                               SEQUENCE LISTING

<110> SANGAMO BIOSCIENCES, INC.
 
<120> GENE CORRECTION OF SCID-RELATED GENES IN HEMATOPOIETIC STEM AND 
      PROGENITOR CELLS

<130> 8325-0124.40

<140> PCT/US2015/042912
<141> 2015-07-30

<150> 62/030,942
<151> 2014-07-30

<160> 101   

<170> PatentIn version 3.5

<210> 1
<211> 25
<212> DNA
<213> Homo sapiens

<400> 1
ctgacctctt ctcttcctcc cacag                                             25


<210> 2
<211> 13
<212> DNA
<213> Homo sapiens

<400> 2
tttctctcca cag                                                          13


<210> 3
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 3
Trp Arg Ser Cys Arg Ser Ala 
1               5           


<210> 4
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 4
Asp Arg Ser Ala Leu Ser Arg 
1               5           


<210> 5
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 5
Gln Ser Gly Ser Leu Thr Arg 
1               5           


<210> 6
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 6
Asp Arg Ser His Leu Thr Arg 
1               5           


<210> 7
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 7
Arg Leu Asp Trp Leu Pro Met 
1               5           


<210> 8
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 8
Gln Ser Gly Asp Leu Thr Arg 
1               5           


<210> 9
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 9
Arg Arg Ala Asp Leu Ser Arg 
1               5           


<210> 10
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 10
Gln Arg Ser Asn Leu Asp Ser 
1               5           


<210> 11
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 11
Arg Ser Ala Asn Leu Ala Arg 
1               5           


<210> 12
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 12
Gln Ser Ala Asn Arg Thr Lys 
1               5           


<210> 13
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 13
Leu Arg His His Leu Thr Arg 
1               5           


<210> 14
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 14
Leu Arg His Asn Leu Arg Ala 
1               5           


<210> 15
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 15
Arg Ser Asp Ala Leu Ser Arg 
1               5           


<210> 16
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 16
Thr Ser Gly Asn Leu Thr Arg 
1               5           


<210> 17
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 17
Arg Ser Asp His Leu Ser Ala 
1               5           


<210> 18
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 18
Glu Ser Arg Tyr Leu Met Val 
1               5           


<210> 19
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 19
Gln Ser Gly His Leu Ala Arg 
1               5           


<210> 20
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 20
Arg Lys Trp Thr Leu Gln Gly 
1               5           


<210> 21
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 21
Arg Ser Asp Asp Leu Thr Arg 
1               5           


<210> 22
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 22
Asp Arg Ser Thr Arg Arg Gln 
1               5           


<210> 23
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 23
Gln Ser Ser Asp Leu Ser Arg 
1               5           


<210> 24
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 24
Gln Ser Asn Asp Leu Asn Ser 
1               5           


<210> 25
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 25
Arg Ser Asp Ser Leu Leu Arg 
1               5           


<210> 26
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 26
Gln Ser Tyr Asp Arg Phe Gln 
1               5           


<210> 27
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 27
Gln Ser Gly Asn Leu Ala Arg 
1               5           


<210> 28
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 28
Arg Ser Asp His Leu Ser Thr 
1               5           


<210> 29
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 29
Arg Ser Asp Ala Arg Thr Thr 
1               5           


<210> 30
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 30
Asp Arg Ser Thr Arg Ile Thr 
1               5           


<210> 31
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 31
Gln Asn Ala Thr Arg Ile Asn 
1               5           


<210> 32
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 32
Arg Met Tyr Thr Leu Ser Lys 
1               5           


<210> 33
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 33
Arg Ser Asp Ala Leu Ala Arg 
1               5           


<210> 34
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 34
Glu Arg Gly Thr Leu Ala Arg 
1               5           


<210> 35
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 35
Arg Ser Asp Ala Leu Thr Gln 
1               5           


<210> 36
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 36
Gln Ser Gly Ala Leu Ala Arg 
1               5           


<210> 37
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 37
His Lys Ser Ala Arg Ala Ala 
1               5           


<210> 38
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 38
Leu Leu His His Leu Asn Asn 
1               5           


<210> 39
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 39
Trp Arg Ile Ser Leu Ala Ala 
1               5           


<210> 40
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 40
Arg Ser Asp Asn Leu Ser Ala 
1               5           


<210> 41
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 41
Arg Ser Gln Asn Arg Thr Arg 
1               5           


<210> 42
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 42
Tyr Gln Gly Val Leu Thr Arg 
1               5           


<210> 43
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 43
Arg Ser Asp Asn Leu Arg Glu 
1               5           


<210> 44
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 44
Arg Ser Asp His Leu Ser Gln 
1               5           


<210> 45
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 45
Thr Ser Ala Asn Arg Thr Thr 
1               5           


<210> 46
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 46
Gln Ser Asn Gly Leu Thr Gln 
1               5           


<210> 47
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 47
ccctgggtgt agtctgtctg tgtcagga                                          28


<210> 48
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 48
atgaagagca agcgccatgt tgaagcca                                          28


<210> 49
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 49
ataagaggga tgtgaatggt aatgatgg                                          28


<210> 50
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 50
ctgcagctgc ccctgctggg agtggggc                                          28


<210> 51
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 51
ggccagtggc aggcaccaga tctctgta                                          28


<210> 52
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 52
ttacaatcat gtgggcagaa ttgaaaag                                          28


<210> 53
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 53
tgtaatggcc agtggcaggc accagatc                                          28


<210> 54
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 54
tcatgtgggc agaattgaaa agtggagt                                          28


<210> 55
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 55
tgattgtaat ggccagtggc aggcacca                                          28


<210> 56
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 56
gtgggcagaa ttgaaaagtg gagtggga                                          28


