                         SEQUENCE LISTING

<110>  aratinga.bio TNP
 
<120>  Aptamer-Based CAR T-Cell Switch

<130>  12269-0202

<140>  PCT/IB2019/000890
<141>  2019-07-26

<150>  US 62/703689
<151>  2018-07-26

<160>  19    

<170>  PatentIn version 3.5

<210>  1
<211>  14
<212>  PRT
<213>  Saccharomyces cerevisiae

<400>  1

Asn Tyr His Leu Glu Asn Glu Val Ala Arg Leu Lys Lys Leu 
1               5                   10                  


<210>  2
<211>  15
<212>  PRT
<213>  Staphylococcus aureus

<400>  2

Glu Ser Gln Pro Asp Pro Lys Pro Asp Glu Leu His Lys Ser Ser 
1               5                   10                  15  


<210>  3
<211>  12
<212>  PRT
<213>  Hepatitis B virus

<400>  3

Pro Arg Val Arg Gly Leu Tyr Phe Pro Ala Gly Gly 
1               5                   10          


<210>  4
<211>  10
<212>  PRT
<213>  Bovine herpesvirus 1

<400>  4

Met Glu Glu Ser Lys Gly Tyr Glu Pro Pro 
1               5                   10  


<210>  5
<211>  9
<212>  PRT
<213>  Bovine herpesvirus 1

<400>  5

Asp Arg Thr Asn Asn Gln Val Lys Ala 
1               5                   


<210>  6
<211>  7
<212>  PRT
<213>  grapevine leafroll-associated virus 3

<400>  6

Ala Gln Glu Pro Pro Arg Gln 
1               5           


<210>  7
<211>  24
<212>  PRT
<213>  SARS-CoV

<400>  7

Pro Thr Asp Ser Thr Asp Asn Asn Gln Asn Gly Gly Arg Asn Gly Ala 
1               5                   10                  15      


Arg Pro Lys Gln Arg Arg Pro Gln 
            20                  


<210>  8
<211>  39
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  aptamer A10

<400>  8
gggaggacga ugcggaucag ccauguuuac gucacuccu                              39


<210>  9
<211>  43
<212>  DNA
<213>  artificial sequence

<220>
<223>  aptamer CELTIC_1s

<400>  9
tttccgggtg ggggtttggc accgggcctg gcgcagggat tcg                         43


<210>  10
<211>  40
<212>  DNA
<213>  artificial sequence

<220>
<223>  aptamer CELTIC_19s

<400>  10
taccgcgggg attggctccg ggcctggcgt cgtaatctga                             40


<210>  11
<211>  21
<212>  DNA
<213>  artificial sequence

<220>
<223>  aptamer CELTIC_core

<400>  11
gggtttggca tcgggcctgg c                                                 21


<210>  12
<211>  50
<212>  RNA
<213>  artificial sequence

<220>
<223>  aptamer ARACD3 3700006

<400>  12
uauagacuuu aaugucucau uuucgcagcg auucuuguuu auuuaacaua                  50


<210>  13
<211>  48
<212>  RNA
<213>  artificial sequence

<220>
<223>  aptamer ARACD3-0010209

<400>  13
ucuaagcaau auuguuugcu uuugcagcga uucuguuucg auauauua                    48


<210>  14
<211>  97
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  template for aptamer production


<220>
<221>  misc_feature
<222>  (24)..(43)
<223>  n is a, c, g, or t

<220>
<221>  misc_feature
<222>  (65)..(74)
<223>  n is a, c, g, or t

<400>  14
cctctctatg ggcagtcggt gatnnnnnnn nnnnnnnnnn nnntttctgc agcgattctt       60

gtttnnnnnn nnnnggagaa tgaggaaccc agtgcag                                97


<210>  15
<211>  43
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  primer

<400>  15
taatacgact cactataggg cctctctatg ggcagtcggt gat                         43


<210>  16
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  primer

<400>  16
ctgcactggg ttcctcattc tcc                                               23


<210>  17
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Blocking sequence

<400>  17
atcaccgact gcccatagag agg                                               23


<210>  18
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Blocking sequence

<400>  18
ctgcactggg ttcctcattc tcc                                               23


<210>  19
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Capture sequence


<220>
<221>  5'-cap
<222>  (1)..(1)
<223>  5' end capped with biotin-gtc-PEG6spacer

<400>  19
caagaatcgc tgcag                                                        15


