                                 SEQUENCE LISTING
                       

      <110> Tang, Y. Tom
        Yang, Yonghong
        Wang, Zhiwei
        Weng, Gezhi
        Ma, Yunqing

      <120> Novel Nucleic Acids and Secreted Polypeptides



      <130> 806CIP/PCT

      <140> To Be Assigned
      <141> To Be Assigned
	
      <150> US 60/311,261
      <151> 2001-08-09

      <150> US 09/488,725
      <151> 2000-01-21

      <150> US 09/552,317
      <151> 2000-04-25

      <150> US 09/491,404
      <151> 2000-01-25

      <150> US 09/496,914
      <151> 2000-02-03

      <150> US 09/560,875
      <151> 2000-04-27

      <150> US 09/515,126
      <151> 2000-02-28

      <150> US 09/577,409
      <151> 2000-05-18

      <150> US 09/519,705
      <151> 2000-03-07

      <150> US 09/574,454
      <151> 2000-05-19

      <150> US 09/540,217
      <151> 2000-03-31

      <150> US 09/649,167
      <151> 2000-08-23

      <150> US 09/552,929
      <151> 2000-04-18

      <150> US 09/770,160
      <151> 2001-01-26

      <150> US 09/577,408
      <151> 2000-05-18

      <160> 2986

      <170> pt_FL_genes Version 5.0




      <210> 1
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 1
  atg ccc gct gtc agc agg aag cag tta aga tca atc ttc atc ctt atc      48
  Met Pro Ala Val Ser Arg Lys Gln Leu Arg Ser Ile Phe Ile Leu Ile
    1               5                  10                  15

 cca atc ctt att cta atg gca gtt aga agt act tct tta gag tgg gga       96
 Pro Ile Leu Ile Leu Met Ala Val Arg Ser Thr Ser Leu Glu Trp Gly
              20                  25                  30

 atg aga cag cca agt aaa aag agg tcc ctg gag aaa ctc cga ctg gtc      144
 Met Arg Gln Pro Ser Lys Lys Arg Ser Leu Glu Lys Leu Arg Leu Val
          35                  40                  45

 cgc gca ctg ggg tgg agc ctc ggg agg ttt acc cgt ttg cag agg gag      192
 Arg Ala Leu Gly Trp Ser Leu Gly Arg Phe Thr Arg Leu Gln Arg Glu
      50                  55                  60

 gag ctt gtc ctc tcc cgt acc agg gtg gta acc tgg gga ttc aat ctg      240
 Glu Leu Val Leu Ser Arg Thr Arg Val Val Thr Trp Gly Phe Asn Leu
  65                  70                  75                  80

 tcg tct ggt tgt ata aaa gct ttc cca cac aag agg act gat gtt gta      288
 Ser Ser Gly Cys Ile Lys Ala Phe Pro His Lys Arg Thr Asp Val Val
                  85                  90                  95

 aca gta gct cat cat gcc acc gtg tat ttt cac cag gaa aag aaa gct      336
 Thr Val Ala His His Ala Thr Val Tyr Phe His Gln Glu Lys Lys Ala
             100                 105                 110

 ttt cat ggt tca ctg act gag gac atg aag ccc ttc aca atc tag          381
 Phe His Gly Ser Leu Thr Glu Asp Met Lys Pro Phe Thr Ile 
         115                 120                 125





      <210> 2
      <211> 585
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(585)

      <400> 2
  atg gag acc tgg tct ggc ccc gcc gga gct cag ggc tat gcc ctc atg      48
  Met Glu Thr Trp Ser Gly Pro Ala Gly Ala Gln Gly Tyr Ala Leu Met
    1               5                  10                  15

 tgc gta ctg atg tgg ctg gag agt gag gga gta cgc aaa ggc cct tct       96
 Cys Val Leu Met Trp Leu Glu Ser Glu Gly Val Arg Lys Gly Pro Ser
              20                  25                  30

 ggg tca tgc ctg cgg agc tgc cgc ctt acc ttt ggg gga gct gaa aag      144
 Gly Ser Cys Leu Arg Ser Cys Arg Leu Thr Phe Gly Gly Ala Glu Lys
          35                  40                  45

 gct gca tgg aag agt gac tta gga acc agc ctg ggc ata att agg gca      192
 Ala Ala Trp Lys Ser Asp Leu Gly Thr Ser Leu Gly Ile Ile Arg Ala
      50                  55                  60

 cac agt gag gac cgc aca gag cag gat cag cga gtt gtg tgg ttt ggt      240
 His Ser Glu Asp Arg Thr Glu Gln Asp Gln Arg Val Val Trp Phe Gly
  65                  70                  75                  80

 gtg tct gct gta ggt ggt ggt gac ggt agg cag gag aca gat ttt gga      288
 Val Ser Ala Val Gly Gly Gly Asp Gly Arg Gln Glu Thr Asp Phe Gly
                  85                  90                  95

 ctt gat tct tat aaa gag ctg gta atg ggc tct aag gcc ttt cag cag      336
 Leu Asp Ser Tyr Lys Glu Leu Val Met Gly Ser Lys Ala Phe Gln Gln
             100                 105                 110

 aga gat att cct agt ggc tgc gaa gtt gct tgc tgt gac ccc gcg cgg      384
 Arg Asp Ile Pro Ser Gly Cys Glu Val Ala Cys Cys Asp Pro Ala Arg
         115                 120                 125

 cta tgg cag gaa cag cct aga cac atg gac agt gaa gag tca ctc aga      432
 Leu Trp Gln Glu Gln Pro Arg His Met Asp Ser Glu Glu Ser Leu Arg
     130                 135                 140

 att cgg acg cac gaa tgc ttg ctt gct ttt cag atc cag aaa agt ggt      480
 Ile Arg Thr His Glu Cys Leu Leu Ala Phe Gln Ile Gln Lys Ser Gly
 145                 150                 155                 160

 cac ttc ttt cat cga aac tcc ttg tcc cct cgg agt ctg gtg tat gaa      528
 His Phe Phe His Arg Asn Ser Leu Ser Pro Arg Ser Leu Val Tyr Glu
                 165                 170                 175

 agt gaa ttc tcc acc atc gaa cct tct ttg gac atg tat gat gag aac      576
 Ser Glu Phe Ser Thr Ile Glu Pro Ser Leu Asp Met Tyr Asp Glu Asn
             180                 185                 190

 aaa acc tga                                                          585
 Lys Thr 






      <210> 3
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 3
  atg gct ggg agt atg ctt ttg aag gca ctg ctg gac gtt acc ctg ctg      48
  Met Ala Gly Ser Met Leu Leu Lys Ala Leu Leu Asp Val Thr Leu Leu
    1               5                  10                  15

 agc act gct tcc atc aca ggt gca ctg ggc ctc aac act tct gcc att       96
 Ser Thr Ala Ser Ile Thr Gly Ala Leu Gly Leu Asn Thr Ser Ala Ile
              20                  25                  30

 tcc cca ttt gtc tcc tcc atg gac act gtc aac aat ggt ctg tca aca      144
 Ser Pro Phe Val Ser Ser Met Asp Thr Val Asn Asn Gly Leu Ser Thr
          35                  40                  45

 cct gct ctg tgc caa agc cag gga gta ggc tgg ggg gat acg gaa gag      192
 Pro Ala Leu Cys Gln Ser Gln Gly Val Gly Trp Gly Asp Thr Glu Glu
      50                  55                  60

 aat atc ttt ctc ctt gat gcc tgc tgt gcc aac agc ccc ctt taa          237
 Asn Ile Phe Leu Leu Asp Ala Cys Cys Ala Asn Ser Pro Leu 
  65                  70                  75





      <210> 4
      <211> 765
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(765)

      <400> 4
  atg agc ctg ctg ccc atc tac act cag ctc ctg tct ttg tct tcc tca      48
  Met Ser Leu Leu Pro Ile Tyr Thr Gln Leu Leu Ser Leu Ser Ser Ser
    1               5                  10                  15

 gcc agt ggt gag gtg atc tat agt ggt tct ggg aca gtg tat tat ggc       96
 Ala Ser Gly Glu Val Ile Tyr Ser Gly Ser Gly Thr Val Tyr Tyr Gly
              20                  25                  30

 aga atc agg tcc tgg gag gag ggc atc ttg aat gtg cca ggg ctg gtt      144
 Arg Ile Arg Ser Trp Glu Glu Gly Ile Leu Asn Val Pro Gly Leu Val
          35                  40                  45

 tcc agc ctc tcc cat cct gct aat ggg tgc acg ctt tcc atg aat tgc      192
 Ser Ser Leu Ser His Pro Ala Asn Gly Cys Thr Leu Ser Met Asn Cys
      50                  55                  60

 tgt gtg atg ttc aca cgg agg tac ggt gtc aag ggg ggc ctg gat gga      240
 Cys Val Met Phe Thr Arg Arg Tyr Gly Val Lys Gly Gly Leu Asp Gly
  65                  70                  75                  80

 aat ggc agc tac cag gtg gaa agg ccg tgt gga ctg act ggt ttg gaa      288
 Asn Gly Ser Tyr Gln Val Glu Arg Pro Cys Gly Leu Thr Gly Leu Glu
                  85                  90                  95

 aac cct gag ctt aat gca gga ctg aac tct agt gtc tca gat gct aca      336
 Asn Pro Glu Leu Asn Ala Gly Leu Asn Ser Ser Val Ser Asp Ala Thr
             100                 105                 110

 gaa att caa gac aag atc aag ttc tta gct tct ctt tgg ctt ctc tgt      384
 Glu Ile Gln Asp Lys Ile Lys Phe Leu Ala Ser Leu Trp Leu Leu Cys
         115                 120                 125

 ggt tct cct agt tgc tgt tgg ggg ctc ctg ctc ctt tct ttc cac ccc      432
 Gly Ser Pro Ser Cys Cys Trp Gly Leu Leu Leu Leu Ser Phe His Pro
     130                 135                 140

 atg cag gct gat gca gtc aca cag ggc agc tac agc ttc agt ttt gtc      480
 Met Gln Ala Asp Ala Val Thr Gln Gly Ser Tyr Ser Phe Ser Phe Val
 145                 150                 155                 160

 tgg ctg ttt atc agc ttt gga gtg agt tgt aac aga att cct tcc tgc      528
 Trp Leu Phe Ile Ser Phe Gly Val Ser Cys Asn Arg Ile Pro Ser Cys
                 165                 170                 175

 act gtg gac tgc tcc tca gct gat att tgg caa cat ccc tgg cct cta      576
 Thr Val Asp Cys Ser Ser Ala Asp Ile Trp Gln His Pro Trp Pro Leu
             180                 185                 190

 ctc aat ggc tat tgt ttt cac aac atc tac agc caa tat gaa ctg ctg      624
 Leu Asn Gly Tyr Cys Phe His Asn Ile Tyr Ser Gln Tyr Glu Leu Leu
         195                 200                 205

 ctc tat ggt atg tac aaa cgt gtg cac tat tta aac act gtt gag aaa      672
 Leu Tyr Gly Met Tyr Lys Arg Val His Tyr Leu Asn Thr Val Glu Lys
     210                 215                 220

 aag gac ctc ctt gga aca aag gca gat gag tac ctt tcc tgg gtg gca      720
 Lys Asp Leu Leu Gly Thr Lys Ala Asp Glu Tyr Leu Ser Trp Val Ala
 225                 230                 235                 240

 ctg gac aca acg atg ctt ggc ctc tgg tct gtg gcc cag agg tag          765
 Leu Asp Thr Thr Met Leu Gly Leu Trp Ser Val Ala Gln Arg 
                 245                 250





      <210> 5
      <211> 339
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(339)

      <400> 5
  atg cct aca tcc tct tgc ctc ttc ctc atg cct tgc ctc ctg gcc agt      48
  Met Pro Thr Ser Ser Cys Leu Phe Leu Met Pro Cys Leu Leu Ala Ser
    1               5                  10                  15

 ggc cta gcg cta ccc tgt tgt cct aaa gag ttt ctg ctg ctg ctg cca       96
 Gly Leu Ala Leu Pro Cys Cys Pro Lys Glu Phe Leu Leu Leu Leu Pro
              20                  25                  30

 cta cca cca cca cca cac tgc tat atg ttg agg agt cct gta cac tgt      144
 Leu Pro Pro Pro Pro His Cys Tyr Met Leu Arg Ser Pro Val His Cys
          35                  40                  45

 gcc act gac aag gag ggg ata tta gca cct aag cat ttc cag gca gca      192
 Ala Thr Asp Lys Glu Gly Ile Leu Ala Pro Lys His Phe Gln Ala Ala
      50                  55                  60

 gct ggg gaa gcc aga acc tcc aca gac aga tct ggt gca cag gca caa      240
 Ala Gly Glu Ala Arg Thr Ser Thr Asp Arg Ser Gly Ala Gln Ala Gln
  65                  70                  75                  80

 agg tca gtt act cct tgt cag tgg cac agt gta cag gac tcc tca aca      288
 Arg Ser Val Thr Pro Cys Gln Trp His Ser Val Gln Asp Ser Ser Thr
                  85                  90                  95

 tat agc agt gtg gtg gtg gtg gta gtg gca gca gca gca gaa act ctt      336
 Tyr Ser Ser Val Val Val Val Val Val Ala Ala Ala Ala Glu Thr Leu
             100                 105                 110

 tag                                                                  339
 






      <210> 6
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 6
  atg ctg gcc tcc cct ccc ctc ttc tct ctt ctc tcc tcc ctc cct ctc      48
  Met Leu Ala Ser Pro Pro Leu Phe Ser Leu Leu Ser Ser Leu Pro Leu
    1               5                  10                  15

 ttc ctt cct tcc acc gtt gtg ggc aac aca gtc aat gat tca aat ggt       96
 Phe Leu Pro Ser Thr Val Val Gly Asn Thr Val Asn Asp Ser Asn Gly
              20                  25                  30

 gta aaa ggg gaa ata ata aaa aga att ata aaa ccc cag aac tgg aag      144
 Val Lys Gly Glu Ile Ile Lys Arg Ile Ile Lys Pro Gln Asn Trp Lys
          35                  40                  45

 gcc att tac gca aca agc act tat gga gca cct acg gcc cct gcc cca      192
 Ala Ile Tyr Ala Thr Ser Thr Tyr Gly Ala Pro Thr Ala Pro Ala Pro
      50                  55                  60

 ccc att gct gtc aac gag atg tct att ccc ctg gcc act gcc acc tct      240
 Pro Ile Ala Val Asn Glu Met Ser Ile Pro Leu Ala Thr Ala Thr Ser
  65                  70                  75                  80

 ggg acc cag gac ttg gcc ctc ctt cct gct ggt aac tgc tcc tgg tac      288
 Gly Thr Gln Asp Leu Ala Leu Leu Pro Ala Gly Asn Cys Ser Trp Tyr
                  85                  90                  95

 ccc tcc tcc aag gcc cct tga                                          309
 Pro Ser Ser Lys Ala Pro 
             100





      <210> 7
      <211> 1041
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1041)

      <400> 7
  atg tgg aac ggt atg ctg gtg ctg gtg gcc cag gca gga ggt gac act      48
  Met Trp Asn Gly Met Leu Val Leu Val Ala Gln Ala Gly Gly Asp Thr
    1               5                  10                  15

 ctc aaa gtg act ggt cac tac gta aaa tgt gtc ttt ctt ttg ttt gtt       96
 Leu Lys Val Thr Gly His Tyr Val Lys Cys Val Phe Leu Leu Phe Val
              20                  25                  30

 tcc cac ctg ctt tcc gag ccc ctt tct cgg aca gtt gac cac ggc atg      144
 Ser His Leu Leu Ser Glu Pro Leu Ser Arg Thr Val Asp His Gly Met
          35                  40                  45

 ttt gag aat ttg aac aca gcc ctc act cca aag ctc cag gcc agc cgc      192
 Phe Glu Asn Leu Asn Thr Ala Leu Thr Pro Lys Leu Gln Ala Ser Arg
      50                  55                  60

 tcc ttc ccc cac ttg tcc aag ccc gtg gcc ccc ggc tct gcc ctc tgg      240
 Ser Phe Pro His Leu Ser Lys Pro Val Ala Pro Gly Ser Ala Leu Trp
  65                  70                  75                  80

 gct ctg gag gat aaa ggc ctg gcc aat tct cag ctg tgt ggg tcc tct      288
 Ala Leu Glu Asp Lys Gly Leu Ala Asn Ser Gln Leu Cys Gly Ser Ser
                  85                  90                  95

 gga tcc ttg gat ctg aca ctg gcc cag ggg cag caa agg ggc aaa ggg      336
 Gly Ser Leu Asp Leu Thr Leu Ala Gln Gly Gln Gln Arg Gly Lys Gly
             100                 105                 110

 act cca ggc cag ctc ttc tct gag cca cct tct ctc cgc agg agg gtc      384
 Thr Pro Gly Gln Leu Phe Ser Glu Pro Pro Ser Leu Arg Arg Arg Val
         115                 120                 125

 gtg cct gtg cac atc atg atg gca cat cct gaa aca gtg ata ggt cgg      432
 Val Pro Val His Ile Met Met Ala His Pro Glu Thr Val Ile Gly Arg
     130                 135                 140

 gtt ggc aga gcc ttc tcc cag gga acc ggc cac ctt gtt caa gaa aaa      480
 Val Gly Arg Ala Phe Ser Gln Gly Thr Gly His Leu Val Gln Glu Lys
 145                 150                 155                 160

 gaa cgt tct cct ctt gct gca aag agc ccc aga att agg atc acc ccc      528
 Glu Arg Ser Pro Leu Ala Ala Lys Ser Pro Arg Ile Arg Ile Thr Pro
                 165                 170                 175

 tta cag gat ctg ctg gtc aca gga aga cag cac aat agg ccc ctg gtg      576
 Leu Gln Asp Leu Leu Val Thr Gly Arg Gln His Asn Arg Pro Leu Val
             180                 185                 190

 gga gac cta aaa gtg ggt tgc agg aac cag tta agg ctg gat gaa cct      624
 Gly Asp Leu Lys Val Gly Cys Arg Asn Gln Leu Arg Leu Asp Glu Pro
         195                 200                 205

 gtg ggc tcc cag gac agc ttg ctg gag atc acc ttc cgc tcc gga gcc      672
 Val Gly Ser Gln Asp Ser Leu Leu Glu Ile Thr Phe Arg Ser Gly Ala
     210                 215                 220

 ctg ccc gtg ctc tgt gac ccc acg acc cct aag cca gag gac ctg cat      720
 Leu Pro Val Leu Cys Asp Pro Thr Thr Pro Lys Pro Glu Asp Leu His
 225                 230                 235                 240

 tcg ccg ccg ctg ggc gcg ggc ttg gct gac ttt gcc cac cct gcg ggc      768
 Ser Pro Pro Leu Gly Ala Gly Leu Ala Asp Phe Ala His Pro Ala Gly
                 245                 250                 255

 agc ccc tta ggt agg cgc gac tgc ttg gtg aag ctg gag tgc ttt cgc      816
 Ser Pro Leu Gly Arg Arg Asp Cys Leu Val Lys Leu Glu Cys Phe Arg
             260                 265                 270

 ttt ctt ccg ccc gag gac acc ccg ccc cca gcg cag ggc gag gcg ctc      864
 Phe Leu Pro Pro Glu Asp Thr Pro Pro Pro Ala Gln Gly Glu Ala Leu
         275                 280                 285

 ctg ggc ggt ctg gag ctc atc aag ttc cga gag tca ggc atc gcc tcg      912
 Leu Gly Gly Leu Glu Leu Ile Lys Phe Arg Glu Ser Gly Ile Ala Ser
     290                 295                 300

 gag tac gag tcc aac acg gac gag agc gag gag cgc gac tcg tgg tcc      960
 Glu Tyr Glu Ser Asn Thr Asp Glu Ser Glu Glu Arg Asp Ser Trp Ser
 305                 310                 315                 320

 cag gag gag ctg ccg cgc ctg ctg aat gtc ctg cag agg cag gaa ctg     1008
 Gln Glu Glu Leu Pro Arg Leu Leu Asn Val Leu Gln Arg Gln Glu Leu
                 325                 330                 335

 ggc gac ggc ctg gat gat gag atc gcc gtg tag                         1041
 Gly Asp Gly Leu Asp Asp Glu Ile Ala Val 
             340                 345





      <210> 8
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 8
  atg ctc tac ctg tat ata att att gtc tca gtt tta cag gta aaa gag      48
  Met Leu Tyr Leu Tyr Ile Ile Ile Val Ser Val Leu Gln Val Lys Glu
    1               5                  10                  15

 aga aaa atc tat gca aat cac aat gta agt cta gaa gtg att aaa att       96
 Arg Lys Ile Tyr Ala Asn His Asn Val Ser Leu Glu Val Ile Lys Ile
              20                  25                  30

 gat aaa aag caa agc aac tat gca aaa tat gga tat atg aac cag gac      144
 Asp Lys Lys Gln Ser Asn Tyr Ala Lys Tyr Gly Tyr Met Asn Gln Asp
          35                  40                  45

 gac ttg gga ctc tta ctg tct gga aag aat ggc att gtg tta gag gaa      192
 Asp Leu Gly Leu Leu Leu Ser Gly Lys Asn Gly Ile Val Leu Glu Glu
      50                  55                  60

 aaa taa                                                              198
 Lys 
  65





      <210> 9
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 9
  atg ctc ctg ctg tct cag acc ctc tgc cta ggg gag cag gtg ctg ctg      48
  Met Leu Leu Leu Ser Gln Thr Leu Cys Leu Gly Glu Gln Val Leu Leu
    1               5                  10                  15

 ggg gcc tgg ctg gta tgg ggg ccc agc cgg gac ccc agg ccc ctg ccg       96
 Gly Ala Trp Leu Val Trp Gly Pro Ser Arg Asp Pro Arg Pro Leu Pro
              20                  25                  30

 tat ctg tgc cat gac gag ccc tac aca ttt gac atc aac ctc tct gtt      144
 Tyr Leu Cys His Asp Glu Pro Tyr Thr Phe Asp Ile Asn Leu Ser Val
          35                  40                  45

 aac ctg aaa ggc cct gga aac aga ttg gga gag ccg atc ccc att tcc      192
 Asn Leu Lys Gly Pro Gly Asn Arg Leu Gly Glu Pro Ile Pro Ile Ser
      50                  55                  60

 aag gcc cat gag cac att ttt gga atg gtc ctt atg aac gac tgg agt      240
 Lys Ala His Glu His Ile Phe Gly Met Val Leu Met Asn Asp Trp Ser
  65                  70                  75                  80

 ggt aat tac tgg agc tct gtt cct gta aag atg acc ggg aag gag ctg      288
 Gly Asn Tyr Trp Ser Ser Val Pro Val Lys Met Thr Gly Lys Glu Leu
                  85                  90                  95

 ggg act tgg ggc aat ttc ata aaa gct gaa gat tgg tgc agg tca aaa      336
 Gly Thr Trp Gly Asn Phe Ile Lys Ala Glu Asp Trp Cys Arg Ser Lys
             100                 105                 110

 ggg gca gta atg gca tta ccg cga gcg gtg act cct acg cgc gca att      384
 Gly Ala Val Met Ala Leu Pro Arg Ala Val Thr Pro Thr Arg Ala Ile
         115                 120                 125

 aac gaa tcc acc atc ggg gca gct ggt gtc gat aac gaa gta tct tca      432
 Asn Glu Ser Thr Ile Gly Ala Ala Gly Val Asp Asn Glu Val Ser Ser
     130                 135                 140

 acc ggt tga                                                          441
 Thr Gly 
 145





      <210> 10
      <211> 156
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(156)

      <400> 10
  atg aga ctg gga aaa gga aac agg tct act gct tgg gct agc tct ttc      48
  Met Arg Leu Gly Lys Gly Asn Arg Ser Thr Ala Trp Ala Ser Ser Phe
    1               5                  10                  15

 agg acc cag ctg cct gtc ctg ctc ctc tcc ttc ttg agg ttc act ctc       96
 Arg Thr Gln Leu Pro Val Leu Leu Leu Ser Phe Leu Arg Phe Thr Leu
              20                  25                  30

 tgg gta ggc act gcc ctg agc aaa gcc aag aac cag aat gga tac aag      144
 Trp Val Gly Thr Ala Leu Ser Lys Ala Lys Asn Gln Asn Gly Tyr Lys
          35                  40                  45

 agc agg gaa taa                                                      156
 Ser Arg Glu 
      50





      <210> 11
      <211> 939
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(939)

      <400> 11
  atg ctt ctt gct cag ata agg aca gta atg tgg gtg tgc tgg att ttc      48
  Met Leu Leu Ala Gln Ile Arg Thr Val Met Trp Val Cys Trp Ile Phe
    1               5                  10                  15

 ata ccc act ctg cct ggg aag ctg act tct gtg ggg aca tta gta gct       96
 Ile Pro Thr Leu Pro Gly Lys Leu Thr Ser Val Gly Thr Leu Val Ala
              20                  25                  30

 cgc ttg tcc tct ggc ttc tgg cag aat ttg gct aat ggg atg cct atg      144
 Arg Leu Ser Ser Gly Phe Trp Gln Asn Leu Ala Asn Gly Met Pro Met
          35                  40                  45

 gag aag agc tct att tat gaa atg ttt gga aat gaa tgc tgt ttt tca      192
 Glu Lys Ser Ser Ile Tyr Glu Met Phe Gly Asn Glu Cys Cys Phe Ser
      50                  55                  60

 aca gga gaa gtg att aaa att act ggt ctc aaa gtt aag aag atc ata      240
 Thr Gly Glu Val Ile Lys Ile Thr Gly Leu Lys Val Lys Lys Ile Ile
  65                  70                  75                  80

 gct gaa att tgt gag cag att gaa ggt tgt gag tct cta cag cca ttt      288
 Ala Glu Ile Cys Glu Gln Ile Glu Gly Cys Glu Ser Leu Gln Pro Phe
                  85                  90                  95

 gaa ctg cct atg aat ttt cca ggg act ttt gtt aaa aga agc aag gaa      336
 Glu Leu Pro Met Asn Phe Pro Gly Thr Phe Val Lys Arg Ser Lys Glu
             100                 105                 110

 tgt ctt ttt aag att gtg gct gat aaa act cca tac ctt act atg gaa      384
 Cys Leu Phe Lys Ile Val Ala Asp Lys Thr Pro Tyr Leu Thr Met Glu
         115                 120                 125

 gaa atc aca agg acc att cat att gga cca agt aga cta ggg cat cct      432
 Glu Ile Thr Arg Thr Ile His Ile Gly Pro Ser Arg Leu Gly His Pro
     130                 135                 140

 tgc ttc tat cat cag aag gat ata aaa cta gag aac ctc atc ata aag      480
 Cys Phe Tyr His Gln Lys Asp Ile Lys Leu Glu Asn Leu Ile Ile Lys
 145                 150                 155                 160

 cag ggt gag caa atc atg ctc aac tca gtt gaa gag att gat gga gaa      528
 Gln Gly Glu Gln Ile Met Leu Asn Ser Val Glu Glu Ile Asp Gly Glu
                 165                 170                 175

 ata atg gtg agc tgt gca gta gca agg aat cat caa act cac tca ttt      576
 Ile Met Val Ser Cys Ala Val Ala Arg Asn His Gln Thr His Ser Phe
             180                 185                 190

 aat ttg cct ttg tca caa gaa gga gaa ttc tac gag tgt gaa gat gaa      624
 Asn Leu Pro Leu Ser Gln Glu Gly Glu Phe Tyr Glu Cys Glu Asp Glu
         195                 200                 205

 cgt att tac act cta aag gag att gtt gaa tgg aag att cct aag aac      672
 Arg Ile Tyr Thr Leu Lys Glu Ile Val Glu Trp Lys Ile Pro Lys Asn
     210                 215                 220

 aga aca aga act gta aac ctt aca gat ttt tca aat aag tgg gac tca      720
 Arg Thr Arg Thr Val Asn Leu Thr Asp Phe Ser Asn Lys Trp Asp Ser
 225                 230                 235                 240

 acg aat cca ttt cct aaa gac ttt tat ggt acc ctg att ctc aag cct      768
 Thr Asn Pro Phe Pro Lys Asp Phe Tyr Gly Thr Leu Ile Leu Lys Pro
                 245                 250                 255

 gtt tat gaa att caa ggt gtg atg aaa tgt gag tat cca ctg aga atg      816
 Val Tyr Glu Ile Gln Gly Val Met Lys Cys Glu Tyr Pro Leu Arg Met
             260                 265                 270

 atg ttc tat gag cat gag cat tat ggg gtt tgg gaa aga aag att tta      864
 Met Phe Tyr Glu His Glu His Tyr Gly Val Trp Glu Arg Lys Ile Leu
         275                 280                 285

 gag cct gaa gaa tgg gag tct gtc ttt att tca act att gag cct gtg      912
 Glu Pro Glu Glu Trp Glu Ser Val Phe Ile Ser Thr Ile Glu Pro Val
     290                 295                 300

 aga gtt aga ttc ctc atc aat caa taa                                  939
 Arg Val Arg Phe Leu Ile Asn Gln 
 305                 310





      <210> 12
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 12
  atg atg ctt ggc ctg gcc ttt cta gcc tgg ctg act gca aag gct tcc      48
  Met Met Leu Gly Leu Ala Phe Leu Ala Trp Leu Thr Ala Lys Ala Ser
    1               5                  10                  15

 cac ctt acc tcc aaa gtt gcc ctg ctg gaa ccc att ctt cat tcc aca       96
 His Leu Thr Ser Lys Val Ala Leu Leu Glu Pro Ile Leu His Ser Thr
              20                  25                  30

 gcc aga aag atc ttt cta aaa tgc aaa tct gac tgt gtc cct cct ctg      144
 Ala Arg Lys Ile Phe Leu Lys Cys Lys Ser Asp Cys Val Pro Pro Leu
          35                  40                  45

 ttg gaa cca ctc ctg tgc ctt tcc gtt gct ctc atg ctg aag gat ccc      192
 Leu Glu Pro Leu Leu Cys Leu Ser Val Ala Leu Met Leu Lys Asp Pro
      50                  55                  60

 cgt aca ttg tct ctg ttc tga                                          213
 Arg Thr Leu Ser Leu Phe 
  65                  70





      <210> 13
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 13
  atg ctc aaa atg tct gtg aag ccc cca ttg ctg gct gct gtt tct ctt      48
  Met Leu Lys Met Ser Val Lys Pro Pro Leu Leu Ala Ala Val Ser Leu
    1               5                  10                  15

 gaa cag ttc ccg ttg ctt ttt gga gta atc agc acc tgg gta aga aaa       96
 Glu Gln Phe Pro Leu Leu Phe Gly Val Ile Ser Thr Trp Val Arg Lys
              20                  25                  30

 ctg agt cac aca agg ata tat ttg tgt aac aca att tca aaa agg caa      144
 Leu Ser His Thr Arg Ile Tyr Leu Cys Asn Thr Ile Ser Lys Arg Gln
          35                  40                  45

 act ctt gct ctt gtt aac ggt aag gcc ttt ttg gca tcc cat att tgt      192
 Thr Leu Ala Leu Val Asn Gly Lys Ala Phe Leu Ala Ser His Ile Cys
      50                  55                  60

 gaa ctg tat cga tat gtt atc tca ttt gat ctg ata cat ccc ttc cca      240
 Glu Leu Tyr Arg Tyr Val Ile Ser Phe Asp Leu Ile His Pro Phe Pro
  65                  70                  75                  80

 ttt gct cac ata gaa gaa gtg aaa cag atg aag ggt ctc aaa gaa gct      288
 Phe Ala His Ile Glu Glu Val Lys Gln Met Lys Gly Leu Lys Glu Ala
                  85                  90                  95

 cat ctg tct atg aag gtg ctc atg gaa gca tct tgt ttt aca tat gat      336
 His Leu Ser Met Lys Val Leu Met Glu Ala Ser Cys Phe Thr Tyr Asp
             100                 105                 110

 gaa aat gga gag agc act tct ttt gac agg aaa ctt cac ttt ttt ggt      384
 Glu Asn Gly Glu Ser Thr Ser Phe Asp Arg Lys Leu His Phe Phe Gly
         115                 120                 125

 act gaa aac cgt cac aac agt cat tat gtc tgg ctt tag                  423
 Thr Glu Asn Arg His Asn Ser His Tyr Val Trp Leu 
     130                 135                 140





      <210> 14
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 14
  atg gcc cac gga gca tgc gca gct gtg gcc ttc cag cct gcc cct ctg      48
  Met Ala His Gly Ala Cys Ala Ala Val Ala Phe Gln Pro Ala Pro Leu
    1               5                  10                  15

 gcc ctc agg gca tcc aca tta atc tgg ata aag gct gct tct tca gcc       96
 Ala Leu Arg Ala Ser Thr Leu Ile Trp Ile Lys Ala Ala Ser Ser Ala
              20                  25                  30

 aca gct aag gtg cat gta ata gga atg aga gcc acc tgt gtt tca gaa      144
 Thr Ala Lys Val His Val Ile Gly Met Arg Ala Thr Cys Val Ser Glu
          35                  40                  45

 agc gtc tgg gat ttt aga gct gct tgt aac tgc agc cta aca cag cct      192
 Ser Val Trp Asp Phe Arg Ala Ala Cys Asn Cys Ser Leu Thr Gln Pro
      50                  55                  60

 cag ccg act gat aca tcc agt gtc gtc aaa aca gag cag aga aac agt      240
 Gln Pro Thr Asp Thr Ser Ser Val Val Lys Thr Glu Gln Arg Asn Ser
  65                  70                  75                  80

 gct tca aga aag agg caa ggc caa ctc aca aag tcc agt aaa gtt tgg      288
 Ala Ser Arg Lys Arg Gln Gly Gln Leu Thr Lys Ser Ser Lys Val Trp
                  85                  90                  95

 agc cat gga cgc tgc aac ttg tac aag agg ctt cag tgt tgt gtg agg      336
 Ser His Gly Arg Cys Asn Leu Tyr Lys Arg Leu Gln Cys Cys Val Arg
             100                 105                 110

 tca gac gcc ttt gcg gag tgg gcc tgg aga gca ggc agg aag gaa tca      384
 Ser Asp Ala Phe Ala Glu Trp Ala Trp Arg Ala Gly Arg Lys Glu Ser
         115                 120                 125

 gag tca gca atg atg gtt ctg ttg ctt aaa act agt gac act ggc aca      432
 Glu Ser Ala Met Met Val Leu Leu Leu Lys Thr Ser Asp Thr Gly Thr
     130                 135                 140

 ctc acc tga                                                          441
 Leu Thr 
 145





      <210> 15
      <211> 267
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(267)

      <400> 15
  atg atg ggg aac atg gta aga cca gtg aat tcc atg agc atg aac cta      48
  Met Met Gly Asn Met Val Arg Pro Val Asn Ser Met Ser Met Asn Leu
    1               5                  10                  15

 ctg ctg cac ttc ttt agc tgt aaa gtg agt gcc ttg gtc aga ggc gat       96
 Leu Leu His Phe Phe Ser Cys Lys Val Ser Ala Leu Val Arg Gly Asp
              20                  25                  30

 gct gtg tgg aat act atg atg gtg gat aag gca ttc cgt aag tcc aca      144
 Ala Val Trp Asn Thr Met Met Val Asp Lys Ala Phe Arg Lys Ser Thr
          35                  40                  45

 gat ggt agt ctt ggc aga agc att tca tac agg aca ggc aaa ccc ata      192
 Asp Gly Ser Leu Gly Arg Ser Ile Ser Tyr Arg Thr Gly Lys Pro Ile
      50                  55                  60

 tct gga gtg gtg cct gca tat cat gca gaa cca tct gtg aac cag gcc      240
 Ser Gly Val Val Pro Ala Tyr His Ala Glu Pro Ser Val Asn Gln Ala
  65                  70                  75                  80

 cta gtc ttc tgt tcc tct gtc aac tga                                  267
 Leu Val Phe Cys Ser Ser Val Asn 
                  85





      <210> 16
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 16
  atg gcg cca ctg ccc tcc acc ctg gct tgg ccc gtg cag gct ttc ttt      48
  Met Ala Pro Leu Pro Ser Thr Leu Ala Trp Pro Val Gln Ala Phe Phe
    1               5                  10                  15

 gcc ttt aag aag atg aaa ttg tta cca aag cag gag aag aat gtc aga       96
 Ala Phe Lys Lys Met Lys Leu Leu Pro Lys Gln Glu Lys Asn Val Arg
              20                  25                  30

 cac tct gca tgc ttg cca gag agc tcg cta gag gac gtg cag aag gtc      144
 His Ser Ala Cys Leu Pro Glu Ser Ser Leu Glu Asp Val Gln Lys Val
          35                  40                  45

 aaa gtc ctc cat cac cag agc aag ttc agc cac cag gcc cct taa          189
 Lys Val Leu His His Gln Ser Lys Phe Ser His Gln Ala Pro 
      50                  55                  60





      <210> 17
      <211> 621
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(621)

      <400> 17
  atg tgt gaa tgc ata ata cga aga atc tgg cta cag ttt cta ctc ctc      48
  Met Cys Glu Cys Ile Ile Arg Arg Ile Trp Leu Gln Phe Leu Leu Leu
    1               5                  10                  15

 tct gca agt gaa aag gcc cag aaa ggt gta aga gac cct ttg aat gga       96
 Ser Ala Ser Glu Lys Ala Gln Lys Gly Val Arg Asp Pro Leu Asn Gly
              20                  25                  30

 cat att caa caa att ctg ctt gtt aag aac aac ttt ggc tct ggc aag      144
 His Ile Gln Gln Ile Leu Leu Val Lys Asn Asn Phe Gly Ser Gly Lys
          35                  40                  45

 cag act ttg gag gct ctg gaa acg gga aaa gct ggg caa atc gaa tgc      192
 Gln Thr Leu Glu Ala Leu Glu Thr Gly Lys Ala Gly Gln Ile Glu Cys
      50                  55                  60

 cta ata ggg ctt gct tcc agt gtg gtc tac gag gac act tta aaa aag      240
 Leu Ile Gly Leu Ala Ser Ser Val Val Tyr Glu Asp Thr Leu Lys Lys
  65                  70                  75                  80

 att gtc caa gta gaa ata agc cgc ccc ctc gtc cat gcc cct tat gtc      288
 Ile Val Gln Val Glu Ile Ser Arg Pro Leu Val His Ala Pro Tyr Val
                  85                  90                  95

 aag gga atc act gga agg ccc act gcc cca ggg gac gaa gca ata tgg      336
 Lys Gly Ile Thr Gly Arg Pro Thr Ala Pro Gly Asp Glu Ala Ile Trp
             100                 105                 110

 aca gaa aag gaa ttc cta act tcc gag gga gca cct atc aaa tat ccg      384
 Thr Glu Lys Glu Phe Leu Thr Ser Glu Gly Ala Pro Ile Lys Tyr Pro
         115                 120                 125

 gaa gcc att agg aga tta tta ttg gct gta cag aaa cct aaa gag aat      432
 Glu Ala Ile Arg Arg Leu Leu Leu Ala Val Gln Lys Pro Lys Glu Asn
     130                 135                 140

 cga agc tgt aaa cta caa atg gtt ctt caa atg gag ccc cag atg cag      480
 Arg Ser Cys Lys Leu Gln Met Val Leu Gln Met Glu Pro Gln Met Gln
 145                 150                 155                 160

 ccc atg act aag atc tac tgg ggt ccc ctg gac tgg cct gct agc cca      528
 Pro Met Thr Lys Ile Tyr Trp Gly Pro Leu Asp Trp Pro Ala Ser Pro
                 165                 170                 175

 tgc tcc gat gtt gat gac atc gaa ggc aac cct cca gag gaa atc tca      576
 Cys Ser Asp Val Asp Asp Ile Glu Gly Asn Pro Pro Glu Glu Ile Ser
             180                 185                 190

 act gca caa ccc cta ctt cac ccc aat tca gca gta agc agt tag          621
 Thr Ala Gln Pro Leu Leu His Pro Asn Ser Ala Val Ser Ser 
         195                 200                 205





      <210> 18
      <211> 291
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(291)

      <400> 18
  atg acc aac atc ccc aca cct cta cat ctc tgt ccc ctg tat ctc ttc      48
  Met Thr Asn Ile Pro Thr Pro Leu His Leu Cys Pro Leu Tyr Leu Phe
    1               5                  10                  15

 ctt tct acc act aaa gtg ttc cct gct acc atc ctg gct tgt cca cat       96
 Leu Ser Thr Thr Lys Val Phe Pro Ala Thr Ile Leu Ala Cys Pro His
              20                  25                  30

 ggt gct ctc cat ctt cct cca cat cat gga cca cag gat tct tca ttt      144
 Gly Ala Leu His Leu Pro Pro His His Gly Pro Gln Asp Ser Ser Phe
          35                  40                  45

 gaa aat gac aac tat tct gtg ata aag aaa gtc aag ttt acc cat att      192
 Glu Asn Asp Asn Tyr Ser Val Ile Lys Lys Val Lys Phe Thr His Ile
      50                  55                  60

 cac tgg atg tct aca act ggt gtc ggc ttt caa aga gca tcc gat aca      240
 His Trp Met Ser Thr Thr Gly Val Gly Phe Gln Arg Ala Ser Asp Thr
  65                  70                  75                  80

 agg agg cag aag cat caa gag gca ccc agt agt tca ttg gtt caa cag      288
 Arg Arg Gln Lys His Gln Glu Ala Pro Ser Ser Ser Leu Val Gln Gln
                  85                  90                  95

 tga                                                                  291
 






      <210> 19
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 19
  atg gct ttc ctg ctt tgg aca tcc ttg tgt gat gat gtg ttg tta ctg      48
  Met Ala Phe Leu Leu Trp Thr Ser Leu Cys Asp Asp Val Leu Leu Leu
    1               5                  10                  15

 cag cta tct tgc aat cac aag gag atg gct gcc aac aac caa ggc tgg       96
 Gln Leu Ser Cys Asn His Lys Glu Met Ala Ala Asn Asn Gln Gly Trp
              20                  25                  30

 cag agc gag aag atg gtc aga gcc tgg acc tac gat gac atc acc aag      144
 Gln Ser Glu Lys Met Val Arg Ala Trp Thr Tyr Asp Asp Ile Thr Lys
          35                  40                  45

 cca ctg aac tac ctg gtc act gac cta ctg agc cta gga cca cct acc      192
 Pro Leu Asn Tyr Leu Val Thr Asp Leu Leu Ser Leu Gly Pro Pro Thr
      50                  55                  60

 tct aga gat ttt gtt aag aga gat aaa tca aat gtc caa att gct taa      240
 Ser Arg Asp Phe Val Lys Arg Asp Lys Ser Asn Val Gln Ile Ala 
  65                  70                  75





      <210> 20
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 20
  atg ctg ggg cct ctt gct tct ctg tct cat ctg cca ggg gtc cca gca      48
  Met Leu Gly Pro Leu Ala Ser Leu Ser His Leu Pro Gly Val Pro Ala
    1               5                  10                  15

 ctc tct ctc tgc tgc tct gtg gca ggc tac ttt gcc tct tgc tat cac       96
 Leu Ser Leu Cys Cys Ser Val Ala Gly Tyr Phe Ala Ser Cys Tyr His
              20                  25                  30

 tta cca gag agt tat gca gca cca cct gag gtg aag cca agg cca ctt      144
 Leu Pro Glu Ser Tyr Ala Ala Pro Pro Glu Val Lys Pro Arg Pro Leu
          35                  40                  45

 cca cca cca cca agt gtt cct acg ccg cca cca gaa ccc ccc act tcc      192
 Pro Pro Pro Pro Ser Val Pro Thr Pro Pro Pro Glu Pro Pro Thr Ser
      50                  55                  60

 ctc aac gcc ccc att ggc acc ccc acc ttc aat gcg gcc acc ggc gcc      240
 Leu Asn Ala Pro Ile Gly Thr Pro Thr Phe Asn Ala Ala Thr Gly Ala
  65                  70                  75                  80

 tcc act tct ccc cac acc gcc agc gct act atg tgc tcc tat gcc acc      288
 Ser Thr Ser Pro His Thr Ala Ser Ala Thr Met Cys Ser Tyr Ala Thr
                  85                  90                  95

 aac gcc acc aat gcc gca acc agc gcc ctc act tct ccc cgc gcc gcc      336
 Asn Ala Thr Asn Ala Ala Thr Ser Ala Leu Thr Ser Pro Arg Ala Ala
             100                 105                 110

 acc ggc gcc acg tat tcc tac ata gcc act ggc gcc acc aca cgc tcc      384
 Thr Gly Ala Thr Tyr Ser Tyr Ile Ala Thr Gly Ala Thr Thr Arg Ser
         115                 120                 125

 tac gcc acc acc agc gct ccc act tcc ccc aag gcc gcc aat ggt gcc      432
 Tyr Ala Thr Thr Ser Ala Pro Thr Ser Pro Lys Ala Ala Asn Gly Ala
     130                 135                 140

 cct act tct ccc cac acc gtc act ggt gct acc aca tgc tcc tac acc      480
 Pro Thr Ser Pro His Thr Val Thr Gly Ala Thr Thr Cys Ser Tyr Thr
 145                 150                 155                 160

 acc acc agc acc ccc act tcc ccg aca ctg cca cag gca ccc cca ctt      528
 Thr Thr Ser Thr Pro Thr Ser Pro Thr Leu Pro Gln Ala Pro Pro Leu
                 165                 170                 175

 ccc cca acg ccg cca ctg gcc tac acg ggc aac cag agt cca agg att      576
 Pro Pro Thr Pro Pro Leu Ala Tyr Thr Gly Asn Gln Ser Pro Arg Ile
             180                 185                 190

 aac ctc tgg acc act tca gca ccc atc tca gtc cga cca gcc ggt cac      624
 Asn Leu Trp Thr Thr Ser Ala Pro Ile Ser Val Arg Pro Ala Gly His
         195                 200                 205

 cta cct ggt gtt gca gcc tct ggc gtg gcc ggc agc agc tca cct cca      672
 Leu Pro Gly Val Ala Ala Ser Gly Val Ala Gly Ser Ser Ser Pro Pro
     210                 215                 220

 act gcc cgt gga gtg tgt gca aag atc cgg agc aac tgc gat gaa caa      720
 Thr Ala Arg Gly Val Cys Ala Lys Ile Arg Ser Asn Cys Asp Glu Gln
 225                 230                 235                 240

 cgc cag gcg cag gcc cct tta tag                                      744
 Arg Gln Ala Gln Ala Pro Leu 
                 245





      <210> 21
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 21
  atg ccc act ctc aca ctc ctc ttc aac aca gta ctg gaa gtc cta gcc      48
  Met Pro Thr Leu Thr Leu Leu Phe Asn Thr Val Leu Glu Val Leu Ala
    1               5                  10                  15

 aga aca atc aga cag gag aaa aaa ata aag gat ctc aaa atc agt aaa       96
 Arg Thr Ile Arg Gln Glu Lys Lys Ile Lys Asp Leu Lys Ile Ser Lys
              20                  25                  30

 gaa gaa gtc aaa ctg tca ctc ttt gat gat gat atg att tta tac cta      144
 Glu Glu Val Lys Leu Ser Leu Phe Asp Asp Asp Met Ile Leu Tyr Leu
          35                  40                  45

 gaa aac cct aaa gat tca tcc aga aag ctc cta aaa ctg gta aat gaa      192
 Glu Asn Pro Lys Asp Ser Ser Arg Lys Leu Leu Lys Leu Val Asn Glu
      50                  55                  60

 ttc agc aaa gtt tct gga tac aaa att aat gta cac aaa tca gtt gct      240
 Phe Ser Lys Val Ser Gly Tyr Lys Ile Asn Val His Lys Ser Val Ala
  65                  70                  75                  80

 ctt cta tac acc aac agt gac caa gct gag aat caa atc aag aac tca      288
 Leu Leu Tyr Thr Asn Ser Asp Gln Ala Glu Asn Gln Ile Lys Asn Ser
                  85                  90                  95

 acc act ttt aca ata gct gcc aaa aaa taa                              318
 Thr Thr Phe Thr Ile Ala Ala Lys Lys 
             100                 105





      <210> 22
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 22
  atg cta ctg tgc ata gat gta ctg tta ctc cct gtg gtg gca gct gga      48
  Met Leu Leu Cys Ile Asp Val Leu Leu Leu Pro Val Val Ala Ala Gly
    1               5                  10                  15

 agt aac aat gga ggt ggt gga aca gaa aca tgt gag gga tct gat gga       96
 Ser Asn Asn Gly Gly Gly Gly Thr Glu Thr Cys Glu Gly Ser Asp Gly
              20                  25                  30

 gat tta att act gaa gcc ctg act gat gcc aca gca gag att tac aat      144
 Asp Leu Ile Thr Glu Ala Leu Thr Asp Ala Thr Ala Glu Ile Tyr Asn
          35                  40                  45

 agt agt gag gga ata gaa gct cga gag aaa aga agg gaa ggg gat atg      192
 Ser Ser Glu Gly Ile Glu Ala Arg Glu Lys Arg Arg Glu Gly Asp Met
      50                  55                  60

 gca cgc taa                                                          201
 Ala Arg 
  65





      <210> 23
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 23
  atg gat cct cgg ctt ctg ttg tcc ctt gct gcc tat ctc ttt aat tta      48
  Met Asp Pro Arg Leu Leu Leu Ser Leu Ala Ala Tyr Leu Phe Asn Leu
    1               5                  10                  15

 gcc tac cag agt aaa gaa gtt gaa act gaa att agc ctt ttt cca ggg       96
 Ala Tyr Gln Ser Lys Glu Val Glu Thr Glu Ile Ser Leu Phe Pro Gly
              20                  25                  30

 gca gat agg aca gaa cat aaa atc tgg gaa atc ttg aag gcc aag ctt      144
 Ala Asp Arg Thr Glu His Lys Ile Trp Glu Ile Leu Lys Ala Lys Leu
          35                  40                  45

 att gcc atg tct ttt gaa gaa agc caa tct gaa gcc aca tct ttt aca      192
 Ile Ala Met Ser Phe Glu Glu Ser Gln Ser Glu Ala Thr Ser Phe Thr
      50                  55                  60

 aca tcc gta tgt ccc aca att gtc att att gac ttt cct tcc aag gac      240
 Thr Ser Val Cys Pro Thr Ile Val Ile Ile Asp Phe Pro Ser Lys Asp
  65                  70                  75                  80

 cag atc cga gaa gtc tta tca taa                                      264
 Gln Ile Arg Glu Val Leu Ser 
                  85





      <210> 24
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 24
  atg cgg tcg gtg agc cag cac gct ccc gta gga cgc atg cgc gcc ttt      48
  Met Arg Ser Val Ser Gln His Ala Pro Val Gly Arg Met Arg Ala Phe
    1               5                  10                  15

 ttc gcg ccg caa gtt cag gtg gcg ctt tgt cta cgc cct cct tcc ctg       96
 Phe Ala Pro Gln Val Gln Val Ala Leu Cys Leu Arg Pro Pro Ser Leu
              20                  25                  30

 gaa ctc tct acc cac aac tcc ccg ggg tcg cat gcg gtc aac gta ttc      144
 Glu Leu Ser Thr His Asn Ser Pro Gly Ser His Ala Val Asn Val Phe
          35                  40                  45

 ctg atg aca gtc tgc ctc tat ctt aca gta cta cta acc aat aac ctg      192
 Leu Met Thr Val Cys Leu Tyr Leu Thr Val Leu Leu Thr Asn Asn Leu
      50                  55                  60

 ctt ggc tca aag ggc cag cac ctt ctc tct aaa gcc caa gag gag ttt      240
 Leu Gly Ser Lys Gly Gln His Leu Leu Ser Lys Ala Gln Glu Glu Phe
  65                  70                  75                  80

 gag gta aat ggc ttt gca ata gtt acc atc aat ggc tgc tat ata aaa      288
 Glu Val Asn Gly Phe Ala Ile Val Thr Ile Asn Gly Cys Tyr Ile Lys
                  85                  90                  95

 ttt tct gtg att ttt gtg tgt gat agc act gtg gtc tgg gtg aat gta      336
 Phe Ser Val Ile Phe Val Cys Asp Ser Thr Val Val Trp Val Asn Val
             100                 105                 110

 cac aga cat aac tgg ctt aac cca aag tct ttg atc tcc tga              378
 His Arg His Asn Trp Leu Asn Pro Lys Ser Leu Ile Ser 
         115                 120                 125





      <210> 25
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 25
  atg ctg gcc ttg tac ttt ctt atc tgt atc cag tgt aac tac acg ttt      48
  Met Leu Ala Leu Tyr Phe Leu Ile Cys Ile Gln Cys Asn Tyr Thr Phe
    1               5                  10                  15

 tct gag gac agt cca gct tat ctg ccg agg att ccc cct gga aaa gta       96
 Ser Glu Asp Ser Pro Ala Tyr Leu Pro Arg Ile Pro Pro Gly Lys Val
              20                  25                  30

 cgc cga ttc gca ttt tgc att aag aaa ctg gaa aac ttt cct gtc ggt      144
 Arg Arg Phe Ala Phe Cys Ile Lys Lys Leu Glu Asn Phe Pro Val Gly
          35                  40                  45

 cct ggc gta gcg cct ccc gtg tcc ggg gta gac ctt gta ccg gct gaa      192
 Pro Gly Val Ala Pro Pro Val Ser Gly Val Asp Leu Val Pro Ala Glu
      50                  55                  60

 acc gca tag                                                          201
 Thr Ala 
  65





      <210> 26
      <211> 225
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(225)

      <400> 26
  atg aac aca tgg att ttc tgc ctg tcc ttt atg gct aat tcc agt acc      48
  Met Asn Thr Trp Ile Phe Cys Leu Ser Phe Met Ala Asn Ser Ser Thr
    1               5                  10                  15

 ttc ctg aag gct ctg gag tgc agc ctt gac ttc cac ggc aat gaa gcc       96
 Phe Leu Lys Ala Leu Glu Cys Ser Leu Asp Phe His Gly Asn Glu Ala
              20                  25                  30

 ttt cac tct agt tac gat gaa gct ggg aat gct att ctt ggc aag aga      144
 Phe His Ser Ser Tyr Asp Glu Ala Gly Asn Ala Ile Leu Gly Lys Arg
          35                  40                  45

 tct tcc aaa gga aac atc tgc aga acc tct gcc agt aag gtc agg gga      192
 Ser Ser Lys Gly Asn Ile Cys Arg Thr Ser Ala Ser Lys Val Arg Gly
      50                  55                  60

 aag ctg agg cag cta aaa act ttt cag tcc tag                          225
 Lys Leu Arg Gln Leu Lys Thr Phe Gln Ser 
  65                  70





      <210> 27
      <211> 141
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(141)

      <400> 27
  atg gtt tca cgt gct ttc ctg ggc tgg gtt ttc gca ctg gaa atc gtg      48
  Met Val Ser Arg Ala Phe Leu Gly Trp Val Phe Ala Leu Glu Ile Val
    1               5                  10                  15

 tat gct ttt gtg atc gtt cag atg gtc gag ctt ctg gac act gca gca       96
 Tyr Ala Phe Val Ile Val Gln Met Val Glu Leu Leu Asp Thr Ala Ala
              20                  25                  30

 aat att gcc aaa tac tcg acc cgt ggg gct aac gcc agc atc tga          141
 Asn Ile Ala Lys Tyr Ser Thr Arg Gly Ala Asn Ala Ser Ile 
          35                  40                  45





      <210> 28
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 28
  atg ctc tct cag cag ctg ctg gtc cag ctg tgg gca gcc gta caa gct      48
  Met Leu Ser Gln Gln Leu Leu Val Gln Leu Trp Ala Ala Val Gln Ala
    1               5                  10                  15

 gtt tac agc atc ctg gga cag gtg ctt gca aac ata tgg atg cca tgg       96
 Val Tyr Ser Ile Leu Gly Gln Val Leu Ala Asn Ile Trp Met Pro Trp
              20                  25                  30

 ggg atc cga gcc tgc agt gcc atg gtg gcg ttt gtg gcc aag aga cta      144
 Gly Ile Arg Ala Cys Ser Ala Met Val Ala Phe Val Ala Lys Arg Leu
          35                  40                  45

 tgt gca atc aga agg agg gaa gag ctg gcc cag cag aat ttg gtc cag      192
 Cys Ala Ile Arg Arg Arg Glu Glu Leu Ala Gln Gln Asn Leu Val Gln
      50                  55                  60

 ggt gag ggc cac aga aag aga gcc gtg atg ggg cct cag cag gag tgc      240
 Gly Glu Gly His Arg Lys Arg Ala Val Met Gly Pro Gln Gln Glu Cys
  65                  70                  75                  80

 atg gag gag gac gcc tac tgt ctg gac ctg gac cgg agg ctt ggc aag      288
 Met Glu Glu Asp Ala Tyr Cys Leu Asp Leu Asp Arg Arg Leu Gly Lys
                  85                  90                  95

 atg cag gac aac tgg aag ccg tga                                      312
 Met Gln Asp Asn Trp Lys Pro 
             100





      <210> 29
      <211> 777
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(777)

      <400> 29
  atg ctg cac ctt tgc atg tgt gcc ctc ttg gtc ttg ctt gga gaa gtt      48
  Met Leu His Leu Cys Met Cys Ala Leu Leu Val Leu Leu Gly Glu Val
    1               5                  10                  15

 gtg aca gct ctt gtc cac gct gac tgt cac cgc agg gag gca gct gct       96
 Val Thr Ala Leu Val His Ala Asp Cys His Arg Arg Glu Ala Ala Ala
              20                  25                  30

 ata cct ttg tgg att ggg aag acg ctg gaa ggg cag tgg aga gcc tca      144
 Ile Pro Leu Trp Ile Gly Lys Thr Leu Glu Gly Gln Trp Arg Ala Ser
          35                  40                  45

 cac atc cgg gag ctg aat tgt ggc tct ctg gtt gtc ctt tcc aga aca      192
 His Ile Arg Glu Leu Asn Cys Gly Ser Leu Val Val Leu Ser Arg Thr
      50                  55                  60

 ctt cca cct gca ccc ggg aac gct gct gcg cct gag agg ctg gag gct      240
 Leu Pro Pro Ala Pro Gly Asn Ala Ala Ala Pro Glu Arg Leu Glu Ala
  65                  70                  75                  80

 ctg aaa tac caa cgg ata aag aag ccc aaa aag tca tcc aag ggc tct      288
 Leu Lys Tyr Gln Arg Ile Lys Lys Pro Lys Lys Ser Ser Lys Gly Ser
                  85                  90                  95

 tcg aag tca aag aaa cga tcc ggc ctt cta gtg aac aaa ggc atg aca      336
 Ser Lys Ser Lys Lys Arg Ser Gly Leu Leu Val Asn Lys Gly Met Thr
             100                 105                 110

 gga ccc cat gtg gac ctc agg tgg tcc tgt tac cag ttc tgt ggt ggc      384
 Gly Pro His Val Asp Leu Arg Trp Ser Cys Tyr Gln Phe Cys Gly Gly
         115                 120                 125

 atc ttc caa atg tct gtc ttt agc cca ggt ccc ttc cct gag gtc atg      432
 Ile Phe Gln Met Ser Val Phe Ser Pro Gly Pro Phe Pro Glu Val Met
     130                 135                 140

 gct gat att tcc agt tgc cag ctg aac gtg cac ttg ggt gtt tca tac      480
 Ala Asp Ile Ser Ser Cys Gln Leu Asn Val His Leu Gly Val Ser Tyr
 145                 150                 155                 160

 gcc ttt acg atg tct aaa gca gag tta ttg atc agc ctc tcc agg tct      528
 Ala Phe Thr Met Ser Lys Ala Glu Leu Leu Ile Ser Leu Ser Arg Ser
                 165                 170                 175

 gct tct cct cag ctc ttc ctc ggt tta atc act agc act gac gat tct      576
 Ala Ser Pro Gln Leu Phe Leu Gly Leu Ile Thr Ser Thr Asp Asp Ser
             180                 185                 190

 gcc tcc cag act cag cag ctt ccc aac tct cag gtt ctg tgg ccc gat      624
 Ala Ser Gln Thr Gln Gln Leu Pro Asn Ser Gln Val Leu Trp Pro Asp
         195                 200                 205

 gaa gct gtc tgc ctc cga aag aag aag aga cat tct cgt cct gac ccc      672
 Glu Ala Val Cys Leu Arg Lys Lys Lys Arg His Ser Arg Pro Asp Pro
     210                 215                 220

 ttt gcc cgg ctc tca gac ttg tgc cac cgc cag ctt ccg gaa gac cag      720
 Phe Ala Arg Leu Ser Asp Leu Cys His Arg Gln Leu Pro Glu Asp Gln
 225                 230                 235                 240

 aca gcg att ctc aac agt gtg gac cac gat gac cca gga cat gcc act      768
 Thr Ala Ile Leu Asn Ser Val Asp His Asp Asp Pro Gly His Ala Thr
                 245                 250                 255

 ttg ctg tga                                                          777
 Leu Leu 






      <210> 30
      <211> 468
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(468)

      <400> 30
  atg cat ttc agt atc aga tgc gcg tcg caa cgt atc ccc tgt aga ggc      48
  Met His Phe Ser Ile Arg Cys Ala Ser Gln Arg Ile Pro Cys Arg Gly
    1               5                  10                  15

 aat ctg ctg ctg ctc cta agt gtc ctt tgg tgg ctg att gca gct tca       96
 Asn Leu Leu Leu Leu Leu Ser Val Leu Trp Trp Leu Ile Ala Ala Ser
              20                  25                  30

 agg ttt aag aaa tcc cat ctt tca gga agc ctg agg gga agg aag gaa      144
 Arg Phe Lys Lys Ser His Leu Ser Gly Ser Leu Arg Gly Arg Lys Glu
          35                  40                  45

 gta cgg gcg aaa tca tca gat tgg ctt ccc aga ttt ggg aat ctg aag      192
 Val Arg Ala Lys Ser Ser Asp Trp Leu Pro Arg Phe Gly Asn Leu Lys
      50                  55                  60

 cgg gcc cac atc ttc cgg cca act tcc att gaa ctt ccc agc act cga      240
 Arg Ala His Ile Phe Arg Pro Thr Ser Ile Glu Leu Pro Ser Thr Arg
  65                  70                  75                  80

 aag gga ccg aaa tgg aga gca aag gta tgt ggt tgt ccc tat cgg ggg      288
 Lys Gly Pro Lys Trp Arg Ala Lys Val Cys Gly Cys Pro Tyr Arg Gly
                  85                  90                  95

 act tcc cgc tgc atg tgc gtg tgg cca agg caa tcc tcg gcg agg gga      336
 Thr Ser Arg Cys Met Cys Val Trp Pro Arg Gln Ser Ser Ala Arg Gly
             100                 105                 110

 ctg cag tgc ttg ggg agc gag cat cat act agg tcg ata gag gag gag      384
 Leu Gln Cys Leu Gly Ser Glu His His Thr Arg Ser Ile Glu Glu Glu
         115                 120                 125

 atg cta tgt cca ttg cag cac tgg gga agt gtg gca gga agg cga ctt      432
 Met Leu Cys Pro Leu Gln His Trp Gly Ser Val Ala Gly Arg Arg Leu
     130                 135                 140

 ctt ttt aac tcc cac agc ttg gaa gac agt gtt taa                      468
 Leu Phe Asn Ser His Ser Leu Glu Asp Ser Val 
 145                 150                 155





      <210> 31
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 31
  atg tgc ttt ttt gtt att gtt gtt gtt act ccc ata acc aat gtt ggg      48
  Met Cys Phe Phe Val Ile Val Val Val Thr Pro Ile Thr Asn Val Gly
    1               5                  10                  15

 cat caa gat ctg gcc ctt aaa tct tct acg aac act gtt gtc aat acc       96
 His Gln Asp Leu Ala Leu Lys Ser Ser Thr Asn Thr Val Val Asn Thr
              20                  25                  30

 acg ggg ttt ctg ctt aat ttt gac ata tca gtc aga ctg atg cca gat      144
 Thr Gly Phe Leu Leu Asn Phe Asp Ile Ser Val Arg Leu Met Pro Asp
          35                  40                  45

 gaa cgt ctt ggt cct ggt ttt gat gat cat ggg ctt cgt gag gag ccc      192
 Glu Arg Leu Gly Pro Gly Phe Asp Asp His Gly Leu Arg Glu Glu Pro
      50                  55                  60

 gag tgt ggc cct gat gct aag tgg gag atg gct gcc aac tgc ata ggc      240
 Glu Cys Gly Pro Asp Ala Lys Trp Glu Met Ala Ala Asn Cys Ile Gly
  65                  70                  75                  80

 agc gcc aag gaa gag agc gca aac cca cgt tgt tca aag atc aat tgt      288
 Ser Ala Lys Glu Glu Ser Ala Asn Pro Arg Cys Ser Lys Ile Asn Cys
                  85                  90                  95

 aat cat ttg aca gtg tta ttg tga                                      312
 Asn His Leu Thr Val Leu Leu 
             100





      <210> 32
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 32
  atg cag tgc ttc agc ttc att aag acc atg atg atc ctc ttc aat ttg      48
  Met Gln Cys Phe Ser Phe Ile Lys Thr Met Met Ile Leu Phe Asn Leu
    1               5                  10                  15

 ctc atc ttt gta agt acg gac att gtg gac tct ttg ggg ctc cct ata       96
 Leu Ile Phe Val Ser Thr Asp Ile Val Asp Ser Leu Gly Leu Pro Ile
              20                  25                  30

 gga gca ggc act ggg ggc cca gaa aat aga agg gct cca ccc aag ttt      144
 Gly Ala Gly Thr Gly Gly Pro Glu Asn Arg Arg Ala Pro Pro Lys Phe
          35                  40                  45

 acc tac cac aga agg aaa ttc agt aca gag gaa att ctt ctg tat gac      192
 Thr Tyr His Arg Arg Lys Phe Ser Thr Glu Glu Ile Leu Leu Tyr Asp
      50                  55                  60

 ggg gag ctg aaa gga ggg agg gcc tac ctc tca tca gag caa cag tcc      240
 Gly Glu Leu Lys Gly Gly Arg Ala Tyr Leu Ser Ser Glu Gln Gln Ser
  65                  70                  75                  80

 tta ttc att cga caa aca ttc att gtc tag                              270
 Leu Phe Ile Arg Gln Thr Phe Ile Val 
                  85





      <210> 33
      <211> 822
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(822)

      <400> 33
  atg ctg cct tgc ctc gcc ctg ctt ctc ctg atg gag ctg tcc gtg tgc      48
  Met Leu Pro Cys Leu Ala Leu Leu Leu Leu Met Glu Leu Ser Val Cys
    1               5                  10                  15

 act gtg gca ggt gat ggt gga gag gaa cag aca ctc agc act gaa gca       96
 Thr Val Ala Gly Asp Gly Gly Glu Glu Gln Thr Leu Ser Thr Glu Ala
              20                  25                  30

 gag acc tgg gta att gtg gcc ttg gag gaa ggc gct ggc ccc agc att      144
 Glu Thr Trp Val Ile Val Ala Leu Glu Glu Gly Ala Gly Pro Ser Ile
          35                  40                  45

 cag ctc cag ctg cag gag gtg aag acg ggc aag gca agc cag ttc ttt      192
 Gln Leu Gln Leu Gln Glu Val Lys Thr Gly Lys Ala Ser Gln Phe Phe
      50                  55                  60

 ggg ctg atg ggg aag cga gtg gga gga aga cct ctg atc cag cca agg      240
 Gly Leu Met Gly Lys Arg Val Gly Gly Arg Pro Leu Ile Gln Pro Arg
  65                  70                  75                  80

 aga aaa aaa gca gag ggc agg aat ggc ctg ggc tct gta gtc tgt tca      288
 Arg Lys Lys Ala Glu Gly Arg Asn Gly Leu Gly Ser Val Val Cys Ser
                  85                  90                  95

 gtg gcc tca ctg gta tgt caa cag gcc aag agc cct ttt gca gaa tcg      336
 Val Ala Ser Leu Val Cys Gln Gln Ala Lys Ser Pro Phe Ala Glu Ser
             100                 105                 110

 cag aga aat act gaa cag ccc tgg tcc tac ccc cag gtg gga aaa cag      384
 Gln Arg Asn Thr Glu Gln Pro Trp Ser Tyr Pro Gln Val Gly Lys Gln
         115                 120                 125

 gct tgg gac aca gat ccc atc cag gca acc tca ctg agg ccg aaa caa      432
 Ala Trp Asp Thr Asp Pro Ile Gln Ala Thr Ser Leu Arg Pro Lys Gln
     130                 135                 140

 cag ttc ctc aga acc agc gtc tgc agt gta cac aaa ggt cgg agc cag      480
 Gln Phe Leu Arg Thr Ser Val Cys Ser Val His Lys Gly Arg Ser Gln
 145                 150                 155                 160

 gac agt cct gag ggg gat ggc ctt ccc aaa gga tac tgt act tgc caa      528
 Asp Ser Pro Glu Gly Asp Gly Leu Pro Lys Gly Tyr Cys Thr Cys Gln
                 165                 170                 175

 tca caa gag caa cag aga aat gac aga cag atc cct agg ctg tgg cct      576
 Ser Gln Glu Gln Gln Arg Asn Asp Arg Gln Ile Pro Arg Leu Trp Pro
             180                 185                 190

 gtc att tcc tat gcc ttc atc cca ctg ctg agg acc act gag aag gtg      624
 Val Ile Ser Tyr Ala Phe Ile Pro Leu Leu Arg Thr Thr Glu Lys Val
         195                 200                 205

 cct gaa cag atg cca tcg cta tgg caa aat cta gag atc cta cag ctt      672
 Pro Glu Gln Met Pro Ser Leu Trp Gln Asn Leu Glu Ile Leu Gln Leu
     210                 215                 220

 att gcc atc atg gtc aag gca gag gaa ccc aag aca act cac cat gtg      720
 Ile Ala Ile Met Val Lys Ala Glu Glu Pro Lys Thr Thr His His Val
 225                 230                 235                 240

 ccg gcg gag atg gat ctg gca gtc ttt gaa cat gct tat gga ata cca      768
 Pro Ala Glu Met Asp Leu Ala Val Phe Glu His Ala Tyr Gly Ile Pro
                 245                 250                 255

 gag cag agc cag gag ggt caa ggg tac cct cca aat cta acc cca gat      816
 Glu Gln Ser Gln Glu Gly Gln Gly Tyr Pro Pro Asn Leu Thr Pro Asp
             260                 265                 270

 gcc taa                                                              822
 Ala 






      <210> 34
      <211> 1005
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1005)

      <400> 34
  atg gct gcc gaa ctc aac ggc ctg ctc tgg cgg ctt ggc tgg gct ggg      48
  Met Ala Ala Glu Leu Asn Gly Leu Leu Trp Arg Leu Gly Trp Ala Gly
    1               5                  10                  15

 ctt ggg ggg ccc ttc cag gcc cca aag gag gaa gga agc tgc tgc aat       96
 Leu Gly Gly Pro Phe Gln Ala Pro Lys Glu Glu Gly Ser Cys Cys Asn
              20                  25                  30

 aag aag caa gat gtc cag ggc gcg ggg tct tcc tac aat tgc cgc ttc      144
 Lys Lys Gln Asp Val Gln Gly Ala Gly Ser Ser Tyr Asn Cys Arg Phe
          35                  40                  45

 ttt gtc ctc ccc tgc tgc ttc ttt gac ttc att gga aga tac tcc cgg      192
 Phe Val Leu Pro Cys Cys Phe Phe Asp Phe Ile Gly Arg Tyr Ser Arg
      50                  55                  60

 agg cag agt aag aag act cag tac cgg gaa tac ctt gac ttc att aaa      240
 Arg Gln Ser Lys Lys Thr Gln Tyr Arg Glu Tyr Leu Asp Phe Ile Lys
  65                  70                  75                  80

 gaa gtg ggc ttc acc tgt ggg ttt cac gtg gac gaa gac tgc ctc agg      288
 Glu Val Gly Phe Thr Cys Gly Phe His Val Asp Glu Asp Cys Leu Arg
                  85                  90                  95

 att cct tca acc aaa aga gtc tgt ctc gtt gga aaa tcc aga aca tac      336
 Ile Pro Ser Thr Lys Arg Val Cys Leu Val Gly Lys Ser Arg Thr Tyr
             100                 105                 110

 cct tcc tcc aga gaa gct tcc gtg gat gaa aag agg act cag tac att      384
 Pro Ser Ser Arg Glu Ala Ser Val Asp Glu Lys Arg Thr Gln Tyr Ile
         115                 120                 125

 aag agc agg cgg ggc tgc cct gta agc cca cct ggc tgg gag ctt tcc      432
 Lys Ser Arg Arg Gly Cys Pro Val Ser Pro Pro Gly Trp Glu Leu Ser
     130                 135                 140

 cct tct cca cgc tgg gtt gct gct ggc agt gct ggt cac tgt gac ggt      480
 Pro Ser Pro Arg Trp Val Ala Ala Gly Ser Ala Gly His Cys Asp Gly
 145                 150                 155                 160

 cag caa gct ctg gac gcc agg gtc gga gaa aag gct gag cgt gtg agg      528
 Gln Gln Ala Leu Asp Ala Arg Val Gly Glu Lys Ala Glu Arg Val Arg
                 165                 170                 175

 aac tgt gcc gcc ctg cca cga gat ttt att gac caa gtg gtt ttg caa      576
 Asn Cys Ala Ala Leu Pro Arg Asp Phe Ile Asp Gln Val Val Leu Gln
             180                 185                 190

 gta gcg aat tta ctg tta ggt gga aag caa tta aac aca aga agt tct      624
 Val Ala Asn Leu Leu Leu Gly Gly Lys Gln Leu Asn Thr Arg Ser Ser
         195                 200                 205

 cga aat ggg agt ttg aag acc tgg aat ggg gga gag agc cta tct ctg      672
 Arg Asn Gly Ser Leu Lys Thr Trp Asn Gly Gly Glu Ser Leu Ser Leu
     210                 215                 220

 gca gaa gta gcc aac gag ctg gac acg gag acc ctg cgg agg ctg aag      720
 Ala Glu Val Ala Asn Glu Leu Asp Thr Glu Thr Leu Arg Arg Leu Lys
 225                 230                 235                 240

 cgg gag tgt ggg ggc ctg cag acg ctg ctc cgg aac agc cac cag gtg      768
 Arg Glu Cys Gly Gly Leu Gln Thr Leu Leu Arg Asn Ser His Gln Val
                 245                 250                 255

 ttc caa gtt gtg aat ggg aga gtt cac atc cgc gac tgg cga gag gag      816
 Phe Gln Val Val Asn Gly Arg Val His Ile Arg Asp Trp Arg Glu Glu
             260                 265                 270

 aca ctg tgg aag aca aag caa ccg gaa gcg aaa cag aga ctg ctc tct      864
 Thr Leu Trp Lys Thr Lys Gln Pro Glu Ala Lys Gln Arg Leu Leu Ser
         275                 280                 285

 gaa gcc tgc aaa acc cgc ctc tgc tgg ttc ttc atg cat cac cct gat      912
 Glu Ala Cys Lys Thr Arg Leu Cys Trp Phe Phe Met His His Pro Asp
     290                 295                 300

 ggc tgc gct ctg tcc acg gac tgc tgc ccg ttt gcc cat ggg cct gcg      960
 Gly Cys Ala Leu Ser Thr Asp Cys Cys Pro Phe Ala His Gly Pro Ala
 305                 310                 315                 320

 gag ctg cgg cca ccc cgg acc acc ccg agg aag aag att tca tga         1005
 Glu Leu Arg Pro Pro Arg Thr Thr Pro Arg Lys Lys Ile Ser 
                 325                 330





      <210> 35
      <211> 876
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(876)

      <400> 35
  atg gca cca gtc caa aca tta agg acg tct aca gca aca ctg ctc ttc      48
  Met Ala Pro Val Gln Thr Leu Arg Thr Ser Thr Ala Thr Leu Leu Phe
    1               5                  10                  15

 atg atg gta aac att gag gat gtc tac ggc aac act gct ctt cat gat       96
 Met Met Val Asn Ile Glu Asp Val Tyr Gly Asn Thr Ala Leu His Asp
              20                  25                  30

 gct gtc tat gat aag ggg act tca ctg gca gga agc ctg ctt tcc cac      144
 Ala Val Tyr Asp Lys Gly Thr Ser Leu Ala Gly Ser Leu Leu Ser His
          35                  40                  45

 cat gca aat act gaa gca cta aac aag gaa tca ttc act gcc att cag      192
 His Ala Asn Thr Glu Ala Leu Asn Lys Glu Ser Phe Thr Ala Ile Gln
      50                  55                  60

 aga gcc ttt agc aat ttg ctt gtg ggt aat ctt tca ata gaa cac gac      240
 Arg Ala Phe Ser Asn Leu Leu Val Gly Asn Leu Ser Ile Glu His Asp
  65                  70                  75                  80

 tta aaa gtg gct tca gag gaa aag caa gaa acg ctt gaa aga agt gaa      288
 Leu Lys Val Ala Ser Glu Glu Lys Gln Glu Thr Leu Glu Arg Ser Glu
                  85                  90                  95

 aat aaa cag cca gag gaa aag gaa tat att cag gaa att aag agt att      336
 Asn Lys Gln Pro Glu Glu Lys Glu Tyr Ile Gln Glu Ile Lys Ser Ile
             100                 105                 110

 aga gaa ata aat gct aac ttt gaa aaa agt gca aga ctc aat gag gaa      384
 Arg Glu Ile Asn Ala Asn Phe Glu Lys Ser Ala Arg Leu Asn Glu Glu
         115                 120                 125

 atg aca aca aaa acg atg tcc cag tat tgt caa cag ctt aat ggc ctc      432
 Met Thr Thr Lys Thr Met Ser Gln Tyr Cys Gln Gln Leu Asn Gly Leu
     130                 135                 140

 aaa gct gag aat aca agg ctg aat tca aaa ttg gag aag gaa gaa cac      480
 Lys Ala Glu Asn Thr Arg Leu Asn Ser Lys Leu Glu Lys Glu Glu His
 145                 150                 155                 160

 cac aca gat gga ctg gaa gct gaa gtt gaa ttc ttc cat tct agg ctg      528
 His Thr Asp Gly Leu Glu Ala Glu Val Glu Phe Phe His Ser Arg Leu
                 165                 170                 175

 gct gct gct ata aat gag cac aat gaa agt tta gaa acg aaa gac cta      576
 Ala Ala Ala Ile Asn Glu His Asn Glu Ser Leu Glu Thr Lys Asp Leu
             180                 185                 190

 gaa ctt gtt tta cag aga gca cat aat ttt tcc gta cat aaa aaa ata      624
 Glu Leu Val Leu Gln Arg Ala His Asn Phe Ser Val His Lys Lys Ile
         195                 200                 205

 agt tct act gtt tct caa cta aaa gat aaa aat gag ttg ctt act gaa      672
 Ser Ser Thr Val Ser Gln Leu Lys Asp Lys Asn Glu Leu Leu Thr Glu
     210                 215                 220

 caa ttt tct aaa gct cag atg aag ttc aat acc tta aaa ggt aag ctc      720
 Gln Phe Ser Lys Ala Gln Met Lys Phe Asn Thr Leu Lys Gly Lys Leu
 225                 230                 235                 240

 cat gag ata aga gat gct ctc agg gaa aag aca ttg gct tta gaa agt      768
 His Glu Ile Arg Asp Ala Leu Arg Glu Lys Thr Leu Ala Leu Glu Ser
                 245                 250                 255

 gta cag atg gac caa agg caa gca cag cat cga ata aag gaa atg gag      816
 Val Gln Met Asp Gln Arg Gln Ala Gln His Arg Ile Lys Glu Met Glu
             260                 265                 270

 cag att cat cca aat gag gaa act aaa gga gtc gat cca ccg gaa agc      864
 Gln Ile His Pro Asn Glu Glu Thr Lys Gly Val Asp Pro Pro Glu Ser
         275                 280                 285

 aca act gtg tag                                                      876
 Thr Thr Val 
     290





      <210> 36
      <211> 432
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(432)

      <400> 36
  atg acc ctg aaa ggt ggt gag ctt ccc att ccc aga ggt gcc ttc ctc      48
  Met Thr Leu Lys Gly Gly Glu Leu Pro Ile Pro Arg Gly Ala Phe Leu
    1               5                  10                  15

 ata ctg ctc ctc tca cct gtg agc aca gac cag gcc aac acc acc act       96
 Ile Leu Leu Leu Ser Pro Val Ser Thr Asp Gln Ala Asn Thr Thr Thr
              20                  25                  30

 gct gag atc cac agc cag ctc acc cca cgg cta aat ctc acc atc cta      144
 Ala Glu Ile His Ser Gln Leu Thr Pro Arg Leu Asn Leu Thr Ile Leu
          35                  40                  45

 tca tcc cag aaa aat gca gag acc aac gca att cat cac ata cag tac      192
 Ser Ser Gln Lys Asn Ala Glu Thr Asn Ala Ile His His Ile Gln Tyr
      50                  55                  60

 aac gtt gac gga aag tgc tgg gcc cgc cca cag aaa caa tgc act atg      240
 Asn Val Asp Gly Lys Cys Trp Ala Arg Pro Gln Lys Gln Cys Thr Met
  65                  70                  75                  80

 tac acg ggc agg ggg caa gtc ttc agc aga ggg tca cgt acc atc gaa      288
 Tyr Thr Gly Arg Gly Gln Val Phe Ser Arg Gly Ser Arg Thr Ile Glu
                  85                  90                  95

 atc aca aac cag acc atc agc aaa cag aca tct tac agc aaa gaa atc      336
 Ile Thr Asn Gln Thr Ile Ser Lys Gln Thr Ser Tyr Ser Lys Glu Ile
             100                 105                 110

 cct cta agc atc cag gag aat gca cag atg ggg ctg cgc atc tac tca      384
 Pro Leu Ser Ile Gln Glu Asn Ala Gln Met Gly Leu Arg Ile Tyr Ser
         115                 120                 125

 gca cca gcg tac gcc cat cag cac act ggc att cac tcg cca gca tga      432
 Ala Pro Ala Tyr Ala His Gln His Thr Gly Ile His Ser Pro Ala 
     130                 135                 140





      <210> 37
      <211> 390
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(390)

      <400> 37
  atg ggg cca tat tgg gtt tgg ctc tgc ctt gca gct ggc agt cca aac      48
  Met Gly Pro Tyr Trp Val Trp Leu Cys Leu Ala Ala Gly Ser Pro Asn
    1               5                  10                  15

 act gag gac atg cat att tct gca ggc ctc act atg gtc atc tgt cca       96
 Thr Glu Asp Met His Ile Ser Ala Gly Leu Thr Met Val Ile Cys Pro
              20                  25                  30

 aac ccc aga atc cag aga ctc aaa acg aaa tac agt cat aca aag gcg      144
 Asn Pro Arg Ile Gln Arg Leu Lys Thr Lys Tyr Ser His Thr Lys Ala
          35                  40                  45

 aca cag ctt aca gct tat tgc cag cta aaa caa aaa cat cga tac tcc      192
 Thr Gln Leu Thr Ala Tyr Cys Gln Leu Lys Gln Lys His Arg Tyr Ser
      50                  55                  60

 tca gag gaa tat tac aga acc cag agt ctc cac aat gta aca ttc ata      240
 Ser Glu Glu Tyr Tyr Arg Thr Gln Ser Leu His Asn Val Thr Phe Ile
  65                  70                  75                  80

 aat atg caa gat aca atc caa aat gac tca ata tac aaa gaa cca gaa      288
 Asn Met Gln Asp Thr Ile Gln Asn Asp Ser Ile Tyr Lys Glu Pro Glu
                  85                  90                  95

 gaa tat gac cca ttc tca agg gaa aag aca ttt aac aga aac caa tcc      336
 Glu Tyr Asp Pro Phe Ser Arg Glu Lys Thr Phe Asn Arg Asn Gln Ser
             100                 105                 110

 caa aat gac aca aat gtt cag aca cat aag gaa cag acc aat gaa aca      384
 Gln Asn Asp Thr Asn Val Gln Thr His Lys Glu Gln Thr Asn Glu Thr
         115                 120                 125

 gag taa                                                              390
 Glu 






      <210> 38
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 38
  atg gct gca ctc ttg ctg aga cat gtt gga gtg gtc att gcc tcc gag      48
  Met Ala Ala Leu Leu Leu Arg His Val Gly Val Val Ile Ala Ser Glu
    1               5                  10                  15

 cgc act tta gcc ctc agc ttt gta tca gaa atg ctg ttc ctt tgg gaa       96
 Arg Thr Leu Ala Leu Ser Phe Val Ser Glu Met Leu Phe Leu Trp Glu
              20                  25                  30

 tca tgg cca aag aag aga tgg aat ggt tct gga ata aga aca cag gtt      144
 Ser Trp Pro Lys Lys Arg Trp Asn Gly Ser Gly Ile Arg Thr Gln Val
          35                  40                  45

 caa acc gtc ccg tat ctc ccc acg tca cta tct aga gtt ggt gtc ttc      192
 Gln Thr Val Pro Tyr Leu Pro Thr Ser Leu Ser Arg Val Gly Val Phe
      50                  55                  60

 cta tgt cga tgt cca tct gcc acc atg gct ctg ggc tgg cag ctg tgt      240
 Leu Cys Arg Cys Pro Ser Ala Thr Met Ala Leu Gly Trp Gln Leu Cys
  65                  70                  75                  80

 gaa gaa ctg agc ttg cct aat ctg ggc cta gaa gca gtt att ctc tct      288
 Glu Glu Leu Ser Leu Pro Asn Leu Gly Leu Glu Ala Val Ile Leu Ser
                  85                  90                  95

 cca tat tgg gct ttg att tgt gct gaa ggt cag ctt ttg gct cct cct      336
 Pro Tyr Trp Ala Leu Ile Cys Ala Glu Gly Gln Leu Leu Ala Pro Pro
             100                 105                 110

 tcc tgg gat att gga aac aat gcc agc tct gtg gct tct gcc ctg ggg      384
 Ser Trp Asp Ile Gly Asn Asn Ala Ser Ser Val Ala Ser Ala Leu Gly
         115                 120                 125

 act ggg ggt gag gct ttg ggc acc act gcc tgg ctc tca gat gat tta      432
 Thr Gly Gly Glu Ala Leu Gly Thr Thr Ala Trp Leu Ser Asp Asp Leu
     130                 135                 140

 cat tgg ttg gtc ttc agt gct ttc aca tag                              462
 His Trp Leu Val Phe Ser Ala Phe Thr 
 145                 150





      <210> 39
      <211> 705
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(705)

      <400> 39
  atg tat ctt ttc ctg tgt cct cca ctg gcc ctt gtc cag tgc gcc ctg      48
  Met Tyr Leu Phe Leu Cys Pro Pro Leu Ala Leu Val Gln Cys Ala Leu
    1               5                  10                  15

 aag gac cca cgc agc aag tac tca cta gga gga cga aca acc ctg att       96
 Lys Asp Pro Arg Ser Lys Tyr Ser Leu Gly Gly Arg Thr Thr Leu Ile
              20                  25                  30

 ata act tta cag ggc tca gga aag aaa aac aac atc cct cat cca tct      144
 Ile Thr Leu Gln Gly Ser Gly Lys Lys Asn Asn Ile Pro His Pro Ser
          35                  40                  45

 tct ctt tca gaa agg gtc atg aca gcc aag gat ggc ttt gta agc aga      192
 Ser Leu Ser Glu Arg Val Met Thr Ala Lys Asp Gly Phe Val Ser Arg
      50                  55                  60

 tgc cat ctg ctg atg cag ccg aag cag cag gag aat ggt tgc tgg ccc      240
 Cys His Leu Leu Met Gln Pro Lys Gln Gln Glu Asn Gly Cys Trp Pro
  65                  70                  75                  80

 act cta cag gac agc ttg cta tgc aca gcg ctg gtg gac aag ctc ttg      288
 Thr Leu Gln Asp Ser Leu Leu Cys Thr Ala Leu Val Asp Lys Leu Leu
                  85                  90                  95

 gtg ttt ctg ggc agg tgt ttc tgc aca gca gtt gag gtg gtg atg ctg      336
 Val Phe Leu Gly Arg Cys Phe Cys Thr Ala Val Glu Val Val Met Leu
             100                 105                 110

 gtg aca tgc agg aca gca gct gct gtt tct gct ttt ctc atc gtg ggc      384
 Val Thr Cys Arg Thr Ala Ala Ala Val Ser Ala Phe Leu Ile Val Gly
         115                 120                 125

 agg gtt agc agc ccc gtg tgc aga gcc gtg agc gtg cag ccc tgg act      432
 Arg Val Ser Ser Pro Val Cys Arg Ala Val Ser Val Gln Pro Trp Thr
     130                 135                 140

 ctg acc gct gac cac act ccc ggc aga tac tgc ctc aag ctc gtc tgc      480
 Leu Thr Ala Asp His Thr Pro Gly Arg Tyr Cys Leu Lys Leu Val Cys
 145                 150                 155                 160

 cgg cag ctc tgc ttg tgc ctt cta gct gag ttc agt gag aaa gga aca      528
 Arg Gln Leu Cys Leu Cys Leu Leu Ala Glu Phe Ser Glu Lys Gly Thr
                 165                 170                 175

 att tgt ctg cat cag aat ttc atg tgt act ttt gca gca atc agc att      576
 Ile Cys Leu His Gln Asn Phe Met Cys Thr Phe Ala Ala Ile Ser Ile
             180                 185                 190

 gaa agt gag gac aca act gag cag ctg gct ggc tct ttc ctc att att      624
 Glu Ser Glu Asp Thr Thr Glu Gln Leu Ala Gly Ser Phe Leu Ile Ile
         195                 200                 205

 ttt tgg aaa gtt gac cct gaa ctt ttg tgt cat cga agt caa act gcc      672
 Phe Trp Lys Val Asp Pro Glu Leu Leu Cys His Arg Ser Gln Thr Ala
     210                 215                 220

 aaa gaa aat gta gat atc tgg gga agt ctt taa                          705
 Lys Glu Asn Val Asp Ile Trp Gly Ser Leu 
 225                 230





      <210> 40
      <211> 345
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(345)

      <400> 40
  atg gcc ctg atc aca tgg ctc ccg agg ccc acg tgg cct ctg gat ttt      48
  Met Ala Leu Ile Thr Trp Leu Pro Arg Pro Thr Trp Pro Leu Asp Phe
    1               5                  10                  15

 cag tta tat gag aca atg tgg gtg aag cag gcg tat tac ctg cct ttt       96
 Gln Leu Tyr Glu Thr Met Trp Val Lys Gln Ala Tyr Tyr Leu Pro Phe
              20                  25                  30

 aca act gga gaa aca ggt tgg aga gct tac gta aat cac cca agg ttt      144
 Thr Thr Gly Glu Thr Gly Trp Arg Ala Tyr Val Asn His Pro Arg Phe
          35                  40                  45

 ccc agc tgt caa gtg gtg gtg cct gag ccc gag ccc gta tct gct gcc      192
 Pro Ser Cys Gln Val Val Val Pro Glu Pro Glu Pro Val Ser Ala Ala
      50                  55                  60

 tcc aaa gcc cat gcc ctt cca cca ccg cag gcc tct gaa gga aga gct      240
 Ser Lys Ala His Ala Leu Pro Pro Pro Gln Ala Ser Glu Gly Arg Ala
  65                  70                  75                  80

 gtt gat ggc acc agc aga cag gaa aca atg aag ctc tca agc act gtg      288
 Val Asp Gly Thr Ser Arg Gln Glu Thr Met Lys Leu Ser Ser Thr Val
                  85                  90                  95

 cat ggg agc cat ggg ctg ccg ggc tgc cag gct gcc agc cgg att ccg      336
 His Gly Ser His Gly Leu Pro Gly Cys Gln Ala Ala Ser Arg Ile Pro
             100                 105                 110

 gat gag tga                                                          345
 Asp Glu 






      <210> 41
      <211> 474
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(474)

      <400> 41
  atg agg aaa atc gtc gtg gga ctt act ttc ctt ata aca cgg act tgt      48
  Met Arg Lys Ile Val Val Gly Leu Thr Phe Leu Ile Thr Arg Thr Cys
    1               5                  10                  15

 gtg gta aaa gct tcc act gct tct tcc cac aca gag gac tgc ttt cag       96
 Val Val Lys Ala Ser Thr Ala Ser Ser His Thr Glu Asp Cys Phe Gln
              20                  25                  30

 tgc ata cct cag gtc act gag ttg caa gct gtt tta gaa att att act      144
 Cys Ile Pro Gln Val Thr Glu Leu Gln Ala Val Leu Glu Ile Ile Thr
          35                  40                  45

 aat aaa act ggt caa gcc ttg act gtt ctt gcc cgg caa gag act cag      192
 Asn Lys Thr Gly Gln Ala Leu Thr Val Leu Ala Arg Gln Glu Thr Gln
      50                  55                  60

 atg agg aat gct atc tac caa aat aga cta gct ctc gac tac ttg cta      240
 Met Arg Asn Ala Ile Tyr Gln Asn Arg Leu Ala Leu Asp Tyr Leu Leu
  65                  70                  75                  80

 gca gct aaa gga gga gtt tgt gga aaa ttt aac ctt act aat tgc tgt      288
 Ala Ala Lys Gly Gly Val Cys Gly Lys Phe Asn Leu Thr Asn Cys Cys
                  85                  90                  95

 ctc cac ata gat gat caa ggg caa gta gtt gaa gac ata gtt aaa gat      336
 Leu His Ile Asp Asp Gln Gly Gln Val Val Glu Asp Ile Val Lys Asp
             100                 105                 110

 ata aca aaa ctg gca cat gta cag tgc gag ccc ttc aca gac acc tgc      384
 Ile Thr Lys Leu Ala His Val Gln Cys Glu Pro Phe Thr Asp Thr Cys
         115                 120                 125

 tgg tcc ctc cca ctt ggc caa gga aac act gtg gtt aat gag tct cag      432
 Trp Ser Leu Pro Leu Gly Gln Gly Asn Thr Val Val Asn Glu Ser Gln
     130                 135                 140

 aaa agt gat gtg aaa gtg aga agt aaa agt gac aga ggc taa              474
 Lys Ser Asp Val Lys Val Arg Ser Lys Ser Asp Arg Gly 
 145                 150                 155





      <210> 42
      <211> 468
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(468)

      <400> 42
  atg tgg gca aag gtg ctt cac ctg atg ttg ggc tgg aaa aac ctg aag      48
  Met Trp Ala Lys Val Leu His Leu Met Leu Gly Trp Lys Asn Leu Lys
    1               5                  10                  15

 gcc gcc cta cat ttg ccg agc tgc tgc ggg ctg tca cag aga ttg cgg       96
 Ala Ala Leu His Leu Pro Ser Cys Cys Gly Leu Ser Gln Arg Leu Arg
              20                  25                  30

 aaa cct ggt gac cgg aaa cag aat gcc aac cca aag agt cat ctt gca      144
 Lys Pro Gly Asp Arg Lys Gln Asn Ala Asn Pro Lys Ser His Leu Ala
          35                  40                  45

 aaa ctg tca ttt att gtg aat atc ttc acc ata tgg ggt aaa tta aaa      192
 Lys Leu Ser Phe Ile Val Asn Ile Phe Thr Ile Trp Gly Lys Leu Lys
      50                  55                  60

 agc tgc ttt ccc ctt ggt acg gcg aaa acc atc att tca atg tat cta      240
 Ser Cys Phe Pro Leu Gly Thr Ala Lys Thr Ile Ile Ser Met Tyr Leu
  65                  70                  75                  80

 cat cct tcc agt cgc tcc ccc tac ccc ctt ccc tac ttt tat cgg ggc      288
 His Pro Ser Ser Arg Ser Pro Tyr Pro Leu Pro Tyr Phe Tyr Arg Gly
                  85                  90                  95

 ctt ctg tat gga gac tgc aga aaa ccc gcc agt gtt gcg aac act tgg      336
 Leu Leu Tyr Gly Asp Cys Arg Lys Pro Ala Ser Val Ala Asn Thr Trp
             100                 105                 110

 cga agg gca agg agc ctc gcc cag aga ttt cac ggg gct cag gtg aga      384
 Arg Arg Ala Arg Ser Leu Ala Gln Arg Phe His Gly Ala Gln Val Arg
         115                 120                 125

 agc agt aag aag agc ctg caa acg agt gct ccc ggt tcc agg ttt cct      432
 Ser Ser Lys Lys Ser Leu Gln Thr Ser Ala Pro Gly Ser Arg Phe Pro
     130                 135                 140

 ctc cag tac ggc tct cgc ctt aag cag cca gag tga                      468
 Leu Gln Tyr Gly Ser Arg Leu Lys Gln Pro Glu 
 145                 150                 155





      <210> 43
      <211> 786
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(786)

      <400> 43
  atg cat gtt cag ggg aag gca gcc atc ctt gga aga cac ttt tcc atc      48
  Met His Val Gln Gly Lys Ala Ala Ile Leu Gly Arg His Phe Ser Ile
    1               5                  10                  15

 agt tct ctt ctc cca gga gct cta ttg ctg ctc acc gtt atc aaa ggc       96
 Ser Ser Leu Leu Pro Gly Ala Leu Leu Leu Leu Thr Val Ile Lys Gly
              20                  25                  30

 cac act cac cca gag gag aag agt cca ggt gcc cat gag aaa gct gtg      144
 His Thr His Pro Glu Glu Lys Ser Pro Gly Ala His Glu Lys Ala Val
          35                  40                  45

 acg ggt gaa ccc aag tgc ctc ggg gcc ctg ccg tac tgt gat tcc gga      192
 Thr Gly Glu Pro Lys Cys Leu Gly Ala Leu Pro Tyr Cys Asp Ser Gly
      50                  55                  60

 gga aag aag gcc acg aag aag aaa gat gct ggg gaa atg aga tca aga      240
 Gly Lys Lys Ala Thr Lys Lys Lys Asp Ala Gly Glu Met Arg Ser Arg
  65                  70                  75                  80

 ata aag gat ggt gtc ctc gta cta aaa tgt atc agt ctg caa gtc ggc      288
 Ile Lys Asp Gly Val Leu Val Leu Lys Cys Ile Ser Leu Gln Val Gly
                  85                  90                  95

 ctt gcc tcc tgg att gtg agt tgg ctg agg acc gag gcc aca gga tac      336
 Leu Ala Ser Trp Ile Val Ser Trp Leu Arg Thr Glu Ala Thr Gly Tyr
             100                 105                 110

 acc ttt gct ctc ctg cct cct ggc acc cat cac acg gag cag acc ccc      384
 Thr Phe Ala Leu Leu Pro Pro Gly Thr His His Thr Glu Gln Thr Pro
         115                 120                 125

 agt aaa cat gag caa aat gga gct gaa ttg ttc tgc aac tgc gtg tct      432
 Ser Lys His Glu Gln Asn Gly Ala Glu Leu Phe Cys Asn Cys Val Ser
     130                 135                 140

 tgc ttt gaa gac ccc tgt ccc tgc cag gtg cct ggg aca cag cca gga      480
 Cys Phe Glu Asp Pro Cys Pro Cys Gln Val Pro Gly Thr Gln Pro Gly
 145                 150                 155                 160

 aac cgc ctc tct gag gag cac cag gcc tct tcc cag gct gac gtg acc      528
 Asn Arg Leu Ser Glu Glu His Gln Ala Ser Ser Gln Ala Asp Val Thr
                 165                 170                 175

 aac tcg tct gcc cct aaa caa ccg cac cca cca ccg gca cca tgc aag      576
 Asn Ser Ser Ala Pro Lys Gln Pro His Pro Pro Pro Ala Pro Cys Lys
             180                 185                 190

 gtg tct gtt cac att gct gag ctg ggc gag atc gtc tgt cag tca tta      624
 Val Ser Val His Ile Ala Glu Leu Gly Glu Ile Val Cys Gln Ser Leu
         195                 200                 205

 cat aaa aca gga gcc agt gac ctt tgc gaa gta cac aag gtg gaa gtc      672
 His Lys Thr Gly Ala Ser Asp Leu Cys Glu Val His Lys Val Glu Val
     210                 215                 220

 atg agc gaa aga gat cat gaa cgc ttc aaa tat ggc tac gga gtt ata      720
 Met Ser Glu Arg Asp His Glu Arg Phe Lys Tyr Gly Tyr Gly Val Ile
 225                 230                 235                 240

 agc gtc atc acc aac tca ctg aag att aag gaa tct ggg aac aaa tta      768
 Ser Val Ile Thr Asn Ser Leu Lys Ile Lys Glu Ser Gly Asn Lys Leu
                 245                 250                 255

 gcc tgt tgt aga cag tga                                              786
 Ala Cys Cys Arg Gln 
             260





      <210> 44
      <211> 585
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(585)

      <400> 44
  atg agc tta ttg caa gtt aag tct cca acg tgg ttc aga aag gcc atc      48
  Met Ser Leu Leu Gln Val Lys Ser Pro Thr Trp Phe Arg Lys Ala Ile
    1               5                  10                  15

 tgc ctt ctg ctc aga tct gct gct cat ggg ttg agt gct cct gac agg       96
 Cys Leu Leu Leu Arg Ser Ala Ala His Gly Leu Ser Ala Pro Asp Arg
              20                  25                  30

 tac aca agt ctt cca ctc caa agc cca gac cag gag agg ggt ggc ttc      144
 Tyr Thr Ser Leu Pro Leu Gln Ser Pro Asp Gln Glu Arg Gly Gly Phe
          35                  40                  45

 acc agt gga ggg cac cag ggc tct gtg atg agc cgg gaa ctg gaa tgc      192
 Thr Ser Gly Gly His Gln Gly Ser Val Met Ser Arg Glu Leu Glu Cys
      50                  55                  60

 ggc cac cta ggc aga agt gga ggt gat gga gat act gag tgg cag gga      240
 Gly His Leu Gly Arg Ser Gly Gly Asp Gly Asp Thr Glu Trp Gln Gly
  65                  70                  75                  80

 gag atc tcc cat cca aat agc ata act ctg cca gcc caa tca ccc tta      288
 Glu Ile Ser His Pro Asn Ser Ile Thr Leu Pro Ala Gln Ser Pro Leu
                  85                  90                  95

 aaa cca ttt tca tca ctt ttc aca ggg ata atg att cat agc aac att      336
 Lys Pro Phe Ser Ser Leu Phe Thr Gly Ile Met Ile His Ser Asn Ile
             100                 105                 110

 caa ctc aca cag cca ttt aaa aat gta aaa atc att ctt ggt tca gag      384
 Gln Leu Thr Gln Pro Phe Lys Asn Val Lys Ile Ile Leu Gly Ser Glu
         115                 120                 125

 gct gta caa aaa cag gga gta ggc tgc ttt tcc tgt ggg ctg tcg tgt      432
 Ala Val Gln Lys Gln Gly Val Gly Cys Phe Ser Cys Gly Leu Ser Cys
     130                 135                 140

 gga gac ctc tat gct aag cac aga ctt tcc ctt agt tca gct gca aga      480
 Gly Asp Leu Tyr Ala Lys His Arg Leu Ser Leu Ser Ser Ala Ala Arg
 145                 150                 155                 160

 tct ccg gac cct cag cag acc tcc ttc cct gtt cct gtt aca gga ctt      528
 Ser Pro Asp Pro Gln Gln Thr Ser Phe Pro Val Pro Val Thr Gly Leu
                 165                 170                 175

 tcc ctt agt tca gcc aac cac ggg gtc ctt gtc cgt ccc acg gcc acg      576
 Ser Leu Ser Ser Ala Asn His Gly Val Leu Val Arg Pro Thr Ala Thr
             180                 185                 190

 aaa atg tag                                                          585
 Lys Met 






      <210> 45
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 45
  atg agc agg aag gtg gtg ttg gtc acg tcc acg ctc ctg ctc atc tct      48
  Met Ser Arg Lys Val Val Leu Val Thr Ser Thr Leu Leu Leu Ile Ser
    1               5                  10                  15

 cgg tcc agc tcg gcc acg atg ctg tcc ctg caa gac aga gat gct cac       96
 Arg Ser Ser Ser Ala Thr Met Leu Ser Leu Gln Asp Arg Asp Ala His
              20                  25                  30

 gac cca cag ctg ggg tgg cct ctg tgg gac ctc aga ggg tcc cct tcc      144
 Asp Pro Gln Leu Gly Trp Pro Leu Trp Asp Leu Arg Gly Ser Pro Ser
          35                  40                  45

 ttg gaa gca gac agg tcc aga gag gcc agt gat ctg acc gca ctg ggc      192
 Leu Glu Ala Asp Arg Ser Arg Glu Ala Ser Asp Leu Thr Ala Leu Gly
      50                  55                  60

 cgt cag caa ctc aag gcc tat gag ctg ctt caa ccc caa cag ctg ggc      240
 Arg Gln Gln Leu Lys Ala Tyr Glu Leu Leu Gln Pro Gln Gln Leu Gly
  65                  70                  75                  80

 ggt gcc tgc cat ctt gtg ggc aaa ctg gca aat gtc aga aac cca gaa      288
 Gly Ala Cys His Leu Val Gly Lys Leu Ala Asn Val Arg Asn Pro Glu
                  85                  90                  95

 acg tca tga                                                          297
 Thr Ser 






      <210> 46
      <211> 600
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(600)

      <400> 46
  atg gca aag ggt tgg cct cat tgt tta cgg gta gtg gca gca gta gta      48
  Met Ala Lys Gly Trp Pro His Cys Leu Arg Val Val Ala Ala Val Val
    1               5                  10                  15

 gtc tta gta tct gaa gca gtt aaa cta ata cag gga aga gat ctt act       96
 Val Leu Val Ser Glu Ala Val Lys Leu Ile Gln Gly Arg Asp Leu Thr
              20                  25                  30

 gtg tgg aca tct cat gat gtg aat ggc ata ctc act gct aaa gga gac      144
 Val Trp Thr Ser His Asp Val Asn Gly Ile Leu Thr Ala Lys Gly Asp
          35                  40                  45

 ttg tgg ctg tca gac aac cat tta ctt aaa tat cag gct cta tta ctt      192
 Leu Trp Leu Ser Asp Asn His Leu Leu Lys Tyr Gln Ala Leu Leu Leu
      50                  55                  60

 gaa ggg cca gtg ctg cga ctg tgc act tgt gca act ctt aac cca gcc      240
 Glu Gly Pro Val Leu Arg Leu Cys Thr Cys Ala Thr Leu Asn Pro Ala
  65                  70                  75                  80

 aca ttt ctt cca gac aat aaa gaa aag ata gaa cat aac tgt cag caa      288
 Thr Phe Leu Pro Asp Asn Lys Glu Lys Ile Glu His Asn Cys Gln Gln
                  85                  90                  95

 gta att gtt caa acc tac gct gct caa ggg gat cct tta gag gtt ccc      336
 Val Ile Val Gln Thr Tyr Ala Ala Gln Gly Asp Pro Leu Glu Val Pro
             100                 105                 110

 ttg act gat cct gac ctc acc tta tgt act gat gga agt tcc ttt gta      384
 Leu Thr Asp Pro Asp Leu Thr Leu Cys Thr Asp Gly Ser Ser Phe Val
         115                 120                 125

 gaa aaa gga ctt cga aaa gtg gga atc aaa gct gta aaa cta caa atc      432
 Glu Lys Gly Leu Arg Lys Val Gly Ile Lys Ala Val Lys Leu Gln Ile
     130                 135                 140

 att ctt caa atg gag cca cag atg ccg tcc atg act aag agc tac cgt      480
 Ile Leu Gln Met Glu Pro Gln Met Pro Ser Met Thr Lys Ser Tyr Arg
 145                 150                 155                 160

 gga cca ttg gac cgg cct gct agc cca tgc tcc aat gtt aat gac atc      528
 Gly Pro Leu Asp Arg Pro Ala Ser Pro Cys Ser Asn Val Asn Asp Ile
                 165                 170                 175

 gaa ggc acc cct cct gag gaa atc tca act gca caa ccc cta cta tgc      576
 Glu Gly Thr Pro Pro Glu Glu Ile Ser Thr Ala Gln Pro Leu Leu Cys
             180                 185                 190

 ccc aat tca gga gga agc agt tag                                      600
 Pro Asn Ser Gly Gly Ser Ser 
         195





      <210> 47
      <211> 138
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(138)

      <400> 47
  atg ctc tgc ctg cct gca gtg ctg cca gga gcg ttg ctg cct ctg gtc      48
  Met Leu Cys Leu Pro Ala Val Leu Pro Gly Ala Leu Leu Pro Leu Val
    1               5                  10                  15

 tgg cca ttt gca gaa tgc aca ggt gaa ttt gga gca gct gca gac agt       96
 Trp Pro Phe Ala Glu Cys Thr Gly Glu Phe Gly Ala Ala Ala Asp Ser
              20                  25                  30

 gga gat gta gcc agg gct gct ggc tac cag cag tgt cgc tga              138
 Gly Asp Val Ala Arg Ala Ala Gly Tyr Gln Gln Cys Arg 
          35                  40                  45





      <210> 48
      <211> 1137
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1137)

      <400> 48
  atg agg agc ctg ccg agc ctg ggc ggc ctc gcc ctg ttg tgc tgc gcc      48
  Met Arg Ser Leu Pro Ser Leu Gly Gly Leu Ala Leu Leu Cys Cys Ala
    1               5                  10                  15

 gcc gcc gcc gcc gcc gcc gcc gtc gcc tca gcc gcc tcg gcg ggg aat       96
 Ala Ala Ala Ala Ala Ala Ala Val Ala Ser Ala Ala Ser Ala Gly Asn
              20                  25                  30

 gtc acc ggt ggc ggc ggg gcc gcg ggg cag ggc gac ggc tcc cac ggc      144
 Val Thr Gly Gly Gly Gly Ala Ala Gly Gln Gly Asp Gly Ser His Gly
          35                  40                  45

 cca ggc ccc gag gac cgg gcc ccc gcg cgc cac cgt cca ccg acc cct      192
 Pro Gly Pro Glu Asp Arg Ala Pro Ala Arg His Arg Pro Pro Thr Pro
      50                  55                  60

 ggc tgc gac ttc tcc agc cca gtc ccc gga gac cac ccc tct ttg ggc      240
 Gly Cys Asp Phe Ser Ser Pro Val Pro Gly Asp His Pro Ser Leu Gly
  65                  70                  75                  80

 gac tgc tgg acc ctc ttc cac cac ctt tca ggc gcc gct cgg ccc ctc      288
 Asp Cys Trp Thr Leu Phe His His Leu Ser Gly Ala Ala Arg Pro Leu
                  85                  90                  95

 gcc gac cac ccc tcc ggc ggc gga acg cac ttc gac cac ctc tca ggc      336
 Ala Asp His Pro Ser Gly Gly Gly Thr His Phe Asp His Leu Ser Gly
             100                 105                 110

 gcc gac cag acc cgc gcc gac cac cct ttc gac gac cac tgg ccc ggc      384
 Ala Asp Gln Thr Arg Ala Asp His Pro Phe Asp Asp His Trp Pro Gly
         115                 120                 125

 gcc gac cac ccc tgt agc gac cac cgt acc ggc gcc cac gac tcc ccg      432
 Ala Asp His Pro Cys Ser Asp His Arg Thr Gly Ala His Asp Ser Pro
     130                 135                 140

 gac ccc gac ccc cga tct ccc cag cag cag caa cag cag cgt cct ccc      480
 Asp Pro Asp Pro Arg Ser Pro Gln Gln Gln Gln Gln Gln Arg Pro Pro
 145                 150                 155                 160

 cac ccc acc tgc cac cga ggc ccc ctc ttc gcc tcc tcc aga atg gcc      528
 His Pro Thr Cys His Arg Gly Pro Leu Phe Ala Ser Ser Arg Met Ala
                 165                 170                 175

 cag gtc aag cta gaa tta tcc tgt gtc atg ttg cca gtt aca gca gta      576
 Gln Val Lys Leu Glu Leu Ser Cys Val Met Leu Pro Val Thr Ala Val
             180                 185                 190

 atg gta ctg ctc aga act gga cta aat aga aga cat ttt aaa aag gca      624
 Met Val Leu Leu Arg Thr Gly Leu Asn Arg Arg His Phe Lys Lys Ala
         195                 200                 205

 aat gca aag atg gaa atc ccc aaa aca gcc att gtc cag ttc tgg tta      672
 Asn Ala Lys Met Glu Ile Pro Lys Thr Ala Ile Val Gln Phe Trp Leu
     210                 215                 220

 gtt atc tct cag atc aga caa agg agc agc tgt tat tca act ata gat      720
 Val Ile Ser Gln Ile Arg Gln Arg Ser Ser Cys Tyr Ser Thr Ile Asp
 225                 230                 235                 240

 cca act aga ttc gaa tat gtt ttc caa cta gat tac atc cta cag ctg      768
 Pro Thr Arg Phe Glu Tyr Val Phe Gln Leu Asp Tyr Ile Leu Gln Leu
                 245                 250                 255

 aaa agc aag tac ttg cct ctt aca cag cca gtc atg aat ctt aga gtc      816
 Lys Ser Lys Tyr Leu Pro Leu Thr Gln Pro Val Met Asn Leu Arg Val
             260                 265                 270

 tca gaa gct gtt aaa acg ggt aga aaa att gtt atg gga agg gag agg      864
 Ser Glu Ala Val Lys Thr Gly Arg Lys Ile Val Met Gly Arg Glu Arg
         275                 280                 285

 atg aaa att gtt atc agg tct aaa atg tca ggt tac agt cag att tgg      912
 Met Lys Ile Val Ile Arg Ser Lys Met Ser Gly Tyr Ser Gln Ile Trp
     290                 295                 300

 caa tgt gta tta ctt caa atg att gag ctg gag gaa act aca ttc ctt      960
 Gln Cys Val Leu Leu Gln Met Ile Glu Leu Glu Glu Thr Thr Phe Leu
 305                 310                 315                 320

 tgg aat gat gac aga atc tat cag aaa ctt cac aca tcc act cag ctc     1008
 Trp Asn Asp Asp Arg Ile Tyr Gln Lys Leu His Thr Ser Thr Gln Leu
                 325                 330                 335

 tcc tgg atc cct gtc cac acc atg aag cct gaa gtt gtt atg atg gcc     1056
 Ser Trp Ile Pro Val His Thr Met Lys Pro Glu Val Val Met Met Ala
             340                 345                 350

 ttt atg aac ctg aaa gaa gcc gct ggc ttc cac cac acc aca gtg tca     1104
 Phe Met Asn Leu Lys Glu Ala Ala Gly Phe His His Thr Thr Val Ser
         355                 360                 365

 ccc aag aaa tcc aat cct tgt aag aaa gga tag                         1137
 Pro Lys Lys Ser Asn Pro Cys Lys Lys Gly 
     370                 375





      <210> 49
      <211> 246
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(246)

      <400> 49
  atg gtc agc gct gcc cag ggg cag gct ctg tac ctg ctg ctg tgt gcc      48
  Met Val Ser Ala Ala Gln Gly Gln Ala Leu Tyr Leu Leu Leu Cys Ala
    1               5                  10                  15

 aga gaa ttc cac acg gcc aca gta cag tcc aga aac cag cca gaa cca       96
 Arg Glu Phe His Thr Ala Thr Val Gln Ser Arg Asn Gln Pro Glu Pro
              20                  25                  30

 gcc cat ggg gtc aac tac tcg gtg aaa aca gag gcc cat tcc aca ggc      144
 Ala His Gly Val Asn Tyr Ser Val Lys Thr Glu Ala His Ser Thr Gly
          35                  40                  45

 acc act gct gag cct ctg agt tcc cag gac agg gct gtc cga gga cac      192
 Thr Thr Ala Glu Pro Leu Ser Ser Gln Asp Arg Ala Val Arg Gly His
      50                  55                  60

 aac act gac agc cat gtg cag acc ccc gac ctg ggc gag gat acc gcc      240
 Asn Thr Asp Ser His Val Gln Thr Pro Asp Leu Gly Glu Asp Thr Ala
  65                  70                  75                  80

 ctc tga                                                              246
 Leu 






      <210> 50
      <211> 300
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(300)

      <400> 50
  atg ctg cac aca ctg gag ctt ttg ttt ctg ttg aag atc aat cca ctg      48
  Met Leu His Thr Leu Glu Leu Leu Phe Leu Leu Lys Ile Asn Pro Leu
    1               5                  10                  15

 ctc agt ttc ttc ttc ctg cag ctg gtt gag ttc ttt cca gac aaa gac       96
 Leu Ser Phe Phe Phe Leu Gln Leu Val Glu Phe Phe Pro Asp Lys Asp
              20                  25                  30

 aag ggt gag acg agt gaa ggt gga gca gag tcc ttc agt tcc gag tct      144
 Lys Gly Glu Thr Ser Glu Gly Gly Ala Glu Ser Phe Ser Ser Glu Ser
          35                  40                  45

 cca gga gag aac cag ctc tac tct gag atg cag ttt ttc tac ctc tgt      192
 Pro Gly Glu Asn Gln Leu Tyr Ser Glu Met Gln Phe Phe Tyr Leu Cys
      50                  55                  60

 gaa caa cgt gca gtg gtt cca aca gaa tcc tgg gtt ggc ctc atc aat      240
 Glu Gln Arg Ala Val Val Pro Thr Glu Ser Trp Val Gly Leu Ile Asn
  65                  70                  75                  80

 ctg ttt ttc atg gct tca tgg atg aag cac agt gga aag tta tgg tca      288
 Leu Phe Phe Met Ala Ser Trp Met Lys His Ser Gly Lys Leu Trp Ser
                  85                  90                  95

 aaa aga aac tga                                                      300
 Lys Arg Asn 






      <210> 51
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 51
  atg gtg ttg atg tgt gga gtc cgg tgc ctg gtt tgg gga atg ttc atg      48
  Met Val Leu Met Cys Gly Val Arg Cys Leu Val Trp Gly Met Phe Met
    1               5                  10                  15

 gga tat gtt cca aag gac tta cgg acc tat cag gta ctg gag tat ctg       96
 Gly Tyr Val Pro Lys Asp Leu Arg Thr Tyr Gln Val Leu Glu Tyr Leu
              20                  25                  30

 agc agc tcc tgt gtg cca gct gct ggt cta caa gat gga tgg gtc ctt      144
 Ser Ser Ser Cys Val Pro Ala Ala Gly Leu Gln Asp Gly Trp Val Leu
          35                  40                  45

 gga gat cac gct gta gca gag gag gca ggc tac agc cca cag gcc aga      192
 Gly Asp His Ala Val Ala Glu Glu Ala Gly Tyr Ser Pro Gln Ala Arg
      50                  55                  60

 gac agc ccc ctg cct gtt cat aca aat aaa gtt tta ttg gaa cac agc      240
 Asp Ser Pro Leu Pro Val His Thr Asn Lys Val Leu Leu Glu His Ser
  65                  70                  75                  80

 cac acc tat ttc agt gca tat tgt ctg tgg ctg ctt tcc tgc tac att      288
 His Thr Tyr Phe Ser Ala Tyr Cys Leu Trp Leu Leu Ser Cys Tyr Ile
                  85                  90                  95

 gga gag ttg aat agt tgc gac aga gac cta tgg cct gca atg ctg aac      336
 Gly Glu Leu Asn Ser Cys Asp Arg Asp Leu Trp Pro Ala Met Leu Asn
             100                 105                 110

 tat tta cca tct ggc cct cga gag aaa caa aaa aaa tgc tga              378
 Tyr Leu Pro Ser Gly Pro Arg Glu Lys Gln Lys Lys Cys 
         115                 120                 125





      <210> 52
      <211> 132
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(132)

      <400> 52
  atg cag aaa att tgg acc cct gat aca ttg ctg agc tat ctg cag gtg      48
  Met Gln Lys Ile Trp Thr Pro Asp Thr Leu Leu Ser Tyr Leu Gln Val
    1               5                  10                  15

 ctc ctg tgt tca gtc ctt cca aac cat ttt ctg aag aat atc tac ctg       96
 Leu Leu Cys Ser Val Leu Pro Asn His Phe Leu Lys Asn Ile Tyr Leu
              20                  25                  30

 tgc aca aaa cac act cgc agt gct cag ccc cac tga                      132
 Cys Thr Lys His Thr Arg Ser Ala Gln Pro His 
          35                  40





      <210> 53
      <211> 348
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(348)

      <400> 53
  atg gcc ctt tcc ctc ttt gca gtt cag tct aag tct cgt att tgc ttt      48
  Met Ala Leu Ser Leu Phe Ala Val Gln Ser Lys Ser Arg Ile Cys Phe
    1               5                  10                  15

 gct gtc tgt gtg ctg aag ctc gtc ccg tgt gag ttg ctg tct gcc cct       96
 Ala Val Cys Val Leu Lys Leu Val Pro Cys Glu Leu Leu Ser Ala Pro
              20                  25                  30

 tgt cag gct gtg agt gga ggc gtc tcg ctg tgt gaa gat gcc gtg ttc      144
 Cys Gln Ala Val Ser Gly Gly Val Ser Leu Cys Glu Asp Ala Val Phe
          35                  40                  45

 tca gat ggg ctc agc tgt cag cgt gtg gcc agc gtt agg ttg agc ttc      192
 Ser Asp Gly Leu Ser Cys Gln Arg Val Ala Ser Val Arg Leu Ser Phe
      50                  55                  60

 ctg ctg ctt aga aac cca aga gct cgg cga gct gtg tct gct gga gat      240
 Leu Leu Leu Arg Asn Pro Arg Ala Arg Arg Ala Val Ser Ala Gly Asp
  65                  70                  75                  80

 tgg tgc agt gaa gca gca ggg atc aag tta gcc tgg gca gct gct gtg      288
 Trp Cys Ser Glu Ala Ala Gly Ile Lys Leu Ala Trp Ala Ala Ala Val
                  85                  90                  95

 gga tct gag tgc agc atc ccc aga gga gcc gct cca gct gca gat gac      336
 Gly Ser Glu Cys Ser Ile Pro Arg Gly Ala Ala Pro Ala Ala Asp Asp
             100                 105                 110

 atg ggg cct tga                                                      348
 Met Gly Pro 
         115





      <210> 54
      <211> 903
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(903)

      <400> 54
  atg ccg ggc cgg ctg cta ctt aca ctg ctc cgc ttt ggt gga cat ggt      48
  Met Pro Gly Arg Leu Leu Leu Thr Leu Leu Arg Phe Gly Gly His Gly
    1               5                  10                  15

 gct gtc cag ttg gaa agg ctt tgc ccc aaa atc tgt gtc gtg ccc gtg       96
 Ala Val Gln Leu Glu Arg Leu Cys Pro Lys Ile Cys Val Val Pro Val
              20                  25                  30

 tcg cta cca ttc gga caa aac gca cat caa att gca gaa ttc ggt ccc      144
 Ser Leu Pro Phe Gly Gln Asn Ala His Gln Ile Ala Glu Phe Gly Pro
          35                  40                  45

 gga agg tta gga aat cgc ccc cgg aga aat ggg tgg gat tta ata ggc      192
 Gly Arg Leu Gly Asn Arg Pro Arg Arg Asn Gly Trp Asp Leu Ile Gly
      50                  55                  60

 ggc caa agg ctt cct gtc cgt ccc ctc ctg gag ctg ccc gcg ttg atg      240
 Gly Gln Arg Leu Pro Val Arg Pro Leu Leu Glu Leu Pro Ala Leu Met
  65                  70                  75                  80

 tgg gcg ggg aga ccg aaa gga gag agc agg ctg cgg ctc ctg gtg aaa      288
 Trp Ala Gly Arg Pro Lys Gly Glu Ser Arg Leu Arg Leu Leu Val Lys
                  85                  90                  95

 tgg gaa aat ggg ctc gac cgg ggg agg agt att tcc att cat aag gcg      336
 Trp Glu Asn Gly Leu Asp Arg Gly Arg Ser Ile Ser Ile His Lys Ala
             100                 105                 110

 cac gga ggg gac ggg tgt ttc cca gag aaa agc ctc tta aag cgc cgg      384
 His Gly Gly Asp Gly Cys Phe Pro Glu Lys Ser Leu Leu Lys Arg Arg
         115                 120                 125

 agt ccc cga cca ttt gga tct ccc att ggc gtt ctc cgg gcc tgt aaa      432
 Ser Pro Arg Pro Phe Gly Ser Pro Ile Gly Val Leu Arg Ala Cys Lys
     130                 135                 140

 tcc tgc tcc cgg agc agc ccc cgg agc ctc agc agg gtg acc aga gag      480
 Ser Cys Ser Arg Ser Ser Pro Arg Ser Leu Ser Arg Val Thr Arg Glu
 145                 150                 155                 160

 gga ccc agg ggt atc ttg tta agg aaa act ttt cag tgt ctt aaa gat      528
 Gly Pro Arg Gly Ile Leu Leu Arg Lys Thr Phe Gln Cys Leu Lys Asp
                 165                 170                 175

 tat ttt tta acc tac tac aca agt agc aag gtg gtg cct gta aaa gta      576
 Tyr Phe Leu Thr Tyr Tyr Thr Ser Ser Lys Val Val Pro Val Lys Val
             180                 185                 190

 cca tgc aga caa gtg ctt acg ata gac aag tgc tca ctg cca aga agc      624
 Pro Cys Arg Gln Val Leu Thr Ile Asp Lys Cys Ser Leu Pro Arg Ser
         195                 200                 205

 agc cac cgg aat gcc agg act gtc agc aat gac ttt ccg cgg aag agt      672
 Ser His Arg Asn Ala Arg Thr Val Ser Asn Asp Phe Pro Arg Lys Ser
     210                 215                 220

 tgt tct cga gaa aga tgc act cat tgc atg cga cca ccc gag gga cgc      720
 Cys Ser Arg Glu Arg Cys Thr His Cys Met Arg Pro Pro Glu Gly Arg
 225                 230                 235                 240

 cgg ccg ccg aac gga aac atg aat tcg tgg aaa tgg cca tct ggt gac      768
 Arg Pro Pro Asn Gly Asn Met Asn Ser Trp Lys Trp Pro Ser Gly Asp
                 245                 250                 255

 gta gta gtg aca cag ttc tta tat tct gat aca ttt aat aat gtg tca      816
 Val Val Val Thr Gln Phe Leu Tyr Ser Asp Thr Phe Asn Asn Val Ser
             260                 265                 270

 caa ttc gct gga cta agc agg atg ctg cca caa gag gca aac tcc cag      864
 Gln Phe Ala Gly Leu Ser Arg Met Leu Pro Gln Glu Ala Asn Ser Gln
         275                 280                 285

 cga ccc gac gcc cgg ctc cca gcc gac gag caa aaa taa                  903
 Arg Pro Asp Ala Arg Leu Pro Ala Asp Glu Gln Lys 
     290                 295                 300





      <210> 55
      <211> 1143
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1143)

      <400> 55
  atg gcc gtc atg atc atc acc atc atc tct gtt ctc agc tgt gat ggc      48
  Met Ala Val Met Ile Ile Thr Ile Ile Ser Val Leu Ser Cys Asp Gly
    1               5                  10                  15

 ctt tct ttc acg ctg gac aag gga ggg ccc cag atg gag aag ggg cac       96
 Leu Ser Phe Thr Leu Asp Lys Gly Gly Pro Gln Met Glu Lys Gly His
              20                  25                  30

 cag aga cac gtt gca agg gga ggg aaa caa gcc agc aac tct cct aat      144
 Gln Arg His Val Ala Arg Gly Gly Lys Gln Ala Ser Asn Ser Pro Asn
          35                  40                  45

 cat cta ggc acc acc aag tac acc cct tcc aca cac aca ttc ccc ccc      192
 His Leu Gly Thr Thr Lys Tyr Thr Pro Ser Thr His Thr Phe Pro Pro
      50                  55                  60

 aac aac cgc gtt ttt gca att agc agt gtt gca acc aga cag cca tgc      240
 Asn Asn Arg Val Phe Ala Ile Ser Ser Val Ala Thr Arg Gln Pro Cys
  65                  70                  75                  80

 tca acc ggg agg cgg ggg tgg gaa cca ggc atc ata gta ttt aaa tct      288
 Ser Thr Gly Arg Arg Gly Trp Glu Pro Gly Ile Ile Val Phe Lys Ser
                  85                  90                  95

 tgc cag gtg att cca att gca gct aaa gtt gca aac cca gct ttt agc      336
 Cys Gln Val Ile Pro Ile Ala Ala Lys Val Ala Asn Pro Ala Phe Ser
             100                 105                 110

 tgg aaa tcc cca ttt gga agt aca gaa aga aag act cct gtt aaa aag      384
 Trp Lys Ser Pro Phe Gly Ser Thr Glu Arg Lys Thr Pro Val Lys Lys
         115                 120                 125

 ctg gct cct gaa ttt tca aaa gtc aaa aca aaa act cct aag cac tct      432
 Leu Ala Pro Glu Phe Ser Lys Val Lys Thr Lys Thr Pro Lys His Ser
     130                 135                 140

 cct att aaa gag gaa ccc tgt ggt tcc tta tct gaa act gtt tgt aaa      480
 Pro Ile Lys Glu Glu Pro Cys Gly Ser Leu Ser Glu Thr Val Cys Lys
 145                 150                 155                 160

 cgt gaa ttg agg agc caa gaa acc cca gaa aag ccc cgg tct tca gtg      528
 Arg Glu Leu Arg Ser Gln Glu Thr Pro Glu Lys Pro Arg Ser Ser Val
                 165                 170                 175

 gac acc cca cca aga ctc tcc act ccc caa aag gga ccc agc acc cat      576
 Asp Thr Pro Pro Arg Leu Ser Thr Pro Gln Lys Gly Pro Ser Thr His
             180                 185                 190

 ccc aag gag aaa gcc ttc tca agt gag ata gaa gat ttg ccg tac ctt      624
 Pro Lys Glu Lys Ala Phe Ser Ser Glu Ile Glu Asp Leu Pro Tyr Leu
         195                 200                 205

 tcc acc aca gaa atg tat ttg tgt cgt tgg cac cag cct ccc cca tca      672
 Ser Thr Thr Glu Met Tyr Leu Cys Arg Trp His Gln Pro Pro Pro Ser
     210                 215                 220

 ccg tta cca tta cgg gaa tcc tct cca aag aag gag gag act gta gca      720
 Pro Leu Pro Leu Arg Glu Ser Ser Pro Lys Lys Glu Glu Thr Val Ala
 225                 230                 235                 240

 att cct tct tgg agg gac cac tca gta gag cct cta agg gac cca aat      768
 Ile Pro Ser Trp Arg Asp His Ser Val Glu Pro Leu Arg Asp Pro Asn
                 245                 250                 255

 cct tca gac ctt ttg gag aac ctg gat gac agt gtg ttt tcg aag cgg      816
 Pro Ser Asp Leu Leu Glu Asn Leu Asp Asp Ser Val Phe Ser Lys Arg
             260                 265                 270

 cat gca aaa ctg gag ctg gat gag aag aga agg aaa aga tgg gat att      864
 His Ala Lys Leu Glu Leu Asp Glu Lys Arg Arg Lys Arg Trp Asp Ile
         275                 280                 285

 cag agg atc agg gaa caa aga att tta cag cga ctg cag ctc aga atg      912
 Gln Arg Ile Arg Glu Gln Arg Ile Leu Gln Arg Leu Gln Leu Arg Met
     290                 295                 300

 tat aaa aag aaa gga att cag gaa tct gag cct gag gtt acc tca ttt      960
 Tyr Lys Lys Lys Gly Ile Gln Glu Ser Glu Pro Glu Val Thr Ser Phe
 305                 310                 315                 320

 ttc cct gag cca gat gat gtt gaa agt ttg atg att acc ccc ttc ttg     1008
 Phe Pro Glu Pro Asp Asp Val Glu Ser Leu Met Ile Thr Pro Phe Leu
                 325                 330                 335

 cct gtt gta gca ttt gga cga cca tta cca aaa tta act cca cag aat     1056
 Pro Val Val Ala Phe Gly Arg Pro Leu Pro Lys Leu Thr Pro Gln Asn
             340                 345                 350

 ttt gag cta ccc tgg ttg gat gag cgt agc cga tgc aga ttg gag atc     1104
 Phe Glu Leu Pro Trp Leu Asp Glu Arg Ser Arg Cys Arg Leu Glu Ile
         355                 360                 365

 cag aag aag caa aca cct cac cgg acg tgt agg aaa tag                 1143
 Gln Lys Lys Gln Thr Pro His Arg Thr Cys Arg Lys 
     370                 375                 380





      <210> 56
      <211> 420
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(420)

      <400> 56
  atg cct ctg ctg ctg ctg ctg ctg ctg ctg ctg ctg ctg ctg ctg ctg      48
  Met Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu
    1               5                  10                  15

 ctg cgg aac agg gtt gaa gat ccc ttt agc tcc ttg ggt act ttc tct       96
 Leu Arg Asn Arg Val Glu Asp Pro Phe Ser Ser Leu Gly Thr Phe Ser
              20                  25                  30

 agc tcc aag atg gct ttt aag ccc aag atg gag gaa ggc tgg ttg att      144
 Ser Ser Lys Met Ala Phe Lys Pro Lys Met Glu Glu Gly Trp Leu Ile
          35                  40                  45

 att tcc ccc ttg tcg aaa tgg gac cca agg gta gtt cct gag gtg tat      192
 Ile Ser Pro Leu Ser Lys Trp Asp Pro Arg Val Val Pro Glu Val Tyr
      50                  55                  60

 aag aca gga ttt cgg ggt gat aag aca gaa atc caa ggt cac agg aat      240
 Lys Thr Gly Phe Arg Gly Asp Lys Thr Glu Ile Gln Gly His Arg Asn
  65                  70                  75                  80

 gca agg agt cct tac tgt gca ggc ctc cat gat gca ata gcc ctt cat      288
 Ala Arg Ser Pro Tyr Cys Ala Gly Leu His Asp Ala Ile Ala Leu His
                  85                  90                  95

 ggt gct cgt gct ggc cgt gca gaa cct gca ttc aat tgt gag gaa ata      336
 Gly Ala Arg Ala Gly Arg Ala Glu Pro Ala Phe Asn Cys Glu Glu Ile
             100                 105                 110

 cca aca cat caa aca gag gga cat ttt cta aaa cac tgg ctt ctg ccc      384
 Pro Thr His Gln Thr Glu Gly His Phe Leu Lys His Trp Leu Leu Pro
         115                 120                 125

 tac aaa aat gtc aat gtc att ttt gac aaa gac tga                      420
 Tyr Lys Asn Val Asn Val Ile Phe Asp Lys Asp 
     130                 135





      <210> 57
      <211> 564
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(564)

      <400> 57
  atg acg gtg ttg ttc ctg cag gtc tgc tgg ggg agg aca ctg gca ggg      48
  Met Thr Val Leu Phe Leu Gln Val Cys Trp Gly Arg Thr Leu Ala Gly
    1               5                  10                  15

 agg cag gct ctg gag ccg ctg gtg agc gca cag aca cag ccc ctc tcc       96
 Arg Gln Ala Leu Glu Pro Leu Val Ser Ala Gln Thr Gln Pro Leu Ser
              20                  25                  30

 ggg gca ggc act cac agc agc cac aag cac cgc cac ctc gtg gcc tac      144
 Gly Ala Gly Thr His Ser Ser His Lys His Arg His Leu Val Ala Tyr
          35                  40                  45

 agc ccg ctg ctg cca tca gca gga cca atc agt ccc cta ccc acc aga      192
 Ser Pro Leu Leu Pro Ser Ala Gly Pro Ile Ser Pro Leu Pro Thr Arg
      50                  55                  60

 ggc aag gaa cta gca ggc act gct gtg cca ggc ctg ggc tgt ccc tgc      240
 Gly Lys Glu Leu Ala Gly Thr Ala Val Pro Gly Leu Gly Cys Pro Cys
  65                  70                  75                  80

 ctg tca gac agt gag tcc agg gat gcc ctg gac cac cac atc ctc gac      288
 Leu Ser Asp Ser Glu Ser Arg Asp Ala Leu Asp His His Ile Leu Asp
                  85                  90                  95

 agc cct cag ctc aag ggc ata tcc gct ggc ttc tcc cgc cag gaa gga      336
 Ser Pro Gln Leu Lys Gly Ile Ser Ala Gly Phe Ser Arg Gln Glu Gly
             100                 105                 110

 cat gta tct ccc gtg ttt gtg gtg ctg cca gtg cac gta agt aca tac      384
 His Val Ser Pro Val Phe Val Val Leu Pro Val His Val Ser Thr Tyr
         115                 120                 125

 ggt aac atc cta ggc ttc cat gct cac tcg ccc tca ctc cct gag gca      432
 Gly Asn Ile Leu Gly Phe His Ala His Ser Pro Ser Leu Pro Glu Ala
     130                 135                 140

 tcc gag cag ctc ctg gtg cag ggc agg aat aac agc aac atg ctc aat      480
 Ser Glu Gln Leu Leu Val Gln Gly Arg Asn Asn Ser Asn Met Leu Asn
 145                 150                 155                 160

 ttg ggt ctc aag aca cat tca aaa gga gcc ttc ata ggg aaa aac tca      528
 Leu Gly Leu Lys Thr His Ser Lys Gly Ala Phe Ile Gly Lys Asn Ser
                 165                 170                 175

 aca aga ata aaa ctg gaa ccg aat ctg atc att taa                      564
 Thr Arg Ile Lys Leu Glu Pro Asn Leu Ile Ile 
             180                 185





      <210> 58
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 58
  atg cag cag atg gtt tca gcg gcc agc agc tgg gcc ctt cct tgg tca      48
  Met Gln Gln Met Val Ser Ala Ala Ser Ser Trp Ala Leu Pro Trp Ser
    1               5                  10                  15

 gtt agc tcc ctg tta ttg gag atc tgt aag ttt cac cct aaa atc aaa       96
 Val Ser Ser Leu Leu Leu Glu Ile Cys Lys Phe His Pro Lys Ile Lys
              20                  25                  30

 gta gaa cat gct ggc cta tcc att gat gat gtt gcg aaa aaa ctg gga      144
 Val Glu His Ala Gly Leu Ser Ile Asp Asp Val Ala Lys Lys Leu Gly
          35                  40                  45

 gag atg tgg tat gac act gct gca gat gac aag cag cct taa              186
 Glu Met Trp Tyr Asp Thr Ala Ala Asp Asp Lys Gln Pro 
      50                  55                  60





      <210> 59
      <211> 1254
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1254)

      <400> 59
  atg gtg gtg gtg atg gtg atg gtg gtg aga gtg gtg gta gtg gtg atg      48
  Met Val Val Val Met Val Met Val Val Arg Val Val Val Val Val Met
    1               5                  10                  15

 atg gtg gtg gtt ggt gat aat ggt gat ggt ggt gat ggt gag ggg gac       96
 Met Val Val Val Gly Asp Asn Gly Asp Gly Gly Asp Gly Glu Gly Asp
              20                  25                  30

 atg gat ctc cgg ggt cgc tgc gtc ttc ctg acc act gac ggc cag gac      144
 Met Asp Leu Arg Gly Arg Cys Val Phe Leu Thr Thr Asp Gly Gln Asp
          35                  40                  45

 ggc ccc agc ccc cgc ttt acc tgc aag ccc cac tcc agg ctc gag ccc      192
 Gly Pro Ser Pro Arg Phe Thr Cys Lys Pro His Ser Arg Leu Glu Pro
      50                  55                  60

 ccg agg gca ggg ata gct tcc cgg tca tca gac caa acc tgg aga atg      240
 Pro Arg Ala Gly Ile Ala Ser Arg Ser Ser Asp Gln Thr Trp Arg Met
  65                  70                  75                  80

 gta gtg gcc aca gca agg cag atg cca gtt gat ggg aag gaa aac agt      288
 Val Val Ala Thr Ala Arg Gln Met Pro Val Asp Gly Lys Glu Asn Ser
                  85                  90                  95

 gcc att caa aca agg aat gaa ctt gct tgg agc aga aag tac gct ggg      336
 Ala Ile Gln Thr Arg Asn Glu Leu Ala Trp Ser Arg Lys Tyr Ala Gly
             100                 105                 110

 aaa gcc ctt ggt gtt act cca cct cct tca gcg ctc aca cca gtc gcc      384
 Lys Ala Leu Gly Val Thr Pro Pro Pro Ser Ala Leu Thr Pro Val Ala
         115                 120                 125

 ttg att gaa gag cca aag cag ttg gac atc cag tct ctt cct ttt cag      432
 Leu Ile Glu Glu Pro Lys Gln Leu Asp Ile Gln Ser Leu Pro Phe Gln
     130                 135                 140

 ccc atc ctg gac cgg tta aag att aaa gat aag agg cag ctt gtt ccc      480
 Pro Ile Leu Asp Arg Leu Lys Ile Lys Asp Lys Arg Gln Leu Val Pro
 145                 150                 155                 160

 tcc tac ctg gga ggc atg cac acg gtc acc gag ggt ctt gct ggt agg      528
 Ser Tyr Leu Gly Gly Met His Thr Val Thr Glu Gly Leu Ala Gly Arg
                 165                 170                 175

 cag gtt ctg ctc cag cag gtt cag ggt ggg gcc tgg gag tct gca ttt      576
 Gln Val Leu Leu Gln Gln Val Gln Gly Gly Ala Trp Glu Ser Ala Phe
             180                 185                 190

 ctg aca tgc cca tgg gcc atg gct gct gct gct cca ggg ccc aca ctg      624
 Leu Thr Cys Pro Trp Ala Met Ala Ala Ala Ala Pro Gly Pro Thr Leu
         195                 200                 205

 act atg ctg cag ccc agc atc tct gcc gtg ggc ttt tct cag atg gcc      672
 Thr Met Leu Gln Pro Ser Ile Ser Ala Val Gly Phe Ser Gln Met Ala
     210                 215                 220

 atg ggg cca cat gtg cag ggc aga gct agc aaa ctg agc atc tat gta      720
 Met Gly Pro His Val Gln Gly Arg Ala Ser Lys Leu Ser Ile Tyr Val
 225                 230                 235                 240

 aac cca cgc aga cag ctt tcc acc acc acc gcc atg gga gat gaa ctc      768
 Asn Pro Arg Arg Gln Leu Ser Thr Thr Thr Ala Met Gly Asp Glu Leu
                 245                 250                 255

 aat gac ctc tac tgc ggg acc tcc agg cag ctc ttc agc tcc ctg tgc      816
 Asn Asp Leu Tyr Cys Gly Thr Ser Arg Gln Leu Phe Ser Ser Leu Cys
             260                 265                 270

 aac aag aag gaa cct gct gca aag gca gca cct gca gcg cct ctc agt      864
 Asn Lys Lys Glu Pro Ala Ala Lys Ala Ala Pro Ala Ala Pro Leu Ser
         275                 280                 285

 tcg cca ggc ccg cct gct ctg ggc cac gca gga cac gga cgt cag ctt      912
 Ser Pro Gly Pro Pro Ala Leu Gly His Ala Gly His Gly Arg Gln Leu
     290                 295                 300

 ctc ctg gag cgc tcg ctc act tta ttc cat ctc tac gag ctc ctc aag      960
 Leu Leu Glu Arg Ser Leu Thr Leu Phe His Leu Tyr Glu Leu Leu Lys
 305                 310                 315                 320

 tat ccc aga gca tcc cca ggc ctg tgg cca cct cgg gtc tgg atg ccg     1008
 Tyr Pro Arg Ala Ser Pro Gly Leu Trp Pro Pro Arg Val Trp Met Pro
                 325                 330                 335

 cat tct ctg acc tgt ggc aca ttc tgg gtg ccc atg att atg atg agg     1056
 His Ser Leu Thr Cys Gly Thr Phe Trp Val Pro Met Ile Met Met Arg
             340                 345                 350

 ttc tgt gcc cat gtg gcc tca ggg ctc ttg aga cca ccc ttc aac cag     1104
 Phe Cys Ala His Val Ala Ser Gly Leu Leu Arg Pro Pro Phe Asn Gln
         355                 360                 365

 gtc ttt gct cac ctg tct cct gcc cag gga cgc cac cca ggt gaa aat     1152
 Val Phe Ala His Leu Ser Pro Ala Gln Gly Arg His Pro Gly Glu Asn
     370                 375                 380

 ggg atc atc gtg ctg acc tca agg gca gct gta gga ttc gat gtt cct     1200
 Gly Ile Ile Val Leu Thr Ser Arg Ala Ala Val Gly Phe Asp Val Pro
 385                 390                 395                 400

 cat gtc acg gtc tct aac cgt gtg gca cat tct ggg tgc cca tgg tta     1248
 His Val Thr Val Ser Asn Arg Val Ala His Ser Gly Cys Pro Trp Leu
                 405                 410                 415

 cga tga                                                             1254
 Arg 






      <210> 60
      <211> 339
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(339)

      <400> 60
  atg agc cag ctc tca ctc ttg gtg aga gct gtg gtc aag ctc ctc cag      48
  Met Ser Gln Leu Ser Leu Leu Val Arg Ala Val Val Lys Leu Leu Gln
    1               5                  10                  15

 cct ctt ccc cac ttt tgg gag gct ttc tgg gca gtg gcc aag gct ttg       96
 Pro Leu Pro His Phe Trp Glu Ala Phe Trp Ala Val Ala Lys Ala Leu
              20                  25                  30

 aaa gat gca gat ctt ggg gcc aag gac cca cat cca gca ggc cta gct      144
 Lys Asp Ala Asp Leu Gly Ala Lys Asp Pro His Pro Ala Gly Leu Ala
          35                  40                  45

 ggc tcc tta gca tgg ccc ccc gac cct ctc ctg ctt ttg ctg gac ccc      192
 Gly Ser Leu Ala Trp Pro Pro Asp Pro Leu Leu Leu Leu Leu Asp Pro
      50                  55                  60

 agt aag cag gac cag tgc tct gcg cac agc acc gcc ctc agg ctg gta      240
 Ser Lys Gln Asp Gln Cys Ser Ala His Ser Thr Ala Leu Arg Leu Val
  65                  70                  75                  80

 cga aat cac ttt tat tca caa tca cag cga ccc aag tgc aca agg gaa      288
 Arg Asn His Phe Tyr Ser Gln Ser Gln Arg Pro Lys Cys Thr Arg Glu
                  85                  90                  95

 gca gca gcc acc cct gca ctg aca gag aac tta gag aac ctg gag gtg      336
 Ala Ala Ala Thr Pro Ala Leu Thr Glu Asn Leu Glu Asn Leu Glu Val
             100                 105                 110

 tga                                                                  339
 






      <210> 61
      <211> 1341
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1341)

      <400> 61
  atg ctc agg cct gcc ccc aca ctg att ttg ttg ctt cat tct ttc ctt      48
  Met Leu Arg Pro Ala Pro Thr Leu Ile Leu Leu Leu His Ser Phe Leu
    1               5                  10                  15

 gct ttg ttt gtg cat ttt gtt caa ttc ttt gtt caa gat gcc aag aac       96
 Ala Leu Phe Val His Phe Val Gln Phe Phe Val Gln Asp Ala Lys Asn
              20                  25                  30

 ttg gct acc ctt cca ctg gca aca gtt gga aca aga aaa aaa gag gag      144
 Leu Ala Thr Leu Pro Leu Ala Thr Val Gly Thr Arg Lys Lys Glu Glu
          35                  40                  45

 cgt gtg acc tta aga atc gat ggg gcc gga ctg gat cct cga gta aat      192
 Arg Val Thr Leu Arg Ile Asp Gly Ala Gly Leu Asp Pro Arg Val Asn
      50                  55                  60

 atc ttg gtt cga gga gag gtt tac aaa tgc tct cct gag cca gtg ttt      240
 Ile Leu Val Arg Gly Glu Val Tyr Lys Cys Ser Pro Glu Pro Val Phe
  65                  70                  75                  80

 caa act ttc tat gat gaa cta aat gtg cca gca cca gaa att cca gga      288
 Gln Thr Phe Tyr Asp Glu Leu Asn Val Pro Ala Pro Glu Ile Pro Gly
                  85                  90                  95

 aaa aca aga aat ttg ttt ttg caa tta gcc gag cat ata aca cag tct      336
 Lys Thr Arg Asn Leu Phe Leu Gln Leu Ala Glu His Ile Thr Gln Ser
             100                 105                 110

 ctc aat atc agt tca tgc tgc ttc tgc tgc tgt tct ctc aac cac tgt      384
 Leu Asn Ile Ser Ser Cys Cys Phe Cys Cys Cys Ser Leu Asn His Cys
         115                 120                 125

 gtg ttg ggg gcg ggg ggc cta aaa cca gct gta acc aag tgt cta cgt      432
 Val Leu Gly Ala Gly Gly Leu Lys Pro Ala Val Thr Lys Cys Leu Arg
     130                 135                 140

 acc gga act ggt ctg gct gta acc aag tgt cta cgt acc gga act ggt      480
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
 145                 150                 155                 160

 ctg gct gta acc aag tgt cta cgt acc gga act ggt ctg gct gta acc      528
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
                 165                 170                 175

 aag tgt cta cgt acc gga act ggt ctg gct gta acc aag tgt cta cgt      576
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
             180                 185                 190

 acc gga act ggt ctg gct gta acc aag tgt cta cgt acc gga act ggt      624
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
         195                 200                 205

 ctg gct gta acc aag tgt cta cgt acc gga act ggt ctg gct gta acc      672
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
     210                 215                 220

 aag tgt cta cgt acc gga act ggt ctg gct gta acc aag tgt cta cgt      720
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
 225                 230                 235                 240

 acc gga act ggt ctg gct gta acc aag tgt cta tgt acc gga act ggt      768
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly
                 245                 250                 255

 ctg gct gta acc aag tgt cta tgt acc gga act ggt ctg gct gta acc      816
 Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly Leu Ala Val Thr
             260                 265                 270

 aag tgt cta cgt acc gga act ggt ctg gct gta acc aag tgt cta cgt      864
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
         275                 280                 285

 acc gga act ggt ctg gct gta acc aag tgt cta tgt acc gga act ggt      912
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly
     290                 295                 300

 ctg gct gta acc aag tgt cta tgt acc gga act ggt ctg gct gta acc      960
 Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly Leu Ala Val Thr
 305                 310                 315                 320

 aag tgt cta cgt acc gga act ggt ctg gct gta acc aag tgt cta cgt     1008
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
                 325                 330                 335

 acc gga act ggt ctg gct gta acc aag tgt cta cgt acc gga act ggt     1056
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
             340                 345                 350

 ctg gct gta acc aag tgt cta cgt acc gga act ggt ctg gct gta acc     1104
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
         355                 360                 365

 aag tgt cta cgt acc gga act ggt ctg gct gta acc aag tgt cta tgt     1152
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys
     370                 375                 380

 acc gga act ggt ctg gct gta acc aag tgt cta cgt acc gga act ggt     1200
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
 385                 390                 395                 400

 ctg gat tcc ctg gct tac agg tta cct tgt gtc ata cct ttg aaa caa     1248
 Leu Asp Ser Leu Ala Tyr Arg Leu Pro Cys Val Ile Pro Leu Lys Gln
                 405                 410                 415

 ggg acc tgt cca ggc ttc ctt cta atg gcc aac cta cct cta atg ctg     1296
 Gly Thr Cys Pro Gly Phe Leu Leu Met Ala Asn Leu Pro Leu Met Leu
             420                 425                 430

 gcc agt cta tct tac aca aag ttt gaa gtt ttc ctg gtg tca tag         1341
 Ala Ser Leu Ser Tyr Thr Lys Phe Glu Val Phe Leu Val Ser 
         435                 440                 445





      <210> 62
      <211> 234
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(234)

      <400> 62
  atg gcg ttc acg ttc gcg gcc ttc tgc tac atg ctg gcg ctg ctg ctc      48
  Met Ala Phe Thr Phe Ala Ala Phe Cys Tyr Met Leu Ala Leu Leu Leu
    1               5                  10                  15

 act gcc gcg ctc atc ttc ttc gcc att tgg cac cat gat cta tgt ttt       96
 Thr Ala Ala Leu Ile Phe Phe Ala Ile Trp His His Asp Leu Cys Phe
              20                  25                  30

 ggt gag ctc tta gaa caa cac aca gaa gaa ttg gtc cag tta agt gca      144
 Gly Glu Leu Leu Glu Gln His Thr Glu Glu Leu Val Gln Leu Ser Ala
          35                  40                  45

 tgc aaa aag cca cca aat gaa ggg att cta tcc agc aag atc ctg tcc      192
 Cys Lys Lys Pro Pro Asn Glu Gly Ile Leu Ser Ser Lys Ile Leu Ser
      50                  55                  60

 aag agt agc ctg tgg aat ctg atc agt tac ttt aaa aaa tga              234
 Lys Ser Ser Leu Trp Asn Leu Ile Ser Tyr Phe Lys Lys 
  65                  70                  75





      <210> 63
      <211> 582
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(582)

      <400> 63
  atg gag ctc tta gta gcc tct aag aca atc atc gtc att ccc acg att      48
  Met Glu Leu Leu Val Ala Ser Lys Thr Ile Ile Val Ile Pro Thr Ile
    1               5                  10                  15

 gcc ttc atc aag gcc aga atg agt gag atg ata ttt cga aga ata aag       96
 Ala Phe Ile Lys Ala Arg Met Ser Glu Met Ile Phe Arg Arg Ile Lys
              20                  25                  30

 atg ccc tgg ctt tgg ctt gat ctc tgg tac ctt atg ttt aaa gaa gga      144
 Met Pro Trp Leu Trp Leu Asp Leu Trp Tyr Leu Met Phe Lys Glu Gly
          35                  40                  45

 tgg gaa cac aaa aag agc ctt cag atc cta cat act ttt acc aac agt      192
 Trp Glu His Lys Lys Ser Leu Gln Ile Leu His Thr Phe Thr Asn Ser
      50                  55                  60

 gtc atc gct gaa cgg gcc aat gaa atg aac gcc aat gaa gac tgt aga      240
 Val Ile Ala Glu Arg Ala Asn Glu Met Asn Ala Asn Glu Asp Cys Arg
  65                  70                  75                  80

 ggt gat ggc agg ggc tct gcc ccc tcc aaa aat aaa cgc agg gcc ttt      288
 Gly Asp Gly Arg Gly Ser Ala Pro Ser Lys Asn Lys Arg Arg Ala Phe
                  85                  90                  95

 ctt gac ttg ctt tta agt gtg act gat gac gaa ggg aac agg cta agt      336
 Leu Asp Leu Leu Leu Ser Val Thr Asp Asp Glu Gly Asn Arg Leu Ser
             100                 105                 110

 cat gaa gat att cga gaa gaa gtt gac acc ttc atg ttt gag gct ggt      384
 His Glu Asp Ile Arg Glu Glu Val Asp Thr Phe Met Phe Glu Ala Gly
         115                 120                 125

 gca ggc tgc aac tgc cca ggt tcc agc tgt gag cta aaa gtg ggc gtc      432
 Ala Gly Cys Asn Cys Pro Gly Ser Ser Cys Glu Leu Lys Val Gly Val
     130                 135                 140

 ctc ccc tgc tcc acc agt gtg cct cgg tgc ttt acg ttt gcc tta tca      480
 Leu Pro Cys Ser Thr Ser Val Pro Arg Cys Phe Thr Phe Ala Leu Ser
 145                 150                 155                 160

 tgc ttt ctg cag ttg gca gat gaa atg aaa tcg gaa gtt cag cag act      528
 Cys Phe Leu Gln Leu Ala Asp Glu Met Lys Ser Glu Val Gln Gln Thr
                 165                 170                 175

 cct ctt atg cat ttg gat cag gct tcc gct cat aaa ttc aag gaa agc      576
 Pro Leu Met His Leu Asp Gln Ala Ser Ala His Lys Phe Lys Glu Ser
             180                 185                 190

 tat taa                                                              582
 Tyr 






      <210> 64
      <211> 207
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(207)

      <400> 64
  atg cct gcg ttc acc tgc acg gcc gtc ttc tgt gtg tca ctg cct gca      48
  Met Pro Ala Phe Thr Cys Thr Ala Val Phe Cys Val Ser Leu Pro Ala
    1               5                  10                  15

 agc ttt aac aag acc tgc aaa agg ccc aag aca gtg gag act gtg cta       96
 Ser Phe Asn Lys Thr Cys Lys Arg Pro Lys Thr Val Glu Thr Val Leu
              20                  25                  30

 gac aag gac cag atg ccc atg gtg aag ctg ctg ctc tgc tca gca agc      144
 Asp Lys Asp Gln Met Pro Met Val Lys Leu Leu Leu Cys Ser Ala Ser
          35                  40                  45

 tgg gaa gca ccc aac gtg gca cac aag gaa tgc tgg gga aat ctg gcc      192
 Trp Glu Ala Pro Asn Val Ala His Lys Glu Cys Trp Gly Asn Leu Ala
      50                  55                  60

 caa gag ctc tcc taa                                                  207
 Gln Glu Leu Ser 
  65





      <210> 65
      <211> 123
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(123)

      <400> 65
  atg acc agg caa agc ctt atg ggc caa ggt atc ttc cct gct ttt ctc      48
  Met Thr Arg Gln Ser Leu Met Gly Gln Gly Ile Phe Pro Ala Phe Leu
    1               5                  10                  15

 acg gtt ctc caa gcc tgg cat act aag gaa gcc tat ggt cac aag ccc       96
 Thr Val Leu Gln Ala Trp His Thr Lys Glu Ala Tyr Gly His Lys Pro
              20                  25                  30

 atg atc aac ctg acc ctc aag ctc tga                                  123
 Met Ile Asn Leu Thr Leu Lys Leu 
          35                  40





      <210> 66
      <211> 573
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(573)

      <400> 66
  atg aac ggc ttc tcg ctg ggt gag ctg tgc tgg ctc ttc tgc tgc ccg      48
  Met Asn Gly Phe Ser Leu Gly Glu Leu Cys Trp Leu Phe Cys Cys Pro
    1               5                  10                  15

 ccc tgc ccg agc cgc atc gcc gcc aag ctg gcc ttc ctg ccg ccc gag       96
 Pro Cys Pro Ser Arg Ile Ala Ala Lys Leu Ala Phe Leu Pro Pro Glu
              20                  25                  30

 ccc acc tac acg gtg ctg gcg ccg gag cag cgc ggc gcc ggc gcg tcc      144
 Pro Thr Tyr Thr Val Leu Ala Pro Glu Gln Arg Gly Ala Gly Ala Ser
          35                  40                  45

 gcc ccg gcc ccg gcc cag gct acc gcc gcc gcc gcc gcg gcc cag ccg      192
 Ala Pro Ala Pro Ala Gln Ala Thr Ala Ala Ala Ala Ala Ala Gln Pro
      50                  55                  60

 gca ccg cag cag ccc gag gag ggc gcg ggc gcg ggg ccc ggt gcg tgc      240
 Ala Pro Gln Gln Pro Glu Glu Gly Ala Gly Ala Gly Pro Gly Ala Cys
  65                  70                  75                  80

 agc ctg cac ctc agc gag cgc gcc gac tgg cag tac tcg cag cgc gag      288
 Ser Leu His Leu Ser Glu Arg Ala Asp Trp Gln Tyr Ser Gln Arg Glu
                  85                  90                  95

 ctg gac gcc gtc gag gtc ttc ttc tcg cgc acg gcc cgg gac aac cgg      336
 Leu Asp Ala Val Glu Val Phe Phe Ser Arg Thr Ala Arg Asp Asn Arg
             100                 105                 110

 ctc ggc tgc atg ttc gtg cgc tgc gcg ccc tcc agc cgc tac acg ctg      384
 Leu Gly Cys Met Phe Val Arg Cys Ala Pro Ser Ser Arg Tyr Thr Leu
         115                 120                 125

 ctc ttc tcg cac ggc aac gcc gtg gac ctg ggc cag atg tgc agc ttc      432
 Leu Phe Ser His Gly Asn Ala Val Asp Leu Gly Gln Met Cys Ser Phe
     130                 135                 140

 tac att ggc ctc ggc tcc cgc atc aac tgc aac atc ttc tcc tac gac      480
 Tyr Ile Gly Leu Gly Ser Arg Ile Asn Cys Asn Ile Phe Ser Tyr Asp
 145                 150                 155                 160

 tac tcg gga tac ggc gtc agc tcg ggc aag ccc tcc gag aag aac ctc      528
 Tyr Ser Gly Tyr Gly Val Ser Ser Gly Lys Pro Ser Glu Lys Asn Leu
                 165                 170                 175

 tac gcc gac atc gac gcc gcg tgg cag gcg ctg cgc acc cgg tga          573
 Tyr Ala Asp Ile Asp Ala Ala Trp Gln Ala Leu Arg Thr Arg 
             180                 185                 190





      <210> 67
      <211> 597
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(597)

      <400> 67
  atg ggc tct ttc ctt gca ctg tca gcc agc agg ctg ctg agg acc ttg      48
  Met Gly Ser Phe Leu Ala Leu Ser Ala Ser Arg Leu Leu Arg Thr Leu
    1               5                  10                  15

 tca atc ttt gaa gac cag tat ttc ttg gtg gat ttt tat gca ccc acc       96
 Ser Ile Phe Glu Asp Gln Tyr Phe Leu Val Asp Phe Tyr Ala Pro Thr
              20                  25                  30

 gca gct gtt gaa agc atg gtg gag cac ttg tct cga gat ata gat gtg      144
 Ala Ala Val Glu Ser Met Val Glu His Leu Ser Arg Asp Ile Asp Val
          35                  40                  45

 att aga ggg aat att gtc aaa cac cct ctg acc cag gaa cta aaa gaa      192
 Ile Arg Gly Asn Ile Val Lys His Pro Leu Thr Gln Glu Leu Lys Glu
      50                  55                  60

 tgt gaa ggg att gtc cca gtc cca ctc gca gaa aaa tta tat tcc aca      240
 Cys Glu Gly Ile Val Pro Val Pro Leu Ala Glu Lys Leu Tyr Ser Thr
  65                  70                  75                  80

 aag aag agg aag aag atg ggt gag gat gag gtc gtt tcc caa aac agt      288
 Lys Lys Arg Lys Lys Met Gly Glu Asp Glu Val Val Ser Gln Asn Ser
                  85                  90                  95

 cac ctg cat ctc ttc ctc ggt ctc ctc ggg gct gat tgg aaa gac ttg      336
 His Leu His Leu Phe Leu Gly Leu Leu Gly Ala Asp Trp Lys Asp Leu
             100                 105                 110

 act agc cct tcc ccc ttc cca ggg ggt gcc ctg cac aag gtg tct gtc      384
 Thr Ser Pro Ser Pro Phe Pro Gly Gly Ala Leu His Lys Val Ser Val
         115                 120                 125

 acc atc aca gat gac gga act tct gca cat aaa atg ttg ggg gaa gtg      432
 Thr Ile Thr Asp Asp Gly Thr Ser Ala His Lys Met Leu Gly Glu Val
     130                 135                 140

 ccg gtt ctg gga atc tct gaa aag cag gaa gga gcc gag agt tct ggc      480
 Pro Val Leu Gly Ile Ser Glu Lys Gln Glu Gly Ala Glu Ser Ser Gly
 145                 150                 155                 160

 ctc tgc ttt gtt ttt aac cat ggc aag acc gga gga tgg aga gat gtg      528
 Leu Cys Phe Val Phe Asn His Gly Lys Thr Gly Gly Trp Arg Asp Val
                 165                 170                 175

 caa gag atg ccc aaa gcg cca gga ggg cct ggt ctc cca gct ctg gcc      576
 Gln Glu Met Pro Lys Ala Pro Gly Gly Pro Gly Leu Pro Ala Leu Ala
             180                 185                 190

 cag cgc ctc ctc cct ctg tag                                          597
 Gln Arg Leu Leu Pro Leu 
         195





      <210> 68
      <211> 345
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(345)

      <400> 68
  atg gac aag tcc ctc ttg ctg gaa ctc ccc atc ctg ctc tgc tgc ttt      48
  Met Asp Lys Ser Leu Leu Leu Glu Leu Pro Ile Leu Leu Cys Cys Phe
    1               5                  10                  15

 agg gca tta tct gga tca ctt tca atg aga aat gat gca gtg ata gaa       96
 Arg Ala Leu Ser Gly Ser Leu Ser Met Arg Asn Asp Ala Val Ile Glu
              20                  25                  30

 att att cag tgt agg atg tgc cac ctc cag ttc cca gga gaa aag tgc      144
 Ile Ile Gln Cys Arg Met Cys His Leu Gln Phe Pro Gly Glu Lys Cys
          35                  40                  45

 tcc aga gga aga gga ata tgc aca gca aca aca gaa gag gcc tgc atg      192
 Ser Arg Gly Arg Gly Ile Cys Thr Ala Thr Thr Glu Glu Ala Cys Met
      50                  55                  60

 gtt gga agg atg ttc aaa agg gat ggt aat ccc tgg tta acc ttc atg      240
 Val Gly Arg Met Phe Lys Arg Asp Gly Asn Pro Trp Leu Thr Phe Met
  65                  70                  75                  80

 ggc tgc cta aag aac tgt gct gat gtg aaa ggc ata agg tgg agt gtc      288
 Gly Cys Leu Lys Asn Cys Ala Asp Val Lys Gly Ile Arg Trp Ser Val
                  85                  90                  95

 tat ttg gtg aac ttc agg tgc tgc agg agc cat gac ctg tgc aat gaa      336
 Tyr Leu Val Asn Phe Arg Cys Cys Arg Ser His Asp Leu Cys Asn Glu
             100                 105                 110

 gac ctt tag                                                          345
 Asp Leu 






      <210> 69
      <211> 1056
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1056)

      <400> 69
  atg gag gct tgt tgt ctt ctg cag ttg ccc caa agg ttg ctc ttg ctg      48
  Met Glu Ala Cys Cys Leu Leu Gln Leu Pro Gln Arg Leu Leu Leu Leu
    1               5                  10                  15

 ggg gca gcc gcc ctg act gca act gct ttg gag aca gcc gac ctg gcg       96
 Gly Ala Ala Ala Leu Thr Ala Thr Ala Leu Glu Thr Ala Asp Leu Ala
              20                  25                  30

 gaa ctg tgc ggg cag acg tgg cag ggg gac ggg ctg ctg ctg cgc tcg      144
 Glu Leu Cys Gly Gln Thr Trp Gln Gly Asp Gly Leu Leu Leu Arg Ser
          35                  40                  45

 cac gcc gca tcg cgc agg ttc tac ttc gtg gct ccg gac acc gac tgc      192
 His Ala Ala Ser Arg Arg Phe Tyr Phe Val Ala Pro Asp Thr Asp Cys
      50                  55                  60

 ggg ctc tgg gtg cag gcg gca gcc ccc ggc gac cgg atc cgc ttc cag      240
 Gly Leu Trp Val Gln Ala Ala Ala Pro Gly Asp Arg Ile Arg Phe Gln
  65                  70                  75                  80

 ttc cgc ttc ttc ctg gtc tac agc ctg acc ccc gcg ccc ccg gcg ctc      288
 Phe Arg Phe Phe Leu Val Tyr Ser Leu Thr Pro Ala Pro Pro Ala Leu
                  85                  90                  95

 aac acc tcc tcc ccg gcc ccg gcc gac ccg tgc gcc ccc ggc tcc tac      336
 Asn Thr Ser Ser Pro Ala Pro Ala Asp Pro Cys Ala Pro Gly Ser Tyr
             100                 105                 110

 ctg cag ttc tac gag ggc ccg ccg ggg gcg ccc cgg ccc ctg ggg tcc      384
 Leu Gln Phe Tyr Glu Gly Pro Pro Gly Ala Pro Arg Pro Leu Gly Ser
         115                 120                 125

 cca ctg tgc ggc ctg aac atc ccg gtg cct gtg gca tcc tcc gga ccc      432
 Pro Leu Cys Gly Leu Asn Ile Pro Val Pro Val Ala Ser Ser Gly Pro
     130                 135                 140

 ttt cta ggc ctg cgc ctg gtc acg aga ggc cgc cag ccc cgc gtg gac      480
 Phe Leu Gly Leu Arg Leu Val Thr Arg Gly Arg Gln Pro Arg Val Asp
 145                 150                 155                 160

 ttc gtg ggc gaa gtc acc tct ttc cgt ctg ggt gag ctg ggg ctg aag      528
 Phe Val Gly Glu Val Thr Ser Phe Arg Leu Gly Glu Leu Gly Leu Lys
                 165                 170                 175

 gcc ggg acg gga ccc tct gca gag gcc atg cgg gac tgg ggc cac agt      576
 Ala Gly Thr Gly Pro Ser Ala Glu Ala Met Arg Asp Trp Gly His Ser
             180                 185                 190

 ggg ggc ccc gga cct tgt ggt gcc tac ttc cgc tgc cag aat ggc agg      624
 Gly Gly Pro Gly Pro Cys Gly Ala Tyr Phe Arg Cys Gln Asn Gly Arg
         195                 200                 205

 tgc atc ccc tca agc ctc gtg tgt gac ccc tgg ggc atg gac aac tgt      672
 Cys Ile Pro Ser Ser Leu Val Cys Asp Pro Trp Gly Met Asp Asn Cys
     210                 215                 220

 ggc gat ggc agt gac cag ggc tcc tgg tca cca gct gac tgc aga ggg      720
 Gly Asp Gly Ser Asp Gln Gly Ser Trp Ser Pro Ala Asp Cys Arg Gly
 225                 230                 235                 240

 cag ggc ccg atg ggg agg cag gag aga gga aag cgg aag tgt gga atc      768
 Gln Gly Pro Met Gly Arg Gln Glu Arg Gly Lys Arg Lys Cys Gly Ile
                 245                 250                 255

 ggc tta ggc caa ggg ctg gag ggg cag agc agt cag ggc cag aac tat      816
 Gly Leu Gly Gln Gly Leu Glu Gly Gln Ser Ser Gln Gly Gln Asn Tyr
             260                 265                 270

 gct gca gat gat ctc atc cgg cgg att cca aat gat gct tta gtg gtg      864
 Ala Ala Asp Asp Leu Ile Arg Arg Ile Pro Asn Asp Ala Leu Val Val
         275                 280                 285

 gaa act ttt gct aaa tgg gac ctg gca tgg agg ccc aag aca ttc aaa      912
 Glu Thr Phe Ala Lys Trp Asp Leu Ala Trp Arg Pro Lys Thr Phe Lys
     290                 295                 300

 gga gat atc ctc tgc tta act gga tgg tgc ctg ggg ccc tgg ctg cct      960
 Gly Asp Ile Leu Cys Leu Thr Gly Trp Cys Leu Gly Pro Trp Leu Pro
 305                 310                 315                 320

 gat gtc tct ctg agg gcc ctg agt gtc acc ctc aag aca tac ttt gaa     1008
 Asp Val Ser Leu Arg Ala Leu Ser Val Thr Leu Lys Thr Tyr Phe Glu
                 325                 330                 335

 aac cat caa tcc agt ctg att ccc aca ctt tac aga tca gga aac tga     1056
 Asn His Gln Ser Ser Leu Ile Pro Thr Leu Tyr Arg Ser Gly Asn 
             340                 345                 350





      <210> 70
      <211> 1128
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1128)

      <400> 70
  atg gag gag gct gct gtc gga atg cag ctg gga ccc atc tcc ctg gca      48
  Met Glu Glu Ala Ala Val Gly Met Gln Leu Gly Pro Ile Ser Leu Ala
    1               5                  10                  15

 ctc tcg agt ctc tgc tta ggg gct ttc cct tcc cag cag gca ctc att       96
 Leu Ser Ser Leu Cys Leu Gly Ala Phe Pro Ser Gln Gln Ala Leu Ile
              20                  25                  30

 cca gga tcc aca ggc acc ttg cgg tcc cca gca ctg ggc ggc act gag      144
 Pro Gly Ser Thr Gly Thr Leu Arg Ser Pro Ala Leu Gly Gly Thr Glu
          35                  40                  45

 ggg gta tca ctg tgg cac cat acc tgc cct tca act ctg aat cca tgt      192
 Gly Val Ser Leu Trp His His Thr Cys Pro Ser Thr Leu Asn Pro Cys
      50                  55                  60

 cag gaa gac cct ggc aag act gag gag gga gag caa atg gta act atg      240
 Gln Glu Asp Pro Gly Lys Thr Glu Glu Gly Glu Gln Met Val Thr Met
  65                  70                  75                  80

 gcc ata act gac aag tgc aca gaa caa gta aag gaa caa agg cag gaa      288
 Ala Ile Thr Asp Lys Cys Thr Glu Gln Val Lys Glu Gln Arg Gln Glu
                  85                  90                  95

 cga gct gag atg gtt cag acc acg ttc act gag agc tgg tgg tgc ttc      336
 Arg Ala Glu Met Val Gln Thr Thr Phe Thr Glu Ser Trp Trp Cys Phe
             100                 105                 110

 aca gcc acc gtc ctt ggg cct ctg gcc tgg tca gta aaa atg ggc tgt      384
 Thr Ala Thr Val Leu Gly Pro Leu Ala Trp Ser Val Lys Met Gly Cys
         115                 120                 125

 gcc cat gga aag tgg cct ctg gct cag ccc tgg aag caa cag ctg gaa      432
 Ala His Gly Lys Trp Pro Leu Ala Gln Pro Trp Lys Gln Gln Leu Glu
     130                 135                 140

 gag gcc tgt ggc ctg tca cta tcc aca cgg ttg ctt ctc tgc aag aca      480
 Glu Ala Cys Gly Leu Ser Leu Ser Thr Arg Leu Leu Leu Cys Lys Thr
 145                 150                 155                 160

 gag gcc cgc cac gat caa atc ctt act cct tca tca gga cct gaa act      528
 Glu Ala Arg His Asp Gln Ile Leu Thr Pro Ser Ser Gly Pro Glu Thr
                 165                 170                 175

 aaa cct gta agc agc ttc ttc cag agc ctt cct ctt ctt ccc cag tcc      576
 Lys Pro Val Ser Ser Phe Phe Gln Ser Leu Pro Leu Leu Pro Gln Ser
             180                 185                 190

 aca cct gca gac ctg ccc ctc acc cgt gcc acc cgc ggt ttg tac agg      624
 Thr Pro Ala Asp Leu Pro Leu Thr Arg Ala Thr Arg Gly Leu Tyr Arg
         195                 200                 205

 aat cag aca aga agg caa ggg ccc gaa ttg gaa gca gat gtt tgg gac      672
 Asn Gln Thr Arg Arg Gln Gly Pro Glu Leu Glu Ala Asp Val Trp Asp
     210                 215                 220

 gat gaa ggt acc aac att gcc act atc cca tgg tta aga agc tgc tgc      720
 Asp Glu Gly Thr Asn Ile Ala Thr Ile Pro Trp Leu Arg Ser Cys Cys
 225                 230                 235                 240

 tgg cta gta ttg aca agt cag ggc tat atc gac agc ctg aac aac tgt      768
 Trp Leu Val Leu Thr Ser Gln Gly Tyr Ile Asp Ser Leu Asn Asn Cys
                 245                 250                 255

 gct aaa gcc acc tct gat acc ata ttg aaa aac cta cag gat cag tct      816
 Ala Lys Ala Thr Ser Asp Thr Ile Leu Lys Asn Leu Gln Asp Gln Ser
             260                 265                 270

 ctg gaa ggc tgc cgg agg gga gaa ttc aga aaa gcg act gcc aaa aac      864
 Leu Glu Gly Cys Arg Arg Gly Glu Phe Arg Lys Ala Thr Ala Lys Asn
         275                 280                 285

 agc aga acc agt cca cgt gcc ccc agc tgg aaa ccc ctt tct ggg ccc      912
 Ser Arg Thr Ser Pro Arg Ala Pro Ser Trp Lys Pro Leu Ser Gly Pro
     290                 295                 300

 aag ggg cag cat tat gtt tcc cag ggt ggt gat aaa cct tcc ggt aca      960
 Lys Gly Gln His Tyr Val Ser Gln Gly Gly Asp Lys Pro Ser Gly Thr
 305                 310                 315                 320

 tat ccc atg gga aaa cat ttg ggc aag cag cag cac ctt gtc ctg gtc     1008
 Tyr Pro Met Gly Lys His Leu Gly Lys Gln Gln His Leu Val Leu Val
                 325                 330                 335

 cct gag gag agc agt gac cat gtg gca tgg agg atc ctg ggg tat aga     1056
 Pro Glu Glu Ser Ser Asp His Val Ala Trp Arg Ile Leu Gly Tyr Arg
             340                 345                 350

 gac cct gat gct gga tcc cgg acc cca agg atg agt gag gtc agc acc     1104
 Asp Pro Asp Ala Gly Ser Arg Thr Pro Arg Met Ser Glu Val Ser Thr
         355                 360                 365

 cat gtg cca aga aag gac aaa tga                                     1128
 His Val Pro Arg Lys Asp Lys 
     370                 375





