                         SEQUENCE LISTING

<110> Arrowhead Research Corporation
      Chin, Daniel
      Deckert, Jochen
      Hossbach, Markus
      John, Matthias

<120> Compositions and Methods for Inhibiting Gene Expression of
      Hepatitis B Virus

<130> 27394 WO1

<160> 648

<170>  PatentIn version 3.5

<210> 1
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 1
caagguaugu ugcccguuu 19


<210> 2
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 2
cuguaggcau aaauuggua 19


<210> 3
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 3
ucugcggcgu uuuaucaua 19


<210> 4
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 4
accucugccu aaucaucuc 19


<210> 5
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 5
uuuacuagug ccauuugua 19


<210> 6
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 6
accucugccu aaucaucua 19


<210> 7
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 7
cuguaggcau aaauugguc 19


<210> 8
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 8
ugucugcggc guuuuauca 19


<210> 9
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 9
uacuagugcc auuuguuca 19


<210> 10
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 10
caacuuuuuc accucugca 19


<210> 11
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 11
ccauuuguuc agugguucg 19


<210> 12
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 12
ccaaguguuu gcugacgca 19


<210> 13
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 13
ccauuuguuc agugguuca 19


<210> 14
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 14
uuuacuagug ccauuuguu 19


<210> 15
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 15
caccucugcc uaaucauca 19


<210> 16
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 16
cuggcucagu uuacuagug 19


<210> 17
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 17
caagguaugu ugcccguua 19


<210> 18
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 18
cuggcucagu uuacuagua 19


<210> 19
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 19
gaggcuguag gcauaaauu 19


<210> 20
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 20
caguuuacua gugccauuu 19


<210> 21
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 21
agguauguug cccguuugu 19


<210> 22
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 22
uauguugccc guuugucca 19


<210> 23
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 23
gaggcuguag gcauaaaua 19


<210> 24
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 24
gucugcggcg uuuuaucau 19


<210> 25
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 25
caacuuuuuc accucugcc 19


<210> 26
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 26
ccgugugcac uucgcuuca 19


<210> 27
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 27
ucaagguaug uugcccgua 19


<210> 28
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 28
caguuuacua gugccauua 19


<210> 29
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 29
ugguggacuu cucucaauu 19


<210> 30
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 30
agguauguug cccguuuga 19


<210> 31
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 31
cugcucgugu uacaggcgg 19


<210> 32
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 32
uauguugccc guuuguccu 19


<210> 33
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 33
ucaagguaug uugcccguu 19


<210> 34
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 34
ucuuaucaac acuuccgga 19


<210> 35
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 35
caccucugcc uaaucaucu 19


<210> 36
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 36
auaagaggac ucuuggacu 19


<210> 37
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 37
gucugcggcg uuuuaucaa 19


<210> 38
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 38
ggcgcugaau cccgcggac 19


<210> 39
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 39
cgcgucgcag aagaucuca 19


<210> 40
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 40
aaugucaacg accgaccuu 19


<210> 41
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 41
gcucaguuua cuagugcca 19


<210> 42
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 42
ugguggacuu cucucaaua 19


<210> 43
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 43
aucgccgcgu cgcagaaga 19


<210> 44
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 44
gccauuuguu cagugguuc 19


<210> 45
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 45
cgauccauac ugcggaacu 19


<210> 46
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 46
ucaccucugc cuaaucauc 19


<210> 47
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 47
guggacuucu cucaauuuu 19


<210> 48
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 48
gggucaccau auucuuggg 19


<210> 49
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 49
gccgcgucgc agaagaucu 19


<210> 50
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 50
ucaaucgccg cgucgcaga 19


<210> 51
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 51
uggauguguc ugcggcguu 19


<210> 52
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 52
uacuguucaa gccuccaag 19


<210> 53
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 53
guuuacuagu gccauuugu 19


<210> 54
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 54
acuagugcca uuuguucag 19


<210> 55
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 55
ccgcgucgca gaagaucuc 19


<210> 56
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 56
uaucuuauca acacuuccg 19


<210> 57
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 57
ggccaaaauu cgcaguccc 19


<210> 58
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 58
uucaccucug ccuaaucau 19


<210> 59
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 59
cucaguuuac uagugccau 19


<210> 60
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 60
uguugcccgu uuguccucu 19


<210> 61
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 61
uagugccauu uguucagug 19


<210> 62
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 62
aggcuguagg cauaaauug 19


<210> 63
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 63
augugucugc ggcguuuua 19


<210> 64
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 64
acuucgcuuc accucugca 19


<210> 65
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 65
cgugugcacu ucgcuucac 19


<210> 66
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 66
gugguggacu ucucucaau 19


<210> 67
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 67
ugugucugcg gcguuuuau 19


<210> 68
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 68
aagguauguu gcccguuug 19


<210> 69
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 69
ucaacgaccg accuugagg 19


<210> 70
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 70
cauaagagga cucuuggac 19


<210> 71
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 71
gucaacgacc gaccuugag 19


<210> 72
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 72
auauucuugg gaacaagag 19


<210> 73
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 73
ugcucguguu acaggcggg 19


<210> 74
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 74
caaucgccgc gucgcagaa 19


<210> 75
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 75
acuguucaag ccuccaagc 19


<210> 76
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 76
cgccgcgucg cagaagauc 19


<210> 77
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 77
cauuuguuca gugguucgu 19


<210> 78
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 78
cgcugaaucc cgcggacga 19


<210> 79
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 79
ugggucacca uauucuugg 19


<210> 80
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 80
uccucugccg auccauacu 19


<210> 81
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 81
augucaacga ccgaccuug 19


<210> 82
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 82
ccucugccua aucaucuca 19


<210> 83
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 83
accgugugca cuucgcuuc 19


<210> 84
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 84
ugccgaucca uacugcgga 19


<210> 85
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 85
cagagucuag acucguggu 19


<210> 86
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 86
cuguucaagc cuccaagcu 19


<210> 87
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 87
ggaggcugua ggcauaaau 19


<210> 88
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 88
aggaggcugu aggcauaaa 19


<210> 89
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 89
gguggacuuc ucucaauuu 19


<210> 90
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 90
gcaacuuuuu caccucugc 19


<210> 91
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 91
cugcucgugu uacaggcga 19


<210> 92
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 92
cuagugccau uuguucagu 19


<210> 93
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 93
cugccgaucc auacugcgg 19


<210> 94
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 94
gugugcacuu cgcuucacc 19


<210> 95
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 95
gcucguguua caggcgggc 19


<210> 96
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 96
ccuaucuuau caacacuuc 19


<210> 97
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 97
ucucaaucgc cgcgucgca 19


<210> 98
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 98
gcccgucugu gccuucuca 19


