               SEQUENCE LISTING

<110> Boehringer Ingelheim International GmbH

<120> Novel Intron Sequences

<130> P01-2884/WO/1

<160> 64

<170> BiSSAP 1.2

<210> 1
<211> 360
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..360
<223> /organism="artificial sequences"
      /note="intron sequence derivative derived from genomic region of
      human kappa light chain and further modified"
      /mol_type="unassigned DNA"

<400> 1
gtaagtgcac tttcctaata gatctaattc taaactctga gggggtcgga tgacgtggcc      60

attctttgcc taaagcattg agtttactgc aaggtcagaa aagcatgcaa agccctcaga     120

atggctgcaa agagctccaa caaaacaatt tagaacttta ttaaggaata gggggaagct     180

aggaagaaac tcaaaacatc aagattttaa atacgcttct tggtctcctt gctataatta     240

tctgggataa gcatgctgtt ttctgtctgt ccctaacatg ccctgtgatt atccgcaaac     300

aacacaccca agggcagaac tttgttatac taacaccatc ctgtttgctt ctttcctcag     360


<210> 2
<211> 304
<212> DNA
<213> Cricetulus griseus

<220> 
<221> source
<222> 1..304
<223> /organism="Cricetulus griseus"
      /note="intron sequence derived from genomic region of hamster dih
      ydrofolate reductase"
      /mol_type="unassigned DNA"

<400> 2
gtactggctg gattgggtta gggaaaccga ggcggttcgc tgaatcgggt cgagcacttg     60

gcggagacgc gcgggccaac tacttaggga cagtcatgag gggtaggccc gccggctgct    120

gcccttgccc atgcccgcgg tgatccccat gctgtgccag cctttgccca gaggcgctct    180

agctgggagc aaagtccggt cactgggcag caccaccccc cggacttgca tgggtagccg    240

ctgagatgga gcctgagcac acgtgacagg gtccctgtta acgcagtgtt tctctaactt    300

tcag                                                                 304


<210> 3
<211> 308
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..308
<223> /organism="artificial sequences"
      /note="intron sequence derived from genomic region of hamster dih
      ydrofolate reductase and further modified"
      /mol_type="unassigned DNA"

<400> 3
gtaagtgctg gattgggtta gatctggaaa ccgaggcggt tcgctgaatc gggtcgagca     60

cttggcggag acgcgcgggc caactactta gggacagtca tgaggggtag gcccgccggc    120

tgctgccctt gcccatgccc gcggtgatcc ccatgctgtg ccagcctttg cccagaggcg    180

ctctagctgg gagcaaagtc cggtcactgg gcagcaccac cccccggact tgcatgggta    240

gccgctgaga tggagcctga gcacacgtga cagggtccct gttaacgcag tgtttctctc    300

cctttcag                                                             308


<210> 4
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 4
Thr Val Ser Ser Ala Ser Thr Lys 
1               5               

<210> 5
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 5
accgtctctt caggtgagt                                                 19


<210> 6
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 6
ccacctctct tgcagcctcc accaag                                         26


<210> 7
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 7
Thr Val Ser Ala Ala Ser Thr Lys 
1               5               

<210> 8
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 8
acagtgtctg caggtgagt                                                 19


<210> 9
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 9
accgtctctg caggtgagt                                                 19


<210> 10
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 10
Asp Lys Arg Val Glu Pro Lys Ser 
1               5               

<210> 11
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 11
gacaagagag ttggtgaga                                                 19


<210> 12
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 12
atcttctctc tgcagagccc aaatct                                         26


<210> 13
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 13
Asp Lys Lys Ala Glu Pro Lys Ser 
1               5               

<210> 14
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 14
gacaagaaag caggtgaga                                                 19


<210> 15
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 15
Asp Lys Thr Val Ala Ser Thr Lys 
1               5               

<210> 16
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 16
gacaagacag ttggtgaga                                                 19


<210> 17
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 17
Asp Lys Arg Val Glu Ser Lys Tyr 
1               5               

<210> 18
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 18
atcttctctc tgcagagtcc aaatat                                         26


<210> 19
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 19
Asp Lys Lys Val Glu Pro Lys Ser 
1               5               

<210> 20
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 20
gacaagaaag ttggtgaga                                                 19


<210> 21
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 21
Pro Pro Cys Pro Ala Pro Glu Leu 
1               5               

<210> 22
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 22
ccaccgtgcc caggtaagc                                                 19


<210> 23
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 23
ccatctcttc ctcagcacct gaactc                                         26


<210> 24
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 24
Pro Pro Cys Pro Ala Pro Pro Val 
1               5               

<210> 25
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 25
ccatctcttc ctcagcacca cctgtg                                         26


<210> 26
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4

<400> 26
Pro Pro Cys Pro Ala Pro Glu Phe 
1               5               

<210> 27
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 27
ccaccatgcc caggtaagc                                                 19


<210> 28
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4"
      /mol_type="unassigned DNA"

<400> 28
ccatctcttc ctcagcacct gagttc                                         26


<210> 29
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4 (continued)

