                         SEQUENCE LISTING

<110>  SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
       SALK INSTITUTE OF BIOLOGICAL STUDIES
      Ruoslahti, Erkki
      Agemy, Lilach
      Friedmann-Morvinski, Dinorah
      Kotamraju, Venkata Ramana
      Sugahara, Kazuki
      Verma, Inder
      
 
<120>  METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF COMPOUNDS

<130>  SBMRI 51.9001

<150>  61/322,207
<151>  2010-04-08

<150>  61/376,856
<151>  2010-08-25

<160>  137   

<170>  PatentIn version 3.5

<210>  1
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  PEPTIDE
<222>  (1)..(5)

<400>  1

Cys Gly Lys Arg Lys 
1               5   


<210>  2
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  2

Cys Arg Lys Asp Lys Cys 
1               5       


<210>  3
<211>  14
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; membrane perturbing molecule


<220>
<221>  peptide
<222>  (1)..(14)

<400>  3

Lys Leu Ala Lys Leu Ala Lys Lys Leu Ala Lys Leu Ala Lys 
1               5                   10                  


<210>  4
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  MISC_FEATURE
<222>  (5)..(5)
<223>  X at position 5 can be either lysine or arginine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  X at position 8 can be either aspartate or glutamate

<400>  4

Cys Arg Gly Asp Xaa Gly Pro Xaa Cys 
1               5                   


<210>  5
<211>  14
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; membrane perturbing molecule


<220>
<221>  peptide
<222>  (1)..(14)

<400>  5

Lys Leu Ala Lys Lys Leu Ala Lys Leu Ala Lys Lys Leu Ala 
1               5                   10                  


<210>  6
<211>  14
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; membrane perturbing molecule


<220>
<221>  peptide
<222>  (1)..(14)

<400>  6

Lys Ala Ala Lys Lys Ala Ala Lys Ala Ala Lys Lys Ala Ala 
1               5                   10                  


<210>  7
<211>  21
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; membrane perturbing molecule


<220>
<221>  peptide
<222>  (1)..(21)

<400>  7

Lys Leu Gly Lys Lys Leu Gly Lys Leu Gly Lys Lys Leu Gly Lys Leu 
1               5                   10                  15      


Gly Lys Lys Leu Gly 
            20      


<210>  8
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  8

Cys Asn Ser Arg Leu His Leu Arg Cys 
1               5                   


<210>  9
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  9

Cys Glu Asn Trp Trp Gly Asp Val Cys 
1               5                   


<210>  10
<211>  21
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(21)

<400>  10

Trp Arg Cys Val Leu Arg Glu Gly Pro Ala Gly Gly Cys Ala Trp Phe 
1               5                   10                  15      


Asn Arg His Arg Leu 
            20      


<210>  11
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  11

Cys Leu Ser Ser Arg Leu Asp Ala Cys 
1               5                   


<210>  12
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  12

Cys Val Leu Arg Gly Gly Arg Cys 
1               5               


<210>  13
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  13

Cys Asn Ser Arg Leu Gln Leu Arg Cys 
1               5                   


<210>  14
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  14

Cys Gly Val Arg Leu Gly Cys 
1               5           


<210>  15
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  15

Cys Lys Asp Trp Gly Arg Ile Cys 
1               5               


<210>  16
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  16

Cys Leu Asp Trp Gly Arg Ile Cys 
1               5               


<210>  17
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  17

Cys Thr Arg Ile Thr Glu Ser Cys 
1               5               


<210>  18
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  18

Cys Glu Thr Leu Pro Ala Cys 
1               5           


<210>  19
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  19

Cys Arg Thr Gly Thr Leu Phe Cys 
1               5               


<210>  20
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  20

Cys Gly Arg Ser Leu Asp Ala Cys 
1               5               


<210>  21
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  21

Cys Arg His Trp Phe Asp Val Val Cys 
1               5                   


<210>  22
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  22

Cys Ala Asn Ala Gln Ser His Cys 
1               5               


<210>  23
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  23

Cys Gly Asn Pro Ser Tyr Arg Cys 
1               5               


<210>  24
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(20)

<400>  24

Tyr Pro Cys Gly Gly Glu Ala Val Ala Gly Val Ser Ser Val Arg Thr 
1               5                   10                  15      


Met Cys Ser Glu 
            20  


<210>  25
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; brain homing peptide


<220>
<221>  peptide
<222>  (1)..(20)

<400>  25

Leu Asn Cys Asp Tyr Gln Gly Thr Asn Pro Ala Thr Ser Val Ser Val 
1               5                   10                  15      