<210> 99
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 99
cuaucuuauc aacacuucc 19


<210> 100
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 100
auguugcccg uuuguccuc 19


<210> 101
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 101
guauguugcc cguuugucc 19


<210> 102
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 102
cuucgcuuca ccucugcac 19


<210> 103
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 103
ugugcacuuc gcuucaccu 19


<210> 104
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 104
gccaaaauuc gcagucccg 19


<210> 105
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 105
ccugcucgug uuacaggcg 19


<210> 106
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 106
uggagugugg auucgcacu 19


<210> 107
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 107
aacgaccgac cuugaggca 19


<210> 108
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 108
acagagucua gacucgugg 19


<210> 109
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 109
aaucgccgcg ucgcagaag 19


<210> 110
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 110
gguauguugc ccguuuguc 19


<210> 111
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 111
gccgauccau acugcggaa 19


<210> 112
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 112
gcccuaucuu aucaacacu 19


<210> 113
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 113
aguuuacuag ugccauuug 19


<210> 114
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 114
ugucaacgac cgaccuuga 19


<210> 115
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 115
acuucucuca auuuucuag 19


<210> 116
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 116
gcgcgggacg uccuuuguc 19


<210> 117
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 117
ucuagacucg ugguggacu 19


<210> 118
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 118
gauccauacu gcggaacuc 19


<210> 119
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 119
cucugccgau ccauacugc 19


<210> 120
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 120
ucugccgauc cauacugcg 19


<210> 121
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 121
ccucugccga uccauacug 19


<210> 122
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 122
gcaccucucu uuacgcggu 19


<210> 123
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 123
aagaacuccc ucgccucgc 19


<210> 124
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 124
gaacucccuc gccucgcag 19


<210> 125
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 125
ucucucaauu uucuagggc 19


<210> 126
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 126
gggcgcaccu cucuuuacg 19


<210> 127
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 127
ccgauccaua cugcggaac 19


<210> 128
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 128
aacucccucg ccucgcaga 19


<210> 129
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 129
cuccucugcc gauccauac 19


<210> 130
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 130
ggagugugga uucgcacuc 19


<210> 131
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 131
cgggcgcacc ucucuuuac 19


<210> 132
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 132
gucucaaucg ccgcgucgc 19


<210> 133
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 133
auccauacug cggaacucc 19


<210> 134
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 134
cgcaccucuc uuuacgcgg 19


<210> 135
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 135
caacgaccga ccuugaggc 19


<210> 136
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 136
ccauacugcg gaacuccua 19


<210> 137
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 137
ugaaucccgc ggacgaccc 19


<210> 138
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 138
agaacucccu cgccucgca 19


<210> 139
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 139
ggcgcaccuc ucuuuacgc 19


<210> 140
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 140
gcgcaccucu cuuuacgcg 19


<210> 141
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 141
gcugaauccc gcggacgac 19


<210> 142
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 142
cacuucgcuu caccucugc 19


<210> 143
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 143
cucaaucgcc gcgucgcag 19


<210> 144
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 144
ucccgucggc gcugaaucc 19


<210> 145
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 145
cugaaucccg cggacgacc 19


<210> 146
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 146
agagucuaga cucguggug 19


<210> 147
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 147
uccauacugc ggaacuccu 19


<210> 148
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 148
gcgcugaauc ccgcggacg 19


<210> 149
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 149
aguguggauu cgcacuccu 19


<210> 150
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 150
cccugcucgu guuacaggc 19


<210> 151
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 151
gaaucccgcg gacgacccg 19


<210> 152
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 152
aagcugugcc uuggguggc 19


<210> 153
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 153
gcccugcucg uguuacagg 19


<210> 154
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 154
gucccgucgg cgcugaauc 19


<210> 155
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 155
aucuuaucaa cacuuccgg 19


<210> 156
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 156
cuuaucaaca cuuccggaa 19


<210> 157
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 157
aaacgggcaa cauaccuug 19


<210> 158
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 158
taccaauuua ugccuacag 19


<210> 159
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 159
uaugauaaaa cgccgcaga 19


<210> 160
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 160
taugauaaaa cgccgcaga 19


<210> 161
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 161
gagaugauua ggcagaggu 19


<210> 162
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 162
tacaaauggc acuaguaaa 19


<210> 163
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 163
tagaugauua ggcagaggu 19


<210> 164
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 164
gaccaauuua ugccuacag 19


<210> 165
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 165
ugauaaaacg ccgcagaca 19


<210> 166
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 166
tgauaaaacg ccgcagaca 19


<210> 167
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 167
ugaacaaaug gcacuagua 19


<210> 168
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 168
tgaacaaaug gcacuagua 19


<210> 169
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 169
tgcagaggug aaaaaguug 19


<210> 170
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 170
cgaaccacug aacaaaugg 19


<210> 171
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 171
ugcgucagca aacacuugg 19


<210> 172
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 172
tgcgucagca aacacuugg 19


<210> 173
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 173
tgaaccacug aacaaaugg 19


<210> 174
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 174
aacaaauggc acuaguaaa 19


<210> 175
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 175
tgaugauuag gcagaggug 19


<210> 176
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 176
cacuaguaaa cugagccag 19


<210> 177
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 177
taacgggcaa cauaccuug 19


<210> 178
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 178
tacuaguaaa cugagccag 19


<210> 179
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 179
aauuuaugcc uacagccuc 19


<210> 180
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 180
aaauggcacu aguaaacug 19


<210> 181
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 181
acaaacgggc aacauaccu 19


<210> 182
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 182
uggacaaacg ggcaacaua 19


<210> 183
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 183
tauuuaugcc uacagccuc 19


<210> 184
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 184
augauaaaac gccgcagac 19


<210> 185
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 185
ggcagaggug aaaaaguug 19


<210> 186
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 186
ugaagcgaag ugcacacgg 19


<210> 187
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 187
tgaagcgaag ugcacacgg 19


<210> 188
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 188
tacgggcaac auaccuuga 19


<210> 189
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 189
taauggcacu aguaaacug 19


<210> 190
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 190
aauugagaga aguccacca 19


<210> 191
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 191
tcaaacgggc aacauaccu 19


<210> 192
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 192
ccgccuguaa cacgagcag 19


<210> 193
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 193
aggacaaacg ggcaacaua 19


<210> 194
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 194
aacgggcaac auaccuuga 19


<210> 195
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 195
uccggaagug uugauaaga 19


<210> 196
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 196
tccggaagug uugauaaga 19


<210> 197
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 197
agaugauuag gcagaggug 19


<210> 198
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 198
aguccaagag uccucuuau 19


<210> 199
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 199
tugauaaaac gccgcagac 19


<210> 200
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 200
guccgcggga uucagcgcc 19


