt caccatcaat       60

tgccaggcca gtgagagtgt ttataataac aaccaattat cttggtatca gcagaaacca      120

gggcagcctc ccaagctcct gatctaccag gcatccaaac tggaatctgg ggtcccatcg      180

catttcagtg gcagtggatc tgggacacag ttcactctca ccatcagcga cgtgcagtgt      240

gacgatgctg ccacttacta ctgttcagga tataaaagta ctactactga tggtattgct      300

ttcggcggag ggaccgaggt ggtggtcaaa g                                     331


<210>  94
<211>  350
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  94
caggagcagt tggaggagtc cgggggagac ctggtcaagc ctggggcatc cctgacactc       60

acctgcaaag cctctggatt ctccttcagt agcagctacg tgatgtgctg ggtccgccag      120

gctccaggga aggggctgga gtggatcgca tgcatttatt ttgctggtat tgatactatc      180

tactacgcga gctgggcgaa aggccgattc accatctcca aaacctcgtc gaccacggtg      240

actctgcaaa tgaccagtct gacagccgcg gacacggcca cctatttctg tgcgagaaat      300

cctattggta gtgtgaattt gtggggccag ggcaccctgg tcaccgtctc                 350


<210>  95
<211>  332
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  95
cgtgatgacc cagactccat cttccaagtc tgtccctgtg ggaggcacag tcaccatcaa       60

ttgccaggcc agtcagagtg tttatagtaa caaccgctta tcctggtttc agcagaaacc      120

agggcagcct cccaagctcc tgatctatta tttatccact ctggcatctg gggtcccatc      180

gcggttcaaa ggcagtggat ctgggacaca gttcactctc accatcagcg acgtgcagtg      240

tgacgatgct gccacttact actgtgcagg atggagaggt gccactactg atggtgttga      300

tttcggcgga gggaccgagg tggtggtcaa ag                                    332


<210>  96
<211>  353
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  96
caggagcagc tggaggagtc cgggggagac ctggtcacgc ctggaggaac cctgacactc       60

acctgcaaag cctctggatt ctccttcaat agcaactacg tgatgtgctg ggtccgccag      120

gctccaggga aggggctgga gtggatcgca tgcatttggt ttgctggtag tggtgatgtt      180

atctactatg cgagctgggc gaaaggccga ttcaccatct ccaaaacctc gtcgaccacg      240

gtgactctgc aaatgaccag tctgacagcc gcggacacgg ccacccattt ctgtgcgaga      300

aatcctgttg gtagtgtgaa cttgtggggc cagggcaccc tggtcaccgt ctc             353


<210>  97
<211>  332
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  97
cgtgatgacc cagactccat cttccaagtc tgtccctgtg ggaggcacag tcaccatcaa       60

ttgccaggcc agtgagagtg tttatattaa caaccgctta tcctggtttc agcagaaacc      120

agggcaacct cccaagctcc tgatctatta tgcatccact ctggcatctg gggtcccatc      180

gcggttcaaa ggcagtggat ctgggacaca gttcactctc accatcagcg gcgtgcagtg      240

tgacgatgct gccacttact actgtgcagg atggaggggt gctactactg atggtattga      300

tttcggcgga gggaccgagg tggtggtcaa ag                                    332


<210>  98
<211>  114
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  98

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ser Arg Tyr Tyr 
            20                  25                  30          


Met Thr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Tyr Ile Gly 
        35                  40                  45              


Val Ile Ile Pro Gly Gly Thr Thr Tyr Tyr Ala Ser Trp Ala Lys Gly 
    50                  55                  60                  


Arg Phe Thr Ile Ser Lys Thr Ser Thr Thr Val Asp Leu Arg Ile Thr 
65                  70                  75                  80  


Ser Pro Thr Thr Glu Asp Thr Ala Thr Tyr Phe Cys Ala Gly Gly Pro 
                85                  90                  95      


Thr Gly Asn Ser His Phe Thr Leu Trp Gly Gln Gly Thr Leu Val Thr 
            100                 105                 110         


