                               SEQUENCE LISTING                               

<110> KANDIMALLA, EKAMBAR R.
      ZHU, FU-GANG
      AGRAWAL, SUDHIR

<120> USE OF INHIBITORS OF TOLL-LIKE RECEPTORS IN THE PREVENTION
      AND TREATMENT OF HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA AND
      DISEASES RELATED THERETO

<130> 09-1052-WO

<140>
<141>

<150> 60/102,974
<151> 2008-10-06

<160> 101                           

<170> PatentIn Ver. 3.3

<210> 1
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 1
ctatctgacg ttctctgt                                               18    


<210> 2
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 2
ctatctgtcg ttctctgt                                               18    


<210> 3
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-G

<400> 3
tctgacnttc t                                                      11    


<210> 4
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 4
ctatctcacc ttctctgt                                               18    


<210> 5
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<400> 5
ctatctgacg ttctctgt                                               18    


<210> 6
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (11)..(12)
<223> 2'-OMe

<400> 6
ctatctgacg uuctctgt                                               18    


<210> 7
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (8)
<223> 2'-OMe

<400> 7
ctatctgacg ttctctgt                                               18    


<210> 8
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 8
tgaccggtca                                                        10    


<210> 9
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (8)
<223> 2'-OMe

<400> 9
ctatctgucg ttctctgt                                               18    


<210> 10
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<400> 10
ctatctgucg ttctctgt                                               18    


<210> 11
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 11
tcaaccacac a                                                      11    


<210> 12
<211> 15
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 12
tcctggcggg gaagt                                                  15    


<210> 13

<400> 13
000                                                           


<210> 14

<400> 14
000                                                             


<210> 15

<400> 15
000                                                             


<210> 16

<400> 16
000                                                         


<210> 17
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<400> 17
ctatctgacn ttctctgt                                               18    


<210> 18

<400> 18
000                                                     


<210> 19
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<400> 19
ctatctgucn ttctctgt                                               18    


<210> 20

<400> 20
000                                                           


<210> 21
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 21
tctgacgttc t                                                      11    


<210> 22
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 22
cgttctctgt                                                        10    


<210> 23
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 23
acgttctctg t                                                      11    


<210> 24
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 24
cgttctctgt                                                        10    



<210> 25
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (9)
<223> B-L-deoxy nucleoside-C

<400> 25
ctatctgang ttctctgt                                               18    


<210> 26
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> B-L-deoxy nucleoside-G

<400> 26
ctatctgacn ttctctgt                                               18    


<210> 27
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (9)
<223> B-L-deoxy nucleoside-C

<400> 27
ctatctgtng ttctctgt                                               18    


<210> 28
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> B-L-deoxy nucleoside-G

<400> 28
ctatctgtcn ttctctgt                                               18    


<210> 29
<211> 8
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 29
ctatctga                                                          8     


<210> 30
<211> 9
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 30
ctatctgac                                                         9     


<210> 31
<211> 8
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 31
ctatctgt                                                          8     


<210> 32
<211> 9
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 32
ctatctgtc                                                         9     


<210> 33
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (9)
<223> 3'-deoxy-nucleoside-C

<400> 33
ctatctgang ttctctgt                                               18    


<210> 34
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> 3'-deoxy-nucleoside-G

<400> 34
ctatctgacn ttctctgt                                               18    


<210> 35
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (9)
<223> 3'-deoxy-nucleoside-C

<400> 35
ctatctgtng ttctctgt                                               18    


<210> 36
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> 3'-deoxy-nucleoside-G

<400> 36
ctatctgtcn ttctctgt                                               18    


<210> 37
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> araG

<400> 37
ctatctgacn ttctctgt                                               18    


<210> 38
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> araG

<400> 38
ctatctgucn ttctctgt                                               18    


<210> 39
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> araC

<400> 39
ctatctgang ttctctgt                                               18    


<210> 40
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> araC

<400> 40
ctatctgung ttctctgt                                               18    


<210> 41
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> 5-OH-dC

<400> 41
ctatctgang ttctctgt                                               18    


<210> 42
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> 5-OH-dC

<400> 42
ctatctgung ttctctgt                                               18    


<210> 43
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> 1-(2'-deoxy-beta-D-ribofuranosyl)-2-oxo-7-deaza-8-
      methyl-purine-C

