                         SEQUENCE LISTING

<110>  The Regents of the University of California
 
<120>  TARGETS IN PULMONARY ARTERIAL HYPERTENSION

<130>  24978-0245

<150>  US 61/860,503
<151>  2013-07-31

<160>  40    

<170>  PatentIn version 3.5

<210>  1
<211>  540
<212>  PRT
<213>  human

<400>  1

Met Asn Ser Thr Gly His Leu Gln Asp Ala Pro Asn Ala Thr Ser Leu 
1               5                   10                  15      


His Val Pro His Ser Gln Glu Gly Asn Ser Thr Ser Leu Gln Glu Gly 
            20                  25                  30          


Leu Gln Asp Leu Ile His Thr Ala Thr Leu Val Thr Cys Thr Phe Leu 
        35                  40                  45              


Leu Ala Val Ile Phe Cys Leu Gly Ser Tyr Gly Asn Phe Ile Val Phe 
    50                  55                  60                  


Leu Ser Phe Phe Asp Pro Ala Phe Arg Lys Phe Arg Thr Asn Phe Asp 
65                  70                  75                  80  


Phe Met Ile Leu Asn Leu Ser Phe Cys Asp Leu Phe Ile Cys Gly Val 
                85                  90                  95      


Thr Ala Pro Met Phe Thr Phe Val Leu Phe Phe Ser Ser Ala Ser Ser 
            100                 105                 110         


Ile Pro Asp Ala Phe Cys Phe Thr Phe His Leu Thr Ser Ser Gly Phe 
        115                 120                 125             


Ile Ile Met Ser Leu Lys Thr Val Ala Val Ile Ala Leu His Arg Leu 
    130                 135                 140                 


Arg Met Val Leu Gly Lys Gln Pro Asn Arg Thr Ala Ser Phe Pro Cys 
145                 150                 155                 160 


Thr Val Leu Leu Thr Leu Leu Leu Trp Ala Thr Ser Phe Thr Pro Ala 
                165                 170                 175     


Thr Leu Ala Thr Leu Lys Thr Ser Lys Ser His Leu Cys Leu Pro Met 
            180                 185                 190         


Ser Ser Leu Ile Ala Gly Lys Gly Lys Ala Ile Leu Ser Leu Tyr Val 
        195                 200                 205             


Val Asp Phe Thr Phe Cys Val Ala Val Val Ser Val Ser Tyr Ile Met 
    210                 215                 220                 


Ile Ala Gln Thr Leu Arg Lys Asn Ala Gln Val Arg Lys Cys Pro Pro 
225                 230                 235                 240 


Val Ile Thr Val Asp Ala Ser Arg Pro Gln Pro Phe Met Gly Val Pro 
                245                 250                 255     


Val Gln Gly Gly Gly Asp Pro Ile Gln Cys Ala Met Pro Ala Leu Tyr 
            260                 265                 270         


Arg Asn Gln Asn Tyr Asp Lys Leu Gln His Val Gln Thr Arg Gly Tyr 
        275                 280                 285             


Thr Lys Ser Pro Asn Gln Leu Val Thr Pro Ala Ala Ser Arg Leu Gln 
    290                 295                 300                 


Leu Val Ser Ala Ile Asn Leu Ser Thr Ala Lys Asp Ser Lys Ala Val 
305                 310                 315                 320 


Val Thr Cys Val Ile Ile Val Leu Ser Val Leu Val Cys Cys Leu Pro 
                325                 330                 335     


Leu Gly Ile Ser Leu Val Gln Val Val Leu Ser Ser Asn Gly Ser Phe 
            340                 345                 350         


Ile Leu Tyr Gln Phe Glu Leu Phe Gly Phe Thr Leu Ile Phe Phe Lys 
        355                 360                 365             


Ser Gly Leu Asn Pro Phe Ile Tyr Ser Arg Asn Ser Ala Gly Leu Arg 
    370                 375                 380                 


Arg Lys Val Leu Trp Cys Leu Gln Tyr Ile Gly Leu Gly Phe Phe Cys 
385                 390                 395                 400 


Cys Lys Gln Lys Thr Arg Leu Arg Ala Met Gly Lys Gly Asn Leu Glu 
                405                 410                 415     


Val Asn Arg Asn Lys Ser Ser His His Glu Thr Asn Ser Ala Tyr Met 
            420                 425                 430         


Leu Ser Pro Lys Pro Gln Lys Lys Phe Val Asp Gln Ala Cys Gly Pro 
        435                 440                 445             


Ser His Ser Lys Glu Ser Met Val Ser Pro Lys Ile Ser Ala Gly His 
    450                 455                 460                 


Gln His Cys Gly Gln Ser Ser Ser Thr Pro Ile Asn Thr Arg Ile Glu 
465                 470                 475                 480 


Pro Tyr Tyr Ser Ile Tyr Asn Ser Ser Pro Ser Gln Glu Glu Ser Ser 
                485                 490                 495     


Pro Cys Asn Leu Gln Pro Val Asn Ser Phe Gly Phe Ala Asn Ser Tyr 
            500                 505                 510         


Ile Ala Met His Tyr His Thr Thr Asn Asp Leu Val Gln Glu Tyr Asp 
        515                 520                 525             


