
                                SEQUENCE LISTING

<110> Merck & Co., Inc.
      Bowman, Keith A.
      Guare, James P.
      Hartman, George D.
      Parmar, Rubina G.
      Vargeese, Chandra
      Wang, Weimin
      Zhang, Ye

<120> NOVEL LIPID NANOPARTICLES AND NOVEL
  COMPONENTS FOR DELIVERY OF NUCLEIC ACIDS
  

<130> MRL-MIS-00004

<150> 61/189,295          
<151> 2008-08-18  

<160> 2

<170> FastSEQ for Windows Version 4.0

<210> 1
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<220> 
<221> misc_feature   
<222> (1)...(4)
<223> 2'-fluoro

<220> 
<221> misc_feature   
<222> (5)...(6)
<223> 2'-deoxy

<220> 
<221> misc_feature   
<222> (7)...(7)
<223> 2'-fluoro

<220> 
<221> misc_feature   
<222> (8)...(9)
<223> 2'-deoxy


<220> 
<221> misc_feature   
<222> (10)...(14)
<223> 2'-fluoro


<220> 
<221> misc_feature   
<222> (15)...(18)
<223> 2'-deoxy


<220> 
<221> misc_feature   
<222> (19)...(19)
<223> 2'-fluoro


<220> 
<221> misc_feature   
<222> (20)...(21)
<223> 2'-deoxy

<400> 1
cuuuaacaau uccugaaaut t                                           21

<210> 2
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<223> Enzymatic Nucleic Acid

<220> 
<221> misc_feature   
<222> (1)...(6)
<223> 2'-o-methyl

<220> 
<221> misc_feature   
<222> (7)...(8)
<223> 2'-fluoro

<220> 
<221> misc_feature   
<222> (9)...(9)
<223> 2'-o-methyl

<220> 
<221> misc_feature   
<222> (10)...(11)
<223> 2'-fluoro


<220> 
<221> misc_feature   
<222> (12)...(17)
<223> 2'-o-methyl


<220> 
<221> misc_feature   
<222> (18)...(18)
<223> 2'-fluoro


<220> 
<221> misc_feature   
<222> (19)...(21)
<223> Ribose

<400> 2
uugaaauugu uaaggacuuu a                                           21