<210> 201
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 201
ugagaucuuc ugcgacgcg 19


<210> 202
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 202
aaggucgguc guugacauu 19


<210> 203
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 203
uggcacuagu aaacugagc 19


<210> 204
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 204
tauugagaga aguccacca 19


<210> 205
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 205
ucuucugcga cgcggcgau 19


<210> 206
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 206
gaaccacuga acaaauggc 19


<210> 207
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 207
aguuccgcag uauggaucg 19


<210> 208
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 208
gaugauuagg cagagguga 19


<210> 209
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 209
aaaauugaga gaaguccac 19


<210> 210
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 210
cccaagaaua uggugaccc 19


<210> 211
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 211
agaucuucug cgacgcggc 19


<210> 212
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 212
ucugcgacgc ggcgauuga 19


<210> 213
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 213
aacgccgcag acacaucca 19


<210> 214
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 214
cuuggaggcu ugaacagua 19


<210> 215
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 215
acaaauggca cuaguaaac 19


<210> 216
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 216
cugaacaaau ggcacuagu 19


<210> 217
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 217
gagaucuucu gcgacgcgg 19


<210> 218
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 218
cggaaguguu gauaagaua 19


<210> 219
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 219
gggacugcga auuuuggcc 19


<210> 220
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 220
augauuaggc agaggugaa 19


<210> 221
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 221
auggcacuag uaaacugag 19


<210> 222
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 222
agaggacaaa cgggcaaca 19


<210> 223
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 223
cacugaacaa auggcacua 19


<210> 224
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 224
caauuuaugc cuacagccu 19


<210> 225
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 225
uaaaacgccg cagacacau 19


<210> 226
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 226
taaaacgccg cagacacau 19


<210> 227
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 227
ugcagaggug aagcgaagu 19


<210> 228
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 228
gugaagcgaa gugcacacg 19


<210> 229
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 229
auugagagaa guccaccac 19


<210> 230
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 230
auaaaacgcc gcagacaca 19


<210> 231
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 231
caaacgggca acauaccuu 19


<210> 232
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 232
ccucaagguc ggucguuga 19


<210> 233
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 233
guccaagagu ccucuuaug 19


<210> 234
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 234
cucaaggucg gucguugac 19


<210> 235
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 235
cucuuguucc caagaauau 19


<210> 236
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 236
cccgccugua acacgagca 19


<210> 237
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 237
uucugcgacg cggcgauug 19


<210> 238
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 238
gcuuggaggc uugaacagu 19


<210> 239
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 239
gaucuucugc gacgcggcg 19


<210> 240
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 240
acgaaccacu gaacaaaug 19


<210> 241
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 241
ucguccgcgg gauucagcg 19


<210> 242
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 242
ccaagaauau ggugaccca 19


<210> 243
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 243
aguauggauc ggcagagga 19


<210> 244
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 244
caaggucggu cguugacau 19


<210> 245
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 245
ugagaugauu aggcagagg 19


<210> 246
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 246
gaagcgaagu gcacacggu 19


<210> 247
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 247
uccgcaguau ggaucggca 19


<210> 248
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 248
accacgaguc uagacucug 19


<210> 249
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 249
agcuuggagg cuugaacag 19


<210> 250
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 250
auuuaugccu acagccucc 19


<210> 251
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 251
uuuaugccua cagccuccu 19


<210> 252
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 252
aaauugagag aaguccacc 19


<210> 253
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 253
gcagagguga aaaaguugc 19


<210> 254
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 254
tcgccuguaa cacgagcag 19


<210> 255
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 255
acugaacaaa uggcacuag 19


<210> 256
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 256
ccgcaguaug gaucggcag 19


<210> 257
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 257
ggugaagcga agugcacac 19


<210> 258
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 258
gcccgccugu aacacgagc 19


<210> 259
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 259
gaaguguuga uaagauagg 19


<210> 260
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 260
ugcgacgcgg cgauugaga 19


<210> 261
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 261
ugagaaggca cagacgggc 19


<210> 262
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 262
ggaaguguug auaagauag 19


<210> 263
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 263
gaggacaaac gggcaacau 19


<210> 264
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 264
ggacaaacgg gcaacauac 19


<210> 265
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 265
gugcagaggu gaagcgaag 19


<210> 266
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 266
aggugaagcg aagugcaca 19


<210> 267
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 267
cgggacugcg aauuuuggc 19


<210> 268
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 268
cgccuguaac acgagcagg 19


<210> 269
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 269
agugcgaauc cacacucca 19


<210> 270
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 270
ugccucaagg ucggucguu 19


<210> 271
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 271
ccacgagucu agacucugu 19


<210> 272
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 272
cuucugcgac gcggcgauu 19


<210> 273
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 273
gacaaacggg caacauacc 19


<210> 274
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 274
uuccgcagua uggaucggc 19


<210> 275
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 275
aguguugaua agauagggc 19


<210> 276
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 276
caaauggcac uaguaaacu 19


<210> 277
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 277
ucaaggucgg ucguugaca 19


<210> 278
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 278
cuagaaaauu gagagaagu 19


<210> 279
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 279
gacaaaggac gucccgcgc 19


<210> 280
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 280
aguccaccac gagucuaga 19


<210> 281
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 281
gaguuccgca guauggauc 19


<210> 282
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 282
gcaguaugga ucggcagag 19


<210> 283
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 283
cgcaguaugg aucggcaga 19


<210> 284
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 284
caguauggau cggcagagg 19


<210> 285
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 285
accgcguaaa gagaggugc 19


<210> 286
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 286
gcgaggcgag ggaguucuu 19


<210> 287
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 287
cugcgaggcg agggaguuc 19


<210> 288
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 288
gcccuagaaa auugagaga 19


<210> 289
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 289
cguaaagaga ggugcgccc 19


<210> 290
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 290
guuccgcagu auggaucgg 19


<210> 291
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 291
ucugcgaggc gagggaguu 19


<210> 292
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 292
guauggaucg gcagaggag 19


<210> 293
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 293
gagugcgaau ccacacucc 19


<210> 294
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 294
guaaagagag gugcgcccg 19


<210> 295
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 295
gcgacgcggc gauugagac 19


<210> 296
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 296
ggaguuccgc aguauggau 19


<210> 297
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 297
ccgcguaaag agaggugcg 19


<210> 298
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 298
gccucaaggu cggucguug 19


<210> 299
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 299
uaggaguucc gcaguaugg 19


<210> 300
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 300
gggucguccg cgggauuca 19


<210> 301
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 301
ugcgaggcga gggaguucu 19


<210> 302
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 302
gcguaaagag aggugcgcc 19


<210> 303
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 303
cgcguaaaga gaggugcgc 19


