                         SEQUENCE LISTING

<110>  Universit degli Studi di Modena e Reggio Emilia
       EML RESEARCH GmbH
 
<120>  Peptides binding to the dimer interface of thymidylate synthase 
       for the treatment of cancer

<130>  61.U2310.12.WO.4

<160>  186   

<170>  PatentIn version 3.3

<210>  1
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  1

Asp Phe Ile His Thr Leu Gly Asp 
1               5               


<210>  2
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS


<220>
<221>  MOD_RES
<222>  (1)..(1)
<223>  ACETYLATION

<400>  2

Asp Phe Ile His Thr Leu Gly Asp 
1               5               


<210>  3
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS


<220>
<221>  MOD_RES
<222>  (8)..(8)
<223>  AMIDATION

<400>  3

Asp Phe Ile His Thr Leu Gly Asp 
1               5               


<210>  4
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS


<220>
<221>  MOD_RES
<222>  (1)..(1)
<223>  ACETYLATION

<220>
<221>  MOD_RES
<222>  (8)..(8)
<223>  AMIDATION

<400>  4

Asp Phe Ile His Thr Leu Gly Asp 
1               5               


<210>  5
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  5

Ala Phe Ile His Thr Leu Gly Asp 
1               5               


<210>  6
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  6

Asp Ala Ile His Thr Leu Gly Asp 
1               5               


<210>  7
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  7

Asp Phe Ala His Thr Leu Gly Asp 
1               5               


<210>  8
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  8

Asp Phe Ile Ala Thr Leu Gly Asp 
1               5               


<210>  9
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  9

Asp Phe Ile His Ala Leu Gly Asp 
1               5               


<210>  10
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  10

Asp Phe Ile His Thr Ala Gly Asp 
1               5               


<210>  11
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  11

Asp Phe Ile His Thr Leu Ala Asp 
1               5               


<210>  12
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  12

Asp Phe Ile His Thr Leu Gly Ala 
1               5               


<210>  13
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  13

Phe Ile His Thr Leu Gly Asp 
1               5           


<210>  14
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  14

Ile His Thr Leu Gly Asp 
1               5       


<210>  15
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  15

His Thr Leu Gly Asp 
1               5   


<210>  16
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  16

Asp Phe Ile His Thr Leu Gly 
1               5           


<210>  17
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  17

Asp Phe Ile His Thr Leu 
1               5       


<210>  18
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  18

Asp Phe Ile His Thr 
1               5   


<210>  19
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  19

Phe Ile His Thr Leu 
1               5   


<210>  20
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  20

Ile His Thr Leu Gly 
1               5   


<210>  21
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  21

Leu Lys Tyr Val Trp Asn Pro Leu 
1               5               


<210>  22
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  22

Leu Lys Tyr Val Cys Asn Pro Leu 
1               5               


<210>  23
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  23

Val Lys Tyr Val Ser Gln Ser Ile 
1               5               


<210>  24
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  24

Leu Ser Cys Gln Leu Tyr Gln Arg 
1               5               


<210>  25
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  25

Ala Ser Cys Gln Leu Tyr Gln Arg 
1               5               


<210>  26
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  26

Leu Ala Cys Gln Leu Tyr Gln Arg 
1               5               


<210>  27
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  27

Leu Ser Ala Gln Leu Tyr Gln Arg 
1               5               


<210>  28
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  28

Leu Ser Cys Ala Leu Tyr Gln Arg 
1               5               


<210>  29
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  29

Leu Ser Cys Gln Ala Tyr Gln Arg 
1               5               


<210>  30
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  30

Leu Ser Cys Gln Leu Ala Gln Arg 
1               5               


<210>  31
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  31

Leu Ser Cys Gln Leu Tyr Ala Arg 
1               5               


<210>  32
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  32

Leu Ser Cys Gln Leu Tyr Gln Ala 
1               5               


<210>  33
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  33

Ser Cys Gln Leu Tyr Gln Arg 
1               5           


<210>  34
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  34