      <210> 71
      <211> 633
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(633)

      <400> 71
  atg gca gaa gtg aca ctg tgt gac atc caa ggc aag att aga caa ggc      48
  Met Ala Glu Val Thr Leu Cys Asp Ile Gln Gly Lys Ile Arg Gln Gly
    1               5                  10                  15

 atg cag ctg gcc tgg tgg ctt ctc ttg gcc att tgc tct ggg agc ctt       96
 Met Gln Leu Ala Trp Trp Leu Leu Leu Ala Ile Cys Ser Gly Ser Leu
              20                  25                  30

 cag ctg cca tca aag aag ttt ggc ttt cat gaa gaa ggc cac cat atg      144
 Gln Leu Pro Ser Lys Lys Phe Gly Phe His Glu Glu Gly His His Met
          35                  40                  45

 gag aag acc ata caa aga gat cat atg gag aga ttt aaa agc tgt ggg      192
 Glu Lys Thr Ile Gln Arg Asp His Met Glu Arg Phe Lys Ser Cys Gly
      50                  55                  60

 gct gca act agg gag agg caa att tca ata tgg ctt ggc aag gca ctg      240
 Ala Ala Thr Arg Glu Arg Gln Ile Ser Ile Trp Leu Gly Lys Ala Leu
  65                  70                  75                  80

 tta cta ctc ctg gtt gat tgg aaa gga cac aag gac act ttc tgg ggc      288
 Leu Leu Leu Leu Val Asp Trp Lys Gly His Lys Asp Thr Phe Trp Gly
                  85                  90                  95

 aaa cat cca gaa atg tcc tct caa aag aca tca gat ggc tat gga gta      336
 Lys His Pro Glu Met Ser Ser Gln Lys Thr Ser Asp Gly Tyr Gly Val
             100                 105                 110

 aag act tct tta ttc tgg aat gga gga gcc cct gag tgt aat gct ttc      384
 Lys Thr Ser Leu Phe Trp Asn Gly Gly Ala Pro Glu Cys Asn Ala Phe
         115                 120                 125

 tca gaa gtg aag tac aag tca aca aag cct tgc gca gag ctc cca att      432
 Ser Glu Val Lys Tyr Lys Ser Thr Lys Pro Cys Ala Glu Leu Pro Ile
     130                 135                 140

 gta caa gct tca gag ccc ata cat ccg ccc ttg act aag cgg aag aag      480
 Val Gln Ala Ser Glu Pro Ile His Pro Pro Leu Thr Lys Arg Lys Lys
 145                 150                 155                 160

 caa aac caa gag tgt gat tgc atg gaa tta caa gag ggg aaa cca gtg      528
 Gln Asn Gln Glu Cys Asp Cys Met Glu Leu Gln Glu Gly Lys Pro Val
                 165                 170                 175

 gtg agg aat cca ttg cct tcc tgt gat acg ttt cca gag aag atc cga      576
 Val Arg Asn Pro Leu Pro Ser Cys Asp Thr Phe Pro Glu Lys Ile Arg
             180                 185                 190

 ggt att cat gta gta ggt agt aat aga tgg att agg aag aat gtt gta      624
 Gly Ile His Val Val Gly Ser Asn Arg Trp Ile Arg Lys Asn Val Val
         195                 200                 205

 ttg ggt tag                                                          633
 Leu Gly 
     210





      <210> 72
      <211> 1083
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1083)

      <400> 72
  atg ctg agg tct gga gct gtg gct ggg cgg ctg tgg ctg cac ttg gga      48
  Met Leu Arg Ser Gly Ala Val Ala Gly Arg Leu Trp Leu His Leu Gly
    1               5                  10                  15

 gtg agc ctg gct caa ccc gtc agt gat tca agt aag act caa ggt cct       96
 Val Ser Leu Ala Gln Pro Val Ser Asp Ser Ser Lys Thr Gln Gly Pro
              20                  25                  30

 gta gcc aca gag cca gac aag gat caa ggt tct gtg gtc cca ggc ctt      144
 Val Ala Thr Glu Pro Asp Lys Asp Gln Gly Ser Val Val Pro Gly Leu
          35                  40                  45

 ctg aaa ggt caa ggt cct atg gtg caa gag cct ctg aag aag caa gtt      192
 Leu Lys Gly Gln Gly Pro Met Val Gln Glu Pro Leu Lys Lys Gln Val
      50                  55                  60

 tct gtg gtc cca ggg cct cca aag gat cta ggt ccc atg atc cca tta      240
 Ser Val Val Pro Gly Pro Pro Lys Asp Leu Gly Pro Met Ile Pro Leu
  65                  70                  75                  80

 cca gtc aag gat caa gat cac acg gtc cct gag cct tta aag aat gaa      288
 Pro Val Lys Asp Gln Asp His Thr Val Pro Glu Pro Leu Lys Asn Glu
                  85                  90                  95

 agc cac tgt tat ctc agc acc agt caa gga cca agt gcc ctc ggt ccc      336
 Ser His Cys Tyr Leu Ser Thr Ser Gln Gly Pro Ser Ala Leu Gly Pro
             100                 105                 110

 agt tcc tcc aaa gaa tca aag tcc tat gtt tct gct aaa tca cct gtc      384
 Ser Ser Ser Lys Glu Ser Lys Ser Tyr Val Ser Ala Lys Ser Pro Val
         115                 120                 125

 aag gat gaa ggt ccc atg gtc tca gca tct gtc aag gat caa ggt ccc      432
 Lys Asp Glu Gly Pro Met Val Ser Ala Ser Val Lys Asp Gln Gly Pro
     130                 135                 140

 atg gtc tca gca cct gtc aag gat caa ggt ccc ata gtc cca gca cct      480
 Met Val Ser Ala Pro Val Lys Asp Gln Gly Pro Ile Val Pro Ala Pro
 145                 150                 155                 160

 gtc aag ggt gaa ggt ccc ata gtc cca gca cct gtc aag gat gaa ggt      528
 Val Lys Gly Glu Gly Pro Ile Val Pro Ala Pro Val Lys Asp Glu Gly
                 165                 170                 175

 ccc atg gtc tca gca cct atc aag gat caa gat ccc atg gtc cca gag      576
 Pro Met Val Ser Ala Pro Ile Lys Asp Gln Asp Pro Met Val Pro Glu
             180                 185                 190

 cat ccg aag gat gaa agt gcc atg gcc aca gca ccc ata aag aat caa      624
 His Pro Lys Asp Glu Ser Ala Met Ala Thr Ala Pro Ile Lys Asn Gln
         195                 200                 205

 ggt tcc atg gtc tct gag cct gta aag aat caa ggt tta gtg gtc tca      672
 Gly Ser Met Val Ser Glu Pro Val Lys Asn Gln Gly Leu Val Val Ser
     210                 215                 220

 ggg cca gtc aag gat caa gat gtt gta gtc cca gag cat gca aag gtt      720
 Gly Pro Val Lys Asp Gln Asp Val Val Val Pro Glu His Ala Lys Val
 225                 230                 235                 240

 cac gat tct gca gtt gtg gca cct gta aag aat caa ggt cct gtg gtc      768
 His Asp Ser Ala Val Val Ala Pro Val Lys Asn Gln Gly Pro Val Val
                 245                 250                 255

 ccc gag tcc gtg aag aat caa gac ccc att ctc cca gta cta gtt aag      816
 Pro Glu Ser Val Lys Asn Gln Asp Pro Ile Leu Pro Val Leu Val Lys
             260                 265                 270

 gat caa ggc ccc aca gtc cta cag cct cca aag aat caa ggt cgt ata      864
 Asp Gln Gly Pro Thr Val Leu Gln Pro Pro Lys Asn Gln Gly Arg Ile
         275                 280                 285

 gtc cct gaa cct ctg aag aat caa gtt cct ata gtc cca gtg cct ctg      912
 Val Pro Glu Pro Leu Lys Asn Gln Val Pro Ile Val Pro Val Pro Leu
     290                 295                 300

 aag gat caa gat cct ctg gtg cca gta cca gca aag gac caa ggt cct      960
 Lys Asp Gln Asp Pro Leu Val Pro Val Pro Ala Lys Asp Gln Gly Pro
 305                 310                 315                 320

 gca gtc cct gaa cct ctg aag act caa ggt ccc agg gac cct cag cta     1008
 Ala Val Pro Glu Pro Leu Lys Thr Gln Gly Pro Arg Asp Pro Gln Leu
                 325                 330                 335

 cct act gtc tca cct cta ccc cga gtc atg atc cca act gcc ccc cat     1056
 Pro Thr Val Ser Pro Leu Pro Arg Val Met Ile Pro Thr Ala Pro His
             340                 345                 350

 acg gaa tac att gag agc tcc cct tga                                 1083
 Thr Glu Tyr Ile Glu Ser Ser Pro 
         355                 360





      <210> 73
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 73
  atg atg agg cgg ggc ctg cca ttg gca gga tgg gtg ttc ggg cgc cca      48
  Met Met Arg Arg Gly Leu Pro Leu Ala Gly Trp Val Phe Gly Arg Pro
    1               5                  10                  15

 ttt cac cct cat tgc ctt ctg ctt gca agg aat ata gca gat ccc cag       96
 Phe His Pro His Cys Leu Leu Leu Ala Arg Asn Ile Ala Asp Pro Gln
              20                  25                  30

 gat gct gct cgt cgt gag gat tta tct caa aaa cca aca tcc aaa atg      144
 Asp Ala Ala Arg Arg Glu Asp Leu Ser Gln Lys Pro Thr Ser Lys Met
          35                  40                  45

 ggc aaa gtt cga cct ctg tta agt gga ggg att tgt gag ata aaa att      192
 Gly Lys Val Arg Pro Leu Leu Ser Gly Gly Ile Cys Glu Ile Lys Ile
      50                  55                  60

 caa aat gtt ggc ctg agg cct gag agt gtc acc aaa gac aga ggg agc      240
 Gln Asn Val Gly Leu Arg Pro Glu Ser Val Thr Lys Asp Arg Gly Ser
  65                  70                  75                  80

 ttc act gag act cag agg gaa aag gaa aag agc ctc aaa cat ttt tag      288
 Phe Thr Glu Thr Gln Arg Glu Lys Glu Lys Ser Leu Lys His Phe 
                  85                  90                  95





      <210> 74
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 74
  atg cct ggt ttc agc acg acc cgc ctg cca agg gcc tgt gct ggg gtg      48
  Met Pro Gly Phe Ser Thr Thr Arg Leu Pro Arg Ala Cys Ala Gly Val
    1               5                  10                  15

 agg aga tta cct act atc aca ctc acc ttc acc ttt ccg att ctg gcc       96
 Arg Arg Leu Pro Thr Ile Thr Leu Thr Phe Thr Phe Pro Ile Leu Ala
              20                  25                  30

 tat ttg gcc aga atc cag gtt cta ctc cat gtc agc aga caa ccc aac      144
 Tyr Leu Ala Arg Ile Gln Val Leu Leu His Val Ser Arg Gln Pro Asn
          35                  40                  45

 act cta ctg agt gat ggg gat gag ggg cag aaa cat ctg ggg atc tca      192
 Thr Leu Leu Ser Asp Gly Asp Glu Gly Gln Lys His Leu Gly Ile Ser
      50                  55                  60

 ggt tct aat gct ggc tct gga aag atg ctc cag gga ggc gac tgc caa      240
 Gly Ser Asn Ala Gly Ser Gly Lys Met Leu Gln Gly Gly Asp Cys Gln
  65                  70                  75                  80

 gtc cca gaa cca ggg ctc aca ggc agt gct cag gat gaa gct gcc acg      288
 Val Pro Glu Pro Gly Leu Thr Gly Ser Ala Gln Asp Glu Ala Ala Thr
                  85                  90                  95

 ggg aac cct aat gtt aag tag                                          309
 Gly Asn Pro Asn Val Lys 
             100





      <210> 75
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 75
  atg gtg gtg ttc gtt ggc cgc cgc ctc ccg gcg ctc cta ggg ctg ttt      48
  Met Val Val Phe Val Gly Arg Arg Leu Pro Ala Leu Leu Gly Leu Phe
    1               5                  10                  15

 aag aag aag ggt gtc att gcc ctc ttc tgc cgc cag tat gac atc atc       96
 Lys Lys Lys Gly Val Ile Ala Leu Phe Cys Arg Gln Tyr Asp Ile Ile
              20                  25                  30

 aag gac aat gaa ccc aat aac aac aag gaa aaa acc aag agt gca tca      144
 Lys Asp Asn Glu Pro Asn Asn Asn Lys Glu Lys Thr Lys Ser Ala Ser
          35                  40                  45

 gaa acc agc aca cca gag cac cag ggc ggg ggg ctt ctc cgc agc aag      192
 Glu Thr Ser Thr Pro Glu His Gln Gly Gly Gly Leu Leu Arg Ser Lys
      50                  55                  60

 cct tgc aag aag gct att cac aat tag                                  219
 Pro Cys Lys Lys Ala Ile His Asn 
  65                  70





      <210> 76
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 76
  atg ggg gtg gtc cca ctg gcg tcc aag atc ctg agc tgc ctc ccc ctg      48
  Met Gly Val Val Pro Leu Ala Ser Lys Ile Leu Ser Cys Leu Pro Leu
    1               5                  10                  15

 gga cgt ggt gcc tgc aag ccc cgc act tac ctc att ggg ctc cca aag       96
 Gly Arg Gly Ala Cys Lys Pro Arg Thr Tyr Leu Ile Gly Leu Pro Lys
              20                  25                  30

 cca gac gtc aaa ggt cgg ctt ccg cag ggc ctc gat ggt ctc tgg aga      144
 Pro Asp Val Lys Gly Arg Leu Pro Gln Gly Leu Asp Gly Leu Trp Arg
          35                  40                  45

 gag cag gca cct gcg tca gac tca cag gcc aca tac ttc tgg aaa ggg      192
 Glu Gln Ala Pro Ala Ser Asp Ser Gln Ala Thr Tyr Phe Trp Lys Gly
      50                  55                  60

 cca atg cta cgg gtg gag atc cca tcg gtg gat gcc aga ggc agg cta      240
 Pro Met Leu Arg Val Glu Ile Pro Ser Val Asp Ala Arg Gly Arg Leu
  65                  70                  75                  80

 gag gac atg ggg tcc gga agt gca tgt ggc tgg agc cag tgt ggt cgc      288
 Glu Asp Met Gly Ser Gly Ser Ala Cys Gly Trp Ser Gln Cys Gly Arg
                  85                  90                  95

 tgt cgt gat ggc cga gtc cag atg agc tgc cgc tgg gga aac aca ggg      336
 Cys Arg Asp Gly Arg Val Gln Met Ser Cys Arg Trp Gly Asn Thr Gly
             100                 105                 110

 tac ctg agg tct gag gtc ggg acg tct ttg tcc aac cac taa              378
 Tyr Leu Arg Ser Glu Val Gly Thr Ser Leu Ser Asn His 
         115                 120                 125





      <210> 77
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 77
  atg aag ctc tgc gtg act gtc ctg tct ctc ctc gtg cta gta gct gcc      48
  Met Lys Leu Cys Val Thr Val Leu Ser Leu Leu Val Leu Val Ala Ala
    1               5                  10                  15

 ttc tgc tct cta gca ctc tca gca cca att aaa tta ggg gct tat gga       96
 Phe Cys Ser Leu Ala Leu Ser Ala Pro Ile Lys Leu Gly Ala Tyr Gly
              20                  25                  30

 ggt cag gta att aat gga gtt tta gct cag gtc caa ctt aca gtg ggc      144
 Gly Gln Val Ile Asn Gly Val Leu Ala Gln Val Gln Leu Thr Val Gly
          35                  40                  45

 cca gtg ggt ccc tgg att cat cct gtg gtc att tcc cca atg aca gaa      192
 Pro Val Gly Pro Trp Ile His Pro Val Val Ile Ser Pro Met Thr Glu
      50                  55                  60

 tgt gta att ggc ata gat ata ttc aac agc tgg cag aac ccc tac att      240
 Cys Val Ile Gly Ile Asp Ile Phe Asn Ser Trp Gln Asn Pro Tyr Ile
  65                  70                  75                  80

 ggc tcc ctg act ggt att gac tta gca aat gcc ttt ttc tcc att cct      288
 Gly Ser Leu Thr Gly Ile Asp Leu Ala Asn Ala Phe Phe Ser Ile Pro
                  85                  90                  95

 gtc cat aag gcc cac cag aag caa ttt gcc ttc agc tgg caa ggt cag      336
 Val His Lys Ala His Gln Lys Gln Phe Ala Phe Ser Trp Gln Gly Gln
             100                 105                 110

 caa tat acc ttt act gtc cta cct cac ggg tat atc aac tct cca gct      384
 Gln Tyr Thr Phe Thr Val Leu Pro His Gly Tyr Ile Asn Ser Pro Ala
         115                 120                 125

 ttg cgt cat aat ctt att cag aga gac ctt gat cac ttt ttg ctt ctg      432
 Leu Arg His Asn Leu Ile Gln Arg Asp Leu Asp His Phe Leu Leu Leu
     130                 135                 140

 aaa gat atc aca ctg gtc cat tac aat gac att atg atg att gga tcc      480
 Lys Asp Ile Thr Leu Val His Tyr Asn Asp Ile Met Met Ile Gly Ser
 145                 150                 155                 160

 agt gag caa aaa gta gca aac aca ctg gac tta ttg cca ccc ctg tca      528
 Ser Glu Gln Lys Val Ala Asn Thr Leu Asp Leu Leu Pro Pro Leu Ser
                 165                 170                 175

 ccg ccc aat ggg ccc atg aac aaa gtg gcc atg gtg gca ggg atg gag      576
 Pro Pro Asn Gly Pro Met Asn Lys Val Ala Met Val Ala Gly Met Glu
             180                 185                 190

 gct aca cat ggg ttc agc aag ata gac ttc cac tca cca aga ctg acc      624
 Ala Thr His Gly Phe Ser Lys Ile Asp Phe His Ser Pro Arg Leu Thr
         195                 200                 205

 tgg cta tgg cca ctg ctg agt gtc caa ttt gcc aac aga aga gac caa      672
 Trp Leu Trp Pro Leu Leu Ser Val Gln Phe Ala Asn Arg Arg Asp Gln
     210                 215                 220

 tat tga                                                              678
 Tyr 
 225





      <210> 78
      <211> 651
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(651)

      <400> 78
  atg gac atc atg acc aag agc gag gac tca ggc cag act gcc tgg ctg      48
  Met Asp Ile Met Thr Lys Ser Glu Asp Ser Gly Gln Thr Ala Trp Leu
    1               5                  10                  15

 caa atc aca gct ctg cta cct atg acc tgg gtg acc tgg aca ttc ttg       96
 Gln Ile Thr Ala Leu Leu Pro Met Thr Trp Val Thr Trp Thr Phe Leu
              20                  25                  30

 gag tct aat gtc tgt atc cct cgg aac caa ggt gga cct gag gca ttg      144
 Glu Ser Asn Val Cys Ile Pro Arg Asn Gln Gly Gly Pro Glu Ala Leu
          35                  40                  45

 gcc act ggc ctg aga gta tta gtc act ttc atg aat gtg gac tgg gaa      192
 Ala Thr Gly Leu Arg Val Leu Val Thr Phe Met Asn Val Asp Trp Glu
      50                  55                  60

 aca gag caa gac tct gtc aag aaa gaa aaa gaa aga aag aaa aag aaa      240
 Thr Glu Gln Asp Ser Val Lys Lys Glu Lys Glu Arg Lys Lys Lys Lys
  65                  70                  75                  80

 gaa agg aag aaa aag aaa gaa agg aag aaa gga aga aag gaa gga agg      288
 Glu Arg Lys Lys Lys Lys Glu Arg Lys Lys Gly Arg Lys Glu Gly Arg
                  85                  90                  95

 aag gag agg gag aag aag aag aag aag gag aag gag aag aag aag aag      336
 Lys Glu Arg Glu Lys Lys Lys Lys Lys Glu Lys Glu Lys Lys Lys Lys
             100                 105                 110

 aag aag aag gag aag gag aag aaa aag aag aag aag aag aag aag aga      384
 Lys Lys Lys Glu Lys Glu Lys Lys Lys Lys Lys Lys Lys Lys Lys Arg
         115                 120                 125

 agg aag gaa gga agg aag gaa gga agg gaa gga agg aag gaa agt agg      432
 Arg Lys Glu Gly Arg Lys Glu Gly Arg Glu Gly Arg Lys Glu Ser Arg
     130                 135                 140

 aag gaa ctt ccc gag act gca gaa ttt ata aag aat aga ggt tta att      480
 Lys Glu Leu Pro Glu Thr Ala Glu Phe Ile Lys Asn Arg Gly Leu Ile
 145                 150                 155                 160

 gac tca cag ttc agc atg gct ggg gag acc tca gga aac tta caa tca      528
 Asp Ser Gln Phe Ser Met Ala Gly Glu Thr Ser Gly Asn Leu Gln Ser
                 165                 170                 175

 tgg cgg aag agg aag caa ata cat cct tct tca tgt ggc agc aga aag      576
 Trp Arg Lys Arg Lys Gln Ile His Pro Ser Ser Cys Gly Ser Arg Lys
             180                 185                 190

 gag aag aat gag agc aga gcg aag gga gaa gcc cct tat aaa acc atc      624
 Glu Lys Asn Glu Ser Arg Ala Lys Gly Glu Ala Pro Tyr Lys Thr Ile
         195                 200                 205

 aga tct tgt gag aac tca cta tca tga                                  651
 Arg Ser Cys Glu Asn Ser Leu Ser 
     210                 215





      <210> 79
      <211> 471
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(471)

      <400> 79
  atg gct tcc cgc cgt ggc ctg cgt tgg tgc tgc ctt gcg ctc cct ggc      48
  Met Ala Ser Arg Arg Gly Leu Arg Trp Cys Cys Leu Ala Leu Pro Gly
    1               5                  10                  15

 cgc cga gtg tcc cgg ctt cgt tcg ccc cgg ccc ccg gct ctc ttt ccg       96
 Arg Arg Val Ser Arg Leu Arg Ser Pro Arg Pro Pro Ala Leu Phe Pro
              20                  25                  30

 cct cgt tgt tgt cct ttt tgc gtg tgc gtc ctc gcc tct tcc ctt cgt      144
 Pro Arg Cys Cys Pro Phe Cys Val Cys Val Leu Ala Ser Ser Leu Arg
          35                  40                  45

 gct gtt tgt gcg ggt ggg cgg ctc ctg gtg cgc ggt gcg gcc gcc tgc      192
 Ala Val Cys Ala Gly Gly Arg Leu Leu Val Arg Gly Ala Ala Ala Cys
      50                  55                  60

 tgc tcg gtc cgg ggc gcg ctg cgg tcg gtg ctc ccg ggt gcc gcg tgt      240
 Cys Ser Val Arg Gly Ala Leu Arg Ser Val Leu Pro Gly Ala Ala Cys
  65                  70                  75                  80

 gcg tgt gcc aat cta agg aat gct ggc ctt gca ttg agc aac tgt gtg      288
 Ala Cys Ala Asn Leu Arg Asn Ala Gly Leu Ala Leu Ser Asn Cys Val
                  85                  90                  95

 aat ggg ttt gaa gac cag gaa cct gga cca gga gac gga aca cgt gtt      336
 Asn Gly Phe Glu Asp Gln Glu Pro Gly Pro Gly Asp Gly Thr Arg Val
             100                 105                 110

 cta ctt tgg agt aga gtc cag cga acc cgg tcg acc ccg gca cgg gac      384
 Leu Leu Trp Ser Arg Val Gln Arg Thr Arg Ser Thr Pro Ala Arg Asp
         115                 120                 125

 agg agc aca aga cgc cgt aaa gga aag ggg ggg gag ccc aac cac ccc      432
 Arg Ser Thr Arg Arg Arg Lys Gly Lys Gly Gly Glu Pro Asn His Pro
     130                 135                 140

 agg aaa gat gta cag cag aaa aac gtg cag acc acg tag                  471
 Arg Lys Asp Val Gln Gln Lys Asn Val Gln Thr Thr 
 145                 150                 155





      <210> 80
      <211> 597
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(597)

      <400> 80
  atg att ggg ttc ttg gtg gtg ccc tct ttc tgc ttg atg gat agc tgt      48
  Met Ile Gly Phe Leu Val Val Pro Ser Phe Cys Leu Met Asp Ser Cys
    1               5                  10                  15

 ctt ctt gct gta tca tca cat ggc aga gag cag aaa gac caa gcg agc       96
 Leu Leu Ala Val Ser Ser His Gly Arg Glu Gln Lys Asp Gln Ala Ser
              20                  25                  30

 cct ctg ttg cct ctt tta gaa ggg cac cga ccc cat cat gag gct ctg      144
 Pro Leu Leu Pro Leu Leu Glu Gly His Arg Pro His His Glu Ala Leu
          35                  40                  45

 cac cct gat cag tgc cca aag gcc cca cct ttt aat aac atc cca ttg      192
 His Pro Asp Gln Cys Pro Lys Ala Pro Pro Phe Asn Asn Ile Pro Leu
      50                  55                  60

 gag aca tca gtt aaa gga gaa aat gtt tat ttc aag gtt tat ttt cag      240
 Glu Thr Ser Val Lys Gly Glu Asn Val Tyr Phe Lys Val Tyr Phe Gln
  65                  70                  75                  80

 ctg tta aaa att gcc aaa aag cct ttc agc tgg aac cac cat ctt cca      288
 Leu Leu Lys Ile Ala Lys Lys Pro Phe Ser Trp Asn His His Leu Pro
                  85                  90                  95

 gta att cgc caa aat gac aaa cac aaa ggg aaa gag gag agg tac ctg      336
 Val Ile Arg Gln Asn Asp Lys His Lys Gly Lys Glu Glu Arg Tyr Leu
             100                 105                 110

 gta tgt tct cca agc ctt ttg gaa aac atg gag ttg ttc gtt tgg cca      384
 Val Cys Ser Pro Ser Leu Leu Glu Asn Met Glu Leu Phe Val Trp Pro
         115                 120                 125

 ggt gtt acc atg gca aaa ctg gaa gcg ttt aca atg ttc ccc agt gta      432
 Gly Val Thr Met Ala Lys Leu Glu Ala Phe Thr Met Phe Pro Ser Val
     130                 135                 140

 ctg ctg gca ttg ttg caa atg aac aag ggc atg att ctt gac aag aga      480
 Leu Leu Ala Leu Leu Gln Met Asn Lys Gly Met Ile Leu Asp Lys Arg
 145                 150                 155                 160

 att aat gtg ggt att gag cac att aag cac tct ggg agt caa gat agc      528
 Ile Asn Val Gly Ile Glu His Ile Lys His Ser Gly Ser Gln Asp Ser
                 165                 170                 175

 ttc ctg aaa cac gtg aag gaa aat gat cag aaa aag aag ccc aag aga      576
 Phe Leu Lys His Val Lys Glu Asn Asp Gln Lys Lys Lys Pro Lys Arg
             180                 185                 190

 agg gta cct ggg ctc aac tga                                          597
 Arg Val Pro Gly Leu Asn 
         195





      <210> 81
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 81
  atg cgg ccc ctg ctg cta ctg gcc ctg ctg ggc tgg ctg ctg ctg gcc      48
  Met Arg Pro Leu Leu Leu Leu Ala Leu Leu Gly Trp Leu Leu Leu Ala
    1               5                  10                  15

 gaa gcg aag ggc gac gcc aag ccg gag gcc ctc cct ggc atg ggc cat       96
 Glu Ala Lys Gly Asp Ala Lys Pro Glu Ala Leu Pro Gly Met Gly His
              20                  25                  30

 ctc cag ggc tgt ccc gag aag ggc ata gac tgc gga cag tcc cag caa      144
 Leu Gln Gly Cys Pro Glu Lys Gly Ile Asp Cys Gly Gln Ser Gln Gln
          35                  40                  45

 agc caa gca gaa gtg gcg gta ctt tcc atg gca ttc tcc tcc ttc agc      192
 Ser Gln Ala Glu Val Ala Val Leu Ser Met Ala Phe Ser Ser Phe Ser
      50                  55                  60

 tta ccc tcc tgg aga acc tga                                          213
 Leu Pro Ser Trp Arg Thr 
  65                  70





      <210> 82
      <211> 282
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(282)

      <400> 82
  atg tgg gct ggc gtc tgc gcg tac cgt gtg gtg gag acg ttg agt gtg      48
  Met Trp Ala Gly Val Cys Ala Tyr Arg Val Val Glu Thr Leu Ser Val
    1               5                  10                  15

 gct ccc gct ctc acc aac tgc act aag cac tcc aac ttc gaa aac aag       96
 Ala Pro Ala Leu Thr Asn Cys Thr Lys His Ser Asn Phe Glu Asn Lys
              20                  25                  30

 agg ggt aat gaa aac acg cag aca tgt cag tac act att caa tat tac      144
 Arg Gly Asn Glu Asn Thr Gln Thr Cys Gln Tyr Thr Ile Gln Tyr Tyr
          35                  40                  45

 atg aat aat cga aat tct ata atg aaa agt gac ttt tcc act tta aaa      192
 Met Asn Asn Arg Asn Ser Ile Met Lys Ser Asp Phe Ser Thr Leu Lys
      50                  55                  60

 gaa tca gaa act gct ttc caa aag aca cag ctg ctt tgt gaa tgt agc      240
 Glu Ser Glu Thr Ala Phe Gln Lys Thr Gln Leu Leu Cys Glu Cys Ser
  65                  70                  75                  80

 acc agg ggc agc aag gta aac cgc aac ttc atc agc tgg taa              282
 Thr Arg Gly Ser Lys Val Asn Arg Asn Phe Ile Ser Trp 
                  85                  90





      <210> 83
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 83
  atg ttg gcc aga ggc aaa gaa tct gca ttt cca tac cgt ctc att gtc      48
  Met Leu Ala Arg Gly Lys Glu Ser Ala Phe Pro Tyr Arg Leu Ile Val
    1               5                  10                  15

 ttc ttc atc ttt ctc atc ctc cac aaa tcg gat cgc act gac tct gtt       96
 Phe Phe Ile Phe Leu Ile Leu His Lys Ser Asp Arg Thr Asp Ser Val
              20                  25                  30

 gac agc acg ctc gtt cca ggc ttc atc aga gac atc att tac caa gtt      144
 Asp Ser Thr Leu Val Pro Gly Phe Ile Arg Asp Ile Ile Tyr Gln Val
          35                  40                  45

 ctc cag tgc acc aca gcg agg cag att ctc tgc agt ttc aat gta aag      192
 Leu Gln Cys Thr Thr Ala Arg Gln Ile Leu Cys Ser Phe Asn Val Lys
      50                  55                  60

 aga gaa agt caa ggt gat ttt gga agg acc cag aag gag gag ttc ttt      240
 Arg Glu Ser Gln Gly Asp Phe Gly Arg Thr Gln Lys Glu Glu Phe Phe
  65                  70                  75                  80

 acc tct gat ggc cac agc ctc act gac agg gct ggt gtg aag ctg cag      288
 Thr Ser Asp Gly His Ser Leu Thr Asp Arg Ala Gly Val Lys Leu Gln
                  85                  90                  95

 gat tac ctg ttt cca gga gca cct gat gaa tca ggc caa gag gaa gga      336
 Asp Tyr Leu Phe Pro Gly Ala Pro Asp Glu Ser Gly Gln Glu Glu Gly
             100                 105                 110

 ggt gga gga gct tcg gtg tca ggc tgg ggt tca gag gta cgg ctg cat      384
 Gly Gly Gly Ala Ser Val Ser Gly Trp Gly Ser Glu Val Arg Leu His
         115                 120                 125

 gcc ctg aag gag agc ttc caa gtc agc agt tgg ctg agg ctg aag acc      432
 Ala Leu Lys Glu Ser Phe Gln Val Ser Ser Trp Leu Arg Leu Lys Thr
     130                 135                 140

 ccc gct agc gtc ctg atc tag                                          453
 Pro Ala Ser Val Leu Ile 
 145                 150





      <210> 84
      <211> 450
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(450)

      <400> 84
  atg gca gct gct gcc gtg att ctt agg atc ctg tta ctt ctt tta ctt      48
  Met Ala Ala Ala Ala Val Ile Leu Arg Ile Leu Leu Leu Leu Leu Leu
    1               5                  10                  15

 ctt ttt cag tac agc cta cgc cct cag aca aag atg cct gtg cag tca       96
 Leu Phe Gln Tyr Ser Leu Arg Pro Gln Thr Lys Met Pro Val Gln Ser
              20                  25                  30

 gat cct ctc cct tac gct gct ccc tgc ggg atc tgt acc ccc gat ttg      144
 Asp Pro Leu Pro Tyr Ala Ala Pro Cys Gly Ile Cys Thr Pro Asp Leu
          35                  40                  45

 gtg gta ttc ctg gct tgt gct aat cag aga ctc aaa gaa aga tta ctg      192
 Val Val Phe Leu Ala Cys Ala Asn Gln Arg Leu Lys Glu Arg Leu Leu
      50                  55                  60

 aag cgt gca gaa cag cag ggc cga cca gac gac aat gta aaa gct acc      240
 Lys Arg Ala Glu Gln Gln Gly Arg Pro Asp Asp Asn Val Lys Ala Thr
  65                  70                  75                  80

 caa agg aga cta atg aac ttc aag cag aat gct gct cca ttg gtt aaa      288
 Gln Arg Arg Leu Met Asn Phe Lys Gln Asn Ala Ala Pro Leu Val Lys
                  85                  90                  95

 tac ttc cag gaa aag ggg ctc atc atg aca cta tct gtt gac atg cct      336
 Tyr Phe Gln Glu Lys Gly Leu Ile Met Thr Leu Ser Val Asp Met Pro
             100                 105                 110

 gat cat gac att ttc cca tat cca ggg tac cac agc agg cac tgc aag      384
 Asp His Asp Ile Phe Pro Tyr Pro Gly Tyr His Ser Arg His Cys Lys
         115                 120                 125

 gaa tac aaa gat gat gtg gag cca gat cct gtc ttc agg gag ttt gtg      432
 Glu Tyr Lys Asp Asp Val Glu Pro Asp Pro Val Phe Arg Glu Phe Val
     130                 135                 140

 acg cag gca cag aga tga                                              450
 Thr Gln Ala Gln Arg 
 145





      <210> 85
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 85
  atg ctg ctg ttt gtc cac ctg tgg ctg tgc cac cag ggc gac ctg aca      48
  Met Leu Leu Phe Val His Leu Trp Leu Cys His Gln Gly Asp Leu Thr
    1               5                  10                  15

 tcc gct ctg gac tcg gtg gag ctg gac att tta tgc aac gag gag atc       96
 Ser Ala Leu Asp Ser Val Glu Leu Asp Ile Leu Cys Asn Glu Glu Ile
              20                  25                  30

 ctg ggc aag gac cac aca ctc aag ttc gtg gtt gtc act agg tgg aga      144
 Leu Gly Lys Asp His Thr Leu Lys Phe Val Val Val Thr Arg Trp Arg
          35                  40                  45

 ttc aag ggt gcg ggc aat ggc cac gtg gcc aag gcc ctg cag gaa cgc      192
 Phe Lys Gly Ala Gly Asn Gly His Val Ala Lys Ala Leu Gln Glu Arg
      50                  55                  60

 gcc gag gtc tcc ctc acc ctc cag gtg tcc ttc gca ccc aac agt gcg      240
 Ala Glu Val Ser Leu Thr Leu Gln Val Ser Phe Ala Pro Asn Ser Ala
  65                  70                  75                  80

 tct gag gaa cga gct gca gtt tga                                      264
 Ser Glu Glu Arg Ala Ala Val 
                  85





      <210> 86
      <211> 225
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(225)

      <400> 86
  atg tcg ctc aaa atg ctg ata gcg ctg agg gag cgg ctt ctg ctc tcc      48
  Met Ser Leu Lys Met Leu Ile Ala Leu Arg Glu Arg Leu Leu Leu Ser
    1               5                  10                  15

 ctg ctg ccg gcc cac atc gcc atg gag atg aaa gcg gag atc atc cag       96
 Leu Leu Pro Ala His Ile Ala Met Glu Met Lys Ala Glu Ile Ile Gln
              20                  25                  30

 agg ctg cag ggc ccc aag gcg ggc cag atg gag aac aca aat aac ttc      144
 Arg Leu Gln Gly Pro Lys Ala Gly Gln Met Glu Asn Thr Asn Asn Phe
          35                  40                  45

 cac aac ctg tat gtg aag cgg cat aca aac gtg agg tac gac gct atg      192
 His Asn Leu Tyr Val Lys Arg His Thr Asn Val Arg Tyr Asp Ala Met
      50                  55                  60

 ctt gct cct tgg ctg gtc tgg gag tct gcc tga                          225
 Leu Ala Pro Trp Leu Val Trp Glu Ser Ala 
  65                  70





      <210> 87
      <211> 729
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(729)

      <400> 87
  atg ccg gcc tcg tcc acc gtc cac gtg ctg cag ctg ctg cgg gag ctg      48
  Met Pro Ala Ser Ser Thr Val His Val Leu Gln Leu Leu Arg Glu Leu
    1               5                  10                  15

 ctc gcc ttc gtg ctc ctc agc tac acg gtg ctc agt cgg ggc gct gct       96
 Leu Ala Phe Val Leu Leu Ser Tyr Thr Val Leu Ser Arg Gly Ala Ala
              20                  25                  30

 gct ggc cgg ctg gac cac tta ctt cct gga aat tcc ctt caa gcc ctg      144
 Ala Gly Arg Leu Asp His Leu Leu Pro Gly Asn Ser Leu Gln Ala Leu
          35                  40                  45

 gcc cga act gag tcc ccg ccc acc cgc cag cgt cac ggc gcc cga ctc      192
 Ala Arg Thr Glu Ser Pro Pro Thr Arg Gln Arg His Gly Ala Arg Leu
      50                  55                  60

 agc tcc gcg ccg gac cca cct ccg cgc cct cag gcc ctg cat atg ccc      240
 Ser Ser Ala Pro Asp Pro Pro Pro Arg Pro Gln Ala Leu His Met Pro
  65                  70                  75                  80

 cgc ccc gcg cgg aag ttc cgg cgg ttg gtt gcc ttg cgc ggc cgt tac      288
 Arg Pro Ala Arg Lys Phe Arg Arg Leu Val Ala Leu Arg Gly Arg Tyr
                  85                  90                  95

 agc ctt tgc cct aag cct cgc ccc ctt tcc ccc tgc ctg ccc aat ccc      336
 Ser Leu Cys Pro Lys Pro Arg Pro Leu Ser Pro Cys Leu Pro Asn Pro
             100                 105                 110

 gac tgc ttc ctt ggg tgg ggg cgt ggc tat ggg gcg agg cgc tct cag      384
 Asp Cys Phe Leu Gly Trp Gly Arg Gly Tyr Gly Ala Arg Arg Ser Gln
         115                 120                 125

 gtg gag gcc gtg ccc cgc tcc gcg ctc acg aag ctg cgt cac ttc cgg      432
 Val Glu Ala Val Pro Arg Ser Ala Leu Thr Lys Leu Arg His Phe Arg
     130                 135                 140

 cgt gtg cgt ctg gcg tcc gcg cgc tgc aca atg gcg gct ctg aag agt      480
 Arg Val Arg Leu Ala Ser Ala Arg Cys Thr Met Ala Ala Leu Lys Ser
 145                 150                 155                 160

 tgg ctg tcg cgc agc gta act tca ttc ttc agg tac cgc tgc ggc cgc      528
 Trp Leu Ser Arg Ser Val Thr Ser Phe Phe Arg Tyr Arg Cys Gly Arg
                 165                 170                 175

 gta gag ggg aca gga cca gag gga ggg acc gac gcg gac agc gct gtg      576
 Val Glu Gly Thr Gly Pro Glu Gly Gly Thr Asp Ala Asp Ser Ala Val
             180                 185                 190

 gcc cgg ccc acg gcg ccc gcc ttc ctt acg cgc tca tct ctc gtc cgc      624
 Ala Arg Pro Thr Ala Pro Ala Phe Leu Thr Arg Ser Ser Leu Val Arg
         195                 200                 205

 cca gct ggg tcg cgg cgt ctc gct ccg gtc ggg agg act gag gac agc      672
 Pro Ala Gly Ser Arg Arg Leu Ala Pro Val Gly Arg Thr Glu Asp Ser
     210                 215                 220

 ccc gcc tcc gcc ccc tgg gtc aag ccc ggc ttc ctt ttc agt tcg tcc      720
 Pro Ala Ser Ala Pro Trp Val Lys Pro Gly Phe Leu Phe Ser Ser Ser
 225                 230                 235                 240

 atc ttc tag                                                          729
 Ile Phe 






      <210> 88
      <211> 540
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(540)

      <400> 88
  atg aag ctg act gtg atg caa att cct cag tgc ttt tca ttc tcc tta      48
  Met Lys Leu Thr Val Met Gln Ile Pro Gln Cys Phe Ser Phe Ser Leu
    1               5                  10                  15

 gta atg tgg caa aac tgg tat tca gtt gaa act acc caa ggg aat gga       96
 Val Met Trp Gln Asn Trp Tyr Ser Val Glu Thr Thr Gln Gly Asn Gly
              20                  25                  30

 acc gag ttt cct ctt ggc aag gga gaa tgc gca gag gaa aca agt atc      144
 Thr Glu Phe Pro Leu Gly Lys Gly Glu Cys Ala Glu Glu Thr Ser Ile
          35                  40                  45

 tca atg gga tcg ccg acc aca gag agt gac tta aga gag aaa aca cct      192
 Ser Met Gly Ser Pro Thr Thr Glu Ser Asp Leu Arg Glu Lys Thr Pro
      50                  55                  60

 gaa gac aat tct agg gtg ttc caa tac cag ggg tat ggg att gta tcg      240
 Glu Asp Asn Ser Arg Val Phe Gln Tyr Gln Gly Tyr Gly Ile Val Ser
  65                  70                  75                  80

 att gta aca gat ttt gca ctc cag ctc atc aga ggc ctg aga ctc cgc      288
 Ile Val Thr Asp Phe Ala Leu Gln Leu Ile Arg Gly Leu Arg Leu Arg
                  85                  90                  95

 agt gtc ttc agg agg ttg act ggc cat ctt gaa tta tgt gtg caa tct      336
 Ser Val Phe Arg Arg Leu Thr Gly His Leu Glu Leu Cys Val Gln Ser
             100                 105                 110

 tat gcc agg aag aat gag gca tat aac acc cga tat aag cat tat gaa      384
 Tyr Ala Arg Lys Asn Glu Ala Tyr Asn Thr Arg Tyr Lys His Tyr Glu
         115                 120                 125

 caa gtc aag tct aag tcc caa gaa aga gaa gta aac aca gat aaa aca      432
 Gln Val Lys Ser Lys Ser Gln Glu Arg Glu Val Asn Thr Asp Lys Thr
     130                 135                 140

 tgc ata gct atg tct cta gac atg aag aaa tca ctt gtg cat ggc tat      480
 Cys Ile Ala Met Ser Leu Asp Met Lys Lys Ser Leu Val His Gly Tyr
 145                 150                 155                 160

 gaa gaa ata ctc aac att cac tta ctc atc tac ttt att tca tgc aaa      528
 Glu Glu Ile Leu Asn Ile His Leu Leu Ile Tyr Phe Ile Ser Cys Lys
                 165                 170                 175

 ctc ttt ctt tag                                                      540
 Leu Phe Leu 






      <210> 89
      <211> 366
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(366)

      <400> 89
  atg tgg tcc ctc aag ctg gtt cac ttt att tgg gtg gca cac aca agc      48
  Met Trp Ser Leu Lys Leu Val His Phe Ile Trp Val Ala His Thr Ser
    1               5                  10                  15

 ttt tgc aat cag ctt cca aca atc tgg tgc cgt gta ggg act gac acg       96
 Phe Cys Asn Gln Leu Pro Thr Ile Trp Cys Arg Val Gly Thr Asp Thr
              20                  25                  30

 gca ggc tct ttt cta cat gct gcc ttc ttt ctt ctg gct ttc tcc att      144
 Ala Gly Ser Phe Leu His Ala Ala Phe Phe Leu Leu Ala Phe Ser Ile
          35                  40                  45

 gag ggt gca ggc atg atg tca gac cag tcc gca cgt cca tcc ttg cag      192
 Glu Gly Ala Gly Met Met Ser Asp Gln Ser Ala Arg Pro Ser Leu Gln
      50                  55                  60

 ccc tat aac cag aca att agg agc aaa ggc tct tcc ctg ctg cca gtt      240
 Pro Tyr Asn Gln Thr Ile Arg Ser Lys Gly Ser Ser Leu Leu Pro Val
  65                  70                  75                  80

 cga agc aga tgg gtg tgg cag ctt gaa gtc aca tgt gaa gtt gat ggt      288
 Arg Ser Arg Trp Val Trp Gln Leu Glu Val Thr Cys Glu Val Asp Gly
                  85                  90                  95

 acc aca gga tgg agg gag cac agg ttc ctg aat ctc ttc ttg gag aag      336
 Thr Thr Gly Trp Arg Glu His Arg Phe Leu Asn Leu Phe Leu Glu Lys
             100                 105                 110

 gcc cat ctg ctc acc agg aat ccc att tga                              366
 Ala His Leu Leu Thr Arg Asn Pro Ile 
         115                 120





      <210> 90
      <211> 717
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(717)

      <400> 90
  atg gct gtc cta gca gca gac cct cct cgc ttc cag tct acc aag tct      48
  Met Ala Val Leu Ala Ala Asp Pro Pro Arg Phe Gln Ser Thr Lys Ser
    1               5                  10                  15

 agg tat tct gct gtt tgg ctg ttg ctt gcc ttt tcg tta gac caa ctc       96
 Arg Tyr Ser Ala Val Trp Leu Leu Leu Ala Phe Ser Leu Asp Gln Leu
              20                  25                  30

 tcc tct acc tct agt tgt aca tct cac act att acc aag tac aat aaa      144
 Ser Ser Thr Ser Ser Cys Thr Ser His Thr Ile Thr Lys Tyr Asn Lys
          35                  40                  45

 agc atc aca tgc cac cac act act att ttg gga agc cct gca atg act      192
 Ser Ile Thr Cys His His Thr Thr Ile Leu Gly Ser Pro Ala Met Thr
      50                  55                  60

 acc agt gta cca att aac cag tcc aac cct gga tat aaa atg tta gtt      240
 Thr Ser Val Pro Ile Asn Gln Ser Asn Pro Gly Tyr Lys Met Leu Val
  65                  70                  75                  80

 cct caa aca cgt gat gca gaa tgg gaa gat gag agg aag tgg gca cgc      288
 Pro Gln Thr Arg Asp Ala Glu Trp Glu Asp Glu Arg Lys Trp Ala Arg
                  85                  90                  95

 cgg gga cct acg gcc aac ccc gcg ccc caa ctt ccc gcc aca agt tct      336
 Arg Gly Pro Thr Ala Asn Pro Ala Pro Gln Leu Pro Ala Thr Ser Ser
             100                 105                 110

 ctc tgc acc ggc aaa aag aga aac tcc acc cac ttt tcc gct aac acg      384
 Leu Cys Thr Gly Lys Lys Arg Asn Ser Thr His Phe Ser Ala Asn Thr
         115                 120                 125

 tcg gac ccg ctt ttg gca aac gac ctg cct aac ttc tct cca gct gcg      432
 Ser Asp Pro Leu Leu Ala Asn Asp Leu Pro Asn Phe Ser Pro Ala Ala
     130                 135                 140

 tcg gcc tcg cag tgc agc ggc ccg cgg agc ctc aca cag gcc gca gcc      480
 Ser Ala Ser Gln Cys Ser Gly Pro Arg Ser Leu Thr Gln Ala Ala Ala
 145                 150                 155                 160

 ggt tcc ttt cag cgg cct gtc cac gcc ccg gag acg ccc agg gga agg      528
 Gly Ser Phe Gln Arg Pro Val His Ala Pro Glu Thr Pro Arg Gly Arg
                 165                 170                 175

 aga ggg cgc ggc tac atg ggg aat ggg agc tgt gtt act acc tcc acc      576
 Arg Gly Arg Gly Tyr Met Gly Asn Gly Ser Cys Val Thr Thr Ser Thr
             180                 185                 190

 ctg gcc cgc cag cgt ctg gac gaa gaa ccg ccg cca gac cag ttt gtt      624
 Leu Ala Arg Gln Arg Leu Asp Glu Glu Pro Pro Pro Asp Gln Phe Val
         195                 200                 205

 aac atc cct gca gta acc aaa aac atg agc tgg ata agg agg aga aga      672
 Asn Ile Pro Ala Val Thr Lys Asn Met Ser Trp Ile Arg Arg Arg Arg
     210                 215                 220

 gga gct ggc cga atg att ttt aag cag aag ctg aat gtt caa taa          717
 Gly Ala Gly Arg Met Ile Phe Lys Gln Lys Leu Asn Val Gln 
 225                 230                 235





      <210> 91
      <211> 525
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(525)

      <400> 91
  atg gca gaa ctt gct gtg tta act ctc ttc cta tcg gtc ctc tgt ttc      48
  Met Ala Glu Leu Ala Val Leu Thr Leu Phe Leu Ser Val Leu Cys Phe
    1               5                  10                  15

 tcc aga atg tgc atg tct caa ttt gac atc ttt tac tac agg aaa aaa       96
 Ser Arg Met Cys Met Ser Gln Phe Asp Ile Phe Tyr Tyr Arg Lys Lys
              20                  25                  30

 gct act gct tac aca aaa caa cgc cgt gat gga aaa ggt acc tac aga      144
 Ala Thr Ala Tyr Thr Lys Gln Arg Arg Asp Gly Lys Gly Thr Tyr Arg
          35                  40                  45

 gct aaa gga aaa tac aca aga atc aac aca gca ttt gaa agt aag cca      192
 Ala Lys Gly Lys Tyr Thr Arg Ile Asn Thr Ala Phe Glu Ser Lys Pro
      50                  55                  60

 gag cag tgc ttg gct gca agg ccc ata gca ccg gag agc aat cgc cgc      240
 Glu Gln Cys Leu Ala Ala Arg Pro Ile Ala Pro Glu Ser Asn Arg Arg
  65                  70                  75                  80

 agc tca gct tgg cca cca ggc aca aga aag aat ggg aag gca cca ggg      288
 Ser Ser Ala Trp Pro Pro Gly Thr Arg Lys Asn Gly Lys Ala Pro Gly
                  85                  90                  95

 tat cga tat ttc cca gct ggg aat tct gag ttt ggc tgt gag tgt gct      336
 Tyr Arg Tyr Phe Pro Ala Gly Asn Ser Glu Phe Gly Cys Glu Cys Ala
             100                 105                 110

 tgg aag gga gaa ggc agt gga agc ccc agg aac ctc tca agg ccc agc      384
 Trp Lys Gly Glu Gly Ser Gly Ser Pro Arg Asn Leu Ser Arg Pro Ser
         115                 120                 125

 ttc agc ctc acc ttc cct gtg gtc ttc ttc aag cag acc cat acc aag      432
 Phe Ser Leu Thr Phe Pro Val Val Phe Phe Lys Gln Thr His Thr Lys
     130                 135                 140

 ctc tct gtg ctt tgg aaa ctg cca gtg gcc acc aag tgc atg gga aat      480
 Leu Ser Val Leu Trp Lys Leu Pro Val Ala Thr Lys Cys Met Gly Asn
 145                 150                 155                 160

 gag cgc agc cac ctg gct cat gat gtg gcc ctg ctc acc cct taa          525
 Glu Arg Ser His Leu Ala His Asp Val Ala Leu Leu Thr Pro 
                 165                 170





      <210> 92
      <211> 135
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(135)

      <400> 92
  atg gtt ttt ttt cag tca gtc gtg aat tcc ttt tca atg ttc acc ttg      48
  Met Val Phe Phe Gln Ser Val Val Asn Ser Phe Ser Met Phe Thr Leu
    1               5                  10                  15

 aac tta ctg tct tgg agt tgt tta gaa gtg tta gat gtg aat aag gag       96
 Asn Leu Leu Ser Trp Ser Cys Leu Glu Val Leu Asp Val Asn Lys Glu
              20                  25                  30

 gaa aaa gaa tat gct gtt act gga gca tcg tat tct taa                  135
 Glu Lys Glu Tyr Ala Val Thr Gly Ala Ser Tyr Ser 
          35                  40





      <210> 93
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 93
  atg gcc tgg atg gct ctc ctg tac ccc aca ctg cca tct aca tct cta      48
  Met Ala Trp Met Ala Leu Leu Tyr Pro Thr Leu Pro Ser Thr Ser Leu
    1               5                  10                  15

 tac acg aag gta gct cct ggc acc cag ttt agt tcc tta ggg gta gca       96
 Tyr Thr Lys Val Ala Pro Gly Thr Gln Phe Ser Ser Leu Gly Val Ala
              20                  25                  30

 aca aaa gac ccc agc aag tta aag gca gga aag aca aag aaa cac acc      144
 Thr Lys Asp Pro Ser Lys Leu Lys Ala Gly Lys Thr Lys Lys His Thr
          35                  40                  45

 cta aga ggt caa tct aca aaa ctt gca aag ctg gct gct gga ctt ccc      192
 Leu Arg Gly Gln Ser Thr Lys Leu Ala Lys Leu Ala Ala Gly Leu Pro
      50                  55                  60

 agt ttt ccc tca gcc acg cag ctg ata tat gcc ctg ggg gtg gca gag      240
 Ser Phe Pro Ser Ala Thr Gln Leu Ile Tyr Ala Leu Gly Val Ala Glu
  65                  70                  75                  80

 caa tac cgt gga agg gac caa gtg ggc acc aga tca ctt gtc tat cca      288
 Gln Tyr Arg Gly Arg Asp Gln Val Gly Thr Arg Ser Leu Val Tyr Pro
                  85                  90                  95

 gaa tgc tta cct tgg act gtt aac ctc aca gat ata aaa caa tgc gtt      336
 Glu Cys Leu Pro Trp Thr Val Asn Leu Thr Asp Ile Lys Gln Cys Val
             100                 105                 110

 act gct gaa tct ttg ctg aag tag                                      360
 Thr Ala Glu Ser Leu Leu Lys 
         115





      <210> 94
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 94
  atg gta agc cgt gct tgc ttc cca ttc att ttc tgc ctt gac tgt gtc      48
  Met Val Ser Arg Ala Cys Phe Pro Phe Ile Phe Cys Leu Asp Cys Val
    1               5                  10                  15

 ttt gag ctt tat cag ttt gtg gaa aaa cag agg gac gtt aaa gac agt       96
 Phe Glu Leu Tyr Gln Phe Val Glu Lys Gln Arg Asp Val Lys Asp Ser
              20                  25                  30

 aat ttg agg ttc atc tcc cta tct cgt gat aac act cta aac cca gga      144
 Asn Leu Arg Phe Ile Ser Leu Ser Arg Asp Asn Thr Leu Asn Pro Gly
          35                  40                  45

 att ttc cac gat aat gcc aac acc tcg tgc atc aac caa aca aaa att      192
 Ile Phe His Asp Asn Ala Asn Thr Ser Cys Ile Asn Gln Thr Lys Ile
      50                  55                  60

 gaa cag gag ttc ata att aag aac aaa cag aaa aaa agc acg agc cac      240
 Glu Gln Glu Phe Ile Ile Lys Asn Lys Gln Lys Lys Ser Thr Ser His
  65                  70                  75                  80

 taa                                                                  243
 






      <210> 95
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 95
  atg aaa gtc ctg gcc ttt aac ata act tac gaa gtg cca gtg gta cta      48
  Met Lys Val Leu Ala Phe Asn Ile Thr Tyr Glu Val Pro Val Val Leu
    1               5                  10                  15

 ttg ctt gta aga gta gct gaa gtc tct gac act gtg gaa ggt tgg cta       96
 Leu Leu Val Arg Val Ala Glu Val Ser Asp Thr Val Glu Gly Trp Leu
              20                  25                  30

 ctg gtg aca gct gaa gca gta tca gag gcc tgc tca gag gta gat gga      144
 Leu Val Thr Ala Glu Ala Val Ser Glu Ala Cys Ser Glu Val Asp Gly
          35                  40                  45

 ttt gaa ttg tta atg gaa gcg cta gta gct tgt gat tcc att ctt gca      192
 Phe Glu Leu Leu Met Glu Ala Leu Val Ala Cys Asp Ser Ile Leu Ala
      50                  55                  60

 gaa gtg aac tgg gaa agc atc aga att ttc ttc ata gaa ctg tca tta      240
 Glu Val Asn Trp Glu Ser Ile Arg Ile Phe Phe Ile Glu Leu Ser Leu
  65                  70                  75                  80

 gga tgg act gag atc aca tac ttc gta tga                              270
 Gly Trp Thr Glu Ile Thr Tyr Phe Val 
                  85





      <210> 96
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 96
  atg tgg att gtc tgc ccc ttc ctc ttc gaa tgc aag ctc ccc agg ggc      48
  Met Trp Ile Val Cys Pro Phe Leu Phe Glu Cys Lys Leu Pro Arg Gly
    1               5                  10                  15

 aag act tgg ttg gtt ttt ctc act gcc aca ttc ctg gaa tgt tca agg       96
 Lys Thr Trp Leu Val Phe Leu Thr Ala Thr Phe Leu Glu Cys Ser Arg
              20                  25                  30

 cat acc aat agg aaa cag tcc cta gag atc tgc gca gac aag tca aaa      144
 His Thr Asn Arg Lys Gln Ser Leu Glu Ile Cys Ala Asp Lys Ser Lys
          35                  40                  45

 aag gag aaa tca caa cgt gac aat gag ttc ctc agt tac att tct gag      192
 Lys Glu Lys Ser Gln Arg Asp Asn Glu Phe Leu Ser Tyr Ile Ser Glu
      50                  55                  60

 cac ctg cca aat gcc agg gat aac gct ggg tgc tgt gct gtc aac gac      240
 His Leu Pro Asn Ala Arg Asp Asn Ala Gly Cys Cys Ala Val Asn Asp
  65                  70                  75                  80

 aaa gaa gat acg gtc cta ccc cta aaa agc gac gga tcg aac tgc gac      288
 Lys Glu Asp Thr Val Leu Pro Leu Lys Ser Asp Gly Ser Asn Cys Asp
                  85                  90                  95

 tgc ctt cca gca cgc atg ctt ctg gag aat aga gga gag gaa ctc gct      336
 Cys Leu Pro Ala Arg Met Leu Leu Glu Asn Arg Gly Glu Glu Leu Ala
             100                 105                 110

 tct gct tgg agg aac agg agc agg gaa cac tgg agg ctc caa gta aag      384
 Ser Ala Trp Arg Asn Arg Ser Arg Glu His Trp Arg Leu Gln Val Lys
         115                 120                 125

 aat gag tag                                                          393
 Asn Glu 
     130





      <210> 97
      <211> 135
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(135)

      <400> 97
  atg gag aca gtg ctg aca act agg aaa ctg ggc tgg ggc ctc ttg ttg      48
  Met Glu Thr Val Leu Thr Thr Arg Lys Leu Gly Trp Gly Leu Leu Leu
    1               5                  10                  15

 ttc cca ccc agc cag ctg cag cag ggg caa gca ggc aag cat gag ctc       96
 Phe Pro Pro Ser Gln Leu Gln Gln Gly Gln Ala Gly Lys His Glu Leu
              20                  25                  30

 aac cag ttc atc agc aac tgt gcc tct tcc agc aaa tga                  135
 Asn Gln Phe Ile Ser Asn Cys Ala Ser Ser Ser Lys 
          35                  40





      <210> 98
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 98
  atg agt gca atg gcc ata gtg gcc ata tgc atg gta ctt tat acc aac      48
  Met Ser Ala Met Ala Ile Val Ala Ile Cys Met Val Leu Tyr Thr Asn
    1               5                  10                  15

 aga aag gaa ggt gct tca acc ttg gta acg gat gga gaa agg tct tca       96
 Arg Lys Glu Gly Ala Ser Thr Leu Val Thr Asp Gly Glu Arg Ser Ser
              20                  25                  30

 cag ctc cta act ttc act gtg cta att cgc agt gtt ctg tct ctt ccc      144
 Gln Leu Leu Thr Phe Thr Val Leu Ile Arg Ser Val Leu Ser Leu Pro
          35                  40                  45

 atc atg agg ggc acc agt tgg aca acc ttc caa cct atc cag taa          189
 Ile Met Arg Gly Thr Ser Trp Thr Thr Phe Gln Pro Ile Gln 
      50                  55                  60





      <210> 99
      <211> 339
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(339)

      <400> 99
  atg gct cag cgg tgc gtt tgc gtg ctg gcc ctg gtg gct atg ctg ctc      48
  Met Ala Gln Arg Cys Val Cys Val Leu Ala Leu Val Ala Met Leu Leu
    1               5                  10                  15

 cta gtt ttc cct acc gtc tcc aga tcg atg ggc ccg agg agc ggg gag       96
 Leu Val Phe Pro Thr Val Ser Arg Ser Met Gly Pro Arg Ser Gly Glu
              20                  25                  30

 cat caa agg gcg tcg cga atc cct tct cag ttc agc aaa gag gaa cgc      144
 His Gln Arg Ala Ser Arg Ile Pro Ser Gln Phe Ser Lys Glu Glu Arg
          35                  40                  45

 gtc gcg atg aaa gag gcg ctg aaa ggt caa ccc gtg act ccc cgc ttc      192
 Val Ala Met Lys Glu Ala Leu Lys Gly Gln Pro Val Thr Pro Arg Phe
      50                  55                  60

 cgc cgc aaa gca tct gct act gca gct gga gcc ccg aca cgc acc cca      240
 Arg Arg Lys Ala Ser Ala Thr Ala Ala Gly Ala Pro Thr Arg Thr Pro
  65                  70                  75                  80

 gcc cgg ccc caa cac cct tcc cag cac atc gtg ccc ctg tct ggg gac      288
 Ala Arg Pro Gln His Pro Ser Gln His Ile Val Pro Leu Ser Gly Asp
                  85                  90                  95

 gcc aca ctt ccc cca tac ctg gct cct gga act ctg gtg tgc cct gcc      336
 Ala Thr Leu Pro Pro Tyr Leu Ala Pro Gly Thr Leu Val Cys Pro Ala
             100                 105                 110

 taa                                                                  339
 






      <210> 100
      <211> 915
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(915)

      <400> 100
  atg aag aag att ccc ctt tct gcc atc acc ctg acc ttc ctg tct ggg      48
  Met Lys Lys Ile Pro Leu Ser Ala Ile Thr Leu Thr Phe Leu Ser Gly
    1               5                  10                  15

 atg ctg caa gat cct gat gac aga cct ggc ttg gga gag cca gcc aga       96
 Met Leu Gln Asp Pro Asp Asp Arg Pro Gly Leu Gly Glu Pro Ala Arg
              20                  25                  30

 tct gtg aat ggg tct gat gga ggc ctg tcc tgc ctg gaa gac ctg gac      144
 Ser Val Asn Gly Ser Asp Gly Gly Leu Ser Cys Leu Glu Asp Leu Asp
          35                  40                  45

 act ggt ata ggt gag cct ggt cag gac tcc aca gcg ttc atg atc cca      192
 Thr Gly Ile Gly Glu Pro Gly Gln Asp Ser Thr Ala Phe Met Ile Pro
      50                  55                  60

 ggt cac agg gac agg gag ccc cag cag cac ttg ttc cag gat gac cca      240
 Gly His Arg Asp Arg Glu Pro Gln Gln His Leu Phe Gln Asp Asp Pro
  65                  70                  75                  80

 gca aat tgc aag gtg gca ttt ggc ctt ttc ctc agc aat tgc cag act      288
 Ala Asn Cys Lys Val Ala Phe Gly Leu Phe Leu Ser Asn Cys Gln Thr
                  85                  90                  95

 ttg tcc cag ggt gag gag gaa gcc aat gga aga gct ggg gta ctg cca      336
 Leu Ser Gln Gly Glu Glu Glu Ala Asn Gly Arg Ala Gly Val Leu Pro
             100                 105                 110

 aca aga agg ccc aat caa gat cct ccc aca aca aga gca gat tgt gag      384
 Thr Arg Arg Pro Asn Gln Asp Pro Pro Thr Thr Arg Ala Asp Cys Glu
         115                 120                 125

 cct act cga gtt gat gat gac aag ggc aaa gac ctt tat gct gag cca      432
 Pro Thr Arg Val Asp Asp Asp Lys Gly Lys Asp Leu Tyr Ala Glu Pro
     130                 135                 140

 ctt ctg cgt agt gaa cca cac agg gag ata cca gcc acc gtc ccg gag      480
 Leu Leu Arg Ser Glu Pro His Arg Glu Ile Pro Ala Thr Val Pro Glu
 145                 150                 155                 160

 cca ttc ggc ctg ggt ctg aag ccc agc aac ccg agc cca gaa tcg act      528
 Pro Phe Gly Leu Gly Leu Lys Pro Ser Asn Pro Ser Pro Glu Ser Thr
                 165                 170                 175

 tca gag tct aac ggc ccc cta ggc tgt aag ccc ctc aag gca gct gtg      576
 Ser Glu Ser Asn Gly Pro Leu Gly Cys Lys Pro Leu Lys Ala Ala Val
             180                 185                 190

 tat ggc aca gct ttt gtt ctc tgt gcc ttg tac agc acc tgc cac ctg      624
 Tyr Gly Thr Ala Phe Val Leu Cys Ala Leu Tyr Ser Thr Cys His Leu
         195                 200                 205

 cta ggg gct cgg gaa atg gcg gtg gcc aat gcc agg tcc cct cga aga      672
 Leu Gly Ala Arg Glu Met Ala Val Ala Asn Ala Arg Ser Pro Arg Arg
     210                 215                 220

 cac cca ttt ctc agt ggg cac cgt gga gca ccg gga aat gct gcc agc      720
 His Pro Phe Leu Ser Gly His Arg Gly Ala Pro Gly Asn Ala Ala Ser
 225                 230                 235                 240

 gat gca tgt gac tct gtc act cgt tta gac ttt aat cct aaa cgg ata      768
 Asp Ala Cys Asp Ser Val Thr Arg Leu Asp Phe Asn Pro Lys Arg Ile
                 245                 250                 255

 aag caa cct ttc cgt cca acg gtg aac cag cct cag aag atg gtg act      816
 Lys Gln Pro Phe Arg Pro Thr Val Asn Gln Pro Gln Lys Met Val Thr
             260                 265                 270

 ccc cag ggt att gct gct ctc aat gag gtt gac cgc atc agc ttc ctc      864
 Pro Gln Gly Ile Ala Ala Leu Asn Glu Val Asp Arg Ile Ser Phe Leu
         275                 280                 285

 tgg gag cat att cga aat gca caa tct cag gcc tca ccc cag atc tac      912
 Trp Glu His Ile Arg Asn Ala Gln Ser Gln Ala Ser Pro Gln Ile Tyr
     290                 295                 300

 tga                                                                  915
 






      <210> 101
      <211> 624
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(624)

      <400> 101
  atg atc gtg gta ctt cca tca aga atg cac tat ctc tgt atc cgc cta      48
  Met Ile Val Val Leu Pro Ser Arg Met His Tyr Leu Cys Ile Arg Leu
    1               5                  10                  15

 gct cct agc agt aat ttc ctg tcc ctc ttg gac cac atg atg cat ccg       96
 Ala Pro Ser Ser Asn Phe Leu Ser Leu Leu Asp His Met Met His Pro
              20                  25                  30

 gac tca atc ttt aac cca agg att tgc atg agt gtt gcc cag ctc ctg      144
 Asp Ser Ile Phe Asn Pro Arg Ile Cys Met Ser Val Ala Gln Leu Leu
          35                  40                  45

 ctg ggt gtg aca tac tat gat cca act aca tgg aca ctt cag gga gct      192
 Leu Gly Val Thr Tyr Tyr Asp Pro Thr Thr Trp Thr Leu Gln Gly Ala
      50                  55                  60

 tcc cag ctt cct gct gtt cct gaa act tcc ttg ttc aat tct gct ttg      240
 Ser Gln Leu Pro Ala Val Pro Glu Thr Ser Leu Phe Asn Ser Ala Leu
  65                  70                  75                  80

 gat tcc atg gga tcc tct ggc ata gca aca act gct atc cga aag aaa      288
 Asp Ser Met Gly Ser Ser Gly Ile Ala Thr Thr Ala Ile Arg Lys Lys
                  85                  90                  95

 cac aga aaa gga aaa agc aag gag gag gag gaa gac gag gag gac agg      336
 His Arg Lys Gly Lys Ser Lys Glu Glu Glu Glu Asp Glu Glu Asp Arg
             100                 105                 110

 gag gaa aaa atg cta tac agc agt gag cgc tgc agc gtg aag ctc gct      384
 Glu Glu Lys Met Leu Tyr Ser Ser Glu Arg Cys Ser Val Lys Leu Ala
         115                 120                 125

 ctg cgg gtc cga gag gcc tgc gat ctg aag act gaa aac tgg gaa gag      432
 Leu Arg Val Arg Glu Ala Cys Asp Leu Lys Thr Glu Asn Trp Glu Glu
     130                 135                 140

 acg ctc tac cct gtg ctc ctc gcc ggc ttc gat agg agc cgc agc tgc      480
 Thr Leu Tyr Pro Val Leu Leu Ala Gly Phe Asp Arg Ser Arg Ser Cys
 145                 150                 155                 160

 aaa aga gct gga gat ttc agg ctc gtt gtt aag ggt ctg cgg att cat      528
 Lys Arg Ala Gly Asp Phe Arg Leu Val Val Lys Gly Leu Arg Ile His
                 165                 170                 175

 aag gtc aga aat tcc atg aac aca gaa aaa gta ttc aaa agg tac tca      576
 Lys Val Arg Asn Ser Met Asn Thr Glu Lys Val Phe Lys Arg Tyr Ser
             180                 185                 190

 gca gct agt gaa ttc aac tgg gga cag ttg gaa ctt cag gat gtt tga      624
 Ala Ala Ser Glu Phe Asn Trp Gly Gln Leu Glu Leu Gln Asp Val 
         195                 200                 205





      <210> 102
      <211> 306
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(306)

      <400> 102
  atg atg tcc tct tta gct ttg gcc ttc tct cac tgt gtg ctg ttt gga      48
  Met Met Ser Ser Leu Ala Leu Ala Phe Ser His Cys Val Leu Phe Gly
    1               5                  10                  15

 gaa ctc tgt tat gtt gct ctg gcc ttt aac tca ggc tca gtc ttc cga       96
 Glu Leu Cys Tyr Val Ala Leu Ala Phe Asn Ser Gly Ser Val Phe Arg
              20                  25                  30

 aat gag ctg ctg ccg ctc ttc aag gag tat ggt aaa agc aag atc caa      144
 Asn Glu Leu Leu Pro Leu Phe Lys Glu Tyr Gly Lys Ser Lys Ile Gln
          35                  40                  45

 cga tgt gct gca gag gga ggc tct ctg cct att gaa aag tac cat gtc      192
 Arg Cys Ala Ala Glu Gly Gly Ser Leu Pro Ile Glu Lys Tyr His Val
      50                  55                  60

 cac cag ggg cct gct gta aat att tct gct act tcc tct ggg gga gat      240
 His Gln Gly Pro Ala Val Asn Ile Ser Ala Thr Ser Ser Gly Gly Asp
  65                  70                  75                  80

 gat ggc tta atg aca act tca atg gat tct aaa gag gaa ggc atc ctc      288
 Asp Gly Leu Met Thr Thr Ser Met Asp Ser Lys Glu Glu Gly Ile Leu
                  85                  90                  95

 tct gct ctc tgt tca tga                                              306
 Ser Ala Leu Cys Ser 
             100





      <210> 103
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 103
  atg ggg ctc gct gca aat aag ctt ttc atg ctt gaa ata ttc tac ttt      48
  Met Gly Leu Ala Ala Asn Lys Leu Phe Met Leu Glu Ile Phe Tyr Phe
    1               5                  10                  15

 gct ttc ccg ttt ccc ctt cta tct gct gcc ttt gcc ctt ccg tct gga       96
 Ala Phe Pro Phe Pro Leu Leu Ser Ala Ala Phe Ala Leu Pro Ser Gly
              20                  25                  30

 ggc agt gaa agt ggc cgg agc acc ccc agc ctc tcc gtg ctc tct gac      144
 Gly Ser Glu Ser Gly Arg Ser Thr Pro Ser Leu Ser Val Leu Ser Asp
          35                  40                  45

 agc aag ccg ccc ccc tcc acc tac cag cag gca cct cgc cac ttc cac      192
 Ser Lys Pro Pro Pro Ser Thr Tyr Gln Gln Ala Pro Arg His Phe His
      50                  55                  60

 gtc cca gat gag ggt ggc atc tgg agt cag gga ggc ttg atc tgg ggc      240
 Val Pro Asp Glu Gly Gly Ile Trp Ser Gln Gly Gly Leu Ile Trp Gly
  65                  70                  75                  80

 ctg ggt gtc tgt cgc tcg ctg ggt gcc agt tcc tgc ctg atg att cta      288
 Leu Gly Val Cys Arg Ser Leu Gly Ala Ser Ser Cys Leu Met Ile Leu
                  85                  90                  95

 aat ctg gac act ggc gta aaa gat aac atc tat agg aaa ccc cct atc      336
 Asn Leu Asp Thr Gly Val Lys Asp Asn Ile Tyr Arg Lys Pro Pro Ile
             100                 105                 110

 tac aga cag cat gga ccg atc ccc tcc acc ccg ccc ttt cca cag gct      384
 Tyr Arg Gln His Gly Pro Ile Pro Ser Thr Pro Pro Phe Pro Gln Ala
         115                 120                 125

 gac cgt ggg aac ttc atg gga tat cga ata ggg aag tgc att cta aac      432
 Asp Arg Gly Asn Phe Met Gly Tyr Arg Ile Gly Lys Cys Ile Leu Asn
     130                 135                 140

 tgt aaa gtg ctg tgc aca tga                                          453
 Cys Lys Val Leu Cys Thr 
 145                 150





      <210> 104
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 104
  atg tgc atg tat ttg ttc ttt ctg gac ttc tcg att gtg agt gtg aca      48
  Met Cys Met Tyr Leu Phe Phe Leu Asp Phe Ser Ile Val Ser Val Thr
    1               5                  10                  15

 gtg tta ttg gat ttc atg acc cgg gat cgt cgg gag tgg gct gag gag       96
 Val Leu Leu Asp Phe Met Thr Arg Asp Arg Arg Glu Trp Ala Glu Glu
              20                  25                  30

 tgg cgt gtg ggt ctc cgg aag ctc gtc gca ggc cat ctg tgt gac tcc      144
 Trp Arg Val Gly Leu Arg Lys Leu Val Ala Gly His Leu Cys Asp Ser
          35                  40                  45

 ggt gcg agt gga ggt tgg tac cgt tca gtg cga ggc tgt cac ccc gtg      192
 Gly Ala Ser Gly Gly Trp Tyr Arg Ser Val Arg Gly Cys His Pro Val
      50                  55                  60

 tgc ctg tcc acg tcc tgt gtg act ggg tgc gag gaa gtc aat ggc acc      240
 Cys Leu Ser Thr Ser Cys Val Thr Gly Cys Glu Glu Val Asn Gly Thr
  65                  70                  75                  80

 gtg gaa tgt gag gct gtg agt tga                                      264
 Val Glu Cys Glu Ala Val Ser 
                  85





      <210> 105
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 105
  atg tcc ttc cta att tgg ggg gca cag ctt gct gag ccc ttt gct ccc      48
  Met Ser Phe Leu Ile Trp Gly Ala Gln Leu Ala Glu Pro Phe Ala Pro
    1               5                  10                  15

 ctg gcg act gcc tgg aca gtc agc aag gaa ttg tct ccc agt gca ttt       96
 Leu Ala Thr Ala Trp Thr Val Ser Lys Glu Leu Ser Pro Ser Ala Phe
              20                  25                  30

 tgc cct cct ggc tgc caa ctc tgg ctg cta aag cgg ctg cca cct gct      144
 Cys Pro Pro Gly Cys Gln Leu Trp Leu Leu Lys Arg Leu Pro Pro Ala
          35                  40                  45

 gca gtc tac aca gct tcg gga aga gga aag gaa cct cag acc ttc cag      192
 Ala Val Tyr Thr Ala Ser Gly Arg Gly Lys Glu Pro Gln Thr Phe Gln
      50                  55                  60

 atc gct tcc tct cgc aac aaa cta ttt gtc gca gat ggc tct ttg ctt      240
 Ile Ala Ser Ser Arg Asn Lys Leu Phe Val Ala Asp Gly Ser Leu Leu
  65                  70                  75                  80

 tca tta gga ata aag atg gct gct gaa cca gta gaa gac aat tgc atc      288
 Ser Leu Gly Ile Lys Met Ala Ala Glu Pro Val Glu Asp Asn Cys Ile
                  85                  90                  95

 aac ttt gtg gca atg aaa ttt att gac aat acg ctt tac ttt ata gct      336
 Asn Phe Val Ala Met Lys Phe Ile Asp Asn Thr Leu Tyr Phe Ile Ala
             100                 105                 110

 gaa gat gat ggt aaa gta gaa atg aat tta ttt ttc ttt gca aac taa      384
 Glu Asp Asp Gly Lys Val Glu Met Asn Leu Phe Phe Phe Ala Asn 
         115                 120                 125





      <210> 106
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 106
  atg gcg cca gcg ctg tgg cgg gcc tgc aac gga ctc atg gcc gcc ttc      48
  Met Ala Pro Ala Leu Trp Arg Ala Cys Asn Gly Leu Met Ala Ala Phe
    1               5                  10                  15

 ttc gcg ctg gcg gcc ttg gtg cag aga tgc agt act ggc ctg gat ggt       96
 Phe Ala Leu Ala Ala Leu Val Gln Arg Cys Ser Thr Gly Leu Asp Gly
              20                  25                  30

 cca ttg ggt cca aag cca gca ggg cca tct agc atc gtg gct gct cct      144
 Pro Leu Gly Pro Lys Pro Ala Gly Pro Ser Ser Ile Val Ala Ala Pro
          35                  40                  45

 gcc cta ctt ttc aaa gaa cat ttt ctt tta tgc aat tcc acc atc tgt      192
 Ala Leu Leu Phe Lys Glu His Phe Leu Leu Cys Asn Ser Thr Ile Cys
      50                  55                  60

 cat gct aac ttc act ctt ggg ctc cac aca gtg gcc ctg cag ccc ccc      240
 His Ala Asn Phe Thr Leu Gly Leu His Thr Val Ala Leu Gln Pro Pro
  65                  70                  75                  80

 att cac atc ttc acg atg cca cgt cca gtg gaa tat gga ctg tgt ttc      288
 Ile His Ile Phe Thr Met Pro Arg Pro Val Glu Tyr Gly Leu Cys Phe
                  85                  90                  95

 ttc act cta cca aag tct cag aat gca gtt gct ggc tct gat tgc ttg      336
 Phe Thr Leu Pro Lys Ser Gln Asn Ala Val Ala Gly Ser Asp Cys Leu
             100                 105                 110

 tcc gtt tgt gct gat cca aat cac tgt ggc tga                          369
 Ser Val Cys Ala Asp Pro Asn His Cys Gly 
         115                 120





      <210> 107
      <211> 708
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(708)

      <400> 107
  atg tgg ttc ctg tat ggg aga ttt att cca gtc agt ctg gcc ttt ggc      48
  Met Trp Phe Leu Tyr Gly Arg Phe Ile Pro Val Ser Leu Ala Phe Gly
    1               5                  10                  15

 gaa ata gca tca gag tgg tgc aac cgt gct ttt gaa att cag tct gac       96
 Glu Ile Ala Ser Glu Trp Cys Asn Arg Ala Phe Glu Ile Gln Ser Asp
              20                  25                  30

 agt tca aga cac tca acc aag gcc cta ggc tgt agc atc aaa cag gac      144
 Ser Ser Arg His Ser Thr Lys Ala Leu Gly Cys Ser Ile Lys Gln Asp
          35                  40                  45

 cta gag gaa gac acg ttc aca tcc aca tgc aat ttg ttc tcc gtc ttc      192
 Leu Glu Glu Asp Thr Phe Thr Ser Thr Cys Asn Leu Phe Ser Val Phe
      50                  55                  60

 ttc tta aac gtc agt gcc agg aag cgc tta aag gat gac ttc ttc ttc      240
 Phe Leu Asn Val Ser Ala Arg Lys Arg Leu Lys Asp Asp Phe Phe Phe
  65                  70                  75                  80

 ttg tac ttg tcc ggg gag tcg ctc tcg atc agg agt gag gga gag ctc      288
 Leu Tyr Leu Ser Gly Glu Ser Leu Ser Ile Arg Ser Glu Gly Glu Leu
                  85                  90                  95

 ttt gtg atg ggc ttc ttg gtg atg cag gcc agg tcg aaa gga ggt ggg      336
 Phe Val Met Gly Phe Leu Val Met Gln Ala Arg Ser Lys Gly Gly Gly
             100                 105                 110

 atg tcg acc atg gaa gaa ggc gtg gag gtg ccg ctg gac gga agg tgg      384
 Met Ser Thr Met Glu Glu Gly Val Glu Val Pro Leu Asp Gly Arg Trp
         115                 120                 125

 ttt ctc tgg gag aaa ctc cca gag gag cca att aca cac gac aga gag      432
 Phe Leu Trp Glu Lys Leu Pro Glu Glu Pro Ile Thr His Asp Arg Glu
     130                 135                 140

 aga ttg tcc tct ttc ctc ttt atc ctg tgg tca tcc aac cct gac ccc      480
 Arg Leu Ser Ser Phe Leu Phe Ile Leu Trp Ser Ser Asn Pro Asp Pro
 145                 150                 155                 160

 tca ggc tcc tgg tac acg gac act gga atc tct cgg cct tcc acg gag      528
 Ser Gly Ser Trp Tyr Thr Asp Thr Gly Ile Ser Arg Pro Ser Thr Glu
                 165                 170                 175

 aac gac cga ggg tat aaa gta aag gcc ctg ggc ttt gct ggc aag gcc      576
 Asn Asp Arg Gly Tyr Lys Val Lys Ala Leu Gly Phe Ala Gly Lys Ala
             180                 185                 190

 ctg ctg gct tcc aag ggc ttc ccc tcc aat gac aaa agc gtc ttt ccc      624
 Leu Leu Ala Ser Lys Gly Phe Pro Ser Asn Asp Lys Ser Val Phe Pro
         195                 200                 205

 acc tcc tct gcg gca cct cca atg cca ggg gct gac gag ccc gcc tca      672
 Thr Ser Ser Ala Ala Pro Pro Met Pro Gly Ala Asp Glu Pro Ala Ser
     210                 215                 220

 ggt ccg gtt tct tca ggg acg gtt tct ggg aca tag                      708
 Gly Pro Val Ser Ser Gly Thr Val Ser Gly Thr 
 225                 230                 235





      <210> 108
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 108
  atg cac ctg ctg caa gca gcc cta ctg ttg gct gtg ccc tgc ctt ctc      48
  Met His Leu Leu Gln Ala Ala Leu Leu Leu Ala Val Pro Cys Leu Leu
    1               5                  10                  15

 tgc tat gtt gct gtt ggc tat gcc ttc tct gtg ctg ctg aca ctg ctg       96
 Cys Tyr Val Ala Val Gly Tyr Ala Phe Ser Val Leu Leu Thr Leu Leu
              20                  25                  30

 ctg act gct ccg gct ctt ttg cca gat gat ttt gag ggc ttc aat ata      144
 Leu Thr Ala Pro Ala Leu Leu Pro Asp Asp Phe Glu Gly Phe Asn Ile
          35                  40                  45

 agg gaa aaa aca ggc tgg tat gga aag aag gag ggt atg gtc aca tta      192
 Arg Glu Lys Thr Gly Trp Tyr Gly Lys Lys Glu Gly Met Val Thr Leu
      50                  55                  60

 tcg aat cca caa gtt gca aga gaa aag gag cag ttc aat gat ttg tat      240
 Ser Asn Pro Gln Val Ala Arg Glu Lys Glu Gln Phe Asn Asp Leu Tyr
  65                  70                  75                  80

 ttt aac gcc aag cag gct gag cag aag ggg tat ctg aat act gct aga      288
 Phe Asn Ala Lys Gln Ala Glu Gln Lys Gly Tyr Leu Asn Thr Ala Arg
                  85                  90                  95

 cga gaa gcc agc ctg gca ttc aaa gtg aca gag acc acc cat aac aag      336
 Arg Glu Ala Ser Leu Ala Phe Lys Val Thr Glu Thr Thr His Asn Lys
             100                 105                 110

 agt ggg ttg atc act gag agc tga                                      360
 Ser Gly Leu Ile Thr Glu Ser 
         115





      <210> 109
      <211> 795
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(795)

      <400> 109
  atg ctg tcg gtg ctc cgt aaa tgc tcc ctg ctt ccc ctt tct gct gcc      48
  Met Leu Ser Val Leu Arg Lys Cys Ser Leu Leu Pro Leu Ser Ala Ala
    1               5                  10                  15

 tgt ttg cag ctg gcc ccg ctc cct ggc cac tct ggg gag gct gaa gca       96
 Cys Leu Gln Leu Ala Pro Leu Pro Gly His Ser Gly Glu Ala Glu Ala
              20                  25                  30

 gca gtt agt gag aag gag gca aaa cca gag aag ggc gat gct gcc att      144
 Ala Val Ser Glu Lys Glu Ala Lys Pro Glu Lys Gly Asp Ala Ala Ile
          35                  40                  45

 ctc att acc cga ttc cga gcc tgg gct act gta gga gga aga gag att      192
 Leu Ile Thr Arg Phe Arg Ala Trp Ala Thr Val Gly Gly Arg Glu Ile
      50                  55                  60

 tat gta aag ggc ttt gtc cac tat aaa gtc cgg gct ctg ttt ccc tgt      240
 Tyr Val Lys Gly Phe Val His Tyr Lys Val Arg Ala Leu Phe Pro Cys
  65                  70                  75                  80

 gag aag ccg cct cgg ccc acc gag atg tcc cgg cac cat agc cgc ttc      288
 Glu Lys Pro Pro Arg Pro Thr Glu Met Ser Arg His His Ser Arg Phe
                  85                  90                  95

 gaa aga gat tac cgg gtg ggc tgg gac cgc cgc gaa tgg agc gtc aac      336
 Glu Arg Asp Tyr Arg Val Gly Trp Asp Arg Arg Glu Trp Ser Val Asn
             100                 105                 110

 ggg acg cat ggg acc acc agc atc tgc agt gtc acc tcg ggg gcc ggt      384
 Gly Thr His Gly Thr Thr Ser Ile Cys Ser Val Thr Ser Gly Ala Gly
         115                 120                 125

 ggc ggc aca gcc agc agc ctc agc gtc cgg ccc ggc ctc ctg ccg ctg      432
 Gly Gly Thr Ala Ser Ser Leu Ser Val Arg Pro Gly Leu Leu Pro Leu
     130                 135                 140

 ccc gtg gtg ccc tcc cgg ctg ccc acc ccg gct aca gct cct gct ccc      480
 Pro Val Val Pro Ser Arg Leu Pro Thr Pro Ala Thr Ala Pro Ala Pro
 145                 150                 155                 160

 tgc acc acc ggc agc agc gag gcc atc acc agc ctc gtg gcc agc tct      528
 Cys Thr Thr Gly Ser Ser Glu Ala Ile Thr Ser Leu Val Ala Ser Ser
                 165                 170                 175

 gcg tct gcg gtc acc acc aag ggc cag ccg ctg gac ctg ctg gcc aca      576
 Ala Ser Ala Val Thr Thr Lys Gly Gln Pro Leu Asp Leu Leu Ala Thr
             180                 185                 190

 tct ggc agg cgc tct gca ggg cca gct gtt ggc cat atg gag aat ggc      624
 Ser Gly Arg Arg Ser Ala Gly Pro Ala Val Gly His Met Glu Asn Gly
         195                 200                 205

 agc cgc tgg aac cga ctg ctc ggg gct cca gca gca gct ctg cag gct      672
 Ser Arg Trp Asn Arg Leu Leu Gly Ala Pro Ala Ala Ala Leu Gln Ala
     210                 215                 220

 cgg agc tgc ctg gcc ggc cgc aag ttt act gcc aag cac agt ggg cgg      720
 Arg Ser Cys Leu Ala Gly Arg Lys Phe Thr Ala Lys His Ser Gly Arg
 225                 230                 235                 240

 gtc agg ccc tta aga aag agg gtt gtg gtg gac acc aga gcc gtg gag      768
 Val Arg Pro Leu Arg Lys Arg Val Val Val Asp Thr Arg Ala Val Glu
                 245                 250                 255

 gag cgt ttt tgt ggt cca ttt ctc tag                                  795
 Glu Arg Phe Cys Gly Pro Phe Leu 
             260





      <210> 110
      <211> 648
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(648)

      <400> 110
  atg cgg agg cgc cgg gga ggg tgt ggg gtc agg gcc cgc gcg gcg ctg      48
  Met Arg Arg Arg Arg Gly Gly Cys Gly Val Arg Ala Arg Ala Ala Leu
    1               5                  10                  15

 ctt ctg ctc ccg aag act gcg gtc gga ctg gcg cag cgg agg gtg cgg       96
 Leu Leu Leu Pro Lys Thr Ala Val Gly Leu Ala Gln Arg Arg Val Arg
              20                  25                  30

 ctc ccg gag ccg agg ccg cag cgg gga gtg acc gga agt ggc ctc tgc      144
 Leu Pro Glu Pro Arg Pro Gln Arg Gly Val Thr Gly Ser Gly Leu Cys
          35                  40                  45

 agc cgc gtc cct ggg ccc atg tca ggg acg gct ctg gct gaa gca gga      192
 Ser Arg Val Pro Gly Pro Met Ser Gly Thr Ala Leu Ala Glu Ala Gly
      50                  55                  60

 gga cgg cgt ttg gag ggt ggg gtg ggc gcg tca tct cgg cgg ccc gcg      240
 Gly Arg Arg Leu Glu Gly Gly Val Gly Ala Ser Ser Arg Arg Pro Ala
  65                  70                  75                  80

 tgg act gac agc cac cac tgc ccc cac gct gcc ctc gtg ccc gcg gtt      288
 Trp Thr Asp Ser His His Cys Pro His Ala Ala Leu Val Pro Ala Val
                  85                  90                  95

 cta aga agt cga atg cca ggc gga ggc gac gtg gca aat ggc cca ggc      336
 Leu Arg Ser Arg Met Pro Gly Gly Gly Asp Val Ala Asn Gly Pro Gly
             100                 105                 110

 ttg gga ggc gct gcg gtc cag gtc ccg cag gat gtg gag gat ttt cga      384
 Leu Gly Gly Ala Ala Val Gln Val Pro Gln Asp Val Glu Asp Phe Arg
         115                 120                 125

 gga ggc gca ggg gct gga ggt gca cag gcc cat ctt gca cag gag cca      432
 Gly Gly Ala Gly Ala Gly Gly Ala Gln Ala His Leu Ala Gln Glu Pro
     130                 135                 140

 aac cac agc ctt agc tgg cgg agc aat tac agt gcc gcc gcc cct tcc      480
 Asn His Ser Leu Ser Trp Arg Ser Asn Tyr Ser Ala Ala Ala Pro Ser
 145                 150                 155                 160

 ccg ccc ggc cat gct cgc gtc cag gcg ggc tgc tgc agg ggg cct gat      528
 Pro Pro Gly His Ala Arg Val Gln Ala Gly Cys Cys Arg Gly Pro Asp
                 165                 170                 175

 ccg gtg gac gat cgg ctc ctc acc ccg gca agg ccc cca cct cgg ccg      576
 Pro Val Asp Asp Arg Leu Leu Thr Pro Ala Arg Pro Pro Pro Arg Pro
             180                 185                 190

 ctg aca gcc tcg cag gga ggc ccc agc gat gag caa ggg gct ggc ggg      624
 Leu Thr Ala Ser Gln Gly Gly Pro Ser Asp Glu Gln Gly Ala Gly Gly
         195                 200                 205

 agg acg gga ggc ccg ccg gcc tga                                      648
 Arg Thr Gly Gly Pro Pro Ala 
     210                 215





      <210> 111
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 111
  atg gcg gcg tcg gcg gct ctg tct gca gcg gcg gct gcg gcg gcc ctg      48
  Met Ala Ala Ser Ala Ala Leu Ser Ala Ala Ala Ala Ala Ala Ala Leu
    1               5                  10                  15

 tct ggc ctg gcg gtg cgg ctg tcg cgc tca gct gcg gcc cga ggc tcg       96
 Ser Gly Leu Ala Val Arg Leu Ser Arg Ser Ala Ala Ala Arg Gly Ser
              20                  25                  30

 tac ggc gcc ttc tgc aag ggg ctc acg cgc acg ctg ctc acc ttc ttc      144
 Tyr Gly Ala Phe Cys Lys Gly Leu Thr Arg Thr Leu Leu Thr Phe Phe
          35                  40                  45

 gac ctg gcc tgg cgg ctg cgc atg aac ttc ccc tac ttc tac atc gtg      192
 Asp Leu Ala Trp Arg Leu Arg Met Asn Phe Pro Tyr Phe Tyr Ile Val
      50                  55                  60

 gcc tcg gtg atg ctt aac gtc cgc ctg cag gca ttg gca ttt gta ggc      240
 Ala Ser Val Met Leu Asn Val Arg Leu Gln Ala Leu Ala Phe Val Gly
  65                  70                  75                  80

 gag aaa cca aag aca gga acc aag tct gaa aca gag ccc caa gaa gaa      288
 Glu Lys Pro Lys Thr Gly Thr Lys Ser Glu Thr Glu Pro Gln Glu Glu
                  85                  90                  95

 gct ctt ttc ctg agc tac cag tgc ccc ttg gag agg cag gga att ggg      336
 Ala Leu Phe Leu Ser Tyr Gln Cys Pro Leu Glu Arg Gln Gly Ile Gly
             100                 105                 110

 ctg gaa gaa tgg tgg aat gga ata gca aag atg gaa gat gac cct gtc      384
 Leu Glu Glu Trp Trp Asn Gly Ile Ala Lys Met Glu Asp Asp Pro Val
         115                 120                 125

 ctt tct ggg tga                                                      396
 Leu Ser Gly 
     130





      <210> 112
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 112
  atg gcg gcg cga gtg ctg cgc gcc cgc gga gcg gcc tgg gcc ggc ggc      48
  Met Ala Ala Arg Val Leu Arg Ala Arg Gly Ala Ala Trp Ala Gly Gly
    1               5                  10                  15

 ctc ctg cag cgg gcg gcc ccc tgc agc ctc ctg ccc agg ctc cgg gcc       96
 Leu Leu Gln Arg Ala Ala Pro Cys Ser Leu Leu Pro Arg Leu Arg Ala
              20                  25                  30

 ctg acc ggc gcg acc cgt ggc cag gga cag gga cag cgc gcg cct gag      144
 Leu Thr Gly Ala Thr Arg Gly Gln Gly Gln Gly Gln Arg Ala Pro Glu
          35                  40                  45

 gcc gca ggc ccc gga cgc cgt ctg ctg ggt cct cgc cgg agg ctg ttc      192
 Ala Ala Gly Pro Gly Arg Arg Leu Leu Gly Pro Arg Arg Arg Leu Phe
      50                  55                  60

 caa gcc tga                                                          201
 Gln Ala 
  65





      <210> 113
      <211> 759
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(759)

      <400> 113
  atg cgc aga agg ccc ttg gct tgc ctg gcc ctc ctg gcc cat ctc ctg      48
  Met Arg Arg Arg Pro Leu Ala Cys Leu Ala Leu Leu Ala His Leu Leu
    1               5                  10                  15

 ccg cca tgc cac tgt ggg aag ccc ctg cag cag gag ctg cac agc ctc       96
 Pro Pro Cys His Cys Gly Lys Pro Leu Gln Gln Glu Leu His Ser Leu
              20                  25                  30

 ggt gct gcc ctt gcg gag aag ctg gat cgg ctc gcc aca gcg ctg gca      144
 Gly Ala Ala Leu Ala Glu Lys Leu Asp Arg Leu Ala Thr Ala Leu Ala
          35                  40                  45

 ggc ctg gct cag gaa gtg gcc acc atg agg acc cag gga gcc tct cct      192
 Gly Leu Ala Gln Glu Val Ala Thr Met Arg Thr Gln Gly Ala Ser Pro
      50                  55                  60

 cct gca gcc agt gca gat gca gac gtg ccg acc tca gga gtg gca cca      240
 Pro Ala Ala Ser Ala Asp Ala Asp Val Pro Thr Ser Gly Val Ala Pro
  65                  70                  75                  80

 gac ggg atc cca gag cgg ccc aag gag ccg agc agc ctg ctg gga gga      288
 Asp Gly Ile Pro Glu Arg Pro Lys Glu Pro Ser Ser Leu Leu Gly Gly
                  85                  90                  95

 gtg cag agg gcc ctc cag gaa gaa ctg tgg ggt gag ggt tcc cag gga      336
 Val Gln Arg Ala Leu Gln Glu Glu Leu Trp Gly Glu Gly Ser Gln Gly
             100                 105                 110

 agg aca gga ttc cag tcc ttc cac cag cgt gga att gtg gcc gtg cgc      384
 Arg Thr Gly Phe Gln Ser Phe His Gln Arg Gly Ile Val Ala Val Arg
         115                 120                 125

 cct ctt ctg ggg gtc ttg cat act ccc tct gac tgt gaa ata caa gac      432
 Pro Leu Leu Gly Val Leu His Thr Pro Ser Asp Cys Glu Ile Gln Asp
     130                 135                 140

 ttg tct ctg gtt aaa aga cat ttc aag gat cag tct tta gag ccc aca      480
 Leu Ser Leu Val Lys Arg His Phe Lys Asp Gln Ser Leu Glu Pro Thr
 145                 150                 155                 160

 gaa tgc cac cta gca ctt aga ttc tct gct tca tgg aca tcg atg tct      528
 Glu Cys His Leu Ala Leu Arg Phe Ser Ala Ser Trp Thr Ser Met Ser
                 165                 170                 175

 cat ctc cag tca gac tgc agg ttc ctt aca gac agg tgg cat atg cta      576
 His Leu Gln Ser Asp Cys Arg Phe Leu Thr Asp Arg Trp His Met Leu
             180                 185                 190

 gac atc tct gtg cta ctc aca ggg act ggc aca ttc tgg gca cat act      624
 Asp Ile Ser Val Leu Leu Thr Gly Thr Gly Thr Phe Trp Ala His Thr
         195                 200                 205

 ggg gac att ctg ggc aca tac tgg gta ctc aat acc cgt tat aca ttc      672
 Gly Asp Ile Leu Gly Thr Tyr Trp Val Leu Asn Thr Arg Tyr Thr Phe
     210                 215                 220

 ttt ggg aag atc atc cgc tcc ccc ata gct tca gaa gca cat gcg gat      720
 Phe Gly Lys Ile Ile Arg Ser Pro Ile Ala Ser Glu Ala His Ala Asp
 225                 230                 235                 240

 agt tct cag ctg tat gtc tgc agc ctg gcc ctc tcc tga                  759
 Ser Ser Gln Leu Tyr Val Cys Ser Leu Ala Leu Ser 
                 245                 250





      <210> 114
      <211> 180
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(180)

      <400> 114
  atg cct gtg aat tat gct cta tgt tgg acc gtg ttt gtt ttg cca gag      48
  Met Pro Val Asn Tyr Ala Leu Cys Trp Thr Val Phe Val Leu Pro Glu
    1               5                  10                  15

 gct gca acc aga cct gtg ctg gaa cca cat tta gaa acc agt atg aca       96
 Ala Ala Thr Arg Pro Val Leu Glu Pro His Leu Glu Thr Ser Met Thr
              20                  25                  30

 atg ata tca ttg tct gga gca gga ttc atc aaa ctg aat atg caa tgg      144
 Met Ile Ser Leu Ser Gly Ala Gly Phe Ile Lys Leu Asn Met Gln Trp
          35                  40                  45

 aag ctg tta aac aag gtt cag cca cag ttg gtc tga                      180
 Lys Leu Leu Asn Lys Val Gln Pro Gln Leu Val 
      50                  55





      <210> 115
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 115
  atg tgc att gtg tac cta ctg tgt gac agg att gtg ctg gcc tca gag      48
  Met Cys Ile Val Tyr Leu Leu Cys Asp Arg Ile Val Leu Ala Ser Glu
    1               5                  10                  15

 cag gga tgc aaa gat gtc tct gcc cac cca cgc aac cca gac tat gaa       96
 Gln Gly Cys Lys Asp Val Ser Ala His Pro Arg Asn Pro Asp Tyr Glu
              20                  25                  30

 gag tcc ggt gaa agc agc agt agt gga ggc tct gag ctg gag cct tct      144
 Glu Ser Gly Glu Ser Ser Ser Ser Gly Gly Ser Glu Leu Glu Pro Ser
          35                  40                  45

 ggc cat cag ctc ttc tgc tta gaa tac gag gca gac agt gga gag gtc      192
 Gly His Gln Leu Phe Cys Leu Glu Tyr Glu Ala Asp Ser Gly Glu Val
      50                  55                  60

 aca tca gtt atc gtc tat cag ggt gat gac cca gga aag gtg agt gag      240
 Thr Ser Val Ile Val Tyr Gln Gly Asp Asp Pro Gly Lys Val Ser Glu
  65                  70                  75                  80

 aag gtg tcg gca cac acg cct ctg gat cca ccc atg cga gaa gcc ctc      288
 Lys Val Ser Ala His Thr Pro Leu Asp Pro Pro Met Arg Glu Ala Leu
                  85                  90                  95

 aag ttg cgt atc cag gag gag att gca aag cgc cag agc caa cac tga      336
 Lys Leu Arg Ile Gln Glu Glu Ile Ala Lys Arg Gln Ser Gln His 
             100                 105                 110





      <210> 116
      <211> 273
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(273)

      <400> 116
  atg cgc ata cga cga act ccc gca ctc agc ggg gca ggt ttc gtc ctt      48
  Met Arg Ile Arg Arg Thr Pro Ala Leu Ser Gly Ala Gly Phe Val Leu
    1               5                  10                  15

 cat ctt ctc agt cgg cag gac ctg ctt ctc tct gag gat gaa att ccc       96
 His Leu Leu Ser Arg Gln Asp Leu Leu Leu Ser Glu Asp Glu Ile Pro
              20                  25                  30

 agc ggc cgc ggg gaa agt tta cgg gat gta ggc ggc ggc ggc ggt agt      144
 Ser Gly Arg Gly Glu Ser Leu Arg Asp Val Gly Gly Gly Gly Gly Ser
          35                  40                  45

 ggt agc ggt tat tcg gcg gcc cgc ggc gga cca tgg ccc tgg ccc ggc      192
 Gly Ser Gly Tyr Ser Ala Ala Arg Gly Gly Pro Trp Pro Trp Pro Gly
      50                  55                  60

 gtc gct ggg ctt tcc tca cgg cgt ccc cga gca gcg tcg cag agc ggg      240
 Val Ala Gly Leu Ser Ser Arg Arg Pro Arg Ala Ala Ser Gln Ser Gly
  65                  70                  75                  80

 ccg act tcc ggg aag gaa ctg acc agc gac tga                          273
 Pro Thr Ser Gly Lys Glu Leu Thr Ser Asp 
                  85                  90





      <210> 117
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 117
  atg gta gtt ggg acc atc tca gga ttt ctc ttg cta gct gat cac aca      48
  Met Val Val Gly Thr Ile Ser Gly Phe Leu Leu Leu Ala Asp His Thr
    1               5                  10                  15

 atc ctt gag cat cat tta aat tat agc tat aga ggt ggc agt ata aga       96
 Ile Leu Glu His His Leu Asn Tyr Ser Tyr Arg Gly Gly Ser Ile Arg
              20                  25                  30

 gag aaa gat aat agc gta tct gaa gaa aat acg tcc ttc ttc ctc ctg      144
 Glu Lys Asp Asn Ser Val Ser Glu Glu Asn Thr Ser Phe Phe Leu Leu
          35                  40                  45

 aaa caa gaa gat gac tta gat ttt atc caa aga aag ctg caa att ctt      192
 Lys Gln Glu Asp Asp Leu Asp Phe Ile Gln Arg Lys Leu Gln Ile Leu
      50                  55                  60

 atc atc tta aca tta agg tct act aat aac ttt tat ctc aag tat aca      240
 Ile Ile Leu Thr Leu Arg Ser Thr Asn Asn Phe Tyr Leu Lys Tyr Thr
  65                  70                  75                  80

 cag tat gaa aca aaa ggg aac atg cca caa aaa act cca agg aac cat      288
 Gln Tyr Glu Thr Lys Gly Asn Met Pro Gln Lys Thr Pro Arg Asn His
                  85                  90                  95

 atg tat atc aaa ggg atg gcc aaa gag act tac tga                      324
 Met Tyr Ile Lys Gly Met Ala Lys Glu Thr Tyr 
             100                 105





      <210> 118
      <211> 300
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(300)

      <400> 118
  atg gcc cac tta gtc ttt ggc tcc ttt gct gtg agt ccc tac acc tgg      48
  Met Ala His Leu Val Phe Gly Ser Phe Ala Val Ser Pro Tyr Thr Trp
    1               5                  10                  15

 ttc ctg ttg tgc cca gag gca tgg gtc aca cag cag acc cat ggt aac       96
 Phe Leu Leu Cys Pro Glu Ala Trp Val Thr Gln Gln Thr His Gly Asn
              20                  25                  30

 cta ggg gac atc cgg aac ctg ctc atc tgg atc aag aag aat ttg cta      144
 Leu Gly Asp Ile Arg Asn Leu Leu Ile Trp Ile Lys Lys Asn Leu Leu
          35                  40                  45

 aaa gag cgg cca gag ttg ttc atc cag gga gac agc gtg cgg cca gga      192
 Lys Glu Arg Pro Glu Leu Phe Ile Gln Gly Asp Ser Val Arg Pro Gly
      50                  55                  60

 att ctg gtg ctg att aac gat gcc gac tgg gag cta ctg ggt gag ctg      240
 Ile Leu Val Leu Ile Asn Asp Ala Asp Trp Glu Leu Leu Gly Glu Leu
  65                  70                  75                  80

 gac tac cag ctt cag gac cag gac agc gtc ctc ttc atc tcc act ctg      288
 Asp Tyr Gln Leu Gln Asp Gln Asp Ser Val Leu Phe Ile Ser Thr Leu
                  85                  90                  95

 cac ggc ggc tga                                                      300
 His Gly Gly 






      <210> 119
      <211> 426
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(426)

      <400> 119
  atg cat ttt gaa agt gta cat agc tta gtt ttt tat agc att acc tct      48
  Met His Phe Glu Ser Val His Ser Leu Val Phe Tyr Ser Ile Thr Ser
    1               5                  10                  15

 att ttc tta ttt gct caa tat ctc att atc act tta tct aaa atc aca       96
 Ile Phe Leu Phe Ala Gln Tyr Leu Ile Ile Thr Leu Ser Lys Ile Thr
              20                  25                  30

 cga aat tcc tca gta cga aaa gca gaa ggg aaa aat cac agg ctt gag      144
 Arg Asn Ser Ser Val Arg Lys Ala Glu Gly Lys Asn His Arg Leu Glu
          35                  40                  45

 gta gtc tgg cct tat cct gat gaa aaa aaa att cag cag cag gat att      192
 Val Val Trp Pro Tyr Pro Asp Glu Lys Lys Ile Gln Gln Gln Asp Ile
      50                  55                  60

 aag cag gat ttc att tca gaa gtt atg gca gat gga ggt agt aag gta      240
 Lys Gln Asp Phe Ile Ser Glu Val Met Ala Asp Gly Gly Ser Lys Val
  65                  70                  75                  80

 gga cat atc ttt atc act aga gtc cag gta acc aat aat att gtc ctg      288
 Gly His Ile Phe Ile Thr Arg Val Gln Val Thr Asn Asn Ile Val Leu
                  85                  90                  95

 agc tgg att aat gaa gtg cag aag aaa agc aga agg cac aga ctg gag      336
 Ser Trp Ile Asn Glu Val Gln Lys Lys Ser Arg Arg His Arg Leu Glu
             100                 105                 110

 atc aaa tta gaa ggc aaa att gac caa acg gat gta ggg ggt gta cga      384
 Ile Lys Leu Glu Gly Lys Ile Asp Gln Thr Asp Val Gly Gly Val Arg
         115                 120                 125

 gga gga gat aat aga atg gtt tcc aat tcc aca ctt gac tga              426
 Gly Gly Asp Asn Arg Met Val Ser Asn Ser Thr Leu Asp 
     130                 135                 140





      <210> 120
      <211> 765
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(765)

      <400> 120
  atg tgg ggg att ggc tta ggc ctg gtc tgg ctg gcc ttc ctg gac cgc      48
  Met Trp Gly Ile Gly Leu Gly Leu Val Trp Leu Ala Phe Leu Asp Arg
    1               5                  10                  15

 agt ggc cag gag ctg aaa acc gtg acc cca gtc tcc ctg cag ctg ttc       96
 Ser Gly Gln Glu Leu Lys Thr Val Thr Pro Val Ser Leu Gln Leu Phe
              20                  25                  30

 ttg atg gga ttt ctg ttc gcc agt cag atg cat ttg cac agg act tgg      144
 Leu Met Gly Phe Leu Phe Ala Ser Gln Met His Leu His Arg Thr Trp
          35                  40                  45

 atc ctg aac tgt gta acc tgg aga ggc agg tgt gag cgg gcc atg ctg      192
 Ile Leu Asn Cys Val Thr Trp Arg Gly Arg Cys Glu Arg Ala Met Leu
      50                  55                  60

 ctg gcc cag cct gtg ccg gtg tct gtt tct gtt gtc tct cgg ccc ttc      240
 Leu Ala Gln Pro Val Pro Val Ser Val Ser Val Val Ser Arg Pro Phe
  65                  70                  75                  80

 tgt gag ccc tca gta aag ctc ttc gtg ctt cag tca gca agg aaa aac      288
 Cys Glu Pro Ser Val Lys Leu Phe Val Leu Gln Ser Ala Arg Lys Asn
                  85                  90                  95

 att ctt aag gta aaa caa tgg aaa cga gtt att tcc ttt gag gag gga      336
 Ile Leu Lys Val Lys Gln Trp Lys Arg Val Ile Ser Phe Glu Glu Gly
             100                 105                 110

 gga att gag tta ctt cag gcc cgg atg gat cca ccg ctg ctg acg tac      384
 Gly Ile Glu Leu Leu Gln Ala Arg Met Asp Pro Pro Leu Leu Thr Tyr
         115                 120                 125

 ttt ggt gct gac gta ctt tgg tgc cgt gac tcg gat aca ttc cct aga      432
 Phe Gly Ala Asp Val Leu Trp Cys Arg Asp Ser Asp Thr Phe Pro Arg
     130                 135                 140

 gaa cat ggg aac tgg gaa tcc gag aag aga tac cac ctt gtt gct agc      480
 Glu His Gly Asn Trp Glu Ser Glu Lys Arg Tyr His Leu Val Ala Ser
 145                 150                 155                 160

 atg ctc caa act gtg ata gac act gag aaa cag gcc act cta caa gct      528
 Met Leu Gln Thr Val Ile Asp Thr Glu Lys Gln Ala Thr Leu Gln Ala
                 165                 170                 175

 gca gag aga ttt ggg gat gag ctt tgc atc aca tgt agc atc agg aaa      576
 Ala Glu Arg Phe Gly Asp Glu Leu Cys Ile Thr Cys Ser Ile Arg Lys
             180                 185                 190

 ggg ggt gaa tat tat cca acc gga aga gaa gca gta cca gtg aat gac      624
 Gly Gly Glu Tyr Tyr Pro Thr Gly Arg Glu Ala Val Pro Val Asn Asp
         195                 200                 205

 cgt aaa tgg gac ccc aat cat gag atg gaa gcc ggg cgg agg aga cac      672
 Arg Lys Trp Asp Pro Asn His Glu Met Glu Ala Gly Arg Arg Arg His
     210                 215                 220

 ttt cag gtg tgc gta ata gaa ggc tta cgt aag act aag aac aag ttg      720
 Phe Gln Val Cys Val Ile Glu Gly Leu Arg Lys Thr Lys Asn Lys Leu
 225                 230                 235                 240

 tcc atg atc aac cag gaa ttt gat gaa aat cca atc gcc ttc tag          765
 Ser Met Ile Asn Gln Glu Phe Asp Glu Asn Pro Ile Ala Phe 
                 245                 250





      <210> 121
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 121
  atg gac atc agg acg cgg tgg ctc acg cca gta atc cta gca ctt tgg      48
  Met Asp Ile Arg Thr Arg Trp Leu Thr Pro Val Ile Leu Ala Leu Trp
    1               5                  10                  15

 gag gcc gag gga cac ttg gca ttc agg gac gtg gcc ata gaa ttc cct       96
 Glu Ala Glu Gly His Leu Ala Phe Arg Asp Val Ala Ile Glu Phe Pro
              20                  25                  30

 cag gag gag tgg aaa tgt ctg gac cct gct cag agg act tta tac agg      144
 Gln Glu Glu Trp Lys Cys Leu Asp Pro Ala Gln Arg Thr Leu Tyr Arg
          35                  40                  45

 gaa gtg atg gtg gag aac tac agg aac ctg gtc ttt ctg gga atc tgt      192
 Glu Val Met Val Glu Asn Tyr Arg Asn Leu Val Phe Leu Gly Ile Cys
      50                  55                  60

 ctt cct gac ctg agt gtt atc tcc atg ttg gag caa agg aga gat ccc      240
 Leu Pro Asp Leu Ser Val Ile Ser Met Leu Glu Gln Arg Arg Asp Pro
  65                  70                  75                  80

 cgg aat ctg cag agt gaa gtg aaa ata gca aac aat cca ggt ggc agg      288
 Arg Asn Leu Gln Ser Glu Val Lys Ile Ala Asn Asn Pro Gly Gly Arg
                  85                  90                  95

 gag tgc atc aaa ggt gtg aac gca gca cca ctc tgc ggg ttt ggg gta      336
 Glu Cys Ile Lys Gly Val Asn Ala Ala Pro Leu Cys Gly Phe Gly Val
             100                 105                 110

 aga cac ccg cat cgc gag aag cgc att ttc cgg ggg gtg gag ctg ggc      384
 Arg His Pro His Arg Glu Lys Arg Ile Phe Arg Gly Val Glu Leu Gly
         115                 120                 125

 agg caa gaa tac ccg gtg tca tag                                      408
 Arg Gln Glu Tyr Pro Val Ser 
     130                 135





      <210> 122
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 122
  atg att gga aag atc tgg ctc acc atc ctg ttc ata ttt cga atg ctt      48
  Met Ile Gly Lys Ile Trp Leu Thr Ile Leu Phe Ile Phe Arg Met Leu
    1               5                  10                  15

 gtt ctg ggt gta gca gct gaa gat gtc tgg aat gat gag cag tct ggc       96
 Val Leu Gly Val Ala Ala Glu Asp Val Trp Asn Asp Glu Gln Ser Gly
              20                  25                  30

 ttc atc tgc aat aca gaa caa cca ggc tgc aga aat gta tgc tac gac      144
 Phe Ile Cys Asn Thr Glu Gln Pro Gly Cys Arg Asn Val Cys Tyr Asp
          35                  40                  45

 cag gcc ttt cct atc tcc ctc att aga tac tgg gtt ctg cag gtg ata      192
 Gln Ala Phe Pro Ile Ser Leu Ile Arg Tyr Trp Val Leu Gln Val Ile
      50                  55                  60

 ttt gtg tct tca cca tcc ctg gtc tac atg ggc cat gca ttg tac cga      240
 Phe Val Ser Ser Pro Ser Leu Val Tyr Met Gly His Ala Leu Tyr Arg
  65                  70                  75                  80

 ctg aga gtt ctt gag gaa gag agg caa agg atg aaa gct cag tta aga      288
 Leu Arg Val Leu Glu Glu Glu Arg Gln Arg Met Lys Ala Gln Leu Arg
                  85                  90                  95

 gta gaa ctg gag gag gcc gcc gac tcg aag cgt gag cag ttc cgg agg      336
 Val Glu Leu Glu Glu Ala Ala Asp Ser Lys Arg Glu Gln Phe Arg Arg
             100                 105                 110

 tac ttg gag aag tcg ggg gtg ctg gac acg ctg acc aag gag caa ctg      384
 Tyr Leu Glu Lys Ser Gly Val Leu Asp Thr Leu Thr Lys Glu Gln Leu
         115                 120                 125

 gaa aaa tga                                                          393
 Glu Lys 
     130





      <210> 123
      <211> 633
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(633)

      <400> 123
  atg gga tgg ggg tgg ggg cat ctg tgc ctg agg agt gct gtg gcc tgc      48
  Met Gly Trp Gly Trp Gly His Leu Cys Leu Arg Ser Ala Val Ala Cys
    1               5                  10                  15

 ctg gca tgg gag gct tgg cgg tcc agc agg gac cca ggc cat tgc atc       96
 Leu Ala Trp Glu Ala Trp Arg Ser Ser Arg Asp Pro Gly His Cys Ile
              20                  25                  30

 acg cag gtg gcc ctg tcg gat cag ggc tcc cct ggg ctc cgc tcg gtc      144
 Thr Gln Val Ala Leu Ser Asp Gln Gly Ser Pro Gly Leu Arg Ser Val
          35                  40                  45

 ctc acg ctg ggg atg atg agc tcc tct cat gga ggg aag agc agc gac      192
 Leu Thr Leu Gly Met Met Ser Ser Ser His Gly Gly Lys Ser Ser Asp
      50                  55                  60

 aca gca aag gct gag gac cac ctg gga acc acg ctg agc cac ctg gac      240
 Thr Ala Lys Ala Glu Asp His Leu Gly Thr Thr Leu Ser His Leu Asp
  65                  70                  75                  80

 agg aca ggg cac agg gaa ctg tct ggt ctg gag gag gag acc tcc cag      288
 Arg Thr Gly His Arg Glu Leu Ser Gly Leu Glu Glu Glu Thr Ser Gln
                  85                  90                  95

 ggc tgt ggt ggg gag gag ggc cag cca cag agc cac tgc aaa tca tcc      336
 Gly Cys Gly Gly Glu Glu Gly Gln Pro Gln Ser His Cys Lys Ser Ser
             100                 105                 110

 ctg agg cca ggc gac tcg gaa gca gaa acc atg agc cca gca cgg ggc      384
 Leu Arg Pro Gly Asp Ser Glu Ala Glu Thr Met Ser Pro Ala Arg Gly
         115                 120                 125

 agt ggg agt gac aca act gga gca agt ttc cag gag gag aga aga att      432
 Ser Gly Ser Asp Thr Thr Gly Ala Ser Phe Gln Glu Glu Arg Arg Ile
     130                 135                 140

 cca gtg aag cag cag ctg cac gtc cga ggc ttg ggg agg acc cag gac      480
 Pro Val Lys Gln Gln Leu His Val Arg Gly Leu Gly Arg Thr Gln Asp
 145                 150                 155                 160

 tgt ctg aca gga tgg ggc cgc tgc ggg cga aag ctc tcc gga cga gcc      528
 Cys Leu Thr Gly Trp Gly Arg Cys Gly Arg Lys Leu Ser Gly Arg Ala
                 165                 170                 175

 ttc tcc cag gga gag gac ttc ttg ggt ccc ttc cag ctc tgg gac tct      576
 Phe Ser Gln Gly Glu Asp Phe Leu Gly Pro Phe Gln Leu Trp Asp Ser
             180                 185                 190

 ggg att ggg gtc atc gtg act cag cag ctg gag atg act cag gca ctg      624
 Gly Ile Gly Val Ile Val Thr Gln Gln Leu Glu Met Thr Gln Ala Leu
         195                 200                 205

 tcg gat tga                                                          633
 Ser Asp 
     210





      <210> 124
      <211> 1056
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1056)

      <400> 124
  atg ctg atg cca ggt ctc tct gcc tgc gtc cgg gac tgt gtt gcc ttc      48
  Met Leu Met Pro Gly Leu Ser Ala Cys Val Arg Asp Cys Val Ala Phe
    1               5                  10                  15

 ctt cag gca gtg gtc ctg ggg gat ccc agt cca gca gca cag tgt caa       96
 Leu Gln Ala Val Val Leu Gly Asp Pro Ser Pro Ala Ala Gln Cys Gln
              20                  25                  30

 gat acc tgg aca cta gca gca tcc gct gat ggt acc tgc aag gcc gtg      144
 Asp Thr Trp Thr Leu Ala Ala Ser Ala Asp Gly Thr Cys Lys Ala Val
          35                  40                  45

 ggc acg gag gat ggc tcg gtc tac ttc atc agc gta tat gat aag gaa      192
 Gly Thr Glu Asp Gly Ser Val Tyr Phe Ile Ser Val Tyr Asp Lys Glu
      50                  55                  60

 tcc cct cag gtc gtg cac aag gcc ttt ctc tcg gaa tcg tcc gtg cag      240
 Ser Pro Gln Val Val His Lys Ala Phe Leu Ser Glu Ser Ser Val Gln
  65                  70                  75                  80

 cac gtc gtt tat gat cag caa gga ata ttt ctg tta gtt gga aca gca      288
 His Val Val Tyr Asp Gln Gln Gly Ile Phe Leu Leu Val Gly Thr Ala
                  85                  90                  95

 gaa gga aaa gtc ttt att atc aat gcc aac tcc tca agc tca ttt cag      336
 Glu Gly Lys Val Phe Ile Ile Asn Ala Asn Ser Ser Ser Ser Phe Gln
             100                 105                 110

 att att gga ttc aca gag gtg gcc aaa gac att tta cag ata tcc aca      384
 Ile Ile Gly Phe Thr Glu Val Ala Lys Asp Ile Leu Gln Ile Ser Thr
         115                 120                 125

 gtg tct ctt tta gaa aca gac ata gtg gaa gtg atg gtg ctt tcc tcg      432
 Val Ser Leu Leu Glu Thr Asp Ile Val Glu Val Met Val Leu Ser Ser
     130                 135                 140

 ctt cca gaa gca ggg aga agc agg ttg gag atg ttc aca ctg cct aca      480
 Leu Pro Glu Ala Gly Arg Ser Arg Leu Glu Met Phe Thr Leu Pro Thr
 145                 150                 155                 160

 tta ctg cca caa gga agg ctg aaa gat gaa atc att ctt aag tac ctg      528
 Leu Leu Pro Gln Gly Arg Leu Lys Asp Glu Ile Ile Leu Lys Tyr Leu
                 165                 170                 175

 tat gag ttg gag cac gct ctg tcc tct gca gtc ttg ggc ttt caa agt      576
 Tyr Glu Leu Glu His Ala Leu Ser Ser Ala Val Leu Gly Phe Gln Ser
             180                 185                 190

 aac caa ata tat ggc ttc tgt agt caa gtg cca tac atc tgt agc tac      624
 Asn Gln Ile Tyr Gly Phe Cys Ser Gln Val Pro Tyr Ile Cys Ser Tyr
         195                 200                 205

 ctt ctt cct gaa gaa gaa cat acc ggt atc tac att ctt aaa cca tac      672
 Leu Leu Pro Glu Glu Glu His Thr Gly Ile Tyr Ile Leu Lys Pro Tyr
     210                 215                 220

 aaa aaa gta caa agc aga cag tat gga cct gga ctg ctc tat ctg tct      720
 Lys Lys Val Gln Ser Arg Gln Tyr Gly Pro Gly Leu Leu Tyr Leu Ser
 225                 230                 235                 240

 tca cat gga ttg tgg ctc ata aca ata gct aaa tgt gga att ctg tgt      768
 Ser His Gly Leu Trp Leu Ile Thr Ile Ala Lys Cys Gly Ile Leu Cys
                 245                 250                 255

 atc cga gac gtt tat act ttg ggt cat ggg att cag tca atg aga att      816
 Ile Arg Asp Val Tyr Thr Leu Gly His Gly Ile Gln Ser Met Arg Ile
             260                 265                 270

 tca atg gat gga caa aac att ctg gtg aat ggg aga gat gat ggc acc      864
 Ser Met Asp Gly Gln Asn Ile Leu Val Asn Gly Arg Asp Asp Gly Thr
         275                 280                 285

 ctt gtc tac cta aag tgg aag tac gta cag tat tca aca tgt ctg tct      912
 Leu Val Tyr Leu Lys Trp Lys Tyr Val Gln Tyr Ser Thr Cys Leu Ser
     290                 295                 300

 ttt tct acc atg tat cag aaa cag aag gca agc act gac tta tca caa      960
 Phe Ser Thr Met Tyr Gln Lys Gln Lys Ala Ser Thr Asp Leu Ser Gln
 305                 310                 315                 320

 gat gaa tta gtt cta acc gat gtt aag aag gaa att cct tgg ata caa     1008
 Asp Glu Leu Val Leu Thr Asp Val Lys Lys Glu Ile Pro Trp Ile Gln
                 325                 330                 335

 caa aaa agc caa gag gta ttt gtg aaa cat ggg gta ggt ttg aaa tag     1056
 Gln Lys Ser Gln Glu Val Phe Val Lys His Gly Val Gly Leu Lys 
             340                 345                 350





      <210> 125
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 125
  atg ccc tgt gaa tcc ttg aaa ctc aag gcc ttc ttt gtc aga gtt ttg      48
  Met Pro Cys Glu Ser Leu Lys Leu Lys Ala Phe Phe Val Arg Val Leu
    1               5                  10                  15

 gtt ctt act gca aag cta aac att act cag ctt gat ggt caa aca gca       96
 Val Leu Thr Ala Lys Leu Asn Ile Thr Gln Leu Asp Gly Gln Thr Ala
              20                  25                  30

 gaa ttg gcc cca act ggg agg cgg agt gaa tca ttg ctg tta gag gac      144
 Glu Leu Ala Pro Thr Gly Arg Arg Ser Glu Ser Leu Leu Leu Glu Asp
          35                  40                  45

 aag caa agg gaa cat tca gaa gga aag aat gaa aac aac aca gaa aga      192
 Lys Gln Arg Glu His Ser Glu Gly Lys Asn Glu Asn Asn Thr Glu Arg
      50                  55                  60

 ccc aga aag aac cag gga aat aca gag tac tct aat cac ttc tga          237
 Pro Arg Lys Asn Gln Gly Asn Thr Glu Tyr Ser Asn His Phe 
  65                  70                  75





      <210> 126
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 126
  atg ggg aga aat ctt aaa caa cat cag gca caa agg caa cag gtc cca      48
  Met Gly Arg Asn Leu Lys Gln His Gln Ala Gln Arg Gln Gln Val Pro
    1               5                  10                  15

 gta aca gct tta atg tta tgg gct tta att gga gca gcc cta gct ccg       96
 Val Thr Ala Leu Met Leu Trp Ala Leu Ile Gly Ala Ala Leu Ala Pro
              20                  25                  30

 tta cac aca caa gag cct aaa aag gga gat gag gag aaa atg tca cct      144
 Leu His Thr Gln Glu Pro Lys Lys Gly Asp Glu Glu Lys Met Ser Pro
          35                  40                  45

 gcc ata tca cct cct ctt ccc tca gcc cta ata tca cca ggc caa aat      192
 Ala Ile Ser Pro Pro Leu Pro Ser Ala Leu Ile Ser Pro Gly Gln Asn
      50                  55                  60

 aac aaa gag gaa acg gag gtt tta ccg gag cct cct cct cca ata gac      240
 Asn Lys Glu Glu Thr Glu Val Leu Pro Glu Pro Pro Pro Pro Ile Asp
  65                  70                  75                  80

 agg aaa aaa gac aga gga tat gct aca act atc agt ccc tgt ctt aag      288
 Arg Lys Lys Asp Arg Gly Tyr Ala Thr Thr Ile Ser Pro Cys Leu Lys
                  85                  90                  95

 cag gct gaa tta aaa gga tag                                          309
 Gln Ala Glu Leu Lys Gly 
             100





      <210> 127
      <211> 1107
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1107)

      <400> 127
  atg ttg tac tgg ctt atg cct aaa ggc aaa tta ctc tgg att gcc agt      48
  Met Leu Tyr Trp Leu Met Pro Lys Gly Lys Leu Leu Trp Ile Ala Ser
    1               5                  10                  15

 ttc cta acc agg cta caa ggg atc cag cat act cta ccc aga gta gag       96
 Phe Leu Thr Arg Leu Gln Gly Ile Gln His Thr Leu Pro Arg Val Glu
              20                  25                  30

 gaa aaa tct ata caa tca gta aaa gat gac aat atc tac cat ccg cac      144
 Glu Lys Ser Ile Gln Ser Val Lys Asp Asp Asn Ile Tyr His Pro His
          35                  40                  45

 cca aga ccc aga att gct gta gtt gga agc agc tcc aca gta att tcc      192
 Pro Arg Pro Arg Ile Ala Val Val Gly Ser Ser Ser Thr Val Ile Ser
      50                  55                  60

 tat agc cct ggg gag tat gct ttt acc aat ggc acc tct aga tgc cct      240
 Tyr Ser Pro Gly Glu Tyr Ala Phe Thr Asn Gly Thr Ser Arg Cys Pro
  65                  70                  75                  80

 tca ctc tct ctt gca gca ggg cca aga ctg ata acg aat ggc ccg tgg      288
 Ser Leu Ser Leu Ala Ala Gly Pro Arg Leu Ile Thr Asn Gly Pro Trp
                  85                  90                  95

 gaa gcg cac gaa gtc caa cgt gaa tca acg ata gca cta atg aaa ttg      336
 Glu Ala His Glu Val Gln Arg Glu Ser Thr Ile Ala Leu Met Lys Leu
             100                 105                 110

 ctt caa gtt cta gag cag aag gtg agg ctg aga gaa gga cat tca ctg      384
 Leu Gln Val Leu Glu Gln Lys Val Arg Leu Arg Glu Gly His Ser Leu
         115                 120                 125

 gga acc gtc aag atg tca aaa aat atc aat ccc atg ggc cat gtt tcc      432
 Gly Thr Val Lys Met Ser Lys Asn Ile Asn Pro Met Gly His Val Ser
     130                 135                 140

 aat cct cct acc tcc tac cca gac gaa ctc att acg aaa cag gtt tgt      480
 Asn Pro Pro Thr Ser Tyr Pro Asp Glu Leu Ile Thr Lys Gln Val Cys
 145                 150                 155                 160

 cct gga tcc cat cca aaa aga cct ggt gaa gtc aag cac aac gag gag      528
 Pro Gly Ser His Pro Lys Arg Pro Gly Glu Val Lys His Asn Glu Glu
                 165                 170                 175

 gtt ccc act tct cag gat aga gac act tgt aca acc caa gaa aca cag      576
 Val Pro Thr Ser Gln Asp Arg Asp Thr Cys Thr Thr Gln Glu Thr Gln
             180                 185                 190

 tac tca gtg aga aaa ata att tct gct gaa gat gat ttt aca gtc aaa      624
 Tyr Ser Val Arg Lys Ile Ile Ser Ala Glu Asp Asp Phe Thr Val Lys
         195                 200                 205

 aat tac aat cat ata agg aac aag ttc act ata cca tcc aga aag ggg      672
 Asn Tyr Asn His Ile Arg Asn Lys Phe Thr Ile Pro Ser Arg Lys Gly
     210                 215                 220

 cag caa gcc cac aga gcc tgg ctg aat aaa gcc att cct cag cca atg      720
 Gln Gln Ala His Arg Ala Trp Leu Asn Lys Ala Ile Pro Gln Pro Met
 225                 230                 235                 240

 cca act tca gca act tct ctg tta gca gct ctt gtt aga gct gca aag      768
 Pro Thr Ser Ala Thr Ser Leu Leu Ala Ala Leu Val Arg Ala Ala Lys
                 245                 250                 255

 cac cga aat caa cag ccc caa gac tta gct cag tcc tct tct cat cac      816
 His Arg Asn Gln Gln Pro Gln Asp Leu Ala Gln Ser Ser Ser His His
             260                 265                 270

 atc tac ctt ttc atc aca att aca ttt ggc agt ctt cgt gat tcc gag      864
 Ile Tyr Leu Phe Ile Thr Ile Thr Phe Gly Ser Leu Arg Asp Ser Glu
         275                 280                 285

 ctg aaa agc aaa aga ggc cct gac cct cag ctg tcg ctg gag ctc gag      912
 Leu Lys Ser Lys Arg Gly Pro Asp Pro Gln Leu Ser Leu Glu Leu Glu
     290                 295                 300

 atg gtg gcc aag gcg aaa gca gtc aag ccg gag aac tcc cga agg tgg      960
 Met Val Ala Lys Ala Lys Ala Val Lys Pro Glu Asn Ser Arg Arg Trp
 305                 310                 315                 320

 ttc tca ggt aac cag ctg ggc tca att ata aac agc cca aag aaa ggc     1008
 Phe Ser Gly Asn Gln Leu Gly Ser Ile Ile Asn Ser Pro Lys Lys Gly
                 325                 330                 335

 tct gct gtc ctg gag ggc acc ttt caa gag aaa caa aaa tgg gac gct     1056
 Ser Ala Val Leu Glu Gly Thr Phe Gln Glu Lys Gln Lys Trp Asp Ala
             340                 345                 350

 cgc tta aca aaa ggg gac tgt ttg gcc acc aac gtc ctg aac agg gtc     1104
 Arg Leu Thr Lys Gly Asp Cys Leu Ala Thr Asn Val Leu Asn Arg Val
         355                 360                 365

 tga                                                                 1107
 






      <210> 128
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 128
  atg tcg act gtt ttc aca gca gtc ccc tca ctg tgg ctg ggt gtg tcg      48
  Met Ser Thr Val Phe Thr Ala Val Pro Ser Leu Trp Leu Gly Val Ser
    1               5                  10                  15

 ggc gca gat gac agg cca cca caa cct gat tca gtc ccc act gtg gct       96
 Gly Ala Asp Asp Arg Pro Pro Gln Pro Asp Ser Val Pro Thr Val Ala
              20                  25                  30

 gtg tgt ggg ggg tca gat gac agg cta cca caa cct gat tca gtc ccc      144
 Val Cys Gly Gly Ser Asp Asp Arg Leu Pro Gln Pro Asp Ser Val Pro
          35                  40                  45

 act gtg gct gtg tgt cgg ggg tca aat gac agg cca cca caa cct gat      192
 Thr Val Ala Val Cys Arg Gly Ser Asn Asp Arg Pro Pro Gln Pro Asp
      50                  55                  60

 tca gtc ctc act gtg tct gtg tgt gtg ggt gca gat gac agg cca cca      240
 Ser Val Leu Thr Val Ser Val Cys Val Gly Ala Asp Asp Arg Pro Pro
  65                  70                  75                  80

 caa cct gat tca gga ttc agt tgg gct acc agc cag tgc cat aag gaa      288
 Gln Pro Asp Ser Gly Phe Ser Trp Ala Thr Ser Gln Cys His Lys Glu
                  85                  90                  95

 aac cat tct ggg gct ctt gag agg ggc aaa gca taa                      324
 Asn His Ser Gly Ala Leu Glu Arg Gly Lys Ala 
             100                 105





      <210> 129
      <211> 945
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(945)

      <400> 129
  atg gct gct tgc gtt atg ctc ctt cct ggt tta tct tct ctc atc tgt      48
  Met Ala Ala Cys Val Met Leu Leu Pro Gly Leu Ser Ser Leu Ile Cys
    1               5                  10                  15

 ttg cag gaa cct gac acc aca tct cca acg ccc tgc atc agg ggc cct       96
 Leu Gln Glu Pro Asp Thr Thr Ser Pro Thr Pro Cys Ile Arg Gly Pro
              20                  25                  30

 gaa gct ctc tgt ggt gaa gga cca ttc tgg cct ctc tca tct gtc gcc      144
 Glu Ala Leu Cys Gly Glu Gly Pro Phe Trp Pro Leu Ser Ser Val Ala
          35                  40                  45

 gat gga tat gtg gtc ctg cta cac atg act aga aca att tct aaa ttt      192
 Asp Gly Tyr Val Val Leu Leu His Met Thr Arg Thr Ile Ser Lys Phe
      50                  55                  60

 ctt aat aca ttt cag gag ttc ctg aca ata aaa gca tta gga agt gga      240
 Leu Asn Thr Phe Gln Glu Phe Leu Thr Ile Lys Ala Leu Gly Ser Gly
  65                  70                  75                  80

 agt gat aac agg gtt ggg tca ttt ctc agg caa cag aaa tgt ggc tgg      288
 Ser Asp Asn Arg Val Gly Ser Phe Leu Arg Gln Gln Lys Cys Gly Trp
                  85                  90                  95

 gtt cca cag gca gca gat gag aca cgg agg att tac tgc agg gtg act      336
 Val Pro Gln Ala Ala Asp Glu Thr Arg Arg Ile Tyr Cys Arg Val Thr
             100                 105                 110

 tac tta aat tca gaa aca gtt tct ggc aga tgt agg aat gaa aga cag      384
 Tyr Leu Asn Ser Glu Thr Val Ser Gly Arg Cys Arg Asn Glu Arg Gln
         115                 120                 125

 atc tcc aac aca tta tct ggt gtt ctt ccc atc ccc cac tca ctg att      432
 Ile Ser Asn Thr Leu Ser Gly Val Leu Pro Ile Pro His Ser Leu Ile
     130                 135                 140

 aat gct ggt ttt act gtg gag aaa cct tgg ttt ggt gta acc acc gaa      480
 Asn Ala Gly Phe Thr Val Glu Lys Pro Trp Phe Gly Val Thr Thr Glu
 145                 150                 155                 160

 gaa aat ttc cag aag gat gtc agg aca cat gaa cag gag aga tgg aat      528
 Glu Asn Phe Gln Lys Asp Val Arg Thr His Glu Gln Glu Arg Trp Asn
                 165                 170                 175

 ctc cgc act gca gaa aag cac aag gaa gaa cct gca atg gaa gaa atg      576
 Leu Arg Thr Ala Glu Lys His Lys Glu Glu Pro Ala Met Glu Glu Met
             180                 185                 190

 aac cca gag cgc cgc tcc agt tct tct ctt gca gtg ttt cat gaa ctg      624
 Asn Pro Glu Arg Arg Ser Ser Ser Ser Leu Ala Val Phe His Glu Leu
         195                 200                 205

 ggg gcc tat cga cat ctt tct gca att act aat ttc atg ctg aca tac      672
 Gly Ala Tyr Arg His Leu Ser Ala Ile Thr Asn Phe Met Leu Thr Tyr
     210                 215                 220

 caa ccc caa cac tgc ctg aat att aac cta acc cct gct ttt ata caa      720
 Gln Pro Gln His Cys Leu Asn Ile Asn Leu Thr Pro Ala Phe Ile Gln
 225                 230                 235                 240

 ata cgg ggt tgg att gtt gaa att gag ggt gaa gag ttg cag agt tac      768
 Ile Arg Gly Trp Ile Val Glu Ile Glu Gly Glu Glu Leu Gln Ser Tyr
                 245                 250                 255

 agc aaa cag aaa gcc tct caa aac ata gtt ggt ata tac aat gtc atg      816
 Ser Lys Gln Lys Ala Ser Gln Asn Ile Val Gly Ile Tyr Asn Val Met
             260                 265                 270

 cac aac caa agt gtg cag gtt tca gag aac ctg aga cta acg tgt gct      864
 His Asn Gln Ser Val Gln Val Ser Glu Asn Leu Arg Leu Thr Cys Ala
         275                 280                 285

 gca ggc tgt gca tat ttc aga cac ctc aaa cat caa aga ccc aaa gat      912
 Ala Gly Cys Ala Tyr Phe Arg His Leu Lys His Gln Arg Pro Lys Asp
     290                 295                 300

 gga act tac ttc tcg gac aaa att aaa aca tga                          945
 Gly Thr Tyr Phe Ser Asp Lys Ile Lys Thr 
 305                 310





      <210> 130
      <211> 549
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(549)

      <400> 130
  atg gcg gcc gtg gcg ctg gcg agc ggg aca cgc ctc ggc ctt gtc ctc      48
  Met Ala Ala Val Ala Leu Ala Ser Gly Thr Arg Leu Gly Leu Val Leu
    1               5                  10                  15

 gag ctg ctc ccg gga cag ccc gcg ctg ccc cgg gcg cgc cgg gag tca       96
 Glu Leu Leu Pro Gly Gln Pro Ala Leu Pro Arg Ala Arg Arg Glu Ser
              20                  25                  30

 gtg acc ttc gag gat gtg gcc gtc tac ttc tct gag aac gaa tgg atc      144
 Val Thr Phe Glu Asp Val Ala Val Tyr Phe Ser Glu Asn Glu Trp Ile
          35                  40                  45

 ggc ctg ggc cct gct cag aga gcc ctg tac agg gat gtg atg ctg gag      192
 Gly Leu Gly Pro Ala Gln Arg Ala Leu Tyr Arg Asp Val Met Leu Glu
      50                  55                  60

 aat tat ggg gct gtg gct tcc ctg gca gca ttc cca ttt ccg aaa ccg      240
 Asn Tyr Gly Ala Val Ala Ser Leu Ala Ala Phe Pro Phe Pro Lys Pro
  65                  70                  75                  80

 gct ctg att tcc cag ctg gag cga ggg gaa aca ccc tgg tgc tcg gtt      288
 Ala Leu Ile Ser Gln Leu Glu Arg Gly Glu Thr Pro Trp Cys Ser Val
                  85                  90                  95

 cct cgg gga gct ctg gat gga gag gcc cca agg ggc atc tcc tca gta      336
 Pro Arg Gly Ala Leu Asp Gly Glu Ala Pro Arg Gly Ile Ser Ser Val
             100                 105                 110

 gaa aag agc tgg gct ccc tca ctg ttt cct ggc aca cgg tat gat att      384
 Glu Lys Ser Trp Ala Pro Ser Leu Phe Pro Gly Thr Arg Tyr Asp Ile
         115                 120                 125

 gag ttc cat gat tat gca tgt acc ttg ggt tac aac ccc cct ggc ggc      432
 Glu Phe His Asp Tyr Ala Cys Thr Leu Gly Tyr Asn Pro Pro Gly Gly
     130                 135                 140

 aga acc tct att gtg tcc ttc ttt gta ttg ccc aca gag cct gtt ggt      480
 Arg Thr Ser Ile Val Ser Phe Phe Val Leu Pro Thr Glu Pro Val Gly
 145                 150                 155                 160

 gac ctg cac aca gga gcc ctc cag tca gta ctg att gaa tta ctc aag      528
 Asp Leu His Thr Gly Ala Leu Gln Ser Val Leu Ile Glu Leu Leu Lys
                 165                 170                 175

 gct gcc tct ctg caa agt tga                                          549
 Ala Ala Ser Leu Gln Ser 
             180





      <210> 131
      <211> 387
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(387)

      <400> 131
  atg gcc tgc agg gtc ctg caa ggt ctc ccc ttt gcc tgc ctg tcc agc      48
  Met Ala Cys Arg Val Leu Gln Gly Leu Pro Phe Ala Cys Leu Ser Ser
    1               5                  10                  15

 ccc atc tgt tcc cac tct gcc ctt act ctt gat cat tct ctc ctg tgc       96
 Pro Ile Cys Ser His Ser Ala Leu Thr Leu Asp His Ser Leu Leu Cys
              20                  25                  30

 ctg aac ttt ttc ttc aac cct tat gcc ctt ctg cct aac ttt tac tta      144
 Leu Asn Phe Phe Phe Asn Pro Tyr Ala Leu Leu Pro Asn Phe Tyr Leu
          35                  40                  45

 ttt ggc aag ttc cag ctc aga att cct tcc tct gga aag cct ttt ctg      192
 Phe Gly Lys Phe Gln Leu Arg Ile Pro Ser Ser Gly Lys Pro Phe Leu
      50                  55                  60

 act tcc gaa gac cag gac cct gct ggg atc ttt gag ctt gtg gag gtg      240
 Thr Ser Glu Asp Gln Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val
  65                  70                  75                  80

 gtc ggc aat gga acc tac gga cag gtg tac aag gtg aga cga atg gtg      288
 Val Gly Asn Gly Thr Tyr Gly Gln Val Tyr Lys Val Arg Arg Met Val
                  85                  90                  95

 tgg aag tat gac ctc cac atc tgc agg gca gtc ttg gga gga gtg gaa      336
 Trp Lys Tyr Asp Leu His Ile Cys Arg Ala Val Leu Gly Gly Val Glu
             100                 105                 110

 gga agt aga ttc ctg gtc tgc agg tct gaa ggg ggc tat ggg aga tgc      384
 Gly Ser Arg Phe Leu Val Cys Arg Ser Glu Gly Gly Tyr Gly Arg Cys
         115                 120                 125

 tag                                                                  387
 






      <210> 132
      <211> 432
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(432)

      <400> 132
  atg ctt tta ccg ctg ttc ctt ctc att cac acc gga atc ggg cca agc      48
  Met Leu Leu Pro Leu Phe Leu Leu Ile His Thr Gly Ile Gly Pro Ser
    1               5                  10                  15

 tac tca gcc agc gac cgc gca gag ccg agg ccc tcg cct ggg ggc aga       96
 Tyr Ser Ala Ser Asp Arg Ala Glu Pro Arg Pro Ser Pro Gly Gly Arg
              20                  25                  30

 ttg act gct cga att tgg atc aag ggt gtg aag gag gat gga ggg acc      144
 Leu Thr Ala Arg Ile Trp Ile Lys Gly Val Lys Glu Asp Gly Gly Thr
          35                  40                  45

 atg caa ggg gct gtc gac tgg gga gag ggg gtt gaa gat gcg cag gac      192
 Met Gln Gly Ala Val Asp Trp Gly Glu Gly Val Glu Asp Ala Gln Asp
      50                  55                  60

 gca tca ctg cga gcc ata agg ttg cag aca aat ggc att cgt cac gga      240
 Ala Ser Leu Arg Ala Ile Arg Leu Gln Thr Asn Gly Ile Arg His Gly
  65                  70                  75                  80

 att ccc tgg gtg gtt cgc ccg agc ctg gaa cgc cag ccc ctg gac cgt      288
 Ile Pro Trp Val Val Arg Pro Ser Leu Glu Arg Gln Pro Leu Asp Arg
                  85                  90                  95

 ggg tgg gtt tct gcc atc ctt gcc tgc ccg cct ccc cgt tgt cct gga      336
 Gly Trp Val Ser Ala Ile Leu Ala Cys Pro Pro Pro Arg Cys Pro Gly
             100                 105                 110

 ctg cga ccg gaa cgg cgg cca cgc atg cgc agt gtg cgg aga ggg tcc      384
 Leu Arg Pro Glu Arg Arg Pro Arg Met Arg Ser Val Arg Arg Gly Ser
         115                 120                 125

 aca acc tct gtc gca ggg caa agc caa gtt gag caa gga gga tgt tga      432
 Thr Thr Ser Val Ala Gly Gln Ser Gln Val Glu Gln Gly Gly Cys 
     130                 135                 140





      <210> 133
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 133
  atg agc agc gaa gtg gtg gct ctg ctg tgc tgg gca tgc agc acg tgc      48
  Met Ser Ser Glu Val Val Ala Leu Leu Cys Trp Ala Cys Ser Thr Cys
    1               5                  10                  15

 gac aga ctc ggg cag cag aga ggc gct ggt gaa gga caa ggt gct gga       96
 Asp Arg Leu Gly Gln Gln Arg Gly Ala Gly Glu Gly Gln Gly Ala Gly
              20                  25                  30

 ctt cct caa gag gat gcc gga gca gcc cca atg cgg ctt cag caa cac      144
 Leu Pro Gln Glu Asp Ala Gly Ala Ala Pro Met Arg Leu Gln Gln His
          35                  40                  45

 gct act gcc att gat aaa aac cct gcc tcc atc agc agc agg gcc aca      192
 Ala Thr Ala Ile Asp Lys Asn Pro Ala Ser Ile Ser Ser Arg Ala Thr
      50                  55                  60

 gca caa ctg cgt ggc ttt cca gtg tgc cac act gct gct gcc acc agg      240
 Ala Gln Leu Arg Gly Phe Pro Val Cys His Thr Ala Ala Ala Thr Arg
  65                  70                  75                  80

 gac cca agc gtg cgc cac tgg cag caa ctc tct gcc cct cag cag cac      288
 Asp Pro Ser Val Arg His Trp Gln Gln Leu Ser Ala Pro Gln Gln His
                  85                  90                  95

 agc ggc cat gca ctt gca cac act ctg aga act att tct gct gtt gcc      336
 Ser Gly His Ala Leu Ala His Thr Leu Arg Thr Ile Ser Ala Val Ala
             100                 105                 110

 acc aat gcc aga ggt tga                                              354
 Thr Asn Ala Arg Gly 
         115





      <210> 134
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 134
  atg cag gct gga ctc gcc cgg gcc atg gtc ctg gct gct ggc tgg tct      48
  Met Gln Ala Gly Leu Ala Arg Ala Met Val Leu Ala Ala Gly Trp Ser
    1               5                  10                  15

 agg gtg gcc tcg gct ggg gca gct ggc gac acc agt cct gtt cca aga       96
 Arg Val Ala Ser Ala Gly Ala Ala Gly Asp Thr Ser Pro Val Pro Arg
              20                  25                  30

 gcc ttg tct gat ctt cga atc acc cag aag tgt ggt ctc ctt gtc ccc      144
 Ala Leu Ser Asp Leu Arg Ile Thr Gln Lys Cys Gly Leu Leu Val Pro
          35                  40                  45

 aag gct gtt tcc tgg aag agc ctc ttt ctg ttc ccc atc acc gtg gaa      192
 Lys Ala Val Ser Trp Lys Ser Leu Phe Leu Phe Pro Ile Thr Val Glu
      50                  55                  60

 cta taa                                                              198
 Leu 
  65





      <210> 135
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 135
  atg gcc gct gcc gcc ctc ccg ccc cgg ccg ctg ctc ctt ctg ccg cta      48
  Met Ala Ala Ala Ala Leu Pro Pro Arg Pro Leu Leu Leu Leu Pro Leu
    1               5                  10                  15

 gtg ctg ctg ctg agc ggc cgc ccc acg cgc gcc gac agt aag ggg aag       96
 Val Leu Leu Leu Ser Gly Arg Pro Thr Arg Ala Asp Ser Lys Gly Lys
              20                  25                  30

 ctc ctg gca act gtt acc caa cga ctc cca ggc ttg cag caa gcc ctg      144
 Leu Leu Ala Thr Val Thr Gln Arg Leu Pro Gly Leu Gln Gln Ala Leu
          35                  40                  45

 ggc cac ggc ttt cac ggc ccg ctg ggg act ggg ggt ctt ctc tac ccg      192
 Gly His Gly Phe His Gly Pro Leu Gly Thr Gly Gly Leu Leu Tyr Pro
      50                  55                  60

 atg aac gca gcc gcg ctg gcc act cgc ctg gcc tct gat gtt ctt gcc      240
 Met Asn Ala Ala Ala Leu Ala Thr Arg Leu Ala Ser Asp Val Leu Ala
  65                  70                  75                  80

 agg gac cgg gtg cac ccc ctg gag gac tag                              270
 Arg Asp Arg Val His Pro Leu Glu Asp 
                  85





      <210> 136
      <211> 495
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(495)

      <400> 136
  atg gcg gcg gtt gtc gcg gcg acg agg tgg tgg cag ctg ttg ctt ggt      48
  Met Ala Ala Val Val Ala Ala Thr Arg Trp Trp Gln Leu Leu Leu Gly
    1               5                  10                  15

 gct cag cgc cgc gtg gat ggg ggc ctc ggc gcc cgc agc tcc cca aca       96
 Ala Gln Arg Arg Val Asp Gly Gly Leu Gly Ala Arg Ser Ser Pro Thr
              20                  25                  30

 tcc tgc tcc tgc tca tgg acg acg aat cac tcc cgc cac ctc ggg ccg      144
 Ser Cys Ser Cys Ser Trp Thr Thr Asn His Ser Arg His Leu Gly Pro
          35                  40                  45

 ccg ggt ccc ccc gct ggg ctc cag tct tac ctg acg gct gtc tct gtc      192
 Pro Gly Pro Pro Ala Gly Leu Gln Ser Tyr Leu Thr Ala Val Ser Val
      50                  55                  60

 ctc tgg aga atg ctg agc gaa gct gcc aca cct ggg ggg tta cac ctg      240
 Leu Trp Arg Met Leu Ser Glu Ala Ala Thr Pro Gly Gly Leu His Leu
  65                  70                  75                  80

 tcc cgc cgt gct cac gtt gtg tgt gag gac tgg gac gac acc gag tac      288
 Ser Arg Arg Ala His Val Val Cys Glu Asp Trp Asp Asp Thr Glu Tyr
                  85                  90                  95

 cag aca gtt ttg ggc cgt cgg tgt cgc tca gcc cct gtg tgc tgg ctc      336
 Gln Thr Val Leu Gly Arg Arg Cys Arg Ser Ala Pro Val Cys Trp Leu
             100                 105                 110

 cga cca gca gag acc ctg aca ggt gcc ttc aga ccc acc tgt gct gac      384
 Arg Pro Ala Glu Thr Leu Thr Gly Ala Phe Arg Pro Thr Cys Ala Asp
         115                 120                 125

 cag tgg ggg cca cgg cca cac cca agg gct ggg cag tcg tgg ctg tcg      432
 Gln Trp Gly Pro Arg Pro His Pro Arg Ala Gly Gln Ser Trp Leu Ser
     130                 135                 140

 gaa ttg gaa ggt gct ggt agt gta aaa tac aca gat tta gaa gac ttg      480
 Glu Leu Glu Gly Ala Gly Ser Val Lys Tyr Thr Asp Leu Glu Asp Leu
 145                 150                 155                 160

 gtg aaa gaa aaa taa                                                  495
 Val Lys Glu Lys 






      <210> 137
      <211> 1128
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1128)

      <400> 137
  atg ctc ctg cca atg ctg aga acc agc tgc agc acc ttc ctc aca gcg      48
  Met Leu Leu Pro Met Leu Arg Thr Ser Cys Ser Thr Phe Leu Thr Ala
    1               5                  10                  15

 ttg ctg gga ggg tca caa acc atg gga tgg acg acc gcg gcc agt ctt       96
 Leu Leu Gly Gly Ser Gln Thr Met Gly Trp Thr Thr Ala Ala Ser Leu
              20                  25                  30

 gac atg gga gca cca ggg caa tgc agg gcg tct aga gtt cag ggg caa      144
 Asp Met Gly Ala Pro Gly Gln Cys Arg Ala Ser Arg Val Gln Gly Gln
          35                  40                  45

 ggg acc gtg tcc agc ccc aag gag gga cag gac ttc aac gcc ttt tgc      192
 Gly Thr Val Ser Ser Pro Lys Glu Gly Gln Asp Phe Asn Ala Phe Cys
      50                  55                  60

 tgc tgc ctc ctg gcc ggt gct gaa gag gcc tca ggg cct cac agg gag      240
 Cys Cys Leu Leu Ala Gly Ala Glu Glu Ala Ser Gly Pro His Arg Glu
  65                  70                  75                  80

 aca cag gcc tca ctc cag ccc agc tct gag cca aat gaa gta gtc tgc      288
 Thr Gln Ala Ser Leu Gln Pro Ser Ser Glu Pro Asn Glu Val Val Cys
                  85                  90                  95

 tca gcg cag cag cag ttg cta cag ctc ctc aca ccc aga att cac ccc      336
 Ser Ala Gln Gln Gln Leu Leu Gln Leu Leu Thr Pro Arg Ile His Pro
             100                 105                 110

 aaa cgt cac agg gct ctc tct aga gga aac cag cca tct gtg ttc aag      384
 Lys Arg His Arg Ala Leu Ser Arg Gly Asn Gln Pro Ser Val Phe Lys
         115                 120                 125

 acg cac ccg gtc ctg cag gca gct ccc aca tcc agc aag gcc cag gcg      432
 Thr His Pro Val Leu Gln Ala Ala Pro Thr Ser Ser Lys Ala Gln Ala
     130                 135                 140

 agt gtg gcg ggt gaa gca gag ctg acc act gct cgc aac agc ccc tcc      480
 Ser Val Ala Gly Glu Ala Glu Leu Thr Thr Ala Arg Asn Ser Pro Ser
 145                 150                 155                 160

 cga ggc tca aag cca ccc gaa ccc act ctc ttc tgc gtc ttc agc gtg      528
 Arg Gly Ser Lys Pro Pro Glu Pro Thr Leu Phe Cys Val Phe Ser Val
                 165                 170                 175

 cag ctg cct gca cca aga cct gtc atc ggg cac ctc cca ctc gcc tcc      576
 Gln Leu Pro Ala Pro Arg Pro Val Ile Gly His Leu Pro Leu Ala Ser
             180                 185                 190

 atc acc cat caa ccc cca gca gtg atg gct gca gct ctg ggg atg ctt      624
 Ile Thr His Gln Pro Pro Ala Val Met Ala Ala Ala Leu Gly Met Leu
         195                 200                 205

 aac cct gac cgc cct tca cac gct gaa gac gcc cag aga cac cac aaa      672
 Asn Pro Asp Arg Pro Ser His Ala Glu Asp Ala Gln Arg His His Lys
     210                 215                 220

 cag agc cca gag cta tgg gag tac acg gcc tcc ttc ccc gag ttc cgc      720
 Gln Ser Pro Glu Leu Trp Glu Tyr Thr Ala Ser Phe Pro Glu Phe Arg
 225                 230                 235                 240

 ctg gag cca tcc aaa gtc tac ccc tcg gcc act tgc tca ctc aca ctg      768
 Leu Glu Pro Ser Lys Val Tyr Pro Ser Ala Thr Cys Ser Leu Thr Leu
                 245                 250                 255

 caa gga tgg cca caa acc acc acg ctc tgc acc ctg ggg aga cgg caa      816
 Gln Gly Trp Pro Gln Thr Thr Thr Leu Cys Thr Leu Gly Arg Arg Gln
             260                 265                 270

 caa caa agt ccc tca caa cac aac cac atg cag att gaa gaa gca aca      864
 Gln Gln Ser Pro Ser Gln His Asn His Met Gln Ile Glu Glu Ala Thr
         275                 280                 285

 atc aca gac ctg ggg agc cca gca cag agg gaa gcg gca gac gtg tct      912
 Ile Thr Asp Leu Gly Ser Pro Ala Gln Arg Glu Ala Ala Asp Val Ser
     290                 295                 300

 gca tcc cgg acc agc aca gag gga acc ggc aga ctt gtc tgc atc cca      960
 Ala Ser Arg Thr Ser Thr Glu Gly Thr Gly Arg Leu Val Cys Ile Pro
 305                 310                 315                 320

 gac cag cag cac cag aag ggc tca ccc gag cga tgg cct ggc aac gct     1008
 Asp Gln Gln His Gln Lys Gly Ser Pro Glu Arg Trp Pro Gly Asn Ala
                 325                 330                 335

 atg ccc agg gtg agg agg atg cac aga gcg tcc cac cct gag tgg tgt     1056
 Met Pro Arg Val Arg Arg Met His Arg Ala Ser His Pro Glu Trp Cys
             340                 345                 350

 ggg ctg gca gct cca aaa tca cgt cag atg cat gac ggc aga cgc acg     1104
 Gly Leu Ala Ala Pro Lys Ser Arg Gln Met His Asp Gly Arg Arg Thr
         355                 360                 365

 gca gca gag cgt gct aca cag tag                                     1128
 Ala Ala Glu Arg Ala Thr Gln 
     370                 375





      <210> 138
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 138
  atg gcc tct tct gcc ctg act ctg gga cag ctc ggc tgg ctt ggc cac      48
  Met Ala Ser Ser Ala Leu Thr Leu Gly Gln Leu Gly Trp Leu Gly His
    1               5                  10                  15

 gcc gcc tgg gct gcg cct cgc gct ggg gca tgc tcg ctg ctg acg gcc       96
 Ala Ala Trp Ala Ala Pro Arg Ala Gly Ala Cys Ser Leu Leu Thr Ala
              20                  25                  30

 ccg tgg ctt tgc ggg gct ctg tgc act gag aga ctg tat ccc ctc agt      144
 Pro Trp Leu Cys Gly Ala Leu Cys Thr Glu Arg Leu Tyr Pro Leu Ser
          35                  40                  45

 tgg cag gca gag ctc cgc ccc cgc ctc gcc tgc cgc gag cgc cgc cgg      192
 Trp Gln Ala Glu Leu Arg Pro Arg Leu Ala Cys Arg Glu Arg Arg Arg
      50                  55                  60

 cct ggc cgg gca agg tcc aga gag tgg aca ctg ggg aaa ggg tgg cag      240
 Pro Gly Arg Ala Arg Ser Arg Glu Trp Thr Leu Gly Lys Gly Trp Gln
  65                  70                  75                  80

 cta gga ccc agt gaa cct ggt gag gac ctg ctc agt gaa ggc ttc aac      288
 Leu Gly Pro Ser Glu Pro Gly Glu Asp Leu Leu Ser Glu Gly Phe Asn
                  85                  90                  95

 ccc ctg gca aaa ccc tcc tct gcc aaa agc cta ttg aac aag aag tcg      336
 Pro Leu Ala Lys Pro Ser Ser Ala Lys Ser Leu Leu Asn Lys Lys Ser
             100                 105                 110

 gat ggc ggt gtc aag gga atc ttc cta tcc ttg cta gtc tgc ttt aaa      384
 Asp Gly Gly Val Lys Gly Ile Phe Leu Ser Leu Leu Val Cys Phe Lys
         115                 120                 125

 cca gat gcc ttt gtg ctc aga aca gaa ggt tct gct ggc ctg aga ggg      432
 Pro Asp Ala Phe Val Leu Arg Thr Glu Gly Ser Ala Gly Leu Arg Gly
     130                 135                 140

 aag tag                                                              438
 Lys 
 145





      <210> 139
      <211> 558
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(558)

      <400> 139
  atg gag ccg cgg gcg ctc gtc acg gcg ctc agc ctc ggc ctc agc ctg      48
  Met Glu Pro Arg Ala Leu Val Thr Ala Leu Ser Leu Gly Leu Ser Leu
    1               5                  10                  15

 tgc tcc ctg ggg ctg ctc gtc acg gcc atc ttc acc gac cac tgg tac       96
 Cys Ser Leu Gly Leu Leu Val Thr Ala Ile Phe Thr Asp His Trp Tyr
              20                  25                  30

 gag acc gac ccc cgg cgc cac aag gag agc tgc gag cgc agc cgc gcg      144
 Glu Thr Asp Pro Arg Arg His Lys Glu Ser Cys Glu Arg Ser Arg Ala
          35                  40                  45

 ggc gcc gac ccc ccg gac cag aag aac cgc ctg atg ccg ctg tcg cac      192
 Gly Ala Asp Pro Pro Asp Gln Lys Asn Arg Leu Met Pro Leu Ser His
      50                  55                  60

 ctg ccg ctg cgg gac tcg ccc ccg ctg ggg cgc cgg ctg ctc ccg ggc      240
 Leu Pro Leu Arg Asp Ser Pro Pro Leu Gly Arg Arg Leu Leu Pro Gly
  65                  70                  75                  80

 ggc ccg ggg cgc gcc gac ccc gag tcc tgg cgc tcg ctc ctg ggg ctc      288
 Gly Pro Gly Arg Ala Asp Pro Glu Ser Trp Arg Ser Leu Leu Gly Leu
                  85                  90                  95

 ggc ggg ctg gac gcc gag tgc ggc cgg ccc ctc ttc gcc acc tac tcg      336
 Gly Gly Leu Asp Ala Glu Cys Gly Arg Pro Leu Phe Ala Thr Tyr Ser
             100                 105                 110

 ggc ctc tgg agg aag tgc tac ttc ctg ggc atc gac cgg gac atc gac      384
 Gly Leu Trp Arg Lys Cys Tyr Phe Leu Gly Ile Asp Arg Asp Ile Asp
         115                 120                 125

 acc ctc atc ctg aaa gac ttg ggt cgt gat tta gag atg cct gtg gag      432
 Thr Leu Ile Leu Lys Asp Leu Gly Arg Asp Leu Glu Met Pro Val Glu
     130                 135                 140

 ctg ctg gag gaa cta gac aca tgg gaa ata gtg ata aag gct gct aaa      480
 Leu Leu Glu Glu Leu Asp Thr Trp Glu Ile Val Ile Lys Ala Ala Lys
 145                 150                 155                 160

 gac aga ggg ccc tgc cct gac tgt cac ttc ctg ctg ctg cca cta atg      528
 Asp Arg Gly Pro Cys Pro Asp Cys His Phe Leu Leu Leu Pro Leu Met
                 165                 170                 175

 gct ttg gga ttt ggc ttc ttc cta cca tga                              558
 Ala Leu Gly Phe Gly Phe Phe Leu Pro 
             180                 185





      <210> 140
      <211> 732
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(732)

      <400> 140
  atg aat gtc aca agg aga tgg gca cgg agc tgc ttc ggg tgc atc acg      48
  Met Asn Val Thr Arg Arg Trp Ala Arg Ser Cys Phe Gly Cys Ile Thr
    1               5                  10                  15

 ctg ctc gtt cct gag gta tgg gaa ctg gcc ttt agt gaa gct atc cag       96
 Leu Leu Val Pro Glu Val Trp Glu Leu Ala Phe Ser Glu Ala Ile Gln
              20                  25                  30

 agc agg gca aat agc cac tgt caa tat tac atg ggt ctc aaa cag att      144
 Ser Arg Ala Asn Ser His Cys Gln Tyr Tyr Met Gly Leu Lys Gln Ile
          35                  40                  45

 cca cca aat gat ctt atc aat agt ctg aat gag aag cga cag aaa gaa      192
 Pro Pro Asn Asp Leu Ile Asn Ser Leu Asn Glu Lys Arg Gln Lys Glu
      50                  55                  60

 gaa gtg ttt tgt gac cgc aga tat gct gat ggg ctt cga cgc ccg gac      240
 Glu Val Phe Cys Asp Arg Arg Tyr Ala Asp Gly Leu Arg Arg Pro Asp
  65                  70                  75                  80

 ccc cag ggg aag ggt caa cag ctc gga cgt cga gct gtt cca ctc tat      288
 Pro Gln Gly Lys Gly Gln Gln Leu Gly Arg Arg Ala Val Pro Leu Tyr
                  85                  90                  95

 cgc ttc cca agg aag cgg gct agg ggt aac ggg cac ggt tgg tgg gtt      336
 Arg Phe Pro Arg Lys Arg Ala Arg Gly Asn Gly His Gly Trp Trp Val
             100                 105                 110

 tgc ccc cag cag agg cta gcg gtg gcg att agg agt cca gat gtc ttg      384
 Cys Pro Gln Gln Arg Leu Ala Val Ala Ile Arg Ser Pro Asp Val Leu
         115                 120                 125

 ggt ata gcc gtc gcc ccg gga aag tgg gct cta gac gca gga gtt ggc      432
 Gly Ile Ala Val Ala Pro Gly Lys Trp Ala Leu Asp Ala Gly Val Gly
     130                 135                 140

 aag ccc tct ctg ggg gca cgc gtg gct ggg gca gag ggc cgc aga ggc      480
 Lys Pro Ser Leu Gly Ala Arg Val Ala Gly Ala Glu Gly Arg Arg Gly
 145                 150                 155                 160

 ggg aag ctg gcc gga gag gag tgg gaa ggc gac caa ggg cag cag cag      528
 Gly Lys Leu Ala Gly Glu Glu Trp Glu Gly Asp Gln Gly Gln Gln Gln
                 165                 170                 175

 ggg ctc ctg cgg ggc gca gta gag gaa ctt tca cca ggt cgt gga aaa      576
 Gly Leu Leu Arg Gly Ala Val Glu Glu Leu Ser Pro Gly Arg Gly Lys
             180                 185                 190

 gac caa gcc act agc ccc aaa gag ccg gac ttc tcg cca agc gcc gga      624
 Asp Gln Ala Thr Ser Pro Lys Glu Pro Asp Phe Ser Pro Ser Ala Gly
         195                 200                 205

 gtc cct gaa cca gga tat gtg ggc act gct ccc tgc aag gtg tcg ata      672
 Val Pro Glu Pro Gly Tyr Val Gly Thr Ala Pro Cys Lys Val Ser Ile
     210                 215                 220

 atg cag gta cgt gaa gac aca cgc att tcc aaa aga aca gac cta aat      720
 Met Gln Val Arg Glu Asp Thr Arg Ile Ser Lys Arg Thr Asp Leu Asn
 225                 230                 235                 240

 gca gaa ctt tag                                                      732
 Ala Glu Leu 






      <210> 141
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 141
  atg aag aca aaa tac tca gaa gtt gca ttt gcc atg gcc act ggc tcc      48
  Met Lys Thr Lys Tyr Ser Glu Val Ala Phe Ala Met Ala Thr Gly Ser
    1               5                  10                  15

 agc tgg ggt ttg gtg cca gtg tta tta cag ggt ctg cgg agt atc agc       96
 Ser Trp Gly Leu Val Pro Val Leu Leu Gln Gly Leu Arg Ser Ile Ser
              20                  25                  30

 cat tgg ctt ggc ctc tct ctg ttc ctc cct ctg cac cta gaa ctc tta      144
 His Trp Leu Gly Leu Ser Leu Phe Leu Pro Leu His Leu Glu Leu Leu
          35                  40                  45

 tcc ttc ctg tgg ttt ggt gcc gac tgg gtc gga tct ggg ctt aga gta      192
 Ser Phe Leu Trp Phe Gly Ala Asp Trp Val Gly Ser Gly Leu Arg Val
      50                  55                  60

 ata gct ttg ggc atc cct agt gaa ggg gca aac ctg aga ttt ctc cgt      240
 Ile Ala Leu Gly Ile Pro Ser Glu Gly Ala Asn Leu Arg Phe Leu Arg
  65                  70                  75                  80

 gga cct gac agc caa ggc agg gca ctg tct cct gag gcc agt gcc agc      288
 Gly Pro Asp Ser Gln Gly Arg Ala Leu Ser Pro Glu Ala Ser Ala Ser
                  85                  90                  95

 acg tgc atg gtt cac aga aaa gga tcc tgg gct cag aat ctc gag aac      336
 Thr Cys Met Val His Arg Lys Gly Ser Trp Ala Gln Asn Leu Glu Asn
             100                 105                 110

 cgc ctg ctc cta aca att cag caa agg cag cca gta tta cac agc ccc      384
 Arg Leu Leu Leu Thr Ile Gln Gln Arg Gln Pro Val Leu His Ser Pro
         115                 120                 125

 tct ctg tgt tgt gac cct agc ttg ctg ctt ctg gct gtg cca aat gct      432
 Ser Leu Cys Cys Asp Pro Ser Leu Leu Leu Leu Ala Val Pro Asn Ala
     130                 135                 140

 aag cag gcg ttt cac tca ggg cag ccc ggg agg caa ggt ctg aga gtg      480
 Lys Gln Ala Phe His Ser Gly Gln Pro Gly Arg Gln Gly Leu Arg Val
 145                 150                 155                 160

 gaa gct cct ggg agc ctg agc tct ctc tgc ctc tcg tta gct gtg gct      528
 Glu Ala Pro Gly Ser Leu Ser Ser Leu Cys Leu Ser Leu Ala Val Ala
                 165                 170                 175

 ttg gcc atc aac tgg aac tat gtc att att tat aaa aca gga gca atc      576
 Leu Ala Ile Asn Trp Asn Tyr Val Ile Ile Tyr Lys Thr Gly Ala Ile
             180                 185                 190

 aca ggg ctg tgg caa gac tgg ccc acc cgg gtg act gcc tgc ttt cat      624
 Thr Gly Leu Trp Gln Asp Trp Pro Thr Arg Val Thr Ala Cys Phe His
         195                 200                 205

 caa cct aaa tgg aca ggg cga gag tgt gga ccc agt gct agg atc tgg      672
 Gln Pro Lys Trp Thr Gly Arg Glu Cys Gly Pro Ser Ala Arg Ile Trp
     210                 215                 220

 gag agg cga tgg ggc atg gag agc cat gca gag gtg gag ggc aag atg      720
 Glu Arg Arg Trp Gly Met Glu Ser His Ala Glu Val Glu Gly Lys Met
 225                 230                 235                 240

 gac ctg gat gcc att tca gag tga                                      744
 Asp Leu Asp Ala Ile Ser Glu 
                 245





      <210> 142
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(498)

      <400> 142
  atg cca cac tgc agc aga gtt tct ctc ctg tca cta ctc agt ctc ctg      48
  Met Pro His Cys Ser Arg Val Ser Leu Leu Ser Leu Leu Ser Leu Leu
    1               5                  10                  15

 cca ggg acc ccc act ggt caa ctg gaa gcc agc ctg caa gga gct gga       96
 Pro Gly Thr Pro Thr Gly Gln Leu Glu Ala Ser Leu Gln Gly Ala Gly
              20                  25                  30

 gca tat cct ccg ttg gaa gga aga aag aag aca aac agc agc ctg cat      144
 Ala Tyr Pro Pro Leu Glu Gly Arg Lys Lys Thr Asn Ser Ser Leu His
          35                  40                  45

 gct ttt gaa gct gga cta tca aca aag gat ctt ctc aat caa ttc acc      192
 Ala Phe Glu Ala Gly Leu Ser Thr Lys Asp Leu Leu Asn Gln Phe Thr
      50                  55                  60

 act agc aac aga atg cag gcg gtt ctc aga aat ggc tca caa aga agc      240
 Thr Ser Asn Arg Met Gln Ala Val Leu Arg Asn Gly Ser Gln Arg Ser
  65                  70                  75                  80

 aca gag aaa ggc tgt ctg aag gca gaa gca gga gat gtt tcc ctc ctg      288
 Thr Glu Lys Gly Cys Leu Lys Ala Glu Ala Gly Asp Val Ser Leu Leu
                  85                  90                  95

 aag atg gaa att gga cct tca agc ttt tct gtg gag tca gaa gtg cca      336
 Lys Met Glu Ile Gly Pro Ser Ser Phe Ser Val Glu Ser Glu Val Pro
             100                 105                 110

 cgg cca tct cag tgc ggc ctc tgc cag cac gag gcc caa ccg gca gtg      384
 Arg Pro Ser Gln Cys Gly Leu Cys Gln His Glu Ala Gln Pro Ala Val
         115                 120                 125

 tcc acc agc aga gga aca aga agc att gag gag gag tac cag ctt gag      432
 Ser Thr Ser Arg Gly Thr Arg Ser Ile Glu Glu Glu Tyr Gln Leu Glu
     130                 135                 140

 cag ctg cca gtg cca tct gca cat tcc acc ggc aga gga gac aga agc      480
 Gln Leu Pro Val Pro Ser Ala His Ser Thr Gly Arg Gly Asp Arg Ser
 145                 150                 155                 160

 agc ctc aaa tcc cat tga                                              498
 Ser Leu Lys Ser His 
                 165





      <210> 143
      <211> 246
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(246)