<210> 304
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 304
gucguccgcg ggauucagc 19


<210> 305
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 305
gcagagguga agcgaagug 19


<210> 306
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 306
cugcgacgcg gcgauugag 19


<210> 307
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 307
ggauucagcg ccgacggga 19


<210> 308
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 308
ggucguccgc gggauucag 19


<210> 309
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 309
caccacgagu cuagacucu 19


<210> 310
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 310
aggaguuccg caguaugga 19


<210> 311
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 311
cguccgcggg auucagcgc 19


<210> 312
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 312
aggagugcga auccacacu 19


<210> 313
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 313
gccuguaaca cgagcaggg 19


<210> 314
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 314
cgggucgucc gcgggauuc 19


<210> 315
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 315
gccacccaag gcacagcuu 19


<210> 316
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 316
ccuguaacac gagcagggc 19


<210> 317
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 317
gauucagcgc cgacgggac 19


<210> 318
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 318
ccggaagugu ugauaagau 19


<210> 319
<211> 19
<212> RNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<400> 319
uuccggaagu guugauaag 19


<210> 320
<211> 19
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 320
tuccggaagu guugauaag 19


<210> 321
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 8, 10, 11, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 7, 9, 12, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 321
caagguaugu ugcccguuut t 21


<210> 322
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 322
cuguaggcau aaauugguat  20


<210> 323
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 8, 10, 11, 12, 13, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 7, 9, 14, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 323
ucugcggcgu uuuaucauat t 21


<210> 324
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 324
ucugcggcgu uuuaucauat  20


<210> 325
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 7, 11, 12, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 325
accucugccu aaucaucuct t 21


<210> 326
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 326
uuuacuagug ccauuuguat  20


<210> 327
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 327
accucugccu aaucaucuat  20


<210> 328
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 8, 10, 14, 15, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 6, 7, 9, 11, 12, 13, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 328
cuguaggcau aaauugguct t 21


<210> 329
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 10, 12, 13, 14, 15, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 8, 9, 11, 16, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 329
ugucugcggc guuuuaucat t 21


<210> 330
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 330
ugucugcggc guuuuaucat  20


<210> 331
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 7, 9, 10, 12, 13, 14, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 8, 11, 15, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 331
uacuagugcc auuuguucat t 21


<210> 332
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 332
uacuagugcc auuuguucat  20


<210> 333
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 333
caacuuuuuc accucugcat  20


<210> 334
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 8, 9, 10, 13, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 7, 11, 12, 14, 15, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 334
ccauuuguuc agugguucgt t 21


<210> 335
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 8, 9, 10, 12, 13, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 7, 11, 14, 15, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 335
ccaaguguuu gcugacgcat t 21


<210> 336
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 336
ccaaguguuu gcugacgcat  20


<210> 337
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 337
ccauuuguuc agugguucat  20


<210> 338
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 9, 11, 12, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 8, 10, 13, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 338
uuuacuagug ccauuuguut t 21


<210> 339
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 339
caccucugcc uaaucaucat  20


<210> 340
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 10, 11, 12, 14, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 8, 9, 13, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 340
cuggcucagu uuacuagugt t 21


<210> 341
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 341
caagguaugu ugcccguuat  20


<210> 342
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 342
cuggcucagu uuacuaguat  20


<210> 343
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 8, 12, 14, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 7, 9, 10, 11, 13, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 343
gaggcuguag gcauaaauut t 21


<210> 344
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 8, 9, 12, 14, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 7, 10, 11, 13, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 344
caguuuacua gugccauuut t 21


<210> 345
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 8, 9, 11, 12, 13, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 7, 10, 14, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 345
agguauguug cccguuugut t 21


<210> 346
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 346
uauguugccc guuuguccat  20


<210> 347
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 347
gaggcuguag gcauaaauat  20


<210> 348
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 9, 11, 12, 13, 14, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 7, 8, 10, 15, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 348
gucugcggcg uuuuaucaut t 21


<210> 349
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 11, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 349
caacuuuuuc accucugcct t 21


<210> 350
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 8, 10, 11, 12, 13, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 7, 9, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 350
ccgugugcac uucgcuucat t 21


<210> 351
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 351
ccgugugcac uucgcuucat  20


<210> 352
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 352
ucaagguaug uugcccguat  20


<210> 353
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 353
caguuuacua gugccauuat  20


<210> 354
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 8, 9, 10, 11, 12, 13, 14, 15, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 6, 7, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 354
ugguggacuu cucucaauut t 21


<210> 355
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 355
agguauguug cccguuugat  20


<210> 356
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 8, 10, 11, 13, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 7, 9, 12, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 356
cugcucgugu uacaggcggt t 21


<210> 357
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 8, 9, 10, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 11, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 357
uauguugccc guuuguccut t 21


<210> 358
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 7, 9, 11, 12, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 6, 8, 10, 13, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 358
ucaagguaug uugcccguut t 21


<210> 359
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 10, 12, 13, 14, 15, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 8, 9, 11, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 359
ucuuaucaac acuuccggat t 21


<210> 360
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 360
ucuuaucaac acuuccggat  20


<210> 361
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 14, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 8, 12, 13, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 361
caccucugcc uaaucaucut t 21


<210> 362
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 10, 11, 12, 13, 14, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 6, 7, 8, 9, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 362
auaagaggac ucuuggacut t 21


<210> 363
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 363
gucugcggcg uuuuaucaat  20


<210> 364
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 10, 11, 12, 13, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 8, 9, 14, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 364
ggcgcugaau cccgcggact t 21


<210> 365
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 8, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 9, 10, 11, 12, 13, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 365
cgcgucgcag aagaucucat t 21


<210> 366
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 9, 12, 13, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 8, 10, 11, 14, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 366
aaugucaacg accgaccuut t 21


<210> 367
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 7, 8, 9, 11, 12, 15, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 10, 13, 14, 16, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 367
gcucaguuua cuagugccat t 21


<210> 368
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 368
ugguggacuu cucucaauat  20


<210> 369
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 8, 10, 11, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 9, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 369
aucgccgcgu cgcagaagat t 21


<210> 370
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 9, 10, 11, 14, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 8, 12, 13, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 370
gccauuuguu cagugguuct t 21


<210> 371
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 8, 10, 11, 13, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 7, 9, 12, 14, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 371
cgauccauac ugcggaacut t 21


<210> 372
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 10, 11, 12, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 9, 13, 14, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 372
ucaccucugc cuaaucauct t 21


<210> 373
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 7, 8, 9, 10, 11, 12, 13, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 14, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 373
guggacuucu cucaauuuut t 21


<210> 374
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 8, 10, 12, 13, 14, 15, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 9, 11, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 374
gggucaccau auucuugggt t 21


