                               SEQUENCE LISTING

<110> SOMALOGIC, INC.
 
<120> OLIGONUCLEOTIDES COMPRISING MODIFIED NUCLEOSIDES

<130> 01137-0020-00PCT

<140>
<141>

<150> 62/437,592
<151> 2016-12-21

<150> 62/357,623
<151> 2016-07-01

<160> 83    

<170> PatentIn version 3.5

<210> 1
<211> 79
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"


<220>
<221> modified_base
<222> (34)..(63)
<223> a, c, t, g, unknown or other

<400> 1
aatttttttt ctctttctct tctctctttc tccnnnnnnn nnnnnnnnnn nnnnnnnnnn       60

nnngacccac ccagcgtgg                                                    79


<210> 2
<211> 24
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 2
atatatatcc acgctgggtg ggtc                                              24


<210> 3
<211> 33
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 3
aatttttttt ctctttctct tctctctttc tcc                                    33


<210> 4
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 4
aagttccggc cgcctcgggg tccctgccaa                                        30


<210> 5
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 5
atacctggga ttccggccat ttgcgcagtt                                        30


<210> 6
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 6
tgaagttccg gccgtgcgca tggtacccat                                        30


<210> 7
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 7
tttgtgcttc cggcctagcg cagatatcct                                        30


<210> 8
<211> 29
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 8
ataggttccg gccttgcgct gtttagaca                                         29


<210> 9
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 9
tagatgcctg gtatttccgg ccttgcgcat                                        30


<210> 10
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 10
tagtgccctg atctattccg gccaagccca                                        30


<210> 11
<211> 31
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 11
tttgcccctg gttacgttcc ggcctggcgc a                                      31


<210> 12
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 12
atgccgttcc ggcctagcgc tcgttaccca                                        30


<210> 13
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 13
tgaccacctg tccaattccg gcctagcgca                                        30


<210> 14
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 14
taccaggtat tccggccgag cgctgctata                                        30


<210> 15
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 15
gagcccagtt acttccggcc ttgcattgta                                        30


<210> 16
<211> 29
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 16
aagagtttcc ggcctaccgc attcaccct                                         29


<210> 17
<211> 34
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 17
acagtcccac agtttaattc cggccgtagc cgct                                   34


<210> 18
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 18
ataccagggt cgttccggcc aagcgctgtt                                        30


<210> 19
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 19
gagttccggc ctagcgcaga agccctggat                                        30


<210> 20
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 20
ttttccagga attccggcca agcgctgtga                                        30


<210> 21
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 21
aattacctga ggattccggc caagcgcaga                                        30


<210> 22
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 22
ctgcgttacg ccttccggcc tggctgatag                                        30


<210> 23
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 23
tacctgagtt atgtattccg gccgtgcgca                                        30


<210> 24
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 24
caaagcattc cggccttgcg cagtagccct                                        30


<210> 25
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 25
gtagttccag attgattccg gccttgcgct                                        30


<210> 26
<211> 30
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 26
aatactccag gtgagttccg gccaagcgct                                        30


<210> 27
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 27
guuaucgcaa ugugcgcccg ggugcccgcc                                        30


<210> 28
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 28
ugugcccgga uauuaacugu uccgagcagu                                        30


<210> 29
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 29
uguuuaugca caugcccgcg augacaguaa                                        30


<210> 30
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 30
agugugauua ugcacuugcc cgcauuuggu                                        30


<210> 31
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 31
uauagaacau aaugcacaug cccgcauacu                                        30


<210> 32
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 32
uaucaguuua ugcacgugcc cgcgaugacu                                        30


<210> 33
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 33
gacuacgagg gaugaugcac augcccgcau                                        30


<210> 34
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 34
auaaugauua ugcacaugcc cgcaugucau                                        30


<210> 35
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 35
ggcaucgugu gcccgauuuu cuaaccggga                                        30


<210> 36
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 36
gccgaauuua ugcaccugcc cgcaugauuc                                        30


<210> 37
<211> 29
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 37
ccaaucauga cacaugcccg gaugauacu                                         29


<210> 38
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 38
uacgaugccc ggauauugac uguuccgucg                                        30


<210> 39
<211> 31
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 39
cguagcgacg ggcguggcau gcccggcccc c                                      31


