                         SEQUENCE LISTING

<110>  Mumm, John B.
       Chan, Ivan H.
 
<120>  METHODS OF USING INTERLEUKIN-10 FOR TREATING DISEASES AND 
       DISORDERS

<130>  ARMO-019WO

<150>  US 62/209,500
<151>  2015-08-25

<160>  28    

<170>  PatentIn version 3.5

<210>  1
<211>  162
<212>  PRT
<213>  Homo sapiens

<400>  1

Met Arg Ile Ser Lys Pro His Leu Arg Ser Ile Ser Ile Gln Cys Tyr 
1               5                   10                  15      


Leu Cys Leu Leu Leu Asn Ser His Phe Leu Thr Glu Ala Gly Ile His 
            20                  25                  30          


Val Phe Ile Leu Gly Cys Phe Ser Ala Gly Leu Pro Lys Thr Glu Ala 
        35                  40                  45              


Asn Trp Val Asn Val Ile Ser Asp Leu Lys Lys Ile Glu Asp Leu Ile 
    50                  55                  60                  


Gln Ser Met His Ile Asp Ala Thr Leu Tyr Thr Glu Ser Asp Val His 
65                  70                  75                  80  


Pro Ser Cys Lys Val Thr Ala Met Lys Cys Phe Leu Leu Glu Leu Gln 
                85                  90                  95      


Val Ile Ser Leu Glu Ser Gly Asp Ala Ser Ile His Asp Thr Val Glu 
            100                 105                 110         


Asn Leu Ile Ile Leu Ala Asn Asn Ser Leu Ser Ser Asn Gly Asn Val 
        115                 120                 125             


Thr Glu Ser Gly Cys Lys Glu Cys Glu Glu Leu Glu Glu Lys Asn Ile 
    130                 135                 140                 


Lys Glu Phe Leu Gln Ser Phe Val His Ile Val Gln Met Phe Ile Asn 
145                 150                 155                 160 


Thr Ser 
        


<210>  2
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  2

Met Val Leu Gly Thr Ile Asp Leu Cys Ser Cys Phe Ser Ala Gly Leu 
1               5                   10                  15      


Pro Lys Thr Glu Ala Asn Trp Val Asn Val Ile Ser Asp Leu Lys Lys 
            20                  25                  30          


Ile Glu Asp Leu Ile Gln Ser Met His Ile Asp Ala Thr Leu Tyr Thr 
        35                  40                  45              


Glu Ser Asp Val His Pro Ser Cys Lys Val Thr Ala Met Lys Cys Phe 
    50                  55                  60                  


Leu Leu Glu Leu Gln Val Ile Ser Leu Glu Ser Gly Asp Ala Ser Ile 
65                  70                  75                  80  


His Asp Thr Val Glu Asn Leu Ile Ile Leu Ala Asn Asn Ser Leu Ser 
                85                  90                  95      


Ser Asn Gly Asn Val Thr Glu Ser Gly Cys Lys Glu Cys Glu Glu Leu 
            100                 105                 110         


Glu Glu Lys Asn Ile Lys Glu Phe Leu Gln Ser Phe Val His Ile Val 
        115                 120                 125             


Gln Met Phe Ile Asn Thr Ser 
    130                 135 


<210>  3
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  3

Asn Trp Val Asn Val Ile Ser Asp Leu Lys Lys Ile Glu Asp Leu Ile 
1               5                   10                  15      


Gln Ser Met His Ile Asp Ala Thr Leu Tyr Thr Glu Ser Asp Val His 
            20                  25                  30          


Pro Ser Cys Lys Val Thr Ala Met Lys Cys Phe Leu Leu Glu Leu Gln 
        35                  40                  45              


Val Ile Ser Leu Glu Ser Gly Asp Ala Ser Ile His Asp Thr Val Glu 
    50                  55                  60                  


Asn Leu Ile Ile Leu Ala Asn Asn Ser Leu Ser Ser Asn Gly Asn Val 
65                  70                  75                  80  


Thr Glu Ser Gly Cys Lys Glu Cys Glu Glu Leu Glu Glu Lys Asn Ile 
                85                  90                  95      


Lys Glu Phe Leu Gln Ser Phe Val His Ile Val Gln Met Phe Ile Asn 
            100                 105                 110         


Thr Ser 
        


<210>  4
<211>  489
<212>  DNA
<213>  Homo sapiens

<400>  4
atgagaattt cgaaaccaca tttgagaagt atttccatcc agtgctactt gtgtttactt       60

ctaaacagtc attttctaac tgaagctggc attcatgtct tcattttggg ctgtttcagt      120

gcagggcttc ctaaaacaga agccaactgg gtgaatgtaa taagtgattt gaaaaaaatt      180

gaagatctta ttcaatctat gcatattgat gctactttat atacggaaag tgatgttcac      240

cccagttgca aagtaacagc aatgaagtgc tttctcttgg agttacaagt tatttcactt      300

gagtccggag atgcaagtat tcatgataca gtagaaaatc tgatcatcct agcaaacaac      360

agtttgtctt ctaatgggaa tgtaacagaa tctggatgca aagaatgtga ggaactggag      420

gaaaaaaata ttaaagaatt tttgcagagt tttgtacata ttgtccaaat gttcatcaac      480

acttcttga                                                              489


<210>  5
<211>  408
<212>  DNA
<213>  Homo sapiens

<400>  5
atggtattgg gaaccataga tttgtgcagc tgtttcagtg cagggcttcc taaaacagaa       60

