                         SEQUENCE LISTING

<110>  Queen Mary University of London
 
<120>  Crystal structures

<130>  P63281WO/TCL

<140>  PCT/GB2017/050937
<141>  2017-06-01

<160>  42    

<170>  PatentIn version 3.5

<210>  1
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Bioactive epitope

<400>  1

Arg Gly Asp Ser 
1               


<210>  2
<211>  15
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  statherin-derived peptide

<400>  2

Asp Asp Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly 
1               5                   10                  15  


<210>  3
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (2)..(5)
<223>  X is any amino acid

<400>  3

Gly Xaa Xaa Xaa Xaa 
1               5   


<210>  4
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<400>  4

Xaa Gly Xaa Xaa Xaa 
1               5   


<210>  5
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<400>  5

Xaa Xaa Gly Xaa Xaa 
1               5   


<210>  6
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<400>  6

Xaa Xaa Xaa Gly Xaa 
1               5   


<210>  7
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<400>  7

Xaa Xaa Xaa Xaa Gly 
1               5   


<210>  8
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (2)..(5)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I.

<400>  8

Gly Xaa Xaa Xaa Xaa 
1               5   


<210>  9
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I.

<400>  9

Xaa Gly Xaa Xaa Xaa 
1               5   


<210>  10
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I.

<400>  10

Xaa Xaa Gly Xaa Xaa 
1               5   


<210>  11
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I.

<400>  11

Xaa Xaa Xaa Gly Xaa 
1               5   


<210>  12
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(4)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I.

<400>  12

Xaa Xaa Xaa Xaa Gly 
1               5   


<210>  13
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Pentapeptide is repeated any number of times

<220>
<221>  X
<222>  (2)..(5)
<223>  X is any amino acid

<400>  13

Gly Xaa Xaa Xaa Xaa 
1               5   


<210>  14
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Pentapeptide is repeated any number of times

<400>  14

Xaa Gly Xaa Xaa Xaa 
1               5   


<210>  15
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Pentapeptide is repeated any number of times

<400>  15

Xaa Xaa Gly Xaa Xaa 
1               5   


<210>  16
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(5)
<223>  X is any amino acid

<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Pentapeptide is repeated any number of times

<400>  16

Xaa Xaa Xaa Gly Xaa 
1               5   


<210>  17
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Pentapeptide


<220>
<221>  X
<222>  (1)..(4)
<223>  X is any amino acid

<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Pentapeptide is repeated any number of times

<400>  17

Xaa Xaa Xaa Xaa Gly 
1               5   


<210>  18
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  X
<222>  (4)..(4)
<223>  X is an amino acid selected from the group consisting of V, P, G,
       S, F and I

<400>  18

Val Pro Gly Xaa Gly 
1               5   


<210>  19
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  X
<222>  (4)..(4)
<223>  X is any amino acid apart from Proline

<400>  19

Val Pro Gly Xaa Gly 
1               5   


<210>  20
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Motif is to be repeated any number of times

<220>
<221>  X
<222>  (4)..(4)
<223>  X is any amino acid apart from Proline

<400>  20

Val Pro Gly Xaa Gly 
1               5   


<210>  21
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif

<400>  21

Pro Gly Ile Pro Gly 
1               5   


<210>  22
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Motif is to be repeated any number of times

<400>  22

Pro Gly Ile Pro Gly 
1               5   


<210>  23
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif

<400>  23

Pro Val Gly Ser Gly 
1               5   


<210>  24
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Motif is to be repeated any number of times

<400>  24

Pro Val Gly Ser Gly 
1               5   


<210>  25
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif

<400>  25

Val Gly Phe Pro Gly 
1               5   


<210>  26
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Tropoelastin recurrent motif


<220>
<221>  repeat_unit
<222>  (1)..(5)
<223>  Motif is to be repeated any number of times

<400>  26

Val Gly Phe Pro Gly 
1               5   


<210>  27
<211>  699
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  27

Met Gly Ser Ser His His His His His His Ser Ser Gly Leu Val Pro 
1               5                   10                  15      


Arg Gly Ser His Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    50                  55                  60                  


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
65                  70                  75                  80  


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
                85                  90                  95      


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
            100                 105                 110         


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
        115                 120                 125             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
    130                 135                 140                 


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
145                 150                 155                 160 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
                165                 170                 175     