<400> 43
ctatctgang ttctctgt                                               18    


<210> 44
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> 1-(2'-deoxy-beta-D-ribofuranosyl)-2-oxo-7-deaza-8-
      methyl-purine-C

<400> 44
ctatctgung ttctctgt                                               18    


<210> 45
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> N1-Me-dG

<400> 45
ctatctgacn ttctctgt                                               18    


<210> 46
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> N1-Me-dG

<400> 46
ctatctgucn ttctctgt                                               18    


<210> 47
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> N3-Me-dC

<400> 47
ctatctgang ttctctgt                                               18    


<210> 48
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (9)
<223> N3-Me-dC

<400> 48
ctatctgung ttctctgt                                               18    


<210> 49
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (12)
<223> 2'-OMe

<400> 49
ctatctagcg ttctctgt                                               18    


<210> 50
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (11)
<223> 2'-OMe

<400> 50
ctatctagcg ttctctgt                                               18    


<210> 51
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (11)..(12)
<223> 2'-OMe

<400> 51
ctatctagcg ttctctgt                                               18    


<210> 52
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 52
cctactagcg t                                                      11    


<210> 53
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 53
cctactagcg                                                        10    


<210> 54
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (8)
<223> 3'-deoxy-nucleoside-G

<400> 54
cctactancg ttctcatc                                               18    


<210> 55
<211> 19
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)
<223> 3'-OMe-A

<400> 55
tccatgncgt tcctgatgc                                              19    


<210> 56
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (9)
<223> B-L-deoxy-nucleoside-C

<220> 
<221> modified_base
<222> (10)
<223> B-L-deoxy nucleoside-G

<400> 56
ctatctgann ttctctgt                                               18    


<210> 57
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (1)
<223> B-L-deoxy nucleoside-C

<220> 
<221> modified_base
<222> (2)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (3)
<223> B-L-deoxy nucleoside-A

<220> 
<221> modified_base
<222> (4)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (5)
<223> B-L-deoxy nucleoside-C

<220> 
<221> modified_base
<222> (6)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (7)
<223> B-L-deoxy nucleoside-G

<220> 
<221> modified_base
<222> (8)
<223> B-L-deoxy nucleoside-A

<220> 
<221> modified_base
<222> (9)
<223> B-L-deoxy nucleoside-C

<220> 
<221> modified_base
<222> (10)
<223> B-L-deoxy nucleoside-G

<220> 
<221> modified_base
<222> (11)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (12)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (13)
<223> B-L-deoxy nucleoside-C

<220> 
<221> modified_base
<222> (14)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (15)
<223> B-L-deoxy nucleoside-C

<220> 
<221> modified_base
<222> (16)
<223> B-L-deoxy nucleoside-T

<220> 
<221> modified_base
<222> (17)
<223> B-L-deoxy nucleoside-G

<220> 
<221> modified_base
<222> (18)
<223> B-L-deoxy nucleoside-T

<400> 57
nnnnnnnnnn nnnnnnnn                                               18    


<210> 58
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 58
ctatctgacg t                                                      11    


<210> 59
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 59
ctatctgacg                                                        10    


<210> 60
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 60
ctatctgacg                                                        10    


<210> 61
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 61
ctatctagcg t                                                      11    


<210> 62
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 62
ctatctagcg                                                        10    


<210> 63
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 63
ctatctagcg                                                        10    


<210> 64
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<400> 64
ctatctaacg ttctctgt                                               18    


<210> 65
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<400> 65
ctatctagcg ttctctgt                                               18    


