                                SEQUENCE LISTING

<110> The Regents of the University of California

<120> Functional Illumination in Living Cells
  

<130> 76916-904726

<140> WO PCT/US14/31824   
<141> 2014-03-26  

<150> US 61/05,320        
<151> 2013-03-26  

<150> US 61/837,392       
<151> 2013-06-20  

<160> 228

<170> FastSEQ for Windows Version 4.0

<210> 1
<211> 22
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(4)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (5)...(9)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (12)...(14)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (13)...(13)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (15)...(19)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (20)...(22)
<223> Xaa = any amino acid

<400> 1
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa Xaa Xaa
            20          


<210> 2
<211> 22
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(3)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (4)...(8)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (11)...(13)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (12)...(12)
<223> Thr can be phosphorylated

<220> 
<221> VARIANT        
<222> (14)...(18)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (19)...(22)
<223> Xaa = any amino acid

<400> 2
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Arg Arg Xaa Thr Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa Xaa Xaa
            20          


<210> 3
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(5)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (6)...(10)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (11)...(11)
<223> Ser may be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (13)...(17)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (18)...(21)
<223> Xaa = any amino acid

<400> 3
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa Xaa
            20      


<210> 4
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(5)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (6)...(10)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (11)...(11)
<223> Thr can be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (13)...(17)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (18)...(21)
<223> Xaa = any amino acid

<400> 4
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Thr Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa Xaa
            20      


<210> 5
<211> 20
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(4)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (5)...(9)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (10)...(10)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (13)...(17)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (18)...(20)
<223> Xaa = any amino acid

<400> 5
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Pro Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa
            20  


<210> 6
<211> 20
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (1)...(4)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (5)...(9)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (10)...(10)
<223> Thr can be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (13)...(17)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> VARIANT        
<222> (18)...(20)
<223> Xaa = any amino acid

<400> 6
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Thr Pro Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa
            20  


<210> 7
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for histone modification enzyme

<220> 
<221> MOD_RES        
<222> (2)...(2)
<223> Lys can be acetylated or methylated

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated

<220> 
<221> PHOSPHORYLATION
<222> (4)...(5)
<223> Thr can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> MOD_RES        
<222> (18)...(18)
<223> Lys can be acetylated or methylated

<400> 7
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 8
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for histone modification enzyme

<220> 
<221> VARIANT        
<222> (1)...(1)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (2)...(10)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (13)...(13)
<223> Ser can be phosphorylated

<220> 
<221> MOD_RES        
<222> (14)...(14)
<223> Lys can be acetylated or methylated

<220> 
<221> PHOSPHORYLATION
<222> (16)...(16)
<223> Thr can be phosphorylated

<400> 8
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ala Arg Thr Lys Gln Thr
 1               5                  10                  15      
Ala Arg
        

<210> 9
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for histone modification enzyme

<220> 
<221> VARIANT        
<222> (1)...(1)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (2)...(10)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> PHOSPHORYLATION
<222> (11)...(11)
<223> Ser can be phosphorylated

<220> 
<221> MOD_RES        
<222> (15)...(15)
<223> Lys can be acetylated or methylated

<400> 9
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Gly Arg Gly Lys Gln
 1               5                  10                  15      
Gly
    

<210> 10
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> VARIANT        
<222> (2)...(11)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> MOD_RES        
<222> (12)...(12)
<223> Glu affixed to polyethylene glycol grafted
      polystyrene bead

<400> 10
Asp Xaa Xaa Xaa Xaa Gly Xaa Xaa Xaa Xaa Xaa Glu
 1               5                  10          


<210> 11
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #1

<400> 11
Cys Asn Ser Pro Asp Ile Cys
 1               5          


<210> 12
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #3

<400> 12
Cys Gln Pro Asp Leu Thr Cys
 1               5          


<210> 13
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #6

<400> 13
Cys Gly Asn Thr Glu Pro Cys
 1               5          


<210> 14
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #8

<400> 14
Cys Met Thr Gln Glu Ala Cys
 1               5          


<210> 15
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #11

<400> 15
Cys Leu Ser Asp Glu Phe Cys
 1               5          


<210> 16
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #4

<400> 16
Cys His Thr His Ile Leu Cys
 1               5          


<210> 17
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #5

<400> 17
Cys His Pro Leu Leu Pro Cys
 1               5          


<210> 18
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #9

<400> 18
Cys Glu Ile His Arg Ile Cys
 1               5          


<210> 19
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #2

<400> 19
Cys Leu Met Asn Lys Trp Cys
 1               5          


<210> 20
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #7

<400> 20
Cys Tyr Lys Trp Trp Val Cys
 1               5          


<210> 21
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of bead #10

<400> 21
Cys Lys Trp Ile Leu Pro Cys
 1               5          


<210> 22
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 1

<400> 22
Asp Ile Leu Asp Asp Gly Asp Glu Ile Gln Gly Glu
 1               5                  10          


<210> 23
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 2

<400> 23
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 24
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 3

<400> 24
Asp Arg Asp Gly Asp Gly Asp His Arg Lys Ile Glu
 1               5                  10          


<210> 25
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 4

<400> 25
Asp Ser Asp Ser Trp Gly Glu Tyr Phe His Glu Glu
 1               5                  10          