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
            180                 185                 190         


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
        195                 200                 205             


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
    210                 215                 220                 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
225                 230                 235                 240 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
                245                 250                 255     


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
            260                 265                 270         


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
        275                 280                 285             


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
    290                 295                 300                 


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
305                 310                 315                 320 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
                325                 330                 335     


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
            340                 345                 350         


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
        355                 360                 365             


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
    370                 375                 380                 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
385                 390                 395                 400 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
                405                 410                 415     


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
            420                 425                 430         


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
        435                 440                 445             


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
    450                 455                 460                 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
465                 470                 475                 480 


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
                485                 490                 495     


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
            500                 505                 510         


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
        515                 520                 525             


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
    530                 535                 540                 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
545                 550                 555                 560 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                565                 570                 575     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            580                 585                 590         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        595                 600                 605             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    610                 615                 620                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
625                 630                 635                 640 


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
                645                 650                 655     


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
            660                 665                 670         


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
        675                 680                 685             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
    690                 695                 


<210>  28
<211>  877
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  28

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Glu 
            20                  25                  30          


Glu Ile Gln Ile Gly His Ile Pro Arg Glu Asp Val Asp Tyr His Leu 
        35                  40                  45              


Tyr Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
    50                  55                  60                  


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Gly Val Ala Pro 
65                  70                  75                  80  


Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Pro Gly 
                85                  90                  95      


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
            100                 105                 110         


Gly Val Pro Gly Ile Gly Glu Glu Ile Gln Ile Gly His Ile Pro Arg 
        115                 120                 125             


Glu Asp Val Asp Tyr His Leu Tyr Pro Val Pro Gly Ile Gly Val Pro 
    130                 135                 140                 


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
145                 150                 155                 160 


Ile Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Gly 
                165                 170                 175     


Val Ala Pro Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
            180                 185                 190         


Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Glu Glu Ile 
        195                 200                 205             


Gln Ile Gly His Ile Pro Arg Glu Asp Val Asp Tyr His Leu Tyr Pro 
    210                 215                 220                 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
225                 230                 235                 240 


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Gly Val Ala Pro Gly Val 
                245                 250                 255     


Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Pro Gly Ile Gly 
            260                 265                 270         


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
        275                 280                 285             


Pro Gly Ile Gly Glu Glu Ile Gln Ile Gly His Ile Pro Arg Glu Asp 
    290                 295                 300                 


Val Asp Tyr His Leu Tyr Pro Val Pro Gly Ile Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Gly Val Ala 
            340                 345                 350         


Pro Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
        355                 360                 365             


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Glu Glu Ile Gln Ile 
    370                 375                 380                 


Gly His Ile Pro Arg Glu Asp Val Asp Tyr His Leu Tyr Pro Val Pro 
385                 390                 395                 400 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly 
                405                 410                 415     


Ile Gly Val Pro Gly Ile Gly Val Gly Val Ala Pro Gly Val Gly Val 
            420                 425                 430         


Ala Pro Gly Val Gly Val Ala Pro Gly Val Pro Gly Ile Gly Val Pro 
        435                 440                 445             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    450                 455                 460                 


Ile Gly Glu Glu Ile Gln Ile Gly His Ile Pro Arg Glu Asp Val Asp 
465                 470                 475                 480 


Tyr His Leu Tyr Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
                485                 490                 495     


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Gly 
            500                 505                 510         


Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly 
        515                 520                 525             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
    530                 535                 540                 


Pro Gly Ile Gly Val Pro Gly Ile Gly Glu Glu Ile Gln Ile Gly His 
545                 550                 555                 560 


Ile Pro Arg Glu Asp Val Asp Tyr His Leu Tyr Pro Val Pro Gly Ile 
                565                 570                 575     


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
            580                 585                 590         


Val Pro Gly Ile Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro 
        595                 600                 605             


Gly Val Gly Val Ala Pro Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
    610                 615                 620                 


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
625                 630                 635                 640 


Glu Glu Ile Gln Ile Gly His Ile Pro Arg Glu Asp Val Asp Tyr His 
                645                 650                 655     


Leu Tyr Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
            660                 665                 670         


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Gly Val Ala 
        675                 680                 685             


Pro Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val Pro 
    690                 695                 700                 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly 
705                 710                 715                 720 


