                               SEQUENCE LISTING

<110> UNIVERSITY OF MASSACHUSETTS
 
<120> EXOSOMAL LOADING USING HYDROPHOBICALLY MODIFIED OLIGONUCLEOTIDES

<130> 122274-14020

<140> PCT/US2015/026350
<141> 2015-04-17

<150> 61/981,722
<151> 2014-04-18

<160> 6     

<170> PatentIn version 3.5

<210> 1
<211> 13
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(2) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (6)..(6) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (8)..(8) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (11)..(13) 
<223> 2'-O-methyl nucleotide

<220>
<221> misc_feature
<222> (11)..(13) 
<223> Phosphorothioate linkage

<400> 1
acaaauacga uua                                                          13


<210> 2
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<223> 5' Phosphate

<220>
<221> modified_base
<222> (1)..(1) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (4)..(5) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (7)..(7) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (9)..(11) 
<223> 2'-Fluoro nucleotide

<220>
<221> misc_feature
<222> (13)..(19) 
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (14)..(14) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (17)..(18) 
<223> 2'-O-methyl nucleotide

<400> 2
uaaucguauu ugucaauca                                                    19


<210> 3
<211> 15
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(2) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (4)..(4) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (12)..(15) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (13)..(15) 
<223> Phosphorothioate linkage

<400> 3
caguaaagag auuaa                                                        15


<210> 4
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<223> 5' Phosphate

<220>
<221> modified_base
<222> (1)..(1) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (2)..(2) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (5)..(11) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (13)..(14) 
<223> 2'-Fluoro nucleotide

<220>
<221> misc_feature
<222> (14)..(20) 
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (17)..(17) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (19)..(19) 
<223> 2'-Fluoro nucleotide

<400> 4
uuaaucucuu uacugauaua                                                   20


<210> 5
<211> 15
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(2) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (4)..(4) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (12)..(15) 
<223> 2'-O-methyl nucleotide

<220>
<221> misc_feature
<222> (13)..(15) 
<223> Phosphorothioate linkage

<400> 5
caguaaagag auuaa                                                        15


<210> 6
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<223> 5' Phosphate

<220>
<221> modified_base
<222> (1)..(1) 
<223> 2'-O-methyl nucleotide

<220>
<221> modified_base
<222> (2)..(2) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (5)..(11) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (13)..(14) 
<223> 2'-Fluoro nucleotide

<220>
<221> misc_feature
<222> (14)..(20) 
<223> Phosphorothioate linkage

<220>
<221> modified_base
<222> (17)..(17) 
<223> 2'-Fluoro nucleotide

<220>
<221> modified_base
<222> (19)..(19) 
<223> 2'-Fluoro nucleotide

<400> 6
uuaaucucuu uacugauaua                                                   20