Cys Gln Leu Tyr Gln Arg 
1               5       


<210>  35
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  35

Gln Leu Tyr Gln Arg 
1               5   


<210>  36
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  36

Leu Ser Cys Gln Leu Tyr Gln 
1               5           


<210>  37
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  37

Leu Ser Cys Gln Leu Tyr 
1               5       


<210>  38
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  38

Leu Ser Cys Gln Leu 
1               5   


<210>  39
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  39

Ser Cys Gln Leu Tyr 
1               5   


<210>  40
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  40

Cys Gln Leu Tyr Gln 
1               5   


<210>  41
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  41

Leu Ser Ser Gln Leu Tyr Gln Arg 
1               5               


<210>  42
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  42

Asp Arg Thr Val Asp Met Val Ser 
1               5               


<210>  43
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  43

Gln Gly Ala Leu Gln Val Leu Ser 
1               5               


<210>  44
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  44

Tyr Val Val Asn Ser Glu Leu Ser 
1               5               


<210>  45
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  45

Ala Val Val Asn Ser Glu Leu Ser 
1               5               


<210>  46
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  46

Tyr Ala Val Asn Ser Glu Leu Ser 
1               5               


<210>  47
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  47

Tyr Val Ala Asn Ser Glu Leu Ser 
1               5               


<210>  48
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  48

Tyr Val Val Ala Ser Glu Leu Ser 
1               5               


<210>  49
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  49

Tyr Val Val Asn Ala Glu Leu Ser 
1               5               


<210>  50
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  50

Tyr Val Val Asn Ser Ala Leu Ser 
1               5               


<210>  51
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  51

Tyr Val Val Asn Ser Glu Ala Ser 
1               5               


<210>  52
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  52

Tyr Val Val Asn Ser Glu Leu Ala 
1               5               


<210>  53
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  53

Val Val Asn Ser Glu Leu Ser 
1               5           


<210>  54
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  54

Val Asn Ser Glu Leu Ser 
1               5       


<210>  55
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  55

Asn Ser Glu Leu Ser 
1               5   


<210>  56
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  56

Tyr Val Val Asn Ser Glu Leu 
1               5           


<210>  57
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  57

Tyr Val Val Asn Ser Glu 
1               5       


<210>  58
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  58

Tyr Val Val Asn Ser 
1               5   


<210>  59
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  59

Val Val Asn Ser Glu 
1               5   


<210>  60
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  60

Val Asn Ser Glu Leu 
1               5   


<210>  61
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  61

Ile His His Leu Ser Leu Asp Arg 
1               5               


<210>  62
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  62

Ile His His Val Thr Leu Gln Gly 
1               5               


<210>  63
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  63

Cys Gln Leu Tyr Gln Arg Ser Gly 
1               5               


<210>  64
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  64

Ala Gln Leu Tyr Gln Arg Ser Gly 
1               5               


<210>  65
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  65

Cys Ala Leu Tyr Gln Arg Ser Gly 
1               5               


<210>  66
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  66

Cys Gln Ala Tyr Gln Arg Ser Gly 
1               5               


<210>  67
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  67

Cys Gln Leu Ala Gln Arg Ser Gly 
1               5               


<210>  68
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  68

Cys Gln Leu Tyr Ala Arg Ser Gly 
1               5               


<210>  69
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  69

Cys Gln Leu Tyr Gln Ala Ser Gly 
1               5               


<210>  70
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  70

Cys Gln Leu Tyr Gln Arg Ala Gly 
1               5               


<210>  71
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  71

Cys Gln Leu Tyr Gln Arg Ser Ala 
1               5               


<210>  72
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  72

Gln Leu Tyr Gln Arg Ser Gly 