<210> 66
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<400> 66
ctatctaucg ttctctgt                                               18    


<210> 67
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<400> 67
ctatctaacn ttctctgt                                               18    


<210> 68
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<400> 68
ctatctagcn ttctctgt                                               18    


<210> 69
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<400> 69
ctatctaucn ttctctgt                                               18    


<210> 70
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 70
ctatctagcg t                                                      11    


<210> 71
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 71
ctatctagcg                                                        10    


<210> 72
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 72
ctatctagcg                                                        10    


<210> 73
<211> 15
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 73
tcctggaggg gaagt                                                  15    


<210> 74
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)
<223> 2'-OMe

<400> 74
ctatctgacg ttctctgt                                               18    


<210> 75
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<220> 
<221> modified_base
<222> (11)..(12)
<223> 2'-OMe

<400> 75
ctatctgacn uuctctgt                                               18    


<210> 76
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (8)
<223> 3'-OMe-G

<400> 76
cctactancg ttctcatc                                               18    


<210> 77
<211> 19
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> 3'-OMe-U

<400> 77
tccatgacgn tcctgatgc                                              19    


<210> 78
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 78
cgttctctgt                                                        10    


<210> 79
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 79
acgttctctg t                                                      11    


<210> 80
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)
<223> dU

<400> 80
ctatctnacg ttctctgt                                               18    


<210> 81
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (8)
<223> dU

<400> 81
ctatctgncg ttctctgt                                               18    


<210> 82
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 82
ctatctgacg                                                        10    


<210> 83
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 83
ctatctgacg t                                                      11    


<210> 84
<211> 10
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 84
cgttctctgt                                                        10    


<210> 85
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<400> 85
acgttctctg t                                                      11    


<210> 86
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<400> 86
tctgacgttc t                                                      11    


<210> 87
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-dG

<400> 87
tctgacnttc t                                                      11    


<210> 88
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> araG

<400> 88
tctgacnttc t                                                      11    


<210> 89
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (6)..(7)
<223> 2'-OMe

<400> 89
tctctgacgt t                                                      11    


<210> 90
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-dG

<400> 90
tctgacnttc t                                                      11    


<210> 91
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (11)..(12)
<223> 2'-OMe

<400> 91
ctatctgtcg uuctctgt                                               18    


<210> 92
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<220> 
<221> modified_base
<222> (11)..(12)
<223> 2'-OMe

<400> 92
ctatctgtcn uuctctgt                                               18    


<210> 93
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<400> 93
tctgucgttc t                                                      11    


<210> 94
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-dG

<400> 94
tctgucnttc t                                                      11    


<210> 95
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> araG

<400> 95
tctgacnttc t                                                      11    


<210> 96
<211> 9
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-dG

<400> 96
tctgacntt                                                         9     


<210> 97
<211> 11
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (4)..(5)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (7)
<223> 7-deaza-dG

<400> 97
tctgacnttc t                                                      11    


<210> 98
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<220> 
<221> modified_base
<222> (15)..(18)
<223> 2'-OMe

<400> 98
ctatctgacn ttctcugu                                               18    


<210> 99
<211> 18
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (7)..(8)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (10)
<223> 7-deaza-dG

<220> 
<221> modified_base
<222> (15)..(18)
<223> 2'-OMe

<400> 99
ctatctgucn ttctcugu                                               18    


<210> 100
<211> 9
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (1)..(3)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (5)
<223> 7-deaza-dG

<400> 100
ugucnttct                                                         9     


<210> 101
<211> 9
<212> DNA
<213> Artificial Sequence

<220> 
<223> Description of Combined DNA/RNA Molecule:
      Synthetic oligonucleotide

<220> 
<223> Description of Artificial Sequence: Synthetic
      oligonucleotide

<220> 
<221> modified_base
<222> (1)..(3)
<223> 2'-OMe

<220> 
<221> modified_base
<222> (5)
<223> 7-deaza-dG

<400> 101
ugacnttct                                                         9     