gccaactggg tgaatgtaat aagtgatttg aaaaaaattg aagatcttat tcaatctatg      120

catattgatg ctactttata tacggaaagt gatgttcacc ccagttgcaa agtaacagca      180

atgaagtgct ttctcttgga gttacaagtt atttcacttg agtccggaga tgcaagtatt      240

catgatacag tagaaaatct gatcatccta gcaaacaaca gtttgtcttc taatgggaat      300

gtaacagaat ctggatgcaa agaatgtgag gaactggagg aaaaaaatat taaagaattt      360

ttgcagagtt ttgtacatat tgtccaaatg ttcatcaaca cttcttga                   408


<210>  6
<211>  345
<212>  DNA
<213>  Homo sapiens

<400>  6
aactgggtga atgtaataag tgatttgaaa aaaattgaag atcttattca atctatgcat       60

attgatgcta ctttatatac ggaaagtgat gttcacccca gttgcaaagt aacagcaatg      120

aagtgctttc tcttggagtt acaagttatt tcacttgagt ccggagatgc aagtattcat      180

gatacagtag aaaatctgat catcctagca aacaacagtt tgtcttctaa tgggaatgta      240

acagaatctg gatgcaaaga atgtgaggaa ctggaggaaa aaaatattaa agaatttttg      300

cagagttttg tacatattgt ccaaatgttc atcaacactt cttga                      345


<210>  7
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  7

Tyr Gly Arg Lys Lys Arg Arg Gln Arg Arg Arg 
1               5                   10      


<210>  8
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  8

Arg Arg Gln Arg Arg Thr Ser Lys Leu Met Lys Arg 
1               5                   10          


<210>  9
<211>  27
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  9

Gly Trp Thr Leu Asn Ser Ala Gly Tyr Leu Leu Gly Lys Ile Asn Leu 
1               5                   10                  15      


Lys Ala Leu Ala Ala Leu Ala Lys Lys Ile Leu 
            20                  25          


<210>  10
<211>  33
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  10

Lys Ala Leu Ala Trp Glu Ala Lys Leu Ala Lys Ala Leu Ala Lys Ala 
1               5                   10                  15      


Leu Ala Lys His Leu Ala Lys Ala Leu Ala Lys Ala Leu Lys Cys Glu 
            20                  25                  30          


Ala 
    


<210>  11
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  11

Arg Gln Ile Lys Ile Trp Phe Gln Asn Arg Arg Met Lys Trp Lys Lys 
1               5                   10                  15      


<210>  12
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  12

Arg Lys Lys Arg Arg Gln Arg Arg Arg 
1               5                   


<210>  13
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  13

Arg Lys Lys Arg Arg Gln Arg Arg 
1               5               


<210>  14
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  14

Tyr Ala Arg Ala Ala Ala Arg Gln Ala Arg Ala 
1               5                   10      


<210>  15
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  15

Thr His Arg Leu Pro Arg Arg Arg Arg Arg Arg 
1               5                   10      


<210>  16
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  16

Gly Gly Arg Arg Ala Arg Arg Arg Arg Arg Arg 
1               5                   10      


<210>  17
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  This residue may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  This stretch of residues may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  This residue may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  This residue may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  This residue may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  This residue may be repeated up to 20 times.

<400>  17

Gly Ser Gly Ser Gly 
1               5   


<210>  18
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  This stretch of residues may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  This residue may be repeated up to 20 times.

<400>  18

Gly Ser Gly Gly Ser 
1               5   


<210>  19
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  This stretch of residues may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  This residue may be repeated up to 20 times.

<400>  19

Gly Ser Gly Ser Gly 
1               5   


<210>  20
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(4)
<223>  This stretch of residues may be repeated up to 20 times.

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  This residue may be repeated up to 20 times.

<400>  20

Gly Gly Gly Ser 
1               


<210>  21
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  21

Gly Gly Ser Gly 
1               


<210>  22
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  22

Gly Gly Ser Gly Gly 
1               5   


<210>  23
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  23

Gly Ser Gly Gly Gly 
1               5   


<210>  24
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  24

Gly Gly Gly Ser Gly 
1               5   


<210>  25
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence

<400>  25

Gly Ser Ser Ser Gly 
1               5   


<210>  26
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  This stretch of residues may be repeated up to 50 times.

<400>  26

Gly Ser Gly Gly Ser 
1               5   


<210>  27
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(4)
<223>  This stretch of residues may be repeated up to 50 times.

<400>  27

Gly Gly Gly Ser 
1               


<210>  28
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Synthetic polypeptide sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  This stretch of residues may be repeated up to 50 times.

<400>  28

Gly Gly Gly Gly Ser 
1               5   