Ile Gly Val Pro Gly Ile Gly Glu Glu Ile Gln Ile Gly His Ile Pro 
                725                 730                 735     


Arg Glu Asp Val Asp Tyr His Leu Tyr Pro Val Pro Gly Ile Gly Val 
            740                 745                 750         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        755                 760                 765             


Gly Ile Gly Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val 
    770                 775                 780                 


Gly Val Ala Pro Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
785                 790                 795                 800 


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Glu Glu 
                805                 810                 815     


Ile Gln Ile Gly His Ile Pro Arg Glu Asp Val Asp Tyr His Leu Tyr 
            820                 825                 830         


Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
        835                 840                 845             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Gly Val Ala Pro Gly 
    850                 855                 860                 


Val Gly Val Ala Pro Gly Val Gly Val Ala Pro Gly Val 
865                 870                 875         


<210>  29
<211>  1107
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  29

Met Glu Ser Leu Leu Pro Val Pro Gly Val Gly Val Pro Gly Val Gly 
1               5                   10                  15      


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            20                  25                  30          


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        35                  40                  45              


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    50                  55                  60                  


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
65                  70                  75                  80  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                85                  90                  95      


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            100                 105                 110         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        115                 120                 125             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    130                 135                 140                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
145                 150                 155                 160 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                165                 170                 175     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            180                 185                 190         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        195                 200                 205             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    210                 215                 220                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
225                 230                 235                 240 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                245                 250                 255     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            260                 265                 270         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        275                 280                 285             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    290                 295                 300                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro 
305                 310                 315                 320 


Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                325                 330                 335     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            340                 345                 350         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        355                 360                 365             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    370                 375                 380                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro 
385                 390                 395                 400 


Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                405                 410                 415     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            420                 425                 430         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        435                 440                 445             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    450                 455                 460                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro 
465                 470                 475                 480 


Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                485                 490                 495     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            500                 505                 510         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        515                 520                 525             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    530                 535                 540                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Pro Gly Val 
545                 550                 555                 560 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                565                 570                 575     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            580                 585                 590         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        595                 600                 605             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    610                 615                 620                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
625                 630                 635                 640 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                645                 650                 655     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val 
            660                 665                 670         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        675                 680                 685             


Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly 
    690                 695                 700                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu 
705                 710                 715                 720 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                725                 730                 735     


Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val 
            740                 745                 750         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        755                 760                 765             


Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    770                 775                 780                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val 
785                 790                 795                 800 


Gly Val Pro Gly Val Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                805                 810                 815     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            820                 825                 830         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        835                 840                 845             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    850                 855                 860                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro 
865                 870                 875                 880 


Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                885                 890                 895     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            900                 905                 910         


Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly 
        915                 920                 925             


Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile 
    930                 935                 940                 


Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro 
945                 950                 955                 960 


Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly 
                965                 970                 975     


Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val Gly Ile Pro Gly Val 
            980                 985                 990         


Gly Ile Pro Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
        995                 1000                 1005             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1010                 1015                 1020             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1025                 1030                 1035             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1040                 1045                 1050             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1055                 1060                 1065             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1070                 1075                 1080             


Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly Ile Pro  Gly Val Gly 
    1085                 1090                 1095             


Ile Pro  Gly Val Gly Ile Pro  Gly Val 
    1100                 1105         


<210>  30
<211>  607
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  30

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    50                  55                  60                  


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                165                 170                 175     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly 
    210                 215                 220                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            260                 265                 270         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        275                 280                 285             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        355                 360                 365             


Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    370                 375                 380                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
385                 390                 395                 400 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                405                 410                 415     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            420                 425                 430         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        435                 440                 445             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    450                 455                 460                 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
465                 470                 475                 480 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                485                 490                 495     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            500                 505                 510         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        515                 520                 525             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    530                 535                 540                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
545                 550                 555                 560 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                565                 570                 575     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            580                 585                 590         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
        595                 600                 605         


<210>  31
<211>  376
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Protein sequence

<400>  31

Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val 
1               5                   10                  15      


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
            20                  25                  30          


Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly 
        35                  40                  45              


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu 
    50                  55                  60                  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
65                  70                  75                  80  


Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val 
                85                  90                  95      


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
            100                 105                 110         


Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
        115                 120                 125             


Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val 
    130                 135                 140                 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
145                 150                 155                 160 


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
                165                 170                 175     


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
            180                 185                 190         


