                               SEQUENCE LISTING

<110> ARCTURUS THERAPEUTICS, INC.

<120> UNA OLIGOMERS HAVING REDUCED OFF-TARGET EFFECTS IN GENE
      SILENCING

<130> ARC1246WO

<140>
<141>

<150> 61/970,320
<151> 2014-03-25

<160> 83    

<170> PatentIn version 3.5

<210> 1
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 1
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 2
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 2
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 3
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 3
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 4
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 4
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 5
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 5
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 6
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(21)
<223> a, c, u, g, unknown or other

<400> 6
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 7
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(22)
<223> a, c, u, g, unknown or other

<400> 7
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 8
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 8
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 9
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(22)
<223> a, c, u, g, unknown or other

<400> 9
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 10
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(21)
<223> a, c, u, g, unknown or other

<400> 10
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 11
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 11
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 12
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 12
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 13
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 13
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 14
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(21)
<223> a, c, u, g, unknown or other

<400> 14
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 15
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(22)
<223> a, c, u, g, unknown or other

<400> 15
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 16
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 16
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 17
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 17
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 18
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 18
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 19
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 19
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 20
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(21)
<223> a, c, u, g, unknown or other

<400> 20
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 21
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(22)
<223> a, c, u, g, unknown or other

<400> 21
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 22
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 22
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 23
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(22)
<223> a, c, u, g, unknown or other

<400> 23
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 24
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(21)
<223> a, c, u, g, unknown or other

<400> 24
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 25
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 25
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 26
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(21)
<223> a, c, u, g, unknown or other

<400> 26
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 27
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(22)
<223> UNA monomer

<400> 27
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 28
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 28
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 29
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(22)
<223> a, c, u, g, unknown or other

<400> 29
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 30
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(21)
<223> UNA monomer

<400> 30
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 31
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(22)
<223> a, c, u, g, unknown or other

<400> 31
nnnnnnnnnn nnnnnnnnnn nn                                                22


<210> 32
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (2)..(8)
<223> UNA monomer

<220>
<221> modified_base
<222> (9)..(21)
<223> a, c, u, g, unknown or other

<400> 32
nnnnnnnnnn nnnnnnnnnn n                                                 21


<210> 33
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 33
aaaagggaca guauucucau u                                                 21


<210> 34
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 34
ugagaauacu gucccuuuuu u                                                 21


<210> 35
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 35
caauaaagcu ggacaagaau u                                                 21


<210> 36
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 36
uucuugucca gcuuuauugu u                                                 21


<210> 37
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 37
auguaaccaa gaguauuccu u                                                 21


<210> 38
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 38
ggaauacucu ugguuacauu u                                                 21


<210> 39
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(2)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 39
auguaaccaa gaguauuccu u                                                 21


<210> 40
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 40
ggaauacucu ugguuacauu u                                                 21


<210> 41
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (3)..(3)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 41
auguaaccaa gaguauuccu u                                                 21


<210> 42
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 42
ggaauacucu ugguuacauu u                                                 21


<210> 43
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(2)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 43
auguaaccaa gaguauuccu u                                                 21


<210> 44
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 44
ggaauacucu ugguuacauu u                                                 21


<210> 45
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-24 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-24 sense oligonucleotide

<400> 45
guaaccaaga guauuccaut t                                                 21


<210> 46
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-91 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-91 sense oligonucleotide

<400> 46
guaaccaaga guauuccaut t                                                 21


<210> 47
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-14 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATX-14 sense oligonucleotide

<400> 47
guaaccaaga guauuccaut t                                                 21


<210> 48
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-16 sense oligonucleotide


<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 48
guaaccaaga guauuccauu u                                                 21


<210> 49
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-13 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATX-13 sense oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<400> 49
guaaccaaga guauuccaut t                                                 21


<210> 50
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-15 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATX-15 sense oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<400> 50
guaaccaaga guauuccaut t                                                 21


<210> 51
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-17 sense oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 51
guaaccaaga guauuccauu u                                                 21


<210> 52
<211> 20
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-21 sense oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (19)..(19)
<223> Non-nucleotide monomer