1               5           


<210>  73
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  73

Leu Tyr Gln Arg Ser Gly 
1               5       


<210>  74
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  74

Tyr Gln Arg Ser Gly 
1               5   


<210>  75
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  75

Cys Gln Leu Tyr Gln Arg Ser 
1               5           


<210>  76
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  76

Cys Gln Leu Tyr Gln Arg 
1               5       


<210>  77
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  77

Cys Gln Leu Tyr Gln 
1               5   


<210>  78
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  78

Gln Leu Tyr Gln Arg 
1               5   


<210>  79
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  79

Leu Tyr Gln Arg Ser 
1               5   


<210>  80
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  80

Ser Gln Leu Tyr Gln Arg Ser Gly 
1               5               


<210>  81
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  81

Thr Val Asp Met Val Ser Ser Pro 
1               5               


<210>  82
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  82

Ala Leu Gln Val Leu Ser Arg Ser 
1               5               


<210>  83
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  83

Gln Phe Tyr Val Val Asn Ser Glu 
1               5               


<210>  84
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  84

Val Asn Ser Glu Leu Ser Cys Gln 
1               5               


<210>  85
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  85

Ser Glu Leu Ser Cys Gln Leu Tyr 
1               5               


<210>  86
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  86

Leu Cys Gln Phe Tyr Val Val Asn 
1               5               


<210>  87
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  87

Ala Cys Gln Phe Tyr Val Val Asn 
1               5               


<210>  88
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  88

Leu Ala Gln Phe Tyr Val Val Asn 
1               5               


<210>  89
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  89

Leu Cys Ala Phe Tyr Val Val Asn 
1               5               


<210>  90
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  90

Leu Cys Gln Ala Tyr Val Val Asn 
1               5               


<210>  91
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  91

Leu Cys Gln Phe Ala Val Val Asn 
1               5               


<210>  92
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  92

Leu Cys Gln Phe Tyr Ala Val Asn 
1               5               


<210>  93
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  93

Leu Cys Gln Phe Tyr Val Ala Asn 
1               5               


<210>  94
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  94

Leu Cys Gln Phe Tyr Val Val Ala 
1               5               


<210>  95
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  95

Cys Gln Phe Tyr Val Val Asn 
1               5           


<210>  96
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  96

Gln Phe Tyr Val Val Asn 
1               5       


<210>  97
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  97

Phe Tyr Val Val Asn 
1               5   


<210>  98
<211>  7
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  98

Leu Cys Gln Phe Tyr Val Val 
1               5           


<210>  99
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  99

Leu Cys Gln Phe Tyr Val 
1               5       


<210>  100
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  100

Leu Cys Gln Phe Tyr 
1               5   


<210>  101
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  101

Cys Gln Phe Tyr Val 
1               5   


<210>  102
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  102

Gln Phe Tyr Val Val 
1               5   


<210>  103
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  103

Leu Ser Gln Phe Tyr Val Val Asn 
1               5               


<210>  104
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  104

Glu Thr Val Lys Ile His His Leu 
1               5               


<210>  105
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  105

Glu Ala Leu Glu Ile His His Val 
1               5               


<210>  106
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  106

Pro Pro Cys His Ala 
1               5   


<210>  107
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  107

Pro Pro Ser His Ala 
1               5   


<210>  108
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  108

Gly Gly Thr Val Arg 
1               5   


<210>  109
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  109

Arg Trp Ala Met Gly 
1               5   


<210>  110
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  110

Asp Asp Arg Thr Gly Thr Gly Thr 
1               5               


<210>  111
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide bindingt o TS