<210> 26
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 5

<400> 26
Asp Phe Met Arg Gln Gly Val Tyr Asp Ile Pro Glu
 1               5                  10          


<210> 27
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 6

<400> 27
Asp Asp Tyr Asp Asp Gly Trp Ile Tyr Glu Phe Glu
 1               5                  10          


<210> 28
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 8

<400> 28
Asp Gly Asp Asp Gly Gly Tyr Trp Pro Phe Pro Glu
 1               5                  10          


<210> 29
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 10

<400> 29
Asp Glu Trp His Asp Gly Met Glu Gly Asn Leu Glu
 1               5                  10          


<210> 30
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 11

<400> 30
Asp Ser Lys Asp Pro Gly Met Thr His Leu Lys Glu
 1               5                  10          


<210> 31
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 12

<400> 31
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 32
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 13

<400> 32
Asp Ala Gln Trp Met Gly Ala Asn Met His Thr Glu
 1               5                  10          


<210> 33
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic amino acid linker

<400> 33
Gly Gly Ser Gly Ser Gly Gly Ser
 1               5              


<210> 34
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide insert for dORF2 gene of
      baculovirus transfer vector encoding Hepatitis E
      viral particles

<400> 34
Asp Ser Asp Ser Gln Gly Glu Tyr Phe His Glu Glu
 1               5                  10          


<210> 35
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic peptide substrate for protein tyrosine
      kinases Btk, Etk and Src

<400> 35
Tyr Ile Tyr Gly Ser Phe Lys
 1               5          


<210> 36
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of linear one-bead-one-compound
      (OBOC) combinatorial library L-1

<220> 
<221> VARIANT        
<222> (1)...(13)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 36
Xaa Xaa Tyr Ile Tyr Gly Ser Phe Lys Xaa Xaa Xaa Xaa Cys
 1               5                  10                  


<210> 37
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide of cyclic one-bead-one-compound
      (OBOC) combinatorial library L-2

<220> 
<221> VARIANT        
<222> (2)...(14)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 37
Cys Xaa Xaa Tyr Ile Tyr Gly Ser Phe Lys Xaa Xaa Xaa Xaa Cys
 1               5                  10                  15  


<210> 38
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic phosphorylated peptide substrate for
      protein tyrosine kinases Btk, Etk and Src

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> phosphorylated Tyr

<400> 38
Tyr Ile Tyr Gly Ser Phe Lys
 1               5          


<210> 39
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 1 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 39
Asp Asp Tyr Ile Tyr Gly Ser Phe Lys Pro Tyr Ile Ala Cys
 1               5                  10                  


<210> 40
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 2 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 40
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Asn Asp Tyr Ile Cys
 1               5                  10                  


<210> 41
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 3 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 41
Asp Asn Tyr Ile Tyr Gly Ser Phe Lys Pro Trp Glu Trp Cys
 1               5                  10                  


<210> 42
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 4 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 42
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Tyr Trp Pro Ala Cys
 1               5                  10                  


<210> 43
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 5 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 43
Asp Thr Tyr Ile Tyr Gly Ser Phe Lys Val Asn Pro Asp Cys
 1               5                  10                  


<210> 44
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic phosphorylated peptide substrate for
      protein tyrosine kinases Btk, Etk and Src and
      protein kinase A (PKA)

<220> 
<221> VARIANT        
<222> (3)...(3)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Ser

<400> 44
Arg Arg Xaa Ser
 1              


<210> 45
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide from
      cyclic library L-4

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphorylated Ser

<400> 45
Cys Met Gly Arg Arg Pro Ser Val Asp Asn Asn Cys
 1               5                  10          


<210> 46
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide from
      cyclic library L-4

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphorylated Ser

<400> 46
Cys Gly Val Arg Arg Asp Ser Trp Trp Tyr Asp Cys
 1               5                  10          


<210> 47
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 1 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 47
Asp Asp Tyr Ile Tyr Gly Ser Phe Lys Pro Tyr Ile Ala Cys
 1               5                  10                  


<210> 48
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 2 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 48
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Asn Asp Tyr Ile Cys
 1               5                  10                  


<210> 49
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 3 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 49
Asp Asn Tyr Ile Tyr Gly Ser Phe Lys Pro Trp Glu Trp Cys
 1               5                  10                  


<210> 50
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 4 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Tyr

<400> 50
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Tyr Trp Pro Ala Cys
 1               5                  10                  


<210> 51
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 5 from
      linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> phosphorylated Ser

<400> 51
Asp Thr Tyr Ile Tyr Gly Ser Phe Lys Val Asn Pro Asp Cys
 1               5                  10                  


<210> 52
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 1-D from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Tyr

<400> 52
Asp Tyr Ile Tyr Gly Ser Phe Lys Pro Tyr Ile Ala Cys
 1               5                  10              


<210> 53
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 2-D from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Tyr

<400> 53
Val Tyr Ile Tyr Gly Ser Phe Lys Asn Asp Tyr Ile Cys
 1               5                  10              


<210> 54
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 3-D from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Tyr

<400> 54
Asn Tyr Ile Tyr Gly Ser Phe Lys Pro Trp Glu Trp Cys
 1               5                  10              


<210> 55
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 4-D from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Tyr

<400> 55
Val Tyr Ile Tyr Gly Ser Phe Lys Tyr Trp Pro Ala Cys
 1               5                  10              


