                         SEQUENCE LISTING

<110>  THE UNIVERSITY OF BRITISH COLUMBIA
 
<120>  C-terminal epitopes in Amyloid beta and 
       conformationally-selective antibodies thereto

<130>  7685-P50439PC00

<150>  62/253,044
<151>  2015-11-09

<150>  62/352,346
<151>  2016-06-20

<150>  62/365,634
<151>  2016-07-22

<150>  62/393,615
<151>  2016-09-12

<160>  26    

<170>  PatentIn version 3.5

<210>  1
<211>  4
<212>  PRT
<213>  Homo sapiens

<400>  1

Gly Gly Val Val 
1               


<210>  2
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  2

Cys Gly Gly Gly Val Val Gly 
1               5           


<210>  3
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  3

Cys Gly Gly Val Val Gly 
1               5       


<210>  4
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  4

Cys Gly Gly Gly Val Val 
1               5       


<210>  5
<211>  4
<212>  PRT
<213>  Homo sapiens

<400>  5

Val Gly Gly Val 
1               


<210>  6
<211>  5
<212>  PRT
<213>  Homo sapiens

<400>  6

Val Gly Gly Val Val 
1               5   


<210>  7
<211>  6
<212>  PRT
<213>  Homo sapiens

<400>  7

Val Gly Gly Val Val Ile 
1               5       


<210>  8
<211>  5
<212>  PRT
<213>  Homo sapiens

<400>  8

Gly Gly Val Val Ile 
1               5   


<210>  9
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  9

Gly Gly Gly Val Val Gly 
1               5       


<210>  10
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  10

Gly Gly Val Val Gly 
1               5   


<210>  11
<211>  5
<212>  PRT
<213>  Homo sapiens

<400>  11

Gly Gly Gly Val Val 
1               5   


<210>  12
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic Construct

<400>  12

Cys Gly Gly Gly Val Val Gly Cys 
1               5               


<210>  13
<211>  11
<212>  PRT
<213>  Homo sapiens

<400>  13

Ala Ile Ile Gly Leu Met Val Gly Gly Val Val 
1               5                   10      


<210>  14
<211>  6
<212>  PRT
<213>  Homo sapiens

<400>  14

Met Val Gly Gly Val Val 
1               5       


<210>  15
<211>  6
<212>  PRT
<213>  Homo sapiens

<400>  15

Gly Gly Val Val Ile Ala 
1               5       


<210>  16
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  16

Asp Ala Glu Phe Arg His Asp Ser Gly Tyr Glu Val His His Gln Lys 
1               5                   10                  15      


Leu Val Phe Phe Ala Glu Asp Val Gly Ser Asn Lys Gly Ala Ile Ile 
            20                  25                  30          


Gly Leu Met Val Gly Gly Val Val Ile Ala 
        35                  40          


<210>  17
<211>  8
<212>  PRT
<213>  Mus musculus

<400>  17

Gly Phe Thr Phe Ser Asn Tyr Trp 
1               5               


<210>  18
<211>  10
<212>  PRT
<213>  Mus musculus

<400>  18

Ile Arg Leu Lys Ser Tyr Asn Tyr Ala Thr 
1               5                   10  


<210>  19
<211>  6
<212>  PRT
<213>  Mus musculus

<400>  19

Leu Arg Trp Ile Asp Tyr 
1               5       


<210>  20
<211>  6
<212>  PRT
<213>  Mus musculus

<400>  20

Gln Asp Ile Asn Ser Tyr 
1               5       


<210>  21
<211>  3
<212>  PRT
<213>  Mus musculus

<400>  21

Arg Ala Asn 
1           


<210>  22
<211>  9
<212>  PRT
<213>  Mus musculus

<400>  22

Pro Gln Tyr Asp Glu Phe Pro Tyr Thr 
1               5                   


<210>  23
<211>  414
<212>  DNA
<213>  Mus musculus

<400>  23
atgtatttgg gactgaactg tgtattcata gtttttctct taaaaggtgt ccagagtgaa       60

