                               SEQUENCE LISTING

<110> INTARCIA THERAPEUTICS, INC.
 
<120> HUMAN AMYLIN ANALOG POLYPEPTIDES AND METHODS OF USE

<130> 616782: 102487-055PC 

<140>
<141>

<150> 62/744,236
<151> 2018-10-11

<160> 318   

<170> PatentIn version 3.5

<210> 1
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 1
His Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 2
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 2
Ile Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 3
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)4CO2H)

<400> 3
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 4
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 4
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ser Asn Phe Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 5
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-dpeg-dpeg-(gammaGlu)4-CO(CH2)14CH3)

<400> 5
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 6
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Leu

<400> 6
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 7
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 7
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Lys Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 8
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 8
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Lys Thr Tyr 
        35          


<210> 9
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 9
Ser Cys Asn Thr Ala Ser Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 10
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (17)..(17)
<223> Lys(gammaGlu-CO(CH2)14CH3)

<400> 10
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


Xaa Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 11
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 11
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Arg Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 12
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 12
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 13
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)3-CO(CH2)16CH3)

<400> 13
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 14
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)5-CO(CH2)14CH3)

<400> 14
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 15
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 15
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 16
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 16
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Gly Thr Tyr 
        35          


<210> 17
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 17
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 18
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)6CO2H)

<400> 18
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 19
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-dpeg-dpeg-(gammaGlu)3-CO(CH2)14CH3)

<400> 19
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 20
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 20
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Ala Thr Tyr 
        35          


<210> 21
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)4-CO(CH2)14CH3)

<400> 21
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 22
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 22
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 23
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 23
Ser Cys Ser Thr Ala Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 24
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 24
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Ile Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 25
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-dpeg-dpeg-(gammaGlu)-CO(CH2)14CH3)

<400> 25
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 26
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-dpeg-dpeg-(gammaGlu)2-CO(CH2)14CH3)

<400> 26
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 27
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-CO(CH2)14CH3)

<400> 27
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 28
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-CO(CH2)14CH3)

<400> 28
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Gln Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 29
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)3-CO(CH2)14CH3)

<400> 29
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 30
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 30
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Glu Asn Phe Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 31
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)11CO2H)

<400> 31
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 32
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 32
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 33
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 33
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ser Asn Glu Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 34
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 34
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ser Asn Glu Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 35
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Leu

<400> 35
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 36
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-CO(CH2)14CH3)

<400> 36
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 37
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 37
Ser Cys Asn Thr Ala Ser Cys Ala Thr Gln Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 38
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 38
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 39
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-Gly-CO(CH2)14CH3)

<400> 39
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 40
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 40
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr His Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 41
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 41
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 42
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(gammaGlu-CO(CH2)14CH3)

<400> 42
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 43
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 43
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 44
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 44
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 45
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 45
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 46
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Leu

<400> 46
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 47
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-CO(CH2)14CH3)

<400> 47
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 48
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(dpeg-dpeg-gammaGlu-(CO(CH2)16CO2H))

<400> 48
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Gln Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 49
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 49
Ser Cys Ser Thr Ala Thr Cys Ala Thr Gln Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 50
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Leu

<400> 50
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 51
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 51
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


Val Arg Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 52
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 52
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ser Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 53
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)3-CO(CH2)14CH3)

<400> 53
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 54
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 54
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 55
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(CO(CH2)16CO2H))

<400> 55
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 56
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-CO(CH2)16CH3)

<400> 56
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 57
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 57
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 58
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 58
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 59
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 59
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 60
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Phe

<400> 60
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 61
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 61
Ser Cys Asn Thr Ala Ser Cys Ala Thr Gln Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


His Arg Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 62
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 62
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 63
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 63
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 64
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2(CO(CH2)18CO2H))

<400> 64
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 65
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2(CO(CH2)16CO2H))

<400> 65
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 66
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)4-CO(CH2)14CH3)

<400> 66
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 67
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)3-CO(CH2)14CH3)

<400> 67
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 68
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-CO(CH2)14CH3)

<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(2(gammaGlu)-CO(CH2)14CH3)

<400> 68
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 69
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 69
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Tyr Thr Tyr 
        35          


<210> 70
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-CO(CH2)14CH3)

<400> 70
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 71
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 71
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 72
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)14CO2H))

<400> 72
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 73
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-CO(CH2)18CO2H)

<400> 73
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 74
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)10CO2H))

<400> 74
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 75
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)18CO2H)