<400>  111

Leu Leu Ala Cys Pro Trp Pro Trp 
1               5               


<210>  112
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  112

Val Val Ala Arg Ala Gly Ala Gly 
1               5               


<210>  113
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  113

Val Asp Gln 
1           


<210>  114
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  114

Gln Leu Val 
1           


<210>  115
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  115

Asn Val Leu 
1           


<210>  116
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  116

Asp Asp Arg 
1           


<210>  117
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  117

Leu Leu Ser 
1           


<210>  118
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  118

Val Val Ser 
1           


<210>  119
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  119

Arg Ile Ile Met Cys 
1               5   


<210>  120
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  120

Arg Ile Ile Met Ser 
1               5   


<210>  121
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  121

Ser Tyr Tyr Tyr Thr 
1               5   


<210>  122
<211>  5
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  122

Ser Asp Asp His Ala 
1               5   


<210>  123
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  123

Val Arg Lys 
1           


<210>  124
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  124

Gln Ser Phe 
1           


<210>  125
<211>  3
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  125

Asp Pro Leu 
1           


<210>  126
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  126

Ser Val Phe Gly Met Gln 
1               5       


<210>  127
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  127

Ser His Lys Pro Tyr Val 
1               5       


<210>  128
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  128

Arg Tyr Glu Ala His Leu 
1               5       


<210>  129
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  129

Trp Asn Pro Arg Asp Leu 
1               5       


<210>  130
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  130

Thr Leu Gly Ser Leu Glu 
1               5       


<210>  131
<211>  6
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  131

Pro Ile Trp Ser Ile Lys 
1               5       


<210>  132
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  132

Asp Asp Arg Arg Ile Ile Met Cys 
1               5               


<210>  133
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  133

Asp Asp Arg Arg Ile Ile Met Ser 
1               5               


<210>  134
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  134

Leu Leu Ser Ser Tyr Tyr Tyr Thr 
1               5               


<210>  135
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  135

Val Val Ser Ser Asp Asp His Ala 
1               5               


<210>  136
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  136

Arg Asp Trp Arg Lys Gly Lys His 
1               5               


<210>  137
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  137

Ile Ile Cys Trp Cys Cys Gly Val 
1               5               


<210>  138
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  138

Asn Trp Gly Gly Cys Ile Lys Arg 
1               5               


<210>  139
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  139

Arg Gly Cys Arg Thr Cys Val Cys 
1               5               


<210>  140
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  140

Cys Trp Gly Met Asp Cys Arg Asp 
1               5               


<210>  141
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  141

Cys Arg Lys Arg Ile Asp Trp Trp 
1               5               


<210>  142
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  142

Cys Cys Arg Gly Gly Phe Ile Ile 
1               5               


<210>  143
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  143

Asp Cys Asp Cys Ile Gly Glu Trp 
1               5               


<210>  144
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  144

Trp Arg Asp Ile Tyr Gly Cys Trp 
1               5               


<210>  145
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  145

Arg Ile Arg Arg Trp Arg Arg Ile 
1               5               


<210>  146
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  146

Gly Asp Lys Lys Gly Asp Arg Val 
1               5               


<210>  147
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  147

Leu Arg Lys Cys Arg Arg Asp Asp 
1               5               


<210>  148
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  148

Arg Ile Gly Arg Gly Ile Cys Arg 
1               5               


<210>  149
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  149

Gly Gly Gly Gly Lys Ile Leu Trp 
1               5               


<210>  150
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  150

Gly Cys Asp Trp Gly Lys His Arg 
1               5               


<210>  151
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  151

Glu Trp Lys Glu Arg Trp Gly Trp 
1               5               


<210>  152
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  152

Ile Trp Ile Gly Trp Asp Gly Trp 
1               5               


<210>  153
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  153

Trp Ile Arg Asp Gly Val Gly Gly 
1               5               


<210>  154
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  154

Arg Gly Lys Cys Trp Cys Cys Arg 
1               5               


<210>  155
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  155

Arg Asp Trp Cys Cys Phe Gly Arg 
1               5               


<210>  156
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  156

Cys Lys Cys Asp Met Trp Lys Trp 
1               5               


<210>  157
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  157

Arg Asp Gly Val Trp Arg Cys Glu 
1               5               


<210>  158
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  158

Trp Asp Ile Arg Asp Trp Phe Trp 
1               5               


<210>  159
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  159

Cys Cys Cys Cys Arg Trp Trp Ala 
1               5               


<210>  160
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  160

Gly Trp Lys Trp Cys Ile Trp Cys 