<210> 40
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 40
uggugagagu gcccggauau uaacuguucc                                        30


<210> 41
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 41
ucaaaggccg ugugcccgau uuucuaaccg                                        30


<210> 42
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 42
uuucgaaguu gagcguggca auacuugccc                                        30


<210> 43
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 43
cguguuuaug cacuugcccg cgauuacacc                                        30


<210> 44
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 44
aacguacuuu aaggccuauu gaggaaacuc                                        30


<210> 45
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 45
cacuuuaaga ccuauugcgg agacccuggg                                        30


<210> 46
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 46
cgugcuuuaa gaccuguuga gaugcgcuca                                        30


<210> 47
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 47
acuuuaagac cuguugaggg ccucgggaau                                        30


<210> 48
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 48
gccgguguuu aagaacuguu ggggcacuuc                                        30


<210> 49
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 49
gcgcacuuua agaccuauug gggagaacuc                                        30


<210> 50
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 50
uuuaaggccu guugaggacc ucggcaugaa                                        30


<210> 51
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 51
caacuuuaag gccuguuggg agagcccuug                                        30


<210> 52
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 52
gaauaccacg cuuuaagacc uauuggaucg                                        30


<210> 53
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 53
gagaacuuua agaccuauug agggccucug                                        30


<210> 54
<211> 29
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 54
cgacuuuaag gccuauuggg ggacucgac                                         29


<210> 55
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 55
gaacacuuua agaccuguug ggaagcgucu                                        30


<210> 56
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 56
acuuuaaggc cuguugagga aaccgucuga                                        30


<210> 57
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 57
agcuuuaaga ccuguugaga auucgacaaa                                        30


<210> 58
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 58
agcuuuaaga ccuguugagc agccucgacc                                        30


<210> 59
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 59
gaaggucaag uggcacuuua aggccuguuc                                        30


<210> 60
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 60
aaaccacuuu aagaccuguu ggggcacucu                                        30


<210> 61
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 61
aaaccuuuaa gaccuauuga ggugggcuca                                        30


<210> 62
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 62
uaggcgcuuu aagaccuauu gagggacucc                                        30


<210> 63
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 63
gugacgcuuu aagaccuauu agggcacuuc                                        30


<210> 64
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 64
gaaaccacuu uaagaccuau ugagagacuc                                        30


<210> 65
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 65
gaaacuuuaa gaccuauuga gcaggaacuc                                        30


<210> 66

<400> 66
000


<210> 67
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 67
cgacuuuaag accuguugaa agucgcgggg                                        30


<210> 68
<211> 32
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 68
acuuuaagac cuguugagac cggcucggac au                                     32


<210> 69
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 69
gaacuuuaag accuguugag gaccaucacg                                        30


<210> 70
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 70
acguggaguc ggacacuuua aggccuguuc                                        30


<210> 71
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 71
ucgcgacuuu aaggccuauu gugggacucu                                        30


<210> 72
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 72
gcuuuaaggc cuauugagau cggcucgggu                                        30


<210> 73
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 73
gacuuuaagg ccuguugaag gucgagaguu                                        30


<210> 74
<211> 29
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 74
aacgaucuuu aaggccuguu aggggcuuc                                         29


<210> 75
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 75
caagcugccu cgcacuuuaa gacguguugg                                        30


<210> 76
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 76
accguguuua agaacuguug gggggaacuc                                        30


<210> 77
<211> 36
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 77
gaauaccacg cuuuaagacc uauugagaug cgcuca                                 36


<210> 78
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 78
uaagccugag aaaccacuuu aagaccuuuu                                        30


<210> 79
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 79
cgaacuuuaa gaccuguuga gcagcucuuc                                        30


<210> 80
<211> 30
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 80
agaaucuuua aggccugucg agaccucgag                                        30


<210> 81
<211> 15
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"


<220>
<221> misc_feature
<222> (1)..(1)
<223> /note="May or may not be present"

<220>
<221> misc_feature
<222> (15)..(15)
<223> /note="May or may not be present"

<220> 
<221> source
<223> /note="See specification as filed for detailed description of
      substitutions and preferred embodiments"

<400> 81
scccaagrmc crccv                                                        15


<210> 82
<211> 10
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 82
aatttttttt                                                              10


<210> 83
<211> 15
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 83
cuuuaaggcc uauug                                                        15