<210> 375
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 8, 10, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 9, 11, 12, 13, 14, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 375
gccgcgucgc agaagaucut t 21


<210> 376
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 8, 9, 11, 13, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 7, 10, 12, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 376
ucaaucgccg cgucgcagat t 21


<210> 377
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 7, 9, 10, 11, 13, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 8, 12, 14, 15, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 377
uggauguguc ugcggcguut t 21


<210> 378
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 12, 13, 14, 15, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 9, 10, 11, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 378
uacuguucaa gccuccaagt t 21


<210> 379
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 10, 12, 13, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 8, 9, 11, 14, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 379
guuuacuagu gccauuugut t 21


<210> 380
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 8, 9, 11, 12, 13, 15, 16, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 7, 10, 14, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 380
acuagugcca uuuguucagt t 21


<210> 381
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 9, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 8, 10, 11, 12, 13, 14, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 381
ccgcgucgca gaagaucuct t 21


<210> 382
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 12, 14, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 7, 10, 11, 13, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 382
uaucuuauca acacuuccgt t 21


<210> 383
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 9, 10, 11, 13, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 7, 8, 12, 14, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 383
ggccaaaauu cgcaguccct t 21


<210> 384
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 11, 12, 13, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 10, 14, 15, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 384
uucaccucug ccuaaucaut t 21


<210> 385
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 7, 8, 10, 11, 14, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 9, 12, 13, 15, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 385
cucaguuuac uagugccaut t 21


<210> 386
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 9, 13
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 386
uguugcccgu uuguccucut t 21


<210> 387
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 9, 10, 11, 13, 14, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 8, 12, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 387
uagugccauu uguucagugt t 21


<210> 388
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 11, 13, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 8, 9, 10, 12, 14, 15, 16, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 388
aggcuguagg cauaaauugt t 21


<210> 389
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 8, 10, 13, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 9, 11, 12, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 389
augugucugc ggcguuuuat t 21


<210> 390
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 390
augugucugc ggcguuuuat  20


<210> 391
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 12, 13, 14, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 11, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 391
acuucgcuuc accucugcat t 21


<210> 392
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 9, 10, 11, 12, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 8, 13, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 392
cgugugcacu ucgcuucact t 21


<210> 393
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 9, 10, 11, 12, 13, 14, 15, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 7, 8, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 393
gugguggacu ucucucaaut t 21


<210> 394
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 9, 12, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 8, 10, 11, 13, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 394
ugugucugcg gcguuuuaut t 21


<210> 395
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 7, 9, 10, 12, 13, 14, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 8, 11, 15, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 395
aagguauguu gcccguuugt t 21


<210> 396
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 8, 9, 12, 13, 14, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 7, 10, 11, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 396
ucaacgaccg accuugaggt t 21


<210> 397
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 11, 12, 13, 14, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 6, 7, 8, 9, 10, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 397
cauaagagga cucuuggact t 21


<210> 398
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 9, 10, 13, 14, 15, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 7, 8, 11, 12, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 398
gucaacgacc gaccuugagt t 21


<210> 399
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 399
auauucuugg gaacaagagt t 21


<210> 400
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 9, 10, 12, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 8, 11, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 400
ugcucguguu acaggcgggt t 21


<210> 401
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 8, 10, 12, 13, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 9, 11, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 401
caaucgccgc gucgcagaat t 21


<210> 402
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 11, 12, 13, 14, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 8, 9, 10, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 402
acuguucaag ccuccaagct t 21


<210> 403
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 8, 9, 11, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 7, 10, 12, 13, 14, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 403
cgccgcgucg cagaagauct t 21


<210> 404
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 12, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 10, 11, 13, 14, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 404
cauuuguuca gugguucgut t 21


<210> 405
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 8, 9, 10, 11, 13, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 7, 12, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 405
cgcugaaucc cgcggacgat t 21


<210> 406
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 8, 9, 11, 13, 14, 15, 16, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 7, 10, 12, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 406
ugggucacca uauucuuggt t 21


<210> 407
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 12, 13, 14, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 7, 10, 11, 15, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 407
uccucugccg auccauacut t 21


<210> 408
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 8, 11, 12, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 7, 9, 10, 13, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 408
augucaacga ccgaccuugt t 21


<210> 409
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 12, 13, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 10, 11, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 409
ccucugccua aucaucucat t 21


<210> 410
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 9, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 8, 10, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 410
accgugugca cuucgcuuct t 21


<210> 411
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 7, 8, 9, 11, 13, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 10, 12, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 411
ugccgaucca uacugcggat t 21


<210> 412
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 7, 8, 12, 13, 14, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 9, 10, 11, 15, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 412
cagagucuag acucguggut t 21


<210> 413
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 10, 11, 12, 13, 14, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 7, 8, 9, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 413
cuguucaagc cuccaagcut t 21


<210> 414
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 7, 9, 13, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 8, 10, 11, 12, 14, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 414
ggaggcugua ggcauaaaut t 21


<210> 415
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 7, 8, 10, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 6, 9, 11, 12, 13, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 415
aggaggcugu aggcauaaat t 21


<210> 416
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 7, 8, 9, 10, 11, 12, 13, 14, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 6, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 416
gguggacuuc ucucaauuut t 21


<210> 417
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 12, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 417
gcaacuuuuu caccucugct t 21


<210> 418
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 418
cugcucgugu uacaggcgat  20


<210> 419
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 7, 8, 10, 11, 12, 14, 15, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 9, 13, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 419
cuagugccau uuguucagut t 21


<210> 420
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 8, 9, 10, 12, 14, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 7, 11, 13, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 420
cugccgaucc auacugcggt t 21


<210> 421
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 8, 9, 10, 11, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 7, 12, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 421
gugugcacuu cgcuucacct t 21


<210> 422
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 8, 9, 11, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 7, 10, 12, 13, 14, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 422
gcucguguua caggcgggct t 21


<210> 423
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 10, 11, 14, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 9, 12, 13, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 423
ccuaucuuau caacacuuct t 21


<210> 424
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 7, 8, 10, 11, 13, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 9, 12, 14, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 424
ucucaaucgc cgcgucgcat t 21


<210> 425
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 10, 12, 13, 14, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 9, 11, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 425
gcccgucugu gccuucucat t 21


<210> 426
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 9, 10, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 8, 11, 12, 14
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 426
cuaucuuauc aacacuucct t 21


<210> 427
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 8, 9, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 10, 14
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 427
auguugcccg uuuguccuct t 21


<210> 428
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 9, 10, 11, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 8, 12, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 428
guauguugcc cguuugucct t 21


<210> 429
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 11, 12, 13, 14, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 10, 16, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 429
cuucgcuuca ccucugcact t 21


<210> 430
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 8, 9, 10, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 11, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 430
ugugcacuuc gcuucaccut t 21


