                         SEQUENCE LISTING

<110>  AVI BioPharma, Inc.
       Iversen, Patrick L.
 
<120>  ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS

<130>  120178.490PC

<150>  US 61/420,636
<151>  2010-12-07

<150>  US 61/412,971
<151>  2010-11-12

<160>  42    

<170>  PatentIn version 3.5

<210>  1
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence leuD1

<400>  1
gtgaaaggct t                                                            11


<210>  2
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence leuD2

<400>  2
cttccatgct g                                                            11


<210>  3
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence leuD3

<400>  3
ctgatcccct a                                                            11


<210>  4
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence mgtC1

<400>  4
gtcagcgttt g                                                            11


<210>  5
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence mgtC2

<400>  5
tttgcatgac g                                                            11


<210>  6
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence mtgC3

<400>  6
acgccgagtc c                                                            11


<210>  7
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence pirG

<400>  7
cggttcggca c                                                            11


<210>  8
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv0194-1

<400>  8
gcaattcgtg c                                                            11


<210>  9
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv0194-2

<400>  9
tgcgcattcg c                                                            11


<210>  10
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv0194-3

<400>  10
cgccatatcc t                                                            11


<210>  11
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence pcaA1

<400>  11
gagctgcacg g                                                            11


<210>  12
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence pcaA2

<400>  12
acggacatac c                                                            11


<210>  13
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence pcaA3

<400>  13
ccgattgagc c                                                            11


<210>  14
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence cma1-1

<400>  14
cagctcgtcg g                                                            11


<210>  15
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence cma1-2

<400>  15
cgggcattgg g                                                            11


<210>  16
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence cma1-3

<400>  16
gggatagcgt a                                                            11


<210>  17
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence IL-10E4SA

<400>  17
ggagaaatcg atgctgaaga a                                                 21


<210>  18
<211>  20
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence SOCS1

<400>  18
ctggttgcgt gctaccatcc                                                   20


<210>  19
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence SOCS3


<220>
<221>  misc_feature
<222>  (17)..(17)
<223>  n = Inosine

<220>
<221>  misc_feature
<222>  (19)..(19)
<223>  n = Inosine

<400>  19
gccgctaccg catcccngng a                                                 21


<210>  20
<211>  21
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence STAT3

<400>  20
tggcttctca agatacctgc t                                                 21


<210>  21
<211>  20
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence IL-27-AUG

<400>  21
gtcacctggc ccatgtcagg                                                   20


<210>  22
<211>  20
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence IL-27E3SA

<400>  22
caatcgagat tcagcctgag                                                   20


<210>  23
<211>  20
<212>  DNA
<213>  Artificial

<220>
<223>  Host Gene Targeting Sequence TGF-beta


<220>
<221>  misc_feature
<222>  (13)..(15)
<223>  n = Inosine

<400>  23
gagggcggca tgnnngaggc                                                   20


<210>  24
<211>  11
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence (RFF)3;CP0407


<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = beta-alanine

<400>  24

Arg Phe Phe Arg Phe Phe Arg Phe Phe Xaa Xaa 
1               5                   10      


<210>  25
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence RTR


<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (12)..(12)
<223>  Xaa = beta-alanine

<400>  25

Arg Thr Arg Thr Arg Phe Leu Arg Arg Thr Xaa Xaa 
1               5                   10          


<210>  26
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence RFFR


<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = 6-aminohexanoic

<220>
<221>  MOD_RES
<222>  (12)..(12)
<223>  Xaa = beta-alanine

<400>  26

Arg Phe Phe Arg Phe Phe Arg Phe Phe Arg Xaa Xaa 
1               5                   10          


<210>  27
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence KTR


<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (12)..(12)
<223>  Xaa = beta-alanine

<400>  27

Lys Thr Arg Thr Lys Phe Leu Lys Lys Thr Xaa Xaa 
1               5                   10          


<210>  28
<211>  11
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence KFF


<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Xaa = 6-aminohexanoic

<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = beta-alanine

<400>  28

Lys Phe Phe Lys Phe Phe Lys Phe Phe Xaa Xaa 
1               5                   10      


<210>  29
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence KFFK


<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (12)..(12)
<223>  Xaa = beta-alanine

<400>  29

Lys Phe Phe Lys Phe Phe Lys Phe Phe Lys Xaa Xaa 
1               5                   10          


<210>  30
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence(RFF)2


<220>
<221>  MOD_RES
<222>  (7)..(7)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (8)..(8)
<223>  Xaa = beta-alanine

<400>  30

Arg Phe Phe Arg Phe Phe Xaa Xaa 
1               5               


<210>  31
<211>  9
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence (RFF)2R


<220>
<221>  MOD_RES
<222>  (8)..(8)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (9)..(9)
<223>  Xaa = beta-alanine

<400>  31

Arg Phe Phe Arg Phe Phe Arg Xaa Xaa 
1               5                   


<210>  32
<211>  10
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence RAhx


<220>
<221>  MOD_RES
<222>  (2)..(3)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (5)..(6)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (8)..(9)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Xaa = beta-alanine

<400>  32

Arg Asn Asn Arg Xaa Xaa Arg Xaa Xaa Xaa 
1               5                   10  


<210>  33
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide Sequence (RAhxR)4;P007


<220>
<221>  MOD_RES
<222>  (2)..(2)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (5)..(5)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (8)..(8)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (11)..(11)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (13)..(13)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (14)..(14)
<223>  Xaa = beta-alanine

<400>  33

Arg Xaa Arg Arg Xaa Arg Arg Xaa Arg Arg Xaa Arg Xaa Xaa 
1               5                   10                  


<210>  34
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  PPMO Sequence P007leuD1

<400>  34
gtgaaaggct t                                                            11


<210>  35
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv0477c-1

<400>  35
agggctttca t                                                            11


<210>  36
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv0477c-2

<400>  36
caccagggct t                                                            11


<210>  37
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv2958c-1

<400>  37
attcccgcag c                                                            11


<210>  38
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv2958c-2

<400>  38
agcacatcga a                                                            11


<210>  39
<211>  12
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv2958c-3

<400>  39
gaaaagtgcg ct                                                           12


<210>  40
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv2957-1

<400>  40
tttcgtctgc a                                                            11


<210>  41
<211>  11
<212>  DNA
<213>  Artificial

<220>
<223>  Antisense targeting sequence Rv2957-2

<400>  41
gtctgcacca t                                                            11


<210>  42
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  PPMO Sequence P007leuD1


<220>
<221>  MOD_RES
<222>  (1)..(1)
<223>  Xaa = beta-alanine

<220>
<221>  MOD_RES
<222>  (2)..(2)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (4)..(4)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (7)..(7)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (10)..(10)
<223>  Xaa = 6-aminohexanoic acid

<220>
<221>  MOD_RES
<222>  (13)..(13)
<223>  Xaa = 6-aminohexanoic acid

<400>  42

Xaa Xaa Arg Xaa Arg Arg Xaa Arg Arg Xaa Arg Arg Xaa Arg 
1               5                   10                  