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
        195                 200                 205             


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
    210                 215                 220                 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
225                 230                 235                 240 


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
                245                 250                 255     


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
            260                 265                 270         


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
        275                 280                 285             


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
    290                 295                 300                 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
305                 310                 315                 320 


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
                325                 330                 335     


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
            340                 345                 350         


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
        355                 360                 365             


Val Gly Val Pro Gly Val Gly Val 
    370                 375     


<210>  32
<211>  352
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  32

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    50                  55                  60                  


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                165                 170                 175     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    210                 215                 220                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            260                 265                 270         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp 
        275                 280                 285             


Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


<210>  33
<211>  452
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  33

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    50                  55                  60                  


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                165                 170                 175     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    210                 215                 220                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            260                 265                 270         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp 
        275                 280                 285             


Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        355                 360                 365             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    370                 375                 380                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
385                 390                 395                 400 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                405                 410                 415     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            420                 425                 430         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        435                 440                 445             


Ala Val Gly Val 
    450         


<210>  34
<211>  797
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  34

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    50                  55                  60                  


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                165                 170                 175     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    210                 215                 220                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            260                 265                 270         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp 
        275                 280                 285             


Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        355                 360                 365             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    370                 375                 380                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
385                 390                 395                 400 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                405                 410                 415     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            420                 425                 430         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        435                 440                 445             


Ala Val Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    450                 455                 460                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
465                 470                 475                 480 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                485                 490                 495     


Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu Arg Arg Ile 
            500                 505                 510         


Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        515                 520                 525             


Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    530                 535                 540                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
545                 550                 555                 560 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                565                 570                 575     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            580                 585                 590         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        595                 600                 605             


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    610                 615                 620                 


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
625                 630                 635                 640 


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                645                 650                 655     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            660                 665                 670         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        675                 680                 685             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    690                 695                 700                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
705                 710                 715                 720 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                725                 730                 735     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            740                 745                 750         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        755                 760                 765             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    770                 775                 780                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
785                 790                 795         


<210>  35
<211>  457
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  35

Met Glu Ser Leu Leu Pro Val Pro Gly Val Gly Val Pro Gly Val Gly 
1               5                   10                  15      


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            20                  25                  30          


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        35                  40                  45              


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    50                  55                  60                  


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
65                  70                  75                  80  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                85                  90                  95      


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            100                 105                 110         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        115                 120                 125             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    130                 135                 140                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
145                 150                 155                 160 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                165                 170                 175     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            180                 185                 190         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        195                 200                 205             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    210                 215                 220                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
225                 230                 235                 240 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                245                 250                 255     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            260                 265                 270         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        275                 280                 285             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    290                 295                 300                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
305                 310                 315                 320 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                325                 330                 335     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            340                 345                 350         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        355                 360                 365             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    370                 375                 380                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
385                 390                 395                 400 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                405                 410                 415     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            420                 425                 430         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        435                 440                 445             


Ala Val Gly Val Pro Ala Val Gly Val 
    450                 455         


<210>  36
<211>  557
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  36

Met Glu Ser Leu Leu Pro Val Pro Gly Val Gly Val Pro Gly Val Gly 
1               5                   10                  15      


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            20                  25                  30          


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        35                  40                  45              


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    50                  55                  60                  


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
65                  70                  75                  80  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                85                  90                  95      


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            100                 105                 110         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        115                 120                 125             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    130                 135                 140                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
145                 150                 155                 160 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                165                 170                 175     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            180                 185                 190         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        195                 200                 205             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    210                 215                 220                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
225                 230                 235                 240 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                245                 250                 255     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            260                 265                 270         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        275                 280                 285             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    290                 295                 300                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
305                 310                 315                 320 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                325                 330                 335     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            340                 345                 350         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        355                 360                 365             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    370                 375                 380                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
385                 390                 395                 400 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                405                 410                 415     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            420                 425                 430         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        435                 440                 445             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    450                 455                 460                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
465                 470                 475                 480 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                485                 490                 495     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            500                 505                 510         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        515                 520                 525             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    530                 535                 540                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
545                 550                 555         


<210>  37
<211>  707
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  37

Met Glu Ser Leu Leu Pro Val Pro Gly Val Gly Val Pro Gly Val Gly 
1               5                   10                  15      


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            20                  25                  30          


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        35                  40                  45              