Val Ser 
        


<210>  99
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  99

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Gly Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Asn Asn Asn His 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Ser Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Glu Ala Ser Lys Leu Glu Ser Gly Val Pro Pro Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Val Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ser Gly Tyr Lys Arg Val Thr Thr 
                85                  90                  95      


Asp Gly Ile Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  100
<211>  118
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  100

Gln Glu Gln Leu Glu Glu Ser Gly Gly Asp Leu Val Lys Pro Glu Gly 
1               5                   10                  15      


Ser Leu Thr Leu Thr Cys Thr Ala Ser Gly Phe Ser Phe Ser Ser Asn 
            20                  25                  30          


Tyr Val Met Cys Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 
        35                  40                  45              


Val Ala Cys Ile Trp Phe Ala Gly Ile Val Asp Thr Thr Tyr Tyr Ala 
    50                  55                  60                  


Thr Trp Ala Lys Gly Arg Phe Thr Ile Ser Lys Thr Ser Ser Thr Thr 
65                  70                  75                  80  


Val Thr Leu Gln Met Thr Ser Leu Thr Ala Ala Asp Thr Ala Thr Tyr 
                85                  90                  95      


Phe Cys Ala Arg Asn Pro Val Gly Ser Val Asn Leu Trp Gly Gln Gly 
            100                 105                 110         


Thr Leu Val Thr Val Ser 
        115             


<210>  101
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  101

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Gly Ser 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Ser Asn Asn Arg 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Tyr Ala Ser Thr Leu Glu Ser Gly Val Pro Ser Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Phe Gly Thr His Phe Thr Leu Thr Ile Ser Gly Ala Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Trp Arg Gly Ala Arg Thr 
                85                  90                  95      


Asp Gly Val Asp Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  102
<211>  120
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  102

Gln Glu Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln Pro Gly Ala 
1               5                   10                  15      


Ser Leu Thr Leu Thr Cys Thr Ala Ser Gly Phe Ser Phe Ser Ser Ser 
            20                  25                  30          


Tyr Val Met Cys Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 
        35                  40                  45              


Ile Thr Cys Ser Asp Thr Gly Ile Asn Thr Trp Tyr Ala Ser Trp Ala 
    50                  55                  60                  


Lys Gly Arg Phe Thr Ile Ser Lys Thr Ser Ser Thr Thr Val Thr Leu 
65                  70                  75                  80  


Gln Met Thr Ser Leu Thr Ala Ala Asp Thr Ala Thr Tyr Phe Cys Ala 
                85                  90                  95      


Arg Arg Tyr Thr Gly Asp Thr Tyr Leu Gly Asn Phe Asn Leu Trp Gly 
            100                 105                 110         


Gln Gly Thr Leu Val Thr Val Ser 
        115                 120 


<210>  103
<211>  109
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  103

Ala Gln Val Leu Thr Gln Thr Pro Ala Ser Val Ser Ala Ala Val Gly 
1               5                   10                  15      


Gly Thr Val Thr Ile Asn Cys Gln Ala Ser Gln Ser Val Tyr Lys Asn 
            20                  25                  30          


Asn Tyr Leu Ser Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu 
        35                  40                  45              


Leu Ile Tyr Lys Ala Ser Thr Leu Ala Ser Gly Val Pro Ser Arg Phe 
    50                  55                  60                  


Lys Gly Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val 
65                  70                  75                  80  


Gln Cys Asp Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Gly Trp Arg Ser 
                85                  90                  95      


Leu Asn Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 


<210>  104
<211>  120
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  104

Gln Glu Gln Leu Glu Glu Ser Gly Gly Asp Leu Val Lys Pro Gly Ala 
1               5                   10                  15      


Ser Leu Thr Leu Thr Cys Thr Ala Ser Glu Phe Ser Phe Ser Ser Arg 
            20                  25                  30          


Tyr Trp Ala Cys Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 
        35                  40                  45              