<400> 75
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 76
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-CO(CH2)16CO2H)

<400> 76
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 77
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)3-Gly-CO(CH2)14CH3)

<400> 77
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 78
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 78
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Pro Thr Tyr 
        35          


<210> 79
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)15CO2H)

<400> 79
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 80
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-CO(CH2)15CO2H)

<400> 80
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 81
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)12CO2H)

<400> 81
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 82
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-CO(CH2)14CO2H)

<400> 82
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 83
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)16CO2H)

<400> 83
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 84
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)8CO2H)

<400> 84
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 85
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 85
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Tyr Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 86
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)14CO2H)

<400> 86
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 87
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-CO(CH2)16CO2H)

<400> 87
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 88
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-CO(CH2)14CO2H)

<400> 88
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 89
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(CO(CH2)18CO2H)

<400> 89
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 90
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)6CO2H)

<400> 90
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 91
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)5-CO(CH2)14CH3)

<400> 91
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 92
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-CO(CH2)18CO2H)

<400> 92
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 93
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(CO(CH2)16CO2H)

<400> 93
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 94
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 94
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 95
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Lys(CO(CH2)18CO2H)

<400> 95
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 96
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Lys((gammaGlu)2-dpeg-CO(CH2)18CO2H)

<400> 96
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 97
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Lys((gammaGlu)2-CO(CH2)18CO2H)

<400> 97
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 98
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Lys(dpeg-dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 98
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 99
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (17)..(17)
<223> Lys(dpeg-dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 99
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


Xaa Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 100
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Lys((gammaGlu)2-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 100
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 101
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> D-Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 101
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 102
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(dpeg-dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 102
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 103
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 103
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 104
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)3-CO(CH2)16CO2H)

<400> 104
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 105
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 105
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Gln Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 106
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-CO(CH2)16CO2H)

<400> 106
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Gln Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 107
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (13)..(13)
<223> Lys(gammaGlu-CO(CH2)14CH3)

<400> 107
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Xaa Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 108
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (8)..(8)
<223> Lys(gammaGlu-CO(CH2)14CH3)

<400> 108
Ser Cys Asn Thr Ser Thr Cys Xaa Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 109
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-CO(CH2)16CO2H)

<400> 109
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 110
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-CO(CH2)16CO2H)

<400> 110
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 111
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 111
Ser Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Tyr Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 112
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)18CO2H)

<400> 112
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 113
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(dpeg-dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 113
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 114
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-CO(CH2)18CO2H)

<400> 114
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 115
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(CO(CH2)18CO2H)

<400> 115
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 116
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-CO(CH2)18CO2H)

<400> 116
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 117
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-CO(CH2)10CO2H)

<400> 117
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 118
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-CO(CH2)6CO2H)

<400> 118
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 119
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu)-CO(CH2)18CO2H)

<400> 119
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 120
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(CO(CH2)16CO2H)

<400> 120
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 121
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (12)..(12)
<223> Lys(gammaGlu)-CO(CH2)14CH3)

<400> 121
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Xaa Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 122
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)2-dpeg-dpeg-gammaGlu-CO(CH2)14CH3)

<400> 122
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 123
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)2-CO(CH2)14CH3)

<400> 123
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 124
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-CO(CH2)20CH3)

<400> 124
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 125
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys(gammaGlu-CO(CH2)14CH3)

<400> 125
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 126
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(dpeg-dpeg-gammaGlu-CO(CH2)16CO2H)

<400> 126
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 127
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys 

<400> 127
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 128
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 128
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 129
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys 

<400> 129
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 130
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 130
Lys Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 131
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 131
Lys Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 132
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (15)..(15)
<223> Aib 

<400> 132
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Xaa Leu 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 133
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (19)..(19)
<223> Aib 

<400> 133
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val Lys Xaa Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 134
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> Aib 

<400> 134
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 135
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (17)..(17)
<223> Aib 

<400> 135
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Xaa Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 136
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> N-MeLeu 

<400> 136
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ser Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 137
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> N-MeLeu 

<400> 137
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Xaa 
1               5                   10                  15      


Val Lys Ser Ser Asn Glu Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 138
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (14)..(14)
<223> D-Asn

<220>
<221> MOD_RES
<222> (16)..(16)
<223> Lys((gammaGlu)5-(CO(CH2)14CH3)

<400> 138
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Xaa Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Gly Thr Pro 
        35          


<210> 139
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((gammaGlu)2-(CO(CH2)18CO2H)