<210> 57
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 57
gccagtggca ggcaccagat ctctgtac                                          28


<210> 58
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 58
ttacaatcat gtgggcagaa ttgaaaag                                          28


<210> 59
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 59
gtacagagat ctggtgcctg c                                                 21


<210> 60
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 60
attctgccca catgattgta a                                                 21


<210> 61
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 61
Gln Arg Ser Asn Leu Val Arg 
1               5           


<210> 62
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 62
Thr Ser Gly Ser Leu Thr Arg 
1               5           


<210> 63
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 63
Gln Gly Cys Asn Leu Gly Lys 
1               5           


<210> 64
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 64
Asp Arg Ser Asn Leu Thr Arg 
1               5           


<210> 65
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 65
Trp Ser Thr Ser Leu Arg Ala 
1               5           


<210> 66
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 66
Trp Leu Ser Ser Leu Ser Ala 
1               5           


<210> 67
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 67
Asp Arg Ser Asn Leu Ser Arg 
1               5           


<210> 68
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 68
His Arg Gln His Leu Val Thr 
1               5           


<210> 69
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 69
Asp Arg Ser Thr Leu Arg Gln 
1               5           


<210> 70
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 70
Gln Ser Ser Asn Leu Ala Arg 
1               5           


<210> 71
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 71
Gln Gly Cys Asn Leu Val Lys 
1               5           


<210> 72
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 72
Leu Arg Gln Asn Leu Val Ala 
1               5           


<210> 73
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 73
His Arg His His Leu Gly Gln 
1               5           


<210> 74
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 74
Gln Asn Ala Thr Arg Thr Lys 
1               5           


<210> 75
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 75
Arg His Trp Ser Leu Ser Val 
1               5           


<210> 76
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 76
Gln Arg Thr Asn Leu Val Glu 
1               5           


<210> 77
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 77
Ala Ser Lys Thr Arg Thr Asn 
1               5           


<210> 78
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 78
Arg Ser Asp Val Leu Ser Thr 
1               5           


<210> 79
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 79
Ser Thr Ala Ala Leu Ser Tyr 
1               5           


<210> 80
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 80
Gln Leu Ala Asn Leu Gln Thr 
1               5           


<210> 81
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (28)..(28)
<223> a, c, t, g, unknown or other

<400> 81
tgtgtacaga ctaagttgaa gatgttan                                          28


<210> 82
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 82
ttccaagtaa taactgtgtg ctcaagtg                                          28


<210> 83
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 83
cttttatgac ccatttggaa gaaataaa                                          28


<210> 84
<211> 28
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 84
atgataaagc tgcaaaccca aagaaact                                          28


<210> 85
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 85
cacatgattg taatggccag tgg                                               23


<210> 86
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 86
ttctgcccac atgattgtaa tgg                                               23


<210> 87
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 87
cactggccat tacaatcatg tgg                                               23


<210> 88
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 88
ttgagcacac agttattact tgg                                               23


<210> 89
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 89
tcttccaaat gggtcataaa agg                                               23


<210> 90
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 90
ctgcgctcaa ggctggagct tgg                                               23


<210> 91
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 91
cccagactag tgattagctg tgg                                               23


<210> 92
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 92
tcccagctcc ttggatggaa tgg                                               23


<210> 93
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 93
aaccgctacc ctggtattgc tgg                                               23


<210> 94
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 94
taattctgta gtaagtaagc agg                                               23


<210> 95
<211> 23
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 95
aatatacaac tgagggagac agg                                               23


<210> 96
<211> 9
<212> PRT
<213> Unknown

<220>
<223> Description of Unknown: "LAGLIDADG" family 
      homing endonuclease peptide

<400> 96
Leu Ala Gly Leu Ile Asp Ala Asp Gly 
1               5                   


<210> 97
<211> 7
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 97
Asn Pro Ala Asn Leu Thr Arg 
1               5           


<210> 98
<211> 5
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 98
Thr Gly Glu Lys Pro 
1               5   


<210> 99
<211> 5
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 99
Thr Gly Glu Arg Gly 
1               5   


<210> 100
<211> 6
<212> PRT
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      peptide

<400> 100
Thr Gly Ser Gln Lys Pro 
1               5       


<210> 101
<211> 800
<212> DNA
<213> Homo sapiens

<400> 101
gcccgtgtca cacagcacat atttgccaca ccctctgtaa agccctggtt tataaggttc       60

tttccaccgg aagctatgac agaggaaacg tgtgggtggg gaggggtagt gggtgaggga      120

cccaggttcc tgacacagac agactacacc cagggaatga agagcaagcg ccatgttgaa      180

gccatcatta ccattcacat ccctcttatt cctgcagctg cccctgctgg gagtggggct      240

gaacacgaca attctgacgc ccaatgggaa tgaagacacc acagctggtg ggaaatctgg      300

gactggaggg ggctggtgag aagggtggct gtgggaaggg gccgtacaga gatctggtgc      360

ctgccactgg ccattacaat catgtgggca gaattgaaaa gtggagtggg aagggcaagg      420

gggagggttc cctgcctcac gctacttctt ctttctttct tgtttgtttg tttctttctt      480

tcttttgagg cagggtctca ctatgttgcc taggctggtc tcaaactcct ggcctctagt      540

gatcctcctg cctcagcctt tcaaagcacc aggattacag acatgagcca ccgtgcttgg      600

cctcctcctt ctgaccatca tttctctttc cctccctgcc ttcattttct ccccaatcta      660

gatttcttcc tgaccactat gcccactgac tccctcagtg tttccactct gcccctccca      720

gaggttcagt gttttgtgtt caatgtcgag tacatgaatt gcacttggaa cagcagctct      780

gagccccagc ctaccaacct                                                  800