<210> 431
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 8, 9, 10, 12, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 6, 7, 11, 13, 14, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 431
gccaaaauuc gcagucccgt t 21


<210> 432
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 9, 11, 12, 14, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 8, 10, 13, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 432
ccugcucgug uuacaggcgt t 21


<210> 433
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 8, 12, 13, 14, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 7, 9, 10, 11, 15, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 433
uggagugugg auucgcacut t 21


<210> 434
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 7, 10, 11, 12, 13, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 8, 9, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 434
aacgaccgac cuugaggcat t 21


<210> 435
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 7, 8, 9, 13, 14, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 6, 10, 11, 12, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 435
acagagucua gacucguggt t 21


<210> 436
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 9, 11, 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 8, 10, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 436
aaucgccgcg ucgcagaagt t 21


<210> 437
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 8, 10, 11, 12, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 9, 13, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 437
gguauguugc ccguuuguct t 21


<210> 438
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 7, 8, 10, 12, 13, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 9, 11, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 438
gccgauccau acugcggaat t 21


<210> 439
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 12, 13, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 11, 14, 15, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 439
gcccuaucuu aucaacacut t 21


<210> 440
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 9, 10, 12, 15, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 440
aguuuacuag ugccauuugt t 21


<210> 441
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 7, 10, 11, 14, 15, 16, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 6, 8, 9, 12, 13, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 441
ugucaacgac cgaccuugat t 21


<210> 442
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 10, 11, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 442
acuucucuca auuuucuagt t 21


<210> 443
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 9, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 6, 7, 8, 10, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 443
gcgcgggacg uccuuuguct t 21


<210> 444
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 7, 8, 9, 11, 14, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 6, 10, 12, 13, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 444
ucuagacucg ugguggacut t 21


<210> 445
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 9, 10, 12, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 8, 11, 13, 14, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 445
gauccauacu gcggaacuct t 21


<210> 446
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 10, 11, 12, 14, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 8, 9, 13, 15, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 446
cucugccgau ccauacugct t 21


<210> 447
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 9, 10, 11, 13, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 8, 12, 14, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 447
ucugccgauc cauacugcgt t 21


<210> 448
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 11, 12, 13, 15, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 9, 10, 14, 16, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 448
ccucugccga uccauacugt t 21


<210> 449
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 13, 15, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 449
gcaccucucu uuacgcggut t 21


<210> 450
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 13, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 450
aagaacuccc ucgccucgct t 21


<210> 451
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 11, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 451
gaacucccuc gccucgcagt t 21


<210> 452
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 9, 10, 11, 12, 13, 14, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 7, 8, 15, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 452
ucucucaauu uucuagggct t 21


<210> 453
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 7, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 453
gggcgcaccu cucuuuacgt t 21


<210> 454
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 9, 11, 12, 14, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 8, 10, 13, 15, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 454
ccgauccaua cugcggaact t 21


<210> 455
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 10, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 455
aacucccucg ccucgcagat t 21


<210> 456
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 13, 14, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 8, 11, 12, 16, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 456
cuccucugcc gauccauact t 21


<210> 457
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 7, 11, 12, 13, 15, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 8, 9, 10, 14, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 457
ggagugugga uucgcacuct t 21


<210> 458
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 6, 8, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 458
cgggcgcacc ucucuuuact t 21


<210> 459
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 8, 9, 11, 12, 14, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 7, 10, 13, 15, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 459
gucucaaucg ccgcgucgct t 21


<210> 460
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 8, 9, 11, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 7, 10, 12, 13, 14, 15
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 460
auccauacug cggaacucct t 21


<210> 461
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 14, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 461
cgcaccucuc uuuacgcggt t 21


<210> 462
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 7, 8, 11, 12, 13, 14, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 6, 9, 10, 15, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 462
caacgaccga ccuugaggct t 21


<210> 463
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 9, 14, 15, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 8, 10, 11, 12, 13, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 463
ccauacugcg gaacuccuat t 21


<210> 464
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 8, 10, 14, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 9, 11, 12, 13, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 464
ugaaucccgc ggacgaccct t 21


<210> 465
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 12, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 465
agaacucccu cgccucgcat t 21


<210> 466
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 16, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 466
ggcgcaccuc ucuuuacgct t 21


<210> 467
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 5, 15, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 467
gcgcaccucu cuuuacgcgt t 21


<210> 468
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 7, 8, 9, 10, 12, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 6, 11, 13, 14, 15, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 468
gcugaauccc gcggacgact t 21


<210> 469
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 7, 12, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 469
cacuucgcuu caccucugct t 21


<210> 470
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 6, 7, 9, 10, 12, 14, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 5, 8, 11, 13, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 470
cucaaucgcc gcgucgcagt t 21


<210> 471
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 10, 12, 13, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 8, 9, 11, 14, 15, 16
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 471
ucccgucggc gcugaaucct t 21


<210> 472
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 6, 7, 8, 9, 11, 15, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 5, 10, 12, 13, 14, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 472
cugaaucccg cggacgacct t 21


<210> 473
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 5, 6, 7, 11, 12, 13, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 4, 8, 9, 10, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 473
agagucuaga cucguggugt t 21


<210> 474
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 7, 8, 10, 15, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 9, 11, 12, 13, 14
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 474
uccauacugc ggaacuccut t 21


<210> 475
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 9, 10, 11, 12, 14, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 7, 8, 13, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 475
gcgcugaauc ccgcggacgt t 21


<210> 476
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 9, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 6, 7, 8, 12, 14
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 476
aguguggauu cgcacuccut t 21


<210> 477
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 10, 12, 13, 15, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 5, 9, 11, 14, 16, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 477
cccugcucgu guuacaggct t 21


<210> 478
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 9, 13, 16, 17, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 8, 10, 11, 12, 14, 15, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 478
gaaucccgcg gacgacccgt t 21


<210> 479
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 9, 10, 11, 12, 16, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 3, 6, 8, 13, 14, 15, 17, 18
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 479
aagcugugcc uuggguggct t 21


<210> 480
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 11, 13, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 10, 12, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 480
gcccugcucg uguuacaggt t 21


<210> 481
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 18, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 9, 10, 12, 15, 16, 17
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 481
gucccgucgg cgcugaauct t 21


<210> 482
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 6, 9, 10, 12, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 482
aucuuaucaa cacuuccggt t 21


<210> 483
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 9, 11, 12, 13, 14, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 4, 7, 8, 10, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 483
cuuaucaaca cuuccggaat t 21


<210> 484
<211> 20
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: sense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 1, 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 20
<223> /mod_base = "3'-3'-linked desoxythymidine"