      <400> 143
  atg tct agg agc tcg aag gtg gtg ctg ggc ctc tcg gtg ctg ctg acg      48
  Met Ser Arg Ser Ser Lys Val Val Leu Gly Leu Ser Val Leu Leu Thr
    1               5                  10                  15

 gcg gcc aca gtg gcc ggc gta cat gtg aag cag cag tgg gac cag cag       96
 Ala Ala Thr Val Ala Gly Val His Val Lys Gln Gln Trp Asp Gln Gln
              20                  25                  30

 agg ctt cgt gac gga gtt atc aga gac att gag agg caa att cgg aaa      144
 Arg Leu Arg Asp Gly Val Ile Arg Asp Ile Glu Arg Gln Ile Arg Lys
          35                  40                  45

 aaa gaa aac att cgt ctt ttg gga gaa cag att att ttg act gag caa      192
 Lys Glu Asn Ile Arg Leu Leu Gly Glu Gln Ile Ile Leu Thr Glu Gln
      50                  55                  60

 ctt gaa gca gaa aga gag aag atg tta ttg gca aaa gga tct caa aaa      240
 Leu Glu Ala Glu Arg Glu Lys Met Leu Leu Ala Lys Gly Ser Gln Lys
  65                  70                  75                  80

 tca tga                                                              246
 Ser 






      <210> 144
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 144
  atg ggc cgg gtc tca ggg ctt gtg ccc tct cgc ttc ctg acg ctc ctg      48
  Met Gly Arg Val Ser Gly Leu Val Pro Ser Arg Phe Leu Thr Leu Leu
    1               5                  10                  15

 gcg cat ctg gtg gtc gtc atc acc tta ttc tgg tcc cgg gac agc aac       96
 Ala His Leu Val Val Val Ile Thr Leu Phe Trp Ser Arg Asp Ser Asn
              20                  25                  30

 ata cag gcc tgc ctg cct ctc acg ttc acc ccc gag gag tat gac aag      144
 Ile Gln Ala Cys Leu Pro Leu Thr Phe Thr Pro Glu Glu Tyr Asp Lys
          35                  40                  45

 cag gac att cag ctg gtg gcc gcg ctc tct gtc acc ctg ggc ctc ttt      192
 Gln Asp Ile Gln Leu Val Ala Ala Leu Ser Val Thr Leu Gly Leu Phe
      50                  55                  60

 gca gtg gag ctg gcc ggt ttc ctc tca gga gtc tcc atg ttc aac agc      240
 Ala Val Glu Leu Ala Gly Phe Leu Ser Gly Val Ser Met Phe Asn Ser
  65                  70                  75                  80

 acc cag agc ctc atc tgt atc ctt tct gcc tgc cca cct ttc cca cac      288
 Thr Gln Ser Leu Ile Cys Ile Leu Ser Ala Cys Pro Pro Phe Pro His
                  85                  90                  95

 gac cca ctt cta tca gga ctc cct tca gcc acc tga                      324
 Asp Pro Leu Leu Ser Gly Leu Pro Ser Ala Thr 
             100                 105





      <210> 145
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 145
  atg cag ctg caa gga ctg tca aat tat tgc aaa gcc cag tgt ggt ctg      48
  Met Gln Leu Gln Gly Leu Ser Asn Tyr Cys Lys Ala Gln Cys Gly Leu
    1               5                  10                  15

 atc caa atc caa gca cta ctc ctg tct gct ctg cct tgg gaa gtt gcc       96
 Ile Gln Ile Gln Ala Leu Leu Leu Ser Ala Leu Pro Trp Glu Val Ala
              20                  25                  30

 ctg tac tgc ctt ggc cca gag agc aac act cag gaa ctc agc aac tac      144
 Leu Tyr Cys Leu Gly Pro Glu Ser Asn Thr Gln Glu Leu Ser Asn Tyr
          35                  40                  45

 cta cca gac ttt ggc cat gtg tga                                      168
 Leu Pro Asp Phe Gly His Val 
      50                  55





      <210> 146
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 146
  atg ctc ctg ctg ccc tgg ttg aca gca ggg tgg acg ctg atc ttg tgc      48
  Met Leu Leu Leu Pro Trp Leu Thr Ala Gly Trp Thr Leu Ile Leu Cys
    1               5                  10                  15

 acc gac ctg ccc acc cct caa atg cct tta cca tac tgg cac tac cga       96
 Thr Asp Leu Pro Thr Pro Gln Met Pro Leu Pro Tyr Trp His Tyr Arg
              20                  25                  30

 cct tac aga cat ctc aca gcc cca agg gac cag aca gtg aca gac tgc      144
 Pro Tyr Arg His Leu Thr Ala Pro Arg Asp Gln Thr Val Thr Asp Cys
          35                  40                  45

 acc att gtg atg tcc acc ctg aga gag gag gct gcc cta gaa ttc atc      192
 Thr Ile Val Met Ser Thr Leu Arg Glu Glu Ala Ala Leu Glu Phe Ile
      50                  55                  60

 acc cag cga tgc cca gct tgg gtg ggt act ggg aag aag gag tgt agc      240
 Thr Gln Arg Cys Pro Ala Trp Val Gly Thr Gly Lys Lys Glu Cys Ser
  65                  70                  75                  80

 gtc aag tca aac ctg gtt gtg ccg agc gac aag cat ctc cca atc aca      288
 Val Lys Ser Asn Leu Val Val Pro Ser Asp Lys His Leu Pro Ile Thr
                  85                  90                  95

 ggg gcc tcc acc acc gta gcc ggc ctt ctt atc cag gcc aca cgt cta      336
 Gly Ala Ser Thr Thr Val Ala Gly Leu Leu Ile Gln Ala Thr Arg Leu
             100                 105                 110

 cct gct gga gca ggc ttg cct ggg aca ctg cca acc acc gtg gca gag      384
 Pro Ala Gly Ala Gly Leu Pro Gly Thr Leu Pro Thr Thr Val Ala Glu
         115                 120                 125

 gga agg aca gtc ctg gag ggg cct gtg tct ggc aat gaa atc ctc cag      432
 Gly Arg Thr Val Leu Glu Gly Pro Val Ser Gly Asn Glu Ile Leu Gln
     130                 135                 140

 atc tag                                                              438
 Ile 
 145





      <210> 147
      <211> 630
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(630)

      <400> 147
  atg ctg cct gtg gcg cct gtc tgg gtt tgc ggc tgt gca gcc agc ttg      48
  Met Leu Pro Val Ala Pro Val Trp Val Cys Gly Cys Ala Ala Ser Leu
    1               5                  10                  15

 gcc gca gag gca gcc cat ggc ttc ctg cag gga aga gac tgg gct gtg       96
 Ala Ala Glu Ala Ala His Gly Phe Leu Gln Gly Arg Asp Trp Ala Val
              20                  25                  30

 ggg gtg aaa tgg agc agg aag gct caa gct gcc ttt cct ggc aga agg      144
 Gly Val Lys Trp Ser Arg Lys Ala Gln Ala Ala Phe Pro Gly Arg Arg
          35                  40                  45

 gag agt ata aca gag aca aga gtg gca gag gct gcc cat gtc agc aag      192
 Glu Ser Ile Thr Glu Thr Arg Val Ala Glu Ala Ala His Val Ser Lys
      50                  55                  60

 ccc cag atg gca agg agt gcg ggt gaa aca ctc cgg gac cat gga gcg      240
 Pro Gln Met Ala Arg Ser Ala Gly Glu Thr Leu Arg Asp His Gly Ala
  65                  70                  75                  80

 agg gga aac tgc aaa gca ggc aga ggg aca cgg cct agc tac tgt cca      288
 Arg Gly Asn Cys Lys Ala Gly Arg Gly Thr Arg Pro Ser Tyr Cys Pro
                  85                  90                  95

 gaa gcc ttg gtc atg gct ggg gcc cga ctg gcc aga gca tac aac ggc      336
 Glu Ala Leu Val Met Ala Gly Ala Arg Leu Ala Arg Ala Tyr Asn Gly
             100                 105                 110

 tgt ctg gag gag gct ggc agg cct cag cgc tgg ttt gtc acc ctt agg      384
 Cys Leu Glu Glu Ala Gly Arg Pro Gln Arg Trp Phe Val Thr Leu Arg
         115                 120                 125

 agg gca atg gtc aca agc cca gat gcc ttc tgg agc tgg cag gcc aag      432
 Arg Ala Met Val Thr Ser Pro Asp Ala Phe Trp Ser Trp Gln Ala Lys
     130                 135                 140

 tgt cag gga cac cag agg gag ggc aaa gag ttt gag ttg gat ttc ttt      480
 Cys Gln Gly His Gln Arg Glu Gly Lys Glu Phe Glu Leu Asp Phe Phe
 145                 150                 155                 160

 gac ctg caa ccg aat gcg tcc tcc cta ata tat tct tgc acc aga gtg      528
 Asp Leu Gln Pro Asn Ala Ser Ser Leu Ile Tyr Ser Cys Thr Arg Val
                 165                 170                 175

 tac atc ctc agt gag tgc ctg agg gag tgt ggg gag gga att cct gca      576
 Tyr Ile Leu Ser Glu Cys Leu Arg Glu Cys Gly Glu Gly Ile Pro Ala
             180                 185                 190

 aag cag agt gag ggc tat gca agc cca tca gac cag ctg ctg gcc agc      624
 Lys Gln Ser Glu Gly Tyr Ala Ser Pro Ser Asp Gln Leu Leu Ala Ser
         195                 200                 205

 ctg tga                                                              630
 Leu 






      <210> 148
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 148
  atg gag ctc gcc atc ctt gtg tta att gta cgt gta ata att cat ctc      48
  Met Glu Leu Ala Ile Leu Val Leu Ile Val Arg Val Ile Ile His Leu
    1               5                  10                  15

 aac att gag aaa ggg cct cag agg aag aag aaa cct gag tgc cgt aca       96
 Asn Ile Glu Lys Gly Pro Gln Arg Lys Lys Lys Pro Glu Cys Arg Thr
              20                  25                  30

 gct cat gcc atc cag cag gtc aag ttt atg aag cac gtc acg gtc acc      144
 Ala His Ala Ile Gln Gln Val Lys Phe Met Lys His Val Thr Val Thr
          35                  40                  45

 tgc cga cat ggc act gtc tgg gtt gtg tct ccc atc gtg aag cct gcc      192
 Cys Arg His Gly Thr Val Trp Val Val Ser Pro Ile Val Lys Pro Ala
      50                  55                  60

 cca gac atc gta ctc gca gct ggc cgg aac agg acc gtg gaa gtg ttt      240
 Pro Asp Ile Val Leu Ala Ala Gly Arg Asn Arg Thr Val Glu Val Phe
  65                  70                  75                  80

 gac ctc aac gcc ggc tgc agt gca gcg gtg ata gcg gaa gcc cac tca      288
 Asp Leu Asn Ala Gly Cys Ser Ala Ala Val Ile Ala Glu Ala His Ser
                  85                  90                  95

 cgg cct gtc cat caa atc tgc caa aat aaa gtg agt aag ttt ttg gat      336
 Arg Pro Val His Gln Ile Cys Gln Asn Lys Val Ser Lys Phe Leu Asp
             100                 105                 110

 aac atg tat cat ctg taa                                              354
 Asn Met Tyr His Leu 
         115





      <210> 149
      <211> 1299
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1299)

      <400> 149
  atg tgg atg ctt tta cct gcc cta gtt ctg tgt ctg gac cca cag gga      48
  Met Trp Met Leu Leu Pro Ala Leu Val Leu Cys Leu Asp Pro Gln Gly
    1               5                  10                  15

 cca cct agg cca ggc ctt tat tcc cag acc ccg agg cta ctt ggg ggt       96
 Pro Pro Arg Pro Gly Leu Tyr Ser Gln Thr Pro Arg Leu Leu Gly Gly
              20                  25                  30

 ccg gat aag ggt gtg gta tac ggg ctt gac gat gag gtg cag gtg cag      144
 Pro Asp Lys Gly Val Val Tyr Gly Leu Asp Asp Glu Val Gln Val Gln
          35                  40                  45

 ggc gtt ctc aac cag gta ctc gga gtt gcg ccg ctg cag gtc ggc gtg      192
 Gly Val Leu Asn Gln Val Leu Gly Val Ala Pro Leu Gln Val Gly Val
      50                  55                  60

 cgc cag gaa gtc gcc ggc ctc ctc gct gct ctg gtg gaa gct gta ggc      240
 Arg Gln Glu Val Ala Gly Leu Leu Ala Ala Leu Val Glu Ala Val Gly
  65                  70                  75                  80

 gtg gcg gac cag cag gcg gcc ctg ctg gcg cgc ccc cac cag cac cgt      288
 Val Ala Asp Gln Gln Ala Ala Leu Leu Ala Arg Pro His Gln His Arg
                  85                  90                  95

 ctt ctg gaa gct cac gcc cgc cgc gtc gcc gcc gct gct ggc cgg cgt      336
 Leu Leu Glu Ala His Ala Arg Arg Val Ala Ala Ala Ala Gly Arg Arg
             100                 105                 110

 cac cac cag ccg cgg tcg gcc gtc ctc cgg gcg cgc ggc ggg cag agc      384
 His His Gln Pro Arg Ser Ala Val Leu Arg Ala Arg Gly Gly Gln Ser
         115                 120                 125

 agt gcc cgc ggc gtc cgc gta aac ggg ccg cag gct gac ggg cag cca      432
 Ser Ala Arg Gly Val Arg Val Asn Gly Pro Gln Ala Asp Gly Gln Pro
     130                 135                 140

 gcg cgg cga gaa gag cac gtt cca ggt gac ccg gcg gcc cgc gtc gtg      480
 Ala Arg Arg Glu Glu His Val Pro Gly Asp Pro Ala Ala Arg Val Val
 145                 150                 155                 160

 gcc act cgg gcc cag ctg cgt ctg gaa gct ggt gct gcg gtc gtc gcg      528
 Ala Thr Arg Ala Gln Leu Arg Leu Glu Ala Gly Ala Ala Val Val Ala
                 165                 170                 175

 ggc cgg gtt gtt gat gac cca cgg ggc gcc cca ggc ggg cgc gag gta      576
 Gly Arg Val Val Asp Asp Pro Arg Gly Ala Pro Gly Gly Arg Glu Val
             180                 185                 190

 gtt gcg ggg cag gaa ggc gct gcc gtt gac gtc gaa gaa ctt ggc gta      624
 Val Ala Gly Gln Glu Gly Ala Ala Val Asp Val Glu Glu Leu Gly Val
         195                 200                 205

 gtg cag cgg cga cgc ggc gtg gaa ctg gta ggc ctg cag cag gag gtc      672
 Val Gln Arg Arg Arg Gly Val Glu Leu Val Gly Leu Gln Gln Glu Val
     210                 215                 220

 ggc cac cgc ggg gcc gtg gcg cgc cag ggc tgc cga gcg cgc ctg cag      720
 Gly His Arg Gly Ala Val Ala Arg Gln Gly Cys Arg Ala Arg Leu Gln
 225                 230                 235                 240

 ctg gaa cag ctg tgc cgg tgg gat cat ggg gta gcg tat ggc gcg cag      768
 Leu Glu Gln Leu Cys Arg Trp Asp His Gly Val Ala Tyr Gly Ala Gln
                 245                 250                 255

 cgc ccg ctc ggc cac ggc agg ggg cgg ccg cgc gcg acc cag cca ggc      816
 Arg Pro Leu Gly His Gly Arg Gly Arg Pro Arg Ala Thr Gln Pro Gly
             260                 265                 270

 ctc cag cgc gtg gaa cag ctc cag ttc atc ctg cag cac cag gtc cga      864
 Leu Gln Arg Val Glu Gln Leu Gln Phe Ile Leu Gln His Gln Val Arg
         275                 280                 285

 gcg ttg cag gag ctg cca gag cag ctc ggg gct cac ggc gcc cca ctc      912
 Ala Leu Gln Glu Leu Pro Glu Gln Leu Gly Ala His Gly Ala Pro Leu
     290                 295                 300

 ggt gct ggc cgc cac ggc cga cag gtt cca ggc cag gaa ctg cag gca      960
 Gly Ala Gly Arg His Gly Arg Gln Val Pro Gly Gln Glu Leu Gln Ala
 305                 310                 315                 320

 gct ctc gcg cag ggc ctc gtc ccc ggt gcc cac cgc gta gtg gta cca     1008
 Ala Leu Ala Gln Gly Leu Val Pro Gly Ala His Arg Val Val Val Pro
                 325                 330                 335

 gcc cac cgc cgg gcc cgc gcc tcc cgc cag gtg cgc gcg cat gta gtc     1056
 Ala His Arg Arg Ala Arg Ala Ser Arg Gln Val Arg Ala His Val Val
             340                 345                 350

 ggc cac gcc gcg ctg cag gga gga cac gcc gta ctt ggt ggc cag tct     1104
 Gly His Ala Ala Leu Gln Gly Gly His Ala Val Leu Gly Gly Gln Ser
         355                 360                 365

 gtg cag ggg gat ggc ctg ggt cag cag cac ggt cag ctc ccc gca gta     1152
 Val Gln Gly Asp Gly Leu Gly Gln Gln His Gly Gln Leu Pro Ala Val
     370                 375                 380

 cag gta cct gcg gga gag acc gag agg tgg ggc ggg gtc agg gcg gta     1200
 Gln Val Pro Ala Gly Glu Thr Glu Arg Trp Gly Gly Val Arg Ala Val
 385                 390                 395                 400

 ccc acc tcc cag gat aga ttt ttt aga gtc cac agg gga ccc ggc ctg     1248
 Pro Thr Ser Gln Asp Arg Phe Phe Arg Val His Arg Gly Pro Gly Leu
                 405                 410                 415

 gag ttg gag ctt cac tgt ccg ggt gca aac aca gtg gaa gcc cca ccc     1296
 Glu Leu Glu Leu His Cys Pro Gly Ala Asn Thr Val Glu Ala Pro Pro
             420                 425                 430

 tga                                                                 1299
 






      <210> 150
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 150
  atg ctg agg agc tgc gcc gcg cgc ctc cgc acg ctg ggg gct ctg tgc      48
  Met Leu Arg Ser Cys Ala Ala Arg Leu Arg Thr Leu Gly Ala Leu Cys
    1               5                  10                  15

 ctg ccg cca gta ggc cgg cgc ctg ccg gga agc gag ccg cga ccc gag       96
 Leu Pro Pro Val Gly Arg Arg Leu Pro Gly Ser Glu Pro Arg Pro Glu
              20                  25                  30

 ctg ctc cac caa gcg gcc aat att tct ggc ttt caa act tta ctt aaa      144
 Leu Leu His Gln Ala Ala Asn Ile Ser Gly Phe Gln Thr Leu Leu Lys
          35                  40                  45

 ggc tca gag aaa gga aaa tcc aag gtg gtt ggt gga ggg cag ggg aat      192
 Gly Ser Glu Lys Gly Lys Ser Lys Val Val Gly Gly Gly Gln Gly Asn
      50                  55                  60

 cga caa ata gcg aaa ggg cat aca gat acc aaa cca gaa agg act cat      240
 Arg Gln Ile Ala Lys Gly His Thr Asp Thr Lys Pro Glu Arg Thr His
  65                  70                  75                  80

 tcc cta agc cag gat gaa tct ggg cca tgc cgg gct aaa cga agc tat      288
 Ser Leu Ser Gln Asp Glu Ser Gly Pro Cys Arg Ala Lys Arg Ser Tyr
                  85                  90                  95

 gca atg ggg tta cag gcc acg ccc cca agg acg taa                      324
 Ala Met Gly Leu Gln Ala Thr Pro Pro Arg Thr 
             100                 105





      <210> 151
      <211> 501
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(501)

      <400> 151
  atg tcc ttc act gta tcc atg gca atc ggg ctg gta ctt gga gga ttt      48
  Met Ser Phe Thr Val Ser Met Ala Ile Gly Leu Val Leu Gly Gly Phe
    1               5                  10                  15

 att tgg gct gtg ttc att tgt ctg tct cga aga aga aga gcc agt gct       96
 Ile Trp Ala Val Phe Ile Cys Leu Ser Arg Arg Arg Arg Ala Ser Ala
              20                  25                  30

 ccc atc tca cag tgg agt tca agc agg aga tct agg tct tct tac acc      144
 Pro Ile Ser Gln Trp Ser Ser Ser Arg Arg Ser Arg Ser Ser Tyr Thr
          35                  40                  45

 cac ggc ctc aac aga act gga ttt tac cgc cac agt ggc tgt gaa cgt      192
 His Gly Leu Asn Arg Thr Gly Phe Tyr Arg His Ser Gly Cys Glu Arg
      50                  55                  60

 cga agc aac ctc agc ctg gcc agt ctc acc ttc cag cga caa gct tcc      240
 Arg Ser Asn Leu Ser Leu Ala Ser Leu Thr Phe Gln Arg Gln Ala Ser
  65                  70                  75                  80

 ctg gaa caa gca aat tcc ttt cca aga aaa tca agt ttc aga gct tct      288
 Leu Glu Gln Ala Asn Ser Phe Pro Arg Lys Ser Ser Phe Arg Ala Ser
                  85                  90                  95

 act ttc cat ccc ttt ctg caa tgt cca cca ctt cct gtg gaa act gag      336
 Thr Phe His Pro Phe Leu Gln Cys Pro Pro Leu Pro Val Glu Thr Glu
             100                 105                 110

 agt cag ctg gtg act ctc cct tct tcc aat atc tct ccc acc atc agc      384
 Ser Gln Leu Val Thr Leu Pro Ser Ser Asn Ile Ser Pro Thr Ile Ser
         115                 120                 125

 act tcc cac agt ctg agc cgt cct gac tac tgg tcc agt aac agt ctt      432
 Thr Ser His Ser Leu Ser Arg Pro Asp Tyr Trp Ser Ser Asn Ser Leu
     130                 135                 140

 cga gtg ggc ctt tca aca ccg ccc cca cct gcc tat gag tcc atc atc      480
 Arg Val Gly Leu Ser Thr Pro Pro Pro Pro Ala Tyr Glu Ser Ile Ile
 145                 150                 155                 160

 aag gca ttc cca gat tcc tga                                          501
 Lys Ala Phe Pro Asp Ser 
                 165





      <210> 152
      <211> 741
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(741)

      <400> 152
  atg gca gca gcc gcc atc cca gct ttg ctt ctg tgc ctc ccg ctt ctg      48
  Met Ala Ala Ala Ala Ile Pro Ala Leu Leu Leu Cys Leu Pro Leu Leu
    1               5                  10                  15

 ttc ctg ctg ttc ggc tgg tcc cgg gct agg cga gac gac cct cac tct       96
 Phe Leu Leu Phe Gly Trp Ser Arg Ala Arg Arg Asp Asp Pro His Ser
              20                  25                  30

 ctt tgc tat gac atc acc gtc atc cct aag ttc aga cct gga cca cgg      144
 Leu Cys Tyr Asp Ile Thr Val Ile Pro Lys Phe Arg Pro Gly Pro Arg
          35                  40                  45

 tgg tgt gcg gtt caa ggc cag gtg gat gaa aag act ttt ctt cac tat      192
 Trp Cys Ala Val Gln Gly Gln Val Asp Glu Lys Thr Phe Leu His Tyr
      50                  55                  60

 gac tgt ggc aac aag aca gtc aca ccc gtc agt ccc ctg ggg aag aaa      240
 Asp Cys Gly Asn Lys Thr Val Thr Pro Val Ser Pro Leu Gly Lys Lys
  65                  70                  75                  80

 cta aat gtc aca atg gcc tgg aaa gca cag aac cca gta ctg aga gag      288
 Leu Asn Val Thr Met Ala Trp Lys Ala Gln Asn Pro Val Leu Arg Glu
                  85                  90                  95

 gtg gtg gac ata ctt aca gag caa ctg ctt gac att cag ctg gag aat      336
 Val Val Asp Ile Leu Thr Glu Gln Leu Leu Asp Ile Gln Leu Glu Asn
             100                 105                 110

 tac aca ccc aag gaa ccc ctc acc ctg cag gca agg atg tct tgt gag      384
 Tyr Thr Pro Lys Glu Pro Leu Thr Leu Gln Ala Arg Met Ser Cys Glu
         115                 120                 125

 cag aaa gct gaa gga cac agc agt gga tct tgg cag ttc agt atc gat      432
 Gln Lys Ala Glu Gly His Ser Ser Gly Ser Trp Gln Phe Ser Ile Asp
     130                 135                 140

 gga cag acc ttc cta ctc ttt gac tca gag aag aga atg tgg aca acg      480
 Gly Gln Thr Phe Leu Leu Phe Asp Ser Glu Lys Arg Met Trp Thr Thr
 145                 150                 155                 160

 gtt cat cct gga gcc aga aag atg aaa gaa aag tgg gag aat gac aag      528
 Val His Pro Gly Ala Arg Lys Met Lys Glu Lys Trp Glu Asn Asp Lys
                 165                 170                 175

 gat gtg gcc atg tcc ttc cat tac atc tca atg gga gac tgc ata gga      576
 Asp Val Ala Met Ser Phe His Tyr Ile Ser Met Gly Asp Cys Ile Gly
             180                 185                 190

 tgg ctt gag gac ttc ttg atg ggc atg gac agc acc ctg gag cca agt      624
 Trp Leu Glu Asp Phe Leu Met Gly Met Asp Ser Thr Leu Glu Pro Ser
         195                 200                 205

 gca gga gca cca ctc gcc atg tcc tca ggc aca acc caa ctc agg gcc      672
 Ala Gly Ala Pro Leu Ala Met Ser Ser Gly Thr Thr Gln Leu Arg Ala
     210                 215                 220

 aca gcc acc acc ctc atc ctt tgc tgc ctc ctc atc atc ctc ccc tgc      720
 Thr Ala Thr Thr Leu Ile Leu Cys Cys Leu Leu Ile Ile Leu Pro Cys
 225                 230                 235                 240

 ttc atc ctc cct ggc atc tga                                          741
 Phe Ile Leu Pro Gly Ile 
                 245





      <210> 153
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 153
  atg aac ttg aag aaa ctg ctg ctg ctg caa acc aat ggg ctt tgg gga      48
  Met Asn Leu Lys Lys Leu Leu Leu Leu Gln Thr Asn Gly Leu Trp Gly
    1               5                  10                  15

 act gtg ctt ccc ttc aga aag gaa aga gta ttt aac gat gaa aag gaa       96
 Thr Val Leu Pro Phe Arg Lys Glu Arg Val Phe Asn Asp Glu Lys Glu
              20                  25                  30

 gtg tcc ctt aac gga gag gat gac tat gtc act gaa gaa gtg gag ggg      144
 Val Ser Leu Asn Gly Glu Asp Asp Tyr Val Thr Glu Glu Val Glu Gly
          35                  40                  45

 ctg aaa atg gac tca gct ctt ggc ccc tgt aga gac tgc aag act ccg      192
 Leu Lys Met Asp Ser Ala Leu Gly Pro Cys Arg Asp Cys Lys Thr Pro
      50                  55                  60

 tgc aca acg tga                                                      204
 Cys Thr Thr 
  65





      <210> 154
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 154
  atg aag ccg cgg acc ctc acg gtg tta cag ttc tta atg atg gtg tgg      48
  Met Lys Pro Arg Thr Leu Thr Val Leu Gln Phe Leu Met Met Val Trp
    1               5                  10                  15

 ctg ggg ttt gtt cct tct gtt gtt cag acg tat cca gag ttt cct ccc       96
 Leu Gly Phe Val Pro Ser Val Val Gln Thr Tyr Pro Glu Phe Pro Pro
              20                  25                  30

 tct ggt ggg ttc acg gtc tcg ctg act cca gga gtg aat ctg cag atc      144
 Ser Gly Gly Phe Thr Val Ser Leu Thr Pro Gly Val Asn Leu Gln Ile
          35                  40                  45

 ttc act atg att gtt aca gtt cat aaa agc aat gca tcc gga gtt gtt      192
 Phe Thr Met Ile Val Thr Val His Lys Ser Asn Ala Ser Gly Val Val
      50                  55                  60

 tgt tcc tcc tgg tgg gtt cct ggt ctt gct gac ttc agg agt gaa gct      240
 Cys Ser Ser Trp Trp Val Pro Gly Leu Ala Asp Phe Arg Ser Glu Ala
  65                  70                  75                  80

 gca gac ctt ctt gtc aaa gga ttt aaa gaa gct att aat cag tat gga      288
 Ala Asp Leu Leu Val Lys Gly Phe Lys Glu Ala Ile Asn Gln Tyr Gly
                  85                  90                  95

 cca ggt tct cct ttt gta atg gga ctg tta aag aat gtt gct gtt tcc      336
 Pro Gly Ser Pro Phe Val Met Gly Leu Leu Lys Asn Val Ala Val Ser
             100                 105                 110

 agt cgg atg att cct act gac tgg gat gct ctt act cga gct tgt cta      384
 Ser Arg Met Ile Pro Thr Asp Trp Asp Ala Leu Thr Arg Ala Cys Leu
         115                 120                 125

 act cct gct cag ttc tta caa ttt aaa act tgg tgg gca gat gaa gct      432
 Thr Pro Ala Gln Phe Leu Gln Phe Lys Thr Trp Trp Ala Asp Glu Ala
     130                 135                 140

 tcc att cag gct gct tgc aac gcc cag gcc caa cct caa att aat ata      480
 Ser Ile Gln Ala Ala Cys Asn Ala Gln Ala Gln Pro Gln Ile Asn Ile
 145                 150                 155                 160

 act gca gac caa ctt ttg ggg att ggc agc tgg gct ggt tga              522
 Thr Ala Asp Gln Leu Leu Gly Ile Gly Ser Trp Ala Gly 
                 165                 170





      <210> 155
      <211> 621
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(621)

      <400> 155
  atg ccc aca cct gaa tcc cta gaa cta ctg ccc atg tta ctc cac atg      48
  Met Pro Thr Pro Glu Ser Leu Glu Leu Leu Pro Met Leu Leu His Met
    1               5                  10                  15

 gca aat ggg act ctg tgg ctc tgc tta cag atc tta aga tgt gga gat       96
 Ala Asn Gly Thr Leu Trp Leu Cys Leu Gln Ile Leu Arg Cys Gly Asp
              20                  25                  30

 gat cct gga tca cct ggt gga gcc agt gtc atc aca aga gtc ctt tta      144
 Asp Pro Gly Ser Pro Gly Gly Ala Ser Val Ile Thr Arg Val Leu Leu
          35                  40                  45

 agt gag aga gag gca gga aag tcg gag tct gag aac ggg aga tca gag      192
 Ser Glu Arg Glu Ala Gly Lys Ser Glu Ser Glu Asn Gly Arg Ser Glu
      50                  55                  60

 aac aga agc aga gga ttc aac ctg gaa gaa cta agg agt cca cag agg      240
 Asn Arg Ser Arg Gly Phe Asn Leu Glu Glu Leu Arg Ser Pro Gln Arg
  65                  70                  75                  80

 ttc tac caa agt gaa ctt gcc agc ctc gct tat cac tct gcc aat gac      288
 Phe Tyr Gln Ser Glu Leu Ala Ser Leu Ala Tyr His Ser Ala Asn Asp
                  85                  90                  95

 act cat gcc tct tcc ctg cct cac ctg caa aag ctg gtt gtg caa acc      336
 Thr His Ala Ser Ser Leu Pro His Leu Gln Lys Leu Val Val Gln Thr
             100                 105                 110

 cga act gtg gaa gag atc atc tta ttc ccc caa ctc agc atc cct ttg      384
 Arg Thr Val Glu Glu Ile Ile Leu Phe Pro Gln Leu Ser Ile Pro Leu
         115                 120                 125

 cag ttc cac agt tgc ccc atg act gac ttc acc aag cca ggc ttt gct      432
 Gln Phe His Ser Cys Pro Met Thr Asp Phe Thr Lys Pro Gly Phe Ala
     130                 135                 140

 gca atg cta agg gtc tca gaa ctg ggc aga gat ggc tca cac aca gct      480
 Ala Met Leu Arg Val Ser Glu Leu Gly Arg Asp Gly Ser His Thr Ala
 145                 150                 155                 160

 cgt ggc cgc atc cat ccc aag ggt gtt agt gag gaa gcc aac cta ctc      528
 Arg Gly Arg Ile His Pro Lys Gly Val Ser Glu Glu Ala Asn Leu Leu
                 165                 170                 175

 agg gca ttg ttc gtg atg cag cct aac tta gca aga ctt aca gaa tat      576
 Arg Ala Leu Phe Val Met Gln Pro Asn Leu Ala Arg Leu Thr Glu Tyr
             180                 185                 190

 cct gtc ata tct agc cct gcc tat gtc ttt gag ttc atc tct tga          621
 Pro Val Ile Ser Ser Pro Ala Tyr Val Phe Glu Phe Ile Ser 
         195                 200                 205





      <210> 156
      <211> 216
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(216)

      <400> 156
  atg aag gtt tct gca gcg ctt ctg tgc ctg ctg ctc atg gca gcc act      48
  Met Lys Val Ser Ala Ala Leu Leu Cys Leu Leu Leu Met Ala Ala Thr
    1               5                  10                  15

 ttc agc cct cag gga ctt gct cag cca gtt ttg gga gga gac agt gga       96
 Phe Ser Pro Gln Gly Leu Ala Gln Pro Val Leu Gly Gly Asp Ser Gly
              20                  25                  30

 gcc gct aca gca aca acc ctc cca ttg ttt ggg gaa ata atc cag aac      144
 Ala Ala Thr Ala Thr Thr Leu Pro Leu Phe Gly Glu Ile Ile Gln Asn
          35                  40                  45

 gaa gaa ctg ttt ctc act gtg ggt gta aag gac att tca ggc cgt agt      192
 Glu Glu Leu Phe Leu Thr Val Gly Val Lys Asp Ile Ser Gly Arg Ser
      50                  55                  60

 gga gag gga gaa act att gcc tga                                      216
 Gly Glu Gly Glu Thr Ile Ala 
  65                  70





      <210> 157
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 157
  atg atg cgg acg cag tgt ctg ctg ggg ctg cgc acg ttc gtg gcc ttc      48
  Met Met Arg Thr Gln Cys Leu Leu Gly Leu Arg Thr Phe Val Ala Phe
    1               5                  10                  15

 gcc gcc aag ctc tgg agc ttc ttc att tac ctt ttg cgg agg cag atc       96
 Ala Ala Lys Leu Trp Ser Phe Phe Ile Tyr Leu Leu Arg Arg Gln Ile
              20                  25                  30

 cgc acg cat atg caa ccc gag ata gca agg ctg gac act gga gct ctt      144
 Arg Thr His Met Gln Pro Glu Ile Ala Arg Leu Asp Thr Gly Ala Leu
          35                  40                  45

 tcg gac ctc atc atg gcc cag gga gaa aag aag ggc aga tct tga          189
 Ser Asp Leu Ile Met Ala Gln Gly Glu Lys Lys Gly Arg Ser 
      50                  55                  60





      <210> 158
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 158
  atg ctg gtg gtg gcc ttt ggg ctg ctg gtg ctc tac atc ctt ctg gct      48
  Met Leu Val Val Ala Phe Gly Leu Leu Val Leu Tyr Ile Leu Leu Ala
    1               5                  10                  15

 tca tct tgg aag cgc cca gag ccg ggg atc ctg acc gac aga cag ggc       96
 Ser Ser Trp Lys Arg Pro Glu Pro Gly Ile Leu Thr Asp Arg Gln Gly
              20                  25                  30

 ccc agc ccc tct gac cac tct gca gct cac cat gca gct gat gcc aaa      144
 Pro Ser Pro Ser Asp His Ser Ala Ala His His Ala Ala Asp Ala Lys
          35                  40                  45

 gtt gtg gtg tcc agt gtg cag cag ccc tgg gag cca ctg cca cct tca      192
 Val Val Val Ser Ser Val Gln Gln Pro Trp Glu Pro Leu Pro Pro Ser
      50                  55                  60

 gag ggg ttc ctt gct gag acc cac att gct tca cct ggc ccc acc atg      240
 Glu Gly Phe Leu Ala Glu Thr His Ile Ala Ser Pro Gly Pro Thr Met
  65                  70                  75                  80

 gct gct tgc ctg gcc caa cct agc gtt ctg tgc cat gct aga gct tga      288
 Ala Ala Cys Leu Ala Gln Pro Ser Val Leu Cys His Ala Arg Ala 
                  85                  90                  95





      <210> 159
      <211> 372
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(372)

      <400> 159
  atg gcc atc att aca gta aat tgc aag gct ctc atg atg act ata gag      48
  Met Ala Ile Ile Thr Val Asn Cys Lys Ala Leu Met Met Thr Ile Glu
    1               5                  10                  15

 agg cag att gat ttg ttc ctt ctg att gtc act gtg ctg aac gtg gcc       96
 Arg Gln Ile Asp Leu Phe Leu Leu Ile Val Thr Val Leu Asn Val Ala
              20                  25                  30

 gga gtg atg ggc acc cag att tca cac ctt gta atg gcc ctg cca ggg      144
 Gly Val Met Gly Thr Gln Ile Ser His Leu Val Met Ala Leu Pro Gly
          35                  40                  45

 tgg atg tta gca caa ttg gga cct gac gct tca ata aat ctg aga cat      192
 Trp Met Leu Ala Gln Leu Gly Pro Asp Ala Ser Ile Asn Leu Arg His
      50                  55                  60

 tct gct gtg gag atc aaa gtt cgg aat tgc tta aat tgg tgt tgg agc      240
 Ser Ala Val Glu Ile Lys Val Arg Asn Cys Leu Asn Trp Cys Trp Ser
  65                  70                  75                  80

 agg ttg gta tca atg ggt tat cag ttt tca cgt gag tgt gga cga caa      288
 Arg Leu Val Ser Met Gly Tyr Gln Phe Ser Arg Glu Cys Gly Arg Gln
                  85                  90                  95

 ttt cat ctc cta cct gca tat gct gct aac tcc cca agc tac act tcc      336
 Phe His Leu Leu Pro Ala Tyr Ala Ala Asn Ser Pro Ser Tyr Thr Ser
             100                 105                 110

 agc cat gac ctc tca tct tca ctt cag act cat tag                      372
 Ser His Asp Leu Ser Ser Ser Leu Gln Thr His 
         115                 120





      <210> 160
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 160
  atg gtg cac atc agc cgg ctt cct ggt gga ttc ctc atc ctg cag gag      48
  Met Val His Ile Ser Arg Leu Pro Gly Gly Phe Leu Ile Leu Gln Glu
    1               5                  10                  15

 gta cgg aaa aaa gga aaa ctc aag cat tct act gga aaa ctg gag cta       96
 Val Arg Lys Lys Gly Lys Leu Lys His Ser Thr Gly Lys Leu Glu Leu
              20                  25                  30

 aaa gca gcc cat cca tgg aga att atg gga cca gaa gat gag gca gca      144
 Lys Ala Ala His Pro Trp Arg Ile Met Gly Pro Glu Asp Glu Ala Ala
          35                  40                  45

 cag tcg gtg gat tct atc acc aac cag acg agc ctc ctg att cct gtt      192
 Gln Ser Val Asp Ser Ile Thr Asn Gln Thr Ser Leu Leu Ile Pro Val
      50                  55                  60

 cct cct cag tgg ccg ctg act cac ata gat gga gcc tcc gac tgt ctt      240
 Pro Pro Gln Trp Pro Leu Thr His Ile Asp Gly Ala Ser Asp Cys Leu
  65                  70                  75                  80

 ggt ttg gtc ccc ccc atg cca aga aag tga                              270
 Gly Leu Val Pro Pro Met Pro Arg Lys 
                  85





      <210> 161
      <211> 300
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(300)

      <400> 161
  atg ccc ttt gtg atg tcc tcc aat aca tta acc ctt atg gca ttt atg      48
  Met Pro Phe Val Met Ser Ser Asn Thr Leu Thr Leu Met Ala Phe Met
    1               5                  10                  15

 cca ctt agc cta agc ttg aac tgg aga gct acc tcc att cca gat ccc       96
 Pro Leu Ser Leu Ser Leu Asn Trp Arg Ala Thr Ser Ile Pro Asp Pro
              20                  25                  30

 cga acg cta cag aaa agc cat aaa agc aag ctt cat cac aga tat gac      144
 Arg Thr Leu Gln Lys Ser His Lys Ser Lys Leu His His Arg Tyr Asp
          35                  40                  45

 ccc act cca tgg gaa tca tac cat agt atg aaa aat ttt aga cag gac      192
 Pro Thr Pro Trp Glu Ser Tyr His Ser Met Lys Asn Phe Arg Gln Asp
      50                  55                  60

 cta gta cac tca agg ttc ctg cca att gct aac gaa gct gaa gtc tcc      240
 Leu Val His Ser Arg Phe Leu Pro Ile Ala Asn Glu Ala Glu Val Ser
  65                  70                  75                  80

 cta tca gta aaa gaa ata aat att gga tac caa gag cct cag aga ctt      288
 Leu Ser Val Lys Glu Ile Asn Ile Gly Tyr Gln Glu Pro Gln Arg Leu
                  85                  90                  95

 ata ctg agt tga                                                      300
 Ile Leu Ser 






      <210> 162
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 162
  atg tca cct tgt atc agc ttt gct act gca ttt agc ttt gtc att tac      48
  Met Ser Pro Cys Ile Ser Phe Ala Thr Ala Phe Ser Phe Val Ile Tyr
    1               5                  10                  15

 tat ctt ctt ggt tcc tcg tca tta att cat gga tac gcc tac ttg ata       96
 Tyr Leu Leu Gly Ser Ser Ser Leu Ile His Gly Tyr Ala Tyr Leu Ile
              20                  25                  30

 gtc ttt aag gat gac tgc tcc aag atc tgc agg cag gcc ctg aag ttt      144
 Val Phe Lys Asp Asp Cys Ser Lys Ile Cys Arg Gln Ala Leu Lys Phe
          35                  40                  45

 ctg atg cag atc tgg gcc cag ccc ctc atc aac ctg cag atg gca aac      192
 Leu Met Gln Ile Trp Ala Gln Pro Leu Ile Asn Leu Gln Met Ala Asn
      50                  55                  60

 gca tct ctg tac gag cat gtg gag cgg atg cac ctc atc ggg aag agc      240
 Ala Ser Leu Tyr Glu His Val Glu Arg Met His Leu Ile Gly Lys Ser
  65                  70                  75                  80

 tgg gag cag cta aag ctc ctg ggg gat tac ctg ggc ccg tgc tgg agc      288
 Trp Glu Gln Leu Lys Leu Leu Gly Asp Tyr Leu Gly Pro Cys Trp Ser
                  85                  90                  95

 ggt gcc ctg aag gag ctc agg agg agg gct ggc cta gac agt gcc tct      336
 Gly Ala Leu Lys Glu Leu Arg Arg Arg Ala Gly Leu Asp Ser Ala Ser
             100                 105                 110

 ctg aag act gcc tcc tcc atc ctg gct gca gtg ctc cca gag ccg ggc      384
 Leu Lys Thr Ala Ser Ser Ile Leu Ala Ala Val Leu Pro Glu Pro Gly
         115                 120                 125

 ttc ctg ggg gcc agg tac aac tta ctc ttg gaa atg atc aaa gca aac      432
 Phe Leu Gly Ala Arg Tyr Asn Leu Leu Leu Glu Met Ile Lys Ala Asn
     130                 135                 140

 tat att acc cta ggg aca aac cca ttg tga                              462
 Tyr Ile Thr Leu Gly Thr Asn Pro Leu 
 145                 150





      <210> 163
      <211> 159
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(159)

      <400> 163
  atg gct cgt tct cga tgg tcg ctc tct tcg gag ctg ctg ggc ttt ttt      48
  Met Ala Arg Ser Arg Trp Ser Leu Ser Ser Glu Leu Leu Gly Phe Phe
    1               5                  10                  15

 tta gct aac tgt gtc agc ttc ttt aat tgt gcc cat gtc ggc ggc tcc       96
 Leu Ala Asn Cys Val Ser Phe Phe Asn Cys Ala His Val Gly Gly Ser
              20                  25                  30

 gcc ttc ttg gtg gat ggc aac ttc atc tgt tct tct gac atc acc att      144
 Ala Phe Leu Val Asp Gly Asn Phe Ile Cys Ser Ser Asp Ile Thr Ile
          35                  40                  45

 ctg ttc atc ttg tga                                                  159
 Leu Phe Ile Leu 
      50





      <210> 164
      <211> 258
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(258)

      <400> 164
  atg cct ctg gat ctg ctc ttg tcc atg cag cct cca gct gtg ttc ttg      48
  Met Pro Leu Asp Leu Leu Leu Ser Met Gln Pro Pro Ala Val Phe Leu
    1               5                  10                  15

 ctg gtt cct ggc att gac ccc aca aaa ccc tat gcc agt ccc tta ggg       96
 Leu Val Pro Gly Ile Asp Pro Thr Lys Pro Tyr Ala Ser Pro Leu Gly
              20                  25                  30

 aag ctg aaa act cgc cag ccg tct gag ctg gca agg gca gcc agc cca      144
 Lys Leu Lys Thr Arg Gln Pro Ser Glu Leu Ala Arg Ala Ala Ser Pro
          35                  40                  45

 cag ctg tca agc cag gaa ccc agt gtt gcc tca acg gcc tgg gca gca      192
 Gln Leu Ser Ser Gln Glu Pro Ser Val Ala Ser Thr Ala Trp Ala Ala
      50                  55                  60

 ggg ggt cta ggc cgc ccc ctc atc ctc aca tca act aga gca gag gct      240
 Gly Gly Leu Gly Arg Pro Leu Ile Leu Thr Ser Thr Arg Ala Glu Ala
  65                  70                  75                  80

 gcc tcc ttt gat gtg tga                                              258
 Ala Ser Phe Asp Val 
                  85





      <210> 165
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 165
  atg ccc ctc ccc ctg gaa cct tta ggg tgc gtt cag ctt ctc gtc ctt      48
  Met Pro Leu Pro Leu Glu Pro Leu Gly Cys Val Gln Leu Leu Val Leu
    1               5                  10                  15

 cag gtc tcg acc tcc gac cac acc aag cga tgt cct cct cct acc ctt       96
 Gln Val Ser Thr Ser Asp His Thr Lys Arg Cys Pro Pro Pro Thr Leu
              20                  25                  30

 cca agc gcg acg act cac atc cgc cgt cta ggg aca cac tca tcg ctg      144
 Pro Ser Ala Thr Thr His Ile Arg Arg Leu Gly Thr His Ser Ser Leu
          35                  40                  45

 cct ccc tca ggc acc gac ccc gaa cga gaa tgc aac aga agt aat aac      192
 Pro Pro Ser Gly Thr Asp Pro Glu Arg Glu Cys Asn Arg Ser Asn Asn
      50                  55                  60

 atc act tct gag atg agg cta caa gga caa aac gat gcc tgc ctt ggt      240
 Ile Thr Ser Glu Met Arg Leu Gln Gly Gln Asn Asp Ala Cys Leu Gly
  65                  70                  75                  80

 cac cct tct cct gct ctt tcc att gct ccc tct gat gga agc cag ttg      288
 His Pro Ser Pro Ala Leu Ser Ile Ala Pro Ser Asp Gly Ser Gln Leu
                  85                  90                  95

 cca tgt gat gag gtg ccc tat gga gag gcc cac gtg aca agg tat tgt      336
 Pro Cys Asp Glu Val Pro Tyr Gly Glu Ala His Val Thr Arg Tyr Cys
             100                 105                 110

 aaa agc cct ctg acc aat agt cat cta gaa aca gag gcc cag tac aac      384
 Lys Ser Pro Leu Thr Asn Ser His Leu Glu Thr Glu Ala Gln Tyr Asn
         115                 120                 125

 agc ctg tga                                                          393
 Ser Leu 
     130





      <210> 166
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 166
  atg atg gtg ata aca ttt act gag tac tta ctg tgt aca tgt gct gag      48
  Met Met Val Ile Thr Phe Thr Glu Tyr Leu Leu Cys Thr Cys Ala Glu
    1               5                  10                  15

 tgt tat tta gtc ctc ata gga aca atg aca ggt gaa gaa gac ctc agt       96
 Cys Tyr Leu Val Leu Ile Gly Thr Met Thr Gly Glu Glu Asp Leu Ser
              20                  25                  30

 gtg gaa gag gac gag gaa gta ctg act ttg ttg tat gac cct tgt ctg      144
 Val Glu Glu Asp Glu Glu Val Leu Thr Leu Leu Tyr Asp Pro Cys Leu
          35                  40                  45

 aac tgt tac ttt gac ccc caa aca ggg aaa tac tat gag ttg gta taa      192
 Asn Cys Tyr Phe Asp Pro Gln Thr Gly Lys Tyr Tyr Glu Leu Val 
      50                  55                  60





      <210> 167
      <211> 939
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(939)

      <400> 167
  atg gcg ctc agg ctt gta atc cca gca ctt tgg gag gct gag ctg gtg      48
  Met Ala Leu Arg Leu Val Ile Pro Ala Leu Trp Glu Ala Glu Leu Val
    1               5                  10                  15

 ggg gca ctg atg ctg gcc gcc ctc tcc cac ctg cac cga ttt ctg ctc       96
 Gly Ala Leu Met Leu Ala Ala Leu Ser His Leu His Arg Phe Leu Leu
              20                  25                  30

 tct atg tgg gtt cta cca cct ggc acc ttc aca gac gcc ttc ccc ggg      144
 Ser Met Trp Val Leu Pro Pro Gly Thr Phe Thr Asp Ala Phe Pro Gly
          35                  40                  45

 ctg ctg ttt cat ttt ccc aga aga agc caa aaa gac tgc ctc ctt ggc      192
 Leu Leu Phe His Phe Pro Arg Arg Ser Gln Lys Asp Cys Leu Leu Gly
      50                  55                  60

 ctt tcc aag tct gac cag cgg gcc atg gct tgt tac ttt ggg atc ctt      240
 Leu Ser Lys Ser Asp Gln Arg Ala Met Ala Cys Tyr Phe Gly Ile Leu
  65                  70                  75                  80

 tta ata gtc tct gcc aca ctg tgt ttt gga atg aat tac tac ttg gat      288
 Leu Ile Val Ser Ala Thr Leu Cys Phe Gly Met Asn Tyr Tyr Leu Asp
                  85                  90                  95

 gaa ttt gca aat ctg tta gac gaa ctt ctg atg aag att aat ggt ttg      336
 Glu Phe Ala Asn Leu Leu Asp Glu Leu Leu Met Lys Ile Asn Gly Leu
             100                 105                 110

 tcc gac agc cta caa ctc ccc ctt ctg gaa aaa aca tcc aac aac aca      384
 Ser Asp Ser Leu Gln Leu Pro Leu Leu Glu Lys Thr Ser Asn Asn Thr
         115                 120                 125

 ggg gag gca agg aca gaa gag agt ccc tta gtg gac att tct agt tac      432
 Gly Glu Ala Arg Thr Glu Glu Ser Pro Leu Val Asp Ile Ser Ser Tyr
     130                 135                 140

 caa gct gct gag atg gtg atg atg gcc agg aca ctg gcc acc tgc ctg      480
 Gln Ala Ala Glu Met Val Met Met Ala Arg Thr Leu Ala Thr Cys Leu
 145                 150                 155                 160

 cag cat gcc cag ggc ctg ggc ttt gag gct tgt ctt ccc atc ctg agt      528
 Gln His Ala Gln Gly Leu Gly Phe Glu Ala Cys Leu Pro Ile Leu Ser
                 165                 170                 175

 gct cca cat gct tta tct cac tgg acc ctc aca aca tgc ctt tgg cag      576
 Ala Pro His Ala Leu Ser His Trp Thr Leu Thr Thr Cys Leu Trp Gln
             180                 185                 190

 cta ggc ttt atg agt gcg gtt ctc atc ctc aag tac acc cgg gca ctc      624
 Leu Gly Phe Met Ser Ala Val Leu Ile Leu Lys Tyr Thr Arg Ala Leu
         195                 200                 205

 ctt gct caa ggc cag ttc tcg ggg cca ttt gtg att gac aaa gga gtg      672
 Leu Ala Gln Gly Gln Phe Ser Gly Pro Phe Val Ile Asp Lys Gly Val
     210                 215                 220

 agg ctt gag ctc atc ggt ctc ata tcc aga gtc tgg gaa gtc tct gag      720
 Arg Leu Glu Leu Ile Gly Leu Ile Ser Arg Val Trp Glu Val Ser Glu
 225                 230                 235                 240

 caa gaa aac tcg aag gag gaa gtc tat cga cat gaa gaa gga att aca      768
 Gln Glu Asn Ser Lys Glu Glu Val Tyr Arg His Glu Glu Gly Ile Thr
                 245                 250                 255

 gtc atc tca gat tta ttg ttg ggc aga cag tgg caa cag gga cac aag      816
 Val Ile Ser Asp Leu Leu Leu Gly Arg Gln Trp Gln Gln Gly His Lys
             260                 265                 270

 ggc atc tgc ctt cag ctc atg ttg ccc ttc tct cgt ggg aaa cac aga      864
 Gly Ile Cys Leu Gln Leu Met Leu Pro Phe Ser Arg Gly Lys His Arg
         275                 280                 285

 acc agc gga gcc ttt tta atg ttc agt ctt gag ctg ttc aca gtg gcc      912
 Thr Ser Gly Ala Phe Leu Met Phe Ser Leu Glu Leu Phe Thr Val Ala
     290                 295                 300

 cag ctt gtt cca att tcc ggg tcc tga                                  939
 Gln Leu Val Pro Ile Ser Gly Ser 
 305                 310





      <210> 168
      <211> 687
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(687)

      <400> 168
  atg gcg cgg ccg ccc cgg cag cac ccg ggg gtc tgg gcg tcg ctg ctc      48
  Met Ala Arg Pro Pro Arg Gln His Pro Gly Val Trp Ala Ser Leu Leu
    1               5                  10                  15

 ctg ctg cta ctg acg ggg ccc gcc gcc tgc gca gcc agc ccc gcg gac       96
 Leu Leu Leu Leu Thr Gly Pro Ala Ala Cys Ala Ala Ser Pro Ala Asp
              20                  25                  30

 gac ggt gcg ggc ccg ggg ggc cgg gga ccc cgg gga cgc gcg cgg ggg      144
 Asp Gly Ala Gly Pro Gly Gly Arg Gly Pro Arg Gly Arg Ala Arg Gly
          35                  40                  45

 gac acg ggc gcc gac gag gcg gtg ccg cgc cac gac tcc tcc tac ggc      192
 Asp Thr Gly Ala Asp Glu Ala Val Pro Arg His Asp Ser Ser Tyr Gly
      50                  55                  60

 acc ttc gcg ggg gag ttc tac gac ctg cgc tac ctg tcg gag gag gat      240
 Thr Phe Ala Gly Glu Phe Tyr Asp Leu Arg Tyr Leu Ser Glu Glu Asp
  65                  70                  75                  80

 tct acc acc atc cgg tgg gtg cta gtt gag ata tat ggc aaa cca ggc      288
 Ser Thr Thr Ile Arg Trp Val Leu Val Glu Ile Tyr Gly Lys Pro Gly
                  85                  90                  95

 tgt aat gca gag acc tgt gac tat ttc ctc agc tac cgg atg ata ggg      336
 Cys Asn Ala Glu Thr Cys Asp Tyr Phe Leu Ser Tyr Arg Met Ile Gly
             100                 105                 110

 gct gat gta gaa ttt gag ctg agt gca gac aca gat ggt tgg gta gca      384
 Ala Asp Val Glu Phe Glu Leu Ser Ala Asp Thr Asp Gly Trp Val Ala
         115                 120                 125

 gtt gga ttc tct tca gac aag aaa atg ggt ggt gat gat gtc atg gcc      432
 Val Gly Phe Ser Ser Asp Lys Lys Met Gly Gly Asp Asp Val Met Ala
     130                 135                 140

 tgc gtc cat gat gac aat ggc agg gtc cgc ata cag cac ttc tat aat      480
 Cys Val His Asp Asp Asn Gly Arg Val Arg Ile Gln His Phe Tyr Asn
 145                 150                 155                 160

 gta ggc cag tgg gca aag gag att cag aga aac cct gcc aga gat gaa      528
 Val Gly Gln Trp Ala Lys Glu Ile Gln Arg Asn Pro Ala Arg Asp Glu
                 165                 170                 175

 gaa gga gtt ttt gag aac aat cgc gtc acc tgc aga ttt aaa cgc cct      576
 Glu Gly Val Phe Glu Asn Asn Arg Val Thr Cys Arg Phe Lys Arg Pro
             180                 185                 190

 gtg aat gtt ccc aga gat gaa aca att gtt gat ctg cat ttg agt tgg      624
 Val Asn Val Pro Arg Asp Glu Thr Ile Val Asp Leu His Leu Ser Trp
         195                 200                 205

 tat tat ctg ttt gct tgg ggt cca gcc att cag ggt aag ctt aca ttt      672
 Tyr Tyr Leu Phe Ala Trp Gly Pro Ala Ile Gln Gly Lys Leu Thr Phe
     210                 215                 220

 cag cat ctg gat taa                                                  687
 Gln His Leu Asp 
 225





      <210> 169
      <211> 315
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(315)

      <400> 169
  atg tgg gta ctc gac gta cgg ttt cta gtg aat atg tat cac ttt ctt      48
  Met Trp Val Leu Asp Val Arg Phe Leu Val Asn Met Tyr His Phe Leu
    1               5                  10                  15

 acc atc ata agg tcg cag aat cct aag ctg aac aac ttg aag gtt aag       96
 Thr Ile Ile Arg Ser Gln Asn Pro Lys Leu Asn Asn Leu Lys Val Lys
              20                  25                  30

 cgg aac gtt aca cca aaa atc gcc ctg ctt ccc ttc act aaa cat gaa      144
 Arg Asn Val Thr Pro Lys Ile Ala Leu Leu Pro Phe Thr Lys His Glu
          35                  40                  45

 gat ggc aaa gcc aaa gag tac ctt aga aac aat agt ctt atg ata tta      192
 Asp Gly Lys Ala Lys Glu Tyr Leu Arg Asn Asn Ser Leu Met Ile Leu
      50                  55                  60

 cag aag tta tca ccc aaa act gat gac ctt gtc ctt gtc cag aag cgt      240
 Gln Lys Leu Ser Pro Lys Thr Asp Asp Leu Val Leu Val Gln Lys Arg
  65                  70                  75                  80

 cag act cat gga aac aag ttt tgt gtg gaa ttg tta cat gac att gat      288
 Gln Thr His Gly Asn Lys Phe Cys Val Glu Leu Leu His Asp Ile Asp
                  85                  90                  95

 gca gtc tca aca gaa agc tct tgg taa                                  315
 Ala Val Ser Thr Glu Ser Ser Trp 
             100





      <210> 170
      <211> 1383
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1383)

      <400> 170
  atg cat gct gca gcc aat cag acc cct ggt agc aga gcc tgg gcc cac      48
  Met His Ala Ala Ala Asn Gln Thr Pro Gly Ser Arg Ala Trp Ala His
    1               5                  10                  15

 caa agg caa tgc gga gta cag ggc ctg ctg gtc ctc tgg tca cac cca       96
 Gln Arg Gln Cys Gly Val Gln Gly Leu Leu Val Leu Trp Ser His Pro
              20                  25                  30

 ctc atg ctg gtc tcc aca tac cct tct gtg tcc cca gaa gtc gac agt      144
 Leu Met Leu Val Ser Thr Tyr Pro Ser Val Ser Pro Glu Val Asp Ser
          35                  40                  45

 gtg ggg agt tgg agt gac cca gct gga tgt gac ccc caa gac aga atg      192
 Val Gly Ser Trp Ser Asp Pro Ala Gly Cys Asp Pro Gln Asp Arg Met
      50                  55                  60

 gtg ctg gac tcg ggg tct cag gcg tat gat cag gca ccc acc agc cca      240
 Val Leu Asp Ser Gly Ser Gln Ala Tyr Asp Gln Ala Pro Thr Ser Pro
  65                  70                  75                  80

 cct acc agt ctg ctg tcc ctg cgt cat agg ctg aag cac tca gac cga      288
 Pro Thr Ser Leu Leu Ser Leu Arg His Arg Leu Lys His Ser Asp Arg
                  85                  90                  95

 gac ggg cca cca ctg tac ccc tgg tct cag tcc ctg gcc ttg ccc gtg      336
 Asp Gly Pro Pro Leu Tyr Pro Trp Ser Gln Ser Leu Ala Leu Pro Val
             100                 105                 110

 gct ctg gca gtc ccc cca gca ctg cag ccc cag cct gag cag cag tcg      384
 Ala Leu Ala Val Pro Pro Ala Leu Gln Pro Gln Pro Glu Gln Gln Ser
         115                 120                 125

 ttc tca cag atg cac ctg ggc cac cgc ggc cac atg cgt cgc agt gag      432
 Phe Ser Gln Met His Leu Gly His Arg Gly His Met Arg Arg Ser Glu
     130                 135                 140

 agc acc tac tct gta aat agt act ggc cgg cgg ggg cgt ggc acc ctg      480
 Ser Thr Tyr Ser Val Asn Ser Thr Gly Arg Arg Gly Arg Gly Thr Leu
 145                 150                 155                 160

 gga cag cct cca cct gga cgg cga tgg aac cca ggc cca gct tcc cag      528
 Gly Gln Pro Pro Pro Gly Arg Arg Trp Asn Pro Gly Pro Ala Ser Gln
                 165                 170                 175

 gga act ggc aca gac tgc tgt gca ccc cca gac tgg gta cgg gag gct      576
 Gly Thr Gly Thr Asp Cys Cys Ala Pro Pro Asp Trp Val Arg Glu Ala
             180                 185                 190

 ccc cca atg gga ctc tca ttc tct ggg atg cag gga att cta cca gcc      624
 Pro Pro Met Gly Leu Ser Phe Ser Gly Met Gln Gly Ile Leu Pro Ala
         195                 200                 205

 ccg cgt gtg tcc cat ggt agt acc cca agc tca ggc cat caa tca ccc      672
 Pro Arg Val Ser His Gly Ser Thr Pro Ser Ser Gly His Gln Ser Pro
     210                 215                 220

 cag gag aag gga tcc cga ccc cca cca gga ccc agt gag aag cag aca      720
 Gln Glu Lys Gly Ser Arg Pro Pro Pro Gly Pro Ser Glu Lys Gln Thr
 225                 230                 235                 240

 gca cga atg ctg aag gag cac caa ggg gac aga aac acc cag acc gtg      768
 Ala Arg Met Leu Lys Glu His Gln Gly Asp Arg Asn Thr Gln Thr Val
                 245                 250                 255

 gaa gca cag agc aaa cag ctt cat gtt ctg ggg gcc tat ctg gag ctt      816
 Glu Ala Gln Ser Lys Gln Leu His Val Leu Gly Ala Tyr Leu Glu Leu
             260                 265                 270

 ctg tcc agg gcc tct gtc tgc agc cct caa cct aca tca gtc ggg cag      864
 Leu Ser Arg Ala Ser Val Cys Ser Pro Gln Pro Thr Ser Val Gly Gln
         275                 280                 285

 cag gcg acc cag ctc cgc cac atc cag ccg gtt ggt ggc cat gat gtg      912
 Gln Ala Thr Gln Leu Arg His Ile Gln Pro Val Gly Gly His Asp Val
     290                 295                 300

 ctt cag ctg ctg ccg gta gcg tgc caa gtc ctg cat aag aat gca cag      960
 Leu Gln Leu Leu Pro Val Ala Cys Gln Val Leu His Lys Asn Ala Gln
 305                 310                 315                 320

 gat gcc gtt cag gta cac ctg gtc ctt gct gaa tta act tgg cag cga     1008
 Asp Ala Val Gln Val His Leu Val Leu Ala Glu Leu Thr Trp Gln Arg
                 325                 330                 335

 ggt gtc tgt ctg gcc gcg ctt ggc gcg cgc gca gta ctc ccc gca cgt     1056
 Gly Val Cys Leu Ala Ala Leu Gly Ala Arg Ala Val Leu Pro Ala Arg
             340                 345                 350

 agc gcg cca ggt cct gga aga gct ggc gga agg aca gac gca cag cgt     1104
 Ser Ala Pro Gly Pro Gly Arg Ala Gly Gly Arg Thr Asp Ala Gln Arg
         355                 360                 365

 ggc ggc tgg tgt agc aga gca gag cag cgc agc gcg cca cag gaa cgg     1152
 Gly Gly Trp Cys Ser Arg Ala Glu Gln Arg Ser Ala Pro Gln Glu Arg
     370                 375                 380

 ctg ctt gcg gag cag cac gct gtg cag gtc tgc acc tct gac ctg tgg     1200
 Leu Leu Ala Glu Gln His Ala Val Gln Val Cys Thr Ser Asp Leu Trp
 385                 390                 395                 400

 tca gca gac agg aca gag gca ctc agt aga cag agc tca gag gac agc     1248
 Ser Ala Asp Arg Thr Glu Ala Leu Ser Arg Gln Ser Ser Glu Asp Ser
                 405                 410                 415

 act cag tcc cgg cgg aag gtt caa tgt cca gct ttg cac cca ccc cat     1296
 Thr Gln Ser Arg Arg Lys Val Gln Cys Pro Ala Leu His Pro Pro His
             420                 425                 430

 gtg acc aca agc agg ctc cat gac ctt gtg gtg gga caa gat gtg gaa     1344
 Val Thr Thr Ser Arg Leu His Asp Leu Val Val Gly Gln Asp Val Glu
         435                 440                 445

 tcg gaa ggc agt gac act gat gat cct aat cct gtg tag                 1383
 Ser Glu Gly Ser Asp Thr Asp Asp Pro Asn Pro Val 
     450                 455                 460





      <210> 171
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 171
  atg aag gtg ctt ctc ctc aca ggg ctg ggg gcc ctg ttc ttc gcc tat      48
  Met Lys Val Leu Leu Leu Thr Gly Leu Gly Ala Leu Phe Phe Ala Tyr
    1               5                  10                  15

 tat tgg gat gac aac ttc gac cca gcc agc ctc cag gga gcg cga gtg       96
 Tyr Trp Asp Asp Asn Phe Asp Pro Ala Ser Leu Gln Gly Ala Arg Val
              20                  25                  30

 ctg ctg aca ggg gcc aac gct ggt gtt ggt gag gag ctg gcc tat cac      144
 Leu Leu Thr Gly Ala Asn Ala Gly Val Gly Glu Glu Leu Ala Tyr His
          35                  40                  45

 tac gcg cgt ctg ggc tcc cac ctg gtg ctc act gcc cac act gag gct      192
 Tyr Ala Arg Leu Gly Ser His Leu Val Leu Thr Ala His Thr Glu Ala
      50                  55                  60

 ctc ctg cag aag gtg gta ggg aac tgc cgg aag ctg ggc gcc ccc aag      240
 Leu Leu Gln Lys Val Val Gly Asn Cys Arg Lys Leu Gly Ala Pro Lys
  65                  70                  75                  80

 gtc ttc tac atc gcg gcg gac atg gcc tcc cct gag gcg ccc gag agc      288
 Val Phe Tyr Ile Ala Ala Asp Met Ala Ser Pro Glu Ala Pro Glu Ser
                  85                  90                  95

 gtg gtg cag ttt gcg ctg gac aag ctg ggt gag ggg ctg ggc ctg aag      336
 Val Val Gln Phe Ala Leu Asp Lys Leu Gly Glu Gly Leu Gly Leu Lys
             100                 105                 110

 cct gga gtc cgg gac cgt ggc cta ggc ctt agg gac agg acc aga att      384
 Pro Gly Val Arg Asp Arg Gly Leu Gly Leu Arg Asp Arg Thr Arg Ile
         115                 120                 125

 ggg ctg tgg gtg tgg cca cag taa                                      408
 Gly Leu Trp Val Trp Pro Gln 
     130                 135





      <210> 172
      <211> 174
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(174)

      <400> 172
  atg ctg ttc ttg gcg ttg ctg ctc ctg cca gtt gtg gtc gcc ttc gcc      48
  Met Leu Phe Leu Ala Leu Leu Leu Leu Pro Val Val Val Ala Phe Ala
    1               5                  10                  15

 aga gct gaa gct gaa gaa gat ggg gac ctg cag tgc cta gcc acg ctg       96
 Arg Ala Glu Ala Glu Glu Asp Gly Asp Leu Gln Cys Leu Ala Thr Leu
              20                  25                  30

 aag aat ggg agg aaa att tgc ttg gat ctg caa gcc ctg ctg tac aag      144
 Lys Asn Gly Arg Lys Ile Cys Leu Asp Leu Gln Ala Leu Leu Tyr Lys
          35                  40                  45

 aaa atc att aag gaa cat ttg gag agt tag                              174
 Lys Ile Ile Lys Glu His Leu Glu Ser 
      50                  55





      <210> 173
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 173
  atg gga ctc ggc gcg cga ggt gct tgg gcc gcg ctg ctc ctg ggg acg      48
  Met Gly Leu Gly Ala Arg Gly Ala Trp Ala Ala Leu Leu Leu Gly Thr
    1               5                  10                  15

 ctg cag gtg cta gcg ctg ctg ggg gcc gcc cat gaa agc gca gcc atg       96
 Leu Gln Val Leu Ala Leu Leu Gly Ala Ala His Glu Ser Ala Ala Met
              20                  25                  30

 gcg ggc gcg cgg cag ctg cgc agc gtt aag ggc aca gct gca cgg tcg      144
 Ala Gly Ala Arg Gln Leu Arg Ser Val Lys Gly Thr Ala Ala Arg Ser
          35                  40                  45

 ccg gtg gcc ctt gtc gtc gct agt aag gtc gta aca gga tga              186
 Pro Val Ala Leu Val Val Ala Ser Lys Val Val Thr Gly 
      50                  55                  60





      <210> 174
      <211> 720
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(720)

      <400> 174
  atg act gtc atg gct ttg ctg ccg ctt tcc act ttc ccg ttt tgt ttc      48
  Met Thr Val Met Ala Leu Leu Pro Leu Ser Thr Phe Pro Phe Cys Phe
    1               5                  10                  15

 ttt tgc ttc cag tgg aat acc aag agc aga gag agc atc cag gaa cct       96
 Phe Cys Phe Gln Trp Asn Thr Lys Ser Arg Glu Ser Ile Gln Glu Pro
              20                  25                  30

 aga tct gat tac tac aat cat gaa gtt cct gat att gac ctc agt gat      144
 Arg Ser Asp Tyr Tyr Asn His Glu Val Pro Asp Ile Asp Leu Ser Asp
          35                  40                  45

 tgt gaa ttc cca cat gtc att gaa att tat gac ttt ccc caa gaa ttt      192
 Cys Glu Phe Pro His Val Ile Glu Ile Tyr Asp Phe Pro Gln Glu Phe
      50                  55                  60

 cat act gaa gac ctt cta cgg gtt ttc tgc agt tat caa aag aaa gga      240
 His Thr Glu Asp Leu Leu Arg Val Phe Cys Ser Tyr Gln Lys Lys Gly
  65                  70                  75                  80

 ttt gat att aaa tgg gtg gat gat aca cat gcc cta gga gta ttc tcc      288
 Phe Asp Ile Lys Trp Val Asp Asp Thr His Ala Leu Gly Val Phe Ser
                  85                  90                  95

 agt cca att aca gct cgt gat gcg ttg ggt att aaa cac acc atg gtg      336
 Ser Pro Ile Thr Ala Arg Asp Ala Leu Gly Ile Lys His Thr Met Val
             100                 105                 110

 aag att cgt ccc ttg tca cag gcc aca aga gca gcc aag gcc aaa gct      384
 Lys Ile Arg Pro Leu Ser Gln Ala Thr Arg Ala Ala Lys Ala Lys Ala
         115                 120                 125

 aga gct tat gct gag ttc ctc cag cca gca aag gag cgt cct gag act      432
 Arg Ala Tyr Ala Glu Phe Leu Gln Pro Ala Lys Glu Arg Pro Glu Thr
     130                 135                 140

 tca gca gcc cta gcc aga agg tta gtc atc agt gcc ctt ggg gtt cga      480
 Ser Ala Ala Leu Ala Arg Arg Leu Val Ile Ser Ala Leu Gly Val Arg
 145                 150                 155                 160

 agt aag cag agc aaa acc gaa cga gaa gca gag ctc aag aaa ctg caa      528
 Ser Lys Gln Ser Lys Thr Glu Arg Glu Ala Glu Leu Lys Lys Leu Gln
                 165                 170                 175

 gaa gcc aga ggc ttt aga cag tct cat tgc ctt agc cca caa ttc ctg      576
 Glu Ala Arg Gly Phe Arg Gln Ser His Cys Leu Ser Pro Gln Phe Leu
             180                 185                 190

 gaa tct gtg aag gca att tat tct gaa aat tcc act tac cga aaa gtg      624
 Glu Ser Val Lys Ala Ile Tyr Ser Glu Asn Ser Thr Tyr Arg Lys Val
         195                 200                 205

 cat cag cat gca gct cca ctt gaa gta ttt gtt tta aat gtc tgg cta      672
 His Gln His Ala Ala Pro Leu Glu Val Phe Val Leu Asn Val Trp Leu
     210                 215                 220

 tgc aaa gga cat ttc agt gat gca att aaa aat gat tct gtt gac taa      720
 Cys Lys Gly His Phe Ser Asp Ala Ile Lys Asn Asp Ser Val Asp 
 225                 230                 235





      <210> 175
      <211> 867
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(867)

      <400> 175
  atg ggg cca gaa tat cag act gaa aaa ccc aga ctg tgg cct gga gca      48
  Met Gly Pro Glu Tyr Gln Thr Glu Lys Pro Arg Leu Trp Pro Gly Ala
    1               5                  10                  15

 tgt ttt cag tgc ctg tct ttg ctg cct gtg ctg ttg ggt aga acc atc       96
 Cys Phe Gln Cys Leu Ser Leu Leu Pro Val Leu Leu Gly Arg Thr Ile
              20                  25                  30

 cag gcg ggc agc cag gtt atg aga ggt gaa gcc ttg ccc gtg gtg ata      144
 Gln Ala Gly Ser Gln Val Met Arg Gly Glu Ala Leu Pro Val Val Ile
          35                  40                  45

 ctg cct gca aag gcc aga gcc agg acc gac cca ggt ctg aca cca aaa      192
 Leu Pro Ala Lys Ala Arg Ala Arg Thr Asp Pro Gly Leu Thr Pro Lys
      50                  55                  60

 ccc atg ctc ttt cga ttt ggg gta aaa ttt caa aac cag aca tat gtc      240
 Pro Met Leu Phe Arg Phe Gly Val Lys Phe Gln Asn Gln Thr Tyr Val
  65                  70                  75                  80

 ttc gtg ctc cag ctg gcc aaa cct ggt gcc atg gaa aat cca gat gct      288
 Phe Val Leu Gln Leu Ala Lys Pro Gly Ala Met Glu Asn Pro Asp Ala
                  85                  90                  95

 tgc tta cct ggc agg ccg tgc tgg atc tgc tac ctg ggg cca gta caa      336
 Cys Leu Pro Gly Arg Pro Cys Trp Ile Cys Tyr Leu Gly Pro Val Gln
             100                 105                 110

 gca att gag tat tcc tat gct atc ctt gga ccc tca gtt cag gaa aga      384
 Ala Ile Glu Tyr Ser Tyr Ala Ile Leu Gly Pro Ser Val Gln Glu Arg
         115                 120                 125

 cag agg gaa gaa aga ggg aag ggg tgg gaa gag gaa gga aga aag gaa      432
 Gln Arg Glu Glu Arg Gly Lys Gly Trp Glu Glu Glu Gly Arg Lys Glu
     130                 135                 140

 gaa cgc act aat ccc tgt att aaa ggt agc tgg cac cct atg gtg ttt      480
 Glu Arg Thr Asn Pro Cys Ile Lys Gly Ser Trp His Pro Met Val Phe
 145                 150                 155                 160

 gca ttc ttg gaa act acc tgc cac gta gtg agg aag ccc agg cac cca      528
 Ala Phe Leu Glu Thr Thr Cys His Val Val Arg Lys Pro Arg His Pro
                 165                 170                 175

 gca gag aag gtt ccc tgt gat gct gct gct gct gct gct gcc tct gct      576
 Ala Glu Lys Val Pro Cys Asp Ala Ala Ala Ala Ala Ala Ala Ser Ala
             180                 185                 190

 ttg gga tcc aca gct cta aag gaa ccc aca gtg caa aca gcg aca aat      624
 Leu Gly Ser Thr Ala Leu Lys Glu Pro Thr Val Gln Thr Ala Thr Asn
         195                 200                 205

 ggc cat ttg atc ctt gac ttc agc cat gtc ctt ccg gca gtc caa agc      672
 Gly His Leu Ile Leu Asp Phe Ser His Val Leu Pro Ala Val Gln Ser
     210                 215                 220

 agc ata cca ccc agc ggc cag ccc aga gag aag ggc ttt tct gta ctg      720
 Ser Ile Pro Pro Ser Gly Gln Pro Arg Glu Lys Gly Phe Ser Val Leu
 225                 230                 235                 240

 cat ggg gct agg cga agg ctt gag cag agc aga cag gct gtt cca tct      768
 His Gly Ala Arg Arg Arg Leu Glu Gln Ser Arg Gln Ala Val Pro Ser
                 245                 250                 255

 ccc aac agg cca caa cag ttt cac tgg att cgt cca gtg gct gaa tct      816
 Pro Asn Arg Pro Gln Gln Phe His Trp Ile Arg Pro Val Ala Glu Ser
             260                 265                 270

 gca cgg tct gct cga cta ctg ctt gat gct cga ttg acg ctg atg ctg      864
 Ala Arg Ser Ala Arg Leu Leu Leu Asp Ala Arg Leu Thr Leu Met Leu
         275                 280                 285

 tag                                                                  867
 






      <210> 176
      <211> 150
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(150)

      <400> 176
  atg gcc tgt gat tcc agc aat tca aat agc tgg aaa acc ctc agc gct      48
  Met Ala Cys Asp Ser Ser Asn Ser Asn Ser Trp Lys Thr Leu Ser Ala
    1               5                  10                  15

 gca tct ctg gtc acc gga cca ccg tgg tac att tac cta tgg cca cca       96
 Ala Ser Leu Val Thr Gly Pro Pro Trp Tyr Ile Tyr Leu Trp Pro Pro
              20                  25                  30

 ggt gtc acc ctt ctc ttt act acc atg gtt tgt gaa tgg ttt tgc cag      144
 Gly Val Thr Leu Leu Phe Thr Thr Met Val Cys Glu Trp Phe Cys Gln
          35                  40                  45

 agg tga                                                              150
 Arg 






      <210> 177
      <211> 520
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(520)

      <400> 177
  atg agg aaa ctc atc gcg gga ctc att ttc ctt aaa atc tgg act tgt      48
  Met Arg Lys Leu Ile Ala Gly Leu Ile Phe Leu Lys Ile Trp Thr Cys
    1               5                  10                  15

 aca gta agg act tca act gac ctt ctt cag act gag ggc tgt tcc cag       96
 Thr Val Arg Thr Ser Thr Asp Leu Leu Gln Thr Glu Gly Cys Ser Gln
              20                  25                  30

 tat ata cat cag gtc act gag gtt ctg aaa gtc tca att att gga cag      144
 Tyr Ile His Gln Val Thr Glu Val Leu Lys Val Ser Ile Ile Gly Gln
          35                  40                  45

 tat tgc ata gct aga gaa gga aaa gga ttc act cat cct gta aga cgg      192
 Tyr Cys Ile Ala Arg Glu Gly Lys Gly Phe Thr His Pro Val Arg Arg
      50                  55                  60

 ctt agt tgt ctt agg caa aag ctg tat aat ggt acc aca aaa aca gtt      240
 Leu Ser Cys Leu Arg Gln Lys Leu Tyr Asn Gly Thr Thr Lys Thr Val
  65                  70                  75                  80

 aca tgg tgg aat tcc aat tac aca gaa aga aat cca ttc agt aaa ttt      288
 Thr Trp Trp Asn Ser Asn Tyr Thr Glu Arg Asn Pro Phe Ser Lys Phe
                  85                  90                  95

 cca aag ttg cag act gtt tgg gcc cac cca gaa ttc cac tgg gac tgg      336
 Pro Lys Leu Gln Thr Val Trp Ala His Pro Glu Phe His Trp Asp Trp
             100                 105                 110

 atg gcc ccc acc agg tta tac tgg ata tgt gga cac aga gct tat gct      384
 Met Ala Pro Thr Arg Leu Tyr Trp Ile Cys Gly His Arg Ala Tyr Ala
         115                 120                 125

 aag ctg cct gat cag tgg aca ggt agc tgt gta att agc acc att aag      432
 Lys Leu Pro Asp Gln Trp Thr Gly Ser Cys Val Ile Ser Thr Ile Lys
     130                 135                 140

 cca tct ttc ttc tta ctg ccc ata aaa aca ggt gaa ctt cta ggc ttc      480
 Pro Ser Phe Phe Leu Leu Pro Ile Lys Thr Gly Glu Leu Leu Gly Phe
 145                 150                 155                 160

 cca gtc tat gct tcc cac gaa aaa cga agc ata gcc ata g                520
 Pro Val Tyr Ala Ser His Glu Lys Arg Ser Ile Ala Ile 
                 165                 170





      <210> 178
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 178
  atg gca gtc ggc ctt gtc ttc aaa gtg gcc aga ctt tat tac aac tat      48
  Met Ala Val Gly Leu Val Phe Lys Val Ala Arg Leu Tyr Tyr Asn Tyr
    1               5                  10                  15

 ggg ttg cta ttg ttc aca gtt gct cca aag tgt ggg gtg gaa ttg aaa       96
 Gly Leu Leu Leu Phe Thr Val Ala Pro Lys Cys Gly Val Glu Leu Lys
              20                  25                  30

 ggt aag ctt ctg ctt tta tac ctg gaa atc caa gta tct caa agg ccc      144
 Gly Lys Leu Leu Leu Leu Tyr Leu Glu Ile Gln Val Ser Gln Arg Pro
          35                  40                  45

 aga gag cag aat ggt ttc ctg ggg acc ctc cat gga ccc act acc cag      192
 Arg Glu Gln Asn Gly Phe Leu Gly Thr Leu His Gly Pro Thr Thr Gln
      50                  55                  60

 atc caa ctc agg atc cac aca gtg ctc ctc aac tgc ccc atc tgt ggc      240
 Ile Gln Leu Arg Ile His Thr Val Leu Leu Asn Cys Pro Ile Cys Gly
  65                  70                  75                  80

 tca gat tgg gac cct cct gtt gag agt gga gaa cag atc ttc ttt atc      288
 Ser Asp Trp Asp Pro Pro Val Glu Ser Gly Glu Gln Ile Phe Phe Ile
                  85                  90                  95

 ttc atg taa                                                          297
 Phe Met 






      <210> 179
      <211> 549
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(549)

      <400> 179
  atg cag gtt ctg gtg aag ttc cgc ttc ctg gtt tgc agt tgg ctg tca      48
  Met Gln Val Leu Val Lys Phe Arg Phe Leu Val Cys Ser Trp Leu Ser
    1               5                  10                  15

 tct tgc tgt atc ctc cac atg ctg ggc tct gtc tgc cca gga ggg ctg       96
 Ser Cys Cys Ile Leu His Met Leu Gly Ser Val Cys Pro Gly Gly Leu
              20                  25                  30

 ctt ggc tgt gcc ttc tgt ggg tca cga gag ctc ctg gtt gga gct ctt      144
 Leu Gly Cys Ala Phe Cys Gly Ser Arg Glu Leu Leu Val Gly Ala Leu
          35                  40                  45

 ctg ctg tgg acc aag ccc tct ccc cag ctg tca cct gtg cct gca tct      192
 Leu Leu Trp Thr Lys Pro Ser Pro Gln Leu Ser Pro Val Pro Ala Ser
      50                  55                  60

 cag cgt ctg tcc tct ctt tcc cta atg ccg ccc ctc ccc caa ccc cag      240
 Gln Arg Leu Ser Ser Leu Ser Leu Met Pro Pro Leu Pro Gln Pro Gln
  65                  70                  75                  80

 cat ttg aca ccc acg tcc ata gaa acc cta cta tgg aac gtg gag aga      288
 His Leu Thr Pro Thr Ser Ile Glu Thr Leu Leu Trp Asn Val Glu Arg
                  85                  90                  95

 ccc tgg agg atg aaa cac cat gca gac aca ggg ata ggg ggt tgg aat      336
 Pro Trp Arg Met Lys His His Ala Asp Thr Gly Ile Gly Gly Trp Asn
             100                 105                 110

 ggg ggt ggc aag gag cat agg tat aga ggt gct ggg tat gtg ggg aag      384
 Gly Gly Gly Lys Glu His Arg Tyr Arg Gly Ala Gly Tyr Val Gly Lys
         115                 120                 125

 gat cca gct tgg aag tgg atc cac cag cgc cag ctg ccc cag ttg atg      432
 Asp Pro Ala Trp Lys Trp Ile His Gln Arg Gln Leu Pro Gln Leu Met
     130                 135                 140

 cca ggc ccc ctg ctg cgt gac cgt gtg aca cat agt cat tct gtg aga      480
 Pro Gly Pro Leu Leu Arg Asp Arg Val Thr His Ser His Ser Val Arg
 145                 150                 155                 160

 att gag aag gat att ggc agt ttg gga gct gtt gtt cct gct tat gta      528
 Ile Glu Lys Asp Ile Gly Ser Leu Gly Ala Val Val Pro Ala Tyr Val
                 165                 170                 175

 tgc aaa gaa cat aat tgc taa                                          549
 Cys Lys Glu His Asn Cys 
             180





      <210> 180
      <211> 1053
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1053)

      <400> 180
  atg agc ata gca gtg acc aca atg gtg gca gca gca gca tgc aag cca      48
  Met Ser Ile Ala Val Thr Thr Met Val Ala Ala Ala Ala Cys Lys Pro
    1               5                  10                  15

 tgg gtc cgg gta cca tct gcc aga caa tgt cgt cgg agc ctg gaa gcc       96
 Trp Val Arg Val Pro Ser Ala Arg Gln Cys Arg Arg Ser Leu Glu Ala
              20                  25                  30

 ccc cac gaa ctg tca gac tgg agg agc ccc ttc acc ctg ggc ctc agc      144
 Pro His Glu Leu Ser Asp Trp Arg Ser Pro Phe Thr Leu Gly Leu Ser
          35                  40                  45

 gac ctc gtc tgt aaa atg tgg gat ggc acc acg ccc aag gct gct gga      192
 Asp Leu Val Cys Lys Met Trp Asp Gly Thr Thr Pro Lys Ala Ala Gly
      50                  55                  60

 aaa gac ctg agc ttc ctc cac caa cag ctc acc ccc gtt caa gct cac      240
 Lys Asp Leu Ser Phe Leu His Gln Gln Leu Thr Pro Val Gln Ala His
  65                  70                  75                  80

 cct ctg ctg gaa aca ttg ccc cag ctg ccc tca caa cgg cct tct gaa      288
 Pro Leu Leu Glu Thr Leu Pro Gln Leu Pro Ser Gln Arg Pro Ser Glu
                  85                  90                  95

 cca gag ctt ggt att tcc aaa gac agg cgc ccg tgc aca gat tta ctt      336
 Pro Glu Leu Gly Ile Ser Lys Asp Arg Arg Pro Cys Thr Asp Leu Leu
             100                 105                 110

 tca gtg ctt cgg tgg aaa cag cac att gtg tgg gaa acg ggc tgt caa      384
 Ser Val Leu Arg Trp Lys Gln His Ile Val Trp Glu Thr Gly Cys Gln
         115                 120                 125

 act gaa aag cat ttc agg gga aga gat gtc agt aca gag ggt gac acg      432
 Thr Glu Lys His Phe Arg Gly Arg Asp Val Ser Thr Glu Gly Asp Thr
     130                 135                 140

 tac gct tgc ctt gat gtt att tta aac gtg gcc tgc tta gat cat gga      480
 Tyr Ala Cys Leu Asp Val Ile Leu Asn Val Ala Cys Leu Asp His Gly
 145                 150                 155                 160

 aaa tcg gaa cat tct cct aag tca cca tca aca caa agt gag gag cag      528
 Lys Ser Glu His Ser Pro Lys Ser Pro Ser Thr Gln Ser Glu Glu Gln
                 165                 170                 175

 acg cta cga gga aga gga cag gcc gtg gcc gac tgg ccg cct ggg gct      576
 Thr Leu Arg Gly Arg Gly Gln Ala Val Ala Asp Trp Pro Pro Gly Ala
             180                 185                 190

 ggt gcc tgc cct ggc ccc agt gcg agg ctc tgc aga ggg act atg ggc      624
 Gly Ala Cys Pro Gly Pro Ser Ala Arg Leu Cys Arg Gly Thr Met Gly
         195                 200                 205

 gtg ccc tct gca tca gag cat ctg aag cga gcc gca ttg ggt ggc aaa      672
 Val Pro Ser Ala Ser Glu His Leu Lys Arg Ala Ala Leu Gly Gly Lys
     210                 215                 220

 cgc cgc tgt gga gag gcg cac ggg ctg ctc agg agg cac ctg gct cag      720
 Arg Arg Cys Gly Glu Ala His Gly Leu Leu Arg Arg His Leu Ala Gln
 225                 230                 235                 240

 gat tct gcg gca tca ctg cag cca gag gcc tgg gga gag gag ggg gca      768
 Asp Ser Ala Ala Ser Leu Gln Pro Glu Ala Trp Gly Glu Glu Gly Ala
                 245                 250                 255

 gag atc ggt ccc tgc cag gca aac tct agt gaa aat ggc cag tgt cca      816
 Glu Ile Gly Pro Cys Gln Ala Asn Ser Ser Glu Asn Gly Gln Cys Pro
             260                 265                 270

 gca ccc cgc cag ggc cgg gaa ggg cgg ccc ttc cgg cag ctc tgg gct      864
 Ala Pro Arg Gln Gly Arg Glu Gly Arg Pro Phe Arg Gln Leu Trp Ala
         275                 280                 285

 ggc tcg ggc tgt ggg ccc acc ggc atg ctg ggc tgc ggt ccg caa gca      912
 Gly Ser Gly Cys Gly Pro Thr Gly Met Leu Gly Cys Gly Pro Gln Ala
     290                 295                 300

 tac cat ctg cta agg cca gaa gcc aca cct gtg gct tca aac caa aag      960
 Tyr His Leu Leu Arg Pro Glu Ala Thr Pro Val Ala Ser Asn Gln Lys
 305                 310                 315                 320

 gcc aaa ggg cag gac gat gga gga agg ccg gac aca ccg aag ggg tcc     1008
 Ala Lys Gly Gln Asp Asp Gly Gly Arg Pro Asp Thr Pro Lys Gly Ser
                 325                 330                 335

 aca tgc tta agc cca gac acc ctc agc cac aga tgg ggc aac tga         1053
 Thr Cys Leu Ser Pro Asp Thr Leu Ser His Arg Trp Gly Asn 
             340                 345                 350





      <210> 181
      <211> 1281
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1281)

      <400> 181
  atg gcg gcc ggc ccc att agg gtg gtg ttg gtc ctt cta ggg gtg ctc      48
  Met Ala Ala Gly Pro Ile Arg Val Val Leu Val Leu Leu Gly Val Leu
    1               5                  10                  15

 agt gtc tgt gca gcc agc ggc cat gga ctc gga gcg cat cga gtg tgc       96
 Ser Val Cys Ala Ala Ser Gly His Gly Leu Gly Ala His Arg Val Cys
              20                  25                  30

 cgc gcg ggc gcg tgc gtg gcg tcc cgg aac cgc cga gcg ctg agg gac      144
 Arg Ala Gly Ala Cys Val Ala Ser Arg Asn Arg Arg Ala Leu Arg Asp
          35                  40                  45

 tcg cgg acg cgc gcg ctg ctc ttc tac ggc aca gac ttc cgc gcg tcg      192
 Ser Arg Thr Arg Ala Leu Leu Phe Tyr Gly Thr Asp Phe Arg Ala Ser
      50                  55                  60

 gcc gcc ccg ctg ccg cgc ctg gcg cac cag agc tgg gcg ctc ctc cac      240
 Ala Ala Pro Leu Pro Arg Leu Ala His Gln Ser Trp Ala Leu Leu His
  65                  70                  75                  80

 gag gag tcg ccc ctc aac aac ttc ttg ctg agc cac ggc ccg ggc atc      288
 Glu Glu Ser Pro Leu Asn Asn Phe Leu Leu Ser His Gly Pro Gly Ile
                  85                  90                  95

 cgc ctc ttc aat ctt acc tcc acc ttc agt cgc cac tcg gat tac ccg      336
 Arg Leu Phe Asn Leu Thr Ser Thr Phe Ser Arg His Ser Asp Tyr Pro
             100                 105                 110

 ctg tcg ctg cag tgg ctg ccc ggg acc gcc tat ctg cgc cgc ccg gtg      384
 Leu Ser Leu Gln Trp Leu Pro Gly Thr Ala Tyr Leu Arg Arg Pro Val
         115                 120                 125

 cct ccg ccc atg gaa cgc gcg gag tgg cgc cgc cgc ggc tac gcg ccg      432
 Pro Pro Pro Met Glu Arg Ala Glu Trp Arg Arg Arg Gly Tyr Ala Pro
     130                 135                 140

 ctg ctc tat ctg cag tca cac tgc gac gtg cca gcg gac cgg gac cgc      480
 Leu Leu Tyr Leu Gln Ser His Cys Asp Val Pro Ala Asp Arg Asp Arg
 145                 150                 155                 160

 tac gtg cgc gag ctc atg cgc cac atc ccg gta gac tcc tac ggg aaa      528
 Tyr Val Arg Glu Leu Met Arg His Ile Pro Val Asp Ser Tyr Gly Lys
                 165                 170                 175

 tgc ctg cag aat cgg gag ctg cct acc gcg cgg cta cag gac aca gcc      576
 Cys Leu Gln Asn Arg Glu Leu Pro Thr Ala Arg Leu Gln Asp Thr Ala
             180                 185                 190

 acg gcc acc acc gag gat cca gag ctc ttg gct ttc ttg tcc cgc tat      624
 Thr Ala Thr Thr Glu Asp Pro Glu Leu Leu Ala Phe Leu Ser Arg Tyr
         195                 200                 205

 aag ttc cac ttg gcc ctg gaa aat gcc atc tgt aac gac tac atg aca      672
 Lys Phe His Leu Ala Leu Glu Asn Ala Ile Cys Asn Asp Tyr Met Thr
     210                 215                 220

 gaa aaa ctg tgg cgt ccc atg cac ctg ggc gct gtg ccc gtg tac cgc      720
 Glu Lys Leu Trp Arg Pro Met His Leu Gly Ala Val Pro Val Tyr Arg
 225                 230                 235                 240

 ggt tct ccc tct gtg agg gac tgg atg ccg aac aat cac tcc gtc atc      768
 Gly Ser Pro Ser Val Arg Asp Trp Met Pro Asn Asn His Ser Val Ile
                 245                 250                 255

 ctg att gat gat ttt gag tct cct cag aag ctg gca gag ttt att gac      816
 Leu Ile Asp Asp Phe Glu Ser Pro Gln Lys Leu Ala Glu Phe Ile Asp
             260                 265                 270

 ttt ctg gac aag aat gat gag gag tat atg aaa tac ctg gca tac aag      864
 Phe Leu Asp Lys Asn Asp Glu Glu Tyr Met Lys Tyr Leu Ala Tyr Lys
         275                 280                 285

 caa cct ggg ggc atc acc aac caa ttt ctt ctg gat agt ctg aag cat      912
 Gln Pro Gly Gly Ile Thr Asn Gln Phe Leu Leu Asp Ser Leu Lys His
     290                 295                 300

 cgg gag tgg gga gtg aat gat cct ttg ctg cct aac tac ctc aac ggc      960
 Arg Glu Trp Gly Val Asn Asp Pro Leu Leu Pro Asn Tyr Leu Asn Gly
 305                 310                 315                 320

 ttc gag tgt ttc gtc tgt gac tac gaa ctg gct cgg ctg gat gcc gag     1008
 Phe Glu Cys Phe Val Cys Asp Tyr Glu Leu Ala Arg Leu Asp Ala Glu
                 325                 330                 335

 aaa gcc cac gcg gcc tct ccc ggg gac agc ccc gtc ttt gag ccc cac     1056
 Lys Ala His Ala Ala Ser Pro Gly Asp Ser Pro Val Phe Glu Pro His
             340                 345                 350

 att gcc cag ccc tca cac atg gac tgc cca gtg ccc aca cct ggc ttt     1104
 Ile Ala Gln Pro Ser His Met Asp Cys Pro Val Pro Thr Pro Gly Phe
         355                 360                 365

 ggc aat gtg gaa gag att cct gag aat gac agt tgg aaa gag atg tgg     1152
 Gly Asn Val Glu Glu Ile Pro Glu Asn Asp Ser Trp Lys Glu Met Trp
     370                 375                 380

 ctg caa gat tat tgg caa ggt ctg gac cag ggg gaa gct ctc act gcc     1200
 Leu Gln Asp Tyr Trp Gln Gly Leu Asp Gln Gly Glu Ala Leu Thr Ala
 385                 390                 395                 400

 atg atc cac aac aat gaa aca gag cag acg aaa ttt tgg gat tac cta     1248
 Met Ile His Asn Asn Glu Thr Glu Gln Thr Lys Phe Trp Asp Tyr Leu
                 405                 410                 415

 cat gaa atc ttc atg aag agg caa cat ctc taa                         1281
 His Glu Ile Phe Met Lys Arg Gln His Leu 
             420                 425





      <210> 182
      <211> 813
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(813)

      <400> 182
  atg cgc cct gca gcc ctg cgc ggg gcc ctg ctg ggc tgc ctc tgc ctg      48
  Met Arg Pro Ala Ala Leu Arg Gly Ala Leu Leu Gly Cys Leu Cys Leu
    1               5                  10                  15

 gcg ttg ctt tgc ctg ggc ggt gcg gac aag cgc ctg cgc cct tgg ttg       96
 Ala Leu Leu Cys Leu Gly Gly Ala Asp Lys Arg Leu Arg Pro Trp Leu
              20                  25                  30

 cta tgc agt ttc tat ggc agc ggc atc ctc aga ctc aac ttt cac cct      144
 Leu Cys Ser Phe Tyr Gly Ser Gly Ile Leu Arg Leu Asn Phe His Pro
          35                  40                  45

 cgt tta gag cca att aag gta aaa tac ccg agc ggg aag cgg cag cag      192
 Arg Leu Glu Pro Ile Lys Val Lys Tyr Pro Ser Gly Lys Arg Gln Gln
      50                  55                  60

 ctc ccc aga gcc ctg gct tgg cag gga ggg gac ggc gcc cga gca gcc      240
 Leu Pro Arg Ala Leu Ala Trp Gln Gly Gly Asp Gly Ala Arg Ala Ala
  65                  70                  75                  80

 ata ttg cag ccc ccc ggg tcc ctc ctc cgg ccg gcg cag gcc ccg cgc      288
 Ile Leu Gln Pro Pro Gly Ser Leu Leu Arg Pro Ala Gln Ala Pro Arg
                  85                  90                  95

 tca cga cct cct ctg gga gcc gga tct gtc ctc tcc atc gcc gcc acc      336
 Ser Arg Pro Pro Leu Gly Ala Gly Ser Val Leu Ser Ile Ala Ala Thr
             100                 105                 110

 cgc cgg cct ctg cgt ccc ttg gct tcc gac atc ccg tct ggc cgt ccc      384
 Arg Arg Pro Leu Arg Pro Leu Ala Ser Asp Ile Pro Ser Gly Arg Pro
         115                 120                 125

 cct gtg ccg gtc cga gcc tct gtt tat ttc ctt tcc tac tat caa tac      432
 Pro Val Pro Val Arg Ala Ser Val Tyr Phe Leu Ser Tyr Tyr Gln Tyr
     130                 135                 140

 tcg acc agc aga aaa gga aag ttt aaa aat gcc aat cgc aca gtt gct      480
 Ser Thr Ser Arg Lys Gly Lys Phe Lys Asn Ala Asn Arg Thr Val Ala
 145                 150                 155                 160

 gga act atg gaa aaa gat cga ggt gga gcc tat gga aat aga gtg ctt      528
 Gly Thr Met Glu Lys Asp Arg Gly Gly Ala Tyr Gly Asn Arg Val Leu
                 165                 170                 175

 cct ata gcc cag ctg gtc atc gtc agc aca ttg gct tgt gct gaa gct      576
 Pro Ile Ala Gln Leu Val Ile Val Ser Thr Leu Ala Cys Ala Glu Ala
             180                 185                 190

 gta agg tgc tca gcc ctc acg aat gaa ggg ctt gtc cag agg gag gat      624
 Val Arg Cys Ser Ala Leu Thr Asn Glu Gly Leu Val Gln Arg Glu Asp
         195                 200                 205

 tcc gcc ctg ggc tca gaa agg atg gga gag agg ggg cca ggg gct tta      672
 Ser Ala Leu Gly Ser Glu Arg Met Gly Glu Arg Gly Pro Gly Ala Leu
     210                 215                 220

 caa ttc cag ctg gtg ctg atg gct ggc tgg tgt tct tcc gtg gag ctc      720
 Gln Phe Gln Leu Val Leu Met Ala Gly Trp Cys Ser Ser Val Glu Leu
 225                 230                 235                 240

 tcc cgt gtc tgc tgc atg gca gcc ggt gct gat ggc tgg ctg gtg ttc      768
 Ser Arg Val Cys Cys Met Ala Ala Gly Ala Asp Gly Trp Leu Val Phe
                 245                 250                 255

 ttc cgt gga gct ctc ccg tgt ctg ctg cat ggc agc cgg tgc tga          813
 Phe Arg Gly Ala Leu Pro Cys Leu Leu His Gly Ser Arg Cys 
             260                 265                 270





      <210> 183
      <211> 330
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(330)

      <400> 183
  atg ttg tat gcc ctc aac att tta aga act gta ctt gga cgt gca cgc      48
  Met Leu Tyr Ala Leu Asn Ile Leu Arg Thr Val Leu Gly Arg Ala Arg
    1               5                  10                  15

 acc ctg tcc ctc aac cac cgc tgc cgc ctc ctt ctt ctg tca ctc ctg       96
 Thr Leu Ser Leu Asn His Arg Cys Arg Leu Leu Leu Leu Ser Leu Leu
              20                  25                  30

 gtg ctg cac tgt gtt cgt tca gtg aga agc tgg tac ctc ttt tgt gaa      144
 Val Leu His Cys Val Arg Ser Val Arg Ser Trp Tyr Leu Phe Cys Glu
          35                  40                  45

 gcg gca gct gag aag act ctg gca ttt gcc atg gcc gag gaa aag ccc      192
 Ala Ala Ala Glu Lys Thr Leu Ala Phe Ala Met Ala Glu Glu Lys Pro
      50                  55                  60

 aag gca ttg tca atg ggg cag atc aga ttc cga ttt gac agt cag cca      240
 Lys Ala Leu Ser Met Gly Gln Ile Arg Phe Arg Phe Asp Ser Gln Pro
  65                  70                  75                  80

 atc aat gaa aca gac aca cct gca cag gtg gaa atg gag gat ata gat      288
 Ile Asn Glu Thr Asp Thr Pro Ala Gln Val Glu Met Glu Asp Ile Asp
                  85                  90                  95

 ata att gat gtg ttc cac cag cag ata gga ggt gtc tac tga              330
 Ile Ile Asp Val Phe His Gln Gln Ile Gly Gly Val Tyr 
             100                 105





      <210> 184
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 184
  atg ctg aag ggt ctt gtg gct cta aag ccc gtg ttc ctg tgg atg cat      48
  Met Leu Lys Gly Leu Val Ala Leu Lys Pro Val Phe Leu Trp Met His
    1               5                  10                  15

 atc aag tgt tcc tgt gga gca ctg gct tta gag cca caa gac ctg gct       96
 Ile Lys Cys Ser Cys Gly Ala Leu Ala Leu Glu Pro Gln Asp Leu Ala
              20                  25                  30

 cag tca cag atc aag gcc cca ctc acc aac ctc aca ggt cta tca ctg      144
 Gln Ser Gln Ile Lys Ala Pro Leu Thr Asn Leu Thr Gly Leu Ser Leu
          35                  40                  45

 agg cca gat gac atg cag cag gtg tgg agg ctc ctt cac aaa ccc tca      192
 Arg Pro Asp Asp Met Gln Gln Val Trp Arg Leu Leu His Lys Pro Ser
      50                  55                  60

 cac ccc tcg gta cat cct gtc ccg cat cct ctg ctc agg ctc ctc tgc      240
 His Pro Ser Val His Pro Val Pro His Pro Leu Leu Arg Leu Leu Cys
  65                  70                  75                  80

 cca aac atg caa gtc cct gat gca tcc tcc aag gct gct tct cac cct      288
 Pro Asn Met Gln Val Pro Asp Ala Ser Ser Lys Ala Ala Ser His Pro
                  85                  90                  95

 act ttc tcc cta gcc aat cac att cac tct ggc ttt gaa tgc tat ctg      336
 Thr Phe Ser Leu Ala Asn His Ile His Ser Gly Phe Glu Cys Tyr Leu
             100                 105                 110

 tca aca aat cca aat tat cct caa gat tca gtt tgc tac cta atg cac      384
 Ser Thr Asn Pro Asn Tyr Pro Gln Asp Ser Val Cys Tyr Leu Met His
         115                 120                 125

 tgt gac aaa tcc ctt ctg ctt aaa cca gct agc atg tga                  423
 Cys Asp Lys Ser Leu Leu Leu Lys Pro Ala Ser Met 
     130                 135                 140





      <210> 185
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 185
  atg gac aca ggc ttc tgt ctc caa gtt act tta ctg cct cta tgc ctc      48
  Met Asp Thr Gly Phe Cys Leu Gln Val Thr Leu Leu Pro Leu Cys Leu
    1               5                  10                  15

 ttt aga gct ggc tct cag cag agg gga gag gaa act gct cct cat gtg       96
 Phe Arg Ala Gly Ser Gln Gln Arg Gly Glu Glu Thr Ala Pro His Val
              20                  25                  30

 aaa gat aaa ccc tac aac cta tgg ata aaa cag agg caa gag ttt tgg      144
 Lys Asp Lys Pro Tyr Asn Leu Trp Ile Lys Gln Arg Gln Glu Phe Trp
          35                  40                  45

 agg tac tca gca cct ggc act gtt cct acc acc tct gct att cct ggt      192
 Arg Tyr Ser Ala Pro Gly Thr Val Pro Thr Thr Ser Ala Ile Pro Gly
      50                  55                  60

 gag act gag tgg ggc aga ctc cca cag tgg tct act gca tgg agt gaa      240
 Glu Thr Glu Trp Gly Arg Leu Pro Gln Trp Ser Thr Ala Trp Ser Glu
  65                  70                  75                  80

 aca gca caa cat ggg tgg cca gct gcc agg cag tca aga att acc gtg      288
 Thr Ala Gln His Gly Trp Pro Ala Ala Arg Gln Ser Arg Ile Thr Val
                  85                  90                  95

 cta cat cag caa ccc cag tgt gac cct gga cct gaa gta aca tct gag      336
 Leu His Gln Gln Pro Gln Cys Asp Pro Gly Pro Glu Val Thr Ser Glu
             100                 105                 110

 caa cta cca ggt gtc ata aat tgg att aga aat tgt aaa tgc ctt tgt      384
 Gln Leu Pro Gly Val Ile Asn Trp Ile Arg Asn Cys Lys Cys Leu Cys
         115                 120                 125

 gga cag ctt atc agc aca atg gga agt cct aaa tca caa tta ttg tct      432
 Gly Gln Leu Ile Ser Thr Met Gly Ser Pro Lys Ser Gln Leu Leu Ser
     130                 135                 140

 cag cgt cag tag                                                      444
 Gln Arg Gln 
 145





      <210> 186
      <211> 765
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(765)

      <400> 186
  atg gct tgt ctg atc gca tct cct acc ctc ccg ctt gtt ctc tcc agc      48
  Met Ala Cys Leu Ile Ala Ser Pro Thr Leu Pro Leu Val Leu Ser Ser
    1               5                  10                  15

 ctc atg ggc gtc ctc cac att cct ccg atg ttg ttt ctc agg aag cta       96
 Leu Met Gly Val Leu His Ile Pro Pro Met Leu Phe Leu Arg Lys Leu
              20                  25                  30

 cca gag gtt atc ctc tat cca aaa att tta aca gca tat gag atc cat      144
 Pro Glu Val Ile Leu Tyr Pro Lys Ile Leu Thr Ala Tyr Glu Ile His
          35                  40                  45

 aaa tta ata caa cca agg aaa gaa gca aaa gga att tct aga tta cgt      192
 Lys Leu Ile Gln Pro Arg Lys Glu Ala Lys Gly Ile Ser Arg Leu Arg
      50                  55                  60

 aag ggc aaa ggc aag tct aaa gaa aca agc acg aac tgg agg agg gta      240
 Lys Gly Lys Gly Lys Ser Lys Glu Thr Ser Thr Asn Trp Arg Arg Val
  65                  70                  75                  80

 aca ggc ttt ggg agg tca acc ggg gtt ggt agc agt gtt ggt tgc ctg      288
 Thr Gly Phe Gly Arg Ser Thr Gly Val Gly Ser Ser Val Gly Cys Leu
                  85                  90                  95

 ctg ctg aat gga agc tac ctg ggg tgg aac tgg gct ggt gag gca tca      336
 Leu Leu Asn Gly Ser Tyr Leu Gly Trp Asn Trp Ala Gly Glu Ala Ser
             100                 105                 110

 gga aca aag gaa gac aag cca caa ggt gct gag gga gcc gtc tcc ggc      384
 Gly Thr Lys Glu Asp Lys Pro Gln Gly Ala Glu Gly Ala Val Ser Gly
         115                 120                 125

 ctt ggc cag ccc aga aag ggg ctc cca cag tgc agc ggt ggg ctg aag      432
 Leu Gly Gln Pro Arg Lys Gly Leu Pro Gln Cys Ser Gly Gly Leu Lys
     130                 135                 140

 ggc tcc tca agc acg gcc aca gtg ggc tcc aag gcc gag gag gcg ccc      480
 Gly Ser Ser Ser Thr Ala Thr Val Gly Ser Lys Ala Glu Glu Ala Pro
 145                 150                 155                 160

 aga gtg agc cag ggc tgc gag ggc tgc cag cat gct gtc acc tct cag      528
 Arg Val Ser Gln Gly Cys Glu Gly Cys Gln His Ala Val Thr Ser Gln
                 165                 170                 175

 ctg cat ctc ttg aag agc aaa aaa act ctt gaa gct gtt ttg aca tcc      576
 Leu His Leu Leu Lys Ser Lys Lys Thr Leu Glu Ala Val Leu Thr Ser
             180                 185                 190

 ttt ctc cat cag tgt ggt agg aag agt ttt aag aca gtt ccc atg acc      624
 Phe Leu His Gln Cys Gly Arg Lys Ser Phe Lys Thr Val Pro Met Thr
         195                 200                 205

 ttc gcc ttc cgg tat tgg ggc aaa agg agg aga tta tct ggg acc cag      672
 Phe Ala Phe Arg Tyr Trp Gly Lys Arg Arg Arg Leu Ser Gly Thr Gln
     210                 215                 220

 acc agg agg ctg aac gtg gag aag tta ttt cag cag cat atc ctt cac      720
 Thr Arg Arg Leu Asn Val Glu Lys Leu Phe Gln Gln His Ile Leu His
 225                 230                 235                 240

 cca cgg ccg ttt ctg gag atc ccc aac ccc tcc atg ccc ctc tga          765
 Pro Arg Pro Phe Leu Glu Ile Pro Asn Pro Ser Met Pro Leu 
                 245                 250





      <210> 187
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 187
  atg ggc act ccc cct gag ttt cta ttt cca ctt ggc cag cct att ggt      48
  Met Gly Thr Pro Pro Glu Phe Leu Phe Pro Leu Gly Gln Pro Ile Gly
    1               5                  10                  15

 ctc tgt tgg tca tta ctg gct cga atg ctt cac agc aat ggt ttt ttc       96
 Leu Cys Trp Ser Leu Leu Ala Arg Met Leu His Ser Asn Gly Phe Phe
              20                  25                  30

 cgc ctt ctg ggg gat gac agt atc agc gtg gca agg cga tgc aag ccc      144
 Arg Leu Leu Gly Asp Asp Ser Ile Ser Val Ala Arg Arg Cys Lys Pro
          35                  40                  45

 aca agc ttt ttc caa agt ctt gag ctt ttg atg ctg tcc cgc att gtg      192
 Thr Ser Phe Phe Gln Ser Leu Glu Leu Leu Met Leu Ser Arg Ile Val
      50                  55                  60

 gac ttg tga                                                          201
 Asp Leu 
  65





      <210> 188
      <211> 402
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(402)

      <400> 188
  atg cag ctc cgc atg atg tgt gcc tca ctg ttc gcc atc acc agt ggc      48
  Met Gln Leu Arg Met Met Cys Ala Ser Leu Phe Ala Ile Thr Ser Gly
    1               5                  10                  15

 agt cag cat gac ctg cgc tgt agt ttt act gtc tgc cat ccc ttc agc       96
 Ser Gln His Asp Leu Arg Cys Ser Phe Thr Val Cys His Pro Phe Ser
              20                  25                  30

 atg gca gtc tac ttt gtg tat caa ata aaa aga aat gga atg aca gct      144
 Met Ala Val Tyr Phe Val Tyr Gln Ile Lys Arg Asn Gly Met Thr Ala
          35                  40                  45

 gag gcc cac agt gtc cat ctg tgg acc cac aac tca acc ctc ctg ggg      192
 Glu Ala His Ser Val His Leu Trp Thr His Asn Ser Thr Leu Leu Gly
      50                  55                  60

 gaa ctc ctc tat cat cct ggc tcc aag gac cac cta tgc aaa agt gaa      240
 Glu Leu Leu Tyr His Pro Gly Ser Lys Asp His Leu Cys Lys Ser Glu
  65                  70                  75                  80

 ggc aag ctg tgt aga atc aaa gct gag gtg tct agg aat ttt cag tac      288
 Gly Lys Leu Cys Arg Ile Lys Ala Glu Val Ser Arg Asn Phe Gln Tyr
                  85                  90                  95

 tat ggt gct tat gct tct ctt cta cgc ctt atg gaa gta ttt aga aag      336
 Tyr Gly Ala Tyr Ala Ser Leu Leu Arg Leu Met Glu Val Phe Arg Lys
             100                 105                 110

 gaa aaa gaa agc caa act gcg tac aca gag tgt gag gag ggt gaa gaa      384
 Glu Lys Glu Ser Gln Thr Ala Tyr Thr Glu Cys Glu Glu Gly Glu Glu
         115                 120                 125

 aac act caa gga ttt taa                                              402
 Asn Thr Gln Gly Phe 
     130





      <210> 189
      <211> 582
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(582)

      <400> 189
  atg caa aag aag cca gag gcc cac ctg ccc caa atc att cat ctc ctt      48
  Met Gln Lys Lys Pro Glu Ala His Leu Pro Gln Ile Ile His Leu Leu
    1               5                  10                  15

 gga ctg ctt ctg agt gtg aaa ctc ctg cca ttg gct tct ctt ccc tgg       96
 Gly Leu Leu Leu Ser Val Lys Leu Leu Pro Leu Ala Ser Leu Pro Trp
              20                  25                  30

 att aaa gac cag tta aaa tat gga tct gta aac tca agc ttg tgg aga      144
 Ile Lys Asp Gln Leu Lys Tyr Gly Ser Val Asn Ser Ser Leu Trp Arg
          35                  40                  45

 gag ggg atg aag cga aat tta ggg cag gaa gaa cat gag cct gct agc      192
 Glu Gly Met Lys Arg Asn Leu Gly Gln Glu Glu His Glu Pro Ala Ser
      50                  55                  60

 ata atc cac ttc tat cgc aaa gcg agc ggg tat gct cag gcc tgc ggc      240
 Ile Ile His Phe Tyr Arg Lys Ala Ser Gly Tyr Ala Gln Ala Cys Gly
  65                  70                  75                  80

 cag atg agc atg ttt gca gtg agg ccc ttc cag cac aaa cac atg gtt      288
 Gln Met Ser Met Phe Ala Val Arg Pro Phe Gln His Lys His Met Val
                  85                  90                  95

 tgg tca gtg agt cct gct tct ccc tcg gtg ctg gga gct ccc tct cac      336
 Trp Ser Val Ser Pro Ala Ser Pro Ser Val Leu Gly Ala Pro Ser His
             100                 105                 110

 acc aat gct ccc gtg gga ccc tgc tcc ctg cac cct cag agt gag ggg      384
 Thr Asn Ala Pro Val Gly Pro Cys Ser Leu His Pro Gln Ser Glu Gly
         115                 120                 125

 aac tgg agg gga gct gtc tta tac caa aac atc agc tcg tct tgg gtt      432
 Asn Trp Arg Gly Ala Val Leu Tyr Gln Asn Ile Ser Ser Ser Trp Val
     130                 135                 140

 tca agc ctg ctg gct ttt gga ctg gat ctt aca cca tca gct ctc atg      480
 Ser Ser Leu Leu Ala Phe Gly Leu Asp Leu Thr Pro Ser Ala Leu Met
 145                 150                 155                 160

 gtt ctc agc cct ttg gac tca gac tgc aac tgg aca ttg gct ctc ctg      528
 Val Leu Ser Pro Leu Asp Ser Asp Cys Asn Trp Thr Leu Ala Leu Leu
                 165                 170                 175

 ggt ctg caa ctt gca gac tgc aga tct gga ctt ttt caa cct gta att      576
 Gly Leu Gln Leu Ala Asp Cys Arg Ser Gly Leu Phe Gln Pro Val Ile
             180                 185                 190

 ctt taa                                                              582
 Leu 






      <210> 190
      <211> 570
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(570)

      <400> 190
  atg aca gtc ggg gtt ggc ttc cac ccc tta att gcg cag tgg aca gtg      48
  Met Thr Val Gly Val Gly Phe His Pro Leu Ile Ala Gln Trp Thr Val
    1               5                  10                  15

 tgc tgt caa atg gag caa cca gtg agg tct aca aga atg cct tac gga       96
 Cys Cys Gln Met Glu Gln Pro Val Arg Ser Thr Arg Met Pro Tyr Gly
              20                  25                  30

 ggc agc aaa ata gat cca ggt gga aaa gtt gca gga acc ccc ggg cca      144
 Gly Ser Lys Ile Asp Pro Gly Gly Lys Val Ala Gly Thr Pro Gly Pro
          35                  40                  45

 cac gtg agg cga gca ctc agt ctc tgc ctc gag gat gaa aga agg gcc      192
 His Val Arg Arg Ala Leu Ser Leu Cys Leu Glu Asp Glu Arg Arg Ala
      50                  55                  60

 aac tgc aca tta aaa gaa agg cca tca act tgt gat aat cct ggt cct      240
 Asn Cys Thr Leu Lys Glu Arg Pro Ser Thr Cys Asp Asn Pro Gly Pro
  65                  70                  75                  80

 tgt gtg acg gct gac gag cac aaa tgc tct caa aga agt act gtg cag      288
 Cys Val Thr Ala Asp Glu His Lys Cys Ser Gln Arg Ser Thr Val Gln
                  85                  90                  95

 cca ctg acg gtg agg gga gag gcg atc agc tgc cgg ggg cca cac tcc      336
 Pro Leu Thr Val Arg Gly Glu Ala Ile Ser Cys Arg Gly Pro His Ser
             100                 105                 110

 gaa gtg cga aca gaa tct gaa gca ccc tct cac ggg aaa tgc cgg cat      384
 Glu Val Arg Thr Glu Ser Glu Ala Pro Ser His Gly Lys Cys Arg His
         115                 120                 125

 ctc act gac ctg att ctg agc aag caa gag ggc gct gga ttg tcc cac      432
 Leu Thr Asp Leu Ile Leu Ser Lys Gln Glu Gly Ala Gly Leu Ser His
     130                 135                 140

 tct ttg aag ctc aaa atg ggc ttc tgt gcc att gtc atc atc ccc cct      480
 Ser Leu Lys Leu Lys Met Gly Phe Cys Ala Ile Val Ile Ile Pro Pro
 145                 150                 155                 160

 tta gag aca ggc gaa ttc cgc acc ccc ata aaa cga ctc act caa ggt      528
 Leu Glu Thr Gly Glu Phe Arg Thr Pro Ile Lys Arg Leu Thr Gln Gly
                 165                 170                 175

 cat tat cag ccc tac atc tat aac tca cgg act cgt gtc tag              570
 His Tyr Gln Pro Tyr Ile Tyr Asn Ser Arg Thr Arg Val 
             180                 185





      <210> 191
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 191
  atg gcg ttc aat ctg gcc ttc tgt gca cct gga gca tgg gca gct cat      48
  Met Ala Phe Asn Leu Ala Phe Cys Ala Pro Gly Ala Trp Ala Ala His
    1               5                  10                  15

 ctt ggt ctc gct gat ggc act gtt ttc cag tgg ctg aag gag cag ctc       96
 Leu Gly Leu Ala Asp Gly Thr Val Phe Gln Trp Leu Lys Glu Gln Leu
              20                  25                  30

 agc cag gct gag gca ggc gga tcc aac ccc agc gcg gtg ctt cac gga      144
 Ser Gln Ala Glu Ala Gly Gly Ser Asn Pro Ser Ala Val Leu His Gly
          35                  40                  45

 cat gtg cgc atg cgc act ggc aga gag ctg ctg cgg cac agg gac ttt      192
 His Val Arg Met Arg Thr Gly Arg Glu Leu Leu Arg His Arg Asp Phe
      50                  55                  60

 tcc tct ctg ctc ctc caa cgc ctc atc tct gcc att ggg tgg tga          237
 Ser Ser Leu Leu Leu Gln Arg Leu Ile Ser Ala Ile Gly Trp 
  65                  70                  75





      <210> 192
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 192
  atg ggc ttc tct agc cct ggc cct tcc cgc ggg acg tcc agc ctc ctc      48
  Met Gly Phe Ser Ser Pro Gly Pro Ser Arg Gly Thr Ser Ser Leu Leu
    1               5                  10                  15

 ctc tcg gcg tgg ctg att gct ctt cct cct tcg tct gtt gca cgt gga       96
 Leu Ser Ala Trp Leu Ile Ala Leu Pro Pro Ser Ser Val Ala Arg Gly
              20                  25                  30

 agg tcg gag ggc gtg gct gtg aag ctc ccg ttc ctc ctc atg gca ttg      144
 Arg Ser Glu Gly Val Ala Val Lys Leu Pro Phe Leu Leu Met Ala Leu
          35                  40                  45

 att gct gtc ccc ttc gca ccc gct gac cgc gcc ccc gcc gcg ccc gcc      192
 Ile Ala Val Pro Phe Ala Pro Ala Asp Arg Ala Pro Ala Ala Pro Ala
      50                  55                  60

 gcg ccc gcc gcc gac cag ggc tcc tgg tgc ctg tgc cag ctc aat ggg      240
 Ala Pro Ala Ala Asp Gln Gly Ser Trp Cys Leu Cys Gln Leu Asn Gly
  65                  70                  75                  80

 gcc gcc gac ctc gaa gtt tcc gaa gga cct cac cct gcc cgg gga cgc      288
 Ala Ala Asp Leu Glu Val Ser Glu Gly Pro His Pro Ala Arg Gly Arg
                  85                  90                  95

 ggc cct cgg gtg cgg gac tcc cgc gac tgg agg aga ggg cgc gtc ttc      336
 Gly Pro Arg Val Arg Asp Ser Arg Asp Trp Arg Arg Gly Arg Val Phe
             100                 105                 110

 gcg ggc cag aag cga gac tca gag agc ccg ggc acc gac ccc ggg gcg      384
 Ala Gly Gln Lys Arg Asp Ser Glu Ser Pro Gly Thr Asp Pro Gly Ala
         115                 120                 125

 gtc ctg ggg cag ggc tgg ctc tgc tag                                  411
 Val Leu Gly Gln Gly Trp Leu Cys 
     130                 135





      <210> 193
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 193
  atg gca gcg cgt tgg cgg ttt tgg tgt gtc tct gtg acc atg gtg gtg      48
  Met Ala Ala Arg Trp Arg Phe Trp Cys Val Ser Val Thr Met Val Val
    1               5                  10                  15

 gcg ctg ctc atc gtt tgc gac gtt ccc tca gcc tct gcc caa aga aag       96
 Ala Leu Leu Ile Val Cys Asp Val Pro Ser Ala Ser Ala Gln Arg Lys
              20                  25                  30

 aag gag gtg aga acg cgg ttt cca gca gca tgg gct ttt ccc aat gac      144
 Lys Glu Val Arg Thr Arg Phe Pro Ala Ala Trp Ala Phe Pro Asn Asp
          35                  40                  45

 tgg ggc tta aga ggg tct gtt cgc ctc ttc cca gcc ccc ttt ccc tgc      192
 Trp Gly Leu Arg Gly Ser Val Arg Leu Phe Pro Ala Pro Phe Pro Cys
      50                  55                  60

 cgc ttc tat gcc ttt ggt ggc ttc aat tac gcg gtt ttc gga gtt gtg      240
 Arg Phe Tyr Ala Phe Gly Gly Phe Asn Tyr Ala Val Phe Gly Val Val
  65                  70                  75                  80

 gaa ttc gtg aga gaa gga act gta act ctt tgt ctt ctg ggg atg tag      288
 Glu Phe Val Arg Glu Gly Thr Val Thr Leu Cys Leu Leu Gly Met 
                  85                  90                  95





      <210> 194
      <211> 666
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(666)

      <400> 194
  atg gct gat aat ctc tat gtg tat gct gtc ctc gtg tgc tgc gtg ggg      48
  Met Ala Asp Asn Leu Tyr Val Tyr Ala Val Leu Val Cys Cys Val Gly
    1               5                  10                  15

 atc ctc agc att ctg ctc ttc atg ctg gtc atc gtc tgg cag tct gtg       96
 Ile Leu Ser Ile Leu Leu Phe Met Leu Val Ile Val Trp Gln Ser Val
              20                  25                  30

 ttt aac aag cgg aaa tcc aga ggg cag aat gct ctg agg atg cag agc      144
 Phe Asn Lys Arg Lys Ser Arg Gly Gln Asn Ala Leu Arg Met Gln Ser
          35                  40                  45

 aga gag cag ggc ctg agt aag cgt ctc agg gat ctg tac aca ggg agc      192
 Arg Glu Gln Gly Leu Ser Lys Arg Leu Arg Asp Leu Tyr Thr Gly Ser
      50                  55                  60

 act cag aaa cta ttg gaa gct att gtg ggt ttt ttt ttt tcc ttt ctc      240
 Thr Gln Lys Leu Leu Glu Ala Ile Val Gly Phe Phe Phe Ser Phe Leu
  65                  70                  75                  80

 ttt tgc aac aaa tct gcc ttt ggt ttc act gga aac ttt ttc ttc tac      288
 Phe Cys Asn Lys Ser Ala Phe Gly Phe Thr Gly Asn Phe Phe Phe Tyr
                  85                  90                  95

 agc tca ggg gag act gtc act agc gtg acc agc ttg gcc cca cta cag      336
 Ser Ser Gly Glu Thr Val Thr Ser Val Thr Ser Leu Ala Pro Leu Gln
             100                 105                 110

 ccc aag aag ggc aag agg cag aag gag aag cct gac att cct ccc gca      384
 Pro Lys Lys Gly Lys Arg Gln Lys Glu Lys Pro Asp Ile Pro Pro Ala
         115                 120                 125

 gtc cct gcc aaa gct ccg ata gcc ccc acg ttc cat aaa ccg aag ctg      432
 Val Pro Ala Lys Ala Pro Ile Ala Pro Thr Phe His Lys Pro Lys Leu
     130                 135                 140

 ctg aaa cca cag aga aaa gtc acg ctg gta cac atg cac agc cca tta      480
 Leu Lys Pro Gln Arg Lys Val Thr Leu Val His Met His Ser Pro Leu
 145                 150                 155                 160

 ttg ttg cgg gga gtt atg tat gtc agc tgg agg gaa gaa cgg atg ctg      528
 Leu Leu Arg Gly Val Met Tyr Val Ser Trp Arg Glu Glu Arg Met Leu
                 165                 170                 175

 agg ctt cag aag gga tgg gcg tgc gga aaa cag aag cca ttt gct ttc      576
 Arg Leu Gln Lys Gly Trp Ala Cys Gly Lys Gln Lys Pro Phe Ala Phe
             180                 185                 190

 atg gct tcc tcc agt cta gag aga gca ggt atc tcg gcg ttc ggt aag      624
 Met Ala Ser Ser Ser Leu Glu Arg Ala Gly Ile Ser Ala Phe Gly Lys
         195                 200                 205

 ctg gat gtg atc aag atc ata cct ctc cca cac tgg aag tga              666
 Leu Asp Val Ile Lys Ile Ile Pro Leu Pro His Trp Lys 
     210                 215                 220





      <210> 195
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 195
  atg agg tgg gaa cca gaa cac gtg tgc cct gcc tgc aag gcc ctg cac      48
  Met Arg Trp Glu Pro Glu His Val Cys Pro Ala Cys Lys Ala Leu His
    1               5                  10                  15

 aac ctg gcc ctg ctc atc cca ctt cca gtc act ctc ttt gca cct gca       96
 Asn Leu Ala Leu Leu Ile Pro Leu Pro Val Thr Leu Phe Ala Pro Ala
              20                  25                  30

 gca agt ctt gct gtt cac tct ttc gta ctg ccc aag gat gat gtt gct      144
 Ala Ser Leu Ala Val His Ser Phe Val Leu Pro Lys Asp Asp Val Ala
          35                  40                  45

 cca tat ttt aaa acg gag cca ggc cta cca cag atc cac ctg gaa ggg      192
 Pro Tyr Phe Lys Thr Glu Pro Gly Leu Pro Gln Ile His Leu Glu Gly
      50                  55                  60

 aac cgc ctt gtt ctc acc tgc ctt gcc gaa ggg agc tgg cct ttg gag      240
 Asn Arg Leu Val Leu Thr Cys Leu Ala Glu Gly Ser Trp Pro Leu Glu
  65                  70                  75                  80

 ttc aag tgg atg cgc gat gac agt gag ctc acc acc tac agc agc gaa      288
 Phe Lys Trp Met Arg Asp Asp Ser Glu Leu Thr Thr Tyr Ser Ser Glu
                  85                  90                  95

 tat aag taa                                                          297
 Tyr Lys 






      <210> 196
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 196
  atg agg aaa ttc acc aaa tcg ctg ggt agc gta agc atg aat gct ttc      48
  Met Arg Lys Phe Thr Lys Ser Leu Gly Ser Val Ser Met Asn Ala Phe
    1               5                  10                  15

 tct ttc ctc ctg aat ttt gtt ttg ctg ctt ccc aag ttt tcc gga gct       96
 Ser Phe Leu Leu Asn Phe Val Leu Leu Leu Pro Lys Phe Ser Gly Ala
              20                  25                  30

 cgg agg gaa caa ggt tca tgc agg tta cag gtg gca ccc ccg atc agc      144
 Arg Arg Glu Gln Gly Ser Cys Arg Leu Gln Val Ala Pro Pro Ile Ser
          35                  40                  45

 gac aga atc agg tac tct aca aag tgg cgc cca aac agg gac ttc aag      192
 Asp Arg Ile Arg Tyr Ser Thr Lys Trp Arg Pro Asn Arg Asp Phe Lys
      50                  55                  60

 gac atg aag aag aag gtc tgc tgg agc aga gga act gaa att gac aag      240
 Asp Met Lys Lys Lys Val Cys Trp Ser Arg Gly Thr Glu Ile Asp Lys
  65                  70                  75                  80

 gtg aac ggg gat ccc agg gag aag ctg aca caa ctt cag cag cta gtg      288
 Val Asn Gly Asp Pro Arg Glu Lys Leu Thr Gln Leu Gln Gln Leu Val
                  85                  90                  95

 aaa gaa caa tgg gat gcc gga ctc aga gag gag tca gcc cct gga att      336
 Lys Glu Gln Trp Asp Ala Gly Leu Arg Glu Glu Ser Ala Pro Gly Ile
             100                 105                 110

 ctc cag tgt ttg tta tta caa aaa agt cca gaa gat ggc gac tgc tac      384
 Leu Gln Cys Leu Leu Leu Gln Lys Ser Pro Glu Asp Gly Asp Cys Tyr
         115                 120                 125

 atg att taa                                                          393
 Met Ile 
     130





      <210> 197
      <211> 555
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(555)

      <400> 197
  atg acg ctt ggt gtg tca gcc gtc cct gct gcc cgg ttg ctt ctc ttt      48
  Met Thr Leu Gly Val Ser Ala Val Pro Ala Ala Arg Leu Leu Leu Phe
    1               5                  10                  15

 tgg ggg cgg ggt cta gca aga gca ggt gtg ggt tta gga gag gcg cgg       96
 Trp Gly Arg Gly Leu Ala Arg Ala Gly Val Gly Leu Gly Glu Ala Arg
              20                  25                  30

 gta gaa gcg ggg gct ctc ctc aga gct cga cgc att ttt act ttc cct      144
 Val Glu Ala Gly Ala Leu Leu Arg Ala Arg Arg Ile Phe Thr Phe Pro
          35                  40                  45

 ctc att tct ctg acc gaa gct ggg tgt cgg gct ttc gcc tct agc gac      192
 Leu Ile Ser Leu Thr Glu Ala Gly Cys Arg Ala Phe Ala Ser Ser Asp
      50                  55                  60

 tgg tgg aat tgc ctg cat ccg ggc ccc ggg ctt ccc ggc ggc ggc ggc      240
 Trp Trp Asn Cys Leu His Pro Gly Pro Gly Leu Pro Gly Gly Gly Gly
  65                  70                  75                  80

 ggc ggc ggc ggc gca ggg aca agg gat ggg gat ctg gcc tct tcc ttg      288
 Gly Gly Gly Gly Ala Gly Thr Arg Asp Gly Asp Leu Ala Ser Ser Leu
                  85                  90                  95

 ctt tcc cgc cct cag tac ccg agc tgt ctc ctt ccc ggg gac ccg ctg      336
 Leu Ser Arg Pro Gln Tyr Pro Ser Cys Leu Leu Pro Gly Asp Pro Leu
             100                 105                 110

 gga gcg ctg ccg atg cgg gct cga gaa aag gga gcc tcg ggt act gag      384
 Gly Ala Leu Pro Met Arg Ala Arg Glu Lys Gly Ala Ser Gly Thr Glu
         115                 120                 125

 agg cct cgc ctg ggg gaa ggc cgg agg gtg ggc ggc gcg cgg ctt ctg      432
 Arg Pro Arg Leu Gly Glu Gly Arg Arg Val Gly Gly Ala Arg Leu Leu
     130                 135                 140

 cgg acc aag tcg ggg ttc gct agg aac ccg aga cgg tcc ctg ccg gcg      480
 Arg Thr Lys Ser Gly Phe Ala Arg Asn Pro Arg Arg Ser Leu Pro Ala
 145                 150                 155                 160

 agg aga tca tgc ggg atg aga tgg ggg tgt gga gac gcc tgc aca att      528
 Arg Arg Ser Cys Gly Met Arg Trp Gly Cys Gly Asp Ala Cys Thr Ile
                 165                 170                 175

 tca gcc caa gct tct aga gag tgg tga                                  555
 Ser Ala Gln Ala Ser Arg Glu Trp 
             180





      <210> 198
      <211> 945
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(945)

      <400> 198
  atg gcc atc aac atg aga atg cag act tta aga atc ctc acg gca ctc      48
  Met Ala Ile Asn Met Arg Met Gln Thr Leu Arg Ile Leu Thr Ala Leu
    1               5                  10                  15

 ctg tgt ccc tgc gaa tct ggc ctc aag aat gtg tcc tca gat gtc cac       96
 Leu Cys Pro Cys Glu Ser Gly Leu Lys Asn Val Ser Ser Asp Val His
              20                  25                  30

 aga cct agc ttt gag aaa cag gat tcg agc ccc agg gcc agg cca gaa      144
 Arg Pro Ser Phe Glu Lys Gln Asp Ser Ser Pro Arg Ala Arg Pro Glu
          35                  40                  45

 gga agg ggt ggc aaa gag ccc ggc tct ggc tcc cgc agg cca ctc ctt      192
 Gly Arg Gly Gly Lys Glu Pro Gly Ser Gly Ser Arg Arg Pro Leu Leu
      50                  55                  60

 ttg gtg gca gaa cag caa gaa ata cag aaa acc ggg ggg ctg ggt caa      240
 Leu Val Ala Glu Gln Gln Glu Ile Gln Lys Thr Gly Gly Leu Gly Gln
  65                  70                  75                  80

 gcc cca gca ctg gat ata acc aga cga tcc ctt cac tcc acc aag ctt      288
 Ala Pro Ala Leu Asp Ile Thr Arg Arg Ser Leu His Ser Thr Lys Leu
                  85                  90                  95

 cct cag ctg gaa aat ggg gct gct ggc cca cac cgg gga gga ggg acc      336
 Pro Gln Leu Glu Asn Gly Ala Ala Gly Pro His Arg Gly Gly Gly Thr
             100                 105                 110

 aag aag atg gat gtg aga gct ccg tca gct ggc ctt ggt gga ggg ggt      384
 Lys Lys Met Asp Val Arg Ala Pro Ser Ala Gly Leu Gly Gly Gly Gly
         115                 120                 125

 ggt aac agg atg cct tcc caa aat ctc cac ctg gct aat gcc ctc gct      432
 Gly Asn Arg Met Pro Ser Gln Asn Leu His Leu Ala Asn Ala Leu Ala
     130                 135                 140

 gca gct ggg gat ctg cca aaa gtc acc cct gca gaa agc cag ggt gag      480
 Ala Ala Gly Asp Leu Pro Lys Val Thr Pro Ala Glu Ser Gln Gly Glu
 145                 150                 155                 160

 gac cga aag gcc gtc aac ctt gca ggg aag agt ctc cct tac ttg ccc      528
 Asp Arg Lys Ala Val Asn Leu Ala Gly Lys Ser Leu Pro Tyr Leu Pro
                 165                 170                 175

 ctc tct gtc cac tta cac tgc ttt gtt cct ctt cag agc agc atc ttt      576
 Leu Ser Val His Leu His Cys Phe Val Pro Leu Gln Ser Ser Ile Phe
             180                 185                 190

 cac agc tgc caa ggg aag aaa ctg gaa gga tcc ctg tcc aat ggg agc      624
 His Ser Cys Gln Gly Lys Lys Leu Glu Gly Ser Leu Ser Asn Gly Ser
         195                 200                 205

 ctg cgg gac aga tcc ctg tcc aat ggg agc ctg cgg gac aga tcc ctg      672
 Leu Arg Asp Arg Ser Leu Ser Asn Gly Ser Leu Arg Asp Arg Ser Leu
     210                 215                 220

 tcc agt ggg agc ctg cgg gac aga tcc ctg tcc agt ggg agc ctg ggg      720
 Ser Ser Gly Ser Leu Arg Asp Arg Ser Leu Ser Ser Gly Ser Leu Gly
 225                 230                 235                 240

 gac aga tcc ctg tgt gct ctg agt gaa gag gct cag gca gca gca ctg      768
 Asp Arg Ser Leu Cys Ala Leu Ser Glu Glu Ala Gln Ala Ala Ala Leu
                 245                 250                 255

 cag gat gaa gca ccc aag gcc agc agt gag gaa tgg cag gag gcg cac      816
 Gln Asp Glu Ala Pro Lys Ala Ser Ser Glu Glu Trp Gln Glu Ala His
             260                 265                 270

 ccc aca gtt cac ctg acg cag ctg ctg aca ggc ccc aag ttc ctg ctc      864
 Pro Thr Val His Leu Thr Gln Leu Leu Thr Gly Pro Lys Phe Leu Leu
         275                 280                 285

 cct acc tta tgc ctc cag gaa tgg att tct gtc ctc atg cag cag gaa      912
 Pro Thr Leu Cys Leu Gln Glu Trp Ile Ser Val Leu Met Gln Gln Glu
     290                 295                 300

 gga ttc ggg tca gct gag aca tac cgc gtc tag                          945
 Gly Phe Gly Ser Ala Glu Thr Tyr Arg Val 
 305                 310





      <210> 199
      <211> 1041
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1041)

      <400> 199
  atg acg tgg agg gct gcc gcc tcc acg tgc gcg gcg ctc ctg att ctg      48
  Met Thr Trp Arg Ala Ala Ala Ser Thr Cys Ala Ala Leu Leu Ile Leu
    1               5                  10                  15

 ctg tgg gcg ctg acg acc gaa ggt gat ctg aaa gta gag atg atg gca       96
 Leu Trp Ala Leu Thr Thr Glu Gly Asp Leu Lys Val Glu Met Met Ala
              20                  25                  30

 ggg ggg act cag atc aca ccc ctg aat gac aat gtc acc ata ttc tgc      144
 Gly Gly Thr Gln Ile Thr Pro Leu Asn Asp Asn Val Thr Ile Phe Cys
          35                  40                  45

 aat atc ttt tat tcc caa ccc ctc aac atc acg tct atg ggt atc acc      192
 Asn Ile Phe Tyr Ser Gln Pro Leu Asn Ile Thr Ser Met Gly Ile Thr
      50                  55                  60

 tgg ttt tgg aag agt ctg acg ttt gac aaa gaa gtc aaa gtc ttt gaa      240
 Trp Phe Trp Lys Ser Leu Thr Phe Asp Lys Glu Val Lys Val Phe Glu
  65                  70                  75                  80

 ttt ttt gga gat cac caa gag gca ttc cga cct gga gcc att gtg tct      288
 Phe Phe Gly Asp His Gln Glu Ala Phe Arg Pro Gly Ala Ile Val Ser
                  85                  90                  95

 cca tgg agg ctg aag agt ggg gac gcc tca ctg cgg ctg cct gga atc      336
 Pro Trp Arg Leu Lys Ser Gly Asp Ala Ser Leu Arg Leu Pro Gly Ile
             100                 105                 110

 cag ctg gag gaa gca gga gag tac cga tgt gag gtg gtg gtc acc cct      384
 Gln Leu Glu Glu Ala Gly Glu Tyr Arg Cys Glu Val Val Val Thr Pro
         115                 120                 125

 ctg aag gca cag gga aca gtc cag ctt gaa gtt gtg gct tcc cca gcc      432
 Leu Lys Ala Gln Gly Thr Val Gln Leu Glu Val Val Ala Ser Pro Ala
     130                 135                 140

 agc aga ttg ttg ctg gat caa gtg ggc atg aaa gag aat gaa gac aaa      480
 Ser Arg Leu Leu Leu Asp Gln Val Gly Met Lys Glu Asn Glu Asp Lys
 145                 150                 155                 160

 tat atg tgt gag tca agt ggg ttc tac cca gag gct att aat ata aca      528
 Tyr Met Cys Glu Ser Ser Gly Phe Tyr Pro Glu Ala Ile Asn Ile Thr
                 165                 170                 175

 tgg gag aag cag acc cag aag ttt ccc cat ccc ata gag att tct gag      576
 Trp Glu Lys Gln Thr Gln Lys Phe Pro His Pro Ile Glu Ile Ser Glu
             180                 185                 190

 gat gtc atc act ggt ccc acc atc aag aat atg gat ggc aca ttt aat      624
 Asp Val Ile Thr Gly Pro Thr Ile Lys Asn Met Asp Gly Thr Phe Asn
         195                 200                 205

 gtc act agc tgc ttg aag ctg aac tcc tct cag gaa gac cct ggg act      672
 Val Thr Ser Cys Leu Lys Leu Asn Ser Ser Gln Glu Asp Pro Gly Thr
     210                 215                 220

 gtc tac cag tgt gtg gta cgg cat gcg tcc ttg cat acc ccc ttg agg      720
 Val Tyr Gln Cys Val Val Arg His Ala Ser Leu His Thr Pro Leu Arg
 225                 230                 235                 240

 agc aac ttt acc ctg act gct gct cgg cac agt ctt tct ggt atg ttt      768
 Ser Asn Phe Thr Leu Thr Ala Ala Arg His Ser Leu Ser Gly Met Phe
                 245                 250                 255

 ata cct cac ata aat aat tca att gag gga cag cta att ttg aaa gac      816
 Ile Pro His Ile Asn Asn Ser Ile Glu Gly Gln Leu Ile Leu Lys Asp
             260                 265                 270

 aag ttt att act cag aca gcc cct gat atc aga agg aag cta gag aaa      864
 Lys Phe Ile Thr Gln Thr Ala Pro Asp Ile Arg Arg Lys Leu Glu Lys
         275                 280                 285

 cag gcc atg gga tta gat agc acc tta caa aac ctc ctg aag gta gcc      912
 Gln Ala Met Gly Leu Asp Ser Thr Leu Gln Asn Leu Leu Lys Val Ala
     290                 295                 300

 acc tcg gtc ttt tat aat agg gac cag gag gag gcc cag ggg aag gag      960
 Thr Ser Val Phe Tyr Asn Arg Asp Gln Glu Glu Ala Gln Gly Lys Glu
 305                 310                 315                 320

 agg aaa cac aag aaa aag gca gag act ctg gtg gcc act ttg tat aaa     1008
 Arg Lys His Lys Lys Lys Ala Glu Thr Leu Val Ala Thr Leu Tyr Lys
                 325                 330                 335

 acc cag tat ccc caa gaa ccc tca agc agc tga                         1041
 Thr Gln Tyr Pro Gln Glu Pro Ser Ser Ser 
             340                 345





      <210> 200
      <211> 642
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(642)

      <400> 200
  atg atg ata ttg atg atg atg gtg ctg tca ccg caa ctg cca agc ccc      48
  Met Met Ile Leu Met Met Met Val Leu Ser Pro Gln Leu Pro Ser Pro
    1               5                  10                  15

 aaa gga gca tcg agg gag gcc att gga gtt ggc cgc tcg gat ccg ctg       96
 Lys Gly Ala Ser Arg Glu Ala Ile Gly Val Gly Arg Ser Asp Pro Leu
              20                  25                  30

 agc cgc cat ctc gaa act cgc ttc ccg ggt aaa gcc gct aag gct tca      144
 Ser Arg His Leu Glu Thr Arg Phe Pro Gly Lys Ala Ala Lys Ala Ser
          35                  40                  45

 tat ttc ttc ctc cag tta tcc cag cag atg ctg aag ctt ctg cct caa      192
 Tyr Phe Phe Leu Gln Leu Ser Gln Gln Met Leu Lys Leu Leu Pro Gln
      50                  55                  60

 gca aac acg ctg cgc ggc ggc atc cac tcg gca ata tgt ttc ttc ctg      240
 Ala Asn Thr Leu Arg Gly Gly Ile His Ser Ala Ile Cys Phe Phe Leu
  65                  70                  75                  80

 aaa gta gag gag gaa caa aaa agt ccc tta agc aag cga aac atg ggt      288
 Lys Val Glu Glu Glu Gln Lys Ser Pro Leu Ser Lys Arg Asn Met Gly
                  85                  90                  95

 tca atg gcc tca gaa ggc tgc att ctg cac ctg aac gct gtc tgg aga      336
 Ser Met Ala Ser Glu Gly Cys Ile Leu His Leu Asn Ala Val Trp Arg
             100                 105                 110

 gaa ggc atg tgt tac gga ctg aac tgt gtt tcc cga aac tcc tat gtt      384
 Glu Gly Met Cys Tyr Gly Leu Asn Cys Val Ser Arg Asn Ser Tyr Val
         115                 120                 125

 gaa ggt ctg tcc cct aat gtg atg gca ctg gca gga acc aag agg gca      432
 Glu Gly Leu Ser Pro Asn Val Met Ala Leu Ala Gly Thr Lys Arg Ala
     130                 135                 140

 gcg tct gaa cag aca aca tca ctg cat aca gaa gga atc act gac aga      480
 Ala Ser Glu Gln Thr Thr Ser Leu His Thr Glu Gly Ile Thr Asp Arg
 145                 150                 155                 160

 ttc cgg cgg caa act caa gaa gcc gca cac acc ccc tcc gct acg gct      528
 Phe Arg Arg Gln Thr Gln Glu Ala Ala His Thr Pro Ser Ala Thr Ala
                 165                 170                 175

 gct gtc acg cca cgc ata gac tcc aga tca cag aat att ctc cct gtg      576
 Ala Val Thr Pro Arg Ile Asp Ser Arg Ser Gln Asn Ile Leu Pro Val
             180                 185                 190

 gcc tct gcc aat gat cta ccc caa gga aca att aga gaa caa acc aat      624
 Ala Ser Ala Asn Asp Leu Pro Gln Gly Thr Ile Arg Glu Gln Thr Asn
         195                 200                 205

 cca gaa aaa cca acc taa                                              642
 Pro Glu Lys Pro Thr 
     210





      <210> 201
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 201
  atg cac aga gtg ctg cgg ctg tgc cct ctc cta ggc cac cct gtc tgg      48
  Met His Arg Val Leu Arg Leu Cys Pro Leu Leu Gly His Pro Val Trp
    1               5                  10                  15

 tcc ctg gct gct ctg gct ttt gcc ttg tgg ata cag gga gga aaa tca       96
 Ser Leu Ala Ala Leu Ala Phe Ala Leu Trp Ile Gln Gly Gly Lys Ser
              20                  25                  30

 gag ttg ggc agc tgc agc cca agc tca gga tcc tgg gac ttg ggg cag      144
 Glu Leu Gly Ser Cys Ser Pro Ser Ser Gly Ser Trp Asp Leu Gly Gln
          35                  40                  45

 gca ggc aaa gag ctg aac tgt gga ggg cgg gga gct ccc aag tgg att      192
 Ala Gly Lys Glu Leu Asn Cys Gly Gly Arg Gly Ala Pro Lys Trp Ile
      50                  55                  60

 tca ggg aca agt gcc cct gac ccc ggc cac cct gcc cgc tac agt gcc      240
 Ser Gly Thr Ser Ala Pro Asp Pro Gly His Pro Ala Arg Tyr Ser Ala
  65                  70                  75                  80

 tga                                                                  243
 






      <210> 202
      <211> 252
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(252)

      <400> 202
  atg gcc ggg ccg ggc tcg ccg cgc cgc gcg tcc cgg ggg gcc tcg gcg      48
  Met Ala Gly Pro Gly Ser Pro Arg Arg Ala Ser Arg Gly Ala Ser Ala
    1               5                  10                  15

 ctt ctc gct gcc gcg ctt ctc tac gcc gcg ctg ggg gac gtg gtg cgc       96
 Leu Leu Ala Ala Ala Leu Leu Tyr Ala Ala Leu Gly Asp Val Val Arg
              20                  25                  30

 tcg gag cag cag ata ccg ctc tcc gtt tgc aat ata caa ata caa gct      144
 Ser Glu Gln Gln Ile Pro Leu Ser Val Cys Asn Ile Gln Ile Gln Ala
          35                  40                  45

 ctt cag gta atc ttc att gag ctt ctg tgg ggc ctg gct gca tac ata      192
 Leu Gln Val Ile Phe Ile Glu Leu Leu Trp Gly Leu Ala Ala Tyr Ile
      50                  55                  60

 cat gtg tac ttg gtg aat gag caa gtg cat gaa tgg ggg caa gag tat      240
 His Val Tyr Leu Val Asn Glu Gln Val His Glu Trp Gly Gln Glu Tyr
  65                  70                  75                  80

 gga aat gag tga                                                      252
 Gly Asn Glu 






      <210> 203
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 203
  atg agc ggt tgg ctc ggg ctg gtt tcc tcc ctc cac cgc ctg ctt gtt      48
  Met Ser Gly Trp Leu Gly Leu Val Ser Ser Leu His Arg Leu Leu Val
    1               5                  10                  15

 tcg cca tgc ccg ggc cgg acg gtg ggg ctg cag cgg cga aag cga ctg       96
 Ser Pro Cys Pro Gly Arg Thr Val Gly Leu Gln Arg Arg Lys Arg Leu
              20                  25                  30

 aag tcc ggg agc agt cgc atg agc ttc ccg gtc acc agg agg ccc cgg      144
 Lys Ser Gly Ser Ser Arg Met Ser Phe Pro Val Thr Arg Arg Pro Arg
          35                  40                  45

 gaa cag aca cct cac cct gac att gtg gca gct ata cca tct gga aca      192
 Glu Gln Thr Pro His Pro Asp Ile Val Ala Ala Ile Pro Ser Gly Thr
      50                  55                  60

 gat gac ttc caa gga cac cgt agc aaa gaa aaa gag aac tgg aag ccc      240
 Asp Asp Phe Gln Gly His Arg Ser Lys Glu Lys Glu Asn Trp Lys Pro
  65                  70                  75                  80

 atg tgc ctt aat cgc ttc atc cta gag gaa tgt ata gct gct gat gat      288
 Met Cys Leu Asn Arg Phe Ile Leu Glu Glu Cys Ile Ala Ala Asp Asp
                  85                  90                  95

 ttt cga att cgt ggt ctg gaa ccc aac cca caa tac ctt caa gga aag      336
 Phe Arg Ile Arg Gly Leu Glu Pro Asn Pro Gln Tyr Leu Gln Gly Lys
             100                 105                 110

 ccc acc caa gtc tca gag tct ctg agg ctt ttg cga aat gac act cag      384
 Pro Thr Gln Val Ser Glu Ser Leu Arg Leu Leu Arg Asn Asp Thr Gln
         115                 120                 125

 gat ccc aac atc aaa acc agg tac atc atg aat ctt gca aaa aca atc      432
 Asp Pro Asn Ile Lys Thr Arg Tyr Ile Met Asn Leu Ala Lys Thr Ile
     130                 135                 140

 cag aga agt cct gac aag tag                                          453
 Gln Arg Ser Pro Asp Lys 
 145                 150





      <210> 204
      <211> 429
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(429)

      <400> 204
  atg cgg ttg cat tgg cag ctt ctg cag ggt ctg gca cga gcg tgg gag      48
  Met Arg Leu His Trp Gln Leu Leu Gln Gly Leu Ala Arg Ala Trp Glu
    1               5                  10                  15

 ctg ggg agt gca tgt gct tct gcc gtc atg aca cct ctg ctc agg aac       96
 Leu Gly Ser Ala Cys Ala Ser Ala Val Met Thr Pro Leu Leu Arg Asn
              20                  25                  30

 ttt gaa ccc tcg ttt tca ccc agt ccc atc gag aag cca agt gct ccc      144
 Phe Glu Pro Ser Phe Ser Pro Ser Pro Ile Glu Lys Pro Ser Ala Pro
          35                  40                  45

 tcc tca ggc cag agc tcc cag ctg cag aca cag gtt cag ccc cca gct      192
 Ser Ser Gly Gln Ser Ser Gln Leu Gln Thr Gln Val Gln Pro Pro Ala
      50                  55                  60

 gag cga gga gcg gct tcc atg ccg ggg cct gcc tct ctg ccg ctc tcc      240
 Glu Arg Gly Ala Ala Ser Met Pro Gly Pro Ala Ser Leu Pro Leu Ser
  65                  70                  75                  80

 acc ggt cct tcg cag ccg ctc cga tgc tct cca cgg gtc ctt tgc agc      288
 Thr Gly Pro Ser Gln Pro Leu Arg Cys Ser Pro Arg Val Leu Cys Ser
                  85                  90                  95

 cgc gtc ctg gcc ctg agg cgc aga gaa cct cct gga gaa aca gaa gcc      336
 Arg Val Leu Ala Leu Arg Arg Arg Glu Pro Pro Gly Glu Thr Glu Ala
             100                 105                 110

 atg ggt cct gat gcc cga gcc ggc gac gac tct gag cac act gtg agc      384
 Met Gly Pro Asp Ala Arg Ala Gly Asp Asp Ser Glu His Thr Val Ser
         115                 120                 125

 aga gaa cct cct gga gaa aca gag gcc atg ggt cct gac gcc tga          429
 Arg Glu Pro Pro Gly Glu Thr Glu Ala Met Gly Pro Asp Ala 
     130                 135                 140





      <210> 205
      <211> 858
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(858)

      <400> 205
  atg gaa tcg ttc ctc ctc tta ctt tcg gca aca tcc tac ttt gtc tat      48
  Met Glu Ser Phe Leu Leu Leu Leu Ser Ala Thr Ser Tyr Phe Val Tyr
    1               5                  10                  15

 gga gta ggt gtc ctt tca cca ctt tgc ttt ctt aat aaa ctg gct ttt       96
 Gly Val Gly Val Leu Ser Pro Leu Cys Phe Leu Asn Lys Leu Ala Phe
              20                  25                  30

 act tta cac tgc gga ctc gcc ctg aat tct ttc ttg cgt gag atc caa      144
 Thr Leu His Cys Gly Leu Ala Leu Asn Ser Phe Leu Arg Glu Ile Gln
          35                  40                  45

 gaa ccc tct ctt ggg gtc tgg att ggg acc cct gcc cta aaa cat att      192
 Glu Pro Ser Leu Gly Val Trp Ile Gly Thr Pro Ala Leu Lys His Ile
      50                  55                  60

 cct ggc aac cac aga agg gac ttt agt gca gaa acc ctg acc caa cgg      240
 Pro Gly Asn His Arg Arg Asp Phe Ser Ala Glu Thr Leu Thr Gln Arg
  65                  70                  75                  80

 cta cct ttg gga agc tct ccc cca gga cat tct cat cct ctc acc aat      288
 Leu Pro Leu Gly Ser Ser Pro Pro Gly His Ser His Pro Leu Thr Asn
                  85                  90                  95

 cac cag tac aaa tcc aat agc caa tac aaa gcc aaa gcc cca aac cct      336
 His Gln Tyr Lys Ser Asn Ser Gln Tyr Lys Ala Lys Ala Pro Asn Pro
             100                 105                 110

 atc tcc aga gtt tca gtt cca ttt tcc cag ctt ctc aca ggg ctc aag      384
 Ile Ser Arg Val Ser Val Pro Phe Ser Gln Leu Leu Thr Gly Leu Lys
         115                 120                 125

 tcc ctg caa cat aca cac act cca cat aat cat tat tct gaa gtt ggg      432
 Ser Leu Gln His Thr His Thr Pro His Asn His Tyr Ser Glu Val Gly
     130                 135                 140

 gtt tcg gtg caa gta caa acg cat att tat gac tac ctc cta ttc cta      480
 Val Ser Val Gln Val Gln Thr His Ile Tyr Asp Tyr Leu Leu Phe Leu
 145                 150                 155                 160

 aca atc att tta gat atc aat tat tta gcc aag aag aac cag aag agt      528
 Thr Ile Ile Leu Asp Ile Asn Tyr Leu Ala Lys Lys Asn Gln Lys Ser
                 165                 170                 175

 atc ttc ttt gta gta atg agg ctt tgt ctt ctc agg aac tca agt tca      576
 Ile Phe Phe Val Val Met Arg Leu Cys Leu Leu Arg Asn Ser Ser Ser
             180                 185                 190

 gtt cag aaa ctt tca aac atg gtt tta aag gct ttt gaa aac cta atc      624
 Val Gln Lys Leu Ser Asn Met Val Leu Lys Ala Phe Glu Asn Leu Ile
         195                 200                 205

 tct cct agt gct gtt aca ttt ctt aac gtg gca ata gct gta act cat      672
 Ser Pro Ser Ala Val Thr Phe Leu Asn Val Ala Ile Ala Val Thr His
     210                 215                 220

 acc ctt aaa acc ttg cac agt gct gtg gat tca att gtc ctg ctt ctt      720
 Thr Leu Lys Thr Leu His Ser Ala Val Asp Ser Ile Val Leu Leu Leu
 225                 230                 235                 240

 tcc tgg agc att ggt aag cgt cac act gcc aaa gtg aga gct gct gga      768
 Ser Trp Ser Ile Gly Lys Arg His Thr Ala Lys Val Arg Ala Ala Gly
                 245                 250                 255

 gaa ctc ata atc cca gga acg cct ctt cta ctc tcc gag tac ccc agt      816
 Glu Leu Ile Ile Pro Gly Thr Pro Leu Leu Leu Ser Glu Tyr Pro Ser
             260                 265                 270

 gac cag agt gag aga agc tct gaa cga ggg cac gcg gct tga              858
 Asp Gln Ser Glu Arg Ser Ser Glu Arg Gly His Ala Ala 
         275                 280                 285





      <210> 206
      <211> 789
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(789)

      <400> 206
  atg ggg cgc gag cgc gat ccg agc ggc tgg acc tgg ctg ctc cgc tgt      48
  Met Gly Arg Glu Arg Asp Pro Ser Gly Trp Thr Trp Leu Leu Arg Cys
    1               5                  10                  15

 gcc gcg gcc gct tgc gcc cta ctt ctg ggc tcc cag cgc cag gaa acc       96
 Ala Ala Ala Ala Cys Ala Leu Leu Leu Gly Ser Gln Arg Gln Glu Thr
              20                  25                  30

 cag ctg ctc ctc tcg gag cac tcg gac cct gac att gag cac cga gtt      144
 Gln Leu Leu Leu Ser Glu His Ser Asp Pro Asp Ile Glu His Arg Val
          35                  40                  45

 agg gga gaa cca aaa agg act acc agg tgg tta ggt gtt gag tgt tgg      192
 Arg Gly Glu Pro Lys Arg Thr Thr Arg Trp Leu Gly Val Glu Cys Trp
      50                  55                  60

 agg caa gga gta att aac att gag aca aaa gct caa gaa caa ctc cag      240
 Arg Gln Gly Val Ile Asn Ile Glu Thr Lys Ala Gln Glu Gln Leu Gln
  65                  70                  75                  80

 ccc aag ggg aaa aag gtt tcc agt ctt ttg acc gcg ctt ccg ggg tct      288
 Pro Lys Gly Lys Lys Val Ser Ser Leu Leu Thr Ala Leu Pro Gly Ser
                  85                  90                  95

 ata gat gag ctc agt ttg aaa cga gat gta aag gag tcg att tct ttg      336
 Ile Asp Glu Leu Ser Leu Lys Arg Asp Val Lys Glu Ser Ile Ser Leu
             100                 105                 110

 ccg gcg gtt ccc ttc caa att gag tta ctt ctt ata agc aaa att aat      384
 Pro Ala Val Pro Phe Gln Ile Glu Leu Leu Leu Ile Ser Lys Ile Asn
         115                 120                 125

 atg caa aca aga ctg ctg cag ctg ccg ctg aaa ttc gct gtg gcc gct      432
 Met Gln Thr Arg Leu Leu Gln Leu Pro Leu Lys Phe Ala Val Ala Ala
     130                 135                 140

 gcc tct tcc cgc ttt aat ccc aga cct cca gtc att ggg cag ctc ctc      480
 Ala Ser Ser Arg Phe Asn Pro Arg Pro Pro Val Ile Gly Gln Leu Leu
 145                 150                 155                 160

 aga ggc aag aag tca aca cca tgg caa ccc gac aag cct atc aaa tca      528
 Arg Gly Lys Lys Ser Thr Pro Trp Gln Pro Asp Lys Pro Ile Lys Ser
                 165                 170                 175

 ccg gct ggc gtg aca gca gca aca ctg cag gca gga gtg ggc tgg gcg      576
 Pro Ala Gly Val Thr Ala Ala Thr Leu Gln Ala Gly Val Gly Trp Ala
             180                 185                 190

 gaa gag cag agt ggc cac tgc gct cag gta cac agt ctg gga gtg gac      624
 Glu Glu Gln Ser Gly His Cys Ala Gln Val His Ser Leu Gly Val Asp
         195                 200                 205

 agc agc tgc tgg tct cca cgt tct ggc tac aca tat gtg cac cac cca      672
 Ser Ser Cys Trp Ser Pro Arg Ser Gly Tyr Thr Tyr Val His His Pro
     210                 215                 220

 gtc cat acc cct acc tta tgt gcc cta gta ggt tct gga gga gaa agg      720
 Val His Thr Pro Thr Leu Cys Ala Leu Val Gly Ser Gly Gly Glu Arg
 225                 230                 235                 240

 gga gga gga gaa gga gag aag cat ata ggc ttg gag gaa cag gaa ccg      768
 Gly Gly Gly Glu Gly Glu Lys His Ile Gly Leu Glu Glu Gln Glu Pro
                 245                 250                 255

 cag aaa aga gtt tta aac taa                                          789
 Gln Lys Arg Val Leu Asn 
             260





      <210> 207
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 207
  atg cct ttg cca tgg gtg gcc ttc tgt tct gtg gac atg gtg ccc aca      48
  Met Pro Leu Pro Trp Val Ala Phe Cys Ser Val Asp Met Val Pro Thr
    1               5                  10                  15

 ttg aag gct tgc tgt gca gtg ctc gtt ctc aca tct ggc ttt ggg aga       96
 Leu Lys Ala Cys Cys Ala Val Leu Val Leu Thr Ser Gly Phe Gly Arg
              20                  25                  30

 aag gag gag atg aac agg aac atc atg gag gac caa cca atc aca ggc      144
 Lys Glu Glu Met Asn Arg Asn Ile Met Glu Asp Gln Pro Ile Thr Gly
          35                  40                  45

 atc ctg gcg tgt gtt caa gca cag tgc ccc gta ctg gag ctg gat gtc      192
 Ile Leu Ala Cys Val Gln Ala Gln Cys Pro Val Leu Glu Leu Asp Val
      50                  55                  60

 tgt gta gcg tct agt cct gcc att aag tac tgt gtt gat ctg gga cac      240
 Cys Val Ala Ser Ser Pro Ala Ile Lys Tyr Cys Val Asp Leu Gly His
  65                  70                  75                  80

 agt gac gtt gac ccc att ctc cag ggt tcg ccg ccc ccc act gag gcc      288
 Ser Asp Val Asp Pro Ile Leu Gln Gly Ser Pro Pro Pro Thr Glu Ala
                  85                  90                  95

 cag gat ggc cag gtc acc ttc tga                                      312
 Gln Asp Gly Gln Val Thr Phe 
             100





      <210> 208
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 208
  atg tct tta aaa acc acg tgt gcc cat gta ctg gtt cga aag tct cta      48
  Met Ser Leu Lys Thr Thr Cys Ala His Val Leu Val Arg Lys Ser Leu
    1               5                  10                  15

 ctc ttc atc cct aca gcc aaa gga ccc gtc att aac gcc ccg ctt cct       96
 Leu Phe Ile Pro Thr Ala Lys Gly Pro Val Ile Asn Ala Pro Leu Pro
              20                  25                  30

 cag cga ctg cgt tca aat aca gcc cca atc agg acg ctc cac gca cca      144
 Gln Arg Leu Arg Ser Asn Thr Ala Pro Ile Arg Thr Leu His Ala Pro
          35                  40                  45

 tcg gta cac aga ccc aca ggc cgc gag tcc atg ccc aga act cga ctc      192
 Ser Val His Arg Pro Thr Gly Arg Glu Ser Met Pro Arg Thr Arg Leu
      50                  55                  60

 acc cga gcc cga acc tct cca gac acc act ggc agc gac aaa acg ccg      240
 Thr Arg Ala Arg Thr Ser Pro Asp Thr Thr Gly Ser Asp Lys Thr Pro
  65                  70                  75                  80

 cat cca cgt ccg aaa acg ctt cct att cag acg cgc tcc tgc gcg gac      288
 His Pro Arg Pro Lys Thr Leu Pro Ile Gln Thr Arg Ser Cys Ala Asp
                  85                  90                  95

 tcc ggg aag ctg agc ggt aaa gac cgt gaa gcg agg cga gga cca cgg      336
 Ser Gly Lys Leu Ser Gly Lys Asp Arg Glu Ala Arg Arg Gly Pro Arg
             100                 105                 110

 agc ctg ccc ggg atc gcg agt tca gac tgc ggg cgc cgc tct atg agg      384
 Ser Leu Pro Gly Ile Ala Ser Ser Asp Cys Gly Arg Arg Ser Met Arg
         115                 120                 125

 tca cag ggc tgc gcc cat cgc agc gtt tct gac agg agc ggc cat aat      432
 Ser Gln Gly Cys Ala His Arg Ser Val Ser Asp Arg Ser Gly His Asn
     130                 135                 140

 ggc tgt ggg aat cac tct tag                                          453
 Gly Cys Gly Asn His Ser 
 145                 150





      <210> 209
      <211> 906
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(906)

      <400> 209
  atg ggc tgg gca cgg tgg ctc acg cct gta atc cca gca ctt tgg gag      48
  Met Gly Trp Ala Arg Trp Leu Thr Pro Val Ile Pro Ala Leu Trp Glu
    1               5                  10                  15

 gcc gag gtg ggt gga tca cct aag agc cct tat att ttg gat tct tac       96
 Ala Glu Val Gly Gly Ser Pro Lys Ser Pro Tyr Ile Leu Asp Ser Tyr
              20                  25                  30

 gag cta acc cgg gct tcc acc ctg act ctc atc act acc aca ccc atg      144
 Glu Leu Thr Arg Ala Ser Thr Leu Thr Leu Ile Thr Thr Thr Pro Met
          35                  40                  45

 tgt ctt tcc tct ctc cgt ctc cct gag acg cca gtg aac cac ctg ggc      192
 Cys Leu Ser Ser Leu Arg Leu Pro Glu Thr Pro Val Asn His Leu Gly
      50                  55                  60

 ttg gaa tcc aga gcc ccg gaa cac ctt gca gta ctt gcc cga agc aac      240
 Leu Glu Ser Arg Ala Pro Glu His Leu Ala Val Leu Ala Arg Ser Asn
  65                  70                  75                  80

 gcg cca aca gcg gga ggg aga cgc aga cgc gaa gac cgg cga gag gat      288
 Ala Pro Thr Ala Gly Gly Arg Arg Arg Arg Glu Asp Arg Arg Glu Asp
                  85                  90                  95

 gtg cgc tct cgc gcc cga cga ggt gga ttt ggc tgt cca ccg agc tcc      336
 Val Arg Ser Arg Ala Arg Arg Gly Gly Phe Gly Cys Pro Pro Ser Ser
             100                 105                 110

 ggc gcc tgt cgt tct aat tgg gtt tgg att tgc acc gtt aag gag ggg      384
 Gly Ala Cys Arg Ser Asn Trp Val Trp Ile Cys Thr Val Lys Glu Gly
         115                 120                 125

 gga aga gaa gga aga ggc ggg cga gga agg cga gtc cag cta gcg gct      432
 Gly Arg Glu Gly Arg Gly Gly Arg Gly Arg Arg Val Gln Leu Ala Ala
     130                 135                 140

 gtt gcg ggg acc gta gcc cca gct gca gct ccg aag aat ccc ccg cca      480
 Val Ala Gly Thr Val Ala Pro Ala Ala Ala Pro Lys Asn Pro Pro Pro
 145                 150                 155                 160

 cgg ttt cgg tgg agc gtc tgg gca cgg gat gga gtg aaa gag cga gtg      528
 Arg Phe Arg Trp Ser Val Trp Ala Arg Asp Gly Val Lys Glu Arg Val
                 165                 170                 175

 cct ctc caa gcg ggg gtg gga ggg ggt cag gct gtg cag agg aga gag      576
 Pro Leu Gln Ala Gly Val Gly Gly Gly Gln Ala Val Gln Arg Arg Glu
             180                 185                 190

 aca gcg aga aga agc cgc ggc tgg cta ctg cga att tgg gat tcg att      624
 Thr Ala Arg Arg Ser Arg Gly Trp Leu Leu Arg Ile Trp Asp Ser Ile
         195                 200                 205

 ggg agg gac cgc tca ctc ggg gga aat gga ttc ttt acc acg gct gac      672
 Gly Arg Asp Arg Ser Leu Gly Gly Asn Gly Phe Phe Thr Thr Ala Asp
     210                 215                 220

 cag cgt ttt gac ttt gct gtt ctc tgg ctt gtg gca ttt agg att aac      720
 Gln Arg Phe Asp Phe Ala Val Leu Trp Leu Val Ala Phe Arg Ile Asn
 225                 230                 235                 240

 agc gac aaa ctt ggc tca tct ctg aat gca gtg cct cgg att tgc agt      768
 Ser Asp Lys Leu Gly Ser Ser Leu Asn Ala Val Pro Arg Ile Cys Ser
                 245                 250                 255

 ata cca agc acc cca cga tac gtg gct ctg cgt tct gcc cta ggc aga      816
 Ile Pro Ser Thr Pro Arg Tyr Val Ala Leu Arg Ser Ala Leu Gly Arg
             260                 265                 270

 agg ctc cag ttg ggg tat ctt gca acc aat ggg cac cgg ttt aac agg      864
 Arg Leu Gln Leu Gly Tyr Leu Ala Thr Asn Gly His Arg Phe Asn Arg
         275                 280                 285

 att ggg agt ttt ggc cta aga gtc atg gac caa tgt tgt taa              906
 Ile Gly Ser Phe Gly Leu Arg Val Met Asp Gln Cys Cys 
     290                 295                 300





      <210> 210
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 210
  atg cag cct gga gcc aga gag cag aaa gct ggg ctg gtt ctg aag ctt      48
  Met Gln Pro Gly Ala Arg Glu Gln Lys Ala Gly Leu Val Leu Lys Leu
    1               5                  10                  15

 ctt cca tac tta agt tgc ctc caa gca gtt tgt gaa agt atc aga tct       96
 Leu Pro Tyr Leu Ser Cys Leu Gln Ala Val Cys Glu Ser Ile Arg Ser
              20                  25                  30

 tgg tat cct gta aca ctt tct agc tcc acg gat aag gaa tca ctg aac      144
 Trp Tyr Pro Val Thr Leu Ser Ser Ser Thr Asp Lys Glu Ser Leu Asn
          35                  40                  45

 cta gta gtt ctt aga cag ctt ggt ttg aga atc ctt ttg cgg tta aaa      192
 Leu Val Val Leu Arg Gln Leu Gly Leu Arg Ile Leu Leu Arg Leu Lys
      50                  55                  60

 att agg gac tga                                                      204
 Ile Arg Asp 
  65





      <210> 211
      <211> 345
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(345)

      <400> 211
  atg atg agg ttg tcc cta gtt gtt ctc aaa gtt gct gtt acc ttg aaa      48
  Met Met Arg Leu Ser Leu Val Val Leu Lys Val Ala Val Thr Leu Lys
    1               5                  10                  15

 aat gac ttc cct ggg aac cag aac atc cag gtt ggc ctc aaa ctt gct       96
 Asn Asp Phe Pro Gly Asn Gln Asn Ile Gln Val Gly Leu Lys Leu Ala
              20                  25                  30

 gcc aaa cag gaa ctg tgg caa gcc gga gag gat tct gat gct tgg aac      144
 Ala Lys Gln Glu Leu Trp Gln Ala Gly Glu Asp Ser Asp Ala Trp Asn
          35                  40                  45

 ttc ttg tcc tat cgg cca acc ccc gac ctg aag gcc agt gtc aaa gtg      192
 Phe Leu Ser Tyr Arg Pro Thr Pro Asp Leu Lys Ala Ser Val Lys Val
      50                  55                  60

 tca ggg tgt caa agt gca gaa ttg tca ggc aag atg atg atg aat gaa      240
 Ser Gly Cys Gln Ser Ala Glu Leu Ser Gly Lys Met Met Met Asn Glu
  65                  70                  75                  80

 gtc ctg gca gct tcc tgt gtc cca ggc ctt gta gaa ata aat gag aca      288
 Val Leu Ala Ala Ser Cys Val Pro Gly Leu Val Glu Ile Asn Glu Thr
                  85                  90                  95

 gac gtg ctt caa agt tct aat gtg cat cac atc gga tct tgt tta agg      336
 Asp Val Leu Gln Ser Ser Asn Val His His Ile Gly Ser Cys Leu Arg
             100                 105                 110

 aag cgt taa                                                          345
 Lys Arg 






