                         SEQUENCE LISTING

<110>  Universitt Bern
 
<120>  TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM

<130>  uz143fwo

<160>  21    

<170>  PatentIn version 3.5

<210>  1
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis

<400>  1
aactgtcacg                                                              10


<210>  2
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymidine and the other substituents being 
       hydrogen

<400>  2
aactgtcacg                                                              10


<210>  3
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<400>  3
aactgtcacg                                                              10


<210>  4
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<400>  4
aactgtcacg                                                              10


<210>  5
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<400>  5
aactgtcacg                                                              10


<210>  6
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<400>  6
aactgtcacg                                                              10


<210>  7
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<400>  7
aactgtcacg                                                              10


<210>  8
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<400>  8
aactgtcacg                                                              10


<210>  9
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<400>  9
aactgtcacg                                                              10


<210>  10
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z2 being F and the other 
       substituents being hydrogen

<400>  10
aactgtcacg                                                              10


<210>  11
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z2 being F and the other 
       substituents being hydrogen

<400>  11
aactgtcacg                                                              10


<210>  12
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z2 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z2 being F and the other 
       substituents being hydrogen

<400>  12
aactgtcacg                                                              10


<210>  13
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<400>  13
aactgtcacg                                                              10


<210>  14
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<400>  14
aactgtcacg                                                              10


<210>  15
<211>  10
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<400>  15
aactgtcacg                                                              10


<210>  16
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis

<400>  16
gcatttttac cg                                                           12


<210>  17
<211>  12
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, z1 being F and the other 
       substituents being hydrogen

<400>  17
gcatttttac cg                                                           12


<210>  18
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being cytosine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine and the other substituents being 
       hydrogen

<400>  18
aacctcggct tacct                                                        15


<210>  19
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 being 
       phosphate, T2 being phosphorothioate, Bx being adenine and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being adenine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being guanine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being guanine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being adenine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being cytosine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine and the other substituents 
       being hydrogen

<400>  19
aacctcggct tacct                                                        15


<210>  20
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methlycytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methlycytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methylcytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being guanine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methylcytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being adenine and the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methylcytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being 5' methylcytosine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<400>  20
aacctcggct tacct                                                        15


<210>  21
<211>  15
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Sequence for biophysical analysis


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  tricyclic nucleoside according to fomula I with T1 being 
       phosphate, T2 being phosphorothioate, Bx being adenine and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (2)..(2)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being adenine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5' methlycytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5' methlycytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (5)..(5)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (6)..(6)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5' methylcytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being guanine the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being guanine the other substituents being 
       hydrogen

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5'methylcytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being adenine and the other substituents 
       being hydrogen

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5' methylcytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (14)..(14)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being 5' methylcytosine, q3 being F and the 
       other substituents being hydrogen

<220>
<221>  misc_feature
<222>  (15)..(15)
<223>  tricyclic nucleoside according to fomula I with T1 and T2 being 
       phosphorothioate, Bx being thymine, q3 being F and the other 
       substituents being hydrogen

<400>  21
aacctcggct tacct                                                        15