Ser Ala Cys Ile Tyr Thr Gly Ser Ile Asp Ala Thr Tyr Tyr Ala Ser 
    50                  55                  60                  


Trp Ala Lys Gly Arg Phe Thr Ile Ser Lys Thr Ser Ser Thr Thr Val 
65                  70                  75                  80  


Thr Leu Gln Val Thr Ser Leu Thr Ala Ala Asp Thr Ala Thr Tyr Phe 
                85                  90                  95      


Cys Val Arg Gly Ser Asp Ala Trp Gly Leu Tyr Phe Asn Leu Trp Gly 
            100                 105                 110         


Gln Gly Thr Leu Val Thr Val Ser 
        115                 120 


<210>  105
<211>  107
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  105

Leu Thr Gln Thr Pro Ser Ser Val Ser Ala Ala Val Gly Gly Thr Val 
1               5                   10                  15      


Thr Val Ser Cys Gln Ser Ser Gln Ser Ile His Lys Asn Asn Tyr Leu 
            20                  25                  30          


Ala Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile Tyr 
        35                  40                  45              


Phe Ala Ser Thr Leu Ala Ser Gly Val Pro Ser Arg Phe Lys Gly Ser 
    50                  55                  60                  


Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Leu Glu Cys Asp 
65                  70                  75                  80  


Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Val Tyr Ser Gly Arg Ile Phe 
                85                  90                  95      


Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105         


<210>  106
<211>  108
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  106

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Lys Val Ser Gly Phe Ser Leu Ser Ser Tyr Thr 
            20                  25                  30          


Met Ile Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Ile Gly 
        35                  40                  45              


Tyr Ile Tyr Gly Gly Ile Gly Ser Thr Trp Tyr Ala Ser Trp Ala Lys 
    50                  55                  60                  


Gly Arg Phe Thr Ile Ser Lys Thr Ser Thr Thr Val Asp Leu Lys Ile 
65                  70                  75                  80  


Thr Ser Pro Thr Thr Glu Asp Thr Ala Thr Tyr Phe Cys Gly Arg Gly 
                85                  90                  95      


Asp Ile Trp Gly Gln Gly Thr Leu Val Thr Val Ser 
            100                 105             


<210>  107
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  107

Val Leu Thr Gln Thr Ala Ser Pro Val Ser Ala Ala Val Gly Gly Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ser Ser Gln Ser Val Tyr Lys Asn Arg Leu 
            20                  25                  30          


Ser Trp Tyr Gln Gln Lys Pro Gly Gln Ser Pro Lys Arg Leu Ile Tyr 
        35                  40                  45              


Gly Ala Ser Thr Leu Glu Ser Gly Val Pro Ser Arg Phe Lys Gly Ser 
    50                  55                  60                  


Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Gln Cys Asp 
65                  70                  75                  80  


Asp Ala Ala Thr Tyr Tyr Cys Leu Gly Asn Tyr Asp Cys Ser Ser Val 
                85                  90                  95      


Asp Cys Gly Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  108
<211>  114
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  108

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Ser Phe Ser Ala Tyr Tyr 
            20                  25                  30          


Met Thr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Phe Ile Gly 
        35                  40                  45              


Val Thr Ile Pro Ile Gly Arg Thr Tyr Tyr Ala Ser Trp Ala Lys Gly 
    50                  55                  60                  


Arg Phe Thr Ile Ser Lys Thr Ser Thr Thr Val His Leu Lys Ile Thr 
65                  70                  75                  80  


Ser Pro Thr Thr Glu Asp Thr Ala Ala Tyr Phe Cys Ala Gly Gly Pro 
                85                  90                  95      


Thr Gly Asn Ser His Phe Thr Leu Trp Gly Gln Gly Thr Leu Val Thr 
            100                 105                 110         


Val Ser 
        


<210>  109
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  109

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Asp Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Asn Asn Asn Gln 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Gln Ala Ser Lys Leu Glu Ser Gly Val Pro Ser Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Val Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Tyr Lys Ser Pro Thr Thr 
                85                  90                  95      


