                         SEQUENCE LISTING

<110>  Johns Hopkins University
       Popel, Aleksander
       Rosca, Elena
       Rivera, Corban
       Pandey, Niranjan
       Tamiz, Amir
       Koskimaki, Jacob
 
<120>  Mimetic Peptides Derived from Collagen Type IV

<130>  111232-00005

<160>  35    

<170>  PatentIn version 3.5

<210>  1
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Based on human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is any natural or non-natural amino acid

<400>  1

Leu Arg Arg Phe Ser Thr Xaa Pro Xaa Xaa Xaa Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  2
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on human Collagen Type IV protein

<400>  2

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Gly Asn Ile Asn Asn 
1               5                   10                  15      


Val Gly Asn Phe 
            20  


<210>  3
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is 2-aminobutyric acid (Abu)

<400>  3

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  4
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is 2-aminobutyric acid (Abu)

<400>  4

Leu Arg Arg Phe Ser Thr Met Pro Ala Met Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  5
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is 2-aminobutyric acid (Abu)

<400>  5

Leu Arg Arg Phe Ser Thr Met Pro Phe Ala Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  6
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is 2-aminobutyric acid (Abu)

<400>  6

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Ala Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  7
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X at position 10 is Norleucine (Nle), X at position 12 is 
       2-aminobutyric acid (Abu), and X at position 18 is 2-aminobutyric
       acid (Abu)

<400>  7

Leu Arg Arg Phe Ser Thr Met Pro Phe Xaa Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  8
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X at position 11 is 4-chlorinated phenylalanine (4-ClPhe), X at 
       position 12 is 2-aminobutyric acid (Abu),  and X at position 18 
       is 2-aminobutyric acid (Abu)

<400>  8

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Xaa Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  9
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  9

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Ser Asn Ile Asn Asn 
1               5                   10                  15      


Val Ser Asn Phe 
            20  


<210>  10
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  10

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Ala Asn Ile Asn Asn 
1               5                   10                  15      


Val Ala Asn Phe 
            20  


<210>  11
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  11

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Ile Asn Ile Asn Asn 
1               5                   10                  15      


Val Ile Asn Phe 
            20  


<210>  12
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  12

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Thr Asn Ile Asn Asn 
1               5                   10                  15      


Val Thr Asn Phe 
            20  


<210>  13
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is allylglycine (AllyGly)

<400>  13

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


Val Xaa Asn Phe 
            20  


<210>  14
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  14

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Val Asn Ile Asn Asn 
1               5                   10                  15      


Val Val Asn Phe 
            20  


<210>  15
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is D-alanine

<400>  15

Leu Arg Arg Phe Ser Thr Met Pro Phe Xaa Phe Ile Asn Ile Asn Asn 
1               5                   10                  15      


Val Ile Asn Phe 
            20  


<210>  16
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  16

Leu Arg Arg Phe Ser Thr Ala Pro Phe Met Phe Ile Asn Ile Asn Asn 
1               5                   10                  15      


Val Ile Asn Phe 
            20  


<210>  17
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  17

Leu Arg Arg Phe Ser Thr Ala Pro Phe Ala Phe Ile Asn Ile Asn Asn 
1               5                   10                  15      


Val Ile Asn Phe 
            20  


<210>  18
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(20)
<223>  X is 2-aminobutyric acid (Abu)

<220>
<221>  MISC_FEATURE
<222>  (1)..(16)
<223>  X is 2-aminobutyric acid (Abu)

<400>  18

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Xaa Asn Ile Asn Val 
1               5                   10                  15      


<210>  19
<211>  19
<212>  PRT
<213>  Homo sapiens

<400>  19

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Cys Asn Ile Asn Asn 
1               5                   10                  15      


Val Cys Asn 
            


<210>  20
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(16)
<223>  X is 2-aminobutyric acid (Abu)

<400>  20

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Xaa Asn Ile Asn Asn 
1               5                   10                  15      


<210>  21
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  21

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Thr Asn Ile Asn Val 
1               5                   10                  15      


<210>  22
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  22

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Thr Asn Ile Asn Asn 
1               5                   10                  15      


<210>  23
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  23

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Ile Asn Ile Asn Asn 
1               5                   10                  15      


<210>  24
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(12)
<223>  X is 2-aminobutyric acid (Abu)

<400>  24

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe Xaa 
1               5                   10          


<210>  25
<211>  8
<212>  PRT
<213>  Homo sapiens

<400>  25

Leu Arg Arg Phe Ser Thr Met Pro 
1               5               


<210>  26
<211>  9
<212>  PRT
<213>  Homo sapiens

<400>  26

Leu Asn Arg Phe Ser Thr Met Pro Phe 
1               5                   


<210>  27
<211>  11
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(11)
<223>  X is norleucine (Nle)

<400>  27

Leu Arg Arg Phe Ser Thr Xaa Pro Phe Xaa Phe 
1               5                   10      


<210>  28
<211>  11
<212>  PRT
<213>  Homo sapiens

<400>  28

Leu Arg Arg Phe Ser Thr Met Pro Phe Met Phe 
1               5                   10      


<210>  29
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(12)
<223>  X is 2-aminobutyric acid (Abu)

<400>  29

Phe Met Phe Xaa Asn Ile Asn Asn Val Xaa Asn Phe 
1               5                   10          


<210>  30
<211>  16
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(16)
<223>  X is 2-aminobutyric acid

<400>  30

Ser Thr Met Pro Phe Met Phe Xaa Asn Ile Asn Asn Val Xaa Asn Phe 
1               5                   10                  15      


<210>  31
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(8)
<223>  X is 2-aminobutyric acid

<400>  31

Asn Ile Asn Asn Val Xaa Asn Phe 
1               5               


<210>  32
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(5)
<223>  X is 2-aminobutyric acid

<400>  32

Phe Xaa Asn Ile Asn 
1               5   


<210>  33
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(6)
<223>  X is 2-aminobutyric acid (Abu)

<400>  33

Phe Xaa Asn Ile Asn Val 
1               5       


<210>  34
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein

<400>  34

Phe Thr Asn Ile Asn Asn Val Thr Asn 
1               5                   


<210>  35
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Artificial sequence based on the human Collagen Type IV protein


<220>
<221>  MISC_FEATURE
<222>  (1)..(9)
<223>  X is 2-aminobutyric acid (Abu)

<400>  35

Phe Xaa Asn Ile Asn Asn Val Xaa Asn 
1               5                   