<210> 56
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 5-D from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> phosphorylated Tyr

<400> 56
Thr Tyr Ile Tyr Gly Ser Phe Lys Val Asn Pro Asp Cys
 1               5                  10              


<210> 57
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 1-P from linear library L-1

<400> 57
Asp Asp Tyr Ile Tyr Gly Ser Phe Lys Pro Tyr Ile Ala Cys
 1               5                  10                  


<210> 58
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 2-P
      from linear library L-1

<400> 58
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Asn Asp Tyr Ile Cys
 1               5                  10                  


<210> 59
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 3-P
      from linear library L-1

<400> 59
Asp Asn Tyr Ile Tyr Gly Ser Phe Lys Pro Trp Glu Trp Cys
 1               5                  10                  


<210> 60
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 4-P from linear library L-1

<400> 60
Asp Val Tyr Ile Tyr Gly Ser Phe Lys Tyr Trp Pro Ala Cys
 1               5                  10                  


<210> 61
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide 5-P from linear library L-1

<400> 61
Asp Thr Tyr Ile Tyr Gly Ser Phe Lys Val Asn Pro Asp Cys
 1               5                  10                  


<210> 62
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 1C
      from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 62
Cys Asp Asp Tyr Ile Tyr Gly Ser Phe Lys Pro Tyr Ile Ala Cys
 1               5                  10                  15  


<210> 63
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 2C
      from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 63
Cys Asp Val Tyr Ile Tyr Gly Ser Phe Lys Asn Asp Tyr Ile Cys
 1               5                  10                  15  


<210> 64
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 3C
      from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 64
Cys Asp Asn Tyr Ile Tyr Gly Ser Phe Lys Asn Pro Trp Glu Trp Cys
 1               5                  10                  15      


<210> 65
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 4C
      from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 65
Cys Asp Val Tyr Ile Tyr Gly Ser Phe Lys Tyr Trp Pro Ala Cys
 1               5                  10                  15  


<210> 66
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding peptide 5C
      from linear library L-1

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> phosphorylated Tyr

<400> 66
Cys Asp Thr Tyr Ile Tyr Gly Ser Phe Lys Val Asn Pro Asp Cys
 1               5                  10                  15  


<210> 67
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide with N-terminal 6 amino acids of
      histone H3

<220> 
<221> VARIANT        
<222> (1)...(4)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphphorylated Thr

<220> 
<221> METHYLATION    
<222> (8)...(8)
<223> Lys unmethylated or methylated 1-3 times

<400> 67
Xaa Xaa Xaa Xaa Ala Arg Thr Lys Gln Thr
 1               5                  10  


<210> 68
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide with N-terminal histone H2 tail

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phophorylated Ser

<220> 
<221> ACETYLATION    
<222> (11)...(11)
<223> acetylated Lys

<400> 68
Asp Pro Ser Trp Pro Asn Ser Gly Arg Gly Lys
 1               5                  10      


<210> 69
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide with N-terminal histone H2 tail

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphorylated Ser

<220> 
<221> ACETYLATION    
<222> (11)...(11)
<223> acetylated Lys

<400> 69
Thr Arg Pro Ser Met Trp Ser Gly Arg Gly Lys
 1               5                  10      


<210> 70
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide with N-terminal histone H2 tail

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphorylated Ser

<220> 
<221> ACETYLATION    
<222> (11)...(11)
<223> acetylated Lys

<400> 70
Val Trp Asp Gly Ile Arg Ser Gly Arg Gly Lys
 1               5                  10      


<210> 71
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide substrate for protein kinase

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> phosphorylated Ser

<400> 71
Gly Leu Phe Asp Gln Glu Ser Gly Arg Gly Lys
 1               5                  10      


<210> 72
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide for protein kinase A (PKA)

<220> 
<221> MOD_RES        
<222> (1)...(9)
<223> Xaa = any amino acid

<400> 72
Xaa Xaa Xaa Arg Arg Xaa Ser Xaa Xaa
 1               5                  


<210> 73
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide for protein kinase JNK

<220> 
<221> VARIANT        
<222> (1)...(10)
<223> Xaa = any amino acid

<400> 73
Xaa Xaa Xaa Xaa Xaa Thr Pro Xaa Xaa Xaa
 1               5                  10  


<210> 74
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide linear library

<220> 
<221> VARIANT        
<222> (2)...(11)
<223> Xaa = any amino acid

<400> 74
Asp Xaa Xaa Xaa Xaa Gly Xaa Xaa Xaa Xaa Xaa Glu
 1               5                  10          


<210> 75
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H2 peptide fusion library

<220> 
<221> VARIANT        
<222> (1)...(1)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (9)...(10)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<220> 
<221> PHOSPHORYLATION
<222> (11)...(11)
<223> Ser can be phosphorylated or unphosphorylated

<220> 
<221> ACETYLATION    
<222> (15)...(15)
<223> Lys can be acetylated

<400> 75
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ser Gly Arg Gly Lys Gln
 1               5                  10                  15      
Gly
    

<210> 76
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion library

<220> 
<221> METHYLATION    
<222> (2)...(2)
<223> Arg can be methylated

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Thr can be phosphorylated

<220> 
<221> MOD_RES        
<222> (4)...(4)
<223> Lys can be methylated or acetylated