Asp Gly Ile Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  110
<211>  112
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  110

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ser Ser Tyr Ala 
            20                  25                  30          


Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Ile Gly 
        35                  40                  45              


Phe Ile Tyr Asn Tyr Glu Thr Tyr Tyr Ala Asn Trp Ala Lys Gly Arg 
    50                  55                  60                  


Phe Thr Ile Ser Lys Thr Ser Thr Ser Val Val Leu Lys Ile Thr Ser 
65                  70                  75                  80  


Pro Thr Thr Asp Asp Thr Ala Thr Tyr Phe Cys Ala Arg Asp Ile Phe 
                85                  90                  95      


Arg Thr Asn Thr Asn Leu Trp Gly Gln Gly Thr Leu Val Thr Val Ser 
            100                 105                 110         


<210>  111
<211>  111
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  111

Val Leu Thr Gln Thr Ala Ser Pro Val Ser Ala Val Val Gly Ser Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Gln Ser Val Tyr Lys Asn Asn Gly 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Gly Leu Ile 
        35                  40                  45              


Ser Phe Thr Ser Thr Leu Ala Ser Gly Val Ser Ser Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Leu Gly Gly Tyr Asp Cys Ser Ser 
                85                  90                  95      


Arg Val Cys Gly Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110     


<210>  112
<211>  114
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  112

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Thr Phe Ser Ala Tyr Tyr 
            20                  25                  30          


Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Tyr Ile Gly 
        35                  40                  45              


Val Thr Ile Pro Arg Gly Ile Thr Tyr Tyr Ala Asn Trp Ala Lys Gly 
    50                  55                  60                  


Arg Phe Thr Ile Ser Lys Thr Ser Thr Thr Val Asp Leu Arg Ile Thr 
65                  70                  75                  80  


Ser Pro Thr Thr Glu Asp Thr Ala Thr Tyr Phe Cys Ala Gly Gly Pro 
                85                  90                  95      


Thr Gly Asn Ser His Phe Thr Leu Trp Gly Gln Gly Thr Leu Val Thr 
            100                 105                 110         


Val Ser 
        


<210>  113
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  113

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Asp Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Ala Asn Asn Gln 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Gln Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Gln Ala Ser Lys Leu Glu Ser Gly Val Pro Ser Arg Phe Ser Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Ala Leu Thr Ile Thr Asp Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ser Gly Tyr Val Arg Thr Thr Thr 
                85                  90                  95      


Asp Gly Ile Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  114
<211>  114
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  114

Gln Ser Val Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ile Arg Tyr Tyr 
            20                  25                  30          


Val Thr Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Tyr Ile Gly 
        35                  40                  45              


Val Thr Ile Pro Arg Gly Ile Thr Tyr Tyr Ala Ser Trp Ala Lys Gly 
    50                  55                  60                  


Arg Phe Thr Ile Ser Lys Thr Ser Thr Thr Val Asp Leu Lys Ile Thr 
65                  70                  75                  80  


Ser Pro Thr Thr Glu Asp Thr Ala Thr Tyr Phe Cys Ala Gly Gly Pro 
                85                  90                  95      


Thr Gly Asn Ser His Phe Thr Leu Trp Gly Gln Gly Thr Leu Val Thr 
            100                 105                 110         


Val Ser 
        


<210>  115
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  115

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Asp Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Asn Asn Asn Gln 
            20                  25                  30          


Leu Ser Trp Tyr Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Gln Ala Ser Lys Leu Glu Ser Gly Val Pro Ser His Phe Ser Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ser Gly Tyr Lys Ser Thr Thr Thr 
                85                  90                  95      


Asp Gly Ile Ala Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  116
<211>  117
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  116

Gln Glu Gln Leu Glu Glu Ser Gly Gly Asp Leu Val Lys Pro Gly Ala 
1               5                   10                  15      


Ser Leu Thr Leu Thr Cys Lys Ala Ser Gly Phe Ser Phe Ser Ser Ser 
            20                  25                  30          


Tyr Val Met Cys Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 
        35                  40                  45              


