                               SEQUENCE LISTING

<110> NEKTAR THERAPEUTICS

<120> CONJUGATES OF SMALL-INTERFERING NUCLEIC ACIDS

<130> SHE0205.PCT

<140> 
<141> 

<150> 61/153,636
<151> 2009-02-18

<150> 61/198,935
<151> 2008-11-12

<150> 60/189,528
<151> 2008-08-19

<160> 194   

<170> PatentIn version 3.2

<210> 1
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 1
cuccuuuugu uucugcuaac gtt                                             23


<210> 2
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 2
cguuagcaga aacaaaagga gtt                                             23


<210> 3
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 3
cuccuuuugu uucugcuaac gtt                                             23


<210> 4
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 4
cguuagcaga aacaaaagga gtt                                             23


<210> 5
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 5
cuccuuuugu uucugcuaac gtt                                             23


<210> 6
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 6
cguuagcaga aacaaaagga gtt                                             23


<210> 7
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 7
cucauuuucu uugugcucac gtt                                             23


<210> 8
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 8
cgugagcaca aagaaaauga gtt                                             23


<210> 9
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 9
cuccuuuugu uucugcuaac gtt                                             23


<210> 10
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 10
cguuagcaga aacaaaagga gtt                                             23


<210> 11
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 11
cucauuuucu uugugcucac gtt                                             23


<210> 12
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 12
cgugagcaca aagaaaauga gtt                                             23


<210> 13
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 13
cuccuuuugu uucugcuaac g                                               21


<210> 14
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 14
cguuagcaga aacaaaagga g                                               21


<210> 15
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 15
cucauuuucu uugugcucac g                                               21


<210> 16
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 16
cgugagcaca aagaaaauga g                                               21


<210> 17
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 17
ttcuccuuuu guuucugcua acg                                             23


<210> 18
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 18
ttcguuagca gaaacaaaag gag                                             23


<210> 19
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 19
ttcucauuuu cuuugugcuc acg                                             23


<210> 20
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 20
ttcgugagca caaagaaaau gag                                             23


<210> 21
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 21
ucuugaugua cuccccucgu u                                               21


<210> 22
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 22
cgaggggagu acaucaagau u                                               21


<210> 23
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 23
ucuugaugua cuccccucgu u                                               21


<210> 24
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 24
cgaggggagu acaucaagac c                                               21


<210> 25
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 25
cuugauguac uccccucgu                                                  19


<210> 26
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 26
gaggggagua caucaagac                                                  19


<210> 27
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 27
ucuugaugua cuccccucgt t                                               21


<210> 28
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 28
cgaggggagu acaucaagac c                                               21


<210> 29
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 29
ucuugaugua cuccccucgu u                                               21


<210> 30
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 30
cgaggggagu acaucaagau u                                               21


<210> 31
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 31
ucuugaugua cuccccucgt t                                               21


<210> 32
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 32
cgaggggagu acaucaagat t                                               21


<210> 33
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 33
acuugaugua cuccccucct t                                               21


<210> 34
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 34
ggaggggagu acaucaagut t                                               21


<210> 35
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 35
aguugaugua cuccccugct t                                               21


<210> 36
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 36
gcaggggagu acaucaacut t                                               21


<210> 37
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 37
ucuugaugua cuccccucgu u                                               21


<210> 38
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 38
cgaggggagu acaucaagau u                                               21


<210> 39
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 39
ucuugaugua cuccccucgu u                                               21


<210> 40
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 40
cgaggggagu acaucaagac c                                               21


<210> 41
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 41
ucuugaugua cuccccucgt t                                               21


<210> 42
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 42
cgaggggagu acaucaagac c                                               21


<210> 43
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 43
ucuugaugua cuccccucgt t                                               21


<210> 44
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 44
cgaggggagu acaucaagat t                                               21


<210> 45
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 45
cuugauguac uccccucgu                                                  19


<210> 46
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 46
gaggggagua caucaagac                                                  19


<210> 47
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 47
acuugaugua cuccccucct t                                               21