<400> 29
Ser Lys Ala Lys Gly Gln Pro Arg 
1               5               

<210> 30
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 30
tccaaagcca aaggtggga                                                 19


<210> 31
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 31
cctctgtccc tacagggcag ccccga                                         26


<210> 32
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4 (continued)

<400> 32
Ser Lys Thr Lys Gly Gln Pro Arg 
1               5               

<210> 33
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 33
tccaaaacca aaggtggga                                                 19


<210> 34
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4 (continued)

<400> 34
Leu Glu Ile Lys Arg Thr Val Ala 
1               5               

<210> 35
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 35
ctggagatca aacgtagtg                                                 19


<210> 36
<211> 26
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..26
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 36
tgcttctttc ctcaggaact gtggct                                         26


<210> 37
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 4 (continued)

<400> 37
Val Glu Ile Lys Arg Thr Val Ala 
1               5               

<210> 38
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 4 (continued)"
      /mol_type="unassigned DNA"

<400> 38
gtggagatca aacgtaagt                                                 19


<210> 39
<211> 7
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 7

<400> 39
Val Ala Thr Ala Thr Gly Val 
1               5           

<210> 40
<211> 10
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..10
<223> /organism="artificial sequences"
      /note="Figure 7"
      /mol_type="unassigned DNA"

<400> 40
gtggccacag                                                           10


<210> 41
<211> 11
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..11
<223> /organism="artificial sequences"
      /note="Figure 7"
      /mol_type="unassigned DNA"

<400> 41
ccaccggcgt g                                                         11


<210> 42
<211> 9
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 8

<400> 42
Gly Thr Ser Val Thr Val Ser Ser Ala 
1               5                   

<210> 43
<211> 16
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..16
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 43
ggtacctcag tcacag                                                    16


<210> 44
<211> 11
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..11
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 44
tgagctcagc c                                                         11


<210> 45
<211> 9
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 8

<400> 45
Gly Thr Thr Val Thr Val Ser Ala Ala 
1               5                   

<210> 46
<211> 16
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..16
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 46
ggtaccaccg tgacag                                                    16


<210> 47
<211> 11
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..11
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 47
tgtctgcagc c                                                         11


<210> 48
<211> 9
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 8

<400> 48
Gly Thr Leu Val Thr Val Ser Ser Ala 
1               5                   

<210> 49
<211> 16
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..16
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 49
ggtaccctgg tcacag                                                    16


<210> 50
<211> 9
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 8

<400> 50
Gly Thr Leu Val Ile Val Ser Ser Ala 
1               5                   

<210> 51
<211> 16
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..16
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 51
gttaccctgg tgatag                                                    16


<210> 52
<211> 11
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..11
<223> /organism="artificial sequences"
      /note="Figure 8"
      /mol_type="unassigned DNA"

<400> 52
tgtctgcagc t                                                         11


<210> 53
<211> 11
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 9

<400> 53
Gly Thr Glu Leu Glu Ile Lys Arg Thr Val Ala 
1               5                   10      

<210> 54
<211> 21
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..21
<223> /organism="artificial sequences"
      /note="Figure 9"
      /mol_type="unassigned DNA"

<400> 54
ggtaccgaac tggagatcaa g                                              21


<210> 55
<211> 12
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..12
<223> /organism="artificial sequences"
      /note="Figure 9"
      /mol_type="unassigned DNA"

<400> 55
cgtacggtgg ct                                                        12


<210> 56
<211> 11
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 9

<400> 56
Gly Thr Lys Leu Glu Ile Lys Arg Thr Val Ala 
1               5                   10      

<210> 57
<211> 21
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..21
<223> /organism="artificial sequences"
      /note="Figure 9"
      /mol_type="unassigned DNA"

<400> 57
ggtaccaagc tggagatcaa g                                              21


<210> 58
<211> 8
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 9

<400> 58
Gly Thr Lys Leu Thr Val Leu Gly 
1               5               

<210> 59
<211> 15
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..15
<223> /organism="artificial sequences"
      /note="Figure 9"
      /mol_type="unassigned DNA"

<400> 59
ttaaccgtcc taggt                                                     15


<210> 60
<211> 13
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 10

<400> 60
Leu Leu Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 
1               5                   10              

<210> 61
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 10"
      /mol_type="unassigned DNA"

<400> 61
ctgctgggcg ggccctcag                                                 19


<210> 62
<211> 20
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..20
<223> /organism="artificial sequences"
      /note="Figure 10"
      /mol_type="unassigned DNA"

<400> 62
tcttcctctt ccccccaaaa                                                20


<210> 63
<211> 13
<212> PRT
<213> artificial sequences

<220> 
<223> Figure 10

<400> 63
Ala Ala Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys 
1               5                   10              

<210> 64
<211> 19
<212> DNA
<213> artificial sequences

<220> 
<221> source
<222> 1..19
<223> /organism="artificial sequences"
      /note="Figure 10"
      /mol_type="unassigned DNA"

<400> 64
gccgctggcg ggccctcag                                                 19