<400> 139
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Pro 
        35          


<210> 140
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-(CO(CH2)16CO2H)

<220>
<221> MOD_RES
<222> (14)..(14)
<223> D-Asn

<400> 140
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Xaa Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Gly Thr Pro 
        35          


<210> 141
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-(CO(CH2)16CO2H)

<220>
<221> MOD_RES
<222> (14)..(14)
<223> D-Asp

<400> 141
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Xaa Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Gly Thr Pro 
        35          


<210> 142
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-(CO(CH2)16CO2H)

<220>
<221> MOD_RES
<222> (14)..(14)
<223> D-Asp

<400> 142
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Xaa Glu Leu 
1               5                   10                  15      


Arg His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Gly Thr Pro 
        35          


<210> 143
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys((gammaGlu)2-(CO(CH2)14CO2H)

<400> 143
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 144
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(acetyl)

<400> 144
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 145
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(allyloxycarbonyl)

<400> 145
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 146
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys((dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl)

<400> 146
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 147
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu)

<400> 147
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 148
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-acetyl)

<400> 148
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 149
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-trityl)

<400> 149
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 150
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-tert-butyl)

<400> 150
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 151
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-gammaGlu)

<400> 151
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 152
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-gammaGlu-acetyl)

<400> 152
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 153
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-gammaGlu-trityl)

<400> 153
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 154
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (16)..(16)
<223> D-Lys(gammaGlu-gammaGlu-tert-butyl)

<400> 154
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Xaa 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 155
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 155
Lys Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 156
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(Fmoc)

<400> 156
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 157
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu)

<400> 157
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 158
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-acetyl)

<400> 158
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 159
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-trityl)

<400> 159
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 160
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-tert-butyl)

<400> 160
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 161
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-gammaGlu)

<400> 161
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 162
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-gammaGlu-acetyl)

<400> 162
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 163
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-gammaGlu-trityl)

<400> 163
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 164
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-gammaGlu-tert-butyl)

<400> 164
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Ser Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Gln Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 165
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu)

<400> 165
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 166
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> MOD_RES
<222> (1)..(1)
<223> Lys(gammaGlu-gammaGlu)

<400> 166
Xaa Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 167

<400> 167
000


<210> 168

<400> 168
000


<210> 169

<400> 169
000


<210> 170

<400> 170
000


<210> 171

<400> 171
000


<210> 172

<400> 172
000


<210> 173

<400> 173
000


<210> 174

<400> 174
000


<210> 175

<400> 175
000


<210> 176

<400> 176
000


<210> 177

<400> 177
000


<210> 178

<400> 178
000


<210> 179

<400> 179
000


<210> 180

<400> 180
000


<210> 181

<400> 181
000


<210> 182

<400> 182
000


<210> 183

<400> 183
000


<210> 184

<400> 184
000


<210> 185

<400> 185
000


<210> 186

<400> 186
000


<210> 187

<400> 187
000


<210> 188

<400> 188
000


<210> 189

<400> 189
000


<210> 190

<400> 190
000


<210> 191

<400> 191
000


<210> 192

<400> 192
000


<210> 193

<400> 193
000


<210> 194

<400> 194
000


<210> 195

<400> 195
000


<210> 196

<400> 196
000


<210> 197

<400> 197
000


<210> 198

<400> 198
000


<210> 199
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys" or "His" or "Ile" 

<220>
<221> VARIANT
<222> (3)..(3)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (6)..(6)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (8)..(8)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (12)..(12)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (13)..(13)
<223> /replace="Ser" or "Glu" or "Lys" 

<220>
<221> VARIANT
<222> (14)..(14)
<223> /replace="D-Asn" or "D-Asp" or "Tyr" or "Gln" 	

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" or "D-Phe" or "Tyr" or "Ile" or "D-Lys" or "Lys"
       or "alpha-aminoisobutyric acid (Aib)"

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" or "Aib" or "N-methyl leucine
      (N-MeL)" or "D-Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" or "Arg" or "D-Lys" or "Lys" or "Aib" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> VARIANT
<222> (19)..(19)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (20)..(20)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (22)..(22)
<223> /replace="Glu" 

<220>
<221> VARIANT
<222> (29)..(29)
<223> /replace="Arg" or "Lys" 

<220>
<221> VARIANT
<222> (31)..(31)
<223> /replace="D-Lys" or "Asn" or "His" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="D-Glu" or "Asn" or "Lys" or "Gly" or "Ala" or "Tyr" or "Pro" 