<220> 
<221> MOD_RES        
<222> (9)...(9)
<223> Lys can be methylated or acetylated

<220> 
<221> PHOSPHORYLATION
<222> (10)...(10)
<223> Ser can be phosphorylated

<220> 
<221> PHOSPHORYLATION
<222> (11)...(11)
<223> Thr can be phosphorylated

<220> 
<221> ACETYLATION    
<222> (14)...(14)
<223> Lys may be acetuylated

<220> 
<221> METHYLATION    
<222> (17)...(17)
<223> Arg can be methylated

<220> 
<221> MOD_RES        
<222> (18)...(18)
<223> Lys can be methylated or acetylated

<400> 76
Ala Arg Thr Lys Gln Thr Ala Arg Lys Ser Thr Gly Gly Lys Ala Pro
 1               5                  10                  15      
Arg Lys Gln Leu Ala
            20      


<210> 77
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> METHYLATION    
<222> (2)...(2)
<223> Lys unmethylated or methylated 1-3 times

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated or unphosphorylated

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Thr can be phosphorylated or unphosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<220> 
<221> METHYLATION    
<222> (18)...(18)
<223> Lys unmethylated or methylated 1-3 times

<400> 77
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 78
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 2

<220> 
<221> VARIANT        
<222> (1)...(1)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (2)...(10)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<220> 
<221> PHOSPHORYLATION
<222> (13)...(13)
<223> Thr can be phosphorylated or unphosphorylated

<220> 
<221> METHYLATION    
<222> (14)...(14)
<223> Lys unmethylated or methylated 1-3 times

<400> 78
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Ala Arg Thr Lys Gln Thr
 1               5                  10                  15      
Ala Arg
        


<210> 79
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 12

<400> 79
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 80
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 80
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr Thr Ala
 1               5                  10          


<210> 81
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 81
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr Ala Glu
 1               5                  10          


<210> 82
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 82
Asp Trp Trp Asp Trp Gly Asn His Gly Ala Thr Glu
 1               5                  10          


<210> 83
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 83
Asp Trp Trp Asp Trp Gly Asn His Ala Tyr Thr Glu
 1               5                  10          


<210> 84
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 84
Asp Trp Trp Asp Trp Gly Asn Ala Gly Tyr Thr Glu
 1               5                  10          


<210> 85
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 85
Asp Trp Trp Asp Trp Gly Ala His Gly Tyr Thr Glu
 1               5                  10          


<210> 86
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 86
Asp Trp Trp Asp Trp Ala Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 87
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 87
Asp Trp Trp Asp Ala Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 88
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 88
Asp Trp Trp Ala Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 89
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 89
Asp Trp Ala Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 90
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 90
Asp Ala Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 91
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk

<400> 91
Ala Trp Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10          


<210> 92
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 92
Trp Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10      


<210> 93
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 93
Trp Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  10  


<210> 94
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 94
Asp Trp Gly Asn His Gly Tyr Thr Glu
 1               5                  


<210> 95
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 95
Trp Gly Asn His Gly Tyr Thr Glu
 1               5              


<210> 96
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 96
Gly Asn His Gly Tyr Thr Glu
 1               5          


<210> 97
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 97
Asn His Gly Tyr Thr Glu
 1               5      


<210> 98
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 98
Gly Tyr Thr Glu
 1              


<210> 99
<211> 3
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 variant from alanine walk,
      Peptide 12 deletion

<400> 99
Tyr Thr Glu
 1          


<210> 100
<211> 3
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 100
Asp Trp Trp
 1          


<210> 101
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 101
Asp Trp Trp Asp
 1              


<210> 102
<211> 5
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 102
Asp Trp Trp Asp Trp
 1               5  


<210> 103
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 103
Asp Trp Trp Asp Trp Gly
 1               5      


<210> 104
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 104
Asp Trp Trp Asp Trp Gly Asn
 1               5          


<210> 105
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 105
Asp Trp Trp Asp Trp Gly Asn His
 1               5              


<210> 106
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 106
Asp Trp Trp Asp Trp Gly Asn His Gly
 1               5                  


<210> 107
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 107
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr
 1               5                  10  


<210> 108
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 12 deletion

<400> 108
Asp Trp Trp Asp Trp Gly Asn His Gly Tyr Thr
 1               5                  10      


<210> 109
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) malachite green (MG) binding Peptide 2 from
      alanine walk

<400> 109
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 110
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 110
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu Glu Ala
 1               5                  10          


<210> 111
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 111
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu Ala Glu
 1               5                  10          


<210> 112
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 112
Asp Trp Trp Trp Asp Gly Phe Glu Arg Ala Glu Glu
 1               5                  10          


<210> 113
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 113
Asp Trp Trp Trp Asp Gly Phe Glu Ala Leu Glu Glu
 1               5                  10          


<210> 114
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 114
Asp Trp Trp Trp Asp Gly Phe Ala Arg Leu Glu Glu
 1               5                  10          


<210> 115
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 115
Asp Trp Trp Trp Asp Gly Ala Glu Arg Leu Glu Glu
 1               5                  10          


<210> 116
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 116
Asp Trp Trp Trp Asp Ala Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 117
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 117
Asp Trp Trp Trp Ala Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 118
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 118
Asp Trp Trp Ala Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 119
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 119
Asp Trp Ala Trp Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 120
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 120
Asp Ala Trp Trp Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 121
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 variant from alanine walk