      <210> 212
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 212
  atg acg tgg gta cag aat gac aga atg gga gtc aga tgt ttc ttg atg      48
  Met Thr Trp Val Gln Asn Asp Arg Met Gly Val Arg Cys Phe Leu Met
    1               5                  10                  15

 cta gta cat gct tgc tgg aag gca gtt atg agc cta att tgc agg aat       96
 Leu Val His Ala Cys Trp Lys Ala Val Met Ser Leu Ile Cys Arg Asn
              20                  25                  30

 gaa gag tat cat ggg aac ctc agt gtt ggt ccc aca gct gta agc caa      144
 Glu Glu Tyr His Gly Asn Leu Ser Val Gly Pro Thr Ala Val Ser Gln
          35                  40                  45

 ttc ccc caa ttt ttc aca gcc ctc att ttc cag gaa gac att agc ttt      192
 Phe Pro Gln Phe Phe Thr Ala Leu Ile Phe Gln Glu Asp Ile Ser Phe
      50                  55                  60

 agg ggg aag aaa tca gag gcc cca gag cag cct gtc att tgt cta ggt      240
 Arg Gly Lys Lys Ser Glu Ala Pro Glu Gln Pro Val Ile Cys Leu Gly
  65                  70                  75                  80

 tgg ctc ctg tgg gtt cca ggc aga ctc taa                              270
 Trp Leu Leu Trp Val Pro Gly Arg Leu 
                  85





      <210> 213
      <211> 735
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(735)

      <400> 213
  atg cta agg acc tgg agc tct cta ccc tgg acc cgt ttt cgg gtt tgc      48
  Met Leu Arg Thr Trp Ser Ser Leu Pro Trp Thr Arg Phe Arg Val Cys
    1               5                  10                  15

 ttg ctc tct ctc tct ctc ttt ctc tgg gct aat cgt tta gag gac agt       96
 Leu Leu Ser Leu Ser Leu Phe Leu Trp Ala Asn Arg Leu Glu Asp Ser
              20                  25                  30

 cgc tcc tgc caa cct aat ccc atg agc ctg act acc ttg ccg ggc cac      144
 Arg Ser Cys Gln Pro Asn Pro Met Ser Leu Thr Thr Leu Pro Gly His
          35                  40                  45

 agg ctc aaa gaa gca gtg tgg ctg cca gca ccc tca cgg gct ttg gca      192
 Arg Leu Lys Glu Ala Val Trp Leu Pro Ala Pro Ser Arg Ala Leu Ala
      50                  55                  60

 tca gtt aaa atg cca acc tct tgg gag gat cag cct ctt aaa tct ccc      240
 Ser Val Lys Met Pro Thr Ser Trp Glu Asp Gln Pro Leu Lys Ser Pro
  65                  70                  75                  80

 atc gtg aaa gca ggt tct gat aga ggg aca aag aga gag gag gaa cat      288
 Ile Val Lys Ala Gly Ser Asp Arg Gly Thr Lys Arg Glu Glu Glu His
                  85                  90                  95

 gaa atc att cta gag cct gtt cca ctt ctt gcc cag acc ctg gag atg      336
 Glu Ile Ile Leu Glu Pro Val Pro Leu Leu Ala Gln Thr Leu Glu Met
             100                 105                 110

 gtc tcc caa ttg gtc cgc atg cag ctg gcc tct ctt ccc tcc aat ctt      384
 Val Ser Gln Leu Val Arg Met Gln Leu Ala Ser Leu Pro Ser Asn Leu
         115                 120                 125

 tca aca ccc tgc acc atg agt cct cac ctt gac cct aat caa ctt ggg      432
 Ser Thr Pro Cys Thr Met Ser Pro His Leu Asp Pro Asn Gln Leu Gly
     130                 135                 140

 att ctc ctc aaa gta ctt aga aag gaa aag gaa gac ggt gac tac cct      480
 Ile Leu Leu Lys Val Leu Arg Lys Glu Lys Glu Asp Gly Asp Tyr Pro
 145                 150                 155                 160

 gac atg atg gcc acc cac ccg agc tcc agg tat gaa gcc tgc tcc tct      528
 Asp Met Met Ala Thr His Pro Ser Ser Arg Tyr Glu Ala Cys Ser Ser
                 165                 170                 175

 gga att act cta gag aag cct gag aaa ttg cgg agt ggg aag gtg aag      576
 Gly Ile Thr Leu Glu Lys Pro Glu Lys Leu Arg Ser Gly Lys Val Lys
             180                 185                 190

 gaa gaa gtt gac tcc ctt att ggg tca gct ttt cct gtc aca cct caa      624
 Glu Glu Val Asp Ser Leu Ile Gly Ser Ala Phe Pro Val Thr Pro Gln
         195                 200                 205

 ggt ggt tgg caa agg cag agc tgg ttt ggc aag gac cgg gac cag aag      672
 Gly Gly Trp Gln Arg Gln Ser Trp Phe Gly Lys Asp Arg Asp Gln Lys
     210                 215                 220

 agg gat gaa cag gtg tct gca aca gat tcc ttt gaa gaa tac ttt aat      720
 Arg Asp Glu Gln Val Ser Ala Thr Asp Ser Phe Glu Glu Tyr Phe Asn
 225                 230                 235                 240

 ggc ctt atg cca taa                                                  735
 Gly Leu Met Pro 






      <210> 214
      <211> 129
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(129)

      <400> 214
  atg ccc agg gcg ttt gtc cac acc aga ttc ctt cgc tgc atc ttt ttt      48
  Met Pro Arg Ala Phe Val His Thr Arg Phe Leu Arg Cys Ile Phe Phe
    1               5                  10                  15

 ttt aaa cac caa cca gag ccc ggc gga ttg atg cac act gtg gaa gac       96
 Phe Lys His Gln Pro Glu Pro Gly Gly Leu Met His Thr Val Glu Asp
              20                  25                  30

 acg cag aag ccc aag tat ctg caa cgc ctg taa                          129
 Thr Gln Lys Pro Lys Tyr Leu Gln Arg Leu 
          35                  40





      <210> 215
      <211> 675
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(675)

      <400> 215
  atg act gcc ttt gca ctg tcc atg ctc tca gcc cac cac ctc ctc ccc      48
  Met Thr Ala Phe Ala Leu Ser Met Leu Ser Ala His His Leu Leu Pro
    1               5                  10                  15

 ctg cca ttg cag tgg cta aca ctg gag acg aag acc aag aca cca cag       96
 Leu Pro Leu Gln Trp Leu Thr Leu Glu Thr Lys Thr Lys Thr Pro Gln
              20                  25                  30

 cct ttc tcc agt acc tct caa atc agc aca gac aag gac aaa ggc ctc      144
 Pro Phe Ser Ser Thr Ser Gln Ile Ser Thr Asp Lys Asp Lys Gly Leu
          35                  40                  45

 aat cca caa ctg ctg aag atg gac cct ggc cac atg gga tgg tca gac      192
 Asn Pro Gln Leu Leu Lys Met Asp Pro Gly His Met Gly Trp Ser Asp
      50                  55                  60

 acg cct gcc cag cta tct gca ggc gaa gag gct cag aag agg ttt aag      240
 Thr Pro Ala Gln Leu Ser Ala Gly Glu Glu Ala Gln Lys Arg Phe Lys
  65                  70                  75                  80

 cct gca aca tct gaa gcc ctg gac ctg gaa ccg gag act ccc acc agc      288
 Pro Ala Thr Ser Glu Ala Leu Asp Leu Glu Pro Glu Thr Pro Thr Ser
                  85                  90                  95

 cac tat acc tgt gaa ccc gta gaa gac ctg aac tac cta ttt aaa aga      336
 His Tyr Thr Cys Glu Pro Val Glu Asp Leu Asn Tyr Leu Phe Lys Arg
             100                 105                 110

 cag tca aaa gat aaa gtc aat ggc ttc ctt ctg tct tat cca gtg aac      384
 Gln Ser Lys Asp Lys Val Asn Gly Phe Leu Leu Ser Tyr Pro Val Asn
         115                 120                 125

 tgt gag ctc cct aag aaa agg aac aga gtc ttc ctc ttg ttt ttc acc      432
 Cys Glu Leu Pro Lys Lys Arg Asn Arg Val Phe Leu Leu Phe Phe Thr
     130                 135                 140

 ctc aat gtc cat aga tat gcc aca cag aaa gcc aca cac aga aga cag      480
 Leu Asn Val His Arg Tyr Ala Thr Gln Lys Ala Thr His Arg Arg Gln
 145                 150                 155                 160

 gtt gca tat gtc acc tgc act gtg gtc cag gag tct caa gtc acc atc      528
 Val Ala Tyr Val Thr Cys Thr Val Val Gln Glu Ser Gln Val Thr Ile
                 165                 170                 175

 ccc acc atg gtc agt cgc ctg ggc ctg gcg cag aag cac cct ttg tcc      576
 Pro Thr Met Val Ser Arg Leu Gly Leu Ala Gln Lys His Pro Leu Ser
             180                 185                 190

 ctg ggt ggc ctg atc ctg ctg acc acg ggt cac ctc cct gac cac gaa      624
 Leu Gly Gly Leu Ile Leu Leu Thr Thr Gly His Leu Pro Asp His Glu
         195                 200                 205

 tac tct gcc aac tgt ccc cga gtg acc aag gca gct cag tct aga gtc      672
 Tyr Ser Ala Asn Cys Pro Arg Val Thr Lys Ala Ala Gln Ser Arg Val
     210                 215                 220

 tag                                                                  675
 






      <210> 216
      <211> 333
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(333)

      <400> 216
  atg ggc cca gca aca tgg tgg gtc ctg gaa gct ctg gat ctg gac ctg      48
  Met Gly Pro Ala Thr Trp Trp Val Leu Glu Ala Leu Asp Leu Asp Leu
    1               5                  10                  15

 gct ggg gcc ctg gta ggt gcc tgg gaa gtt gac agg cct gtc aaa ggg       96
 Ala Gly Ala Leu Val Gly Ala Trp Glu Val Asp Arg Pro Val Lys Gly
              20                  25                  30

 gct ttg tca tct cag aaa cct gac cgc ttt gag ggt aaa ggc acc ccg      144
 Ala Leu Ser Ser Gln Lys Pro Asp Arg Phe Glu Gly Lys Gly Thr Pro
          35                  40                  45

 gag gaa ttt gga ccg agg gtg gcc tgt gat cag ctc ttt cga gag tct      192
 Glu Glu Phe Gly Pro Arg Val Ala Cys Asp Gln Leu Phe Arg Glu Ser
      50                  55                  60

 tcc gtc agc cac tgt ggc agc acc tgg aag aag aaa cag aag cag agc      240
 Ser Val Ser His Cys Gly Ser Thr Trp Lys Lys Lys Gln Lys Gln Ser
  65                  70                  75                  80

 gga aaa gga agg aac tcc cca gag cag gaa aag aaa ttc ctt tta aaa      288
 Gly Lys Gly Arg Asn Ser Pro Glu Gln Glu Lys Lys Phe Leu Leu Lys
                  85                  90                  95

 cat ctt ttt tgc ttc ccc gtc cct gga atc tcc atc att cat tga          333
 His Leu Phe Cys Phe Pro Val Pro Gly Ile Ser Ile Ile His 
             100                 105                 110





      <210> 217
      <211> 726
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(726)

      <400> 217
  atg agg ggc ctt gtg gta ttc ctt gca gtc ttt gct ctc tct gag gtc      48
  Met Arg Gly Leu Val Val Phe Leu Ala Val Phe Ala Leu Ser Glu Val
    1               5                  10                  15

 aat gcc atc acc agg gtt cct ctg cac aaa ggg aag tcg ctg agg agg       96
 Asn Ala Ile Thr Arg Val Pro Leu His Lys Gly Lys Ser Leu Arg Arg
              20                  25                  30

 gcc ctg aag gag cgc agg ctc ctg gag gac ttc ctg agg aat cac cat      144
 Ala Leu Lys Glu Arg Arg Leu Leu Glu Asp Phe Leu Arg Asn His His
          35                  40                  45

 tat gca gtc agc agg aag cac tcc agc tct ggg gtg gtg gcc agc gag      192
 Tyr Ala Val Ser Arg Lys His Ser Ser Ser Gly Val Val Ala Ser Glu
      50                  55                  60

 tct ctg acc aac tac ctg gat tgt cag tac ttt ggg aag atc tac atc      240
 Ser Leu Thr Asn Tyr Leu Asp Cys Gln Tyr Phe Gly Lys Ile Tyr Ile
  65                  70                  75                  80

 ggg acc ctt ccc cag aag ttc acc ttg gtg ttt gat aca ggc tcc ccg      288
 Gly Thr Leu Pro Gln Lys Phe Thr Leu Val Phe Asp Thr Gly Ser Pro
                  85                  90                  95

 gat atc tgg gtg ccc tct gtc tac tgc aac agt gat gcc tgt cag aga      336
 Asp Ile Trp Val Pro Ser Val Tyr Cys Asn Ser Asp Ala Cys Gln Arg
             100                 105                 110

 att gcc agt att gag gcc ata ttc tta caa ggc ctg ctg agg ggt tcg      384
 Ile Ala Ser Ile Glu Ala Ile Phe Leu Gln Gly Leu Leu Arg Gly Ser
         115                 120                 125

 gcc ctg gct ggc acc gtg agt ggt gag aag att cta agg gcc cca cta      432
 Ala Leu Ala Gly Thr Val Ser Gly Glu Lys Ile Leu Arg Ala Pro Leu
     130                 135                 140

 act ctg ggt ctg tgt ttc aga aaa cca cca acg ctt cga tcc gtc caa      480
 Thr Leu Gly Leu Cys Phe Arg Lys Pro Pro Thr Leu Arg Ser Val Gln
 145                 150                 155                 160

 gtc ctc cac cca cag aac atg ggc aag tcc ctg tcc atc cag tat ggc      528
 Val Leu His Pro Gln Asn Met Gly Lys Ser Leu Ser Ile Gln Tyr Gly
                 165                 170                 175

 aca ggc agc atg cgg ggc ttg ctg ggc tat gac act gtc acc gac cta      576
 Thr Gly Ser Met Arg Gly Leu Leu Gly Tyr Asp Thr Val Thr Asp Leu
             180                 185                 190

 gtg gag gtc atg att ctc ttg cag gtc tcc aac att gtg gac ccc cac      624
 Val Glu Val Met Ile Leu Leu Gln Val Ser Asn Ile Val Asp Pro His
         195                 200                 205

 cag act gtg ggt ctg agc acc cag gaa cct ggc gac gtc ttc acc tac      672
 Gln Thr Val Gly Leu Ser Thr Gln Glu Pro Gly Asp Val Phe Thr Tyr
     210                 215                 220

 tcc gag ttt gat ggg atc ctg ggg ctg gcc tat ccc tct ctt gcc tct      720
 Ser Glu Phe Asp Gly Ile Leu Gly Leu Ala Tyr Pro Ser Leu Ala Ser
 225                 230                 235                 240

 gag tag                                                              726
 Glu 






      <210> 218
      <211> 399
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(399)

      <400> 218
  atg ggg gtt ctc ctg gca ctg ggc ctg gag gct ggt gtc cgc ttg gcc      48
  Met Gly Val Leu Leu Ala Leu Gly Leu Glu Ala Gly Val Arg Leu Ala
    1               5                  10                  15

 ttt ctg gca gcc cag ccc ggg cag tct tca aag aca gca gct gca gcc       96
 Phe Leu Ala Ala Gln Pro Gly Gln Ser Ser Lys Thr Ala Ala Ala Ala
              20                  25                  30

 ttc acc ctc tgg cca cgg gca ttg gga ggg gtg gcg cag gtg gcc ccc      144
 Phe Thr Leu Trp Pro Arg Ala Leu Gly Gly Val Ala Gln Val Ala Pro
          35                  40                  45

 acc cgc agg ttc agc cca gta agc cac ctg aag aga aaa gag agc tgg      192
 Thr Arg Arg Phe Ser Pro Val Ser His Leu Lys Arg Lys Glu Ser Trp
      50                  55                  60

 gga gct agc tgt gct gat tct gct cca gtg gcc tgg agc agg tgg gca      240
 Gly Ala Ser Cys Ala Asp Ser Ala Pro Val Ala Trp Ser Arg Trp Ala
  65                  70                  75                  80

 ctg ggt gtg ggg cag ggt tgg tgc aga agg cag cac aag gcc aca ggc      288
 Leu Gly Val Gly Gln Gly Trp Cys Arg Arg Gln His Lys Ala Thr Gly
                  85                  90                  95

 agc atg cat tca ttc gct caa caa gca ttt gcc agc ttt cct gag gag      336
 Ser Met His Ser Phe Ala Gln Gln Ala Phe Ala Ser Phe Pro Glu Glu
             100                 105                 110

 gtc aag gag gcc acc agg aat ttg gga gcg gtg gag cct ata ggt gac      384
 Val Lys Glu Ala Thr Arg Asn Leu Gly Ala Val Glu Pro Ile Gly Asp
         115                 120                 125

 agc agg ctc tgc tga                                                  399
 Ser Arg Leu Cys 
     130





      <210> 219
      <211> 234
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(234)

      <400> 219
  atg att ttc tgc ctg atc ctg gac atc tgc agc ctc tta act gaa tcc      48
  Met Ile Phe Cys Leu Ile Leu Asp Ile Cys Ser Leu Leu Thr Glu Ser
    1               5                  10                  15

 aag tca gtt aat tat cag atc caa tcc aat cat gga tcc agt cca gtt       96
 Lys Ser Val Asn Tyr Gln Ile Gln Ser Asn His Gly Ser Ser Pro Val
              20                  25                  30

 tct gtt gtg act tcc aaa ccc agt tcg gat cag aag ttt gct caa act      144
 Ser Val Val Thr Ser Lys Pro Ser Ser Asp Gln Lys Phe Ala Gln Thr
          35                  40                  45

 cgg ttc caa aca gaa atc tgt cga gct tca gaa tct cag cga gaa ctt      192
 Arg Phe Gln Thr Glu Ile Cys Arg Ala Ser Glu Ser Gln Arg Glu Leu
      50                  55                  60

 acc acg ata tca gtt gct tcc aga aag caa tgg aca tcg tga              234
 Thr Thr Ile Ser Val Ala Ser Arg Lys Gln Trp Thr Ser 
  65                  70                  75





      <210> 220
      <211> 510
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(510)

      <400> 220
  atg gtc att gtt ggc ctg gca gcg ggg gtc ttg tta gtg ggt cct ggt      48
  Met Val Ile Val Gly Leu Ala Ala Gly Val Leu Leu Val Gly Pro Gly
    1               5                  10                  15

 gat ggg ggt cta atc agt gag ggt gtg gtc agg gaa gac ctg atg tgt       96
 Asp Gly Gly Leu Ile Ser Glu Gly Val Val Arg Glu Asp Leu Met Cys
              20                  25                  30

 ggg gtc tgg tca gca gga acc tgg tca gtg ggg act gct gag cgc tgc      144
 Gly Val Trp Ser Ala Gly Thr Trp Ser Val Gly Thr Ala Glu Arg Cys
          35                  40                  45

 ttg gag aag cca ggt gca ttg cac gtt atc gag ggc cct ctg gac agc      192
 Leu Glu Lys Pro Gly Ala Leu His Val Ile Glu Gly Pro Leu Asp Ser
      50                  55                  60

 tgg gat ggc cca gtg atg ccc aat ggc ccg gtc aaa aat cat aaa gga      240
 Trp Asp Gly Pro Val Met Pro Asn Gly Pro Val Lys Asn His Lys Gly
  65                  70                  75                  80

 gaa cag caa gag gtc ccc agc aaa cat cca cag atg gcc ttg gaa atc      288
 Glu Gln Gln Glu Val Pro Ser Lys His Pro Gln Met Ala Leu Glu Ile
                  85                  90                  95

 tgc ctg tgc ttg gac ttc ctg tac tac cca ttc ctg agg ggc gat gct      336
 Cys Leu Cys Leu Asp Phe Leu Tyr Tyr Pro Phe Leu Arg Gly Asp Ala
             100                 105                 110

 tct gca ggg cct gtg act tgg tgc aca act tca gac acc atc atc ttg      384
 Ser Ala Gly Pro Val Thr Trp Cys Thr Thr Ser Asp Thr Ile Ile Leu
         115                 120                 125

 cag cag cac cgc acc ctc act agc cag ggt gtt gat gac ttc ctc aag      432
 Gln Gln His Arg Thr Leu Thr Ser Gln Gly Val Asp Asp Phe Leu Lys
     130                 135                 140

 gcc aag gcc aca ttc aag gct tcg gac ttt att gat gcg ctt gtg ctg      480
 Ala Lys Ala Thr Phe Lys Ala Ser Asp Phe Ile Asp Ala Leu Val Leu
 145                 150                 155                 160

 agc aag ttc cta gaa gct tta att gaa tga                              510
 Ser Lys Phe Leu Glu Ala Leu Ile Glu 
                 165





      <210> 221
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 221
  atg ggg cac gtg gct cga tcc atg tgg aga agg tcc ttg ctt ctt act      48
  Met Gly His Val Ala Arg Ser Met Trp Arg Arg Ser Leu Leu Leu Thr
    1               5                  10                  15

 tct gct gaa tct cag ggg ctg acc caa gat gaa aag ccc cat ttc atc       96
 Ser Ala Glu Ser Gln Gly Leu Thr Gln Asp Glu Lys Pro His Phe Ile
              20                  25                  30

 aaa ggc tcc tca gtg gtc tca cac gac cct cca gag ggc tgg gga gta      144
 Lys Gly Ser Ser Val Val Ser His Asp Pro Pro Glu Gly Trp Gly Val
          35                  40                  45

 gga atc tgg ctg ttg ctg cca cca aag ggt gga ttg tgg ggc acc agg      192
 Gly Ile Trp Leu Leu Leu Pro Pro Lys Gly Gly Leu Trp Gly Thr Arg
      50                  55                  60

 ctt atc tac cct aga aca caa gaa gga aca gtg tct gcc atg tgc aaa      240
 Leu Ile Tyr Pro Arg Thr Gln Glu Gly Thr Val Ser Ala Met Cys Lys
  65                  70                  75                  80

 atg ggg gga aat ccc cag gcc tct agc caa atg caa agc tca gat ata      288
 Met Gly Gly Asn Pro Gln Ala Ser Ser Gln Met Gln Ser Ser Asp Ile
                  85                  90                  95

 ggg gta aag tca ggc ttg ggt caa gaa ttg ttc tag                      324
 Gly Val Lys Ser Gly Leu Gly Gln Glu Leu Phe 
             100                 105





      <210> 222
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 222
  atg aag cca gta agt cgt cgc acg ctg gac tgg att tat tca gtg ttg      48
  Met Lys Pro Val Ser Arg Arg Thr Leu Asp Trp Ile Tyr Ser Val Leu
    1               5                  10                  15

 ctg ctt gcc atc gtt tta atc tcc tgg ggc tgc atc atc tat gct tcg       96
 Leu Leu Ala Ile Val Leu Ile Ser Trp Gly Cys Ile Ile Tyr Ala Ser
              20                  25                  30

 atg gtg tct gca aga cga cag cta agg aag aaa tac cca gac aaa atc      144
 Met Val Ser Ala Arg Arg Gln Leu Arg Lys Lys Tyr Pro Asp Lys Ile
          35                  40                  45

 ttt ggg acg aat gaa aat ttg taa                                      168
 Phe Gly Thr Asn Glu Asn Leu 
      50                  55





      <210> 223
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 223
  atg tgg atg gat gct ggc tgg ttg ctg ggc agc tgg ctg acc tgg gct      48
  Met Trp Met Asp Ala Gly Trp Leu Leu Gly Ser Trp Leu Thr Trp Ala
    1               5                  10                  15

 ggg tcc caa gga cca gtc ttc aga gca cga gcc att caa atc tgt cca       96
 Gly Ser Gln Gly Pro Val Phe Arg Ala Arg Ala Ile Gln Ile Cys Pro
              20                  25                  30

 tca gca aaa ctg cgc ttc act gtg gaa gag cct cta ggc aag aac aat      144
 Ser Ala Lys Leu Arg Phe Thr Val Glu Glu Pro Leu Gly Lys Asn Asn
          35                  40                  45

 gat atc ata ctt cta agt gtc aag ccc cta ctg tgc agt ttc tgt gat      192
 Asp Ile Ile Leu Leu Ser Val Lys Pro Leu Leu Cys Ser Phe Cys Asp
      50                  55                  60

 tca aaa ggg aag act gat gag tca aat gag gcc cag aga ggg caa gaa      240
 Ser Lys Gly Lys Thr Asp Glu Ser Asn Glu Ala Gln Arg Gly Gln Glu
  65                  70                  75                  80

 gct gtc aca cag gaa gac cac aca gga aga cca ggt ggt aag caa atc      288
 Ala Val Thr Gln Glu Asp His Thr Gly Arg Pro Gly Gly Lys Gln Ile
                  85                  90                  95

 tcc cag gac cgt aga gcc aac aag tca cat atg gga aag ggc tct gag      336
 Ser Gln Asp Arg Arg Ala Asn Lys Ser His Met Gly Lys Gly Ser Glu
             100                 105                 110

 aaa tct tac aac ata tgc aac acc aag gat ctt gtc ctc tat gtc tga      384
 Lys Ser Tyr Asn Ile Cys Asn Thr Lys Asp Leu Val Leu Tyr Val 
         115                 120                 125





      <210> 224
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 224
  atg ctt gtc cca gtc ctg atc cta agc ccc tgc ctc gtt ggc att gag      48
  Met Leu Val Pro Val Leu Ile Leu Ser Pro Cys Leu Val Gly Ile Glu
    1               5                  10                  15

 cct tgg gaa gtg tca ccc cac acc aac tcc acc agc tcc tac gaa agc       96
 Pro Trp Glu Val Ser Pro His Thr Asn Ser Thr Ser Ser Tyr Glu Ser
              20                  25                  30

 acc ccc aaa tca tac cct cta ggc acc gca gca aaa gca gct tca ggg      144
 Thr Pro Lys Ser Tyr Pro Leu Gly Thr Ala Ala Lys Ala Ala Ser Gly
          35                  40                  45

 caa tcc ccc agc aca acc tca ccc ctt cct gag act gct ccc tcc acc      192
 Gln Ser Pro Ser Thr Thr Ser Pro Leu Pro Glu Thr Ala Pro Ser Thr
      50                  55                  60

 ctt cat gaa cgg ggg ctg gaa aat gtg gtc tgc tct gat aag gat ttg      240
 Leu His Glu Arg Gly Leu Glu Asn Val Val Cys Ser Asp Lys Asp Leu
  65                  70                  75                  80

 cgt cag gct act ggc tac tca gca gcc gag aag agc aag cct cca ggc      288
 Arg Gln Ala Thr Gly Tyr Ser Ala Ala Glu Lys Ser Lys Pro Pro Gly
                  85                  90                  95

 ctc tgc acg cgt gcc ttc tgc ccg gaa gcc atc cct gat gcc caa gac      336
 Leu Cys Thr Arg Ala Phe Cys Pro Glu Ala Ile Pro Asp Ala Gln Asp
             100                 105                 110

 tgg gtt aag tgc cag ccc ctg ggc tcc ctc agt gcc ttg aat ttc tga      384
 Trp Val Lys Cys Gln Pro Leu Gly Ser Leu Ser Ala Leu Asn Phe 
         115                 120                 125





      <210> 225
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 225
  atg atg cat gct aag ttc att ttt gtg gcc ata gaa aca ttc atg gat      48
  Met Met His Ala Lys Phe Ile Phe Val Ala Ile Glu Thr Phe Met Asp
    1               5                  10                  15

 gtt gct ttt gct gtc ttc ttg cct cct ggt cct ctt ggg att cca gtg       96
 Val Ala Phe Ala Val Phe Leu Pro Pro Gly Pro Leu Gly Ile Pro Val
              20                  25                  30

 caa tgc atc aaa cca tac cat ggc atg gct ggg acc caa tgc agt act      144
 Gln Cys Ile Lys Pro Tyr His Gly Met Ala Gly Thr Gln Cys Ser Thr
          35                  40                  45

 gga aat gaa gaa tgt gag cct gta gga ccc gca gcc ccg gac aat gca      192
 Gly Asn Glu Glu Cys Glu Pro Val Gly Pro Ala Ala Pro Asp Asn Ala
      50                  55                  60

 gct tcc tcg gac aac aca gat aat ctg ttc ctt gct atg ctg tct gtt      240
 Ala Ser Ser Asp Asn Thr Asp Asn Leu Phe Leu Ala Met Leu Ser Val
  65                  70                  75                  80

 gta cat tgc aac tct tgt aag gat gca aag ctg gaa cac aag ctg taa      288
 Val His Cys Asn Ser Cys Lys Asp Ala Lys Leu Glu His Lys Leu 
                  85                  90                  95





      <210> 226
      <211> 828
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(828)

      <400> 226
  atg gct ttt ctg acc aat gta ctt gct ttt cat ttc att ttt gtt ttt      48
  Met Ala Phe Leu Thr Asn Val Leu Ala Phe His Phe Ile Phe Val Phe
    1               5                  10                  15

 gtt aaa gag ggt aag cca gag aaa ttt tca ttt ggt ctt ctg gat ctt       96
 Val Lys Glu Gly Lys Pro Glu Lys Phe Ser Phe Gly Leu Leu Asp Leu
              20                  25                  30

 cct ttt cgt gtt gga gtt cca ttt aat atc cct ctg gag ttt cag gat      144
 Pro Phe Arg Val Gly Val Pro Phe Asn Ile Pro Leu Glu Phe Gln Asp
          35                  40                  45

 gaa ttt ggt cat acc agt caa cta gta act gat att cag cca gtt ctt      192
 Glu Phe Gly His Thr Ser Gln Leu Val Thr Asp Ile Gln Pro Val Leu
      50                  55                  60

 gaa gca agt ggt tta tct tta cat tat gaa gaa ata acc aat gga cca      240
 Glu Ala Ser Gly Leu Ser Leu His Tyr Glu Glu Ile Thr Asn Gly Pro
  65                  70                  75                  80

 aat tgt gta att cga ggt gtt aca gcc aag ggc cct gta aac tct tgt      288
 Asn Cys Val Ile Arg Gly Val Thr Ala Lys Gly Pro Val Asn Ser Cys
                  85                  90                  95

 caa ggc aag gtg gaa gtt tta gat gaa tca gac aac ata aca gca caa      336
 Gln Gly Lys Val Glu Val Leu Asp Glu Ser Asp Asn Ile Thr Ala Gln
             100                 105                 110

 cca aaa ttg att gtt cat tgt aag agt tgt aaa gat gtg gca cct gtg      384
 Pro Lys Leu Ile Val His Cys Lys Ser Cys Lys Asp Val Ala Pro Val
         115                 120                 125

 gag aag act att aag ttg ctt ccc agt agc cat gtt gca aga cta caa      432
 Glu Lys Thr Ile Lys Leu Leu Pro Ser Ser His Val Ala Arg Leu Gln
     130                 135                 140

 ata ttc agt gta gaa gga caa aag gca att cag atc aaa cat cag gat      480
 Ile Phe Ser Val Glu Gly Gln Lys Ala Ile Gln Ile Lys His Gln Asp
 145                 150                 155                 160

 gag gtt aat tgg ata gcg ggt gat att atg cat aat ctt att ttt caa      528
 Glu Val Asn Trp Ile Ala Gly Asp Ile Met His Asn Leu Ile Phe Gln
                 165                 170                 175

 atg tat gat gaa gga gaa aga gaa atc aat ata aca tca gct tta gca      576
 Met Tyr Asp Glu Gly Glu Arg Glu Ile Asn Ile Thr Ser Ala Leu Ala
             180                 185                 190

 gaa aaa att aaa gtt aat tgg act cct gag att aac aaa gaa cac ttg      624
 Glu Lys Ile Lys Val Asn Trp Thr Pro Glu Ile Asn Lys Glu His Leu
         195                 200                 205

 cta cag ggt ctg ctt cct gat gtg caa gta cca aca tct gta aaa gat      672
 Leu Gln Gly Leu Leu Pro Asp Val Gln Val Pro Thr Ser Val Lys Asp
     210                 215                 220

 atg cgc tat tgc cag gtt tca ttc caa gat gat cat gtg tct ttg gaa      720
 Met Arg Tyr Cys Gln Val Ser Phe Gln Asp Asp His Val Ser Leu Glu
 225                 230                 235                 240

 agt gcg ttt aca gta agt tat aat aat tac aga tca gta cgg aaa tca      768
 Ser Ala Phe Thr Val Ser Tyr Asn Asn Tyr Arg Ser Val Arg Lys Ser
                 245                 250                 255

 gat tca agc att ttc acc aag ttc ttt atc ttc ttt gtc aat tgc tgg      816
 Asp Ser Ser Ile Phe Thr Lys Phe Phe Ile Phe Phe Val Asn Cys Trp
             260                 265                 270

 ggt tgg act tga                                                      828
 Gly Trp Thr 
         275





      <210> 227
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 227
  atg ctg gca tcc ccc ctg tgg ctc caa gcg ctg agc ttg gcg gcg ggg      48
  Met Leu Ala Ser Pro Leu Trp Leu Gln Ala Leu Ser Leu Ala Ala Gly
    1               5                  10                  15

 acc tgg cgg ccc cgg ctc ggc tcg gga cag gca gga aac tca gaa atg       96
 Thr Trp Arg Pro Arg Leu Gly Ser Gly Gln Ala Gly Asn Ser Glu Met
              20                  25                  30

 aga gca ggg ttc ttg cct ggt gca ggc agc cag gtc cga gca cag ctg      144
 Arg Ala Gly Phe Leu Pro Gly Ala Gly Ser Gln Val Arg Ala Gln Leu
          35                  40                  45

 cag gac aga tta cca aag acc act gaa acc aaa gga gcc ctc tgg cca      192
 Gln Asp Arg Leu Pro Lys Thr Thr Glu Thr Lys Gly Ala Leu Trp Pro
      50                  55                  60

 cac act gag cta tgc ggg atg tgg agc atc gcc cca ggt gca gag aac      240
 His Thr Glu Leu Cys Gly Met Trp Ser Ile Ala Pro Gly Ala Glu Asn
  65                  70                  75                  80

 cag gag cta cag ata gat tct ccc ctt ctg ggg cag ttg agc aat cag      288
 Gln Glu Leu Gln Ile Asp Ser Pro Leu Leu Gly Gln Leu Ser Asn Gln
                  85                  90                  95

 gtg tgg agg gaa gat ggc tat ggt aag gcc ttt agg tta cgg act ctt      336
 Val Trp Arg Glu Asp Gly Tyr Gly Lys Ala Phe Arg Leu Arg Thr Leu
             100                 105                 110

 agc tcc atg ggg atc act gaa gag gcc aat gag aat gtt ctg att tga      384
 Ser Ser Met Gly Ile Thr Glu Glu Ala Asn Glu Asn Val Leu Ile 
         115                 120                 125





      <210> 228
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 228
  atg aag aaa ggg atg ttt tgc ttt aga cgt gaa ttc ggt ttc ctt ttt      48
  Met Lys Lys Gly Met Phe Cys Phe Arg Arg Glu Phe Gly Phe Leu Phe
    1               5                  10                  15

 act ttc ttg tac atg cag atc aca tac tca gcc ata gtg gga att tgc       96
 Thr Phe Leu Tyr Met Gln Ile Thr Tyr Ser Ala Ile Val Gly Ile Cys
              20                  25                  30

 ctt gac tta tcc tct gct tac tgc aac tct gct agc agg ata aat cct      144
 Leu Asp Leu Ser Ser Ala Tyr Cys Asn Ser Ala Ser Arg Ile Asn Pro
          35                  40                  45

 ggt atc acc agg atg act gca gtt gac cag tgg caa ctg aaa cca tgg      192
 Gly Ile Thr Arg Met Thr Ala Val Asp Gln Trp Gln Leu Lys Pro Trp
      50                  55                  60

 ata aag ggg gac tcc tta ctg cat aac tat gag gaa tcc tct gct aag      240
 Ile Lys Gly Asp Ser Leu Leu His Asn Tyr Glu Glu Ser Ser Ala Lys
  65                  70                  75                  80

 agg ttc ttc tct atg cct ctg ttc tgg aag agg aac ctc atc ccc cga      288
 Arg Phe Phe Ser Met Pro Leu Phe Trp Lys Arg Asn Leu Ile Pro Arg
                  85                  90                  95

 gat cac aac ttc agg agg gca aac aaa gag gag gta gga aag aag aag      336
 Asp His Asn Phe Arg Arg Ala Asn Lys Glu Glu Val Gly Lys Lys Lys
             100                 105                 110

 aca tgc ctg gac agc cac gaa ggc cag atc aac acc ccc aat ggc tct      384
 Thr Cys Leu Asp Ser His Glu Gly Gln Ile Asn Thr Pro Asn Gly Ser
         115                 120                 125

 cgc acc taa                                                          393
 Arg Thr 
     130





      <210> 229
      <211> 591
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(591)

      <400> 229
  atg cga acc cag gtc ccg gga gtt ccg ggc tgg gtc ttg ctt gtt ttc      48
  Met Arg Thr Gln Val Pro Gly Val Pro Gly Trp Val Leu Leu Val Phe
    1               5                  10                  15

 act gcg tta ggc ctg acg cat tac tcc gtc tcc caa gaa aga atc cgg       96
 Thr Ala Leu Gly Leu Thr His Tyr Ser Val Ser Gln Glu Arg Ile Arg
              20                  25                  30

 ccc gaa att tgc gtg ccc cgg gga gga ggc gag agg agg cga aag gaa      144
 Pro Glu Ile Cys Val Pro Arg Gly Gly Gly Glu Arg Arg Arg Lys Glu
          35                  40                  45

 gga aac tcc agc acg ggt ttt cgg gcc ggc tcc tgg ggc gct caa gcg      192
 Gly Asn Ser Ser Thr Gly Phe Arg Ala Gly Ser Trp Gly Ala Gln Ala
      50                  55                  60

 ggt tgc ggc ggc cag tcc cgg gcg gcg act ccg ggc cgg att ttg cgc      240
 Gly Cys Gly Gly Gln Ser Arg Ala Ala Thr Pro Gly Arg Ile Leu Arg
  65                  70                  75                  80

 gcg ccc acc gcc ccc ctc ccg gag cgg ctt ccc ccc agc ccc ggc tcc      288
 Ala Pro Thr Ala Pro Leu Pro Glu Arg Leu Pro Pro Ser Pro Gly Ser
                  85                  90                  95

 ggg aga tgt gcc ggg cgg ggg gcc cgg gtt cgc cga gcc gca gga gag      336
 Gly Arg Cys Ala Gly Arg Gly Ala Arg Val Arg Arg Ala Ala Gly Glu
             100                 105                 110

 aca cgc tgg gcc gac ccc aga gcg gcg ctg gac aga act gac ttg ccc      384
 Thr Arg Trp Ala Asp Pro Arg Ala Ala Leu Asp Arg Thr Asp Leu Pro
         115                 120                 125

 att aat tac aga gat gaa aaa tca tct gga att cgg aaa agg gaa cta      432
 Ile Asn Tyr Arg Asp Glu Lys Ser Ser Gly Ile Arg Lys Arg Glu Leu
     130                 135                 140

 att cca tgg ctg gca gcg atc gca ccc gtg cac gga gcc aca tac atg      480
 Ile Pro Trp Leu Ala Ala Ile Ala Pro Val His Gly Ala Thr Tyr Met
 145                 150                 155                 160

 tgc gac ata cgt gtg cgc tca cat ctc acg acc cgc ttc ctc gat gca      528
 Cys Asp Ile Arg Val Arg Ser His Leu Thr Thr Arg Phe Leu Asp Ala
                 165                 170                 175

 gct gcc acc gtt att caa aca tac agg cac agt cca gcc cca ggg cct      576
 Ala Ala Thr Val Ile Gln Thr Tyr Arg His Ser Pro Ala Pro Gly Pro
             180                 185                 190

 ttg cac ggg ctg tga                                                  591
 Leu His Gly Leu 
         195





      <210> 230
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 230
  atg ccg ctt ccc ccg gac ttc gcc tgt ggt ttc gtc atc ctg gtc ggc      48
  Met Pro Leu Pro Pro Asp Phe Ala Cys Gly Phe Val Ile Leu Val Gly
    1               5                  10                  15

 cct ttg cga ctc ctg gca gcc aga gat gtt cct gtc gac ccc gtg gag       96
 Pro Leu Arg Leu Leu Ala Ala Arg Asp Val Pro Val Asp Pro Val Glu
              20                  25                  30

 aga gaa gag gcg tgg aaa ggt aca acc atc ttc ttg gac gtg ggt ctg      144
 Arg Glu Glu Ala Trp Lys Gly Thr Thr Ile Phe Leu Asp Val Gly Leu
          35                  40                  45

 ctc ctc tcc tgc cgg aca atg tgc tac cgt ggg gca ttt gtc ctg ggc      192
 Leu Leu Ser Cys Arg Thr Met Cys Tyr Arg Gly Ala Phe Val Leu Gly
      50                  55                  60

 tgg agt gtg gtc ctc ttg atc cta gaa aag agg acg ctc atg atg ggg      240
 Trp Ser Val Val Leu Leu Ile Leu Glu Lys Arg Thr Leu Met Met Gly
  65                  70                  75                  80

 atg aga ctt cca ttg ctc ccg gcc gac gca tcc cct cac gtg atc gag      288
 Met Arg Leu Pro Leu Leu Pro Ala Asp Ala Ser Pro His Val Ile Glu
                  85                  90                  95

 gat ttc gca aac cca aag tgg aac cgc cgt gaa aac gat gga cag ctg      336
 Asp Phe Ala Asn Pro Lys Trp Asn Arg Arg Glu Asn Asp Gly Gln Leu
             100                 105                 110

 gac agg acc cag gga gag acg cag aaa gaa acc cac caa aga ccg gca      384
 Asp Arg Thr Gln Gly Glu Thr Gln Lys Glu Thr His Gln Arg Pro Ala
         115                 120                 125

 gac aag caa gaa atc cct ttc tga                                      408
 Asp Lys Gln Glu Ile Pro Phe 
     130                 135





      <210> 231
      <211> 315
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(315)

      <400> 231
  atg agg ggg gtt ctg cga gtg ttg gga aat ctg caa atg gct gcg gca      48
  Met Arg Gly Val Leu Arg Val Leu Gly Asn Leu Gln Met Ala Ala Ala
    1               5                  10                  15

 gga agg aac tgg caa tgc cag ggc act tcc tct gag agg acg gca gag       96
 Gly Arg Asn Trp Gln Cys Gln Gly Thr Ser Ser Glu Arg Thr Ala Glu
              20                  25                  30

 ggc gca gat tta gct tct gtc ctg cga atg aag cac gca gta caa ggt      144
 Gly Ala Asp Leu Ala Ser Val Leu Arg Met Lys His Ala Val Gln Gly
          35                  40                  45

 tcc aaa ctg caa gtc aac agc aag cac gaa gca gcc aca ctg gaa atg      192
 Ser Lys Leu Gln Val Asn Ser Lys His Glu Ala Ala Thr Leu Glu Met
      50                  55                  60

 ggg tgc ctc cat cgc ctg ggg ctg tgg gct gcc atc ctc tgc caa gcg      240
 Gly Cys Leu His Arg Leu Gly Leu Trp Ala Ala Ile Leu Cys Gln Ala
  65                  70                  75                  80

 gat gct ctg cca cca gct cca ctg aca tgg gca agc cac ttc ctg tcg      288
 Asp Ala Leu Pro Pro Ala Pro Leu Thr Trp Ala Ser His Phe Leu Ser
                  85                  90                  95

 ccc tgg ccc cca gct cct cat gtg taa                                  315
 Pro Trp Pro Pro Ala Pro His Val 
             100





      <210> 232
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 232
  atg tcc ccg ctg cgc ccg ctg ctg ctg gcc ctg gcc ctt gcc tcc gtg      48
  Met Ser Pro Leu Arg Pro Leu Leu Leu Ala Leu Ala Leu Ala Ser Val
    1               5                  10                  15

 cct tgc gcc cag ggc gcc tgc ccc gcc tcc gcc gac ctc aag cac tcg       96
 Pro Cys Ala Gln Gly Ala Cys Pro Ala Ser Ala Asp Leu Lys His Ser
              20                  25                  30

 gac ggg acg cgc act tgc gcc aag ctc tat gac aag agc gac ccc tac      144
 Asp Gly Thr Arg Thr Cys Ala Lys Leu Tyr Asp Lys Ser Asp Pro Tyr
          35                  40                  45

 tat gag aac tgc tgc ggg ggc gcc gag ctg tcg ctg gag tcg ggc gca      192
 Tyr Glu Asn Cys Cys Gly Gly Ala Glu Leu Ser Leu Glu Ser Gly Ala
      50                  55                  60

 gac ctg ccc tac ctg ccc tcc aac tgg gcc aac acc gcc tcc tca ctt      240
 Asp Leu Pro Tyr Leu Pro Ser Asn Trp Ala Asn Thr Ala Ser Ser Leu
  65                  70                  75                  80

 gtg gtg gcc ccg cgc tgc gag ctc acc gtg tgg tcc cgg caa ggc aag      288
 Val Val Ala Pro Arg Cys Glu Leu Thr Val Trp Ser Arg Gln Gly Lys
                  85                  90                  95

 gcg ggc aag acg cac aag ttc tct gcc ggc acc tac ccg cgc ctg gag      336
 Ala Gly Lys Thr His Lys Phe Ser Ala Gly Thr Tyr Pro Arg Leu Glu
             100                 105                 110

 gag tac cgc cgg ggc atc tta gga gac tgg tcc aac gct atc tcc gcg      384
 Glu Tyr Arg Arg Gly Ile Leu Gly Asp Trp Ser Asn Ala Ile Ser Ala
         115                 120                 125

 ctc tac tgc agg tgc ccg gcc gcc caa agc tcc gag ccc acc cca ggc      432
 Leu Tyr Cys Arg Cys Pro Ala Ala Gln Ser Ser Glu Pro Thr Pro Gly
     130                 135                 140

 cca ggc ccc agc tcc gca taa                                          453
 Pro Gly Pro Ser Ser Ala 
 145                 150





      <210> 233
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 233
  atg gcc agc ttc tgg gtg tgg gca cag tgc cac atc ttc cat cac ttt      48
  Met Ala Ser Phe Trp Val Trp Ala Gln Cys His Ile Phe His His Phe
    1               5                  10                  15

 ctg atg tat ccc acc agc act gaa gag aca gcc tgg aga gag tgc aag       96
 Leu Met Tyr Pro Thr Ser Thr Glu Glu Thr Ala Trp Arg Glu Cys Lys
              20                  25                  30

 agg aag gct gag aag gat gag ata gcc atc cac ttc acc aga gat gcc      144
 Arg Lys Ala Glu Lys Asp Glu Ile Ala Ile His Phe Thr Arg Asp Ala
          35                  40                  45

 ttc aag aac atc agt aag ctc ctt gcc aat cag tcc agg aag gac ctg      192
 Phe Lys Asn Ile Ser Lys Leu Leu Ala Asn Gln Ser Arg Lys Asp Leu
      50                  55                  60

 gac cca gcc agg gac ctg tta gtg ctg tct cag gga cac cag acc aac      240
 Asp Pro Ala Arg Asp Leu Leu Val Leu Ser Gln Gly His Gln Thr Asn
  65                  70                  75                  80

 atc ctg gac atc atc ctc ata cac aag gaa gct ctt acc aaa gtc acg      288
 Ile Leu Asp Ile Ile Leu Ile His Lys Glu Ala Leu Thr Lys Val Thr
                  85                  90                  95

 gag aac agg caa cat gtg gca gaa ggg aag aca gag gtg cag agg ctg      336
 Glu Asn Arg Gln His Val Ala Glu Gly Lys Thr Glu Val Gln Arg Leu
             100                 105                 110

 atg gtg tca tta tca cag gaa cag gat ttc ttt ggc cac ttt ggc tga      384
 Met Val Ser Leu Ser Gln Glu Gln Asp Phe Phe Gly His Phe Gly 
         115                 120                 125





      <210> 234
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 234
  atg aag att ttc ttc ttt gct ttc ttg atg aaa ctg tca atc ttc ata      48
  Met Lys Ile Phe Phe Phe Ala Phe Leu Met Lys Leu Ser Ile Phe Ile
    1               5                  10                  15

 atg gtg tta gca atc aca ggg atg tgc tgc gaa gcg gct tta aag gca       96
 Met Val Leu Ala Ile Thr Gly Met Cys Cys Glu Ala Ala Leu Lys Ala
              20                  25                  30

 tct gat aaa gag aaa acc tgt gct ctc ccg ttc ctg agc ccc tct tta      144
 Ser Asp Lys Glu Lys Thr Cys Ala Leu Pro Phe Leu Ser Pro Ser Leu
          35                  40                  45

 gag tca gtt acc agt gat aag gtt ggg cat tct gac ttg tac aga gta      192
 Glu Ser Val Thr Ser Asp Lys Val Gly His Ser Asp Leu Tyr Arg Val
      50                  55                  60

 caa gga att tga                                                      204
 Gln Gly Ile 
  65





      <210> 235
      <211> 426
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(426)

      <400> 235
  atg agg agg atc atc gtg gga ctc atc ttc ctt ata att tgg gct tgt      48
  Met Arg Arg Ile Ile Val Gly Leu Ile Phe Leu Ile Ile Trp Ala Cys
    1               5                  10                  15

 ata gta aaa act tcc act gat ttt ccc cac atg gag gac tgc tct cag       96
 Ile Val Lys Thr Ser Thr Asp Phe Pro His Met Glu Asp Cys Ser Gln
              20                  25                  30

 tgt ata cat cag gtt acc gag aga agc ata gcc ata ggg aat tgg caa      144
 Cys Ile His Gln Val Thr Glu Arg Ser Ile Ala Ile Gly Asn Trp Gln
          35                  40                  45

 gat gat gaa tgg ctc cct gag aga atc aca caa tat tat ggg cct gct      192
 Asp Asp Glu Trp Leu Pro Glu Arg Ile Thr Gln Tyr Tyr Gly Pro Ala
      50                  55                  60

 act tgg gca caa tac ggc tcg tgg gga tac tac aac ccc att tac atg      240
 Thr Trp Ala Gln Tyr Gly Ser Trp Gly Tyr Tyr Asn Pro Ile Tyr Met
  65                  70                  75                  80

 ctc aac caa atg ata tgg tta caa gct gtc tta gaa ata acc act aat      288
 Leu Asn Gln Met Ile Trp Leu Gln Ala Val Leu Glu Ile Thr Thr Asn
                  85                  90                  95

 aaa act ggc aga gcc ttg act att ctg gcc tgg caa gaa act cag atg      336
 Lys Thr Gly Arg Ala Leu Thr Ile Leu Ala Trp Gln Glu Thr Gln Met
             100                 105                 110

 aga aat cct acc tat caa gat aga ttg gct ctc gac tac tta cta gca      384
 Arg Asn Pro Thr Tyr Gln Asp Arg Leu Ala Leu Asp Tyr Leu Leu Ala
         115                 120                 125

 gct gaa gga ggg gtc tgt ggg aaa ttt aac ctt act aat tga              426
 Ala Glu Gly Gly Val Cys Gly Lys Phe Asn Leu Thr Asn 
     130                 135                 140





      <210> 236
      <211> 471
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(471)

      <400> 236
  atg cat tat ctt att tgt tct tca aaa tcc tct agc ccc atc acc aga      48
  Met His Tyr Leu Ile Cys Ser Ser Lys Ser Ser Ser Pro Ile Thr Arg
    1               5                  10                  15

 agg att tta tat tgc acg ctg atc ttg cct atg tat cac ctc gag cct       96
 Arg Ile Leu Tyr Cys Thr Leu Ile Leu Pro Met Tyr His Leu Glu Pro
              20                  25                  30

 ttc ttt tca tac atc ttc ctc aac cta cag ctc atg atc ttg cag gtc      144
 Phe Phe Ser Tyr Ile Phe Leu Asn Leu Gln Leu Met Ile Leu Gln Val
          35                  40                  45

 ctt cac ctt tac tgg ggt tat tac atc ttg aag atg ctc aac aga tgt      192
 Leu His Leu Tyr Trp Gly Tyr Tyr Ile Leu Lys Met Leu Asn Arg Cys
      50                  55                  60

 ata ttc atg aag agg tcc cag cac caa ccg cac cag cca cag gac tcc      240
 Ile Phe Met Lys Arg Ser Gln His Gln Pro His Gln Pro Gln Asp Ser
  65                  70                  75                  80

 tct tct cgg tgg tac aac cag cag ctt cca ggc cca gcc aca tat cca      288
 Ser Ser Arg Trp Tyr Asn Gln Gln Leu Pro Gly Pro Ala Thr Tyr Pro
                  85                  90                  95

 gag ctt ggg gat cag aca ttt atg acg gtt cgc ttg aac atg ccc tcc      336
 Glu Leu Gly Asp Gln Thr Phe Met Thr Val Arg Leu Asn Met Pro Ser
             100                 105                 110

 aga gtg gct gga ggt ggt tac agc acc cct ggt tct cag tgt tcc tcc      384
 Arg Val Ala Gly Gly Gly Tyr Ser Thr Pro Gly Ser Gln Cys Ser Ser
         115                 120                 125

 gca att atc cta caa cag aca tca cca ccc cat ggt gca gaa aca gac      432
 Ala Ile Ile Leu Gln Gln Thr Ser Pro Pro His Gly Ala Glu Thr Asp
     130                 135                 140

 act gac act atg ctt tat gta gac gct gca gaa ctc tga                  471
 Thr Asp Thr Met Leu Tyr Val Asp Ala Ala Glu Leu 
 145                 150                 155





      <210> 237
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 237
  atg tcc agc tgg gct gtt ggg gac ctt cca ggc ctg tta ctt gta tgc      48
  Met Ser Ser Trp Ala Val Gly Asp Leu Pro Gly Leu Leu Leu Val Cys
    1               5                  10                  15

 tgc ctg gtg aca cct ggt gga ttg cat ggg gac tgc cat ggc gcc tat       96
 Cys Leu Val Thr Pro Gly Gly Leu His Gly Asp Cys His Gly Ala Tyr
              20                  25                  30

 ggg gca cag tcc gac cct gac agc caa cag gct cag aag cct gat cta      144
 Gly Ala Gln Ser Asp Pro Asp Ser Gln Gln Ala Gln Lys Pro Asp Leu
          35                  40                  45

 gcg gtg gcc ggg aag aca gat acc ggc acc aaa ggg cac tga              186
 Ala Val Ala Gly Lys Thr Asp Thr Gly Thr Lys Gly His 
      50                  55                  60





      <210> 238
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 238
  atg agc aca tgt tta act gag caa caa aac ttc ttg aga att ctc aac      48
  Met Ser Thr Cys Leu Thr Glu Gln Gln Asn Phe Leu Arg Ile Leu Asn
    1               5                  10                  15

 caa cta tta ctt tcg tcg att ttc ctg ctc tta agt ttg acc ctt ttc       96
 Gln Leu Leu Leu Ser Ser Ile Phe Leu Leu Leu Ser Leu Thr Leu Phe
              20                  25                  30

 agt aac atg ata tgg gac caa agt atc gat gaa aca gtg tct aca aaa      144
 Ser Asn Met Ile Trp Asp Gln Ser Ile Asp Glu Thr Val Ser Thr Lys
          35                  40                  45

 ggg tac act tgc cag cag ttt tgc cat gac agt aca ccg aac aaa gga      192
 Gly Tyr Thr Cys Gln Gln Phe Cys His Asp Ser Thr Pro Asn Lys Gly
      50                  55                  60

 gac agg gtc act tat aac ctg aca cgg cca ccc tac tgc tgt gtc ccg      240
 Asp Arg Val Thr Tyr Asn Leu Thr Arg Pro Pro Tyr Cys Cys Val Pro
  65                  70                  75                  80

 ttt cct ttg gct gga acg gga cct cag att ctg tat ttg tcc cga ttg      288
 Phe Pro Leu Ala Gly Thr Gly Pro Gln Ile Leu Tyr Leu Ser Arg Leu
                  85                  90                  95

 gct agc aac tta gaa ctt ttg aaa aga ggc aaa ggc aga gga gaa caa      336
 Ala Ser Asn Leu Glu Leu Leu Lys Arg Gly Lys Gly Arg Gly Glu Gln
             100                 105                 110

 agg aag gag gaa gta act tgt gga atg gtg aga aag gta aaa aga cct      384
 Arg Lys Glu Glu Val Thr Cys Gly Met Val Arg Lys Val Lys Arg Pro
         115                 120                 125

 tca aat aag gaa gaa gaa cag gct ttg acc taa                          417
 Ser Asn Lys Glu Glu Glu Gln Ala Leu Thr 
     130                 135





      <210> 239
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 239
  atg tgc tgc tgg ccg ctg ctc ctg ctg tgg ggg ctg ctc ccc ggg acg      48
  Met Cys Cys Trp Pro Leu Leu Leu Leu Trp Gly Leu Leu Pro Gly Thr
    1               5                  10                  15

 gcg gcg ggg ggc tcg ggc cga acc tat ccg cac cgg acc ctc ctg gac       96
 Ala Ala Gly Gly Ser Gly Arg Thr Tyr Pro His Arg Thr Leu Leu Asp
              20                  25                  30

 tcg gag ggc aag tac tgg ctg ggc tgg agc cag cgg ggc agc cag atc      144
 Ser Glu Gly Lys Tyr Trp Leu Gly Trp Ser Gln Arg Gly Ser Gln Ile
          35                  40                  45

 gcc ttc cgc ctc cag gtg cgc act gca ggc tac gtg ggc ttc ggc ttc      192
 Ala Phe Arg Leu Gln Val Arg Thr Ala Gly Tyr Val Gly Phe Gly Phe
      50                  55                  60

 tcg ccc acc ggg gcc atg gcg tcc gcc gac atc gtc gtg ggc ggg gtg      240
 Ser Pro Thr Gly Ala Met Ala Ser Ala Asp Ile Val Val Gly Gly Val
  65                  70                  75                  80

 gcc cac ggg cgg ccc tac ctc cag acg ccc ccc cgc cta cac acc tgc      288
 Ala His Gly Arg Pro Tyr Leu Gln Thr Pro Pro Arg Leu His Thr Cys
                  85                  90                  95

 aat aca ccc cgc ttc atc cct gat ggg aag gga gaa gga cct agg ctt      336
 Asn Thr Pro Arg Phe Ile Pro Asp Gly Lys Gly Glu Gly Pro Arg Leu
             100                 105                 110

 tgg ctt tgg gga cct aat ggg aca gct ctc aga gga ggg aag gga cag      384
 Trp Leu Trp Gly Pro Asn Gly Thr Ala Leu Arg Gly Gly Lys Gly Gln
         115                 120                 125

 agc gct tta gta cgt cgc gga ctt gct gtc tag                          417
 Ser Ala Leu Val Arg Arg Gly Leu Ala Val 
     130                 135





      <210> 240
      <211> 654
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(654)

      <400> 240
  atg ggg aca cag acg ctg gcc atc ttc gga tct gct gtt gga tgc ctg      48
  Met Gly Thr Gln Thr Leu Ala Ile Phe Gly Ser Ala Val Gly Cys Leu
    1               5                  10                  15

 gca cag gcg ctg tgg gtg ggg tcg att tgg gga aaa ggt cac cag gag       96
 Ala Gln Ala Leu Trp Val Gly Ser Ile Trp Gly Lys Gly His Gln Glu
              20                  25                  30

 aaa ctg cac ctg ggg agc ccg tgg ctg gca ctg cct ggg gca gca ggg      144
 Lys Leu His Leu Gly Ser Pro Trp Leu Ala Leu Pro Gly Ala Ala Gly
          35                  40                  45

 gct gag tgc ccc ctc agc agg acc agc gag ccc tca gga agg cat gag      192
 Ala Glu Cys Pro Leu Ser Arg Thr Ser Glu Pro Ser Gly Arg His Glu
      50                  55                  60

 aac atg tgc tcc tgg aag cca cag aaa cat cca gga gat gga gac ctt      240
 Asn Met Cys Ser Trp Lys Pro Gln Lys His Pro Gly Asp Gly Asp Leu
  65                  70                  75                  80

 tgc aag cta agc agg cca ggt tac ttt gac ctt gag ggc aat gga ggg      288
 Cys Lys Leu Ser Arg Pro Gly Tyr Phe Asp Leu Glu Gly Asn Gly Gly
                  85                  90                  95

 gca gga gaa ttt tgc cca gca gtc cct cgt ggc tcc ctc cac acc act      336
 Ala Gly Glu Phe Cys Pro Ala Val Pro Arg Gly Ser Leu His Thr Thr
             100                 105                 110

 gac cct tac gcg tcc aag gtt gga gcc ctg gca ggc agt tcc tgc acc      384
 Asp Pro Tyr Ala Ser Lys Val Gly Ala Leu Ala Gly Ser Ser Cys Thr
         115                 120                 125

 tcc tgc cgt gtg gat gct ggc cgt tgc tgt ctg act cgc att ctt gga      432
 Ser Cys Arg Val Asp Ala Gly Arg Cys Cys Leu Thr Arg Ile Leu Gly
     130                 135                 140

 gac act gac cca ggc tcc tct cag cgc ttc cag cca gct gtt ggc ctg      480
 Asp Thr Asp Pro Gly Ser Ser Gln Arg Phe Gln Pro Ala Val Gly Leu
 145                 150                 155                 160

 gac ccc tgc atc ctt tcc agg ttc atc ttc cag gtg gcc cgg cgc tgc      528
 Asp Pro Cys Ile Leu Ser Arg Phe Ile Phe Gln Val Ala Arg Arg Cys
                 165                 170                 175

 tgg tca ggg aac cag aag gcc tat gag atc atc tgc cag acc atg cag      576
 Trp Ser Gly Asn Gln Lys Ala Tyr Glu Ile Ile Cys Gln Thr Met Gln
             180                 185                 190

 gag aac agc acc ttg gtg gtg aca ctg cct cac aag gtg gag gac gag      624
 Glu Asn Ser Thr Leu Val Val Thr Leu Pro His Lys Val Glu Asp Glu
         195                 200                 205

 cgg gtg ctc cag cag gcc ctg cag ctc tga                              654
 Arg Val Leu Gln Gln Ala Leu Gln Leu 
     210                 215





      <210> 241
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 241
  atg agg gaa ggg tgg tgt tgg cat ttc aag act gtc ttt gct atc ctc      48
  Met Arg Glu Gly Trp Cys Trp His Phe Lys Thr Val Phe Ala Ile Leu
    1               5                  10                  15

 ttc agt gcc tct gtc agc gat atg aag tta aaa cca ggt act gtg att       96
 Phe Ser Ala Ser Val Ser Asp Met Lys Leu Lys Pro Gly Thr Val Ile
              20                  25                  30

 gct cac cgg att ttt ggt tcg tat gaa gtt gcc aac ttt gaa gtt cct      144
 Ala His Arg Ile Phe Gly Ser Tyr Glu Val Ala Asn Phe Glu Val Pro
          35                  40                  45

 gtg gaa gca gga gta att ctg ttt cag tac ctg aaa agt tct tat cta      192
 Val Glu Ala Gly Val Ile Leu Phe Gln Tyr Leu Lys Ser Ser Tyr Leu
      50                  55                  60

 gga ggt ggt aag aat gga agt gaa gct aaa gtt gta act ggt aaa aca      240
 Gly Gly Gly Lys Asn Gly Ser Glu Ala Lys Val Val Thr Gly Lys Thr
  65                  70                  75                  80

 gca gca gtc act cct att agc cag gat aag gga atg ctt ggc cat tct      288
 Ala Ala Val Thr Pro Ile Ser Gln Asp Lys Gly Met Leu Gly His Ser
                  85                  90                  95

 tgt ggt tta gac aat att cat ggt ttt gtc tgt gtt cag atg gtc aca      336
 Cys Gly Leu Asp Asn Ile His Gly Phe Val Cys Val Gln Met Val Thr
             100                 105                 110

 gag tgg cca ttt ctg aga ctg gca ttc cat gga att gtt gat gtt taa      384
 Glu Trp Pro Phe Leu Arg Leu Ala Phe His Gly Ile Val Asp Val 
         115                 120                 125





      <210> 242
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 242
  atg atg cag ttt ttc ttg gtc act ctg tgg gcc aca gac ttg cag ctg      48
  Met Met Gln Phe Phe Leu Val Thr Leu Trp Ala Thr Asp Leu Gln Leu
    1               5                  10                  15

 cca att ccc cct aca agc att gct cgg gtc cag gcc cac tgt agg aga       96
 Pro Ile Pro Pro Thr Ser Ile Ala Arg Val Gln Ala His Cys Arg Arg
              20                  25                  30

 cac cct gac tac tcc ggt gca gat ctc aca gct acc atg act gtt tgt      144
 His Pro Asp Tyr Ser Gly Ala Asp Leu Thr Ala Thr Met Thr Val Cys
          35                  40                  45

 tca gcc ccc aca ttc tcc agg gtc cca att tct tgt ccc aca ttc aaa      192
 Ser Ala Pro Thr Phe Ser Arg Val Pro Ile Ser Cys Pro Thr Phe Lys
      50                  55                  60

 aag aat gag gtt atg ctg cca gcc agt ggg gtc cac tca ctt atg cat      240
 Lys Asn Glu Val Met Leu Pro Ala Ser Gly Val His Ser Leu Met His
  65                  70                  75                  80

 tat ctc ata aag gat act gaa gcc cat tga                              270
 Tyr Leu Ile Lys Asp Thr Glu Ala His 
                  85





      <210> 243
      <211> 282
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(282)

      <400> 243
  atg gcg ctg cgc tcg ctc atg ttt ctc gcc agg ttt gct cat cag cca      48
  Met Ala Leu Arg Ser Leu Met Phe Leu Ala Arg Phe Ala His Gln Pro
    1               5                  10                  15

 aac aca agc caa act ctg ata gtc agc atc cag cct ctg gaa gat aca       96
 Asn Thr Ser Gln Thr Leu Ile Val Ser Ile Gln Pro Leu Glu Asp Thr
              20                  25                  30

 gaa cat ctg aca ttc atg ctt atc aag agc cct caa gct cct gaa gaa      144
 Glu His Leu Thr Phe Met Leu Ile Lys Ser Pro Gln Ala Pro Glu Glu
          35                  40                  45

 ctt tct gag cac tta agc atc agc tac agc tgg gat cag ttt ggc aag      192
 Leu Ser Glu His Leu Ser Ile Ser Tyr Ser Trp Asp Gln Phe Gly Lys
      50                  55                  60

 aca cat gca ttg cta tct ttc tgc aga cac aaa acc cca gct ctt gca      240
 Thr His Ala Leu Leu Ser Phe Cys Arg His Lys Thr Pro Ala Leu Ala
  65                  70                  75                  80

 aag cct caa aga ccc cag gaa tac tgc aca tgt tat gag tga              282
 Lys Pro Gln Arg Pro Gln Glu Tyr Cys Thr Cys Tyr Glu 
                  85                  90





      <210> 244
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 244
  atg tta ccg tcc aaa cta cgg cag ccc ttt acc ctc ctc atc acc aaa      48
  Met Leu Pro Ser Lys Leu Arg Gln Pro Phe Thr Leu Leu Ile Thr Lys
    1               5                  10                  15

 cta cag cag ccc ttt acc ctc ctc atc atg act gga gga gct cag cat       96
 Leu Gln Gln Pro Phe Thr Leu Leu Ile Met Thr Gly Gly Ala Gln His
              20                  25                  30

 gct ctc aag ccg cct tcc atc tgt tct agg cat ccc acg gtg gct tct      144
 Ala Leu Lys Pro Pro Ser Ile Cys Ser Arg His Pro Thr Val Ala Ser
          35                  40                  45

 cca gag agc tca gaa ata tgt ctg ctc ctg ttc cca ttt tcc tgc tct      192
 Pro Glu Ser Ser Glu Ile Cys Leu Leu Leu Phe Pro Phe Ser Cys Ser
      50                  55                  60

 ttc ctc cag gaa cct cga cgt agc ctg ttc cca atg ccc tct gtg gaa      240
 Phe Leu Gln Glu Pro Arg Arg Ser Leu Phe Pro Met Pro Ser Val Glu
  65                  70                  75                  80

 tca gcc aga tgt gat cta acg tcc ttg aac aca ttt att aca atc cat      288
 Ser Ala Arg Cys Asp Leu Thr Ser Leu Asn Thr Phe Ile Thr Ile His
                  85                  90                  95

 cat cta cat ggc aac agt cag ggc cat gct cat aaa cca gaa ctg gtg      336
 His Leu His Gly Asn Ser Gln Gly His Ala His Lys Pro Glu Leu Val
             100                 105                 110

 cta gat ctg gcc cct gag cag cgt gct ctg gca acg aat tac tgc tcc      384
 Leu Asp Leu Ala Pro Glu Gln Arg Ala Leu Ala Thr Asn Tyr Cys Ser
         115                 120                 125

 ttt atg ttg gag ctt tct cac cga aca acc gac atg gtg ttc act ctg      432
 Phe Met Leu Glu Leu Ser His Arg Thr Thr Asp Met Val Phe Thr Leu
     130                 135                 140

 aat cct tgg ccc cag aca cct aca att tga                              462
 Asn Pro Trp Pro Gln Thr Pro Thr Ile 
 145                 150





      <210> 245
      <211> 216
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(216)

      <400> 245
  atg gcg ctc ctg ctg tgc ttc gtg ctc ctg tgc gga gta gtg gcc ttc      48
  Met Ala Leu Leu Leu Cys Phe Val Leu Leu Cys Gly Val Val Ala Phe
    1               5                  10                  15

 gtg tcg gtt ctc tcc agc gtt acc cga ttt caa aaa cct tgg gcg gcg       96
 Val Ser Val Leu Ser Ser Val Thr Arg Phe Gln Lys Pro Trp Ala Ala
              20                  25                  30

 agt ttt cag gtg tcg agt cgc cca ggc ggg gag gct gaa ttg caa acg      144
 Ser Phe Gln Val Ser Ser Arg Pro Gly Gly Glu Ala Glu Leu Gln Thr
          35                  40                  45

 cca tta ttc aat gga cat gga gct gcc cgg tgc ctc gga tcg gcc agg      192
 Pro Leu Phe Asn Gly His Gly Ala Ala Arg Cys Leu Gly Ser Ala Arg
      50                  55                  60

 cta cct cta gga aag agg cgc tga                                      216
 Leu Pro Leu Gly Lys Arg Arg 
  65                  70





      <210> 246
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 246
  atg gcc ctg ggc aag gtt ctg gcc atg gca ctg gtt ttg gcc ttg gcc      48
  Met Ala Leu Gly Lys Val Leu Ala Met Ala Leu Val Leu Ala Leu Ala
    1               5                  10                  15

 gtg ctg ggg tcg ctg tcc cct ggg gcc cgg gcg ggg gac tgc aag ggg       96
 Val Leu Gly Ser Leu Ser Pro Gly Ala Arg Ala Gly Asp Cys Lys Gly
              20                  25                  30

 cag cgg cag gtg ctg cgg gag gcg cca ggc ttc gtg acg gat ggt gcg      144
 Gln Arg Gln Val Leu Arg Glu Ala Pro Gly Phe Val Thr Asp Gly Ala
          35                  40                  45

 ggc aac tac agc gtc aat ggc aac tgc gag tgg ctc atc gag gaa ccc      192
 Gly Asn Tyr Ser Val Asn Gly Asn Cys Glu Trp Leu Ile Glu Glu Pro
      50                  55                  60

 tgc ccc agt ggc tct ttc tct gtg aag aca tgt ggc tta acc tgg ggt      240
 Cys Pro Ser Gly Ser Phe Ser Val Lys Thr Cys Gly Leu Thr Trp Gly
  65                  70                  75                  80

 ata gct gag atc aga ggc atc tgt acg agg gag cag aag ggc att cca      288
 Ile Ala Glu Ile Arg Gly Ile Cys Thr Arg Glu Gln Lys Gly Ile Pro
                  85                  90                  95

 ggc aag aat agc tgt gca aag gcg ggg aag cgg gag agt gat gct ttt      336
 Gly Lys Asn Ser Cys Ala Lys Ala Gly Lys Arg Glu Ser Asp Ala Phe
             100                 105                 110

 gaa gaa cta gaa atc cag tgt gtt aaa aca tag                          369
 Glu Glu Leu Glu Ile Gln Cys Val Lys Thr 
         115                 120





      <210> 247
      <211> 1098
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1098)

      <400> 247
  atg gtg gct tgc ttt tta caa att ata tca ttc tac tat gtc ttc ttt      48
  Met Val Ala Cys Phe Leu Gln Ile Ile Ser Phe Tyr Tyr Val Phe Phe
    1               5                  10                  15

 ttt tac tcc act cag att cga aat cag agc aaa gcc tct ggg tct ggg       96
 Phe Tyr Ser Thr Gln Ile Arg Asn Gln Ser Lys Ala Ser Gly Ser Gly
              20                  25                  30

 ctc tgt gag gga gat gaa gtg gtt tcc atc aat ggc aac cct tgt gca      144
 Leu Cys Glu Gly Asp Glu Val Val Ser Ile Asn Gly Asn Pro Cys Ala
          35                  40                  45

 gat ctc acc tac cct gaa gtc atc aag ctc atg gaa agc ata aca gac      192
 Asp Leu Thr Tyr Pro Glu Val Ile Lys Leu Met Glu Ser Ile Thr Asp
      50                  55                  60

 tct ctc caa atg ctc atc aaa aga cca tcc agt gga ata agt gag gct      240
 Ser Leu Gln Met Leu Ile Lys Arg Pro Ser Ser Gly Ile Ser Glu Ala
  65                  70                  75                  80

 ttg ata tct gaa aat gaa aac aaa aac ctc gag cat ctc aca cat ggg      288
 Leu Ile Ser Glu Asn Glu Asn Lys Asn Leu Glu His Leu Thr His Gly
                  85                  90                  95

 ggt tat gtg gaa agt acc acc ctg cag att cga ccg gcc aca aag acc      336
 Gly Tyr Val Glu Ser Thr Thr Leu Gln Ile Arg Pro Ala Thr Lys Thr
             100                 105                 110

 cag tgc aca gaa ttc ttc ctc gcc cct gtc aag act gaa gtt ccc cta      384
 Gln Cys Thr Glu Phe Phe Leu Ala Pro Val Lys Thr Glu Val Pro Leu
         115                 120                 125

 gct gag aac caa aga agt ggt ccc gac tgt gca ggc agc ttg aaa gaa      432
 Ala Glu Asn Gln Arg Ser Gly Pro Asp Cys Ala Gly Ser Leu Lys Glu
     130                 135                 140

 gaa aca ggc ccg agc tac caa agg gct ccc caa atg cct gac tcc caa      480
 Glu Thr Gly Pro Ser Tyr Gln Arg Ala Pro Gln Met Pro Asp Ser Gln
 145                 150                 155                 160

 aga gga cgc gtg gca gaa gag ctg atc tta agg gag aag gta gaa gcg      528
 Arg Gly Arg Val Ala Glu Glu Leu Ile Leu Arg Glu Lys Val Glu Ala
                 165                 170                 175

 gta cag cct ggg cct gtg gtt gag ctg caa ctg tcc ctt tca cag gag      576
 Val Gln Pro Gly Pro Val Val Glu Leu Gln Leu Ser Leu Ser Gln Glu
             180                 185                 190

 aga cat aag ggc gct agt ggc cct tta gtg gct ctc ccg gga gct gaa      624
 Arg His Lys Gly Ala Ser Gly Pro Leu Val Ala Leu Pro Gly Ala Glu
         195                 200                 205

 aaa tct aag tct cct gac cca gac cct aac ttg tca cat gac agg att      672
 Lys Ser Lys Ser Pro Asp Pro Asp Pro Asn Leu Ser His Asp Arg Ile
     210                 215                 220

 gtc cac ata aat tcg atc cct act aat gag aaa gca gac cct ttc ctg      720
 Val His Ile Asn Ser Ile Pro Thr Asn Glu Lys Ala Asp Pro Phe Leu
 225                 230                 235                 240

 agg tcc agc aag ata atc cag atc tcc agt ggc aga gag ttg aga gtg      768
 Arg Ser Ser Lys Ile Ile Gln Ile Ser Ser Gly Arg Glu Leu Arg Val
                 245                 250                 255

 atc cag gaa agt gaa gca gga gat gcg gga ctg ccc cgg gtg gaa gtg      816
 Ile Gln Glu Ser Glu Ala Gly Asp Ala Gly Leu Pro Arg Val Glu Val
             260                 265                 270

 atc ctc gac tgc tct gac agg cag aag aca gaa ggg tgc agg ctt cag      864
 Ile Leu Asp Cys Ser Asp Arg Gln Lys Thr Glu Gly Cys Arg Leu Gln
         275                 280                 285

 gca gga aag gag tgt gtg gat tct cca gtg gaa gga ggg cag tca gaa      912
 Ala Gly Lys Glu Cys Val Asp Ser Pro Val Glu Gly Gly Gln Ser Glu
     290                 295                 300

 gca cct cct tct ctg gta tcc ttt gcc gtc tca tca gaa ggc aca gag      960
 Ala Pro Pro Ser Leu Val Ser Phe Ala Val Ser Ser Glu Gly Thr Glu
 305                 310                 315                 320

 cag gga gaa gat cca cgc tcg gaa aaa gat cac agc aga cct cac aag     1008
 Gln Gly Glu Asp Pro Arg Ser Glu Lys Asp His Ser Arg Pro His Lys
                 325                 330                 335

 cac cga gcg cgg cat gca cgt aag ttc tgc ctg ggc ttt cag aag ggg     1056
 His Arg Ala Arg His Ala Arg Lys Phe Cys Leu Gly Phe Gln Lys Gly
             340                 345                 350

 ctt ggg agt tgg ggg cat ttt gct gct tct ttg ctt gca tga             1098
 Leu Gly Ser Trp Gly His Phe Ala Ala Ser Leu Leu Ala 
         355                 360                 365





      <210> 248
      <211> 405
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(405)

      <400> 248
  atg gct gtg ctc cct gag gac cca gct gca gaa ttc cac ctg atc ctc      48
  Met Ala Val Leu Pro Glu Asp Pro Ala Ala Glu Phe His Leu Ile Leu
    1               5                  10                  15

 atc tca ctc tct cct ttg ctg agt ctg ggg ctt gtc ttt gct acc att       96
 Ile Ser Leu Ser Pro Leu Leu Ser Leu Gly Leu Val Phe Ala Thr Ile
              20                  25                  30

 cct gtt agt gct aag tgg ggc ctt gag gtc ata aat agt aac tgg tgc      144
 Pro Val Ser Ala Lys Trp Gly Leu Glu Val Ile Asn Ser Asn Trp Cys
          35                  40                  45

 atg ggc tgt gct ccg gag ttg ggc tgc tca caa acc aag ctg tct gtt      192
 Met Gly Cys Ala Pro Glu Leu Gly Cys Ser Gln Thr Lys Leu Ser Val
      50                  55                  60

 tat atg gag tgc ctg gag ggc atc tgc cat gag tct gtc gct aac tgc      240
 Tyr Met Glu Cys Leu Glu Gly Ile Cys His Glu Ser Val Ala Asn Cys
  65                  70                  75                  80

 act aac cag gag agc tgg ctg gtt ggg gag aag aca cta acc ctg aca      288
 Thr Asn Gln Glu Ser Trp Leu Val Gly Glu Lys Thr Leu Thr Leu Thr
                  85                  90                  95

 ctg ctc agc cag ctt ctg gta cag atc atg cct tac acc tat tct gtc      336
 Leu Leu Ser Gln Leu Leu Val Gln Ile Met Pro Tyr Thr Tyr Ser Val
             100                 105                 110

 tac act ctg ctc agc tgt tca gag ggt tca cag tgc agc tct gct gtg      384
 Tyr Thr Leu Leu Ser Cys Ser Glu Gly Ser Gln Cys Ser Ser Ala Val
         115                 120                 125

 cgt gcc gag tcc cat ttc taa                                          405
 Arg Ala Glu Ser His Phe 
     130





      <210> 249
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 249
  atg gag tat gtg ctg aac tcc tca acc tgg cgc aca ttc ctt gaa gcc      48
  Met Glu Tyr Val Leu Asn Ser Ser Thr Trp Arg Thr Phe Leu Glu Ala
    1               5                  10                  15

 ctg tac aca tcc tgg ctg tat ctt ttg caa gtg cct cct gca tgt gcc       96
 Leu Tyr Thr Ser Trp Leu Tyr Leu Leu Gln Val Pro Pro Ala Cys Ala
              20                  25                  30

 tta tgc tcc agc tgt gcc aac aac ctt cga gaa acc tgc gca gaa gct      144
 Leu Cys Ser Ser Cys Ala Asn Asn Leu Arg Glu Thr Cys Ala Glu Ala
          35                  40                  45

 cac ctt cac acc tgt gct tgg tag                                      168
 His Leu His Thr Cys Ala Trp 
      50                  55





      <210> 250
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 250
  atg ccc agc ctg tat gct ttt atc atc atg gtc tta aca acc atc aca      48
  Met Pro Ser Leu Tyr Ala Phe Ile Ile Met Val Leu Thr Thr Ile Thr
    1               5                  10                  15

 tta ctg tgc acg tca gtc atc acc ttg cca gta tcc tca acc cca gtc       96
 Leu Leu Cys Thr Ser Val Ile Thr Leu Pro Val Ser Ser Thr Pro Val
              20                  25                  30

 aca cgt gcc agc caa agc ccc aac cct aca gcc aaa gca ctg act gca      144
 Thr Arg Ala Ser Gln Ser Pro Asn Pro Thr Ala Lys Ala Leu Thr Ala
          35                  40                  45

 ggc ctg tgt ggc tcc tcc tcc cag gtc cat gga cag aaa gct gct tgg      192
 Gly Leu Cys Gly Ser Ser Ser Gln Val His Gly Gln Lys Ala Ala Trp
      50                  55                  60

 gag gac cca gtg gaa tgg gtc cgg gac aca ctt ccc tgg cca tca gcc      240
 Glu Asp Pro Val Glu Trp Val Arg Asp Thr Leu Pro Trp Pro Ser Ala
  65                  70                  75                  80

 caa caa gac caa tca aag ctg tac cac ctg ccc cca ccc acc gtg ggc      288
 Gln Gln Asp Gln Ser Lys Leu Tyr His Leu Pro Pro Pro Thr Val Gly
                  85                  90                  95

 cct cac agc att gcc tca cct ccc gag gat agg aca gtc aaa gac agc      336
 Pro His Ser Ile Ala Ser Pro Pro Glu Asp Arg Thr Val Lys Asp Ser
             100                 105                 110

 acc cca agt tct ctg gac tca gat cct ctg atg gcc atg ctg ctg aaa      384
 Thr Pro Ser Ser Leu Asp Ser Asp Pro Leu Met Ala Met Leu Leu Lys
         115                 120                 125

 ctt caa gaa gct gcc aac tac att gag tct cca gat cga gaa acc atc      432
 Leu Gln Glu Ala Ala Asn Tyr Ile Glu Ser Pro Asp Arg Glu Thr Ile
     130                 135                 140

 ctg gac ccc aac ctt cag gca aca ctt taa                              462
 Leu Asp Pro Asn Leu Gln Ala Thr Leu 
 145                 150





      <210> 251
      <211> 279
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(279)

      <400> 251
  atg acc tca gtt tca aca cag ttg tcc tta gtc ctc atg tca ctg ctt      48
  Met Thr Ser Val Ser Thr Gln Leu Ser Leu Val Leu Met Ser Leu Leu
    1               5                  10                  15

 ttg gtg ctg cct gtt gtg gaa gca gta gaa gcc ggt gat gca gtc gcc       96
 Leu Val Leu Pro Val Val Glu Ala Val Glu Ala Gly Asp Ala Val Ala
              20                  25                  30

 ctc ttg tta ggt gtg gtt ctc agc att aca ggc att tgt gct gct cgg      144
 Leu Leu Leu Gly Val Val Leu Ser Ile Thr Gly Ile Cys Ala Ala Arg
          35                  40                  45

 gag tat atg cac gaa aaa gaa atg gac aga ttc tat caa cgt gtt gct      192
 Glu Tyr Met His Glu Lys Glu Met Asp Arg Phe Tyr Gln Arg Val Ala
      50                  55                  60

 ttt aat gta ata gac caa tta gct gtt acg tgc aat gtt cca ttt cac      240
 Phe Asn Val Ile Asp Gln Leu Ala Val Thr Cys Asn Val Pro Phe His
  65                  70                  75                  80

 tgg gaa caa tgt atg ttc caa aag gag aga gga atc tga                  279
 Trp Glu Gln Cys Met Phe Gln Lys Glu Arg Gly Ile 
                  85                  90





      <210> 252
      <211> 222
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(222)

      <400> 252
  atg ccc tgg gcc cct tca gtc tgc ctg cgg ctc tgt ggc atc cct gcc      48
  Met Pro Trp Ala Pro Ser Val Cys Leu Arg Leu Cys Gly Ile Pro Ala
    1               5                  10                  15

 ctg aca ctg ggc acc tgt gcc cct agc aag ccc acc tgg cac acg agg       96
 Leu Thr Leu Gly Thr Cys Ala Pro Ser Lys Pro Thr Trp His Thr Arg
              20                  25                  30

 agg gag ggg ctt tct cac ctg cac acg gtt agg cca ttt tca gtg ctc      144
 Arg Glu Gly Leu Ser His Leu His Thr Val Arg Pro Phe Ser Val Leu
          35                  40                  45

 gtg ggc agt cac gga cag cag cag aaa ctc ctc agc ccc ttt gtt act      192
 Val Gly Ser His Gly Gln Gln Gln Lys Leu Leu Ser Pro Phe Val Thr
      50                  55                  60

 tca gaa cgc ctg ccc aca tgc atc ttc tga                              222
 Ser Glu Arg Leu Pro Thr Cys Ile Phe 
  65                  70





      <210> 253
      <211> 246
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(246)

      <400> 253
  atg act atc cac atc ctc atc ctg ctg ttg ctc ctc gcc ttc tcc gcc      48
  Met Thr Ile His Ile Leu Ile Leu Leu Leu Leu Leu Ala Phe Ser Ala
    1               5                  10                  15

 caa ggg gac ctg gac act gca gcc agg cga ggc cag cac cag gtc ccc       96
 Gln Gly Asp Leu Asp Thr Ala Ala Arg Arg Gly Gln His Gln Val Pro
              20                  25                  30

 cag cac cgc ggg cac gtc tgc tac ctg ggc gag ccc tcg ggg aag gcc      144
 Gln His Arg Gly His Val Cys Tyr Leu Gly Glu Pro Ser Gly Lys Ala
          35                  40                  45

 agc cac gag ccc cag gac ccc tac agc tat ggg cgc cgc cgg tgg cgc      192
 Ser His Glu Pro Gln Asp Pro Tyr Ser Tyr Gly Arg Arg Arg Trp Arg
      50                  55                  60

 gag gcg gaa gcc cgg ctc ggt tcc cag gat tcc ggc ctg cag cga ggg      240
 Glu Ala Glu Ala Arg Leu Gly Ser Gln Asp Ser Gly Leu Gln Arg Gly
  65                  70                  75                  80

 ggc tag                                                              246
 Gly 






      <210> 254
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 254
  atg agg gct gcc cgg agg ttg cca ttt ttc atg gcc aga gct tgg tat      48
  Met Arg Ala Ala Arg Arg Leu Pro Phe Phe Met Ala Arg Ala Trp Tyr
    1               5                  10                  15

 cac tta ccc aga ggg gca gag ccg gcc ata tca gac tgt gca tct cac       96
 His Leu Pro Arg Gly Ala Glu Pro Ala Ile Ser Asp Cys Ala Ser His
              20                  25                  30

 gtg tgt ggt ttc ttg ggc ccc aca gct gga gac aat ggc agg agc ggc      144
 Val Cys Gly Phe Leu Gly Pro Thr Ala Gly Asp Asn Gly Arg Ser Gly
          35                  40                  45

 ctt gga gag ccc cga ttg tca cct ggc gtc ttg gca ggc agc tga          189
 Leu Gly Glu Pro Arg Leu Ser Pro Gly Val Leu Ala Gly Ser 
      50                  55                  60





      <210> 255
      <211> 777
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(777)

      <400> 255
  atg gcg ggc gca gtt tcg ctc ttg ggt gtg gtg ggg ctg ctg ctt gtg      48
  Met Ala Gly Ala Val Ser Leu Leu Gly Val Val Gly Leu Leu Leu Val
    1               5                  10                  15

 tct gcg ctg tcc ggg gtc cta gga gac cgc gcc aat ccc gac ctc cgg       96
 Ser Ala Leu Ser Gly Val Leu Gly Asp Arg Ala Asn Pro Asp Leu Arg
              20                  25                  30

 gca cac cca ggg aac gca gcc cac ccc ggc tct gga gcc acg gaa ccc      144
 Ala His Pro Gly Asn Ala Ala His Pro Gly Ser Gly Ala Thr Glu Pro
          35                  40                  45

 cgg cgg cga cca ccg ctc aag gat caa cgc gag cgg acc cgg gcc ggg      192
 Arg Arg Arg Pro Pro Leu Lys Asp Gln Arg Glu Arg Thr Arg Ala Gly
      50                  55                  60

 tcg ctg cct ctg ggg gcg ctg tac acc gcg gcc gtc gcg gct ttt gtg      240
 Ser Leu Pro Leu Gly Ala Leu Tyr Thr Ala Ala Val Ala Ala Phe Val
  65                  70                  75                  80

 ctg tac aag tgt ttg cag ggg aaa gat gaa act gcg gtt ctc cac gag      288
 Leu Tyr Lys Cys Leu Gln Gly Lys Asp Glu Thr Ala Val Leu His Glu
                  85                  90                  95

 gag gca agc aag cag cag cca ctg cag tca gag caa cag ctg gcc cag      336
 Glu Ala Ser Lys Gln Gln Pro Leu Gln Ser Glu Gln Gln Leu Ala Gln
             100                 105                 110

 ttg aca caa cag ctg gcc cag aca gag cag cac ctg aac aac ctg atg      384
 Leu Thr Gln Gln Leu Ala Gln Thr Glu Gln His Leu Asn Asn Leu Met
         115                 120                 125

 gcc cag ctg gac ccc ctt ttt gag cgt gtg act act ctg gct gga gcc      432
 Ala Gln Leu Asp Pro Leu Phe Glu Arg Val Thr Thr Leu Ala Gly Ala
     130                 135                 140

 cag cag gag ctt ctg aac atg aag cta tgg acc atc cac gag ctg ctg      480
 Gln Gln Glu Leu Leu Asn Met Lys Leu Trp Thr Ile His Glu Leu Leu
 145                 150                 155                 160

 caa gat agc aag ccg gac aag gat atg gag gct tca gaa cca ggt gaa      528
 Gln Asp Ser Lys Pro Asp Lys Asp Met Glu Ala Ser Glu Pro Gly Glu
                 165                 170                 175

 ggc tcg gga ggc gag tct gct gga ggt gga gac aaa gtc tct gaa act      576
 Gly Ser Gly Gly Glu Ser Ala Gly Gly Gly Asp Lys Val Ser Glu Thr
             180                 185                 190

 gga aca ttc ctg atc tct ccc cac aca gag gcc agc aga cct ctt cct      624
 Gly Thr Phe Leu Ile Ser Pro His Thr Glu Ala Ser Arg Pro Leu Pro
         195                 200                 205

 gag gac ttc tgt tta aag gag gac gag gag gag att ggt gac agt cag      672
 Glu Asp Phe Cys Leu Lys Glu Asp Glu Glu Glu Ile Gly Asp Ser Gln
     210                 215                 220

 gcc tgg gag gag ccc aca aac tgg agc aca gag aca tgg aac cta gct      720
 Ala Trp Glu Glu Pro Thr Asn Trp Ser Thr Glu Thr Trp Asn Leu Ala
 225                 230                 235                 240

 act tcc tgg gag gtg cct aag gac aac tgg gcc ttc ttg aag agc tgt      768
 Thr Ser Trp Glu Val Pro Lys Asp Asn Trp Ala Phe Leu Lys Ser Cys
                 245                 250                 255

 cct tat tag                                                          777
 Pro Tyr 






      <210> 256
      <211> 162
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(162)

      <400> 256
  atg gcc ttt ttc ttt ata aga aca ttg gta ttt gca gag gaa ttg ttc      48
  Met Ala Phe Phe Phe Ile Arg Thr Leu Val Phe Ala Glu Glu Leu Phe
    1               5                  10                  15

 caa aaa ccc tac aga gcc atg gta gga ctt cag ttg ttt act aat gct       96
 Gln Lys Pro Tyr Arg Ala Met Val Gly Leu Gln Leu Phe Thr Asn Ala
              20                  25                  30

 ttt cat tct ttc atg cca aag aat atg tat ggt act agg att aag aaa      144
 Phe His Ser Phe Met Pro Lys Asn Met Tyr Gly Thr Arg Ile Lys Lys
          35                  40                  45

 aaa aga ctg ccg gag taa                                              162
 Lys Arg Leu Pro Glu 
      50





      <210> 257
      <211> 1380
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1380)

      <400> 257
  atg gct act gac caa ctc atg gtt aaa tgg aag ctg ggc ctc caa gcc      48
  Met Ala Thr Asp Gln Leu Met Val Lys Trp Lys Leu Gly Leu Gln Ala
    1               5                  10                  15

 ctt ctc gga ctc aga atc ctc cca gca gat acc cag gca gag gag tgt       96
 Leu Leu Gly Leu Arg Ile Leu Pro Ala Asp Thr Gln Ala Glu Glu Cys
              20                  25                  30

 gaa ctc tca gcc cct aaa aag cag ctt aga acc ttt cac agc aag tca      144
 Glu Leu Ser Ala Pro Lys Lys Gln Leu Arg Thr Phe His Ser Lys Ser
          35                  40                  45

 aag cag caa aag tca gca cag agg gta gaa agg aaa cct ccg aga ctg      192
 Lys Gln Gln Lys Ser Ala Gln Arg Val Glu Arg Lys Pro Pro Arg Leu
      50                  55                  60

 gag gga gaa gcg gac acg agg act gtg aag gat gac act gcc gag gag      240
 Glu Gly Glu Ala Asp Thr Arg Thr Val Lys Asp Asp Thr Ala Glu Glu
  65                  70                  75                  80

 tgg gca gct gga ggg atg ctc tgg ctg gag cag agt gaa agc ctt ttt      288
 Trp Ala Ala Gly Gly Met Leu Trp Leu Glu Gln Ser Glu Ser Leu Phe
                  85                  90                  95

 gaa gag gtg gaa ttt aag ccg ggc ttt gta tat cgg aag gtt ctt aga      336
 Glu Glu Val Glu Phe Lys Pro Gly Phe Val Tyr Arg Lys Val Leu Arg
             100                 105                 110

 gcc aaa ggg gtt gtg aag aag tgt gtg agc cgc acc caa gca ctg gtg      384
 Ala Lys Gly Val Val Lys Lys Cys Val Ser Arg Thr Gln Ala Leu Val
         115                 120                 125

 ggc ttc agt tac gga gac acc aag gtc gtg tcc acc tcc ttc atc acg      432
 Gly Phe Ser Tyr Gly Asp Thr Lys Val Val Ser Thr Ser Phe Ile Thr
     130                 135                 140

 cct gtg ggg ggc gcc atg ccc tgc ccg ctg ctc cag gtt gga gat tat      480
 Pro Val Gly Gly Ala Met Pro Cys Pro Leu Leu Gln Val Gly Asp Tyr
 145                 150                 155                 160

 gtg ttt gcc aaa att gtg ata ccc aaa gga ttt gac ttc tat gtc cct      528
 Val Phe Ala Lys Ile Val Ile Pro Lys Gly Phe Asp Phe Tyr Val Pro
                 165                 170                 175

 gcc att gtc ata gca ctt ccc aat aag cat gtg gcc aca gaa aaa ttc      576
 Ala Ile Val Ile Ala Leu Pro Asn Lys His Val Ala Thr Glu Lys Phe
             180                 185                 190

 tac aca gtt ttg aag tgt aac aac cgg aga gga gta tgc ccc cag gac      624
 Tyr Thr Val Leu Lys Cys Asn Asn Arg Arg Gly Val Cys Pro Gln Asp
         195                 200                 205

 ccc agt gtg gcc cca gcc ggc tcc atg agc ttg acc tcc agc cag gtg      672
 Pro Ser Val Ala Pro Ala Gly Ser Met Ser Leu Thr Ser Ser Gln Val
     210                 215                 220

 gaa gac tca ctg ctt cct gaa tgc ggt ctc tgt gcc ttc acc aga tta      720
 Glu Asp Ser Leu Leu Pro Glu Cys Gly Leu Cys Ala Phe Thr Arg Leu
 225                 230                 235                 240

 agt att ctc cct gga cag cta ttc ctt gcc ctc agc cac ctg ggg aac      768
 Ser Ile Leu Pro Gly Gln Leu Phe Leu Ala Leu Ser His Leu Gly Asn
                 245                 250                 255

 tcc aag act gag ctc aaa cgt caa cac cac cat gtg atg tcc cag cac      816
 Ser Lys Thr Glu Leu Lys Arg Gln His His His Val Met Ser Gln His
             260                 265                 270

 cct agc ccc ccc agg acg ggt ccg tat act caa gtt ctc cgt gcc gtg      864
 Pro Ser Pro Pro Arg Thr Gly Pro Tyr Thr Gln Val Leu Arg Ala Val
         275                 280                 285

 gga ggc tcc caa aca cca aag gct cgt gga aat gaa ctg agt gga cct      912
 Gly Gly Ser Gln Thr Pro Lys Ala Arg Gly Asn Glu Leu Ser Gly Pro
     290                 295                 300

 aag ccc agc cta aag cat tgg gtt cac agc gct cca gag act cct ttc      960
 Lys Pro Ser Leu Lys His Trp Val His Ser Ala Pro Glu Thr Pro Phe
 305                 310                 315                 320

 cat ggg aag agg gac gtg ggc aag gag ctg aga agc agc cgt ggg gat     1008
 His Gly Lys Arg Asp Val Gly Lys Glu Leu Arg Ser Ser Arg Gly Asp
                 325                 330                 335

 ggc ttg gac atc tct gta gac ccc gca gcc atc aag gca gga gag gat     1056
 Gly Leu Asp Ile Ser Val Asp Pro Ala Ala Ile Lys Ala Gly Glu Asp
             340                 345                 350

 gtg gag gcg agg aac tct gct ttc ctc ttc tgg cca ctg aaa gaa gcg     1104
 Val Glu Ala Arg Asn Ser Ala Phe Leu Phe Trp Pro Leu Lys Glu Ala
         355                 360                 365

 gac acg cag gat tcc aga gag cca aga cga gag aag ccc agg agg aaa     1152
 Asp Thr Gln Asp Ser Arg Glu Pro Arg Arg Glu Lys Pro Arg Arg Lys
     370                 375                 380

 aag agg ccc gcc aag cag cca ctc cag cag gcg gcg ccc tcg gac tcg     1200
 Lys Arg Pro Ala Lys Gln Pro Leu Gln Gln Ala Ala Pro Ser Asp Ser
 385                 390                 395                 400

 gac ggc tcc tcc cac ggc atc agc tcc cat ggg tcc tgc cag ggg aca     1248
 Asp Gly Ser Ser His Gly Ile Ser Ser His Gly Ser Cys Gln Gly Thr
                 405                 410                 415

 cac ccc gag ccc agg tgc aca agg cca tca ttt gat gtg ttc aat gat     1296
 His Pro Glu Pro Arg Cys Thr Arg Pro Ser Phe Asp Val Phe Asn Asp
             420                 425                 430

 agt gcc tac ttc agt gta atg gag gaa gtt gca att aca acg gtg aac     1344
 Ser Ala Tyr Phe Ser Val Met Glu Glu Val Ala Ile Thr Thr Val Asn
         435                 440                 445

 ttc cac ctc caa cca ata cag aat ggc agc aac tag                     1380
 Phe His Leu Gln Pro Ile Gln Asn Gly Ser Asn 
     450                 455





      <210> 258
      <211> 858
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(858)

      <400> 258
  atg gca agg aga gga gtg gcc agt ttt ctg acc agc ttt ctg tcg ggg      48
  Met Ala Arg Arg Gly Val Ala Ser Phe Leu Thr Ser Phe Leu Ser Gly
    1               5                  10                  15

 gtg cct gca gaa gca ctt cag ccc cca gtc acc gtg cag agc cca cca       96
 Val Pro Ala Glu Ala Leu Gln Pro Pro Val Thr Val Gln Ser Pro Pro
              20                  25                  30

 gct ggg gga tcc ccc aga gac cgc tgc ctc agc ggg agc cac ctg gaa      144
 Ala Gly Gly Ser Pro Arg Asp Arg Cys Leu Ser Gly Ser His Leu Glu
          35                  40                  45

 gaa cca gaa ctc cag cct gga gct gct cgt ggg ggc cag cca tcc ccc      192
 Glu Pro Glu Leu Gln Pro Gly Ala Ala Arg Gly Gly Gln Pro Ser Pro
      50                  55                  60

 ctg tcc aca cac tcg tcc cag ctc cat ctc cgg gcc ccg gcg ctg acc      240
 Leu Ser Thr His Ser Ser Gln Leu His Leu Arg Ala Pro Ala Leu Thr
  65                  70                  75                  80

 gtg gag gat ctc agg gcc cag gcc tcc ttg tcc aag gac tcc cct tgg      288
 Val Glu Asp Leu Arg Ala Gln Ala Ser Leu Ser Lys Asp Ser Pro Trp
                  85                  90                  95

 ggt ccc tgg ctc cct gag ctc ttg ggc tgc ctg ggg cct ccg ctg aca      336
 Gly Pro Trp Leu Pro Glu Leu Leu Gly Cys Leu Gly Pro Pro Leu Thr
             100                 105                 110

 ctc cag tgc cga gaa ggc tgc act ccc aag cct gct gtt ccc acg gtg      384
 Leu Gln Cys Arg Glu Gly Cys Thr Pro Lys Pro Ala Val Pro Thr Val
         115                 120                 125

 tca ctg gct gag gga tgg ggt gaa att gcc gag gaa gcc cct gga ggc      432
 Ser Leu Ala Glu Gly Trp Gly Glu Ile Ala Glu Glu Ala Pro Gly Gly
     130                 135                 140

 aaa aga gcc aag gac aga acc tac ggg gag aca tca agg gga gga agt      480
 Lys Arg Ala Lys Asp Arg Thr Tyr Gly Glu Thr Ser Arg Gly Gly Ser
 145                 150                 155                 160

 gag ccc cag ccc cca gga gag aga gaa aac gtc tca gag gcc atg aag      528
 Glu Pro Gln Pro Pro Gly Glu Arg Glu Asn Val Ser Glu Ala Met Lys
                 165                 170                 175

 agg ccg ttt cca gat gct gcc gag gga gca gaa gag gag cct ccc ccc      576
 Arg Pro Phe Pro Asp Ala Ala Glu Gly Ala Glu Glu Glu Pro Pro Pro
             180                 185                 190

 agc gct ggg cag cga gag ggc gac gtg acc ttt gag aat tct gct tcc      624
 Ser Ala Gly Gln Arg Glu Gly Asp Val Thr Phe Glu Asn Ser Ala Ser
         195                 200                 205

 cca gca caa ccg ggc gag aag ctg gct cca aag ggc ttt ctt caa aga      672
 Pro Ala Gln Pro Gly Glu Lys Leu Ala Pro Lys Gly Phe Leu Gln Arg
     210                 215                 220

 cta gta caa gcc cct gag ggc tcc gct gat tgg aca cgt ttc cca gcc      720
 Leu Val Gln Ala Pro Glu Gly Ser Ala Asp Trp Thr Arg Phe Pro Ala
 225                 230                 235                 240

 tgg tcc aag gcc gct gat gct cca tcc ttc ctc tgg ttg ctc agg tta      768
 Trp Ser Lys Ala Ala Asp Ala Pro Ser Phe Leu Trp Leu Leu Arg Leu
                 245                 250                 255

 agc ccc ttg gct cca caa atg gcc aag aag cac atg aaa aga tgc tca      816
 Ser Pro Leu Ala Pro Gln Met Ala Lys Lys His Met Lys Arg Cys Ser
             260                 265                 270

 cca tca tta gtc att agg gac tgc aaa tct aac ctg caa tga              858
 Pro Ser Leu Val Ile Arg Asp Cys Lys Ser Asn Leu Gln 
         275                 280                 285





      <210> 259
      <211> 546
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(546)

      <400> 259
  atg ctt ttc cgc aac cgc ttc ttg ctg ctg ctg gcc ctg gct gcg ctg      48
  Met Leu Phe Arg Asn Arg Phe Leu Leu Leu Leu Ala Leu Ala Ala Leu
    1               5                  10                  15

 ctg gcc ttt gtg agc ctc agc ctg cag ttc tgg agc tct ttg tcc agt       96
 Leu Ala Phe Val Ser Leu Ser Leu Gln Phe Trp Ser Ser Leu Ser Ser
              20                  25                  30

 gga gaa gaa tca caa gcc gac acc ctg gaa tac cag gtg ctg tgt gct      144
 Gly Glu Glu Ser Gln Ala Asp Thr Leu Glu Tyr Gln Val Leu Cys Ala
          35                  40                  45

 ggg aca ggc ccc ttc cca gcc ttc ctc ctg gag ccc ggc ctg cac atc      192
 Gly Thr Gly Pro Phe Pro Ala Phe Leu Leu Glu Pro Gly Leu His Ile
      50                  55                  60

 gac cct gtc cac ctg atc ccg gtg tcg act cct aag aat gga atg agt      240
 Asp Pro Val His Leu Ile Pro Val Ser Thr Pro Lys Asn Gly Met Ser
  65                  70                  75                  80

 agc aag agt cga aag aga atc atg ccc gac cct gtg acg gag ccc cct      288
 Ser Lys Ser Arg Lys Arg Ile Met Pro Asp Pro Val Thr Glu Pro Pro
                  85                  90                  95

 gtg aca gac ccc gtt tat gaa gct ctt ttg tac tgc aac atc ccc agc      336
 Val Thr Asp Pro Val Tyr Glu Ala Leu Leu Tyr Cys Asn Ile Pro Ser
             100                 105                 110

 gtg gcc gag cgc agc atg gaa ggt cat gcc ccg cat cat ttt aag ctg      384
 Val Ala Glu Arg Ser Met Glu Gly His Ala Pro His His Phe Lys Leu
         115                 120                 125

 gtc tca gtg cat gtg ttc att cgc cac gga gac agg tac cca ctg tat      432
 Val Ser Val His Val Phe Ile Arg His Gly Asp Arg Tyr Pro Leu Tyr
     130                 135                 140

 gtc att ccc aaa aca aag cga cca gaa att gac tgc act ctg gtg gct      480
 Val Ile Pro Lys Thr Lys Arg Pro Glu Ile Asp Cys Thr Leu Val Ala
 145                 150                 155                 160

 aac agg gcc cct gtc aca gtg atg cca gga ccc tct aat ggg gcc att      528
 Asn Arg Ala Pro Val Thr Val Met Pro Gly Pro Ser Asn Gly Ala Ile
                 165                 170                 175

 ttt ggc gct ccc att tga                                              546
 Phe Gly Ala Pro Ile 
             180





      <210> 260
      <211> 1452
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1452)

      <400> 260
  atg cac gtg ctg ctg gcg ctg agc ggc cgc ggc tgc ctg gtg ctc cgc      48
  Met His Val Leu Leu Ala Leu Ser Gly Arg Gly Cys Leu Val Leu Arg
    1               5                  10                  15

 cac gtg gtg atg ggc agc cac tcg ccc tgt gcc cac acc ccc tgt gcc       96
 His Val Val Met Gly Ser His Ser Pro Cys Ala His Thr Pro Cys Ala
              20                  25                  30

 ccg cca gcc ccc aca ggt gcc aag agg acc ctt gcg gcc agc ggc agc      144
 Pro Pro Ala Pro Thr Gly Ala Lys Arg Thr Leu Ala Ala Ser Gly Ser
          35                  40                  45

 cag tcc tcc aac ggc cct gag cca ggt ggc cag cag ctg aaa aca cgc      192
 Gln Ser Ser Asn Gly Pro Glu Pro Gly Gly Gln Gln Leu Lys Thr Arg
      50                  55                  60

 aca ttg tcg ggg atg gcg tcc aag act acc acc acc atc atc cct aag      240
 Thr Leu Ser Gly Met Ala Ser Lys Thr Thr Thr Thr Ile Ile Pro Lys
  65                  70                  75                  80

 cga atc gcc cac agt cca tcc tta cag agt tta aag aaa ccc att atc      288
 Arg Ile Ala His Ser Pro Ser Leu Gln Ser Leu Lys Lys Pro Ile Ile
                  85                  90                  95

 ccc aaa gag ttt ggg ggc aaa gtc ccc acc gtc atc cgc cag cgc tat      336
 Pro Lys Glu Phe Gly Gly Lys Val Pro Thr Val Ile Arg Gln Arg Tyr
             100                 105                 110

 ctc aac ctg ttc atc gag gag tgt ctc aag ttc tgt acc tcc aac cag      384
 Leu Asn Leu Phe Ile Glu Glu Cys Leu Lys Phe Cys Thr Ser Asn Gln
         115                 120                 125

 gag gcc ata gag aag gca ctg aac gag gag aag gtg gcc tat gac cgc      432
 Glu Ala Ile Glu Lys Ala Leu Asn Glu Glu Lys Val Ala Tyr Asp Arg
     130                 135                 140

 agc ccc agc aag aac atc tac ctg aat gtg gcc gtg aac acc ctc aag      480
 Ser Pro Ser Lys Asn Ile Tyr Leu Asn Val Ala Val Asn Thr Leu Lys
 145                 150                 155                 160

 aag ctc agg ggc ctg gcc ccc agc gct gtg ccc ggc ctc agc aaa acc      528
 Lys Leu Arg Gly Leu Ala Pro Ser Ala Val Pro Gly Leu Ser Lys Thr
                 165                 170                 175

 agt ggc cgc agg gtt gtg tcc cac gag gtg gtg ttg ggg ggc agg ttg      576
 Ser Gly Arg Arg Val Val Ser His Glu Val Val Leu Gly Gly Arg Leu
             180                 185                 190

 gcc gcc aag acc agc ttc tcg ctc agc cgt cca agc agc ccc cgg gtg      624
 Ala Ala Lys Thr Ser Phe Ser Leu Ser Arg Pro Ser Ser Pro Arg Val
         195                 200                 205

 gag gac ctg aaa ggg gct gcc ctg tac agc cgc ctc agg gag tac ctg      672
 Glu Asp Leu Lys Gly Ala Ala Leu Tyr Ser Arg Leu Arg Glu Tyr Leu
     210                 215                 220

 ctc acc cag gac cag ctc aag gag aac ggc tac ccc ttc ccg cac cca      720
 Leu Thr Gln Asp Gln Leu Lys Glu Asn Gly Tyr Pro Phe Pro His Pro
 225                 230                 235                 240

 gag cgg ccc ggg ggc gca atc atc ttc aca gct gag gag aag agg ccc      768
 Glu Arg Pro Gly Gly Ala Ile Ile Phe Thr Ala Glu Glu Lys Arg Pro
                 245                 250                 255

 aag gac tgt gag tcg ctg gcc tgc gac ggc cta gtg gcc gga ggc tgg      816
 Lys Asp Cys Glu Ser Leu Ala Cys Asp Gly Leu Val Ala Gly Gly Trp
             260                 265                 270

 gag acc cag tac atg tgc tgc tcg gct gcc gcc ggc tct gtc ggc tgc      864
 Glu Thr Gln Tyr Met Cys Cys Ser Ala Ala Ala Gly Ser Val Gly Cys
         275                 280                 285

 caa gtc gca aag caa cac gtg cag gat ggc cgg aag gag cgc ctt gag      912
 Gln Val Ala Lys Gln His Val Gln Asp Gly Arg Lys Glu Arg Leu Glu
     290                 295                 300

 ggc ttc gtg aag acc ttt gag aaa gag ctc tca gga gac acc cac ccg      960
 Gly Phe Val Lys Thr Phe Glu Lys Glu Leu Ser Gly Asp Thr His Pro
 305                 310                 315                 320

 ggg atc tac gcc ctg gac tgc gag atg tcc tac acc aca tat ggc ctg     1008
 Gly Ile Tyr Ala Leu Asp Cys Glu Met Ser Tyr Thr Thr Tyr Gly Leu
                 325                 330                 335

 gag ctg acg cgc gtc acg gtg gtc gac acg gac gtg cac gtg gtt tat     1056
 Glu Leu Thr Arg Val Thr Val Val Asp Thr Asp Val His Val Val Tyr
             340                 345                 350

 gac acc ttc gtg aag cct gac aac gag atc gtg gac tac aac acc agg     1104
 Asp Thr Phe Val Lys Pro Asp Asn Glu Ile Val Asp Tyr Asn Thr Arg
         355                 360                 365

 ttt tcg ggg gtg acg gag gct gac ctt gcc gac aca agt gtc acg ctg     1152
 Phe Ser Gly Val Thr Glu Ala Asp Leu Ala Asp Thr Ser Val Thr Leu
     370                 375                 380

 cgt gac gtc cag gcc gtt ctg ctg agc atg ttc agc gct gac acc atc     1200
 Arg Asp Val Gln Ala Val Leu Leu Ser Met Phe Ser Ala Asp Thr Ile
 385                 390                 395                 400

 ctc atc gga cac agc ctg gag agc gac ctc ctg gcc ctg aag gtc atc     1248
 Leu Ile Gly His Ser Leu Glu Ser Asp Leu Leu Ala Leu Lys Val Ile
                 405                 410                 415

 cac agc acc gtg gtg gac acg tct gtg ctc ttc ccc cac cgc ctg ggc     1296
 His Ser Thr Val Val Asp Thr Ser Val Leu Phe Pro His Arg Leu Gly
             420                 425                 430

 ctc ccc tac aag cgg tcc ctg cgg aac ctc atg gcc gac tac ctc aga     1344
 Leu Pro Tyr Lys Arg Ser Leu Arg Asn Leu Met Ala Asp Tyr Leu Arg
         435                 440                 445

 cag atc atc cag gac aat gtg gat ggg cac agc tcc agc gag gac gcc     1392
 Gln Ile Ile Gln Asp Asn Val Asp Gly His Ser Ser Ser Glu Asp Ala
     450                 455                 460

 ggc gcc tgc atg cac ctg gtg atc tgg aag gtt cga gaa gac gcc aag     1440
 Gly Ala Cys Met His Leu Val Ile Trp Lys Val Arg Glu Asp Ala Lys
 465                 470                 475                 480

 acc aag cga tga                                                     1452
 Thr Lys Arg 






      <210> 261
      <211> 1218
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1218)

      <400> 261
  atg aaa gca ggg acc ata tca att att ctt agc acc tgg ctt gtt ctg      48
  Met Lys Ala Gly Thr Ile Ser Ile Ile Leu Ser Thr Trp Leu Val Leu
    1               5                  10                  15

 tgt ctg aca caa att ata gtg aac att att cac aac act tcc gat tac       96
 Cys Leu Thr Gln Ile Ile Val Asn Ile Ile His Asn Thr Ser Asp Tyr
              20                  25                  30

 cat cca aaa gtt ttg cga ttt ttg aat gtg gct ttt gat ggc aca ggc      144
 His Pro Lys Val Leu Arg Phe Leu Asn Val Ala Phe Asp Gly Thr Gly
          35                  40                  45

 gac tgc tta att gct ggg gac cac caa gga aat att tat gtt ttt gac      192
 Asp Cys Leu Ile Ala Gly Asp His Gln Gly Asn Ile Tyr Val Phe Asp
      50                  55                  60

 tta cat gga aac agc ctc aag tat att gtc ctg gtc atc ctg atg gat      240
 Leu His Gly Asn Ser Leu Lys Tyr Ile Val Leu Val Ile Leu Met Asp
  65                  70                  75                  80

 gtg ttc acg gat gtg gag atc ttc tgt gac att cta gag gca gcc aac      288
 Val Phe Thr Asp Val Glu Ile Phe Cys Asp Ile Leu Glu Ala Ala Asn
                  85                  90                  95

 aag cgt ggg gtg ttc gtt tgt gtg ctc ctg gac cag gga ggt gtg aag      336
 Lys Arg Gly Val Phe Val Cys Val Leu Leu Asp Gln Gly Gly Val Lys
             100                 105                 110

 ctc ttc cag gag atg tgt gac aaa gtc cag atc tct gac agt cac ctc      384
 Leu Phe Gln Glu Met Cys Asp Lys Val Gln Ile Ser Asp Ser His Leu
         115                 120                 125

 aag aac att tcc atc cgg agt gtg gaa gga gag ata tac tgt gcc aag      432
 Lys Asn Ile Ser Ile Arg Ser Val Glu Gly Glu Ile Tyr Cys Ala Lys
     130                 135                 140

 tca ggc agg aaa ttc gct ggc caa atc cgg gag aag ttc atc atc tcg      480
 Ser Gly Arg Lys Phe Ala Gly Gln Ile Arg Glu Lys Phe Ile Ile Ser
 145                 150                 155                 160

 gac tgg aga ttt gtc ctg tct gga tct tac agg att cat gga gaa caa      528
 Asp Trp Arg Phe Val Leu Ser Gly Ser Tyr Arg Ile His Gly Glu Gln
                 165                 170                 175

 ggg ctg agt gag gtg cag acc agc tcc cgc tgc tca gac aca aac acc      576
 Gly Leu Ser Glu Val Gln Thr Ser Ser Arg Cys Ser Asp Thr Asn Thr
             180                 185                 190

 ccc agc agc tcc cag aag gtc tcc ctc tgc ccg gag ctg gag ctg cat      624
 Pro Ser Ser Ser Gln Lys Val Ser Leu Cys Pro Glu Leu Glu Leu His
         195                 200                 205

 cac ata gat ggg gtg aga ggc aag aaa tgt gga ccc ttt ctg gca aga      672
 His Ile Asp Gly Val Arg Gly Lys Lys Cys Gly Pro Phe Leu Ala Arg
     210                 215                 220

 att cca gct ggc agc ttc acc tgg ctc tgc gga cac gtg cac cgg aac      720
 Ile Pro Ala Gly Ser Phe Thr Trp Leu Cys Gly His Val His Arg Asn
 225                 230                 235                 240

 atc ctc tcc aag ttc aca ggc cag gcg gtg gag ctg ttt gac gag gag      768
 Ile Leu Ser Lys Phe Thr Gly Gln Ala Val Glu Leu Phe Asp Glu Glu
                 245                 250                 255

 ttc cgc cac ctc tac gcc tcc tcc aag cct gtg atg ggc ctg aag tcc      816
 Phe Arg His Leu Tyr Ala Ser Ser Lys Pro Val Met Gly Leu Lys Ser
             260                 265                 270

 ccg cgg ctg gtc gcc ccc gtc ccg ccc gga gca gcc ccg gcc aat ggc      864
 Pro Arg Leu Val Ala Pro Val Pro Pro Gly Ala Ala Pro Ala Asn Gly
         275                 280                 285

 cgc ctt agc agc agc agt ggc tcc gcc agt gac cgc acg tcc tcc aac      912
 Arg Leu Ser Ser Ser Ser Gly Ser Ala Ser Asp Arg Thr Ser Ser Asn
     290                 295                 300

 ccc ttc agc ggc cgc tcg gca ggc agc cac ccc ggt acc cga agt gtg      960
 Pro Phe Ser Gly Arg Ser Ala Gly Ser His Pro Gly Thr Arg Ser Val
 305                 310                 315                 320

 tcc gcg tct tca ggg ccc tgt agc ccc gcg gcc cca cac ccg cct cca     1008
 Ser Ala Ser Ser Gly Pro Cys Ser Pro Ala Ala Pro His Pro Pro Pro
                 325                 330                 335

 ccg ccc cgg ttc cag ccc cac caa ggc cct tgg gga gcc ccg agt ccc     1056
 Pro Pro Arg Phe Gln Pro His Gln Gly Pro Trp Gly Ala Pro Ser Pro
             340                 345                 350

 cag gcc cac ctc tcc ccg cgg ccc cac gac ggc ccg ccc gcc gct gtc     1104
 Gln Ala His Leu Ser Pro Arg Pro His Asp Gly Pro Pro Ala Ala Val
         355                 360                 365

 tac agc aac ctg ggg gcc tac agg ccc acg cgg ctg cag ctg gag cag     1152
 Tyr Ser Asn Leu Gly Ala Tyr Arg Pro Thr Arg Leu Gln Leu Glu Gln
     370                 375                 380

 ctg ggc ctg gtg ccg agg ctg act cca acc tgg agg ccc ttc ctg cag     1200
 Leu Gly Leu Val Pro Arg Leu Thr Pro Thr Trp Arg Pro Phe Leu Gln
 385                 390                 395                 400

 gcc tcc cct cac ttc tga                                             1218
 Ala Ser Pro His Phe 
                 405





      <210> 262
      <211> 1164
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1164)

      <400> 262
  atg agc cac tgt gcc cgg cca tat ctg gta ctg ctg ccc gtg aat ttc      48
  Met Ser His Cys Ala Arg Pro Tyr Leu Val Leu Leu Pro Val Asn Phe
    1               5                  10                  15

 ctt ttc cta gcc ttc ttt atc ctg agt cct ctc acc caa gat cta gct       96
 Leu Phe Leu Ala Phe Phe Ile Leu Ser Pro Leu Thr Gln Asp Leu Ala
              20                  25                  30

 cag atc atg atg att aat aaa gtt ggg ata aat gtt act tac ata aag      144
 Gln Ile Met Met Ile Asn Lys Val Gly Ile Asn Val Thr Tyr Ile Lys
          35                  40                  45

 gag agg att cta gat ccc agc ccg ggg ggg gtt ccg aaa atg ccg cca      192
 Glu Arg Ile Leu Asp Pro Ser Pro Gly Gly Val Pro Lys Met Pro Pro
      50                  55                  60

 gcc tgg agc ggg gaa tcc atg gac cgt ggg gtt gtg ggg ttg ggg agc      240
 Ala Trp Ser Gly Glu Ser Met Asp Arg Gly Val Val Gly Leu Gly Ser
  65                  70                  75                  80

 acg aaa acc cag aga ggg gct aga gct cca cct ccc cag acc gcc gag      288
 Thr Lys Thr Gln Arg Gly Ala Arg Ala Pro Pro Pro Gln Thr Ala Glu
                  85                  90                  95

 ggg cga gag ggc gcg ccg ggg gcc gtg gtt gcc atg gct cct gac tgt      336
 Gly Arg Glu Gly Ala Pro Gly Ala Val Val Ala Met Ala Pro Asp Cys
             100                 105                 110

 ttc aaa cat gat ttc ttt cgg tat act atc ttt gac agt agt gag aaa      384
 Phe Lys His Asp Phe Phe Arg Tyr Thr Ile Phe Asp Ser Ser Glu Lys
         115                 120                 125

 aca aga gat gcc tct gcc gtc ata ctc caa ggt ggg aaa cag agg act      432
 Thr Arg Asp Ala Ser Ala Val Ile Leu Gln Gly Gly Lys Gln Arg Thr
     130                 135                 140

 agc acc tcc aga aga ggg cct ctg gct tct ggg agc ttg agt ata ttt      480
 Ser Thr Ser Arg Arg Gly Pro Leu Ala Ser Gly Ser Leu Ser Ile Phe
 145                 150                 155                 160

 aag ccc aga tct aca cag tac tca cag ggc agg att cac acg ttt aag      528
 Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys
                 165                 170                 175

 cct aga tct aca cag tac tca cag ggc agg att cac acg ttt aag cct      576
 Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro
             180                 185                 190

 aga tct aca cag tac tca cag ggc agg att cac acg ttt aag cct aga      624
 Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg
         195                 200                 205

 tct aca cag tac tca cag ggc agg att cac acg ttt aag cct aga tct      672
 Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser
     210                 215                 220

 aca cag tac tca cag ggc agg att cac acg ttt aag cct aga tct aca      720
 Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr
 225                 230                 235                 240

 cag tac tca cag ggc agg att cac acg ttt aag cct aga tct aca cag      768
 Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln
                 245                 250                 255

 tac tca cag ggc agg att cac acg ttt aag cct aga tct aca cag tac      816
 Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr
             260                 265                 270

 tca cag ggc agg att cac acg ttt aag cct aga tct aca cag tac tca      864
 Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser
         275                 280                 285

 cag ggc agg att cac acg ttt aag cct aga tct aca cag tac tca cag      912
 Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln
     290                 295                 300

 ggc agg att cac acg ttt aag ccc aga tct aca cag tac tca cag ggc      960
 Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly
 305                 310                 315                 320

 agg att cac acg ttt aag ccc aga tct aca cag tac tca cag ggc agg     1008
 Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg
                 325                 330                 335

 att cac acg ttt aag cct aga tct aca cag tac tca cag ggc agg att     1056
 Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile
             340                 345                 350

 cac acg ttt aag cct aga tct aca cag tac tta cag ggc agg att cac     1104
 His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Leu Gln Gly Arg Ile His
         355                 360                 365

 acg ttt aag cct aga tct aca cag tac tca cag ggc agg att cac aca     1152
 Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr
     370                 375                 380

 ttt aaa tgc taa                                                     1164
 Phe Lys Cys 
 385





      <210> 263
      <211> 1152
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1152)

      <400> 263
  atg gta gtg tgt cag cta agt aca gtg tgg atc ctg gac tgg gcc cag      48
  Met Val Val Cys Gln Leu Ser Thr Val Trp Ile Leu Asp Trp Ala Gln
    1               5                  10                  15

 cag cag acg ggc tct gat tcc aag agt gtg gag ata atg ggt gag gca       96
 Gln Gln Thr Gly Ser Asp Ser Lys Ser Val Glu Ile Met Gly Glu Ala
              20                  25                  30

 gcc att cgc ttc agg tca gca gag aaa gtt cag tgc gcc ccc acc agt      144
 Ala Ile Arg Phe Arg Ser Ala Glu Lys Val Gln Cys Ala Pro Thr Ser
          35                  40                  45

 ccc aca gtg cac cag gtc ctg gag agc cgc ccc tgc ccc atc ggg ccc      192
 Pro Thr Val His Gln Val Leu Glu Ser Arg Pro Cys Pro Ile Gly Pro
      50                  55                  60

 acc tgg gcc tct tat tcc tgc tcc ccg gcc tgc cca gct ttt ctg ggc      240
 Thr Trp Ala Ser Tyr Ser Cys Ser Pro Ala Cys Pro Ala Phe Leu Gly
  65                  70                  75                  80

 aaa ccc tgg agc ggc gag ggc ggc gtc caa ctt cct gac cct ggg tct      288
 Lys Pro Trp Ser Gly Glu Gly Gly Val Gln Leu Pro Asp Pro Gly Ser
                  85                  90                  95

 ggc ttt act cct ctg ggg ttt gga att tgc cac cga gaa agc agg aag      336
 Gly Phe Thr Pro Leu Gly Phe Gly Ile Cys His Arg Glu Ser Arg Lys
             100                 105                 110

 ggt cca gtc cag ctc cca tcc aca cgg aag gaa aag gat gaa caa act      384
 Gly Pro Val Gln Leu Pro Ser Thr Arg Lys Glu Lys Asp Glu Gln Thr
         115                 120                 125

 gaa aat caa caa ctc ttc ttc atc cgt cag aga act gag tca cca ggc      432
 Glu Asn Gln Gln Leu Phe Phe Ile Arg Gln Arg Thr Glu Ser Pro Gly
     130                 135                 140

 aaa gca cgg ccc cca aat ctg gag aca cag aca agc ggg ttc caa gaa      480
 Lys Ala Arg Pro Pro Asn Leu Glu Thr Gln Thr Ser Gly Phe Gln Glu
 145                 150                 155                 160

 cct cag ctg aca gga gca gaa cct ctg cgg ggc caa tgc cac gga ctt      528
 Pro Gln Leu Thr Gly Ala Glu Pro Leu Arg Gly Gln Cys His Gly Leu
                 165                 170                 175

 gag ctg ccc ctc atg aat ttc tgg aga tgc cac ctg gac aac ctc cag      576
 Glu Leu Pro Leu Met Asn Phe Trp Arg Cys His Leu Asp Asn Leu Gln
             180                 185                 190

 gca gaa gcc gct gct gac ggg gag agt ctg gta tgt agc tgc tat cag      624
 Ala Glu Ala Ala Ala Asp Gly Glu Ser Leu Val Cys Ser Cys Tyr Gln
         195                 200                 205

 ctt cca gaa acg ctg gaa gga agg gcg ttg ctt tgg cag gac acg tgg      672
 Leu Pro Glu Thr Leu Glu Gly Arg Ala Leu Leu Trp Gln Asp Thr Trp
     210                 215                 220

 gga gat ggg ctg gga ggg gag atc ccg gag gtt cag gga gca agt ttc      720
 Gly Asp Gly Leu Gly Gly Glu Ile Pro Glu Val Gln Gly Ala Ser Phe
 225                 230                 235                 240

 cga ggt tgg aaa gaa gtg act tca ctg ttt aac aaa gat gat gag cag      768
 Arg Gly Trp Lys Glu Val Thr Ser Leu Phe Asn Lys Asp Asp Glu Gln
                 245                 250                 255

 cat ctc ctg gaa aga tgt aaa tct ccc aag tcc aaa gga act aac tta      816
 His Leu Leu Glu Arg Cys Lys Ser Pro Lys Ser Lys Gly Thr Asn Leu
             260                 265                 270

 cga tta aaa gaa gag ttg aag gca gag aag aaa tct gga ttt tgg gac      864
 Arg Leu Lys Glu Glu Leu Lys Ala Glu Lys Lys Ser Gly Phe Trp Asp
         275                 280                 285

 aat ttg gtt tta aaa cag aat ata cag tct aaa aaa cca gat gaa att      912
 Asn Leu Val Leu Lys Gln Asn Ile Gln Ser Lys Lys Pro Asp Glu Ile
     290                 295                 300

 gaa ggt tgg gag cct cca aaa ctt gct ctt gaa gac ata tcg gct gac      960
 Glu Gly Trp Glu Pro Pro Lys Leu Ala Leu Glu Asp Ile Ser Ala Asp
 305                 310                 315                 320

 cct gag gac acc gtg ggt ggc cac cca tcc tgg tca ggc tgg gag gat     1008
 Pro Glu Asp Thr Val Gly Gly His Pro Ser Trp Ser Gly Trp Glu Asp
                 325                 330                 335

 gac gcc aag ggc tcg acc aag tac acc agc ctg gcc agc tct gcc aac     1056
 Asp Ala Lys Gly Ser Thr Lys Tyr Thr Ser Leu Ala Ser Ser Ala Asn
             340                 345                 350

 agc tcc agg tgg agc ctg cgc gcg gca ggg agg ctg gtg agc atc cga     1104
 Ser Ser Arg Trp Ser Leu Arg Ala Ala Gly Arg Leu Val Ser Ile Arg
         355                 360                 365

 cgg cag agt aaa ggc cac ctg aca gat agc ccg gag gag gcg gag tga     1152
 Arg Gln Ser Lys Gly His Leu Thr Asp Ser Pro Glu Glu Ala Glu 
     370                 375                 380





      <210> 264
      <211> 234
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(234)

      <400> 264
  atg ctg ctg gcc agc ctg tgg ggc ctc tcc tgc aag tgg tgc tgt gtc      48
  Met Leu Leu Ala Ser Leu Trp Gly Leu Ser Cys Lys Trp Cys Cys Val
    1               5                  10                  15

 agg gcc aaa gaa cgg cag cat atc acg gag ctg caa aca cct gaa cac       96
 Arg Ala Lys Glu Arg Gln His Ile Thr Glu Leu Gln Thr Pro Glu His
              20                  25                  30

 agc gaa cct gaa ggt ata ggg cat ctt cag gct gct act gag gcg gtc      144
 Ser Glu Pro Glu Gly Ile Gly His Leu Gln Ala Ala Thr Glu Ala Val
          35                  40                  45

 ctg ccg cac tca acc cag aac ctc atc act aaa agg aac ctc atg gtt      192
 Leu Pro His Ser Thr Gln Asn Leu Ile Thr Lys Arg Asn Leu Met Val
      50                  55                  60

 cag gta aca caa tcc ttc aag gtg gca ttc ttc cat ggc taa              234
 Gln Val Thr Gln Ser Phe Lys Val Ala Phe Phe His Gly 
  65                  70                  75





      <210> 265
      <211> 912
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(912)

      <400> 265
  atg gct gtg gtt gca gtg acc gtg gct gtg gcc gtg gct gtg gcc atg      48
  Met Ala Val Val Ala Val Thr Val Ala Val Ala Val Ala Val Ala Met
    1               5                  10                  15

 tca gtg gtg gtg gct gtg gct gtg gct ggg ggg tgg gtg gcc atg gct       96
 Ser Val Val Val Ala Val Ala Val Ala Gly Gly Trp Val Ala Met Ala
              20                  25                  30

 gcg gcc gtg gct gta gtt gtg tct acg gct ggg gtt gtg gct gag gtg      144
 Ala Ala Val Ala Val Val Val Ser Thr Ala Gly Val Val Ala Glu Val
          35                  40                  45

 agc act atc ccc tcc cct ccc cac agg tca gca cta tcc cct ccc ctc      192
 Ser Thr Ile Pro Ser Pro Pro His Arg Ser Ala Leu Ser Pro Pro Leu
      50                  55                  60

 ccc ctc ccc aca ggt cag cac tat ccc ctc ccc ctc ccc aca gtg gaa      240
 Pro Leu Pro Thr Gly Gln His Tyr Pro Leu Pro Leu Pro Thr Val Glu
  65                  70                  75                  80

 ggt gcc ccc ggc cag cgc tgt gac cag cat gtg atg ggt cat ggc ctg      288
 Gly Ala Pro Gly Gln Arg Cys Asp Gln His Val Met Gly His Gly Leu
                  85                  90                  95

 ctg act gcg agc gga ctc ggc ctc tcg cgg gtg ggc cca cca gcc gtg      336
 Leu Thr Ala Ser Gly Leu Gly Leu Ser Arg Val Gly Pro Pro Ala Val
             100                 105                 110

 cag tgt gga aag gta ggc acg tcc atc cta act gcc gtg ggg gca aga      384
 Gln Cys Gly Lys Val Gly Thr Ser Ile Leu Thr Ala Val Gly Ala Arg
         115                 120                 125

 cct gga agc gac aag ctc ttc ctc agt ggc cac aag cgg acc cag acc      432
 Pro Gly Ser Asp Lys Leu Phe Leu Ser Gly His Lys Arg Thr Gln Thr
     130                 135                 140

 ttg gag ctc aag gaa aca ttt ggg ccc aag tcc tgc aaa ggc agc ttc      480
 Leu Glu Leu Lys Glu Thr Phe Gly Pro Lys Ser Cys Lys Gly Ser Phe
 145                 150                 155                 160

 gaa tgc aaa gat cta ggc acc act cct gac agg ctc cac cct gcc cag      528
 Glu Cys Lys Asp Leu Gly Thr Thr Pro Asp Arg Leu His Pro Ala Gln
                 165                 170                 175

 cgg gga gaa acg cag agg cca cag ccg ctg agg aca cgg gcc agc ggc      576
 Arg Gly Glu Thr Gln Arg Pro Gln Pro Leu Arg Thr Arg Ala Ser Gly
             180                 185                 190

 tct cgc ggg tcc cga tcc gtc ctg cag agc atc tct gcc ggt ttc tct      624
 Ser Arg Gly Ser Arg Ser Val Leu Gln Ser Ile Ser Ala Gly Phe Ser
         195                 200                 205

 cca gcc aca gtc tcg ctc ttc tcg tcc cct ccc tcc ccc tcc cct ccc      672
 Pro Ala Thr Val Ser Leu Phe Ser Ser Pro Pro Ser Pro Ser Pro Pro
     210                 215                 220

 cct ccc aca ccc cag ctg gaa cag aat aac aac agg gcg ctg gca agc      720
 Pro Pro Thr Pro Gln Leu Glu Gln Asn Asn Asn Arg Ala Leu Ala Ser
 225                 230                 235                 240

 cgc agg aac tgc aca gac atc tcc agg acc gag gcc atg tcc tcc cgc      768
 Arg Arg Asn Cys Thr Asp Ile Ser Arg Thr Glu Ala Met Ser Ser Arg
                 245                 250                 255

 cgg cca tcg aac tgg ggc agc agg gcc cgc aga cgc tca cag ctc aac      816
 Arg Pro Ser Asn Trp Gly Ser Arg Ala Arg Arg Arg Ser Gln Leu Asn
             260                 265                 270

 gac atc cgc ttc ctg gtt ccg gtc aag aaa caa ata cct ctg ggc cct      864
 Asp Ile Arg Phe Leu Val Pro Val Lys Lys Gln Ile Pro Leu Gly Pro
         275                 280                 285

 cct gcc ctc ccc gag aag gga cag caa ctg cta gaa cct gcc aga tag      912
 Pro Ala Leu Pro Glu Lys Gly Gln Gln Leu Leu Glu Pro Ala Arg 
     290                 295                 300





      <210> 266
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 266
  atg gcg cgc agt gtg cag tgg atg gga aga acc aga ttt atc ccc gtt      48
  Met Ala Arg Ser Val Gln Trp Met Gly Arg Thr Arg Phe Ile Pro Val
    1               5                  10                  15

 ttc caa aca att cct att ggc tca aac att ctg ctt cgg aag ccc tat       96
 Phe Gln Thr Ile Pro Ile Gly Ser Asn Ile Leu Leu Arg Lys Pro Tyr
              20                  25                  30

 tct gac ttg gca ggc cta tgg cag tct gtt aac ttg act ttc cgc ttc      144
 Ser Asp Leu Ala Gly Leu Trp Gln Ser Val Asn Leu Thr Phe Arg Phe
          35                  40                  45

 gtg aga ggc tta ggc tcg gat aac ccg tta gta acc atg cag aga tcc      192
 Val Arg Gly Leu Gly Ser Asp Asn Pro Leu Val Thr Met Gln Arg Ser
      50                  55                  60

 ttc tat ggc att ctc ttt cca aag gcc tct gtt ctc ttt gca taa          237
 Phe Tyr Gly Ile Leu Phe Pro Lys Ala Ser Val Leu Phe Ala 
  65                  70                  75





      <210> 267
      <211> 969
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(969)

      <400> 267
  atg ctg gca ggc gcg ggg act ctg tgc cct tgg ctg gct gtg ttt gcc      48
  Met Leu Ala Gly Ala Gly Thr Leu Cys Pro Trp Leu Ala Val Phe Ala
    1               5                  10                  15

 ccg ctg tgg tgg ctg ggg gcc ccc act ctg tcc tca cgc tcc ctc tgc       96
 Pro Leu Trp Trp Leu Gly Ala Pro Thr Leu Ser Ser Arg Ser Leu Cys
              20                  25                  30

 ttt tgc cct ggc ctg gcg tcc atc agc acc cag gca ctg tcc act ctg      144
 Phe Cys Pro Gly Leu Ala Ser Ile Ser Thr Gln Ala Leu Ser Thr Leu
          35                  40                  45

 cag ctg gcc ctg tgg cct agc caa gag ccc aca gtt gtc cat ccc ctc      192
 Gln Leu Ala Leu Trp Pro Ser Gln Glu Pro Thr Val Val His Pro Leu
      50                  55                  60

 tgc gga gag ccc agc tgc cgt cca tgc acc cct tcc aca gac act gac      240
 Cys Gly Glu Pro Ser Cys Arg Pro Cys Thr Pro Ser Thr Asp Thr Asp
  65                  70                  75                  80

 cac aaa gct tct ccc cgt aag gcc ccg gaa tct gat cag gac cct ccg      288
 His Lys Ala Ser Pro Arg Lys Ala Pro Glu Ser Asp Gln Asp Pro Pro
                  85                  90                  95

 agg gaa cct gcc aag aac aca gat gcc tgg ctt ccc cct ggg tca cca      336
 Arg Glu Pro Ala Lys Asn Thr Asp Ala Trp Leu Pro Pro Gly Ser Pro
             100                 105                 110

 aat cta gcc cac agc gag aac tgg ccg gtg cca ctt act gat gtg ccc      384
 Asn Leu Ala His Ser Glu Asn Trp Pro Val Pro Leu Thr Asp Val Pro
         115                 120                 125

 aag gga ctc agc gtg gta gag tat gag gac ccg ggg gat ggc tgc tgg      432
 Lys Gly Leu Ser Val Val Glu Tyr Glu Asp Pro Gly Asp Gly Cys Trp
     130                 135                 140

 gac tcc cag aga tgg act ctc acg gct tcc agg ggt gca aag gaa gga      480
 Asp Ser Gln Arg Trp Thr Leu Thr Ala Ser Arg Gly Ala Lys Glu Gly
 145                 150                 155                 160

 cag tgt gga gtg tgc tgt aag ccc caa ccg aca ctg ctt gag cac ctg      528
 Gln Cys Gly Val Cys Cys Lys Pro Gln Pro Thr Leu Leu Glu His Leu
                 165                 170                 175

 ctg tat act aag cgc ttt cat aca gtg aag gcg agg ctg cag gcc atg      576
 Leu Tyr Thr Lys Arg Phe His Thr Val Lys Ala Arg Leu Gln Ala Met
             180                 185                 190

 tcc agc tca cag aca gag aca cca agg cca ccc agg cac caa ggt gat      624
 Ser Ser Ser Gln Thr Glu Thr Pro Arg Pro Pro Arg His Gln Gly Asp
         195                 200                 205

 gca gct acc gag gcc aca cga gaa gca aga ggg cat ctc tgt ggc aga      672
 Ala Ala Thr Glu Ala Thr Arg Glu Ala Arg Gly His Leu Cys Gly Arg
     210                 215                 220

 cct aga gct gag gac ccc cag agg tgt ctg ccc acg tcg ctg gcc cag      720
 Pro Arg Ala Glu Asp Pro Gln Arg Cys Leu Pro Thr Ser Leu Ala Gln
 225                 230                 235                 240

 tgt gtt ctc tac ccg gcc tat ccc ttg gcc aat gtg ctc tcc ggt cct      768
 Cys Val Leu Tyr Pro Ala Tyr Pro Leu Ala Asn Val Leu Ser Gly Pro
                 245                 250                 255

 gcc tgg tca aga gtc aca ggc aaa tgg ctc tgg ttg gat ctg aat ccg      816
 Ala Trp Ser Arg Val Thr Gly Lys Trp Leu Trp Leu Asp Leu Asn Pro
             260                 265                 270

 ggc cag cct tcc aaa tta tca ccc gac gtc acc atc atg cag gtc aaa      864
 Gly Gln Pro Ser Lys Leu Ser Pro Asp Val Thr Ile Met Gln Val Lys
         275                 280                 285

 gaa gtt tta ggg aaa ata aaa gat tat cta aaa cgg atg aag att aag      912
 Glu Val Leu Gly Lys Ile Lys Asp Tyr Leu Lys Arg Met Lys Ile Lys
     290                 295                 300

 ctg gaa aac atg atg atg tca agg gaa ggc cca ggt gcc ccc gac cgg      960
 Leu Glu Asn Met Met Met Ser Arg Glu Gly Pro Gly Ala Pro Asp Arg
 305                 310                 315                 320

 cgc cct tga                                                          969
 Arg Pro 






      <210> 268
      <211> 825
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(825)

      <400> 268
  atg aga ggc gct cgc ggc gcc tgg gat ttt ctc tgc gtt ctg ctc cta      48
  Met Arg Gly Ala Arg Gly Ala Trp Asp Phe Leu Cys Val Leu Leu Leu
    1               5                  10                  15

 ctg ctt cgc gtc cag aca ggt ggg aca ccg cgg ctg gca ccc cga ccg       96
 Leu Leu Arg Val Gln Thr Gly Gly Thr Pro Arg Leu Ala Pro Arg Pro
              20                  25                  30

 tgc gac tac tcg gcg aag cct gtg cct ggg agg gtg gta ccc gcc agg      144
 Cys Asp Tyr Ser Ala Lys Pro Val Pro Gly Arg Val Val Pro Ala Arg
          35                  40                  45

 gtg cat ccg gag aga gga ctg cgg gcc ctc agt gcc cgt gcg ttc cag      192
 Val His Pro Glu Arg Gly Leu Arg Ala Leu Ser Ala Arg Ala Phe Gln
      50                  55                  60

 cct ccg ggg aga ctc cag gtg gcc ctc gga ctc tcc ggc gcc ctg cct      240
 Pro Pro Gly Arg Leu Gln Val Ala Leu Gly Leu Ser Gly Ala Leu Pro
  65                  70                  75                  80

 cgc tca cct gcg cga gga gac ccc agc tgc tgg tgg tgg ggg acg cga      288
 Arg Ser Pro Ala Arg Gly Asp Pro Ser Cys Trp Trp Trp Gly Thr Arg
                  85                  90                  95

 atc cgg ggt tct tcg gga atg ggg aca gca aga ggg gaa ttg aag gtc      336
 Ile Arg Gly Ser Ser Gly Met Gly Thr Ala Arg Gly Glu Leu Lys Val
             100                 105                 110

 atg gcc cct gta gat gag gcc tgt gct ctt cag gtt gca tta ggc tct      384
 Met Ala Pro Val Asp Glu Ala Cys Ala Leu Gln Val Ala Leu Gly Ser
         115                 120                 125

 agg gct tta tcc tgc cat ccc tta ggc att ccc cac tgg gcc ctg aat      432
 Arg Ala Leu Ser Cys His Pro Leu Gly Ile Pro His Trp Ala Leu Asn
     130                 135                 140

 aaa atg gcc ata ctg ggt ata gag gag gac ata gaa ttg acg aaa gct      480
 Lys Met Ala Ile Leu Gly Ile Glu Glu Asp Ile Glu Leu Thr Lys Ala
 145                 150                 155                 160

 ttg gga aat agg tcc ttt gaa agc aac tta aag aaa ttg gat tta tta      528
 Leu Gly Asn Arg Ser Phe Glu Ser Asn Leu Lys Lys Leu Asp Leu Leu
                 165                 170                 175

 agc ctg gag aag ata agt ctt tat atc atg gct ttc ctg gca ttt tgg      576
 Ser Leu Glu Lys Ile Ser Leu Tyr Ile Met Ala Phe Leu Ala Phe Trp
             180                 185                 190

 ttt tct gaa acg cac cct cta ata gat gcc tta tgg gaa gta gtt cct      624
 Phe Ser Glu Thr His Pro Leu Ile Asp Ala Leu Trp Glu Val Val Pro
         195                 200                 205

 gaa tta tat gtc cac aac ggc gag tgt gta gtc tgt ata ttt aaa ggt      672
 Glu Leu Tyr Val His Asn Gly Glu Cys Val Val Cys Ile Phe Lys Gly
     210                 215                 220

 cag ggc tgt gtg gaa gaa cac aga ctg tcc agg gag gat att tgc tgt      720
 Gln Gly Cys Val Glu Glu His Arg Leu Ser Arg Glu Asp Ile Cys Cys
 225                 230                 235                 240

 ttt tca ctc act aca aat ggc agc tca gag gat ctc act gga tta gta      768
 Phe Ser Leu Thr Thr Asn Gly Ser Ser Glu Asp Leu Thr Gly Leu Val
                 245                 250                 255

 tgg gct gtg gat gtg ggc tcc ggg ctc tca gat gta gtg cac cag att      816
 Trp Ala Val Asp Val Gly Ser Gly Leu Ser Asp Val Val His Gln Ile
             260                 265                 270

 gag gtc tga                                                          825
 Glu Val 






      <210> 269
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 269
  atg cgg ccc gct gtc cgg gcg gct ggc cac gtg gat gcg gta ctg gcc      48
  Met Arg Pro Ala Val Arg Ala Ala Gly His Val Asp Ala Val Leu Ala
    1               5                  10                  15

 acc atc ctc ctc gta gca ctg ctc gcg cag gct ggt gat gag gtt gtc       96
 Thr Ile Leu Leu Val Ala Leu Leu Ala Gln Ala Gly Asp Glu Val Val
              20                  25                  30

 cac cag gcc ctc gat gtt ctc ctc cag cat gct gga ctc gtc cag ccg      144
 His Gln Ala Leu Asp Val Leu Leu Gln His Ala Gly Leu Val Gln Pro
          35                  40                  45

 cgc cgt gcc gca ctc ata gca cag ctg ctt gaa gac gcg cat gcg cac      192
 Arg Arg Ala Ala Leu Ile Ala Gln Leu Leu Glu Asp Ala His Ala His
      50                  55                  60

 cga gcc cgc ccg ctg ggc gcg gtc cag gaa cat gtg gaa gag gat gac      240
 Arg Ala Arg Pro Leu Gly Ala Val Gln Glu His Val Glu Glu Asp Asp
  65                  70                  75                  80

 cac atg ggc aga ctg cca ggc tat ggg ata gag gtg agg cca agc ctg      288
 His Met Gly Arg Leu Pro Gly Tyr Gly Ile Glu Val Arg Pro Ser Leu
                  85                  90                  95

 gct ctg acc cct gaa agc ctg atc aca tga                              318
 Ala Leu Thr Pro Glu Ser Leu Ile Thr 
             100                 105





      <210> 270
      <211> 813
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(813)

      <400> 270
  atg gat tca atc act ctg aca act cag aac atc ttc aca agc atg ata      48
  Met Asp Ser Ile Thr Leu Thr Thr Gln Asn Ile Phe Thr Ser Met Ile
    1               5                  10                  15

 gct att tcc aca cca ctg gcc tgg gtc cag tca aca cag ccc aat aag       96
 Ala Ile Ser Thr Pro Leu Ala Trp Val Gln Ser Thr Gln Pro Asn Lys
              20                  25                  30

 tct tct gca gtg agt tgg tcc cgc gta ggc gcg cag ctc cgg acc ccg      144
 Ser Ser Ala Val Ser Trp Ser Arg Val Gly Ala Gln Leu Arg Thr Pro
          35                  40                  45

 ctt ctg ctt ctg ctc ctg ctc cta ctc ctc ctg ggc acc acc gga cag      192
 Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Gly Thr Thr Gly Gln
      50                  55                  60

 tgc tct gac ccg cag ccc aac cgc cgg ggt gcc gac ccg cgg gga ccc      240
 Cys Ser Asp Pro Gln Pro Asn Arg Arg Gly Ala Asp Pro Arg Gly Pro
  65                  70                  75                  80

 acc cct ttg tcc ctc ctc ccg cgg cgg cgg cgg cgt cag ccc gcc ccc      288
 Thr Pro Leu Ser Leu Leu Pro Arg Arg Arg Arg Arg Gln Pro Ala Pro
                  85                  90                  95

 gac ccg agc gtg gcg cct ccg cgc tgg ccg ccc ggc ccg gga aac tgt      336
 Asp Pro Ser Val Ala Pro Pro Arg Trp Pro Pro Gly Pro Gly Asn Cys
             100                 105                 110

 caa att ggc cgc tac cac cca cgc gcc tgc cgg gga agg gct cgc cgg      384
 Gln Ile Gly Arg Tyr His Pro Arg Ala Cys Arg Gly Arg Ala Arg Arg
         115                 120                 125

 cgc cgc gcc ttc gag gct cct gcg gcg aac cgc gtc acg cgc gac tcc      432
 Arg Arg Ala Phe Glu Ala Pro Ala Ala Asn Arg Val Thr Arg Asp Ser
     130                 135                 140

 tgg ccg ggg gcg gga ggc ggc ggc ggc ggc agg aga agc cca agg ccc      480
 Trp Pro Gly Ala Gly Gly Gly Gly Gly Gly Arg Arg Ser Pro Arg Pro
 145                 150                 155                 160

 gag cgg ccc gca gcc ccc acg cct gca ccc ctc cac ccc cgc cag ccc      528
 Glu Arg Pro Ala Ala Pro Thr Pro Ala Pro Leu His Pro Arg Gln Pro
                 165                 170                 175

 gat ggt tcg ctc cgc ggc gtg cac tgg agc aag cag gtc ccg ctc cga      576
 Asp Gly Ser Leu Arg Gly Val His Trp Ser Lys Gln Val Pro Leu Arg
             180                 185                 190

 gcg cgc gcg ctc tgg gaa gtg ctg caa gtt tgg aga cct gga gtg agc      624
 Ala Arg Ala Leu Trp Glu Val Leu Gln Val Trp Arg Pro Gly Val Ser
         195                 200                 205

 tcc ggg cgc tgc tgg ccc gac tgt ccg cgg tgt ttc ccc ggt agc ctc      672
 Ser Gly Arg Cys Trp Pro Asp Cys Pro Arg Cys Phe Pro Gly Ser Leu
     210                 215                 220

 atc tcc tct cct ggc tcc acc cat ctt cct cag tcc aaa cac cag tta      720
 Ile Ser Ser Pro Gly Ser Thr His Leu Pro Gln Ser Lys His Gln Leu
 225                 230                 235                 240

 aca ata acc acc cgg ttc acc tgc agg ctt cct ccc aca ata atc acc      768
 Thr Ile Thr Thr Arg Phe Thr Cys Arg Leu Pro Pro Thr Ile Ile Thr
                 245                 250                 255

 cca ctc aat ggc ccc tgt gat tac ctc cag gag agc ggc atc taa          813
 Pro Leu Asn Gly Pro Cys Asp Tyr Leu Gln Glu Ser Gly Ile 
             260                 265                 270





      <210> 271
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 271
  atg gcc aga tgt gtg att ata tat tgg ttc tgg gct gta gcc agt ggt      48
  Met Ala Arg Cys Val Ile Ile Tyr Trp Phe Trp Ala Val Ala Ser Gly
    1               5                  10                  15

 ttg gtt gga tgg tca ggg act tgg aag aag cat gat tgg aaa att ggt       96
 Leu Val Gly Trp Ser Gly Thr Trp Lys Lys His Asp Trp Lys Ile Gly
              20                  25                  30

 gac aag gaa atc cgg gga aga ggt atg tgg atg gac ctc tct gag tgg      144
 Asp Lys Glu Ile Arg Gly Arg Gly Met Trp Met Asp Leu Ser Glu Trp
          35                  40                  45

 tca aaa act gtg aag ata ttt gta tcc ctt gtg agt gtt cac caa agg      192
 Ser Lys Thr Val Lys Ile Phe Val Ser Leu Val Ser Val His Gln Arg
      50                  55                  60

 gtg acc tca gca gag gag gat ttt gat agt caa gtg gat agg atg act      240
 Val Thr Ser Ala Glu Glu Asp Phe Asp Ser Gln Val Asp Arg Met Thr
  65                  70                  75                  80

 cat tct gtg gac acc act cag cct ctt acc cca gct gcc cct gtc atc      288
 His Ser Val Asp Thr Thr Gln Pro Leu Thr Pro Ala Ala Pro Val Ile
                  85                  90                  95

 acc caa tgg gcg cat gaa caa att ggc cat ggt ggg agg gat gga ggt      336
 Thr Gln Trp Ala His Glu Gln Ile Gly His Gly Gly Arg Asp Gly Gly
             100                 105                 110

 tat gca tgg tct cag caa cat gga ctt aca ttc atc aag gct gac ctg      384
 Tyr Ala Trp Ser Gln Gln His Gly Leu Thr Phe Ile Lys Ala Asp Leu
         115                 120                 125

 gct acg gct att gct gag tgc cca att tac cag cag cac aga cca aaa      432
 Ala Thr Ala Ile Ala Glu Cys Pro Ile Tyr Gln Gln His Arg Pro Lys
     130                 135                 140

 cca agc cct tga                                                      444
 Pro Ser Pro 
 145





      <210> 272
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 272
  atg cta gcc aat cca ctt ttc ttt atc tcc ctg act acc acc ttg gtc      48
  Met Leu Ala Asn Pro Leu Phe Phe Ile Ser Leu Thr Thr Thr Leu Val
    1               5                  10                  15

 cat ccc tgg tct gac aag ccc tgt gtg cct cat ttg ctt cag agg gac       96
 His Pro Trp Ser Asp Lys Pro Cys Val Pro His Leu Leu Gln Arg Asp
              20                  25                  30

 agt tac tat gtt tat acc cag caa gag ctt aaa gag aag ctg tat caa      144
 Ser Tyr Tyr Val Tyr Thr Gln Gln Glu Leu Lys Glu Lys Leu Tyr Gln
          35                  40                  45

 gaa atc ata tca tat ttc gac aaa ggc aaa gtg agt att gga ttg ttt      192
 Glu Ile Ile Ser Tyr Phe Asp Lys Gly Lys Val Ser Ile Gly Leu Phe
      50                  55                  60

 ttg tac tag                                                          201
 Leu Tyr 
  65





      <210> 273
      <211> 339
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(339)

      <400> 273
  atg agg gaa ttg gcc ttg ggc ata tta att ctg agc tca tct ggc agt      48
  Met Arg Glu Leu Ala Leu Gly Ile Leu Ile Leu Ser Ser Ser Gly Ser
    1               5                  10                  15

 tct gct ttg gct ggg gca gtc ttt ggt ggg tca gac cca gtc ggt tct       96
 Ser Ala Leu Ala Gly Ala Val Phe Gly Gly Ser Asp Pro Val Gly Ser
              20                  25                  30

 tgg acc cag ggc tcc aaa gtc tcg aaa gct tca gcc ctc aca agc ctt      144
 Trp Thr Gln Gly Ser Lys Val Ser Lys Ala Ser Ala Leu Thr Ser Leu
          35                  40                  45

 tgt acc aca gac act ggc ccc atg cct ctt act cat ccg aac cac gga      192
 Cys Thr Thr Asp Thr Gly Pro Met Pro Leu Thr His Pro Asn His Gly
      50                  55                  60

 cca gac act cta cag cga tgg aca tcc tcc cag act cca aca tca ctg      240
 Pro Asp Thr Leu Gln Arg Trp Thr Ser Ser Gln Thr Pro Thr Ser Leu
  65                  70                  75                  80

 agt tcc aaa tta aat cct gaa ccc gaa gca gac gcc gca tcg atc cta      288
 Ser Ser Lys Leu Asn Pro Glu Pro Glu Ala Asp Ala Ala Ser Ile Leu
                  85                  90                  95

 atc gcc acc tcc atc ctt tac aag cag agt gat cca tac ctt gac agt      336
 Ile Ala Thr Ser Ile Leu Tyr Lys Gln Ser Asp Pro Tyr Leu Asp Ser
             100                 105                 110

 tag                                                                  339
 






      <210> 274
      <211> 1080
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1080)

      <400> 274
  atg ctc ctg aag tgg ccc tgg gcc gtg gtt ctg gcc agg cag ggt ctc      48
  Met Leu Leu Lys Trp Pro Trp Ala Val Val Leu Ala Arg Gln Gly Leu
    1               5                  10                  15

 tgt gca ctc agg gcc atg cag ggt gct gtc gag gcc cct cgc tca tcg       96
 Cys Ala Leu Arg Ala Met Gln Gly Ala Val Glu Ala Pro Arg Ser Ser
              20                  25                  30

 ccg cgg gcc tat gag ggc cga ctc aag gac cag agg gag ggt ccc cga      144
 Pro Arg Ala Tyr Glu Gly Arg Leu Lys Asp Gln Arg Glu Gly Pro Arg
          35                  40                  45

 gcc ctg ttc tgg gag cca caa gat ttc acg tcc tct gga atc cac aaa      192
 Ala Leu Phe Trp Glu Pro Gln Asp Phe Thr Ser Ser Gly Ile His Lys
      50                  55                  60

 gca ggc ctg ggc agt ccc aga atg ggg ccg tac ctg ggt ctt ccg gat      240
 Ala Gly Leu Gly Ser Pro Arg Met Gly Pro Tyr Leu Gly Leu Pro Asp
  65                  70                  75                  80

 agt caa gaa gta caa gca cct ctg gcc ctc tgg aag cct tta ggg tgg      288
 Ser Gln Glu Val Gln Ala Pro Leu Ala Leu Trp Lys Pro Leu Gly Trp
                  85                  90                  95

 aag cag cag caa cat gaa aag ccg gcc ctg gcc cct ggc ggt cag cgg      336
 Lys Gln Gln Gln His Glu Lys Pro Ala Leu Ala Pro Gly Gly Gln Arg
             100                 105                 110

 ctg gga ccc cgg gat cca gcc ctg gcc ctc ctg aga ggt ttg cct cgt      384
 Leu Gly Pro Arg Asp Pro Ala Leu Ala Leu Leu Arg Gly Leu Pro Arg
         115                 120                 125

 gct ggc cga tat acc aca ctc cct cca gga gga gcc tgg agc tca gcc      432
 Ala Gly Arg Tyr Thr Thr Leu Pro Pro Gly Gly Ala Trp Ser Ser Ala
     130                 135                 140

 aca gtc cgg ctg gtt gtg tgg aga agg gcc cca ggg ccc gtg aac tgg      480
 Thr Val Arg Leu Val Val Trp Arg Arg Ala Pro Gly Pro Val Asn Trp
 145                 150                 155                 160

 aac gaa tca gcc cat cct ttc tcc tca tac cca gct gcc cag cgg atg      528
 Asn Glu Ser Ala His Pro Phe Ser Ser Tyr Pro Ala Ala Gln Arg Met
                 165                 170                 175

 tgg aag aac gga gat gct gga aac tgc aat gcc gga tat ctg gat gac      576
 Trp Lys Asn Gly Asp Ala Gly Asn Cys Asn Ala Gly Tyr Leu Asp Asp
             180                 185                 190

 aca ggc tcc ttc ctg gat gat ctg ctt ctc agc cca tgt ggg gtc ttc      624
 Thr Gly Ser Phe Leu Asp Asp Leu Leu Leu Ser Pro Cys Gly Val Phe
         195                 200                 205

 tcc aaa agc ccc aca aca cca tcc ttc cga ttc ccc atc tgc tcc cga      672
 Ser Lys Ser Pro Thr Thr Pro Ser Phe Arg Phe Pro Ile Cys Ser Arg
     210                 215                 220

 tcc gag gag ctc aca gtt ggg ccg gtg tta tgc ccc agg cct cag gcc      720
 Ser Glu Glu Leu Thr Val Gly Pro Val Leu Cys Pro Arg Pro Gln Ala
 225                 230                 235                 240

 ctg gcc cca gat gca gct gca gag cct gga gct cgg agc tcc ccg gca      768
 Leu Ala Pro Asp Ala Ala Ala Glu Pro Gly Ala Arg Ser Ser Pro Ala
                 245                 250                 255

 cac ctt cag gtc tgg gtg ttc tgt ggc cca cga tcc aat cct cag cac      816
 His Leu Gln Val Trp Val Phe Cys Gly Pro Arg Ser Asn Pro Gln His
             260                 265                 270

 tat gag gcc tgg tct caa ggc gag agg cct ggt atc gga ttt aga cgt      864
 Tyr Glu Ala Trp Ser Gln Gly Glu Arg Pro Gly Ile Gly Phe Arg Arg
         275                 280                 285

 cct ggt ccc agc ctg ctc tgt cgt agc ctt gga gct ggc act gac tca      912
 Pro Gly Pro Ser Leu Leu Cys Arg Ser Leu Gly Ala Gly Thr Asp Ser
     290                 295                 300

 gcg aag agg aaa gga aat tat cca ata gaa atg gaa cgc tct gca gac      960
 Ala Lys Arg Lys Gly Asn Tyr Pro Ile Glu Met Glu Arg Ser Ala Asp
 305                 310                 315                 320

 acc cca gca gca cag agc tgg aac acc aga cac ccc agc ctg gag aag     1008
 Thr Pro Ala Ala Gln Ser Trp Asn Thr Arg His Pro Ser Leu Glu Lys
                 325                 330                 335

 gtg gtt ctg agc tcc cat ggc ccc tct gtg acc ttg tcc acc tat ggc     1056
 Val Val Leu Ser Ser His Gly Pro Ser Val Thr Leu Ser Thr Tyr Gly
             340                 345                 350

 cag tgc ctg tgg tca aag ggc tga                                     1080
 Gln Cys Leu Trp Ser Lys Gly 
         355





      <210> 275
      <211> 477
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(477)

      <400> 275
  atg aca gag aca ctc ttc ctg ctg agg ctc tgc cct ctg ctc cta gat      48
  Met Thr Glu Thr Leu Phe Leu Leu Arg Leu Cys Pro Leu Leu Leu Asp
    1               5                  10                  15

 cca aat ggc atc tcc tac cct atc cct gta tgg ctt aac cta ggg aaa       96
 Pro Asn Gly Ile Ser Tyr Pro Ile Pro Val Trp Leu Asn Leu Gly Lys
              20                  25                  30

 ctc ttt ccc aga gga gtc agg aac act ggg gca cag aaa cac tgg ctc      144
 Leu Phe Pro Arg Gly Val Arg Asn Thr Gly Ala Gln Lys His Trp Leu
          35                  40                  45

 act gaa ggg gca gct aag gaa cac tgt gta agt gat gac tca gag cac      192
 Thr Glu Gly Ala Ala Lys Glu His Cys Val Ser Asp Asp Ser Glu His
      50                  55                  60

 ttt gaa agc tgg agg gca gca cag gtc att tat ttc ccc tgg gtt gcc      240
 Phe Glu Ser Trp Arg Ala Ala Gln Val Ile Tyr Phe Pro Trp Val Ala
  65                  70                  75                  80

 tac act cgc ttc ttc cca ctc ccc tat gaa gga caa tat aag cct ctg      288
 Tyr Thr Arg Phe Phe Pro Leu Pro Tyr Glu Gly Gln Tyr Lys Pro Leu
                  85                  90                  95

 gac ctc act agg tca ggg cat gtc cct gct tgc act atc cat gac act      336
 Asp Leu Thr Arg Ser Gly His Val Pro Ala Cys Thr Ile His Asp Thr
             100                 105                 110

 ttc ctc ttt tac tct tta gca atg agg gaa tgt cat cct tac cca gat      384
 Phe Leu Phe Tyr Ser Leu Ala Met Arg Glu Cys His Pro Tyr Pro Asp
         115                 120                 125

 gcc agc cac ctg tct cac atc cag gac agc gag tct cca tct cct ctc      432
 Ala Ser His Leu Ser His Ile Gln Asp Ser Glu Ser Pro Ser Pro Leu
     130                 135                 140

 cag caa ata ccc att gca cag aga cat acc cct cct tat gaa taa          477
 Gln Gln Ile Pro Ile Ala Gln Arg His Thr Pro Pro Tyr Glu 
 145                 150                 155





      <210> 276
      <211> 519
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(519)

      <400> 276
  atg acc ttt ccc gta gct gta gca cag atg cta tgc cca cat acc aaa      48
  Met Thr Phe Pro Val Ala Val Ala Gln Met Leu Cys Pro His Thr Lys
    1               5                  10                  15

 gcg ctt att ctc tat tac tct ttg agt ttt gca tgt ctt gtg acg ttt       96
 Ala Leu Ile Leu Tyr Tyr Ser Leu Ser Phe Ala Cys Leu Val Thr Phe
              20                  25                  30

 gtg cgt tct tca cag aaa ggg tca ttg gcc atg gta acc aaa aat gta      144
 Val Arg Ser Ser Gln Lys Gly Ser Leu Ala Met Val Thr Lys Asn Val
          35                  40                  45

 aaa ggg aaa agc atg ctg caa aga aaa ctc ctt tct ctg cac tcc act      192
 Lys Gly Lys Ser Met Leu Gln Arg Lys Leu Leu Ser Leu His Ser Thr
      50                  55                  60

 cca ctc tca gcc ttc atc att gct agc cat aca aag cat gta gtc tac      240
 Pro Leu Ser Ala Phe Ile Ile Ala Ser His Thr Lys His Val Val Tyr
  65                  70                  75                  80

 aag att aag gct ctt tta ttt tta agg aat agc aag atg ttc tgg tat      288
 Lys Ile Lys Ala Leu Leu Phe Leu Arg Asn Ser Lys Met Phe Trp Tyr
                  85                  90                  95

 gca aat ata agc aac tct ctg tct acg tca atg cag aac aca gac tca      336
 Ala Asn Ile Ser Asn Ser Leu Ser Thr Ser Met Gln Asn Thr Asp Ser
             100                 105                 110

 gac gaa cca aag cga tcc tat gaa gtg ggt att tta agg ccc act gta      384
 Asp Glu Pro Lys Arg Ser Tyr Glu Val Gly Ile Leu Arg Pro Thr Val
         115                 120                 125

 cag aca aga aag cta agc cat gca gat gtt gat aaa gta gag cta gga      432
 Gln Thr Arg Lys Leu Ser His Ala Asp Val Asp Lys Val Glu Leu Gly
     130                 135                 140

 atc cca ccc aca gtg ggt gga tca ttt tgc aaa gtc aac att aac acc      480
 Ile Pro Pro Thr Val Gly Gly Ser Phe Cys Lys Val Asn Ile Asn Thr
 145                 150                 155                 160

 tgc agc aga aac aaa cat gaa gac aga atc tca gta tag                  519
 Cys Ser Arg Asn Lys His Glu Asp Arg Ile Ser Val 
                 165                 170





      <210> 277
      <211> 402
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(402)

      <400> 277
  atg atg gac tgt ggc ctg cgg ttc atg ggg tgt act att ctg gct ctt      48
  Met Met Asp Cys Gly Leu Arg Phe Met Gly Cys Thr Ile Leu Ala Leu
    1               5                  10                  15

 acc tgt gtt cac gtt gct ccc ctg atg tca gct aca gag cag gaa aca       96
 Thr Cys Val His Val Ala Pro Leu Met Ser Ala Thr Glu Gln Glu Thr
              20                  25                  30

 gga aaa acc acg cat atg att ttc agg cag ctg gag gaa gag gaa gag      144
 Gly Lys Thr Thr His Met Ile Phe Arg Gln Leu Glu Glu Glu Glu Glu
          35                  40                  45

 aat gcc ttc cct gca gtc cct gag aag cca gtt tta caa aca gca aat      192
 Asn Ala Phe Pro Ala Val Pro Glu Lys Pro Val Leu Gln Thr Ala Asn
      50                  55                  60

 atg gtt tgg aac aaa gtt ttg aca ctg act tgg tat ctt gtg ctc ata      240
 Met Val Trp Asn Lys Val Leu Thr Leu Thr Trp Tyr Leu Val Leu Ile
  65                  70                  75                  80

 tta cgt ttg tat gaa tat tcc acc gac ttt tca act cca aag aaa agt      288
 Leu Arg Leu Tyr Glu Tyr Ser Thr Asp Phe Ser Thr Pro Lys Lys Ser
                  85                  90                  95

 ttc cgc tcc aag gct aca ttc aac att cag act att tca act tca gtt      336
 Phe Arg Ser Lys Ala Thr Phe Asn Ile Gln Thr Ile Ser Thr Ser Val
             100                 105                 110

 gct ccc acc cca aca gcg atc ttt gaa act gat atg gcc ctg aaa gaa      384
 Ala Pro Thr Pro Thr Ala Ile Phe Glu Thr Asp Met Ala Leu Lys Glu
         115                 120                 125

 gcc aga ata act ttg taa                                              402
 Ala Arg Ile Thr Leu 
     130





      <210> 278
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 278
  atg ccc tac tgg ttt tct gta act ctg ctt ctt ttg caa ata ttc cct      48
  Met Pro Tyr Trp Phe Ser Val Thr Leu Leu Leu Leu Gln Ile Phe Pro
    1               5                  10                  15

 ctg ttg aat ttt ccc tac att acc ctg cgt gat tgt gcc att ggc cac       96
 Leu Leu Asn Phe Pro Tyr Ile Thr Leu Arg Asp Cys Ala Ile Gly His
              20                  25                  30

 tgc tgg gat gtg aca gaa agg cca ttt gag gat aaa gga cca aag aac      144
 Cys Trp Asp Val Thr Glu Arg Pro Phe Glu Asp Lys Gly Pro Lys Asn
          35                  40                  45

 agc agc ggg gac tca gct tgg cca gtg ctt gtg atg ggc aag cca ggg      192
 Ser Ser Gly Asp Ser Ala Trp Pro Val Leu Val Met Gly Lys Pro Gly
      50                  55                  60

 gca tcc cct tct cat ggg ttg ggt gaa gcc tct agt gct gaa gga caa      240
 Ala Ser Pro Ser His Gly Leu Gly Glu Ala Ser Ser Ala Glu Gly Gln
  65                  70                  75                  80

 agc tca cac aac tcc cca ctt ttg gct gtc agc acc agc cag aca gga      288
 Ser Ser His Asn Ser Pro Leu Leu Ala Val Ser Thr Ser Gln Thr Gly
                  85                  90                  95

 gca aga acc agg aac aac tcc cag cat ctc aga atc aaa tct cca ctc      336
 Ala Arg Thr Arg Asn Asn Ser Gln His Leu Arg Ile Lys Ser Pro Leu
             100                 105                 110

 ctg gat gct cta gtc ttt cct gat tac agg ccc aca tgg agc ctg ttt      384
 Leu Asp Ala Leu Val Phe Pro Asp Tyr Arg Pro Thr Trp Ser Leu Phe
         115                 120                 125

 gaa ggg gtc gct gcc atg ggc tga                                      408
 Glu Gly Val Ala Ala Met Gly 
     130                 135





      <210> 279
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 279
  atg gtc act gtg ctg gtc tgt tgg gcc ctg cag gtt ctc cag ctc tat      48
  Met Val Thr Val Leu Val Cys Trp Ala Leu Gln Val Leu Gln Leu Tyr
    1               5                  10                  15

 cag atc acc cag atc aat cat ggc ctg atg atg gtg ggg ccc tcg gga       96
 Gln Ile Thr Gln Ile Asn His Gly Leu Met Met Val Gly Pro Ser Gly
              20                  25                  30

 agt ggg aag agc atg gcc tgg cgt gtc ctg ctg aag gca ttg gag aga      144
 Ser Gly Lys Ser Met Ala Trp Arg Val Leu Leu Lys Ala Leu Glu Arg
          35                  40                  45

 ctc gag ggt gtg gaa ggt gtg gcc cat atc atc gac ccc aag gcc atc      192
 Leu Glu Gly Val Glu Gly Val Ala His Ile Ile Asp Pro Lys Ala Ile
      50                  55                  60

 agc aaa gac cac ctc tac gga acc ctg gac ccc aac acc agg gaa tgg      240
 Ser Lys Asp His Leu Tyr Gly Thr Leu Asp Pro Asn Thr Arg Glu Trp
  65                  70                  75                  80

 aca gat ggg ctc ttc aca cac gtg ctg aga aag tac gtc ttc ttt gat      288
 Thr Asp Gly Leu Phe Thr His Val Leu Arg Lys Tyr Val Phe Phe Asp
                  85                  90                  95

 ctg tgt ttg tgt tct cct gga tat ggg cgc taa                          321
 Leu Cys Leu Cys Ser Pro Gly Tyr Gly Arg 
             100                 105





      <210> 280
      <211> 156
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(156)

      <400> 280
  atg ctg ctg ctg tca tgg act gtg ctg gag gca agg caa tgg ctt ctg      48
  Met Leu Leu Leu Ser Trp Thr Val Leu Glu Ala Arg Gln Trp Leu Leu
    1               5                  10                  15

 tct acc atg gac gaa gta gcc ttc aag gac aaa gag cag gtc cag tct       96
 Ser Thr Met Asp Glu Val Ala Phe Lys Asp Lys Glu Gln Val Gln Ser
              20                  25                  30

 aca cac agc cct gct cct gag aag cgg aaa gtc aat ggt tct gct ttc      144
 Thr His Ser Pro Ala Pro Glu Lys Arg Lys Val Asn Gly Ser Ala Phe
          35                  40                  45

 cgc caa ccc tga                                                      156
 Arg Gln Pro 
      50





      <210> 281
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 281
  atg gac tgg att caa ctt aga aaa ttc tgg ata ttt ttt agt tgg tgc      48
  Met Asp Trp Ile Gln Leu Arg Lys Phe Trp Ile Phe Phe Ser Trp Cys
    1               5                  10                  15

 acg gag gaa aaa cga agg gat gtg gag ttt agc gac ttg ctg gag aga       96
 Thr Glu Glu Lys Arg Arg Asp Val Glu Phe Ser Asp Leu Leu Glu Arg
              20                  25                  30

 gaa gaa cta tca act gaa ggc tca gtt ctt tca cta ctg cca tat gga      144
 Glu Glu Leu Ser Thr Glu Gly Ser Val Leu Ser Leu Leu Pro Tyr Gly
          35                  40                  45

 aag agc act gtg gtg tta cta ggt tat cat cct ctc cag aat ctt aaa      192
 Lys Ser Thr Val Val Leu Leu Gly Tyr His Pro Leu Gln Asn Leu Lys
      50                  55                  60

 acc aga gaa gcc agc tgt gtg aat gaa ctt ata aag cct ctt taa          237
 Thr Arg Glu Ala Ser Cys Val Asn Glu Leu Ile Lys Pro Leu 
  65                  70                  75