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    50                  55                  60                  


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
65                  70                  75                  80  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                85                  90                  95      


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            100                 105                 110         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        115                 120                 125             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    130                 135                 140                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
145                 150                 155                 160 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                165                 170                 175     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            180                 185                 190         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        195                 200                 205             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    210                 215                 220                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
225                 230                 235                 240 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                245                 250                 255     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val 
            260                 265                 270         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        275                 280                 285             


Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly 
    290                 295                 300                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu 
305                 310                 315                 320 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                325                 330                 335     


Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val 
            340                 345                 350         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        355                 360                 365             


Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    370                 375                 380                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val 
385                 390                 395                 400 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                405                 410                 415     


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            420                 425                 430         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        435                 440                 445             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    450                 455                 460                 


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
465                 470                 475                 480 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                485                 490                 495     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Ala Val Gly Val 
            500                 505                 510         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        515                 520                 525             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    530                 535                 540                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
545                 550                 555                 560 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                565                 570                 575     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            580                 585                 590         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        595                 600                 605             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    610                 615                 620                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
625                 630                 635                 640 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                645                 650                 655     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            660                 665                 670         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        675                 680                 685             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    690                 695                 700                 


Val Gly Val 
705         


<210>  38
<211>  707
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide sequence

<400>  38

Met Glu Ser Leu Leu Pro Val Pro Gly Val Gly Val Pro Gly Val Gly 
1               5                   10                  15      


Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            20                  25                  30          


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro 
        35                  40                  45              


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    50                  55                  60                  


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
65                  70                  75                  80  


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                85                  90                  95      


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            100                 105                 110         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        115                 120                 125             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    130                 135                 140                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
145                 150                 155                 160 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                165                 170                 175     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            180                 185                 190         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        195                 200                 205             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    210                 215                 220                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
225                 230                 235                 240 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                245                 250                 255     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            260                 265                 270         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        275                 280                 285             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    290                 295                 300                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
305                 310                 315                 320 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                325                 330                 335     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            340                 345                 350         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        355                 360                 365             


Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala 
    370                 375                 380                 


Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val 
385                 390                 395                 400 


Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly 
                405                 410                 415     


Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val 
            420                 425                 430         


Pro Ala Val Gly Val Pro Ala Val Gly Val Pro Ala Val Gly Val Pro 
        435                 440                 445             


Ala Val Gly Val Pro Ala Val Gly Val Pro Gly Val Gly Val Pro Gly 
    450                 455                 460                 


Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val 
465                 470                 475                 480 


Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly 
                485                 490                 495     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            500                 505                 510         


Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro 
        515                 520                 525             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly 
    530                 535                 540                 


Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
545                 550                 555                 560 


Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly 
                565                 570                 575     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val 
            580                 585                 590         


Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        595                 600                 605             


Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly 
    610                 615                 620                 


Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val 
625                 630                 635                 640 


Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly Val Gly 
                645                 650                 655     


Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Glu Gly Val 
            660                 665                 670         


Pro Gly Val Gly Val Pro Gly Val Gly Val Pro Gly Val Gly Val Pro 
        675                 680                 685             


Gly Val Gly Val Pro Gly Glu Gly Val Pro Gly Val Gly Val Pro Gly 
    690                 695                 700                 


Val Gly Val 
705         


<210>  39
<211>  698
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Bioactive sequence

<400>  39

Met Gly Ser Ser His His His His His His Ser Ser Gly Leu Val Pro 
1               5                   10                  15      


Arg Gly Ser His Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    50                  55                  60                  


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
65                  70                  75                  80  


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
                85                  90                  95      


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
            100                 105                 110         


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
        115                 120                 125             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
    130                 135                 140                 


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
145                 150                 155                 160 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
                165                 170                 175     


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
            180                 185                 190         


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
        195                 200                 205             


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
    210                 215                 220                 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
225                 230                 235                 240 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
                245                 250                 255     


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
            260                 265                 270         


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
        275                 280                 285             


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
    290                 295                 300                 


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
305                 310                 315                 320 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
                325                 330                 335     


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
            340                 345                 350         


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
        355                 360                 365             


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
    370                 375                 380                 


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
385                 390                 395                 400 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
                405                 410                 415     


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
            420                 425                 430         


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
        435                 440                 445             


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
    450                 455                 460                 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
465                 470                 475                 480 


