
                                SEQUENCE LISTING

<110> Merck Sharp & Dohme Corp.
      Budzik, Brian W.
      Colletti, Steven L.
      Seifried, Darla Danile
      Stanton, Matthew G.
      Tian, Lu
      
      

<120> NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR
  OLIGONUCLEOTIDE DELIVERY
  

<130> MRL-MIS-00032

<150> 61/347,640          
<151> 2010-05-24  

<160> 4

<170> FastSEQ for Windows Version 4.0

<210> 1
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<221> misc_feature   
<222> (1)...(1)
<223> 2'-deoxy

<221> misc_feature   
<222> (2)...(2)
<223> 2'-fluoro

<221> misc_feature   
<222> (3)...(6)
<223> 2'-deoxy

<221> misc_feature   
<222> (7)...(8)
<223> 2'-fluoro

<221> misc_feature   
<222> (9)...(9)
<223> 2'-deoxy

<221> misc_feature   
<222> (10)...(10)
<223> 2'-fluoro

<221> misc_feature   
<222> (11)...(17)
<223> 2'-deoxy

<221> misc_feature   
<222> (18)...(18)
<223> 2'-fluoro

<221> misc_feature   
<222> (19)...(21)
<223> 2'-deoxy

<400> 1
auaaggcuau gaagagauat t                                           21

<210> 2
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<221> misc_feature   
<222> (1)...(3)
<223> ribose

<221> misc_feature   
<222> (4)...(9)
<223> 2'-fluoro

<221> misc_feature   
<222> (10)...(10)
<223> 2'-o-methyl

<221> misc_feature   
<222> (11)...(11)
<223> 2'-fluoro

<221> misc_feature   
<222> (12)...(13)
<223> 2'-o-methyl

<221> misc_feature   
<222> (14)...(17)
<223> 2'-fluoro

<221> misc_feature   
<222> (18)...(18)
<223> 2'-o-methyl

<221> misc_feature   
<222> (19)...(19)
<223> 2'-fluoro

<221> misc_feature   
<222> (20)...(21)
<223> 2'-o-methyl

<400> 2
uuuauuccga uacuucucua u                                           21

<210> 3
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<221> misc_feature   
<222> (1)...(4)
<223> 2'-fluoro

<221> misc_feature   
<222> (5)...(6)
<223> 2'-deoxy

<221> misc_feature   
<222> (7)...(7)
<223> 2'-fluoro

<221> misc_feature   
<222> (8)...(9)
<223> 2'-deoxy

<221> misc_feature   
<222> (10)...(14)
<223> 2'-fluoro

<221> misc_feature   
<222> (15)...(18)
<223> 2'-deoxy

<221> misc_feature   
<222> (19)...(19)
<223> 2'-fluoro

<221> misc_feature   
<222> (20)...(21)
<223> 2'-deoxy

<400> 3
cuuuaacaau uccugaaaut t                                           21

<210> 4
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<221> misc_feature   
<222> (1)...(6)
<223> 2'-O-methyl

<221> misc_feature   
<222> (7)...(8)
<223> 2'-fluoro

<221> misc_feature   
<222> (9)...(9)
<223> 2'-O-methyl

<221> misc_feature   
<222> (10)...(11)
<223> 2'-fluoro

<221> misc_feature   
<222> (12)...(16)
<223> 2'-O-methyl

<221> misc_feature   
<222> (17)...(18)
<223> 2'-fluoro

<221> misc_feature   
<222> (19)...(21)
<223> ribose

<400> 4
uugaaauugu uaaggacuuu a                                           21