1               5               


<210>  161
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  161

Gly Arg Val Ile Ile Cys Gly Lys 
1               5               


<210>  162
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  162

Phe His Gly Asp Arg His Ile Arg 
1               5               


<210>  163
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  163

Cys Glu Arg Arg Asp Ile Asp Lys 
1               5               


<210>  164
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  164

Gly Val Ile Leu Arg Ile Asp Cys 
1               5               


<210>  165
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  165

His Trp Trp Trp Gly Phe Cys Trp 
1               5               


<210>  166
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  166

Asn Val Trp Val Arg Arg Ile Arg 
1               5               


<210>  167
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  167

Cys Gly Arg Trp Pro Gly Gly Cys 
1               5               


<210>  168
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  168

Trp Cys Arg Trp Trp Phe Trp Gly 
1               5               


<210>  169
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  169

Ile Lys Ile Leu Gly Trp Asp Trp 
1               5               


<210>  170
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  170

Trp Gly Trp Gly Ile Leu Lys Arg 
1               5               


<210>  171
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  171

Trp Cys Val Trp Ile Arg Arg Tyr 
1               5               


<210>  172
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  172

Asp Gly Gly Trp Cys Arg Gly Ile 
1               5               


<210>  173
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  173

Trp Gly Arg Ile Asn Trp Arg Phe 
1               5               


<210>  174
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  174

Arg Arg Met Cys Trp Leu Arg Gly 
1               5               


<210>  175
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  175

Arg Arg Gly Trp Val Ile Ile Pro 
1               5               


<210>  176
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  176

Gly Gly Phe Asp Val Asp Asp Asp 
1               5               


<210>  177
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binidng to TS

<400>  177

Ile Pro Cys Lys Trp Arg Gly Cys 
1               5               


<210>  178
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  178

Ile Leu Asp Arg Cys Arg Trp Asp 
1               5               


<210>  179
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  179

Trp Cys Arg Gly Gly Cys Phe Cys 
1               5               


<210>  180
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  180

Cys Arg Asp Lys Val Trp Gly Gly 
1               5               


<210>  181
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  181

Gly Ile Lys Arg Trp Phe Ile Arg 
1               5               


<210>  182
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  182

Ile Cys Val Arg Ile Val Cys Ile 
1               5               


<210>  183
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  183

Cys Phe Ile Phe Ile Gly Trp Leu 
1               5               


<210>  184
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binidng to TS

<400>  184

Ile Lys Trp Cys Gly Gly Val Lys 
1               5               


<210>  185
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  185

Cys Asp Cys Ile Arg Gly Gly Arg 
1               5               


<210>  186
<211>  325
<212>  PRT
<213>  Artificial

<220>
<223>  peptide binding to TS

<400>  186

Met Arg Gly Ser His His His His His His Gly Ser Met Pro Val Ala 
1               5                   10                  15      


Gly Ser Glu Leu Pro Arg Arg Pro Leu Pro Pro Ala Ala Gln Glu Arg 
            20                  25                  30          


Asp Ala Glu Pro Arg Pro Pro His Gly Glu Leu Gln Tyr Leu Gly Gln 
        35                  40                  45              


Ile Gln His Ile Leu Arg Cys Gly Val Arg Lys Asp Asp Arg Thr Gly 
    50                  55                  60                  


Thr Gly Thr Leu Ser Val Phe Gly Met Gln Ala Arg Tyr Ser Leu Arg 
65                  70                  75                  80  


Asp Glu Phe Pro Leu Leu Thr Thr Lys Arg Val Phe Trp Lys Gly Val 
                85                  90                  95      


Leu Glu Glu Leu Leu Trp Phe Ile Lys Gly Ser Thr Asn Ala Lys Glu 
            100                 105                 110         


Leu Ser Ser Lys Gly Val Lys Ile Trp Asp Ala Asn Gly Ser Arg Asp 
        115                 120                 125             


Phe Leu Asp Ser Leu Gly Phe Ser Thr Arg Glu Glu Gly Asp Leu Gly 
    130                 135                 140                 


Pro Val Tyr Gly Phe Gln Trp Arg His Phe Gly Ala Glu Tyr Arg Asp 
145                 150                 155                 160 


Met Glu Ser Asp Tyr Ser Gly Gln Gly Val Asp Gln Leu Gln Arg Val 
                165                 170                 175     


Ile Asp Thr Ile Lys Thr Asn Pro Asp Asp Arg Arg Ile Ile Met Cys 
            180                 185                 190         


Ala Trp Asn Pro Arg Asp Leu Pro Leu Met Ala Leu Pro Pro Cys His 
        195                 200                 205             


Ala Leu Cys Gln Phe Tyr Val Val Asn Ser Glu Leu Ser Cys Gln Leu 
    210                 215                 220                 


Tyr Gln Arg Ser Gly Asp Met Gly Leu Gly Val Pro Phe Asn Ile Ala 
225                 230                 235                 240 


Ser Tyr Ala Leu Leu Thr Tyr Met Ile Ala His Ile Thr Gly Leu Lys 
                245                 250                 255     


Pro Gly Asp Phe Ile His Thr Leu Gly Asp Ala His Ile Tyr Leu Asn 
            260                 265                 270         


His Ile Glu Pro Leu Lys Ile Gln Leu Gln Arg Glu Pro Arg Pro Phe 
        275                 280                 285             


Pro Lys Leu Arg Ile Leu Arg Lys Val Glu Lys Ile Asp Asp Phe Lys 
    290                 295                 300                 


Ala Glu Asp Phe Gln Ile Glu Gly Tyr Asn Pro His Pro Thr Ile Lys 
305                 310                 315                 320 


Met Glu Met Ala Val 
                325 