<400> 121
Ala Trp Trp Trp Asp Gly Phe Glu Arg Leu Glu Glu
 1               5                  10          


<210> 122
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 122
Asp Trp Trp Trp Asp Phe Glu Arg Leu Glu Glu
 1               5                  10      


<210> 123
<211> 3
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 123
Leu Glu Glu
 1          


<210> 124
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 124
Arg Leu Glu Glu
 1              


<210> 125
<211> 5
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 125
Glu Arg Leu Glu Glu
 1               5  


<210> 126
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 126
Phe Glu Arg Leu Glu Glu
 1               5      


<210> 127
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 127
Gly Phe Glu Arg Leu Glu Glu
 1               5          


<210> 128
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 128
Asp Gly Phe Glu Arg Leu Glu Glu
 1               5              


<210> 129
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 129
Trp Asp Phe Glu Arg Leu Glu Glu
 1               5              


<210> 130
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 130
Trp Trp Asp Phe Glu Arg Leu Glu Glu
 1               5                  


<210> 131
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 131
Trp Trp Trp Asp Phe Glu Arg Leu Glu Glu
 1               5                  10  


<210> 132
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 132
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu Glu
 1               5                  10      


<210> 133
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 133
Asp Trp Trp Trp Asp Gly Phe Glu Arg Leu
 1               5                  10  


<210> 134
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 134
Asp Trp Trp Trp Asp Gly Phe Glu Arg
 1               5                  


<210> 135
<211> 8
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 135
Asp Trp Trp Trp Asp Gly Phe Glu
 1               5              


<210> 136
<211> 7
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 136
Asp Trp Trp Trp Asp Gly Phe
 1               5          


<210> 137
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 137
Asp Trp Trp Trp Asp Gly
 1               5      


<210> 138
<211> 5
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 138
Asp Trp Trp Trp Asp
 1               5  


<210> 139
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) Peptide 2 deletion

<400> 139
Asp Trp Trp Trp
 1              


<210> 140
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) linear OBOC library L-1, cyclic OBOC library L-2

<220> 
<221> VARIANT        
<222> (1)...(13)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Tyr can be phosphorylated

<400> 140
Xaa Xaa Tyr Ile Tyr Gly Ser Phe Lys Xaa Xaa Xaa Xaa Cys
 1               5                  10                  


<210> 141
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) linear OBOC library L-1

<220> 
<221> VARIANT        
<222> (1)...(13)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Tyr can be phosphorylated

<220> 
<221> MOD_RES        
<222> (15)...(15)
<223> 3-nitrotyrosine

<400> 141
Xaa Xaa Tyr Ile Tyr Gly Ser Phe Lys Xaa Xaa Xaa Xaa Cys Tyr
 1               5                  10                  15  


<210> 142
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) cyclic OBOC library L-2

<220> 
<221> DISULFID       
<222> (1)...(15)

<220> 
<221> VARIANT        
<222> (2)...(14)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> Tyr can be phosphorylated

<220> 
<221> MOD_RES        
<222> (16)...(16)
<223> 3-nitrotyrosine

<400> 142
Cys Xaa Xaa Tyr Ile Tyr Gly Ser Phe Lys Xaa Xaa Xaa Xaa Cys Tyr
 1               5                  10                  15      


<210> 143
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) linear OBOC library L-3

<220> 
<221> VARIANT        
<222> (1)...(10)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> Ser can be phosphorylated

<400> 143
Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa Xaa Cys
 1               5                  10      


<210> 144
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) linear OBOC library L-3

<220> 
<221> VARIANT        
<222> (1)...(10)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (6)...(6)
<223> Ser can be phosphorylated

<220> 
<221> MOD_RES        
<222> (12)...(12)
<223> 3-nitrotyrosine

<400> 144
Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa Xaa Cys Tyr
 1               5                  10          


<210> 145
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) cyclic OBOC library L-4

<220> 
<221> DISULFID       
<222> (1)...(12)

<220> 
<221> VARIANT        
<222> (2)...(11)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> Ser can be phosphorylated

<400> 145
Cys Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa Xaa Cys
 1               5                  10          


<210> 146
<211> 13
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) cyclic OBOC library L-4

<220> 
<221> DISULFID       
<222> (1)...(12)

<220> 
<221> VARIANT        
<222> (2)...(11)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> PHOSPHORYLATION
<222> (13)...(13)
<223> Ser can be phophorylated

<220> 
<221> MOD_RES        
<222> (13)...(13)
<223> 3-nitrotyrosine

<400> 146
Cys Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa Xaa Cys Tyr
 1               5                  10              


<210> 147
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(12)
<223> Xaa = any amino acid

<220> 
<221> MOD_RES        
<222> (12)...(12)
<223> Xaa affixed to polyethylene glycol grafted
      polystyrene bead

<400> 147
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10          


<210> 148
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(6)
<223> Xaa = any amino acid

<400> 148
Xaa Xaa Xaa Xaa Xaa Xaa
 1               5      


<210> 149
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(11)
<223> Xaa = any amino acid

<220> 
<221> MOD_RES        
<222> (11)...(11)
<223> Xaa affixed to polyethylene glycol grafted
      polystyrene bead