Ile Ala Cys Ile Tyr Phe Ala Gly Ile Asp Thr Ile Tyr Tyr Ala Ser 
    50                  55                  60                  


Trp Ala Lys Gly Arg Phe Thr Ile Ser Lys Thr Ser Ser Thr Thr Val 
65                  70                  75                  80  


Thr Leu Gln Met Thr Ser Leu Thr Ala Ala Asp Thr Ala Thr Tyr Phe 
                85                  90                  95      


Cys Ala Arg Asn Pro Ile Gly Ser Val Asn Leu Trp Gly Gln Gly Thr 
            100                 105                 110         


Leu Val Thr Val Ser 
        115         


<210>  117
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  117

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Gly Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Gln Ser Val Tyr Ser Asn Asn Arg 
            20                  25                  30          


Leu Ser Trp Phe Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Tyr Leu Ser Thr Leu Ala Ser Gly Val Pro Ser Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Asp Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Trp Arg Gly Ala Thr Thr 
                85                  90                  95      


Asp Gly Val Asp Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  118
<211>  118
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  118

Gln Glu Gln Leu Glu Glu Ser Gly Gly Asp Leu Val Thr Pro Gly Gly 
1               5                   10                  15      


Thr Leu Thr Leu Thr Cys Lys Ala Ser Gly Phe Ser Phe Asn Ser Asn 
            20                  25                  30          


Tyr Val Met Cys Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp 
        35                  40                  45              


Ile Ala Cys Ile Trp Phe Ala Gly Ser Gly Asp Val Ile Tyr Tyr Ala 
    50                  55                  60                  


Ser Trp Ala Lys Gly Arg Phe Thr Ile Ser Lys Thr Ser Ser Thr Thr 
65                  70                  75                  80  


Val Thr Leu Gln Met Thr Ser Leu Thr Ala Ala Asp Thr Ala Thr His 
                85                  90                  95      


Phe Cys Ala Arg Asn Pro Val Gly Ser Val Asn Leu Trp Gly Gln Gly 
            100                 105                 110         


Thr Leu Val Thr Val Ser 
        115             


<210>  119
<211>  110
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  119

Val Met Thr Gln Thr Pro Ser Ser Lys Ser Val Pro Val Gly Gly Thr 
1               5                   10                  15      


Val Thr Ile Asn Cys Gln Ala Ser Glu Ser Val Tyr Ile Asn Asn Arg 
            20                  25                  30          


Leu Ser Trp Phe Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Tyr Ala Ser Thr Leu Ala Ser Gly Val Pro Ser Arg Phe Lys Gly 
    50                  55                  60                  


Ser Gly Ser Gly Thr Gln Phe Thr Leu Thr Ile Ser Gly Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Ala Gly Trp Arg Gly Ala Thr Thr 
                85                  90                  95      


Asp Gly Ile Asp Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105                 110 


<210>  120
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  120

Gly Phe Ser Leu Ser Ser Tyr Asn 
1               5               


<210>  121
<211>  7
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  121

Ile Gly Thr Gly Gly Ile Thr 
1               5           


<210>  122
<211>  12
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  122

Val Arg Ser Ser Gly Ser Asp Trp Trp Phe His Ile 
1               5                   10          


<210>  123
<211>  8
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  123

Gln Ser Val Tyr Asn Asn Asn Asn 
1               5               


<210>  124
<211>  3
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  124

Arg Ala Ser 
1           


<210>  125
<211>  10
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  125

Gln Gly Tyr Phe Ser Gly Phe Ile Thr Thr 
1               5                   10  


<210>  126
<211>  341
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  126
cagtcgctgg aggagtccgg gggtcgcctg gtcacgcctg ggacacccct gacactcacc       60

