                         SEQUENCE LISTING

<110>  Midatech Limited
 
<120>  Nanoparticle-insulin and Insulin Analogue Compositions

<130>  CSC/FP7098858

<150>  GB 1401706.5
<151>  2014-01-31

<160>  5     

<170>  PatentIn version 3.3

<210>  1
<211>  21
<212>  PRT
<213>  Homo sapiens

<220>
<221>  DISULFID
<222>  (7)..(7)
<223>  Interchain disulphide bond between Cys7 of SEQ ID NO: 1 and Cys7 
       of SEQ ID NO: 2

<220>
<221>  DISULFID
<222>  (20)..(20)
<223>  Interchain disulphide bond between Cys20 of SEQ ID NO: 1 and 
       Cys19 of SEQ ID NO: 2

<400>  1

Gly Ile Val Glu Gln Cys Cys Thr Ser Ile Cys Ser Leu Tyr Gln Leu 
1               5                   10                  15      


Glu Asn Tyr Cys Asn 
            20      


<210>  2
<211>  30
<212>  PRT
<213>  Homo sapiens

<220>
<221>  DISULFID
<222>  (7)..(7)
<223>  Interchain disulphide bond between Cys7 of SEQ ID NO: 1 and Cys7 
       of SEQ ID NO: 2

<220>
<221>  DISULFID
<222>  (19)..(19)
<223>  Interchain disulphide bond between Cys20 of SEQ ID NO: 1 and 
       Cys19 of SEQ ID NO: 2

<400>  2

Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr 
1               5                   10                  15      


Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro Lys Thr 
            20                  25                  30  


<210>  3
<211>  30
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Synthetic sequence: Insulin lispro, a fast-acting insulin 
       analogue

<400>  3

Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr 
1               5                   10                  15      


Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Lys Pro Thr 
            20                  25                  30  


<210>  4
<211>  30
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Synthetic sequence: Insulin aspart, a fast-acting insulin 
       analogue

<400>  4

Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr 
1               5                   10                  15      


Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Asp Lys Thr 
            20                  25                  30  


<210>  5
<211>  30
<212>  PRT
<213>  Artificial sequence

<220>
<223>  Synthetic sequence: Insulin glulisine, a fast-acting insulin 
       analogue

<400>  5

Phe Val Lys Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr 
1               5                   10                  15      


Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro Glu Thr 
            20                  25                  30  