<400> 149
Xaa Xaa Xaa Xaa Xaa Ser Pro Xaa Xaa Xaa Xaa
 1               5                  10      


<210> 150
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(12)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (8)...(8)
<223> Ser can be phosphorylated

<220> 
<221> MOD_RES        
<222> (12)...(12)
<223> Xaa affixed to polyethylene glycol grafted
      polystyrene bead

<400> 150
Xaa Xaa Xaa Xaa Arg Arg Xaa Ser Xaa Xaa Xaa Xaa
 1               5                  10          


<210> 151
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(10)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Ser can be phosphorylated

<220> 
<221> MOD_RES        
<222> (10)...(10)
<223> Xaa affixed to polyethylene glycol grafted
      polystyrene bead

<400> 151
Xaa Xaa Xaa Xaa Ser Pro Xaa Xaa Xaa Xaa
 1               5                  10  


<210> 152
<211> 20
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> MOD_RES        
<222> (2)...(2)
<223> Lys can be acetylated or methylated

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> MOD_RES        
<222> (18)...(18)
<223> Lys can be acetylated or methylated

<220> 
<221> MOD_RES        
<222> (20)...(20)
<223> Pro affixed to polyethylene glycol grafted
      polystyrene bead

<400> 152
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro
            20  


<210> 153
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> VARIANT        
<222> (1)...(4)
<223> Xaa = any amino acid

<220> 
<221> PHOSPHORYLATION
<222> (7)...(7)
<223> Thr can be phosphorylated

<220> 
<221> METHYLATION    
<222> (8)...(8)
<223> Lys can be methylated

<220> 
<221> MOD_RES        
<222> (10)...(10)
<223> Thr affixed to polyethylene glycol grafted
      polystyrene bead

<400> 153
Xaa Xaa Xaa Xaa Ala Arg Thr Lys Gln Thr
 1               5                  10  


<210> 154
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X6-1 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 154
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Tyr Phe Gly Val His Ser
 1               5                  10                  15  


<210> 155
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter for c-src protein tyrosine
      kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 155
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Glu Ser Val Tyr Ile Glu
 1               5                  10                  15  


<210> 156
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X7-6 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 156
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Tyr Phe Asn Ala Ile Asn Thr
 1               5                  10                  15      


<210> 157
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter for c-src protein tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 157
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asn Tyr His Tyr Glu Ile Glu
 1               5                  10                  15      
Tyr
    

<210> 158
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X8-2 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 158
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asn Tyr Thr Trp Tyr Val Ser
 1               5                  10                  15      
Tyr
    

<210> 159
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter for c-src protein tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 159
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Gln Glu Phe Thr Ala Phe
 1               5                  10                  15      
Met
    

<210> 160
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X9-1 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 160
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Arg Met Phe Thr Thr Trp
 1               5                  10                  15      
Ser Asp
        

<210> 161
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter for c-src protein tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 161
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Phe Met Leu Trp Met Asp Glu
 1               5                  10                  15      
Thr Tyr
        

<210> 162
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter for c-src protein tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 162
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Phe Met Leu Trp Met Asp Glu
 1               5                  10                  15      
Thr Tyr Gly
            

<210> 163
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 163
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Thr Phe Glu Leu
 1               5                  10                  15      
Thr
    

<210> 164
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 164
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Gly Tyr Trp Gly Trp
 1               5                  10                  15      
Phe Thr Phe
            

<210> 165
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide LLT4

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 165
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Leu Tyr Ile Met Asp
 1               5                  10                  15      
Gly Trp Phe
            

<210> 166
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Ser can be phosphorylated

<400> 166
Leu Arg Arg Ala Ser Leu Pro Phe Met Met Leu Trp Leu Trp Ser Lys
 1               5                  10                  15      


<210> 167
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Ser can be phosphorylated

<400> 167
Leu Arg Arg Ala Ser Leu Arg Glu Ile Phe Val Ser Glu Trp Met
 1               5                  10                  15  


<210> 168
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 168
Arg Pro Tyr Gln Ile Lys Asp Gln Ser Val Asn Ile
 1               5                  10          


<210> 169
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 169
Gln Ala Phe Arg Tyr Glu Arg Asp Arg Trp Glu Arg
 1               5                  10          


<210> 170
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 170
Asp Asp Ala Ile Thr Gly Arg Tyr Ser Ile Gly Glu
 1               5                  10          


<210> 171
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 171
Asp Phe Asp Tyr Tyr Gly Pro Thr Met Trp Ser Glu
 1               5                  10          


<210> 172
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 172
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Thr Phe Glu Leu
 1               5                  10                  15      
Thr
    

<210> 173
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 173
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Phe Phe Gln Gly Tyr
 1               5                  10                  15      
Trp Phe
        

<210> 174
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 174
Leu Arg Arg Ala Ser Leu Phe Tyr Gly Met Trp Tyr Pro Ser Thr
 1               5                  10                  15  


<210> 175
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 175
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Pro Val Trp Phe Phe Arg Trp
 1               5                  10                  15      


<210> 176
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 176
Ile Tyr Gly Ser Phe Lys Lys Lys Pro Val Trp Phe Phe Arg Trp
 1               5                  10                  15  