Pro Cys Thr Val 
            20  


<210>  26
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  26

Cys Leu Pro Val Ala Ser Cys 
1               5           


<210>  27
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  27

Cys Gly Ala Arg Glu Met Cys 
1               5           


<210>  28
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  28

Cys Lys Gly Arg Ser Ser Ala Cys 
1               5               


<210>  29
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide

<400>  29

Cys Trp Ala Arg Ala Gln Gly Cys 
1               5               


<210>  30
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  30

Cys Leu Gly Arg Ser Ser Val Cys 
1               5               


<210>  31
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  31

Cys Thr Ser Pro Gly Gly Ser Cys 
1               5               


<210>  32
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  32

Cys Met Gly Arg Trp Arg Leu Cys 
1               5               


<210>  33
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  33

Cys Val Gly Glu Cys Gly Gly Cys 
1               5               


<210>  34
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  34

Cys Val Ala Trp Leu Asn Cys 
1               5           


<210>  35
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  35

Cys Arg Arg Phe Gln Asp Cys 
1               5           


<210>  36
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  36

Cys Leu Met Gly Val His Cys 
1               5           


<210>  37
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  37

Cys Lys Leu Leu Ser Gly Val Cys 
1               5               


<210>  38
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  38

Cys Phe Val Gly His Asp Leu Cys 
1               5               


<210>  39
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide

<400>  39

Cys Arg Cys Leu Asn Val Cys 
1               5           


<210>  40
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; kidney homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  40

Cys Lys Leu Met Gly Glu Cys 
1               5           


<210>  41
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  41

Cys Ala Arg Ser Lys Asn Lys Asp Cys 
1               5                   


<210>  42
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  42

Cys Arg Lys Asp Lys Cys 
1               5       


<210>  43
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(13)

<400>  43

Cys Val Ala Leu Cys Arg Glu Ala Cys Gly Glu Gly Cys 
1               5                   10              


<210>  44
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(13)

<400>  44

Cys Ser Ser Gly Cys Ser Lys Asn Cys Leu Glu Met Cys 
1               5                   10              


<210>  45
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  45

Cys Ile Gly Glu Val Glu Val Cys 
1               5               


<210>  46
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  46

Cys Lys Trp Ser Arg Leu His Ser Cys 
1               5                   


<210>  47
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  47

Cys Trp Arg Gly Asp Arg Lys Ile Cys 
1               5                   


<210>  48
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  48

Cys Glu Arg Val Val Gly Ser Ser Cys 
1               5                   


<210>  49
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; skin homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  49

Cys Leu Ala Lys Glu Asn Val Val Cys 
1               5                   


<210>  50
<211>  13
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(13)

<400>  50

Cys Gly Phe Glu Cys Val Arg Gln Cys Pro Glu Arg Cys 
1               5                   10              


<210>  51
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  51

Cys Gly Phe Glu Leu Glu Thr Cys 
1               5               


<210>  52
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  52

Cys Thr Leu Arg Asp Arg Asn Cys 
1               5               


<210>  53
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  53

Cys Ile Gly Glu Val Glu Val Cys 
1               5               


<210>  54
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  54

Cys Thr Leu Arg Asp Arg Asn Cys 
1               5               


<210>  55
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide

<400>  55

Cys Gly Lys Arg Tyr Arg Asn Cys 
1               5               


<210>  56
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide

<400>  56

Cys Leu Arg Pro Tyr Leu Asn Cys 
1               5               


<210>  57
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(12)

<400>  57

Cys Thr Val Asn Glu Ala Tyr Lys Thr Arg Met Cys 
1               5                   10          


<210>  58
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide


<220>
<221>  peptide
<222>  (1)..(12)

<400>  58

Cys Arg Leu Arg Ser Tyr Gly Thr Leu Ser Leu Cys 
1               5                   10          


<210>  59
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; lung homing peptide

<400>  59

Cys Arg Pro Trp His Asn Gln Ala His Thr Glu Cys 
1               5                   10          


<210>  60
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; pancreas homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  60

Ser Trp Cys Glu Pro Gly Trp Cys Arg 
1               5                   


<210>  61
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; pancreas homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  61

Cys Lys Ala Ala Lys Asn Lys 
1               5           


<210>  62
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; pancreas homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  62

Cys Lys Gly Ala Lys Ala Arg 
1               5           


<210>  63
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; pancreas homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  63

Val Gly Val Gly Glu Trp Ser Val 
1               5               


<210>  64
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; intestine homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  64

Tyr Ser Gly Lys Trp Gly Trp 
1               5           


<210>  65
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; uterus homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  65

Gly Leu Ser Gly Gly Arg Ser 
1               5           


<210>  66
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; adrenal gland homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  66

