                         SEQUENCE LISTING

<110>  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
       CAUSSIL-AMBLARD, MURIEL
       MARTINEZ, JEAN
       TAILHADES, JULIEN
 
<120>  Solid phase peptide synthesis of peptide alcohols

<130>  356510 D27459

<160>  7     

<170>  PatentIn version 3.5

<210>  1
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Peptide alcohol : gramicidin A derivative; Leu 2 and 4 are of the
       D serie; the terminal COOH is replaced by CH2OH on Gly 6

<400>  1

Trp Leu Trp Leu Trp Gly 
1               5       


<210>  2
<211>  11
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide alcohol : trichogin GA IV derivative; the terminal COOH 
       is replaced by CH2OH on Leu11;


<220>
<221>  misc_feature
<222>  (1)..(11)
<223>  Xaa=2-aminoisobutyric acid

<400>  2

Xaa Gly Leu Xaa Gly Gly Leu Xaa Gly Ile Leu 
1               5                   10      


<210>  3
<211>  8
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide alcohol : octrotide; Phe1 is (D); Cys 2 and cys 7 are 
       linked together by a disulphur bridge; Trp 4 is (D); the terminal
       COOH is replaced by CH2OH on Thr 8.

<400>  3

Phe Cys Phe Trp Lys Thr Cys Thr 
1               5               


<210>  4
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide alcohol : Isogalanin; Trp 8 is (D); Ala 15 is inversed in
       the way O-CH2-CH(CH3)-NH2

<400>  4

Gly Trp Thr Leu Asn Ala Ala Trp Tyr Leu Leu Gly Pro His Ala 
1               5                   10                  15  


<210>  5
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  Peptide alcohol: galanin; Trp 8 is (D); the terminal COOH is 
       replaced by CH2OH on Ala 15.

<400>  5

Gly Trp Thr Leu Asn Ala Ala Trp Tyr Leu Leu Gly Pro His Ala 
1               5                   10                  15  


<210>  6
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  Trp2 and Trp8 are substituted by a Boc group; Thr 3 and Tyr9 are 
       substituted by a tBu group;  Asn5 and His14 are substituted by a
       Trt group; Trp8 is (D);  Ala15 is inversed in the way 
       0-CH2-CH(CH3)-NH-; Ala15 is linked to Trityl resin via its NH-

<400>  6

Gly Trp Thr Leu Asn Ala Ala Trp Tyr Leu Leu Gly Pro His Ala 
1               5                   10                  15  


<210>  7
<211>  15
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  Trp8 is of the D series; Ala15 is inversed in the following way :
       O-CH2-CH(CH3)-NH3+; the amine group of Ala1 is protonated.

<400>  7

Gly Trp Thr Leu Asn Ala Ala Trp Tyr Leu Leu Gly Pro His Ala 
1               5                   10                  15  