<400> 52
guaaccaaga guauuccauu                                                   20


<210> 53
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-92 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-92 sense oligonucleotide

<400> 53
auguaaccaa gaguauucct t                                                 21


<210> 54
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-25 sense oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> Non-nucleotide monomer

<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 54
auguaaccaa gaguauuccu u                                                 21


<210> 55
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-24 antisense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-24 antisense oligonucleotide

<400> 55
auggaauacu cuugguuact t                                                 21


<210> 56
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-91 antisense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-91 antisense oligonucleotide

<400> 56
auggaauacu cuugguuact t                                                 21


<210> 57
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-14 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 57
auggaauacu cuugguuacu u                                                 21


<210> 58
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-16 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 58
auggaauacu cuugguuacu u                                                 21


<210> 59
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-13 antisense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATX-13 antisense oligonucleotide

<400> 59
auggaauacu cuugguuact t                                                 21


<210> 60
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-15 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 60
auggaauacu cuugguuacu u                                                 21


<210> 61
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-17 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(21)
<223> Non-nucleotide monomer

<400> 61
auggaauacu cuugguuacu u                                                 21


<210> 62
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-21 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 62
auggaauacu cuugguuacu u                                                 21


<210> 63
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-92 antisense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-92 antisense oligonucleotide

<400> 63
ggaauacucu ugguuacaut t                                                 21


<210> 64
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-25 antisense oligonucleotide


<220>
<221> modified_base
<222> (20)..(20)
<223> Non-nucleotide monomer

<400> 64
ggaauacucu ugguuacauu u                                                 21


<210> 65
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 65
gtaaccaaga gtattccat                                                    19


<210> 66
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 66
tattccatat tccatattcc a                                                 21


<210> 67
<211> 19
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 67
atggaatact cttggttac                                                    19


<210> 68
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 68
ttggttattg gttattggtt a                                                 21


<210> 69
<211> 27
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      target oligonucleotide

<400> 69
cauguaacca agaguauucc auuuuua                                           27


<210> 70
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-92 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-92 sense oligonucleotide

<400> 70
auguaaccaa gaguauucct t                                                 21


<210> 71
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-25 sense oligonucleotide

<400> 71
auguaaccaa gaguauuccu u                                                 21


<210> 72
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-104 oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-104 oligonucleotide

<400> 72
uguaaccaag aguauuccat t                                                 21


<210> 73
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-37 oligonucleotide

<400> 73
uguaaccaag aguauuccau u                                                 21


<210> 74
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-91 sense oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-91 sense oligonucleotide

<400> 74
guaaccaaga guauuccaut t                                                 21


<210> 75
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-21 sense oligonucleotide

<400> 75
guaaccaaga guauuccauu u                                                 21


<210> 76
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-105 oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-105 oligonucleotide

<400> 76
uaaccaagag uauuccauut t                                                 21


<210> 77
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-38 oligonucleotide

<400> 77
uaaccaagag uauuccauuu u                                                 21


<210> 78
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATS-106 oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      ATS-106 oligonucleotide

<400> 78
ccaagaguau uccauuuuut t                                                 21


<210> 79
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      ATX-39 oligonucleotide

<400> 79
ccaagaguau uccauuuuuu u                                                 21


<210> 80
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, t, g, unknown or other

<400> 80
nnnnnnnnnn nnnnnnnnnt t                                                 21


<210> 81
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220>
<223> Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, t, g, unknown or other

<400> 81
nnnnnnnnnn nnnnnnnnnt t                                                 21


<210> 82
<211> 22
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(1)
<223> UNA monomer

<220>
<221> modified_base
<222> (2)..(20)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (21)..(21)
<223> UNA monomer

<400> 82
nnnnnnnnnn nnnnnnnnnn nu                                                22


<210> 83
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide


<220>
<221> modified_base
<222> (1)..(19)
<223> a, c, u, g, unknown or other

<220>
<221> modified_base
<222> (20)..(20)
<223> UNA monomer

<400> 83
nnnnnnnnnn nnnnnnnnnn u                                                 21