gtgaagcttg aggagtctgg aggaggcttg gtgcaacctg gaggatccat gaaactctcc      120

tgtgttgcct ctggattcac tttcagtaac tactggatga actgggtccg ccagtctcca      180

gagaaggggc ttgagtgggt tgctgaaatt agattgaaat cttataatta tgcaacacat      240

tatgcggagt ctgtgaaagg gaggttcacc atctcaagag atgattccaa aagtagtgtc      300

tacctgcaaa tgaacaactt aagagctgaa gacactggca tttattactg tttacggtgg      360

atcgactact ggggccaagg caccactctc acagtctcct cagccaaaac gaca            414


<210>  24
<211>  138
<212>  PRT
<213>  Mus musculus

<400>  24

Met Tyr Leu Gly Leu Asn Cys Val Phe Ile Val Phe Leu Leu Lys Gly 
1               5                   10                  15      


Val Gln Ser Glu Val Lys Leu Glu Glu Ser Gly Gly Gly Leu Val Gln 
            20                  25                  30          


Pro Gly Gly Ser Met Lys Leu Ser Cys Val Ala Ser Gly Phe Thr Phe 
        35                  40                  45              


Ser Asn Tyr Trp Met Asn Trp Val Arg Gln Ser Pro Glu Lys Gly Leu 
    50                  55                  60                  


Glu Trp Val Ala Glu Ile Arg Leu Lys Ser Tyr Asn Tyr Ala Thr His 
65                  70                  75                  80  


Tyr Ala Glu Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asp Ser 
                85                  90                  95      


Lys Ser Ser Val Tyr Leu Gln Met Asn Asn Leu Arg Ala Glu Asp Thr 
            100                 105                 110         


Gly Ile Tyr Tyr Cys Leu Arg Trp Ile Asp Tyr Trp Gly Gln Gly Thr 
        115                 120                 125             


Thr Leu Thr Val Ser Ser Ala Lys Thr Thr 
    130                 135             


<210>  25
<211>  399
<212>  DNA
<213>  Mus musculus

<400>  25
atggacatga ggacccctgc tcagtttctt ggaatcttgt tgctctggtt tccaggtatc       60

aaatgtgaca tcaagatgac ccagtctcca tcttccatgt atgcatctct aggagagaga      120

gtcactatca cttgcaaggc gagtcaggac attaatagct atttaagctg gttccagcag      180

aaaccaggga aatctcctaa gaccctgatc tatcgtgcaa acagattggt agatggggtc      240

ccatcaaggt tcagtggcag tggatctggg caagattatt ctctcaccat cagcagcctg      300

gagtatgaag atatgggaat ttattattgt ccacagtatg atgagtttcc gtacacgttc      360

ggagggggga ccaagctgga aataaaacgg gctgatgct                             399


<210>  26
<211>  133
<212>  PRT
<213>  Mus musculus

<400>  26

Met Asp Met Arg Thr Pro Ala Gln Phe Leu Gly Ile Leu Leu Leu Trp 
1               5                   10                  15      


Phe Pro Gly Ile Lys Cys Asp Ile Lys Met Thr Gln Ser Pro Ser Ser 
            20                  25                  30          


Met Tyr Ala Ser Leu Gly Glu Arg Val Thr Ile Thr Cys Lys Ala Ser 
        35                  40                  45              


Gln Asp Ile Asn Ser Tyr Leu Ser Trp Phe Gln Gln Lys Pro Gly Lys 
    50                  55                  60                  


Ser Pro Lys Thr Leu Ile Tyr Arg Ala Asn Arg Leu Val Asp Gly Val 
65                  70                  75                  80  


Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Gln Asp Tyr Ser Leu Thr 
                85                  90                  95      


Ile Ser Ser Leu Glu Tyr Glu Asp Met Gly Ile Tyr Tyr Cys Pro Gln 
            100                 105                 110         


Tyr Asp Glu Phe Pro Tyr Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile 
        115                 120                 125             


Lys Arg Ala Asp Ala 
    130             