<400> 484
cuuaucaaca cuuccggaat  20


<210> 485
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 8, 11, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 485
aaacgggcaa cauaccuugt t 21


<210> 486
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 486
taccaauuua ugccuacagt t 21


<210> 487
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 6, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 487
uaugauaaaa cgccgcagat t 21


<210> 488
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 488
taugauaaaa cgccgcagat t 21


<210> 489
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 9, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 489
gagaugauua ggcagaggut t 21


<210> 490
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 490
tacaaauggc acuaguaaat t 21


<210> 491
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 491
tagaugauua ggcagaggut t 21


<210> 492
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 9, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 10, 11, 12, 13, 14, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 492
gaccaauuua ugccuacagt t 21


<210> 493
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 14, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 493
ugauaaaacg ccgcagacat t 21


<210> 494
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 494
tgauaaaacg ccgcagacat t 21


<210> 495
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 12, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 13, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 495
ugaacaaaug gcacuaguat t 21


<210> 496
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 496
tgaacaaaug gcacuaguat t 21


<210> 497
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 497
tgcagaggug aaaaaguugt t 21


<210> 498
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 498
cgaaccacug aacaaauggt t 21


<210> 499
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 9, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 499
ugcgucagca aacacuuggt t 21


<210> 500
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 500
tgcgucagca aacacuuggt t 21


<210> 501
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 501
tgaaccacug aacaaauggt t 21


<210> 502
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 10, 13, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 502
aacaaauggc acuaguaaat t 21


<210> 503
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 503
tgaugauuag gcagaggugt t 21


<210> 504
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 4, 7, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 504
cacuaguaaa cugagccagt t 21


<210> 505
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 505
taacgggcaa cauaccuugt t 21


<210> 506
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 506
tacuaguaaa cugagccagt t 21


<210> 507
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 11, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 507
aauuuaugcc uacagccuct t 21


<210> 508
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 10, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 508
aaauggcacu aguaaacugt t 21


<210> 509
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 10, 13, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 509
acaaacgggc aacauaccut t 21


<210> 510
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 510
tggacaaacg ggcaacauat t 21


<210> 511
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 511
tauuuaugcc uacagccuct t 21


<210> 512
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 512
augauaaaac gccgcagact t 21


<210> 513
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 513
ggcagaggug aaaaaguugt t 21


<210> 514
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 13, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 514
ugaagcgaag ugcacacggt t 21


<210> 515
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 515
tgaagcgaag ugcacacggt t 21


<210> 516
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 516
tacgggcaac auaccuugat t 21


<210> 517
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 517
taauggcacu aguaaacugt t 21


<210> 518
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 518
aauugagaga aguccaccat t 21


<210> 519
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 519
tcaaacgggc aacauaccut t 21


<210> 520
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 8, 11, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 520
ccgccuguaa cacgagcagt t 21


<210> 521
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 13, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 14, 15, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 521
aggacaaacg ggcaacauat t 21


<210> 522
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 10, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 522
aacgggcaac auaccuugat t 21


<210> 523
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 523
uccggaagug uugauaagat t 21


<210> 524
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 524
tccggaagug uugauaagat t 21


<210> 525
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 8, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 525
agaugauuag gcagaggugt t 21


<210> 526
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 526
aguccaagag uccucuuaut t 21


<210> 527
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 527
tugauaaaac gccgcagact t 21


<210> 528
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 528
guccgcggga uucagcgcct t 21


<210> 529
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 529
ugagaucuuc ugcgacgcgt t 21


<210> 530
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 530
aaggucgguc guugacauut t 21


<210> 531
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 7, 10
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 531
uggcacuagu aaacugagct t 21


<210> 532
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 532
tauugagaga aguccaccat t 21


<210> 533
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 533
ucuucugcga cgcggcgaut t 21


<210> 534
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 534
gaaccacuga acaaauggct t 21


<210> 535
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 8, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 535
aguuccgcag uauggaucgt t 21


<210> 536
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 536
gaugauuagg cagaggugat t 21


<210> 537
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 537
aaaauugaga gaaguccact t 21


<210> 538
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 9
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 538
cccaagaaua uggugaccct t 21


<210> 539
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 539
agaucuucug cgacgcggct t 21


<210> 540
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 540
ucugcgacgc ggcgauugat t 21


<210> 541
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 8, 12, 14, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 9, 10, 11, 13, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 541
aacgccgcag acacauccat t 21


<210> 542
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 542
cuuggaggcu ugaacaguat t 21


<210> 543
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 9, 12, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 10, 11, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 543
acaaauggca cuaguaaact t 21


<210> 544
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 13, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 544
cugaacaaau ggcacuagut t 21


<210> 545
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 545
gagaucuucu gcgacgcggt t 21


<210> 546
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 13, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 546
cggaaguguu gauaagauat t 21


<210> 547
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 547
gggacugcga auuuuggcct t 21


<210> 548
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 10
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 548
augauuaggc agaggugaat t 21


<210> 549
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 8, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 549
auggcacuag uaaacugagt t 21


<210> 550
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 550
agaggacaaa cgggcaacat t 21


<210> 551
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 8, 15, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 551
cacugaacaa auggcacuat t 21


<210> 552
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 6, 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 7, 8, 9, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 552
caauuuaugc cuacagccut t 21


<210> 553
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 11, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 553
uaaaacgccg cagacacaut t 21


<210> 554
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 554
taaaacgccg cagacacaut t 21


<210> 555
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 555
ugcagaggug aagcgaagut t 21


<210> 556
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 556
gugaagcgaa gugcacacgt t 21


<210> 557
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 14, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 557
auugagagaa guccaccact t 21


<210> 558
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 12, 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 558
auaaaacgcc gcagacacat t 21


<210> 559
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 9, 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 8, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 559
caaacgggca acauaccuut t 21


<210> 560
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 560
ccucaagguc ggucguugat t 21


<210> 561
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 561
guccaagagu ccucuuaugt t 21


<210> 562
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 562
cucaaggucg gucguugact t 21


<210> 563
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 11, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 563
cucuuguucc caagaauaut t 21


<210> 564
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 9, 12, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 10, 11, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 564
cccgccugua acacgagcat t 21


<210> 565
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 565
uucugcgacg cggcgauugt t 21


<210> 566
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 566
gcuuggaggc uugaacagut t 21


<210> 567
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 567
gaucuucugc gacgcggcgt t 21


<210> 568
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 568
acgaaccacu gaacaaaugt t 21


<210> 569
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 569
ucguccgcgg gauucagcgt t 21


<210> 570
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 8, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 570
ccaagaauau ggugacccat t 21


<210> 571
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 571
aguauggauc ggcagaggat t 21


<210> 572
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 572
caaggucggu cguugacaut t 21


<210> 573
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 10, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 573
ugagaugauu aggcagaggt t 21