<210> 48
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 48
ggaggggagu acaucaagut t                                               21


<210> 49
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 49
aguugaugua cuccccugct t                                               21


<210> 50
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 50
gcaggggagu acaucaacut t                                               21


<210> 51
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 51
cuccuuuugu uucugcuaac gtt                                             23


<210> 52
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 52
cguuagcaga aacaaaagga gtt                                             23


<210> 53
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 53
uccuuuuguu ucugcuaac                                                  19


<210> 54
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 54
guuagcagaa acaaaagga                                                  19


<210> 55
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 55
uccuuuucuu ucugcuaac                                                  19


<210> 56
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 56
guuagcagaa agaaaagga                                                  19


<210> 57
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 57
uccuuuucuu ugugcuaac                                                  19


<210> 58
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 58
guuagcacaa agaaaagga                                                  19


<210> 59
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 59
uccuuuucuu ugugguaac                                                  19


<210> 60
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 60
guuaccacaa agaaaagga                                                  19


<210> 61
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 61
uccuauucuu ugugguaac                                                  19


<210> 62
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 62
guuaccacaa agaauagga                                                  19


<210> 63
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 63
cuccuuuugu uucugcuaac gtt                                             23


<210> 64
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 64
cguuagcaga aacaaaagga gtt                                             23


<210> 65
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (1)
<223> /note="NH2-modified"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 65
cuccuuuugu uucugcuaac gtt                                             23


<210> 66
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (1)
<223> /note="NH2-modified"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 66
cguuagcaga aacaaaagga gtt                                             23


<210> 67
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 67
cuccuuuugu uucugcuaac gtt                                             23


<210> 68
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 68
cguuagcaga aacaaaagga gtt                                             23


<210> 69
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 69
ttcguuagca gaaacaaaag gag                                             23


<210> 70
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 70
cuccuuuugu uucugcuaac gtt                                             23


<210> 71
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 71
cguuagcaga aacaaaagga gtt                                             23


<210> 72
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (1)
<223> /note="NH2-modified"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 72
cuccuuuugu uucugcuaac gtt                                             23


<210> 73
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 73
cuccuuuugu uucugcuaac gtt                                             23


<210> 74
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 74
cuccuuuugu uucugcuaac gtt                                             23


<210> 75
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 75
cuccuuuugu uucugcuaac gtt                                             23


<210> 76
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 76
ttcuccuuuu guuucugcua acg                                             23


<210> 77
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> misc_feature
<222> (1)
<223> /note="NH2-modified"

<220>
<221> misc_feature
<222> (23)
<223> /note="NH2-modified"

<400> 77
cguuagcaga aacaaaagga gtt                                             23


<210> 78
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 78
cuccuuuugu uucugcuaac gtt                                             23


<210> 79
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 79
cguuagcaga aacaaaagga gtt                                             23


<210> 80
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 80
cuccuuuugu uucugcuaac g                                               21


<210> 81
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 81
cuccuuuucu uugugcuaac g                                               21


<210> 82
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 82
cguuagcaca aacaaaagga g                                               21


<210> 83
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (3)..(19)
<223> 2'-O-methyl modified RNA

<400> 83
cuccuuuugu uucugcuaac g                                               21


<210> 84
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (3)..(19)
<223> 2'-O-methyl modified RNA

<400> 84
cguuagcaga aacaaaagga g                                               21


<210> 85
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (5)..(17)
<223> 2'-O-methyl modified RNA

<400> 85
cuccuuuugu uucugcuaac g                                               21


<210> 86
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (5)..(17)
<223> 2'-O-methyl modified RNA

<400> 86
cguuagcaga aacaaaagga g                                               21


<210> 87
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O-methyl modified RNA

<400> 87
cuccuuuugu uucugcuaac g                                               21


<210> 88
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O-methyl modified RNA

<400> 88
cguuagcaga aacaaaagga g                                               21


<210> 89
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 89
cuccuuuugu uucugcuaac g                                               21