tgcacagtct ctggattctc cctcagtagc tacaacatgg gctgggtccg ccaggctcca      120

ggggaggggc tggagtggat cggagtcatt ggtactggtg gtatcacaca ctacgcgacc      180

tgggcaaaag gccgagtcgc catctccaga acctcgacca cggtgggtct gcgaatgacc      240

agtccgacaa ccgaggacac ggccacctat ttctgtgtca gatctagtgg tagtgattgg      300

tggtttcaca tctggggcca gggcaccctg gtcaccgtct c                          341


<210>  127
<211>  325
<212>  DNA
<213>  Oryctolagus cuniculus

<400>  127
gtgctgaccc agactacatc gcccgtgtct gcagctgtgg gaggcacagt caccatcagt       60

tgccagtcca gtcagagtgt ttataataac aacaacttag cctggtttca gcagaaacca      120

gggcagcctc ccaagctcct gatctacagg gcatccaatc tgccatctgg tgtcccatcg      180

cggttcagag gcagtggatc tgggtcacag ttcactctca caatcagcga agtacagtgt      240

gacgatgctg ccacttacta ctgtcaaggc tattttagtg gatttatcac tactttcggc      300

ggagggaccg aggtggtggt caaag                                            325


<210>  128
<211>  114
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  128

Gln Ser Leu Glu Glu Ser Gly Gly Arg Leu Val Thr Pro Gly Thr Pro 
1               5                   10                  15      


Leu Thr Leu Thr Cys Thr Val Ser Gly Phe Ser Leu Ser Ser Tyr Asn 
            20                  25                  30          


Met Gly Trp Val Arg Gln Ala Pro Gly Glu Gly Leu Glu Trp Ile Gly 
        35                  40                  45              


Val Ile Gly Thr Gly Gly Ile Thr His Tyr Ala Thr Trp Ala Lys Gly 
    50                  55                  60                  


Arg Val Ala Ile Ser Arg Thr Ser Thr Thr Val Gly Leu Arg Met Thr 
65                  70                  75                  80  


Ser Pro Thr Thr Glu Asp Thr Ala Thr Tyr Phe Cys Val Arg Ser Ser 
                85                  90                  95      


Gly Ser Asp Trp Trp Phe His Ile Trp Gly Gln Gly Thr Leu Val Thr 
            100                 105                 110         


Val Ser 
        


<210>  129
<211>  108
<212>  PRT
<213>  Oryctolagus cuniculus

<400>  129

Val Leu Thr Gln Thr Thr Ser Pro Val Ser Ala Ala Val Gly Gly Thr 
1               5                   10                  15      


Val Thr Ile Ser Cys Gln Ser Ser Gln Ser Val Tyr Asn Asn Asn Asn 
            20                  25                  30          


Leu Ala Trp Phe Gln Gln Lys Pro Gly Gln Pro Pro Lys Leu Leu Ile 
        35                  40                  45              


Tyr Arg Ala Ser Asn Leu Pro Ser Gly Val Pro Ser Arg Phe Arg Gly 
    50                  55                  60                  


Ser Gly Ser Gly Ser Gln Phe Thr Leu Thr Ile Ser Glu Val Gln Cys 
65                  70                  75                  80  


Asp Asp Ala Ala Thr Tyr Tyr Cys Gln Gly Tyr Phe Ser Gly Phe Ile 
                85                  90                  95      


Thr Thr Phe Gly Gly Gly Thr Glu Val Val Val Lys 
            100                 105             


<210>  130
<211>  8
<212>  PRT
<213>  Mus musculus

<400>  130

Gly Phe Thr Phe Ser Ser Tyr Tyr 
1               5               


<210>  131
<211>  8
<212>  PRT
<213>  Mus Musculus

<400>  131

Ile Asn Ser Asn Gly Gly Ser Thr 
1               5               


<210>  132
<211>  9
<212>  PRT
<213>  Mus Musculus

<400>  132

Val Arg Gln Asn Tyr Glu Gly Ala Tyr 
1               5                   


<210>  133
<211>  11
<212>  PRT
<213>  Mus Musculus

<400>  133

Gln Ser Ile Val His Ser Asn Gly Asn Thr Tyr 
1               5                   10      