      <210> 282
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(498)

      <400> 282
  atg aaa att gct gct ttg ttg ggc tgc atg atg atg gca gct cgg tgt      48
  Met Lys Ile Ala Ala Leu Leu Gly Cys Met Met Met Ala Ala Arg Cys
    1               5                  10                  15

 gga act ctc tct gcc atg aga gat ctg agt ttt tca gat gaa aat cgc       96
 Gly Thr Leu Ser Ala Met Arg Asp Leu Ser Phe Ser Asp Glu Asn Arg
              20                  25                  30

 cgg ctg gct gta ggc acg gct gct gct gct gtg agc aca cac aaa ggc      144
 Arg Leu Ala Val Gly Thr Ala Ala Ala Ala Val Ser Thr His Lys Gly
          35                  40                  45

 gtg tgg ctc tgg agc ctg ttt gtc tgt ccc tca agg ctt ccc cct ttc      192
 Val Trp Leu Trp Ser Leu Phe Val Cys Pro Ser Arg Leu Pro Pro Phe
      50                  55                  60

 agc aag gac caa cat cat cct tcc agt ttc cag gcc aag aac cct gga      240
 Ser Lys Asp Gln His His Pro Ser Ser Phe Gln Ala Lys Asn Pro Gly
  65                  70                  75                  80

 gtc atc ctt gac ttt tct ttc ttt cct att cca cat tgg gcc tat gag      288
 Val Ile Leu Asp Phe Ser Phe Phe Pro Ile Pro His Trp Ala Tyr Glu
                  85                  90                  95

 cag atc ctt tca gct ctg ctc caa gcc aaa tgt gga ata gga aag aaa      336
 Gln Ile Leu Ser Ala Leu Leu Gln Ala Lys Cys Gly Ile Gly Lys Lys
             100                 105                 110

 gaa aag ctc caa aat atc cct caa atc cag cta ctt ctc acc aac acc      384
 Glu Lys Leu Gln Asn Ile Pro Gln Ile Gln Leu Leu Leu Thr Asn Thr
         115                 120                 125

 att ctt gtc act ctg gtc cag acc ccc agc att gct ccc ctg gac ttg      432
 Ile Leu Val Thr Leu Val Gln Thr Pro Ser Ile Ala Pro Leu Asp Leu
     130                 135                 140

 cga gtt tgc tgt ctg act tgt ttc tat gct tcc ctg ctt gtg gac aac      480
 Arg Val Cys Cys Leu Thr Cys Phe Tyr Ala Ser Leu Leu Val Asp Asn
 145                 150                 155                 160

 att caa caa atc atc taa                                              498
 Ile Gln Gln Ile Ile 
                 165





      <210> 283
      <211> 897
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(897)

      <400> 283
  atg cct ggc ccc atg tcc ctc tgg ctc ctc ctg ctg gtt ctg cca ctg      48
  Met Pro Gly Pro Met Ser Leu Trp Leu Leu Leu Leu Val Leu Pro Leu
    1               5                  10                  15

 tcc ctg gag cac agt gat ctc aga att tgc ttc ccc ggg cag gtg gtc       96
 Ser Leu Glu His Ser Asp Leu Arg Ile Cys Phe Pro Gly Gln Val Val
              20                  25                  30

 agc atg gaa agc agc tcc acg ggc ttc atc tgg act gat gtc aga gcc      144
 Ser Met Glu Ser Ser Ser Thr Gly Phe Ile Trp Thr Asp Val Arg Ala
          35                  40                  45

 tgg cag aca tca aat cgg cat gtt tct tct tgg agg gaa ccc agg cat      192
 Trp Gln Thr Ser Asn Arg His Val Ser Ser Trp Arg Glu Pro Arg His
      50                  55                  60

 tct cgg atg ccc cct ggg gcc ggc ctc atg gag cgg atc cag gct att      240
 Ser Arg Met Pro Pro Gly Ala Gly Leu Met Glu Arg Ile Gln Ala Ile
  65                  70                  75                  80

 gcc cag aac gtc tcc gac atc gct gtg aag gtg gac cag atc ctg cgc      288
 Ala Gln Asn Val Ser Asp Ile Ala Val Lys Val Asp Gln Ile Leu Arg
                  85                  90                  95

 cac agt ctg ctc ctg cac agc aag gtg tca gaa ggc cgg cgg gac cag      336
 His Ser Leu Leu Leu His Ser Lys Val Ser Glu Gly Arg Arg Asp Gln
             100                 105                 110

 tgt gag gca ccc agt gac ccc aag ttc cct gac tgc tca ggg aag gtg      384
 Cys Glu Ala Pro Ser Asp Pro Lys Phe Pro Asp Cys Ser Gly Lys Val
         115                 120                 125

 gag tgg atg cgt gcc cgc tgg acc tct gac ccc tgc tac gcc ttc ttt      432
 Glu Trp Met Arg Ala Arg Trp Thr Ser Asp Pro Cys Tyr Ala Phe Phe
     130                 135                 140

 ggg gtg gac ggc acc gag tgc tcc ttc ctc atc tac ctc agt gag gtc      480
 Gly Val Asp Gly Thr Glu Cys Ser Phe Leu Ile Tyr Leu Ser Glu Val
 145                 150                 155                 160

 gag tgg ttc tgc ccc ccg ctg ccc tgg agg aac cag acg gct gcc cag      528
 Glu Trp Phe Cys Pro Pro Leu Pro Trp Arg Asn Gln Thr Ala Ala Gln
                 165                 170                 175

 agg gca ccc aag ccc ctc ccc aaa gtc cag gca gtt ttc cga agc aac      576
 Arg Ala Pro Lys Pro Leu Pro Lys Val Gln Ala Val Phe Arg Ser Asn
             180                 185                 190

 ctg tcc cac ctt ctg gac ctg atg ggc agc ggg aag gag tcc ctg atc      624
 Leu Ser His Leu Leu Asp Leu Met Gly Ser Gly Lys Glu Ser Leu Ile
         195                 200                 205

 ttc atg aag aag cgg acc aag agg ctc aca gcc cag tgg gcg ctg gct      672
 Phe Met Lys Lys Arg Thr Lys Arg Leu Thr Ala Gln Trp Ala Leu Ala
     210                 215                 220

 gcc cag cgc ctg gca cag aag ctg ggg gcc acc cag agg gac cag aag      720
 Ala Gln Arg Leu Ala Gln Lys Leu Gly Ala Thr Gln Arg Asp Gln Lys
 225                 230                 235                 240

 cag atc ctg gtc cac atc ggc ttc ctg acg gag gag tcc ggg gac gtg      768
 Gln Ile Leu Val His Ile Gly Phe Leu Thr Glu Glu Ser Gly Asp Val
                 245                 250                 255

 ttc agc cct cgg gtc ctg aag ggc ggg ccc cta ggg gag atg gtg cag      816
 Phe Ser Pro Arg Val Leu Lys Gly Gly Pro Leu Gly Glu Met Val Gln
             260                 265                 270

 tgg gcg gac att ctg act gca ctc tat gtc ctg ggc cat ggc ctg cgg      864
 Trp Ala Asp Ile Leu Thr Ala Leu Tyr Val Leu Gly His Gly Leu Arg
         275                 280                 285

 gtc aca gtc tcc ctg aag gag ctg cag aga tag                          897
 Val Thr Val Ser Leu Lys Glu Leu Gln Arg 
     290                 295





      <210> 284
      <211> 456
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(456)

      <400> 284
  atg act tgc agt gga gtg tta gcc cag ctc cct ata tgg tcg ggg att      48
  Met Thr Cys Ser Gly Val Leu Ala Gln Leu Pro Ile Trp Ser Gly Ile
    1               5                  10                  15

 agc ttg gcg ctg ctg agg ctg agg ctg agc cag gag ctg gag gag gag       96
 Ser Leu Ala Leu Leu Arg Leu Arg Leu Ser Gln Glu Leu Glu Glu Glu
              20                  25                  30

 gtg gag gac gag gac gaa aag gag gag gag aaa gag cgc agc agc agt      144
 Val Glu Asp Glu Asp Glu Lys Glu Glu Glu Lys Glu Arg Ser Ser Ser
          35                  40                  45

 cag cgc acg ccg agc ggc tgc cgg ggg aag cag agg cgc cgg agg ctg      192
 Gln Arg Thr Pro Ser Gly Cys Arg Gly Lys Gln Arg Arg Arg Arg Leu
      50                  55                  60

 ggg cac cgc cga cgc ctc ggg agc cat ggc cga agg ggg aga agg agg      240
 Gly His Arg Arg Arg Leu Gly Ser His Gly Arg Arg Gly Arg Arg Arg
  65                  70                  75                  80

 cga gga cga gat cca gtt tct gag gac tgt gag tct ccg cgg cgg ggg      288
 Arg Gly Arg Asp Pro Val Ser Glu Asp Cys Glu Ser Pro Arg Arg Gly
                  85                  90                  95

 cga ggc cgt ggg cag ggc gcc ccc acg cac agg gga acc tcc ggg aag      336
 Arg Gly Arg Gly Gln Gly Ala Pro Thr His Arg Gly Thr Ser Gly Lys
             100                 105                 110

 gag cca gcg ggg cag ggg gga gtg tgg gga gcc ggg tcg gag aag cgg      384
 Glu Pro Ala Gly Gln Gly Gly Val Trp Gly Ala Gly Ser Glu Lys Arg
         115                 120                 125

 gcg cag gcg ctt ggt cct agc cct ggg atc gct cgg agg gga att cac      432
 Ala Gln Ala Leu Gly Pro Ser Pro Gly Ile Ala Arg Arg Gly Ile His
     130                 135                 140

 cca gcg ctg ccc ctc tcg tgt taa                                      456
 Pro Ala Leu Pro Leu Ser Cys 
 145                 150





      <210> 285
      <211> 372
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(372)

      <400> 285
  atg gtg cac cca atg ctg gtg gat ggc tta gga cgc ttg tat gag caa      48
  Met Val His Pro Met Leu Val Asp Gly Leu Gly Arg Leu Tyr Glu Gln
    1               5                  10                  15

 ata ctg ctc tgg atc ctc ttt cct gct tgg aaa gca gct tca gtc ctg       96
 Ile Leu Leu Trp Ile Leu Phe Pro Ala Trp Lys Ala Ala Ser Val Leu
              20                  25                  30

 aag gtc cag agt gaa tgt gcc ctg acc ctg gct ctg gcc caa gtc tgt      144
 Lys Val Gln Ser Glu Cys Ala Leu Thr Leu Ala Leu Ala Gln Val Cys
          35                  40                  45

 gcc gta gag gca gtt gct gtg gga ggt gtg gta act gct gga agg aag      192
 Ala Val Glu Ala Val Ala Val Gly Gly Val Val Thr Ala Gly Arg Lys
      50                  55                  60

 atg ctc aat tct tct gag caa cga agg cca cac gga gtc ctg gat tct      240
 Met Leu Asn Ser Ser Glu Gln Arg Arg Pro His Gly Val Leu Asp Ser
  65                  70                  75                  80

 gtg tgg cct ggc atc cat ggc gca ctg tgt gct ggc agg tgg ctc agg      288
 Val Trp Pro Gly Ile His Gly Ala Leu Cys Ala Gly Arg Trp Leu Arg
                  85                  90                  95

 acg gta agc att tct ctg ccc agt atg ctg aat gag ggt gtc ttt cgg      336
 Thr Val Ser Ile Ser Leu Pro Ser Met Leu Asn Glu Gly Val Phe Arg
             100                 105                 110

 att tcc aag acc cgc aag gag cag ttt ctc agc taa                      372
 Ile Ser Lys Thr Arg Lys Glu Gln Phe Leu Ser 
         115                 120





      <210> 286
      <211> 426
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(426)

      <400> 286
  atg cta ctg ctg tgg gtg tcg gtg gtc gca gcc ttg gcg ctg gcg gta      48
  Met Leu Leu Leu Trp Val Ser Val Val Ala Ala Leu Ala Leu Ala Val
    1               5                  10                  15

 ctg gcc ccc gga gca ggg gag cag agg cgg aga gca gcc aaa gcg ccc       96
 Leu Ala Pro Gly Ala Gly Glu Gln Arg Arg Arg Ala Ala Lys Ala Pro
              20                  25                  30

 aat gtg gtg ctg gtc gtg agc gac tcc ttc ttt agc tgt tca tct tta      144
 Asn Val Val Leu Val Val Ser Asp Ser Phe Phe Ser Cys Ser Ser Leu
          35                  40                  45

 cca cgc atc gaa agt gct ctt gtc agg gtc acc agc tgt ctc cat act      192
 Pro Arg Ile Glu Ser Ala Leu Val Arg Val Thr Ser Cys Leu His Thr
      50                  55                  60

 gcc aat tcc aat gtg cat ttt ctg gcc tca ttt cag gtc tca tac atc      240
 Ala Asn Ser Asn Val His Phe Leu Ala Ser Phe Gln Val Ser Tyr Ile
  65                  70                  75                  80

 cca gag aag gct tcc ctg tcc aca ctg tct aac gat gga agg tta aca      288
 Pro Glu Lys Ala Ser Leu Ser Thr Leu Ser Asn Asp Gly Arg Leu Thr
                  85                  90                  95

 ttt cat cca gga agt cag gta gtg aaa ctt cct ttt atc aac ttt atg      336
 Phe His Pro Gly Ser Gln Val Val Lys Leu Pro Phe Ile Asn Phe Met
             100                 105                 110

 aag aca cgt ggg act tcc ttt ctg aat gcc tac aca aac tct cca att      384
 Lys Thr Arg Gly Thr Ser Phe Leu Asn Ala Tyr Thr Asn Ser Pro Ile
         115                 120                 125

 tgt tgc cca tca cgc gca gaa tgt aag ctt aat cta aag taa              426
 Cys Cys Pro Ser Arg Ala Glu Cys Lys Leu Asn Leu Lys 
     130                 135                 140





      <210> 287
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 287
  atg ccg gtg tgg tgg cgg cgg cgg aga ctg cgg gcc cgt agc tgg gct      48
  Met Pro Val Trp Trp Arg Arg Arg Arg Leu Arg Ala Arg Ser Trp Ala
    1               5                  10                  15

 ctg cga ggc caa aag gct acg ctc ccg gtg ccc cca agg ccc acg agc       96
 Leu Arg Gly Gln Lys Ala Thr Leu Pro Val Pro Pro Arg Pro Thr Ser
              20                  25                  30

 ttt ccc cac aag cca ttt gcg cag tcg cgt ttt gtg agt aac cac ctg      144
 Phe Pro His Lys Pro Phe Ala Gln Ser Arg Phe Val Ser Asn His Leu
          35                  40                  45

 gaa ggc tta gct gac ctt tct ccg tca aca ccg gtt cgc tgt cct ctg      192
 Glu Gly Leu Ala Asp Leu Ser Pro Ser Thr Pro Val Arg Cys Pro Leu
      50                  55                  60

 ctc aga aac tgg gca agg gcc ttc tga                                  219
 Leu Arg Asn Trp Ala Arg Ala Phe 
  65                  70





      <210> 288
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 288
  atg gct gct ggc tgc ctg ctg gcc ttg act ctg aca ctt ttc caa tct      48
  Met Ala Ala Gly Cys Leu Leu Ala Leu Thr Leu Thr Leu Phe Gln Ser
    1               5                  10                  15

 ttg ctc atc ggc ccc tcg tcg gag gag ccg ttc cct tcg gcc gtc act       96
 Leu Leu Ile Gly Pro Ser Ser Glu Glu Pro Phe Pro Ser Ala Val Thr
              20                  25                  30

 gcc caa act cgt ttt atc cca cgt tac tgg atg cac ttg aca gcc ttc      144
 Ala Gln Thr Arg Phe Ile Pro Arg Tyr Trp Met His Leu Thr Ala Phe
          35                  40                  45

 cga tta gac gcg tgc tgg ctc ccc gcg gcc gag cgt gct gtc cac gca      192
 Arg Leu Asp Ala Cys Trp Leu Pro Ala Ala Glu Arg Ala Val His Ala
      50                  55                  60

 ggg ggc tcg cag gtg tca gtg caa gaa tct gga gga tgc aca ttc tat      240
 Gly Gly Ser Gln Val Ser Val Gln Glu Ser Gly Gly Cys Thr Phe Tyr
  65                  70                  75                  80

 ccc gga gaa ggg gag tgt cta att ttt gtt gtc att gag tta cag taa      288
 Pro Gly Glu Gly Glu Cys Leu Ile Phe Val Val Ile Glu Leu Gln 
                  85                  90                  95





      <210> 289
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 289
  atg ctc ccg ctc cag gtc cgg cgc ccc ggc gcc gcc gcc ggc tta ttg      48
  Met Leu Pro Leu Gln Val Arg Arg Pro Gly Ala Ala Ala Gly Leu Leu
    1               5                  10                  15

 tgg cga ctc gcc tcg cgg cgc tgc cgc tgc act ggg cat tgt tac ttc       96
 Trp Arg Leu Ala Ser Arg Arg Cys Arg Cys Thr Gly His Cys Tyr Phe
              20                  25                  30

 ccc gtc ttt gct tcg gtg ctg ctg gtg tgt ggg gag atg ccc tct cgt      144
 Pro Val Phe Ala Ser Val Leu Leu Val Cys Gly Glu Met Pro Ser Arg
          35                  40                  45

 cgt ccg ctg tcc ccc acg ccc agt cct cgg gga ggc cca gaa ttc cag      192
 Arg Pro Leu Ser Pro Thr Pro Ser Pro Arg Gly Gly Pro Glu Phe Gln
      50                  55                  60

 ccc ctt ctc ccc cag ggg aat att ctt ggg aac cag gtc ttt ccc ggc      240
 Pro Leu Leu Pro Gln Gly Asn Ile Leu Gly Asn Gln Val Phe Pro Gly
  65                  70                  75                  80

 aga atc tag                                                          249
 Arg Ile 






      <210> 290
      <211> 579
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(579)

      <400> 290
  atg ggc ccc gtg tcc ctt ctg atg cag aat cca gtc acc aag ctc caa      48
  Met Gly Pro Val Ser Leu Leu Met Gln Asn Pro Val Thr Lys Leu Gln
    1               5                  10                  15

 ctc tgt ggt cat gcc tgg ctg ttc tgg ggg ctg tgg ggg gct ctg gcc       96
 Leu Cys Gly His Ala Trp Leu Phe Trp Gly Leu Trp Gly Ala Leu Ala
              20                  25                  30

 atc ggc ggg cag cgg ctc ggg ggc ggc cac ctc ctg gat gac cga gcc      144
 Ile Gly Gly Gln Arg Leu Gly Gly Gly His Leu Leu Asp Asp Arg Ala
          35                  40                  45

 agc ccc gtc cac ctc ctc gcc ggc gtc gaa ggc ggg gtt ggc ggc ggc      192
 Ser Pro Val His Leu Leu Ala Gly Val Glu Gly Gly Val Gly Gly Gly
      50                  55                  60

 act cag gtc aac att cac ggc gtc agt tct cag agc cac gat ggt ggc      240
 Thr Gln Val Asn Ile His Gly Val Ser Ser Gln Ser His Asp Gly Gly
  65                  70                  75                  80

 ggc gtc gcc ccg ccg ctc ggc gta gat gcg ttg ctc gaa cac ctg tgc      288
 Gly Val Ala Pro Pro Leu Gly Val Asp Ala Leu Leu Glu His Leu Cys
                  85                  90                  95

 cgc ggc agg cgg gaa ctc ggg gtc gag ggg cac gct ggc ggc ggc gga      336
 Arg Gly Arg Arg Glu Leu Gly Val Glu Gly His Ala Gly Gly Gly Gly
             100                 105                 110

 gcc cat gac ccg ttc agg acc cgg ctg tcc agc ggc ttc cgg ctg ggg      384
 Ala His Asp Pro Phe Arg Thr Arg Leu Ser Ser Gly Phe Arg Leu Gly
         115                 120                 125

 tcg ctg gtg gac gag cgg atg cca gtc ccg cag ctg ttg gcc agc gtg      432
 Ser Leu Val Asp Glu Arg Met Pro Val Pro Gln Leu Leu Ala Ser Val
     130                 135                 140

 ttc ctg gtg gag gga ccg gaa agg cag gca ggc act cct gcc ccg acc      480
 Phe Leu Val Glu Gly Pro Glu Arg Gln Ala Gly Thr Pro Ala Pro Thr
 145                 150                 155                 160

 tac ctg tca aag aag gtg gcc agg agc ctc cgc agc aag acc tta tgc      528
 Tyr Leu Ser Lys Lys Val Ala Arg Ser Leu Arg Ser Lys Thr Leu Cys
                 165                 170                 175

 ttc acc cct gca cac agg tgg cag ttc atc agc tgg ccg cgt gtg atg      576
 Phe Thr Pro Ala His Arg Trp Gln Phe Ile Ser Trp Pro Arg Val Met
             180                 185                 190

 tag                                                                  579
 






      <210> 291
      <211> 456
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(456)

      <400> 291
  atg gtt att tta aac gct ctc cag agg aga gca ttc tta tgt gca gcc      48
  Met Val Ile Leu Asn Ala Leu Gln Arg Arg Ala Phe Leu Cys Ala Ala
    1               5                  10                  15

 aat gtt aag atc ccc aga ttg aga ata aaa gtt aaa aca aaa gaa gct       96
 Asn Val Lys Ile Pro Arg Leu Arg Ile Lys Val Lys Thr Lys Glu Ala
              20                  25                  30

 agt gct cag gta gtc aaa gaa gag tgc aat aag tac ttg ctg ttc ctt      144
 Ser Ala Gln Val Val Lys Glu Glu Cys Asn Lys Tyr Leu Leu Phe Leu
          35                  40                  45

 ctt cct gtt cct tcc gct ggc ctt ctt ccc tca att atg gaa ata gct      192
 Leu Pro Val Pro Ser Ala Gly Leu Leu Pro Ser Ile Met Glu Ile Ala
      50                  55                  60

 gat ccc ttt tca tca ttc ggg tct gag gac aaa tgt tat acc ctc aca      240
 Asp Pro Phe Ser Ser Phe Gly Ser Glu Asp Lys Cys Tyr Thr Leu Thr
  65                  70                  75                  80

 ccg ccc ctc ccg cga cat act gag aaa tcg agt gac tct caa gag aaa      288
 Pro Pro Leu Pro Arg His Thr Glu Lys Ser Ser Asp Ser Gln Glu Lys
                  85                  90                  95

 ggc cat ttt gag gct ggg gtc gaa cca aaa tcc agg ggg tcc aca cca      336
 Gly His Phe Glu Ala Gly Val Glu Pro Lys Ser Arg Gly Ser Thr Pro
             100                 105                 110

 ggt cag tac ccc gga att ggc tgt ttt gca aga ttt cgg gag tac caa      384
 Gly Gln Tyr Pro Gly Ile Gly Cys Phe Ala Arg Phe Arg Glu Tyr Gln
         115                 120                 125

 att ggc atg aga cat ttg aca acg agg cca gcc atg cac cga gct cag      432
 Ile Gly Met Arg His Leu Thr Thr Arg Pro Ala Met His Arg Ala Gln
     130                 135                 140

 gtt tta ttt ccg ttg tcc ttc tga                                      456
 Val Leu Phe Pro Leu Ser Phe 
 145                 150





      <210> 292
      <211> 552
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(552)

      <400> 292
  atg ggc act gtg gga tct ggt gca ttc cgg tcg aca ctc tcg ttt att      48
  Met Gly Thr Val Gly Ser Gly Ala Phe Arg Ser Thr Leu Ser Phe Ile
    1               5                  10                  15

 tgg act tgg cag ttt ttc cct gat gac cca cca ggc ctc cct gaa caa       96
 Trp Thr Trp Gln Phe Phe Pro Asp Asp Pro Pro Gly Leu Pro Glu Gln
              20                  25                  30

 tct ggg aaa tac tca tgg ctg tgg gcg cag agc agg gcg ctg ccc agg      144
 Ser Gly Lys Tyr Ser Trp Leu Trp Ala Gln Ser Arg Ala Leu Pro Arg
          35                  40                  45

 gac agc acc gga tgg gcc agg ccg gat gtg ggg gtc ctc gat gct ggc      192
 Asp Ser Thr Gly Trp Ala Arg Pro Asp Val Gly Val Leu Asp Ala Gly
      50                  55                  60

 cca gcg gcc atc ttg cag cca cag ggg act gag ggc caa gct gcg gga      240
 Pro Ala Ala Ile Leu Gln Pro Gln Gly Thr Glu Gly Gln Ala Ala Gly
  65                  70                  75                  80

 gac tcg gag cta acc gtg ggg gcc ggt cct gcc ggt ttc aca gcc tgc      288
 Asp Ser Glu Leu Thr Val Gly Ala Gly Pro Ala Gly Phe Thr Ala Cys
                  85                  90                  95

 tct ccc ctc tcg gga tgc cga acc ccg tat act cac cat ttc cca gct      336
 Ser Pro Leu Ser Gly Cys Arg Thr Pro Tyr Thr His His Phe Pro Ala
             100                 105                 110

 tcc agg atg tcc tgt cat ctt aac tgt gcg tcc cca agg acc tac aga      384
 Ser Arg Met Ser Cys His Leu Asn Cys Ala Ser Pro Arg Thr Tyr Arg
         115                 120                 125

 tca cag ggc aac agg ggc tgt gaa aga gta gcc cgg ggc tcc caa agc      432
 Ser Gln Gly Asn Arg Gly Cys Glu Arg Val Ala Arg Gly Ser Gln Ser
     130                 135                 140

 gga gga ggc gaa aga gga gac gga tcc caa gtt cct gtg cca gcg cca      480
 Gly Gly Gly Glu Arg Gly Asp Gly Ser Gln Val Pro Val Pro Ala Pro
 145                 150                 155                 160

 gcg aga gac aaa gac ccg cca aac gcc aga agc cac gcc ctc ctc tcc      528
 Ala Arg Asp Lys Asp Pro Pro Asn Ala Arg Ser His Ala Leu Leu Ser
                 165                 170                 175

 tgt cct ctc caa ctg cgc gcc tga                                      552
 Cys Pro Leu Gln Leu Arg Ala 
             180





      <210> 293
      <211> 450
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(450)

      <400> 293
  atg agg gaa aaa caa cac ctg aag gaa gcg gcc act tct cat gca ttt      48
  Met Arg Glu Lys Gln His Leu Lys Glu Ala Ala Thr Ser His Ala Phe
    1               5                  10                  15

 cat gtt cta gtg aca gtg att gtg gta ctt tct aaa ttg ggt ctt tcc       96
 His Val Leu Val Thr Val Ile Val Val Leu Ser Lys Leu Gly Leu Ser
              20                  25                  30

 tgt ttt aga gat gaa aac aat aaa gag aac tac ccc gac gca ggg gct      144
 Cys Phe Arg Asp Glu Asn Asn Lys Glu Asn Tyr Pro Asp Ala Gly Ala
          35                  40                  45

 ctg gta gaa gag cac gcg ccg ccc tct tgg gag ccg cag cag cag aat      192
 Leu Val Glu Glu His Ala Pro Pro Ser Trp Glu Pro Gln Gln Gln Asn
      50                  55                  60

 gta gag gcg acc gtg ctg gtg gac agc gta ttg cga ccc agc atg ggc      240
 Val Glu Ala Thr Val Leu Val Asp Ser Val Leu Arg Pro Ser Met Gly
  65                  70                  75                  80

 aac ttc aag tcc agg aag ccc aag tcc atc ttc aaa gcg gag agc ggg      288
 Asn Phe Lys Ser Arg Lys Pro Lys Ser Ile Phe Lys Ala Glu Ser Gly
                  85                  90                  95

 agg agc cac gga gaa agt cag gta gca gct ctc tct tct cag gct ttt      336
 Arg Ser His Gly Glu Ser Gln Val Ala Ala Leu Ser Ser Gln Ala Phe
             100                 105                 110

 gcc aag acg gtt gag ggg agt aaa gac atg agt gat agt gga att caa      384
 Ala Lys Thr Val Glu Gly Ser Lys Asp Met Ser Asp Ser Gly Ile Gln
         115                 120                 125

 gag ctg cca cct aat tta tca tcc atg tac tgt tgg atg tgg aaa gga      432
 Glu Leu Pro Pro Asn Leu Ser Ser Met Tyr Cys Trp Met Trp Lys Gly
     130                 135                 140

 tgg gag aat gga agc tag                                              450
 Trp Glu Asn Gly Ser 
 145





      <210> 294
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 294
  atg atc ctg acc atg ctg ctg atg ctg aag ctg tgc acc gag gtc cgt      48
  Met Ile Leu Thr Met Leu Leu Met Leu Lys Leu Cys Thr Glu Val Arg
    1               5                  10                  15

 gtg gcc aac gag ctc aac gcc agg cgc cgc tcc ttt aca gaa caa gaa       96
 Val Ala Asn Glu Leu Asn Ala Arg Arg Arg Ser Phe Thr Glu Gln Glu
              20                  25                  30

 gtg ctc atc tgt gcc tgg ccc atc agg tca gac ggt acc agg tca ggc      144
 Val Leu Ile Cys Ala Trp Pro Ile Arg Ser Asp Gly Thr Arg Ser Gly
          35                  40                  45

 gtt tcg tct gtg tgc gtg gcc tgt aca caa aac aca ccc ttt cag ttc      192
 Val Ser Ser Val Cys Val Ala Cys Thr Gln Asn Thr Pro Phe Gln Phe
      50                  55                  60

 tgc tgt gac tca ggg act gag gtg act gtg tgc tgc ttt cag cct ctg      240
 Cys Cys Asp Ser Gly Thr Glu Val Thr Val Cys Cys Phe Gln Pro Leu
  65                  70                  75                  80

 tag                                                                  243
 






      <210> 295
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 295
  atg act atc tgc gtg tcc ctg ggc ttt atg cga tca ctc tgc aac tcg      48
  Met Thr Ile Cys Val Ser Leu Gly Phe Met Arg Ser Leu Cys Asn Ser
    1               5                  10                  15

 gct tct tgt ctg tac aat gtg gag atc aca gcg tcc ctc atg gag tgg       96
 Ala Ser Cys Leu Tyr Asn Val Glu Ile Thr Ala Ser Leu Met Glu Trp
              20                  25                  30

 cca gga gtg tta aag aaa gtg gca cag gag ccc att tgg atc tgg cgc      144
 Pro Gly Val Leu Lys Lys Val Ala Gln Glu Pro Ile Trp Ile Trp Arg
          35                  40                  45

 ata gtt gtg agc tac tat gac cgt cgt tca gac gga ctc acg cag act      192
 Ile Val Val Ser Tyr Tyr Asp Arg Arg Ser Asp Gly Leu Thr Gln Thr
      50                  55                  60

 aga gat gct ctc tta aga cct tgg agc tca tcc gaa agg gaa cac ctc      240
 Arg Asp Ala Leu Leu Arg Pro Trp Ser Ser Ser Glu Arg Glu His Leu
  65                  70                  75                  80

 atg gat ctg ctg aat gtg aag tcc atg ccg aag gaa cca cga cag gag      288
 Met Asp Leu Leu Asn Val Lys Ser Met Pro Lys Glu Pro Arg Gln Glu
                  85                  90                  95

 gag ctg tgt cac caa aca ttc tga                                      312
 Glu Leu Cys His Gln Thr Phe 
             100





      <210> 296
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 296
  atg tac aag gct caa ttc ctt gct gct tct cct ggc cgc tgt ctt ggc      48
  Met Tyr Lys Ala Gln Phe Leu Ala Ala Ser Pro Gly Arg Cys Leu Gly
    1               5                  10                  15

 ctc ctg gct gct tca aat cat cat gca aaa agt att cac ggg ttc aga       96
 Leu Leu Ala Ala Ser Asn His His Ala Lys Ser Ile His Gly Phe Arg
              20                  25                  30

 aga ttg gtg aag aca atg aga aat cga cct gag gag caa aac aaa ggc      144
 Arg Leu Val Lys Thr Met Arg Asn Arg Pro Glu Glu Gln Asn Lys Gly
          35                  40                  45

 atc agc tct tac acc aaa aga gtt aac gct gta acc aaa ggg ttc tgg      192
 Ile Ser Ser Tyr Thr Lys Arg Val Asn Ala Val Thr Lys Gly Phe Trp
      50                  55                  60

 gcc gat cct cag ctt cct cgt ttg gaa aat tct ggc tgc ccc cag ggc      240
 Ala Asp Pro Gln Leu Pro Arg Leu Glu Asn Ser Gly Cys Pro Gln Gly
  65                  70                  75                  80

 ccg ctg aag gtt cca tgg aga gtg gcg gtg aat gca ttt tgg aag cgg      288
 Pro Leu Lys Val Pro Trp Arg Val Ala Val Asn Ala Phe Trp Lys Arg
                  85                  90                  95

 gcc gtg caa gag aag aaa gaa ttg tat gtg cac aag gtt cag gca taa      336
 Ala Val Gln Glu Lys Lys Glu Leu Tyr Val His Lys Val Gln Ala 
             100                 105                 110





      <210> 297
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 297
  atg ggc ttg att gct gtt act gtg acc gct gct act gct gga gtt gca      48
  Met Gly Leu Ile Ala Val Thr Val Thr Ala Ala Thr Ala Gly Val Ala
    1               5                  10                  15

 tta cat aaa tct att caa act gtt cat ttt gtg gat aaa tgg caa aaa       96
 Leu His Lys Ser Ile Gln Thr Val His Phe Val Asp Lys Trp Gln Lys
              20                  25                  30

 ttc tac tcg gat gtg gaa ttc tca gtc aaa gaa gga gag aaa aag caa      144
 Phe Tyr Ser Asp Val Glu Phe Ser Val Lys Glu Gly Glu Lys Lys Gln
          35                  40                  45

 gca acc tgg aaa gca tat ttg agg aca tca tcc atg aaa att tcc cca      192
 Ala Thr Trp Lys Ala Tyr Leu Arg Thr Ser Ser Met Lys Ile Ser Pro
      50                  55                  60

 aac tct aga gag gat aac att cga att caa gaa act cag aga acc cct      240
 Asn Ser Arg Glu Asp Asn Ile Arg Ile Gln Glu Thr Gln Arg Thr Pro
  65                  70                  75                  80

 gtg aga tac tac aca aga caa cta tgt gca aga cat aca gtc atc aga      288
 Val Arg Tyr Tyr Thr Arg Gln Leu Cys Ala Arg His Thr Val Ile Arg
                  85                  90                  95

 ctc tcc aca atc aaa gtg aaa gga aga att atc cat gat gaa cat gcg      336
 Leu Ser Thr Ile Lys Val Lys Gly Arg Ile Ile His Asp Glu His Ala
             100                 105                 110

 tac aaa aat cct caa gag aga agg ggc agt cac cca caa agt aaa ctc      384
 Tyr Lys Asn Pro Gln Glu Arg Arg Gly Ser His Pro Gln Ser Lys Leu
         115                 120                 125

 atc agg cta aca gtg gat ctt tca gca gaa aca cta taa                  423
 Ile Arg Leu Thr Val Asp Leu Ser Ala Glu Thr Leu 
     130                 135                 140





      <210> 298
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 298
  atg tcc ttg gca aac gtg tac ctg ctt tcc ttc att gtt ctc ttc agg      48
  Met Ser Leu Ala Asn Val Tyr Leu Leu Ser Phe Ile Val Leu Phe Arg
    1               5                  10                  15

 ggc ttt ctt cca ctt tcc tct tat gaa acg aat gtg ttt ttg act gtt       96
 Gly Phe Leu Pro Leu Ser Ser Tyr Glu Thr Asn Val Phe Leu Thr Val
              20                  25                  30

 aac tgg gtt cgc ttt cca gat ctg tct ttc cca aat gaa agt ttc ccc      144
 Asn Trp Val Arg Phe Pro Asp Leu Ser Phe Pro Asn Glu Ser Phe Pro
          35                  40                  45

 cag acc cag att ttt tca cac ctc tgc atc ata gac aac tga              186
 Gln Thr Gln Ile Phe Ser His Leu Cys Ile Ile Asp Asn 
      50                  55                  60





      <210> 299
      <211> 618
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(618)

      <400> 299
  atg cct atc cat ctt agt ata atc atg tat tca ttg tgc ttt gtt gta      48
  Met Pro Ile His Leu Ser Ile Ile Met Tyr Ser Leu Cys Phe Val Val
    1               5                  10                  15

 tac att tgc att gac ttc act aat gga tgt gac ctg gtt ggc agc agc       96
 Tyr Ile Cys Ile Asp Phe Thr Asn Gly Cys Asp Leu Val Gly Ser Ser
              20                  25                  30

 agc ttg cac aac atg ctt gtt tgc aaa acc ttt gtt caa caa aac tgc      144
 Ser Leu His Asn Met Leu Val Cys Lys Thr Phe Val Gln Gln Asn Cys
          35                  40                  45

 aga tgc tct gtt gaa tcc act gga gat tgt tct gat act aag gac aag      192
 Arg Cys Ser Val Glu Ser Thr Gly Asp Cys Ser Asp Thr Lys Asp Lys
      50                  55                  60

 tat gct cat atg aca tta aca gac aag aca ctt ttc aga aag aca ggc      240
 Tyr Ala His Met Thr Leu Thr Asp Lys Thr Leu Phe Arg Lys Thr Gly
  65                  70                  75                  80

 aag gag gag ccc cgc aac cat gcc acc acc cct tac tac aag aag cct      288
 Lys Glu Glu Pro Arg Asn His Ala Thr Thr Pro Tyr Tyr Lys Lys Pro
                  85                  90                  95

 ctg tat ggc atc tcc cac aag gtc atg gag aag aag aac cct ccc tcg      336
 Leu Tyr Gly Ile Ser His Lys Val Met Glu Lys Lys Asn Pro Pro Ser
             100                 105                 110

 ggg gac ctg cta aac acc act ggg gca gcc acc aac agt gac cct aac      384
 Gly Asp Leu Leu Asn Thr Thr Gly Ala Ala Thr Asn Ser Asp Pro Asn
         115                 120                 125

 atc tac ttc ctg atc cag gag atg ttc tac atg ctc aac acc ctc acg      432
 Ile Tyr Phe Leu Ile Gln Glu Met Phe Tyr Met Leu Asn Thr Leu Thr
     130                 135                 140

 tcc aac agg tcc cag cta cac agc aaa gtg gac ctg ctc tcc ctg aag      480
 Ser Asn Arg Ser Gln Leu His Ser Lys Val Asp Leu Leu Ser Leu Lys
 145                 150                 155                 160

 gtg gaa gcc gtc tac ccc gtg gag aag gtg gag gag gtg tgg cac tgc      528
 Val Glu Ala Val Tyr Pro Val Glu Lys Val Glu Glu Val Trp His Cys
                 165                 170                 175

 gaa tgt atc ccc agc aac gac gag cag tgc cac tgc cct aac agg aaa      576
 Glu Cys Ile Pro Ser Asn Asp Glu Gln Cys His Cys Pro Asn Arg Lys
             180                 185                 190

 aaa tgc aac atc ctc aag aaa gcc aag aaa gtg gag aag tga              618
 Lys Cys Asn Ile Leu Lys Lys Ala Lys Lys Val Glu Lys 
         195                 200                 205





      <210> 300
      <211> 1065
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1065)

      <400> 300
  atg ctc tcc atg ctt gca gcc ggc ctt ctc tgt gtc cct tgg gtc ccc      48
  Met Leu Ser Met Leu Ala Ala Gly Leu Leu Cys Val Pro Trp Val Pro
    1               5                  10                  15

 cag agc cac acg gcc aca cga aac cag agt ttg ctt gtg atg ggg ctg       96
 Gln Ser His Thr Ala Thr Arg Asn Gln Ser Leu Leu Val Met Gly Leu
              20                  25                  30

 cag aga tct cca aag atg agc tcc agg gct ctc ctg gtg gga gct atc      144
 Gln Arg Ser Pro Lys Met Ser Ser Arg Ala Leu Leu Val Gly Ala Ile
          35                  40                  45

 ggc gac gag gag gag tgg gtc acc ctc tat gaa gag gag aat gag cct      192
 Gly Asp Glu Glu Glu Trp Val Thr Leu Tyr Glu Glu Glu Asn Glu Pro
      50                  55                  60

 gat gcc cag atg ctg gag atc cca aac ctc aca ccc tac act cac tac      240
 Asp Ala Gln Met Leu Glu Ile Pro Asn Leu Thr Pro Tyr Thr His Tyr
  65                  70                  75                  80

 aga ttt cga atg aag caa gtg aac att gtt ggg ccg agc ccc tac agt      288
 Arg Phe Arg Met Lys Gln Val Asn Ile Val Gly Pro Ser Pro Tyr Ser
                  85                  90                  95

 ccg tct tcc cgg gtc atc cag acc ctg cag gcc cca ccc gac gtg gct      336
 Pro Ser Ser Arg Val Ile Gln Thr Leu Gln Ala Pro Pro Asp Val Ala
             100                 105                 110

 cca acc agc gtc acg gtc cgt act gcc agt gag acc agc ctg cgg ctt      384
 Pro Thr Ser Val Thr Val Arg Thr Ala Ser Glu Thr Ser Leu Arg Leu
         115                 120                 125

 cgc tgg gtg ccc ctg ccg gat tct cag tac aac ggg aac ccc gag tcc      432
 Arg Trp Val Pro Leu Pro Asp Ser Gln Tyr Asn Gly Asn Pro Glu Ser
     130                 135                 140

 gtg ggc tac agg att aag tac tgg cgc tca gac ctc cag tcc tca gca      480
 Val Gly Tyr Arg Ile Lys Tyr Trp Arg Ser Asp Leu Gln Ser Ser Ala
 145                 150                 155                 160

 gtg gcc caa gtc gtc agt gac cgg ctg gag aga gaa ttc acc atc gag      528
 Val Ala Gln Val Val Ser Asp Arg Leu Glu Arg Glu Phe Thr Ile Glu
                 165                 170                 175

 gag ctg gag gag tgg atg gaa tac gag ctg cag atg cag gcc ttc aac      576
 Glu Leu Glu Glu Trp Met Glu Tyr Glu Leu Gln Met Gln Ala Phe Asn
             180                 185                 190

 gcc gtc ggg gct ggg ccg tgg agc gag gtg gtg cgg ggc cgg acg cgg      624
 Ala Val Gly Ala Gly Pro Trp Ser Glu Val Val Arg Gly Arg Thr Arg
         195                 200                 205

 gag tca gtt cct tca gcc gcc cct gag aac gtg tca gcc gag gct gtc      672
 Glu Ser Val Pro Ser Ala Ala Pro Glu Asn Val Ser Ala Glu Ala Val
     210                 215                 220

 agc tcg acc cag att tta ctg aca tgg aca tcc gtg ccg gaa cag gac      720
 Ser Ser Thr Gln Ile Leu Leu Thr Trp Thr Ser Val Pro Glu Gln Asp
 225                 230                 235                 240

 cag aat ggg ctc ata ctg ggc tac aag atc ctg ttc cgg gcc aaa gac      768
 Gln Asn Gly Leu Ile Leu Gly Tyr Lys Ile Leu Phe Arg Ala Lys Asp
                 245                 250                 255

 ctg gat ccc gag ccc agg agc cac atc gtg cga ggg aac cac acg cag      816
 Leu Asp Pro Glu Pro Arg Ser His Ile Val Arg Gly Asn His Thr Gln
             260                 265                 270

 tcg gcc ctg ctg gca ggc ctg cgc aag ttc gtg ctc tac gag ctc cag      864
 Ser Ala Leu Leu Ala Gly Leu Arg Lys Phe Val Leu Tyr Glu Leu Gln
         275                 280                 285

 gtg ctg gcg ttc acc cgc atc ggg aac ggg gtc ccc agc acg ccc ctc      912
 Val Leu Ala Phe Thr Arg Ile Gly Asn Gly Val Pro Ser Thr Pro Leu
     290                 295                 300

 atc ctg gag cgc acc aaa gac gat gcc cca ggc cca cca gtg agg ctc      960
 Ile Leu Glu Arg Thr Lys Asp Asp Ala Pro Gly Pro Pro Val Arg Leu
 305                 310                 315                 320

 gtg ttc ccc gaa gtg aga ctc acc tcc gtg cgg ata gtg tgg caa cct     1008
 Val Phe Pro Glu Val Arg Leu Thr Ser Val Arg Ile Val Trp Gln Pro
                 325                 330                 335

 ccg gag gag ccc aac ggc atc atc ctg gaa aaa att cag act att agc     1056
 Pro Glu Glu Pro Asn Gly Ile Ile Leu Glu Lys Ile Gln Thr Ile Ser
             340                 345                 350

 cgg gca tga                                                         1065
 Arg Ala 






      <210> 301
      <211> 825
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(825)

      <400> 301
  atg agg gct ctc aaa ctt cag agg agg aaa tcg ttt tgg att gtc gtg      48
  Met Arg Ala Leu Lys Leu Gln Arg Arg Lys Ser Phe Trp Ile Val Val
    1               5                  10                  15

 gcc tgg gaa gct ttt gtg cag ctg gta aat tat gaa tgt aaa gta gga       96
 Ala Trp Glu Ala Phe Val Gln Leu Val Asn Tyr Glu Cys Lys Val Gly
              20                  25                  30

 gaa tgg aaa ggc cta gct cac tgt gtt tca caa aac aat aaa tac aga      144
 Glu Trp Lys Gly Leu Ala His Cys Val Ser Gln Asn Asn Lys Tyr Arg
          35                  40                  45

 acc aca tac atc ata gca ggg gtc ccc aat ccc cag gaa cca gga tac      192
 Thr Thr Tyr Ile Ile Ala Gly Val Pro Asn Pro Gln Glu Pro Gly Tyr
      50                  55                  60

 aca gca gga ggc cag tta aaa gga aat gat ctg act gtt ctg cat ctg      240
 Thr Ala Gly Gly Gln Leu Lys Gly Asn Asp Leu Thr Val Leu His Leu
  65                  70                  75                  80

 cta gtg att gaa ggc aaa tgg gaa gca gtg cgc aag ttc ccg ttc aag      288
 Leu Val Ile Glu Gly Lys Trp Glu Ala Val Arg Lys Phe Pro Phe Lys
                  85                  90                  95

 aaa tat ata gtg aac acg gct att gtg aag gag gca agg aaa tac tgg      336
 Lys Tyr Ile Val Asn Thr Ala Ile Val Lys Glu Ala Arg Lys Tyr Trp
             100                 105                 110

 gta gaa gag ggc agt tcc ctg gca aag gcc aca cgc tca aac cct gga      384
 Val Glu Glu Gly Ser Ser Leu Ala Lys Ala Thr Arg Ser Asn Pro Gly
         115                 120                 125

 tac ctg cag ccc tac atg aga aca ggc att cct gtt ttt gca ccc cca      432
 Tyr Leu Gln Pro Tyr Met Arg Thr Gly Ile Pro Val Phe Ala Pro Pro
     130                 135                 140

 aag ttg cct ttt ggc cca cca tgc cct cta tcc tgc acg cat ata aac      480
 Lys Leu Pro Phe Gly Pro Pro Cys Pro Leu Ser Cys Thr His Ile Asn
 145                 150                 155                 160

 ccc aaa ccc caa gct cca gaa gca gac cag cag ctc ccc atc cat ctt      528
 Pro Lys Pro Gln Ala Pro Glu Ala Asp Gln Gln Leu Pro Ile His Leu
                 165                 170                 175

 gct gaa agc cat ttc cac cac tca ata aaa cct cgc ata cat cct tca      576
 Ala Glu Ser His Phe His His Ser Ile Lys Pro Arg Ile His Pro Ser
             180                 185                 190

 agt ccg tgt gtg acc cga ttt ttc ctg gat gct gaa aga gag ctc ggg      624
 Ser Pro Cys Val Thr Arg Phe Phe Leu Asp Ala Glu Arg Glu Leu Gly
         195                 200                 205

 ata cag aaa gct gtc ccc tgg tcc ttt acc ctt gtg aaa aag cag aag      672
 Ile Gln Lys Ala Val Pro Trp Ser Phe Thr Leu Val Lys Lys Gln Lys
     210                 215                 220

 tca ctg gga ctt cca tca gtg caa gat ttc ggc agt gtc tac aaa atg      720
 Ser Leu Gly Leu Pro Ser Val Gln Asp Phe Gly Ser Val Tyr Lys Met
 225                 230                 235                 240

 aac att tgg tct gat gta gcg tgc tgt gac cca cag ctg caa caa cca      768
 Asn Ile Trp Ser Asp Val Ala Cys Cys Asp Pro Gln Leu Gln Gln Pro
                 245                 250                 255

 gct gcg tct gct caa act tca gcc atc agc cag ctc agt cgt gta acg      816
 Ala Ala Ser Ala Gln Thr Ser Ala Ile Ser Gln Leu Ser Arg Val Thr
             260                 265                 270

 gaa tct tag                                                          825
 Glu Ser 






      <210> 302
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 302
  atg tca cac aat act gtc tta tgt gtt tta cat tta cag tgc tat gcc      48
  Met Ser His Asn Thr Val Leu Cys Val Leu His Leu Gln Cys Tyr Ala
    1               5                  10                  15

 ata cct ttc tct tgt gta cat tcg gaa aca gaa gcc atc tgt gac cct       96
 Ile Pro Phe Ser Cys Val His Ser Glu Thr Glu Ala Ile Cys Asp Pro
              20                  25                  30

 tcc agc tct tgc ctg gcg ctg caa agc act ggc tcc act gac tta act      144
 Ser Ser Ser Cys Leu Ala Leu Gln Ser Thr Gly Ser Thr Asp Leu Thr
          35                  40                  45

 atc aat tac aaa tac aac atc agg aat agt gat acc cgt ctc tgc aat      192
 Ile Asn Tyr Lys Tyr Asn Ile Arg Asn Ser Asp Thr Arg Leu Cys Asn
      50                  55                  60

 att ggt tgc taa                                                      204
 Ile Gly Cys 
  65





      <210> 303
      <211> 561
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(561)

      <400> 303
  atg gct ggg tgg atg acg atc tta gaa ggg gtt cca ggg cta gct ggc      48
  Met Ala Gly Trp Met Thr Ile Leu Glu Gly Val Pro Gly Leu Ala Gly
    1               5                  10                  15

 ttt ctg ttt ctc cca ctc aag cac cca agc cct gac cca caa agt aaa       96
 Phe Leu Phe Leu Pro Leu Lys His Pro Ser Pro Asp Pro Gln Ser Lys
              20                  25                  30

 gga aca ggc gaa act tct cgc caa ata gct tca agg cag aaa cta cgc      144
 Gly Thr Gly Glu Thr Ser Arg Gln Ile Ala Ser Arg Gln Lys Leu Arg
          35                  40                  45

 agc tgg ctt ggg aat tcc gta caa cgc gaa cgc gca tgc aca ggc agg      192
 Ser Trp Leu Gly Asn Ser Val Gln Arg Glu Arg Ala Cys Thr Gly Arg
      50                  55                  60

 act gag cgt gtc cat ctt cgc att act ccc gga gat gac tct cgg aaa      240
 Thr Glu Arg Val His Leu Arg Ile Thr Pro Gly Asp Asp Ser Arg Lys
  65                  70                  75                  80

 cgt tca tct gca tct cat tac cgg gta gca gga ata agt agg ctg acc      288
 Arg Ser Ser Ala Ser His Tyr Arg Val Ala Gly Ile Ser Arg Leu Thr
                  85                  90                  95

 ctc agt ttg gac cgg gaa cag ctg tat ctg gag cag tcc act gag gga      336
 Leu Ser Leu Asp Arg Glu Gln Leu Tyr Leu Glu Gln Ser Thr Glu Gly
             100                 105                 110

 cct gaa caa gat aaa cgg gaa ggg aaa agc gcc aga agt tcg agc aga      384
 Pro Glu Gln Asp Lys Arg Glu Gly Lys Ser Ala Arg Ser Ser Ser Arg
         115                 120                 125

 gaa ccc acc ggg cag ccg cgg acg tta ctg gga gga atg agg gcg agg      432
 Glu Pro Thr Gly Gln Pro Arg Thr Leu Leu Gly Gly Met Arg Ala Arg
     130                 135                 140

 aag aga aag acg tta gtc ctc gga ccg ttt ccg aga gtc atc tcc ggg      480
 Lys Arg Lys Thr Leu Val Leu Gly Pro Phe Pro Arg Val Ile Ser Gly
 145                 150                 155                 160

 agt aat gcg aag atg gac acg ctc agt cct gcc tgt gca tgc gcg ttc      528
 Ser Asn Ala Lys Met Asp Thr Leu Ser Pro Ala Cys Ala Cys Ala Phe
                 165                 170                 175

 gcg ttg tac gga att ccc aag cca gct gcg tag                          561
 Ala Leu Tyr Gly Ile Pro Lys Pro Ala Ala 
             180                 185





      <210> 304
      <211> 840
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(840)

      <400> 304
  atg gct gag att ttg ctg ttt tgt tcc ctg ctg tgt tca cag ggc cta      48
  Met Ala Glu Ile Leu Leu Phe Cys Ser Leu Leu Cys Ser Gln Gly Leu
    1               5                  10                  15

 gaa cag ggt ttt tat cgg tgg tca gat gaa cac acg act cca tct cca       96
 Glu Gln Gly Phe Tyr Arg Trp Ser Asp Glu His Thr Thr Pro Ser Pro
              20                  25                  30

 gcg gag ccg ggg aaa cga ggc gag ctg cct ggg cag ttt ggg gcc acc      144
 Ala Glu Pro Gly Lys Arg Gly Glu Leu Pro Gly Gln Phe Gly Ala Thr
          35                  40                  45

 ttc tgt ctg cca gac ctg gtg cga tat gat gga cac tca gct tcc aac      192
 Phe Cys Leu Pro Asp Leu Val Arg Tyr Asp Gly His Ser Ala Ser Asn
      50                  55                  60

 att cgg gaa agg cgt gcc cgg atc gcg agg ggc cgc tgg gac cga gtc      240
 Ile Arg Glu Arg Arg Ala Arg Ile Ala Arg Gly Arg Trp Asp Arg Val
  65                  70                  75                  80

 ccg gac gtc gcg acg cgc agg ggg ctg ctg ctg ccg gcg gtc tcg gga      288
 Pro Asp Val Ala Thr Arg Arg Gly Leu Leu Leu Pro Ala Val Ser Gly
                  85                  90                  95

 aaa gtg agg gga cgg agg cgc cca agc aac gtg ggt ttc ggg aac tgt      336
 Lys Val Arg Gly Arg Arg Arg Pro Ser Asn Val Gly Phe Gly Asn Cys
             100                 105                 110

 gag tat ttc act ttg cgt aga gcc ccc tcg ggc aat gcg acc cag aac      384
 Glu Tyr Phe Thr Leu Arg Arg Ala Pro Ser Gly Asn Ala Thr Gln Asn
         115                 120                 125

 cga ggg ctt ctt tcc ccc gcc ggg gcc tcc ctc ccg ttc tcc act cgg      432
 Arg Gly Leu Leu Ser Pro Ala Gly Ala Ser Leu Pro Phe Ser Thr Arg
     130                 135                 140

 aac aaa cag cct gca gtt ccc gca gct gca ggc cgg gcc gcg gaa cat      480
 Asn Lys Gln Pro Ala Val Pro Ala Ala Ala Gly Arg Ala Ala Glu His
 145                 150                 155                 160

 gcg ccg gga gcg ggg ccc ggg cgg gac tcc gga gct ggt act gct ccc      528
 Ala Pro Gly Ala Gly Pro Gly Arg Asp Ser Gly Ala Gly Thr Ala Pro
                 165                 170                 175

 ccc gct tcg gcg cgc ggc atc gtg cgg cct cct tcc tcc ctg tcc tgc      576
 Pro Ala Ser Ala Arg Gly Ile Val Arg Pro Pro Ser Ser Leu Ser Cys
             180                 185                 190

 cgc gct cgc cgg agg cgg cgg cgg agg ggc gag acg cgg ccc ttc ggc      624
 Arg Ala Arg Arg Arg Arg Arg Arg Arg Gly Glu Thr Arg Pro Phe Gly
         195                 200                 205

 ggc acc tcc tcc ccg ggc agg cgc ggc gga gcc ggg cgc ctc agc cag      672
 Gly Thr Ser Ser Pro Gly Arg Arg Gly Gly Ala Gly Arg Leu Ser Gln
     210                 215                 220

 cgc ggc ggg agc agc gca gcg cgg ccc gcg ggc agc gca gcc gca ttc      720
 Arg Gly Gly Ser Ser Ala Ala Arg Pro Ala Gly Ser Ala Ala Ala Phe
 225                 230                 235                 240

 gaa cct ccc tcg caa aga cag tct ccg ccc cac aat gca ccg cgg cgg      768
 Glu Pro Pro Ser Gln Arg Gln Ser Pro Pro His Asn Ala Pro Arg Arg
                 245                 250                 255

 gca gcc ttt gaa aaa gcg gcg cgg ctc gtt caa gat ggg gag ctc gac      816
 Ala Ala Phe Glu Lys Ala Ala Arg Leu Val Gln Asp Gly Glu Leu Asp
             260                 265                 270

 cag ttg cct gac gag agt gag tag                                      840
 Gln Leu Pro Asp Glu Ser Glu 
         275





      <210> 305
      <211> 600
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(600)

      <400> 305
  atg aca gct ttc tgg ttc ctc ctc tat ggt tct tgc caa att gtt gcc      48
  Met Thr Ala Phe Trp Phe Leu Leu Tyr Gly Ser Cys Gln Ile Val Ala
    1               5                  10                  15

 tac aat gca aca cat gcg gta gaa cat gaa gaa ctt cct ggt tgt cgg       96
 Tyr Asn Ala Thr His Ala Val Glu His Glu Glu Leu Pro Gly Cys Arg
              20                  25                  30

 gaa ggg gag cca ggt cag aga cca cca agg tct gta act tgt ttg ctg      144
 Glu Gly Glu Pro Gly Gln Arg Pro Pro Arg Ser Val Thr Cys Leu Leu
          35                  40                  45

 gaa aag atc tcc tct gag gtt caa gca gtt tta tcc ttg tgc cct cat      192
 Glu Lys Ile Ser Ser Glu Val Gln Ala Val Leu Ser Leu Cys Pro His
      50                  55                  60

 ccc caa att tat ccc ctg agg agg cag ttt gat gcc atg gag act act      240
 Pro Gln Ile Tyr Pro Leu Arg Arg Gln Phe Asp Ala Met Glu Thr Thr
  65                  70                  75                  80

 gga cct ctg ctg gtt gac ttc gag ccc atc gca ctc cag gtt cta cac      288
 Gly Pro Leu Leu Val Asp Phe Glu Pro Ile Ala Leu Gln Val Leu His
                  85                  90                  95

 caa gat acc gcc aat gtt aag gcc tct ctt cag gcc tta gag gag aaa      336
 Gln Asp Thr Ala Asn Val Lys Ala Ser Leu Gln Ala Leu Glu Glu Lys
             100                 105                 110

 gca aga aga cct agc ctg gag ccc aag cgt ctg cca cct ccc act gtt      384
 Ala Arg Arg Pro Ser Leu Glu Pro Lys Arg Leu Pro Pro Pro Thr Val
         115                 120                 125

 cag act ttt ccc cac agc gaa tct ttc cag gaa gga cgc tgt aat ggc      432
 Gln Thr Phe Pro His Ser Glu Ser Phe Gln Glu Gly Arg Cys Asn Gly
     130                 135                 140

 gtt cta cac caa gat atc gcc aat gta cag gtt tct ctt cag gag ttc      480
 Val Leu His Gln Asp Ile Ala Asn Val Gln Val Ser Leu Gln Glu Phe
 145                 150                 155                 160

 cag gag aag cca aga aga cct agc ctg gag ccc aaa cct ctt cca cca      528
 Gln Glu Lys Pro Arg Arg Pro Ser Leu Glu Pro Lys Pro Leu Pro Pro
                 165                 170                 175

 ccg cac aga tca gac ctt ccc cca cag cca ggc ttc ccg gaa aga agc      576
 Pro His Arg Ser Asp Leu Pro Pro Gln Pro Gly Phe Pro Glu Arg Ser
             180                 185                 190

 tat aat ggc gta ttg cgt tat taa                                      600
 Tyr Asn Gly Val Leu Arg Tyr 
         195





      <210> 306
      <211> 1194
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1194)

      <400> 306
  atg gtt agc gtg ctc tcc gtg gtt agc gtg ctc tcc gtg gtt agc gtg      48
  Met Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val
    1               5                  10                  15

 ctc tcc gtg gtt agc gtg ctc tcc gtg gtt aac gtg ccc tcc gtg gtt       96
 Leu Ser Val Val Ser Val Leu Ser Val Val Asn Val Pro Ser Val Val
              20                  25                  30

 agc gtg ccc tcc ctg gtt agt gtg ccc tcc ctg gtt agc atg ctc tcc      144
 Ser Val Pro Ser Leu Val Ser Val Pro Ser Leu Val Ser Met Leu Ser
          35                  40                  45

 gtg ttt agc gtg ctc tcc gtg tgt gct ctc tcc atg gtt agc gtg ctc      192
 Val Phe Ser Val Leu Ser Val Cys Ala Leu Ser Met Val Ser Val Leu
      50                  55                  60

 gcc gtg gtt agc gtg ctc tcc gtg gtt agc gtg ctc tct gtg gtt aac      240
 Ala Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val Val Asn
  65                  70                  75                  80

 gtg ctc tcc gtg gtt agc gtg ctc tcc gtg gtt agc gtg ttc tcc gtg      288
 Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val Phe Ser Val
                  85                  90                  95

 gtt agt gtg ttc tcc gtg gtt agc gtg ctc tcc atg gtt agc gtg ctc      336
 Val Ser Val Phe Ser Val Val Ser Val Leu Ser Met Val Ser Val Leu
             100                 105                 110

 tcc atg gat agt gtg ctc tcc gtg gtt agc gtg ctc tcc gtg ggt agc      384
 Ser Met Asp Ser Val Leu Ser Val Val Ser Val Leu Ser Val Gly Ser
         115                 120                 125

 gtg ctc tct ctg gtt agc gtg ctc tcc gtg gtt agc gtg ctc tcc gtg      432
 Val Leu Ser Leu Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val
     130                 135                 140

 gtt agc gtg ctc tct ctg gtt agc gtg ctc tcc gtg gtt agc gtg ctc      480
 Val Ser Val Leu Ser Leu Val Ser Val Leu Ser Val Val Ser Val Leu
 145                 150                 155                 160

 tcc gtg gtt agc gtg ctc tcc gtg gtt agc gtg ctc tct ctg gtt agc      528
 Ser Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Leu Val Ser
                 165                 170                 175

 gtg ctc tcc gtg gtt agc gtg ctc tct gtg gtt agc gtg ctc tct gtg      576
 Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val
             180                 185                 190

 gtt agc gtg ctc tcc gtg gat agc gtg ctc tct gtg gtt agc gtg ctc      624
 Val Ser Val Leu Ser Val Asp Ser Val Leu Ser Val Val Ser Val Leu
         195                 200                 205

 tcc gtg gtt agt gtg ctc tct gtg gtt agt gtg ttc tcc gtg gtt agc      672
 Ser Val Val Ser Val Leu Ser Val Val Ser Val Phe Ser Val Val Ser
     210                 215                 220

 atg ttc ccc atg gtc gct ctg gtg cag tgg aca gag agt gtg ggc ctc      720
 Met Phe Pro Met Val Ala Leu Val Gln Trp Thr Glu Ser Val Gly Leu
 225                 230                 235                 240

 acg ctg gtc agc agg gac ctc acc tcc atg cag ctg aag acc ccc agt      768
 Thr Leu Val Ser Arg Asp Leu Thr Ser Met Gln Leu Lys Thr Pro Ser
                 245                 250                 255

 ggc cag gtc ctc agc ttc tgc att ctg cag ctg ttt ccc ttc acc tcc      816
 Gly Gln Val Leu Ser Phe Cys Ile Leu Gln Leu Phe Pro Phe Thr Ser
             260                 265                 270

 gag agc aag cgg atg ggc gtc atc gtc agg gat gaa tcc acg gca gaa      864
 Glu Ser Lys Arg Met Gly Val Ile Val Arg Asp Glu Ser Thr Ala Glu
         275                 280                 285

 atc aca ttc tac atg aag ggc gct gac gtg gcc atg tct cct atc gtg      912
 Ile Thr Phe Tyr Met Lys Gly Ala Asp Val Ala Met Ser Pro Ile Val
     290                 295                 300

 cag tat aat gac tgg ctg gaa gag gag tgc gga aac atg gct cgc gaa      960
 Gln Tyr Asn Asp Trp Leu Glu Glu Glu Cys Gly Asn Met Ala Arg Glu
 305                 310                 315                 320

 gga ctg cgg acc ctc gtg gtt gca aag aag gcg ttg aca gag gag cag     1008
 Gly Leu Arg Thr Leu Val Val Ala Lys Lys Ala Leu Thr Glu Glu Gln
                 325                 330                 335

 tac cag gac ttt gag agc cga tac act caa gcc aag ctg agc atg cac     1056
 Tyr Gln Asp Phe Glu Ser Arg Tyr Thr Gln Ala Lys Leu Ser Met His
             340                 345                 350

 gac agg tcc ctc aag gtg gcc gcg gta gtc gag agc ctg gag agg gag     1104
 Asp Arg Ser Leu Lys Val Ala Ala Val Val Glu Ser Leu Glu Arg Glu
         355                 360                 365

 atg gaa ctg ctg tgc ctc acc ggc gtg gag gac cag ctg cag gca gac     1152
 Met Glu Leu Leu Cys Leu Thr Gly Val Glu Asp Gln Leu Gln Ala Asp
     370                 375                 380

 gtg cgg ccc acg ctg gag atg ctg cgc aac gcc ggg atc aag             1194
 Val Arg Pro Thr Leu Glu Met Leu Arg Asn Ala Gly Ile Lys 
 385                 390                 395





      <210> 307
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 307
  atg gcc tgg tcc acc tgc cag ctg ctg tgg aga ctg tgt atg tca tgt      48
  Met Ala Trp Ser Thr Cys Gln Leu Leu Trp Arg Leu Cys Met Ser Cys
    1               5                  10                  15

 tat gga aat cag gct ctg agt aag aaa ctg gag caa tcc cac tgg cat       96
 Tyr Gly Asn Gln Ala Leu Ser Lys Lys Leu Glu Gln Ser His Trp His
              20                  25                  30

 tct aat tgc tgt att ctt aac act ggt cca gat gtc tta gaa gca ctt      144
 Ser Asn Cys Cys Ile Leu Asn Thr Gly Pro Asp Val Leu Glu Ala Leu
          35                  40                  45

 gag tct ttg agt ccc tca ggt gtt gat agt ggc tcc atg gtt tca gga      192
 Glu Ser Leu Ser Pro Ser Gly Val Asp Ser Gly Ser Met Val Ser Gly
      50                  55                  60

 ggt gta ggt caa gtg aag agg tct tcc ctc tat gtg agt aca tct tct      240
 Gly Val Gly Gln Val Lys Arg Ser Ser Leu Tyr Val Ser Thr Ser Ser
  65                  70                  75                  80

 ggt aat gct gaa ggt ggt att tgt gag aaa gct cag ccc agc aat aat      288
 Gly Asn Ala Glu Gly Gly Ile Cys Glu Lys Ala Gln Pro Ser Asn Asn
                  85                  90                  95

 ggt agt agc aaa act gac aat aag gtt ccc ttt gga tac aca cag aga      336
 Gly Ser Ser Lys Thr Asp Asn Lys Val Pro Phe Gly Tyr Thr Gln Arg
             100                 105                 110

 gag aag cag ttg aaa aca aaa acc agt gtt gga gag aag caa aga tga      384
 Glu Lys Gln Leu Lys Thr Lys Thr Ser Val Gly Glu Lys Gln Arg 
         115                 120                 125





      <210> 308
      <211> 624
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(624)

      <400> 308
  atg ccg gct ctg gaa acg gtg gct ggg gtg gcc gtc ctc agg tgg ctg      48
  Met Pro Ala Leu Glu Thr Val Ala Gly Val Ala Val Leu Arg Trp Leu
    1               5                  10                  15

 att tcg aac acc agc ctc atg gtg cgg ttc agg ggg atc cgc tcg ttg       96
 Ile Ser Asn Thr Ser Leu Met Val Arg Phe Arg Gly Ile Arg Ser Leu
              20                  25                  30

 ctg gcc agg ccc ggg tgc tac gtg ccc act gct ccc cat aaa ctt tgt      144
 Leu Ala Arg Pro Gly Cys Tyr Val Pro Thr Ala Pro His Lys Leu Cys
          35                  40                  45

 tac cat ggt gcc acc att gca ggc cac gtg cct gtg tgc ccc acc cta      192
 Tyr His Gly Ala Thr Ile Ala Gly His Val Pro Val Cys Pro Thr Leu
      50                  55                  60

 gcc tgg gga ggc tgg cct tcc acg tgg gaa cgg ctg agc aca cgc tca      240
 Ala Trp Gly Gly Trp Pro Ser Thr Trp Glu Arg Leu Ser Thr Arg Ser
  65                  70                  75                  80

 ctg cac tgg acc agg agt gcc cct gca gcc tgt ccc ggg acc acc ctc      288
 Leu His Trp Thr Arg Ser Ala Pro Ala Ala Cys Pro Gly Thr Thr Leu
                  85                  90                  95

 gtt acc atc ttt cca ttc cct ggt cac tgg gtt gat gat gcc aaa gag      336
 Val Thr Ile Phe Pro Phe Pro Gly His Trp Val Asp Asp Ala Lys Glu
             100                 105                 110

 ctc gtc gca ggt gac ggc ctt ggg gtc cag gtc cac ggc gac cgg ctt      384
 Leu Val Ala Gly Asp Gly Leu Gly Val Gln Val His Gly Asp Arg Leu
         115                 120                 125

 cct ctt cag gtt ctg ata ggt ctt gtt gag gga ttt gag gac ctg gcg      432
 Pro Leu Gln Val Leu Ile Gly Leu Val Glu Gly Phe Glu Asp Leu Ala
     130                 135                 140

 aag atc cct gca agg tcc ctg gag cgg gtg aca cac ctg aga ttt gcc      480
 Lys Ile Pro Ala Arg Ser Leu Glu Arg Val Thr His Leu Arg Phe Ala
 145                 150                 155                 160

 gct gcc cgc att ccc gac gat gaa cac gga gtg gcg gac ctg cag cag      528
 Ala Ala Arg Ile Pro Asp Asp Glu His Gly Val Ala Asp Leu Gln Gln
                 165                 170                 175

 ctc ctc cag ctg cac cac ctt cag cac gaa gct gtc ctc cgc ctg cag      576
 Leu Leu Gln Leu His His Leu Gln His Glu Ala Val Leu Arg Leu Gln
             180                 185                 190

 ctt gag ctc cac gat gct ctg ctt gat gat ctg ggg aga cat gga tga      624
 Leu Glu Leu His Asp Ala Leu Leu Asp Asp Leu Gly Arg His Gly 
         195                 200                 205





      <210> 309
      <211> 246
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(246)

      <400> 309
  atg cgt aga ttt agg gag ctg atg agt ttg gtc cta gtt ctt acc cat      48
  Met Arg Arg Phe Arg Glu Leu Met Ser Leu Val Leu Val Leu Thr His
    1               5                  10                  15

 gat gct tca aac aaa gac aac agg gct ata tcc gtc gca ccg gaa gaa       96
 Asp Ala Ser Asn Lys Asp Asn Arg Ala Ile Ser Val Ala Pro Glu Glu
              20                  25                  30

 caa gtt cct gct tca tca cag aac agg cac tct ata ttt gct gca gcg      144
 Gln Val Pro Ala Ser Ser Gln Asn Arg His Ser Ile Phe Ala Ala Ala
          35                  40                  45

 agt gaa ctc tgg gca agg gta cag aaa aga ggt gca cag agg cct gtt      192
 Ser Glu Leu Trp Ala Arg Val Gln Lys Arg Gly Ala Gln Arg Pro Val
      50                  55                  60

 tct agt aac aca ggc tgg cct cct gtt gaa gac atg agg atg aca gac      240
 Ser Ser Asn Thr Gly Trp Pro Pro Val Glu Asp Met Arg Met Thr Asp
  65                  70                  75                  80

 gca taa                                                              246
 Ala 






      <210> 310
      <211> 255
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(255)

      <400> 310
  atg ctc ttc cca gct gcc ttc att gga ttg ttt gtc ttt ttg tat ggc      48
  Met Leu Phe Pro Ala Ala Phe Ile Gly Leu Phe Val Phe Leu Tyr Gly
    1               5                  10                  15

 gtc acc act ctg gat cac agc caa gtc agt aaa gaa gtc tgc caa gct       96
 Val Thr Thr Leu Asp His Ser Gln Val Ser Lys Glu Val Cys Gln Ala
              20                  25                  30

 aca gat atc atc atg tgt cct gtg tgt gat aaa tac tgt cca ttc atg      144
 Thr Asp Ile Ile Met Cys Pro Val Cys Asp Lys Tyr Cys Pro Phe Met
          35                  40                  45

 agg ctg tca gac agc tgt gta tat gcc aag gta att tca aac tgt agc      192
 Arg Leu Ser Asp Ser Cys Val Tyr Ala Lys Val Ile Ser Asn Cys Ser
      50                  55                  60

 att tta gat gaa ttg aat tta aca tac acc ttc ctg agg gat gaa aga      240
 Ile Leu Asp Glu Leu Asn Leu Thr Tyr Thr Phe Leu Arg Asp Glu Arg
  65                  70                  75                  80

 agc tca gtc ttc tga                                                  255
 Ser Ser Val Phe 






      <210> 311
      <211> 855
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(855)

      <400> 311
  atg ggc cag gtc cat gta ctt ctg tgg ctg agg aag gcc ttc att cta      48
  Met Gly Gln Val His Val Leu Leu Trp Leu Arg Lys Ala Phe Ile Leu
    1               5                  10                  15

 agt cca gtc cat tac ccc ttt aag gtg cag aac agt aag atg cct gag       96
 Ser Pro Val His Tyr Pro Phe Lys Val Gln Asn Ser Lys Met Pro Glu
              20                  25                  30

 atg gtg aga aga ggg cta ggt caa tac cca gag cac cac cac cag gag      144
 Met Val Arg Arg Gly Leu Gly Gln Tyr Pro Glu His His His Gln Glu
          35                  40                  45

 gcc tgg aag caa ctc act gtc cca ctt gat gtg gcc tgt gga cca cca      192
 Ala Trp Lys Gln Leu Thr Val Pro Leu Asp Val Ala Cys Gly Pro Pro
      50                  55                  60

 gaa att tca gag cgt cac aga gat gtg tgg ttc gat cct gag cag ttc      240
 Glu Ile Ser Glu Arg His Arg Asp Val Trp Phe Asp Pro Glu Gln Phe
  65                  70                  75                  80

 tgt gac tac ctg gtt gca gga cct gga gca aga cac ttt ccc cct cca      288
 Cys Asp Tyr Leu Val Ala Gly Pro Gly Ala Arg His Phe Pro Pro Pro
                  85                  90                  95

 agc ctg gtg ttc cgg ctg caa aat gaa aac agc tgt act tac ttc aca      336
 Ser Leu Val Phe Arg Leu Gln Asn Glu Asn Ser Cys Thr Tyr Phe Thr
             100                 105                 110

 ggc cta gca gca gag ttc aat ggt cca tgg agg caa ggc aga cac cag      384
 Gly Leu Ala Ala Glu Phe Asn Gly Pro Trp Arg Gln Gly Arg His Gln
         115                 120                 125

 gaa tac cag gag cag ctg ctg cct gag aga gtg ggg ggc ctc cag agc      432
 Glu Tyr Gln Glu Gln Leu Leu Pro Glu Arg Val Gly Gly Leu Gln Ser
     130                 135                 140

 ccc cag aag agt ctt cct aac ctc ttt cca tca ggt ttt aac atc aca      480
 Pro Gln Lys Ser Leu Pro Asn Leu Phe Pro Ser Gly Phe Asn Ile Thr
 145                 150                 155                 160

 ctg aga tgg gga ggt ggc agg aga cag gtg atg ttt acc ctg ctg agg      528
 Leu Arg Trp Gly Gly Gly Arg Arg Gln Val Met Phe Thr Leu Leu Arg
                 165                 170                 175

 cca gag ttg cca aaa ggc ttc aat caa tcc ttt gaa tct gca cct ggc      576
 Pro Glu Leu Pro Lys Gly Phe Asn Gln Ser Phe Glu Ser Ala Pro Gly
             180                 185                 190

 cct gag tcc caa aat aac aac cag ggc agc tta cct gat ctg cag ggc      624
 Pro Glu Ser Gln Asn Asn Asn Gln Gly Ser Leu Pro Asp Leu Gln Gly
         195                 200                 205

 tgg gac agg aag cag tcc atg gaa gtc atc gca atg gca ttt cct gaa      672
 Trp Asp Arg Lys Gln Ser Met Glu Val Ile Ala Met Ala Phe Pro Glu
     210                 215                 220

 gag ctg gag aaa aac ctc cag ttc cga ggg gag cac tgg agg ctg ccc      720
 Glu Leu Glu Lys Asn Leu Gln Phe Arg Gly Glu His Trp Arg Leu Pro
 225                 230                 235                 240

 aaa aag ctg tgt ggc tca gag ttc act gct aaa caa aaa gac cca gtg      768
 Lys Lys Leu Cys Gly Ser Glu Phe Thr Ala Lys Gln Lys Asp Pro Val
                 245                 250                 255

 gga ttg cct gac tca ggt ctg cca act ggg aac aag gaa gac aga ctg      816
 Gly Leu Pro Asp Ser Gly Leu Pro Thr Gly Asn Lys Glu Asp Arg Leu
             260                 265                 270

 tcg gat aga ggg gca gaa gag aag agg atc cag gag tag                  855
 Ser Asp Arg Gly Ala Glu Glu Lys Arg Ile Gln Glu 
         275                 280





      <210> 312
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 312
  atg gca gca ata ctg gta cct tca gca ttg gcc aca gtg ctg gaa gtc      48
  Met Ala Ala Ile Leu Val Pro Ser Ala Leu Ala Thr Val Leu Glu Val
    1               5                  10                  15

 ctg gcc aga gca atc aga caa gag aaa gaa ata aat ggc atc caa atc       96
 Leu Ala Arg Ala Ile Arg Gln Glu Lys Glu Ile Asn Gly Ile Gln Ile
              20                  25                  30

 agt gaa gag gaa gtc aaa ctg ttg ccg ttt gtt ggt gat atg att gtt      144
 Ser Glu Glu Glu Val Lys Leu Leu Pro Phe Val Gly Asp Met Ile Val
          35                  40                  45

 tac tta gaa aac cct aaa gac tcc tcc aga aag ctc cta gaa ctg ata      192
 Tyr Leu Glu Asn Pro Lys Asp Ser Ser Arg Lys Leu Leu Glu Leu Ile
      50                  55                  60

 aaa gaa ttc agc aaa gtt tct gaa tac aaa att aat gta tac aaa tca      240
 Lys Glu Phe Ser Lys Val Ser Glu Tyr Lys Ile Asn Val Tyr Lys Ser
  65                  70                  75                  80

 gta gct ctt cta tac acc aac agc gac caa gct gag aaa caa atc aag      288
 Val Ala Leu Leu Tyr Thr Asn Ser Asp Gln Ala Glu Lys Gln Ile Lys
                  85                  90                  95

 aac tca ata cct ttt aca ata gct gca aaa ata aaa taa                  327
 Asn Ser Ile Pro Phe Thr Ile Ala Ala Lys Ile Lys 
             100                 105





      <210> 313
      <211> 1038
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1038)

      <400> 313
  atg ctg ctg cta gtc tgg ggg tcg gtc atc aga gta ggg aag gcc ttc      48
  Met Leu Leu Leu Val Trp Gly Ser Val Ile Arg Val Gly Lys Ala Phe
    1               5                  10                  15

 cga gaa gac agt ggg ggg ctt ctg ttc cgg gaa gtg gct ccc aag aaa       96
 Arg Glu Asp Ser Gly Gly Leu Leu Phe Arg Glu Val Ala Pro Lys Lys
              20                  25                  30

 tta ctg gtg gat tgt tgg tgc tct gag ggt gaa gag gtg aag gag gaa      144
 Leu Leu Val Asp Cys Trp Cys Ser Glu Gly Glu Glu Val Lys Glu Glu
          35                  40                  45

 gat aaa aag gag cag ccg cag ctt tcc ggt gta gcc ccc tct gct ctg      192
 Asp Lys Lys Glu Gln Pro Gln Leu Ser Gly Val Ala Pro Ser Ala Leu
      50                  55                  60

 ccc cgt tgc cca gac acc cgg cgt tgg gca tca atg gag cac aac aca      240
 Pro Arg Cys Pro Asp Thr Arg Arg Trp Ala Ser Met Glu His Asn Thr
  65                  70                  75                  80

 cat gct gct ccc ttc acg ggt gag acg act gtt cca gag cac gtg tgg      288
 His Ala Ala Pro Phe Thr Gly Glu Thr Thr Val Pro Glu His Val Trp
                  85                  90                  95

 agt cca agc caa gtg aag ccc ctc tgt gct ggc act gtc tgg cct ctg      336
 Ser Pro Ser Gln Val Lys Pro Leu Cys Ala Gly Thr Val Trp Pro Leu
             100                 105                 110

 acc ccg gct ggc aca ggt gtt tgc agc cag cgg gat cag cag ctc aag      384
 Thr Pro Ala Gly Thr Gly Val Cys Ser Gln Arg Asp Gln Gln Leu Lys
         115                 120                 125

 ctc agg agc ctg gcg act gca ggc tcc ccc cag acc cat gga cga aca      432
 Leu Arg Ser Leu Ala Thr Ala Gly Ser Pro Gln Thr His Gly Arg Thr
     130                 135                 140

 agg tca cca gcc ggg acg ctc tgg ggt ggc gtg gtc tcc agg ctc ttc      480
 Arg Ser Pro Ala Gly Thr Leu Trp Gly Gly Val Val Ser Arg Leu Phe
 145                 150                 155                 160

 ctg tac gac ttt gga aaa cag gtt ggt ggc tgt gga cgg cct cag cac      528
 Leu Tyr Asp Phe Gly Lys Gln Val Gly Gly Cys Gly Arg Pro Gln His
                 165                 170                 175

 aga ggg aca cgg gtc agc cag ctc ctg ctg cca atg tcc tgt gca gcc      576
 Arg Gly Thr Arg Val Ser Gln Leu Leu Leu Pro Met Ser Cys Ala Ala
             180                 185                 190

 cct gcc cct ggc tcc atc ctg aac cca cgg gct gag cca aag cag cca      624
 Pro Ala Pro Gly Ser Ile Leu Asn Pro Arg Ala Glu Pro Lys Gln Pro
         195                 200                 205

 aac aag gga gct ggc gat gcg gga ctg cag ggc ggg gcg cag cag cgg      672
 Asn Lys Gly Ala Gly Asp Ala Gly Leu Gln Gly Gly Ala Gln Gln Arg
     210                 215                 220

 aag gac aga gca gcc cct cgg gtt tca ccc ttg acc atc tca gta aga      720
 Lys Asp Arg Ala Ala Pro Arg Val Ser Pro Leu Thr Ile Ser Val Arg
 225                 230                 235                 240

 aaa ccc aga gac ggc ctg cag agg gag gag gaa cag ggt gct gta ctg      768
 Lys Pro Arg Asp Gly Leu Gln Arg Glu Glu Glu Gln Gly Ala Val Leu
                 245                 250                 255

 aga tgg aag gag agg gcg ccc gag ctc tgc tcc cgg gct tgc gcc tgg      816
 Arg Trp Lys Glu Arg Ala Pro Glu Leu Cys Ser Arg Ala Cys Ala Trp
             260                 265                 270

 cct gga gtg gac ttg gcc cct cac ttc tcc ggc tcc ggg agg gcc ctg      864
 Pro Gly Val Asp Leu Ala Pro His Phe Ser Gly Ser Gly Arg Ala Leu
         275                 280                 285

 cta atg gcc cag gac tct ctg gtg cag cag cat tct gtg cag gtg ggg      912
 Leu Met Ala Gln Asp Ser Leu Val Gln Gln His Ser Val Gln Val Gly
     290                 295                 300

 ctg ggc cag acc aag cgg ctg ccg gat ggg cgc ctg gct gca ctg ctg      960
 Leu Gly Gln Thr Lys Arg Leu Pro Asp Gly Arg Leu Ala Ala Leu Leu
 305                 310                 315                 320

 acg gcc gag agc gct gcc gca gct gtg tcc cgc gat ggc agc cag gag     1008
 Thr Ala Glu Ser Ala Ala Ala Ala Val Ser Arg Asp Gly Ser Gln Glu
                 325                 330                 335

 agc ctg cag cag gaa ggc tgg tgc cgg tga                             1038
 Ser Leu Gln Gln Glu Gly Trp Cys Arg 
             340                 345





      <210> 314
      <211> 963
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(963)

      <400> 314
  atg agc ctc cct gcc aaa ctg cta tgc ttg ctg cag gca gtg cac att      48
  Met Ser Leu Pro Ala Lys Leu Leu Cys Leu Leu Gln Ala Val His Ile
    1               5                  10                  15

 gac cct gcc ctt gat ggc cac caa ccc aga gat ggt gtc ctg gtt cag       96
 Asp Pro Ala Leu Asp Gly His Gln Pro Arg Asp Gly Val Leu Val Gln
              20                  25                  30

 agc cag gct gcc caa gtc aac tcc aga gag cag gaa ttc aaa gga aac      144
 Ser Gln Ala Ala Gln Val Asn Ser Arg Glu Gln Glu Phe Lys Gly Asn
          35                  40                  45

 agt cac tct ctc act gtc tct ctg cag ctg act aca ctt tcc cga gac      192
 Ser His Ser Leu Thr Val Ser Leu Gln Leu Thr Thr Leu Ser Arg Asp
      50                  55                  60

 aag cag gag ggc tgt gga ggt ttc agt ggg gga aat cca gct ctg tat      240
 Lys Gln Glu Gly Cys Gly Gly Phe Ser Gly Gly Asn Pro Ala Leu Tyr
  65                  70                  75                  80

 gct aag tac ctg caa tgt gtc agg gct gca ggc tct gag ata gat gcc      288
 Ala Lys Tyr Leu Gln Cys Val Arg Ala Ala Gly Ser Glu Ile Asp Ala
                  85                  90                  95

 tgg gac gga gac gaa caa acc aca gtc cct acc cac tta atc tca gtc      336
 Trp Asp Gly Asp Glu Gln Thr Thr Val Pro Thr His Leu Ile Ser Val
             100                 105                 110

 aag tgg aga gtc caa cat gtg tca aat acc gca ata cct acc gta cac      384
 Lys Trp Arg Val Gln His Val Ser Asn Thr Ala Ile Pro Thr Val His
         115                 120                 125

 tat gtg cag cca cag aag act gta aga gga ata gat gaa gaa agg cca      432
 Tyr Val Gln Pro Gln Lys Thr Val Arg Gly Ile Asp Glu Glu Arg Pro
     130                 135                 140

 att cca ccg tgg gag aca aag gat agt ttc atg ata gag cct ctt gga      480
 Ile Pro Pro Trp Glu Thr Lys Asp Ser Phe Met Ile Glu Pro Leu Gly
 145                 150                 155                 160

 gtt ggg ttc cgc aac ttg cac ctg cat gca gct agg atc ttc aaa gag      528
 Val Gly Phe Arg Asn Leu His Leu His Ala Ala Arg Ile Phe Lys Glu
                 165                 170                 175

 ctg ctt ccc act gag ctt ccg aaa gga tgc cag tgg gtt caa cag cta      576
 Leu Leu Pro Thr Glu Leu Pro Lys Gly Cys Gln Trp Val Gln Gln Leu
             180                 185                 190

 aag tcc agc gag gac agc ctt gaa gaa ccc ttc cag ttc aag cac gtg      624
 Lys Ser Ser Glu Asp Ser Leu Glu Glu Pro Phe Gln Phe Lys His Val
         195                 200                 205

 ttc atc ctc cca ttg gtc att cat ctg tca aaa acg cac caa atc atc      672
 Phe Ile Leu Pro Leu Val Ile His Leu Ser Lys Thr His Gln Ile Ile
     210                 215                 220

 ttg gat gcg ctg agc tct atg cct gcc cta ggc tca ttc ccg cct tcc      720
 Leu Asp Ala Leu Ser Ser Met Pro Ala Leu Gly Ser Phe Pro Pro Ser
 225                 230                 235                 240

 cag gaa tct cgg cat gcc atg aag ggt tac ttg aat gct att gaa cag      768
 Gln Glu Ser Arg His Ala Met Lys Gly Tyr Leu Asn Ala Ile Glu Gln
                 245                 250                 255

 tcg tgg gaa gct aaa gct act tcc cac tca ggg agt cct ttc aca cgg      816
 Ser Trp Glu Ala Lys Ala Thr Ser His Ser Gly Ser Pro Phe Thr Arg
             260                 265                 270

 gaa aag tca gtg gaa gag gaa gat tgg gtg tgt ttc ttt ctg atc aaa      864
 Glu Lys Ser Val Glu Glu Glu Asp Trp Val Cys Phe Phe Leu Ile Lys
         275                 280                 285

 cgg ggc acg gat acc ctg gga cct atg gag atc atc acc tgc ttc agg      912
 Arg Gly Thr Asp Thr Leu Gly Pro Met Glu Ile Ile Thr Cys Phe Arg
     290                 295                 300

 gat gcg gag ggg agt att gcc aat cgc ctg ttt cac cct cca ccg act      960
 Asp Ala Glu Gly Ser Ile Ala Asn Arg Leu Phe His Pro Pro Pro Thr
 305                 310                 315                 320

 tga                                                                  963
 






      <210> 315
      <211> 195
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(195)

      <400> 315
  atg caa caa gag tct gcc tct cac ctg cgc aca gag aga tac ttc ttg      48
  Met Gln Gln Glu Ser Ala Ser His Leu Arg Thr Glu Arg Tyr Phe Leu
    1               5                  10                  15

 cat cag ccc ctg gcc ctt tgg aag cca agc ttc atc cta ttt act cag       96
 His Gln Pro Leu Ala Leu Trp Lys Pro Ser Phe Ile Leu Phe Thr Gln
              20                  25                  30

 ctc tta tgg tca gag ctg agc tct ttt gtg gac cac aca tat ggc aac      144
 Leu Leu Trp Ser Glu Leu Ser Ser Phe Val Asp His Thr Tyr Gly Asn
          35                  40                  45

 caa gaa cca cac aca gtt tca ctt tat caa tta ggt gtt gtt cac aag      192
 Gln Glu Pro His Thr Val Ser Leu Tyr Gln Leu Gly Val Val His Lys
      50                  55                  60

 tag                                                                  195
 






      <210> 316
      <211> 375
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(375)

      <400> 316
  atg gac aaa cgg aag gcc tct gga ggc ccc ttt ccc aaa cca cag cca      48
  Met Asp Lys Arg Lys Ala Ser Gly Gly Pro Phe Pro Lys Pro Gln Pro
    1               5                  10                  15

 atc acc aat ttc tac ctg tgt tta agg ttg ttc atg ttc ttc tta tcg       96
 Ile Thr Asn Phe Tyr Leu Cys Leu Arg Leu Phe Met Phe Phe Leu Ser
              20                  25                  30

 atc ccc acc ccg acc ccc acc ata aag gct tct atg ggg ccc atc ctg      144
 Ile Pro Thr Pro Thr Pro Thr Ile Lys Ala Ser Met Gly Pro Ile Leu
          35                  40                  45

 ttt ggt gat aaa ttt gta ggc acg cat ctc cag ctt tca cag att cca      192
 Phe Gly Asp Lys Phe Val Gly Thr His Leu Gln Leu Ser Gln Ile Pro
      50                  55                  60

 gcc agg acc ctc gag cac cta cag cat aat gcc cca cca gtc act act      240
 Ala Arg Thr Leu Glu His Leu Gln His Asn Ala Pro Pro Val Thr Thr
  65                  70                  75                  80

 aga tac ttt ctg aaa gaa cag gaa agt gaa aag tct acc ata tcg gag      288
 Arg Tyr Phe Leu Lys Glu Gln Glu Ser Glu Lys Ser Thr Ile Ser Glu
                  85                  90                  95

 agc ttt aag cag tgt aca tgc aca agt atc tgt aag caa atc atc cag      336
 Ser Phe Lys Gln Cys Thr Cys Thr Ser Ile Cys Lys Gln Ile Ile Gln
             100                 105                 110

 aag aaa ata cca acc aac tgt cta ata aac tgt tcc taa                  375
 Lys Lys Ile Pro Thr Asn Cys Leu Ile Asn Cys Ser 
         115                 120





      <210> 317
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 317
  atg ggg aag gcc atg ttg cag ctg ctg atc aga gca cat tgg acg gtg      48
  Met Gly Lys Ala Met Leu Gln Leu Leu Ile Arg Ala His Trp Thr Val
    1               5                  10                  15

 ttt ccg tgt gaa cat gaa gac aat gct gcc tct gtt tct gtg acg ctg       96
 Phe Pro Cys Glu His Glu Asp Asn Ala Ala Ser Val Ser Val Thr Leu
              20                  25                  30

 tgc tct gat ctt gct gga ggc gaa gtg gtg tca gct gtg ctt aca gga      144
 Cys Ser Asp Leu Ala Gly Gly Glu Val Val Ser Ala Val Leu Thr Gly
          35                  40                  45

 cag tca gtg gtg caa act gag aaa gag atc gat agg tca tca aag cca      192
 Gln Ser Val Val Gln Thr Glu Lys Glu Ile Asp Arg Ser Ser Lys Pro
      50                  55                  60

 cct gct tgc ttg gtg gcc cct caa gtt gtc ttc tgc tca gaa gtt ctg      240
 Pro Ala Cys Leu Val Ala Pro Gln Val Val Phe Cys Ser Glu Val Leu
  65                  70                  75                  80

 aga gtt gat gaa agt tat cat cga aag tac cca gtc cag ctc agg cca      288
 Arg Val Asp Glu Ser Tyr His Arg Lys Tyr Pro Val Gln Leu Arg Pro
                  85                  90                  95

 gtc cat att gct gcc aag taa                                          309
 Val His Ile Ala Ala Lys 
             100





      <210> 318
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 318
  atg gtt aaa acg cag att tgt ctt ctc tgt tct cac ttt cct ttc tgc      48
  Met Val Lys Thr Gln Ile Cys Leu Leu Cys Ser His Phe Pro Phe Cys
    1               5                  10                  15

 cag ctg gac ata gag gat gca gag ggc ctg gag gat aat gga tca tgg       96
 Gln Leu Asp Ile Glu Asp Ala Glu Gly Leu Glu Asp Asn Gly Ser Trp
              20                  25                  30

 gtg aaa gaa gtt tgg gtg tct gaa tta ctg cat gag gct gtt cct acc      144
 Val Lys Glu Val Trp Val Ser Glu Leu Leu His Glu Ala Val Pro Thr
          35                  40                  45

 ctg gta aag aaa ggc aca tta ttt tca agt tcc tgt tat cgt gct ttg      192
 Leu Val Lys Lys Gly Thr Leu Phe Ser Ser Ser Cys Tyr Arg Ala Leu
      50                  55                  60

 agg tgc act gaa ctg cag caa acc cag ggg atc caa ggc tac gtt gaa      240
 Arg Cys Thr Glu Leu Gln Gln Thr Gln Gly Ile Gln Gly Tyr Val Glu
  65                  70                  75                  80

 aag cct ttg acc aca gtg cag gga gca gaa gac att aat gac gtg atg      288
 Lys Pro Leu Thr Thr Val Gln Gly Ala Glu Asp Ile Asn Asp Val Met
                  85                  90                  95

 tcg aca cag ccc gca ctc agg atc ctc cag gaa aag aac aca gag ata      336
 Ser Thr Gln Pro Ala Leu Arg Ile Leu Gln Glu Lys Asn Thr Glu Ile
             100                 105                 110

 acc ccg gat cga tgg tgt ttc ctc agt tcc tca ata aaa ctt gct cat      384
 Thr Pro Asp Arg Trp Cys Phe Leu Ser Ser Ser Ile Lys Leu Ala His
         115                 120                 125

 caa gca aga aat ttt gtt gaa gag ctg gct tag                          417
 Gln Ala Arg Asn Phe Val Glu Glu Leu Ala 
     130                 135





      <210> 319
      <211> 183
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(183)

      <400> 319
  atg aca ggg ctg aga ttc ttc ctg gaa ctt ttt gaa aca gca aca ctg      48
  Met Thr Gly Leu Arg Phe Phe Leu Glu Leu Phe Glu Thr Ala Thr Leu
    1               5                  10                  15

 ggt gcg gtc ttt acc agt ggg agc ttg ttc aca gtg cat gca cag aaa       96
 Gly Ala Val Phe Thr Ser Gly Ser Leu Phe Thr Val His Ala Gln Lys
              20                  25                  30

 cct gta gac cat ggg tta ggc tct tgc aag act tcc ctg aaa gat cgg      144
 Pro Val Asp His Gly Leu Gly Ser Cys Lys Thr Ser Leu Lys Asp Arg
          35                  40                  45

 acc tgg tca ctg aca aga ttt gtc tgc att tcc cct tga                  183
 Thr Trp Ser Leu Thr Arg Phe Val Cys Ile Ser Pro 
      50                  55                  60





      <210> 320
      <211> 363
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(363)

      <400> 320
  atg tgc acc acc ctt ttc ctg ctc agc acc ctg gcc atg ctc tgg cgc      48
  Met Cys Thr Thr Leu Phe Leu Leu Ser Thr Leu Ala Met Leu Trp Arg
    1               5                  10                  15

 cgc cga ttt gcc aac cga gtc caa cca gag ccc agc gac gtg gat ggg       96
 Arg Arg Phe Ala Asn Arg Val Gln Pro Glu Pro Ser Asp Val Asp Gly
              20                  25                  30

 gca gct agg ggc agc agc ttg gat gcg gac cct cag tcc tca ggc agc      144
 Ala Ala Arg Gly Ser Ser Leu Asp Ala Asp Pro Gln Ser Ser Gly Ser
          35                  40                  45

 cag ggg cag ggc cct ggg gag agg aca gga tgg cag cca gca gcc cag      192
 Gln Gly Gln Gly Pro Gly Glu Arg Thr Gly Trp Gln Pro Ala Ala Gln
      50                  55                  60

 ctg gag atg cgg agc ctg gtg cag tca gcc tca gtt tcc aaa gcc gga      240
 Leu Glu Met Arg Ser Leu Val Gln Ser Ala Ser Val Ser Lys Ala Gly
  65                  70                  75                  80

 aaa gga tcc tct agt agc cac ggt gtg gca gct gct ctg aac cag gac      288
 Lys Gly Ser Ser Ser Ser His Gly Val Ala Ala Ala Leu Asn Gln Asp
                  85                  90                  95

 ctg gac ccg gac cca aag tgc cat gtc ttt aat cat atc ctg ctg aga      336
 Leu Asp Pro Asp Pro Lys Cys His Val Phe Asn His Ile Leu Leu Arg
             100                 105                 110

 gcc cag tct aga gca tca ttc ctc taa                                  363
 Ala Gln Ser Arg Ala Ser Phe Leu 
         115                 120





      <210> 321
      <211> 528
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(528)

      <400> 321
  atg gcc ctg tca gct acc ctg aag ctt cag atc tac ttc ctg gct cag      48
  Met Ala Leu Ser Ala Thr Leu Lys Leu Gln Ile Tyr Phe Leu Ala Gln
    1               5                  10                  15

 acc acc tgc aac aca ctg gtt tgg cat cta gcg ggt tgt gct tgc aga       96
 Thr Thr Cys Asn Thr Leu Val Trp His Leu Ala Gly Cys Ala Cys Arg
              20                  25                  30

 aca gca ggc tgg ctc cgt gca cct gct cag tgg ggc tgg gct tta gca      144
 Thr Ala Gly Trp Leu Arg Ala Pro Ala Gln Trp Gly Trp Ala Leu Ala
          35                  40                  45

 acc tgc att gag gct gct ctt ctt aac ttt tct cta act tgc ttc atg      192
 Thr Cys Ile Glu Ala Ala Leu Leu Asn Phe Ser Leu Thr Cys Phe Met
      50                  55                  60

 aaa gtt aat tct gct ggg acc cca cga ggc agc gga gag ccc act ctg      240
 Lys Val Asn Ser Ala Gly Thr Pro Arg Gly Ser Gly Glu Pro Thr Leu
  65                  70                  75                  80

 ccc atg att ggt gcc ctg ggc tgg cac gca gag ttt aat gga gga gcc      288
 Pro Met Ile Gly Ala Leu Gly Trp His Ala Glu Phe Asn Gly Gly Ala
                  85                  90                  95

 cgg gag aga ggg atg cct gag aac cag gga tat tac ctg gca ctt gtc      336
 Arg Glu Arg Gly Met Pro Glu Asn Gln Gly Tyr Tyr Leu Ala Leu Val
             100                 105                 110

 cag tct ttc tgc agt caa cat cgc cca gat tcc atg cag aac cct ttg      384
 Gln Ser Phe Cys Ser Gln His Arg Pro Asp Ser Met Gln Asn Pro Leu
         115                 120                 125

 cag act cct gag gag gta cag aca agg agt gtc cct gtc ctc atg gtg      432
 Gln Thr Pro Glu Glu Val Gln Thr Arg Ser Val Pro Val Leu Met Val
     130                 135                 140

 cta cat gaa aag gta cag aca agg agt gtc cct gtc ctc atg gtg cta      480
 Leu His Glu Lys Val Gln Thr Arg Ser Val Pro Val Leu Met Val Leu
 145                 150                 155                 160

 cat gaa aag gca agt gac cca aca ggc agc att gga gaa agt gcc taa      528
 His Glu Lys Ala Ser Asp Pro Thr Gly Ser Ile Gly Glu Ser Ala 
                 165                 170                 175





      <210> 322
      <211> 528
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(528)

      <400> 322
  atg acc aag gcc ctg gga gcc atg aag ata gag gcc aca ctg gac att      48
  Met Thr Lys Ala Leu Gly Ala Met Lys Ile Glu Ala Thr Leu Asp Ile
    1               5                  10                  15

 tcc agc tgg gca gag aga gga agt tgt tcc ctg gcc ttt ctc att ccc       96
 Ser Ser Trp Ala Glu Arg Gly Ser Cys Ser Leu Ala Phe Leu Ile Pro
              20                  25                  30

 cag tta ttt cct atg ctt act ccc tgc tct aaa ctc cac tgg ctg tcc      144
 Gln Leu Phe Pro Met Leu Thr Pro Cys Ser Lys Leu His Trp Leu Ser
          35                  40                  45

 tta ttg ctt gca tgg act tca ata tcg cag tac atc acc ggt tct ctc      192
 Leu Leu Leu Ala Trp Thr Ser Ile Ser Gln Tyr Ile Thr Gly Ser Leu
      50                  55                  60

 cta gaa gca acc acg tct ttg gga gca aga agt ggc ctt ctc agt act      240
 Leu Glu Ala Thr Thr Ser Leu Gly Ala Arg Ser Gly Leu Leu Ser Thr
  65                  70                  75                  80

 ttt gga gga tcc act gga cga atg atg ctg aaa gcc agt gct gag gag      288
 Phe Gly Gly Ser Thr Gly Arg Met Met Leu Lys Ala Ser Ala Glu Glu
                  85                  90                  95

 atg acc aag tac cac agt gat gac tac att aaa tcc ttg cac tcc att      336
 Met Thr Lys Tyr His Ser Asp Asp Tyr Ile Lys Ser Leu His Ser Ile
             100                 105                 110

 cat cct gat aac atg tct gag tac agc cag cag gca cag aga ttc aac      384
 His Pro Asp Asn Met Ser Glu Tyr Ser Gln Gln Ala Gln Arg Phe Asn
         115                 120                 125

 att ggt gag gac tgt cca gta ttt cat ggc ctc ttt gag ttt cgt cag      432
 Ile Gly Glu Asp Cys Pro Val Phe His Gly Leu Phe Glu Phe Arg Gln
     130                 135                 140

 ttg tct gtg ggc ggc tct gtg gca agt tct gtg aaa ctt aat gag tgg      480
 Leu Ser Val Gly Gly Ser Val Ala Ser Ser Val Lys Leu Asn Glu Trp
 145                 150                 155                 160

 cag aca gac atc acc atg aac cag act gca cca tgc aaa gaa gtc tga      528
 Gln Thr Asp Ile Thr Met Asn Gln Thr Ala Pro Cys Lys Glu Val 
                 165                 170                 175





      <210> 323
      <211> 495
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(495)

      <400> 323
  atg gga tgg gta tgg ggt ctg gtt cgt ttc acc tta gaa ctt ttt cac      48
  Met Gly Trp Val Trp Gly Leu Val Arg Phe Thr Leu Glu Leu Phe His
    1               5                  10                  15

 act gat aac gag gag gaa caa cag tat agc gaa gta aca gaa gag gtt       96
 Thr Asp Asn Glu Glu Glu Gln Gln Tyr Ser Glu Val Thr Glu Glu Val
              20                  25                  30

 aca gag cat gtt tat ttg cca gct gaa gct aaa gcg gca aag gaa gga      144
 Thr Glu His Val Tyr Leu Pro Ala Glu Ala Lys Ala Ala Lys Glu Gly
          35                  40                  45

 gag ttt cat ccc tac cct tct gca tcc cct cat tat tat ttt gaa gaa      192
 Glu Phe His Pro Tyr Pro Ser Ala Ser Pro His Tyr Tyr Phe Glu Glu
      50                  55                  60

 aat gac tcc cca gat ctt tct ttt ccg gag gac act ggg cga aaa gta      240
 Asn Asp Ser Pro Asp Leu Ser Phe Pro Glu Asp Thr Gly Arg Lys Val
  65                  70                  75                  80

 gtt gcc cca gca gga att cag caa gct aga caa gag ggt gat tta gag      288
 Val Ala Pro Ala Gly Ile Gln Gln Ala Arg Gln Glu Gly Asp Leu Glu
                  85                  90                  95

 gct tgg cag ttc cct gtt aga ata cac ccc cca gat caa cag gga agt      336
 Ala Trp Gln Phe Pro Val Arg Ile His Pro Pro Asp Gln Gln Gly Ser
             100                 105                 110

 att aca gct aca ttt gag cct ttt cct ttt aaa tta ctc aga gaa tta      384
 Ile Thr Ala Thr Phe Glu Pro Phe Pro Phe Lys Leu Leu Arg Glu Leu
         115                 120                 125

 aaa caa gca ata aat gag tat gga cca ggt tct cct tta gta att gga      432
 Lys Gln Ala Ile Asn Glu Tyr Gly Pro Gly Ser Pro Leu Val Ile Gly
     130                 135                 140

 ctg tta aag aat gtt act gtt tcc agt cag atg att cct act gac tgg      480
 Leu Leu Lys Asn Val Thr Val Ser Ser Gln Met Ile Pro Thr Asp Trp
 145                 150                 155                 160

 gac gct ctt act tga                                                  495
 Asp Ala Leu Thr 






      <210> 324
      <211> 831
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(831)

      <400> 324
  atg atg cta ctt ctg ctg gcc ctg ctg ggg gct ggc cta ctg ggg gct      48
  Met Met Leu Leu Leu Leu Ala Leu Leu Gly Ala Gly Leu Leu Gly Ala
    1               5                  10                  15

 tcc ctg ctc acc tcg tgg cat gct cca gcc cgg aac aag atc ccc agg       96
 Ser Leu Leu Thr Ser Trp His Ala Pro Ala Arg Asn Lys Ile Pro Arg
              20                  25                  30

 gcc cag aag tgg agg gag gag cca gat ctg gac ccc aag cca atc ctg      144
 Ala Gln Lys Trp Arg Glu Glu Pro Asp Leu Asp Pro Lys Pro Ile Leu
          35                  40                  45

 gag ctg ccc ctg gca gag ctg gcc cag cag ctt cgg acc gaa gag ctg      192
 Glu Leu Pro Leu Ala Glu Leu Ala Gln Gln Leu Arg Thr Glu Glu Leu
      50                  55                  60

 agt ctg gag agc atc ctc tgt agc tac tta aag cag gca ctg aag gtg      240
 Ser Leu Glu Ser Ile Leu Cys Ser Tyr Leu Lys Gln Ala Leu Lys Val
  65                  70                  75                  80

 cac cag gag gtg aac tgc ctg atg gat ttc ctg ggg gaa tgt gag gag      288
 His Gln Glu Val Asn Cys Leu Met Asp Phe Leu Gly Glu Cys Glu Glu
                  85                  90                  95

 gaa ctg cag gca tta aag aag ctt aag aag agt gag aga ggc ctt ctc      336
 Glu Leu Gln Ala Leu Lys Lys Leu Lys Lys Ser Glu Arg Gly Leu Leu
             100                 105                 110

 tat ggg gtc ccc atg agc ctc aag gac acc tat gac agc atg ttc ctg      384
 Tyr Gly Val Pro Met Ser Leu Lys Asp Thr Tyr Asp Ser Met Phe Leu
         115                 120                 125

 gag aag cct gcg acc aag gac ggg gtc att atg aaa gtg ctc aag gcc      432
 Glu Lys Pro Ala Thr Lys Asp Gly Val Ile Met Lys Val Leu Lys Ala
     130                 135                 140

 caa gga gcc atc ccc ttt gtt aag acc aac atc cca ctg acg ctg ctc      480
 Gln Gly Ala Ile Pro Phe Val Lys Thr Asn Ile Pro Leu Thr Leu Leu
 145                 150                 155                 160

 agg tct ctg aag cgg gct agc tgg gct ttg aat gcg gca act ccc atc      528
 Arg Ser Leu Lys Arg Ala Ser Trp Ala Leu Asn Ala Ala Thr Pro Ile
                 165                 170                 175

 tat ggc cag atg ttg agc cca ctg aac tta aag aag aca tgt ggg ggc      576
 Tyr Gly Gln Met Leu Ser Pro Leu Asn Leu Lys Lys Thr Cys Gly Gly
             180                 185                 190

 tcc tca ggg gtg acc acg gtg gct ggc ccc atg gcc cag gac gtg gag      624
 Ser Ser Gly Val Thr Thr Val Ala Gly Pro Met Ala Gln Asp Val Glu
         195                 200                 205

 agc ctg gcg ctg tgc ctg caa gcc ctg ctg agt gaa gac atg tac cga      672
 Ser Leu Ala Leu Cys Leu Gln Ala Leu Leu Ser Glu Asp Met Tyr Arg
     210                 215                 220

 ctg gac ccc act gtg ctc cag atg ccc ttt agg gag gag gtt tac acc      720
 Leu Asp Pro Thr Val Leu Gln Met Pro Phe Arg Glu Glu Val Tyr Thr
 225                 230                 235                 240

 agt aac cgg ccc ctt cga att ggc tac tat gaa tca gat ggt tac atc      768
 Ser Asn Arg Pro Leu Arg Ile Gly Tyr Tyr Glu Ser Asp Gly Tyr Ile
                 245                 250                 255

 cag cca tcc cct agc atg gcc agg gct gtg cag ctc acc tcc tgg ctg      816
 Gln Pro Ser Pro Ser Met Ala Arg Ala Val Gln Leu Thr Ser Trp Leu
             260                 265                 270

 ctc cag gat gct tga                                                  831
 Leu Gln Asp Ala 
         275





      <210> 325
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 325
  atg tgc cgg ggg aag aca ttt ccc tcc atc cac ctg tgg acc cgg ctc      48
  Met Cys Arg Gly Lys Thr Phe Pro Ser Ile His Leu Trp Thr Arg Leu
    1               5                  10                  15

 ctg tcg gcc ctg gct ggc ctc ctc tat gcc tcg gcc att gtg gcc cac       96
 Leu Ser Ala Leu Ala Gly Leu Leu Tyr Ala Ser Ala Ile Val Ala His
              20                  25                  30

 gac cgg cac cct gag tac ctg ctg cgg gcc aca ccc tgg ttc ctg acc      144
 Asp Arg His Pro Glu Tyr Leu Leu Arg Ala Thr Pro Trp Phe Leu Thr
          35                  40                  45

 tcc ctc ggc cgt gcg gca ctg gac ctc gct att att ttc ctt tcg tgt      192
 Ser Leu Gly Arg Ala Ala Leu Asp Leu Ala Ile Ile Phe Leu Ser Cys
      50                  55                  60

 gtg atg aag agc aag atg aga cag gcc tta gga ttt gcc aag gaa gcc      240
 Val Met Lys Ser Lys Met Arg Gln Ala Leu Gly Phe Ala Lys Glu Ala
  65                  70                  75                  80

 aga gag agc cct gac acc caa gcc ctt ttg acc tgt gca gag aaa gag      288
 Arg Glu Ser Pro Asp Thr Gln Ala Leu Leu Thr Cys Ala Glu Lys Glu
                  85                  90                  95

 gaa gaa aac cag gag gtg agg aac gag gac aag gtc tct ctg gct gga      336
 Glu Glu Asn Gln Glu Val Arg Asn Glu Asp Lys Val Ser Leu Ala Gly
             100                 105                 110

 aaa ctc tgg tcc cag caa cag tat ctt gag aaa cag cag gat act gcg      384
 Lys Leu Trp Ser Gln Gln Gln Tyr Leu Glu Lys Gln Gln Asp Thr Ala
         115                 120                 125

 gac gga cgt gtg aaa gct gcc tgc cga gtg ttc tct gca ggc gac tca      432
 Asp Gly Arg Val Lys Ala Ala Cys Arg Val Phe Ser Ala Gly Asp Ser
     130                 135                 140

 gac agc tgt cct gtc tcg ctg agg gaa tag                              462
 Asp Ser Cys Pro Val Ser Leu Arg Glu 
 145                 150





      <210> 326
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 326
  atg agg gca ggc att ctt gtc tgt ttt gtc tac ggt gtg ccc cta atg      48
  Met Arg Ala Gly Ile Leu Val Cys Phe Val Tyr Gly Val Pro Leu Met
    1               5                  10                  15

 cct ccc cca aat gct gca gag aag ctg tca aaa gtg aag gca aag gaa       96
 Pro Pro Pro Asn Ala Ala Glu Lys Leu Ser Lys Val Lys Ala Lys Glu
              20                  25                  30

 gaa tca tgg gat gcg ata gtg gga agt gaa gac tat gaa ctc aat tgt      144
 Glu Ser Trp Asp Ala Ile Val Gly Ser Glu Asp Tyr Glu Leu Asn Cys
          35                  40                  45

 gtc cca tgt atc tgt gaa ccc tct gct gtt ttg cga ctt gcg tcc cta      192
 Val Pro Cys Ile Cys Glu Pro Ser Ala Val Leu Arg Leu Ala Ser Leu
      50                  55                  60

 aag gat gcc acc cag atg aac aac gca gtg ccc acc tct cct ctg ctc      240
 Lys Asp Ala Thr Gln Met Asn Asn Ala Val Pro Thr Ser Pro Leu Leu
  65                  70                  75                  80

 cag cag atg ggc cat cca cat tcg tac ccg aac ctg ggc cag atc tcc      288
 Gln Gln Met Gly His Pro His Ser Tyr Pro Asn Leu Gly Gln Ile Ser
                  85                  90                  95

 aac ccc tat gaa cag cag cca cca gga aaa gag ctc aac aag tac gcc      336
 Asn Pro Tyr Glu Gln Gln Pro Pro Gly Lys Glu Leu Asn Lys Tyr Ala
             100                 105                 110

 tcc tta aag gca gtc ggc att taa                                      360
 Ser Leu Lys Ala Val Gly Ile 
         115





      <210> 327
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 327
  atg aat ttg ctg gag tac ttc cta gca ctg acc tcc ttc att ctg cgt      48
  Met Asn Leu Leu Glu Tyr Phe Leu Ala Leu Thr Ser Phe Ile Leu Arg
    1               5                  10                  15

 tgt tct tac tgg atc ttt cca tca gcc aac aat atg gaa gta cca ata       96
 Cys Ser Tyr Trp Ile Phe Pro Ser Ala Asn Asn Met Glu Val Pro Ile
              20                  25                  30

 caa ggt caa atc att cct gga ttc atc tgg agt tgc tta aaa gtt aaa      144
 Gln Gly Gln Ile Ile Pro Gly Phe Ile Trp Ser Cys Leu Lys Val Lys
          35                  40                  45

 tca ttg gaa ttt ttg atg ata cct ttt cta tat gga tta caa ttt gat      192
 Ser Leu Glu Phe Leu Met Ile Pro Phe Leu Tyr Gly Leu Gln Phe Asp
      50                  55                  60

 cgc tgg gaa ttc tcc acc tta aag aag acc ttg att ctc atg gct ggc      240
 Arg Trp Glu Phe Ser Thr Leu Lys Lys Thr Leu Ile Leu Met Ala Gly
  65                  70                  75                  80

 caa ttt cag tgg atc ttg gcc agc ctc agt ggt ctc agg ttc tgc ctc      288
 Gln Phe Gln Trp Ile Leu Ala Ser Leu Ser Gly Leu Arg Phe Cys Leu
                  85                  90                  95

 ctg ttc tta cag aat aat ctt gga tcc taa                              318
 Leu Phe Leu Gln Asn Asn Leu Gly Ser 
             100                 105





      <210> 328
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 328
  atg gtg gtt tgc ctt ctg ctc aga ttc tgc aag acc cat ggg cga gca      48
  Met Val Val Cys Leu Leu Leu Arg Phe Cys Lys Thr His Gly Arg Ala
    1               5                  10                  15

 atc ctg ctt tat tcg aag gct ctc aga tac gat ggg tat cgg aca ctc       96
 Ile Leu Leu Tyr Ser Lys Ala Leu Arg Tyr Asp Gly Tyr Arg Thr Leu
              20                  25                  30

 tgt gta gcc ttc aaa gaa att gct cca gat gat tat gaa aga att aac      144
 Cys Val Ala Phe Lys Glu Ile Ala Pro Asp Asp Tyr Glu Arg Ile Asn
          35                  40                  45

 agc cag ctc ata gag gca aaa atg gcc tta caa gac aga gaa gaa aaa      192
 Ser Gln Leu Ile Glu Ala Lys Met Ala Leu Gln Asp Arg Glu Glu Lys
      50                  55                  60

 atg gaa aaa gtt ttc gat gat att gag aca aac atg aat tta att gga      240
 Met Glu Lys Val Phe Asp Asp Ile Glu Thr Asn Met Asn Leu Ile Gly
  65                  70                  75                  80

 gcc act gca gtt gaa gac aag tac cta gaa aat gat act ctt att att      288
 Ala Thr Ala Val Glu Asp Lys Tyr Leu Glu Asn Asp Thr Leu Ile Ile
                  85                  90                  95

 tta atg acc agt gtt ttg ggt aag ccg gag gac cct tct tgt ccc tga      336
 Leu Met Thr Ser Val Leu Gly Lys Pro Glu Asp Pro Ser Cys Pro 
             100                 105                 110





      <210> 329
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 329
  atg cag gtt cct gca tgg ctg gtt cac tgt gtg atc ttc cta tcc caa      48
  Met Gln Val Pro Ala Trp Leu Val His Cys Val Ile Phe Leu Ser Gln
    1               5                  10                  15

 agc ata gat aca gaa ttg aag ctg gat ccc ctc gga acc gtg agt cga       96
 Ser Ile Asp Thr Glu Leu Lys Leu Asp Pro Leu Gly Thr Val Ser Arg
              20                  25                  30

 ata ttt gat tca agg cgg ttt cag gac atg gat gtt ggc cct aac tcc      144
 Ile Phe Asp Ser Arg Arg Phe Gln Asp Met Asp Val Gly Pro Asn Ser
          35                  40                  45

 atc gcg aac aag tta gcc ccg ccg ggg cgc cct acg gaa cgc ggt ggg      192
 Ile Ala Asn Lys Leu Ala Pro Pro Gly Arg Pro Thr Glu Arg Gly Gly
      50                  55                  60

 ctt ttc aag tgc tca gtc cct ctg cgg aca gtg cga ggc tgc cgg gcc      240
 Leu Phe Lys Cys Ser Val Pro Leu Arg Thr Val Arg Gly Cys Arg Ala
  65                  70                  75                  80

 ggg ctc cgg ggg acc gag act gta cct tcc agc ctt cag cgc cag gcc      288
 Gly Leu Arg Gly Thr Glu Thr Val Pro Ser Ser Leu Gln Arg Gln Ala
                  85                  90                  95

 ggg tgg tcc agg gat ctg gga gcg ccg gcg gtg cgc act gcg ccc agg      336
 Gly Trp Ser Arg Asp Leu Gly Ala Pro Ala Val Arg Thr Ala Pro Arg
             100                 105                 110

 gag agc cgg ttt ggg aac ttc ctg gag cat ctc gag ctt tag              378
 Glu Ser Arg Phe Gly Asn Phe Leu Glu His Leu Glu Leu 
         115                 120                 125





      <210> 330
      <211> 159
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(159)

      <400> 330
  atg gtg aga aaa aag gct gtg gtc tct gct ttt cag agc tgg tgg gtc      48
  Met Val Arg Lys Lys Ala Val Val Ser Ala Phe Gln Ser Trp Trp Val
    1               5                  10                  15

 ctg ttg ggg att ttc atg acc aag att gag aat gtc cac gtg gcc gag       96
 Leu Leu Gly Ile Phe Met Thr Lys Ile Glu Asn Val His Val Ala Glu
              20                  25                  30

 gtc ctg ccc act cag gga acc gtg gac tct tta ggg gtc cag atc aca      144
 Val Leu Pro Thr Gln Gly Thr Val Asp Ser Leu Gly Val Gln Ile Thr
          35                  40                  45

 gag cat gtt ccc tga                                                  159
 Glu His Val Pro 
      50





      <210> 331
      <211> 651
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(651)

      <400> 331
  atg gat gaa agg ttc aac aag tgg ctg ctg acg ccg gtg ctc act ctc      48
  Met Asp Glu Arg Phe Asn Lys Trp Leu Leu Thr Pro Val Leu Thr Leu
    1               5                  10                  15

 ctc ttc gtg gtc atc atg tac cag tac gtg tcc ccc tcc tgc acc agc       96
 Leu Phe Val Val Ile Met Tyr Gln Tyr Val Ser Pro Ser Cys Thr Ser
              20                  25                  30

 tcc tgc acc aac ttc ggg gag cag ccc cgc gcg ggg gag gcc ggc ccg      144
 Ser Cys Thr Asn Phe Gly Glu Gln Pro Arg Ala Gly Glu Ala Gly Pro
          35                  40                  45

 ccc gcc gtc ccg ggt ccc gcc cgc cgg gct cag gcg ccg ccg gag gag      192
 Pro Ala Val Pro Gly Pro Ala Arg Arg Ala Gln Ala Pro Pro Glu Glu
      50                  55                  60

 tgg gag cgg cgg ccc cag ttg ccc ccg ccg ccc cgg ggg ccc ccc gag      240
 Trp Glu Arg Arg Pro Gln Leu Pro Pro Pro Pro Arg Gly Pro Pro Glu
  65                  70                  75                  80

 gga cct cgg ggg gcc gcg gcg ccg gag gag gag gac gag gag ccc gga      288
 Gly Pro Arg Gly Ala Ala Ala Pro Glu Glu Glu Asp Glu Glu Pro Gly
                  85                  90                  95

 gac ccc cgg gag ggg gag gaa gag gag gag gaa gac gag ccg gac ccc      336
 Asp Pro Arg Glu Gly Glu Glu Glu Glu Glu Glu Asp Glu Pro Asp Pro
             100                 105                 110

 gag gcc ccg gaa aac ggc tcc ctg ccc cga ttc gtg ccg cgc ttc aac      384
 Glu Ala Pro Glu Asn Gly Ser Leu Pro Arg Phe Val Pro Arg Phe Asn
         115                 120                 125

 ttc agc ctg aag gac ctg acc cgc ttc gtg gat ttc aac atc aaa ggg      432
 Phe Ser Leu Lys Asp Leu Thr Arg Phe Val Asp Phe Asn Ile Lys Gly
     130                 135                 140

 cgc gac gtg atc gtg ttc ctc cac atc cag aag acg ggg ggc acc act      480
 Arg Asp Val Ile Val Phe Leu His Ile Gln Lys Thr Gly Gly Thr Thr
 145                 150                 155                 160

 ttc ggc cgg cac ctg gtg aag aac atc cgg ctg gag cag cct tgt agc      528
 Phe Gly Arg His Leu Val Lys Asn Ile Arg Leu Glu Gln Pro Cys Ser
                 165                 170                 175

 tgc aaa gcg gtc ctg acc cag agc gac ccc gcg ctc cct gcc cct gcc      576
 Cys Lys Ala Val Leu Thr Gln Ser Asp Pro Ala Leu Pro Ala Pro Ala
             180                 185                 190

 gat ggt ttc ctg gcg tct tca gcg gtt ggc gcc gtg gct ttg ggg agg      624
 Asp Gly Phe Leu Ala Ser Ser Ala Val Gly Ala Val Ala Leu Gly Arg
         195                 200                 205

 gat gag aaa cct ccg gat agt gcc tag                                  651
 Asp Glu Lys Pro Pro Asp Ser Ala 
     210                 215





      <210> 332
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 332
  atg cgc gcg ccc cag ggc cca gcc ctg ttc ctg ctc cgg ctc ctg cgg      48
  Met Arg Ala Pro Gln Gly Pro Ala Leu Phe Leu Leu Arg Leu Leu Arg
    1               5                  10                  15

 gga tgg atg ctt cac gca cct aag tcg cgg aag cgt aga cac ccg gct       96
 Gly Trp Met Leu His Ala Pro Lys Ser Arg Lys Arg Arg His Pro Ala
              20                  25                  30

 ttt ccc gcg tgc tct atc ggg ctc ccc tgg aca cgg agg gtg gag cag      144
 Phe Pro Ala Cys Ser Ile Gly Leu Pro Trp Thr Arg Arg Val Glu Gln
          35                  40                  45

 aaa gag cag agg ggc cgg tgg gag cca tgg gga gtc cgc cta gct cca      192
 Lys Glu Gln Arg Gly Arg Trp Glu Pro Trp Gly Val Arg Leu Ala Pro
      50                  55                  60

 gag aag ctg aca agt acc tgc cgg aaa aac tgc ctc ttt tcc ctc ccg      240
 Glu Lys Leu Thr Ser Thr Cys Arg Lys Asn Cys Leu Phe Ser Leu Pro
  65                  70                  75                  80

 tgc ttg gag cag gca ttg ctg aca gat cac agc tgc tgg gcc caa agg      288
 Cys Leu Glu Gln Ala Leu Leu Thr Asp His Ser Cys Trp Ala Gln Arg
                  85                  90                  95

 tcc ctt tgc acg cgg gac ttc agg aag ttg ctg ctg acc tat ggg agt      336
 Ser Leu Cys Thr Arg Asp Phe Arg Lys Leu Leu Leu Thr Tyr Gly Ser
             100                 105                 110

 tgg tct gga tcc gct tgg tcc aag ctt acc act tgg tct gag cag att      384
 Trp Ser Gly Ser Ala Trp Ser Lys Leu Thr Thr Trp Ser Glu Gln Ile
         115                 120                 125

 ggg gcc ttt gcc ttc cca agc agc acc aac aca ggg cat gtg gac acc      432
 Gly Ala Phe Ala Phe Pro Ser Ser Thr Asn Thr Gly His Val Asp Thr
     130                 135                 140

 tct gaa ggc aga gcc aag agg gcc cca gga agg ggc cga gtc cac acg      480
 Ser Glu Gly Arg Ala Lys Arg Ala Pro Gly Arg Gly Arg Val His Thr
 145                 150                 155                 160

 ttt acc aag cag att gtc aga aag agg att gag agt aaa agt gaa gcc      528
 Phe Thr Lys Gln Ile Val Arg Lys Arg Ile Glu Ser Lys Ser Glu Ala
                 165                 170                 175

 acc tgg aag ctg gag gaa aac aca cca ggc ttt gtg cag cac ggc cca      576
 Thr Trp Lys Leu Glu Glu Asn Thr Pro Gly Phe Val Gln His Gly Pro
             180                 185                 190

 gca ctg atg cag gga gaa ggg gct gtc cga aat aga gac tgc tcc ttc      624
 Ala Leu Met Gln Gly Glu Gly Ala Val Arg Asn Arg Asp Cys Ser Phe
         195                 200                 205

 agc ctg gac cca act gcg aag aag cca cat gga aca gag ctg cag cta      672
 Ser Leu Asp Pro Thr Ala Lys Lys Pro His Gly Thr Glu Leu Gln Leu
     210                 215                 220

 acc tga                                                              678
 Thr 
 225





      <210> 333
      <211> 474
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(474)

      <400> 333
  atg gtc gcg cac gag gtt ggg gtg ctc gcg gcg ctc acg gca ctg cag      48
  Met Val Ala His Glu Val Gly Val Leu Ala Ala Leu Thr Ala Leu Gln
    1               5                  10                  15

 gtt gtc agt ggt gat gga gaa ggg cac ctc tgt ggc gtc cag ggc gcg       96
 Val Val Ser Gly Asp Gly Glu Gly His Leu Cys Gly Val Gln Gly Ala
              20                  25                  30

 ctc cag ccg ttg ctt ctg ggc cag gag caa gtt ggt ctc cgc agc cag      144
 Leu Gln Pro Leu Leu Leu Gly Gln Glu Gln Val Gly Leu Arg Ser Gln
          35                  40                  45

 cgc ctc cat ctc acg ctg cag ctc cga ctt cca gct gtg cgt gtc ctg      192
 Arg Leu His Leu Thr Leu Gln Leu Arg Leu Pro Ala Val Arg Val Leu
      50                  55                  60

 cag tcg ctc gcc cac tgt gcg cgt gga gtc ttg ctg cgt gcg ctg cgc      240
 Gln Ser Leu Ala His Cys Ala Arg Gly Val Leu Leu Arg Ala Leu Arg
  65                  70                  75                  80

 cag cgc ctg ggt ctc tgt ggc cag ctg ctg gct ctc gtg ccg ctg ccg      288
 Gln Arg Leu Gly Leu Cys Gly Gln Leu Leu Ala Leu Val Pro Leu Pro
                  85                  90                  95

 ctc cga ctg gtc gcg gtc ggc gaa ggc ctg gtg gta gcg agc ata gca      336
 Leu Arg Leu Val Ala Val Gly Glu Gly Leu Val Val Ala Ser Ile Ala
             100                 105                 110

 gtt ctg gaa cca ctc ctc cag cag ggc gga ggc agg tcc tgt gct gcg      384
 Val Leu Glu Pro Leu Leu Gln Gln Gly Gly Gly Arg Ser Cys Ala Ala
         115                 120                 125

 gag gct gcc ctc aaa gcc att cag ggc cag gct gcc tgg cgg agg ctg      432
 Glu Ala Ala Leu Lys Ala Ile Gln Gly Gln Ala Ala Trp Arg Arg Leu
     130                 135                 140

 gat ggg cag gaa gcg ccc cag gac aca tcg gag tcc ccc taa              474
 Asp Gly Gln Glu Ala Pro Gln Asp Thr Ser Glu Ser Pro 
 145                 150                 155





      <210> 334
      <211> 1098
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1098)

      <400> 334
  atg tcg ctg tgg aag aaa acc gtc tac cgg agt ctg tgc ctg gcc ctg      48
  Met Ser Leu Trp Lys Lys Thr Val Tyr Arg Ser Leu Cys Leu Ala Leu
    1               5                  10                  15

 gcc ctg ctc gtg gcc gtg acg gtg ttc caa cgc agt ctc acc cct ggt       96
 Ala Leu Leu Val Ala Val Thr Val Phe Gln Arg Ser Leu Thr Pro Gly
              20                  25                  30

 cag ttt ctg cag gag cct ccg cca ccc acc ctg gag cca cag aag gcc      144
 Gln Phe Leu Gln Glu Pro Pro Pro Pro Thr Leu Glu Pro Gln Lys Ala
          35                  40                  45

 cag aag cca aat gga cag ctg gtg aac ccc aac aac ttc tgg aag aac      192
 Gln Lys Pro Asn Gly Gln Leu Val Asn Pro Asn Asn Phe Trp Lys Asn
      50                  55                  60

 ccg aaa gat gtc ctg gag ccg cag ttc cgg cag ttt ctc ttc tac cgc      240
 Pro Lys Asp Val Leu Glu Pro Gln Phe Arg Gln Phe Leu Phe Tyr Arg
  65                  70                  75                  80

 cac tgc cgc tac ttc ccc atg ctg ctg aac cac ccg gag aag tgc agg      288
 His Cys Arg Tyr Phe Pro Met Leu Leu Asn His Pro Glu Lys Cys Arg
                  85                  90                  95

 ggc gat gtc tac ctg ctg gtg gtt gtc aag tcg gtc atc acg cag cac      336
 Gly Asp Val Tyr Leu Leu Val Val Val Lys Ser Val Ile Thr Gln His
             100                 105                 110

 gac cgc cgc gag gcc atc cgc cag acc tgg gcg cga gcg gca gtc cgc      384
 Asp Arg Arg Glu Ala Ile Arg Gln Thr Trp Ala Arg Ala Ala Val Arg
         115                 120                 125

 ggg tgg ggg ccg agc gcc gtg cgc acc ctc ttc ctg ctg ggc acg gcc      432
 Gly Trp Gly Pro Ser Ala Val Arg Thr Leu Phe Leu Leu Gly Thr Ala
     130                 135                 140

 tcc aag cag gag gag cgc acg cac tac cag cag ctg ctg gcc tac gaa      480
 Ser Lys Gln Glu Glu Arg Thr His Tyr Gln Gln Leu Leu Ala Tyr Glu
 145                 150                 155                 160

 gac gcc ctc tac ggc gac atc ctg cag tgg ggc ttt ctc gac acc ttc      528
 Asp Ala Leu Tyr Gly Asp Ile Leu Gln Trp Gly Phe Leu Asp Thr Phe
                 165                 170                 175

 ttc aac ctg acc ctc aag gag atc cac ttc ctc aag tgg ctg gac atc      576
 Phe Asn Leu Thr Leu Lys Glu Ile His Phe Leu Lys Trp Leu Asp Ile
             180                 185                 190

 tac tgc ccc cac gtc ccc ttc att ttc aaa ggc gac gat gac gtc ttc      624
 Tyr Cys Pro His Val Pro Phe Ile Phe Lys Gly Asp Asp Asp Val Phe
         195                 200                 205

 gtc aac ccc acc aac ctg cta gaa ttt ctg gct gac cgg cag cca cag      672
 Val Asn Pro Thr Asn Leu Leu Glu Phe Leu Ala Asp Arg Gln Pro Gln
     210                 215                 220

 gaa aac ctg ttc gtg ggc gat gtc ctg cag cac gct cgg ccc att cgc      720
 Glu Asn Leu Phe Val Gly Asp Val Leu Gln His Ala Arg Pro Ile Arg
 225                 230                 235                 240

 agg aaa gac aac aaa tac tac atc ccg ggg gcc ctg tac ggc aag gcc      768
 Arg Lys Asp Asn Lys Tyr Tyr Ile Pro Gly Ala Leu Tyr Gly Lys Ala
                 245                 250                 255

 agc tat ccg ccg tat gca ggc ggc ggt ggc ttc ctc atg gcc ggc agc      816
 Ser Tyr Pro Pro Tyr Ala Gly Gly Gly Gly Phe Leu Met Ala Gly Ser
             260                 265                 270

 ctg gcc cgg cgc ctg cac cat gcc tgc gac acc ctg gag ctc tac ccg      864
 Leu Ala Arg Arg Leu His His Ala Cys Asp Thr Leu Glu Leu Tyr Pro
         275                 280                 285

 atc gac gac gtc ttt ctg ggc atg tgc ctg gag gtg ctg ggc gtg cag      912
 Ile Asp Asp Val Phe Leu Gly Met Cys Leu Glu Val Leu Gly Val Gln
     290                 295                 300

 ccc acg gcc cac gag ggc ttc aag act ttc ggc atc tcc cgg aac cgc      960
 Pro Thr Ala His Glu Gly Phe Lys Thr Phe Gly Ile Ser Arg Asn Arg
 305                 310                 315                 320

 aac agc cgc atg aac aag gag ccg tgc ttt ttc cgc gcc atg ctc gtg     1008
 Asn Ser Arg Met Asn Lys Glu Pro Cys Phe Phe Arg Ala Met Leu Val
                 325                 330                 335

 gtg cac aag ctg ctg ccc cct gag ctg ctc gcc atg tgg ggg ctg gtg     1056
 Val His Lys Leu Leu Pro Pro Glu Leu Leu Ala Met Trp Gly Leu Val
             340                 345                 350

 cac agc aat ctc acc tgc tcc cgc aag ctc cag gtg ctc tga             1098
 His Ser Asn Leu Thr Cys Ser Arg Lys Leu Gln Val Leu 
         355                 360                 365





      <210> 335
      <211> 267
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(267)

      <400> 335
  atg agc ctg ctg gga gcc tgc aca agc cgg ctc tgc acc ctc tgc ggg      48
  Met Ser Leu Leu Gly Ala Cys Thr Ser Arg Leu Cys Thr Leu Cys Gly
    1               5                  10                  15

 gct cac gca ggt tca gct cct gca gcc ctt ccg ggg cca cag ctg tgg       96
 Ala His Ala Gly Ser Ala Pro Ala Ala Leu Pro Gly Pro Gln Leu Trp
              20                  25                  30

 atc cac agg tcc ctc agc tcc atg gca ctg caa gac acc cgg gag gag      144
 Ile His Arg Ser Leu Ser Ser Met Ala Leu Gln Asp Thr Arg Glu Glu
          35                  40                  45

 ctg ccc aag acg gca gcc cca ctc cag acc ctg tct gat ggg ccg tgc      192
 Leu Pro Lys Thr Ala Ala Pro Leu Gln Thr Leu Ser Asp Gly Pro Cys
      50                  55                  60

 acg tct gca cat tcc aca gaa tgt gac cag ctg tgg agc tca ata caa      240
 Thr Ser Ala His Ser Thr Glu Cys Asp Gln Leu Trp Ser Ser Ile Gln
  65                  70                  75                  80

 aat ggc cct ctg ctg gcc ggg ccc tga                                  267
 Asn Gly Pro Leu Leu Ala Gly Pro 
                  85





      <210> 336
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 336
  atg ctg ctg ggc cca cgc tcc acg tac aca ggc atg cac tcg ctg agg      48
  Met Leu Leu Gly Pro Arg Ser Thr Tyr Thr Gly Met His Ser Leu Arg
    1               5                  10                  15

 agg gca acc ctg gtg ctg ctc ctt atg aca gtc aca cgc agg ttc gaa       96
 Arg Ala Thr Leu Val Leu Leu Leu Met Thr Val Thr Arg Arg Phe Glu
              20                  25                  30

 aag aat gac cgt gga gga gcg gac gag acc aca gaa caa gac ggg atc      144
 Lys Asn Asp Arg Gly Gly Ala Asp Glu Thr Thr Glu Gln Asp Gly Ile
          35                  40                  45

 atc ttc aaa tct gag tgt ttt gag gac ctt ggg gct gaa gaa cgg ctg      192
 Ile Phe Lys Ser Glu Cys Phe Glu Asp Leu Gly Ala Glu Glu Arg Leu
      50                  55                  60

 gct aat cgg tcc caa acc ctg tta tga                                  219
 Ala Asn Arg Ser Gln Thr Leu Leu 
  65                  70





      <210> 337
      <211> 300
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(300)

      <400> 337
  atg cta agc atg cat tta ctg cat tca ttc aac gtg tat tta tgg ggg      48
  Met Leu Ser Met His Leu Leu His Ser Phe Asn Val Tyr Leu Trp Gly
    1               5                  10                  15

 cat tta ctg tat ata ccg ctg tat gct tcg tat ata ccg gtc ctg tcc       96
 His Leu Leu Tyr Ile Pro Leu Tyr Ala Ser Tyr Ile Pro Val Leu Ser
              20                  25                  30

 aac aaa cga atg gat aaa gca cgg aga gga acc aag aat gtg ctc aga      144
 Asn Lys Arg Met Asp Lys Ala Arg Arg Gly Thr Lys Asn Val Leu Arg
          35                  40                  45

 aaa aaa tcc ttc ctc act gaa acc agg act aag gaa agg aga ttc cct      192
 Lys Lys Ser Phe Leu Thr Glu Thr Arg Thr Lys Glu Arg Arg Phe Pro
      50                  55                  60

 tct acc atc cat gcc cat aac cag gca ctg tgt aaa ccg ctt tac ctc      240
 Ser Thr Ile His Ala His Asn Gln Ala Leu Cys Lys Pro Leu Tyr Leu
  65                  70                  75                  80

 att cag tct ttg caa tta tac cac aag ggt ttc gtg aag att caa cga      288
 Ile Gln Ser Leu Gln Leu Tyr His Lys Gly Phe Val Lys Ile Gln Arg
                  85                  90                  95

 gtg cat gcc taa                                                      300
 Val His Ala 






      <210> 338
      <211> 225
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(225)

      <400> 338
  atg agg ctc ttc ctg tcg ctc ccg gtc ctg gtg gtg gtt ctg tcg atc      48
  Met Arg Leu Phe Leu Ser Leu Pro Val Leu Val Val Val Leu Ser Ile
    1               5                  10                  15

 gtc ttg gaa gaa gtc tcc aac ccc ttt gat ggc ctg gag gag tta gga       96
 Val Leu Glu Glu Val Ser Asn Pro Phe Asp Gly Leu Glu Glu Leu Gly
              20                  25                  30

 aag acc ctg gag gac tac act cgg gaa ttc atc aac cgc atc aca cag      144
 Lys Thr Leu Glu Asp Tyr Thr Arg Glu Phe Ile Asn Arg Ile Thr Gln
          35                  40                  45

 agt gaa ctt cct gcc aag atg tgg gat tgg ttt tca gag aca ttt cgg      192
 Ser Glu Leu Pro Ala Lys Met Trp Asp Trp Phe Ser Glu Thr Phe Arg
      50                  55                  60

 aaa gtg aag gag aaa ctc aag act gac tca tga                          225
 Lys Val Lys Glu Lys Leu Lys Thr Asp Ser 
  65                  70





      <210> 339
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 339
  atg gcc agg tgc ctt ggc caa ggt gcc cca ggt gtg tgg gca gtg ctg      48
  Met Ala Arg Cys Leu Gly Gln Gly Ala Pro Gly Val Trp Ala Val Leu
    1               5                  10                  15

 ctg gct gcc att aac cag tgg agt aca gag cat gcc tta aaa atc tgg       96
 Leu Ala Ala Ile Asn Gln Trp Ser Thr Glu His Ala Leu Lys Ile Trp
              20                  25                  30

 ttg cag aag tac atc tac tgg tat gga gaa tgt tct cga tat atc agt      144
 Leu Gln Lys Tyr Ile Tyr Trp Tyr Gly Glu Cys Ser Arg Tyr Ile Ser
          35                  40                  45

 gag aaa agc tgt tgt gtg gcc ctc agc tat cgg aag ctg gag aag aac      192
 Glu Lys Ser Cys Cys Val Ala Leu Ser Tyr Arg Lys Leu Glu Lys Asn
      50                  55                  60

 cca gag aag gag gag gag cac tgg gcc cgg ctt cag agg tac tcc ttg      240
 Pro Glu Lys Glu Glu Glu His Trp Ala Arg Leu Gln Arg Tyr Ser Leu
  65                  70                  75                  80

 tcg ctc cag aga gag aac ttc aag aag tga                              270
 Ser Leu Gln Arg Glu Asn Phe Lys Lys 
                  85





      <210> 340
      <211> 351
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(351)

      <400> 340
  atg agg gag tat gga cgg gcc ctg aaa ctg cgg gtc ctg ccg ctg gtt      48
  Met Arg Glu Tyr Gly Arg Ala Leu Lys Leu Arg Val Leu Pro Leu Val
    1               5                  10                  15

 tgt gtg cac ggc caa gag gca gga gcc ccc tgg cat aca ggg ggc caa       96
 Cys Val His Gly Gln Glu Ala Gly Ala Pro Trp His Thr Gly Gly Gln
              20                  25                  30

 gtg cac gac gtc ctc cag tat gga atc atc gca gaa gag aac aag aac      144
 Val His Asp Val Leu Gln Tyr Gly Ile Ile Ala Glu Glu Asn Lys Asn
          35                  40                  45

 ctg cag ccc cag gga gac gag gac ccc ggg aag ttc aag gag gct gag      192
 Leu Gln Pro Gln Gly Asp Glu Asp Pro Gly Lys Phe Lys Glu Ala Glu
      50                  55                  60

 ctg aag atg cgg aag cag ttt ggg atg cct gag ggc gag aag ctg gtg      240
 Leu Lys Met Arg Lys Gln Phe Gly Met Pro Glu Gly Glu Lys Leu Val
  65                  70                  75                  80

 aat tac tac tcc tgc agc tac tgg aag ggc cgc gtg ccc cgg cag ggc      288
 Asn Tyr Tyr Ser Cys Ser Tyr Trp Lys Gly Arg Val Pro Arg Gln Gly
                  85                  90                  95

 tgg ctg tac ctg acg gtc aac cac ctg tgc ttc tac tcc ttc ctg ctg      336
 Trp Leu Tyr Leu Thr Val Asn His Leu Cys Phe Tyr Ser Phe Leu Leu
             100                 105                 110

 ggg aag gaa agg tga                                                  351
 Gly Lys Glu Arg 
         115





      <210> 341
      <211> 780
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(780)

      <400> 341
  atg gtg ttt gac tcc cca cag gaa gct gca gtg att tca tta cta ttt      48
  Met Val Phe Asp Ser Pro Gln Glu Ala Ala Val Ile Ser Leu Leu Phe
    1               5                  10                  15

 gca cac tgg ttg gga atg tgc tca tcc gct gca ggc att cct ctg gct       96
 Ala His Trp Leu Gly Met Cys Ser Ser Ala Ala Gly Ile Pro Leu Ala
              20                  25                  30

 tca tca agc aca tca atg cag aga aaa gag gag cag caa aga ggg tgc      144
 Ser Ser Ser Thr Ser Met Gln Arg Lys Glu Glu Gln Gln Arg Gly Cys
          35                  40                  45

 att tcc agg ata gcg tgg cct ctc aga cca gag cac cca tct cca tcc      192
 Ile Ser Arg Ile Ala Trp Pro Leu Arg Pro Glu His Pro Ser Pro Ser
      50                  55                  60

 ttg ctg gag aat gtc ccg tca gca gca gga tct ggg ggc aag agg ggc      240
 Leu Leu Glu Asn Val Pro Ser Ala Ala Gly Ser Gly Gly Lys Arg Gly
  65                  70                  75                  80

 acc acc att gaa aga gcc tca tcc aac acc agc ccc acc tgg cac aga      288
 Thr Thr Ile Glu Arg Ala Ser Ser Asn Thr Ser Pro Thr Trp His Arg
                  85                  90                  95

 tac agc ctg aga aca aat tct cat cca aag ggc aag cgt gga ccc gta      336
 Tyr Ser Leu Arg Thr Asn Ser His Pro Lys Gly Lys Arg Gly Pro Val
             100                 105                 110

 cag tcc tct gtg gtc tgc cca cct ctg cat cag tac agc cac ctt atc      384
 Gln Ser Ser Val Val Cys Pro Pro Leu His Gln Tyr Ser His Leu Ile
         115                 120                 125

 cag agg ggc aca gcc aat ctt gga ctc caa gcc tct cct tta ctg ttg      432
 Gln Arg Gly Thr Ala Asn Leu Gly Leu Gln Ala Ser Pro Leu Leu Leu
     130                 135                 140

 act caa gtg act gag ctc aga ctt ccc att ctg aca gcg gca agg agg      480
 Thr Gln Val Thr Glu Leu Arg Leu Pro Ile Leu Thr Ala Ala Arg Arg
 145                 150                 155                 160

 ttc cat gca gat cct gtg gga atg ggc gtt tct gcc ctt att ccc ctg      528
 Phe His Ala Asp Pro Val Gly Met Gly Val Ser Ala Leu Ile Pro Leu
                 165                 170                 175

 tgc att ctt cac gag tgg ttg gat ttc cat gga ctt cat tct gcc aaa      576
 Cys Ile Leu His Glu Trp Leu Asp Phe His Gly Leu His Ser Ala Lys
             180                 185                 190

 gac tca tgt gct gaa tca tat gga act gct gac ctt cca ata aac cag      624
 Asp Ser Cys Ala Glu Ser Tyr Gly Thr Ala Asp Leu Pro Ile Asn Gln
         195                 200                 205

 cat gat ttg cta agg cgt aga gcc agg ctg aga agg aag agg act cag      672
 His Asp Leu Leu Arg Arg Arg Ala Arg Leu Arg Arg Lys Arg Thr Gln
     210                 215                 220

 gcc aga ctg gtg ggt tgg aat cct agc tgt gca gcc gag cag ctt gag      720
 Ala Arg Leu Val Gly Trp Asn Pro Ser Cys Ala Ala Glu Gln Leu Glu
 225                 230                 235                 240

 cac gtt act caa cct cca ccc aat gta cga aaa gca cat agt cca gtt      768
 His Val Thr Gln Pro Pro Pro Asn Val Arg Lys Ala His Ser Pro Val
                 245                 250                 255

 cca agg aca tga                                                      780
 Pro Arg Thr 






      <210> 342
      <211> 1206
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1206)

      <400> 342
  atg gct ttg tct aag gcc aca cag cca gct gga acc atg ctc tcc atc      48
  Met Ala Leu Ser Lys Ala Thr Gln Pro Ala Gly Thr Met Leu Ser Ile
    1               5                  10                  15

 cta ctc aat gcc tcc ttg gcc agc cag gct ttt tct ggc atg gat gcc       96
 Leu Leu Asn Ala Ser Leu Ala Ser Gln Ala Phe Ser Gly Met Asp Ala
              20                  25                  30

 cca ctg ttt gag tgt gaa gtg ttt gaa gct gga gct gct cag tta tca      144
 Pro Leu Phe Glu Cys Glu Val Phe Glu Ala Gly Ala Ala Gln Leu Ser
          35                  40                  45

 gac agt aga aga ggc ctc ctt aca ggc cct ctc cct cgg ctg ctt gcc      192
 Asp Ser Arg Arg Gly Leu Leu Thr Gly Pro Leu Pro Arg Leu Leu Ala
      50                  55                  60

 cag ttc acc gtg cat agc cct gtt gct ccc ctc aat ccc tgc cga ttc      240
 Gln Phe Thr Val His Ser Pro Val Ala Pro Leu Asn Pro Cys Arg Phe
  65                  70                  75                  80

 cca cac cac cgt ttg cct ctg gat tgg ttg ccc act agt cag aac cgt      288
 Pro His His Arg Leu Pro Leu Asp Trp Leu Pro Thr Ser Gln Asn Arg
                  85                  90                  95

 ggg aga gag gaa aca tct gcc atg atg cag gca agg aat gca aag ctc      336
 Gly Arg Glu Glu Thr Ser Ala Met Met Gln Ala Arg Asn Ala Lys Leu
             100                 105                 110

 cca gac atc atg tgg ctc act caa ggt cac cct act atg gcc ctt gcc      384
 Pro Asp Ile Met Trp Leu Thr Gln Gly His Pro Thr Met Ala Leu Ala
         115                 120                 125

 ttt ctg agt gcc tgg ttt gac ctc ttg atc cct cca ggg gag aac gtc      432
 Phe Leu Ser Ala Trp Phe Asp Leu Leu Ile Pro Pro Gly Glu Asn Val
     130                 135                 140

 aca gtc aaa gga ggg gtg caa gag gcc agt ggc aca cag aga gga cta      480
 Thr Val Lys Gly Gly Val Gln Glu Ala Ser Gly Thr Gln Arg Gly Leu
 145                 150                 155                 160

 tca gga tac acc ata cga cac aga agg agc ctg ggc tcc gag tgc ctg      528
 Ser Gly Tyr Thr Ile Arg His Arg Arg Ser Leu Gly Ser Glu Cys Leu
                 165                 170                 175

 agg tcc cac aat aaa tgc cca gaa gag gca gaa ttt aaa ggc tgc tgc      576
 Arg Ser His Asn Lys Cys Pro Glu Glu Ala Glu Phe Lys Gly Cys Cys
             180                 185                 190

 cct ggc tct gca tcc tgt gcc ctt ttt cag gga tct gct agt gat gtg      624
 Pro Gly Ser Ala Ser Cys Ala Leu Phe Gln Gly Ser Ala Ser Asp Val
         195                 200                 205

 cag acc cag agc tcg cat cac cca gtg gtt cag ggc aca gtc ttt gaa      672
 Gln Thr Gln Ser Ser His His Pro Val Val Gln Gly Thr Val Phe Glu
     210                 215                 220

 gcc atg aag cat cag aag gca cga tgg tct tat gta tta aaa gct ggg      720
 Ala Met Lys His Gln Lys Ala Arg Trp Ser Tyr Val Leu Lys Ala Gly
 225                 230                 235                 240

 cgt tgc aca gaa cag caa ctc atc atc agg ttg gag acc ctg gct ggg      768
 Arg Cys Thr Glu Gln Gln Leu Ile Ile Arg Leu Glu Thr Leu Ala Gly
                 245                 250                 255

 ccc ctg gcc cag tgc ccg ccg cct gcc cct ccc gct gag aac agg atg      816
 Pro Leu Ala Gln Cys Pro Pro Pro Ala Pro Pro Ala Glu Asn Arg Met
             260                 265                 270

 tgg gtg tca gga gcc cca gcg gcc ttc cca gct tcc cct gat tgt gta      864
 Trp Val Ser Gly Ala Pro Ala Ala Phe Pro Ala Ser Pro Asp Cys Val
         275                 280                 285

 cag ggc gat aaa ggg gct gat gag agg gag atc tct ggc ggc aca gac      912
 Gln Gly Asp Lys Gly Ala Asp Glu Arg Glu Ile Ser Gly Gly Thr Asp
     290                 295                 300

 aca gcg gcg gcg gag gag gag act gac gct ttg gga agc agc agc cag      960
 Thr Ala Ala Ala Glu Glu Glu Thr Asp Ala Leu Gly Ser Ser Ser Gln
 305                 310                 315                 320

 gcc tgg aac cct ggc cct tgg acc cca aag cct tgg gga tct cca atg     1008
 Ala Trp Asn Pro Gly Pro Trp Thr Pro Lys Pro Trp Gly Ser Pro Met
                 325                 330                 335

 ggc caa tgg gcc acg ctg acc ctg acc ctt agc tct ctg gcc acc cag     1056
 Gly Gln Trp Ala Thr Leu Thr Leu Thr Leu Ser Ser Leu Ala Thr Gln
             340                 345                 350

 aca aca cct ggc ctt gtc aaa gct gtt atc cct tta act cga gaa ctg     1104
 Thr Thr Pro Gly Leu Val Lys Ala Val Ile Pro Leu Thr Arg Glu Leu
         355                 360                 365

 ggc att ttc aga ttg gcc agg aag aaa gag aac agg ggc cag tca gtg     1152
 Gly Ile Phe Arg Leu Ala Arg Lys Lys Glu Asn Arg Gly Gln Ser Val
     370                 375                 380

 tct cac cta tca atg cca ggg gaa aca ggt gca ccg cat gtc cat gtg     1200
 Ser His Leu Ser Met Pro Gly Glu Thr Gly Ala Pro His Val His Val
 385                 390                 395                 400

 aag tga                                                             1206
 Lys 






      <210> 343
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 343
  atg gcg tgc ccc cag ctg ccg cca ctt ctg ctt ttg gtg ctg gtg gtg      48
  Met Ala Cys Pro Gln Leu Pro Pro Leu Leu Leu Leu Val Leu Val Val
    1               5                  10                  15

 ctg ctg aaa gct ggt gtg aat tac aat act ccc ttt aca ggt gac act       96
 Leu Leu Lys Ala Gly Val Asn Tyr Asn Thr Pro Phe Thr Gly Asp Thr
              20                  25                  30

 ggg ccc cgt gag tta cac agg aac ccg agt gtg gtg gtg gtc gtg tgt      144
 Gly Pro Arg Glu Leu His Arg Asn Pro Ser Val Val Val Val Val Cys
          35                  40                  45

 ttg ctg gtg tct ctt ttg ctc atc ggg tct gtg gtc atg gct gtg aga      192
 Leu Leu Val Ser Leu Leu Leu Ile Gly Ser Val Val Met Ala Val Arg
      50                  55                  60

 ttc tgt cac cgg aat gag tcc aag ttt gag aac ctg gac gag gtg tcc      240
 Phe Cys His Arg Asn Glu Ser Lys Phe Glu Asn Leu Asp Glu Val Ser
  65                  70                  75                  80

 atg tgg ttc tgg gag ttg gtg gat tct ggc ttg gcc cct gtg agc ccc      288
 Met Trp Phe Trp Glu Leu Val Asp Ser Gly Leu Ala Pro Val Ser Pro
                  85                  90                  95

 ctt ggt ggt ggt atc atc cgg aga ggc ttc tcg ggt acc cca ttg ctg      336
 Leu Gly Gly Gly Ile Ile Arg Arg Gly Phe Ser Gly Thr Pro Leu Leu
             100                 105                 110

 cca tcg ctg ccg agc cgc ctt gtg ttg cct gga gag gtc gag ccc agt      384
 Pro Ser Leu Pro Ser Arg Leu Val Leu Pro Gly Glu Val Glu Pro Ser
         115                 120                 125

 acc cat gtg gtg ttc acc att gag gct taa                              414
 Thr His Val Val Phe Thr Ile Glu Ala 
     130                 135





      <210> 344
      <211> 774
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(774)

      <400> 344
  atg ctg aca ttg tgg aga cag ctg ttc ttc ttt ctt cag ttc ttc aag      48
  Met Leu Thr Leu Trp Arg Gln Leu Phe Phe Phe Leu Gln Phe Phe Lys
    1               5                  10                  15

 aaa tac ctg acc cct gag aag aga gca gat atg atc atg gtg agc atg       96
 Lys Tyr Leu Thr Pro Glu Lys Arg Ala Asp Met Ile Met Val Ser Met
              20                  25                  30

 gag gcc atg acc aac acc agc agg cgt gac atc tct gca gct tcc aag      144
 Glu Ala Met Thr Asn Thr Ser Arg Arg Asp Ile Ser Ala Ala Ser Lys
          35                  40                  45

 atg tta aag atg atc ctg aag tac acg att cca gag atc ggg aag gtg      192
 Met Leu Lys Met Ile Leu Lys Tyr Thr Ile Pro Glu Ile Gly Lys Val
      50                  55                  60

 ctg gaa atc atc cag tac att cac tac cac atg aac agc att aca gaa      240
 Leu Glu Ile Ile Gln Tyr Ile His Tyr His Met Asn Ser Ile Thr Glu
  65                  70                  75                  80

 acc aca gcc caa aag acc att aag aag atc ctg tat ctg ctg tcc cag      288
 Thr Thr Ala Gln Lys Thr Ile Lys Lys Ile Leu Tyr Leu Leu Ser Gln
                  85                  90                  95

 tac tac act gaa gtt atc ctg aca gcc acc agg gcc atc cat gag ctc      336
 Tyr Tyr Thr Glu Val Ile Leu Thr Ala Thr Arg Ala Ile His Glu Leu
             100                 105                 110

 ctg ctg gaa ccc agt cgg cag atg gag gtg cag tcc ttc ttc tcc tcc      384
 Leu Leu Glu Pro Ser Arg Gln Met Glu Val Gln Ser Phe Phe Ser Ser
         115                 120                 125

 ttg ttc atg gcc ctg ctg ttc cag atc tcc ttt ttg gtg gtt gaa ggg      432
 Leu Phe Met Ala Leu Leu Phe Gln Ile Ser Phe Leu Val Val Glu Gly
     130                 135                 140

 gac gct gaa aca agc cgg gat cag caa cac ata gct gaa tgg atg gac      480
 Asp Ala Glu Thr Ser Arg Asp Gln Gln His Ile Ala Glu Trp Met Asp
 145                 150                 155                 160

 ccc ata agt tct acc atg gag gcc ctg aag acc ttg att caa agt tct      528
 Pro Ile Ser Ser Thr Met Glu Ala Leu Lys Thr Leu Ile Gln Ser Ser
                 165                 170                 175

 gga tat ggg gac tgt gtg tct tct att cag aga cat ggg gtc tgg ggg      576
 Gly Tyr Gly Asp Cys Val Ser Ser Ile Gln Arg His Gly Val Trp Gly
             180                 185                 190

 ctg ctt gtc aat cct gaa aga cac tat ggc gga gtc act ctg ccg gcc      624
 Leu Leu Val Asn Pro Glu Arg His Tyr Gly Gly Val Thr Leu Pro Ala
         195                 200                 205

 agg tcc gtt gtc atc aat aac tgt tgg cac aac cgc ccc ctc ttc agc      672
 Arg Ser Val Val Ile Asn Asn Cys Trp His Asn Arg Pro Leu Phe Ser
     210                 215                 220

 tcc atc atc agg ttc ctc cag gac cca gac ctg caa gaa tca ctt aac      720
 Ser Ile Ile Arg Phe Leu Gln Asp Pro Asp Leu Gln Glu Ser Leu Asn
 225                 230                 235                 240

 ggc cct tgt gtt cct gac aga ggt gac tgg ctc ttg gcg gga ggg ggc      768
 Gly Pro Cys Val Pro Asp Arg Gly Asp Trp Leu Leu Ala Gly Gly Gly
                 245                 250                 255

 agg tga                                                              774
 Arg 






      <210> 345
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 345
  atg tgg ggt cac tca tgc gcc ctc agg gtc cag gcc cca cta gtc ctc      48
  Met Trp Gly His Ser Cys Ala Leu Arg Val Gln Ala Pro Leu Val Leu
    1               5                  10                  15

 ctc caa gtc cca ttt tgg ctg gtg gac acc cag atg acc gca cct cga       96
 Leu Gln Val Pro Phe Trp Leu Val Asp Thr Gln Met Thr Ala Pro Arg
              20                  25                  30

 gca gga gtg ggg atg cca cgt ctg ccc cca gcg ccc ggc cct ctg tcc      144
 Ala Gly Val Gly Met Pro Arg Leu Pro Pro Ala Pro Gly Pro Leu Ser
          35                  40                  45

 acc acg gtc att ccc gga gcc gcc ccg acc ctg tcc gtg ccc aca cca      192
 Thr Thr Val Ile Pro Gly Ala Ala Pro Thr Leu Ser Val Pro Thr Pro
      50                  55                  60

 ggc cag gtg ggc cag ctg ggg gca cag ggc agc tgg aac acc ccc cag      240
 Gly Gln Val Gly Gln Leu Gly Ala Gln Gly Ser Trp Asn Thr Pro Gln
  65                  70                  75                  80

 gtg ccc gtg ctg cca gtc ttc ttg cag cca cct gtg gtc agc atg cct      288
 Val Pro Val Leu Pro Val Phe Leu Gln Pro Pro Val Val Ser Met Pro
                  85                  90                  95

 ggc ccc cgg ctg cgg atc acg tag                                      312
 Gly Pro Arg Leu Arg Ile Thr 
             100





      <210> 346
      <211> 894
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(894)

      <400> 346
  atg ccc ctc cct ctc atc agg ctt gtg ccc agc ggg gtc cgc ctc ctc      48
  Met Pro Leu Pro Leu Ile Arg Leu Val Pro Ser Gly Val Arg Leu Leu
    1               5                  10                  15

 cag aac gct ttc ttc gtg gca cag aga cct tcg gtg tct cac cag aag       96
 Gln Asn Ala Phe Phe Val Ala Gln Arg Pro Ser Val Ser His Gln Lys
              20                  25                  30

 tgc aat ggc cgg att ggg tta atg gaa cct ttg gcg gtg gcc cct ggc      144
 Cys Asn Gly Arg Ile Gly Leu Met Glu Pro Leu Ala Val Ala Pro Gly
          35                  40                  45

 cca ttt ttc aaa cca att ttc cgg cct cac cct ttg aag ata cgg gaa      192
 Pro Phe Phe Lys Pro Ile Phe Arg Pro His Pro Leu Lys Ile Arg Glu
      50                  55                  60

 ttc caa ggc agg ggc cac caa gcc cga gta aat ttt gca gga gaa aaa      240
 Phe Gln Gly Arg Gly His Gln Ala Arg Val Asn Phe Ala Gly Glu Lys
  65                  70                  75                  80

 ctc cac aga gcg tgc tgt ggg cgg ggc cgg ctg tgc agg gag cac cgg      288
 Leu His Arg Ala Cys Cys Gly Arg Gly Arg Leu Cys Arg Glu His Arg
                  85                  90                  95

 gtc ctc gcc ctg ccc ctg tcc tcc aca ctc ccc tac agg gac tgt gcc      336
 Val Leu Ala Leu Pro Leu Ser Ser Thr Leu Pro Tyr Arg Asp Cys Ala
             100                 105                 110

 cct ggc tgc atc ctg cat ttt cct cct ttt gtc cac agg tat gag gta      384
 Pro Gly Cys Ile Leu His Phe Pro Pro Phe Val His Arg Tyr Glu Val
         115                 120                 125

 gat gac att gat gaa gaa ggc aaa gcg aga cac acc gtg agc ttg cgc      432
 Asp Asp Ile Asp Glu Glu Gly Lys Ala Arg His Thr Val Ser Leu Arg
     130                 135                 140

 cgg atc atc ccg ctg acc cgg tgg aag gcc aac ccc gag aca gac ccc      480
 Arg Ile Ile Pro Leu Thr Arg Trp Lys Ala Asn Pro Glu Thr Asp Pro
 145                 150                 155                 160

 gag gcc ttg tta gtc aag gag aaa acc atg ttc tca gga tgc tgt gac      528
 Glu Ala Leu Leu Val Lys Glu Lys Thr Met Phe Ser Gly Cys Cys Asp
                 165                 170                 175

 ctt ggt gac agc acg gcc aac aca gga agc ctc ggc att cac ctg gtc      576
 Leu Gly Asp Ser Thr Ala Asn Thr Gly Ser Leu Gly Ile His Leu Val
             180                 185                 190

 act gag ctc att caa gca aag cga tct cca gta ggg act ttc cct ttt      624
 Thr Glu Leu Ile Gln Ala Lys Arg Ser Pro Val Gly Thr Phe Pro Phe
         195                 200                 205

 gag aac atg tgc aaa ggc ccc aaa ggc tac cgt ccc ctt gcc agc cct      672
 Glu Asn Met Cys Lys Gly Pro Lys Gly Tyr Arg Pro Leu Ala Ser Pro
     210                 215                 220

 ggc agc ctt ggc aag ccc caa gtc agc ggc ttc cct tct gca gcc cca      720
 Gly Ser Leu Gly Lys Pro Gln Val Ser Gly Phe Pro Ser Ala Ala Pro
 225                 230                 235                 240

 gga gaa cca gct ctg aga cag gaa gct cct gcc ctg aac cca cgg ctc      768
 Gly Glu Pro Ala Leu Arg Gln Glu Ala Pro Ala Leu Asn Pro Arg Leu
                 245                 250                 255

 ctg ccc cct cat gct cct ggt gac atg gga cac aag cca cct gag gcc      816
 Leu Pro Pro His Ala Pro Gly Asp Met Gly His Lys Pro Pro Glu Ala
             260                 265                 270

 agg atc cct gcc tgc cac cat ctg ggc tgc cct cgg tcc tct gaa cac      864
 Arg Ile Pro Ala Cys His His Leu Gly Cys Pro Arg Ser Ser Glu His
         275                 280                 285

 aga gtc cct gaa agg cag cag acc ctc tag                              894
 Arg Val Pro Glu Arg Gln Gln Thr Leu 
     290                 295





      <210> 347
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 347
  atg aaa aca cta ttg gcc cgt gca tca aga ttc ctg gct ttg cca cga      48
  Met Lys Thr Leu Leu Ala Arg Ala Ser Arg Phe Leu Ala Leu Pro Arg
    1               5                  10                  15

 act agc ttt aat gcc ctt agt aag tca cac aac ctc ttg ggt ttc aag       96
 Thr Ser Phe Asn Ala Leu Ser Lys Ser His Asn Leu Leu Gly Phe Lys
              20                  25                  30

 gac atc cgc agt aac gtg gaa gcc ttg gcc cag aag acc cag ccc tct      144
 Asp Ile Arg Ser Asn Val Glu Ala Leu Ala Gln Lys Thr Gln Pro Ser
          35                  40                  45

 gtg ttc ccc aag gag tca gtc caa gtt aca cca gtt tgc tat act aaa      192
 Val Phe Pro Lys Glu Ser Val Gln Val Thr Pro Val Cys Tyr Thr Lys
      50                  55                  60

 gga gac agg gaa agt gtg cag aag tgt ccg ctt att ttt aga agc cac      240
 Gly Asp Arg Glu Ser Val Gln Lys Cys Pro Leu Ile Phe Arg Ser His
  65                  70                  75                  80

 tca gcc aca gaa cag gtg tcc ata aga aga gga gtg att gtt cgt gtg      288
 Ser Ala Thr Glu Gln Val Ser Ile Arg Arg Gly Val Ile Val Arg Val
                  85                  90                  95

 gct aag tgg cga gga gag agt cac atc cat gga ggg cct gat gtg cca      336
 Ala Lys Trp Arg Gly Glu Ser His Ile His Gly Gly Pro Asp Val Pro
             100                 105                 110

 ggc ctt gtc cta gac acc tct tat gaa aca tca cct tta atc cac aca      384
 Gly Leu Val Leu Asp Thr Ser Tyr Glu Thr Ser Pro Leu Ile His Thr
         115                 120                 125

 cca gcc ctg aga gtg tat tac att gga gaa gac att gca atg gaa caa      432
 Pro Ala Leu Arg Val Tyr Tyr Ile Gly Glu Asp Ile Ala Met Glu Gln
     130                 135                 140

 gtc act aac cta gca ttt ccc ctg cta tat tcc aac tcc cat agg gtt      480
 Val Thr Asn Leu Ala Phe Pro Leu Leu Tyr Ser Asn Ser His Arg Val
 145                 150                 155                 160

 tca gag cct ggg gaa ctg ggc ttc tgg ggt cca gga gag tca gtg atg      528
 Ser Glu Pro Gly Glu Leu Gly Phe Trp Gly Pro Gly Glu Ser Val Met
                 165                 170                 175

 ccg gca gat gct gtg tca gtg cct tgc acg tgc cat cct gga tct tac      576
 Pro Ala Asp Ala Val Ser Val Pro Cys Thr Cys His Pro Gly Ser Tyr
             180                 185                 190

 gga gtc cag ccc cta gtg ctc aga atc cag ggg tac tca ggc act gga      624
 Gly Val Gln Pro Leu Val Leu Arg Ile Gln Gly Tyr Ser Gly Thr Gly
         195                 200                 205

 cgt tgg atc tca gca tca gca atg agc tgc atc atc tct gac agg aat      672
 Arg Trp Ile Ser Ala Ser Ala Met Ser Cys Ile Ile Ser Asp Arg Asn
     210                 215                 220

 ggg tga                                                              678
 Gly 
 225





      <210> 348
      <211> 471
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(471)

      <400> 348
  atg aag ttc tta gca gtc ctg gta ctc ttg gga gtt tcc atc ttt ctg      48
  Met Lys Phe Leu Ala Val Leu Val Leu Leu Gly Val Ser Ile Phe Leu
    1               5                  10                  15

 gtc tct gcc cag aat ccg aca aca gct gct cca gct gac acg tat cca       96
 Val Ser Ala Gln Asn Pro Thr Thr Ala Ala Pro Ala Asp Thr Tyr Pro
              20                  25                  30

 gct act ggt cct gct gat gat gaa gcc cct gat gct gaa acc act gct      144
 Ala Thr Gly Pro Ala Asp Asp Glu Ala Pro Asp Ala Glu Thr Thr Ala
          35                  40                  45

 gct gca acc act gca acc act gct gct cct acc act gca acc acc gct      192
 Ala Ala Thr Thr Ala Thr Thr Ala Ala Pro Thr Thr Ala Thr Thr Ala
      50                  55                  60

 gct tct acc act gct cgt aaa gac att cca ggt aca gca ctt atg gag      240
 Ala Ser Thr Thr Ala Arg Lys Asp Ile Pro Gly Thr Ala Leu Met Glu
  65                  70                  75                  80

 tcc ctt ctt ttg caa agt act gtg cta tgt tct atg atg ggt tta ggg      288
 Ser Leu Leu Leu Gln Ser Thr Val Leu Cys Ser Met Met Gly Leu Gly
                  85                  90                  95

 gag aag tta caa gta gtg gtg aat gat gac aag aga ggc ttt tgg gta      336
 Glu Lys Leu Gln Val Val Val Asn Asp Asp Lys Arg Gly Phe Trp Val
             100                 105                 110

 tct cca cct ccc tcg cag ccc cct ccc tac tgt gtg ccc tct tcc ccc      384
 Ser Pro Pro Pro Ser Gln Pro Pro Pro Tyr Cys Val Pro Ser Ser Pro
         115                 120                 125

 tcc ctt ctt tct tct tct tta gtg cac atg ttc ctc gat ttg att tac      432
 Ser Leu Leu Ser Ser Ser Leu Val His Met Phe Leu Asp Leu Ile Tyr
     130                 135                 140

 ttc tgt aca ttg tgt ggc tgt gca acg gtt ggt cct tag                  471
 Phe Cys Thr Leu Cys Gly Cys Ala Thr Val Gly Pro 
 145                 150                 155





      <210> 349
      <211> 315
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(315)

      <400> 349
  atg ctt cgt gct ttg att ttc tcc gac aat tta ata atg ttt att gtg      48
  Met Leu Arg Ala Leu Ile Phe Ser Asp Asn Leu Ile Met Phe Ile Val
    1               5                  10                  15

 ctg att gta tat aaa ttc att ggt gca ata aac atg cct gtg ttg tca       96
 Leu Ile Val Tyr Lys Phe Ile Gly Ala Ile Asn Met Pro Val Leu Ser
              20                  25                  30

 gtg cct gag aaa agt gtg gtg ggg atc aag ttc aat ggc gca gct aag      144
 Val Pro Glu Lys Ser Val Val Gly Ile Lys Phe Asn Gly Ala Ala Lys
          35                  40                  45

 ggg gag cag caa gag gaa gca ggg act tgc agt gac tgc cag att ctg      192
 Gly Glu Gln Gln Glu Glu Ala Gly Thr Cys Ser Asp Cys Gln Ile Leu
      50                  55                  60

 gtg gct ccc agt ggg ctg ctc ccc aga cca cct tca cta cag ccc aga      240
 Val Ala Pro Ser Gly Leu Leu Pro Arg Pro Pro Ser Leu Gln Pro Arg
  65                  70                  75                  80

 ctt ttg atg aga att gga cta cag agt ggg tta agc tcc gga tca agt      288
 Leu Leu Met Arg Ile Gly Leu Gln Ser Gly Leu Ser Ser Gly Ser Ser
                  85                  90                  95

 cca gat ggt agc ctc cac tgg ttg tag                                  315
 Pro Asp Gly Ser Leu His Trp Leu 
             100





      <210> 350
      <211> 225
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(225)