<220>
<221> VARIANT
<222> (37)..(37)
<223> /replace="Pro" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 199
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 200
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys" or "His" or "Ile" 

<220>
<221> VARIANT
<222> (3)..(3)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (6)..(6)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (8)..(8)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (12)..(12)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (13)..(13)
<223> /replace="Ser" or "Glu" or "Lys" 

<220>
<221> VARIANT
<222> (14)..(14)
<223> /replace="D-Asn" or "D-Asp" or "Tyr" or "Gln" 	

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" or "D-Phe" or "Tyr" or "Ile" or "D-Lys" or "Lys"
       or "alpha-aminoisobutyric acid (Aib)"

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" or "Aib" or "N-methyl leucine
      (N-MeL)" or "D-Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" or "Arg" or "D-Lys" or "Lys" or "Aib" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> VARIANT
<222> (19)..(19)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (20)..(20)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (22)..(22)
<223> /replace="Glu" 

<220>
<221> VARIANT
<222> (29)..(29)
<223> /replace="Arg" or "Lys" 

<220>
<221> VARIANT
<222> (31)..(31)
<223> /replace="D-Lys" or "Asn" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="D-Glu" or "Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 200
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 201
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys" or "His" or "Ile" 

<220>
<221> VARIANT
<222> (3)..(3)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (6)..(6)
<223> /replace="Ser"

<220>
<221> VARIANT
<222> (8)..(8)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (12)..(12)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (13)..(13)
<223> /replace="Ser" or "Glu" or "Lys" 

<220>
<221> VARIANT
<222> (14)..(14)
<223> /replace="D-Asn" or "D-Asp" or "Tyr" or "Gln" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" or "D-Phe" or "Tyr" or "Ile" or "D-Lys"
      or "Lys" or "Aib" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" or "Aib" or "N-MeL" or "D-Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" or "Arg" or "D-Lys" or "Lys" or "Aib" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> VARIANT
<222> (19)..(19)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (20)..(20)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (22)..(22)
<223> /replace="Glu" 

<220>
<221> VARIANT
<222> (29)..(29)
<223> /replace="Arg" or "Lys" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 201
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 202
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys" or "Lys"  

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> VARIANT
<222> (31)..(31)
<223> /replace="Asn" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 202
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 203
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys" or "Lys"  

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 203
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 204
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 204
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 205
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 205
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 206
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 206
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 207
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 207
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 208
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser"

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys"

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 208
Lys Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 209
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys"

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser"

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 209
Lys Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 210
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys" or "His" or "Ile" 

<220>
<221> VARIANT
<222> (3)..(3)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> VARIANT
<222> (6)..(6)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (8)..(8)
<223> /replace="Lys" 

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (12)..(12)
<223> /replace="Lys 

<220>
<221> VARIANT
<222> (13)..(13)
<223> /replace="Ser" or "Glu" or "Lys" 

<220>
<221> VARIANT
<222> (14)..(14)
<223> /replace="D-Asn" or "D-Asp" or "Tyr" or "Gln" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" or "D-Phe" or "Tyr" or "Ile" or "D-Lys" or "Lys"
      or "alpha-aminoisobutyric acid (Aib)"

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="D-Lys" or "Leu" or "Aib" or "N-methyl leucine
      (N-MeL)" or "D-Leu" 

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" or "Arg" or "D-Lys" or "Lys" or "Aib" 

<220>
<221> VARIANT
<222> (18)..(18)
<223> /replace="His" or "Arg" 

<220>
<221> VARIANT
<222> (19)..(19)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (20)..(20)
<223> /replace="Aib" 

<220>
<221> VARIANT
<222> (22)..(22)
<223> /replace="Glu" 

<220>
<221> VARIANT
<222> (29)..(29)
<223> /replace="Arg" or "Lys" 

<220>
<221> VARIANT
<222> (31)..(31)
<223> /replace="D-Lys" or "Asn" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="D-Glu" or "Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 210
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Lys 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 211
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (10)..(10)
<223> /replace="Ser" 

<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys"  

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 211
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 212
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"


<220>
<221> VARIANT
<222> (15)..(15)
<223> /replace="Phe" 

<220>
<221> VARIANT
<222> (16)..(16)
<223> /replace="Lys" or "D-Lys"

