                         SEQUENCE LISTING

<110>  BicycleTx Limited
 
<120>  BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2

<130>  BIC-C-P2469PCT

<150>  GB1721259.8
<151>  2017-12-19

<150>  GB1804102.0
<151>  2018-03-14

<150>  GB1818603.1
<151>  2018-11-14

<160>  6     

<170>  PatentIn version 3.5

<210>  1
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Peptide


<220>
<221>  Xaa
<222>  (2)..(2)
<223>  X represents HyP

<220>
<221>  Xaa
<222>  (12)..(12)
<223>  Xaa represents D-Asp

<220>
<221>  Xaa
<222>  (14)..(14)
<223>  Xaa represents HArg

<400>  1

Cys Xaa Leu Val Asn Pro Leu Cys Leu His Pro Xaa Trp Xaa Cys 
1               5                   10                  15  


<210>  2
<211>  20
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Peptide


<220>
<221>  Xaa
<222>  (1)..(1)
<223>  Xaa represents Beta-Ala

<220>
<221>  Xaa
<222>  (2)..(2)
<223>  Xaa represents Sar10

<220>
<221>  Xaa
<222>  (4)..(4)
<223>  Xaa represents HArg

<220>
<221>  Xaa
<222>  (7)..(7)
<223>  Xaa represents HyP

<220>
<221>  Xaa
<222>  (17)..(17)
<223>  Xaa represents D-Asp

<220>
<221>  Xaa
<222>  (19)..(19)
<223>  Xaa represents HArg

<400>  2

Xaa Xaa Ala Xaa Asp Cys Xaa Leu Val Asn Pro Leu Cys Leu His Pro 
1               5                   10                  15      


Xaa Trp Xaa Cys 
            20  


<210>  3
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Linker


<220>
<221>  Xaa
<222>  (3)..(3)
<223>  Xaa represents Cit

<220>
<221>  Xaa
<222>  (5)..(5)
<223>  Xaa represents hPhe

<400>  3

Glu Pro Xaa Gly Xaa Tyr Leu 
1               5           


<210>  4
<211>  20
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Peptide


<220>
<221>  Xaa
<222>  (1)..(1)
<223>  Xaa represents Fl

<220>
<221>  Xaa
<222>  (3)..(3)
<223>  Xaa represents Sar5

<400>  4

Xaa Gly Xaa Ala Cys Pro Trp Gly Pro Ala Trp Cys Pro Val Asn Arg 
1               5                   10                  15      


Pro Gly Cys Ala 
            20  


<210>  5
<211>  20
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Peptide


<220>
<221>  Xaa
<222>  (1)..(1)
<223>  Xaa represents Fl

<220>
<221>  Xaa
<222>  (3)..(3)
<223>  Xaa represents Sar5

<400>  5

Xaa Gly Xaa Ala Cys Pro Trp Gly Pro Phe Trp Cys Pro Val Asn Arg 
1               5                   10                  15      


Pro Gly Cys Ala 
            20  


<210>  6
<211>  23
<212>  PRT
<213>  Artificial

<220>
<223>  Synthetic Peptide


<220>
<221>  Xaa
<222>  (1)..(1)
<223>  Xaa represents Fl

<220>
<221>  Xaa
<222>  (3)..(3)
<223>  Xaa represents Sar5

<400>  6

Xaa Gly Xaa Ala Asp Val Thr Cys Pro Trp Gly Pro Phe Trp Cys Pro 
1               5                   10                  15      


Val Asn Arg Pro Gly Cys Ala 
            20              