<210> 574
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 574
gaagcgaagu gcacacggut t 21


<210> 575
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 8, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 575
uccgcaguau ggaucggcat t 21


<210> 576
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 576
accacgaguc uagacucugt t 21


<210> 577
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 577
agcuuggagg cuugaacagt t 21


<210> 578
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 10, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 578
auuuaugccu acagccucct t 21


<210> 579
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 9, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 579
uuuaugccua cagccuccut t 21


<210> 580
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 580
aaauugagag aaguccacct t 21


<210> 581
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 581
gcagagguga aaaaguugct t 21


<210> 582
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 582
tcgccuguaa cacgagcagt t 21


<210> 583
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 14, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 583
acugaacaaa uggcacuagt t 21


<210> 584
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 7, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 584
ccgcaguaug gaucggcagt t 21


<210> 585
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 585
ggugaagcga agugcacact t 21


<210> 586
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 10, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 586
gcccgccugu aacacgagct t 21


<210> 587
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 11, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 587
gaaguguuga uaagauaggt t 21


<210> 588
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 588
ugcgacgcgg cgauugagat t 21


<210> 589
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 9, 11
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 10, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 589
ugagaaggca cagacgggct t 21


<210> 590
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 12, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 590
ggaaguguug auaagauagt t 21


<210> 591
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 14, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 591
gaggacaaac gggcaacaut t 21


<210> 592
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4, 12, 15, 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 13, 14, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 592
ggacaaacgg gcaacauact t 21


<210> 593
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 593
gugcagaggu gaagcgaagt t 21


<210> 594
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 594
aggugaagcg aagugcacat t 21


<210> 595
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 595
cgggacugcg aauuuuggct t 21


<210> 596
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 10, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 596
cgccuguaac acgagcaggt t 21


<210> 597
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 11, 13, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 597
agugcgaauc cacacuccat t 21


<210> 598
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 598
ugccucaagg ucggucguut t 21


<210> 599
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 10
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 599
ccacgagucu agacucugut t 21


<210> 600
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 600
cuucugcgac gcggcgauut t 21


<210> 601
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 11, 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 12, 13, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 601
gacaaacggg caacauacct t 21


<210> 602
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 9
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 602
uuccgcagua uggaucggct t 21


<210> 603
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 9, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 603
aguguugaua agauagggct t 21


<210> 604
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 8, 11, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 604
caaauggcac uaguaaacut t 21


<210> 605
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 605
ucaaggucgg ucguugacat t 21


<210> 606
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 606
cuagaaaauu gagagaagut t 21


<210> 607
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 607
gacaaaggac gucccgcgct t 21


<210> 608
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 8, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 608
aguccaccac gagucuagat t 21


<210> 609
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 9, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 10, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 609
gaguuccgca guauggauct t 21


<210> 610
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 5, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 610
gcaguaugga ucggcagagt t 21


<210> 611
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 6, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 611
cgcaguaugg aucggcagat t 21


<210> 612
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 4, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 612
caguauggau cggcagaggt t 21


<210> 613
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 613
accgcguaaa gagaggugct t 21


<210> 614
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 614
gcgaggcgag ggaguucuut t 21


<210> 615
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 615
cugcgaggcg agggaguuct t 21


<210> 616
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 616
gcccuagaaa auugagagat t 21


<210> 617
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 617
cguaaagaga ggugcgccct t 21


<210> 618
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 7, 10
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 618
guuccgcagu auggaucggt t 21


<210> 619
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 619
ucugcgaggc gagggaguut t 21


<210> 620
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 620
guauggaucg gcagaggagt t 21


<210> 621
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 621
gagugcgaau ccacacucct t 21


<210> 622
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 622
guaaagagag gugcgcccgt t 21


<210> 623
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 623
gcgacgcggc gauugagact t 21


<210> 624
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 10, 13
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 624
ggaguuccgc aguauggaut t 21


<210> 625
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 625
ccgcguaaag agaggugcgt t 21


<210> 626
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 626
gccucaaggu cggucguugt t 21


<210> 627
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 12, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 627
uaggaguucc gcaguauggt t 21


<210> 628
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 18
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 628
gggucguccg cgggauucat t 21


<210> 629
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 629
ugcgaggcga gggaguucut t 21


<210> 630
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 4
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 630
gcguaaagag aggugcgcct t 21


<210> 631
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 631
cgcguaaaga gaggugcgct t 21


<210> 632
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 632
gucguccgcg ggauucagct t 21


<210> 633
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 2
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 633
gcagagguga agcgaagugt t 21


<210> 634
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 634
cugcgacgcg gcgauugagt t 21


<210> 635
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 635
ggauucagcg ccgacgggat t 21


<210> 636
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 17
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 636
ggucguccgc gggauucagt t 21


<210> 637
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 1, 4, 12
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 2, 3, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 637
caccacgagu cuagacucut t 21


<210> 638
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 11, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 638
aggaguuccg caguauggat t 21


<210> 639
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 639
cguccgcggg auucagcgct t 21


<210> 640
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 14, 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 640
aggagugcga auccacacut t 21


<210> 641
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 6, 9, 15
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 7, 8, 10, 11, 12, 13, 14, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 641
gccuguaaca cgagcagggt t 21


<210> 642
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1..19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 642
cgggucgucc gcgggauuct t 21


<210> 643
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 3, 7, 12, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 4, 5, 6, 8, 9, 10, 11, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 643
gccacccaag gcacagcuut t 21


<210> 644
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5, 8, 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 644
ccuguaacac gagcagggct t 21


<210> 645
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 5
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 645
gauucagcgc cgacgggact t 21


<210> 646
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 14
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 646
ccggaagugu ugauaagaut t 21


<210> 647
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 1
<223> /mod_base = "nucleoside: lacks 5'-phosphate group"

<220>
<221> modified_base
<222> 16
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<220>
<221> modified_base
<222> 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 17, 18, 19
<223> /mod_base = "2'-hydroxy corresponding nucleoside"

<400> 647
uuccggaagu guugauaagt t 21


<210> 648
<211> 21
<212> DNA
<213> Artificial sequence

<220>
<223> Description of the artificial sequence: antisense strand of dsRNA

<220>
<221> modified_base
<222> 3, 5, 7, 9, 11, 13, 15, 17, 19
<223> /mod_base = "2'-O-methyl corresponding nucleoside"

<220>
<221> modified_base
<222> 2, 4, 6, 8, 10, 12, 14, 16, 18
<223> /mod_base = "2'-deoxy-2'-fluoro corresponding nucleoside"

<220>
<221> modified_base
<222> 21
<223> /mod_base = "5'-phosphorothioate thymidine"

<400> 648
tuccggaagu guugauaagt t 21