<220>
<221> VARIANT
<222> (17)..(17)
<223> /replace="Val" or "Gln" 

<220>
<221> VARIANT
<222> (35)..(35)
<223> /replace="Asn" 

<220>
<221> SITE
<222> (1)..(37)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 212
Ser Cys Asn Thr Ser Thr Cys Ala Thr Gln Arg Leu Ala Asn Glu Leu 
1               5                   10                  15      


His Lys Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Lys Val 
            20                  25                  30          


Gly Ser Glu Thr Tyr 
        35          


<210> 213

<400> 213
000


<210> 214

<400> 214
000


<210> 215

<400> 215
000


<210> 216

<400> 216
000


<210> 217

<400> 217
000


<210> 218

<400> 218
000


<210> 219

<400> 219
000


<210> 220

<400> 220
000


<210> 221

<400> 221
000


<210> 222

<400> 222
000


<210> 223

<400> 223
000


<210> 224

<400> 224
000


<210> 225

<400> 225
000


<210> 226

<400> 226
000


<210> 227

<400> 227
000


<210> 228

<400> 228
000


<210> 229

<400> 229
000


<210> 230

<400> 230
000


<210> 231

<400> 231
000


<210> 232

<400> 232
000


<210> 233

<400> 233
000


<210> 234

<400> 234
000


<210> 235

<400> 235
000


<210> 236

<400> 236
000


<210> 237

<400> 237
000


<210> 238

<400> 238
000


<210> 239

<400> 239
000


<210> 240

<400> 240
000


<210> 241

<400> 241
000


<210> 242

<400> 242
000


<210> 243

<400> 243
000


<210> 244

<400> 244
000


<210> 245

<400> 245
000


<210> 246

<400> 246
000


<210> 247

<400> 247
000


<210> 248

<400> 248
000


<210> 249

<400> 249
000


<210> 250

<400> 250
000


<210> 251

<400> 251
000


<210> 252

<400> 252
000


<210> 253

<400> 253
000


<210> 254

<400> 254
000


<210> 255

<400> 255
000


<210> 256

<400> 256
000


<210> 257

<400> 257
000


<210> 258

<400> 258
000


<210> 259

<400> 259
000


<210> 260

<400> 260
000


<210> 261

<400> 261
000


<210> 262

<400> 262
000


<210> 263

<400> 263
000


<210> 264

<400> 264
000


<210> 265

<400> 265
000


<210> 266

<400> 266
000


<210> 267

<400> 267
000


<210> 268

<400> 268
000


<210> 269

<400> 269
000


<210> 270

<400> 270
000


<210> 271

<400> 271
000


<210> 272

<400> 272
000


<210> 273

<400> 273
000


<210> 274

<400> 274
000


<210> 275

<400> 275
000


<210> 276

<400> 276
000


<210> 277

<400> 277
000


<210> 278

<400> 278
000


<210> 279

<400> 279
000


<210> 280

<400> 280
000


<210> 281

<400> 281
000


<210> 282

<400> 282
000


<210> 283

<400> 283
000


<210> 284

<400> 284
000


<210> 285

<400> 285
000


<210> 286

<400> 286
000


<210> 287

<400> 287
000


<210> 288

<400> 288
000


<210> 289

<400> 289
000


<210> 290

<400> 290
000


<210> 291

<400> 291
000


<210> 292

<400> 292
000


<210> 293

<400> 293
000


<210> 294

<400> 294
000


<210> 295

<400> 295
000


<210> 296

<400> 296
000


<210> 297

<400> 297
000


<210> 298

<400> 298
000


<210> 299

<400> 299
000


<210> 300
<211> 37
<212> PRT
<213> Homo sapiens

<400> 300
Lys Cys Asn Thr Ala Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Ala Ile Leu Ser Ser Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 301
<211> 37
<212> PRT
<213> Rattus sp.