<210>  134
<211>  3
<212>  PRT
<213>  Mus Musculus

<400>  134

Lys Val Ser 
1           


<210>  135
<211>  9
<212>  PRT
<213>  Mus Musculus

<400>  135

Phe Gln Ser Ser His Val Pro Trp Thr 
1               5                   


<210>  136
<211>  348
<212>  DNA
<213>  Mus Musculus

<400>  136
gacgtgaagc tcgtggagtc tgggggaggc ttagtgaagc ttggagggtc cctgaaactc       60

tcctgtgcag cctctggatt cactttcagt agctattaca tgtcttgggt tcgccagact      120

ccagagaaga ggctggagtt ggtcgcaacc attaatagta atggtggtag cacctactat      180

ccagacactg tgaagggccg aatcaccatc tccagagaca atgccaagaa caccctgcag      240

ttgcaaatga gcagtctgag gtctgaggac acagccttgt attactgtgt aagacaaaac      300

tacgaggggg cttactgggg ccaagggact ctggtcactg tctctgca                   348


<210>  137
<211>  336
<212>  DNA
<213>  Mus Musculus

<400>  137
gatgttttga tgacccaaac tccactctcc ctgcctgtca ctcttggaga tcaagcctcc       60

atctcttgca gatctagtca gagcattgta catagtaatg gaaacaccta tttagaatgg      120

tacctgcaga aaccaggcca gtctccaaag ctcctgatct acaaagtttc caaccgattt      180

tctggggtcc cagacaggtt cagtggcagt ggatcaggga cagatttcac actcaagatc      240

agcagagtgg aggctgagga tctgggagtt tattactgct ttcaaagttc acatgttccg      300

tggacgttcg gtggaggcac caagctggaa atcaaa                                336


<210>  138
<211>  116
<212>  PRT
<213>  Mus Musculus

<400>  138

Asp Val Lys Leu Val Glu Ser Gly Gly Gly Leu Val Lys Leu Gly Gly 
1               5                   10                  15      


Ser Leu Lys Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 
            20                  25                  30          


Tyr Met Ser Trp Val Arg Gln Thr Pro Glu Lys Arg Leu Glu Leu Val 
        35                  40                  45              


Ala Thr Ile Asn Ser Asn Gly Gly Ser Thr Tyr Tyr Pro Asp Thr Val 
    50                  55                  60                  


Lys Gly Arg Ile Thr Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Gln 
65                  70                  75                  80  


Leu Gln Met Ser Ser Leu Arg Ser Glu Asp Thr Ala Leu Tyr Tyr Cys 
                85                  90                  95      


Val Arg Gln Asn Tyr Glu Gly Ala Tyr Trp Gly Gln Gly Thr Leu Val 
            100                 105                 110         


Thr Val Ser Ala 
        115     


<210>  139
<211>  112
<212>  PRT
<213>  Mus Musculus

<400>  139

Asp Val Leu Met Thr Gln Thr Pro Leu Ser Leu Pro Val Thr Leu Gly 
1               5                   10                  15      


Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Ile Val His Ser 
            20                  25                  30          


Asn Gly Asn Thr Tyr Leu Glu Trp Tyr Leu Gln Lys Pro Gly Gln Ser 
        35                  40                  45              


Pro Lys Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 
    50                  55                  60                  


Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 
65                  70                  75                  80  


Ser Arg Val Glu Ala Glu Asp Leu Gly Val Tyr Tyr Cys Phe Gln Ser 
                85                  90                  95      


Ser His Val Pro Trp Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 
            100                 105                 110         


<210>  140
<211>  8
<212>  PRT
<213>  Mus Musculus

<400>  140

Gly Phe Thr Phe Ser Ser Tyr Tyr 
1               5               


<210>  141
<211>  8
<212>  PRT
<213>  Mus Musculus

<400>  141

Ile Asn Thr Asn Gly Gly Ser Thr 
1               5               


<210>  142
<211>  9
<212>  PRT
<213>  Mus Musculus

<400>  142

Val Arg Gln Asn Tyr Glu Gly Ala Tyr 
1               5                   


<210>  143
<211>  11
<212>  PRT
<213>  Mus Musculus

<400>  143

Gln Ser Ile Val His Ser Asn Gly Asn Thr Tyr 
1               5                   10      