      <400> 350
  atg tgg ctg ctg ggg ccg ctg tgc ctg ctg ctg agc agc gcc gcg gaa      48
  Met Trp Leu Leu Gly Pro Leu Cys Leu Leu Leu Ser Ser Ala Ala Glu
    1               5                  10                  15

 gtg ctc act cat gga agc tat ggg gat aaa atc ctt cct gct aat gag       96
 Val Leu Thr His Gly Ser Tyr Gly Asp Lys Ile Leu Pro Ala Asn Glu
              20                  25                  30

 atg aga agg ttg att aac ttt gag ttg ggc tta gtg agt ctg aca cca      144
 Met Arg Arg Leu Ile Asn Phe Glu Leu Gly Leu Val Ser Leu Thr Pro
          35                  40                  45

 gtg gct gcc caa ggg gag tct gct ggt ggg aat tta caa gag cag ctt      192
 Val Ala Ala Gln Gly Glu Ser Ala Gly Gly Asn Leu Gln Glu Gln Leu
      50                  55                  60

 cgg gcc tct cat atg gat gga aag agg atg taa                          225
 Arg Ala Ser His Met Asp Gly Lys Arg Met 
  65                  70





      <210> 351
      <211> 387
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(387)

      <400> 351
  atg gcc cgg gcc ctg tgc cgc ctc ccg cgg cgc ggc ctc tgg ctg ctc      48
  Met Ala Arg Ala Leu Cys Arg Leu Pro Arg Arg Gly Leu Trp Leu Leu
    1               5                  10                  15

 ctg ggc ggg agg ccc cag ggc aca ggg gag gcg gag ggc gcg gac cgg       96
 Leu Gly Gly Arg Pro Gln Gly Thr Gly Glu Ala Glu Gly Ala Asp Arg
              20                  25                  30

 tgt tgc gct tct cgc cgg gga agg gac ggc ttt ggg gac gtc gga gag      144
 Cys Cys Ala Ser Arg Arg Gly Arg Asp Gly Phe Gly Asp Val Gly Glu
          35                  40                  45

 cgg gca ttc tgg aaa gcg tgg ggt gag tca gcc ctg cac act gga gaa      192
 Arg Ala Phe Trp Lys Ala Trp Gly Glu Ser Ala Leu His Thr Gly Glu
      50                  55                  60

 cta gtt ttc aga agg aaa aac agg acg cgg ggt tcc cca gcc ccg cac      240
 Leu Val Phe Arg Arg Lys Asn Arg Thr Arg Gly Ser Pro Ala Pro His
  65                  70                  75                  80

 ctc gtt tct cag gct gtg cgc cgc ggt gac tgc cag cgc agg ctc cct      288
 Leu Val Ser Gln Ala Val Arg Arg Gly Asp Cys Gln Arg Arg Leu Pro
                  85                  90                  95

 tcc cta ggc cgt ccc gcg ttg caa aac ctg cag acg ggc acc ttg cag      336
 Ser Leu Gly Arg Pro Ala Leu Gln Asn Leu Gln Thr Gly Thr Leu Gln
             100                 105                 110

 aag acg cag tgt tcg gga atc aga acc aca gcc ggt ttg tat gga aat      384
 Lys Thr Gln Cys Ser Gly Ile Arg Thr Thr Ala Gly Leu Tyr Gly Asn
         115                 120                 125

 tag                                                                  387
 






      <210> 352
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 352
  atg cct ttc ctg gcc tgt ctc tcc ttc gct gac ctc ctt ttc aag tcc      48
  Met Pro Phe Leu Ala Cys Leu Ser Phe Ala Asp Leu Leu Phe Lys Ser
    1               5                  10                  15

 ctc cca gag aat gct cat acc tta gtc ttt tct ttc ctt ctt cct tca       96
 Leu Pro Glu Asn Ala His Thr Leu Val Phe Ser Phe Leu Leu Pro Ser
              20                  25                  30

 tct ctc tat ttc ttc atc agg aac atc act gtc cat gat ggc agt ctg      144
 Ser Leu Tyr Phe Phe Ile Arg Asn Ile Thr Val His Asp Gly Ser Leu
          35                  40                  45

 ccc ggc aat ctg gcc tgt tcc caa gac tgg cgt ttc act cct cga ttg      192
 Pro Gly Asn Leu Ala Cys Ser Gln Asp Trp Arg Phe Thr Pro Arg Leu
      50                  55                  60

 cac ctg taa                                                          201
 His Leu 
  65





      <210> 353
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 353
  atg gta cgt cca aag aca aag aag aaa ttc ctc cta tca ctg gaa aaa      48
  Met Val Arg Pro Lys Thr Lys Lys Lys Phe Leu Leu Ser Leu Glu Lys
    1               5                  10                  15

 tac agt gag acc aac ttc aca ttg tta cgg gtg tgt ttt ctc ttc ctg       96
 Tyr Ser Glu Thr Asn Phe Thr Leu Leu Arg Val Cys Phe Leu Phe Leu
              20                  25                  30

 ctt cta ctt cat gga ggg ggc aca gga cag agg aag gaa gag gag cca      144
 Leu Leu Leu His Gly Gly Gly Thr Gly Gln Arg Lys Glu Glu Glu Pro
          35                  40                  45

 gcc ttc cta ggc acc agg aag gcc aca ggg caa gca agg ggc tct tca      192
 Ala Phe Leu Gly Thr Arg Lys Ala Thr Gly Gln Ala Arg Gly Ser Ser
      50                  55                  60

 atg ttc cca aac agc cac aga tgg caa att aca ttc cct cag gca cag      240
 Met Phe Pro Asn Ser His Arg Trp Gln Ile Thr Phe Pro Gln Ala Gln
  65                  70                  75                  80

 cgg agg gaa aac tat cca cta aaa gaa acc gaa aga tct ttc aat acc      288
 Arg Arg Glu Asn Tyr Pro Leu Lys Glu Thr Glu Arg Ser Phe Asn Thr
                  85                  90                  95

 aaa caa ggt cga gag ttc cag aag ctt cca ctg gtt tca gaa gcg ttc      336
 Lys Gln Gly Arg Glu Phe Gln Lys Leu Pro Leu Val Ser Glu Ala Phe
             100                 105                 110

 tat tgc caa cat acg ttc agg gtg aat tta aaa gta gga atc tac aca      384
 Tyr Cys Gln His Thr Phe Arg Val Asn Leu Lys Val Gly Ile Tyr Thr
         115                 120                 125

 cgt cta gaa ata aaa tca agg ttg gat taa                              414
 Arg Leu Glu Ile Lys Ser Arg Leu Asp 
     130                 135





      <210> 354
      <211> 657
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(657)

      <400> 354
  atg tgg ctg cag gcc gtt tct ttg caa ctc atg att cat cta act gct      48
  Met Trp Leu Gln Ala Val Ser Leu Gln Leu Met Ile His Leu Thr Ala
    1               5                  10                  15

 cgt ggc aca gat gag atc aaa gcc cag aga aga gct tcc tgc gat cag       96
 Arg Gly Thr Asp Glu Ile Lys Ala Gln Arg Arg Ala Ser Cys Asp Gln
              20                  25                  30

 ctc ccc gct aag ttc cct gcc ctt gga ctc tct aag tgt ctg ctt ctg      144
 Leu Pro Ala Lys Phe Pro Ala Leu Gly Leu Ser Lys Cys Leu Leu Leu
          35                  40                  45

 gaa gag gcc caa gcc aag acc tgg gag aca gac tct cca ggt cat gat      192
 Glu Glu Ala Gln Ala Lys Thr Trp Glu Thr Asp Ser Pro Gly His Asp
      50                  55                  60

 gtg acc aag gtt gcc cct tgc cac tcc cag ctt tat tct cac cag ctc      240
 Val Thr Lys Val Ala Pro Cys His Ser Gln Leu Tyr Ser His Gln Leu
  65                  70                  75                  80

 agc aac ccc agg gaa aag gga gca cca att tcc aat tgt ttc aga aca      288
 Ser Asn Pro Arg Glu Lys Gly Ala Pro Ile Ser Asn Cys Phe Arg Thr
                  85                  90                  95

 agg aaa tcc aag aga cac cca ctc tgc tgc tat ctc ctc ctt cca ccc      336
 Arg Lys Ser Lys Arg His Pro Leu Cys Cys Tyr Leu Leu Leu Pro Pro
             100                 105                 110

 cat cag ctc act tgc ttc cac ctt ccc tac att ccc aac tgg aat gcc      384
 His Gln Leu Thr Cys Phe His Leu Pro Tyr Ile Pro Asn Trp Asn Ala
         115                 120                 125

 cac cct acc atg cac tcg tca cct gca gct tcc cct ttt gga cca ggt      432
 His Pro Thr Met His Ser Ser Pro Ala Ala Ser Pro Phe Gly Pro Gly
     130                 135                 140

 att gag gat aca att tta atc ata ccc ccc agt gga cca gca agc tca      480
 Ile Glu Asp Thr Ile Leu Ile Ile Pro Pro Ser Gly Pro Ala Ser Ser
 145                 150                 155                 160

 aaa aca cgt agt gat gga aat aag cta gct acg ctc aat gcc atc gtc      528
 Lys Thr Arg Ser Asp Gly Asn Lys Leu Ala Thr Leu Asn Ala Ile Val
                 165                 170                 175

 aat gtt act aat gtt gac aaa gaa tct ttc cag aaa cca aaa agg gac      576
 Asn Val Thr Asn Val Asp Lys Glu Ser Phe Gln Lys Pro Lys Arg Asp
             180                 185                 190

 aca gag gaa tca ctg aag cca gct ggt aat gta ggc aca ttg ttc aga      624
 Thr Glu Glu Ser Leu Lys Pro Ala Gly Asn Val Gly Thr Leu Phe Arg
         195                 200                 205

 aac tgt ggc caa gtt cca caa gag aaa aag taa                          657
 Asn Cys Gly Gln Val Pro Gln Glu Lys Lys 
     210                 215





      <210> 355
      <211> 1101
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1101)

      <400> 355
  atg gga cct gcc tgg gtc cag gac ccc ttg aca ggt gct ctc tgg ctg      48
  Met Gly Pro Ala Trp Val Gln Asp Pro Leu Thr Gly Ala Leu Trp Leu
    1               5                  10                  15

 cct gtc ctc tgg gca ctc ttg tcc cag gtc tat tgt ttt cat gac cca       96
 Pro Val Leu Trp Ala Leu Leu Ser Gln Val Tyr Cys Phe His Asp Pro
              20                  25                  30

 cca gga tgg cgc ttc act tcc tca gaa att gtg atc ccc agg aaa gtg      144
 Pro Gly Trp Arg Phe Thr Ser Ser Glu Ile Val Ile Pro Arg Lys Val
          35                  40                  45

 ccc cac agg agg ggt gga gtt gag atg cca gac cag ctc tct tac agc      192
 Pro His Arg Arg Gly Gly Val Glu Met Pro Asp Gln Leu Ser Tyr Ser
      50                  55                  60

 atg cat ttc cgg ggc cga aga cac gtg att cac atg aag ctc aag aag      240
 Met His Phe Arg Gly Arg Arg His Val Ile His Met Lys Leu Lys Lys
  65                  70                  75                  80

 aac atg atg ccc aga cat tta cct gtt ttt act aat aat gac caa ggg      288
 Asn Met Met Pro Arg His Leu Pro Val Phe Thr Asn Asn Asp Gln Gly
                  85                  90                  95

 gcc atg cag gag aac tac cct ttt gtc cca cga gac tgt tac tac gat      336
 Ala Met Gln Glu Asn Tyr Pro Phe Val Pro Arg Asp Cys Tyr Tyr Asp
             100                 105                 110

 tgc tac ctg gaa ggg gtt cct ggg tct gtg gcc aca ttg gac acc tgc      384
 Cys Tyr Leu Glu Gly Val Pro Gly Ser Val Ala Thr Leu Asp Thr Cys
         115                 120                 125

 cgt gga ggt ctg cgt ggc atg ctg cag gtg gat gac ctg act tat gaa      432
 Arg Gly Gly Leu Arg Gly Met Leu Gln Val Asp Asp Leu Thr Tyr Glu
     130                 135                 140

 atc aaa ccc ctg gag gct ttt tcc aaa ttt gag tat gta gta tct ctg      480
 Ile Lys Pro Leu Glu Ala Phe Ser Lys Phe Glu Tyr Val Val Ser Leu
 145                 150                 155                 160

 ctt gtg tca gaa gaa aga cca gga gag gtc agt aga tgt aag act gaa      528
 Leu Val Ser Glu Glu Arg Pro Gly Glu Val Ser Arg Cys Lys Thr Glu
                 165                 170                 175

 ggg gaa gag ata gat caa gaa tct gaa aag gag agt ttg gtt cgt gga      576
 Gly Glu Glu Ile Asp Gln Glu Ser Glu Lys Glu Ser Leu Val Arg Gly
             180                 185                 190

 aat att atg aat ggt ttt cac aaa ttc cac atg ata cct cag ttg ttt      624
 Asn Ile Met Asn Gly Phe His Lys Phe His Met Ile Pro Gln Leu Phe
         195                 200                 205

 tta cat caa att gac ttg gaa aca gtg agt gtt atg cca gct ttg acg      672
 Leu His Gln Ile Asp Leu Glu Thr Val Ser Val Met Pro Ala Leu Thr
     210                 215                 220

 gaa tat gca acc cca act ggg gag caa tct cct cgt tgt gga gac aat      720
 Glu Tyr Ala Thr Pro Thr Gly Glu Gln Ser Pro Arg Cys Gly Asp Asn
 225                 230                 235                 240

 atc aaa aat cag agg gaa gaa tgt gac tgt ggc tcc ctt aaa gat tgt      768
 Ile Lys Asn Gln Arg Glu Glu Cys Asp Cys Gly Ser Leu Lys Asp Cys
                 245                 250                 255

 gcc agt gat aga tgt tgt gag acc tct tgt acc ctt tct ctt ggc agt      816
 Ala Ser Asp Arg Cys Cys Glu Thr Ser Cys Thr Leu Ser Leu Gly Ser
             260                 265                 270

 gtt tgc aat aca gga ctt tgc tgc cat aag tgt aaa tat gct gcc cct      864
 Val Cys Asn Thr Gly Leu Cys Cys His Lys Cys Lys Tyr Ala Ala Pro
         275                 280                 285

 gga gtg gtt tgc aga gac ttg ggt ggt ata tgt gat cta cca aaa tac      912
 Gly Val Val Cys Arg Asp Leu Gly Gly Ile Cys Asp Leu Pro Lys Tyr
     290                 295                 300

 tgt gat ggg aaa aag gaa gag tgt cca aat gac atc tac atc cag gat      960
 Cys Asp Gly Lys Lys Glu Glu Cys Pro Asn Asp Ile Tyr Ile Gln Asp
 305                 310                 315                 320

 gga acc cca tgt tca gca gta tct gtt tgt ata aga gga aac tgc agt     1008
 Gly Thr Pro Cys Ser Ala Val Ser Val Cys Ile Arg Gly Asn Cys Ser
                 325                 330                 335

 gac cgt gat atg cag tgt caa gcc ctt ttt ggc tac caa gtg aaa gac     1056
 Asp Arg Asp Met Gln Cys Gln Ala Leu Phe Gly Tyr Gln Val Lys Asp
             340                 345                 350

 ggt tcc cca gcg tgc tat caa aaa ttg aat agg att ggt aac tga         1101
 Gly Ser Pro Ala Cys Tyr Gln Lys Leu Asn Arg Ile Gly Asn 
         355                 360                 365





      <210> 356
      <211> 561
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(561)

      <400> 356
  atg gtg gct gtc cgt tgt gcg ttt gtg ttc ttg ggt gtg ttt gtg cgg      48
  Met Val Ala Val Arg Cys Ala Phe Val Phe Leu Gly Val Phe Val Arg
    1               5                  10                  15

 tcg gtc gcg cta cct cac cct gag gga gag ctg cac cga ggg atg cac       96
 Ser Val Ala Leu Pro His Pro Glu Gly Glu Leu His Arg Gly Met His
              20                  25                  30

 agg gcc ctg ctg tca gct gca gac cgg ggc cct gat cag ccc aga gtc      144
 Arg Ala Leu Leu Ser Ala Ala Asp Arg Gly Pro Asp Gln Pro Arg Val
          35                  40                  45

 aga aaa gac ttt cag gct ctg gag cct tca gga gga ggt aag cag agg      192
 Arg Lys Asp Phe Gln Ala Leu Glu Pro Ser Gly Gly Gly Lys Gln Arg
      50                  55                  60

 aga tca gtg cct gtt tct gac ccc agg agg gcc ttg ttg ggc tcc aac      240
 Arg Ser Val Pro Val Ser Asp Pro Arg Arg Ala Leu Leu Gly Ser Asn
  65                  70                  75                  80

 cta gag cct tcc ggc ttc agg tcc caa gag aag tcc ccc cct aac tgt      288
 Leu Glu Pro Ser Gly Phe Arg Ser Gln Glu Lys Ser Pro Pro Asn Cys
                  85                  90                  95

 gac ccc cct aac tgt gat cag ggg tct gcc att gcc cgc ttt tct ctg      336
 Asp Pro Pro Asn Cys Asp Gln Gly Ser Ala Ile Ala Arg Phe Ser Leu
             100                 105                 110

 cct gat ctg ggg act cag gag agg cca cgg cag cca cag cct agg ggt      384
 Pro Asp Leu Gly Thr Gln Glu Arg Pro Arg Gln Pro Gln Pro Arg Gly
         115                 120                 125

 ggt tca gtc cct ggc cca cag tct ggt cag ttg agt cct tct ggg aac      432
 Gly Ser Val Pro Gly Pro Gln Ser Gly Gln Leu Ser Pro Ser Gly Asn
     130                 135                 140

 cgg ggc tat gaa aac ttt cgt ctt tgg gga ccg gta ccc atg aag gaa      480
 Arg Gly Tyr Glu Asn Phe Arg Leu Trp Gly Pro Val Pro Met Lys Glu
 145                 150                 155                 160

 aac ttt cct gag ggg gtg agg acc aaa gaa tca aga tcc ttt tca ggc      528
 Asn Phe Pro Glu Gly Val Arg Thr Lys Glu Ser Arg Ser Phe Ser Gly
                 165                 170                 175

 ctg ata gcc aag atg atg aga act ttt aga taa                          561
 Leu Ile Ala Lys Met Met Arg Thr Phe Arg 
             180                 185





      <210> 357
      <211> 261
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(261)

      <400> 357
  atg aag gta tct tta gtg acc tta gca agg gta gtc ttg ttg ttc atg      48
  Met Lys Val Ser Leu Val Thr Leu Ala Arg Val Val Leu Leu Phe Met
    1               5                  10                  15

 gtg gac aat gga gca gat gac tgg aga ata gcc atg act tat gag cgt       96
 Val Asp Asn Gly Ala Asp Asp Trp Arg Ile Ala Met Thr Tyr Glu Arg
              20                  25                  30

 att ttc ttc atc tgc ttg gaa ata ctg gtg tgt gct att cat ccc ata      144
 Ile Phe Phe Ile Cys Leu Glu Ile Leu Val Cys Ala Ile His Pro Ile
          35                  40                  45

 cct ggg aat tat aca ttc aca tgg acg gcc cgg ctt gcc ttc tcc tat      192
 Pro Gly Asn Tyr Thr Phe Thr Trp Thr Ala Arg Leu Ala Phe Ser Tyr
      50                  55                  60

 gcc cca tcc aca acc acc gct gat tat ctc att atg gat aat tgc cgc      240
 Ala Pro Ser Thr Thr Thr Ala Asp Tyr Leu Ile Met Asp Asn Cys Arg
  65                  70                  75                  80

 atg gac tgt ccg agc ttg tga                                          261
 Met Asp Cys Pro Ser Leu 
                  85





      <210> 358
      <211> 1338
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1338)

      <400> 358
  atg ctg ttc gtc cag gcc ctg ctc tcg ggg ctc ttc tcc acg cct ctc      48
  Met Leu Phe Val Gln Ala Leu Leu Ser Gly Leu Phe Ser Thr Pro Leu
    1               5                  10                  15

 aac cca ctg cta ggc agt gcc gtc ttc atc atg tcc tac gct cgg ccc       96
 Asn Pro Leu Leu Gly Ser Ala Val Phe Ile Met Ser Tyr Ala Arg Pro
              20                  25                  30

 ctc aag ttc tgg gag cgc gac tac aat ctc ctc atc tgc ctg cat aac      144
 Leu Lys Phe Trp Glu Arg Asp Tyr Asn Leu Leu Ile Cys Leu His Asn
          35                  40                  45

 ggg gct gtc ctg gat ggc gtt gac ctt gtg gca cag gga gag cat gag      192
 Gly Ala Val Leu Asp Gly Val Asp Leu Val Ala Gln Gly Glu His Glu
      50                  55                  60

 cag gtg cac cct ctc ttc acc ttc ttg gcc aac cgc ctt gtt gca ctc      240
 Gln Val His Pro Leu Phe Thr Phe Leu Ala Asn Arg Leu Val Ala Leu
  65                  70                  75                  80

 tct ctg aac agc act aaa cgt gtg gat cat tcc aac acc cgc ctg gtc      288
 Ser Leu Asn Ser Thr Lys Arg Val Asp His Ser Asn Thr Arg Leu Val
                  85                  90                  95

 aca cag ctg gac agg aac cct gca cac act gtg tgg gga cct ggt gct      336
 Thr Gln Leu Asp Arg Asn Pro Ala His Thr Val Trp Gly Pro Gly Ala
             100                 105                 110

 ggg ccg ctg ggc aac tat ggc cct ggt gac tgc ttc gtc ctg gcc tct      384
 Gly Pro Leu Gly Asn Tyr Gly Pro Gly Asp Cys Phe Val Leu Ala Ser
         115                 120                 125

 gac tac ctc aac gcc ctg gtg cac ctc atc gag gtt ggc aat ggc ctc      432
 Asp Tyr Leu Asn Ala Leu Val His Leu Ile Glu Val Gly Asn Gly Leu
     130                 135                 140

 gtc acc ttc cag ctg cgt ggc ctt gag ttc cgg ggt gag ccg cag gac      480
 Val Thr Phe Gln Leu Arg Gly Leu Glu Phe Arg Gly Glu Pro Gln Asp
 145                 150                 155                 160

 cag gct cgg cgc tgg ctg gct tgg gag gta aca gcc agc aag tac gtg      528
 Gln Ala Arg Arg Trp Leu Ala Trp Glu Val Thr Ala Ser Lys Tyr Val
                 165                 170                 175

 ctg gag ggc tat agc att agt gac aat aat gct gcc tcc atg ctg cag      576
 Leu Glu Gly Tyr Ser Ile Ser Asp Asn Asn Ala Ala Ser Met Leu Gln
             180                 185                 190

 gtt ttc gac ctc cgc aag atc ctc atc acc tac tat gtc aag agc atc      624
 Val Phe Asp Leu Arg Lys Ile Leu Ile Thr Tyr Tyr Val Lys Ser Ile
         195                 200                 205

 atc tac tac gtg agc cgc tca cca aag ctg gag gtg tgg ctc agc cat      672
 Ile Tyr Tyr Val Ser Arg Ser Pro Lys Leu Glu Val Trp Leu Ser His
     210                 215                 220

 gag ggc atc acg gca gcc ctg agg cct gtg cgg gtg ccg gct atg ccg      720
 Glu Gly Ile Thr Ala Ala Leu Arg Pro Val Arg Val Pro Ala Met Pro
 225                 230                 235                 240

 acc tcg gat ccc acc ttc tcg ctg agt gtg gat gag gac tat gac ctc      768
 Thr Ser Asp Pro Thr Phe Ser Leu Ser Val Asp Glu Asp Tyr Asp Leu
                 245                 250                 255

 cgc ctg tct ggc ctc tcg ctg ccc tcc ttt tgt gct gtg cac ctc gag      816
 Arg Leu Ser Gly Leu Ser Leu Pro Ser Phe Cys Ala Val His Leu Glu
             260                 265                 270

 tgg atc cag tac tgc gcc tcc cag cgc agc ctg gag ccc ttc ctc tac      864
 Trp Ile Gln Tyr Cys Ala Ser Gln Arg Ser Leu Glu Pro Phe Leu Tyr
         275                 280                 285

 ggc ctg cac gcc ctg ttc aag ggg gat ttt cgc atc acc tcc cca cgt      912
 Gly Leu His Ala Leu Phe Lys Gly Asp Phe Arg Ile Thr Ser Pro Arg
     290                 295                 300

 gac gag tgg gtc ttt gcc gac atg gac ctg ctt cac cgc gtt gtg gcg      960
 Asp Glu Trp Val Phe Ala Asp Met Asp Leu Leu His Arg Val Val Ala
 305                 310                 315                 320

 cct ggg gtt cgc atg gcc ctc aag ctt cac cag gac cac ttc acg tcc     1008
 Pro Gly Val Arg Met Ala Leu Lys Leu His Gln Asp His Phe Thr Ser
                 325                 330                 335

 cca gat gaa tat gag gag cca gca gcc cta tac gat gcc att gcg gcc     1056
 Pro Asp Glu Tyr Glu Glu Pro Ala Ala Leu Tyr Asp Ala Ile Ala Ala
             340                 345                 350

 aac gag gag cgg ctg gtc atc tca cat gag ggt gac cag cat ggc gca     1104
 Asn Glu Glu Arg Leu Val Ile Ser His Glu Gly Asp Gln His Gly Ala
         355                 360                 365

 gcg cca tcc tca gca aca cgc cct ccc tgc tgg ctg cgc cat gtc ctg     1152
 Ala Pro Ser Ser Ala Thr Arg Pro Pro Cys Trp Leu Arg His Val Leu
     370                 375                 380

 gat gat gcc tcc gac gag tac aag atc atc atg ctc aac cgg cgc cac     1200
 Asp Asp Ala Ser Asp Glu Tyr Lys Ile Ile Met Leu Asn Arg Arg His
 385                 390                 395                 400

 ctc agc ttc cga gtc atc aag gtg aac cgg gag tgc gtg cgc ggc ctg     1248
 Leu Ser Phe Arg Val Ile Lys Val Asn Arg Glu Cys Val Arg Gly Leu
                 405                 410                 415

 tgg cag tca gtc agt gag ctg gtg ttc ctg cgc aac cgc aac ccc gag     1296
 Trp Gln Ser Val Ser Glu Leu Val Phe Leu Arg Asn Arg Asn Pro Glu
             420                 425                 430

 cgt ggc agc atc cag aac gcc aag cag gcg ttc gca aca tga             1338
 Arg Gly Ser Ile Gln Asn Ala Lys Gln Ala Phe Ala Thr 
         435                 440                 445





      <210> 359
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 359
  atg gcc tgc tac ctc tta gtg gca aac atc ttg ctg gtc aac ctc ctc      48
  Met Ala Cys Tyr Leu Leu Val Ala Asn Ile Leu Leu Val Asn Leu Leu
    1               5                  10                  15

 att gct gtc ttt aac aat aca ttt ttt gaa gta aaa tcg ata tcc aac       96
 Ile Ala Val Phe Asn Asn Thr Phe Phe Glu Val Lys Ser Ile Ser Asn
              20                  25                  30

 caa gtc tgg aag ttt cag agg tat cag ctc atc atg act ttc cat gaa      144
 Gln Val Trp Lys Phe Gln Arg Tyr Gln Leu Ile Met Thr Phe His Glu
          35                  40                  45

 agg cca gtt ctg ccc cca cca ctg atc atc ttc agc cac atg acc atg      192
 Arg Pro Val Leu Pro Pro Pro Leu Ile Ile Phe Ser His Met Thr Met
      50                  55                  60

 ata ttc cag cac ctg tgc tgc cga tgg agg aaa cac gag agc gac ccg      240
 Ile Phe Gln His Leu Cys Cys Arg Trp Arg Lys His Glu Ser Asp Pro
  65                  70                  75                  80

 gat gaa agg gac tac ggc ctg aga act cta gcc aat gtg gag gag cat      288
 Asp Glu Arg Asp Tyr Gly Leu Arg Thr Leu Ala Asn Val Glu Glu His
                  85                  90                  95

 ggg ata caa aat cag ggg cag cgg gat gct cta atg aat gat agc ctg      336
 Gly Ile Gln Asn Gln Gly Gln Arg Asp Ala Leu Met Asn Asp Ser Leu
             100                 105                 110

 cag tgg ata aca tgc tga                                              354
 Gln Trp Ile Thr Cys 
         115





      <210> 360
      <211> 1221
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1221)

      <400> 360
  atg ggc ctg gca cag gaa ttg gac tgg tca ttt gca aag gtt gct tct      48
  Met Gly Leu Ala Gln Glu Leu Asp Trp Ser Phe Ala Lys Val Ala Ser
    1               5                  10                  15

 tcc tgt tgg aaa aca cag gct tcc tgg tgc atc tca ttt tta aag ctc       96
 Ser Cys Trp Lys Thr Gln Ala Ser Trp Cys Ile Ser Phe Leu Lys Leu
              20                  25                  30

 aca cca ggc tgg ctg ggg cga ggc ggt gtg ctg ctt ctg gcc cca gcc      144
 Thr Pro Gly Trp Leu Gly Arg Gly Gly Val Leu Leu Leu Ala Pro Ala
          35                  40                  45

 cag tgg ctg ccc act gct atc acc ctg tct ctg gcc aca gcc gac ttc      192
 Gln Trp Leu Pro Thr Ala Ile Thr Leu Ser Leu Ala Thr Ala Asp Phe
      50                  55                  60

 tcc atg gct gtc agc atg gcc act ggg gtt cat ggc aag tgc ctg agg      240
 Ser Met Ala Val Ser Met Ala Thr Gly Val His Gly Lys Cys Leu Arg
  65                  70                  75                  80

 tca cca ttt tca aat gaa tgt ggt gtg cag gtg ctc tgt ctg gat gct      288
 Ser Pro Phe Ser Asn Glu Cys Gly Val Gln Val Leu Cys Leu Asp Ala
                  85                  90                  95

 gag ctt gga acc cca ccc tgt agg cca aat tca ttc atg cta gta aga      336
 Glu Leu Gly Thr Pro Pro Cys Arg Pro Asn Ser Phe Met Leu Val Arg
             100                 105                 110

 gag agc aaa act ttg tgg gaa gga att caa ccg gat gca caa cct gat      384
 Glu Ser Lys Thr Leu Trp Glu Gly Ile Gln Pro Asp Ala Gln Pro Asp
         115                 120                 125

 ggg cca cat gca cct gca ctc aga cag caa acc ctt caa gtg cct cta      432
 Gly Pro His Ala Pro Ala Leu Arg Gln Gln Thr Leu Gln Val Pro Leu
     130                 135                 140

 ttg ccc aag caa att cac cct gaa ggg gaa cct gac acg cca cat gaa      480
 Leu Pro Lys Gln Ile His Pro Glu Gly Glu Pro Asp Thr Pro His Glu
 145                 150                 155                 160

 agt caa gca tgg agt cat gga gcg ggg cct tca ttc cca agt gtc ccg      528
 Ser Gln Ala Trp Ser His Gly Ala Gly Pro Ser Phe Pro Ser Val Pro
                 165                 170                 175

 ccc atc cct gga ggc ctg act att ggc tca tca aag gtc aaa gcc tta      576
 Pro Ile Pro Gly Gly Leu Thr Ile Gly Ser Ser Lys Val Lys Ala Leu
             180                 185                 190

 aag aca gga tca aat gaa act gcc atg ctg aaa agc cca tcc cta cag      624
 Lys Thr Gly Ser Asn Glu Thr Ala Met Leu Lys Ser Pro Ser Leu Gln
         195                 200                 205

 ccc tgc aaa ctg aag gca aaa cat ttc ctc agg tgc atg aat tct tac      672
 Pro Cys Lys Leu Lys Ala Lys His Phe Leu Arg Cys Met Asn Ser Tyr
     210                 215                 220

 tct gct ctt gca ggt ctg gga agg ggg aga atc gcc ctg gca cag aca      720
 Ser Ala Leu Ala Gly Leu Gly Arg Gly Arg Ile Ala Leu Ala Gln Thr
 225                 230                 235                 240

 gcc ggt gtc ctg agg agt ctg gag cag gag gag ccc ttt gac ctc tct      768
 Ala Gly Val Leu Arg Ser Leu Glu Gln Glu Glu Pro Phe Asp Leu Ser
                 245                 250                 255

 cag aag cgc cgg gcc aag gtg ccg gtg ttc cag tca gac ggg gag agt      816
 Gln Lys Arg Arg Ala Lys Val Pro Val Phe Gln Ser Asp Gly Glu Ser
             260                 265                 270

 gcc cag ggc agc cac tgc cac gag gag gaa gag gag gat aac tgc tac      864
 Ala Gln Gly Ser His Cys His Glu Glu Glu Glu Glu Asp Asn Cys Tyr
         275                 280                 285

 gag gtg gag ccc tac agc cct ggc ctg gcc ccc cag agc cag cag ctc      912
 Glu Val Glu Pro Tyr Ser Pro Gly Leu Ala Pro Gln Ser Gln Gln Leu
     290                 295                 300

 tgc aca ccc gag gat ctg tcc acc aag tcg gag cac gcc ccc gag gtg      960
 Cys Thr Pro Glu Asp Leu Ser Thr Lys Ser Glu His Ala Pro Glu Val
 305                 310                 315                 320

 ctg gag gaa gcc tgc aag gag gag aag gag gat gca tcc aag gga gaa     1008
 Leu Glu Glu Ala Cys Lys Glu Glu Lys Glu Asp Ala Ser Lys Gly Glu
                 325                 330                 335

 tgg gag aag agg agc aag ggt gac ctt ggg gca gag ggc ggc cag gag     1056
 Trp Glu Lys Arg Ser Lys Gly Asp Leu Gly Ala Glu Gly Gly Gln Glu
             340                 345                 350

 aga gac tgt gcc ggc aga gat gag tgt ctc agt ctc agg gct ttt cag     1104
 Arg Asp Cys Ala Gly Arg Asp Glu Cys Leu Ser Leu Arg Ala Phe Gln
         355                 360                 365

 agt acc cgg cgg ggc ccc tct ttt tct gat tac tta tac ttc aag cac     1152
 Ser Thr Arg Arg Gly Pro Ser Phe Ser Asp Tyr Leu Tyr Phe Lys His
     370                 375                 380

 aga gat gag agt ttg aaa gaa tta ctg gag agg aaa atg gaa aaa caa     1200
 Arg Asp Glu Ser Leu Lys Glu Leu Leu Glu Arg Lys Met Glu Lys Gln
 385                 390                 395                 400

 gca gtg ctt tta ggt atc taa                                         1221
 Ala Val Leu Leu Gly Ile 
                 405





      <210> 361
      <211> 1164
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1164)

      <400> 361
  atg cct gct gta ctc agt gca atc ccc aat aca tgg ttg gtg ctt agc      48
  Met Pro Ala Val Leu Ser Ala Ile Pro Asn Thr Trp Leu Val Leu Ser
    1               5                  10                  15

 atc tgc atc ccc agc cac tca gtc cct ggc ccg gga tct tcc aag gca       96
 Ile Cys Ile Pro Ser His Ser Val Pro Gly Pro Gly Ser Ser Lys Ala
              20                  25                  30

 gcc agc ccc ttt cct cca gcc ctg ctg gcc ccc tgc cga tcc acc agt      144
 Ala Ser Pro Phe Pro Pro Ala Leu Leu Ala Pro Cys Arg Ser Thr Ser
          35                  40                  45

 ggg cac cgc cac cta tct cca tcc ctg gca cgg acc acc aaa cct ctt      192
 Gly His Arg His Leu Ser Pro Ser Leu Ala Arg Thr Thr Lys Pro Leu
      50                  55                  60

 tct agc act aag ggc acc cgc agc agc cag ccc tat atg gct ccc atc      240
 Ser Ser Thr Lys Gly Thr Arg Ser Ser Gln Pro Tyr Met Ala Pro Ile
  65                  70                  75                  80

 atc atc ctg tct gca gga agc ccc gcc tta aat cac ctg tac atg tgc      288
 Ile Ile Leu Ser Ala Gly Ser Pro Ala Leu Asn His Leu Tyr Met Cys
                  85                  90                  95

 att gct ggg tgc cag cag atg att cat gaa act caa cag aca gat gcc      336
 Ile Ala Gly Cys Gln Gln Met Ile His Glu Thr Gln Gln Thr Asp Ala
             100                 105                 110

 ctg gtg ggc aca gga aac cga agg att gag aga cat ggt gga atc aga      384
 Leu Val Gly Thr Gly Asn Arg Arg Ile Glu Arg His Gly Gly Ile Arg
         115                 120                 125

 tgt aag aat cag agg gcc tgg gct gtt gac tct ggg agc aat tat gac      432
 Cys Lys Asn Gln Arg Ala Trp Ala Val Asp Ser Gly Ser Asn Tyr Asp
     130                 135                 140

 cag ggc cat gag gtt caa cag att cct cgc ctt gga gaa ata aag gcg      480
 Gln Gly His Glu Val Gln Gln Ile Pro Arg Leu Gly Glu Ile Lys Ala
 145                 150                 155                 160

 tgg ttc tgg cac atc gac atc act ttt tca aaa tcc aga ttc tcg gac      528
 Trp Phe Trp His Ile Asp Ile Thr Phe Ser Lys Ser Arg Phe Ser Asp
                 165                 170                 175

 tcc ctc cag acc tac tgg atc aga ccc tct aag ggt gga gct caa ccg      576
 Ser Leu Gln Thr Tyr Trp Ile Arg Pro Ser Lys Gly Gly Ala Gln Pro
             180                 185                 190

 tct gtg ctt caa gga gca ctg cag cgg cca tcc ctg tgt gtg gct agt      624
 Ser Val Leu Gln Gly Ala Leu Gln Arg Pro Ser Leu Cys Val Ala Ser
         195                 200                 205

 ggg gaa ttt gtg gga agg ggt ctc cac aac tgg ggc ttg ttg agg gac      672
 Gly Glu Phe Val Gly Arg Gly Leu His Asn Trp Gly Leu Leu Arg Asp
     210                 215                 220

 tcc cac cca atg aca att tgg cac agc tct gag ctg gag ctc ccg tgc      720
 Ser His Pro Met Thr Ile Trp His Ser Ser Glu Leu Glu Leu Pro Cys
 225                 230                 235                 240

 atc ttc agc cag gaa gag gaa gag gga ggc acc aca cca cct agt gcc      768
 Ile Phe Ser Gln Glu Glu Glu Glu Gly Gly Thr Thr Pro Pro Ser Ala
                 245                 250                 255

 cag aac atc ggc att gaa tgg cgc cat aac aaa aga ctc tcc cca ggg      816
 Gln Asn Ile Gly Ile Glu Trp Arg His Asn Lys Arg Leu Ser Pro Gly
             260                 265                 270

 tct aat cat aag atg atc aaa cac ttt cat tca aaa tgc agg act gaa      864
 Ser Asn His Lys Met Ile Lys His Phe His Ser Lys Cys Arg Thr Glu
         275                 280                 285

 act gtg atg act gaa gag gag gaa tgg aag ccc atg gac cca tcc aag      912
 Thr Val Met Thr Glu Glu Glu Glu Trp Lys Pro Met Asp Pro Ser Lys
     290                 295                 300

 atg aga tgc agc ttc ttc cag aat ggc aag gag tct gag aaa gag aag      960
 Met Arg Cys Ser Phe Phe Gln Asn Gly Lys Glu Ser Glu Lys Glu Lys
 305                 310                 315                 320

 gtc ccc aca agg tct ctt ctg gct caa gtg att att ccg cta gta aat     1008
 Val Pro Thr Arg Ser Leu Leu Ala Gln Val Ile Ile Pro Leu Val Asn
                 325                 330                 335

 tac agg tgt ttc ctg cag cag ttg ctc ttt cgg gca ctt tca tgc tac     1056
 Tyr Arg Cys Phe Leu Gln Gln Leu Leu Phe Arg Ala Leu Ser Cys Tyr
             340                 345                 350

 cag cgt gtt cat tgt aac cag att ttc cct gca gag agg cat ggg cac     1104
 Gln Arg Val His Cys Asn Gln Ile Phe Pro Ala Glu Arg His Gly His
         355                 360                 365

 tat ggt ttg agc acc ttt cca ggg atg gct ctc ctg gga cag ctg tgg     1152
 Tyr Gly Leu Ser Thr Phe Pro Gly Met Ala Leu Leu Gly Gln Leu Trp
     370                 375                 380

 gag aaa gga tga                                                     1164
 Glu Lys Gly 
 385





      <210> 362
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 362
  atg tca ggt ttt gaa gtg ttc gca ttt ttt ttc tac tgt atc ttt gcc      48
  Met Ser Gly Phe Glu Val Phe Ala Phe Phe Phe Tyr Cys Ile Phe Ala
    1               5                  10                  15

 tcc ttg tcc atc tat ggc tat agg aag ctc atc ctg gga gtg gag gaa       96
 Ser Leu Ser Ile Tyr Gly Tyr Arg Lys Leu Ile Leu Gly Val Glu Glu
              20                  25                  30

 cag atg ttc tgt cat tgc cac att ctt ctg gac aca gac tgg aga act      144
 Gln Met Phe Cys His Cys His Ile Leu Leu Asp Thr Asp Trp Arg Thr
          35                  40                  45

 ata gga atg tat gtt gaa gaa agt acg cac atc tta tct tct gaa cat      192
 Ile Gly Met Tyr Val Glu Glu Ser Thr His Ile Leu Ser Ser Glu His
      50                  55                  60

 ttt gat gga att aac cac aaa ctt cat gca aga aca att tgc ttc aca      240
 Phe Asp Gly Ile Asn His Lys Leu His Ala Arg Thr Ile Cys Phe Thr
  65                  70                  75                  80

 aag gcc tac ctt aaa tca act gca aat gga tac tac ttc aca gag tag      288
 Lys Ala Tyr Leu Lys Ser Thr Ala Asn Gly Tyr Tyr Phe Thr Glu 
                  85                  90                  95





      <210> 363
      <211> 855
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(855)

      <400> 363
  atg gct ctg cgg agg ctg ggg gcc gcg ctg ctg ctg ctg ccg ctg ctc      48
  Met Ala Leu Arg Arg Leu Gly Ala Ala Leu Leu Leu Leu Pro Leu Leu
    1               5                  10                  15

 gcc gcc gtg gaa gga atg gcc gag ctt gca ggg caa gaa gcg aac gtg       96
 Ala Ala Val Glu Gly Met Ala Glu Leu Ala Gly Gln Glu Ala Asn Val
              20                  25                  30

 aat aat ggt tct cac gtg tac tgc act tta cag ttt tca aac cac ttt      144
 Asn Asn Gly Ser His Val Tyr Cys Thr Leu Gln Phe Ser Asn His Phe
          35                  40                  45

 aca gtt tat gaa gta ctt cgc act ata cgc agc tct ctg tgg ttt aca      192
 Thr Val Tyr Glu Val Leu Arg Thr Ile Arg Ser Ser Leu Trp Phe Thr
      50                  55                  60

 acg tgc tgc aca gtt gac aag cct aag aaa aaa cgc ata tca gac cag      240
 Thr Cys Cys Thr Val Asp Lys Pro Lys Lys Lys Arg Ile Ser Asp Gln
  65                  70                  75                  80

 acg tgg ggg ctg cgg cct ctg gga aag gcg tcg tgg ggg acc ctg tgc      288
 Thr Trp Gly Leu Arg Pro Leu Gly Lys Ala Ser Trp Gly Thr Leu Cys
                  85                  90                  95

 tac aac ttc agt ttc tct ttc ggt aat gag cac ttt agt gac cgc agt      336
 Tyr Asn Phe Ser Phe Ser Phe Gly Asn Glu His Phe Ser Asp Arg Ser
             100                 105                 110

 cag ggg gtg ggg ggt gtc cct gga tgg cag cca cag ttt ctg gca ctg      384
 Gln Gly Val Gly Gly Val Pro Gly Trp Gln Pro Gln Phe Leu Ala Leu
         115                 120                 125

 agg cag ctg tcc ttc ggc tcc tgg ggg att tgg cgg ctg act gcg gtt      432
 Arg Gln Leu Ser Phe Gly Ser Trp Gly Ile Trp Arg Leu Thr Ala Val
     130                 135                 140

 tcc cgg agt ggg gcc act ggg gca cct agg gtg cca cgg gcc ctg ggt      480
 Ser Arg Ser Gly Ala Thr Gly Ala Pro Arg Val Pro Arg Ala Leu Gly
 145                 150                 155                 160

 gtg gag ggc agc cct ggg gcc tgg ctg ctg gcg gga gct ctg tgg aat      528
 Val Glu Gly Ser Pro Gly Ala Trp Leu Leu Ala Gly Ala Leu Trp Asn
                 165                 170                 175

 atg gct gag ctc ttt gag cct cag ctt ctt gaa cta tac aat gag gtt      576
 Met Ala Glu Leu Phe Glu Pro Gln Leu Leu Glu Leu Tyr Asn Glu Val
             180                 185                 190

 aga caa ggc gtc ctg gaa gag gcg act tct aag atg att ctt aag gaa      624
 Arg Gln Gly Val Leu Glu Glu Ala Thr Ser Lys Met Ile Leu Lys Glu
         195                 200                 205

 gag cca ggt gaa gaa gca gca agg cag cca ttc cag gca aca gga aca      672
 Glu Pro Gly Glu Glu Ala Ala Arg Gln Pro Phe Gln Ala Thr Gly Thr
     210                 215                 220

 gca tct gca aag atc cgg ata gga ggc ccg ggc cct gaa ttg gcc tcc      720
 Ala Ser Ala Lys Ile Arg Ile Gly Gly Pro Gly Pro Glu Leu Ala Ser
 225                 230                 235                 240

 ttg caa atc cgc ctg cat gac agc tcc cag tgg cct gcg gga gga gtg      768
 Leu Gln Ile Arg Leu His Asp Ser Ser Gln Trp Pro Ala Gly Gly Val
                 245                 250                 255

 ttt tct cgg ctc cct gac ggc atc tgt ccc aag atg ggg aaa cca aga      816
 Phe Ser Arg Leu Pro Asp Gly Ile Cys Pro Lys Met Gly Lys Pro Arg
             260                 265                 270

 ccc aaa gag gat aag gac ctg tgc aaa gtc aca cag tga                  855
 Pro Lys Glu Asp Lys Asp Leu Cys Lys Val Thr Gln 
         275                 280





      <210> 364
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 364
  atg aga acc tgg aga aag ggg tcg ccg gct gag ctg tcc ttt gct ctc      48
  Met Arg Thr Trp Arg Lys Gly Ser Pro Ala Glu Leu Ser Phe Ala Leu
    1               5                  10                  15

 ctg cct ctg ctg ggg cct caa cac ctg tgt cca gag cct ctc cac cca       96
 Leu Pro Leu Leu Gly Pro Gln His Leu Cys Pro Glu Pro Leu His Pro
              20                  25                  30

 cct gca ctc tct ggg tcc tcc tct ttt gca tca agg gct ccc tgg ggg      144
 Pro Ala Leu Ser Gly Ser Ser Ser Phe Ala Ser Arg Ala Pro Trp Gly
          35                  40                  45

 gat gag gca gct agc gtg gct tct gtc acc agt ttg aag gtg ctt gtc      192
 Asp Glu Ala Ala Ser Val Ala Ser Val Thr Ser Leu Lys Val Leu Val
      50                  55                  60

 aat ggg gtc cca tcc cgt gtg tcc att cag cac cct ctg gag cac tga      240
 Asn Gly Val Pro Ser Arg Val Ser Ile Gln His Pro Leu Glu His 
  65                  70                  75





      <210> 365
      <211> 225
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(225)

      <400> 365
  atg tcg gtg tta gaa gaa aat cgg ccg ttt gct caa caa tta tcc aat      48
  Met Ser Val Leu Glu Glu Asn Arg Pro Phe Ala Gln Gln Leu Ser Asn
    1               5                  10                  15

 gtc tac ttt aca ata ctt tcg ctg ttc tgt ttt aag ctt ttt gtg aaa       96
 Val Tyr Phe Thr Ile Leu Ser Leu Phe Cys Phe Lys Leu Phe Val Lys
              20                  25                  30

 atc agc ctt gcc atc ctc agt cat ttc tac ata gtg aaa ggc aac cgc      144
 Ile Ser Leu Ala Ile Leu Ser His Phe Tyr Ile Val Lys Gly Asn Arg
          35                  40                  45

 aag gaa gcg gca agg ata gca gct gaa ttt tat gga gta acc caa gga      192
 Lys Glu Ala Ala Arg Ile Ala Ala Glu Phe Tyr Gly Val Thr Gln Gly
      50                  55                  60

 caa gaa caa ctc tac ttt cat aaa tct tca taa                          225
 Gln Glu Gln Leu Tyr Phe His Lys Ser Ser 
  65                  70





      <210> 366
      <211> 918
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(918)

      <400> 366
  atg agc aga gac cac agg ctg ctg tgc ctc ctg ggc ctc tgt tgt gtg      48
  Met Ser Arg Asp His Arg Leu Leu Cys Leu Leu Gly Leu Cys Cys Val
    1               5                  10                  15

 gca gat gct tcc aaa cag ccc ttc agg aaa tct gga att ccc aga ggt       96
 Ala Asp Ala Ser Lys Gln Pro Phe Arg Lys Ser Gly Ile Pro Arg Gly
              20                  25                  30

 tat aca ttg cac ctg agg cca tct ggc tac aat cca aac tct ggg tgc      144
 Tyr Thr Leu His Leu Arg Pro Ser Gly Tyr Asn Pro Asn Ser Gly Cys
          35                  40                  45

 ggc tgg cgc caa agc tac tac acc atg ctg cct tct aag ctg cat ttc      192
 Gly Trp Arg Gln Ser Tyr Tyr Thr Met Leu Pro Ser Lys Leu His Phe
      50                  55                  60

 atc tgg aac cgc tgt ggc tgg cag gcc gag cct ctg aac act gca att      240
 Ile Trp Asn Arg Cys Gly Trp Gln Ala Glu Pro Leu Asn Thr Ala Ile
  65                  70                  75                  80

 cag gtt aat cat gca gac ctg ctg gag cac gcg ggg ccg agg gga ggc      288
 Gln Val Asn His Ala Asp Leu Leu Glu His Ala Gly Pro Arg Gly Gly
                  85                  90                  95

 cca cac tac cgc ttt ccc cac tct ggg gac ggg gag aac ctg att tgt      336
 Pro His Tyr Arg Phe Pro His Ser Gly Asp Gly Glu Asn Leu Ile Cys
             100                 105                 110

 ctt cgg tcc aca gct agt gtg tgc aag ggc cca att cag gtc cag atc      384
 Leu Arg Ser Thr Ala Ser Val Cys Lys Gly Pro Ile Gln Val Gln Ile
         115                 120                 125

 ggc gtg ctg aca agg act gtg ttt ggg gct gct ccc ctg cag aca gag      432
 Gly Val Leu Thr Arg Thr Val Phe Gly Ala Ala Pro Leu Gln Thr Glu
     130                 135                 140

 ccc cat ggg cag gcc ctg atg ggc ggt cag agg aca caa gac aag agc      480
 Pro His Gly Gln Ala Leu Met Gly Gly Gln Arg Thr Gln Asp Lys Ser
 145                 150                 155                 160

 cag aca cgt gag atg act gag ttc ttg aat gcc ctc cag aaa tta aac      528
 Gln Thr Arg Glu Met Thr Glu Phe Leu Asn Ala Leu Gln Lys Leu Asn
                 165                 170                 175

 caa gac ctt ctg gaa cat tct tgg gag gaa ggt aac aag cag att ccc      576
 Gln Asp Leu Leu Glu His Ser Trp Glu Glu Gly Asn Lys Gln Ile Pro
             180                 185                 190

 gaa ggt gac aat gga ggg agt aga agc ctt cag ccc aga tgc tat tct      624
 Glu Gly Asp Asn Gly Gly Ser Arg Ser Leu Gln Pro Arg Cys Tyr Ser
         195                 200                 205

 gac atg aaa cct ttc act caa ata ttt ctc tac aat gga gtc tct cca      672
 Asp Met Lys Pro Phe Thr Gln Ile Phe Leu Tyr Asn Gly Val Ser Pro
     210                 215                 220

 cag tcg ggc cat ggc tcc act gtg gaa gat gtg gag ttt gca gca cgg      720
 Gln Ser Gly His Gly Ser Thr Val Glu Asp Val Glu Phe Ala Ala Arg
 225                 230                 235                 240

 cat ggt gtc aaa cag cca cat gca cag cag tcc tgc agg cac tac ctt      768
 His Gly Val Lys Gln Pro His Ala Gln Gln Ser Cys Arg His Tyr Leu
                 245                 250                 255

 gca gct gcc acc atg atc gtg gac aga acg ctc ctc ttg gcc cca gtc      816
 Ala Ala Ala Thr Met Ile Val Asp Arg Thr Leu Leu Leu Ala Pro Val
             260                 265                 270

 ctc ttt gcc ttc cat cat gac tgg aag ctt cct gag gcc tca cca gca      864
 Leu Phe Ala Phe His His Asp Trp Lys Leu Pro Glu Ala Ser Pro Ala
         275                 280                 285

 gca gat gct ggc gtc atg ctt ctt gta caa cct gca gaa cca tgg gcc      912
 Ala Asp Ala Gly Val Met Leu Leu Val Gln Pro Ala Glu Pro Trp Ala
     290                 295                 300

 aag taa                                                              918
 Lys 
 305





      <210> 367
      <211> 330
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(330)

      <400> 367
  atg gca ccg gct ctc ctg tct ggg gtc tca gtg ctc ctc agg ctg tac      48
  Met Ala Pro Ala Leu Leu Ser Gly Val Ser Val Leu Leu Arg Leu Tyr
    1               5                  10                  15

 gta gca cct cct cag gca ggg ccc aca gcg tgg ctt gca ctg ccc cac       96
 Val Ala Pro Pro Gln Ala Gly Pro Thr Ala Trp Leu Ala Leu Pro His
              20                  25                  30

 agt gag ctt ccc gag agt gtc ccg aga gac cca agc aga tgc tac gag      144
 Ser Glu Leu Pro Glu Ser Val Pro Arg Asp Pro Ser Arg Cys Tyr Glu
          35                  40                  45

 gct tcc tat gac cca gcc tca gaa att cca gcg tgt cat ttc tac cgc      192
 Ala Ser Tyr Asp Pro Ala Ser Glu Ile Pro Ala Cys His Phe Tyr Arg
      50                  55                  60

 act ctt tca gtc cct agg ggg gag cag acg ccg gtg tgt gtt gct gtg      240
 Thr Leu Ser Val Pro Arg Gly Glu Gln Thr Pro Val Cys Val Ala Val
  65                  70                  75                  80

 aac tct gtg ctg tgc cca ttc acc ctc aca aag ggc ctc tgc aag cag      288
 Asn Ser Val Leu Cys Pro Phe Thr Leu Thr Lys Gly Leu Cys Lys Gln
                  85                  90                  95

 ctt gac atg ggc att gca gcc cgc agg cgt ctg gcc agt tga              330
 Leu Asp Met Gly Ile Ala Ala Arg Arg Arg Leu Ala Ser 
             100                 105





      <210> 368
      <211> 246
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(246)

      <400> 368
  atg gct tta aaa atc atg tta caa gcc atc ttt gtt ggt ttg aat ggc      48
  Met Ala Leu Lys Ile Met Leu Gln Ala Ile Phe Val Gly Leu Asn Gly
    1               5                  10                  15

 att gaa aca ggc agg aca cca gca agc ccc caa tca ggc aca tcc aga       96
 Ile Glu Thr Gly Arg Thr Pro Ala Ser Pro Gln Ser Gly Thr Ser Arg
              20                  25                  30

 gag atg tgg gct caa gaa cca gta aca caa gag gaa agg gta ggg aaa      144
 Glu Met Trp Ala Gln Glu Pro Val Thr Gln Glu Glu Arg Val Gly Lys
          35                  40                  45

 ctc act tcc ttc ctt tgg gca gaa gga gga ggg ggg tgc tcc aag ggt      192
 Leu Thr Ser Phe Leu Trp Ala Glu Gly Gly Gly Gly Cys Ser Lys Gly
      50                  55                  60

 gcg ctc ctg ggg aga agc gct ttg gtg ctg gca gca gca gtg gct gca      240
 Ala Leu Leu Gly Arg Ser Ala Leu Val Leu Ala Ala Ala Val Ala Ala
  65                  70                  75                  80

 gag tga                                                              246
 Glu 






      <210> 369
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 369
  atg gct tca cgt ggg gtt gtt ggc att ttc ttc ctc tct gct gtc ccc      48
  Met Ala Ser Arg Gly Val Val Gly Ile Phe Phe Leu Ser Ala Val Pro
    1               5                  10                  15

 ctt gtg tgt ctg gag ctc cgg cgt ggg atc ccg gat ata gga atg ttg       96
 Leu Val Cys Leu Glu Leu Arg Arg Gly Ile Pro Asp Ile Gly Met Leu
              20                  25                  30

 cat aga acg acc gcc tct tcg gct gcg tgg ctt cgg agc agc ttt gac      144
 His Arg Thr Thr Ala Ser Ser Ala Ala Trp Leu Arg Ser Ser Phe Asp
          35                  40                  45

 tac aac tcc cag act gca tcg ccc ctg ccc ccc cac ttc cgg agc tga      192
 Tyr Asn Ser Gln Thr Ala Ser Pro Leu Pro Pro His Phe Arg Ser 
      50                  55                  60





      <210> 370
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 370
  atg gcc tat tgt tca acc tgc ctg ttt ttc tat gtc ttt caa gtt aag      48
  Met Ala Tyr Cys Ser Thr Cys Leu Phe Phe Tyr Val Phe Gln Val Lys
    1               5                  10                  15

 aat aga ttt tac aga ctc ttt gaa ttc aga aag atg att gga aat cgg       96
 Asn Arg Phe Tyr Arg Leu Phe Glu Phe Arg Lys Met Ile Gly Asn Arg
              20                  25                  30

 gaa aga tgc cag aat ctg gtt tca agc gat tat cca gta cac att gat      144
 Glu Arg Cys Gln Asn Leu Val Ser Ser Asp Tyr Pro Val His Ile Asp
          35                  40                  45

 aag att gaa gag caa tca gat tgt aag atc tta gat gga cac ttt gtt      192
 Lys Ile Glu Glu Gln Ser Asp Cys Lys Ile Leu Asp Gly His Phe Val
      50                  55                  60

 tcc ccc atg gct cac tat gtg cct gat atc atg cca att gaa tct gtt      240
 Ser Pro Met Ala His Tyr Val Pro Asp Ile Met Pro Ile Glu Ser Val
  65                  70                  75                  80

 att gca agc aat gat aaa ata gtg ata cat gta tgg gca ttt gaa aaa      288
 Ile Ala Ser Asn Asp Lys Ile Val Ile His Val Trp Ala Phe Glu Lys
                  85                  90                  95

 ttc ttc agt caa gaa gag att att ctg taa                              318
 Phe Phe Ser Gln Glu Glu Ile Ile Leu 
             100                 105





      <210> 371
      <211> 1437
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1437)

      <400> 371
  atg gct ctg tta gct tct gtg gct ctg cca tgg ctg ttc tgg ctg cca      48
  Met Ala Leu Leu Ala Ser Val Ala Leu Pro Trp Leu Phe Trp Leu Pro
    1               5                  10                  15

 ctc cag ccc tcg ttc atg ttg ctt gat agc acg gcc cat gct gct cca       96
 Leu Gln Pro Ser Phe Met Leu Leu Asp Ser Thr Ala His Ala Ala Pro
              20                  25                  30

 cag agg aaa tgg ctg ctt ctg cta gcc tcc tct ggt cta ggt gat gtg      144
 Gln Arg Lys Trp Leu Leu Leu Leu Ala Ser Ser Gly Leu Gly Asp Val
          35                  40                  45

 ggg gac gat gat tcc cat ggg aag cat ggg aag cac aat aga ggc aca      192
 Gly Asp Asp Asp Ser His Gly Lys His Gly Lys His Asn Arg Gly Thr
      50                  55                  60

 ctc tat tgt gtc tat cca aac ctt act aat ttg gag ttt tgt ggg gtg      240
 Leu Tyr Cys Val Tyr Pro Asn Leu Thr Asn Leu Glu Phe Cys Gly Val
  65                  70                  75                  80

 gtt tct cag gaa cca cct tgc tct gct cag ctc ctt gcc gca gtg ctg      288
 Val Ser Gln Glu Pro Pro Cys Ser Ala Gln Leu Leu Ala Ala Val Leu
                  85                  90                  95

 ggt tgg gaa gtg cag ctg tct gct tca gaa agt gag ggc tcc agg aat      336
 Gly Trp Glu Val Gln Leu Ser Ala Ser Glu Ser Glu Gly Ser Arg Asn
             100                 105                 110

 gag gag aat ctt caa gaa ctt cct cgc act gtg aca tgt ctg atc cct      384
 Glu Glu Asn Leu Gln Glu Leu Pro Arg Thr Val Thr Cys Leu Ile Pro
         115                 120                 125

 tgc tcc cat ccc tgc agc atg aac aag att att gcc caa tgt ccc ata      432
 Cys Ser His Pro Cys Ser Met Asn Lys Ile Ile Ala Gln Cys Pro Ile
     130                 135                 140

 cgg gga cag aat tac ccc ttg gtt gga aac tgc tgc aca agt gga agg      480
 Arg Gly Gln Asn Tyr Pro Leu Val Gly Asn Cys Cys Thr Ser Gly Arg
 145                 150                 155                 160

 tgg tca aat ata agc cca gag aag gag gca agg gcc aga tcc tat gag      528
 Trp Ser Asn Ile Ser Pro Glu Lys Glu Ala Arg Ala Arg Ser Tyr Glu
                 165                 170                 175

 cca ctg aag gat tta aaa cag ggg aga gtt gtt tcc gga gcc tac aaa      576
 Pro Leu Lys Asp Leu Lys Gln Gly Arg Val Val Ser Gly Ala Tyr Lys
             180                 185                 190

 aac aga aac act gaa aag cct ggc tgc atg ggt aga aag ccg atg agt      624
 Asn Arg Asn Thr Glu Lys Pro Gly Cys Met Gly Arg Lys Pro Met Ser
         195                 200                 205

 gat ccc cag ttg cca aag agg cat aat cag atc tgg ttt tgg aaa gaa      672
 Asp Pro Gln Leu Pro Lys Arg His Asn Gln Ile Trp Phe Trp Lys Glu
     210                 215                 220

 cac agc att ggc cat atg aag ggg cct gaa gag gct gga gac tat aag      720
 His Ser Ile Gly His Met Lys Gly Pro Glu Glu Ala Gly Asp Tyr Lys
 225                 230                 235                 240

 aca gta gct caa gtc cta cag cct atg tta agg cat ctg aga ggc cta      768
 Thr Val Ala Gln Val Leu Gln Pro Met Leu Arg His Leu Arg Gly Leu
                 245                 250                 255

 gct gtg aat cat gat aac ttc ttt gaa ata tgg ctg cag cta ctg acc      816
 Ala Val Asn His Asp Asn Phe Phe Glu Ile Trp Leu Gln Leu Leu Thr
             260                 265                 270

 atc tgt cgg gtt cta act gag gtc gga gga gag tcg gtg gat gag tgg      864
 Ile Cys Arg Val Leu Thr Glu Val Gly Gly Glu Ser Val Asp Glu Trp
         275                 280                 285

 cag gca gct gaa aga cca gtc aag gaa tca tgg ggg cat ttc aac atg      912
 Gln Ala Ala Glu Arg Pro Val Lys Glu Ser Trp Gly His Phe Asn Met
     290                 295                 300

 gct tta ttc tct gga cac acg gga gct gtg ggt gca agc aag cca tgg      960
 Ala Leu Phe Ser Gly His Thr Gly Ala Val Gly Ala Ser Lys Pro Trp
 305                 310                 315                 320

 gca caa gca agc cat ggg tac aag cct gag gat gag cca cag gtg caa     1008
 Ala Gln Ala Ser His Gly Tyr Lys Pro Glu Asp Glu Pro Gln Val Gln
                 325                 330                 335

 gcc gtt aca tac agc att agc agg gac ttt gag caa tca tca cag tct     1056
 Ala Val Thr Tyr Ser Ile Ser Arg Asp Phe Glu Gln Ser Ser Gln Ser
             340                 345                 350

 tcc aca atg gct gaa ctg att tac act ccc acc gag agt gta gca att     1104
 Ser Thr Met Ala Glu Leu Ile Tyr Thr Pro Thr Glu Ser Val Ala Ile
         355                 360                 365

 acc atc aca gct cct cct gga ggt cca cta aaa cta gcc ctt tgt gaa     1152
 Thr Ile Thr Ala Pro Pro Gly Gly Pro Leu Lys Leu Ala Leu Cys Glu
     370                 375                 380

 ggt gaa tcg tgg act tcc cag cac att ttc tta tct cac att tat tct     1200
 Gly Glu Ser Trp Thr Ser Gln His Ile Phe Leu Ser His Ile Tyr Ser
 385                 390                 395                 400

 caa gca atc ttt gtt agc aaa cgc ttt cat acc ctg gat gtg aag ctt     1248
 Gln Ala Ile Phe Val Ser Lys Arg Phe His Thr Leu Asp Val Lys Leu
                 405                 410                 415

 tct ttc agg agg aaa ttt gga gac aga gac aca cag gga gaa cgc cat     1296
 Ser Phe Arg Arg Lys Phe Gly Asp Arg Asp Thr Gln Gly Glu Arg His
             420                 425                 430

 gtg gag gtg aag ata aag aac aca acg gtg ctt cta caa gcc aag gaa     1344
 Val Glu Val Lys Ile Lys Asn Thr Thr Val Leu Leu Gln Ala Lys Glu
         435                 440                 445

 tgc caa gga cct cca gca aac cac caa gaa gct cag ggg gag gca cag     1392
 Cys Gln Gly Pro Pro Ala Asn His Gln Glu Ala Gln Gly Glu Ala Gln
     450                 455                 460

 aac gaa ttc ttt ctc aca gac ctc aga agg aac caa cgc tgc tga         1437
 Asn Glu Phe Phe Leu Thr Asp Leu Arg Arg Asn Gln Arg Cys 
 465                 470                 475





      <210> 372
      <211> 351
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(351)

      <400> 372
  atg acc gca gaa ttc ctc tcc ctg ctt tgc ctc gga tca ctc cca gaa      48
  Met Thr Ala Glu Phe Leu Ser Leu Leu Cys Leu Gly Ser Leu Pro Glu
    1               5                  10                  15

 cct ttg ctc tca gtc aat gta gac cct ggg atg act cca ggt ctc agg       96
 Pro Leu Leu Ser Val Asn Val Asp Pro Gly Met Thr Pro Gly Leu Arg
              20                  25                  30

 aca ctt cga tgt ctc act cca tac aat gga acc gaa tgt att gta att      144
 Thr Leu Arg Cys Leu Thr Pro Tyr Asn Gly Thr Glu Cys Ile Val Ile
          35                  40                  45

 gct ctg ttg aaa atg ggg atc cca gaa cca tta caa gtc agg caa gta      192
 Ala Leu Leu Lys Met Gly Ile Pro Glu Pro Leu Gln Val Arg Gln Val
      50                  55                  60

 aga aaa aac cag act gat ttc atg ctc tgg aac gtg aca agt aat gac      240
 Arg Lys Asn Gln Thr Asp Phe Met Leu Trp Asn Val Thr Ser Asn Asp
  65                  70                  75                  80

 agt gga aac tac agc tgt gtg tat tac ctg agc aac tca tca cac ttg      288
 Ser Gly Asn Tyr Ser Cys Val Tyr Tyr Leu Ser Asn Ser Ser His Leu
                  85                  90                  95

 gcc tcc ttc ccc agc aac aag ctg gag atc tgg gtg aca gct gca aag      336
 Ala Ser Phe Pro Ser Asn Lys Leu Glu Ile Trp Val Thr Ala Ala Lys
             100                 105                 110

 aag aga tct tct taa                                                  351
 Lys Arg Ser Ser 
         115





      <210> 373
      <211> 909
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(909)

      <400> 373
  atg gcc aca ctt ctg ttg gcg gtg gtc act ccc cat cta cat tcc cat      48
  Met Ala Thr Leu Leu Leu Ala Val Val Thr Pro His Leu His Ser His
    1               5                  10                  15

 aac atg ggc aca tgc ggg tac tac acc cac act gct acc ttg tgg agt       96
 Asn Met Gly Thr Cys Gly Tyr Tyr Thr His Thr Ala Thr Leu Trp Ser
              20                  25                  30

 tct gtt tct tcc cct ggg gca ctg gtt ctt aca agg gga cat aga ttg      144
 Ser Val Ser Ser Pro Gly Ala Leu Val Leu Thr Arg Gly His Arg Leu
          35                  40                  45

 ctc agc aac tct gtt act agc act gtc ctc att aat att tgc atc tct      192
 Leu Ser Asn Ser Val Thr Ser Thr Val Leu Ile Asn Ile Cys Ile Ser
      50                  55                  60

 gga tgt atg ctg ctc cac gta gga acc act gca cac gtg gct gtc gag      240
 Gly Cys Met Leu Leu His Val Gly Thr Thr Ala His Val Ala Val Glu
  65                  70                  75                  80

 cac ttg ata ggt ggt gtc cag gat gat gag gac tta gaa atg acc ata      288
 His Leu Ile Gly Gly Val Gln Asp Asp Glu Asp Leu Glu Met Thr Ile
                  85                  90                  95

 gga tgt cat ggt gaa gag atg att ggt gac ctt gat aag aac agt ttt      336
 Gly Cys His Gly Glu Glu Met Ile Gly Asp Leu Asp Lys Asn Ser Phe
             100                 105                 110

 ggc gct ggt ggt ttg tgc atc gga gag aga gta gga ggg cct ggg tgc      384
 Gly Ala Gly Gly Leu Cys Ile Gly Glu Arg Val Gly Gly Pro Gly Cys
         115                 120                 125

 tgt gaa gtc cta att aga atg act cca aca gag gat gtg gga gaa gag      432
 Cys Glu Val Leu Ile Arg Met Thr Pro Thr Glu Asp Val Gly Glu Glu
     130                 135                 140

 agg tct gac atg aag gga ata caa ctg agc atg caa gag agg acc aga      480
 Arg Ser Asp Met Lys Gly Ile Gln Leu Ser Met Gln Glu Arg Thr Arg
 145                 150                 155                 160

 tgt aga caa ttt cct gaa gga agg aga cat cag ctg ggc cac ctg ctt      528
 Cys Arg Gln Phe Pro Glu Gly Arg Arg His Gln Leu Gly His Leu Leu
                 165                 170                 175

 cag gga ggc ctg gga aga ggg gag gct tgg aaa tat cac cag att tgg      576
 Gln Gly Gly Leu Gly Arg Gly Glu Ala Trp Lys Tyr His Gln Ile Trp
             180                 185                 190

 gaa gaa ggt cac tgg cta ttg agg gag cag ccc aga ggt gta gaa gct      624
 Glu Glu Gly His Trp Leu Leu Arg Glu Gln Pro Arg Gly Val Glu Ala
         195                 200                 205

 ctg ttc tgg aga ggt gac aca gag gac ccg tct ctc ttt ccc tac aca      672
 Leu Phe Trp Arg Gly Asp Thr Glu Asp Pro Ser Leu Phe Pro Tyr Thr
     210                 215                 220

 gcc ccc att caa aag gta gaa ttt cta ttc cag ccc agc atc aag cat      720
 Ala Pro Ile Gln Lys Val Glu Phe Leu Phe Gln Pro Ser Ile Lys His
 225                 230                 235                 240

 aca gaa aac ttt ccc ctg att cat gat ttc tac act gga aaa agt gag      768
 Thr Glu Asn Phe Pro Leu Ile His Asp Phe Tyr Thr Gly Lys Ser Glu
                 245                 250                 255

 att aag gtg gcc aac cag ctt tcc cac cat ctt ggg ttc cct gac aga      816
 Ile Lys Val Ala Asn Gln Leu Ser His His Leu Gly Phe Pro Asp Arg
             260                 265                 270

 aga cct gtc cct acc tca atc tac agg aag cac tgg gag tac ctg aag      864
 Arg Pro Val Pro Thr Ser Ile Tyr Arg Lys His Trp Glu Tyr Leu Lys
         275                 280                 285

 gga gaa cta tcc ctg aaa aca gcc aga gac aaa gga gtc aag tag          909
 Gly Glu Leu Ser Leu Lys Thr Ala Arg Asp Lys Gly Val Lys 
     290                 295                 300





      <210> 374
      <211> 939
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(939)

      <400> 374
  atg ggg tgc act ctt cag agc ggg tgt ctc tta ctt ttg cgc aga gga      48
  Met Gly Cys Thr Leu Gln Ser Gly Cys Leu Leu Leu Leu Arg Arg Gly
    1               5                  10                  15

 cag gcc cag atg aga aag ttt cac aca tat gat tta gac ctt acg atc       96
 Gln Ala Gln Met Arg Lys Phe His Thr Tyr Asp Leu Asp Leu Thr Ile
              20                  25                  30

 agc cat tgt tta cat cgg gaa gca tca atc cgg agt aac tgg caa gca      144
 Ser His Cys Leu His Arg Glu Ala Ser Ile Arg Ser Asn Trp Gln Ala
          35                  40                  45

 ggt aca cat tca agt gat aca gtg ata tct ctg ctg cag ttt cct atg      192
 Gly Thr His Ser Ser Asp Thr Val Ile Ser Leu Leu Gln Phe Pro Met
      50                  55                  60

 att cga ggg gaa aag tca ttt ggg att ttt gtt cca gaa tct cat cag      240
 Ile Arg Gly Glu Lys Ser Phe Gly Ile Phe Val Pro Glu Ser His Gln
  65                  70                  75                  80

 aat aga tat ttt agt tac gtt aag cgg ttg ctg ctg cta acc cag tca      288
 Asn Arg Tyr Phe Ser Tyr Val Lys Arg Leu Leu Leu Leu Thr Gln Ser
                  85                  90                  95

 atg gtg aca atg ttg atg aaa cca ggg gaa ctg aga aga ttt tct cat      336
 Met Val Thr Met Leu Met Lys Pro Gly Glu Leu Arg Arg Phe Ser His
             100                 105                 110

 gga cca tca caa gtg aaa gca gtg tta gaa aac agc ttc agg gct tgg      384
 Gly Pro Ser Gln Val Lys Ala Val Leu Glu Asn Ser Phe Arg Ala Trp
         115                 120                 125

 gga ggc agc gtt gtt tta gac tgg ctg gaa agt cat gct gag cag caa      432
 Gly Gly Ser Val Val Leu Asp Trp Leu Glu Ser His Ala Glu Gln Gln
     130                 135                 140

 gag gac aga tct ctt tta gag gag aca gcc cca cct ggc tgc acc ctc      480
 Glu Asp Arg Ser Leu Leu Glu Glu Thr Ala Pro Pro Gly Cys Thr Leu
 145                 150                 155                 160

 caa gga ggc cac agg gca tat cat cca gag gca gca gat ggt aca gct      528
 Gln Gly Gly His Arg Ala Tyr His Pro Glu Ala Ala Asp Gly Thr Ala
                 165                 170                 175

 ctc ttt gaa ctt tac tgc cca ggt gaa cgt tct ctg cat tta gat ctt      576
 Leu Phe Glu Leu Tyr Cys Pro Gly Glu Arg Ser Leu His Leu Asp Leu
             180                 185                 190

 cag gag ttt tac aga cta gtg tgg agt gga cat agc agg aca gtg ttg      624
 Gln Glu Phe Tyr Arg Leu Val Trp Ser Gly His Ser Arg Thr Val Leu
         195                 200                 205

 gga tgg gct gat tgt gag tat gga gtt ctt tct gga gga gct cca gca      672
 Gly Trp Ala Asp Cys Glu Tyr Gly Val Leu Ser Gly Gly Ala Pro Ala
     210                 215                 220

 gga gct ggg caa ata ctg gga gct ttg act aag ggg cat gca ttg cag      720
 Gly Ala Gly Gln Ile Leu Gly Ala Leu Thr Lys Gly His Ala Leu Gln
 225                 230                 235                 240

 atg agg ttt gac cag agg ttt tcc agg atc cct gaa gaa ctc tgc act      768
 Met Arg Phe Asp Gln Arg Phe Ser Arg Ile Pro Glu Glu Leu Cys Thr
                 245                 250                 255

 tct aag cct gta agg cca caa cag aac aaa tat ctg tcc tca gtt cct      816
 Ser Lys Pro Val Arg Pro Gln Gln Asn Lys Tyr Leu Ser Ser Val Pro
             260                 265                 270

 ctg tct gcc aac caa gct gtc agc caa tct tac tgg ctc tcc ttc aaa      864
 Leu Ser Ala Asn Gln Ala Val Ser Gln Ser Tyr Trp Leu Ser Phe Lys
         275                 280                 285

 ata tat aga gaa tcc aat ctt acc atc ttt gct gtc ccc atg gtc cca      912
 Ile Tyr Arg Glu Ser Asn Leu Thr Ile Phe Ala Val Pro Met Val Pro
     290                 295                 300

 gca act atc acc ccc ccc cca gat tag                                  939
 Ala Thr Ile Thr Pro Pro Pro Asp 
 305                 310





      <210> 375
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 375
  atg aca cca ttc ctc ggg gtg atc agc cag cta ctt ggt ggt agg ctg      48
  Met Thr Pro Phe Leu Gly Val Ile Ser Gln Leu Leu Gly Gly Arg Leu
    1               5                  10                  15

 ctt ata tcg gac ctc ttc cat cat gga aag ggc agc ggt ttg tcc tca       96
 Leu Ile Ser Asp Leu Phe His His Gly Lys Gly Ser Gly Leu Ser Ser
              20                  25                  30

 cca gaa cag aca ctt act ctg gat atg ggt ttg ctt atc ctg cat gca      144
 Pro Glu Gln Thr Leu Thr Leu Asp Met Gly Leu Leu Ile Leu His Ala
          35                  40                  45

 atg ctt ctg cca aga cta cca tct gtg gac tca cgg aat gca tta ccc      192
 Met Leu Leu Pro Arg Leu Pro Ser Val Asp Ser Arg Asn Ala Leu Pro
      50                  55                  60

 acc atc atg gta ttc cac aca gca ttg ctt ctg acc aag gca ctc act      240
 Thr Ile Met Val Phe His Thr Ala Leu Leu Leu Thr Lys Ala Leu Thr
  65                  70                  75                  80

 tta cag cta aga acc agg att cat ggg tcc agg aat caa ggg gtg gaa      288
 Leu Gln Leu Arg Thr Arg Ile His Gly Ser Arg Asn Gln Gly Val Glu
                  85                  90                  95

 atg gaa gtg gca cca ctc ccc atc acc cct agt gac cgg cta gca aaa      336
 Met Glu Val Ala Pro Leu Pro Ile Thr Pro Ser Asp Arg Leu Ala Lys
             100                 105                 110

 ttt ttg cct cct gtt cct gcg aca tta tgt tct gct ggc cta aag gtc      384
 Phe Leu Pro Pro Val Pro Ala Thr Leu Cys Ser Ala Gly Leu Lys Val
         115                 120                 125

 tta gtt cca gag gga gga atg ctg tca cta gga gac aca aca atg att      432
 Leu Val Pro Glu Gly Gly Met Leu Ser Leu Gly Asp Thr Thr Met Ile
     130                 135                 140

 cca tta aac ctg aag tta aga tgg cca cct agc cac ttt ggg cta cct      480
 Pro Leu Asn Leu Lys Leu Arg Trp Pro Pro Ser His Phe Gly Leu Pro
 145                 150                 155                 160

 cta agt caa cag tct aag aag gga gtt ata gtg ttg gct ggg gtg act      528
 Leu Ser Gln Gln Ser Lys Lys Gly Val Ile Val Leu Ala Gly Val Thr
                 165                 170                 175

 gac cca gac tat caa gat gaa atc agt cta ctg ctc cac aat gga ggt      576
 Asp Pro Asp Tyr Gln Asp Glu Ile Ser Leu Leu Leu His Asn Gly Gly
             180                 185                 190

 atg gaa gag tat gca tgg aat aca gga gat ccc tta ggg cgt ctc tta      624
 Met Glu Glu Tyr Ala Trp Asn Thr Gly Asp Pro Leu Gly Arg Leu Leu
         195                 200                 205

 gta tta gca tgc cct gtg att aag gtc aat ggg aaa cta caa cag ccc      672
 Val Leu Ala Cys Pro Val Ile Lys Val Asn Gly Lys Leu Gln Gln Pro
     210                 215                 220

 aat cca ggt agg act aca aat gcc cca aac cct tta gga atg aag att      720
 Asn Pro Gly Arg Thr Thr Asn Ala Pro Asn Pro Leu Gly Met Lys Ile
 225                 230                 235                 240

 tgg gtc act cca cca ggt aaa taa                                      744
 Trp Val Thr Pro Pro Gly Lys 
                 245





      <210> 376
      <211> 756
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(756)

      <400> 376
  atg gag agc ctt ggg gga tgg gtg cct atg gtc atg ttt tgc tgc agc      48
  Met Glu Ser Leu Gly Gly Trp Val Pro Met Val Met Phe Cys Cys Ser
    1               5                  10                  15

 cgt acc agg tgc gaa acc ttc tgg gct gta tgc ggg ttt gag ctc tgc       96
 Arg Thr Arg Cys Glu Thr Phe Trp Ala Val Cys Gly Phe Glu Leu Cys
              20                  25                  30

 ctc tgc cta ttc gcc agc cgg ttc ctc ttg cca gtt cag atg tct gtg      144
 Leu Cys Leu Phe Ala Ser Arg Phe Leu Leu Pro Val Gln Met Ser Val
          35                  40                  45

 tgg gtc cag gga tct ccg gga gct agt atc cca gag ttc gtt gtg gtc      192
 Trp Val Gln Gly Ser Pro Gly Ala Ser Ile Pro Glu Phe Val Val Val
      50                  55                  60

 tgt gaa gac att ttc agt ggc aca ggt gtt gtc cta caa cct gtg aca      240
 Cys Glu Asp Ile Phe Ser Gly Thr Gly Val Val Leu Gln Pro Val Thr
  65                  70                  75                  80

 aca gtg gag ttt gtt tgc aaa ata aag atg caa ggc ttt ccc atg ttg      288
 Thr Val Glu Phe Val Cys Lys Ile Lys Met Gln Gly Phe Pro Met Leu
                  85                  90                  95

 tgg gag aca cag tcc tct cct ggt ggc cgt gtt tct ggt tgg ttt tct      336
 Trp Glu Thr Gln Ser Ser Pro Gly Gly Arg Val Ser Gly Trp Phe Ser
             100                 105                 110

 ctc acg agc cag tgt gct gtg ggg cac ccg ctc cca ctc cca ctc tca      384
 Leu Thr Ser Gln Cys Ala Val Gly His Pro Leu Pro Leu Pro Leu Ser
         115                 120                 125

 gtg ggc tca agg cct gag cag ccg aag gcc cat cag tgg tcc cag tta      432
 Val Gly Ser Arg Pro Glu Gln Pro Lys Ala His Gln Trp Ser Gln Leu
     130                 135                 140

 cct cag tgg gag ctc aag tgt ccc ctg tcc cca tgt ggc cac ttg atc      480
 Pro Gln Trp Glu Leu Lys Cys Pro Leu Ser Pro Cys Gly His Leu Ile
 145                 150                 155                 160

 tgc tgg att ctg agt cag aat gga gga aga gcc atg ggc aag ggc caa      528
 Cys Trp Ile Leu Ser Gln Asn Gly Gly Arg Ala Met Gly Lys Gly Gln
                 165                 170                 175

 gtc cac tgg cca ctg tca cca ggg gag cag ccc gaa gtc agg gcc gta      576
 Val His Trp Pro Leu Ser Pro Gly Glu Gln Pro Glu Val Arg Ala Val
             180                 185                 190

 cct ggg aac aag aag gac tcc aaa gac ctg gag cag atc tgg agc act      624
 Pro Gly Asn Lys Lys Asp Ser Lys Asp Leu Glu Gln Ile Trp Ser Thr
         195                 200                 205

 gtg agt tgg agg agt cgg gct cgg ata gca gcc tgc aag ggt gag ggt      672
 Val Ser Trp Arg Ser Arg Ala Arg Ile Ala Ala Cys Lys Gly Glu Gly
     210                 215                 220

 gct gag aaa gca aga tgg aca gag agg gac aga tgt ggc cca ttc agg      720
 Ala Glu Lys Ala Arg Trp Thr Glu Arg Asp Arg Cys Gly Pro Phe Arg
 225                 230                 235                 240

 gat cca gac cag tgt ctc atg gca tct gat gtc tag                      756
 Asp Pro Asp Gln Cys Leu Met Ala Ser Asp Val 
                 245                 250





      <210> 377
      <211> 399
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(399)

      <400> 377
  atg gtc tta ttt gaa acg acc ata att tca gct gta acg ttt tgt tct      48
  Met Val Leu Phe Glu Thr Thr Ile Ile Ser Ala Val Thr Phe Cys Ser
    1               5                  10                  15

 gta ctg ctg tca gca tac ttg gaa tta gaa aat cca cac ctg cca ttt       96
 Val Leu Leu Ser Ala Tyr Leu Glu Leu Glu Asn Pro His Leu Pro Phe
              20                  25                  30

 gaa gtt cat gtt tct ttt tct ccc ctt gcc ctt gtg tac cgt gta tgg      144
 Glu Val His Val Ser Phe Ser Pro Leu Ala Leu Val Tyr Arg Val Trp
          35                  40                  45

 aat gat cta tct tta aac gtg att ggg acc aaa tca agt cac tgg gca      192
 Asn Asp Leu Ser Leu Asn Val Ile Gly Thr Lys Ser Ser His Trp Ala
      50                  55                  60

 tgg aca ttc ttc tgg cat act acc cct gaa gag gga tgg gga gaa ctt      240
 Trp Thr Phe Phe Trp His Thr Thr Pro Glu Glu Gly Trp Gly Glu Leu
  65                  70                  75                  80

 ata gag gca gac aca ctg aca gca gaa aaa gtg aca gat gat agg gag      288
 Ile Glu Ala Asp Thr Leu Thr Ala Glu Lys Val Thr Asp Asp Arg Glu
                  85                  90                  95

 gaa gga gac aga aaa ccc aaa agc caa tgt cgt gta tta cag tac aac      336
 Glu Gly Asp Arg Lys Pro Lys Ser Gln Cys Arg Val Leu Gln Tyr Asn
             100                 105                 110

 gta agc atg gaa cct cat gat gac agt gaa tta tca gaa aag aac aaa      384
 Val Ser Met Glu Pro His Asp Asp Ser Glu Leu Ser Glu Lys Asn Lys
         115                 120                 125

 tta tat tgt ttt taa                                                  399
 Leu Tyr Cys Phe 
     130





      <210> 378
      <211> 294
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(294)

      <400> 378
  atg aag cgc ttc ctc ttc ctc cta ctc acc atc agc ctc ctg gtt atg      48
  Met Lys Arg Phe Leu Phe Leu Leu Leu Thr Ile Ser Leu Leu Val Met
    1               5                  10                  15

 gta cag aga agc ctg gat gtt cag gaa tgc aaa gaa gac agg act ctc       96
 Val Gln Arg Ser Leu Asp Val Gln Glu Cys Lys Glu Asp Arg Thr Leu
              20                  25                  30

 cca ttt cag aaa caa ctg gag tct caa aag cga ctg cta ttc cag gag      144
 Pro Phe Gln Lys Gln Leu Glu Ser Gln Lys Arg Leu Leu Phe Gln Glu
          35                  40                  45

 gca gct ttg gta gca tcc cag gtg ccc aga ggg gag tca gta cag cag      192
 Ala Ala Leu Val Ala Ser Gln Val Pro Arg Gly Glu Ser Val Gln Gln
      50                  55                  60

 acc gga gcc atc aag ttc ttg atc aag aac agc ttg atc acc atc aaa      240
 Thr Gly Ala Ile Lys Phe Leu Ile Lys Asn Ser Leu Ile Thr Ile Lys
  65                  70                  75                  80

 acc agc tta atc tcc atc aag aac agt tct agt tgc agc tcc atc aag      288
 Thr Ser Leu Ile Ser Ile Lys Asn Ser Ser Ser Cys Ser Ser Ile Lys
                  85                  90                  95

 cat taa                                                              294
 His 






      <210> 379
      <211> 561
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(561)

      <400> 379
  atg gac tgc agg gtc cac atg cga ccc atc ggc ctg acg tgg gtg ctg      48
  Met Asp Cys Arg Val His Met Arg Pro Ile Gly Leu Thr Trp Val Leu
    1               5                  10                  15

 caa ctg acc ttg gca tgg atc ctg cta gaa gcc tgt gga ggg agc cgc       96
 Gln Leu Thr Leu Ala Trp Ile Leu Leu Glu Ala Cys Gly Gly Ser Arg
              20                  25                  30

 cca ctc caa gcc agg tcc cag caa cac cat ggg ctg gca gct gat ctg      144
 Pro Leu Gln Ala Arg Ser Gln Gln His His Gly Leu Ala Ala Asp Leu
          35                  40                  45

 ggc aaa ggc aag ctg cac ctg gca gat gcg aat cct tcc tgg aac acc      192
 Gly Lys Gly Lys Leu His Leu Ala Asp Ala Asn Pro Ser Trp Asn Thr
      50                  55                  60

 tcc aac gtg ccc ttc gca gtc gct tcc gcc tgc ggc tat tgg ggg ttc      240
 Ser Asn Val Pro Phe Ala Val Ala Ser Ala Cys Gly Tyr Trp Gly Phe
  65                  70                  75                  80

 gcc aac tgc gaa gat gat atc acc tgc ggc ccg act tgg ctc cca ctc      288
 Ala Asn Cys Glu Asp Asp Ile Thr Cys Gly Pro Thr Trp Leu Pro Leu
                  85                  90                  95

 tca gaa aaa agg ggc tgt gag ccc agc tgc ctt acc tat gga cag acc      336
 Ser Glu Lys Arg Gly Cys Glu Pro Ser Cys Leu Thr Tyr Gly Gln Thr
             100                 105                 110

 ttc gca gac ggg acg gac ctt tgt cgc tcg gct ctg ggc cac gcc cta      384
 Phe Ala Asp Gly Thr Asp Leu Cys Arg Ser Ala Leu Gly His Ala Leu
         115                 120                 125

 ccg gtg gct gct cct gga gcc cgt cac tgc ttc aac atc tcc atc tcc      432
 Pro Val Ala Ala Pro Gly Ala Arg His Cys Phe Asn Ile Ser Ile Ser
     130                 135                 140

 gcg gta cct cgt ccc aga cca gga cga cgg ggc cgg gaa gct ccc tcc      480
 Ala Val Pro Arg Pro Arg Pro Gly Arg Arg Gly Arg Glu Ala Pro Ser
 145                 150                 155                 160

 cgg cgt tcc cgc agc cct cgc acc tcc atc ctg gac gct gcg ggc agc      528
 Arg Arg Ser Arg Ser Pro Arg Thr Ser Ile Leu Asp Ala Ala Gly Ser
                 165                 170                 175

 ggg agt ggc agt gga agc ggc agc ggc ccc tag                          561
 Gly Ser Gly Ser Gly Ser Gly Ser Gly Pro 
             180                 185





      <210> 380
      <211> 543
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(543)

      <400> 380
  atg gtt gca tct atg ata gcc atg gta cta gaa cta gta gta gtt cta      48
  Met Val Ala Ser Met Ile Ala Met Val Leu Glu Leu Val Val Val Leu
    1               5                  10                  15

 cta agt cca aat att agt cat ttt ggt aga gaa gct ctc caa ata ata       96
 Leu Ser Pro Asn Ile Ser His Phe Gly Arg Glu Ala Leu Gln Ile Ile
              20                  25                  30

 tcc ata att caa aga cca gtt aaa tcc tac agg cat att cac aga ata      144
 Ser Ile Ile Gln Arg Pro Val Lys Ser Tyr Arg His Ile His Arg Ile
          35                  40                  45

 act gcc ctg aaa aca ttg ctt aaa tta atg aag acc atc tat gga caa      192
 Thr Ala Leu Lys Thr Leu Leu Lys Leu Met Lys Thr Ile Tyr Gly Gln
      50                  55                  60

 tgc atc ttc aag agc tca aga tct ggt gaa aaa acg gaa aca aag aag      240
 Cys Ile Phe Lys Ser Ser Arg Ser Gly Glu Lys Thr Glu Thr Lys Lys
  65                  70                  75                  80

 aaa ttt caa tac aat gag ctg ggc tgc ttc gat cag agg ttc cat ggt      288
 Lys Phe Gln Tyr Asn Glu Leu Gly Cys Phe Asp Gln Arg Phe His Gly
                  85                  90                  95

 ctg aac tac tcc act ctg gtg aag gtt tct tcc cca aag cca ctc ctc      336
 Leu Asn Tyr Ser Thr Leu Val Lys Val Ser Ser Pro Lys Pro Leu Leu
             100                 105                 110

 aag ctg act tat att gta cct gag ttg cat gcc tgt gct cca aga gca      384
 Lys Leu Thr Tyr Ile Val Pro Glu Leu His Ala Cys Ala Pro Arg Ala
         115                 120                 125

 gac gtc ctt ccg cag gag cag gtc att aag agt cac tgc gtt gat cat      432
 Asp Val Leu Pro Gln Glu Gln Val Ile Lys Ser His Cys Val Asp His
     130                 135                 140

 gta gaa gag ctg ttt gaa tac cta cag gat gat ctc agg gtc caa gcc      480
 Val Glu Glu Leu Phe Glu Tyr Leu Gln Asp Asp Leu Arg Val Gln Ala
 145                 150                 155                 160

 ctg gtc aca cat gac tgt atg aaa ggc att cat ctg gcg gat gat agc      528
 Leu Val Thr His Asp Cys Met Lys Gly Ile His Leu Ala Asp Asp Ser
                 165                 170                 175

 ttc cag gcg gta tga                                                  543
 Phe Gln Ala Val 
             180





      <210> 381
      <211> 1032
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1032)

      <400> 381
  atg ctg gat gct ccc tgc cct caa aca ttg gac tcc aag ttc ttc ggc      48
  Met Leu Asp Ala Pro Cys Pro Gln Thr Leu Asp Ser Lys Phe Phe Gly
    1               5                  10                  15

 ttt tgg act ctt gga ttt aca cca gtg gtt tgc cag ggg ctc ttg agc       96
 Phe Trp Thr Leu Gly Phe Thr Pro Val Val Cys Gln Gly Leu Leu Ser
              20                  25                  30

 ctt tgg cca cag act aaa ggc tgc act gtc agc ttc cct act ttt gag      144
 Leu Trp Pro Gln Thr Lys Gly Cys Thr Val Ser Phe Pro Thr Phe Glu
          35                  40                  45

 gtt ttg gga ctc gga ctg gct tcc ctg ctc ttc agc ttg cag aca gcc      192
 Val Leu Gly Leu Gly Leu Ala Ser Leu Leu Phe Ser Leu Gln Thr Ala
      50                  55                  60

 tat tgt ggg gct tca act tcc gat tgt cct tta tgg gaa gta gca gca      240
 Tyr Cys Gly Ala Ser Thr Ser Asp Cys Pro Leu Trp Glu Val Ala Ala
  65                  70                  75                  80

 cca tcc agt tct cag aga gca agc tct gga gta act gag cta acc cgg      288
 Pro Ser Ser Ser Gln Arg Ala Ser Ser Gly Val Thr Glu Leu Thr Arg
                  85                  90                  95

 gtt acc cca gtg gat tta cag att gag gtt aga acc cag cag ggt tct      336
 Val Thr Pro Val Asp Leu Gln Ile Glu Val Arg Thr Gln Gln Gly Ser
             100                 105                 110

 ctt cct gga aag aat agc ctt ccc tct aag gtt tca aat aga ccc tgg      384
 Leu Pro Gly Lys Asn Ser Leu Pro Ser Lys Val Ser Asn Arg Pro Trp
         115                 120                 125

 ctt ggt cct aaa tgt gag aca att gtg aaa agt gga gga cag agc cac      432
 Leu Gly Pro Lys Cys Glu Thr Ile Val Lys Ser Gly Gly Gln Ser His
     130                 135                 140

 ctg gtt aaa tac agc ccc ggc ttt ctg ctt gaa tgt gag gca act gtg      480
 Leu Val Lys Tyr Ser Pro Gly Phe Leu Leu Glu Cys Glu Ala Thr Val
 145                 150                 155                 160

 aaa agt gca ggg cag agc cac ctg ggt aaa tac agc cct ggc ttt ctg      528
 Lys Ser Ala Gly Gln Ser His Leu Gly Lys Tyr Ser Pro Gly Phe Leu
                 165                 170                 175

 gtg aga gga ctg aaa cca gga tgt gtc aag gaa tcc tgc cta att tct      576
 Val Arg Gly Leu Lys Pro Gly Cys Val Lys Glu Ser Cys Leu Ile Ser
             180                 185                 190

 tcc gaa gtt cag ctg tct cag ttc aca cca aac aag tta cac gat ttc      624
 Ser Glu Val Gln Leu Ser Gln Phe Thr Pro Asn Lys Leu His Asp Phe
         195                 200                 205

 ata acg gat aga gga cag aag ctt aag gag gga ggg ccg aat gca ccg      672
 Ile Thr Asp Arg Gly Gln Lys Leu Lys Glu Gly Gly Pro Asn Ala Pro
     210                 215                 220

 gga acc cta gtc aag tgt agg aaa tca tca cga gcg agg cga agc agg      720
 Gly Thr Leu Val Lys Cys Arg Lys Ser Ser Arg Ala Arg Arg Ser Arg
 225                 230                 235                 240

 tcg tgg gag acg aga cct tca ctc agg aac ggg gac gat gtg aat cgt      768
 Ser Trp Glu Thr Arg Pro Ser Leu Arg Asn Gly Asp Asp Val Asn Arg
                 245                 250                 255

 gtt tct atc gag tgg ctg ggg gac cgg gtt ggg atc agc cag gag gag      816
 Val Ser Ile Glu Trp Leu Gly Asp Arg Val Gly Ile Ser Gln Glu Glu
             260                 265                 270

 gta gcc gca caa ggc tta gct ggg tct ccc gcg cag aca tct cct gga      864
 Val Ala Ala Gln Gly Leu Ala Gly Ser Pro Ala Gln Thr Ser Pro Gly
         275                 280                 285

 cag cga cgc agc gcc gcg cag gcg ctc act gcc cgg ctc cag ggc tgc      912
 Gln Arg Arg Ser Ala Ala Gln Ala Leu Thr Ala Arg Leu Gln Gly Cys
     290                 295                 300

 ggg tgg cga gtc cct gcc tgc ccg gcg ctc gcc ctc ggg gaa gga cgg      960
 Gly Trp Arg Val Pro Ala Cys Pro Ala Leu Ala Leu Gly Glu Gly Arg
 305                 310                 315                 320

 acg cct cgc gac ggc cgc gga cgc acc agc gca agt ggt tcc ttg gaa     1008
 Thr Pro Arg Asp Gly Arg Gly Arg Thr Ser Ala Ser Gly Ser Leu Glu
                 325                 330                 335

 tct ccc cca tgt aat tcc aca tga                                     1032
 Ser Pro Pro Cys Asn Ser Thr 
             340





      <210> 382
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 382
  atg cac ggc ggg atc agc cgt gcc gag tgc cac ctg gtc acc gta ctg      48
  Met His Gly Gly Ile Ser Arg Ala Glu Cys His Leu Val Thr Val Leu
    1               5                  10                  15

 cta ctg cca ctt acc aag aca gct cac acc cat cgt caa aac aag aag       96
 Leu Leu Pro Leu Thr Lys Thr Ala His Thr His Arg Gln Asn Lys Lys
              20                  25                  30

 gga gga gcg gcc ctc aag tgc tgt ccc ttt aat cca cac tgc aac tgc      144
 Gly Gly Ala Ala Leu Lys Cys Cys Pro Phe Asn Pro His Cys Asn Cys
          35                  40                  45

 aat tgt atg gca aag ctc tgt tta cca cgc aat gac acg tca gac agg      192
 Asn Cys Met Ala Lys Leu Cys Leu Pro Arg Asn Asp Thr Ser Asp Arg
      50                  55                  60

 ggt gag aag aca acg cat gct gca gat gaa gta ctc atc aca aag ttc      240
 Gly Glu Lys Thr Thr His Ala Ala Asp Glu Val Leu Ile Thr Lys Phe
  65                  70                  75                  80

 cca aat ccc tgg aag gca gca gtc aag tca aaa aaa tta aga agc tca      288
 Pro Asn Pro Trp Lys Ala Ala Val Lys Ser Lys Lys Leu Arg Ser Ser
                  85                  90                  95

 aca aat cca aat gag aaa aac gca aag agt tcc aca cct aca cac atc      336
 Thr Asn Pro Asn Glu Lys Asn Ala Lys Ser Ser Thr Pro Thr His Ile
             100                 105                 110

 acc atc agg ctg aaa cca cag aca gag act ctc aaa agc agc gac aga      384
 Thr Ile Arg Leu Lys Pro Gln Thr Glu Thr Leu Lys Ser Ser Asp Arg
         115                 120                 125

 gga gca acg tgt cat gaa cga ggg tcc tga                              414
 Gly Ala Thr Cys His Glu Arg Gly Ser 
     130                 135





      <210> 383
      <211> 651
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(651)

      <400> 383
  atg gag gcc gac acc ccc tcc ccc cgc aag ttt tat gac ctg tgg ata      48
  Met Glu Ala Asp Thr Pro Ser Pro Arg Lys Phe Tyr Asp Leu Trp Ile
    1               5                  10                  15

 agt tat gcg tcc aat gtc atc ttc tca gta agg gca ttt ctg ggc acc       96
 Ser Tyr Ala Ser Asn Val Ile Phe Ser Val Arg Ala Phe Leu Gly Thr
              20                  25                  30

 cta ttc acc atc gca cgc cct gca ccc act ctc ttc tcc act ctg ctt      144
 Leu Phe Thr Ile Ala Arg Pro Ala Pro Thr Leu Phe Ser Thr Leu Leu
          35                  40                  45

 tcc cct tta gct gtg gtc aca cca aat gta tta tgc att tta ttt ctt      192
 Ser Pro Leu Ala Val Val Thr Pro Asn Val Leu Cys Ile Leu Phe Leu
      50                  55                  60

 tat att gtc cac tgg ggt tct acc tat gag gat cca ggc cct gct gaa      240
 Tyr Ile Val His Trp Gly Ser Thr Tyr Glu Asp Pro Gly Pro Ala Glu
  65                  70                  75                  80

 agg gtt gac aat gaa gac tct cag gcc acc gta act cat gga gaa gcc      288
 Arg Val Asp Asn Glu Asp Ser Gln Ala Thr Val Thr His Gly Glu Ala
                  85                  90                  95

 ctg agc atc tgg ccc gct tgt aag cga agg aat gtg ctg gca tca ggg      336
 Leu Ser Ile Trp Pro Ala Cys Lys Arg Arg Asn Val Leu Ala Ser Gly
             100                 105                 110

 ctg ggt ggg att tca ttt tcc tcc tat caa gtt acc ctt agc cct ggt      384
 Leu Gly Gly Ile Ser Phe Ser Ser Tyr Gln Val Thr Leu Ser Pro Gly
         115                 120                 125

 atc gtg gag aag ttt gta gcc acg ggc atg cca tcc aac gga ggc agc      432
 Ile Val Glu Lys Phe Val Ala Thr Gly Met Pro Ser Asn Gly Gly Ser
     130                 135                 140

 ctc tac act tgt gcc ctg aaa aat cta aag caa aat aag tca ttt ggc      480
 Leu Tyr Thr Cys Ala Leu Lys Asn Leu Lys Gln Asn Lys Ser Phe Gly
 145                 150                 155                 160

 aaa tac atg tgg gtg cct gaa aca agc caa aag act tca gcg ttc aac      528
 Lys Tyr Met Trp Val Pro Glu Thr Ser Gln Lys Thr Ser Ala Phe Asn
                 165                 170                 175

 cct ctg gtg ctg ggc acc aat gag aag ctc atc tgg ccc cgg gat cct      576
 Pro Leu Val Leu Gly Thr Asn Glu Lys Leu Ile Trp Pro Arg Asp Pro
             180                 185                 190

 ggc agg aca ctg gga gca cta ttt cca tgg gca gca ggg ttg ttc ctg      624
 Gly Arg Thr Leu Gly Ala Leu Phe Pro Trp Ala Ala Gly Leu Phe Leu
         195                 200                 205

 gag aca tca ctg acc cag gac acc tag                                  651
 Glu Thr Ser Leu Thr Gln Asp Thr 
     210                 215





      <210> 384
      <211> 999
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(999)

      <400> 384
  atg ggg tta tta atg cat ctc acc ttc cga ata cca tgg cct agc cct      48
  Met Gly Leu Leu Met His Leu Thr Phe Arg Ile Pro Trp Pro Ser Pro
    1               5                  10                  15

 gtc tac ctt aac tgt gtc aga acc ctt acg tta cct gac agt tgg gca       96
 Val Tyr Leu Asn Cys Val Arg Thr Leu Thr Leu Pro Asp Ser Trp Ala
              20                  25                  30

 aaa tca gct aac aca aag aat atc cca tgt gat ttc ttg aac acc gta      144
 Lys Ser Ala Asn Thr Lys Asn Ile Pro Cys Asp Phe Leu Asn Thr Val
          35                  40                  45

 ttg aaa gtg aaa gaa aga act gct gca cgg ata gtg gaa gta cag tcc      192
 Leu Lys Val Lys Glu Arg Thr Ala Ala Arg Ile Val Glu Val Gln Ser
      50                  55                  60

 cga gtg aag cta ctg cac cac cat cga gtt cga gtg aag cta ccg cac      240
 Arg Val Lys Leu Leu His His His Arg Val Arg Val Lys Leu Pro His
  65                  70                  75                  80

 cac tcg atc aaa gtc gca tca agt cga gcg act atg aag ctg cgg acc      288
 His Ser Ile Lys Val Ala Ser Ser Arg Ala Thr Met Lys Leu Arg Thr
                  85                  90                  95

 gtc tgt gtg ccc ttt cca ttc att cct cag gtt cct gcc tct gtg tct      336
 Val Cys Val Pro Phe Pro Phe Ile Pro Gln Val Pro Ala Ser Val Ser
             100                 105                 110

 tct atg gac gca gct gct gtg aat gga gct tta ctc ttc ggt gaa cac      384
 Ser Met Asp Ala Ala Ala Val Asn Gly Ala Leu Leu Phe Gly Glu His
         115                 120                 125

 aga cca cga aca gta cct gtt ttg tct gtc aat aaa tac acc agg cgc      432
 Arg Pro Arg Thr Val Pro Val Leu Ser Val Asn Lys Tyr Thr Arg Arg
     130                 135                 140

 cca agt tcc tct ggg ata gtg ctg gtc cga acg acc gtg cca ggg atg      480
 Pro Ser Ser Ser Gly Ile Val Leu Val Arg Thr Thr Val Pro Gly Met
 145                 150                 155                 160

 ttc tca tct ttc atc atc atc cat cca tac acc gct ttg ccc atg tcc      528
 Phe Ser Ser Phe Ile Ile Ile His Pro Tyr Thr Ala Leu Pro Met Ser
                 165                 170                 175

 aag ttc aca cgc aaa ctg cca aat aaa acc cat tgc agt gct aca aaa      576
 Lys Phe Thr Arg Lys Leu Pro Asn Lys Thr His Cys Ser Ala Thr Lys
             180                 185                 190

 gtg tct gag gag gat tca gtg gag aga gct cag gga gag gag cgt atc      624
 Val Ser Glu Glu Asp Ser Val Glu Arg Ala Gln Gly Glu Glu Arg Ile
         195                 200                 205

 cgt gca gga ttc agt gga gag agc tca ggg aga gaa gcg tat ccg tgc      672
 Arg Ala Gly Phe Ser Gly Glu Ser Ser Gly Arg Glu Ala Tyr Pro Cys
     210                 215                 220

 agg att cag tgg aga gag ctc agg gac agg agc gta tcc gtg cag gat      720
 Arg Ile Gln Trp Arg Glu Leu Arg Asp Arg Ser Val Ser Val Gln Asp
 225                 230                 235                 240

 tca gtg gag aca gct cag gga gag aag cgt atc cgt gca gga ttc agt      768
 Ser Val Glu Thr Ala Gln Gly Glu Lys Arg Ile Arg Ala Gly Phe Ser
                 245                 250                 255

 gga gag agc tca ggg aca gga gcg tat ccg tgc agg att cag gga agg      816
 Gly Glu Ser Ser Gly Thr Gly Ala Tyr Pro Cys Arg Ile Gln Gly Arg
             260                 265                 270

 ctc cgg agt gca gat gtg cac cag gca cat cat aca tac atg cat acg      864
 Leu Arg Ser Ala Asp Val His Gln Ala His His Thr Tyr Met His Thr
         275                 280                 285

 gtg cat cag gca tgc aca gac aca cag ctt aca cat gct gtg ccg ctg      912
 Val His Gln Ala Cys Thr Asp Thr Gln Leu Thr His Ala Val Pro Leu
     290                 295                 300

 gaa caa agg cag aga tac acc cta aac atg gaa gca tgc tat ttg atc      960
 Glu Gln Arg Gln Arg Tyr Thr Leu Asn Met Glu Ala Cys Tyr Leu Ile
 305                 310                 315                 320

 tgc atc cat tgc aca aga tgt aag gac aaa caa atg tag                  999
 Cys Ile His Cys Thr Arg Cys Lys Asp Lys Gln Met 
                 325                 330





      <210> 385
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 385
  atg cag cag aag cga aag aaa cct tct caa ggg ctt gtg gga ctc tca      48
  Met Gln Gln Lys Arg Lys Lys Pro Ser Gln Gly Leu Val Gly Leu Ser
    1               5                  10                  15

 gga ggg ctg ctg ctg gtc tgg tta cta ctt act gct gcc agt ggc tat       96
 Gly Gly Leu Leu Leu Val Trp Leu Leu Leu Thr Ala Ala Ser Gly Tyr
              20                  25                  30

 ggc cgg ctg ggc cac gca gag cag gat gag atg gtc ccc cac ctg gtg      144
 Gly Arg Leu Gly His Ala Glu Gln Asp Glu Met Val Pro His Leu Val
          35                  40                  45

 aag ctg ttt gac ttc cct gga cat cgg gtg tcc cag atc tat act ggt      192
 Lys Leu Phe Asp Phe Pro Gly His Arg Val Ser Gln Ile Tyr Thr Gly
      50                  55                  60

 tac acc tgc tcc ttt gcc atc agt gaa gtg ggt ggt ctg ttt ttc cag      240
 Tyr Thr Cys Ser Phe Ala Ile Ser Glu Val Gly Gly Leu Phe Phe Gln
  65                  70                  75                  80

 ggg gcc acc aac acc tcc cgt gaa tct acc aca tac cca aaa gca gtg      288
 Gly Ala Thr Asn Thr Ser Arg Glu Ser Thr Thr Tyr Pro Lys Ala Val
                  85                  90                  95

 cag gac ctc tgt ggc tgg ata atc cag agc ctg gct tgt ggg aag agc      336
 Gln Asp Leu Cys Gly Trp Ile Ile Gln Ser Leu Ala Cys Gly Lys Ser
             100                 105                 110

 agc atc att gtg gcc acc gag aga gca cca tag                          369
 Ser Ile Ile Val Ala Thr Glu Arg Ala Pro 
         115                 120





      <210> 386
      <211> 363
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(363)

      <400> 386
  atg aac agg ctt agg ccg agg gct ctc aga tgt att tac ctc tgt gcc      48
  Met Asn Arg Leu Arg Pro Arg Ala Leu Arg Cys Ile Tyr Leu Cys Ala
    1               5                  10                  15

 tgg cag ctg gcc cgt ggt gac agg cag agc tgg agg ctg gcc atc ttg       96
 Trp Gln Leu Ala Arg Gly Asp Arg Gln Ser Trp Arg Leu Ala Ile Leu
              20                  25                  30

 gaa ggc ggc cga agg ccc atg tgt cct ctt ggc ctc tgg ccc cgg agg      144
 Glu Gly Gly Arg Arg Pro Met Cys Pro Leu Gly Leu Trp Pro Arg Arg
          35                  40                  45

 gcg gat ggg gat gtg gaa gtt gct gac aga gca ttt tct gag ctg ttg      192
 Ala Asp Gly Asp Val Glu Val Ala Asp Arg Ala Phe Ser Glu Leu Leu
      50                  55                  60

 gct aag agg ccg gtg tca cca tac agc ggg tac aat ggg cag ctg ctg      240
 Ala Lys Arg Pro Val Ser Pro Tyr Ser Gly Tyr Asn Gly Gln Leu Leu
  65                  70                  75                  80

 acc agt gtg tac cag ccc act gag atg gcc ctg atg cac aaa gtt ccg      288
 Thr Ser Val Tyr Gln Pro Thr Glu Met Ala Leu Met His Lys Val Pro
                  85                  90                  95

 agc agt gag gga atg gag tca aac tgg agg caa aga gac cac gca gtg      336
 Ser Ser Glu Gly Met Glu Ser Asn Trp Arg Gln Arg Asp His Ala Val
             100                 105                 110

 tac gtg gtc atc cag atg aga aac tga                                  363
 Tyr Val Val Ile Gln Met Arg Asn 
         115                 120





      <210> 387
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 387
  atg gcg ctg cgg cac ctc gcc ctc ctg gct ggc ctt ctc gtg gga gtc      48
  Met Ala Leu Arg His Leu Ala Leu Leu Ala Gly Leu Leu Val Gly Val
    1               5                  10                  15

 gcc agc aag tcc atg gag aac acg gac act gat gtc cca gcc cca gag       96
 Ala Ser Lys Ser Met Glu Asn Thr Asp Thr Asp Val Pro Ala Pro Glu
              20                  25                  30

 gtg ctg acc agg tcc act gct ggg gtc aga ggg gcc tgt gcc tcg cag      144
 Val Leu Thr Arg Ser Thr Ala Gly Val Arg Gly Ala Cys Ala Ser Gln
          35                  40                  45

 agg gga gcc ctc cgc tgc ctg ctg ggt gag cgc ctg ctc agg aat ggc      192
 Arg Gly Ala Leu Arg Cys Leu Leu Gly Glu Arg Leu Leu Arg Asn Gly
      50                  55                  60

 tgg gtc agg cgg ggc ccc cac ggc cca cag ggg aca gag ggc cac ccg      240
 Trp Val Arg Arg Gly Pro His Gly Pro Gln Gly Thr Glu Gly His Pro
  65                  70                  75                  80

 atg ctg act cca gaa gag gcc gga gct gcg gac att gag atg tgc tcc      288
 Met Leu Thr Pro Glu Glu Ala Gly Ala Ala Asp Ile Glu Met Cys Ser
                  85                  90                  95

 cac ggc acc cct cag ccg ctg ctg ctc tgg gcg tga                      324
 His Gly Thr Pro Gln Pro Leu Leu Leu Trp Ala 
             100                 105





      <210> 388
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 388
  atg atg cct acg cca ctt ctc atg ttg cta cct gtt gct acc acc ggg      48
  Met Met Pro Thr Pro Leu Leu Met Leu Leu Pro Val Ala Thr Thr Gly
    1               5                  10                  15

 cat cgc tgc cgc ctc ctg ctc tgt gca cag tgt gat gaa att gaa atg       96
 His Arg Cys Arg Leu Leu Leu Cys Ala Gln Cys Asp Glu Ile Glu Met
              20                  25                  30

 gcc aat gag cac acc ctc att cat cca gcg agc att gag gac ccc cta      144
 Ala Asn Glu His Thr Leu Ile His Pro Ala Ser Ile Glu Asp Pro Leu
          35                  40                  45

 gag gcc agg ccc atg agt gat gaa gat ccc gag gat gaa gac gcc ttg      192
 Glu Ala Arg Pro Met Ser Asp Glu Asp Pro Glu Asp Glu Asp Ala Leu
      50                  55                  60

 cca gcc agg agt tat aaa aca aac aga aaa gga aga atc tgc aac aga      240
 Pro Ala Arg Ser Tyr Lys Thr Asn Arg Lys Gly Arg Ile Cys Asn Arg
  65                  70                  75                  80

 gac cat aag tgg tct gca aag cca aag gtt tat aga aat ggg cag acc      288
 Asp His Lys Trp Ser Ala Lys Pro Lys Val Tyr Arg Asn Gly Gln Thr
                  85                  90                  95

 tgc tct aag ggg cct gct tgc tga                                      312
 Cys Ser Lys Gly Pro Ala Cys 
             100





      <210> 389
      <211> 429
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(429)

      <400> 389
  atg gct tcc ctg tcc aca tcc ctg tcc atc cgc ata ctc cga atc ccc      48
  Met Ala Ser Leu Ser Thr Ser Leu Ser Ile Arg Ile Leu Arg Ile Pro
    1               5                  10                  15

 ttc ctt cct ttg ctg ccg tct cta ctc tcc cag aag cca gtc tat act       96
 Phe Leu Pro Leu Leu Pro Ser Leu Leu Ser Gln Lys Pro Val Tyr Thr
              20                  25                  30

 gcc tgc ctt ctg cgc tcc aag gcc aaa ccc tgg ggt tgg ggc caa cag      144
 Ala Cys Leu Leu Arg Ser Lys Ala Lys Pro Trp Gly Trp Gly Gln Gln
          35                  40                  45

 gct ttc aac agg gca gac ccc agc ctg agc att ccc aac ctt gtg gtc      192
 Ala Phe Asn Arg Ala Asp Pro Ser Leu Ser Ile Pro Asn Leu Val Val
      50                  55                  60

 agg agg ggc tct gtg gaa ggc tcc aga gcc tcc tgg ggt gga gct ttc      240
 Arg Arg Gly Ser Val Glu Gly Ser Arg Ala Ser Trp Gly Gly Ala Phe
  65                  70                  75                  80

 atc atg tgt tcc aaa ctg ggc agg tcc atc ctg ctg gag gag gcc atg      288
 Ile Met Cys Ser Lys Leu Gly Arg Ser Ile Leu Leu Glu Glu Ala Met
                  85                  90                  95

 gcc agg gaa gat gca aag ccc cat gtt gga gtg gac gga ctc tat ctt      336
 Ala Arg Glu Asp Ala Lys Pro His Val Gly Val Asp Gly Leu Tyr Leu
             100                 105                 110

 gca tac cag ctg cat ggg ttc ttc aaa gtc aga ctc ctc gtt cga gtt      384
 Ala Tyr Gln Leu His Gly Phe Phe Lys Val Arg Leu Leu Val Arg Val
         115                 120                 125

 ggc ttc cgt gtc cag ctc agc ttc aag ctt gag ggc tgg gta tag          429
 Gly Phe Arg Val Gln Leu Ser Phe Lys Leu Glu Gly Trp Val 
     130                 135                 140





      <210> 390
      <211> 234
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(234)

      <400> 390
  atg cag ttc atg agt tac aag tct tcc caa att cac tgg ctg agt act      48
  Met Gln Phe Met Ser Tyr Lys Ser Ser Gln Ile His Trp Leu Ser Thr
    1               5                  10                  15

 ttg gat gca ctc acg ttc ctg gtg tct gcg ttt cct tgc tgt tct atg       96
 Leu Asp Ala Leu Thr Phe Leu Val Ser Ala Phe Pro Cys Cys Ser Met
              20                  25                  30

 gta act gac aga gaa tta atc aag aga aaa aca aag ggc aca ctg aat      144
 Val Thr Asp Arg Glu Leu Ile Lys Arg Lys Thr Lys Gly Thr Leu Asn
          35                  40                  45

 tct gaa tat gtg tgt gca gac acc gga ata tac aga aag gaa acg tac      192
 Ser Glu Tyr Val Cys Ala Asp Thr Gly Ile Tyr Arg Lys Glu Thr Tyr
      50                  55                  60

 caa aat atg aat cct gat tat ctc tgg gat aag tgt tta tga              234
 Gln Asn Met Asn Pro Asp Tyr Leu Trp Asp Lys Cys Leu 
  65                  70                  75





      <210> 391
      <211> 195
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(195)

      <400> 391
  atg aaa tct atg ttg aaa ctc ttt tta gta gga tta att gat ctt ccc      48
  Met Lys Ser Met Leu Lys Leu Phe Leu Val Gly Leu Ile Asp Leu Pro
    1               5                  10                  15

 cta aaa gtc ctg cag cag agg tcc aca ttc ttt atg gtc tca gga tcc       96
 Leu Lys Val Leu Gln Gln Arg Ser Thr Phe Phe Met Val Ser Gly Ser
              20                  25                  30

 cca gca gaa atc cat tct cat tcc cga ata gga aat aag gcc ata cgc      144
 Pro Ala Glu Ile His Ser His Ser Arg Ile Gly Asn Lys Ala Ile Arg
          35                  40                  45

 tca gag ttt cct ctc ctg aac gag acg cta gca agc tca gaa cat gag      192
 Ser Glu Phe Pro Leu Leu Asn Glu Thr Leu Ala Ser Ser Glu His Glu
      50                  55                  60

 taa                                                                  195
 






      <210> 392
      <211> 480
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(480)

      <400> 392
  atg gcg ctg gca tct gct ctg ctt ctg atc aca ttc cag ttc ata gca      48
  Met Ala Leu Ala Ser Ala Leu Leu Leu Ile Thr Phe Gln Phe Ile Ala
    1               5                  10                  15

 aca ttt tct act ctg gtg cct tta gta gat tgt tca tct gta cta caa       96
 Thr Phe Ser Thr Leu Val Pro Leu Val Asp Cys Ser Ser Val Leu Gln
              20                  25                  30

 gaa aga aat gac ctc aca gaa gtg gcc ctt cag aag gtt ttt aat ttt      144
 Glu Arg Asn Asp Leu Thr Glu Val Ala Leu Gln Lys Val Phe Asn Phe
          35                  40                  45

 tct act tca cat ata ttt gaa aca aga gta gca ggt cgc atg gtg gca      192
 Ser Thr Ser His Ile Phe Glu Thr Arg Val Ala Gly Arg Met Val Ala
      50                  55                  60

 gac atg tgc cgc gct gct gta aag aaa gtt act aga cgc caa cgg aga      240
 Asp Met Cys Arg Ala Ala Val Lys Lys Val Thr Arg Arg Gln Arg Arg
  65                  70                  75                  80

 tgc gaa gag gcg ggg atc gta ggg gaa gga aga acc gga gga agc aag      288
 Cys Glu Glu Ala Gly Ile Val Gly Glu Gly Arg Thr Gly Gly Ser Lys
                  85                  90                  95

 gag aca agt caa gga act ccc cca aag aca aat tct ctt tgc ccc gcc      336
 Glu Thr Ser Gln Gly Thr Pro Pro Lys Thr Asn Ser Leu Cys Pro Ala
             100                 105                 110

 tct ccc atg cgc aaa agt cca cgg agg acc ctt gag aaa ggc tca cct      384
 Ser Pro Met Arg Lys Ser Pro Arg Arg Thr Leu Glu Lys Gly Ser Pro
         115                 120                 125

 ctc tcc ctc ggg gcc ggg gct ctg gct acc cag ggc ccc cca ggt ggg      432
 Leu Ser Leu Gly Ala Gly Ala Leu Ala Thr Gln Gly Pro Pro Gly Gly
     130                 135                 140

 aag aca aca acc cga aca ctt cgg gag aag cag atg cgg agg acg tag      480
 Lys Thr Thr Thr Arg Thr Leu Arg Glu Lys Gln Met Arg Arg Thr 
 145                 150                 155





      <210> 393
      <211> 963
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(963)

      <400> 393
  atg aag aac tca ctg ctc cag ctg aga ttg gtc agg ttg atc cag gcc      48
  Met Lys Asn Ser Leu Leu Gln Leu Arg Leu Val Arg Leu Ile Gln Ala
    1               5                  10                  15

 aac ttg tct gtc ctg cga cct ggc tca gcc atg agc ccc agg ccc ccc       96
 Asn Leu Ser Val Leu Arg Pro Gly Ser Ala Met Ser Pro Arg Pro Pro
              20                  25                  30

 cac cag cct gtg tcc ctg gag cct gca gct gag ttg atg tgg caa atc      144
 His Gln Pro Val Ser Leu Glu Pro Ala Ala Glu Leu Met Trp Gln Ile
          35                  40                  45

 agg gca ttt caa gaa ttt ctc aga cag cat gag gaa gct acc tca acc      192
 Arg Ala Phe Gln Glu Phe Leu Arg Gln His Glu Glu Ala Thr Ser Thr
      50                  55                  60

 ctg tcc aat ctg cag tgg gga cca ctg gag ggt gga ctg ttc ctg ggc      240
 Leu Ser Asn Leu Gln Trp Gly Pro Leu Glu Gly Gly Leu Phe Leu Gly
  65                  70                  75                  80

 atg ctg gtc acc agg tcc aga gcc agt ctt cca aat ggt cca gca gca      288
 Met Leu Val Thr Arg Ser Arg Ala Ser Leu Pro Asn Gly Pro Ala Ala
                  85                  90                  95

 gga ctg aca ggt ccc agg gct cct ctc ctg gct cct gta gtc cag acc      336
 Gly Leu Thr Gly Pro Arg Ala Pro Leu Leu Ala Pro Val Val Gln Thr
             100                 105                 110

 acc att atc atc aag gtg ccc tgg gta atc atg gaa atc gaa gag agg      384
 Thr Ile Ile Ile Lys Val Pro Trp Val Ile Met Glu Ile Glu Glu Arg
         115                 120                 125

 aaa gtg gac ctc ctt ttg gac act ggg act ggt ctc tca gtt ctc ctc      432
 Lys Val Asp Leu Leu Leu Asp Thr Gly Thr Gly Leu Ser Val Leu Leu
     130                 135                 140

 ttg aat cca ggc ccc ctc tcc tct ctt agc atg act tgt ctt ctc caa      480
 Leu Asn Pro Gly Pro Leu Ser Ser Leu Ser Met Thr Cys Leu Leu Gln
 145                 150                 155                 160

 ggc tac cta ggg gaa gac tgg caa atg gat ttc acc cat atg cca aag      528
 Gly Tyr Leu Gly Glu Asp Trp Gln Met Asp Phe Thr His Met Pro Lys
                 165                 170                 175

 gaa ctg aaa caa ctg ttg aag gcc caa tcc cac gaa cca ggc cca cct      576
 Glu Leu Lys Gln Leu Leu Lys Ala Gln Ser His Glu Pro Gly Pro Pro
             180                 185                 190

 cta ttc aac cca ggg gac cta gta ctg gta aag ggg ttt gag cag tgg      624
 Leu Phe Asn Pro Gly Asp Leu Val Leu Val Lys Gly Phe Glu Gln Trp
         195                 200                 205

 ggc aac caa aca gcc ctc agt ctt cag ggc tcc ata ccg gca gtg gga      672
 Gly Asn Gln Thr Ala Leu Ser Leu Gln Gly Ser Ile Pro Ala Val Gly
     210                 215                 220

 gag aag gtc ttc ttc aca aac agg cag ttg gtc tat tta gat gcc att      720
 Glu Lys Val Phe Phe Thr Asn Arg Gln Leu Val Tyr Leu Asp Ala Ile
 225                 230                 235                 240

 agt gag gca tgt gcc aga gca ggc agc tgc att gct gtc cct agg agt      768
 Ser Glu Ala Cys Ala Arg Ala Gly Ser Cys Ile Ala Val Pro Arg Ser
                 245                 250                 255

 cca gag gaa aac gag gcc att gca aga ttt ttg aag aag tac aac atg      816
 Pro Glu Glu Asn Glu Ala Ile Ala Arg Phe Leu Lys Lys Tyr Asn Met
             260                 265                 270

 tat gcc tac atg gcc ctg gcc aag ggt ccc agc cct gga gac ttc tgc      864
 Tyr Ala Tyr Met Ala Leu Ala Lys Gly Pro Ser Pro Gly Asp Phe Cys
         275                 280                 285

 tac cta gat gag gcc cct gtg gac tac acg aac cgg tgc cca ggg gag      912
 Tyr Leu Asp Glu Ala Pro Val Asp Tyr Thr Asn Arg Cys Pro Gly Glu
     290                 295                 300

 ctc ata ggt cag ggc aat gag aag tgc ttg gag atg tac aca gtg gaa      960
 Leu Ile Gly Gln Gly Asn Glu Lys Cys Leu Glu Met Tyr Thr Val Glu
 305                 310                 315                 320

 tga                                                                  963
 






      <210> 394
      <211> 342
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(342)

      <400> 394
  atg ggg ctg ctg ggg cag gat ctc ttt gtc acc tcc ttt ctg tgt cca      48
  Met Gly Leu Leu Gly Gln Asp Leu Phe Val Thr Ser Phe Leu Cys Pro
    1               5                  10                  15

 acc tgg ccg tcc cca tca ggc gcc cac ggc ctg cga gag gag ccc gag       96
 Thr Trp Pro Ser Pro Ser Gly Ala His Gly Leu Arg Glu Glu Pro Glu
              20                  25                  30

 ttt gtg acg gca aga gct ggg gag agc gtg gtc ctg cga tgc gac gtg      144
 Phe Val Thr Ala Arg Ala Gly Glu Ser Val Val Leu Arg Cys Asp Val
          35                  40                  45

 atc cac cca gtg acg gga cag ccc cca ccc tat gtc gta gag tgg ttc      192
 Ile His Pro Val Thr Gly Gln Pro Pro Pro Tyr Val Val Glu Trp Phe
      50                  55                  60

 aag ttc ggg gtc ccc atc cct atc ttc atc aag ttt ggc tac tac ccg      240
 Lys Phe Gly Val Pro Ile Pro Ile Phe Ile Lys Phe Gly Tyr Tyr Pro
  65                  70                  75                  80

 ccg cac gtg gac cct gag tat gca gat gtt gct ctg atg cca acc cat      288
 Pro His Val Asp Pro Glu Tyr Ala Asp Val Ala Leu Met Pro Thr His
                  85                  90                  95

 tct gtt ctc agc ttc tgg cct gct gcc tat ctc ctg ggt cac tgg ctt      336
 Ser Val Leu Ser Phe Trp Pro Ala Ala Tyr Leu Leu Gly His Trp Leu
             100                 105                 110

 tgg tag                                                              342
 Trp 






      <210> 395
      <211> 1269
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1269)

      <400> 395
  atg tgt ctg aga gcc aga gga ggg gcc ctg gca ctg ctc aca gcc act      48
  Met Cys Leu Arg Ala Arg Gly Gly Ala Leu Ala Leu Leu Thr Ala Thr
    1               5                  10                  15

 ggc ctg ctc ctg agg cgc cct gag ctg aca agg ccc gag tgt agg ctg       96
 Gly Leu Leu Leu Arg Arg Pro Glu Leu Thr Arg Pro Glu Cys Arg Leu
              20                  25                  30

 cgg gcg ggc gct gca tcc tgg tgg ctc atg gcg gtc ccc ttt ctg ttt      144
 Arg Ala Gly Ala Ala Ser Trp Trp Leu Met Ala Val Pro Phe Leu Phe
          35                  40                  45

 gca agc ctc ggt ccg gaa gaa gaa ggc gtg tcc tgt gtt tct tcc ctg      192
 Ala Ser Leu Gly Pro Glu Glu Glu Gly Val Ser Cys Val Ser Ser Leu
      50                  55                  60

 acc tgt gtt cac atc gtc atg acc gtg aag ctg gcc gga ccc ctg ttt      240
 Thr Cys Val His Ile Val Met Thr Val Lys Leu Ala Gly Pro Leu Phe
  65                  70                  75                  80

 ggt ctc agc tgg ggc tgc ctg gat ggg ggg ttg cag atg agc aga gcc      288
 Gly Leu Ser Trp Gly Cys Leu Asp Gly Gly Leu Gln Met Ser Arg Ala
                  85                  90                  95

 tct ggc tgc att cct gac cct cag gac ccc ttt gtg gtg ggc agg aac      336
 Ser Gly Cys Ile Pro Asp Pro Gln Asp Pro Phe Val Val Gly Arg Asn
             100                 105                 110

 tgc ctc cct tta agg ccc gga aat cac cca ttc ccc aag agg ctg ccc      384
 Cys Leu Pro Leu Arg Pro Gly Asn His Pro Phe Pro Lys Arg Leu Pro
         115                 120                 125

 tgt gcc ctg tgg ggc act aga agg aga agg gag cag tgt gag ccc ttt      432
 Cys Ala Leu Trp Gly Thr Arg Arg Arg Arg Glu Gln Cys Glu Pro Phe
     130                 135                 140

 ggc tac acc tcc cca ccc agg gct ggt gtg gag tgg gag act ggc agt      480
 Gly Tyr Thr Ser Pro Pro Arg Ala Gly Val Glu Trp Glu Thr Gly Ser
 145                 150                 155                 160

 cac tgt ggc tgt ggg cag ccg gac cgc agg ccc cag ata gac tca ggt      528
 His Cys Gly Cys Gly Gln Pro Asp Arg Arg Pro Gln Ile Asp Ser Gly
                 165                 170                 175

 tcc ccc ttt cac agc agc aag cac atc ggg ggc ggc tct ctg cag cag      576
 Ser Pro Phe His Ser Ser Lys His Ile Gly Gly Gly Ser Leu Gln Gln
             180                 185                 190

 cca cgg gct tgc acc aga tac tac agc tgc cag aaa act ccc agc ggg      624
 Pro Arg Ala Cys Thr Arg Tyr Tyr Ser Cys Gln Lys Thr Pro Ser Gly
         195                 200                 205

 ctt tct agg ccc cac tgc tgc gcc gag gat gtg gtg gac acc cgg gaa      672
 Leu Ser Arg Pro His Cys Cys Ala Glu Asp Val Val Asp Thr Arg Glu
     210                 215                 220

 ggt tct gaa gag tca aca ggc aaa cag ctg ggc act ctg ccc ctc aat      720
 Gly Ser Glu Glu Ser Thr Gly Lys Gln Leu Gly Thr Leu Pro Leu Asn
 225                 230                 235                 240

 ggg gct ggc tcc cag gct ctg ggc cta ttg tgt ggc cac agg caa agg      768
 Gly Ala Gly Ser Gln Ala Leu Gly Leu Leu Cys Gly His Arg Gln Arg
                 245                 250                 255

 aac tcg ctg gac agt gga cct agt gtc act tca gtg cag agc cta ttt      816
 Asn Ser Leu Asp Ser Gly Pro Ser Val Thr Ser Val Gln Ser Leu Phe
             260                 265                 270

 tcc agg aga ctc agc cac cag tcc acc cgt att tcc caa gca cct gcc      864
 Ser Arg Arg Leu Ser His Gln Ser Thr Arg Ile Ser Gln Ala Pro Ala
         275                 280                 285

 atg ggc cac gtc ctc gcc aag ggt gct gta ggg gca cag cct ttg gtg      912
 Met Gly His Val Leu Ala Lys Gly Ala Val Gly Ala Gln Pro Leu Val
     290                 295                 300

 tgc atc tgg cag tgt gga gac aca cac gag aag ttt cca agc acc tct      960
 Cys Ile Trp Gln Cys Gly Asp Thr His Glu Lys Phe Pro Ser Thr Ser
 305                 310                 315                 320

 gtt cat aac agc aag acg ctg gaa atg atg caa gtg cct gtg aac aag     1008
 Val His Asn Ser Lys Thr Leu Glu Met Met Gln Val Pro Val Asn Lys
                 325                 330                 335

 aaa gga tcc gga tgc cct gta cct ggc gag aga tgc agc tgc tat cag     1056
 Lys Gly Ser Gly Cys Pro Val Pro Gly Glu Arg Cys Ser Cys Tyr Gln
             340                 345                 350

 tcc tca gcc gtg gcc tgg ttc ctg tcc tgg ggg ctg acc agc ctt ctg     1104
 Ser Ser Ala Val Ala Trp Phe Leu Ser Trp Gly Leu Thr Ser Leu Leu
         355                 360                 365

 ggg cct ggg acc tgg ggc atc gct gct gcc tgc cgt ctg gcc tca ggg     1152
 Gly Pro Gly Thr Trp Gly Ile Ala Ala Ala Cys Arg Leu Ala Ser Gly
     370                 375                 380

 cac ctg caa ggc cgg aac ctg ctg gac gtc cgt gtg tcc cac tcc atc     1200
 His Leu Gln Gly Arg Asn Leu Leu Asp Val Arg Val Ser His Ser Ile
 385                 390                 395                 400

 agg cct gga gac ccg gga ggc cag cag cag agc cac act cta ttc tgt     1248
 Arg Pro Gly Asp Pro Gly Gly Gln Gln Gln Ser His Thr Leu Phe Cys
                 405                 410                 415

 gtc ctc atc acc aag cac tag                                         1269
 Val Leu Ile Thr Lys His 
             420





      <210> 396
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 396
  atg ccc ttg gtg atg cct ccc ctg gca gcc gct cct ctg ctc aca tgg      48
  Met Pro Leu Val Met Pro Pro Leu Ala Ala Ala Pro Leu Leu Thr Trp
    1               5                  10                  15

 cag cgg cac aca gtg ggc acg tgg gac aag tcg ggc acc agc gag ggc       96
 Gln Arg His Thr Val Gly Thr Trp Asp Lys Ser Gly Thr Ser Glu Gly
              20                  25                  30

 tcg gca tct ccc cct tcc cac gcc aca ggc tgg atc act gca cca aag      144
 Ser Ala Ser Pro Pro Ser His Ala Thr Gly Trp Ile Thr Ala Pro Lys
          35                  40                  45

 ggt ttg ggc tcc aga aag agc aga cta aac cca ggc ttc ttc ctg cag      192
 Gly Leu Gly Ser Arg Lys Ser Arg Leu Asn Pro Gly Phe Phe Leu Gln
      50                  55                  60

 aag ccg cac cac tgc agc tgc gcc aac ctg gtc gtg cag ccg gca ttt      240
 Lys Pro His His Cys Ser Cys Ala Asn Leu Val Val Gln Pro Ala Phe
  65                  70                  75                  80

 tag                                                                  243
 






      <210> 397
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 397
  atg tcc cca gta tct ctc tgc aga ctc ctg tgt gcc ctc aaa agt cta      48
  Met Ser Pro Val Ser Leu Cys Arg Leu Leu Cys Ala Leu Lys Ser Leu
    1               5                  10                  15

 cac ggt acc agt caa gag aca tcc ata ctg caa gat gat aga aag ttc       96
 His Gly Thr Ser Gln Glu Thr Ser Ile Leu Gln Asp Asp Arg Lys Phe
              20                  25                  30

 tgc caa ctc tac ccc ctg ccc aaa ttt ccc caa att gct cag ctc agt      144
 Cys Gln Leu Tyr Pro Leu Pro Lys Phe Pro Gln Ile Ala Gln Leu Ser
          35                  40                  45

 tgt gat ctg gtc att gtc att ccc tcc aag aga agg gga tgc atc ttc      192
 Cys Asp Leu Val Ile Val Ile Pro Ser Lys Arg Arg Gly Cys Ile Phe
      50                  55                  60

 ttt aag agt gcg gca agc aag gcg tgg gca gga ggg acg ctg gcc cag      240
 Phe Lys Ser Ala Ala Ser Lys Ala Trp Ala Gly Gly Thr Leu Ala Gln
  65                  70                  75                  80

 tta cct ggc gag tct gtg gct cag agc ctg gtg ctg cgt cag gtt gtc      288
 Leu Pro Gly Glu Ser Val Ala Gln Ser Leu Val Leu Arg Gln Val Val
                  85                  90                  95

 acc aag acc agg gat caa cca gaa agg gct gga gtg gaa ata gag ccc      336
 Thr Lys Thr Arg Asp Gln Pro Glu Arg Ala Gly Val Glu Ile Glu Pro
             100                 105                 110

 cag gag cca ccc aga cta agg ttg ccg aca atc tgt gag act gag ttc      384
 Gln Glu Pro Pro Arg Leu Arg Leu Pro Thr Ile Cys Glu Thr Glu Phe
         115                 120                 125

 aat tca gtg gtc ata acc aac att tat ttc aac agg atg aca ctg aat      432
 Asn Ser Val Val Ile Thr Asn Ile Tyr Phe Asn Arg Met Thr Leu Asn
     130                 135                 140

 gaa ata gaa tag                                                      444
 Glu Ile Glu 
 145





      <210> 398
      <211> 459
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(459)

      <400> 398
  atg ccc agg gca acc tcc tct cca tca cgg gtt ctg cta gga tgt gct      48
  Met Pro Arg Ala Thr Ser Ser Pro Ser Arg Val Leu Leu Gly Cys Ala
    1               5                  10                  15

 ctt ctc aca gcg atg gct gca ggg caa gag ggc aag gct gca gct gga       96
 Leu Leu Thr Ala Met Ala Ala Gly Gln Glu Gly Lys Ala Ala Ala Gly
              20                  25                  30

 gat ggc aca cag tca ctg gca gag ctc aaa gtt aag gga caa aaa agg      144
 Asp Gly Thr Gln Ser Leu Ala Glu Leu Lys Val Lys Gly Gln Lys Arg
          35                  40                  45

 aca agg ttt cca aga gag act gag tgt cgt gtc agt aaa gag ctg gta      192
 Thr Arg Phe Pro Arg Glu Thr Glu Cys Arg Val Ser Lys Glu Leu Val
      50                  55                  60

 aaa tta ggg ctg gac cag gtg gtg ggg gcg ctg agg agc tcg gca aca      240
 Lys Leu Gly Leu Asp Gln Val Val Gly Ala Leu Arg Ser Ser Ala Thr
  65                  70                  75                  80

 agg tta cca gca gaa tcc tcg gaa aac aag aag ccg atg gca aag cca      288
 Arg Leu Pro Ala Glu Ser Ser Glu Asn Lys Lys Pro Met Ala Lys Pro
                  85                  90                  95

 gat gat tta tta aaa ttt aca gct ctg gac cta aat tta tca cgt agc      336
 Asp Asp Leu Leu Lys Phe Thr Ala Leu Asp Leu Asn Leu Ser Arg Ser
             100                 105                 110

 acc aag aca cgc acc cca cca tgt ctg atc aat gac ctg gaa tac aga      384
 Thr Lys Thr Arg Thr Pro Pro Cys Leu Ile Asn Asp Leu Glu Tyr Arg
         115                 120                 125

 atc gat gga agt gcc tta agc ctg aga cag cag cag agg ccc ttc aaa      432
 Ile Asp Gly Ser Ala Leu Ser Leu Arg Gln Gln Gln Arg Pro Phe Lys
     130                 135                 140

 acc cga ctc cag gct ctg aaa tgc taa                                  459
 Thr Arg Leu Gln Ala Leu Lys Cys 
 145                 150





      <210> 399
      <211> 888
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(888)

      <400> 399
  atg agg att cgg cga tgg agc ctt atg ttt gac agt gtt tgg ccc atg      48
  Met Arg Ile Arg Arg Trp Ser Leu Met Phe Asp Ser Val Trp Pro Met
    1               5                  10                  15

 tgt gcc ttc tac agc tgg gct aaa gct tct aga aca ttc ctg aaa gca       96
 Cys Ala Phe Tyr Ser Trp Ala Lys Ala Ser Arg Thr Phe Leu Lys Ala
              20                  25                  30

 gat ggg ctc cct aga agg aag cag tgg gtt ctt gta gag gcc ttg gca      144
 Asp Gly Leu Pro Arg Arg Lys Gln Trp Val Leu Val Glu Ala Leu Ala
          35                  40                  45

 ggt gga gga gtt ctt ggg gtc aaa caa att aca att cag gtt ctg ttt      192
 Gly Gly Gly Val Leu Gly Val Lys Gln Ile Thr Ile Gln Val Leu Phe
      50                  55                  60

 gag gtg ctc ctg aga aga gga aaa gag tca gaa acc tac aca aag atg      240
 Glu Val Leu Leu Arg Arg Gly Lys Glu Ser Glu Thr Tyr Thr Lys Met
  65                  70                  75                  80

 tat aga aga tta ggt cct gag aga tgc cgg aga tca aag tat gct ggg      288
 Tyr Arg Arg Leu Gly Pro Glu Arg Cys Arg Arg Ser Lys Tyr Ala Gly
                  85                  90                  95

 gtt gaa agg att gta gac aag agg aag aac aag aaa gga aaa tgg gag      336
 Val Glu Arg Ile Val Asp Lys Arg Lys Asn Lys Lys Gly Lys Trp Glu
             100                 105                 110

 tat ctt atc cga tgg aaa ggc tac ggg agc acc gag gac acg tgg gag      384
 Tyr Leu Ile Arg Trp Lys Gly Tyr Gly Ser Thr Glu Asp Thr Trp Glu
         115                 120                 125

 ccg gag cac cac ctc ttg cac tgt gag gag ttt att gat gaa ttc aat      432
 Pro Glu His His Leu Leu His Cys Glu Glu Phe Ile Asp Glu Phe Asn
     130                 135                 140

 ggg ttg cac atg tcc aag gac aag agg atc aag tca ggg aag cag tcc      480
 Gly Leu His Met Ser Lys Asp Lys Arg Ile Lys Ser Gly Lys Gln Ser
 145                 150                 155                 160

 agt acc tcc aag ctg ctg cgt gac agt cga ggc ccg tcg gtt gag aaa      528
 Ser Thr Ser Lys Leu Leu Arg Asp Ser Arg Gly Pro Ser Val Glu Lys
                 165                 170                 175

 ctg tcc cac aga cct tca gat cct gga aag agc aag ggg acc tcc cat      576
 Leu Ser His Arg Pro Ser Asp Pro Gly Lys Ser Lys Gly Thr Ser His
             180                 185                 190

 aaa cgg aag cga att aac cct ccc ctg gcc aag cca aaa aaa ggg tat      624
 Lys Arg Lys Arg Ile Asn Pro Pro Leu Ala Lys Pro Lys Lys Gly Tyr
         195                 200                 205

 tca ggc aag ccc tct tca gga ggt gac agg gcc acc aag acg gtg tct      672
 Ser Gly Lys Pro Ser Ser Gly Gly Asp Arg Ala Thr Lys Thr Val Ser
     210                 215                 220

 tac agg act acc ccc agt ggt ttg caa ata atg ccc ctg aaa aag tct      720
 Tyr Arg Thr Thr Pro Ser Gly Leu Gln Ile Met Pro Leu Lys Lys Ser
 225                 230                 235                 240

 cag aac ggg atg gaa aat ggg gac gcc ggc tct gag aag gat gag agg      768
 Gln Asn Gly Met Glu Asn Gly Asp Ala Gly Ser Glu Lys Asp Glu Arg
                 245                 250                 255

 cac ttt gga aat ggg tcc cat cag cct ggc ttg gat ttg aat gat cat      816
 His Phe Gly Asn Gly Ser His Gln Pro Gly Leu Asp Leu Asn Asp His
             260                 265                 270

 gtt gga gag caa gat atg ggt gaa tgt gac gtg aat cac gct aca ctg      864
 Val Gly Glu Gln Asp Met Gly Glu Cys Asp Val Asn His Ala Thr Leu
         275                 280                 285

 gcg gag aac ggg ctc ggt ttg tag                                      888
 Ala Glu Asn Gly Leu Gly Leu 
     290                 295





      <210> 400
      <211> 777
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(777)

      <400> 400
  atg ccc tct ttg aag gca aat ttt gat ttg ctt gcc tgt ctg cgg ggc      48
  Met Pro Ser Leu Lys Ala Asn Phe Asp Leu Leu Ala Cys Leu Arg Gly
    1               5                  10                  15

 gtt ggc agc agc aca ctg ctc ctc tgg cca gca gtc ctg ggt gca cag       96
 Val Gly Ser Ser Thr Leu Leu Leu Trp Pro Ala Val Leu Gly Ala Gln
              20                  25                  30

 acc agg caa gct ggt gtc aac gaa ggg cgg tca cag gta gct gac ttc      144
 Thr Arg Gln Ala Gly Val Asn Glu Gly Arg Ser Gln Val Ala Asp Phe
          35                  40                  45

 ctt cgg atc ccc gtc act ggg tgc cca gaa cag cgc agg aac ccg ccg      192
 Leu Arg Ile Pro Val Thr Gly Cys Pro Glu Gln Arg Arg Asn Pro Pro
      50                  55                  60

 agt cct ccg gcc cct ctg ggc acc ggg ggt cct gcc gag gag cgc ctg      240
 Ser Pro Pro Ala Pro Leu Gly Thr Gly Gly Pro Ala Glu Glu Arg Leu
  65                  70                  75                  80

 cag ttt cct ggg gta gct ggg tcc agg cgg ggt cga ggc cgc atc ttg      288
 Gln Phe Pro Gly Val Ala Gly Ser Arg Arg Gly Arg Gly Arg Ile Leu
                  85                  90                  95

 cga gcg ggt ggc att ggc agg gca tct ccg ggc gag ggc acc ggc gcc      336
 Arg Ala Gly Gly Ile Gly Arg Ala Ser Pro Gly Glu Gly Thr Gly Ala
             100                 105                 110

 cca cgg ccg cgc gca ggg cag ggg cgc ggg ggc ccc ggg aag ccc gag      384
 Pro Arg Pro Arg Ala Gly Gln Gly Arg Gly Gly Pro Gly Lys Pro Glu
         115                 120                 125

 agc gga gga ggc ggc ccc gtg gcc ctg cgg cca ggc gac tgt acc tgc      432
 Ser Gly Gly Gly Gly Pro Val Ala Leu Arg Pro Gly Asp Cys Thr Cys
     130                 135                 140

 tgc gtg ctg aag tcc cag ccc agg cag cag cgg cga ggg gcg tgc tcc      480
 Cys Val Leu Lys Ser Gln Pro Arg Gln Gln Arg Arg Gly Ala Cys Ser
 145                 150                 155                 160

 gcc atg gcc ttt cgg gta agg ctg cgc gtc cgt cag tcc gtc cgt ccg      528
 Ala Met Ala Phe Arg Val Arg Leu Arg Val Arg Gln Ser Val Arg Pro
                 165                 170                 175

 cca cgc ggc gtg ata gtc gcc gcg ctc cag cgc cca gag acg cag ggg      576
 Pro Arg Gly Val Ile Val Ala Ala Leu Gln Arg Pro Glu Thr Gln Gly
             180                 185                 190

 ccc gcc cct agc tcc gcc cgg ccg gac tgt gga ccg gag tca cga ggc      624
 Pro Ala Pro Ser Ser Ala Arg Pro Asp Cys Gly Pro Glu Ser Arg Gly
         195                 200                 205

 ggg ctt gcg ctc tgg cgc cgc ctg cgg ggc tac gcg agc cgg gac cgc      672
 Gly Leu Ala Leu Trp Arg Arg Leu Arg Gly Tyr Ala Ser Arg Asp Arg
     210                 215                 220

 gtc ctg tgc aat cga cgg tgc ccc cac gca gcc cgc ttt cct tcg aag      720
 Val Leu Cys Asn Arg Arg Cys Pro His Ala Ala Arg Phe Pro Ser Lys
 225                 230                 235                 240

 cgc acc ccc tct ggt tct ccc cat ctt cat ctt atg tct tca tgg gcc      768
 Arg Thr Pro Ser Gly Ser Pro His Leu His Leu Met Ser Ser Trp Ala
                 245                 250                 255

 gtg ccc tga                                                          777
 Val Pro 






      <210> 401
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 401
  atg agg gag tgg gag gtg gct gtg ccg cag acc ctg tct cct gcc ctg      48
  Met Arg Glu Trp Glu Val Ala Val Pro Gln Thr Leu Ser Pro Ala Leu
    1               5                  10                  15

 tct ctg gct gcc agg gca gcc agc ctc ttt ctt cta gct ctc tgg gat       96
 Ser Leu Ala Ala Arg Ala Ala Ser Leu Phe Leu Leu Ala Leu Trp Asp
              20                  25                  30

 ggc aaa gtc ctt gct tgc ttc ttt gca ccc act aaa tat gag ctt gct      144
 Gly Lys Val Leu Ala Cys Phe Phe Ala Pro Thr Lys Tyr Glu Leu Ala
          35                  40                  45

 act cag tca tgg cca aag aaa ggc tat caa act ctg gaa agt gct ctt      192
 Thr Gln Ser Trp Pro Lys Lys Gly Tyr Gln Thr Leu Glu Ser Ala Leu
      50                  55                  60

 gat tgt tgc agg aag ctg ctg gct ggg ctg cat tta gct gga ctg ctg      240
 Asp Cys Cys Arg Lys Leu Leu Ala Gly Leu His Leu Ala Gly Leu Leu
  65                  70                  75                  80

 tct gtc cag gct gtc aac cag tca ctc ctg gag tcc tgg gga gca cct      288
 Ser Val Gln Ala Val Asn Gln Ser Leu Leu Glu Ser Trp Gly Ala Pro
                  85                  90                  95

 cat cca gca gag cct gtc gta tgt gca ggg gcg gca tgg ccc agg cta      336
 His Pro Ala Glu Pro Val Val Cys Ala Gly Ala Ala Trp Pro Arg Leu
             100                 105                 110

 atg ggg ttg aag tac cct gtg tca ttt ggg aag tct gca gaa ttc cat      384
 Met Gly Leu Lys Tyr Pro Val Ser Phe Gly Lys Ser Ala Glu Phe His
         115                 120                 125

 gaa ggt gat gtt caa atg cct ctg gaa aaa ctg tgg gaa ggt gct gag      432
 Glu Gly Asp Val Gln Met Pro Leu Glu Lys Leu Trp Glu Gly Ala Glu
     130                 135                 140

 cac tgc agc agg tat cca gaa aca cat ccg aac cat cca tct ggg gcc      480
 His Cys Ser Arg Tyr Pro Glu Thr His Pro Asn His Pro Ser Gly Ala
 145                 150                 155                 160

 aca gtc aat gtg gtg gct ctg ttc cct gga gtt ctg agg att caa gct      528
 Thr Val Asn Val Val Ala Leu Phe Pro Gly Val Leu Arg Ile Gln Ala
                 165                 170                 175

 ccc cat cca act cac tac cat cct act cat cca act cat cca cca ttc      576
 Pro His Pro Thr His Tyr His Pro Thr His Pro Thr His Pro Pro Phe
             180                 185                 190

 cta cgg cct ctt cct caa gct gaa gat gga gac atc cat gtt cca gat      624
 Leu Arg Pro Leu Pro Gln Ala Glu Asp Gly Asp Ile His Val Pro Asp
         195                 200                 205

 agc aca acg gag aaa ggt cac tta gca cca tcc ctg gca agc aat atg      672
 Ser Thr Thr Glu Lys Gly His Leu Ala Pro Ser Leu Ala Ser Asn Met
     210                 215                 220

 tgc tct cca agt gat gac gcc aac gct tat gat gac aat gat gat gaa      720
 Cys Ser Pro Ser Asp Asp Ala Asn Ala Tyr Asp Asp Asn Asp Asp Glu
 225                 230                 235                 240

 aat gat gac cat gat gac aat tag                                      744
 Asn Asp Asp His Asp Asp Asn 
                 245





      <210> 402
      <211> 1071
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1071)

      <400> 402
  atg gag gaa tcc agg gga cct ctg ggt gct ggt gac acc ggt gtg ttc      48
  Met Glu Glu Ser Arg Gly Pro Leu Gly Ala Gly Asp Thr Gly Val Phe
    1               5                  10                  15

 aca ttg cga gtt aag cta gtg gta cac gta tgg ttt gtg aac gct ctg       96
 Thr Leu Arg Val Lys Leu Val Val His Val Trp Phe Val Asn Ala Leu
              20                  25                  30

 ttc ata agt tta ctc gat agt gac tta aag gac agc aac acg cac tct      144
 Phe Ile Ser Leu Leu Asp Ser Asp Leu Lys Asp Ser Asn Thr His Ser
          35                  40                  45

 gtc tca cca agc gcc tgg cat ata ctt ggc act cga ctc ttc cct gag      192
 Val Ser Pro Ser Ala Trp His Ile Leu Gly Thr Arg Leu Phe Pro Glu
      50                  55                  60

 cac aca gca ctt gag aac gta gct gcc cct ggt ggc tgc aga gct ctc      240
 His Thr Ala Leu Glu Asn Val Ala Ala Pro Gly Gly Cys Arg Ala Leu
  65                  70                  75                  80

 tgc tgg aca cag aat gct tcc tgt cct ctg ctt cct gga aca ctc acc      288
 Cys Trp Thr Gln Asn Ala Ser Cys Pro Leu Leu Pro Gly Thr Leu Thr
                  85                  90                  95

 cca gag cct ccc tcc cac tcc ttc cca gcc cct ggg gcc aag tct ggt      336
 Pro Glu Pro Pro Ser His Ser Phe Pro Ala Pro Gly Ala Lys Ser Gly
             100                 105                 110

 gcc tgt gtt tgg gtg gga gaa ggg ggc acc gtg aac tct gag gtc acc      384
 Ala Cys Val Trp Val Gly Glu Gly Gly Thr Val Asn Ser Glu Val Thr
         115                 120                 125

 tgg atg cta gaa ttc act gac tcc aac att cta agc tgc tgc tca act      432
 Trp Met Leu Glu Phe Thr Asp Ser Asn Ile Leu Ser Cys Cys Ser Thr
     130                 135                 140

 tct gca ggg atc tgc tct gat ttc tgc gga atg tgc cct tat cca ggg      480
 Ser Ala Gly Ile Cys Ser Asp Phe Cys Gly Met Cys Pro Tyr Pro Gly
 145                 150                 155                 160

 atc atc tcc tca tcg cag ggg gca gga tgg cag gag aat gtt cag acc      528
 Ile Ile Ser Ser Ser Gln Gly Ala Gly Trp Gln Glu Asn Val Gln Thr
                 165                 170                 175

 agt tac ctg cct tcc cca aat ggt aat agg aag ggt ctt ccc aga tcc      576
 Ser Tyr Leu Pro Ser Pro Asn Gly Asn Arg Lys Gly Leu Pro Arg Ser
             180                 185                 190

 tcc tta tca ccc atc ata gcc aag tgg tgg gca tgt gac ctg aaa aca      624
 Ser Leu Ser Pro Ile Ile Ala Lys Trp Trp Ala Cys Asp Leu Lys Thr
         195                 200                 205

 cag ctg gag ccc cct ggg gct gga gca agg cag cct ccc ctt ccc cct      672
 Gln Leu Glu Pro Pro Gly Ala Gly Ala Arg Gln Pro Pro Leu Pro Pro
     210                 215                 220

 gac tca ccg agg tac tgt atg att tca gac ctt ttt att gac aac tat      720
 Asp Ser Pro Arg Tyr Cys Met Ile Ser Asp Leu Phe Ile Asp Asn Tyr
 225                 230                 235                 240

 cag gtt aaa tgt att aat ggg aag atg tgt tat gtg cag aag cag ccg      768
 Gln Val Lys Cys Ile Asn Gly Lys Met Cys Tyr Val Gln Lys Gln Pro
                 245                 250                 255

 gca cca cat tcc cac aga atg agc cct gag gag gtc tct gca cac gat      816
 Ala Pro His Ser His Arg Met Ser Pro Glu Glu Val Ser Ala His Asp
             260                 265                 270

 gcc tta att tca aaa gag agc aat aca cca aaa ata gat cac tgc tct      864
 Ala Leu Ile Ser Lys Glu Ser Asn Thr Pro Lys Ile Asp His Cys Ser
         275                 280                 285

 tct ccc tca agt tct gag gac tct ggg atc aat gcg att ggg gct cac      912
 Ser Pro Ser Ser Ser Glu Asp Ser Gly Ile Asn Ala Ile Gly Ala His
     290                 295                 300

 tat gtg gaa tcg tgt gac gag gac aca gaa gaa gga gca gaa ctg agt      960
 Tyr Val Glu Ser Cys Asp Glu Asp Thr Glu Glu Gly Ala Glu Leu Ser
 305                 310                 315                 320

 tca gag gaa gat tac agt cca gag agc agc tgg gaa ccg gat gag tgc     1008
 Ser Glu Glu Asp Tyr Ser Pro Glu Ser Ser Trp Glu Pro Asp Glu Cys
                 325                 330                 335

 acc ctt ctc tcc ccc tcg cag tct gac ctg gaa gtg att gaa acg ata     1056
 Thr Leu Leu Ser Pro Ser Gln Ser Asp Leu Glu Val Ile Glu Thr Ile
             340                 345                 350

 gaa acg act gtg tga                                                 1071
 Glu Thr Thr Val 
         355





      <210> 403
      <211> 621
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(621)

      <400> 403
  atg gcc atc cca gtg ctg atg gca gtg gaa gag ctc atc caa ctg gta      48
  Met Ala Ile Pro Val Leu Met Ala Val Glu Glu Leu Ile Gln Leu Val
    1               5                  10                  15

 cag ttg tta ttt ctg gca gtg aat cac atc cac acc atg gca cac ctt       96
 Gln Leu Leu Phe Leu Ala Val Asn His Ile His Thr Met Ala His Leu
              20                  25                  30

 gct cag aga gtt tcc atc tcc att aac aga aaa agc aac cta tat ccc      144
 Ala Gln Arg Val Ser Ile Ser Ile Asn Arg Lys Ser Asn Leu Tyr Pro
          35                  40                  45

 tcc cct gac cca ggt ttc cag ggt ctg ctg cag ccc atg cag atc caa      192
 Ser Pro Asp Pro Gly Phe Gln Gly Leu Leu Gln Pro Met Gln Ile Gln
      50                  55                  60

 aag tgg tct gca cag gcc tgt ggc agg gcc act gtg att tta gga cat      240
 Lys Trp Ser Ala Gln Ala Cys Gly Arg Ala Thr Val Ile Leu Gly His
  65                  70                  75                  80

 atg acc tat gtg ggt cat aaa aag gaa atc tta ggc aaa cac tca cag      288
 Met Thr Tyr Val Gly His Lys Lys Glu Ile Leu Gly Lys His Ser Gln
                  85                  90                  95

 gaa gct ctg ctg gac aat gtc caa gaa gcc aga gcc cag ctg gac acg      336
 Glu Ala Leu Leu Asp Asn Val Gln Glu Ala Arg Ala Gln Leu Asp Thr
             100                 105                 110

 ctg gtc tct cca ggg cta ccg ctt ttc ctc tcc ctg aac ctc aga gca      384
 Leu Val Ser Pro Gly Leu Pro Leu Phe Leu Ser Leu Asn Leu Arg Ala
         115                 120                 125

 gag ctg cct ggg atg ttc att aaa gac ctg cag tac ccc agg tac tgg      432
 Glu Leu Pro Gly Met Phe Ile Lys Asp Leu Gln Tyr Pro Arg Tyr Trp
     130                 135                 140

 ggg aac agt ggg aac agg acc ttc ctg gcc cca gct gca tcc att gac      480
 Gly Asn Ser Gly Asn Arg Thr Phe Leu Ala Pro Ala Ala Ser Ile Asp
 145                 150                 155                 160

 att gca ccg gag gcc atg gaa gtc ctt cag ctg ggt act ctc aac cac      528
 Ile Ala Pro Glu Ala Met Glu Val Leu Gln Leu Gly Thr Leu Asn His
                 165                 170                 175

 aga cag ctc cag tcc aag ctg aag tcc agg acc acg ctg gaa ggc tgc      576
 Arg Gln Leu Gln Ser Lys Leu Lys Ser Arg Thr Thr Leu Glu Gly Cys
             180                 185                 190

 aca ccc ttg gaa ggc acc caa gga aga gag gca ggc atc tgc tga          621
 Thr Pro Leu Glu Gly Thr Gln Gly Arg Glu Ala Gly Ile Cys 
         195                 200                 205





      <210> 404
      <211> 555
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(555)

      <400> 404
  atg gcg agt gaa acg ctt cct gga gga agc atc atg ctt ctg ggg gtc      48
  Met Ala Ser Glu Thr Leu Pro Gly Gly Ser Ile Met Leu Leu Gly Val
    1               5                  10                  15

 atg ctg aag cct ttt gtc ttc ctg gag tca gtg gtg agg ctg gtg atg       96
 Met Leu Lys Pro Phe Val Phe Leu Glu Ser Val Val Arg Leu Val Met
              20                  25                  30

 gat gag ggt tat ctg atg ggg aat gga cct ccc ata agg gaa gta gta      144
 Asp Glu Gly Tyr Leu Met Gly Asn Gly Pro Pro Ile Arg Glu Val Val
          35                  40                  45

 tca gaa aag tat tct tgt gag gaa aac aca gag gag aac aaa gag agc      192
 Ser Glu Lys Tyr Ser Cys Glu Glu Asn Thr Glu Glu Asn Lys Glu Ser
      50                  55                  60

 agg ttg atg gtt cta acc ttg gag agt gtg gag gaa aac agg gca ctg      240
 Arg Leu Met Val Leu Thr Leu Glu Ser Val Glu Glu Asn Arg Ala Leu
  65                  70                  75                  80

 aca gca gca gag ggc atg aca tac tcc ttt gca gga ttt ctt cgt ttc      288
 Thr Ala Ala Glu Gly Met Thr Tyr Ser Phe Ala Gly Phe Leu Arg Phe
                  85                  90                  95

 caa gca aat acc ctg tac atc ctg gac tgg tgg agc cag cga gag gct      336
 Gln Ala Asn Thr Leu Tyr Ile Leu Asp Trp Trp Ser Gln Arg Glu Ala
             100                 105                 110

 gga gct gga gcc tat cgg ctg ggc ccc gcc tcg cct cag ggg aca ctg      384
 Gly Ala Gly Ala Tyr Arg Leu Gly Pro Ala Ser Pro Gln Gly Thr Leu
         115                 120                 125

 ctc gga gac aaa gcc cgg ggc cct ggc caa ggg cac cgc gga ggc gcc      432
 Leu Gly Asp Lys Ala Arg Gly Pro Gly Gln Gly His Arg Gly Gly Ala
     130                 135                 140

 ttc cca gac gcg gat gac gtg gct gtc ctg act gac ggg aag gaa aat      480
 Phe Pro Asp Ala Asp Asp Val Ala Val Leu Thr Asp Gly Lys Glu Asn
 145                 150                 155                 160

 ggc tgc tcg ccc agc tcc atc acc agc agc ggc ttg tgg aca act cgc      528
 Gly Cys Ser Pro Ser Ser Ile Thr Ser Ser Gly Leu Trp Thr Thr Arg
                 165                 170                 175

 cca cgc atc cct ggt ggc ggt ccc tga                                  555
 Pro Arg Ile Pro Gly Gly Gly Pro 
             180





      <210> 405
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 405
  atg aga cca tat gct gct ctg gga gtc aca tgg atc ctc gga gca ggc      48
  Met Arg Pro Tyr Ala Ala Leu Gly Val Thr Trp Ile Leu Gly Ala Gly
    1               5                  10                  15

 cta ctg gtt gag atc tac aca gac tgg gcc aat cat tac cta gcc aaa       96
 Leu Leu Val Glu Ile Tyr Thr Asp Trp Ala Asn His Tyr Leu Ala Lys
              20                  25                  30

 tcc ggc cac aag cgt ctc atc agg gat ctc cag caa gat gtg aca gat      144
 Ser Gly His Lys Arg Leu Ile Arg Asp Leu Gln Gln Asp Val Thr Asp
          35                  40                  45

 ggc gtc ctc ctg gcc cag att atc cag gtt gtg gct cct tgc cac atg      192
 Gly Val Leu Leu Ala Gln Ile Ile Gln Val Val Ala Pro Cys His Met
      50                  55                  60

 ggc ctc cca ata tct gcc tgc ttc ctc aat gcc agc atg gga gaa agc      240
 Gly Leu Pro Ile Ser Ala Cys Phe Leu Asn Ala Ser Met Gly Glu Ser
  65                  70                  75                  80

 ttc tgg aac aag tct gct aac aag atg acg acc ttg ccc cag ctg tcc      288
 Phe Trp Asn Lys Ser Ala Asn Lys Met Thr Thr Leu Pro Gln Leu Ser
                  85                  90                  95

 ctg gag gac ggc agc tcg atg aca aat gaa aag att gaa gac atc aat      336
 Leu Glu Asp Gly Ser Ser Met Thr Asn Glu Lys Ile Glu Asp Ile Asn
             100                 105                 110

 ggc tgt ccg aag aac aga tcc caa atg aac aca aga ata taa              378
 Gly Cys Pro Lys Asn Arg Ser Gln Met Asn Thr Arg Ile 
         115                 120                 125





      <210> 406
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 406
  atg ggg att tcg ctg acg ttc ttc aga agc tct gcg ctg cgg gcc tcc      48
  Met Gly Ile Ser Leu Thr Phe Phe Arg Ser Ser Ala Leu Arg Ala Ser
    1               5                  10                  15

 gtg tcc ctt cta ctc ccg ctg tct gaa ccc cgc gat gtc ccc cgc gct       96
 Val Ser Leu Leu Leu Pro Leu Ser Glu Pro Arg Asp Val Pro Arg Ala
              20                  25                  30

 gtt cgt ccc ctc ttc gtc tcc ctc ttc gat gtt ccg ggt ccc aga aac      144
 Val Arg Pro Leu Phe Val Ser Leu Phe Asp Val Pro Gly Pro Arg Asn
          35                  40                  45

 cag gtt atc aca gtg gcc cgg atc ata ggg aaa ttg cga aat cat cca      192
 Gln Val Ile Thr Val Ala Arg Ile Ile Gly Lys Leu Arg Asn His Pro
      50                  55                  60

 gtt ggg atc acc gag cct gca ggg tcc cct tcc tgg gcg agc ctc ctg      240
 Val Gly Ile Thr Glu Pro Ala Gly Ser Pro Ser Trp Ala Ser Leu Leu
  65                  70                  75                  80

 gcc ccg tgc tat cgg agg cct gga cac ccc cgc cag gga ccc agc gac      288
 Ala Pro Cys Tyr Arg Arg Pro Gly His Pro Arg Gln Gly Pro Ser Asp
                  85                  90                  95

 cca gca agt ccc cac ccc ctc taa                                      312
 Pro Ala Ser Pro His Pro Leu 
             100





      <210> 407
      <211> 303
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(303)

      <400> 407
  atg acc tgt tcc aac cac aga tta tct aag cga gct ccc tcc ctg cgt      48
  Met Thr Cys Ser Asn His Arg Leu Ser Lys Arg Ala Pro Ser Leu Arg
    1               5                  10                  15

 ctt gct ctt tgg gta ttt gca ttt cag cca aat ttg ctc cga att gct       96
 Leu Ala Leu Trp Val Phe Ala Phe Gln Pro Asn Leu Leu Arg Ile Ala
              20                  25                  30

 aga ggg ggt acc gtt gtc ttc ctc act caa tgg gct gtc cct gct cct      144
 Arg Gly Gly Thr Val Val Phe Leu Thr Gln Trp Ala Val Pro Ala Pro
          35                  40                  45

 ttg tct tgc aca gga aat tcc aga ctc aga gtc cag tgg agg agg aaa      192
 Leu Ser Cys Thr Gly Asn Ser Arg Leu Arg Val Gln Trp Arg Arg Lys
      50                  55                  60

 gca ggg act ctg ctg gat tct ctt tcg aac act ggg att gag ggt gtt      240
 Ala Gly Thr Leu Leu Asp Ser Leu Ser Asn Thr Gly Ile Glu Gly Val
  65                  70                  75                  80

 tgc ctc gtg gaa ctg aac aat gtg ggt gaa aag cag gtg gaa aac ttg      288
 Cys Leu Val Glu Leu Asn Asn Val Gly Glu Lys Gln Val Glu Asn Leu
                  85                  90                  95

 cag ggg gca gca tag                                                  303
 Gln Gly Ala Ala 
             100





      <210> 408
      <211> 459
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(459)

      <400> 408
  atg cca gca tcc ctg gtg gtc ttc ctg tgc cac tgc agc atg cag gta      48
  Met Pro Ala Ser Leu Val Val Phe Leu Cys His Cys Ser Met Gln Val
    1               5                  10                  15

 gcc ttt ggt gca gca gac tgt atg cgc cag ggg aac gac cat ggc act       96
 Ala Phe Gly Ala Ala Asp Cys Met Arg Gln Gly Asn Asp His Gly Thr
              20                  25                  30

 cag tac cgc tcg gcc atc tac ccg acc tct gcc aag caa atg gag gca      144
 Gln Tyr Arg Ser Ala Ile Tyr Pro Thr Ser Ala Lys Gln Met Glu Ala
          35                  40                  45

 gcc ctg agc tcc aaa aag aac tac caa aag agc ggg acg gcc atg gaa      192
 Ala Leu Ser Ser Lys Lys Asn Tyr Gln Lys Ser Gly Thr Ala Met Glu
      50                  55                  60

 cat ggg acg gcc acg gaa cat ggg ttc ctg ccc atc aga gtg ctg cac      240
 His Gly Thr Ala Thr Glu His Gly Phe Leu Pro Ile Arg Val Leu His
  65                  70                  75                  80

 cgg gag ctg ctc tca cct ttt cct gcc tgg aga cca cag cat gag ggt      288
 Arg Glu Leu Leu Ser Pro Phe Pro Ala Trp Arg Pro Gln His Glu Gly
                  85                  90                  95

 caa gtt ttt tct ttt tca gga acc aaa gtg tct ctt tgt gta ccc cat      336
 Gln Val Phe Ser Phe Ser Gly Thr Lys Val Ser Leu Cys Val Pro His
             100                 105                 110

 cct gat gag tca gct tgg gga tat tca tct gag cag ata agt gcc aat      384
 Pro Asp Glu Ser Ala Trp Gly Tyr Ser Ser Glu Gln Ile Ser Ala Asn
         115                 120                 125

 gtt gcc atg gag aga aaa ggc gcc agc gtt ttg ttc tgg gac gtg ctg      432
 Val Ala Met Glu Arg Lys Gly Ala Ser Val Leu Phe Trp Asp Val Leu
     130                 135                 140

 tca cac acg ctc gtg ggc agg tca tga                                  459
 Ser His Thr Leu Val Gly Arg Ser 
 145                 150





      <210> 409
      <211> 750
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(750)

      <400> 409
  atg gca gcc atg ttg gag aac ctc ctg ttt gta ttt ctc cta gtt ggg      48
  Met Ala Ala Met Leu Glu Asn Leu Leu Phe Val Phe Leu Leu Val Gly
    1               5                  10                  15

 gca gga ctc ttc tgc acc atg gag cca gag cca gtc cag ccc ggc atg       96
 Ala Gly Leu Phe Cys Thr Met Glu Pro Glu Pro Val Gln Pro Gly Met
              20                  25                  30

 ctt atc gat gtc tgc aag tac ctg ggc tcc ctg cag tac cgc gtc tgg      144
 Leu Ile Asp Val Cys Lys Tyr Leu Gly Ser Leu Gln Tyr Arg Val Trp
          35                  40                  45

 aag aag atg ctt gca tct gtg gaa tct gta ccc ttc agc ttt gac ccc      192
 Lys Lys Met Leu Ala Ser Val Glu Ser Val Pro Phe Ser Phe Asp Pro
      50                  55                  60

 aac acc gca gct ggc tgg ctc tcc gtg tct gac gac ctc acc agc gtc      240
 Asn Thr Ala Ala Gly Trp Leu Ser Val Ser Asp Asp Leu Thr Ser Val
  65                  70                  75                  80

 acc aac cat ggc tac cgc gtg cag gtg gag aac ccg gaa cgc ttc tcc      288
 Thr Asn His Gly Tyr Arg Val Gln Val Glu Asn Pro Glu Arg Phe Ser
                  85                  90                  95

 tcg gcg ccc tgc ctg ctg ggc tcc cgt gtc ttc tca cag ggc tcg cac      336
 Ser Ala Pro Cys Leu Leu Gly Ser Arg Val Phe Ser Gln Gly Ser His
             100                 105                 110

 gcc tgg gag gtg gcc ctt ggg ggg ctg cag agc tgg agg gtg ggc gtg      384
 Ala Trp Glu Val Ala Leu Gly Gly Leu Gln Ser Trp Arg Val Gly Val
         115                 120                 125

 gta cgt gtg cgc cag gac tcg ggc gct gag ggc cac tca cac agc tgc      432
 Val Arg Val Arg Gln Asp Ser Gly Ala Glu Gly His Ser His Ser Cys
     130                 135                 140

 tac cac gac aca cgc tcg ggc ttc tgg tat gtc tgc cgc acg cag ggc      480
 Tyr His Asp Thr Arg Ser Gly Phe Trp Tyr Val Cys Arg Thr Gln Gly
 145                 150                 155                 160

 gtg gag ggg gac cac tgc gtg acc tcg gac cca gcc acg tcg ccc ctg      528
 Val Glu Gly Asp His Cys Val Thr Ser Asp Pro Ala Thr Ser Pro Leu
                 165                 170                 175

 gtc ctg gcc atc cca cgc cgc ctg cgt gtg gag ctg gag tgt gag gag      576
 Val Leu Ala Ile Pro Arg Arg Leu Arg Val Glu Leu Glu Cys Glu Glu
             180                 185                 190

 ggc gag ctg tct ttc tat gac gcg gag cgc cac tgc cac ctg tac acc      624
 Gly Glu Leu Ser Phe Tyr Asp Ala Glu Arg His Cys His Leu Tyr Thr
         195                 200                 205

 ttc cac gcc cgc ttt ggg gag gtt cgc ccc tac ttc tac ctg ggg ggt      672
 Phe His Ala Arg Phe Gly Glu Val Arg Pro Tyr Phe Tyr Leu Gly Gly
     210                 215                 220

 gca cgg ggc gcc ggg cct cca gag cct ttg cgc atc tgc ccc ttg cac      720
 Ala Arg Gly Ala Gly Pro Pro Glu Pro Leu Arg Ile Cys Pro Leu His
 225                 230                 235                 240

 atc agt gtc aag gaa gaa ctg gat ggc tga                              750
 Ile Ser Val Lys Glu Glu Leu Asp Gly 
                 245