<210> 90
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 90
cguuagcaga aacaaaagga g                                               21


<210> 91
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 91
cuccuuuugu uucugcuaac g                                               21


<210> 92
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 92
cguuagcaga aacaaaagga g                                               21


<210> 93
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O-methyl modified RNA

<400> 93
cuccuuuugu uucugcuaac g                                               21


<210> 94
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O-methyl modified RNA

<400> 94
cguuagcaga aacaaaagga g                                               21


<210> 95
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O-methyl modified RNA

<400> 95
cuccuuuugu uucugcuaac g                                               21


<210> 96
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O-methyl modified RNA

<400> 96
cguuagcaga aacaaaagga g                                               21


<210> 97
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (8)..(13)
<223> 2'-O-methyl modified RNA

<400> 97
cuccuuuugu uucugcuaac g                                               21


<210> 98
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (6)..(10)
<223> 2'-O-methyl modified RNA

<220>
<221> modified_base
<222> (16)..(21)
<223> 2'-O-methyl modified RNA

<400> 98
cuccuuuugu uucugcuaac g                                               21


<210> 99
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(11)
<223> 2'-O-methyl modified RNA

<220>
<221> modified_base
<222> (17)..(21)
<223> 2'-O-methyl modified RNA

<400> 99
cguuagcaga aacaaaagga g                                               21


<210> 100
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O-methyl modified RNA

<400> 100
cuccuuuugu uucugcuaac g                                               21


<210> 101
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 101
cuccuuuugu uucugcuaac g                                               21


<210> 102
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 102
cguuagcaga aacaaaagga g                                               21


<210> 103
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 103
cuccuuuugu uucugcuaac g                                               21


<210> 104
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O-methyl modified RNA

<400> 104
cguuagcaga aacaaaagga g                                               21


<210> 105
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O-methyl modified RNA

<400> 105
cuccuuuugu uucugcuaac g                                               21


<210> 106
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O-methyl modified RNA

<400> 106
cguuagcaga aacaaaagga g                                               21


<210> 107
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O-methyl modified RNA

<400> 107
cuccuuuugu uucugcuaac g                                               21


<210> 108
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O-methyl modified RNA

<400> 108
cguuagcaga aacaaaagga g                                               21


<210> 109
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (5)..(10)
<223> 2'-O-methyl modified RNA

<220>
<221> modified_base
<222> (16)..(21)
<223> 2'-O-methyl modified RNA

<400> 109
cuccuuuugu uucugcuaac g                                               21


<210> 110
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(11)
<223> 2'-O-methyl modified RNA

<220>
<221> modified_base
<222> (18)..(21)
<223> 2'-O-methyl modified RNA

<400> 110
cguuagcaga aacaaaagga g                                               21


<210> 111
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 111
cuccuuuugu uucugcuaac g                                               21


<210> 112
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 112
cguuagcaga aacaaaagga g                                               21


<210> 113
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 113
cuccuuuugu uucugcuaac g                                               21


<210> 114
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 114
cguuagcaga aacaaaagga g                                               21


<210> 115
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 115
cuccuuuugu uucugcuaac g                                               21


<210> 116
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 116
cguuagcaga aacaaaagga g                                               21


<210> 117
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 117
cuccuuuugu uucugcuaac g                                               21


<210> 118
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 118
cguuagcaga aacaaaagga g                                               21


<210> 119
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 119
cuccuuuugu uucugcuaac g                                               21


<210> 120
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 120
cguuagcaga aacaaaagga g                                               21


<210> 121
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 121
cucauuuucu uugugcucac g                                               21


<210> 122
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 122
cgugagcaca aagaaaauga g                                               21


<210> 123
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 123
cuccuuuugu uucugcuaac g                                               21


<210> 124
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 124
cguuagcaga aacaaaagga g                                               21


<210> 125
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (3)..(19)
<223> 2'-O methyl ribonucleotide

<400> 125
cuccuuuugu uucugcuaac g                                               21


<210> 126
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (3)..(19)
<223> 2'-O methyl ribonucleotide