<210> 177
<211> 14
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 177
Tyr Gly Ser Phe Lys Lys Lys Pro Val Trp Phe Phe Arg Trp
 1               5                  10                  


<210> 178
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 178
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Val Val Asp Thr His Tyr Gln
 1               5                  10                  15      
Glu
    

<210> 179
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 179
Ile Tyr Gly Ser Phe Lys Lys Lys Val Val Asp Thr His Tyr Gln Glu
 1               5                  10                  15      


<210> 180
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 180
Tyr Gly Ser Phe Lys Lys Lys Val Val Asp Thr His Tyr Gln Glu
 1               5                  10                  15  


<210> 181
<211> 11
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 181
Asp Ala Ile Thr Gly Arg Tyr Ser Ile Gly Glu
 1               5                  10      


<210> 182
<211> 10
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 182
Ala Ile Thr Gly Arg Tyr Ser Ile Gly Glu
 1               5                  10  


<210> 183
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (1)...(2)
<223> Xaa = Glu, Asp or absent

<220> 
<221> VARIANT        
<222> (3)...(4)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (5)...(7)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (8)...(8)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (9)...(9)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (10)...(10)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (11)...(11)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = Glu or Asp

<400> 183
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10          


<210> 184
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (1)...(2)
<223> Xaa = Glu, Asp or absent

<220> 
<221> VARIANT        
<222> (3)...(10)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = Glu or Asp

<400> 184
Xaa Xaa Xaa Xaa Thr Gly Arg Xaa Ser Xaa Gly Xaa
 1               5                  10          


<210> 185
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (1)...(5)
<223> Xaa = Asp, Ala, Tyr or Trp, where at least one can
      be Asp and at least one can be Trp

<220> 
<221> VARIANT        
<222> (6)...(11)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<400> 185
Xaa Xaa Xaa Xaa Xaa Gly Xaa Xaa Xaa Xaa Xaa Glu
 1               5                  10          


<210> 186
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (2)...(5)
<223> Xaa = Asp, Ala, Tyr or Trp, where at least one can
      be Trp

<220> 
<221> VARIANT        
<222> (6)...(11)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<400> 186
Asp Xaa Xaa Xaa Xaa Gly Xaa Xaa Xaa Xaa Xaa Glu
 1               5                  10          


<210> 187
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<220> 
<221> VARIANT        
<222> (10)...(15)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (16)...(19)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys,
      Pro or absent

<400> 187
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa
            

<210> 188
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(17)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (18)...(19)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys,
      Pro or absent

<400> 188
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa
            

<210> 189
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> PHOSPHORYLATION
<222> (5)...(5)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(14)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (15)...(16)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys,
      Pro or absent

<400> 189
Leu Arg Arg Ala Ser Leu Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      


<210> 190
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 190
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Tyr Phe Gly Val His Ser
 1               5                  10                  15  


<210> 191
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 191
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Glu Ser Val Tyr Ile Glu
 1               5                  10                  15  


<210> 192
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 192
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Tyr Phe Asn Ala Ile Asn Thr
 1               5                  10                  15      


<210> 193
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 193
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asn Tyr His Tyr Glu Ile Glu
 1               5                  10                  15      
Tyr
    

<210> 194
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 194
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asn Tyr Thr Trp Tyr Val Ser
 1               5                  10                  15      
Tyr
    

<210> 195
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 195
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Gln Glu Phe Thr Ala Phe
 1               5                  10                  15      
Met
    

<210> 196
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 196
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Arg Met Phe Thr Thr Trp
 1               5                  10                  15      
Ser Asp
        

<210> 197
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 197
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Phe Met Leu Trp Met Asp Glu
 1               5                  10                  15      
Thr Tyr
        

<210> 198
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 198
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Phe Met Leu Trp Met Asp Glu
 1               5                  10                  15      
Thr Tyr Gly
            

<210> 199
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 199
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Thr Phe Glu Leu
 1               5                  10                  15      
Thr
    

<210> 200
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 200
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Gly Tyr Trp Gly Trp
 1               5                  10                  15      
Phe Thr Phe
            

<210> 201
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 201
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Leu Tyr Ile Met Asp
 1               5                  10                  15      
Gly Trp Phe
            

<210> 202
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 202
Leu Arg Arg Ala Ser Leu Pro Phe Met Met Leu Trp Leu Trp Ser Lys
 1               5                  10                  15      


<210> 203
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 203
Leu Arg Arg Ala Ser Leu Arg Glu Ile Phe Val Ser Glu Trp Met
 1               5                  10                  15  


<210> 204
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<400> 204
Asp Ala Tyr Trp Asp Gly Thr Gly His Ile Tyr Glu
 1               5                  10          


<210> 205
<211> 6
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide OBOC library

<220> 
<221> VARIANT        
<222> (1)...(6)
<223> Xaa = any amino acid

<220> 
<221> MOD_RES        
<222> (6)...(6)
<223> Xaa affixed to polyethylene glycol grafted
      polystyrene bead

<400> 205
Xaa Xaa Xaa Xaa Xaa Xaa
 1               5      


<210> 206
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 206
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 207
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated or unphosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 207
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 208
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<220> 
<221> ACETYLATION    
<222> (18)...(18)
<223> Lys can be acetylated