Ser Thr Ser Ala Lys Gln Ile Pro Val Pro Ser Val 
    530                 535                 540 


<210>  2
<211>  18
<212>  PRT
<213>  human

<400>  2

Pro Asn Ala Thr Ser Leu His Val Pro His Ser Gln Glu Gly Asn Ser 
1               5                   10                  15      


Thr Ser 
       
<210>  3
<211>  20
<212>  DNA
<213>  human

<400>  3
acccagagga cagcaatgac                                                   20


<210>  4
<211>  20
<212>  DNA
<213>  human

<400>  4
cagagctcca tcttcagcct                                                   20


<210>  5
<211>  20
<212>  DNA
<213>  human

<400>  5
tccagggaga gaacatttgg                                                   20


<210>  6
<211>  20
<212>  DNA
<213>  human

<400>  6
agtaccaggg agcgacttga                                                   20


<210>  7
<211>  21
<212>  DNA
<213>  human

<400>  7
cgatatgcac aattgtctcc a                                                 21


<210>  8
<211>  20
<212>  DNA
<213>  human

<400>  8
ttccttaaga gctggactgg                                                   20


<210>  9
<211>  20
<212>  DNA
<213>  human

<400>  9
tctccaacat gtcccatcac                                                   20


<210>  10
<211>  20
<212>  DNA
<213>  human

<400>  10
atggaagtcg agccacatct                                                   20


<210>  11
<211>  20
<212>  DNA
<213>  human

<400>  11
ctcaggtcca gcttctccag                                                   20


<210>  12
<211>  18
<212>  DNA
<213>  human

<400>  12
ccttctgcct aacggcac                                                     18


<210>  13
<211>  20
<212>  DNA
<213>  human

<400>  13
gcaggccagg tttttaatga                                                   20


<210>  14
<211>  19
<212>  DNA
<213>  human

<400>  14
tgtaccgcca gttcaccac                                                    19


<210>  15
<211>  22
<212>  DNA
<213>  human

<400>  15
gacctgtact tttctactgg cg                                                22


<210>  16
<211>  21
<212>  DNA
<213>  human

<400>  16
gctgtcactc cacaaatgaa g                                                 21


<210>  17
<211>  20
<212>  DNA
<213>  human

<400>  17
atgtgctggc gttttcagag                                                   20


<210>  18
<211>  17
<212>  DNA
<213>  human

<400>  18
aggccagctg gagcgtc                                                      17


<210>  19
<211>  20
<212>  DNA
<213>  human

<400>  19
ccaggagtcc agcagatgat                                                   20


<210>  20
<211>  20
<212>  DNA
<213>  human

<400>  20
tgtctcggca tagttctgga                                                   20


<210>  21
<211>  20
<212>  DNA
<213>  mouse

<400>  21
aagaggctct gtgggactga                                                   20


<210>  22
<211>  20
<212>  DNA
<213>  mouse

<400>  22
taccaccttg gccagtaagg                                                   20


<210>  23
<211>  20
<212>  DNA
<213>  mouse

<400>  23
aggagcaaga tgcaggaaaa                                                   20


<210>  24
<211>  20
<212>  DNA
<213>  mouse

<400>  24
caccttcgtg ctgttcttca                                                   20


<210>  25
<211>  20
<212>  DNA
<213>  human

<400>  25
cacgagttcg tggaagaggt                                                   20


<210>  26
<211>  20
<212>  DNA
<213>  human

<400>  26
ttcttcgtgc agatgtggag                                                   20


<210>  27
<211>  20
<212>  DNA
<213>  human

<400>  27
ggggatctaa ggtggcattt                                                   20


<210>  28
<211>  18
<212>  DNA
<213>  human

<400>  28
ccgcctgctt cagtctgt                                                     18


<210>  29
<211>  20
<212>  DNA
<213>  rat

<400>  29
tggtcagatg aagggtgtga                                                   20


<210>  30
<211>  20
<212>  DNA
<213>  rat

<400>  30
ccggtaaata accaggcaga                                                   20


<210>  31
<211>  20
<212>  DNA
<213>  rat

<400>  31
gcggtcaacc tctctactgc                                                   20


<210>  32
<211>  20
<212>  DNA
<213>  human

<400>  32
gcaccagagc actttccttc                                                   20


<210>  33
<211>  20
<212>  DNA
<213>  human

<400>  33
gcaacagagg atgacgatga                                                   20


<210>  34
<211>  20
<212>  DNA
<213>  human

<400>  34
ggagtacctg aaccccaaca                                                   20


<210>  35
<211>  19
<212>  DNA
<213>  human

<400>  35
gctgcacctc gatcatctg                                                    19


<210>  36
<211>  17
<212>  DNA
<213>  human

<400>  36
ctggctatgc gtgctgg                                                      17


<210>  37
<211>  20
<212>  DNA
<213>  human

<400>  37
gtaacccgtt gaaccccatt                                                   20


<210>  38
<211>  20
<212>  DNA
<213>  human

<400>  38
ccatccaatc ggtagtagcg                                                   20


<210>  39
<211>  20
<212>  DNA
<213>  human

<400>  39
gcctagcagc cgacttagaa                                                   20


<210>  40
<211>  20
<212>  DNA
<213>  human

<400>  40
aaatcacatc gcgtcaacac                                                   20