<400> 126
cguuagcaga aacaaaagga g                                               21


<210> 127
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (5)..(17)
<223> 2'-O methyl ribonucleotide

<400> 127
cuccuuuugu uucugcuaac g                                               21


<210> 128
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (5)..(17)
<223> 2'-O methyl ribonucleotide

<400> 128
cguuagcaga aacaaaagga g                                               21


<210> 129
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O methyl ribonucleotide

<400> 129
cuccuuuugu uucugcuaac g                                               21


<210> 130
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O methyl ribonucleotide

<400> 130
cguuagcaga aacaaaagga g                                               21


<210> 131
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 131
cuccuuuugu uucugcuaac g                                               21


<210> 132
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 132
cguuagcaga aacaaaagga g                                               21


<210> 133
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 133
cuccuuuugu uucugcuaac g                                               21


<210> 134
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 134
cguuagcaga aacaaaagga g                                               21


<210> 135
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O methyl ribonucleotide

<400> 135
cuccuuuugu uucugcuaac g                                               21


<210> 136
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(11)
<223> 2'-O methyl ribonucleotide

<400> 136
cguuagcaga aacaaaagga g                                               21


<210> 137
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O methyl ribonucleotide

<400> 137
cuccuuuugu uucugcuaac g                                               21


<210> 138
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (11)..(21)
<223> 2'-O methyl ribonucleotide

<400> 138
cguuagcaga aacaaaagga g                                               21


<210> 139
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (8)..(13)
<223> 2'-O methyl ribonucleotide

<400> 139
cuccuuuugu uucugcuaac g                                               21


<210> 140
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 140
cguuagcaga aacaaaagga g                                               21


<210> 141
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (6)..(10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)..(21)
<223> 2'-O methyl ribonucleotide

<400> 141
cuccuuuugu uucugcuaac g                                               21


<210> 142
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)..(21)
<223> 2'-O methyl ribonucleotide

<400> 142
cguuagcaga aacaaaagga g                                               21


<210> 143
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (7)..(15)
<223> 2'-O methyl ribonucleotide

<400> 143
cuccuuuugu uucugcuaac g                                               21


<210> 144
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)..(21)
<223> 2'-O methyl ribonucleotide

<400> 144
cguuagcaga aacaaaagga g                                               21


<210> 145
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 145
cuccuuuugu uucugcuaac g                                               21


<210> 146
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 146
cguuagcaga aacaaaagga g                                               21


<210> 147
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 147
cuccuuuugu uucugcuaac g                                               21


<210> 148
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 148
cguuagcaga aacaaaagga g                                               21


<210> 149
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 149
cuccuuuugu uucugcuaac g                                               21


<210> 150
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 150
cguuagcaga aacaaaagga g                                               21


<210> 151
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 151
cuccuuuugu uucugcuaac g                                               21


<210> 152
<211> 21
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 152
cguuagcaga aacaaaagga g                                               21


<210> 153
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 153
ucuugaugua cuccccucgt t                                               21


<210> 154
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 154
cgaggggagu acaucaagat t                                               21


<210> 155
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 155
ucuugaugua cuccccucg                                                  19


<210> 156
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 156
cgaggggagu acaucaaga                                                  19


<210> 157
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 157
ucuugaugua cuccccucg                                                  19


<210> 158
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 158
cgaggggagu acaucaaga                                                  19


<210> 159
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 159
ucuugaugua cuccccucg                                                  19


<210> 160
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 160
cgaggggagu acaucaaga                                                  19


<210> 161
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 161
ucuugaugua cuccccucg                                                  19


<210> 162
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 162
cgaggggagu acaucaaga                                                  19


<210> 163
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 163
ucuugaugua cuccccucg                                                  19


<210> 164
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 164
cgaggggagu acaucaaga                                                  19


<210> 165
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 165
aauuccagug guucauucc                                                  19


<210> 166
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<400> 166
ggaaugaacc acuggaauu                                                  19