Leu Met Leu Pro Arg Ala Asp 
1               5           


<210>  67
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; adrenal gland homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  67

Leu Pro Arg Tyr Leu Leu Ser 
1               5           


<210>  68
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; retina homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  68

Cys Ser Cys Phe Arg Asp Val Cys Cys 
1               5                   


<210>  69
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; retina homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  69

Cys Arg Asp Val Val Ser Val Ile Cys 
1               5                   


<210>  70
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  70

Tyr Ser Gly Lys Trp Gly Lys 
1               5           


<210>  71
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  71

Gly Ile Ser Ala Leu Val Leu Ser 
1               5               


<210>  72
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  72

Ser Arg Arg Gln Pro Leu Ser 
1               5           


<210>  73
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  73

Met Ser Pro Gln Leu Ala Thr 
1               5           


<210>  74
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  74

Met Arg Arg Asp Glu Gln Arg 
1               5           


<210>  75
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  75

Gln Val Arg Arg Val Pro Glu 
1               5           


<210>  76
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  76

Val Arg Arg Gly Ser Pro Gln 
1               5           


<210>  77
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  77

Gly Gly Arg Gly Ser Trp Glu 
1               5           


<210>  78
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  78

Phe Arg Val Arg Gly Ser Pro 
1               5           


<210>  79
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; gut homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  79

Arg Val Arg Gly Pro Glu Arg 
1               5           


<210>  80
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; liver homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  80

Val Lys Ser Val Cys Arg Thr 
1               5           


<210>  81
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; liver homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  81

Trp Arg Gln Asn Met Pro Leu 
1               5           


<210>  82
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; liver homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  82

Ser Arg Arg Phe Val Gly Gly 
1               5           


<210>  83
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; liver homing peptide

<400>  83

Ala Leu Glu Arg Arg Ser Leu 
1               5           


<210>  84
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; liver homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  84

Ala Arg Arg Gly Trp Thr Leu 
1               5           


<210>  85
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; prostate homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  85

Ser Met Ser Ile Ala Arg Leu 
1               5           


<210>  86
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; prostate homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  86

Val Ser Phe Leu Glu Tyr Arg 
1               5           


<210>  87
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; prostate homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  87

Arg Gly Arg Trp Leu Ala Leu 
1               5           


<210>  88
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; ovary homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  88

Glu Val Arg Ser Arg Leu Ser 
1               5           


<210>  89
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; ovary homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  89

Val Arg Ala Arg Leu Met Ser 
1               5           


<210>  90
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; ovary homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  90

Arg Val Gly Leu Val Ala Arg 
1               5           


<210>  91
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; ovary homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  91

Arg Val Arg Leu Val Asn Leu 
1               5           


<210>  92
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; clot binding/homing peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  92

Cys Arg Glu Lys Ala 
1               5   


<210>  93
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  93

Cys Arg Pro Pro Arg 
1               5   


<210>  94
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  94

Cys Gly Arg Lys Ser Lys Thr Val Cys 
1               5                   


<210>  95
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  95

Cys Ala Arg Pro Ala Arg 
1               5       


<210>  96
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  96

Cys Pro Lys Arg Pro Arg 
1               5       


<210>  97
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  97

Cys Lys Arg Ala Val Arg 
1               5       


<210>  98
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  98

Cys Arg Asn Ser Trp Lys Pro Asn Cys 
1               5                   


<210>  99
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  99

Arg Gly Ser Ser Ser 
1               5   


<210>  100
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  100

Cys Arg Ser Thr Arg Ala Asn Pro Cys 
1               5                   


<210>  101
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  101

Cys Pro Lys Thr Arg Arg Val Pro Cys 
1               5                   


<210>  102
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide

<400>  102

Cys Ser Gly Met Ala Arg Thr Lys Cys 
1               5                   


<210>  103
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  103

Gly Gly Gly Val Phe Trp Gln 
1               5           


<210>  104
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide

<400>  104

His Gly Arg Val Arg Pro His 
1               5           


<210>  105
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  105

Val Val Leu Val Thr Ser Ser 
1               5           


<210>  106
<211>  8
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(8)

<400>  106

Cys Leu His Arg Gly Asn Ser Cys 
1               5               


<210>  107
<211>  12
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(12)

<400>  107

Cys Arg Ser Trp Asn Lys Ala Asp Asn Arg Ser Cys 
1               5                   10          


