                         SEQUENCE LISTING

<110>  Onxeo et al
 
<120>  TREATMENT OF CANCER BY SYSTEMIC ADMINISTRATION OF DBAIT MOLECULES

<130>  B2196PC

<160>  11    

<170>  PatentIn version 3.5

<210>  1
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  Dbait32

<400>  1
acgcacgggt gttgggtcgt ttgttcggat ct                                     32


<210>  2
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  Dbait32Ha

<400>  2
cgtaggtctg tttggtggct ttgcagtggc ac                                     32


<210>  3
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  Dbait32Hb

<400>  3
gctaggcttg tttgctgggt tgtaggcaca gc                                     32


<210>  4
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  Dbait32Hc

<400>  4
gctgtgccca caacccagca aacaagccta ga                                     32


<210>  5
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  Dbait32Hd

<400>  5
gctaggtctg tttggtggct ttgcagtggc ac                                     32


<210>  6
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule Ia


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 
       nucleotides with phosphorothioate or methylphosphonate backbone"

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate or methylphosphonate backbone

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, Lm = carboxamido oligoethylene glycol + C = single
       or double chain fatty acids, cholesterol, sugars, peptides or 
       proteins

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =hexaethyleneglycol, tetradeoxythymidylate or 
       1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane

<400>  6
acgcacgggt gttgggtcgt ttgttcggat ct                                     32


<210>  7
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule Ib


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 

       nucleotides with phosphorothioate or methylphosphonate backbone"

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate or methylphosphonate backbone

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, Lm = carboxamido oligoethylene glycol + C = 
       single

       or double chain fatty acids, cholesterol, sugars, peptides or 

       proteins

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =hexaethyleneglycol, tetradeoxythymidylate or 

       1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane

<400>  7
cgtaggtctg tttggtggct ttgcagtggc ac                                     32


<210>  8
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule Ic


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 
       nucleotides with phosphorothioate or methylphosphonate backbone"

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate or methylphosphonate backbone

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, Lm = carboxamido oligoethylene glycol + C = single
       or double chain fatty acids, cholesterol, sugars, peptides or 
       proteins

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =hexaethyleneglycol, tetradeoxythymidylate or 
       1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane

<400>  8
gctaggcttg tttgctgggt tgtaggcaca gc                                     32


<210>  9
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule Id


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 
       nucleotides with phosphorothioate or methylphosphonate backbone"

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate or methylphosphonate backbone

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, Lm = carboxamido oligoethylene glycol + C = single
       or double chain fatty acids, cholesterol, sugars, peptides or 
       proteins

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =hexaethyleneglycol, tetradeoxythymidylate or 
       1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane

<400>  9
gctgtgccca caacccagca aacaagccta ga                                     32


<210>  10
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule Ie


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 
       nucleotides with phosphorothioate or methylphosphonate backbone"

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, Lm = carboxamido oligoethylene glycol + C = single
       or double chain fatty acids, cholesterol, sugars, peptides or 
       proteins

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate or methylphosphonate backbone

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =hexaethyleneglycol, tetradeoxythymidylate or 
       1,19-bis(phospho)-8-hydraza-2-hydroxy-4-oxa-9-oxo-nonadecane

<400>  10
gctaggtctg tttggtggct ttgcagtggc ac                                     32


<210>  11
<211>  32
<212>  DNA
<213>  artificial sequence

<220>
<223>  nucleic acid molecule DT01


<220>
<221>  misc_feature
<223>  note="at the 3' end of the complementary strand the three last 
       nucleotides with phosphorothioate backbone"

<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  at the 5' end, 
       10-O-[1-propyl-3-N-carbamoylcholesteryl]-tetraethyleneglycol 
       radical

<220>
<221>  modified_base
<222>  (1)..(3)
<223>  mod_base= phosphorothioate  backbone

<220>
<221>  stem_loop
<222>  (1)..(32)

<220>
<221>  misc_feature
<222>  (32)..(32)
<223>  loop L' =  
       2,19-bis(phosphor)-8-hydraza-1-hydroxy-4-oxa-9-oxo-nonadecane

<400>  11
gctgtgccca caacccagca aacaagccta ga                                     32