<210> 167
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 167
aauuccagug guucauucc                                                  19


<210> 168
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 168
ggaaugaacc acuggaauu                                                  19


<210> 169
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 169
aauuccagug guucauucc                                                  19


<210> 170
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 170
ggaaugaacc acuggaauu                                                  19


<210> 171
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 171
aauuccagug guucauucc                                                  19


<210> 172
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (20)
<223> 2'-O methyl ribonucleotide

<400> 172
ggaaugaacc acuggaauu                                                  19


<210> 173
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"


<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 173
aauuccagug guucauucc                                                  19


<210> 174
<211> 19
<212> RNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O methyl ribonucleotide

<220>
<221> modified_base
<222> (21)
<223> 2'-O methyl ribonucleotide

<400> 174
ggaaugaacc acuggaauu                                                  19


<210> 175
<211> 12
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      pA-loop"


<400> 175
aaaaaaaaaa aa                                                     12    


<210> 176
<211> 22
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence:  Synthetic
      primer"

<400> 176
caccgccaaa tttaactgca ga                                          22    


<210> 177
<211> 24
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 177
aagggtttga taagttctag ctgt                                        24    


<210> 178
<211> 31
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 178
tgcacagtat ccttttgaag accataaccc a                                31    


<210> 179
<211> 22
<212> DNA
<213> Artificial Sequence

<220> 
<222>
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 179
gtttgagacc ttcaacaccc ca                                          22    


<210> 180
<211> 21
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      primer"

<400> 180
gaccagaggc atacagggac a                                           21    


<210> 181
<211> 26
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      probe"

<400> 181
ccatgtacgt agccatccag gctgtg                                      26    


<210> 182
<211> 23
<212> DNA
<213> Artificial Sequence

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic 
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Artificial Sequence: Synthetic
      oligonucleotide"

<400> 182
ucuccuuttg tttctgcuaa cga                                         23    


<210> 183
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 183
acaacagacu uuaauguaa                                                    19


<210> 184
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 184
acaacagacu uuaauguaa                                                    19


<210> 185
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 185
acaacagacu uuaauguaa                                                    19


<210> 186
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 186
acaacagacu uuaauguaa                                                    19


<210> 187
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 187
acaacagacu uuaauguaa                                                    19


<210> 188
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O-methyl ribonucleotide

<400> 188
uuacauuaaa gucuguugu                                                    19


<210> 189
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O-methyl ribonucleotide

<400> 189
uuacauuaaa gucuguugu                                                    19


<210> 190
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O-methyl ribonucleotide

<400> 190
uuacauuaaa gucuguugu                                                    19


<210> 191
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (8)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (10)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (12)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (14)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (18)
<223> 2'-O-methyl ribonucleotide

<400> 191
acaacagacu uuaauguaa                                                    19


<210> 192
<211> 19
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (1)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (3)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (13)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (17)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-O-methyl ribonucleotide

<400> 192
uuacauuaaa gucuguugu                                                    19


<210> 193
<211> 21
<212> DNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220> 
<221> source
<223> /note="Description of Combined DNA/RNA Molecule: Synthetic
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (5)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (11)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (20)..(21)
<223> 2'-O-methyl modified RNA

<400> 193
acaacagact utaatgtaau u                                                 21


<210> 194
<211> 21
<212> RNA
<213> Artificial Sequence

<220>
<221> source
<223> /note="Description of Artificial Sequence: Synthetic 
      oligonucleotide"

<220>
<221> modified_base
<222> (2)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (4)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (6)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (7)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (9)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (11)..(12)
<223> 2'-O-methyl modified RNA

<220>
<221> modified_base
<222> (13)..(14)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (15)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (16)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (17)..(18)
<223> 2'-O-methyl ribonucleotide

<220>
<221> modified_base
<222> (19)
<223> 2'-fluoro-nucleotide

<220>
<221> modified_base
<222> (20)..(21)
<223> 2'-O-methyl modified RNA

<400> 194
uuacauuaaa gucuguuguu u                                                 21
