                         SEQUENCE LISTING

<110>  APTUS BIOTECH, S.L.
 
<120>  APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOF

<130>  P9923PC00

<150>  P201430955
<151>  2014-06-24

<160>  7     

<170>  PatentIn version 3.5

<210>  1
<211>  45
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  TLRApt#1R-T aptamer with the capability of binding specifically 
       to and inhibiting TLR-4

<400>  1
ccggcacggg acaaggcgcg ggacggcgta gatcaggtcg acacc                       45


<210>  2
<211>  59
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  TLRApt#4F-T aptamer with the capability of binding specifically 
       to and inhibiting TLR-4

<400>  2
ggtgtgccaa taaaccatat cgccgcgtta gcatgtactc ggttggccct aaatacgag        59


<210>  3
<211>  78
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  TLRApt#1R aptamer with the capability of binding specifically to 
       and inhibiting TLR-4

<400>  3
gttgctcgta tttagggcca ccggcacggg acaaggcgcg ggacggcgta gatcaggtcg       60

acaccagtct tcatccgc                                                     78


<210>  4
<211>  76
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  TLRApt#4F aptamer with the capability of binding specifically to 
       and inhibiting TLR-4

<400>  4
gcggatgaag actggtgtgc caataaacca tatcgccgcg ttagcatgta ctcggttggc       60

cctaaatacg agcaac                                                       76


<210>  5
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer for amplifying aptamers

<400>  5
gcggatgaag actggtgt                                                     18


<210>  6
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Primer for amplifying aptamers

<400>  6
gttgctcgta tttagggc                                                     18


<210>  7
<211>  76
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Nonspecific sequence that is not able to adopt any secondary 
       structure

<400>  7
agagagagag agagagagag agagagagag agagagagag agagagagag agagagagag       60

agagagagag agagag                                                       76