      <210> 410
      <211> 507
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(507)

      <400> 410
  atg ttc cca cta att tcc agc cat cac ctt tgg tgg ggt ggg ctt cgg      48
  Met Phe Pro Leu Ile Ser Ser His His Leu Trp Trp Gly Gly Leu Arg
    1               5                  10                  15

 agg aca gtc tgt ctg aac ctg cca gtg ctg acc ctg cag cac ttt cag       96
 Arg Thr Val Cys Leu Asn Leu Pro Val Leu Thr Leu Gln His Phe Gln
              20                  25                  30

 cat atg cac atc aaa gtt gga gac cgc gct gaa ctt agg agg gcc ttc      144
 His Met His Ile Lys Val Gly Asp Arg Ala Glu Leu Arg Arg Ala Phe
          35                  40                  45

 aca cag act gat gtg gct acc ttc tca gaa tta aca ggg gat gtc aat      192
 Thr Gln Thr Asp Val Ala Thr Phe Ser Glu Leu Thr Gly Asp Val Asn
      50                  55                  60

 cct ttg cat ttg aat gaa gac ttt gca aaa cac acc aag ttt gga aat      240
 Pro Leu His Leu Asn Glu Asp Phe Ala Lys His Thr Lys Phe Gly Asn
  65                  70                  75                  80

 aca att gta cat gga gtt ttg atc aac gga ctt atc tca gct ctc cta      288
 Thr Ile Val His Gly Val Leu Ile Asn Gly Leu Ile Ser Ala Leu Leu
                  85                  90                  95

 gga act aaa atg cca ggg cca ggc tgt gta ttt ctt tcc cag gaa att      336
 Gly Thr Lys Met Pro Gly Pro Gly Cys Val Phe Leu Ser Gln Glu Ile
             100                 105                 110

 agc ttt cca gcc cct tta tat att gga gaa gtt gtt tta gct tct gca      384
 Ser Phe Pro Ala Pro Leu Tyr Ile Gly Glu Val Val Leu Ala Ser Ala
         115                 120                 125

 gaa gtg aaa aag ctg aag cgg ttc att gct att att gca gtg tca tgt      432
 Glu Val Lys Lys Leu Lys Arg Phe Ile Ala Ile Ile Ala Val Ser Cys
     130                 135                 140

 tct gta ata gaa agt aaa aag act gtt atg gaa ggc tgg gtt aaa gtt      480
 Ser Val Ile Glu Ser Lys Lys Thr Val Met Glu Gly Trp Val Lys Val
 145                 150                 155                 160

 atg gtt cca gaa gct tcc aaa tcc tga                                  507
 Met Val Pro Glu Ala Ser Lys Ser 
                 165





      <210> 411
      <211> 252
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(252)

      <400> 411
  atg gtg act gaa gct gcc aca ggt ctt cta ttg acc aca cta caa gga      48
  Met Val Thr Glu Ala Ala Thr Gly Leu Leu Leu Thr Thr Leu Gln Gly
    1               5                  10                  15

 ctc ttc ttg gtc act gat gac agc tgt tgt ctg tct gcc att ggc cac       96
 Leu Phe Leu Val Thr Asp Asp Ser Cys Cys Leu Ser Ala Ile Gly His
              20                  25                  30

 act atc cag ttc tca ctg gcc aag cag cag ctg cct gca ctt ggt acc      144
 Thr Ile Gln Phe Ser Leu Ala Lys Gln Gln Leu Pro Ala Leu Gly Thr
          35                  40                  45

 aag gta gat gcc agg gca gta gga gta gga cac aca gag ctt ccc ttc      192
 Lys Val Asp Ala Arg Ala Val Gly Val Gly His Thr Glu Leu Pro Phe
      50                  55                  60

 atg tgt gtc cag tct ggt aaa ctg ggc aag tac aag aca cag aca cag      240
 Met Cys Val Gln Ser Gly Lys Leu Gly Lys Tyr Lys Thr Gln Thr Gln
  65                  70                  75                  80

 tta atg gaa tga                                                      252
 Leu Met Glu 






      <210> 412
      <211> 174
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(174)

      <400> 412
  atg aaa gac ttt gct gag ttc aag cag aga aag gcc aat tgt gtc atg      48
  Met Lys Asp Phe Ala Glu Phe Lys Gln Arg Lys Ala Asn Cys Val Met
    1               5                  10                  15

 aga tta gta acg gtg tgg atc ttg aac cca ctg ttc tgt cat gcc ctg       96
 Arg Leu Val Thr Val Trp Ile Leu Asn Pro Leu Phe Cys His Ala Leu
              20                  25                  30

 tgg aaa ttc tta ctc tat ttt ata gaa tgg gat gct gcc cca att cat      144
 Trp Lys Phe Leu Leu Tyr Phe Ile Glu Trp Asp Ala Ala Pro Ile His
          35                  40                  45

 gaa tcg caa ata aaa gcc aat tcg atc taa                              174
 Glu Ser Gln Ile Lys Ala Asn Ser Ile 
      50                  55





      <210> 413
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 413
  atg ctc cag gct ctg ctc caa gct ctg agc atc ctc aca atc acc gct      48
  Met Leu Gln Ala Leu Leu Gln Ala Leu Ser Ile Leu Thr Ile Thr Ala
    1               5                  10                  15

 gga ggt ctg tcc tat gac ggt cct gtg tta cag atg agg acc cag gag       96
 Gly Gly Leu Ser Tyr Asp Gly Pro Val Leu Gln Met Arg Thr Gln Glu
              20                  25                  30

 agg gag gtg acc aag ggc tgg tgg ctg gtg aaa ggc ctg ttg gag gca      144
 Arg Glu Val Thr Lys Gly Trp Trp Leu Val Lys Gly Leu Leu Glu Ala
          35                  40                  45

 gct gag gct gtg cca aag aga tgc tac tgg tcc ccc ata tcc att ctc      192
 Ala Glu Ala Val Pro Lys Arg Cys Tyr Trp Ser Pro Ile Ser Ile Leu
      50                  55                  60

 ttc tcc tcc atc aat aag ata act ccc aag gct tgg atg cac aca gga      240
 Phe Ser Ser Ile Asn Lys Ile Thr Pro Lys Ala Trp Met His Thr Gly
  65                  70                  75                  80

 ggg tgg gcg ctg gag cag ccg ctg tgt acc cag aat tgg aag gcc aca      288
 Gly Trp Ala Leu Glu Gln Pro Leu Cys Thr Gln Asn Trp Lys Ala Thr
                  85                  90                  95

 cct aca act gga ctc ttg gcc ttg caa gga ctg agt gca cag tcc aca      336
 Pro Thr Thr Gly Leu Leu Ala Leu Gln Gly Leu Ser Ala Gln Ser Thr
             100                 105                 110

 aga cag caa tgt gaa agg gag aag gaa cgt caa cgc cgg gtt tag          381
 Arg Gln Gln Cys Glu Arg Glu Lys Glu Arg Gln Arg Arg Val 
         115                 120                 125





      <210> 414
      <211> 258
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(258)

      <400> 414
  atg gtt ttc tgc cag act ctt gtg gcc act gtc tgt gcc ttc tct gag      48
  Met Val Phe Cys Gln Thr Leu Val Ala Thr Val Cys Ala Phe Ser Glu
    1               5                  10                  15

 cag ctc atg gcg gcc ttg aac cag atg ttt gac aac agc aag gaa aat       96
 Gln Leu Met Ala Ala Leu Asn Gln Met Phe Asp Asn Ser Lys Glu Asn
              20                  25                  30

 gag atg gaa act tgg gaa gcc agc agg agg tgg ctg gac cag ata gcg      144
 Glu Met Glu Thr Trp Glu Ala Ser Arg Arg Trp Leu Asp Gln Ile Ala
          35                  40                  45

 aat gca ggt gtt ctt ttt cac ttt cag tca ctt ctg tca cca aac ttg      192
 Asn Ala Gly Val Leu Phe His Phe Gln Ser Leu Leu Ser Pro Asn Leu
      50                  55                  60

 tcg aag gac aca ggc tgc tgt gaa acc aaa gct cct att gag atg gat      240
 Ser Lys Asp Thr Gly Cys Cys Glu Thr Lys Ala Pro Ile Glu Met Asp
  65                  70                  75                  80

 gtc ctg gag cag gct tga                                              258
 Val Leu Glu Gln Ala 
                  85





      <210> 415
      <211> 489
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(489)

      <400> 415
  atg aga ctg gaa gtc ctt acc ttg ctc ttg ttc tta gaa aga aag cat      48
  Met Arg Leu Glu Val Leu Thr Leu Leu Leu Phe Leu Glu Arg Lys His
    1               5                  10                  15

 tct ata ttt cat cat gaa gat gaa tta aac ctt gct gat tct gaa gtg       96
 Ser Ile Phe His His Glu Asp Glu Leu Asn Leu Ala Asp Ser Glu Val
              20                  25                  30

 gat aac caa aaa cga ggg aaa cga cat tat gaa gaa aaa caa aaa gaa      144
 Asp Asn Gln Lys Arg Gly Lys Arg His Tyr Glu Glu Lys Gln Lys Glu
          35                  40                  45

 cac ttg gat acc tta aat aaa aag aaa cga gaa ctg gat atg aaa gag      192
 His Leu Asp Thr Leu Asn Lys Lys Lys Arg Glu Leu Asp Met Lys Glu
      50                  55                  60

 aaa gaa cta gag gag aaa atg tca caa gca aga caa atc tgc cca gag      240
 Lys Glu Leu Glu Glu Lys Met Ser Gln Ala Arg Gln Ile Cys Pro Glu
  65                  70                  75                  80

 cgt ata gaa gta gaa aaa tct gca tca att ctg gac aaa gaa att aat      288
 Arg Ile Glu Val Glu Lys Ser Ala Ser Ile Leu Asp Lys Glu Ile Asn
                  85                  90                  95

 cga tta agg cag aag ata cag gca gaa cat gct agt cat gga gat cga      336
 Arg Leu Arg Gln Lys Ile Gln Ala Glu His Ala Ser His Gly Asp Arg
             100                 105                 110

 gag gaa ata atg aga gca cag gtt ctg aag aaa gag tat ctt gat tta      384
 Glu Glu Ile Met Arg Ala Gln Val Leu Lys Lys Glu Tyr Leu Asp Leu
         115                 120                 125

 aat tgc att tcc acc acc tat tta tgt gac ttt ggc aaa tta gct atc      432
 Asn Cys Ile Ser Thr Thr Tyr Leu Cys Asp Phe Gly Lys Leu Ala Ile
     130                 135                 140

 tct ctg aac ttt aat ttt ctc att cac aaa atg ggg att gtt ctg aag      480
 Ser Leu Asn Phe Asn Phe Leu Ile His Lys Met Gly Ile Val Leu Lys
 145                 150                 155                 160

 att aaa tga                                                          489
 Ile Lys 






      <210> 416
      <211> 771
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(771)

      <400> 416
  atg gcc ctc atc ccg ctt ccc atc tcc ttc tcg ctc cct tta gcc gcc      48
  Met Ala Leu Ile Pro Leu Pro Ile Ser Phe Ser Leu Pro Leu Ala Ala
    1               5                  10                  15

 ctc tgg gcc act gcg ttt gcc att ctt cag gtg gcc tgg ccc gac ctg       96
 Leu Trp Ala Thr Ala Phe Ala Ile Leu Gln Val Ala Trp Pro Asp Leu
              20                  25                  30

 ctt ggc ccc cat ccc ctc cgg gag ctg agg gac act ggc tct ggc cat      144
 Leu Gly Pro His Pro Leu Arg Glu Leu Arg Asp Thr Gly Ser Gly His
          35                  40                  45

 acc cag tgc gat ttc cac atg atg gct gca gga ccg gac ttt gta gta      192
 Thr Gln Cys Asp Phe His Met Met Ala Ala Gly Pro Asp Phe Val Val
      50                  55                  60

 atg agc agg cca ctc aac gaa ggc cca gat cat aac caa aat gca ggg      240
 Met Ser Arg Pro Leu Asn Glu Gly Pro Asp His Asn Gln Asn Ala Gly
  65                  70                  75                  80

 tct gtc agt tgc tac ttg cag aat cca att cac aag cgc gag ttc tgc      288
 Ser Val Ser Cys Tyr Leu Gln Asn Pro Ile His Lys Arg Glu Phe Cys
                  85                  90                  95

 ctc ctg gtg ggt gag cgt tct gct ctg gag cat cta agc aca gag tta      336
 Leu Leu Val Gly Glu Arg Ser Ala Leu Glu His Leu Ser Thr Glu Leu
             100                 105                 110

 gat gaa ttt aaa ggg tac act cgc cag cag ttt tgc cat gag agt aca      384
 Asp Glu Phe Lys Gly Tyr Thr Arg Gln Gln Phe Cys His Glu Ser Thr
         115                 120                 125

 ccg aac aaa gga gtc agg gtc att tat aac ccg acg cat cca ccc tac      432
 Pro Asn Lys Gly Val Arg Val Ile Tyr Asn Pro Thr His Pro Pro Tyr
     130                 135                 140

 tgc tgt gcc cag ttt cca ttg gct gca aca gga cct cac att ctg tat      480
 Cys Cys Ala Gln Phe Pro Leu Ala Ala Thr Gly Pro His Ile Leu Tyr
 145                 150                 155                 160

 tct agc aac tca gaa ctt ttt aaa aga ggc aaa ggc aga gga gaa caa      528
 Ser Ser Asn Ser Glu Leu Phe Lys Arg Gly Lys Gly Arg Gly Glu Gln
                 165                 170                 175

 agg aag gag gag gta acg tgg aat gct gag aaa gtg tgg gaa gtg agg      576
 Arg Lys Glu Glu Val Thr Trp Asn Ala Glu Lys Val Trp Glu Val Arg
             180                 185                 190

 agt gcc tct gtc cgg ctg ccc act gtt ggg gaa gtg agg agc gcc tct      624
 Ser Ala Ser Val Arg Leu Pro Thr Val Gly Glu Val Arg Ser Ala Ser
         195                 200                 205

 ccc cag ctt ctg ccc tgt ttg gga agt gag gag cat ctc tgc cca gct      672
 Pro Gln Leu Leu Pro Cys Leu Gly Ser Glu Glu His Leu Cys Pro Ala
     210                 215                 220

 gcc cac tgt tgg caa atg agg agt gcc tct gcc cgg cca cca ccc cat      720
 Ala His Cys Trp Gln Met Arg Ser Ala Ser Ala Arg Pro Pro Pro His
 225                 230                 235                 240

 ctg gga tgt gag gag cgc gtc tgc cca gct gcc gcc ctg ttt ggc aag      768
 Leu Gly Cys Glu Glu Arg Val Cys Pro Ala Ala Ala Leu Phe Gly Lys
                 245                 250                 255

 tga                                                                  771
 






      <210> 417
      <211> 924
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(924)

      <400> 417
  atg gct gcc atg gtc ctg ggc aca ctg tac tgc atc tcc tgc ttg gtg      48
  Met Ala Ala Met Val Leu Gly Thr Leu Tyr Cys Ile Ser Cys Leu Val
    1               5                  10                  15

 ctg gct ctg ggg gtg aag gaa cag tta ggg gga cag cag gcc att tcc       96
 Leu Ala Leu Gly Val Lys Glu Gln Leu Gly Gly Gln Gln Ala Ile Ser
              20                  25                  30

 gca gca gtt agt gga aat att ggt tct tgg agc agg cgc tgc gtg cct      144
 Ala Ala Val Ser Gly Asn Ile Gly Ser Trp Ser Arg Arg Cys Val Pro
          35                  40                  45

 cca gtg ctt ttc ccc tgg ccc ctg gat tct gat tcc gtt ggg cat aag      192
 Pro Val Leu Phe Pro Trp Pro Leu Asp Ser Asp Ser Val Gly His Lys
      50                  55                  60

 aag agt gac cca att cgt att atc aac ttt cac atg ctc aat aag aat      240
 Lys Ser Asp Pro Ile Arg Ile Ile Asn Phe His Met Leu Asn Lys Asn
  65                  70                  75                  80

 gta tgc atg gag atg ctt aac cgg ctg gaa gca cag agg aag ggc agg      288
 Val Cys Met Glu Met Leu Asn Arg Leu Glu Ala Gln Arg Lys Gly Arg
                  85                  90                  95

 aga acg aag caa gtc acc cgg caa aca cag ctg tat ccg gag gcc tcc      336
 Arg Thr Lys Gln Val Thr Arg Gln Thr Gln Leu Tyr Pro Glu Ala Ser
             100                 105                 110

 ggg ctt ccg gag gtc tcg ggg ctt ctg ggc ttc cgg tcc ctc ttc cgg      384
 Gly Leu Pro Glu Val Ser Gly Leu Leu Gly Phe Arg Ser Leu Phe Arg
         115                 120                 125

 agg cct ggg ttt ccg gga cgt cgc gcg ccg tgt ggg gcg cgc acg cag      432
 Arg Pro Gly Phe Pro Gly Arg Arg Ala Pro Cys Gly Ala Arg Thr Gln
     130                 135                 140

 ggc tgg gcg cga cgc gcc gag gta cta ggc aga gcc gtg gaa ccg ccg      480
 Gly Trp Ala Arg Arg Ala Glu Val Leu Gly Arg Ala Val Glu Pro Pro
 145                 150                 155                 160

 cca ggt cgc tgt tgg tcc acg ccg ccc gtc gcg ccg ccc gcc cgc tca      528
 Pro Gly Arg Cys Trp Ser Thr Pro Pro Val Ala Pro Pro Ala Arg Ser
                 165                 170                 175

 gcg tcc gcc gcc gcc atg gga gtg cag gtg gaa acc atc tcc cca gga      576
 Ala Ser Ala Ala Ala Met Gly Val Gln Val Glu Thr Ile Ser Pro Gly
             180                 185                 190

 gac ggg cgc acc ttc ccc aag cgc ggc cag acc tgc gtg gtg cac tac      624
 Asp Gly Arg Thr Phe Pro Lys Arg Gly Gln Thr Cys Val Val His Tyr
         195                 200                 205

 acc ggt gag agc cac tgg ctg gct tgg ctt tta atg ccc gcc ccc gcc      672
 Thr Gly Glu Ser His Trp Leu Ala Trp Leu Leu Met Pro Ala Pro Ala
     210                 215                 220

 ccc cca acc cac gct cct tct ggc tac tgt gtg gac aat ggg ctt ttg      720
 Pro Pro Thr His Ala Pro Ser Gly Tyr Cys Val Asp Asn Gly Leu Leu
 225                 230                 235                 240

 ggg gca aag gca gaa aca gga cac tgg ttg tat ccc agc ttg tgc cag      768
 Gly Ala Lys Ala Glu Thr Gly His Trp Leu Tyr Pro Ser Leu Cys Gln
                 245                 250                 255

 ttg tgt gac acc cac tta atc aca tac cac ccc acc cat ttc ggg gga      816
 Leu Cys Asp Thr His Leu Ile Thr Tyr His Pro Thr His Phe Gly Gly
             260                 265                 270

 tta ttg ttt agc ttt cgg act cga tta tgg gaa atc ctc tcc ttg gac      864
 Leu Leu Phe Ser Phe Arg Thr Arg Leu Trp Glu Ile Leu Ser Leu Asp
         275                 280                 285

 tca agg aac ccc aac atc act gcc acc acc caa ccc tgc cct gcg aag      912
 Ser Arg Asn Pro Asn Ile Thr Ala Thr Thr Gln Pro Cys Pro Ala Lys
     290                 295                 300

 att tct cct tag                                                      924
 Ile Ser Pro 
 305





      <210> 418
      <211> 129
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(129)

      <400> 418
  atg gcc ttt gag ttg aga gct cct ctg cac ttt gtg tat gcc atc ggc      48
  Met Ala Phe Glu Leu Arg Ala Pro Leu His Phe Val Tyr Ala Ile Gly
    1               5                  10                  15

 cag ctc ata gta ctt tgc aac tct gat caa tca aca tgc ttg cag att       96
 Gln Leu Ile Val Leu Cys Asn Ser Asp Gln Ser Thr Cys Leu Gln Ile
              20                  25                  30

 gtt aca atc ttg ccg ttt tcc cat cca cga taa                          129
 Val Thr Ile Leu Pro Phe Ser His Pro Arg 
          35                  40





      <210> 419
      <211> 627
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(627)

      <400> 419
  atg agc caa atg cat ttc tgt ctg tta caa att atg tac ggt gtg gtt      48
  Met Ser Gln Met His Phe Cys Leu Leu Gln Ile Met Tyr Gly Val Val
    1               5                  10                  15

 ttc tgt gat gaa cac agt gct gta cca ggg ccc tct tgc caa gac agc       96
 Phe Cys Asp Glu His Ser Ala Val Pro Gly Pro Ser Cys Gln Asp Ser
              20                  25                  30

 cag ctt ata gga gcc tgc att gac tgc tca ctc ctc ttc ctc caa aat      144
 Gln Leu Ile Gly Ala Cys Ile Asp Cys Ser Leu Leu Phe Leu Gln Asn
          35                  40                  45

 ccc tat cca tcc atc cat cca tcc atc cat cca tcc atc cat cca tcc      192
 Pro Tyr Pro Ser Ile His Pro Ser Ile His Pro Ser Ile His Pro Ser
      50                  55                  60

 atc caa ctt tcc atc tac cca tct atc ctt cca tct atc caa tcc act      240
 Ile Gln Leu Ser Ile Tyr Pro Ser Ile Leu Pro Ser Ile Gln Ser Thr
  65                  70                  75                  80

 tgc gtg ttg aac gtc tac tat gag cca ttg gct acc agg aat ccc act      288
 Cys Val Leu Asn Val Tyr Tyr Glu Pro Leu Ala Thr Arg Asn Pro Thr
                  85                  90                  95

 tcc acc caa att ata agg gtc acc gag tcc ctc atc aga atc ctg aaa      336
 Ser Thr Gln Ile Ile Arg Val Thr Glu Ser Leu Ile Arg Ile Leu Lys
             100                 105                 110

 gaa gga gaa acg gtg ggc aca ggc agc aca cct caa tca ctt gtg aat      384
 Glu Gly Glu Thr Val Gly Thr Gly Ser Thr Pro Gln Ser Leu Val Asn
         115                 120                 125

 aat ttc ctt ctg tct ttc ata aac ata gct atg att gaa atg acc ttt      432
 Asn Phe Leu Leu Ser Phe Ile Asn Ile Ala Met Ile Glu Met Thr Phe
     130                 135                 140

 cac gaa cag cag gga agg att gtg gaa gaa aat gag aaa ctc agt ctt      480
 His Glu Gln Gln Gly Arg Ile Val Glu Glu Asn Glu Lys Leu Ser Leu
 145                 150                 155                 160

 atg cag ctg gag cct ggc atc tgc tgc gga gaa ggg gtt gct gaa gtt      528
 Met Gln Leu Glu Pro Gly Ile Cys Cys Gly Glu Gly Val Ala Glu Val
                 165                 170                 175

 tat tct gac tcg ttt gaa gct ctt aaa ata ctg aaa gtg aaa gcg cta      576
 Tyr Ser Asp Ser Phe Glu Ala Leu Lys Ile Leu Lys Val Lys Ala Leu
             180                 185                 190

 cag acc cac gca gtc aag ccc cta gtg aga ttc ctt tcc aag agg ctg      624
 Gln Thr His Ala Val Lys Pro Leu Val Arg Phe Leu Ser Lys Arg Leu
         195                 200                 205

 tag                                                                  627
 






      <210> 420
      <211> 645
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(645)

      <400> 420
  atg gtg gtg aca gta atg atg gtg gtg atg gtg atg atg gtg acg ata      48
  Met Val Val Thr Val Met Met Val Val Met Val Met Met Val Thr Ile
    1               5                  10                  15

 gtg gtg atg atg atg gtg gtg ttg gtg ata gtg atg aag ttg ctg gta       96
 Val Val Met Met Met Val Val Leu Val Ile Val Met Lys Leu Leu Val
              20                  25                  30

 atg aca aca aat aca tgg gct gat agc tgt ata gca gtt gct ata tgc      144
 Met Thr Thr Asn Thr Trp Ala Asp Ser Cys Ile Ala Val Ala Ile Cys
          35                  40                  45

 cag gtg ctc tat gag gtg acc atg aat gcc tgt tat atg cca ggt ggc      192
 Gln Val Leu Tyr Glu Val Thr Met Asn Ala Cys Tyr Met Pro Gly Gly
      50                  55                  60

 atg tgg ccg gtc aat ggt gta cat tcc agg ggg gac gtc agg tac agg      240
 Met Trp Pro Val Asn Gly Val His Ser Arg Gly Asp Val Arg Tyr Arg
  65                  70                  75                  80

 tgc cag ttt gtg acg gat gaa agc acc gac agc cca cgc gtc ttc atc      288
 Cys Gln Phe Val Thr Asp Glu Ser Thr Asp Ser Pro Arg Val Phe Ile
                  85                  90                  95

 atg gag gcc tgt gcc cca gac tgt gcc cag cac aac agc tgg gcg gca      336
 Met Glu Ala Cys Ala Pro Asp Cys Ala Gln His Asn Ser Trp Ala Ala
             100                 105                 110

 agg gtg ggc cag ggt cga gca aat gac acg ttc cct ttg gct aag gaa      384
 Arg Val Gly Gln Gly Arg Ala Asn Asp Thr Phe Pro Leu Ala Lys Glu
         115                 120                 125

 gac acc cca gaa gca aaa tgc tcc atg cga cag cca ggc att cag gct      432
 Asp Thr Pro Glu Ala Lys Cys Ser Met Arg Gln Pro Gly Ile Gln Ala
     130                 135                 140

 aca agc tcg gtg gcg ggg agg cag ccg gga gcc ttc tca gag gag aag      480
 Thr Ser Ser Val Ala Gly Arg Gln Pro Gly Ala Phe Ser Glu Glu Lys
 145                 150                 155                 160

 ggt ccc gtg atc att cca cag atg ctt tca gag ctc tgg gct cag ggt      528
 Gly Pro Val Ile Ile Pro Gln Met Leu Ser Glu Leu Trp Ala Gln Gly
                 165                 170                 175

 aac cga cca att atg gtg ctg cca gag ggc ctg cat tta cta tac aca      576
 Asn Arg Pro Ile Met Val Leu Pro Glu Gly Leu His Leu Leu Tyr Thr
             180                 185                 190

 cgt cac aaa atc agg ctt ccc cgg gag gag cca tcg gac tct gtg cag      624
 Arg His Lys Ile Arg Leu Pro Arg Glu Glu Pro Ser Asp Ser Val Gln
         195                 200                 205

 agg gcc cat gtg aca ata taa                                          645
 Arg Ala His Val Thr Ile 
     210





      <210> 421
      <211> 810
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(810)

      <400> 421
  atg ccg cgt cag gac ctg ccg cgg tct cgg ctg ggc ttc ctg gga ctc      48
  Met Pro Arg Gln Asp Leu Pro Arg Ser Arg Leu Gly Phe Leu Gly Leu
    1               5                  10                  15

 ggt ggt tgt ggg ctg att gta aag cac gga atg act ctt aga aac tgg       96
 Gly Gly Cys Gly Leu Ile Val Lys His Gly Met Thr Leu Arg Asn Trp
              20                  25                  30

 gcg tca ttc ttt gtg gtt ttc caa gct tgg tct ctg atg ata ctc cag      144
 Ala Ser Phe Phe Val Val Phe Gln Ala Trp Ser Leu Met Ile Leu Gln
          35                  40                  45

 gtc tta gga gac atg ctg aat att tat tat gct tac att caa gca aca      192
 Val Leu Gly Asp Met Leu Asn Ile Tyr Tyr Ala Tyr Ile Gln Ala Thr
      50                  55                  60

 tta acc ctt aag gtt gat gta gct ccc cgt ctt ttt ttc cca gaa gga      240
 Leu Thr Leu Lys Val Asp Val Ala Pro Arg Leu Phe Phe Pro Glu Gly
  65                  70                  75                  80

 gga gca ctg aag gaa cac ttt tcc agt atg gat tct ttc cag ctc cga      288
 Gly Ala Leu Lys Glu His Phe Ser Ser Met Asp Ser Phe Gln Leu Arg
                  85                  90                  95

 gaa gct gga ggc aca cgg atc cct cgg cca gct ctc atc tat gga cgt      336
 Glu Ala Gly Gly Thr Arg Ile Pro Arg Pro Ala Leu Ile Tyr Gly Arg
             100                 105                 110

 gct gta gtc aca agg act gtg act aag gct cag tcc ctg agg agt gcc      384
 Ala Val Val Thr Arg Thr Val Thr Lys Ala Gln Ser Leu Arg Ser Ala
         115                 120                 125

 ttg gca tgg gct gct tta ggc tgt aaa cac cca gtt tta tcc act tta      432
 Leu Ala Trp Ala Ala Leu Gly Cys Lys His Pro Val Leu Ser Thr Leu
     130                 135                 140

 tgt gaa gaa agc caa caa ggg gca tgg act gag atg gct gct ccc cgg      480
 Cys Glu Glu Ser Gln Gln Gly Ala Trp Thr Glu Met Ala Ala Pro Arg
 145                 150                 155                 160

 tgg ggt gtg tgc tcg gcc tgc agt ccc cgc cct ccg gac tcc gtt cgc      528
 Trp Gly Val Cys Ser Ala Cys Ser Pro Arg Pro Pro Asp Ser Val Arg
                 165                 170                 175

 ctc cgc tct cag gtt tgc acc tcg tca ttg tct tct aat ttt gca tcc      576
 Leu Arg Ser Gln Val Cys Thr Ser Ser Leu Ser Ser Asn Phe Ala Ser
             180                 185                 190

 ctg gac tgc gtg acc tac aag gct ctc agc aca aca aga ctc tat gat      624
 Leu Asp Cys Val Thr Tyr Lys Ala Leu Ser Thr Thr Arg Leu Tyr Asp
         195                 200                 205

 tct gtc tat tgg aac aaa aag cca gtg agg caa gtg tat cat cct gtt      672
 Ser Val Tyr Trp Asn Lys Lys Pro Val Arg Gln Val Tyr His Pro Val
     210                 215                 220

 gac gaa ttc aca gca tta act ctg gga gtt ggg gac agt gtg tat tct      720
 Asp Glu Phe Thr Ala Leu Thr Leu Gly Val Gly Asp Ser Val Tyr Ser
 225                 230                 235                 240

 tcc tcc aga cac tct ctg ttt ctc ctg gat gga aag gtt ctg cta ctt      768
 Ser Ser Arg His Ser Leu Phe Leu Leu Asp Gly Lys Val Leu Leu Leu
                 245                 250                 255

 gtc ccg tgg tca ggc cca gcc aat gga acg gaa tgg aag tga              810
 Val Pro Trp Ser Gly Pro Ala Asn Gly Thr Glu Trp Lys 
             260                 265





      <210> 422
      <211> 804
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(804)

      <400> 422
  atg gtc ttg aac ttt tgg gcc tta atg atc ctc tcg ccc ggg tcg ggg      48
  Met Val Leu Asn Phe Trp Ala Leu Met Ile Leu Ser Pro Gly Ser Gly
    1               5                  10                  15

 gtt act att ttt agt tca acc ttc cta ctt acc cgg gaa aac cca aca       96
 Val Thr Ile Phe Ser Ser Thr Phe Leu Leu Thr Arg Glu Asn Pro Thr
              20                  25                  30

 agg ctt ccc ccc ttt tgc cca agt tgg ccc ccg cct aat gtc ctt ttt      144
 Arg Leu Pro Pro Phe Cys Pro Ser Trp Pro Pro Pro Asn Val Leu Phe
          35                  40                  45

 cca agc ctg ggg cgc ctt cga gca cca agt ttt cct cca aca ccg gct      192
 Pro Ser Leu Gly Arg Leu Arg Ala Pro Ser Phe Pro Pro Thr Pro Ala
      50                  55                  60

 aga gtt caa aac cac gaa ccc ggc act ttg cac ctg ttg ctc cga gcc      240
 Arg Val Gln Asn His Glu Pro Gly Thr Leu His Leu Leu Leu Arg Ala
  65                  70                  75                  80

 ttc tgg tct atc cca gtt ggt aga gtc cct gtg ctt acc tct gtg gct      288
 Phe Trp Ser Ile Pro Val Gly Arg Val Pro Val Leu Thr Ser Val Ala
                  85                  90                  95

 cag tcc tct ctg cat gaa gaa atc agt gat ttt tat gaa tac atg tct      336
 Gln Ser Ser Leu His Glu Glu Ile Ser Asp Phe Tyr Glu Tyr Met Ser
             100                 105                 110

 cca aga cct gag gag gag aag atg cgg atg gag gtg gtg aac agg atc      384
 Pro Arg Pro Glu Glu Glu Lys Met Arg Met Glu Val Val Asn Arg Ile
         115                 120                 125

 gag agt gta att aag gag ctc tgg ccc agc gct gac gtc cag ata ttt      432
 Glu Ser Val Ile Lys Glu Leu Trp Pro Ser Ala Asp Val Gln Ile Phe
     130                 135                 140

 gga agt ttt aaa act gga ctt tat tta cct act agt gac atc gac cta      480
 Gly Ser Phe Lys Thr Gly Leu Tyr Leu Pro Thr Ser Asp Ile Asp Leu
 145                 150                 155                 160

 gtg gtg ttt ggg aag tgg gag aac cta ccc ctc tgg act ctg gaa gaa      528
 Val Val Phe Gly Lys Trp Glu Asn Leu Pro Leu Trp Thr Leu Glu Glu
                 165                 170                 175

 gct ctt cgg aaa cac aaa gtc gca gat gag gat tcg gtg aaa gtt tta      576
 Ala Leu Arg Lys His Lys Val Ala Asp Glu Asp Ser Val Lys Val Leu
             180                 185                 190

 gac aaa gca act gta cct att att aaa tta aca gat tct ttt act gaa      624
 Asp Lys Ala Thr Val Pro Ile Ile Lys Leu Thr Asp Ser Phe Thr Glu
         195                 200                 205

 gtg aaa gtt gat atc agc ttt aat gta cag aat ggc gtg aga gca gct      672
 Val Lys Val Asp Ile Ser Phe Asn Val Gln Asn Gly Val Arg Ala Ala
     210                 215                 220

 gac ctc atc aaa gat ttt acc aag gct gca ggc tgt aca agc atg gct      720
 Asp Leu Ile Lys Asp Phe Thr Lys Ala Ala Gly Cys Thr Ser Met Ala
 225                 230                 235                 240

 cta gaa tct gct tct ggc gag ggc ctc agg aag ctt aca att acc gtg      768
 Leu Glu Ser Ala Ser Gly Glu Gly Leu Arg Lys Leu Thr Ile Thr Val
                 245                 250                 255

 gga gct gaa ggg gga gca ggc atg tta cat aaa taa                      804
 Gly Ala Glu Gly Gly Ala Gly Met Leu His Lys 
             260                 265





      <210> 423
      <211> 282
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(282)

      <400> 423
  atg gcg gcc ttt gct ggg aca gcc att ctg ctc atg gat ttt ggt gtt      48
  Met Ala Ala Phe Ala Gly Thr Ala Ile Leu Leu Met Asp Phe Gly Val
    1               5                  10                  15

 acc aac cgg gat gtg gac agg ggc tat ctg gcc gtg ctt act atc ttc       96
 Thr Asn Arg Asp Val Asp Arg Gly Tyr Leu Ala Val Leu Thr Ile Phe
              20                  25                  30

 act gtc ctg gag ttc ttc aca gcg gtc att gcc atg cac ttc ggg tgc      144
 Thr Val Leu Glu Phe Phe Thr Ala Val Ile Ala Met His Phe Gly Cys
          35                  40                  45

 caa gcc atc cat gcc cag gcc agt gca cct gtg atc ttc ctg cca aac      192
 Gln Ala Ile His Ala Gln Ala Ser Ala Pro Val Ile Phe Leu Pro Asn
      50                  55                  60

 gcc ttc agc gca gac ttc aac atc ccc agc ccg gca gcc tct gcg ccc      240
 Ala Phe Ser Ala Asp Phe Asn Ile Pro Ser Pro Ala Ala Ser Ala Pro
  65                  70                  75                  80

 cct gcc tat gac aat gtg gca tat gcc caa gga gtc gtc tga              282
 Pro Ala Tyr Asp Asn Val Ala Tyr Ala Gln Gly Val Val 
                  85                  90





      <210> 424
      <211> 387
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(387)

      <400> 424
  atg ctt tgt att gct att cat att ctg ttt tta tta aat agg ttt att      48
  Met Leu Cys Ile Ala Ile His Ile Leu Phe Leu Leu Asn Arg Phe Ile
    1               5                  10                  15

 gct gac aat caa atg aat cat gcc tgt atg ctg ttt gta gaa aat tat       96
 Ala Asp Asn Gln Met Asn His Ala Cys Met Leu Phe Val Glu Asn Tyr
              20                  25                  30

 gga cag aaa ata att aag aag aat tta tgt cga aac ttc atg ctt cat      144
 Gly Gln Lys Ile Ile Lys Lys Asn Leu Cys Arg Asn Phe Met Leu His
          35                  40                  45

 cta gtc agc atg cat gac ttt aat ctt att agc ata atg tca ata gat      192
 Leu Val Ser Met His Asp Phe Asn Leu Ile Ser Ile Met Ser Ile Asp
      50                  55                  60

 aaa gct gtt acc aag ctc cgt gaa atg cag caa aaa tta gaa aag ggg      240
 Lys Ala Val Thr Lys Leu Arg Glu Met Gln Gln Lys Leu Glu Lys Gly
  65                  70                  75                  80

 gaa tct gct tcc cct gca aac gaa gaa ata act gaa gaa caa aat ggg      288
 Glu Ser Ala Ser Pro Ala Asn Glu Glu Ile Thr Glu Glu Gln Asn Gly
                  85                  90                  95

 aca gca aat gga ttt agt gaa att aac tca aaa gag aaa gct ttg gaa      336
 Thr Ala Asn Gly Phe Ser Glu Ile Asn Ser Lys Glu Lys Ala Leu Glu
             100                 105                 110

 aca gat agt gtc tca ggg gtt tca aaa cag agc aaa aaa caa aaa ctc      384
 Thr Asp Ser Val Ser Gly Val Ser Lys Gln Ser Lys Lys Gln Lys Leu
         115                 120                 125

 tga                                                                  387
 






      <210> 425
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 425
  atg ctg ttt gca gcc ttt ggc agg ccc cac gtt ggc gca gtg cac ctg      48
  Met Leu Phe Ala Ala Phe Gly Arg Pro His Val Gly Ala Val His Leu
    1               5                  10                  15

 gtt gtt ggt tgt gct tgg aag gag aaa tgg ctg gac gtg aga gca cac       96
 Val Val Gly Cys Ala Trp Lys Glu Lys Trp Leu Asp Val Arg Ala His
              20                  25                  30

 acc gat tca ccg acc gta gcc aat gat ttg cct gga gag tca ggg act      144
 Thr Asp Ser Pro Thr Val Ala Asn Asp Leu Pro Gly Glu Ser Gly Thr
          35                  40                  45

 tgg aag gaa cat gat tgg aaa att agt gat aag gaa acc gag gga act      192
 Trp Lys Glu His Asp Trp Lys Ile Ser Asp Lys Glu Thr Glu Gly Thr
      50                  55                  60

 gag aga aga gac act cta gat cgg gat ttg cct tcc ctg tac gtc acg      240
 Glu Arg Arg Asp Thr Leu Asp Arg Asp Leu Pro Ser Leu Tyr Val Thr
  65                  70                  75                  80

 ctc ctg cca aaa cta gcg tcc gtg gac tca cag aat gcc gta cct act      288
 Leu Leu Pro Lys Leu Ala Ser Val Asp Ser Gln Asn Ala Val Pro Thr
                  85                  90                  95

 gtc acg gta tgc cac acc gca ctg ctt ctg tct gag gaa ctc cct tca      336
 Val Thr Val Cys His Thr Ala Leu Leu Leu Ser Glu Glu Leu Pro Ser
             100                 105                 110

 cag caa aga aag tat ggt aac gag ccc atg ctc atg gaa ttc ccc ggt      384
 Gln Gln Arg Lys Tyr Gly Asn Glu Pro Met Leu Met Glu Phe Pro Gly
         115                 120                 125

 acg acc atg ttg ccc acc atc ttg aag cag ctg gtt tga                  423
 Thr Thr Met Leu Pro Thr Ile Leu Lys Gln Leu Val 
     130                 135                 140





      <210> 426
      <211> 750
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(750)

      <400> 426
  atg aca tgc cac ctg ggg tgg ctg gca gag atc aga ctg tgg cta cag      48
  Met Thr Cys His Leu Gly Trp Leu Ala Glu Ile Arg Leu Trp Leu Gln
    1               5                  10                  15

 gtc tgg gtt ggg gca tct ctg cca aat gac ttg atg cct gac cac ttc       96
 Val Trp Val Gly Ala Ser Leu Pro Asn Asp Leu Met Pro Asp His Phe
              20                  25                  30

 aga gac atc ggg ctt ggc tac cca aac cac att ttg gct cag cca ggc      144
 Arg Asp Ile Gly Leu Gly Tyr Pro Asn His Ile Leu Ala Gln Pro Gly
          35                  40                  45

 cag ctc cag cga ttc aag cgc tcc ctc tcc ctc aag acc atc ctc cga      192
 Gln Leu Gln Arg Phe Lys Arg Ser Leu Ser Leu Lys Thr Ile Leu Arg
      50                  55                  60

 agt aag agc ttg gag aac ttc ttc ctt cgc tcg ggc tct gag ctc aag      240
 Ser Lys Ser Leu Glu Asn Phe Phe Leu Arg Ser Gly Ser Glu Leu Lys
  65                  70                  75                  80

 tgc ccc acc gag gtg ctg ctg acg ccc cca acc cca ctg ccc cct ccc      288
 Cys Pro Thr Glu Val Leu Leu Thr Pro Pro Thr Pro Leu Pro Pro Pro
                  85                  90                  95

 tcc cca cca ccc aca gcc tcg gac agg ggc ctg gct acc cca tcc ccc      336
 Ser Pro Pro Pro Thr Ala Ser Asp Arg Gly Leu Ala Thr Pro Ser Pro
             100                 105                 110

 tcc cca tgc cca gtc cca cgc ccc ctg gca gcg ctc aaa cca gtg agg      384
 Ser Pro Cys Pro Val Pro Arg Pro Leu Ala Ala Leu Lys Pro Val Arg
         115                 120                 125

 ctg cac agc ttc cag gaa cat gtc ttc aag cga gct agc cct tgt gag      432
 Leu His Ser Phe Gln Glu His Val Phe Lys Arg Ala Ser Pro Cys Glu
     130                 135                 140

 ctg tgc cac cag ctc atc gta gga aac tcc aaa cag ggc ttg cga tgt      480
 Leu Cys His Gln Leu Ile Val Gly Asn Ser Lys Gln Gly Leu Arg Cys
 145                 150                 155                 160

 aag atg tgc aaa gtc agc gtc cac ctc tgg tgc tct gag gag atc tcc      528
 Lys Met Cys Lys Val Ser Val His Leu Trp Cys Ser Glu Glu Ile Ser
                 165                 170                 175

 cac cag caa tgc cca ggc aag acg tcc acc tcc ttc cgc cgc aac ttc      576
 His Gln Gln Cys Pro Gly Lys Thr Ser Thr Ser Phe Arg Arg Asn Phe
             180                 185                 190

 agt tcc cct ctc ctg gtg cat gag ccg cca cca gtc tgt gcc aca agc      624
 Ser Ser Pro Leu Leu Val His Glu Pro Pro Pro Val Cys Ala Thr Ser
         195                 200                 205

 aaa gag tcc cca ccc act gat gtt gtt acc ctg tgc cgc tgt gct cag      672
 Lys Glu Ser Pro Pro Thr Asp Val Val Thr Leu Cys Arg Cys Ala Gln
     210                 215                 220

 gtc tcc agg tct tgg cgt ctg aac ttc agc aga gat ggg ggc tca gtc      720
 Val Ser Arg Ser Trp Arg Leu Asn Phe Ser Arg Asp Gly Gly Ser Val
 225                 230                 235                 240

 ctc aca ccc aaa gtc ccc aaa ctt ctc tga                              750
 Leu Thr Pro Lys Val Pro Lys Leu Leu 
                 245





      <210> 427
      <211> 1191
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1191)

      <400> 427
  atg cag ctt ctc agg gag tgg cca ggc gtg atc ctc agg gcg gga acc      48
  Met Gln Leu Leu Arg Glu Trp Pro Gly Val Ile Leu Arg Ala Gly Thr
    1               5                  10                  15

 acg ctc tca gtc ctg ccc tgg gcc cta cag gaa cgc tgg cgg gtg act       96
 Thr Leu Ser Val Leu Pro Trp Ala Leu Gln Glu Arg Trp Arg Val Thr
              20                  25                  30

 gcc gag cag tcc aag gcg gag tcc atg cag cgc gcc cta gag gag caa      144
 Ala Glu Gln Ser Lys Ala Glu Ser Met Gln Arg Ala Leu Glu Glu Gln
          35                  40                  45

 agg aag gtc acg gcc cag cag atg gcc atg gaa agg gcg gag ctg gaa      192
 Arg Lys Val Thr Ala Gln Gln Met Ala Met Glu Arg Ala Glu Leu Glu
      50                  55                  60

 cgg gcc aag agc gcc ttg ctg gag gag cag aag tct gtc atg ctc aag      240
 Arg Ala Lys Ser Ala Leu Leu Glu Glu Gln Lys Ser Val Met Leu Lys
  65                  70                  75                  80

 tgc ggg gag gag cgg cgg cgc ctg gct gcc gag tgg gcg gag ttc tcc      288
 Cys Gly Glu Glu Arg Arg Arg Leu Ala Ala Glu Trp Ala Glu Phe Ser
                  85                  90                  95

 gcg cag caa aag ctg agt aag gag cgg gcc gag cgc gag gcc gag cgg      336
 Ala Gln Gln Lys Leu Ser Lys Glu Arg Ala Glu Arg Glu Ala Glu Arg
             100                 105                 110

 gca ttg cag gtg gac acc cag cgg gag ggc acc ctc atc agc ctg gcc      384
 Ala Leu Gln Val Asp Thr Gln Arg Glu Gly Thr Leu Ile Ser Leu Ala
         115                 120                 125

 aag gag cag gct gag ctg aag atc agg gcc agc gag ctc cgg gcc gag      432
 Lys Glu Gln Ala Glu Leu Lys Ile Arg Ala Ser Glu Leu Arg Ala Glu
     130                 135                 140

 gag aag cag ctg gca gcg gag aga gca gcc ctg gag cag gag cgg cag      480
 Glu Lys Gln Leu Ala Ala Glu Arg Ala Ala Leu Glu Gln Glu Arg Gln
 145                 150                 155                 160

 gag ctg cgg ctg gag aag gag agg atc aac gcc acc gcc ctg cgt gtc      528
 Glu Leu Arg Leu Glu Lys Glu Arg Ile Asn Ala Thr Ala Leu Arg Val
                 165                 170                 175

 aag ctc cgc gcc gag gag gtg gag agc atg agc aag gtg gcc tcc gag      576
 Lys Leu Arg Ala Glu Glu Val Glu Ser Met Ser Lys Val Ala Ser Glu
             180                 185                 190

 aag tac gag gag ggg gag cgg gca ttg cgc gag gcc cag cag gtg cag      624
 Lys Tyr Glu Glu Gly Glu Arg Ala Leu Arg Glu Ala Gln Gln Val Gln
         195                 200                 205

 gca gag cag cag gcc cgg ttg cag gcg gtg cag caa cag cag gag cgg      672
 Ala Glu Gln Gln Ala Arg Leu Gln Ala Val Gln Gln Gln Gln Glu Arg
     210                 215                 220

 ctg cgg aag cag agg cag cgc atg cgg gag gga gag agg ggg gtc cct      720
 Leu Arg Lys Gln Arg Gln Arg Met Arg Glu Gly Glu Arg Gly Val Pro
 225                 230                 235                 240

 cca gcc aag gct cct cag tac tgg gat gcg gac atc ttc aga ggt cac      768
 Pro Ala Lys Ala Pro Gln Tyr Trp Asp Ala Asp Ile Phe Arg Gly His
                 245                 250                 255

 acc gcc cct ttc tgg ctt tct gtg gtt ttg gag gct cag aag cgg aaa      816
 Thr Ala Pro Phe Trp Leu Ser Val Val Leu Glu Ala Gln Lys Arg Lys
             260                 265                 270

 tgc act cga ggt gtg tat aaa cac tct aac agc agg aat tgc tca gaa      864
 Cys Thr Arg Gly Val Tyr Lys His Ser Asn Ser Arg Asn Cys Ser Glu
         275                 280                 285

 cag gcc ttg cag ctg tgt ctg ggg aaa ctg aac ttg aca gag cca gga      912
 Gln Ala Leu Gln Leu Cys Leu Gly Lys Leu Asn Leu Thr Glu Pro Gly
     290                 295                 300

 ggt ccc agc ggg aac ttc agg gtg ggg ccc atc tct ata gca acc aga      960
 Gly Pro Ser Gly Asn Phe Arg Val Gly Pro Ile Ser Ile Ala Thr Arg
 305                 310                 315                 320

 aac agc ccc aga cac gct ctg gcc ctg ctt ctg atg agg gag cgg gca     1008
 Asn Ser Pro Arg His Ala Leu Ala Leu Leu Leu Met Arg Glu Arg Ala
                 325                 330                 335

 att tgt gtt ctt gaa ata ccc acg gcc aaa aag gac tca tcc aaa ata     1056
 Ile Cys Val Leu Glu Ile Pro Thr Ala Lys Lys Asp Ser Ser Lys Ile
             340                 345                 350

 gcc cac ttc cac gtc acc aaa cat cac caa cgc ctc aca ggg cat ctg     1104
 Ala His Phe His Val Thr Lys His His Gln Arg Leu Thr Gly His Leu
         355                 360                 365

 cca ctc cgc agc aga gca acc aac ggt gag tgg cag aaa gtt acc aat     1152
 Pro Leu Arg Ser Arg Ala Thr Asn Gly Glu Trp Gln Lys Val Thr Asn
     370                 375                 380

 gac tta cca gga gtt tta ttt ttc tca ctg gcg tat tag                 1191
 Asp Leu Pro Gly Val Leu Phe Phe Ser Leu Ala Tyr 
 385                 390                 395





      <210> 428
      <211> 642
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(642)

      <400> 428
  atg agg gtc atc gtc gcg tca tct caa atg cgg tgg ctc gtg cta acg      48
  Met Arg Val Ile Val Ala Ser Ser Gln Met Arg Trp Leu Val Leu Thr
    1               5                  10                  15

 cgt gct cac gtg atg aaa tcc gca act tgc tgt tcg tgc gta cgt ctg       96
 Arg Ala His Val Met Lys Ser Ala Thr Cys Cys Ser Cys Val Arg Leu
              20                  25                  30

 aca gtc ctc gat aca tca acg ctc atc gcg tgt cca cag tat gtg ttt      144
 Thr Val Leu Asp Thr Ser Thr Leu Ile Ala Cys Pro Gln Tyr Val Phe
          35                  40                  45

 gtc cac tat gtg ttt cat gtc gcc gaa tct gta tgt cgc cac cgt act      192
 Val His Tyr Val Phe His Val Ala Glu Ser Val Cys Arg His Arg Thr
      50                  55                  60

 cta caa cat atg cac att ttc tgt tca atg cat ttg ata cag acc aca      240
 Leu Gln His Met His Ile Phe Cys Ser Met His Leu Ile Gln Thr Thr
  65                  70                  75                  80

 atg gag ctc ttt aag acc act gaa cta aaa caa ttc tca gtc agc aga      288
 Met Glu Leu Phe Lys Thr Thr Glu Leu Lys Gln Phe Ser Val Ser Arg
                  85                  90                  95

 gcc ctg ctt tct aat cca ggt cta gaa agt tcc aaa cgt caa cgg ggt      336
 Ala Leu Leu Ser Asn Pro Gly Leu Glu Ser Ser Lys Arg Gln Arg Gly
             100                 105                 110

 cca gcg gcc cta gca aca gat cag gaa gca agc cgg ctt ggc aga gag      384
 Pro Ala Ala Leu Ala Thr Asp Gln Glu Ala Ser Arg Leu Gly Arg Glu
         115                 120                 125

 cgc aga cag gac acc tgt acc cgc ggt tca cgg ctc cgg gga ccc gtt      432
 Arg Arg Gln Asp Thr Cys Thr Arg Gly Ser Arg Leu Arg Gly Pro Val
     130                 135                 140

 cct acc gcg cct ctc tcc cgc cgc gat ccg cac acc agc tgc ccc cca      480
 Pro Thr Ala Pro Leu Ser Arg Arg Asp Pro His Thr Ser Cys Pro Pro
 145                 150                 155                 160

 ccg ggg ggg gct tat gac cgg cac tcg gtc ggc caa caa ccg cgg cta      528
 Pro Gly Gly Ala Tyr Asp Arg His Ser Val Gly Gln Gln Pro Arg Leu
                 165                 170                 175

 ccg cca ccg agc gcc tgc gtt tgg gga aat gag gct ccg cgc ggc ccg      576
 Pro Pro Pro Ser Ala Cys Val Trp Gly Asn Glu Ala Pro Arg Gly Pro
             180                 185                 190

 ccc ctg aac ctg gtc gcg ccg cgc aat gac gtc aga cgc acg ctg cgt      624
 Pro Leu Asn Leu Val Ala Pro Arg Asn Asp Val Arg Arg Thr Leu Arg
         195                 200                 205

 cgt cta aac caa tgg taa                                              642
 Arg Leu Asn Gln Trp 
     210





      <210> 429
      <211> 795
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(795)

      <400> 429
  atg gcg ccg gcg tcg cgg ttg ctc gcg ctc tgg gcg ctg gcg gct gtg      48
  Met Ala Pro Ala Ser Arg Leu Leu Ala Leu Trp Ala Leu Ala Ala Val
    1               5                  10                  15

 gct cta ccc ggc tcc ggg gcg gag ggc gac ggc ggg tgg cgc ccg ggc       96
 Ala Leu Pro Gly Ser Gly Ala Glu Gly Asp Gly Gly Trp Arg Pro Gly
              20                  25                  30

 ggg ccg ggg gcc gtg gcg gag gag gag cgc tgc acg gtg gag cgt cgg      144
 Gly Pro Gly Ala Val Ala Glu Glu Glu Arg Cys Thr Val Glu Arg Arg
          35                  40                  45

 gcc gac ctc acc tac gcg gag ttc gtg cag cag tac gcc ttc gtc agg      192
 Ala Asp Leu Thr Tyr Ala Glu Phe Val Gln Gln Tyr Ala Phe Val Arg
      50                  55                  60

 ccc gtc atc ctg cag gga ctc acg gac aac tcg agg ttc cgg gcc ctg      240
 Pro Val Ile Leu Gln Gly Leu Thr Asp Asn Ser Arg Phe Arg Ala Leu
  65                  70                  75                  80

 tgc tcc cgc gac agg ttg ctg gct tcg ttt ggg gac aga gtg gtc cgg      288
 Cys Ser Arg Asp Arg Leu Leu Ala Ser Phe Gly Asp Arg Val Val Arg
                  85                  90                  95

 ctg agc acc gcc aac acc tac tcc tac cac aaa gtg gac ttg ccc ttc      336
 Leu Ser Thr Ala Asn Thr Tyr Ser Tyr His Lys Val Asp Leu Pro Phe
             100                 105                 110

 cag gag tat gtg gag cag ctg ctg cac ccc cag gac ccc acc tcc ctg      384
 Gln Glu Tyr Val Glu Gln Leu Leu His Pro Gln Asp Pro Thr Ser Leu
         115                 120                 125

 ggc aat gac acc ctg tac ttc ttc ggg gac aac aac ttc acc gag tgg      432
 Gly Asn Asp Thr Leu Tyr Phe Phe Gly Asp Asn Asn Phe Thr Glu Trp
     130                 135                 140

 gcc tct ctc ttt cgg cac tac tcc cca ccc cca ttt ggc ctg ctg gga      480
 Ala Ser Leu Phe Arg His Tyr Ser Pro Pro Pro Phe Gly Leu Leu Gly
 145                 150                 155                 160

 acc gct cca gct tac agc ttt gga atc gca gga gct ggc tcg ggg gtg      528
 Thr Ala Pro Ala Tyr Ser Phe Gly Ile Ala Gly Ala Gly Ser Gly Val
                 165                 170                 175

 ccc ttc cac tgg cat gga ccc ggg tac tca gaa gtg atc tac ggt cgt      576
 Pro Phe His Trp His Gly Pro Gly Tyr Ser Glu Val Ile Tyr Gly Arg
             180                 185                 190

 aag cgc tgg ttc ctt tac cca cct gag aag acg cca gag ttc cac ccc      624
 Lys Arg Trp Phe Leu Tyr Pro Pro Glu Lys Thr Pro Glu Phe His Pro
         195                 200                 205

 aac aag acc acg ctg gcc tgg ctc cgg gac aca tac cca gcc ctg cca      672
 Asn Lys Thr Thr Leu Ala Trp Leu Arg Asp Thr Tyr Pro Ala Leu Pro
     210                 215                 220

 ccg tct gca cgg ccc ctg gag tgt acc atc cgg gct ggt gag gtg ctg      720
 Pro Ser Ala Arg Pro Leu Glu Cys Thr Ile Arg Ala Gly Glu Val Leu
 225                 230                 235                 240

 tac ttc ccc gac cgc tgg tgg cat gct acg ctc aac ctt gac acc agc      768
 Tyr Phe Pro Asp Arg Trp Trp His Ala Thr Leu Asn Leu Asp Thr Ser
                 245                 250                 255

 gtc ttc atc tcc acc ttc ctc ggc tag                                  795
 Val Phe Ile Ser Thr Phe Leu Gly 
             260





      <210> 430
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 430
  atg gca ttg gac ttt gtc aat gtt ctc ctc tgc cag tta gca gag gtg      48
  Met Ala Leu Asp Phe Val Asn Val Leu Leu Cys Gln Leu Ala Glu Val
    1               5                  10                  15

 aca ctg ggg gtg cta cgg gaa gaa ggg gca tcc ctc ctg gtt gca ctg       96
 Thr Leu Gly Val Leu Arg Glu Glu Gly Ala Ser Leu Leu Val Ala Leu
              20                  25                  30

 ggc agc gct ctc ttc cca tct gca gct gcc gtg ggc aag cag ggt tcc      144
 Gly Ser Ala Leu Phe Pro Ser Ala Ala Ala Val Gly Lys Gln Gly Ser
          35                  40                  45

 atg ggg ggc tgc ttc cac tcc tcc agt gag agc gag cct cgg gac cag      192
 Met Gly Gly Cys Phe His Ser Ser Ser Glu Ser Glu Pro Arg Asp Gln
      50                  55                  60

 agg aac ggc cca aac aac cct gag tgt gat gag aaa cca ttg tta ccg      240
 Arg Asn Gly Pro Asn Asn Pro Glu Cys Asp Glu Lys Pro Leu Leu Pro
  65                  70                  75                  80

 tgg ctc taa                                                          249
 Trp Leu 






      <210> 431
      <211> 132
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(132)

      <400> 431
  atg att gcc atc tac ggc acc aat ttc tgc acc tcg gcc agg aat gcc      48
  Met Ile Ala Ile Tyr Gly Thr Asn Phe Cys Thr Ser Ala Arg Asn Ala
    1               5                  10                  15

 ttc ttc ctg ctc atg aga aac atc atc agg tcg gga atc att atc atc       96
 Phe Phe Leu Leu Met Arg Asn Ile Ile Arg Ser Gly Ile Ile Ile Ile
              20                  25                  30

 ttc ctc ctg cca ccc gcc tct tcc cct agt ccc tga                      132
 Phe Leu Leu Pro Pro Ala Ser Ser Pro Ser Pro 
          35                  40





      <210> 432
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 432
  atg gct gca aat act tgg ctg ttg gcc tct atg tgg ctt ggg ccc ctc      48
  Met Ala Ala Asn Thr Trp Leu Leu Ala Ser Met Trp Leu Gly Pro Leu
    1               5                  10                  15

 tca aca tgc cca aac aag aca tct gca gac ata ggt gat atc atg tcc       96
 Ser Thr Cys Pro Asn Lys Thr Ser Ala Asp Ile Gly Asp Ile Met Ser
              20                  25                  30

 tca gtg aat tat atc aca aga ctc agt ttg acc cat att agt aat ggc      144
 Ser Val Asn Tyr Ile Thr Arg Leu Ser Leu Thr His Ile Ser Asn Gly
          35                  40                  45

 agt ttt ggc ctc ttg gtt aaa gta aca ttc acc aaa tta tcc agt gta      192
 Ser Phe Gly Leu Leu Val Lys Val Thr Phe Thr Lys Leu Ser Ser Val
      50                  55                  60

 aag cac ctg agt gga ttc cct gag ctg tca gcc tct ggc ttc tcc tca      240
 Lys His Leu Ser Gly Phe Pro Glu Leu Ser Ala Ser Gly Phe Ser Ser
  65                  70                  75                  80

 aag aga act ttg gtg ttt ata tta cca ctc gca gcc cct ttc tca gtt      288
 Lys Arg Thr Leu Val Phe Ile Leu Pro Leu Ala Ala Pro Phe Ser Val
                  85                  90                  95

 ggc ctt gag gct tgc cca tta gct ggt aaa cgt ttg aaa ggg tca gtg      336
 Gly Leu Glu Ala Cys Pro Leu Ala Gly Lys Arg Leu Lys Gly Ser Val
             100                 105                 110

 tgt cca gaa ctg gaa ttt cca ctt tgg aaa aag cac aga gtg ttc tcg      384
 Cys Pro Glu Leu Glu Phe Pro Leu Trp Lys Lys His Arg Val Phe Ser
         115                 120                 125

 cag tct ttg cct tat aaa act cat gca ttc aat gaa gag cgg ctg caa      432
 Gln Ser Leu Pro Tyr Lys Thr His Ala Phe Asn Glu Glu Arg Leu Gln
     130                 135                 140

 gag tga                                                              438
 Glu 
 145





      <210> 433
      <211> 567
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(567)

      <400> 433
  atg ctc cta acc act gtg cta tac ttc cca ctg gat gcc aag gcc tgt      48
  Met Leu Leu Thr Thr Val Leu Tyr Phe Pro Leu Asp Ala Lys Ala Cys
    1               5                  10                  15

 ttc caa ctc ttt tat ctc att caa tcc tcc ctc tgt aag gga cgg acg       96
 Phe Gln Leu Phe Tyr Leu Ile Gln Ser Ser Leu Cys Lys Gly Arg Thr
              20                  25                  30

 ctc tat tcc gtt gtg agg gat gcc aaa atc gtt ttg gat gtc aac aaa      144
 Leu Tyr Ser Val Val Arg Asp Ala Lys Ile Val Leu Asp Val Asn Lys
          35                  40                  45

 acc agg cag att gct caa gaa att gtg aag ggc atg ggc tac ctc cac      192
 Thr Arg Gln Ile Ala Gln Glu Ile Val Lys Gly Met Gly Tyr Leu His
      50                  55                  60

 gcc aag gga atc cta cac aag gac ctc aag tca aag aac gtc ttc tat      240
 Ala Lys Gly Ile Leu His Lys Asp Leu Lys Ser Lys Asn Val Phe Tyr
  65                  70                  75                  80

 gac aac ggc aaa gtg gtc atc acg gac ttt gga ctc ttc agc att tct      288
 Asp Asn Gly Lys Val Val Ile Thr Asp Phe Gly Leu Phe Ser Ile Ser
                  85                  90                  95

 ggg gtg ctg cag gct ggc agg cgg gag gac aaa ctg cgc atc cag aat      336
 Gly Val Leu Gln Ala Gly Arg Arg Glu Asp Lys Leu Arg Ile Gln Asn
             100                 105                 110

 ggc tgg cta tgc cac ctg gca cca gag atc atc cgc cag ctg tcc ccc      384
 Gly Trp Leu Cys His Leu Ala Pro Glu Ile Ile Arg Gln Leu Ser Pro
         115                 120                 125

 gac aca gag gag gat aag ctc ccc ttc tcc aag cac tct gac gtc ttt      432
 Asp Thr Glu Glu Asp Lys Leu Pro Phe Ser Lys His Ser Asp Val Phe
     130                 135                 140

 gcc ctt ggg gaa atg ctg gca gcc ttc act gaa tca gag cct gtg ggt      480
 Ala Leu Gly Glu Met Leu Ala Ala Phe Thr Glu Ser Glu Pro Val Gly
 145                 150                 155                 160

 atg aaa gct gag aat gga cat cag cag cac cca gag gag gtg gaa gca      528
 Met Lys Ala Glu Asn Gly His Gln Gln His Pro Glu Glu Val Glu Ala
                 165                 170                 175

 ata gag ctt gat gat gga ttg aat ttg ggt ggt gcc tag                  567
 Ile Glu Leu Asp Asp Gly Leu Asn Leu Gly Gly Ala 
             180                 185





      <210> 434
      <211> 1293
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1293)

      <400> 434
  atg ctg gac ctg tac gcg ggg gct ctg ttt gtg cac atc tgc ctg ggc      48
  Met Leu Asp Leu Tyr Ala Gly Ala Leu Phe Val His Ile Cys Leu Gly
    1               5                  10                  15

 tgg aac ttc tac ctc tcc acc atc ctc acg ctc ggc atc aca gcc ctg       96
 Trp Asn Phe Tyr Leu Ser Thr Ile Leu Thr Leu Gly Ile Thr Ala Leu
              20                  25                  30

 tac acc atc gca ggg ggc ctg gct gct gta atc tac acg gac gcc ctg      144
 Tyr Thr Ile Ala Gly Gly Leu Ala Ala Val Ile Tyr Thr Asp Ala Leu
          35                  40                  45

 cag acg ctc atc atg gtg gtg ggg gct gtc atc ctg aca atc aaa ggg      192
 Gln Thr Leu Ile Met Val Val Gly Ala Val Ile Leu Thr Ile Lys Gly
      50                  55                  60

 act gcc ctg gct ggt aga ggc tac cca ccc tgc tgc ccc gct gtt acc      240
 Thr Ala Leu Ala Gly Arg Gly Tyr Pro Pro Cys Cys Pro Ala Val Thr
  65                  70                  75                  80

 agc tct ggc cct ggc aag gag ctg act cag gaa ctc agg gcc agc cac      288
 Ser Ser Gly Pro Gly Lys Glu Leu Thr Gln Glu Leu Arg Ala Ser His
                  85                  90                  95

 acc cgc att ggc tca gcg ctt gat gct ttt gac cag atc ggt ggt tac      336
 Thr Arg Ile Gly Ser Ala Leu Asp Ala Phe Asp Gln Ile Gly Gly Tyr
             100                 105                 110

 ggg cag ctg gag gca gcc tac gcc cag gcc att ccc tcc agg acc att      384
 Gly Gln Leu Glu Ala Ala Tyr Ala Gln Ala Ile Pro Ser Arg Thr Ile
         115                 120                 125

 gcc aac acc acc tgc cac ctg cca cgt aca gac gcc atg cac atg ttt      432
 Ala Asn Thr Thr Cys His Leu Pro Arg Thr Asp Ala Met His Met Phe
     130                 135                 140

 cga gac ccc cac aca ggg gac ctg ccg tgg acc ggg atg acc ttt ggc      480
 Arg Asp Pro His Thr Gly Asp Leu Pro Trp Thr Gly Met Thr Phe Gly
 145                 150                 155                 160

 ctg acc atc atg gcc acc tgg tac tgg tgc acc gac cag gtg ctt cga      528
 Leu Thr Ile Met Ala Thr Trp Tyr Trp Cys Thr Asp Gln Val Leu Arg
                 165                 170                 175

 ctg aga cag ttt gga gta tgg gat tcc gaa ggg act cgg atg ctc ctc      576
 Leu Arg Gln Phe Gly Val Trp Asp Ser Glu Gly Thr Arg Met Leu Leu
             180                 185                 190

 ggt ggc cct gcc atc ggt cat ggg gcg ggc att ttg ggc cag tct tgg      624
 Gly Gly Pro Ala Ile Gly His Gly Ala Gly Ile Leu Gly Gln Ser Trp
         195                 200                 205

 gct gcc ggg atc cgg aag cag gcg ggg tac ctg acc tcc ctt ggc ctg      672
 Ala Ala Gly Ile Arg Lys Gln Ala Gly Tyr Leu Thr Ser Leu Gly Leu
     210                 215                 220

 cca gtg gtg ggg gcc agc cat ggc tgg gcc agc gtt tct ggt aga gct      720
 Pro Val Val Gly Ala Ser His Gly Trp Ala Ser Val Ser Gly Arg Ala
 225                 230                 235                 240

 ctg gac gct gtc agc agc aga gcg gtc atc gtg cag cga tca ctg tca      768
 Leu Asp Ala Val Ser Ser Arg Ala Val Ile Val Gln Arg Ser Leu Ser
                 245                 250                 255

 gcc cgg gac ctg aac cat gcc aag gcg ggc tcc atc ctg gcc agc tac      816
 Ala Arg Asp Leu Asn His Ala Lys Ala Gly Ser Ile Leu Ala Ser Tyr
             260                 265                 270

 ctc aag atg ctc ccc atg ggc ctg atc atc atg ccg ggc atg atc agc      864
 Leu Lys Met Leu Pro Met Gly Leu Ile Ile Met Pro Gly Met Ile Ser
         275                 280                 285

 cgc gca ttg ttc cca ggg atg ccc ttg agg ctc aca ctg tgt gac atg      912
 Arg Ala Leu Phe Pro Gly Met Pro Leu Arg Leu Thr Leu Cys Asp Met
     290                 295                 300

 agg tac agc tcc tgg aac tgc cgg tca aac atc tcc acc acc tgg cca      960
 Arg Tyr Ser Ser Trp Asn Cys Arg Ser Asn Ile Ser Thr Thr Trp Pro
 305                 310                 315                 320

 gac agc aca gag atc aca ttc cgg tcc gtc cgc gcg gcc gac cac gtg     1008
 Asp Ser Thr Glu Ile Thr Phe Arg Ser Val Arg Ala Ala Asp His Val
                 325                 330                 335

 aag ctg caa cag agg gag ggg gcg ctg gtc agg cac atg acc ctg ctt     1056
 Lys Leu Gln Gln Arg Glu Gly Ala Leu Val Arg His Met Thr Leu Leu
             340                 345                 350

 cct ccg ccc agc ccc cgt gca ccc ata gcc gct ggg cct cag act gtg     1104
 Pro Pro Pro Ser Pro Arg Ala Pro Ile Ala Ala Gly Pro Gln Thr Val
         355                 360                 365

 gcc aca ggg ccc tgg gat caa gaa gtg aat ggg ggc aga gag cag gta     1152
 Ala Thr Gly Pro Trp Asp Gln Glu Val Asn Gly Gly Arg Glu Gln Val
     370                 375                 380

 gca gga cct gct gtg agg gag gag cag atg gta aag gct ggt gct ggg     1200
 Ala Gly Pro Ala Val Arg Glu Glu Gln Met Val Lys Ala Gly Ala Gly
 385                 390                 395                 400

 cac ggc aga ccc cag gaa gga cag ggc gag cct ggc tgg aac cca agt     1248
 His Gly Arg Pro Gln Glu Gly Gln Gly Glu Pro Gly Trp Asn Pro Ser
                 405                 410                 415

 gtc gag gat ggc caa ggg cat ccc gaa gta gaa tca cag gtg taa         1293
 Val Glu Asp Gly Gln Gly His Pro Glu Val Glu Ser Gln Val 
             420                 425                 430





      <210> 435
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 435
  atg gat tta tgg tac agt tgc aat ttg gtt gtc ctg cca gcc ctc ttg      48
  Met Asp Leu Trp Tyr Ser Cys Asn Leu Val Val Leu Pro Ala Leu Leu
    1               5                  10                  15

 gaa gaa ctt gcc cag atg aac agt gtg gac tcc aag gct cag att gag       96
 Glu Glu Leu Ala Gln Met Asn Ser Val Asp Ser Lys Ala Gln Ile Glu
              20                  25                  30

 ggg ctc gct cct gat gct tgc tat gcc aga ccc cag gtt ata act ata      144
 Gly Leu Ala Pro Asp Ala Cys Tyr Ala Arg Pro Gln Val Ile Thr Ile
          35                  40                  45

 aac cac act gcc att gag cag gcc cac agc cag gaa gtc atc gcc att      192
 Asn His Thr Ala Ile Glu Gln Ala His Ser Gln Glu Val Ile Ala Ile
      50                  55                  60

 caa ccc tgg aat gag aag aca cat ggg gaa tgc tca ctg aga gga aat      240
 Gln Pro Trp Asn Glu Lys Thr His Gly Glu Cys Ser Leu Arg Gly Asn
  65                  70                  75                  80

 tca gga gtt ccg aat gat gct ttg tct gtt gac tgg gct tct agt att      288
 Ser Gly Val Pro Asn Asp Ala Leu Ser Val Asp Trp Ala Ser Ser Ile
                  85                  90                  95

 act ttg atc agg gta aag gag aga aag atc tac agg gag gtg gtg gag      336
 Thr Leu Ile Arg Val Lys Glu Arg Lys Ile Tyr Arg Glu Val Val Glu
             100                 105                 110

 tct gag tct gaa gac agc ctg gtt cca gag cct gtg ctc tta aac act      384
 Ser Glu Ser Glu Asp Ser Leu Val Pro Glu Pro Val Leu Leu Asn Thr
         115                 120                 125

 gtc cat gca gca gag aag gag aaa caa gtc tga                          417
 Val His Ala Ala Glu Lys Glu Lys Gln Val 
     130                 135





      <210> 436
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 436
  atg gtg gca tgg ccc tgc cct atg att gca gag ctg cta tgg aca gct      48
  Met Val Ala Trp Pro Cys Pro Met Ile Ala Glu Leu Leu Trp Thr Ala
    1               5                  10                  15

 cct gag ctg ctg ccg ggg cct ggg cgc cct ggg cgg cgc acc ctc aca       96
 Pro Glu Leu Leu Pro Gly Pro Gly Arg Pro Gly Arg Arg Thr Leu Thr
              20                  25                  30

 ggg gac atc ttc agc act ggc atc atc ctg cag gag gtg ctg act cgg      144
 Gly Asp Ile Phe Ser Thr Gly Ile Ile Leu Gln Glu Val Leu Thr Arg
          35                  40                  45

 gcc cac tct act gct cct cgg gac ttc cag tgg aag cct tca gca act      192
 Ala His Ser Thr Ala Pro Arg Asp Phe Gln Trp Lys Pro Ser Ala Thr
      50                  55                  60

 ctg cca gaa tag                                                      204
 Leu Pro Glu 
  65





      <210> 437
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 437
  atg atg att cca ttg aat tgg aag tta aca ttg cca cct gga ctc ttc      48
  Met Met Ile Pro Leu Asn Trp Lys Leu Thr Leu Pro Pro Gly Leu Phe
    1               5                  10                  15

 ggg ctc ctc cta ccc tta agt caa cag gct aag aag gga gtt aca gta       96
 Gly Leu Leu Leu Pro Leu Ser Gln Gln Ala Lys Lys Gly Val Thr Val
              20                  25                  30

 ttg gct ggg gtg att ggc cca gac tct caa gat gaa atc agc cta cta      144
 Leu Ala Gly Val Ile Gly Pro Asp Ser Gln Asp Glu Ile Ser Leu Leu
          35                  40                  45

 ctc cac agt gga ggt aag gaa gag tat gca tgg aat aca gga ggc cca      192
 Leu His Ser Gly Gly Lys Glu Glu Tyr Ala Trp Asn Thr Gly Gly Pro
      50                  55                  60

 tta ggg ggt ctc tta gta tta cca tgc cct atg ttt aag gtc aat ggg      240
 Leu Gly Gly Leu Leu Val Leu Pro Cys Pro Met Phe Lys Val Asn Gly
  65                  70                  75                  80

 aaa tta caa cag ccc aat cca gac agg act aca aaa gac cca gac cct      288
 Lys Leu Gln Gln Pro Asn Pro Asp Arg Thr Thr Lys Asp Pro Asp Pro
                  85                  90                  95

 tca gga atg aag gtt tgg atc acc cta cca gga gaa aaa cca caa cct      336
 Ser Gly Met Lys Val Trp Ile Thr Leu Pro Gly Glu Lys Pro Gln Pro
             100                 105                 110

 gct gag gtg ctt gct gaa ggc aaa ggg aat aca gag tgg gta gta gaa      384
 Ala Glu Val Leu Ala Glu Gly Lys Gly Asn Thr Glu Trp Val Val Glu
         115                 120                 125

 gaa tgt agt cat caa tac cag cta caa cca cgt gac cag ctg cag aaa      432
 Glu Cys Ser His Gln Tyr Gln Leu Gln Pro Arg Asp Gln Leu Gln Lys
     130                 135                 140

 cga ggg ctg taa                                                      444
 Arg Gly Leu 
 145





      <210> 438
      <211> 570
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(570)

      <400> 438
  atg cca ttc ctg act ctc cca tgg tgc ctg gca gga ccc cct ggg ctg      48
  Met Pro Phe Leu Thr Leu Pro Trp Cys Leu Ala Gly Pro Pro Gly Leu
    1               5                  10                  15

 gtg agg aat ctc caa gtc aca gac aga tcg aac acc agc atc act ctg       96
 Val Arg Asn Leu Gln Val Thr Asp Arg Ser Asn Thr Ser Ile Thr Leu
              20                  25                  30

 agc tgg gct ggg cca gac acc cag gaa ggg gat gaa gcc cag ggg tat      144
 Ser Trp Ala Gly Pro Asp Thr Gln Glu Gly Asp Glu Ala Gln Gly Tyr
          35                  40                  45

 gtg gtg gag ctg tgc agc tca gac agt ctc cag tgg ctc ccg tgc cat      192
 Val Val Glu Leu Cys Ser Ser Asp Ser Leu Gln Trp Leu Pro Cys His
      50                  55                  60

 gtg ggc acc gtg cca gtc acc acc tac acg gcc aag ggg ctt cgg cct      240
 Val Gly Thr Val Pro Val Thr Thr Tyr Thr Ala Lys Gly Leu Arg Pro
  65                  70                  75                  80

 gga gag ggc tac ttc gtg cgg gtg aca gca gtt aat gaa gga ggc cag      288
 Gly Glu Gly Tyr Phe Val Arg Val Thr Ala Val Asn Glu Gly Gly Gln
                  85                  90                  95

 agc cag ccc agt gcc ctg gac aca tta gtg caa gcc atg cct gtt act      336
 Ser Gln Pro Ser Ala Leu Asp Thr Leu Val Gln Ala Met Pro Val Thr
             100                 105                 110

 gtc tgt ccc aag ttc ctc gtg gac tcc agc acc aag gac ttg ctg aca      384
 Val Cys Pro Lys Phe Leu Val Asp Ser Ser Thr Lys Asp Leu Leu Thr
         115                 120                 125

 gtc aag gtc ggg gac aca gtt cgt gtg ccc gtc tcc ttt gaa tca gtg      432
 Val Lys Val Gly Asp Thr Val Arg Val Pro Val Ser Phe Glu Ser Val
     130                 135                 140

 ctt gtg gaa atc act gac tgg gct tgt gga aat cag gtg aga gac atg      480
 Leu Val Glu Ile Thr Asp Trp Ala Cys Gly Asn Gln Val Arg Asp Met
 145                 150                 155                 160

 agg cag gaa gga ttc agg tcc tcc ttg aag gta ctg ccc tca ctt ggc      528
 Arg Gln Glu Gly Phe Arg Ser Ser Leu Lys Val Leu Pro Ser Leu Gly
                 165                 170                 175

 ggc tgg gtg gcc att ctg ctc cag gcc tgc aaa tcc ctc tag              570
 Gly Trp Val Ala Ile Leu Leu Gln Ala Cys Lys Ser Leu 
             180                 185





      <210> 439
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 439
  atg gga ctt atg caa aga act gca cac tgg gca aga gcc agc ccc ggt      48
  Met Gly Leu Met Gln Arg Thr Ala His Trp Ala Arg Ala Ser Pro Gly
    1               5                  10                  15

 ggc atc ctg gtc atg aag tcc tgc tcc ccg acg tgc ccc aac agc act       96
 Gly Ile Leu Val Met Lys Ser Cys Ser Pro Thr Cys Pro Asn Ser Thr
              20                  25                  30

 gtg tcc tcc gac agc cgc gcc ctc tct gtg tcc tgc tgc cag ggt agc      144
 Val Ser Ser Asp Ser Arg Ala Leu Ser Val Ser Cys Cys Gln Gly Ser
          35                  40                  45

 cag tgc aac cgc agt gca gcc gca ggc ctg gtg ggc agc ccc ggg acc      192
 Gln Cys Asn Arg Ser Ala Ala Ala Gly Leu Val Gly Ser Pro Gly Thr
      50                  55                  60

 ctg tgg gcc agc atc gca gcc agc cag ctg tgg gcc ctg ctg cag gca      240
 Leu Trp Ala Ser Ile Ala Ala Ser Gln Leu Trp Ala Leu Leu Gln Ala
  65                  70                  75                  80

 gcc cgc tga                                                          249
 Ala Arg 






      <210> 440
      <211> 492
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(492)

      <400> 440
  atg atg gtc gtc ctc ctg ggc gcg acg acc cta gtg ctc gtc gcc gtg      48
  Met Met Val Val Leu Leu Gly Ala Thr Thr Leu Val Leu Val Ala Val
    1               5                  10                  15

 gcg cca tgg gtg ttg tcc gca gcc gca ggt gag agg cgg gga gga gag       96
 Ala Pro Trp Val Leu Ser Ala Ala Ala Gly Glu Arg Arg Gly Gly Glu
              20                  25                  30

 tct tgg cgc agg gcg gga ggt agg gca cgc agc tgg gct acg ggg gcg      144
 Ser Trp Arg Arg Ala Gly Gly Arg Ala Arg Ser Trp Ala Thr Gly Ala
          35                  40                  45

 gcg atg ctg ttg ggg gcg aca gac gcc cag tct ggg aaa cct tcg gtc      192
 Ala Met Leu Leu Gly Ala Thr Asp Ala Gln Ser Gly Lys Pro Ser Val
      50                  55                  60

 cac ttt gcc gcg cca aag att aaa ccc gac ctg ggc tcg caa atc aac      240
 His Phe Ala Ala Pro Lys Ile Lys Pro Asp Leu Gly Ser Gln Ile Asn
  65                  70                  75                  80

 cag gag aaa gtg gtg ttc tgg gtc ctc tct tgc cgc ttg cct gtg gcc      288
 Gln Glu Lys Val Val Phe Trp Val Leu Ser Cys Arg Leu Pro Val Ala
                  85                  90                  95

 gtg tac ggg tcc tcg gga gcg ccc ggg tcc cac ccc cgt gaa atg gcg      336
 Val Tyr Gly Ser Ser Gly Ala Pro Gly Ser His Pro Arg Glu Met Ala
             100                 105                 110

 gtg cca gag ctt tgt gtc gag ttt gat tct ttc cgg gaa act cat cag      384
 Val Pro Glu Leu Cys Val Glu Phe Asp Ser Phe Arg Glu Thr His Gln
         115                 120                 125

 ata ttg tta gtg tat ttt gtg tgt ggc cca aga cag ttg ttc ttc cag      432
 Ile Leu Leu Val Tyr Phe Val Cys Gly Pro Arg Gln Leu Phe Phe Gln
     130                 135                 140

 tgt ggc cca cgg aag cca aaa aga gtg gac acc ctt gat gca gat gag      480
 Cys Gly Pro Arg Lys Pro Lys Arg Val Asp Thr Leu Asp Ala Asp Glu
 145                 150                 155                 160

 gcc tgc aga tag                                                      492
 Ala Cys Arg 






      <210> 441
      <211> 669
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(669)

      <400> 441
  atg ctg ctc tgc acg gct cgc ctg gtc ggc ctg cag ctt ctc att tcc      48
  Met Leu Leu Cys Thr Ala Arg Leu Val Gly Leu Gln Leu Leu Ile Ser
    1               5                  10                  15

 tgc tgc tgg gcc ttt gcc tgc cat agc acg gag tct tct cct gac ttc       96
 Cys Cys Trp Ala Phe Ala Cys His Ser Thr Glu Ser Ser Pro Asp Phe
              20                  25                  30

 acc ctc ccc gga gat tac ctc ctg gca ggc ctg ttc cct ctc cat tct      144
 Thr Leu Pro Gly Asp Tyr Leu Leu Ala Gly Leu Phe Pro Leu His Ser
          35                  40                  45

 ggc tgt ctg cag gtg agg cac aga ccc gag gtg acc ctg tgt gac agg      192
 Gly Cys Leu Gln Val Arg His Arg Pro Glu Val Thr Leu Cys Asp Arg
      50                  55                  60

 tct tgt agc ttc aat gag cat ggc tac cac ctc ttc cag gct atg cgg      240
 Ser Cys Ser Phe Asn Glu His Gly Tyr His Leu Phe Gln Ala Met Arg
  65                  70                  75                  80

 ctt ggg gtt gag gag ata aac aac tcc acg gcc ctg ctg ccc aac atc      288
 Leu Gly Val Glu Glu Ile Asn Asn Ser Thr Ala Leu Leu Pro Asn Ile
                  85                  90                  95

 acc ctg ggg tac cag ctg tat gat gtg tgt tct gac tct gcc aat gtg      336
 Thr Leu Gly Tyr Gln Leu Tyr Asp Val Cys Ser Asp Ser Ala Asn Val
             100                 105                 110

 tat gcc acg ctg aga gtg ctc tcc ctg cca ggg caa cac cac ata gag      384
 Tyr Ala Thr Leu Arg Val Leu Ser Leu Pro Gly Gln His His Ile Glu
         115                 120                 125

 ctc caa gga gac ctt ctc cac tat tcc cct acg gtg ctg gca gtg att      432
 Leu Gln Gly Asp Leu Leu His Tyr Ser Pro Thr Val Leu Ala Val Ile
     130                 135                 140

 ggg cct gac agc acc aac cgt gct gcc acc aca gcc gcc ctg ctg agc      480
 Gly Pro Asp Ser Thr Asn Arg Ala Ala Thr Thr Ala Ala Leu Leu Ser
 145                 150                 155                 160

 cct ttc ctg gtg ccc atg agc tgc ttc cag atc cct gcc tcc act ctc      528
 Pro Phe Leu Val Pro Met Ser Cys Phe Gln Ile Pro Ala Ser Thr Leu
                 165                 170                 175

 atg gga aaa ccc att ctc ctt ggg aac tac tgc cac tca gct gta ccc      576
 Met Gly Lys Pro Ile Leu Leu Gly Asn Tyr Cys His Ser Ala Val Pro
             180                 185                 190

 ctg ctg ccc tcc act tcc ctc ctc cct cca gag gtt ccg ttg cct ttg      624
 Leu Leu Pro Ser Thr Ser Leu Leu Pro Pro Glu Val Pro Leu Pro Leu
         195                 200                 205

 tta gga atg gac atc ctg gac ggg cgc tgt ggc tca tgc ctg taa          669
 Leu Gly Met Asp Ile Leu Asp Gly Arg Cys Gly Ser Cys Leu 
     210                 215                 220





      <210> 442
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 442
  atg act ctg cag ttc acc cag gcc tca ttg cac ctt ttc ttc cag gtg      48
  Met Thr Leu Gln Phe Thr Gln Ala Ser Leu His Leu Phe Phe Gln Val
    1               5                  10                  15

 gtt tac atc ttg gag aaa aaa cat tct cga gca gca acc ggc ttc ctc       96
 Val Tyr Ile Leu Glu Lys Lys His Ser Arg Ala Ala Thr Gly Phe Leu
              20                  25                  30

 aaa ctc ttg gct gat aag aac agc gaa ctg ttt agg aaa tac gcc ctg      144
 Lys Leu Leu Ala Asp Lys Asn Ser Glu Leu Phe Arg Lys Tyr Ala Leu
          35                  40                  45

 ttt tct ccc tca gac cac cga gtg cct aga att tat gtg cct ctc aag      192
 Phe Ser Pro Ser Asp His Arg Val Pro Arg Ile Tyr Val Pro Leu Lys
      50                  55                  60

 gac tgt ccc cag gac ttt gtg gca cgg cct aaa gat tat gcc aac aca      240
 Asp Cys Pro Gln Asp Phe Val Ala Arg Pro Lys Asp Tyr Ala Asn Thr
  65                  70                  75                  80

 ctg ttc atc tgc cgc att gtg gac tgg aag gag gac tgc aat ttt gcc      288
 Leu Phe Ile Cys Arg Ile Val Asp Trp Lys Glu Asp Cys Asn Phe Ala
                  85                  90                  95

 ctg ggg tag                                                          297
 Leu Gly 






      <210> 443
      <211> 306
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(306)

      <400> 443
  atg ggc ggc atc aga gca ctc ctg ccc agt ctt ggg gtt gct cct gga      48
  Met Gly Gly Ile Arg Ala Leu Leu Pro Ser Leu Gly Val Ala Pro Gly
    1               5                  10                  15

 tgc tgt ctg gga ggc ttg ctc atg gtg aca tcc tct tct ccc cgt cca       96
 Cys Cys Leu Gly Gly Leu Leu Met Val Thr Ser Ser Ser Pro Arg Pro
              20                  25                  30

 cgt tac cgc att cag agc ttg ggt cac ctg gac act gaa ctc agt tcc      144
 Arg Tyr Arg Ile Gln Ser Leu Gly His Leu Asp Thr Glu Leu Ser Ser
          35                  40                  45

 tat ggg aat act ctc ttt gaa gaa ccc atg aag cag tgt cag gct ggt      192
 Tyr Gly Asn Thr Leu Phe Glu Glu Pro Met Lys Gln Cys Gln Ala Gly
      50                  55                  60

 acg agg atc agc agt gat ttc ttt gag gag gag agc ctg ttt ctt cac      240
 Thr Arg Ile Ser Ser Asp Phe Phe Glu Glu Glu Ser Leu Phe Leu His
  65                  70                  75                  80

 tca cag gct atg tct gag tgg aac aag aag aac aga gtg ccc ttt tat      288
 Ser Gln Ala Met Ser Glu Trp Asn Lys Lys Asn Arg Val Pro Phe Tyr
                  85                  90                  95

 gag att ttg tct gcg tag                                              306
 Glu Ile Leu Ser Ala 
             100





      <210> 444
      <211> 1005
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1005)

      <400> 444
  atg ctg ttg ctt gtg ggt tta atc ttg gcc ata aag gta agg aat caa      48
  Met Leu Leu Leu Val Gly Leu Ile Leu Ala Ile Lys Val Arg Asn Gln
    1               5                  10                  15

 gac tca gct ggt gca att gat aaa cct ggg ctc tca gca acg tgg aaa       96
 Asp Ser Ala Gly Ala Ile Asp Lys Pro Gly Leu Ser Ala Thr Trp Lys
              20                  25                  30

 gaa aca ggc cag cat ctt tgg gga aag gat ctt cac ata ccg tgg cga      144
 Glu Thr Gly Gln His Leu Trp Gly Lys Asp Leu His Ile Pro Trp Arg
          35                  40                  45

 cca ggt aac tgt gca cag acc gag gtg att gag gca aaa aga tgc aat      192
 Pro Gly Asn Cys Ala Gln Thr Glu Val Ile Glu Ala Lys Arg Cys Asn
      50                  55                  60

 ggg tat tca gta att gat gga gaa act ctt gaa gaa att gag gca gga      240
 Gly Tyr Ser Val Ile Asp Gly Glu Thr Leu Glu Glu Ile Glu Ala Gly
  65                  70                  75                  80

 aaa ttg tct aag aat tgg act gcc caa act tgt gag ctg ttt gca ctc      288
 Lys Leu Ser Lys Asn Trp Thr Ala Gln Thr Cys Glu Leu Phe Ala Leu
                  85                  90                  95

 agc caa gcc tta aag tac ttg cag aac cag gaa gga gcc atc tat acc      336
 Ser Gln Ala Leu Lys Tyr Leu Gln Asn Gln Glu Gly Ala Ile Tyr Thr
             100                 105                 110

 aat tct aag tac gcc ttt gga gtg gct cat aca ttc gga aaa att tgg      384
 Asn Ser Lys Tyr Ala Phe Gly Val Ala His Thr Phe Gly Lys Ile Trp
         115                 120                 125

 act gaa cga gct tcc cct aag tct tct tcc aaa aac tct cac aat gaa      432
 Thr Glu Arg Ala Ser Pro Lys Ser Ser Ser Lys Asn Ser His Asn Glu
     130                 135                 140

 act gtt gtt cct cct cca tct aat gag aag acc aag gta gct att gta      480
 Thr Val Val Pro Pro Pro Ser Asn Glu Lys Thr Lys Val Ala Ile Val
 145                 150                 155                 160

 aaa gtt aaa gac cta aaa caa act ttg gca act gag aca gga tat caa      528
 Lys Val Lys Asp Leu Lys Gln Thr Leu Ala Thr Glu Thr Gly Tyr Gln
                 165                 170                 175

 gat gtg aat gcc tgg ttg gaa tgg atc aaa tac tcc att cgc act tta      576
 Asp Val Asn Ala Trp Leu Glu Trp Ile Lys Tyr Ser Ile Arg Thr Leu
             180                 185                 190

 aac aaa agc aat tgt tat gct tgt gca cac agc aga cca gag gcc cag      624
 Asn Lys Ser Asn Cys Tyr Ala Cys Ala His Ser Arg Pro Glu Ala Gln
         195                 200                 205

 att gtt ccc ttt cca cta gga tgg tcc ttc agt caa cga ggc atg ggc      672
 Ile Val Pro Phe Pro Leu Gly Trp Ser Phe Ser Gln Arg Gly Met Gly
     210                 215                 220

 tgt atg gta gct ctt ttc cag ggt tcc aca gcc tgg tgt aac aag tca      720
 Cys Met Val Ala Leu Phe Gln Gly Ser Thr Ala Trp Cys Asn Lys Ser
 225                 230                 235                 240

 tgt caa tct ctc tct ctg ctc tat ccc aaa gtt caa cac ctt gca ggt      768
 Cys Gln Ser Leu Ser Leu Leu Tyr Pro Lys Val Gln His Leu Ala Gly
                 245                 250                 255

 cag ccc cca agg acc atc cag ctt cct tct cct gac act aag ttc act      816
 Gln Pro Pro Arg Thr Ile Gln Leu Pro Ser Pro Asp Thr Lys Phe Thr
             260                 265                 270

 tca tgt ctc tca caa caa gga gga aac tta gct ttg ctt gga aac cta      864
 Ser Cys Leu Ser Gln Gln Gly Gly Asn Leu Ala Leu Leu Gly Asn Leu
         275                 280                 285

 aaa gat gca gta agc tta aga ctt tcc aag agc tta cca atc agt cag      912
 Lys Asp Ala Val Ser Leu Arg Leu Ser Lys Ser Leu Pro Ile Ser Gln
     290                 295                 300

 ccc tta tac aat cct gag cag att tat ggt ggt att gtg gtg gat ctt      960
 Pro Leu Tyr Asn Pro Glu Gln Ile Tyr Gly Gly Ile Val Val Asp Leu
 305                 310                 315                 320

 tac agg aca ctc tgt caa gta act gga gca gcg ctg gtg ctc tag         1005
 Tyr Arg Thr Leu Cys Gln Val Thr Gly Ala Ala Leu Val Leu 
                 325                 330





      <210> 445
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 445
  atg gcc tgg cag agg gcc ctg ctg cag ctg gca gga cca agt ttc cat      48
  Met Ala Trp Gln Arg Ala Leu Leu Gln Leu Ala Gly Pro Ser Phe His
    1               5                  10                  15

 gcg gtg ctg ctg gtg gct ggg agg agt gat ggc cgc aag ggt tcc ttg       96
 Ala Val Leu Leu Val Ala Gly Arg Ser Asp Gly Arg Lys Gly Ser Leu
              20                  25                  30

 gac aca gac gtg gct cat gtc tgg ctt cct ccc aac gcc ctc atc ctt      144
 Asp Thr Asp Val Ala His Val Trp Leu Pro Pro Asn Ala Leu Ile Leu
          35                  40                  45

 gag gga cct gac agc ttc cag atg ggt gcg gtc act gcc tcc ttc ccg      192
 Glu Gly Pro Asp Ser Phe Gln Met Gly Ala Val Thr Ala Ser Phe Pro
      50                  55                  60

 gag tcc agc agg cag gca gcc cgg ccc agc gga gga gct gcc caa ggc      240
 Glu Ser Ser Arg Gln Ala Ala Arg Pro Ser Gly Gly Ala Ala Gln Gly
  65                  70                  75                  80

 ctc tcc ctg ccc ctg ggg gaa gtc cct ctc acg tcc ttt cgc gtc ctt      288
 Leu Ser Leu Pro Leu Gly Glu Val Pro Leu Thr Ser Phe Arg Val Leu
                  85                  90                  95

 ctc tgc gtc gtc cgg gcc ctc tga                                      312
 Leu Cys Val Val Arg Ala Leu 
             100





      <210> 446
      <211> 363
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(363)

      <400> 446
  atg agc gtg tgc atg tca gtg agt gga cct ctg gct ctg gca tgt gcc      48
  Met Ser Val Cys Met Ser Val Ser Gly Pro Leu Ala Leu Ala Cys Ala
    1               5                  10                  15

 tgc cgg cca ctg agc ctg ggt ctg agt tcc gtg tgc aca tgt cca tat       96
 Cys Arg Pro Leu Ser Leu Gly Leu Ser Ser Val Cys Thr Cys Pro Tyr
              20                  25                  30

 gtg aac atg ccc cag aac att gac ctt gga aac cac aag ttg aaa atg      144
 Val Asn Met Pro Gln Asn Ile Asp Leu Gly Asn His Lys Leu Lys Met
          35                  40                  45

 gag gca cca cag atg gaa gga gtg tgg att cct aaa gca ccc ttg gca      192
 Glu Ala Pro Gln Met Glu Gly Val Trp Ile Pro Lys Ala Pro Leu Ala
      50                  55                  60

 gca gag cca cct gct gat cag gca tac cca gta caa gga aga gac caa      240
 Ala Glu Pro Pro Ala Asp Gln Ala Tyr Pro Val Gln Gly Arg Asp Gln
  65                  70                  75                  80

 gga ggc aag gag tat gag gag gca aga act ggc tgg ttt gca agc aga      288
 Gly Gly Lys Glu Tyr Glu Glu Ala Arg Thr Gly Trp Phe Ala Ser Arg
                  85                  90                  95

 agt gaa aag aat aca gag agc cca gaa atc tgc atc cca caa gag tca      336
 Ser Glu Lys Asn Thr Glu Ser Pro Glu Ile Cys Ile Pro Gln Glu Ser
             100                 105                 110

 gaa gag gcc act gct tcc aaa cag taa                                  363
 Glu Glu Ala Thr Ala Ser Lys Gln 
         115                 120





      <210> 447
      <211> 1203
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1203)

      <400> 447
  atg gac tcg gcc cct ctg ttc ccc agg ccc cac ctc ttc cag aac ctc      48
  Met Asp Ser Ala Pro Leu Phe Pro Arg Pro His Leu Phe Gln Asn Leu
    1               5                  10                  15

 ctg ctc ttc ctg tgg gcc ctg ctg aac tgt ggt ttg ggg gtc agt gct       96
 Leu Leu Phe Leu Trp Ala Leu Leu Asn Cys Gly Leu Gly Val Ser Ala
              20                  25                  30

 cag gac tgc ccc cca ggg gct gtg ccc ttc cga gac cta cag tgt gcc      144
 Gln Asp Cys Pro Pro Gly Ala Val Pro Phe Arg Asp Leu Gln Cys Ala
          35                  40                  45

 ctg tac aat ggc cgc cct gtc ctg ggc acc cag aag acc tac cag tgg      192
 Leu Tyr Asn Gly Arg Pro Val Leu Gly Thr Gln Lys Thr Tyr Gln Trp
      50                  55                  60

 gtg ccc ttc cat ggg gcg ccc aac cag tgc gac ctc aac tgc ctg gct      240
 Val Pro Phe His Gly Ala Pro Asn Gln Cys Asp Leu Asn Cys Leu Ala
  65                  70                  75                  80

 gag ggg cac gcc ttc tac cac agc ttc ggc cgc gtc ctg gac ggc acc      288
 Glu Gly His Ala Phe Tyr His Ser Phe Gly Arg Val Leu Asp Gly Thr
                  85                  90                  95

 gcc tgc agc ccg ggt gcc cag ggg gtc tgc gtg gct ggc cgc tgc ctt      336
 Ala Cys Ser Pro Gly Ala Gln Gly Val Cys Val Ala Gly Arg Cys Leu
             100                 105                 110

 agc gcc ggc tgt gat ggg ttg ttg ggc tcg ggt gcc ctc gag gac cgc      384
 Ser Ala Gly Cys Asp Gly Leu Leu Gly Ser Gly Ala Leu Glu Asp Arg
         115                 120                 125

 tgt ggc cgc tgc gga ggc gcc aac gac tcg tgc ctt ttc gtg cag cgc      432
 Cys Gly Arg Cys Gly Gly Ala Asn Asp Ser Cys Leu Phe Val Gln Arg
     130                 135                 140

 gtg ttt cgt gac gcc ggt gcc ttc gct ggg tac tgg aac gtg acc ctg      480
 Val Phe Arg Asp Ala Gly Ala Phe Ala Gly Tyr Trp Asn Val Thr Leu
 145                 150                 155                 160

 atc ccc gag ggc gcc aga cac atc cgc gtg gaa cac agg agc cgc aac      528
 Ile Pro Glu Gly Ala Arg His Ile Arg Val Glu His Arg Ser Arg Asn
                 165                 170                 175

 cac ctg ggt atc cta gga tca ctg atg ggg ggc gat ggg cgc tac gtg      576
 His Leu Gly Ile Leu Gly Ser Leu Met Gly Gly Asp Gly Arg Tyr Val
             180                 185                 190

 ctt aat ggg cac tgg gtg gtc agc cca cca ggg acc tac gag gcg gcc      624
 Leu Asn Gly His Trp Val Val Ser Pro Pro Gly Thr Tyr Glu Ala Ala
         195                 200                 205

 ggc acg cat gtg gtc tac acc cga gac aca ggg ccc cag gag aca ttg      672
 Gly Thr His Val Val Tyr Thr Arg Asp Thr Gly Pro Gln Glu Thr Leu
     210                 215                 220

 caa gca gcc ggg ccc acc tcc cat gac ctg ctc cta cag gtc ctc ctg      720
 Gln Ala Ala Gly Pro Thr Ser His Asp Leu Leu Leu Gln Val Leu Leu
 225                 230                 235                 240

 cag gag ccc aac cct ggc atc gag ttt gag ttc tgg ctc cct cgg gag      768
 Gln Glu Pro Asn Pro Gly Ile Glu Phe Glu Phe Trp Leu Pro Arg Glu
                 245                 250                 255

 cgc tac agc ccc ttc cag gct cgt gtg cag gcc ctg ggc tgg ccc ctg      816
 Arg Tyr Ser Pro Phe Gln Ala Arg Val Gln Ala Leu Gly Trp Pro Leu
             260                 265                 270

 agg cag cct cag ccc cgg ggg gtg gag cct cag ccc ccc gca gcc cct      864
 Arg Gln Pro Gln Pro Arg Gly Val Glu Pro Gln Pro Pro Ala Ala Pro
         275                 280                 285

 gct gtc acc cct gca cag acc cca acg ctg gcc cca gtg ttc cag gcc      912
 Ala Val Thr Pro Ala Gln Thr Pro Thr Leu Ala Pro Val Phe Gln Ala
     290                 295                 300

 cga gtg ctg ggc cac cac cac cag gcc cag gag acc cgc tat gag gtg      960
 Arg Val Leu Gly His His His Gln Ala Gln Glu Thr Arg Tyr Glu Val
 305                 310                 315                 320

 cgc atc cag ctc gtc tac aag aac cgc tcg cca ctg cgg gca cgc gag     1008
 Arg Ile Gln Leu Val Tyr Lys Asn Arg Ser Pro Leu Arg Ala Arg Glu
                 325                 330                 335

 tac gtg tgg gcg cca ggc cac tgc ccc tgc ccg atg ctg gca ccc cac     1056
 Tyr Val Trp Ala Pro Gly His Cys Pro Cys Pro Met Leu Ala Pro His
             340                 345                 350

 cgg gac tac ctg atg gct gtc cag cgt ctt gtc agc ccc gac ggc aca     1104
 Arg Asp Tyr Leu Met Ala Val Gln Arg Leu Val Ser Pro Asp Gly Thr
         355                 360                 365

 cag gac cag ctg ctg ctg ccc cac gcc ggc tac gcc cgg ccc tgg agc     1152
 Gln Asp Gln Leu Leu Leu Pro His Ala Gly Tyr Ala Arg Pro Trp Ser
     370                 375                 380

 cct gcg gag gac agc cgc ata cgc ctg act gcc cgg cgc tgt cct ggc     1200
 Pro Ala Glu Asp Ser Arg Ile Arg Leu Thr Ala Arg Arg Cys Pro Gly
 385                 390                 395                 400

 tga                                                                 1203
 






      <210> 448
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 448
  atg aag ctg agc tac tgc atc tgt gct ccg ttc ttt cgg tac caa ctg      48
  Met Lys Leu Ser Tyr Cys Ile Cys Ala Pro Phe Phe Arg Tyr Gln Leu
    1               5                  10                  15

 ttc ctt gct tcc tgc cta ggg gtc cag ctt atc atg ggc atg ctg tct       96
 Phe Leu Ala Ser Cys Leu Gly Val Gln Leu Ile Met Gly Met Leu Ser
              20                  25                  30

 gaa aaa cca agg tct ggg act cct gct gaa gtg gca gcc tgt gag cga      144
 Glu Lys Pro Arg Ser Gly Thr Pro Ala Glu Val Ala Ala Cys Glu Arg
          35                  40                  45

 gtc cag cag aaa gct gca gtg acc ctg gct cgt ctc agc cga gac cca      192
 Val Gln Gln Lys Ala Ala Val Thr Leu Ala Arg Leu Ser Arg Asp Pro
      50                  55                  60

 gat gtg gca cgg gag gcc gtg cgg ctc agc tgc atg tcc cgt ctc atc      240
 Asp Val Ala Arg Glu Ala Val Arg Leu Ser Cys Met Ser Arg Leu Ile
  65                  70                  75                  80

 gag ctc tgc aga tcc cca tca gag agg aac agc agt gac gcc gtg ctt      288
 Glu Leu Cys Arg Ser Pro Ser Glu Arg Asn Ser Ser Asp Ala Val Leu
                  85                  90                  95

 gtg gcc tgc ctg aag aaa gtg ctg gct ctt gtg ttc aaa gaa cat aag      336
 Val Ala Cys Leu Lys Lys Val Leu Ala Leu Val Phe Lys Glu His Lys
             100                 105                 110

 ggg gaa gtg atg gat tta aag atc ctt caa gct gtc tca cag taa          381
 Gly Glu Val Met Asp Leu Lys Ile Leu Gln Ala Val Ser Gln 
         115                 120                 125





      <210> 449
      <211> 714
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(714)

      <400> 449
  atg ggc ccg gtc cct ctg gta tgg gcc atg agc cag ctg agc ctg agt      48
  Met Gly Pro Val Pro Leu Val Trp Ala Met Ser Gln Leu Ser Leu Ser
    1               5                  10                  15

 gca aaa atg gac aga agg cga act gga gtc atg atg aca tca acc cct       96
 Ala Lys Met Asp Arg Arg Arg Thr Gly Val Met Met Thr Ser Thr Pro
              20                  25                  30

 ata acc tgg ggg aca ctc gag aaa acc atg cag gaa gct gag aaa cta      144
 Ile Thr Trp Gly Thr Leu Glu Lys Thr Met Gln Glu Ala Glu Lys Leu
          35                  40                  45

 ctg gag cgt caa ggc cag aaa aaa ccc ctg att cca tgt tct tgg cca      192
 Leu Glu Arg Gln Gly Gln Lys Lys Pro Leu Ile Pro Cys Ser Trp Pro
      50                  55                  60

 tgg agg aaa ggt cca att caa gaa aca ata tgg aaa gca gca ctg ctg      240
 Trp Arg Lys Gly Pro Ile Gln Glu Thr Ile Trp Lys Ala Ala Leu Leu
  65                  70                  75                  80

 ttc aca aac ggt agt atc cgg gta gga aca ctc tct aat acc agt act      288
 Phe Thr Asn Gly Ser Ile Arg Val Gly Thr Leu Ser Asn Thr Ser Thr
                  85                  90                  95

 gct act caa cac agt ctt aat gtt aca ttt gta aag aat atc acc act      336
 Ala Thr Gln His Ser Leu Asn Val Thr Phe Val Lys Asn Ile Thr Thr
             100                 105                 110

 caa ttt atg gtt tgt ggt ttt aat cct tat gtc ttt ttg gca gct aag      384
 Gln Phe Met Val Cys Gly Phe Asn Pro Tyr Val Phe Leu Ala Ala Lys
         115                 120                 125

 gcg gac cag ctc cag gtg gta gtc agc cac acc aca act gcc agc cag      432
 Ala Asp Gln Leu Gln Val Val Val Ser His Thr Thr Thr Ala Ser Gln
     130                 135                 140

 gaa agg gta agg gcg cag ggc tgc ctg ctg ccc cct cag tgc cag tgt      480
 Glu Arg Val Arg Ala Gln Gly Cys Leu Leu Pro Pro Gln Cys Gln Cys
 145                 150                 155                 160

 cct ctg ccc aga aag gtc aaa tcg gca gag cag ggt gcg gaa agc acc      528
 Pro Leu Pro Arg Lys Val Lys Ser Ala Glu Gln Gly Ala Glu Ser Thr
                 165                 170                 175

 ctg agg aaa gca gga tcc cta gtt tcc agg ctt ccc tgc cag aga gag      576
 Leu Arg Lys Ala Gly Ser Leu Val Ser Arg Leu Pro Cys Gln Arg Glu
             180                 185                 190

 act gga aag acc ata gaa gga aag ttt ctc ctt tca cag ggg gaa gga      624
 Thr Gly Lys Thr Ile Glu Gly Lys Phe Leu Leu Ser Gln Gly Glu Gly
         195                 200                 205

 tac agg gag aca gcg cag aag ttg gag agc agc atc gaa atg ttt ctg      672
 Tyr Arg Glu Thr Ala Gln Lys Leu Glu Ser Ser Ile Glu Met Phe Leu
     210                 215                 220

 gcc tat gtg gct tgc acc atc cga ttc ccg gca gtg tta taa              714
 Ala Tyr Val Ala Cys Thr Ile Arg Phe Pro Ala Val Leu 
 225                 230                 235





      <210> 450
      <211> 636
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(636)

      <400> 450
  atg cta acc ttt aaa gtc tta ttg ttt ttg gag agt ttc cac ccc tcc      48
  Met Leu Thr Phe Lys Val Leu Leu Phe Leu Glu Ser Phe His Pro Ser
    1               5                  10                  15

 agg ttc gaa gcc att acc aga gtg ctg ctg aag ccc ctt gca gat gtg       96
 Arg Phe Glu Ala Ile Thr Arg Val Leu Leu Lys Pro Leu Ala Asp Val
              20                  25                  30

 agg gga cct ctc atg cca agt ctt atg gct gca aag aca tcg cat tcc      144
 Arg Gly Pro Leu Met Pro Ser Leu Met Ala Ala Lys Thr Ser His Ser
          35                  40                  45

 aca gtg tgg tgt cag aga aga gaa act tct gat ttt aac ttt gct tct      192
 Thr Val Trp Cys Gln Arg Arg Glu Thr Ser Asp Phe Asn Phe Ala Ser
      50                  55                  60

 ttg ctg gga aga gaa ttc tac aaa caa cga tca aca gtc ttg gtc cca      240
 Leu Leu Gly Arg Glu Phe Tyr Lys Gln Arg Ser Thr Val Leu Val Pro
  65                  70                  75                  80

 ctg gca act gtc atg gga gca ggt gcc agt gtg act aca gca ttc ttc      288
 Leu Ala Thr Val Met Gly Ala Gly Ala Ser Val Thr Thr Ala Phe Phe
                  85                  90                  95

 cca atg aac aat gaa gtg tta tca gac ctg aag ggt ggg cag gat tca      336
 Pro Met Asn Asn Glu Val Leu Ser Asp Leu Lys Gly Gly Gln Asp Ser
             100                 105                 110

 ggg ctg aaa gaa gca aac aga aaa ata gga act cag tgt tcc ctt cct      384
 Gly Leu Lys Glu Ala Asn Arg Lys Ile Gly Thr Gln Cys Ser Leu Pro
         115                 120                 125

 gtt gca aaa tac ctt aat tcc cca agt agc tgt gaa ctg aca gat ttt      432
 Val Ala Lys Tyr Leu Asn Ser Pro Ser Ser Cys Glu Leu Thr Asp Phe
     130                 135                 140

 cat tta att att caa agc aaa att tca agg aat aat gtg aga caa cag      480
 His Leu Ile Ile Gln Ser Lys Ile Ser Arg Asn Asn Val Arg Gln Gln
 145                 150                 155                 160

 ctt tca aga agg gct cag cag agg tac tca gag tgg aga gtt gga ctg      528
 Leu Ser Arg Arg Ala Gln Gln Arg Tyr Ser Glu Trp Arg Val Gly Leu
                 165                 170                 175

 aaa gag ggt tct cag gag ctg gca tca cta agt gga agt ggg agt gag      576
 Lys Glu Gly Ser Gln Glu Leu Ala Ser Leu Ser Gly Ser Gly Ser Glu
             180                 185                 190

 gat gat ggg aca gca gtt cac cag cag cca aag gcc tgg act ggg gcc      624
 Asp Asp Gly Thr Ala Val His Gln Gln Pro Lys Ala Trp Thr Gly Ala
         195                 200                 205

 ctg gtg gag tag                                                      636
 Leu Val Glu 
     210





      <210> 451
      <211> 375
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(375)

      <400> 451
  atg ttg ttc cct ccg cgc tgg acg gga gca gct gga gcg gga gcc tgg      48
  Met Leu Phe Pro Pro Arg Trp Thr Gly Ala Ala Gly Ala Gly Ala Trp
    1               5                  10                  15

 ctg cgc tac cgc ggc tgc ctc ctg ctg tgc agg tcc ccg acc ctc tct       96
 Leu Arg Tyr Arg Gly Cys Leu Leu Leu Cys Arg Ser Pro Thr Leu Ser
              20                  25                  30

 ctg tcc tca ttg cgc cca gac ggg ccg gcc cag agc tcc cgg gtc gtc      144
 Leu Ser Ser Leu Arg Pro Asp Gly Pro Ala Gln Ser Ser Arg Val Val
          35                  40                  45

 ttt cgt gtg gcc gcg agg agg aaa gac ggt ccc cac acc ctt ggg gag      192
 Phe Arg Val Ala Ala Arg Arg Lys Asp Gly Pro His Thr Leu Gly Glu
      50                  55                  60

 agg gac tca cag aaa cac aca caa aca ctg gag aaa ggg aga tac aaa      240
 Arg Asp Ser Gln Lys His Thr Gln Thr Leu Glu Lys Gly Arg Tyr Lys
  65                  70                  75                  80

 agc ccg gac acc cgt gca cat aca cac gga gaa ata cac ccg gtc acc      288
 Ser Pro Asp Thr Arg Ala His Thr His Gly Glu Ile His Pro Val Thr
                  85                  90                  95

 tgg gaa cac acg tac acg cca gcc ttt ccc cca acc act ccg gga cac      336
 Trp Glu His Thr Tyr Thr Pro Ala Phe Pro Pro Thr Thr Pro Gly His
             100                 105                 110

 aca tcc aca gac ccc aaa cca aat cct aca ccc gaa tga                  375
 Thr Ser Thr Asp Pro Lys Pro Asn Pro Thr Pro Glu 
         115                 120





      <210> 452
      <211> 870
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(870)

      <400> 452
  atg ctg ttt gca gca att cta ctg tca cga tgg gat gtc aca tcg tcg      48
  Met Leu Phe Ala Ala Ile Leu Leu Ser Arg Trp Asp Val Thr Ser Ser
    1               5                  10                  15

 ttg gta ctc cag ctt ggg agg cac ctg aca tcc atc tgt gaa agt gca       96
 Leu Val Leu Gln Leu Gly Arg His Leu Thr Ser Ile Cys Glu Ser Ala
              20                  25                  30

 ggc agc ttg gag agc agg ccc tgc agc tcc tgc tct ggg gac aag ctc      144
 Gly Ser Leu Glu Ser Arg Pro Cys Ser Ser Cys Ser Gly Asp Lys Leu
          35                  40                  45

 tgc atc cca agc tct gaa cct gaa gca gga cac cca ggg cct agt cct      192
 Cys Ile Pro Ser Ser Glu Pro Glu Ala Gly His Pro Gly Pro Ser Pro
      50                  55                  60

 ggt gct ccc tac aag ggg gta ggg gaa tca gct cct ctc cct agg ttt      240
 Gly Ala Pro Tyr Lys Gly Val Gly Glu Ser Ala Pro Leu Pro Arg Phe
  65                  70                  75                  80

 ctg ttt cct tgg cta cca aac aga cga gga atg act gct gat gaa agc      288
 Leu Phe Pro Trp Leu Pro Asn Arg Arg Gly Met Thr Ala Asp Glu Ser
                  85                  90                  95

 gtc tgc gta gcg gcc act cag act gtg tca aat att cct ccg gcg tcc      336
 Val Cys Val Ala Ala Thr Gln Thr Val Ser Asn Ile Pro Pro Ala Ser
             100                 105                 110

 cgc ccc ggg ctc tct ctg caa agg ccc aac ctc ctc aca gat gct ccg      384
 Arg Pro Gly Leu Ser Leu Gln Arg Pro Asn Leu Leu Thr Asp Ala Pro
         115                 120                 125

 ctg cct cgt tca gcc agc atc tgg agt aac tgc caa gta gac agc aac      432
 Leu Pro Arg Ser Ala Ser Ile Trp Ser Asn Cys Gln Val Asp Ser Asn
     130                 135                 140

 tgc tgc tct gct gcc ccc aag agg acc gtg gcc aac aca gac att gtg      480
 Cys Cys Ser Ala Ala Pro Lys Arg Thr Val Ala Asn Thr Asp Ile Val
 145                 150                 155                 160

 cgg ttg tct tgg gta tgt ctt tat cag gag tgt gaa aat gga cca aat      528
 Arg Leu Ser Trp Val Cys Leu Tyr Gln Glu Cys Glu Asn Gly Pro Asn
                 165                 170                 175

 aca gta aat tgg tac cag aag tgg ggt gtt gct gaa aat ata ccc gaa      576
 Thr Val Asn Trp Tyr Gln Lys Trp Gly Val Ala Glu Asn Ile Pro Glu
             180                 185                 190

 aat gtg aaa gca act ttg gaa ctg ggt aac ggg cca aca ttg gaa cag      624
 Asn Val Lys Ala Thr Leu Glu Leu Gly Asn Gly Pro Thr Leu Glu Gln
         195                 200                 205

 ttt gga ggg ctc aga aga aga cag gaa aat gtg agg gtc ttc tct tac      672
 Phe Gly Gly Leu Arg Arg Arg Gln Glu Asn Val Arg Val Phe Ser Tyr
     210                 215                 220

 caa aac cag tct ata aag ttt gga aaa aga atg cac gca tca aat gct      720
 Gln Asn Gln Ser Ile Lys Phe Gly Lys Arg Met His Ala Ser Asn Ala
 225                 230                 235                 240

 aca ttt gta agg ctt tgt aag gct aca aga att atg aag aat cag agg      768
 Thr Phe Val Arg Leu Cys Lys Ala Thr Arg Ile Met Lys Asn Gln Arg
                 245                 250                 255

 aat atg aaa cca aag gaa cac aat aaa ctt cta ata agt gac ctt aaa      816
 Asn Met Lys Pro Lys Glu His Asn Lys Leu Leu Ile Ser Asp Leu Lys
             260                 265                 270

 gaa ttg gac att gtc tat ggc cat acc act ctg aat atg ccc aat cct      864
 Glu Leu Asp Ile Val Tyr Gly His Thr Thr Leu Asn Met Pro Asn Pro
         275                 280                 285

 gtc tga                                                              870
 Val 






      <210> 453
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 453
  atg ggg ctc ctg atc tgg gga tac ctt tac ctg tgg gtg gaa acc ctc      48
  Met Gly Leu Leu Ile Trp Gly Tyr Leu Tyr Leu Trp Val Glu Thr Leu
    1               5                  10                  15

 acc aca tgt ggt gga aac cct acg gcc ctg gag ccc aag gag agc aac       96
 Thr Thr Cys Gly Gly Asn Pro Thr Ala Leu Glu Pro Lys Glu Ser Asn
              20                  25                  30

 ggc tgt aac aag tgc aca ggt ttg agt gcg ctg aga cag ggg aac cgt      144
 Gly Cys Asn Lys Cys Thr Gly Leu Ser Ala Leu Arg Gln Gly Asn Arg
          35                  40                  45

 ggg caa aga ggt ccc tcc aaa aag agc tgg atg tgg ccc att ccc agc      192
 Gly Gln Arg Gly Pro Ser Lys Lys Ser Trp Met Trp Pro Ile Pro Ser
      50                  55                  60

 ccc tcg tgt ttc ttg gaa atg aga aag tcc agg aaa ggg cac agg ggc      240
 Pro Ser Cys Phe Leu Glu Met Arg Lys Ser Arg Lys Gly His Arg Gly
  65                  70                  75                  80

 ttt cgc aac gac cgt ggc gat gat agc ttt gac gtg tgg tca tcc agc      288
 Phe Arg Asn Asp Arg Gly Asp Asp Ser Phe Asp Val Trp Ser Ser Ser
                  85                  90                  95

 cgg cca ctg ccc aca ccc aag aga aag ctg gat tga                      324
 Arg Pro Leu Pro Thr Pro Lys Arg Lys Leu Asp 
             100                 105





      <210> 454
      <211> 426
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(426)

      <400> 454
  atg cat agc ggg gcc tgg cac aac tcc atc agt cac tat gta gcc gtg      48
  Met His Ser Gly Ala Trp His Asn Ser Ile Ser His Tyr Val Ala Val
    1               5                  10                  15

 ctc ctc ctg tgc ctg ttt cct cat ttg gaa acc gaa cac aac agt gcg       96
 Leu Leu Leu Cys Leu Phe Pro His Leu Glu Thr Glu His Asn Ser Ala
              20                  25                  30

 tcc gtc gat agt att tca gga cat gtc cta cag caa gat gct aca gac      144
 Ser Val Asp Ser Ile Ser Gly His Val Leu Gln Gln Asp Ala Thr Asp
          35                  40                  45

 cag aat ctt gca aag tgt gaa gtt cat cag cca aga atg cta aca gcc      192
 Gln Asn Leu Ala Lys Cys Glu Val His Gln Pro Arg Met Leu Thr Ala
      50                  55                  60

 tca gta ccc cac cct tca ctg gtg gcc tgt gac cct cag aaa aat ggc      240
 Ser Val Pro His Pro Ser Leu Val Ala Cys Asp Pro Gln Lys Asn Gly
  65                  70                  75                  80

 aag gac ttc ctg gtc agc cct tgg ggc ctg cag gga ggc ggc ggc aag      288
 Lys Asp Phe Leu Val Ser Pro Trp Gly Leu Gln Gly Gly Gly Gly Lys
                  85                  90                  95

 gca agg cag ctg cag ctg tca ggg tct agg ggg cga cgg tgg gct cgg      336
 Ala Arg Gln Leu Gln Leu Ser Gly Ser Arg Gly Arg Arg Trp Ala Arg
             100                 105                 110

 cgc cct ccc agt gag gtg gtg gcg gca tgc gag tct cct cgg cgc ggc      384
 Arg Pro Pro Ser Glu Val Val Ala Ala Cys Glu Ser Pro Arg Arg Gly
         115                 120                 125

 ggc agc agt ttt cag att gag gcc aag aga cct gtg acg tga              426
 Gly Ser Ser Phe Gln Ile Glu Ala Lys Arg Pro Val Thr 
     130                 135                 140





      <210> 455
      <211> 843
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(843)

      <400> 455
  atg aga gat ggg cct atc ctc cca gcc tac atc ttt ctc ctg tcc tgg      48
  Met Arg Asp Gly Pro Ile Leu Pro Ala Tyr Ile Phe Leu Leu Ser Trp
    1               5                  10                  15

 atg ctt cct gct ctt gaa cat cgg act cca agt tct tca gtt ttg aga       96
 Met Leu Pro Ala Leu Glu His Arg Thr Pro Ser Ser Ser Val Leu Arg
              20                  25                  30

 ctt gga cta gct ctc ctt gct cct cag ctt gca gac agc cta ttg tgg      144
 Leu Gly Leu Ala Leu Leu Ala Pro Gln Leu Ala Asp Ser Leu Leu Trp
          35                  40                  45

 gac ctt gtg ata gta cct ata acc aaa cta aag tcc cag cag gcc cct      192
 Asp Leu Val Ile Val Pro Ile Thr Lys Leu Lys Ser Gln Gln Ala Pro
      50                  55                  60

 gga ggt gag gtt gag agt gtg acc tat gag gag gtg caa tac act caa      240
 Gly Gly Glu Val Glu Ser Val Thr Tyr Glu Glu Val Gln Tyr Thr Gln
  65                  70                  75                  80

 aaa gaa ctg ttt gag ttc cct aat tta tat aaa cag caa tct gga gaa      288
 Lys Glu Leu Phe Glu Phe Pro Asn Leu Tyr Lys Gln Gln Ser Gly Glu
                  85                  90                  95

 cag gca tgg gaa tgg ata tta agg gta tgg gat aat ggt gga agg aac      336
 Gln Ala Trp Glu Trp Ile Leu Arg Val Trp Asp Asn Gly Gly Arg Asn
             100                 105                 110

 ata gag ttg gat cag ttt gaa ttt att gat ctg gac aac caa agt tgc      384
 Ile Glu Leu Asp Gln Phe Glu Phe Ile Asp Leu Asp Asn Gln Ser Cys
         115                 120                 125

 cat ggt ggc agg gat ggc ggt tat gca tgg gct cag gaa cat gga ctt      432
 His Gly Gly Arg Asp Gly Gly Tyr Ala Trp Ala Gln Glu His Gly Leu
     130                 135                 140

 cca ctc acc aag gct gac ctg gct atg gcc act gct gag tgc cca att      480
 Pro Leu Thr Lys Ala Asp Leu Ala Met Ala Thr Ala Glu Cys Pro Ile
 145                 150                 155                 160

 ttc cag cag cag aga cca aca ctg agc act caa tat ggt acc att cct      528
 Phe Gln Gln Gln Arg Pro Thr Leu Ser Thr Gln Tyr Gly Thr Ile Pro
                 165                 170                 175

 cgg ggc gat cag cca gcc acc tgg tgg caa gtt aat tat att gga cct      576
 Arg Gly Asp Gln Pro Ala Thr Trp Trp Gln Val Asn Tyr Ile Gly Pro
             180                 185                 190

 ctt cca tca tgg aaa tgg cgg agg ttt gtc ctc act gga ata gac act      624
 Leu Pro Ser Trp Lys Trp Arg Arg Phe Val Leu Thr Gly Ile Asp Thr
         195                 200                 205

 tac tcc gga tat agt ttg cct atc ctg cac gca atg ctt ctg cca aga      672
 Tyr Ser Gly Tyr Ser Leu Pro Ile Leu His Ala Met Leu Leu Pro Arg
     210                 215                 220

 cta cca tcg atg gat tca cgg aat gcc tca tcc acc atc ata gta ttc      720
 Leu Pro Ser Met Asp Ser Arg Asn Ala Ser Ser Thr Ile Ile Val Phe
 225                 230                 235                 240

 cac aca gca ttg cct ctc acc aag gca ctc act tta cag cta aag aag      768
 His Thr Ala Leu Pro Leu Thr Lys Ala Leu Thr Leu Gln Leu Lys Lys
                 245                 250                 255

 tgt ggc agt ggg ctc atg ctc atg gaa ttc act ggt ctt aac atg ttc      816
 Cys Gly Ser Gly Leu Met Leu Met Glu Phe Thr Gly Leu Asn Met Phe
             260                 265                 270

 ccc atc gtc ctg aag cag ctg gat tga                                  843
 Pro Ile Val Leu Lys Gln Leu Asp 
         275                 280





      <210> 456
      <211> 351
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(351)

      <400> 456
  atg gac act ctg gtg cta gta tca gtc att ttg atc aca aga cgt gga      48
  Met Asp Thr Leu Val Leu Val Ser Val Ile Leu Ile Thr Arg Arg Gly
    1               5                  10                  15

 cca gcc cac ctt gga gct cac tgt ggt ggt ggc ctg gtc cta atg caa       96
 Pro Ala His Leu Gly Ala His Cys Gly Gly Gly Leu Val Leu Met Gln
              20                  25                  30

 gtc cta atg gag ctc ttg gaa ctg gct gta gcc ttt gct gag cag gag      144
 Val Leu Met Glu Leu Leu Glu Leu Ala Val Ala Phe Ala Glu Gln Glu
          35                  40                  45

 caa cta tgt ctc tgg ttc tta agg att gaa aag cca cct cct gcc tct      192
 Gln Leu Cys Leu Trp Phe Leu Arg Ile Glu Lys Pro Pro Pro Ala Ser
      50                  55                  60

 aaa gtg ctt gaa gac aca gta gga agg cac cag agg gca ttc tca gac      240
 Lys Val Leu Glu Asp Thr Val Gly Arg His Gln Arg Ala Phe Ser Asp
  65                  70                  75                  80

 cat cta ttt tca agg aaa tac agc tgg gaa gta caa aac aat tct cca      288
 His Leu Phe Ser Arg Lys Tyr Ser Trp Glu Val Gln Asn Asn Ser Pro
                  85                  90                  95

 ctt cgg cca gtt ttg gat gaa atg gtg gtt tct aac aca cac tca gaa      336
 Leu Arg Pro Val Leu Asp Glu Met Val Val Ser Asn Thr His Ser Glu
             100                 105                 110

 aca ctt gga gtc tga                                                  351
 Thr Leu Gly Val 
         115





      <210> 457
      <211> 936
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(936)

      <400> 457
  atg gac tta gcc cat tta tgc cta gtg ttc cat tat cag aac act aag      48
  Met Asp Leu Ala His Leu Cys Leu Val Phe His Tyr Gln Asn Thr Lys
    1               5                  10                  15

 cac gtg gga gtt att tat atc cta ctg ctc aag gtc atc gtc atc gcc       96
 His Val Gly Val Ile Tyr Ile Leu Leu Leu Lys Val Ile Val Ile Ala
              20                  25                  30

 aag ctc ttg gaa gcc ggg acg gct gct gtg gcc atc ctg act gtg ctt      144
 Lys Leu Leu Glu Ala Gly Thr Ala Ala Val Ala Ile Leu Thr Val Leu
          35                  40                  45

 cac aac ttg tca ctg acg gcg ctt tcc tta gag gag ggt gga gga gat      192
 His Asn Leu Ser Leu Thr Ala Leu Ser Leu Glu Glu Gly Gly Gly Asp
      50                  55                  60

 cat caa cag gga aag cac cgt ccg ccc gtt ctt ctg aat ctc agg tgc      240
 His Gln Gln Gly Lys His Arg Pro Pro Val Leu Leu Asn Leu Arg Cys
  65                  70                  75                  80

 agc cgt gtc tgt gtt gat cca ctg cgg acc cac caa ggg ctg tgt gac      288
 Ser Arg Val Cys Val Asp Pro Leu Arg Thr His Gln Gly Leu Cys Asp
                  85                  90                  95

 ttc ctg gtg gcc gca gag gct ctg cgc aaa cgc cgc agg tgg ctc tgc      336
 Phe Leu Val Ala Ala Glu Ala Leu Arg Lys Arg Arg Arg Trp Leu Cys
             100                 105                 110

 gtg tgg gct cac agg gcc cgc ccc gct cac gta cac gct ccc gca ggg      384
 Val Trp Ala His Arg Ala Arg Pro Ala His Val His Ala Pro Ala Gly
         115                 120                 125

 ccc gcc gcg ctc acg tac acg ctc ccg cag ggc ccg cca ccc ctg cgt      432
 Pro Ala Ala Leu Thr Tyr Thr Leu Pro Gln Gly Pro Pro Pro Leu Arg
     130                 135                 140

 aca cgc tcc cgc agg gcc cac cac ccc cgc gta cac gct ccc gca ggg      480
 Thr Arg Ser Arg Arg Ala His His Pro Arg Val His Ala Pro Ala Gly
 145                 150                 155                 160

 ccc gcc acg ctc acg tac acg ctc ccg cag ggc ccg ccg cgc tca cgt      528
 Pro Ala Thr Leu Thr Tyr Thr Leu Pro Gln Gly Pro Pro Arg Ser Arg
                 165                 170                 175

 cac gtg cac gga cgc cac ggt gcc cct cgc tgt ccc gag tca cct gca      576
 His Val His Gly Arg His Gly Ala Pro Arg Cys Pro Glu Ser Pro Ala
             180                 185                 190

 cgg acg cca cgg tgc ccc tcg ctg tcc cga gtc acc tgc acg gac gcc      624
 Arg Thr Pro Arg Cys Pro Ser Leu Ser Arg Val Thr Cys Thr Asp Ala
         195                 200                 205

 acg gtg ccc ctc gct gtc ccg agt cac ctg cac gac gcc acg gtg ccc      672
 Thr Val Pro Leu Ala Val Pro Ser His Leu His Asp Ala Thr Val Pro
     210                 215                 220

 ctc gct gtc ctg ggt cac ctg cac gac gcc aca gtg ccc ctc gct gtc      720
 Leu Ala Val Leu Gly His Leu His Asp Ala Thr Val Pro Leu Ala Val
 225                 230                 235                 240

 cta atc cac ctg cac gct tct cca gtt tct tct cta cac aga gat tat      768
 Leu Ile His Leu His Ala Ser Pro Val Ser Ser Leu His Arg Asp Tyr
                 245                 250                 255

 gat ggc acc ttt ccc att cat gtt gcc tgc ctt tcc ctg gag ccg act      816
 Asp Gly Thr Phe Pro Ile His Val Ala Cys Leu Ser Leu Glu Pro Thr
             260                 265                 270

 gcc ttg gcc acc cgt ggc ttt gtg atg ggc gtg ttc tgt gag gag gac      864
 Ala Leu Ala Thr Arg Gly Phe Val Met Gly Val Phe Cys Glu Glu Asp
         275                 280                 285

 gtc aac ttc ctg ccc gtc ttg acc ccc tct tct gtg aaa gga gac ctg      912
 Val Asn Phe Leu Pro Val Leu Thr Pro Ser Ser Val Lys Gly Asp Leu
     290                 295                 300

 ttg cag gcc ggc gga agc ggg tga                                      936
 Leu Gln Ala Gly Gly Ser Gly 
 305                 310





      <210> 458
      <211> 216
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(216)

      <400> 458
  atg gcg cca gcg ctg tgg cgg gcc tgc aac gga ctc atg gcc gcc ttc      48
  Met Ala Pro Ala Leu Trp Arg Ala Cys Asn Gly Leu Met Ala Ala Phe
    1               5                  10                  15

 ttc gcg ctg gcg gcc ttg gtg cag gtg gtg tac aca atc cct gca gta       96
 Phe Ala Leu Ala Ala Leu Val Gln Val Val Tyr Thr Ile Pro Ala Val
              20                  25                  30

 ctg acc ctg ctt gtt gga ctt aac cct gaa gtc aca gcc atg aag agt      144
 Leu Thr Leu Leu Val Gly Leu Asn Pro Glu Val Thr Ala Met Lys Ser
          35                  40                  45

 gac ttt tat ctg cgc tac tac gtg ggg cac aag ggc aag ttc agc cac      192
 Asp Phe Tyr Leu Arg Tyr Tyr Val Gly His Lys Gly Lys Phe Ser His
      50                  55                  60

 gag ttt ctg gag ttt gag ttc tga                                      216
 Glu Phe Leu Glu Phe Glu Phe 
  65                  70





      <210> 459
      <211> 315
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(315)

      <400> 459
  atg ttc ctc gtg ctg atg aga aca gtg tgt att cta tgg cag ttg gat      48
  Met Phe Leu Val Leu Met Arg Thr Val Cys Ile Leu Trp Gln Leu Asp
    1               5                  10                  15

 gaa gta ttc tat agc agt agt aga att agt gaa agt att aaa gct gtt       96
 Glu Val Phe Tyr Ser Ser Ser Arg Ile Ser Glu Ser Ile Lys Ala Val
              20                  25                  30

 gat ctc tcc gaa aaa tgc gta gaa gaa ata atg atg tgg acc ttc aat      144
 Asp Leu Ser Glu Lys Cys Val Glu Glu Ile Met Met Trp Thr Phe Asn
          35                  40                  45

 cct gct gtt ctc act aaa gcg aac att gtc cga agt gga gat gct gct      192
 Pro Ala Val Leu Thr Lys Ala Asn Ile Val Arg Ser Gly Asp Ala Ala
      50                  55                  60

 cag ggt gca gaa gga ggc acc tcg cag ttt caa gtg ggt gat ctt gta      240
 Gln Gly Ala Glu Gly Gly Thr Ser Gln Phe Gln Val Gly Asp Leu Val
  65                  70                  75                  80

 caa gtt tgt tat gac ctg gaa cga att aaa ctt cta caa aga gga cat      288
 Gln Val Cys Tyr Asp Leu Glu Arg Ile Lys Leu Leu Gln Arg Gly His
                  85                  90                  95

 gga gaa tgg gct gaa gcg atg ctt cca                                  315
 Gly Glu Trp Ala Glu Ala Met Leu Pro 
             100                 105





      <210> 460
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 460
  atg ttg gcg atg ttg gct ttg aag act gga gtg atg tgg cca caa gcc      48
  Met Leu Ala Met Leu Ala Leu Lys Thr Gly Val Met Trp Pro Gln Ala
    1               5                  10                  15

 aag gaa cat cag tgg cca cca gaa gct gga aga gaa gac aag gaa aat       96
 Lys Glu His Gln Trp Pro Pro Glu Ala Gly Arg Glu Asp Lys Glu Asn
              20                  25                  30

 gcg ctc cta cca gag cag cca tct tgc tat tat tcc atc cag ttt cca      144
 Ala Leu Leu Pro Glu Gln Pro Ser Cys Tyr Tyr Ser Ile Gln Phe Pro
          35                  40                  45

 gat ggg aaa gga ata tta agt cgt tgg aga tta atc cta cca aag caa      192
 Asp Gly Lys Gly Ile Leu Ser Arg Trp Arg Leu Ile Leu Pro Lys Gln
      50                  55                  60

 atc gga aat ttc caa agc tgt tgt caa tat ggc tct gca gtt taa          237
 Ile Gly Asn Phe Gln Ser Cys Cys Gln Tyr Gly Ser Ala Val 
  65                  70                  75





      <210> 461
      <211> 633
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(633)

      <400> 461
  atg ctg gcc tct gtg gag gaa cgg tcc ttg tct att cct ggg atc tgg      48
  Met Leu Ala Ser Val Glu Glu Arg Ser Leu Ser Ile Pro Gly Ile Trp
    1               5                  10                  15

 ggc tca ggg aag tcc gag gcc ctg tgg ctg tgg ccc agg aaa atg ctg       96
 Gly Ser Gly Lys Ser Glu Ala Leu Trp Leu Trp Pro Arg Lys Met Leu
              20                  25                  30

 gag gcc tgg tgg ggg gtg ctg tgt gtc cac tgt ccg acc tgc ctt ggt      144
 Glu Ala Trp Trp Gly Val Leu Cys Val His Cys Pro Thr Cys Leu Gly
          35                  40                  45

 gcc ctg gct tct cct ccc atg ctg cgt ctg gct gtg cca ctt ccc caa      192
 Ala Leu Ala Ser Pro Pro Met Leu Arg Leu Ala Val Pro Leu Pro Gln
      50                  55                  60

 gcc agc aaa gtc tgg tct gag agc ata aag gat acg gag gct gga ctt      240
 Ala Ser Lys Val Trp Ser Glu Ser Ile Lys Asp Thr Glu Ala Gly Leu
  65                  70                  75                  80

 ccc ctg gcc agc ctg tgg acc act ggg ggg ctg ctt ccc atg cag ttt      288
 Pro Leu Ala Ser Leu Trp Thr Thr Gly Gly Leu Leu Pro Met Gln Phe
                  85                  90                  95

 gag tca gca aat att gac cag ggg ctg ctc tgt gcc agg cct cgg ggg      336
 Glu Ser Ala Asn Ile Asp Gln Gly Leu Leu Cys Ala Arg Pro Arg Gly
             100                 105                 110

 agg gct cca ggc ccc gag gtg cat ggg caa cac tgg atg ggg ttc tgg      384
 Arg Ala Pro Gly Pro Glu Val His Gly Gln His Trp Met Gly Phe Trp
         115                 120                 125

 gtg ccc cac agg gca gaa gcc gag aag gac aga gct ctg gcc atg cct      432
 Val Pro His Arg Ala Glu Ala Glu Lys Asp Arg Ala Leu Ala Met Pro
     130                 135                 140

 aca ggc atc ttc ctg gcc ctg cca ccc cct agg gat gtt gtc cag gag      480
 Thr Gly Ile Phe Leu Ala Leu Pro Pro Pro Arg Asp Val Val Gln Glu
 145                 150                 155                 160

 cac tgg ctc ctt ggc ggg ccc atc tta cca gaa ctg ggt gtg ttc tgt      528
 His Trp Leu Leu Gly Gly Pro Ile Leu Pro Glu Leu Gly Val Phe Cys
                 165                 170                 175

 aag cca gtg cag tcc ggg gaa ggc ctt ggc ggt ttg ctg act gtg act      576
 Lys Pro Val Gln Ser Gly Glu Gly Leu Gly Gly Leu Leu Thr Val Thr
             180                 185                 190

 tct gct gct ggg gga cag tcc ggg gcc agc agc act tgc tct gtg ctg      624
 Ser Ala Ala Gly Gly Gln Ser Gly Ala Ser Ser Thr Cys Ser Val Leu
         195                 200                 205

 ggg ctg tga                                                          633
 Gly Leu 
     210





      <210> 462
      <211> 642
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(642)

      <400> 462
  atg ttg ctt ttc cct att cct gat gtt gtc atg gtt gta tgg ctg tgt      48
  Met Leu Leu Phe Pro Ile Pro Asp Val Val Met Val Val Trp Leu Cys
    1               5                  10                  15

 ttt ata caa atg act tgt gaa acc aac cct gcc tta aca gcc ggc atc       96
 Phe Ile Gln Met Thr Cys Glu Thr Asn Pro Ala Leu Thr Ala Gly Ile
              20                  25                  30

 gta acc ttc atg ttt tct ttt cca ggg tat att tcc ttc cag cta cgt      144
 Val Thr Phe Met Phe Ser Phe Pro Gly Tyr Ile Ser Phe Gln Leu Arg
          35                  40                  45

 tca ctt gaa aaa tgc ctg tgt aaa gaa caa agg cgt aat gaa ggc gat      192
 Ser Leu Glu Lys Cys Leu Cys Lys Glu Gln Arg Arg Asn Glu Gly Asp
      50                  55                  60

 ctc ttc cac cgg ctg tgg cac atc atg aat gaa atc ctg gac ctg agg      240
 Leu Phe His Arg Leu Trp His Ile Met Asn Glu Ile Leu Asp Leu Arg
  65                  70                  75                  80

 cgg cag gtg ctg gtg ggc cac ctc acc cac gac cgg atg aag gac gtg      288
 Arg Gln Val Leu Val Gly His Leu Thr His Asp Arg Met Lys Asp Val
                  85                  90                  95

 aag cgc cac att act gcc cgg ctt gac tgg ggc aat gaa caa ctg gga      336
 Lys Arg His Ile Thr Ala Arg Leu Asp Trp Gly Asn Glu Gln Leu Gly
             100                 105                 110

 ctg gac ctg gtg cct agg aaa gag tac gca atg gtg gat ccg gaa gac      384
 Leu Asp Leu Val Pro Arg Lys Glu Tyr Ala Met Val Asp Pro Glu Asp
         115                 120                 125

 atc agc att act gag ctc tac cga ttg gta gaa agc aga gcc tta ata      432
 Ile Ser Ile Thr Glu Leu Tyr Arg Leu Val Glu Ser Arg Ala Leu Ile
     130                 135                 140

 cag aat aaa tgg aat gcg tat cag atg gag gac ctt aaa gca gag ctt      480
 Gln Asn Lys Trp Asn Ala Tyr Gln Met Glu Asp Leu Lys Ala Glu Leu
 145                 150                 155                 160

 gaa aat gga aca cag gac ctg gtt acc gca aaa agc caa cta tca gtt      528
 Glu Asn Gly Thr Gln Asp Leu Val Thr Ala Lys Ser Gln Leu Ser Val
                 165                 170                 175

 cac agg aaa aga gaa gaa act aag tta atg gaa ccc aaa tac cca ccc      576
 His Arg Lys Arg Glu Glu Thr Lys Leu Met Glu Pro Lys Tyr Pro Pro
             180                 185                 190

 aga aga gag gaa gtg ata gag gag tac tgg tac cca gcc tca agc cac      624
 Arg Arg Glu Glu Val Ile Glu Glu Tyr Trp Tyr Pro Ala Ser Ser His
         195                 200                 205

 caa att aag gat ttt taa                                              642
 Gln Ile Lys Asp Phe 
     210





      <210> 463
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 463
  atg tct gtc tta tcc ttt ccc atc act gtc ttc agt tat gct tgg tcc      48
  Met Ser Val Leu Ser Phe Pro Ile Thr Val Phe Ser Tyr Ala Trp Ser
    1               5                  10                  15

 agt ctc ccc ttc atg acc ttt gag aaa atc tca ggc aga tct caa aac       96
 Ser Leu Pro Phe Met Thr Phe Glu Lys Ile Ser Gly Arg Ser Gln Asn
              20                  25                  30

 ttc aaa gtt cag ttt gaa agt tta gtg agg tat gat ctg agt gaa tgc      144
 Phe Lys Val Gln Phe Glu Ser Leu Val Arg Tyr Asp Leu Ser Glu Cys
          35                  40                  45

 ctg ctc tgt ggg ctg ctt gat gac aca gat aac atc cat tac aat aac      192
 Leu Leu Cys Gly Leu Leu Asp Asp Thr Asp Asn Ile His Tyr Asn Asn
      50                  55                  60

 aaa cta cac aag ctg aag ctc aaa acc tgt gaa tac gca aag gaa aca      240
 Lys Leu His Lys Leu Lys Leu Lys Thr Cys Glu Tyr Ala Lys Glu Thr
  65                  70                  75                  80

 aat tac atc tct ttg ggg gaa tcc tca gtg aat cag gcc aag gga tta      288
 Asn Tyr Ile Ser Leu Gly Glu Ser Ser Val Asn Gln Ala Lys Gly Leu
                  85                  90                  95

 gag gct aaa tgc aga ctg aga ggg gga gtc aag tag                      324
 Glu Ala Lys Cys Arg Leu Arg Gly Gly Val Lys 
             100                 105





      <210> 464
      <211> 486
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(486)

      <400> 464
  atg ggc gga gtg gcc cag gtg cgc tgg ctg ctt tgg cag ctc agg ctg      48
  Met Gly Gly Val Ala Gln Val Arg Trp Leu Leu Trp Gln Leu Arg Leu
    1               5                  10                  15

 ccg ctc cgg gcc gct gct ccc cgg ccg cct tca gat aac caa ctt ctc       96
 Pro Leu Arg Ala Ala Ala Pro Arg Pro Pro Ser Asp Asn Gln Leu Leu
              20                  25                  30

 aaa ctt ccc ttt ccg ggg ata tgt cct gat tgg ata ata aac tat gtg      144
 Lys Leu Pro Phe Pro Gly Ile Cys Pro Asp Trp Ile Ile Asn Tyr Val
          35                  40                  45

 atc aac cta ctt ccc act ctc aaa gat atg att ctg tac agc cct ctg      192
 Ile Asn Leu Leu Pro Thr Leu Lys Asp Met Ile Leu Tyr Ser Pro Leu
      50                  55                  60

 gtc agt aga tct tct agc aat tca ttt aat gaa ttc ctt tac ctg aga      240
 Val Ser Arg Ser Ser Ser Asn Ser Phe Asn Glu Phe Leu Tyr Leu Arg
  65                  70                  75                  80

 gga aga ttg cag agg caa ggg ttt gtg cca ggg tct cca ggg aat aaa      288
 Gly Arg Leu Gln Arg Gln Gly Phe Val Pro Gly Ser Pro Gly Asn Lys
                  85                  90                  95

 gac ttg ttc tac act cta gaa caa att gat cag gtg gtt gat ctt cgc      336
 Asp Leu Phe Tyr Thr Leu Glu Gln Ile Asp Gln Val Val Asp Leu Arg
             100                 105                 110

 cac ctg acc agt gaa gga ttt cag gaa atg cca ctc caa aat atg ctg      384
 His Leu Thr Ser Glu Gly Phe Gln Glu Met Pro Leu Gln Asn Met Leu
         115                 120                 125

 ctt tgg tat act gat tat ttt cag ttg aag gca ctt aaa gac cag caa      432
 Leu Trp Tyr Thr Asp Tyr Phe Gln Leu Lys Ala Leu Lys Asp Gln Gln
     130                 135                 140

 atg cag gga gga gga gag aca tgt gga aca gat gtg gac caa cct cct      480
 Met Gln Gly Gly Gly Glu Thr Cys Gly Thr Asp Val Asp Gln Pro Pro
 145                 150                 155                 160

 gat tga                                                              486
 Asp 






      <210> 465
      <211> 1275
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1275)

      <400> 465
  atg cac ctt gtg agt ttt gga agt cct gat gag caa ttt gaa att gct      48
  Met His Leu Val Ser Phe Gly Ser Pro Asp Glu Gln Phe Glu Ile Ala
    1               5                  10                  15

 gtt att ctt agc cat aga tac agt caa ttt ttg ttg ctc aca gta gtt       96
 Val Ile Leu Ser His Arg Tyr Ser Gln Phe Leu Leu Leu Thr Val Val
              20                  25                  30

 ata ttc tac aaa gtt gga cat gtg aca ggg gtg tgg ctc gcc tgt aat      144
 Ile Phe Tyr Lys Val Gly His Val Thr Gly Val Trp Leu Ala Cys Asn
          35                  40                  45

 cgg tca cca ctg ctg ctg ctg ctg ctg ctc aaa ccc ctg gca gga ggg      192
 Arg Ser Pro Leu Leu Leu Leu Leu Leu Leu Lys Pro Leu Ala Gly Gly
      50                  55                  60

 gga gca cag aga cag gca gat gca gga gcc agg gga aaa tat gta tgg      240
 Gly Ala Gln Arg Gln Ala Asp Ala Gly Ala Arg Gly Lys Tyr Val Trp
  65                  70                  75                  80

 aaa gaa ata aag gtg atg aac aag ggg agt gtg agc ttg gct atc cat      288
 Lys Glu Ile Lys Val Met Asn Lys Gly Ser Val Ser Leu Ala Ile His
                  85                  90                  95

 tcc tgt gct ttt gtg att gaa caa gag gag aaa aag aaa aca gaa gct      336
 Ser Cys Ala Phe Val Ile Glu Gln Glu Glu Lys Lys Lys Thr Glu Ala
             100                 105                 110

 cat aaa gaa gga gat gga gtg aag agg gct gat aag att ctg ggg gtt      384
 His Lys Glu Gly Asp Gly Val Lys Arg Ala Asp Lys Ile Leu Gly Val
         115                 120                 125

 acc aaa gat cct gga acc att gct ggt ctc aat gta gtt aga att atc      432
 Thr Lys Asp Pro Gly Thr Ile Ala Gly Leu Asn Val Val Arg Ile Ile
     130                 135                 140

 aat gag cca act gct gct tct att gct tat ggc aca gac aaa aag ttt      480
 Asn Glu Pro Thr Ala Ala Ser Ile Ala Tyr Gly Thr Asp Lys Lys Phe
 145                 150                 155                 160

 gga gct gaa aga cat gtg ctc atc tat gac tta aga gat gaa att ttt      528
 Gly Ala Glu Arg His Val Leu Ile Tyr Asp Leu Arg Asp Glu Ile Phe
                 165                 170                 175

 gat gtg tct gtc ctt act ctt gag gat gaa atc ttt gag atc aaa tct      576
 Asp Val Ser Val Leu Thr Leu Glu Asp Glu Ile Phe Glu Ile Lys Ser
             180                 185                 190

 aca gct gga gac acc cac tta ggt gaa gaa gat ttt gac aac caa atg      624
 Thr Ala Gly Asp Thr His Leu Gly Glu Glu Asp Phe Asp Asn Gln Met
         195                 200                 205

 atc aac cat ttt att gct gag ttc aaa tac aag cat aag gac agt aga      672
 Ile Asn His Phe Ile Ala Glu Phe Lys Tyr Lys His Lys Asp Ser Arg
     210                 215                 220

 gca gat att tat acc tcc att acc cat gcc caa ttt gaa gaa ctg aat      720
 Ala Asp Ile Tyr Thr Ser Ile Thr His Ala Gln Phe Glu Glu Leu Asn
 225                 230                 235                 240

 gct gtc ctg ttc cgt ggc acc cag gac ccc ata gag ata gcc ctt cag      768
 Ala Val Leu Phe Arg Gly Thr Gln Asp Pro Ile Glu Ile Ala Leu Gln
                 245                 250                 255

 gac acc aaa cta gac aag ttg cag atc cat gtt att gtc ctg acc cag      816
 Asp Thr Lys Leu Asp Lys Leu Gln Ile His Val Ile Val Leu Thr Gln
             260                 265                 270

 acc ttc act acc tac cct gac aac caa cct gat gtc ctc att caa gtt      864
 Thr Phe Thr Thr Tyr Pro Asp Asn Gln Pro Asp Val Leu Ile Gln Val
         275                 280                 285

 tat gaa ggt gag agt gcc ata acc aag gat aac aat ttg ctt gtt atc      912
 Tyr Glu Gly Glu Ser Ala Ile Thr Lys Asp Asn Asn Leu Leu Val Ile
     290                 295                 300

 cag ggc aag ttt gag ctc aca ggc ata ctt cct gct ccc ttt gct gtt      960
 Gln Gly Lys Phe Glu Leu Thr Gly Ile Leu Pro Ala Pro Phe Ala Val
 305                 310                 315                 320

 cct caa att aaa gtc act tgt gat att gat gtc aat agc agc ctc aat     1008
 Pro Gln Ile Lys Val Thr Cys Asp Ile Asp Val Asn Ser Ser Leu Asn
                 325                 330                 335

 atc tct gct gta ggt aag agt aca gaa aaa gag aac aaa att atc atc     1056
 Ile Ser Ala Val Gly Lys Ser Thr Glu Lys Glu Asn Lys Ile Ile Ile
             340                 345                 350

 act aat gac cag ggg cat ttg agc aag gaa gac att gag aat atg gtc     1104
 Thr Asn Asp Gln Gly His Leu Ser Lys Glu Asp Ile Glu Asn Met Val
         355                 360                 365

 cag gaa gct gag tac aaa gct gaa gat gag aag cag aag aac aag gtg     1152
 Gln Glu Ala Glu Tyr Lys Ala Glu Asp Glu Lys Gln Lys Asn Lys Val
     370                 375                 380

 gca tca aag aat tca ctt gac tct tat gca ttc aac atg aaa gca act     1200
 Ala Ser Lys Asn Ser Leu Asp Ser Tyr Ala Phe Asn Met Lys Ala Thr
 385                 390                 395                 400

 gag aaa ctt caa ggc aag atc aac aat aag gat aaa cag aag ata ctt     1248
 Glu Lys Leu Gln Gly Lys Ile Asn Asn Lys Asp Lys Gln Lys Ile Leu
                 405                 410                 415

 gac aag tgt aat aaa atc atc aac tga                                 1275
 Asp Lys Cys Asn Lys Ile Ile Asn 
             420





      <210> 466
      <211> 255
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(255)

      <400> 466
  atg aag atg atg ata atg atg ggg att gtg gtg ctg atg gga gtg gcc      48
  Met Lys Met Met Ile Met Met Gly Ile Val Val Leu Met Gly Val Ala
    1               5                  10                  15

 tgc agt gcc atc ctc atg tac ata ttc tgc act gat tgc tgg ctc atc       96
 Cys Ser Ala Ile Leu Met Tyr Ile Phe Cys Thr Asp Cys Trp Leu Ile
              20                  25                  30

 gct gtg ctc tac ttc act tgg ctg gtg ttt gac tgg aac aca ccc aag      144
 Ala Val Leu Tyr Phe Thr Trp Leu Val Phe Asp Trp Asn Thr Pro Lys
          35                  40                  45

 aaa gaa att cag aat gtg tgc aat gag aag ggc aaa gga cct ctg tat      192
 Lys Glu Ile Gln Asn Val Cys Asn Glu Lys Gly Lys Gly Pro Leu Tyr
      50                  55                  60

 att agc caa gta gta ctc aac cca cca ggg aca atg atg atg agg ata      240
 Ile Ser Gln Val Val Leu Asn Pro Pro Gly Thr Met Met Met Arg Ile
  65                  70                  75                  80

 gtt gcc att tat tga                                                  255
 Val Ala Ile Tyr 






      <210> 467
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 467
  atg aag tcc ggg gca gaa ccc aag ccc gtg cct tcc tcg ccc tgc ctt      48
  Met Lys Ser Gly Ala Glu Pro Lys Pro Val Pro Ser Ser Pro Cys Leu
    1               5                  10                  15

 cgg agt ttc ctg cta ttg acc tgg cgg ggc gcg cca gcc ctc cct gcc       96
 Arg Ser Phe Leu Leu Leu Thr Trp Arg Gly Ala Pro Ala Leu Pro Ala
              20                  25                  30

 cgc tgg tgc cgc ggt ccc tct cgg ctg cag cag tgg ggc aca ggg acg      144
 Arg Trp Cys Arg Gly Pro Ser Arg Leu Gln Gln Trp Gly Thr Gly Thr
          35                  40                  45

 tca tgg aca aaa gac gag gat gcc agt tcg atg tgc gag cag aag gcc      192
 Ser Trp Thr Lys Asp Glu Asp Ala Ser Ser Met Cys Glu Gln Lys Ala
      50                  55                  60

 gcc tgc gtg cgc tct gca gag caa ccg gcc cgg ttt cat aag ggg ccg      240
 Ala Cys Val Arg Ser Ala Glu Gln Pro Ala Arg Phe His Lys Gly Pro
  65                  70                  75                  80

 ccg gca ggg gac tgc cat ggc gcc ccc tcc tac cct ttt tgg cac cag      288
 Pro Ala Gly Asp Cys His Gly Ala Pro Ser Tyr Pro Phe Trp His Gln
                  85                  90                  95

 cag ctt cat ccg cag gcc cac tcg ggg tga                              318
 Gln Leu His Pro Gln Ala His Ser Gly 
             100                 105





      <210> 468
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 468
  atg gcc att cac tgg ctc gca tta tat ttt ggg acc att gta att gtt      48
  Met Ala Ile His Trp Leu Ala Leu Tyr Phe Gly Thr Ile Val Ile Val
    1               5                  10                  15

 cca aac ggg agc caa atg agc aaa act ttg cga aat aat tct gag tcc       96
 Pro Asn Gly Ser Gln Met Ser Lys Thr Leu Arg Asn Asn Ser Glu Ser
              20                  25                  30

 ctt gct gga aag cct cac ctg aat gca gcc cac aca ttt atg ata cac      144
 Leu Ala Gly Lys Pro His Leu Asn Ala Ala His Thr Phe Met Ile His
          35                  40                  45

 tac aaa ggc ttc aag gga aaa gcc aat gct gac ctg cag ctg ggg ctg      192
 Tyr Lys Gly Phe Lys Gly Lys Ala Asn Ala Asp Leu Gln Leu Gly Leu
      50                  55                  60

 aag tga                                                              198
 Lys 
  65





      <210> 469
      <211> 516
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(516)

      <400> 469
  atg ggg cta aga cct acg tgc att act cac tgt att ttt gtg ctt att      48
  Met Gly Leu Arg Pro Thr Cys Ile Thr His Cys Ile Phe Val Leu Ile
    1               5                  10                  15

 ctc tgc tct gtg gtg aaa gat att gtt gaa aat gtc aag aag gct atg       96
 Leu Cys Ser Val Val Lys Asp Ile Val Glu Asn Val Lys Lys Ala Met
              20                  25                  30

 aat aac agt gat agg aaa aag gga aag cat tta tgt ttc tct ata gca      144
 Asn Asn Ser Asp Arg Lys Lys Gly Lys His Leu Cys Phe Ser Ile Ala
          35                  40                  45

 ctg aaa gtc agg ctg ttg gag aaa ctg aat agc agt gta agt atg gaa      192
 Leu Lys Val Arg Leu Leu Glu Lys Leu Asn Ser Ser Val Ser Met Glu
      50                  55                  60

 cat gtc aca gaa gac tac ggt gtt aca atg acc acc ata tat gac ctg      240
 His Val Thr Glu Asp Tyr Gly Val Thr Met Thr Thr Ile Tyr Asp Leu
  65                  70                  75                  80

 aag aac aag gat aaa ctg ttg aag ttc cat gct gaa aat tta tac agt      288
 Lys Asn Lys Asp Lys Leu Leu Lys Phe His Ala Glu Asn Leu Tyr Ser
                  85                  90                  95

 gag aaa gca tct gct gac cat gaa gga gca gag caa ttc act gat gaa      336
 Glu Lys Ala Ser Ala Asp His Glu Gly Ala Glu Gln Phe Thr Asp Glu
             100                 105                 110

 ttt gcc aag gtc atc gct gat gga aat ctg atg cca gaa caa gtc tat      384
 Phe Ala Lys Val Ile Ala Asp Gly Asn Leu Met Pro Glu Gln Val Tyr
         115                 120                 125

 aat gct gtt aaa aca tca ctg ttt tgg tgt atg gtc cca gaa cga cac      432
 Asn Ala Val Lys Thr Ser Leu Phe Trp Cys Met Val Pro Glu Arg His
     130                 135                 140

 tgg cca cag ctg atg aga cag ctc cta cag gaa tta agg atg cca aag      480
 Trp Pro Gln Leu Met Arg Gln Leu Leu Gln Glu Leu Arg Met Pro Lys
 145                 150                 155                 160

 aca gaa cag ctg tgt tgg gat gtt cta atg cag tag                      516
 Thr Glu Gln Leu Cys Trp Asp Val Leu Met Gln 
                 165                 170





      <210> 470
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 470
  atg gct gca ctg agc cgg gca ctg ggt cca ctc aga acc cca gct cct      48
  Met Ala Ala Leu Ser Arg Ala Leu Gly Pro Leu Arg Thr Pro Ala Pro
    1               5                  10                  15

 cct ctg tgg att ggg ctc ttc cta gta gcc aca gga agt caa caa agc       96
 Pro Leu Trp Ile Gly Leu Phe Leu Val Ala Thr Gly Ser Gln Gln Ser
              20                  25                  30

 ctg gcc cag ccc ttg cca gga aac acc aca gag gcc aca cca cga agt      144
 Leu Ala Gln Pro Leu Pro Gly Asn Thr Thr Glu Ala Thr Pro Arg Ser
          35                  40                  45

 ctg agg gcc tcc ggg tcc ttg tgt gga ccc cat gct aaa gca cca tac      192
 Leu Arg Ala Ser Gly Ser Leu Cys Gly Pro His Ala Lys Ala Pro Tyr
      50                  55                  60

 ctg tgc gag gcc acc cat gaa cct gct gca gcc agg att cgt gcc caa      240
 Leu Cys Glu Ala Thr His Glu Pro Ala Ala Ala Arg Ile Arg Ala Gln
  65                  70                  75                  80

 gtc ccc gac acg cgc tgg agc agg gtt ggg ggt cag cgg ttc tac agc      288
 Val Pro Asp Thr Arg Trp Ser Arg Val Gly Gly Gln Arg Phe Tyr Ser
                  85                  90                  95

 cgt gtc ctg agc ccc ctg cac cgt gga ccc tca ggg cac act gag gcc      336
 Arg Val Leu Ser Pro Leu His Arg Gly Pro Ser Gly His Thr Glu Ala
             100                 105                 110

 tct gct cag agg tcc cac atg ggg aag ctg aag gag ccg cag cct cag      384
 Ser Ala Gln Arg Ser His Met Gly Lys Leu Lys Glu Pro Gln Pro Gln
         115                 120                 125

 gac cac aag cca ggg tta ggt gct tcc taa                              414
 Asp His Lys Pro Gly Leu Gly Ala Ser 
     130                 135





      <210> 471
      <211> 552
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(552)

      <400> 471
  atg agc cta gga ttg ggg gca ctg gct gcc aca cag gca gcc ctt acc      48
  Met Ser Leu Gly Leu Gly Ala Leu Ala Ala Thr Gln Ala Ala Leu Thr
    1               5                  10                  15

 acg cta cgg tta tgt cct tgc aag ttt gat tct tac ccg tac cag tgg       96
 Thr Leu Arg Leu Cys Pro Cys Lys Phe Asp Ser Tyr Pro Tyr Gln Trp
              20                  25                  30

 gcc ccg gaa ggt ctg ccc atg cct cac ctg ccc aag gtt ctg tgc agg      144
 Ala Pro Glu Gly Leu Pro Met Pro His Leu Pro Lys Val Leu Cys Arg
          35                  40                  45

 aat ggg aat ggc gtg gaa ggc agc agg gag gag agc ctt cta aca gtc      192
 Asn Gly Asn Gly Val Glu Gly Ser Arg Glu Glu Ser Leu Leu Thr Val
      50                  55                  60

 cta cga ggt agg caa gga aac ggc ggt gct ggg aca atc tat gtc act      240
 Leu Arg Gly Arg Gln Gly Asn Gly Gly Ala Gly Thr Ile Tyr Val Thr
  65                  70                  75                  80

 gtc acg tta gtg aag ata aat gga gag aaa tat gcc ctg cca gct ggt      288
 Val Thr Leu Val Lys Ile Asn Gly Glu Lys Tyr Ala Leu Pro Ala Gly
                  85                  90                  95

 ggc act cag aaa gtg cca tgg agc agc aca gcc tgc gtc tca gaa tgg      336
 Gly Thr Gln Lys Val Pro Trp Ser Ser Thr Ala Cys Val Ser Glu Trp
             100                 105                 110

 aca gga aaa aag ctt tat ctt ctt cct gtc aaa gga ggg aaa tac ctt      384
 Thr Gly Lys Lys Leu Tyr Leu Leu Pro Val Lys Gly Gly Lys Tyr Leu
         115                 120                 125

 gtg gaa gac aac ttc aac tat ggc ctc tat gtg agg aca tca ctc tat      432
 Val Glu Asp Asn Phe Asn Tyr Gly Leu Tyr Val Arg Thr Ser Leu Tyr
     130                 135                 140

 ctt cag cct ttg cct ttc tcc tgg att cca ggg ctg cat tct tct ttc      480
 Leu Gln Pro Leu Pro Phe Ser Trp Ile Pro Gly Leu His Ser Ser Phe
 145                 150                 155                 160

 cag cct gac aac tgc agc cag tgc cca tgg cca ccg cag cgt cac cct      528
 Gln Pro Asp Asn Cys Ser Gln Cys Pro Trp Pro Pro Gln Arg His Pro
                 165                 170                 175

 gtc tac agc aag cat ctc ctg tga                                      552
 Val Tyr Ser Lys His Leu Leu 
             180





      <210> 472
      <211> 927
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(927)

      <400> 472
  atg ctg gga acc ttg ctc tgg atg cga ggc ctg ccc ctg gag gga gcc      48
  Met Leu Gly Thr Leu Leu Trp Met Arg Gly Leu Pro Leu Glu Gly Ala
    1               5                  10                  15

 gcg gag gac tgg cag ctg cag atg ctg gag cag gcc agc ctg tgg ctg       96
 Ala Glu Asp Trp Gln Leu Gln Met Leu Glu Gln Ala Ser Leu Trp Leu
              20                  25                  30

 ggc cgt agc ttc ctg ctg gca ggc ttc ctg gta tcg agc agc tgc ccc      144
 Gly Arg Ser Phe Leu Leu Ala Gly Phe Leu Val Ser Ser Ser Cys Pro
          35                  40                  45

 agc ctg gag cag gcg gcc aag ggt gag ggc tgt tcc ccc atc cct tgt      192
 Ser Leu Glu Gln Ala Ala Lys Gly Glu Gly Cys Ser Pro Ile Pro Cys
      50                  55                  60

 ttc gcc cac tgc ctc gac tcc ctg atg gtg gtc cgc gag gcg agt gcg      240
 Phe Ala His Cys Leu Asp Ser Leu Met Val Val Arg Glu Ala Ser Ala
  65                  70                  75                  80

 gca cag gcc tct ctg agc cag gtg ctg ccc cag ctg cgc tac ctg cac      288
 Ala Gln Ala Ser Leu Ser Gln Val Leu Pro Gln Leu Arg Tyr Leu His
                  85                  90                  95

 atc ttc ctg gag cag gtt cac aca cac ttt cag gag cag agt gtc ggg      336
 Ile Phe Leu Glu Gln Val His Thr His Phe Gln Glu Gln Ser Val Gly
             100                 105                 110

 gag agg ggc gca gcc atc cag ctg gct gag ggg ttg gcc cgg cag ctc      384
 Glu Arg Gly Ala Ala Ile Gln Leu Ala Glu Gly Leu Ala Arg Gln Leu
         115                 120                 125

 tgc acc gac tgt cag ctc aac aag ctc ttc tac cgc gag gag ttt gtg      432
 Cys Thr Asp Cys Gln Leu Asn Lys Leu Phe Tyr Arg Glu Glu Phe Val
     130                 135                 140

 ctg gcc acc ttg ctg gac cct tgc ttc aag ggg aag att gag gcc atc      480
 Leu Ala Thr Leu Leu Asp Pro Cys Phe Lys Gly Lys Ile Glu Ala Ile
 145                 150                 155                 160

 ctg cca tgg ggg ccg acc gac att gac cac tgg aag caa gtc ctc gtg      528
 Leu Pro Trp Gly Pro Thr Asp Ile Asp His Trp Lys Gln Val Leu Val
                 165                 170                 175

 tac aag gtg aag gag att aga gtg tct gaa tac tct ttg aac tcc cca      576
 Tyr Lys Val Lys Glu Ile Arg Val Ser Glu Tyr Ser Leu Asn Ser Pro
             180                 185                 190

 agt ccc ctg caa agc ccc agg ggt ctg tgc gtg gac ccc acc agg gta      624
 Ser Pro Leu Gln Ser Pro Arg Gly Leu Cys Val Asp Pro Thr Arg Val
         195                 200                 205

 gcc aag agc tcc ggg gtg gag ggg aga agc cag ggg gag cct ctg cag      672
 Ala Lys Ser Ser Gly Val Glu Gly Arg Ser Gln Gly Glu Pro Leu Gln
     210                 215                 220

 agc agc agc cac tct ggg gcc ttc ctg ctg gcc cag agg gag aag ggc      720
 Ser Ser Ser His Ser Gly Ala Phe Leu Leu Ala Gln Arg Glu Lys Gly
 225                 230                 235                 240

 ttg ctg gag agc atg ggg ctg ctg gcc tct gag aga agc ggg ggc tcg      768
 Leu Leu Glu Ser Met Gly Leu Leu Ala Ser Glu Arg Ser Gly Gly Ser
                 245                 250                 255

 ctg tcc acc aag agc cac tgg gcc agc atc att gtc aag aag tat ctg      816
 Leu Ser Thr Lys Ser His Trp Ala Ser Ile Ile Val Lys Lys Tyr Leu
             260                 265                 270

 tgg gag aat gag acc gtt gga gcc cag gat gac ccc ctg gct tac tgg      864
 Trp Glu Asn Glu Thr Val Gly Ala Gln Asp Asp Pro Leu Ala Tyr Trp
         275                 280                 285

 gag aag aag cga gaa gcc tgg cca cca tct atc tgt ctt acc ccc cac      912
 Glu Lys Lys Arg Glu Ala Trp Pro Pro Ser Ile Cys Leu Thr Pro His
     290                 295                 300

 agg agc ctt ctc tga                                                  927
 Arg Ser Leu Leu 
 305





      <210> 473
      <211> 330
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(330)

      <400> 473
  atg aag tgg aag gcg ctt ttc acc gcg gcc atc ctg cag gca cag ttg      48
  Met Lys Trp Lys Ala Leu Phe Thr Ala Ala Ile Leu Gln Ala Gln Leu
    1               5                  10                  15

 ccg att aca ggc ggc cat cta gcc cag cca gag ggc ccg gca ttg aca       96
 Pro Ile Thr Gly Gly His Leu Ala Gln Pro Glu Gly Pro Ala Leu Thr
              20                  25                  30

 gaa cac ggg gca gat gag acg atg tgc ctg gtt aag tca cca cca cga      144
 Glu His Gly Ala Asp Glu Thr Met Cys Leu Val Lys Ser Pro Pro Arg
          35                  40                  45

 gca gcg ccc agc caa caa gag tgc ttg ctc ctc acc tca ttc ccg atc      192
 Ala Ala Pro Ser Gln Gln Glu Cys Leu Leu Leu Thr Ser Phe Pro Ile
      50                  55                  60

 gtg gga gcc cag ctt tgc tgc aag cct tta gct tcc acc atg ttt tct      240
 Val Gly Ala Gln Leu Cys Cys Lys Pro Leu Ala Ser Thr Met Phe Ser
  65                  70                  75                  80

 agc cca gcc cag aaa cga ggt acg gta agg caa agc gcg act cag aga      288
 Ser Pro Ala Gln Lys Arg Gly Thr Val Arg Gln Ser Ala Thr Gln Arg
                  85                  90                  95

 ggc ctt gac acc gag ggc tgc gat ggt gct ttt gct gcc tga              330
 Gly Leu Asp Thr Glu Gly Cys Asp Gly Ala Phe Ala Ala 
             100                 105





      <210> 474
      <211> 729
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(729)

