                         SEQUENCE LISTING

<110>  Yeda Research and Development Co. Ltd.
       SHARON, Michal
       OLSHINA, Maya
       DESHMUKH, Fanindra Kumar
       TAWFIK, Dan S.
 
<120>  INHIBITORS OF THE 20S PROTEASOME

<130>  76393

<150>  US 62/627,813
<151>  2018-02-08

<160>  19    

<170>  PatentIn version 3.5

<210>  1
<211>  10
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  1

Met Ala Ser Lys Arg Ala Leu Val Ile Leu 
1               5                   10  


<210>  2
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  2

Met Val Gly Arg Arg Ala Leu Ile Val 
1               5                   


<210>  3
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  3

Met Ala Gly Lys Lys Val Leu Ile Val 
1               5                   


<210>  4
<211>  10
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  4

Met Ser Ser Cys Ser Arg Val Ala Leu Val 
1               5                   10  


<210>  5
<211>  10
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  5

Met His Val Asn Gly Lys Val Ala Leu Val 
1               5                   10  


<210>  6
<211>  10
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  6

Met Ala Ser Pro Ser Lys Ala Val Ile Val 
1               5                   10  


<210>  7
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  7

Met Thr Glu Tyr Lys Leu Val Val Val 
1               5                   


<210>  8
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  8

Met Thr Glu Tyr Lys Leu Val Val Val 
1               5                   


<210>  9
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  9

Met Thr Glu Tyr Lys Leu Val Val Val 
1               5                   


<210>  10
<211>  11
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  10

Met Ala Ala Ile Arg Lys Lys Leu Val Ile Val 
1               5                   10      


<210>  11
<211>  11
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  11

Met Ala Ala Ile Arg Lys Lys Leu Val Val Val 
1               5                   10      


<210>  12
<211>  11
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  12

Met Ala Ala Ile Arg Lys Lys Leu Val Ile Val 
1               5                   10      


<210>  13
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  13

Met Arg Glu Tyr Lys Leu Val Val Leu 
1               5                   


<210>  14
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  14

Met Arg Glu Tyr Lys Leu Val Val Leu 
1               5                   


<210>  15
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  15

Met Arg Glu Tyr Lys Val Val Val Leu 
1               5                   


<210>  16
<211>  10
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  16

Met Ala Glu Leu Arg Val Leu Val Ala Val 
1               5                   10  


<210>  17
<211>  9
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome

<400>  17

Met Ala Ala Tyr Lys Leu Val Leu Ile 
1               5                   


<210>  18
<211>  6
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  X can be Arg or Lys

<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  X can be Arg or Lys or absent

<220>
<221>  MISC_FEATURE
<222>  (3)..(6)
<223>  X can be Val, Leu, Ile or Ala

<400>  18

Xaa Xaa Xaa Xaa Xaa Xaa 
1               5       


<210>  19
<211>  11
<212>  PRT
<213>  Artificial sequence

<220>
<223>  polypeptide  Sequence  capable of inhibiting the 20S proteasome


<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  Xaa can be any naturally occurring amino acid

<220>
<221>  MISC_FEATURE
<222>  (3)..(5)
<223>  Xaa can be any naturally occurring amino acid or absent

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  X can be Arg or Lys

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  X can be Arg or Lys or absent

<220>
<221>  MISC_FEATURE
<222>  (8)..(11)
<223>  X can be Val, Leu, Ile or Ala

<400>  19

Met Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 
1               5                   10      