<210>  108
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  108

Cys Gly Arg Lys Ser Lys Thr Val Cys 
1               5                   


<210>  109
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  109

Cys Lys Arg Ala Val Arg 
1               5       


<210>  110
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  110

Cys Arg Asn Ser Trp Lys Pro Asn Cys 
1               5                   


<210>  111
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  111

Cys Pro Lys Thr Arg Arg Val Pro Cys 
1               5                   


<210>  112
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  112

Cys Ser Gly Met Ala Arg Thr Lys Cys 
1               5                   


<210>  113
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  113

Cys Ala Arg Pro Ala Arg 
1               5       


<210>  114
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; heart homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  114

Cys Pro Lys Arg Pro Arg 
1               5       


<210>  115
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor blood vessel homing peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  115

Cys Asn Gly Arg Cys 
1               5   


<210>  116
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  116

Cys Ser Arg Pro Arg Arg Ser Glu Cys 
1               5                   


<210>  117
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  117

Cys Ser Arg Pro Arg Arg Ser Val Cys 
1               5                   


<210>  118
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  118

Cys Ser Arg Pro Arg Arg Ser Trp Cys 
1               5                   


<210>  119
<211>  31
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(31)

<400>  119

Lys Asp Glu Pro Gln Arg Arg Ser Ala Arg Leu Ser Ala Lys Pro Ala 
1               5                   10                  15      


Pro Pro Lys Pro Glu Pro Lys Pro Lys Lys Ala Pro Ala Lys Lys 
            20                  25                  30      


<210>  120
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(10)

<400>  120

Pro Gln Arg Arg Ser Ala Arg Leu Ser Ala 
1               5                   10  


<210>  121
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide

<400>  121

Pro Lys Arg Arg Ser Ala Arg Leu Ser Ala 
1               5                   10  


<210>  122
<211>  7
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(7)

<400>  122

Cys Arg Gly Arg Arg Ser Thr 
1               5           


<210>  123
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  123

Cys Ala Arg Ser Lys Asn Lys Asp Cys 
1               5                   


<210>  124
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  124

Cys Arg Lys Asp Lys Cys 
1               5       


<210>  125
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(10)

<400>  125

Cys Gly Leu Ile Ile Gln Lys Asn Glu Cys 
1               5                   10  


<210>  126
<211>  10
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(10)

<400>  126

Cys Asn Ala Gly Glu Ser Ser Lys Asn Cys 
1               5                   10  


<210>  127
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  127

Cys Gly Asn Lys Arg Thr Arg Gly Cys 
1               5                   


<210>  128
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  128

Cys Ala Arg Ser Lys Asn Lys Asp Cys 
1               5                   


<210>  129
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  129

Cys Arg Lys Asp Lys Cys 
1               5       


<210>  130
<211>  4
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; internalization sequence


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  X at position 1 can be either arginine, lysine or histidine

<220>
<221>  MISC_FEATURE
<222>  (2)..(2)
<223>  X at position 2 can be any amino acid

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  X at position 3 can be any amino acid

<220>
<221>  MISC_FEATURE
<222>  (4)..(4)
<223>  X at position 4 can be either arginine, lysine or histidine

<400>  130

Xaa Xaa Xaa Xaa 
1               


<210>  131
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; internalization sequence


<220>
<221>  peptide
<222>  (1)..(1)
<223>  X at position 1 can be either arginine, lysine or histidine

<220>
<221>  peptide
<222>  (2)..(2)
<223>  X at position 2 can be any amino acid

<220>
<221>  peptide
<222>  (3)..(3)
<223>  X at position 3 can be any amino acid

<400>  131

Xaa Xaa Xaa Lys Gly 
1               5   


<210>  132
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  132

Cys Asn Arg Arg Thr Lys Ala Gly Cys 
1               5                   


<210>  133
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(6)

<400>  133

Cys Arg Ser Arg Lys Gly 
1               5       


<210>  134
<211>  9
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide


<220>
<221>  peptide
<222>  (1)..(9)

<400>  134

Cys Arg Gly Asp Lys Gly Pro Asp Cys 
1               5                   


<210>  135
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; control peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  135

Lys Ala Lys Glu Cys 
1               5   


<210>  136
<211>  5
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; homing peptide


<220>
<221>  peptide
<222>  (1)..(5)

<400>  136

Cys Arg Gly Asp Cys 
1               5   


<210>  137
<211>  34
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  chemically synthesized; tumor homing peptide

<400>  137

Ala Lys Val Lys Asp Glu Pro Gln Arg Arg Ser Ala Arg Leu Ser Ala 
1               5                   10                  15      


Lys Pro Ala Pro Pro Lys Pro Glu Pro Lys Pro Lys Lys Ala Pro Ala 
            20                  25                  30          


Lys Lys 
        