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
                485                 490                 495     


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
            500                 505                 510         


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
        515                 520                 525             


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
    530                 535                 540                 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
545                 550                 555                 560 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                565                 570                 575     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            580                 585                 590         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        595                 600                 605             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    610                 615                 620                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Ala Val Thr Gly 
625                 630                 635                 640 


Arg Gly Asp Ser Pro Ala Ser Ser Val Pro Gly Ile Gly Val Pro Gly 
                645                 650                 655     


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
            660                 665                 670         


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
        675                 680                 685             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
    690                 695             


<210>  40
<211>  606
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  ELP membrane sequence

<400>  40

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    50                  55                  60                  


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                165                 170                 175     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly 
    210                 215                 220                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            260                 265                 270         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        275                 280                 285             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        355                 360                 365             


Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    370                 375                 380                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
385                 390                 395                 400 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                405                 410                 415     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            420                 425                 430         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        435                 440                 445             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    450                 455                 460                 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
465                 470                 475                 480 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly 
                485                 490                 495     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            500                 505                 510         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        515                 520                 525             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    530                 535                 540                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
545                 550                 555                 560 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                565                 570                 575     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            580                 585                 590         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
        595                 600                 605     


<210>  41
<211>  351
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  ELP membrane sequence

<400>  41

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    50                  55                  60                  


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                165                 170                 175     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    210                 215                 220                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            260                 265                 270         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp 
        275                 280                 285             


Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
            340                 345                 350     


<210>  42
<211>  914
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  ELP membrane sequence

<400>  42

Met Glu Ser Leu Leu Pro Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
1               5                   10                  15      


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            20                  25                  30          


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        35                  40                  45              


Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu Lys Phe Leu 
    50                  55                  60                  


Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
65                  70                  75                  80  


Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                85                  90                  95      


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            100                 105                 110         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        115                 120                 125             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    130                 135                 140                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
145                 150                 155                 160 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp Asp Glu Glu 
                165                 170                 175     


Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly Ile Gly Val 
            180                 185                 190         


Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro 
        195                 200                 205             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    210                 215                 220                 


Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
225                 230                 235                 240 


Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly 
                245                 250                 255     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            260                 265                 270         


Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Asp Asp 
        275                 280                 285             


Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly Val Pro Gly 
    290                 295                 300                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile 
305                 310                 315                 320 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                325                 330                 335     


Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val 
            340                 345                 350         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro 
        355                 360                 365             


Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly 
    370                 375                 380                 


Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly Ile 
385                 390                 395                 400 


Gly Asp Asp Asp Glu Glu Lys Phe Leu Arg Arg Ile Gly Arg Phe Gly 
                405                 410                 415     


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
            420                 425                 430         


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
        435                 440                 445             


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
    450                 455                 460                 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
465                 470                 475                 480 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
                485                 490                 495     


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
            500                 505                 510         


Pro Gly Ile Gly Ala Val Thr Gly Arg Gly Asp Ser Pro Ala Ser Ser 
        515                 520                 525             


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
    530                 535                 540                 


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
545                 550                 555                 560 


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
                565                 570                 575     


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
            580                 585                 590         


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
        595                 600                 605             


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
    610                 615                 620                 


Pro Gly Ile Gly Ala Val Thr Gly Arg Gly Asp Ser Pro Ala Ser Ser 
625                 630                 635                 640 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
                645                 650                 655     


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
            660                 665                 670         


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
        675                 680                 685             


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
    690                 695                 700                 


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
705                 710                 715                 720 


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
                725                 730                 735     


Pro Gly Ile Gly Ala Val Thr Gly Arg Gly Asp Ser Pro Ala Ser Ser 
            740                 745                 750         


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
        755                 760                 765             


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
    770                 775                 780                 


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
785                 790                 795                 800 


Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys 
                805                 810                 815     


Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly 
            820                 825                 830         


Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val 
        835                 840                 845             


Pro Gly Ile Gly Ala Val Thr Gly Arg Gly Asp Ser Pro Ala Ser Ser 
    850                 855                 860                 


Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Lys Gly Val 
865                 870                 875                 880 


Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro Gly Ile Gly Val Pro 
                885                 890                 895     


Gly Ile Gly Val Pro Gly Lys Gly Val Pro Gly Ile Gly Val Pro Gly 
            900                 905                 910         


Ile Gly 
        