<210>  144
<211>  3
<212>  PRT
<213>  Mus Musculus

<400>  144

Lys Val Ser 
1           


<210>  145
<211>  9
<212>  PRT
<213>  Mus Musculus

<400>  145

Phe Gln Ser Ser His Val Pro Trp Thr 
1               5                   


<210>  146
<211>  348
<212>  DNA
<213>  Mus Musculus

<400>  146
gacgtgaagc tcgtggagtc tgggggagac ttagtgaagc ttggagggtc cctgaaactc       60

tcctgtgcag cctctggatt cactttcagt agctattaca tgtcttgggt tcgccagact      120

ccagagaaga ggctggagtt ggtcgcagtc attaatacta atggtggtag cacctactat      180

ccagacactg tgaagggccg attcaccatc tccagagaca atgccaagaa caccctgtac      240

ctgcaaatga gcagtctgaa gtctgaggac acagccttgt attactgtgt aagacaaaac      300

tacgaggggg cttactgggg ccaagggact ctggtcactg tctctgca                   348


<210>  147
<211>  336
<212>  DNA
<213>  Mus Musculus

<400>  147
gatgttttga tgacccaaac tccactctcc ctgcctgtca gtcttggaga tcaagcctcc       60

atctcttgca gatctagtca gagcattgta catagtaatg gaaacaccta tttagaatgg      120

tacctgcaga aaccaggcca gtctccaaag ctcctgatct acaaagtttc caaccgattt      180

tctggggtcc cagacaggtt cagtggcagt ggatcaggga cagatttcac actcaagatc      240

agcagagtgg aggctgagga tctgggagtt tattactgct ttcaaagttc acatgttccg      300

tggacgttcg gtggaggcac caagctggaa atcaaa                                336


<210>  148
<211>  116
<212>  PRT
<213>  Mus Musculus

<400>  148

Asp Val Lys Leu Val Glu Ser Gly Gly Asp Leu Val Lys Leu Gly Gly 
1               5                   10                  15      


Ser Leu Lys Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 
            20                  25                  30          


Tyr Met Ser Trp Val Arg Gln Thr Pro Glu Lys Arg Leu Glu Leu Val 
        35                  40                  45              


Ala Val Ile Asn Thr Asn Gly Gly Ser Thr Tyr Tyr Pro Asp Thr Val 
    50                  55                  60                  


Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn Thr Leu Tyr 
65                  70                  75                  80  


Leu Gln Met Ser Ser Leu Lys Ser Glu Asp Thr Ala Leu Tyr Tyr Cys 
                85                  90                  95      


Val Arg Gln Asn Tyr Glu Gly Ala Tyr Trp Gly Gln Gly Thr Leu Val 
            100                 105                 110         


Thr Val Ser Ala 
        115     


<210>  149
<211>  112
<212>  PRT
<213>  Mus Musculus

<400>  149

Asp Val Leu Met Thr Gln Thr Pro Leu Ser Leu Pro Val Ser Leu Gly 
1               5                   10                  15      


Asp Gln Ala Ser Ile Ser Cys Arg Ser Ser Gln Ser Ile Val His Ser 
            20                  25                  30          


Asn Gly Asn Thr Tyr Leu Glu Trp Tyr Leu Gln Lys Pro Gly Gln Ser 
        35                  40                  45              


Pro Lys Leu Leu Ile Tyr Lys Val Ser Asn Arg Phe Ser Gly Val Pro 
    50                  55                  60                  


Asp Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr Leu Lys Ile 
65                  70                  75                  80  


Ser Arg Val Glu Ala Glu Asp Leu Gly Val Tyr Tyr Cys Phe Gln Ser 
                85                  90                  95      


Ser His Val Pro Trp Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 
            100                 105                 110         