<400> 301
Lys Cys Asn Thr Ala Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val Arg Ser Ser Asn Asn Leu Gly Pro Val Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 302
<211> 37
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 302
Lys Cys Asn Thr Ala Thr Cys Ala Thr Gln Arg Leu Ala Asn Phe Leu 
1               5                   10                  15      


Val His Ser Ser Asn Asn Phe Gly Pro Ile Leu Pro Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Asn Thr Tyr 
        35          


<210> 303
<211> 32
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      polypeptide"

<400> 303
Lys Cys Asn Thr Ala Thr Cys Val Leu Gly Arg Leu Ser Gln Glu Leu 
1               5                   10                  15      


His Arg Leu Gln Thr Tyr Pro Arg Thr Asn Thr Gly Ser Asn Thr Tyr 
            20                  25                  30          


<210> 304
<211> 32
<212> PRT
<213> Homo sapiens

<400> 304
Cys Gly Asn Leu Ser Thr Cys Met Leu Gly Thr Tyr Thr Gln Asp Phe 
1               5                   10                  15      


Asn Lys Phe His Thr Phe Pro Gln Thr Ala Ile Gly Val Gly Ala Pro 
            20                  25                  30          


<210> 305
<211> 32
<212> PRT
<213> Unknown

<220>
<221> source
<223> /note="Description of Unknown: 
      salmon calcitonin"

<400> 305
Cys Ser Asn Leu Ser Thr Cys Val Leu Gly Lys Leu Ser Gln Glu Leu 
1               5                   10                  15      


His Lys Leu Gln Thr Tyr Pro Arg Thr Asn Thr Gly Ser Gly Thr Pro 
            20                  25                  30          


<210> 306
<211> 37
<212> PRT
<213> Unknown

<220>
<221> source
<223> /note="Description of Unknown: 
      beta-calcitonin-gene-related peptide"

<400> 306
Ala Cys Asn Thr Ala Thr Cys Val Thr His Arg Leu Ala Gly Leu Leu 
1               5                   10                  15      


Ser Arg Ser Gly Gly Met Val Lys Ser Asn Phe Val Pro Thr Asn Val 
            20                  25                  30          


Gly Ser Lys Ala Phe 
        35          


<210> 307
<211> 39
<212> PRT
<213> Unknown

<220>
<221> source
<223> /note="Description of Unknown: 
      exenatide sequence"

<400> 307
His Gly Glu Gly Thr Phe Thr Ser Asp Leu Ser Lys Gln Met Glu Glu 
1               5                   10                  15      


Glu Ala Val Arg Leu Phe Ile Glu Trp Leu Lys Asn Gly Gly Pro Ser 
            20                  25                  30          


Ser Gly Ala Pro Pro Pro Ser 
        35                  


<210> 308
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys" or "Lys" 

<220>
<221> VARIANT
<222> (5)..(5)
<223> /replace="Ala" 

<220>
<221> SITE
<222> (1)..(7)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 308
Ser Cys Asn Thr Ser Thr Cys 
1               5           


<210> 309
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="Lys" or "D-Lys" 

<220>
<221> SITE
<222> (1)..(7)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 309
Ser Cys Asn Thr Ser Thr Cys 
1               5           


<210> 310
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"

<400> 310
Ser Cys Asn Thr Ser Thr Cys 
1               5           


<210> 311
<211> 10
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (1)..(10)
<223> gammaGlu

<220>
<221> SITE
<222> (1)..(10)
<223> /note="This sequence may encompass 1-10 residues"

<400> 311
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 
1               5                   10  


<210> 312
<211> 11
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (1)..(10)
<223> gammaGlu

<220>
<221> SITE
<222> (1)..(10)
<223> /note="This region may encompass 1-10 residues"

<400> 312
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Gly 
1               5                   10      


<210> 313
<211> 4
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (1)..(4)
<223> gammaGlu

<400> 313
Xaa Xaa Xaa Xaa 
1               


<210> 314
<211> 5
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (1)..(5)
<223> gammaGlu

<400> 314
Xaa Xaa Xaa Xaa Xaa 
1               5   


<210> 315
<211> 4
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (1)..(3)
<223> gammaGlu

<400> 315
Xaa Xaa Xaa Gly 
1               


<210> 316
<211> 11
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"


<220>
<221> MOD_RES
<222> (2)..(11)
<223> gammaGlu

<220>
<221> SITE
<222> (2)..(11)
<223> /note="This region may encompass 1-10 residues"

<400> 316
Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 
1               5                   10      


<210> 317
<211> 4
<212> PRT
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      peptide"

<400> 317
Glu Glu Glu Glu 
1               


<210> 318
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide


<220>
<221> VARIANT
<222> (1)..(1)
<223> /replace="D-Lys" 

<220>
<221> SITE
<222> (1)..(7)
<223> /note="Variant residues given in the sequence have no 
      preference with respect to those in the annotations
      for variant positions"

<400> 318
Lys Cys Asn Thr Ser Thr Cys 
1               5           