<400> 208
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 209
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> ACETYLATION    
<222> (2)...(2)
<223> Lys can be acetylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 209
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 210
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<220> 
<221> ACETYLATION    
<222> (18)...(18)
<223> Lys can be acetylated

<400> 210
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 211
<211> 21
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide histone H3 peptide fusion Library 1

<220> 
<221> ACETYLATION    
<222> (2)...(2)
<223> Lys can be acetylated

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 211
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro Arg
            20      


<210> 212
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (1)...(2)
<223> Xaa = Asp or absent

<220> 
<221> VARIANT        
<222> (3)...(4)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (5)...(7)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (8)...(8)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (9)...(9)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (10)...(10)
<223> Xaa = Val, Leu, Ile, Met, Phe, Gly, Ala, Ser, Thr,
      Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (11)...(11)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<400> 212
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Glu
 1               5                  10          


<210> 213
<211> 12
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide

<220> 
<221> VARIANT        
<222> (1)...(5)
<223> Xaa = Asn, Glu, Gln, His, Lys, Arg, Ala, Asp, Tyr,
      Trp or Pro

<220> 
<221> VARIANT        
<222> (6)...(11)
<223> Xaa = Val, Leu, Ile, Met, Phe, Asn, Glu, Gln, His,
      Lys, Arg, Asp, Gly, Ala, Ser, Thr, Tyr, Trp, Cys or Pro

<220> 
<221> VARIANT        
<222> (12)...(12)
<223> Xaa = Asp or Glu

<400> 213
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10          


<210> 214
<211> 5
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic H3 histone tail

<400> 214
Arg Lys Ser Thr Gly
 1               5  


<210> 215
<211> 5
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic H3 histone tail

<400> 215
Gly Lys Ala Pro Arg
 1               5  


<210> 216
<211> 18
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide library substrate for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<220> 
<221> VARIANT        
<222> (10)...(15)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (16)...(18)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 216
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa
        

<210> 217
<211> 20
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide library c-abl motif (Abltide)

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<220> 
<221> VARIANT        
<222> (12)...(17)
<223> Xaa = any natural amino acid except Cys

<220> 
<221> VARIANT        
<222> (18)...(20)
<223> Xaa = any natural amino acid except Cys, may be
      present or absent

<400> 217
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Xaa Xaa Xaa Xaa
            20  


<210> 218
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X6-3 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 218
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Glu Gln Tyr Tyr Gln Trp
 1               5                  10                  15  


<210> 219
<211> 16
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X7-1 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 219
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Tyr Val Phe Ala Leu Tyr
 1               5                  10                  15      


<210> 220
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X8-1 for c-src protein
      tyrosine kinase

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 220
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Ile Phe Thr Gln Asn Ile Tyr
 1               5                  10                  15      
Ile
    

<210> 221
<211> 17
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide reporter X8-3 for c-src protein
      tyrosine kinase

<400> 221
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys Asp Gln Glu Phe Thr Ala Phe
 1               5                  10                  15      
Met
    

<210> 222
<211> 9
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic peptide substrate for protein tyrosine
      kinase c-src

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Tyr can be phosphorylated

<400> 222
Tyr Ile Tyr Gly Ser Phe Lys Lys Lys
 1               5                  


<210> 223
<211> 4
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic protein kinase A (PKA) substrate motif

<220> 
<221> VARIANT        
<222> (3)...(3)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (4)...(4)
<223> Xaa = Ser or Thr

<400> 223
Arg Arg Xaa Xaa
 1              


<210> 224
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide LLT1

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 224
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Tyr Val Tyr Asp
 1               5                  10                  15      
Met His Ile
            

<210> 225
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide LLT2

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 225
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Tyr Val Gln Asp
 1               5                  10                  15      
Ser Arg Ala
            

<210> 226
<211> 19
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide LLT3

<220> 
<221> PHOSPHORYLATION
<222> (4)...(4)
<223> Tyr can be phosphorylated

<400> 226
Glu Ala Ile Tyr Ala Ala Pro Phe Ala Lys Lys Tyr Tyr Val Ser Glu
 1               5                  10                  15      
Arg Lys Trp
            

<210> 227
<211> 15
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) peptide activator of malachite green (MG)

<400> 227
Leu Arg Arg Ala Ser Leu Phe Tyr Gly Met Trp Tyr Pro Ser Thr
 1               5                  10                  15  


<210> 228
<211> 20
<212> PRT
<213> Artificial Sequence

<220> 
<223> synthetic genetically encoded small illuminant
      (GESI) OBOC library

<220> 
<221> METHYLATION    
<222> (2)...(2)
<223> Lys can be methylated

<220> 
<221> PHOSPHORYLATION
<222> (3)...(3)
<223> Ser can be phosphorylated

<220> 
<221> VARIANT        
<222> (7)...(7)
<223> Xaa = any amino acid

<220> 
<221> VARIANT        
<222> (8)...(16)
<223> Xaa = any amino acid, may be present or absent

<220> 
<221> ACETYLATION    
<222> (18)...(18)
<223> Lys can be acetylated

<220> 
<221> MOD_RES        
<222> (20)...(20)
<223> Pro affixed to polyethylene glycol grafted
      polystyrene bead

<400> 152
Arg Lys Ser Thr Thr Gly Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa
 1               5                  10                  15      
Gly Lys Ala Pro
            20  