      <400> 474
  atg ttt ttg ctg cct gct gtg tgc tct gtg ctg ggt gct ggt gat tca      48
  Met Phe Leu Leu Pro Ala Val Cys Ser Val Leu Gly Ala Gly Asp Ser
    1               5                  10                  15

 gca gtg aag gaa cca gtc tgt cct cat gga gct aac agt gtt tgg ggg       96
 Ala Val Lys Glu Pro Val Cys Pro His Gly Ala Asn Ser Val Trp Gly
              20                  25                  30

 aag aca gca aat gca caa gca gcc atc tgc tgc cgg gtg gtg atg act      144
 Lys Thr Ala Asn Ala Gln Ala Ala Ile Cys Cys Arg Val Val Met Thr
          35                  40                  45

 ata gga aca tca gcc agg tgt agg aga gca gtg tcc agc aca gaa ttg      192
 Ile Gly Thr Ser Ala Arg Cys Arg Arg Ala Val Ser Ser Thr Glu Leu
      50                  55                  60

 tca gcc ctg gag aat ata tgt aaa gcc atc ata aaa gaa aag caa cct      240
 Ser Ala Leu Glu Asn Ile Cys Lys Ala Ile Ile Lys Glu Lys Gln Pro
  65                  70                  75                  80

 ttt gaa aga cta gaa gtc agc aag gaa atc ctc ctg gaa atg ttt aag      288
 Phe Glu Arg Leu Glu Val Ser Lys Glu Ile Leu Leu Glu Met Phe Lys
                  85                  90                  95

 tac aat aaa ttt aaa tgc cgc att ctg aat gag aaa gtt aac act gca      336
 Tyr Asn Lys Phe Lys Cys Arg Ile Leu Asn Glu Lys Val Asn Thr Ala
             100                 105                 110

 act acc acc gtg tac agg tgc ggt cca tta att gac ctt tgc aaa ggt      384
 Thr Thr Thr Val Tyr Arg Cys Gly Pro Leu Ile Asp Leu Cys Lys Gly
         115                 120                 125

 cca cat gta aga cac act gga aaa att aaa acc atc aaa att ttt aag      432
 Pro His Val Arg His Thr Gly Lys Ile Lys Thr Ile Lys Ile Phe Lys
     130                 135                 140

 aat tcc tca aca tat tgg gag ggc aat ccg gaa atg gaa aca ttg cag      480
 Asn Ser Ser Thr Tyr Trp Glu Gly Asn Pro Glu Met Glu Thr Leu Gln
 145                 150                 155                 160

 agg atc tat gga ata tcc ttt cct gat aac aag atg atg aga gac tgg      528
 Arg Ile Tyr Gly Ile Ser Phe Pro Asp Asn Lys Met Met Arg Asp Trp
                 165                 170                 175

 gaa aag ttc caa gag gaa gca aag aac cga gat cac agg aag atc ggg      576
 Glu Lys Phe Gln Glu Glu Ala Lys Asn Arg Asp His Arg Lys Ile Gly
             180                 185                 190

 aag cat gac tcc cag gtg att tgg cag ttc cag agg aaa gag gaa aaa      624
 Lys His Asp Ser Gln Val Ile Trp Gln Phe Gln Arg Lys Glu Glu Lys
         195                 200                 205

 acc aac agt gca aaa tac cta ctt gta tta caa gtt cat aga tgc aag      672
 Thr Asn Ser Ala Lys Tyr Leu Leu Val Leu Gln Val His Arg Cys Lys
     210                 215                 220

 aca gat gtg gct gat gaa cag gag cag ggc ctg att gtg agg gtc acc      720
 Thr Asp Val Ala Asp Glu Gln Glu Gln Gly Leu Ile Val Arg Val Thr
 225                 230                 235                 240

 aaa ctg taa                                                          729
 Lys Leu 






      <210> 475
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 475
  atg ggc ttt gtg ggg acg tgg gcc tgc ata gca ccc tgc ggg gca tct      48
  Met Gly Phe Val Gly Thr Trp Ala Cys Ile Ala Pro Cys Gly Ala Ser
    1               5                  10                  15

 cat atg agc gtg ctg ctg cat aac cgc tca cag tgc gtc cag aag ctg       96
 His Met Ser Val Leu Leu His Asn Arg Ser Gln Cys Val Gln Lys Leu
              20                  25                  30

 ggg atg cgc tgc ggc ctg cag ggg gcg cct cca ccg cgt gca gga tgg      144
 Gly Met Arg Cys Gly Leu Gln Gly Ala Pro Pro Pro Arg Ala Gly Trp
          35                  40                  45

 cct gct gcg acc agc tcc agg atc gca gtc acc tgc tgg ctc acc gcg      192
 Pro Ala Ala Thr Ser Ser Arg Ile Ala Val Thr Cys Trp Leu Thr Ala
      50                  55                  60

 atc ctc gtc ctg gcg ctg tgt gag gag gtc acg gtc tac agg atg aca      240
 Ile Leu Val Leu Ala Leu Cys Glu Glu Val Thr Val Tyr Arg Met Thr
  65                  70                  75                  80

 gga ggc aat aag cag cac agg acc tgg atc ctg ggg aca aga gaa aca      288
 Gly Gly Asn Lys Gln His Arg Thr Trp Ile Leu Gly Thr Arg Glu Thr
                  85                  90                  95

 ggc ctt ttg cct gga gag cct ttc cag gcc gtg gca tac gaa gat ggt      336
 Gly Leu Leu Pro Gly Glu Pro Phe Gln Ala Val Ala Tyr Glu Asp Gly
             100                 105                 110

 gtc gat gag acc aca gca aac ttg ctg act tga                          369
 Val Asp Glu Thr Thr Ala Asn Leu Leu Thr 
         115                 120





      <210> 476
      <211> 405
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(405)

      <400> 476
  atg aag gtc act agc ccc atg ctg ctg ctg gct gag ggc ctg ctg ccg      48
  Met Lys Val Thr Ser Pro Met Leu Leu Leu Ala Glu Gly Leu Leu Pro
    1               5                  10                  15

 gtg ctg gtg aga ggg act gga acc cac cct tca gcc tgc gac cct gac       96
 Val Leu Val Arg Gly Thr Gly Thr His Pro Ser Ala Cys Asp Pro Asp
              20                  25                  30

 ctg cac cct ccc cgc ccc atc cca ggc cag ggc ctt gag tgc ttc cag      144
 Leu His Pro Pro Arg Pro Ile Pro Gly Gln Gly Leu Glu Cys Phe Gln
          35                  40                  45

 tgc tac ggt gtc ctg gac ccc agc ctg tgt cac ccc gtc tcc tat ccc      192
 Cys Tyr Gly Val Leu Asp Pro Ser Leu Cys His Pro Val Ser Tyr Pro
      50                  55                  60

 atg cag gct caa agc tgc ccc tcc tct gtg gtc act ggc act atc gat      240
 Met Gln Ala Gln Ser Cys Pro Ser Ser Val Val Thr Gly Thr Ile Asp
  65                  70                  75                  80

 gaa att gag gat aga ctg att gac tcg aag att gag aag ctg gac atg      288
 Glu Ile Glu Asp Arg Leu Ile Asp Ser Lys Ile Glu Lys Leu Asp Met
                  85                  90                  95

 acc tgc tgt gaa aat agc ctc cgt aac aag gcg gcc aca gtg cgg cgt      336
 Thr Cys Cys Glu Asn Ser Leu Arg Asn Lys Ala Ala Thr Val Arg Arg
             100                 105                 110

 ggc ctc tgg tgc cag gct gtc agg gag ctc ctg ctc agc ctg agc ccc      384
 Gly Leu Trp Cys Gln Ala Val Arg Glu Leu Leu Leu Ser Leu Ser Pro
         115                 120                 125

 ttc ctc tgg gct ctg ctg tga                                          405
 Phe Leu Trp Ala Leu Leu 
     130





      <210> 477
      <211> 372
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(372)

      <400> 477
  atg gtg gcg tcg ttc cgt gag tct cgg gtt ttg ctt ctt ggg ttt gtg      48
  Met Val Ala Ser Phe Arg Glu Ser Arg Val Leu Leu Leu Gly Phe Val
    1               5                  10                  15

 gtc aga gtc ctt acc ttt gat ttc cta aca cag gtt gtt aga gtt gga       96
 Val Arg Val Leu Thr Phe Asp Phe Leu Thr Gln Val Val Arg Val Gly
              20                  25                  30

 agt gag tgt gga gat gag tta atc cga ctt tat tct ttc acg gat gag      144
 Ser Glu Cys Gly Asp Glu Leu Ile Arg Leu Tyr Ser Phe Thr Asp Glu
          35                  40                  45

 aaa gcg aat tat ctt cag caa ggg aat aac cac agg ccc atc cac aag      192
 Lys Ala Asn Tyr Leu Gln Gln Gly Asn Asn His Arg Pro Ile His Lys
      50                  55                  60

 gac cat ttc tgg ctg att tat gga aca ctg ttc tac ctg gtt aat ttt      240
 Asp His Phe Trp Leu Ile Tyr Gly Thr Leu Phe Tyr Leu Val Asn Phe
  65                  70                  75                  80

 gga cgt tat ctc agc ctg aga gac ggt ccc acc tgc agc gtg agg gcc      288
 Gly Arg Tyr Leu Ser Leu Arg Asp Gly Pro Thr Cys Ser Val Arg Ala
                  85                  90                  95

 cca tct gca gcc acc gag gag ctg gca gcc cca cag cat ttc ggt ttc      336
 Pro Ser Ala Ala Thr Glu Glu Leu Ala Ala Pro Gln His Phe Gly Phe
             100                 105                 110

 atc ccc ttc tct gca ccc gtc ctc atg aaa acc taa                      372
 Ile Pro Phe Ser Ala Pro Val Leu Met Lys Thr 
         115                 120





      <210> 478
      <211> 657
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(657)

      <400> 478
  atg ttg ctc aca caa agc ctg ttt ggt ggt ctc ttc aca cag acg cgc      48
  Met Leu Leu Thr Gln Ser Leu Phe Gly Gly Leu Phe Thr Gln Thr Arg
    1               5                  10                  15

 atg aaa ttt ggt gga tca ggg gac ctc cct tgg gag atc aat ccc ctg       96
 Met Lys Phe Gly Gly Ser Gly Asp Leu Pro Trp Glu Ile Asn Pro Leu
              20                  25                  30

 tcc tcc tgc tct ttg ctc cat gag aaa gct cca cct acc acc tca ggt      144
 Ser Ser Cys Ser Leu Leu His Glu Lys Ala Pro Pro Thr Thr Ser Gly
          35                  40                  45

 cct cag act gac cag ccc aag aaa cat ctc acc aat ttc aaa tcc gat      192
 Pro Gln Thr Asp Gln Pro Lys Lys His Leu Thr Asn Phe Lys Ser Asp
      50                  55                  60

 gtg gac aga gct gca gaa agg cat tta caa gga gtc atg ctg gct cag      240
 Val Asp Arg Ala Ala Glu Arg His Leu Gln Gly Val Met Leu Ala Gln
  65                  70                  75                  80

 atg ggt gaa gag gga act tta ttg acg tca gac cat gaa aag aga gtg      288
 Met Gly Glu Glu Gly Thr Leu Leu Thr Ser Asp His Glu Lys Arg Val
                  85                  90                  95

 ggc aat aaa ttc tgt ata gac aaa ggt gaa cac aat aaa ctg aga ctg      336
 Gly Asn Lys Phe Cys Ile Asp Lys Gly Glu His Asn Lys Leu Arg Leu
             100                 105                 110

 aca tat aaa cac gag tac aat tca aaa tac agt ggg aca aat gga gga      384
 Thr Tyr Lys His Glu Tyr Asn Ser Lys Tyr Ser Gly Thr Asn Gly Gly
         115                 120                 125

 cga gag cat ctg ggc agg ctc ctg gct gct gct gca ttc cag atg gaa      432
 Arg Glu His Leu Gly Arg Leu Leu Ala Ala Ala Ala Phe Gln Met Glu
     130                 135                 140

 gct aag gca gaa aca cga aga gca tgt gga ttg gac aat gga ggt ggg      480
 Ala Lys Ala Glu Thr Arg Arg Ala Cys Gly Leu Asp Asn Gly Gly Gly
 145                 150                 155                 160

 aag aag aca aag ggg aat aca cgt gtt tgg gca agg ggg tca ccc aac      528
 Lys Lys Thr Lys Gly Asn Thr Arg Val Trp Ala Arg Gly Ser Pro Asn
                 165                 170                 175

 aaa gag agg tgc tct gtt aat ttt ggg gga gaa aca ctg aat gcc aag      576
 Lys Glu Arg Cys Ser Val Asn Phe Gly Gly Glu Thr Leu Asn Ala Lys
             180                 185                 190

 cag gag aca acc aaa aat aaa ctt cgc tgc ctc tca gtt tta cca aag      624
 Gln Glu Thr Thr Lys Asn Lys Leu Arg Cys Leu Ser Val Leu Pro Lys
         195                 200                 205

 act aat aag gct tct ggg gat ctt cag aca tag                          657
 Thr Asn Lys Ala Ser Gly Asp Leu Gln Thr 
     210                 215





      <210> 479
      <211> 663
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(663)

      <400> 479
  atg ttt cta cag ttt gct tta gga aaa gtt gct atc ctt gct cat ttc      48
  Met Phe Leu Gln Phe Ala Leu Gly Lys Val Ala Ile Leu Ala His Phe
    1               5                  10                  15

 acg tat ttt gga aag aat ctg tcc ttt gcc aaa ggc tct agc ttc cga       96
 Thr Tyr Phe Gly Lys Asn Leu Ser Phe Ala Lys Gly Ser Ser Phe Arg
              20                  25                  30

 aga gct gac aac aaa ctc tgg gag ttg aca agc tcc tgg gtt cta ccc      144
 Arg Ala Asp Asn Lys Leu Trp Glu Leu Thr Ser Ser Trp Val Leu Pro
          35                  40                  45

 atg gct gct acc aca gta agt ttt tgg aaa ata tgg aaa gaa aaa acc      192
 Met Ala Ala Thr Thr Val Ser Phe Trp Lys Ile Trp Lys Glu Lys Thr
      50                  55                  60

 acc aaa acc cag gaa acc act acc ata cac caa aac aac aac aaa atc      240
 Thr Lys Thr Gln Glu Thr Thr Thr Ile His Gln Asn Asn Asn Lys Ile
  65                  70                  75                  80

 tac ttt gaa aca gtg aat tca ctc aag tat gaa tca ttg cct tac aaa      288
 Tyr Phe Glu Thr Val Asn Ser Leu Lys Tyr Glu Ser Leu Pro Tyr Lys
                  85                  90                  95

 atg aga caa aaa ggg cag gag aaa aag aca atc gaa gta ttc aag gaa      336
 Met Arg Gln Lys Gly Gln Glu Lys Lys Thr Ile Glu Val Phe Lys Glu
             100                 105                 110

 aac cag cag acg cgc gaa gcg tcg ggc cca ccc ggc ggc gcc gca ggc      384
 Asn Gln Gln Thr Arg Glu Ala Ser Gly Pro Pro Gly Gly Ala Ala Gly
         115                 120                 125

 cgt gca ccg cca ccc ccg gac cct ccc ccg cag att acc tcg cag cgc      432
 Arg Ala Pro Pro Pro Pro Asp Pro Pro Pro Gln Ile Thr Ser Gln Arg
     130                 135                 140

 gta gcc ggc ttt gtg ttt ccc ctc cct cct tct cgg cag ccg ccc ggg      480
 Val Ala Gly Phe Val Phe Pro Leu Pro Pro Ser Arg Gln Pro Pro Gly
 145                 150                 155                 160

 ctg cag cag ccg ccg gat ccg ccg ctg cgg ccg cct ctt aag cgc cgc      528
 Leu Gln Gln Pro Pro Asp Pro Pro Leu Arg Pro Pro Leu Lys Arg Arg
                 165                 170                 175

 aga gcc cca gag ggt gtg gat tct gca atg ctg cac aga aac cta ctg      576
 Arg Ala Pro Glu Gly Val Asp Ser Ala Met Leu His Arg Asn Leu Leu
             180                 185                 190

 cag cct cag acc aac agc agc agc agc agc ggc ggc ggc ggc agc agc      624
 Gln Pro Gln Thr Asn Ser Ser Ser Ser Ser Gly Gly Gly Gly Ser Ser
         195                 200                 205

 agc agc agc att agc agc agc agc ttc tct caa tgc tga                  663
 Ser Ser Ser Ile Ser Ser Ser Ser Phe Ser Gln Cys 
     210                 215                 220





      <210> 480
      <211> 294
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(294)

      <400> 480
  atg gtg ccc aga gcc ttg tgg aag ctg ctt cct atc ctg ggc tat ctg      48
  Met Val Pro Arg Ala Leu Trp Lys Leu Leu Pro Ile Leu Gly Tyr Leu
    1               5                  10                  15

 cag ccc gac ttg gga gtt gtg gtt act tca act gcc ata agg cat cct       96
 Gln Pro Asp Leu Gly Val Val Val Thr Ser Thr Ala Ile Arg His Pro
              20                  25                  30

 cct caa agt gca gag cag acc ctc ttg cct cta aag ttc ttt gac acc      144
 Pro Gln Ser Ala Glu Gln Thr Leu Leu Pro Leu Lys Phe Phe Asp Thr
          35                  40                  45

 aca ttc aca aat tca caa agg aaa gtt gct cct gac aca gag gca agg      192
 Thr Phe Thr Asn Ser Gln Arg Lys Val Ala Pro Asp Thr Glu Ala Arg
      50                  55                  60

 ctt tgg agt gac aag aaa cct aga gac aga aga agc tac tct gta ata      240
 Leu Trp Ser Asp Lys Lys Pro Arg Asp Arg Arg Ser Tyr Ser Val Ile
  65                  70                  75                  80

 att caa ctc agc act gaa gat tgt gta cca aag aag aga tgc cca cct      288
 Ile Gln Leu Ser Thr Glu Asp Cys Val Pro Lys Lys Arg Cys Pro Pro
                  85                  90                  95

 cct tag                                                              294
 Pro 






      <210> 481
      <211> 165
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(165)

      <400> 481
  atg tgc tcc atc ccc cgg cat ctg ctg cca ttg gtc ctg cct gtt gcg      48
  Met Cys Ser Ile Pro Arg His Leu Leu Pro Leu Val Leu Pro Val Ala
    1               5                  10                  15

 tta ctt ctc tgt gcc ctg gag ccc ctc aag cac aga ggc ctc gaa agg       96
 Leu Leu Leu Cys Ala Leu Glu Pro Leu Lys His Arg Gly Leu Glu Arg
              20                  25                  30

 ttg atc aga cat cct cag cac ctg gag cgg ggc ctg gca cac aag acg      144
 Leu Ile Arg His Pro Gln His Leu Glu Arg Gly Leu Ala His Lys Thr
          35                  40                  45

 gca atg aac ggc caa ccc tag                                          165
 Ala Met Asn Gly Gln Pro 
      50





      <210> 482
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 482
  atg gct ccg cta tcc att att cct act ctg tat gtc cat gtg tac cca      48
  Met Ala Pro Leu Ser Ile Ile Pro Thr Leu Tyr Val His Val Tyr Pro
    1               5                  10                  15

 ttg ctt cca ctt ata gca cca ttt att gaa aag ttg tcc gtc cac gtc       96
 Leu Leu Pro Leu Ile Ala Pro Phe Ile Glu Lys Leu Ser Val His Val
              20                  25                  30

 atc gag ggt gac cac cgc aca ctc ctg gag ggc agc ggc ctg gag tcc      144
 Ile Glu Gly Asp His Arg Thr Leu Leu Glu Gly Ser Gly Leu Glu Ser
          35                  40                  45

 atc atc agc acc ctg gct gag cca cgt gtg agc gtg cgg gag ggc tag      192
 Ile Ile Ser Thr Leu Ala Glu Pro Arg Val Ser Val Arg Glu Gly 
      50                  55                  60





      <210> 483
      <211> 735
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(735)

      <400> 483
  atg gcc cga gct gta cat tgg ccc ctt tta gtc atg gct gga gtg gct      48
  Met Ala Arg Ala Val His Trp Pro Leu Leu Val Met Ala Gly Val Ala
    1               5                  10                  15

 ggg aca cag ggc agg aaa tgg aaa ctt aaa aat gag gta acg cta cac       96
 Gly Thr Gln Gly Arg Lys Trp Lys Leu Lys Asn Glu Val Thr Leu His
              20                  25                  30

 atc cct tat atg gcc aaa atc cag aat acc aat gac acc aaa tac tgg      144
 Ile Pro Tyr Met Ala Lys Ile Gln Asn Thr Asn Asp Thr Lys Tyr Trp
          35                  40                  45

 cga gtg gag gaa cag gaa ttc tca ttc att gct gtg cgg tgc ttc tta      192
 Arg Val Glu Glu Gln Glu Phe Ser Phe Ile Ala Val Arg Cys Phe Leu
      50                  55                  60

 act gag acg acg cta aac tac cag aag atc ctt agt gtc cgt cca gga      240
 Thr Glu Thr Thr Leu Asn Tyr Gln Lys Ile Leu Ser Val Arg Pro Gly
  65                  70                  75                  80

 acc aaa ctc gcg acc gcc tcg cac gtg tca ggc cta gga cta cag aca      288
 Thr Lys Leu Ala Thr Ala Ser His Val Ser Gly Leu Gly Leu Gln Thr
                  85                  90                  95

 cca cct ttc ggc ctt gct cag cac ctc atc cgc ccc cac gcc ttc ctt      336
 Pro Pro Phe Gly Leu Ala Gln His Leu Ile Arg Pro His Ala Phe Leu
             100                 105                 110

 gcg ccc aaa gac ccc ctc acc tcc ttt aca gag aga aat tca aga agc      384
 Ala Pro Lys Asp Pro Leu Thr Ser Phe Thr Glu Arg Asn Ser Arg Ser
         115                 120                 125

 gga aag act aga tgc cga tcc aaa aag tgc gcg atg cga gta gtc aag      432
 Gly Lys Thr Arg Cys Arg Ser Lys Lys Cys Ala Met Arg Val Val Lys
     130                 135                 140

 tcg tac tcc gcc atc ttg cca aag aaa agg gag tct gtg ctc act aaa      480
 Ser Tyr Ser Ala Ile Leu Pro Lys Lys Arg Glu Ser Val Leu Thr Lys
 145                 150                 155                 160

 act tta ttg gta gcg ccg aca aac gaa cag aca gat cct gta ctg cgc      528
 Thr Leu Leu Val Ala Pro Thr Asn Glu Gln Thr Asp Pro Val Leu Arg
                 165                 170                 175

 atg tgc tgt ggt aaa act ggc cta aag aaa ggg gcg ggg ttt acc ctg      576
 Met Cys Cys Gly Lys Thr Gly Leu Lys Lys Gly Ala Gly Phe Thr Leu
             180                 185                 190

 gag agc aga gga caa cga cgc atg cgc gcg ggt tgt ccc acc ctt tgc      624
 Glu Ser Arg Gly Gln Arg Arg Met Arg Ala Gly Cys Pro Thr Leu Cys
         195                 200                 205

 gtt agg gcg cga gtg acg gaa aca gat ccc tct att tgt agg ttt gtc      672
 Val Arg Ala Arg Val Thr Glu Thr Asp Pro Ser Ile Cys Arg Phe Val
     210                 215                 220

 ggt atc ctc ttt cta atg ctg gcc ttc gat tac cag tca gtg gct tgc      720
 Gly Ile Leu Phe Leu Met Leu Ala Phe Asp Tyr Gln Ser Val Ala Cys
 225                 230                 235                 240

 agt cta ttc cgt taa                                                  735
 Ser Leu Phe Arg 






      <210> 484
      <211> 162
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(162)

      <400> 484
  atg ttc ttc tcc gcg gcg ctc cgg gcc cgg gcg gct ggc ctc acc gcc      48
  Met Phe Phe Ser Ala Ala Leu Arg Ala Arg Ala Ala Gly Leu Thr Ala
    1               5                  10                  15

 cac tgg atc agt ttc gaa gac cgt cgc tcc gaa gga ggc acc tct cgt       96
 His Trp Ile Ser Phe Glu Asp Arg Arg Ser Glu Gly Gly Thr Ser Arg
              20                  25                  30

 ttc aag cct agt gac ctc gat gct ttt agg ttg cag cat act gga gag      144
 Phe Lys Pro Ser Asp Leu Asp Ala Phe Arg Leu Gln His Thr Gly Glu
          35                  40                  45

 ctc tgg ctt gct tcg tga                                              162
 Leu Trp Leu Ala Ser 
      50





      <210> 485
      <211> 606
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(606)

      <400> 485
  atg tac tgg gcc agc acc acc ccc gcc acc agg gcg cac acg ctg gcg      48
  Met Tyr Trp Ala Ser Thr Thr Pro Ala Thr Arg Ala His Thr Leu Ala
    1               5                  10                  15

 ctc gct acc gcg acc acc ctc gcc acg gtc gcg cgg tgc atg gac ggg       96
 Leu Ala Thr Ala Thr Thr Leu Ala Thr Val Ala Arg Cys Met Asp Gly
              20                  25                  30

 gcc ctc atg agt gtc ccg gca gga aaa aaa cac cgc gat tgg gac tct      144
 Ala Leu Met Ser Val Pro Ala Gly Lys Lys His Arg Asp Trp Asp Ser
          35                  40                  45

 cag aag cgc agg atc cca gag cac cat gga caa gcc agt gac gcc ccg      192
 Gln Lys Arg Arg Ile Pro Glu His His Gly Gln Ala Ser Asp Ala Pro
      50                  55                  60

 ccc cca cta ggc ccc acc cac acg cac cga ggg gag agg gcg ggg agc      240
 Pro Pro Leu Gly Pro Thr His Thr His Arg Gly Glu Arg Ala Gly Ser
  65                  70                  75                  80

 ttc ttg ggg gaa tca ctc caa ctc tgt gga gct ggt ggt gct gcc tgg      288
 Phe Leu Gly Glu Ser Leu Gln Leu Cys Gly Ala Gly Gly Ala Ala Trp
                  85                  90                  95

 tgg ggc tct ctc ttt gcc cgg gac gtg gaa caa ctt tca gct gga gga      336
 Trp Gly Ser Leu Phe Ala Arg Asp Val Glu Gln Leu Ser Ala Gly Gly
             100                 105                 110

 cga gag gga ata gtg aag cta aag gtt gct ttt ctc tgc acc gtc cgt      384
 Arg Glu Gly Ile Val Lys Leu Lys Val Ala Phe Leu Cys Thr Val Arg
         115                 120                 125

 tct tgc tcc ctc tgc tcc atc act ggg acc ttg tca ggc gtt cat aaa      432
 Ser Cys Ser Leu Cys Ser Ile Thr Gly Thr Leu Ser Gly Val His Lys
     130                 135                 140

 gca aaa ttt gcc gaa cga ggg ttc gca gaa agg tgg ggc aga gct cat      480
 Ala Lys Phe Ala Glu Arg Gly Phe Ala Glu Arg Trp Gly Arg Ala His
 145                 150                 155                 160

 ctg acg tgg cat cag ata tcc cat cat gca cct ttt ccc ttt cct gat      528
 Leu Thr Trp His Gln Ile Ser His His Ala Pro Phe Pro Phe Pro Asp
                 165                 170                 175

 tat gct ttt cat cct ttt atc gta gcc atc ctt cat agc cat gaa gat      576
 Tyr Ala Phe His Pro Phe Ile Val Ala Ile Leu His Ser His Glu Asp
             180                 185                 190

 gac tat gct gtg tcc tgt gag tcc tcc tag                              606
 Asp Tyr Ala Val Ser Cys Glu Ser Ser 
         195                 200





      <210> 486
      <211> 642
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(642)

      <400> 486
  atg gtg ctg gtg gcc tgg cct ggt gcc ctg tgc tgg gta ggg gag gga      48
  Met Val Leu Val Ala Trp Pro Gly Ala Leu Cys Trp Val Gly Glu Gly
    1               5                  10                  15

 tac tgg cag cat ctc tgg ttt ggg gaa ggt gtt agg cca ccc agg tgt       96
 Tyr Trp Gln His Leu Trp Phe Gly Glu Gly Val Arg Pro Pro Arg Cys
              20                  25                  30

 ttt gca acc tgc ata gca ccg aac caa tgt aag ggc att ctt aaa gtt      144
 Phe Ala Thr Cys Ile Ala Pro Asn Gln Cys Lys Gly Ile Leu Lys Val
          35                  40                  45

 ttg gtg ttg atg aag gcc atg ctg atg agg aaa cta cct aaa tgg gca      192
 Leu Val Leu Met Lys Ala Met Leu Met Arg Lys Leu Pro Lys Trp Ala
      50                  55                  60

 cta ttc cag gaa ctg gac tgt cat gtt tca agg gat cct cag gtt gca      240
 Leu Phe Gln Glu Leu Asp Cys His Val Ser Arg Asp Pro Gln Val Ala
  65                  70                  75                  80

 aac tct gcg ctt atg tgc ctc aag aga cag ggc tct gga tgt atg agg      288
 Asn Ser Ala Leu Met Cys Leu Lys Arg Gln Gly Ser Gly Cys Met Arg
                  85                  90                  95

 tca agg ctg tct gaa gaa gat gaa tat ggt aga gat aag gag gat ttt      336
 Ser Arg Leu Ser Glu Glu Asp Glu Tyr Gly Arg Asp Lys Glu Asp Phe
             100                 105                 110

 cca gtg att gaa gag aga ctt cct agt caa gga ctg tgg ttt tgg agc      384
 Pro Val Ile Glu Glu Arg Leu Pro Ser Gln Gly Leu Trp Phe Trp Ser
         115                 120                 125

 agc agc agc agg gtc gtg ttc cct gtc tct ggc agt act ctg aac att      432
 Ser Ser Ser Arg Val Val Phe Pro Val Ser Gly Ser Thr Leu Asn Ile
     130                 135                 140

 ggc agg acc tca gag tgg tgg ccc aag gtg cct agg ctg cca gcc ttg      480
 Gly Arg Thr Ser Glu Trp Trp Pro Lys Val Pro Arg Leu Pro Ala Leu
 145                 150                 155                 160

 cca aaa ctt ccc ttc aat cag ctt ggt gag gaa gga gaa ggg gct gag      528
 Pro Lys Leu Pro Phe Asn Gln Leu Gly Glu Glu Gly Glu Gly Ala Glu
                 165                 170                 175

 gca gtg gga ttc tca gtg gat ggg aag act gag agg ata gaa ggt gta      576
 Ala Val Gly Phe Ser Val Asp Gly Lys Thr Glu Arg Ile Glu Gly Val
             180                 185                 190

 cgg caa gtg gct gag aag aga atg gga agg gca act gat gta ggc tcc      624
 Arg Gln Val Ala Glu Lys Arg Met Gly Arg Ala Thr Asp Val Gly Ser
         195                 200                 205

 att caa gaa gct tgt tag                                              642
 Ile Gln Glu Ala Cys 
     210





      <210> 487
      <211> 684
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(684)

      <400> 487
  atg ccc tgg gcg gcg tcc tcg ctg gcg atg ccc tgg gcg gcg tcc tcg      48
  Met Pro Trp Ala Ala Ser Ser Leu Ala Met Pro Trp Ala Ala Ser Ser
    1               5                  10                  15

 ctg gcg atg ccg tgg gcg gcg tcc tcg ctg gcg atg ccg tgg gcg gcg       96
 Leu Ala Met Pro Trp Ala Ala Ser Ser Leu Ala Met Pro Trp Ala Ala
              20                  25                  30

 tcc tcg ttg gcg atg ccc ttg tcg gcg gcc tcg tta gcg atg tcg tgt      144
 Ser Ser Leu Ala Met Pro Leu Ser Ala Ala Ser Leu Ala Met Ser Cys
          35                  40                  45

 aca gta tcc tcg tta gcg atg tca ctt tgg cca gtt gct gag caa att      192
 Thr Val Ser Ser Leu Ala Met Ser Leu Trp Pro Val Ala Glu Gln Ile
      50                  55                  60

 aac ttc aca act gaa gtg ggc cat act ggc ctt tgt ggt ccc cca ctc      240
 Asn Phe Thr Thr Glu Val Gly His Thr Gly Leu Cys Gly Pro Pro Leu
  65                  70                  75                  80

 ctc tta gaa ttt gtg agc gtg ggg cct act gga ggg aac tcg gga gct      288
 Leu Leu Glu Phe Val Ser Val Gly Pro Thr Gly Gly Asn Ser Gly Ala
                  85                  90                  95

 ggg gcc act ccc ttg gcc ctt cag gtt ctc cac ctg agc agt ggg gat      336
 Gly Ala Thr Pro Leu Ala Leu Gln Val Leu His Leu Ser Ser Gly Asp
             100                 105                 110

 aat aag gca gac ccg ggg atg gct ctg aaa tta ctt cta ggg atc tat      384
 Asn Lys Ala Asp Pro Gly Met Ala Leu Lys Leu Leu Leu Gly Ile Tyr
         115                 120                 125

 atg gta gag tcc atg gag aat tgt ttt aat tct tca ttc atg tct tca      432
 Met Val Glu Ser Met Glu Asn Cys Phe Asn Ser Ser Phe Met Ser Ser
     130                 135                 140

 gtg ggt ata gga ttg gtc ata ttg gtc ata gtt ttc tgc tcg gat ttc      480
 Val Gly Ile Gly Leu Val Ile Leu Val Ile Val Phe Cys Ser Asp Phe
 145                 150                 155                 160

 aat aag aaa ctt gtg gaa gaa cct gaa gga ttg tgg aag aga cat cca      528
 Asn Lys Lys Leu Val Glu Glu Pro Glu Gly Leu Trp Lys Arg His Pro
                 165                 170                 175

 gct gta gac act gag gtg cag gaa aac aat gga gca cca tca gag aaa      576
 Ala Val Asp Thr Glu Val Gln Glu Asn Asn Gly Ala Pro Ser Glu Lys
             180                 185                 190

 gca gtg ccc agg aac aag gag gca ctg atg gtg gca agg ggc aaa gac      624
 Ala Val Pro Arg Asn Lys Glu Ala Leu Met Val Ala Arg Gly Lys Asp
         195                 200                 205

 agc tgc cac gag gct gtt cac atg agg gtc tca ggc tgc ata gac acc      672
 Ser Cys His Glu Ala Val His Met Arg Val Ser Gly Cys Ile Asp Thr
     210                 215                 220

 cac acc agc tga                                                      684
 His Thr Ser 
 225





      <210> 488
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 488
  atg cct gga agg ttg act ctg ctt gcc agc gtg ctg gcc act ggc tgt      48
  Met Pro Gly Arg Leu Thr Leu Leu Ala Ser Val Leu Ala Thr Gly Cys
    1               5                  10                  15

 ata aag caa act ctc ctc ctt caa tac ctg act act tgc acc atc cag       96
 Ile Lys Gln Thr Leu Leu Leu Gln Tyr Leu Thr Thr Cys Thr Ile Gln
              20                  25                  30

 cag ata tcc tct act acc aag tct caa cag atg gtt cag ctg gtc ttt      144
 Gln Ile Ser Ser Thr Thr Lys Ser Gln Gln Met Val Gln Leu Val Phe
          35                  40                  45

 aat gaa caa aag gca ttt gtg taa                                      168
 Asn Glu Gln Lys Ala Phe Val 
      50                  55





      <210> 489
      <211> 471
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(471)

      <400> 489
  atg ccc ttc ctg acc ctt cag cta tac tca ctc ttt gtt gag tct tcc      48
  Met Pro Phe Leu Thr Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Ser
    1               5                  10                  15

 aca atc acc att gtt gct ggc cca gac ttc aat ccg gcc tcc cac att       96
 Thr Ile Thr Ile Val Ala Gly Pro Asp Phe Asn Pro Ala Ser His Ile
              20                  25                  30

 att cct gat acc aca cct gac ccc cat gac tgt atc tct ctg atc cac      144
 Ile Pro Asp Thr Thr Pro Asp Pro His Asp Cys Ile Ser Leu Ile His
          35                  40                  45

 ctg aca ttc att cca ttt ccc cat att tcc ttc ttt cct gtt cct cac      192
 Leu Thr Phe Ile Pro Phe Pro His Ile Ser Phe Phe Pro Val Pro His
      50                  55                  60

 cct gat cac act tgg ttt att gat ggc agt tcc acc agg cct aat tgc      240
 Pro Asp His Thr Trp Phe Ile Asp Gly Ser Ser Thr Arg Pro Asn Cys
  65                  70                  75                  80

 cac tca cca gca aag gca ggc tat gct ata gta tct tcc aca ttt atc      288
 His Ser Pro Ala Lys Ala Gly Tyr Ala Ile Val Ser Ser Thr Phe Ile
                  85                  90                  95

 att gag gct act gcc ctg ccc ccc tcc act acc tct cag caa gcc aaa      336
 Ile Glu Ala Thr Ala Leu Pro Pro Ser Thr Thr Ser Gln Gln Ala Lys
             100                 105                 110

 ctc att gcc tta act cag gcc ctc act ctt gca aag gga cta ctt gtc      384
 Leu Ile Ala Leu Thr Gln Ala Leu Thr Leu Ala Lys Gly Leu Leu Val
         115                 120                 125

 aat att tat act gat tct aaa tat gcc ttc cat atc cag tac cac cat      432
 Asn Ile Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Gln Tyr His His
     130                 135                 140

 gct gtt ata tgg gca gaa aga aat ttc ctc act aca taa                  471
 Ala Val Ile Trp Ala Glu Arg Asn Phe Leu Thr Thr 
 145                 150                 155





      <210> 490
      <211> 366
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(366)

      <400> 490
  atg acc ctg ggg ttt ggg ctg tcg agg cgg cca tca ctt ctg gtg ggc      48
  Met Thr Leu Gly Phe Gly Leu Ser Arg Arg Pro Ser Leu Leu Val Gly
    1               5                  10                  15

 ggc ctg gag ccc aga ctc tgg cat cag gca gat ctg gct gct gac cag       96
 Gly Leu Glu Pro Arg Leu Trp His Gln Ala Asp Leu Ala Ala Asp Gln
              20                  25                  30

 ctg agt gag gtt ggg cag gga ggt ttt aac aac atc aca cct gtt ttc      144
 Leu Ser Glu Val Gly Gln Gly Gly Phe Asn Asn Ile Thr Pro Val Phe
          35                  40                  45

 aaa cgg gga aac tgc atc gag gga gga gaa ggc act tgt caa ggt cac      192
 Lys Arg Gly Asn Cys Ile Glu Gly Gly Glu Gly Thr Cys Gln Gly His
      50                  55                  60

 acg gat gat aaa cgc agg gct ctc agc tgc cag cca acc aag cag atg      240
 Thr Asp Asp Lys Arg Arg Ala Leu Ser Cys Gln Pro Thr Lys Gln Met
  65                  70                  75                  80

 gtg caa caa cca gac cta aag gaa gga cct ggg gaa gaa gag aaa ggg      288
 Val Gln Gln Pro Asp Leu Lys Glu Gly Pro Gly Glu Glu Glu Lys Gly
                  85                  90                  95

 agc ctg gca agt ctg agc ttt ggg agt ggg tct gga cct cgt gac cat      336
 Ser Leu Ala Ser Leu Ser Phe Gly Ser Gly Ser Gly Pro Arg Asp His
             100                 105                 110

 tac tcc atc tgc tac ccc acg ctt cct tag                              366
 Tyr Ser Ile Cys Tyr Pro Thr Leu Pro 
         115                 120





      <210> 491
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 491
  atg agt cgg ttg cct gtg gca cat ctt tca gtg tgc att ttg gga ttt      48
  Met Ser Arg Leu Pro Val Ala His Leu Ser Val Cys Ile Leu Gly Phe
    1               5                  10                  15

 gtg aat gtg ctt aac cag aaa atg cca gaa tac agt caa tcc acc aac       96
 Val Asn Val Leu Asn Gln Lys Met Pro Glu Tyr Ser Gln Ser Thr Asn
              20                  25                  30

 ctg tca gtg gtg ctc ttc ttg tgg gat cat gtg caa agt ttg aac agt      144
 Leu Ser Val Val Leu Phe Leu Trp Asp His Val Gln Ser Leu Asn Ser
          35                  40                  45

 atc acc tgc gtt tct acg gtc atc aag ctg aat tgc tcg tgg gga tgt      192
 Ile Thr Cys Val Ser Thr Val Ile Lys Leu Asn Cys Ser Trp Gly Cys
      50                  55                  60

 tac ctg tgg ctg act tca atg act tga                                  219
 Tyr Leu Trp Leu Thr Ser Met Thr 
  65                  70





      <210> 492
      <211> 546
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(546)

      <400> 492
  atg gac aag ttt tgg tgg cac gca gcc tgg gga ctc tgc ctc gtg ccg      48
  Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val Pro
    1               5                  10                  15

 ctg agc ctg gcg cag atc ggt gag tgc ccg ccg cag cct ggg cag caa       96
 Leu Ser Leu Ala Gln Ile Gly Glu Cys Pro Pro Gln Pro Gly Gln Gln
              20                  25                  30

 gat ggg tgc ggg gtg ctc agc gcg gac ccg gcg gca gcc cct ccg gct      144
 Asp Gly Cys Gly Val Leu Ser Ala Asp Pro Ala Ala Ala Pro Pro Ala
          35                  40                  45

 gag tcg gcc ctg ggg gac tgg agt caa cct cag agc aga gag aag agc      192
 Glu Ser Ala Leu Gly Asp Trp Ser Gln Pro Gln Ser Arg Glu Lys Ser
      50                  55                  60

 ctt gat acc agg gca aca tca ggg acc ctg gag cta ggg ctc caa tat      240
 Leu Asp Thr Arg Ala Thr Ser Gly Thr Leu Glu Leu Gly Leu Gln Tyr
  65                  70                  75                  80

 ctc atc caa aca ggg tca gtg ctt tgt ggt ggc tat gga ggg gag ggg      288
 Leu Ile Gln Thr Gly Ser Val Leu Cys Gly Gly Tyr Gly Gly Glu Gly
                  85                  90                  95

 ctg cgt gta agt ctc agg tat gtc ttt atc agc agc agg aaa acg aat      336
 Leu Arg Val Ser Leu Arg Tyr Val Phe Ile Ser Ser Arg Lys Thr Asn
             100                 105                 110

 gaa tac agt aaa ttg gga cca gtc aag tgg gga gtt gct gaa aag ata      384
 Glu Tyr Ser Lys Leu Gly Pro Val Lys Trp Gly Val Ala Glu Lys Ile
         115                 120                 125

 ccc aaa aat gtg gaa aca gct ttg gaa ctg ggt aac agg ccc cac ttc      432
 Pro Lys Asn Val Glu Thr Ala Leu Glu Leu Gly Asn Arg Pro His Phe
     130                 135                 140

 caa ata ttt ggc act gtc cta acc ctt gag gtt ctc cca gag acc cgc      480
 Gln Ile Phe Gly Thr Val Leu Thr Leu Glu Val Leu Pro Glu Thr Arg
 145                 150                 155                 160

 agt ctc cct cct gcc ccg tgt ttc cac ggc ccc ttt gcg cag cat cat      528
 Ser Leu Pro Pro Ala Pro Cys Phe His Gly Pro Phe Ala Gln His His
                 165                 170                 175

 tta gag gaa gta caa tga                                              546
 Leu Glu Glu Val Gln 
             180





      <210> 493
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(498)

      <400> 493
  atg cca ggg ccc aca ggg aca aag ttt tcg att ttt gtg ttt tgg gtg      48
  Met Pro Gly Pro Thr Gly Thr Lys Phe Ser Ile Phe Val Phe Trp Val
    1               5                  10                  15

 gca gta ctc tca cac cag gat gac tgg gtc tta gca cga cct aat cgt       96
 Ala Val Leu Ser His Gln Asp Asp Trp Val Leu Ala Arg Pro Asn Arg
              20                  25                  30

 ctt cat gat gga aag aaa gca aag caa ctg att gcc cag aga aaa ctg      144
 Leu His Asp Gly Lys Lys Ala Lys Gln Leu Ile Ala Gln Arg Lys Leu
          35                  40                  45

 gaa gat cgg tgg tgc atc cga ggc agg gct gag tta gaa cag gac atc      192
 Glu Asp Arg Trp Cys Ile Arg Gly Arg Ala Glu Leu Glu Gln Asp Ile
      50                  55                  60

 cta gac tcg gcg gca gtg act att att cag aaa tgg cac atc aag ggc      240
 Leu Asp Ser Ala Ala Val Thr Ile Ile Gln Lys Trp His Ile Lys Gly
  65                  70                  75                  80

 cgg cct gcc ctt cat cct gca ggg gta ctt ggg cat gtg gag gcc cct      288
 Arg Pro Ala Leu His Pro Ala Gly Val Leu Gly His Val Glu Ala Pro
                  85                  90                  95

 ttc tcc ctg gtg ttg caa ctg gag agg agt cgg ttc ctg aag aac aga      336
 Phe Ser Leu Val Leu Gln Leu Glu Arg Ser Arg Phe Leu Lys Asn Arg
             100                 105                 110

 tgg gag agt gct ggg gcc agg tac cct ggg aga gag gag gga aat gaa      384
 Trp Glu Ser Ala Gly Ala Arg Tyr Pro Gly Arg Glu Glu Gly Asn Glu
         115                 120                 125

 atc cgg cac agg ggc tgc ggg gat cgg ggc agt cag gag gcg gca gtg      432
 Ile Arg His Arg Gly Cys Gly Asp Arg Gly Ser Gln Glu Ala Ala Val
     130                 135                 140

 cgg tgc aag ggc ccc ccc acg cgg cca gct gtg gaa ctt cca cca cga      480
 Arg Cys Lys Gly Pro Pro Thr Arg Pro Ala Val Glu Leu Pro Pro Arg
 145                 150                 155                 160

 ctc cct gtc ctc tcc tga                                              498
 Leu Pro Val Leu Ser 
                 165





      <210> 494
      <211> 747
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(747)

      <400> 494
  atg tcc atc aag ttg ttc ctc cag act gtg gtg ccc ctt ctt tgt ggt      48
  Met Ser Ile Lys Leu Phe Leu Gln Thr Val Val Pro Leu Leu Cys Gly
    1               5                  10                  15

 tcc att ctg acc ttt ggc ctc tgg ata ggg acc ctc ctg ccg gcc cct       96
 Ser Ile Leu Thr Phe Gly Leu Trp Ile Gly Thr Leu Leu Pro Ala Pro
              20                  25                  30

 acc agt gtc aaa aac cac cag gag aag ctt cca gga tgg aga aaa gag      144
 Thr Ser Val Lys Asn His Gln Glu Lys Leu Pro Gly Trp Arg Lys Glu
          35                  40                  45

 aag gac ctg tct ctc tgg ctg tcc ctc agt aag cag cag aag aga aat      192
 Lys Asp Leu Ser Leu Trp Leu Ser Leu Ser Lys Gln Gln Lys Arg Asn
      50                  55                  60

 agc tgg acc ctg atg ttc cat aaa cac aag ccg gtg gcg agc cca gtg      240
 Ser Trp Thr Leu Met Phe His Lys His Lys Pro Val Ala Ser Pro Val
  65                  70                  75                  80

 agg aag gct gtg gga gag gaa gcg gga gca gag agg gca aca ccc cac      288
 Arg Lys Ala Val Gly Glu Glu Ala Gly Ala Glu Arg Ala Thr Pro His
                  85                  90                  95

 aat ctg gat atg gca acc ctt agt tac acg cga gac ggc tct gag agt      336
 Asn Leu Asp Met Ala Thr Leu Ser Tyr Thr Arg Asp Gly Ser Glu Ser
             100                 105                 110

 agc gtg tgg att caa gaa cac gtc ctc gag tgg aac gcc aaa gaa gat      384
 Ser Val Trp Ile Gln Glu His Val Leu Glu Trp Asn Ala Lys Glu Asp
         115                 120                 125

 gcc tgc tct agg ggc cag agc gcg ctc cga gca cga agc ccg ggg cgg      432
 Ala Cys Ser Arg Gly Gln Ser Ala Leu Arg Ala Arg Ser Pro Gly Arg
     130                 135                 140

 gcc gtc atc cag gcg cag ggc tgg aac aaa gct gga ttt cca gtt cag      480
 Ala Val Ile Gln Ala Gln Gly Trp Asn Lys Ala Gly Phe Pro Val Gln
 145                 150                 155                 160

 acc cca atc ggg ccc atc aat acg agg ggc tgg acc cgc aca aaa gac      528
 Thr Pro Ile Gly Pro Ile Asn Thr Arg Gly Trp Thr Arg Thr Lys Asp
                 165                 170                 175

 atg cgg att gtc tgg ggc tgc aga cat gtg cag gca aaa aag ctg gct      576
 Met Arg Ile Val Trp Gly Cys Arg His Val Gln Ala Lys Lys Leu Ala
             180                 185                 190

 cag cag att gcc tgc ctg gag gat ttt gga tgg aag gca agt tca gag      624
 Gln Gln Ile Ala Cys Leu Glu Asp Phe Gly Trp Lys Ala Ser Ser Glu
         195                 200                 205

 tct cat cat tta aaa gac ctg ctc tct tcg aaa gta atg aca gtt gtg      672
 Ser His His Leu Lys Asp Leu Leu Ser Ser Lys Val Met Thr Val Val
     210                 215                 220

 gct cgg aac atg gtc acc agc agt tac caa gag cac att tct aag atc      720
 Ala Arg Asn Met Val Thr Ser Ser Tyr Gln Glu His Ile Ser Lys Ile
 225                 230                 235                 240

 ctc tac cac aga agg aca aag acc tga                                  747
 Leu Tyr His Arg Arg Thr Lys Thr 
                 245





      <210> 495
      <211> 555
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(555)

      <400> 495
  atg gtg att ccc gtg gcc ttc ttg ccc ttg cct ctc acg tgc ctg gca      48
  Met Val Ile Pro Val Ala Phe Leu Pro Leu Pro Leu Thr Cys Leu Ala
    1               5                  10                  15

 aca tgg ctg ccc cca cat aac ccc aca tgt gta gaa cat cac ggt gcc       96
 Thr Trp Leu Pro Pro His Asn Pro Thr Cys Val Glu His His Gly Ala
              20                  25                  30

 ctg cat ttg caa att aaa agg cta ggg tgg gag agc cag tgt ttt gca      144
 Leu His Leu Gln Ile Lys Arg Leu Gly Trp Glu Ser Gln Cys Phe Ala
          35                  40                  45

 ggc tac gtg aat gac acg cct ggt caa acc aat ccc gtg aac tct atg      192
 Gly Tyr Val Asn Asp Thr Pro Gly Gln Thr Asn Pro Val Asn Ser Met
      50                  55                  60

 caa atc aaa cac cac ctc ctc cag cgt ctt cat ata cct ggc tgt ggt      240
 Gln Ile Lys His His Leu Leu Gln Arg Leu His Ile Pro Gly Cys Gly
  65                  70                  75                  80

 tgt cat tgg ctg aaa ccg caa gaa agc caa agg aaa ggg gtc tca gac      288
 Cys His Trp Leu Lys Pro Gln Glu Ser Gln Arg Lys Gly Val Ser Asp
                  85                  90                  95

 cca ctt gat gca atc tgc aga ggt cag ctt cct gag ctc aga aaa gaa      336
 Pro Leu Asp Ala Ile Cys Arg Gly Gln Leu Pro Glu Leu Arg Lys Glu
             100                 105                 110

 gac aga aat gcc gac agg gga tct gga agg aga atg gag aaa gtt cag      384
 Asp Arg Asn Ala Asp Arg Gly Ser Gly Arg Arg Met Glu Lys Val Gln
         115                 120                 125

 tgc acc acc agt ttc tgg gac ata gaa ttc tgg tta ccc gtt ggc act      432
 Cys Thr Thr Ser Phe Trp Asp Ile Glu Phe Trp Leu Pro Val Gly Thr
     130                 135                 140

 tat gaa ttt acc tat cga ata cca ttt gta aat gtc ctc atc att tac      480
 Tyr Glu Phe Thr Tyr Arg Ile Pro Phe Val Asn Val Leu Ile Ile Tyr
 145                 150                 155                 160

 cta gtg ccc gag tgt cac tgc aga cca cgt gcc ttc atc tct gta cac      528
 Leu Val Pro Glu Cys His Cys Arg Pro Arg Ala Phe Ile Ser Val His
                 165                 170                 175

 atc tgt gct ggc tgc aga gaa cag tga                                  555
 Ile Cys Ala Gly Cys Arg Glu Gln 
             180





      <210> 496
      <211> 966
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(966)

      <400> 496
  atg atg atc gcg ggt atc gct gcg ctg ctg ttg tgg ctt ctg gtg ctg      48
  Met Met Ile Ala Gly Ile Ala Ala Leu Leu Leu Trp Leu Leu Val Leu
    1               5                  10                  15

 gct gct ccc att gct ggg gaa ctt gca gct gca gtc cgg agg cct gga       96
 Ala Ala Pro Ile Ala Gly Glu Leu Ala Ala Ala Val Arg Arg Pro Gly
              20                  25                  30

 ccg cgc gct cca ttc ccg aca gga atg ggg gaa cgg aat tct gga ttc      144
 Pro Arg Ala Pro Phe Pro Thr Gly Met Gly Glu Arg Asn Ser Gly Phe
          35                  40                  45

 gtg gag ctc tcc ggc cgc tgg ggc cgg gtg ttc aca gtg cgg ctg ggc      192
 Val Glu Leu Ser Gly Arg Trp Gly Arg Val Phe Thr Val Arg Leu Gly
      50                  55                  60

 ccg cgc cct gcg gtg gtg ctg tgc ggc tac gca gcg ctg cgg gac gcg      240
 Pro Arg Pro Ala Val Val Leu Cys Gly Tyr Ala Ala Leu Arg Asp Ala
  65                  70                  75                  80

 tta gtg cta cag gcg gat gcg gtc tcc ggc cgc ggg tcc atg gca gtc      288
 Leu Val Leu Gln Ala Asp Ala Val Ser Gly Arg Gly Ser Met Ala Val
                  85                  90                  95

 ttc gaa cgc ttc aca cgc gga aac aga atc ttg ttt tct aac cgg ccg      336
 Phe Glu Arg Phe Thr Arg Gly Asn Arg Ile Leu Phe Ser Asn Arg Pro
             100                 105                 110

 tgc tgg tgg aca ctg cgc aat ttt gca ctt gga gcg ccg aag aag ttc      384
 Cys Trp Trp Thr Leu Arg Asn Phe Ala Leu Gly Ala Pro Lys Lys Phe
         115                 120                 125

 ggg ttg ggt acg cgg acc atc gag gcg cgt gtc ctg gat gag gcg gct      432
 Gly Leu Gly Thr Arg Thr Ile Glu Ala Arg Val Leu Asp Glu Ala Ala
     130                 135                 140

 tgt ctg cta gac gaa ttt caa gcc acc att gct tcg gcc tgg ccg gga      480
 Cys Leu Leu Asp Glu Phe Gln Ala Thr Ile Ala Ser Ala Trp Pro Gly
 145                 150                 155                 160

 ggg cga aag ggc ctg gtg tgg gag tgg ccc ttg gac tgc caa gat ggg      528
 Gly Arg Lys Gly Leu Val Trp Glu Trp Pro Leu Asp Cys Gln Asp Gly
                 165                 170                 175

 gcc acg gga aag tat ttg ggt gga aga aag cca gta agc cca tgg ggc      576
 Ala Thr Gly Lys Tyr Leu Gly Gly Arg Lys Pro Val Ser Pro Trp Gly
             180                 185                 190

 tgg ctg ggg gca gga cca cgc gtt atg acc acc gtc ctg ttc cta ccc      624
 Trp Leu Gly Ala Gly Pro Arg Val Met Thr Thr Val Leu Phe Leu Pro
         195                 200                 205

 cca ggg gcc ccg ttt gac ccc gtg cgg cta ctg ggt aat gct gta tcc      672
 Pro Gly Ala Pro Phe Asp Pro Val Arg Leu Leu Gly Asn Ala Val Ser
     210                 215                 220

 aat gtt acc tgt tct tgt ctt cgg gaa ccg cta tgg cta cgg gga ccc      720
 Asn Val Thr Cys Ser Cys Leu Arg Glu Pro Leu Trp Leu Arg Gly Pro
 225                 230                 235                 240

 gga gtt cct gag gtc ctg aac ctc cta agt gac aac ttc cgc atc atg      768
 Gly Val Pro Glu Val Leu Asn Leu Leu Ser Asp Asn Phe Arg Ile Met
                 245                 250                 255

 agt tcc aaa tgg ggc gag ggg cag gag ctg gac cct gtg gta ggg cag      816
 Ser Ser Lys Trp Gly Glu Gly Gln Glu Leu Asp Pro Val Val Gly Gln
             260                 265                 270

 agg cct gtc cca agc ccg gac gac cac gtg caa tgg ccc tac acc aac      864
 Arg Pro Val Pro Ser Pro Asp Asp His Val Gln Trp Pro Tyr Thr Asn
         275                 280                 285

 gca gtg ctg ctg gag atc cag cgc ttc atc agc gtg gtg ccg cgc acc      912
 Ala Val Leu Leu Glu Ile Gln Arg Phe Ile Ser Val Val Pro Arg Thr
     290                 295                 300

 ctc acc ctc gac acc cac ctg cac agc cac tgt ctg gcc aaa ggt gcc      960
 Leu Thr Leu Asp Thr His Leu His Ser His Cys Leu Ala Lys Gly Ala
 305                 310                 315                 320

 cac tga                                                              966
 His 






      <210> 497
      <211> 732
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(732)

      <400> 497
  atg aga act aaa acc cag caa cta aga ttt agg caa aga aaa cag att      48
  Met Arg Thr Lys Thr Gln Gln Leu Arg Phe Arg Gln Arg Lys Gln Ile
    1               5                  10                  15

 cca gaa tca gca cag agc ctg ctg ctg ctg ctg ctg ctt ctg tct gct       96
 Pro Glu Ser Ala Gln Ser Leu Leu Leu Leu Leu Leu Leu Leu Ser Ala
              20                  25                  30

 gct tct gct gct gga ggc att gct aac aca ctc acc caa gcc tta gct      144
 Ala Ser Ala Ala Gly Gly Ile Ala Asn Thr Leu Thr Gln Ala Leu Ala
          35                  40                  45

 ctt aat aga gac atg ttt gca gct gaa tgc ccc agg tca gaa att gca      192
 Leu Asn Arg Asp Met Phe Ala Ala Glu Cys Pro Arg Ser Glu Ile Ala
      50                  55                  60

 gtg gag att act acc act gaa ctg gga tcc tta aat gca atg gac ttt      240
 Val Glu Ile Thr Thr Thr Glu Leu Gly Ser Leu Asn Ala Met Asp Phe
  65                  70                  75                  80

 gga ata gct ggg acc aag tgg tgg caa tta atg cca aag acc aga ttt      288
 Gly Ile Ala Gly Thr Lys Trp Trp Gln Leu Met Pro Lys Thr Arg Phe
                  85                  90                  95

 tat tta aat gga tgg atg ttt ctc tta atg tgt tct gcg gct gaa ttc      336
 Tyr Leu Asn Gly Trp Met Phe Leu Leu Met Cys Ser Ala Ala Glu Phe
             100                 105                 110

 agt gtt cag gcc ctg act ggg gct cag aaa ctg cga ttc att ttt atc      384
 Ser Val Gln Ala Leu Thr Gly Ala Gln Lys Leu Arg Phe Ile Phe Ile
         115                 120                 125

 agc agc agt gta act gcc cct ggg gcc tca ggt tcc agg aac cac tta      432
 Ser Ser Ser Val Thr Ala Pro Gly Ala Ser Gly Ser Arg Asn His Leu
     130                 135                 140

 cag gtg gct tta aag gtg agg ctg gtt cga cct aca gtc aac agg aag      480
 Gln Val Ala Leu Lys Val Arg Leu Val Arg Pro Thr Val Asn Arg Lys
 145                 150                 155                 160

 ctc ctg ggg gca ggg aca gga tcc ctg cct cgg aag gag gca aga cgt      528
 Leu Leu Gly Ala Gly Thr Gly Ser Leu Pro Arg Lys Glu Ala Arg Arg
                 165                 170                 175

 gaa cgt ttt ttg gac ggc gat cag gat ggt gat gag ggt ccc aga caa      576
 Glu Arg Phe Leu Asp Gly Asp Gln Asp Gly Asp Glu Gly Pro Arg Gln
             180                 185                 190

 cct tct atg gga ctg cca cat aag caa gtc caa aac cga gca atg gca      624
 Pro Ser Met Gly Leu Pro His Lys Gln Val Gln Asn Arg Ala Met Ala
         195                 200                 205

 aaa gtg gta att act ttt gca cca act aat gca atg caa cta gcc agg      672
 Lys Val Val Ile Thr Phe Ala Pro Thr Asn Ala Met Gln Leu Ala Arg
     210                 215                 220

 tcg cct aaa aca ctt aat ttc atg aaa ata att ggg gag atg gag tct      720
 Ser Pro Lys Thr Leu Asn Phe Met Lys Ile Ile Gly Glu Met Glu Ser
 225                 230                 235                 240

 gtt cta gaa taa                                                      732
 Val Leu Glu 






      <210> 498
      <211> 291
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(291)

      <400> 498
  atg ggc atg tcc tta gtt gcc atc ctg gta ctg aca gca aaa ccc cat      48
  Met Gly Met Ser Leu Val Ala Ile Leu Val Leu Thr Ala Lys Pro His
    1               5                  10                  15

 ggg tcc aag caa cag aag gtg gtc act aat cag gga ttt tcg agc ccg       96
 Gly Ser Lys Gln Gln Lys Val Val Thr Asn Gln Gly Phe Ser Ser Pro
              20                  25                  30

 ttg ctt aag gcc gtc gtt gac cca aag gat aca gca gga atg atg ggc      144
 Leu Leu Lys Ala Val Val Asp Pro Lys Asp Thr Ala Gly Met Met Gly
          35                  40                  45

 cct gct gat aag gtg aag aaa gtg acc cga ggg ggc aaa ctt aca gac      192
 Pro Ala Asp Lys Val Lys Lys Val Thr Arg Gly Gly Lys Leu Thr Asp
      50                  55                  60

 ggg aca tac ttt ggc aaa ata aca aaa cag cgg gac ctg aag gct ggc      240
 Gly Thr Tyr Phe Gly Lys Ile Thr Lys Gln Arg Asp Leu Lys Ala Gly
  65                  70                  75                  80

 ttc cca agc gtc ctc gag gcc ttg tgc cag gaa gag gac cct cgg gct      288
 Phe Pro Ser Val Leu Glu Ala Leu Cys Gln Glu Glu Asp Pro Arg Ala
                  85                  90                  95

 tag                                                                  291
 






      <210> 499
      <211> 528
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(528)

      <400> 499
  atg cgg ctg ccg agt ctg gtt ttg tgg aca aag caa act gtg gaa tgg      48
  Met Arg Leu Pro Ser Leu Val Leu Trp Thr Lys Gln Thr Val Glu Trp
    1               5                  10                  15

 ctt ctc ggt gtc tgt ata aag gga caa acg gtt gca ttc acc ctt tgt       96
 Leu Leu Gly Val Cys Ile Lys Gly Gln Thr Val Ala Phe Thr Leu Cys
              20                  25                  30

 act ata aca ccg ctt ctg cat tcg cca tat ccg ttt ttt aac ctt ttt      144
 Thr Ile Thr Pro Leu Leu His Ser Pro Tyr Pro Phe Phe Asn Leu Phe
          35                  40                  45

 gtc tcc ggg gaa ctt ctc att cga tta tta tgt ctt ctg atg att tgc      192
 Val Ser Gly Glu Leu Leu Ile Arg Leu Leu Cys Leu Leu Met Ile Cys
      50                  55                  60

 cat gtt att tta aag ggc aca ggg gcc ctg gga cgt ggt tgg cag cca      240
 His Val Ile Leu Lys Gly Thr Gly Ala Leu Gly Arg Gly Trp Gln Pro
  65                  70                  75                  80

 ggc tgc gag aga gct aaa aag gaa caa gaa cat cag ctc gga tgt ttg      288
 Gly Cys Glu Arg Ala Lys Lys Glu Gln Glu His Gln Leu Gly Cys Leu
                  85                  90                  95

 tct ctc agc cct gac acc tgc cac tct cct tcc cgg ggc act tgg ccc      336
 Ser Leu Ser Pro Asp Thr Cys His Ser Pro Ser Arg Gly Thr Trp Pro
             100                 105                 110

 tat cag agg gac atg aaa tgc tgt ccg aat ggt ggc aga aat gca gcg      384
 Tyr Gln Arg Asp Met Lys Cys Cys Pro Asn Gly Gly Arg Asn Ala Ala
         115                 120                 125

 aca ttg cat gca gca gag tct ttg ctt cga aag atg ggg cgc cat gtt      432
 Thr Leu His Ala Ala Glu Ser Leu Leu Arg Lys Met Gly Arg His Val
     130                 135                 140

 tca gag aac att tat ctt agt ccc acg ttc agt tca tac aaa ggc act      480
 Ser Glu Asn Ile Tyr Leu Ser Pro Thr Phe Ser Ser Tyr Lys Gly Thr
 145                 150                 155                 160

 gta tgg ggg cct gct ggc ttg gtg ggc cca gcg gac cgt gag cat tag      528
 Val Trp Gly Pro Ala Gly Leu Val Gly Pro Ala Asp Arg Glu His 
                 165                 170                 175





      <210> 500
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 500
  atg aga cca aag atc aca gat gga tct ggc tct gca ttt cag tgg gac      48
  Met Arg Pro Lys Ile Thr Asp Gly Ser Gly Ser Ala Phe Gln Trp Asp
    1               5                  10                  15

 tta gca agg ttt tgg cac caa ttc tgt caa tta act aca ata ctg tac       96
 Leu Ala Arg Phe Trp His Gln Phe Cys Gln Leu Thr Thr Ile Leu Tyr
              20                  25                  30

 tgg ctc tgg tac tgc atc ttc tac agt gca tgt aac gat atg tac aag      144
 Trp Leu Trp Tyr Cys Ile Phe Tyr Ser Ala Cys Asn Asp Met Tyr Lys
          35                  40                  45

 gga ctt cta tca aca aag gtc agt gtc atg tgt gaa tca ccg ggt ttc      192
 Gly Leu Leu Ser Thr Lys Val Ser Val Met Cys Glu Ser Pro Gly Phe
      50                  55                  60

 ctt aac tga                                                          201
 Leu Asn 
  65





      <210> 501
      <211> 591
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(591)

      <400> 501
  atg gtc caa gac gca ggt tct tgt ggt agc ctg gca ccg ccc cgg ccc      48
  Met Val Gln Asp Ala Gly Ser Cys Gly Ser Leu Ala Pro Pro Arg Pro
    1               5                  10                  15

 ctc gtc ctc ctg ttg ctc acc cgg ttt gcc cag gct gcc agc agt gat       96
 Leu Val Leu Leu Leu Leu Thr Arg Phe Ala Gln Ala Ala Ser Ser Asp
              20                  25                  30

 ggc tgg ggg ctc tgc tat cct cag cac caa gcc acg tcc gtg ggt gcc      144
 Gly Trp Gly Leu Cys Tyr Pro Gln His Gln Ala Thr Ser Val Gly Ala
          35                  40                  45

 cac ggg cag gca aga cag ctg ggc cct tgg gtg tgg ccc tgg ccc gac      192
 His Gly Gln Ala Arg Gln Leu Gly Pro Trp Val Trp Pro Trp Pro Asp
      50                  55                  60

 gca cct tcc aca ggg tca cgg ctc ctc ctc ctg ctg ctc agc tcc atg      240
 Ala Pro Ser Thr Gly Ser Arg Leu Leu Leu Leu Leu Leu Ser Ser Met
  65                  70                  75                  80

 gac tcg cta gat tgc atg gtt ggt gta agt gac cag tgt aac tgg aag      288
 Asp Ser Leu Asp Cys Met Val Gly Val Ser Asp Gln Cys Asn Trp Lys
                  85                  90                  95

 ccc act aac aca ggc aga agt ttg gtg tcc aac tat cag tct atc aca      336
 Pro Thr Asn Thr Gly Arg Ser Leu Val Ser Asn Tyr Gln Ser Ile Thr
             100                 105                 110

 tgt gga cga agc aaa ctg ctt gag gat ggg agt tgg gtg gag tca gtg      384
 Cys Gly Arg Ser Lys Leu Leu Glu Asp Gly Ser Trp Val Glu Ser Val
         115                 120                 125

 gcc tat gag ctc cct gtc aac aga aaa att caa gca gac gat gaa gaa      432
 Ala Tyr Glu Leu Pro Val Asn Arg Lys Ile Gln Ala Asp Asp Glu Glu
     130                 135                 140

 tca ctt agc cgg atg gtg gtg ggc aag ttt caa ggt tta tgt gct acc      480
 Ser Leu Ser Arg Met Val Val Gly Lys Phe Gln Gly Leu Cys Ala Thr
 145                 150                 155                 160

 tgg aca ggt gcc aat gga aga aaa tgg tgc cac aac atc caa aaa aag      528
 Trp Thr Gly Ala Asn Gly Arg Lys Trp Cys His Asn Ile Gln Lys Lys
                 165                 170                 175

 aat aag aac aca gca tgg cac ctt aca gct cat gaa gaa ttc cca cct      576
 Asn Lys Asn Thr Ala Trp His Leu Thr Ala His Glu Glu Phe Pro Pro
             180                 185                 190

 tca tct ctg aaa tga                                                  591
 Ser Ser Leu Lys 
         195





      <210> 502
      <211> 624
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(624)

      <400> 502
  atg cct ttg caa agg tgg atc ttc aga gga gaa gga ctg tgt gta tgg      48
  Met Pro Leu Gln Arg Trp Ile Phe Arg Gly Glu Gly Leu Cys Val Trp
    1               5                  10                  15

 ctg aag gag tgg acc ctg agc act ggg cag gcc ttt caa ggt gcc agt       96
 Leu Lys Glu Trp Thr Leu Ser Thr Gly Gln Ala Phe Gln Gly Ala Ser
              20                  25                  30

 caa ctt cag tgt aaa cca aca gct tta gct ggg aga ggc cca gtg ccc      144
 Gln Leu Gln Cys Lys Pro Thr Ala Leu Ala Gly Arg Gly Pro Val Pro
          35                  40                  45

 cac atg gcc ctg cat ggc aca cag gaa cag tgg cag gtg gtc atg gag      192
 His Met Ala Leu His Gly Thr Gln Glu Gln Trp Gln Val Val Met Glu
      50                  55                  60

 cca gcc tcc ctc atc aac acc att ccc act agg aaa tgt tca gga gtg      240
 Pro Ala Ser Leu Ile Asn Thr Ile Pro Thr Arg Lys Cys Ser Gly Val
  65                  70                  75                  80

 gtg ttg tcc aat aca atc gcc act agc tgc tgc gac tac cga gca ctc      288
 Val Leu Ser Asn Thr Ile Ala Thr Ser Cys Cys Asp Tyr Arg Ala Leu
                  85                  90                  95

 agt gtg ggg ctg gaa ttg aga tgt gct cca agc aga ctc ctc tca act      336
 Ser Val Gly Leu Glu Leu Arg Cys Ala Pro Ser Arg Leu Leu Ser Thr
             100                 105                 110

 gcg tgc cgg cag caa aaa ctc cag att tct ggt cgc tcc aaa ggc tgt      384
 Ala Cys Arg Gln Gln Lys Leu Gln Ile Ser Gly Arg Ser Lys Gly Cys
         115                 120                 125

 tct aga aaa acc tct ggt ctg gag gac caa ggc cta act aaa gat gca      432
 Ser Arg Lys Thr Ser Gly Leu Glu Asp Gln Gly Leu Thr Lys Asp Ala
     130                 135                 140

 gag ccc aag cat tct act ttt tca ttt agt gga ttg tcc cct ctc tgt      480
 Glu Pro Lys His Ser Thr Phe Ser Phe Ser Gly Leu Ser Pro Leu Cys
 145                 150                 155                 160

 ggg aga ggg ccc ctc aga ccc atg ggc acc ttg gag gtg ttc tat gcc      528
 Gly Arg Gly Pro Leu Arg Pro Met Gly Thr Leu Glu Val Phe Tyr Ala
                 165                 170                 175

 aag gtg cca act gca tcc ggc acg gtg ctt tcc ttg ctg ggc tgg act      576
 Lys Val Pro Thr Ala Ser Gly Thr Val Leu Ser Leu Leu Gly Trp Thr
             180                 185                 190

 tca gaa aat ggc aga gcg cca gac ttt ggc caa tgc caa ggg cac tga      624
 Ser Glu Asn Gly Arg Ala Pro Asp Phe Gly Gln Cys Gln Gly His 
         195                 200                 205





      <210> 503
      <211> 177
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(177)

      <400> 503
  atg gat ttc agt gcc ctc atc tgg cca acc atc ttc agc tgc caa tgg      48
  Met Asp Phe Ser Ala Leu Ile Trp Pro Thr Ile Phe Ser Cys Gln Trp
    1               5                  10                  15

 gca agt gtc ttc ctg gta cta cac atg aag atg tcc cgc tct cca ctg       96
 Ala Ser Val Phe Leu Val Leu His Met Lys Met Ser Arg Ser Pro Leu
              20                  25                  30

 ctc aag gag aga gtg cct gac ctg agc tgg gcc cat cag atc cag tac      144
 Leu Lys Glu Arg Val Pro Asp Leu Ser Trp Ala His Gln Ile Gln Tyr
          35                  40                  45

 tta cct gga ata cga aaa aga tgg aga gag tga                          177
 Leu Pro Gly Ile Arg Lys Arg Trp Arg Glu 
      50                  55





      <210> 504
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 504
  atg gag gag gaa acc agg gtg cac att tct aca gat ccc ctt tgc ctg      48
  Met Glu Glu Glu Thr Arg Val His Ile Ser Thr Asp Pro Leu Cys Leu
    1               5                  10                  15

 ctg gtg ttt gcc tta ctt ttg tgc tgt agt aag aat gtc tta gaa gtt       96
 Leu Val Phe Ala Leu Leu Leu Cys Cys Ser Lys Asn Val Leu Glu Val
              20                  25                  30

 gtg tct tcg agt tcc tca aac acc gga cag ggc tcc ccc aga gct gcc      144
 Val Ser Ser Ser Ser Ser Asn Thr Gly Gln Gly Ser Pro Arg Ala Ala
          35                  40                  45

 tca gcc ttt gat ttg gtc cat att cag aca ctt cct gtc ttg cat aca      192
 Ser Ala Phe Asp Leu Val His Ile Gln Thr Leu Pro Val Leu His Thr
      50                  55                  60

 ctc tga                                                              198
 Leu 
  65





      <210> 505
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 505
  atg cca ggt ctt act ctc caa ggc tac gtt atc ctg caa att ctg gtg      48
  Met Pro Gly Leu Thr Leu Gln Gly Tyr Val Ile Leu Gln Ile Leu Val
    1               5                  10                  15

 gac ctg gga gac acc cta tct cca atc agg tgg agg agg cac gtg acc       96
 Asp Leu Gly Asp Thr Leu Ser Pro Ile Arg Trp Arg Arg His Val Thr
              20                  25                  30

 cac atg gtc tgg cca ctg atg act gaa caa gct atg gac acc gga ccc      144
 His Met Val Trp Pro Leu Met Thr Glu Gln Ala Met Asp Thr Gly Pro
          35                  40                  45

 cgg aga gac cat tca ctc act ggc cac gaa cat gag ttc aga tac atg      192
 Arg Arg Asp His Ser Leu Thr Gly His Glu His Glu Phe Arg Tyr Met
      50                  55                  60

 ccc caa aag gat gag cct ggc tgg ttc tgc aat cag cag ccc ctc cag      240
 Pro Gln Lys Asp Glu Pro Gly Trp Phe Cys Asn Gln Gln Pro Leu Gln
  65                  70                  75                  80

 aca tcc ctg gga ggc tcc aag gag ctg act cct gat gag gaa aag gat      288
 Thr Ser Leu Gly Gly Ser Lys Glu Leu Thr Pro Asp Glu Glu Lys Asp
                  85                  90                  95

 cag ccg cag act cac tcc tcc tcc agc cac ttc cag acc cac ggg agg      336
 Gln Pro Gln Thr His Ser Ser Ser Ser His Phe Gln Thr His Gly Arg
             100                 105                 110

 cgg cag gac cct ctg aag gag gag ccc tca gag aag aag gga aaa gcc      384
 Arg Gln Asp Pro Leu Lys Glu Glu Pro Ser Glu Lys Lys Gly Lys Ala
         115                 120                 125

 aaa agg aat taa                                                      396
 Lys Arg Asn 
     130





      <210> 506
      <211> 177
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(177)

      <400> 506
  atg aat gac aaa gca att ttt aaa aca ttg ttt ttg ttt ttt cct cag      48
  Met Asn Asp Lys Ala Ile Phe Lys Thr Leu Phe Leu Phe Phe Pro Gln
    1               5                  10                  15

 tcc ttg gtt ttg atc agc aaa cta cct tat att cat ttt ttt cac act       96
 Ser Leu Val Leu Ile Ser Lys Leu Pro Tyr Ile His Phe Phe His Thr
              20                  25                  30

 gtg ctc aaa cag ata gca cca gag tat ttt gaa aag aat gaa cct tat      144
 Val Leu Lys Gln Ile Ala Pro Glu Tyr Phe Glu Lys Asn Glu Pro Tyr
          35                  40                  45

 ttg gaa gca ggt acg gat tcc cac atg tca tga                          177
 Leu Glu Ala Gly Thr Asp Ser His Met Ser 
      50                  55





      <210> 507
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 507
  atg gta ttc cac aca gca ttg cct ctg acc aag gca ctc act tta cgg      48
  Met Val Phe His Thr Ala Leu Pro Leu Thr Lys Ala Leu Thr Leu Arg
    1               5                  10                  15

 cta aag aat tgc aac agt ggg ctc atg ctc acg gaa ttc act ggt ctt       96
 Leu Lys Asn Cys Asn Ser Gly Leu Met Leu Thr Glu Phe Thr Gly Leu
              20                  25                  30

 acc atg ttc ccc atc atc cag ggt tgg ggc aaa gtt ctc cag aag gcc      144
 Thr Met Phe Pro Ile Ile Gln Gly Trp Gly Lys Val Leu Gln Lys Ala
          35                  40                  45

 gtg tat gct ctg aat cag cgt cca ata tat ggt gct gtt tct ccc aca      192
 Val Tyr Ala Leu Asn Gln Arg Pro Ile Tyr Gly Ala Val Ser Pro Thr
      50                  55                  60

 gac agg att cat atg tcc agg aat caa ggg gtg gaa gtg gaa gtg gca      240
 Asp Arg Ile His Met Ser Arg Asn Gln Gly Val Glu Val Glu Val Ala
  65                  70                  75                  80

 cca ctc acc atc acc cct ggt gat cca cta gca aaa gtt ttg ctt cct      288
 Pro Leu Thr Ile Thr Pro Gly Asp Pro Leu Ala Lys Val Leu Leu Pro
                  85                  90                  95

 ttt cct gtg aca tta ctt tct gct ggc tag                              318
 Phe Pro Val Thr Leu Leu Ser Ala Gly 
             100                 105





      <210> 508
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 508
  atg gag ttc ttt tgt tgg ttt tgg gat ttc tgg ggt tgg ctg ctt aat      48
  Met Glu Phe Phe Cys Trp Phe Trp Asp Phe Trp Gly Trp Leu Leu Asn
    1               5                  10                  15

 atg att aga ccc aaa gat gct aag gac cct cct tct aat agt atg gag       96
 Met Ile Arg Pro Lys Asp Ala Lys Asp Pro Pro Ser Asn Ser Met Glu
              20                  25                  30

 aac act gat agt cct cgt tgt gaa ctg ttt aga gag tta tgc aaa ata      144
 Asn Thr Asp Ser Pro Arg Cys Glu Leu Phe Arg Glu Leu Cys Lys Ile
          35                  40                  45

 aat gca ttt gac act cct gat tca ctg ctc atg aga gac aag gag ttt      192
 Asn Ala Phe Asp Thr Pro Asp Ser Leu Leu Met Arg Asp Lys Glu Phe
      50                  55                  60

 agt gac ttt gta cat aat atc ttt gac cat atg tgg aga acc aag gaa      240
 Ser Asp Phe Val His Asn Ile Phe Asp His Met Trp Arg Thr Lys Glu
  65                  70                  75                  80

 cat aat gaa gct ggt tgg ttg ctt cta agt ttg gtg gat aaa gtg atg      288
 His Asn Glu Ala Gly Trp Leu Leu Leu Ser Leu Val Asp Lys Val Met
                  85                  90                  95

 aaa gaa aac tat gaa ctc agg gat tct gtc tcc tgg ctt cag aag cag      336
 Lys Glu Asn Tyr Glu Leu Arg Asp Ser Val Ser Trp Leu Gln Lys Gln
             100                 105                 110

 ata atg agc ctt aaa tat gct aac att gcc ctg agt gag agt ctt atc      384
 Ile Met Ser Leu Lys Tyr Ala Asn Ile Ala Leu Ser Glu Ser Leu Ile
         115                 120                 125

 tcc tgt aga gaa aga gct aaa att gtg aaa aaa cag aca caa gtg gct      432
 Ser Cys Arg Glu Arg Ala Lys Ile Val Lys Lys Gln Thr Gln Val Ala
     130                 135                 140

 gac ctg caa tga                                                      444
 Asp Leu Gln 
 145





      <210> 509
      <211> 210
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(210)

      <400> 509
  atg atg gcc tac ttg gtt gtt tct ggg cta ttc cta act cga ctt cga      48
  Met Met Ala Tyr Leu Val Val Ser Gly Leu Phe Leu Thr Arg Leu Arg
    1               5                  10                  15

 aga ccc att gaa agc tcc aga aac aaa aag ggg cca tct cgc ctg gtg       96
 Arg Pro Ile Glu Ser Ser Arg Asn Lys Lys Gly Pro Ser Arg Leu Val
              20                  25                  30

 tgt ctt tat gag agc aaa gaa acc ttt ccc aag agt ccc aca act gac      144
 Cys Leu Tyr Glu Ser Lys Glu Thr Phe Pro Lys Ser Pro Thr Thr Asp
          35                  40                  45

 ttt ccc tca tat ctt att ggc tgg aat ggt tac ttg acc atg cct aaa      192
 Phe Pro Ser Tyr Leu Ile Gly Trp Asn Gly Tyr Leu Thr Met Pro Lys
      50                  55                  60

 gca atc aca gca aag tga                                              210
 Ala Ile Thr Ala Lys 
  65





      <210> 510
      <211> 921
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(921)

      <400> 510
  atg ggg ttg ctg ccc agg gcc ccc ttg ggt ctc tgc ttt ctg cat ccc      48
  Met Gly Leu Leu Pro Arg Ala Pro Leu Gly Leu Cys Phe Leu His Pro
    1               5                  10                  15

 agt gca gca ctc ctc agc cac ccc agc tgt ggc tca agc gac ccc aag       96
 Ser Ala Ala Leu Leu Ser His Pro Ser Cys Gly Ser Ser Asp Pro Lys
              20                  25                  30

 tgc agc tca acc cag cac tcc aga agt gac cag gtc aag act atc cca      144
 Cys Ser Ser Thr Gln His Ser Arg Ser Asp Gln Val Lys Thr Ile Pro
          35                  40                  45

 gcc ttc tcc aac aaa tct aat aca cgc aca tac aca ctc cac cct tcg      192
 Ala Phe Ser Asn Lys Ser Asn Thr Arg Thr Tyr Thr Leu His Pro Ser
      50                  55                  60

 ccc tat aca gaa aaa aat cac cat cgg aag gga gca cct gaa gga aat      240
 Pro Tyr Thr Glu Lys Asn His His Arg Lys Gly Ala Pro Glu Gly Asn
  65                  70                  75                  80

 tct tca gcc cca tcc tca cac cta cct gct ctg gca tgc atc tgc ata      288
 Ser Ser Ala Pro Ser Ser His Leu Pro Ala Leu Ala Cys Ile Cys Ile
                  85                  90                  95

 cat cca cac aca gcg aat cct cta cct gca ctc atg ggc caa gat cag      336
 His Pro His Thr Ala Asn Pro Leu Pro Ala Leu Met Gly Gln Asp Gln
             100                 105                 110

 ggt gca gag atc aag ggc aag aac agg gaa cag aga tgc aga acg caa      384
 Gly Ala Glu Ile Lys Gly Lys Asn Arg Glu Gln Arg Cys Arg Thr Gln
         115                 120                 125

 ttg tct cta gag aaa tac ctc aca tac act att gtc acc tac gtc ctt      432
 Leu Ser Leu Glu Lys Tyr Leu Thr Tyr Thr Ile Val Thr Tyr Val Leu
     130                 135                 140

 gtc cat gtc ccc cag cag act caa ctc ctg ggt gtc tct ggc atc tct      480
 Val His Val Pro Gln Gln Thr Gln Leu Leu Gly Val Ser Gly Ile Ser
 145                 150                 155                 160

 ggc atc tgt aca aag atg cta tct ctg aag tca gga gta gcc cac agt      528
 Gly Ile Cys Thr Lys Met Leu Ser Leu Lys Ser Gly Val Ala His Ser
                 165                 170                 175

 cct gtt gca cat gaa aat ccg gaa ttc ttc gta aga ctg gat gga acc      576
 Pro Val Ala His Glu Asn Pro Glu Phe Phe Val Arg Leu Asp Gly Thr
             180                 185                 190

 ctc aca tac aat gat gca gcc gtt ttg gaa aac agt ttg gca gtc gtt      624
 Leu Thr Tyr Asn Asp Ala Ala Val Leu Glu Asn Ser Leu Ala Val Val
         195                 200                 205

 caa aag gtt aag tgc aga gtt act aca tgg ccc tgc agt tct act cct      672
 Gln Lys Val Lys Cys Arg Val Thr Thr Trp Pro Cys Ser Ser Thr Pro
     210                 215                 220

 atg gga atg tat gtt cac aca aaa act tgt aca cga atg ctc aca gta      720
 Met Gly Met Tyr Val His Thr Lys Thr Cys Thr Arg Met Leu Thr Val
 225                 230                 235                 240

 acg cca ttt gta cta gct aaa gtc agg ctt act gct tct aga aga gag      768
 Thr Pro Phe Val Leu Ala Lys Val Arg Leu Thr Ala Ser Arg Arg Glu
                 245                 250                 255

 cag aga gtg tca ggg agt gag act gca ttt ctg ggc tta gaa gta aag      816
 Gln Arg Val Ser Gly Ser Glu Thr Ala Phe Leu Gly Leu Glu Val Lys
             260                 265                 270

 gat gtg aga ctt gtt cag tat ttg cca tca gca cag gga aaa cca gga      864
 Asp Val Arg Leu Val Gln Tyr Leu Pro Ser Ala Gln Gly Lys Pro Gly
         275                 280                 285

 gaa agc ctg gct cca gga cct gga ggc ttc tgc ccc gta cga tca gaa      912
 Glu Ser Leu Ala Pro Gly Pro Gly Gly Phe Cys Pro Val Arg Ser Glu
     290                 295                 300

 ggt gga tag                                                          921
 Gly Gly 
 305





      <210> 511
      <211> 807
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(807)

      <400> 511
  atg ctc ctt cca cgg aaa ctg acc ctg tcc tat ttc ctc gct ttg atc      48
  Met Leu Leu Pro Arg Lys Leu Thr Leu Ser Tyr Phe Leu Ala Leu Ile
    1               5                  10                  15

 att gcc cag aag gaa cag gga ctg ttg aga aac aga ggc agc gtg cag       96
 Ile Ala Gln Lys Glu Gln Gly Leu Leu Arg Asn Arg Gly Ser Val Gln
              20                  25                  30

 cct gaa ggc atg cac cgt gca gaa gag gat ccc tgc ggc tgc ggg ctc      144
 Pro Glu Gly Met His Arg Ala Glu Glu Asp Pro Cys Gly Cys Gly Leu
          35                  40                  45

 ttt tcc agg ccc aag gac aag gcg gtg tgt gcc ggg ttg atc tgc act      192
 Phe Ser Arg Pro Lys Asp Lys Ala Val Cys Ala Gly Leu Ile Cys Thr
      50                  55                  60

 gct tta gcc agg atg gct ctt ctt aga gag aca aac cgc tcc aac gcc      240
 Ala Leu Ala Arg Met Ala Leu Leu Arg Glu Thr Asn Arg Ser Asn Ala
  65                  70                  75                  80

 aaa ctg ccc tcg caa ttc caa tcg caa agg cag gct agg gcc aca gtt      288
 Lys Leu Pro Ser Gln Phe Gln Ser Gln Arg Gln Ala Arg Ala Thr Val
                  85                  90                  95

 caa acc caa ctg cca atg tcc aca aag aaa aga aga aag ctg gaa atg      336
 Gln Thr Gln Leu Pro Met Ser Thr Lys Lys Arg Arg Lys Leu Glu Met
             100                 105                 110

 cag ttg gtc ttg cca tgc tgg ccg ctc agc ttc tca ccc cca ggc cta      384
 Gln Leu Val Leu Pro Cys Trp Pro Leu Ser Phe Ser Pro Pro Gly Leu
         115                 120                 125

 aga agg aca agc tgt gtg tgt tgg aag gag ggt gat gag gtc att cag      432
 Arg Arg Thr Ser Cys Val Cys Trp Lys Glu Gly Asp Glu Val Ile Gln
     130                 135                 140

 ttg aat aaa cca gga acc aat acc acc aag agg aat gaa cgc atc act      480
 Leu Asn Lys Pro Gly Thr Asn Thr Thr Lys Arg Asn Glu Arg Ile Thr
 145                 150                 155                 160

 gag ccc agc tgt cct gat gcg cgt gaa tgg ggg ccc gtg ggc tgg ggc      528
 Glu Pro Ser Cys Pro Asp Ala Arg Glu Trp Gly Pro Val Gly Trp Gly
                 165                 170                 175

 aga gct gcc cgt gac ccc cgg aca cgg acc cat gaa ggg agc atc tca      576
 Arg Ala Ala Arg Asp Pro Arg Thr Arg Thr His Glu Gly Ser Ile Ser
             180                 185                 190

 aat cgc cca ggt ggg gta gac ctg ggc ccg ctg gga ctc acc agc agc      624
 Asn Arg Pro Gly Gly Val Asp Leu Gly Pro Leu Gly Leu Thr Ser Ser
         195                 200                 205

 cat ggt gaa gac act gat gct gag gac aca tca gaa agg gcc tgg gga      672
 His Gly Glu Asp Thr Asp Ala Glu Asp Thr Ser Glu Arg Ala Trp Gly
     210                 215                 220

 aag ctg act cgc agg cgt aac atg tcg ctc ccc tgc tcc cgc cat ggt      720
 Lys Leu Thr Arg Arg Arg Asn Met Ser Leu Pro Cys Ser Arg His Gly
 225                 230                 235                 240

 gtt cca ggg aaa cca gct tcc gag ctg tac ttc aga gcc ctc tgc aaa      768
 Val Pro Gly Lys Pro Ala Ser Glu Leu Tyr Phe Arg Ala Leu Cys Lys
                 245                 250                 255

 cag tgc tac cta gac aag aga acg cag agc aac gcc tga                  807
 Gln Cys Tyr Leu Asp Lys Arg Thr Gln Ser Asn Ala 
             260                 265





      <210> 512
      <211> 1062
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1062)

      <400> 512
  atg gga ttc tgg ttc tta aac tgg aca aga agt gct ttc cag ggg gat      48
  Met Gly Phe Trp Phe Leu Asn Trp Thr Arg Ser Ala Phe Gln Gly Asp
    1               5                  10                  15

 gtg gct ttg cac cct gtg gac aac aat gac aga cag acc cat ggt cat       96
 Val Ala Leu His Pro Val Asp Asn Asn Asp Arg Gln Thr His Gly His
              20                  25                  30

 ccc agg ctc tca ctg gtc cag ctg gaa gtg ggg ggc tca gag ggc cac      144
 Pro Arg Leu Ser Leu Val Gln Leu Glu Val Gly Gly Ser Glu Gly His
          35                  40                  45

 aga act cgt gtg gta aag gcc gag gaa ctg tca ctc tca ggt tcc att      192
 Arg Thr Arg Val Val Lys Ala Glu Glu Leu Ser Leu Ser Gly Ser Ile
      50                  55                  60

 gca gtg atc ctg tgc ttg cag aaa gaa aga tgt gag att caa ggg ctg      240
 Ala Val Ile Leu Cys Leu Gln Lys Glu Arg Cys Glu Ile Gln Gly Leu
  65                  70                  75                  80

 att att ctc aag ttt ctt cgg aaa ggc aat gga act aga ata gct gaa      288
 Ile Ile Leu Lys Phe Leu Arg Lys Gly Asn Gly Thr Arg Ile Ala Glu
                  85                  90                  95

 aca att ttg aaa aag aaa act aaa gtg gga gga acc att tta tct gat      336
 Thr Ile Leu Lys Lys Lys Thr Lys Val Gly Gly Thr Ile Leu Ser Asp
             100                 105                 110

 ttt aag atg aat aaa gct aga gtt cta gag ata gtg tgg tat ttg tgg      384
 Phe Lys Met Asn Lys Ala Arg Val Leu Glu Ile Val Trp Tyr Leu Trp
         115                 120                 125

 agt aac aga tgc atg aat caa tgg aac aga ata gag gac cca gaa aca      432
 Ser Asn Arg Cys Met Asn Gln Trp Asn Arg Ile Glu Asp Pro Glu Thr
     130                 135                 140

 gat cca caa aca aat ggt gct cta gca att gga cat cca cag acc aaa      480
 Asp Pro Gln Thr Asn Gly Ala Leu Ala Ile Gly His Pro Gln Thr Lys
 145                 150                 155                 160

 caa ata aaa tta aca aat cga ccc caa agc ctc aac cta aac ctc aga      528
 Gln Ile Lys Leu Thr Asn Arg Pro Gln Ser Leu Asn Leu Asn Leu Arg
                 165                 170                 175

 cct gat atg aaa atg aat tca aaa tgg atc gta gac tta aat gta aaa      576
 Pro Asp Met Lys Met Asn Ser Lys Trp Ile Val Asp Leu Asn Val Lys
             180                 185                 190

 tct caa gga tgt gag aac tgc ctg caa aaa ggc agc ttt cag ctt gtt      624
 Ser Gln Gly Cys Glu Asn Cys Leu Gln Lys Gly Ser Phe Gln Leu Val
         195                 200                 205

 ttc act tct ttt ggg agg gaa cat gca gcg aat gtc aat cag gaa tca      672
 Phe Thr Ser Phe Gly Arg Glu His Ala Ala Asn Val Asn Gln Glu Ser
     210                 215                 220

 aaa agc caa aca gag gag gct ttg aac ggt gtc atc ggg ggt cga agt      720
 Lys Ser Gln Thr Glu Glu Ala Leu Asn Gly Val Ile Gly Gly Arg Ser
 225                 230                 235                 240

 gac ttc cag ctg tct gtg cat gac ggg tct aag ccg aca ccc acg atg      768
 Asp Phe Gln Leu Ser Val His Asp Gly Ser Lys Pro Thr Pro Thr Met
                 245                 250                 255

 gag acc cag ccg gtg ttc gat gga gat gac att tat gga aga aag aga      816
 Glu Thr Gln Pro Val Phe Asp Gly Asp Asp Ile Tyr Gly Arg Lys Arg
             260                 265                 270

 tca cca tgg tct ggg aaa agc ttt tgt gaa gag cca gga ctt gag ctg      864
 Ser Pro Trp Ser Gly Lys Ser Phe Cys Glu Glu Pro Gly Leu Glu Leu
         275                 280                 285

 gat ctt gaa agt ggt ggg gag gag tct gag tgt tcc agg cag ggt gct      912
 Asp Leu Glu Ser Gly Gly Glu Glu Ser Glu Cys Ser Arg Gln Gly Ala
     290                 295                 300

 ggc atg gac aag agg gga atg agg tgg caa gac tat gaa caa aag ata      960
 Gly Met Asp Lys Arg Gly Met Arg Trp Gln Asp Tyr Glu Gln Lys Ile
 305                 310                 315                 320

 tat gac ttt gaa cca gca ggc aga att tta cat gac aat caa tta atg     1008
 Tyr Asp Phe Glu Pro Ala Gly Arg Ile Leu His Asp Asn Gln Leu Met
                 325                 330                 335

 agt gtc ctg tca ttg gtc ccc ttt aag ttg acc tgt tca cca gct ctg     1056
 Ser Val Leu Ser Leu Val Pro Phe Lys Leu Thr Cys Ser Pro Ala Leu
             340                 345                 350

 tcc taa                                                             1062
 Ser 






      <210> 513
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 513
  atg gag ctc ggg gtg caa tca ggt agg ctc ttt atg acc ttc ttc acc      48
  Met Glu Leu Gly Val Gln Ser Gly Arg Leu Phe Met Thr Phe Phe Thr
    1               5                  10                  15

 gtt cca gtt cat tac ttc gca ttt cga gca tgt tgt tca tgc tcc agt       96
 Val Pro Val His Tyr Phe Ala Phe Arg Ala Cys Cys Ser Cys Ser Ser
              20                  25                  30

 tct aag aaa tca aga cca ctg agc agc aca gcc aac acc ttc tct ccc      144
 Ser Lys Lys Ser Arg Pro Leu Ser Ser Thr Ala Asn Thr Phe Ser Pro
          35                  40                  45

 aga cat ctt ctg tct cac ctt cgc aat aag cag ccc gcc agc caa gag      192
 Arg His Leu Leu Ser His Leu Arg Asn Lys Gln Pro Ala Ser Gln Glu
      50                  55                  60

 gaa atg gtg gaa act ata act tat atc atc aga aaa ata aag caa gaa      240
 Glu Met Val Glu Thr Ile Thr Tyr Ile Ile Arg Lys Ile Lys Gln Glu
  65                  70                  75                  80

 cag gac act aaa aaa gaa cag tta gag aac aag aag gag ttt ttg gta      288
 Gln Asp Thr Lys Lys Glu Gln Leu Glu Asn Lys Lys Glu Phe Leu Val
                  85                  90                  95

 ctg aaa gat att gca ggc tgt gca tat ctt aaa gga agg tgt tat gct      336
 Leu Lys Asp Ile Ala Gly Cys Ala Tyr Leu Lys Gly Arg Cys Tyr Ala
             100                 105                 110

 gtc ctg tac ttt gca gcc tcc ttt cca cca gat gtg acc act ggt cct      384
 Val Leu Tyr Phe Ala Ala Ser Phe Pro Pro Asp Val Thr Thr Gly Pro
         115                 120                 125

 gct ggt tac tcc tgt ggg ccc tga                                      408
 Ala Gly Tyr Ser Cys Gly Pro 
     130                 135





      <210> 514
      <211> 480
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(480)

      <400> 514
  atg ggg tgg gag tca gtg cta cag gaa cta tgg gcc ctg gtt ttt cta      48
  Met Gly Trp Glu Ser Val Leu Gln Glu Leu Trp Ala Leu Val Phe Leu
    1               5                  10                  15

 atg tgt cag tgt cag tgt gag ggt gac tat acc gat gat gag ggt gaa       96
 Met Cys Gln Cys Gln Cys Glu Gly Asp Tyr Thr Asp Asp Glu Gly Glu
              20                  25                  30

 gag aac caa ata gta aac act act ggg gaa aac ttg aaa tct gtg ctg      144
 Glu Asn Gln Ile Val Asn Thr Thr Gly Glu Asn Leu Lys Ser Val Leu
          35                  40                  45

 atg aat ata aaa caa gga gag gaa aat caa ggg tcc tct ctt ccc cac      192
 Met Asn Ile Lys Gln Gly Glu Glu Asn Gln Gly Ser Ser Leu Pro His
      50                  55                  60

 aga cat gaa cga acc agc tct atg acc aca tct ccc ata acc agc ccc      240
 Arg His Glu Arg Thr Ser Ser Met Thr Thr Ser Pro Ile Thr Ser Pro
  65                  70                  75                  80

 ggc ctg caa agg cag cca cca cag agc ttc tta gtg atg tat cag cgc      288
 Gly Leu Gln Arg Gln Pro Pro Gln Ser Phe Leu Val Met Tyr Gln Arg
                  85                  90                  95

 att cct gat gga cga aat cca gaa aca tct agc tca gaa tct aac aag      336
 Ile Pro Asp Gly Arg Asn Pro Glu Thr Ser Ser Ser Glu Ser Asn Lys
             100                 105                 110

 ctg caa tta agg tgt cca aca ggg ccg aag cct cct ctg aga ctt gga      384
 Leu Gln Leu Arg Cys Pro Thr Gly Pro Lys Pro Pro Leu Arg Leu Gly
         115                 120                 125

 gtt ctc ttc caa gct caa gtc att gtt agc aga att tat gtc ctt gca      432
 Val Leu Phe Gln Ala Gln Val Ile Val Ser Arg Ile Tyr Val Leu Ala
     130                 135                 140

 gct gta aaa cta atg ttg gcc tgt gtc ttc aag gcc aac agg act tag      480
 Ala Val Lys Leu Met Leu Ala Cys Val Phe Lys Ala Asn Arg Thr 
 145                 150                 155





      <210> 515
      <211> 252
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(252)

      <400> 515
  atg aag aga agc aca tcc tgt gga gct gta tat agg atg ctg gtt tca      48
  Met Lys Arg Ser Thr Ser Cys Gly Ala Val Tyr Arg Met Leu Val Ser
    1               5                  10                  15

 atc cgg att ctt cgg tca ctt cta ttc cta agg ggt ccc agg gcc cta       96
 Ile Arg Ile Leu Arg Ser Leu Leu Phe Leu Arg Gly Pro Arg Ala Leu
              20                  25                  30

 ggt gga ggt ttg gga caa ata tgg tat ttg gtc aca agg agc aac agt      144
 Gly Gly Gly Leu Gly Gln Ile Trp Tyr Leu Val Thr Arg Ser Asn Ser
          35                  40                  45

 acg atc tgc tgt atc tgg aat ggg aaa ggc gca cag aat cct gga agg      192
 Thr Ile Cys Cys Ile Trp Asn Gly Lys Gly Ala Gln Asn Pro Gly Arg
      50                  55                  60

 act gaa gac atc aga tgc tat gat aac aag atg gag agt acg agg gca      240
 Thr Glu Asp Ile Arg Cys Tyr Asp Asn Lys Met Glu Ser Thr Arg Ala
  65                  70                  75                  80

 caa gag ctg taa                                                      252
 Gln Glu Leu 






      <210> 516
      <211> 894
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(894)

      <400> 516
  atg cga ccc tcc ggg acg gcc ggg gca gcg ctc ctg gcg ctg ctg gct      48
  Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala
    1               5                  10                  15

 gcg ctc tgc ccg gcg agt cgg gct ctg gag gaa aag aaa gct gcg cag       96
 Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Ala Ala Gln
              20                  25                  30

 gat cgg cgt cag tgg gcg aaa gcc ggg tgc tgg tcc ccg cga tcc tcg      144
 Asp Arg Arg Gln Trp Ala Lys Ala Gly Cys Trp Ser Pro Arg Ser Ser
          35                  40                  45

 ttc ccc agt gtg gag tcg cag cct cga cct ggg agc tgg gag aac tcg      192
 Phe Pro Ser Val Glu Ser Gln Pro Arg Pro Gly Ser Trp Glu Asn Ser
      50                  55                  60

 tct acc acc acc tgc ggc tcc cgg gga ggg gtg gtg ctg gcg gcg gtt      240
 Ser Thr Thr Thr Cys Gly Ser Arg Gly Gly Val Val Leu Ala Ala Val
  65                  70                  75                  80

 agt ttc ctc gtt ggc aaa agg cag ggt ctg gct cga cag agc agg agc      288
 Ser Phe Leu Val Gly Lys Arg Gln Gly Leu Ala Arg Gln Ser Arg Ser
                  85                  90                  95

 atc gcc atc ttg gac aag ccc ctc att cta aag ttc acc tta ata aaa      336
 Ile Ala Ile Leu Asp Lys Pro Leu Ile Leu Lys Phe Thr Leu Ile Lys
             100                 105                 110

 aac tgc cta aat tca aac tgc atc agc cta atg gct aag tca aca aaa      384
 Asn Cys Leu Asn Ser Asn Cys Ile Ser Leu Met Ala Lys Ser Thr Lys
         115                 120                 125

 atc tac ctg gcc aag gca gaa cag aaa gtt cag caa ttt gat gaa gtg      432
 Ile Tyr Leu Ala Lys Ala Glu Gln Lys Val Gln Gln Phe Asp Glu Val
     130                 135                 140

 gga caa cat gaa gaa tca gtt ctc tta cta tac act gat ggt gac gca      480
 Gly Gln His Glu Glu Ser Val Leu Leu Leu Tyr Thr Asp Gly Asp Ala
 145                 150                 155                 160

 gaa att cag aat tcc ccg cat gtg tcc cgg ttt gaa agc cac tgt gct      528
 Glu Ile Gln Asn Ser Pro His Val Ser Arg Phe Glu Ser His Cys Ala
                 165                 170                 175

 ttg ctg tgg att agg atc aga cag ttg agt ctt gtt cca aca agg aaa      576
 Leu Leu Trp Ile Arg Ile Arg Gln Leu Ser Leu Val Pro Thr Arg Lys
             180                 185                 190

 gtt gct tat tgg aaa gtt ttg ctg cag gga gcc ttg agt tct gca tca      624
 Val Ala Tyr Trp Lys Val Leu Leu Gln Gly Ala Leu Ser Ser Ala Ser
         195                 200                 205

 ggc ttg gaa gtg ggc tct gtg gag aca aca cac agc atc agc cag act      672
 Gly Leu Glu Val Gly Ser Val Glu Thr Thr His Ser Ile Ser Gln Thr
     210                 215                 220

 aac aca aag gac gtc atg ggc atg gac gta aat act ggt gtc aac act      720
 Asn Thr Lys Asp Val Met Gly Met Asp Val Asn Thr Gly Val Asn Thr
 225                 230                 235                 240

 agg tct gca cct cga gag gag tgg agc aaa agg atg gag tgg cag atg      768
 Arg Ser Ala Pro Arg Glu Glu Trp Ser Lys Arg Met Glu Trp Gln Met
                 245                 250                 255

 aag ctg tgg gac ttg agt aag ctc ctg aag cag ctg cac ctg cat ttt      816
 Lys Leu Trp Asp Leu Ser Lys Leu Leu Lys Gln Leu His Leu His Phe
             260                 265                 270

 ctg gtg ggc acc atg gag ctg tca gca gtg ctt tcc tca gag ggc tgc      864
 Leu Val Gly Thr Met Glu Leu Ser Ala Val Leu Ser Ser Glu Gly Cys
         275                 280                 285

 ggg ctg gat gag gtt tgc tgg tgc atg tga                              894
 Gly Leu Asp Glu Val Cys Trp Cys Met 
     290                 295





      <210> 517
      <211> 513
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(513)

      <400> 517
  atg gcc ctc ctc tcc act tct gca gct cca gtg acg ctg ttc cta ctc      48
  Met Ala Leu Leu Ser Thr Ser Ala Ala Pro Val Thr Leu Phe Leu Leu
    1               5                  10                  15

 att gtc aca ctg gaa tgg ttg cag gat gaa cac gat cct ctg gaa atg       96
 Ile Val Thr Leu Glu Trp Leu Gln Asp Glu His Asp Pro Leu Glu Met
              20                  25                  30

 gag aca tct tct gaa gat gcc ctt ctc agg tct ctc att ggc aga ttt      144
 Glu Thr Ser Ser Glu Asp Ala Leu Leu Arg Ser Leu Ile Gly Arg Phe
          35                  40                  45

 gac cat cac caa agt act gag gtc tgg gaa agt agg aac ttg tcg ttt      192
 Asp His His Gln Ser Thr Glu Val Trp Glu Ser Arg Asn Leu Ser Phe
      50                  55                  60

 cag gaa tca gtg gct ttt gag gac gtg gct gtg tac ttc act acg aag      240
 Gln Glu Ser Val Ala Phe Glu Asp Val Ala Val Tyr Phe Thr Thr Lys
  65                  70                  75                  80

 gaa tgg gcc atc atg gtg cct gcc gag agg gcc ttg tac agg gat gtg      288
 Glu Trp Ala Ile Met Val Pro Ala Glu Arg Ala Leu Tyr Arg Asp Val
                  85                  90                  95

 atg ctg gag aac tat gag gct gtg gcc ttt gta gtg ctg aaa gat atc      336
 Met Leu Glu Asn Tyr Glu Ala Val Ala Phe Val Val Leu Lys Asp Ile
             100                 105                 110

 cta aga tcc tgc tcc cac aca tat acg ggc tgt agc cag cta cag tct      384
 Leu Arg Ser Cys Ser His Thr Tyr Thr Gly Cys Ser Gln Leu Gln Ser
         115                 120                 125

 ttg ttt atc ttc cca tgc tca gga ttg gaa gtg gct gaa gat ctt gct      432
 Leu Phe Ile Phe Pro Cys Ser Gly Leu Glu Val Ala Glu Asp Leu Ala
     130                 135                 140

 cct gag cct ctc tgg tca ata tca ggc cac aag ggt ggg gag tta gag      480
 Pro Glu Pro Leu Trp Ser Ile Ser Gly His Lys Gly Gly Glu Leu Glu
 145                 150                 155                 160

 agt tgg atg tct gtg ctc aac tca tca tct taa                          513
 Ser Trp Met Ser Val Leu Asn Ser Ser Ser 
                 165                 170





      <210> 518
      <211> 300
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(300)

      <400> 518
  atg ctg ctg tgc atg acc cac ttt atg gct aga tgg gtc aga aag cac      48
  Met Leu Leu Cys Met Thr His Phe Met Ala Arg Trp Val Arg Lys His
    1               5                  10                  15

 cca gtt cat gat aag caa ttc agg ttc cat gca gca ttg gat ctg ctg       96
 Pro Val His Asp Lys Gln Phe Arg Phe His Ala Ala Leu Asp Leu Leu
              20                  25                  30

 ggt cat atg gcc caa gtg gca gag cag ttt gca cgg cag cct gga cct      144
 Gly His Met Ala Gln Val Ala Glu Gln Phe Ala Arg Gln Pro Gly Pro
          35                  40                  45

 gtt gca gag cct tct ctt att ctg gac ccc act caa aac tgg cag cct      192
 Val Ala Glu Pro Ser Leu Ile Leu Asp Pro Thr Gln Asn Trp Gln Pro
      50                  55                  60

 ttt ggg tca ctg gat aaa tgg gcc aga gta aca cac cca aat gaa gaa      240
 Phe Gly Ser Leu Asp Lys Trp Ala Arg Val Thr His Pro Asn Glu Glu
  65                  70                  75                  80

 tgt gtt gcc tcc aaa atc caa aca agc cca cta ggc att gtg cct cct      288
 Cys Val Ala Ser Lys Ile Gln Thr Ser Pro Leu Gly Ile Val Pro Pro
                  85                  90                  95

 tct tgg ttg tag                                                      300
 Ser Trp Leu 






      <210> 519
      <211> 429
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(429)

      <400> 519
  atg gca tac ctg agt aaa gta att gat gta gtg gca aag act tgg cct      48
  Met Ala Tyr Leu Ser Lys Val Ile Asp Val Val Ala Lys Thr Trp Pro
    1               5                  10                  15

 cat tgt tta tgg gta gtg gtg tca gta gca gtc tta gta tct gaa gca       96
 His Cys Leu Trp Val Val Val Ser Val Ala Val Leu Val Ser Glu Ala
              20                  25                  30

 gtt aaa ata ata cag gga aga gat ctt act gtg tgg aca tct cat gat      144
 Val Lys Ile Ile Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp
          35                  40                  45

 gtg gat ggc ata ctc act gct aaa gga gac ttg tgg ctg cca gac aac      192
 Val Asp Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp Leu Pro Asp Asn
      50                  55                  60

 tgt tta ctt aaa tat cag cct cta tta ctt gaa ggg cca gtg cta att      240
 Cys Leu Leu Lys Tyr Gln Pro Leu Leu Leu Glu Gly Pro Val Leu Ile
  65                  70                  75                  80

 gaa gcc gta aaa cta caa att gtt ctt caa atg gag ccc cag atg cag      288
 Glu Ala Val Lys Leu Gln Ile Val Leu Gln Met Glu Pro Gln Met Gln
                  85                  90                  95

 tcc atg act aag ata tac cgt gga ccc ctg gac cag cct gct agc cca      336
 Ser Met Thr Lys Ile Tyr Arg Gly Pro Leu Asp Gln Pro Ala Ser Pro
             100                 105                 110

 tgt tcc aat gtt aat gac atc gaa ggc aca cct ccc aag gaa atc tca      384
 Cys Ser Asn Val Asn Asp Ile Glu Gly Thr Pro Pro Lys Glu Ile Ser
         115                 120                 125

 act gca tca ccc cta cta tgc ccc aat tca gcc gga agc agt tag          429
 Thr Ala Ser Pro Leu Leu Cys Pro Asn Ser Ala Gly Ser Ser 
     130                 135                 140





      <210> 520
      <211> 366
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(366)

      <400> 520
  atg ctg tgg ctg gcc ctc tcc tct gcc gca gcc gca cag ccc agc ggc      48
  Met Leu Trp Leu Ala Leu Ser Ser Ala Ala Ala Ala Gln Pro Ser Gly
    1               5                  10                  15

 cgc ttc ttt caa ggc aat tcc agc agc tgg ctg gtg aat cca cat gat       96
 Arg Phe Phe Gln Gly Asn Ser Ser Ser Trp Leu Val Asn Pro His Asp
              20                  25                  30

 gag ttt cca aat ctc tcc act gag gag gac atg aaa gca gaa aca ctg      144
 Glu Phe Pro Asn Leu Ser Thr Glu Glu Asp Met Lys Ala Glu Thr Leu
          35                  40                  45

 gga ata aat aac ata aat aca tcc cct cca gga aag gca gag aag gtg      192
 Gly Ile Asn Asn Ile Asn Thr Ser Pro Pro Gly Lys Ala Glu Lys Val
      50                  55                  60

 cag gag att atg ctg ctg gat gaa gga gaa cat gca gga aac ctg att      240
 Gln Glu Ile Met Leu Leu Asp Glu Gly Glu His Ala Gly Asn Leu Ile
  65                  70                  75                  80

 gaa tct gct gac ttt ggc cat gac gac aat ccc acc atc acc gcc aca      288
 Glu Ser Ala Asp Phe Gly His Asp Asp Asn Pro Thr Ile Thr Ala Thr
                  85                  90                  95

 gga gat caa ttg tcg cgt gtg ctg tgc ata gga gag ggc ctg gac tct      336
 Gly Asp Gln Leu Ser Arg Val Leu Cys Ile Gly Glu Gly Leu Asp Ser
             100                 105                 110

 gtc gct gtg aaa gaa acc aag ggt tat tga                              366
 Val Ala Val Lys Glu Thr Lys Gly Tyr 
         115                 120





      <210> 521
      <211> 531
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(531)

      <400> 521
  atg att gta gta ggt gtg atg ctt gga agt tcg tat gtg tca gtg agt      48
  Met Ile Val Val Gly Val Met Leu Gly Ser Ser Tyr Val Ser Val Ser
    1               5                  10                  15

 ttt cta agt cat tgt gag tac ttt att gct aat aaa att ggt tac aaa       96
 Phe Leu Ser His Cys Glu Tyr Phe Ile Ala Asn Lys Ile Gly Tyr Lys
              20                  25                  30

 aat gtg tat agt ttc ttt gcc ttg aac act ctc agc ttc tcc aga ctc      144
 Asn Val Tyr Ser Phe Phe Ala Leu Asn Thr Leu Ser Phe Ser Arg Leu
          35                  40                  45

 tct ctc ttc cat ccc tct ccc aga aaa ggc aga ctt gtg cag ctc ctg      192
 Ser Leu Phe His Pro Ser Pro Arg Lys Gly Arg Leu Val Gln Leu Leu
      50                  55                  60

 aac aca tac tta cca agg gta gag cca gca tat gtg aag act tct gat      240
 Asn Thr Tyr Leu Pro Arg Val Glu Pro Ala Tyr Val Lys Thr Ser Asp
  65                  70                  75                  80

 gag aca aaa att gct aag gga agt ctt aga ggt tta aag ctg gaa gaa      288
 Glu Thr Lys Ile Ala Lys Gly Ser Leu Arg Gly Leu Lys Leu Glu Glu
                  85                  90                  95

 ata aag ctg tgc aag cat tgt ttt ccc aga aca agc cag aag gag tat      336
 Ile Lys Leu Cys Lys His Cys Phe Pro Arg Thr Ser Gln Lys Glu Tyr
             100                 105                 110

 gtt atg cct cat gac aac aag ctc tta caa tcc acc tca aac aca acc      384
 Val Met Pro His Asp Asn Lys Leu Leu Gln Ser Thr Ser Asn Thr Thr
         115                 120                 125

 aaa ata aac cta atg agt tgc tat cat gta aga gaa cat tac aaa atc      432
 Lys Ile Asn Leu Met Ser Cys Tyr His Val Arg Glu His Tyr Lys Ile
     130                 135                 140

 ata gag aac aac aac aac gca gtc atc ttt acc atc tac cta cca ttc      480
 Ile Glu Asn Asn Asn Asn Ala Val Ile Phe Thr Ile Tyr Leu Pro Phe
 145                 150                 155                 160

 att aat tta gat gat gac cat ctc tta ttc aat ttt gta cag tca acc      528
 Ile Asn Leu Asp Asp Asp His Leu Leu Phe Asn Phe Val Gln Ser Thr
                 165                 170                 175

 taa                                                                  531
 






      <210> 522
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 522
  atg gct cct ctg tat ttc ctc aca ttt gca gct ctg ctc cct ctt tgt      48
  Met Ala Pro Leu Tyr Phe Leu Thr Phe Ala Ala Leu Leu Pro Leu Cys
    1               5                  10                  15

 gct ctg aga ttg agt acg cat ccc cag cgc aag acg cga cat ctc ttc       96
 Ala Leu Arg Leu Ser Thr His Pro Gln Arg Lys Thr Arg His Leu Phe
              20                  25                  30

 ttc gtt gag cgg atc ggc ttt cgg atc cag cgc cct gtc cag caa cgc      144
 Phe Val Glu Arg Ile Gly Phe Arg Ile Gln Arg Pro Val Gln Gln Arg
          35                  40                  45

 cgg agc ctg tgc cgt ggc ctg ctg cca gat ttt cac ctg ctg ata att      192
 Arg Ser Leu Cys Arg Gly Leu Leu Pro Asp Phe His Leu Leu Ile Ile
      50                  55                  60

 gcc agt ctg ata aac aac ata tcc ggc acg ctt acc ttc cgg cac gct      240
 Ala Ser Leu Ile Asn Asn Ile Ser Gly Thr Leu Thr Phe Arg His Ala
  65                  70                  75                  80

 ttg ttc agg aaa cgc ttc cgg cac cac gcg tac ccg acg ccg cga gcg      288
 Leu Phe Arg Lys Arg Phe Arg His His Ala Tyr Pro Thr Pro Arg Ala
                  85                  90                  95

 ggc gta tat gac cca acc gcc aat gcc aat agc cac tac tgg cag cac      336
 Gly Val Tyr Asp Pro Thr Ala Asn Ala Asn Ser His Tyr Trp Gln His
             100                 105                 110

 cca cag cag cac ggc ttg gga ggg agt gaa aaa att aag gac tta gtc      384
 Pro Gln Gln His Gly Leu Gly Gly Ser Glu Lys Ile Lys Asp Leu Val
         115                 120                 125

 gat ccc cag cac agc atg gct gcc tga                                  411
 Asp Pro Gln His Ser Met Ala Ala 
     130                 135





      <210> 523
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 523
  atg agt ttt gat tgg atg gca tac att gtg agt cat ata cta ttg gtt      48
  Met Ser Phe Asp Trp Met Ala Tyr Ile Val Ser His Ile Leu Leu Val
    1               5                  10                  15

 gtt gga ttt tat tac atg ttt tta aat aat gat gtg ttc att ttg gtg       96
 Val Gly Phe Tyr Tyr Met Phe Leu Asn Asn Asp Val Phe Ile Leu Val
              20                  25                  30

 tgc agg atc atc ttc tcc acg ccc ctg gcc gtc att gcc tac ttc ctc      144
 Cys Arg Ile Ile Phe Ser Thr Pro Leu Ala Val Ile Ala Tyr Phe Leu
          35                  40                  45

 atc tgg ttc gtg ccc gac ttc cca cac ggc cag acc tat tgg tac ctg      192
 Ile Trp Phe Val Pro Asp Phe Pro His Gly Gln Thr Tyr Trp Tyr Leu
      50                  55                  60

 ctt ttc tat tgc ctc ttt gaa aca atg gtc acg tgt ttc cat gtt ccc      240
 Leu Phe Tyr Cys Leu Phe Glu Thr Met Val Thr Cys Phe His Val Pro
  65                  70                  75                  80

 tac tcg gct ctc acc atg ttc atc agc acc gag cag act gag cgg gat      288
 Tyr Ser Ala Leu Thr Met Phe Ile Ser Thr Glu Gln Thr Glu Arg Asp
                  85                  90                  95

 tct gcc acc gcc tat cta ttt att cgc gat aag ctc atg gga gcg gcg      336
 Ser Ala Thr Ala Tyr Leu Phe Ile Arg Asp Lys Leu Met Gly Ala Ala
             100                 105                 110

 ggt aac cgt cgc aca gga aag gac aga gaa agc gcg gta tct ggg aaa      384
 Gly Asn Arg Arg Thr Gly Lys Asp Arg Glu Ser Ala Val Ser Gly Lys
         115                 120                 125

 gtg acg gac aga acg gtc agg acc tgg att ggg gag gcg gtt gcc gcc      432
 Val Thr Asp Arg Thr Val Arg Thr Trp Ile Gly Glu Ala Val Ala Ala
     130                 135                 140

 gct gct gct gac ggt gtg acg ttc tct gtt ccg gtc aca cca cat acg      480
 Ala Ala Ala Asp Gly Val Thr Phe Ser Val Pro Val Thr Pro His Thr
 145                 150                 155                 160

 ttc cgc cat tcc tat gcg atg cac atg ctg tat gcc ggt ata ccg ctg      528
 Phe Arg His Ser Tyr Ala Met His Met Leu Tyr Ala Gly Ile Pro Leu
                 165                 170                 175

 aaa gtt ctg caa agc ctg atg gga cat aag tcc atc agt tca acg gaa      576
 Lys Val Leu Gln Ser Leu Met Gly His Lys Ser Ile Ser Ser Thr Glu
             180                 185                 190

 gtc tac acg aag gtt ttt gcg ctg gat gtg gct gcc cgg cac cgg gtg      624
 Val Tyr Thr Lys Val Phe Ala Leu Asp Val Ala Ala Arg His Arg Val
         195                 200                 205

 cag ttt gcg atg ccg gag tct gat gcg gtt gcg atg ctg aaa caa tta      672
 Gln Phe Ala Met Pro Glu Ser Asp Ala Val Ala Met Leu Lys Gln Leu
     210                 215                 220

 tcc tga                                                              678
 Ser 
 225





      <210> 524
      <211> 429
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(429)

      <400> 524
  atg ttt ccc gct cac cag cag atg gcg gtg ttg gat gcg gta ctg gcc      48
  Met Phe Pro Ala His Gln Gln Met Ala Val Leu Asp Ala Val Leu Ala
    1               5                  10                  15

 ttc gac ctg cgg ttc ctg gtt acg cgg aaa ttt tgg aga ccc tgg agc       96
 Phe Asp Leu Arg Phe Leu Val Thr Arg Lys Phe Trp Arg Pro Trp Ser
              20                  25                  30

 cgc ggt ctg aat cac atc acc tcc gag cag gag gcc cgt gtt gag aac      144
 Arg Gly Leu Asn His Ile Thr Ser Glu Gln Glu Ala Arg Val Glu Asn
          35                  40                  45

 tgt gtt cta ccg tct tct ttt acg gtg ttt aac ggg tgg aat aaa tgt      192
 Cys Val Leu Pro Ser Ser Phe Thr Val Phe Asn Gly Trp Asn Lys Cys
      50                  55                  60

 gtc aag gtt gga agc ctg gtt ttg ggc aaa tta cat tct gga tct gga      240
 Val Lys Val Gly Ser Leu Val Leu Gly Lys Leu His Ser Gly Ser Gly
  65                  70                  75                  80

 aat cac tgt gac aat tct tca cag agc tct cag gtg tgg gga ttg acg      288
 Asn His Cys Asp Asn Ser Ser Gln Ser Ser Gln Val Trp Gly Leu Thr
                  85                  90                  95

 acc cag gct cca cga ccc att ccc gcc ctc cgg agc tct cag gga gca      336
 Thr Gln Ala Pro Arg Pro Ile Pro Ala Leu Arg Ser Ser Gln Gly Ala
             100                 105                 110

 ggc ctg gat gat gaa ttc atc agc ccg cag ctg tgt gca ttc aac tgt      384
 Gly Leu Asp Asp Glu Phe Ile Ser Pro Gln Leu Cys Ala Phe Asn Cys
         115                 120                 125

 tca gtt tct gct gct gaa gcg ttt gga cgc atc ttt agg gcg tga          429
 Ser Val Ser Ala Ala Glu Ala Phe Gly Arg Ile Phe Arg Ala 
     130                 135                 140





      <210> 525
      <211> 1062
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1062)

      <400> 525
  atg cct gtc cga aaa atc att cgt ata aaa tta gtc tac caa atc ctc      48
  Met Pro Val Arg Lys Ile Ile Arg Ile Lys Leu Val Tyr Gln Ile Leu
    1               5                  10                  15

 acc gca ttt ttc acg cat atc cgc gac cat agc ggc atc ttt gcg gat       96
 Thr Ala Phe Phe Thr His Ile Arg Asp His Ser Gly Ile Phe Ala Asp
              20                  25                  30

 ccc cgc atc gcc atc atg tgg ccc cca gtg cgt cgg cat ttt gcc acc      144
 Pro Arg Ile Ala Ile Met Trp Pro Pro Val Arg Arg His Phe Ala Thr
          35                  40                  45

 gat aaa gcc cat ctc ttt tgc cag atc cgg acg cgc acc tgt ggc ttt      192
 Asp Lys Ala His Leu Phe Cys Gln Ile Arg Thr Arg Thr Cys Gly Phe
      50                  55                  60

 ata aac cgg aag ccc gac cac ttt gcc gaa cag atc cca cag agc cag      240
 Ile Asn Arg Lys Pro Asp His Phe Ala Glu Gln Ile Pro Gln Ser Gln
  65                  70                  75                  80

 atc gac aca aga aat cgt att cat cac cag gcc acc aga gcc gga gta      288
 Ile Asp Thr Arg Asn Arg Ile His His Gln Ala Thr Arg Ala Gly Val
                  85                  90                  95

 ata cag ggt ggc act gag cat ttg atc gtg gat cag ttt gat atc act      336
 Ile Gln Gly Gly Thr Glu His Leu Ile Val Asp Gln Phe Asp Ile Thr
             100                 105                 110

 gac aca ttt acc ctc aat gaa acg gtt aag atg ttt ttc gac aat aaa      384
 Asp Thr Phe Thr Leu Asn Glu Thr Val Lys Met Phe Phe Asp Asn Lys
         115                 120                 125

 aca gcc cat ttc acc ggc tgt cga aac ggc gaa tcc ggt ctg gcc gtt      432
 Thr Ala His Phe Thr Gly Cys Arg Asn Gly Glu Ser Gly Leu Ala Val
     130                 135                 140

 ttc tgc ttc gac ttc aac aac caa cgt gcg cgt ccg gat ctg gca aaa      480
 Phe Cys Phe Asp Phe Asn Asn Gln Arg Ala Arg Pro Asp Leu Ala Lys
 145                 150                 155                 160

 gag atg ggc ttt atc ggt ggc aaa atg ccg acg cac tgg ggg cca cat      528
 Glu Met Gly Phe Ile Gly Gly Lys Met Pro Thr His Trp Gly Pro His
                 165                 170                 175

 gat ggc gat gcg ggg atc cgc aaa gat gcc gct atg gtc gcg gat atg      576
 Asp Gly Asp Ala Gly Ile Arg Lys Asp Ala Ala Met Val Ala Asp Met
             180                 185                 190

 cgt gaa aaa tgc ggt gag gat ttc tgg tta atg ctc gac tgc tgg atg      624
 Arg Glu Lys Cys Gly Glu Asp Phe Trp Leu Met Leu Asp Cys Trp Met
         195                 200                 205

 agt cag gac gtg aac tat gcg acc aaa ctg gcc cac gct tgc gcg ccc      672
 Ser Gln Asp Val Asn Tyr Ala Thr Lys Leu Ala His Ala Cys Ala Pro
     210                 215                 220

 tat aac ctg aaa tgg atc gaa gag tgc ctg ccg cca cag cag tat gaa      720
 Tyr Asn Leu Lys Trp Ile Glu Glu Cys Leu Pro Pro Gln Gln Tyr Glu
 225                 230                 235                 240

 agt tat cgc gaa ctg aaa cgc aac gcg cca gtc gga atg atg gtc acc      768
 Ser Tyr Arg Glu Leu Lys Arg Asn Ala Pro Val Gly Met Met Val Thr
                 245                 250                 255

 agc ggt gag cac cac ggc aca ctg caa tct ttt cgt acg ctt tca gaa      816
 Ser Gly Glu His His Gly Thr Leu Gln Ser Phe Arg Thr Leu Ser Glu
             260                 265                 270

 acc ggt atc gac att atg cag ccg gat gtt ggc tgg tgc ggt ggt tta      864
 Thr Gly Ile Asp Ile Met Gln Pro Asp Val Gly Trp Cys Gly Gly Leu
         275                 280                 285

 acc acg ctg gtg gaa att gcc gca atc gcc aaa tcc agg ggg caa ctg      912
 Thr Thr Leu Val Glu Ile Ala Ala Ile Ala Lys Ser Arg Gly Gln Leu
     290                 295                 300

 gtg gtg ccg cac ggt tcg tct gtt tac tct cac cat gcg gtg atc acc      960
 Val Val Pro His Gly Ser Ser Val Tyr Ser His His Ala Val Ile Thr
 305                 310                 315                 320

 ttc acc aat acg cca ttc aaa gaa ttc ctg atg acc agc ccg gat tgt     1008
 Phe Thr Asn Thr Pro Phe Lys Glu Phe Leu Met Thr Ser Pro Asp Cys
                 325                 330                 335

 tca acg atg cgt ccg cag ttt gac ccg agg gga tac tct aga gtc gga     1056
 Ser Thr Met Arg Pro Gln Phe Asp Pro Arg Gly Tyr Ser Arg Val Gly
             340                 345                 350

 cct tga                                                             1062
 Pro 






      <210> 526
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 526
  atg cct aat ttc ttt atc gat cgc ccg att ttt gcg tgg gtg atc gcc      48
  Met Pro Asn Phe Phe Ile Asp Arg Pro Ile Phe Ala Trp Val Ile Ala
    1               5                  10                  15

 att atc atc atg ttg gca ggg ggg ctg gcg atc ctc aaa ctg ccg gtg       96
 Ile Ile Ile Met Leu Ala Gly Gly Leu Ala Ile Leu Lys Leu Pro Val
              20                  25                  30

 gcg caa tat cct acg att gca ccg ccg gca gta acg atc tcc gcc tcc      144
 Ala Gln Tyr Pro Thr Ile Ala Pro Pro Ala Val Thr Ile Ser Ala Ser
          35                  40                  45

 tac ccc ggc gct gat gcg aaa aca gtg cag gac acg gtg aca cag gtt      192
 Tyr Pro Gly Ala Asp Ala Lys Thr Val Gln Asp Thr Val Thr Gln Val
      50                  55                  60

 atc gaa cag aat atg aac ggt atc gat aac ctg atg tac atg tcc tct      240
 Ile Glu Gln Asn Met Asn Gly Ile Asp Asn Leu Met Tyr Met Ser Ser
  65                  70                  75                  80

 aac agt gac tcc acg ggt acc gtg cag atc acc ctg acc ttt gag tct      288
 Asn Ser Asp Ser Thr Gly Thr Val Gln Ile Thr Leu Thr Phe Glu Ser
                  85                  90                  95

 ggt act gat gcg gat atc gcg cag gtt cag gtg cag aac aaa ctg cag      336
 Gly Thr Asp Ala Asp Ile Ala Gln Val Gln Val Gln Asn Lys Leu Gln
             100                 105                 110

 ctg gcg ata aaa tta aat gcc gca aga agt tca gca gca agg tag          381
 Leu Ala Ile Lys Leu Asn Ala Ala Arg Ser Ser Ala Ala Arg 
         115                 120                 125





      <210> 527
      <211> 606
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(606)

      <400> 527
  atg gtg ttg gca tac ctg cat cag gcc gcg gca gag cta gct ctc ctt      48
  Met Val Leu Ala Tyr Leu His Gln Ala Ala Ala Glu Leu Ala Leu Leu
    1               5                  10                  15

 cta gac tgt gaa gtc ata gaa gcc aac aag tta act ttt tgc ata agc       96
 Leu Asp Cys Glu Val Ile Glu Ala Asn Lys Leu Thr Phe Cys Ile Ser
              20                  25                  30

 cag ttt gga ttc tgg gag aat agg gcc ttc tgc aat cac aga cac atg      144
 Gln Phe Gly Phe Trp Glu Asn Arg Ala Phe Cys Asn His Arg His Met
          35                  40                  45

 tca ctt ggc aac agg ggc ccc cag gga gtt gac ggg aag atg cct cct      192
 Ser Leu Gly Asn Arg Gly Pro Gln Gly Val Asp Gly Lys Met Pro Pro
      50                  55                  60

 aag ctt gga tct gcg gcc ttt gtg ggt agc atc att gga ttg ttt act      240
 Lys Leu Gly Ser Ala Ala Phe Val Gly Ser Ile Ile Gly Leu Phe Thr
  65                  70                  75                  80

 cag agc cca ggg tcc agg aag aag gcc aca aag gcc tct tca gtg gtg      288
 Gln Ser Pro Gly Ser Arg Lys Lys Ala Thr Lys Ala Ser Ser Val Val
                  85                  90                  95

 gtg gca cag tgc cca gca gtc ccg tgg gca cct acg aca gcc gca gga      336
 Val Ala Gln Cys Pro Ala Val Pro Trp Ala Pro Thr Thr Ala Ala Gly
             100                 105                 110

 gtt tcc cat gct tcc tgc cgt gtg gtt cag aga gag tta ttt agg tcc      384
 Val Ser His Ala Ser Cys Arg Val Val Gln Arg Glu Leu Phe Arg Ser
         115                 120                 125

 ctc gac tat atg gtc acc gtc gac agc gac aca ctt gca tcg gat gca      432
 Leu Asp Tyr Met Val Thr Val Asp Ser Asp Thr Leu Ala Ser Asp Ala
     130                 135                 140

 gcc cgg tta acg tgc cgg cac gcg ctg ggt aac cag tct cac gct gat      480
 Ala Arg Leu Thr Cys Arg His Ala Leu Gly Asn Gln Ser His Ala Asp
 145                 150                 155                 160

 agt ctg atc gac aat aca agt ggg acc gtg ggt cat acc gat aat cag      528
 Ser Leu Ile Asp Asn Thr Ser Gly Thr Val Gly His Thr Asp Asn Gln
                 165                 170                 175

 acc gac aac acg agt ggg atc gtg ttc cag act aat agt cag acc gac      576
 Thr Asp Asn Thr Ser Gly Ile Val Phe Gln Thr Asn Ser Gln Thr Asp
             180                 185                 190

 gat acg agt ggg acc gtg gtt cga atc taa                              606
 Asp Thr Ser Gly Thr Val Val Arg Ile 
         195                 200





      <210> 528
      <211> 420
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(420)

      <400> 528
  atg gtg atg act ttc ttg ggt ttt ctt ttt gcc tca tcc act caa gat      48
  Met Val Met Thr Phe Leu Gly Phe Leu Phe Ala Ser Ser Thr Gln Asp
    1               5                  10                  15

 ttg gag ctg aag gaa cca gca act gta aaa cac caa tgg gaa cac aga       96
 Leu Glu Leu Lys Glu Pro Ala Thr Val Lys His Gln Trp Glu His Arg
              20                  25                  30

 tac aca cac aca cca atc ccc aac aga aat tcc ctc ttg cta agt aaa      144
 Tyr Thr His Thr Pro Ile Pro Asn Arg Asn Ser Leu Leu Leu Ser Lys
          35                  40                  45

 ggc cca aga aaa gca cag cag aag aag aca gaa aaa tct tgg aga gta      192
 Gly Pro Arg Lys Ala Gln Gln Lys Lys Thr Glu Lys Ser Trp Arg Val
      50                  55                  60

 ggt gca cta cta cag tca aat acc acc cca acc cta cca gca agg gcc      240
 Gly Ala Leu Leu Gln Ser Asn Thr Thr Pro Thr Leu Pro Ala Arg Ala
  65                  70                  75                  80

 aag aga caa gaa cgg agt aac ctc ggt gtg cgg ttg tat gcc tgc tgt      288
 Lys Arg Gln Glu Arg Ser Asn Leu Gly Val Arg Leu Tyr Ala Cys Cys
                  85                  90                  95

 gga ttg ctg ctg tgt cct gct tat cca caa cat ttt gcg cac ggt tat      336
 Gly Leu Leu Leu Cys Pro Ala Tyr Pro Gln His Phe Ala His Gly Tyr
             100                 105                 110

 gtg gac aaa ata cct ggt tac cca ggc cgt gcc ggc acg tta acc ggg      384
 Val Asp Lys Ile Pro Gly Tyr Pro Gly Arg Ala Gly Thr Leu Thr Gly
         115                 120                 125

 ttg cat ccg atg caa gtg tgt cgc tgt cga cgg tga                      420
 Leu His Pro Met Gln Val Cys Arg Cys Arg Arg 
     130                 135





      <210> 529
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 529
  atg acg ctc tct ttc ttc tgg cct cta cca ctg gtg ctg ctg gtt ctg      48
  Met Thr Leu Ser Phe Phe Trp Pro Leu Pro Leu Val Leu Leu Val Leu
    1               5                  10                  15

 ggt gcg ctg tta ctg gcg att atc tgg acg cgc ctg gaa gag tac cgt       96
 Gly Ala Leu Leu Leu Ala Ile Ile Trp Thr Arg Leu Glu Glu Tyr Arg
              20                  25                  30

 tgg cct atc tgc acg ttt atc ggc atg acg ctg gtg atg aac gcc aac      144
 Trp Pro Ile Cys Thr Phe Ile Gly Met Thr Leu Val Met Asn Ala Asn
          35                  40                  45

 gac tgt tgc tgc gac ggc gca tgt tcc agc acg cca act ctc tct gaa      192
 Asp Cys Cys Cys Asp Gly Ala Cys Ser Ser Thr Pro Thr Leu Ser Glu
      50                  55                  60

 aac gtc tcc ggc acc cgc tat agc tgg aaa gtc agc ggc atg gac tgc      240
 Asn Val Ser Gly Thr Arg Tyr Ser Trp Lys Val Ser Gly Met Asp Cys
  65                  70                  75                  80

 gcc gcc tgt gcg cgc aag gta gaa aat gcc gtg cgc cag ctt gca ggc      288
 Ala Ala Cys Ala Arg Lys Val Glu Asn Ala Val Arg Gln Leu Ala Gly
                  85                  90                  95

 gtg aat cag gtg cag gtg ttg ttc gcc acc gaa aaa ctg gtg gtc gat      336
 Val Asn Gln Val Gln Val Leu Phe Ala Thr Glu Lys Leu Val Val Asp
             100                 105                 110

 gcc gac aat gac att cgt gca cag ttg aat ctg cgc tgc aaa aag cag      384
 Ala Asp Asn Asp Ile Arg Ala Gln Leu Asn Leu Arg Cys Lys Lys Gln
         115                 120                 125

 gct att ccc tgc gcg atg aac agg ccg ccg aag aac cgc aag cat cac      432
 Ala Ile Pro Cys Ala Met Asn Arg Pro Pro Lys Asn Arg Lys His His
     130                 135                 140

 gcc tga                                                              438
 Ala 
 145





      <210> 530
      <211> 576
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(576)

      <400> 530
  atg aag gca tcc tgg gtg cac ctg gcg ctc tgc ctg gcc cac agc gca      48
  Met Lys Ala Ser Trp Val His Leu Ala Leu Cys Leu Ala His Ser Ala
    1               5                  10                  15

 cgt ggg gca gac ctc agg ccg cag tca cgg ggc tgc tca ggt gct gcg       96
 Arg Gly Ala Asp Leu Arg Pro Gln Ser Arg Gly Cys Ser Gly Ala Ala
              20                  25                  30

 atg gga gaa gag cca gga agt gag tct cca ccc agt gcc gct cag tca      144
 Met Gly Glu Glu Pro Gly Ser Glu Ser Pro Pro Ser Ala Ala Gln Ser
          35                  40                  45

 cgg gac cca gaa ctc act gaa ccg ccc acg tta atg acg cgc agt tcg      192
 Arg Asp Pro Glu Leu Thr Glu Pro Pro Thr Leu Met Thr Arg Ser Ser
      50                  55                  60

 ccg tgt gcc aat gac gcc tca atc aag ctg cta aac gaa ggc cgg agc      240
 Pro Cys Ala Asn Asp Ala Ser Ile Lys Leu Leu Asn Glu Gly Arg Ser
  65                  70                  75                  80

 agc cct gcc tgt ggg gct gta atg ttt tct gca gcc ttg atg agc cgc      288
 Ser Pro Ala Cys Gly Ala Val Met Phe Ser Ala Ala Leu Met Ser Arg
                  85                  90                  95

 cct ggg ctg ttt caa agg gaa cgc agc agt ctc ctc ttg act tcc gca      336
 Pro Gly Leu Phe Gln Arg Glu Arg Ser Ser Leu Leu Leu Thr Ser Ala
             100                 105                 110

 gtg gcc gta ttc ctg ggc cgt gcg gta aac agg gag tat cta ggc tcg      384
 Val Ala Val Phe Leu Gly Arg Ala Val Asn Arg Glu Tyr Leu Gly Ser
         115                 120                 125

 gat ggt tac aga cgg ctt tcc ccg tgg gcg gcg tcc cgt ggg ccc tat      432
 Asp Gly Tyr Arg Arg Leu Ser Pro Trp Ala Ala Ser Arg Gly Pro Tyr
     130                 135                 140

 gca agc tgc gca ggc cgc cct ggg ctc tgc cgc gag tgc gtg ggc ggc      480
 Ala Ser Cys Ala Gly Arg Pro Gly Leu Cys Arg Glu Cys Val Gly Gly
 145                 150                 155                 160

 agg acg gtg cat ccc ggg cct cca ccg gtc aaa tgc tcc aca ctg acc      528
 Arg Thr Val His Pro Gly Pro Pro Pro Val Lys Cys Ser Thr Leu Thr
                 165                 170                 175

 acc gca gca ccc ccc cgc tct ccc ggg caa att cta aag ctt ccc tag      576
 Thr Ala Ala Pro Pro Arg Ser Pro Gly Gln Ile Leu Lys Leu Pro 
             180                 185                 190





      <210> 531
      <211> 177
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(177)

      <400> 531
  atg gtg cag ttg gat gcc tgc ctc tct tgg gca ctg atg ggc tgg atc      48
  Met Val Gln Leu Asp Ala Cys Leu Ser Trp Ala Leu Met Gly Trp Ile
    1               5                  10                  15

 tgc ctg ctg cgg ctg tgc tcc gct ggc ctc tgg ggc tcc cgc tcc ctg       96
 Cys Leu Leu Arg Leu Cys Ser Ala Gly Leu Trp Gly Ser Arg Ser Leu
              20                  25                  30

 gga gtc agc tgg gca tca tgt tcc tgc acc ttt tca gaa gat gac aaa      144
 Gly Val Ser Trp Ala Ser Cys Ser Cys Thr Phe Ser Glu Asp Asp Lys
          35                  40                  45

 gtg cag gct tgc aag ggt gaa tgt ggc tgc tag                          177
 Val Gln Ala Cys Lys Gly Glu Cys Gly Cys 
      50                  55





      <210> 532
      <211> 348
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(348)

      <400> 532
  atg gtg gca agt ctc gtg ttc tct gac ctg ggg ttc ttg gcc tca cag      48
  Met Val Ala Ser Leu Val Phe Ser Asp Leu Gly Phe Leu Ala Ser Gln
    1               5                  10                  15

 ata cca agg aat gga atc ttg ggc cat gtg gta caa tgg caa gcc ttt       96
 Ile Pro Arg Asn Gly Ile Leu Gly His Val Val Gln Trp Gln Ala Phe
              20                  25                  30

 agc ccg atc ggg agt ggc aat ggg cgc ctt gct gga tca gga gca cag      144
 Ser Pro Ile Gly Ser Gly Asn Gly Arg Leu Ala Gly Ser Gly Ala Gln
          35                  40                  45

 cag aca ccc tac cgg atc cgg agt gat gga agt cag cgg cgg gtc tgc      192
 Gln Thr Pro Tyr Arg Ile Arg Ser Asp Gly Ser Gln Arg Arg Val Cys
      50                  55                  60

 gat ggt ggc aaa aca gca gtg gtg gac ata gca gaa gac aaa gaa cat      240
 Asp Gly Gly Lys Thr Ala Val Val Asp Ile Ala Glu Asp Lys Glu His
  65                  70                  75                  80

 aat ctc ctg gaa gcc cta tgg tcc tgc cca cca cct gag aaa ctt atc      288
 Asn Leu Leu Glu Ala Leu Trp Ser Cys Pro Pro Pro Glu Lys Leu Ile
                  85                  90                  95

 cag gtg acc cta ggg caa gcc tgt gcc ctt ctt ata cca ctg cag ctg      336
 Gln Val Thr Leu Gly Gln Ala Cys Ala Leu Leu Ile Pro Leu Gln Leu
             100                 105                 110

 atg ctc tct tga                                                      348
 Met Leu Ser 
         115





      <210> 533
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 533
  atg ccc cga ggg ctc ctg ctt gtg ttg cca gca cct gcc ctt ggg agc      48
  Met Pro Arg Gly Leu Leu Leu Val Leu Pro Ala Pro Ala Leu Gly Ser
    1               5                  10                  15

 cgt cag ctg ggg cca cga tgc tgg cag gcc agg cct ggt ctg gca ggg       96
 Arg Gln Leu Gly Pro Arg Cys Trp Gln Ala Arg Pro Gly Leu Ala Gly
              20                  25                  30

 agt gga ggc agg tgt cct tgc agg gag ggc ccg aag cca ggc tct gcc      144
 Ser Gly Gly Arg Cys Pro Cys Arg Glu Gly Pro Lys Pro Gly Ser Ala
          35                  40                  45

 ttg gag gat gct ccg gaa gga cca cat aag cag tgc cct cgt ttg gat      192
 Leu Glu Asp Ala Pro Glu Gly Pro His Lys Gln Cys Pro Arg Leu Asp
      50                  55                  60

 tgg tcc tgc ctg agc att gtc ccc aag cag ggc agt ttc agc cac tag      240
 Trp Ser Cys Leu Ser Ile Val Pro Lys Gln Gly Ser Phe Ser His 
  65                  70                  75





      <210> 534
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 534
  atg ccc act ttc aca ctt cta ttc agc ata tta ctg gaa gtt cta gcc      48
  Met Pro Thr Phe Thr Leu Leu Phe Ser Ile Leu Leu Glu Val Leu Ala
    1               5                  10                  15

 aga gca gtc aga caa gag aaa gaa aca aag gcc atc caa att agt aat       96
 Arg Ala Val Arg Gln Glu Lys Glu Thr Lys Ala Ile Gln Ile Ser Asn
              20                  25                  30

 gaa gaa gtc aaa ctg tcg ctg ttt gcc cat gat atg atc aca tac cta      144
 Glu Glu Val Lys Leu Ser Leu Phe Ala His Asp Met Ile Thr Tyr Leu
          35                  40                  45

 gaa aac tct aaa gac tca tcc aaa aag ctc cta gat ctg ata aag gaa      192
 Glu Asn Ser Lys Asp Ser Ser Lys Lys Leu Leu Asp Leu Ile Lys Glu
      50                  55                  60

 ttc agt aaa gtt tca gga tac aaa atc aat gta caa aaa tca gta gca      240
 Phe Ser Lys Val Ser Gly Tyr Lys Ile Asn Val Gln Lys Ser Val Ala
  65                  70                  75                  80

 ctg cta tac acc aac agc aac caa gct gag aat caa atc aaa acc tca      288
 Leu Leu Tyr Thr Asn Ser Asn Gln Ala Glu Asn Gln Ile Lys Thr Ser
                  85                  90                  95

 acc cct ttt ata aca gct gca aaa aat aat att ata aaa tac tta gga      336
 Thr Pro Phe Ile Thr Ala Ala Lys Asn Asn Ile Ile Lys Tyr Leu Gly
             100                 105                 110

 ata tac cta atc aaa gag gtg aaa gat ctc tac agg gaa aac tac caa      384
 Ile Tyr Leu Ile Lys Glu Val Lys Asp Leu Tyr Arg Glu Asn Tyr Gln
         115                 120                 125

 aca ctg ctg aac gaa atc ata gat gac aca aac aaa tag                  423
 Thr Leu Leu Asn Glu Ile Ile Asp Asp Thr Asn Lys 
     130                 135                 140





      <210> 535
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 535
  atg tgg act tct gcc ccc aac att gat gcc tta cta acc aag ctt gct      48
  Met Trp Thr Ser Ala Pro Asn Ile Asp Ala Leu Leu Thr Lys Leu Ala
    1               5                  10                  15

 gcc ttg gct cta tgc acc ctc ctg tac cag ctg gag gat gag tct gcg       96
 Ala Leu Ala Leu Cys Thr Leu Leu Tyr Gln Leu Glu Asp Glu Ser Ala
              20                  25                  30

 cat ttg gat gaa atg cca cta atg atg tct gaa gaa ggc ttt gag aat      144
 His Leu Asp Glu Met Pro Leu Met Met Ser Glu Glu Gly Phe Glu Asn
          35                  40                  45

 gag gaa agt gat tac cac acc tta cca cga gcc agg ata atg caa agg      192
 Glu Glu Ser Asp Tyr His Thr Leu Pro Arg Ala Arg Ile Met Gln Arg
      50                  55                  60

 aaa aga gga ctg gag tgg ttt gtc tgt gat ggc tgg aag ttc ctc tgt      240
 Lys Arg Gly Leu Glu Trp Phe Val Cys Asp Gly Trp Lys Phe Leu Cys
  65                  70                  75                  80

 acc agg ttt gtt atc cat tgc tac cta att tcc tta tat gct aag gtt      288
 Thr Arg Phe Val Ile His Cys Tyr Leu Ile Ser Leu Tyr Ala Lys Val
                  85                  90                  95

 act tat aag gtt agc ttc taa                                          309
 Thr Tyr Lys Val Ser Phe 
             100





      <210> 536
      <211> 1056
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1056)

      <400> 536
  atg acc act agt ggt cgt cat ggc ttg tgg tgg tca cgg ctt gtg ggg      48
  Met Thr Thr Ser Gly Arg His Gly Leu Trp Trp Ser Arg Leu Val Gly
    1               5                  10                  15

 gtc aca gct tgt ggc tgt agt ggc tgc tgc ggc atc act gcc acc ctg       96
 Val Thr Ala Cys Gly Cys Ser Gly Cys Cys Gly Ile Thr Ala Thr Leu
              20                  25                  30

 ggg gca gcc agg gtc agt cat gga cag ggc aca gct gcc cca gac cca      144
 Gly Ala Ala Arg Val Ser His Gly Gln Gly Thr Ala Ala Pro Asp Pro
          35                  40                  45

 tcc gct tgg ctc agt ctt tta cta gca agc cgt gtc cct ttg cga gtg      192
 Ser Ala Trp Leu Ser Leu Leu Leu Ala Ser Arg Val Pro Leu Arg Val
      50                  55                  60

 gta ggt ggc ctg cag gga tca gta gga ggc tgg aaa atg aat tgg agt      240
 Val Gly Gly Leu Gln Gly Ser Val Gly Gly Trp Lys Met Asn Trp Ser
  65                  70                  75                  80

 atg acg cca aaa gcc cta tgc cag gta ctt act agc cat tat tta tct      288
 Met Thr Pro Lys Ala Leu Cys Gln Val Leu Thr Ser His Tyr Leu Ser
                  85                  90                  95

 aag cag cct ttg gaa atc aag att atc tcc acc att ttg cca atg aaa      336
 Lys Gln Pro Leu Glu Ile Lys Ile Ile Ser Thr Ile Leu Pro Met Lys
             100                 105                 110

 aaa ctg aag ttc aac aag act gct ttt gaa ggt tat gaa gaa aac cca      384
 Lys Leu Lys Phe Asn Lys Thr Ala Phe Glu Gly Tyr Glu Glu Asn Pro
         115                 120                 125

 gac ttt cct gcc tac act ggt tcc cac cgg agc cag gag ctg ctc aga      432
 Asp Phe Pro Ala Tyr Thr Gly Ser His Arg Ser Gln Glu Leu Leu Arg
     130                 135                 140

 cag cag acc cag ccc agt cca ctg ggt ttt gca aac aca ggc tcc ctc      480
 Gln Gln Thr Gln Pro Ser Pro Leu Gly Phe Ala Asn Thr Gly Ser Leu
 145                 150                 155                 160

 tgc agc agc atg ggc ttg tgg aag gga ggc atg ccg ccg cca gca tgc      528
 Cys Ser Ser Met Gly Leu Trp Lys Gly Gly Met Pro Pro Pro Ala Cys
                 165                 170                 175

 atg cca ggg gtc cgg ggt tct ccc cgt gtc tgc aga ggt gag ggg tac      576
 Met Pro Gly Val Arg Gly Ser Pro Arg Val Cys Arg Gly Glu Gly Tyr
             180                 185                 190

 aaa ccc aag caa gca atc gga gtc att ctg ttt tta agg aag gtc agt      624
 Lys Pro Lys Gln Ala Ile Gly Val Ile Leu Phe Leu Arg Lys Val Ser
         195                 200                 205

 cgt tta aaa gat ttc tgg ttt gaa caa cat cct ctg tgg atg cac cag      672
 Arg Leu Lys Asp Phe Trp Phe Glu Gln His Pro Leu Trp Met His Gln
     210                 215                 220

 gcc aag gtg act acc ttt gac caa ccc agt gag aag gcc ttt gct ggt      720
 Ala Lys Val Thr Thr Phe Asp Gln Pro Ser Glu Lys Ala Phe Ala Gly
 225                 230                 235                 240

 ccc cgc agt gag gaa ctg gca gga acg ggc agc ctc ctc ccc gct gga      768
 Pro Arg Ser Glu Glu Leu Ala Gly Thr Gly Ser Leu Leu Pro Ala Gly
                 245                 250                 255

 ctg cac tgc cgg ggg ccg gtg ggc agg ctc cac agg cag ccc ctg tct      816
 Leu His Cys Arg Gly Pro Val Gly Arg Leu His Arg Gln Pro Leu Ser
             260                 265                 270

 gtg gcc aga cag gcc gtc ctg gtg act cgg gct tat aga ctg tgg ttt      864
 Val Ala Arg Gln Ala Val Leu Val Thr Arg Ala Tyr Arg Leu Trp Phe
         275                 280                 285

 aga act gca gaa gga gag agg aga gtg ggc cag gga aca ccc acc agg      912
 Arg Thr Ala Glu Gly Glu Arg Arg Val Gly Gln Gly Thr Pro Thr Arg
     290                 295                 300

 cgc tgc tct gac cag tca gag aac gtg agg cag ctc ccc cat agg gat      960
 Arg Cys Ser Asp Gln Ser Glu Asn Val Arg Gln Leu Pro His Arg Asp
 305                 310                 315                 320

 ctg cac cga gaa ggt gtg gaa ggc aca agc aag agt gac ggt acc aga     1008
 Leu His Arg Glu Gly Val Glu Gly Thr Ser Lys Ser Asp Gly Thr Arg
                 325                 330                 335

 gat ccc aga ggg cgt ggc tcg cgg cgg cca cag cag gcg cag cgc tga     1056
 Asp Pro Arg Gly Arg Gly Ser Arg Arg Pro Gln Gln Ala Gln Arg 
             340                 345                 350





      <210> 537
      <211> 729
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(729)

      <400> 537
  atg aag att atg atc ttt acc atg gcc tgt gag gct ctg ctg tat gat      48
  Met Lys Ile Met Ile Phe Thr Met Ala Cys Glu Ala Leu Leu Tyr Asp
    1               5                  10                  15

 ctg gcc ctt ccg tgc ctc tcc agc ttc att ccc acc tta atg cct acg       96
 Leu Ala Leu Pro Cys Leu Ser Ser Phe Ile Pro Thr Leu Met Pro Thr
              20                  25                  30

 aca ctg atg tcc ttt caa ggc ctt gaa tat gcc aag ctc ttt cct gct      144
 Thr Leu Met Ser Phe Gln Gly Leu Glu Tyr Ala Lys Leu Phe Pro Ala
          35                  40                  45

 tcc acg tct ttt tat gtg ctg ttc cct ctg tct agg gaa tac cta caa      192
 Ser Thr Ser Phe Tyr Val Leu Phe Pro Leu Ser Arg Glu Tyr Leu Gln
      50                  55                  60

 tac cca gac ttc ctt att ctt tac ctg gtc gtc ttt tat gta tcc ttc      240
 Tyr Pro Asp Phe Leu Ile Leu Tyr Leu Val Val Phe Tyr Val Ser Phe
  65                  70                  75                  80

 aac tct cag ttt aaa tac cac ttg ctt aag aaa tcc tct gat ctc cca      288
 Asn Ser Gln Phe Lys Tyr His Leu Leu Lys Lys Ser Ser Asp Leu Pro
                  85                  90                  95

 ggc aag aaa aat ttg ctg act ctt gat ata gag caa gaa aca att cat      336
 Gly Lys Lys Asn Leu Leu Thr Leu Asp Ile Glu Gln Glu Thr Ile His
             100                 105                 110

 gtt cgt gag gtg aag gat att cca aat gtc ttg gtt ggc act gca ttt      384
 Val Arg Glu Val Lys Asp Ile Pro Asn Val Leu Val Gly Thr Ala Phe
         115                 120                 125

 aat gtt gat gat gga aat ggg ggc ttt gta gtt cat tgg tta aac aac      432
 Asn Val Asp Asp Gly Asn Gly Gly Phe Val Val His Trp Leu Asn Asn
     130                 135                 140

 aag gaa ttt cat ttt aca tca tct aca gaa gta ttt atg cat caa tta      480
 Lys Glu Phe His Phe Thr Ser Ser Thr Glu Val Phe Met His Gln Leu
 145                 150                 155                 160

 cga aaa ctt tct gat aag cag gta gat cat gaa aat gat gat gca gat      528
 Arg Lys Leu Ser Asp Lys Gln Val Asp His Glu Asn Asp Asp Ala Asp
                 165                 170                 175

 aga gaa gat gag gaa cat tca cag gag gat aga gaa cgg ggt tta cat      576
 Arg Glu Asp Glu Glu His Ser Gln Glu Asp Arg Glu Arg Gly Leu His
             180                 185                 190

 atg aaa tta gac cat gag aat ctg agg cag gta cag gat cat cag aac      624
 Met Lys Leu Asp His Glu Asn Leu Arg Gln Val Gln Asp His Gln Asn
         195                 200                 205

 atg aag atg gag aaa gag aag gaa gtc cta gaa ctt act cac gac tta      672
 Met Lys Met Glu Lys Glu Lys Glu Val Leu Glu Leu Thr His Asp Leu
     210                 215                 220

 gtg tac caa tgc cac tgc cta cgg ttc tgc ttg atc gga aga ttg aaa      720
 Val Tyr Gln Cys His Cys Leu Arg Phe Cys Leu Ile Gly Arg Leu Lys
 225                 230                 235                 240

 tgc tgc taa                                                          729
 Cys Cys 






      <210> 538
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 538
  atg tcc atc ctc agg aca ctg ctg gct gca ttc ctg agg ctc cag ctc      48
  Met Ser Ile Leu Arg Thr Leu Leu Ala Ala Phe Leu Arg Leu Gln Leu
    1               5                  10                  15

 cgg cct tgg ctg aaa gat gca cag tct ttt cgc tta cac gga aag act       96
 Arg Pro Trp Leu Lys Asp Ala Gln Ser Phe Arg Leu His Gly Lys Thr
              20                  25                  30

 tct tca act gcc atg cat cag ggt cag ggg gag gtc ttg tta caa cac      144
 Ser Ser Thr Ala Met His Gln Gly Gln Gly Glu Val Leu Leu Gln His
          35                  40                  45

 aga tct gcg gat ctc cgg ggt ttg att gtg gca agg atg ctg ctg gtg      192
 Arg Ser Ala Asp Leu Arg Gly Leu Ile Val Ala Arg Met Leu Leu Val
      50                  55                  60

 tca aaa cca caa cgt ggg aac cac aga acc act agt tgg ttt tca gtg      240
 Ser Lys Pro Gln Arg Gly Asn His Arg Thr Thr Ser Trp Phe Ser Val
  65                  70                  75                  80

 ttt cag tgc ata caa ctc cta ata tat ctg gcc aag aaa act tat ctt      288
 Phe Gln Cys Ile Gln Leu Leu Ile Tyr Leu Ala Lys Lys Thr Tyr Leu
                  85                  90                  95

 cgc aga gcg gag cag cgg ccg gag ctt ttg gag gac tct gcg tgg act      336
 Arg Arg Ala Glu Gln Arg Pro Glu Leu Leu Glu Asp Ser Ala Trp Thr
             100                 105                 110

 tgg agc tca cag cgt ctt gcg act tgg aag cgg att cag agg aca gga      384
 Trp Ser Ser Gln Arg Leu Ala Thr Trp Lys Arg Ile Gln Arg Thr Gly
         115                 120                 125

 cag aac act tgg gca agt gaa ggg att gtg cat ctc cct ata tat tgt      432
 Gln Asn Thr Trp Ala Ser Glu Gly Ile Val His Leu Pro Ile Tyr Cys
     130                 135                 140

 cca taa                                                              438
 Pro 
 145





      <210> 539
      <211> 981
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(981)

      <400> 539
  atg tcc ttc ttt ttg gtg act gtt aac ata ctt ctt cac agt gca gag      48
  Met Ser Phe Phe Leu Val Thr Val Asn Ile Leu Leu His Ser Ala Glu
    1               5                  10                  15

 gag ctg cgg gcc cac cca ttc act gat gtt acc ctc tcc tgt cat ttc       96
 Glu Leu Arg Ala His Pro Phe Thr Asp Val Thr Leu Ser Cys His Phe
              20                  25                  30

 tcc ttt gtg aag ggc act gaa aat ctt gag ttt tct tgg gaa aga gaa      144
 Ser Phe Val Lys Gly Thr Glu Asn Leu Glu Phe Ser Trp Glu Arg Glu
          35                  40                  45

 gac atc aaa cag gca tat gag gta gag gat aat aaa gaa tat tac ctc      192
 Asp Ile Lys Gln Ala Tyr Glu Val Glu Asp Asn Lys Glu Tyr Tyr Leu
      50                  55                  60

 ctt ttc aag tac ctt gat ttt ttt gaa gtt ttc tcg aag ttg gtt tac      240
 Leu Phe Lys Tyr Leu Asp Phe Phe Glu Val Phe Ser Lys Leu Val Tyr
  65                  70                  75                  80

 cag ttt cac aat aac aca gag caa cta gaa gat caa aat tcc ttg tat      288
 Gln Phe His Asn Asn Thr Glu Gln Leu Glu Asp Gln Asn Ser Leu Tyr
                  85                  90                  95

 gag gga aga gta tct gtg gac cag gct gaa att tct gag ggg act cta      336
 Glu Gly Arg Val Ser Val Asp Gln Ala Glu Ile Ser Glu Gly Thr Leu
             100                 105                 110

 tca ctt tta cta aga aat gtg gat ttc atg gat gaa gct atc tac aag      384
 Ser Leu Leu Leu Arg Asn Val Asp Phe Met Asp Glu Ala Ile Tyr Lys
         115                 120                 125

 tgc tca gcc atc aca cca gat gga aga ggt gaa agt aca att aag cta      432
 Cys Ser Ala Ile Thr Pro Asp Gly Arg Gly Glu Ser Thr Ile Lys Leu
     130                 135                 140

 ata gta gaa gag agg gac ctg agc aac cac agc atc gtg gaa atc ctg      480
 Ile Val Glu Glu Arg Asp Leu Ser Asn His Ser Ile Val Glu Ile Leu
 145                 150                 155                 160

 gag gag cag atg aat ggc ttc tac agg gtg ttc tcc atc ctg aaa tac      528
 Glu Glu Gln Met Asn Gly Phe Tyr Arg Val Phe Ser Ile Leu Lys Tyr
                 165                 170                 175

 cct gtc aag tta aat gag aaa tat ctc tgc cac ata aca gag aca gat      576
 Pro Val Lys Leu Asn Glu Lys Tyr Leu Cys His Ile Thr Glu Thr Asp
             180                 185                 190

 gtg aac aac cag ctc ttc aga atc atc cac aag tat cca agc ccg gtg      624
 Val Asn Asn Gln Leu Phe Arg Ile Ile His Lys Tyr Pro Ser Pro Val
         195                 200                 205

 gtt ccc act agg aaa ccc tgg gac act tac ccc atc cct tgg gtt ttc      672
 Val Pro Thr Arg Lys Pro Trp Asp Thr Tyr Pro Ile Pro Trp Val Phe
     210                 215                 220

 cct tac cct tca cta cac ctg cta acc cac ttt tta att gaa act ttg      720
 Pro Tyr Pro Ser Leu His Leu Leu Thr His Phe Leu Ile Glu Thr Leu
 225                 230                 235                 240

 ctt ttt aaa tat ctc aat agc ggt agc ctg aat aat ggc ccc cca aaa      768
 Leu Phe Lys Tyr Leu Asn Ser Gly Ser Leu Asn Asn Gly Pro Pro Lys
                 245                 250                 255

 tat gtc tac att ctt atc cta gaa cct gtg aat gtt acc ttg ttg gac      816
 Tyr Val Tyr Ile Leu Ile Leu Glu Pro Val Asn Val Thr Leu Leu Asp
             260                 265                 270

 gaa aaa aag gtc ttt gca gag cac ctg ctt gag gta ggt tca aat cag      864
 Glu Lys Lys Val Phe Ala Glu His Leu Leu Glu Val Gly Ser Asn Gln
         275                 280                 285

 ccc tca agc cac agt gtg act aaa cac atc tat gcc cac aca gag agt      912
 Pro Ser Ser His Ser Val Thr Lys His Ile Tyr Ala His Thr Glu Ser
     290                 295                 300

 tca gga aat tca act cca cca cct gcc aag aca caa aac ctc act gta      960
 Ser Gly Asn Ser Thr Pro Pro Pro Ala Lys Thr Gln Asn Leu Thr Val
 305                 310                 315                 320

 ggc ctc tta gct tct tac tga                                          981
 Gly Leu Leu Ala Ser Tyr 
                 325





      <210> 540
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 540
  atg gta gtt gtt gaa ggc atg ttt gtg ata gta gcc cag ctc aaa ggc      48
  Met Val Val Val Glu Gly Met Phe Val Ile Val Ala Gln Leu Lys Gly
    1               5                  10                  15

 ttc caa gga ggc tgc aag atc ttc atc att gtg gaa ctc agg att ctc       96
 Phe Gln Gly Gly Cys Lys Ile Phe Ile Ile Val Glu Leu Arg Ile Leu
              20                  25                  30

 ttc aca ctt gcc ttc ccc atc ccg ttc cac atc agc gat gtc aaa gag      144
 Phe Thr Leu Ala Phe Pro Ile Pro Phe His Ile Ser Asp Val Lys Glu
          35                  40                  45

 gcc atg ctg tct gtc ata ctg tcc atg tcc tgt tct gct att atg tca      192
 Ala Met Leu Ser Val Ile Leu Ser Met Ser Cys Ser Ala Ile Met Ser
      50                  55                  60

 cca caa cct gtc aat gaa tca aag ctt ttc agg gat gtc aca tcc cca      240
 Pro Gln Pro Val Asn Glu Ser Lys Leu Phe Arg Asp Val Thr Ser Pro
  65                  70                  75                  80

 aac aag agg ctc aat agg ttt gag tgg ccc aaa aac gag aaa cct gcc      288
 Asn Lys Arg Leu Asn Arg Phe Glu Trp Pro Lys Asn Glu Lys Pro Ala
                  85                  90                  95

 aac gtg gac aaa gat gca gaa ttt gag cta ttt gaa gaa aat gac tta      336
 Asn Val Asp Lys Asp Ala Glu Phe Glu Leu Phe Glu Glu Asn Asp Leu
             100                 105                 110

 tca gat gat ctg gaa ctt gaa tga                                      360
 Ser Asp Asp Leu Glu Leu Glu 
         115





      <210> 541
      <211> 120
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(120)

      <400> 541
  atg aaa gga gga ggc tca ctc att gcg act gcc ctt ctt cta cgt act      48
  Met Lys Gly Gly Gly Ser Leu Ile Ala Thr Ala Leu Leu Leu Arg Thr
    1               5                  10                  15

 ggg aat ttg ttg gat cct gtg gac aac gac aaa tgc atc gga cag tcc       96
 Gly Asn Leu Leu Asp Pro Val Asp Asn Asp Lys Cys Ile Gly Gln Ser
              20                  25                  30

 gac ttt cac tgg atg att ggt tga                                      120
 Asp Phe His Trp Met Ile Gly 
          35





      <210> 542
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 542
  atg gca ggg gcc tgc tgg ctg atg gca ttc cag tac tgg gtt gtg aag      48
  Met Ala Gly Ala Cys Trp Leu Met Ala Phe Gln Tyr Trp Val Val Lys
    1               5                  10                  15

 ttg ctt gtg gtg aaa tca gca tat ggc ctc ctc aaa gct ctc gca aat       96
 Leu Leu Val Val Lys Ser Ala Tyr Gly Leu Leu Lys Ala Leu Ala Asn
              20                  25                  30

 gga att gga att tca gag gtt gcc aag acc tgg aat cct ggg gaa aaa      144
 Gly Ile Gly Ile Ser Glu Val Ala Lys Thr Trp Asn Pro Gly Glu Lys
          35                  40                  45

 aag aga ctc ccc gcc atg tcg cca agt gaa tcc atc ctg ccg tcc gtc      192
 Lys Arg Leu Pro Ala Met Ser Pro Ser Glu Ser Ile Leu Pro Ser Val
      50                  55                  60

 tcc act ttc gcc agc ccg tac cgc aag cgc cgc ctg cag gag cgc tga      240
 Ser Thr Phe Ala Ser Pro Tyr Arg Lys Arg Arg Leu Gln Glu Arg 
  65                  70                  75





      <210> 543
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 543
  atg tta gtg gtt ctg gct tta acc ctc ttc tca ttc aca gtc gta gtc      48
  Met Leu Val Val Leu Ala Leu Thr Leu Phe Ser Phe Thr Val Val Val
    1               5                  10                  15

 ctt aac tct att agg gct atg gtc ccc tct gaa cgc ata ttt aaa gcg       96
 Leu Asn Ser Ile Arg Ala Met Val Pro Ser Glu Arg Ile Phe Lys Ala
              20                  25                  30

 aaa gat ctt ctt tct aga aaa ata cac att cac att tat gat aaa aat      144
 Lys Asp Leu Leu Ser Arg Lys Ile His Ile His Ile Tyr Asp Lys Asn
          35                  40                  45

 att gca tac gag tcg gca gtt ccc att atg cca gtg att cct caa act      192
 Ile Ala Tyr Glu Ser Ala Val Pro Ile Met Pro Val Ile Pro Gln Thr
      50                  55                  60

 gga tct cca act tat acc tcc agt gcg gcg ctc cca caa tgc tta act      240
 Gly Ser Pro Thr Tyr Thr Ser Ser Ala Ala Leu Pro Gln Cys Leu Thr
  65                  70                  75                  80

 cca gga aac acc att cac agt gta gcc att gtg aat ggc agt tct tgg      288
 Pro Gly Asn Thr Ile His Ser Val Ala Ile Val Asn Gly Ser Ser Trp
                  85                  90                  95

 agt agc gca cta cgt agc cag tgt gac cac aga ctg cat act tgc agc      336
 Ser Ser Ala Leu Arg Ser Gln Cys Asp His Arg Leu His Thr Cys Ser
             100                 105                 110

 ttt acc cta gtg cct cag agg cat cct cac acc cag ctc atc tga          381
 Phe Thr Leu Val Pro Gln Arg His Pro His Thr Gln Leu Ile 
         115                 120                 125





      <210> 544
      <211> 597
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(597)

      <400> 544
  atg att agt gtt cag ctc ttt gta ttt cct ccc ctt ggt ggt gtg atg      48
  Met Ile Ser Val Gln Leu Phe Val Phe Pro Pro Leu Gly Gly Val Met
    1               5                  10                  15

 gtc tta caa tgc tcc ctc ttt gca aat acc tat atc aaa agc tgg gaa       96
 Val Leu Gln Cys Ser Leu Phe Ala Asn Thr Tyr Ile Lys Ser Trp Glu
              20                  25                  30

 aat ggg aac aca cgg ttc aga gaa ctc ccc ctg gcg tca ctc tgt act      144
 Asn Gly Asn Thr Arg Phe Arg Glu Leu Pro Leu Ala Ser Leu Cys Thr
          35                  40                  45

 acc tct ctt tct gaa act gaa tct ggt ccc cct gct cag gag cac aga      192
 Thr Ser Leu Ser Glu Thr Glu Ser Gly Pro Pro Ala Gln Glu His Arg
      50                  55                  60

 gac cag ccc gga agc cga cct tgg gca gct gcc gcc acc cag gga agg      240
 Asp Gln Pro Gly Ser Arg Pro Trp Ala Ala Ala Ala Thr Gln Gly Arg
  65                  70                  75                  80

 gaa cag ttg gaa gct ttg gtg ttc gcc cac cgc gcc aag agg aac tct      288
 Glu Gln Leu Glu Ala Leu Val Phe Ala His Arg Ala Lys Arg Asn Ser
                  85                  90                  95

 tcc cgt ttg tgc agc tcc cct ggc tcg gca ctt ggt atc tcc cac ggt      336
 Ser Arg Leu Cys Ser Ser Pro Gly Ser Ala Leu Gly Ile Ser His Gly
             100                 105                 110

 ctt gct ctc tgt ggg aag ccg gaa aga aga ctg ctg tgg gcg tcg ccg      384
 Leu Ala Leu Cys Gly Lys Pro Glu Arg Arg Leu Leu Trp Ala Ser Pro
         115                 120                 125

 cca ccc ctc ccg gaa cca gag cct gct cta gcg tgc atc caa gcc tcc      432
 Pro Pro Leu Pro Glu Pro Glu Pro Ala Leu Ala Cys Ile Gln Ala Ser
     130                 135                 140

 tac ttc aga ctc aca tct ggc cca gtc gga cag atg tta gcc gct gga      480
 Tyr Phe Arg Leu Thr Ser Gly Pro Val Gly Gln Met Leu Ala Ala Gly
 145                 150                 155                 160

 gag tgc ctc cat gcg aag cgc ccc aag tcc cga gca tgc cca gtc gga      528
 Glu Cys Leu His Ala Lys Arg Pro Lys Ser Arg Ala Cys Pro Val Gly
                 165                 170                 175

 cta cta agg ctt ctg acg cga gtt tct ggg cgt gca gat tcc gct tct      576
 Leu Leu Arg Leu Leu Thr Arg Val Ser Gly Arg Ala Asp Ser Ala Ser
             180                 185                 190

 ccg ctt ttt cga gga agc tga                                          597
 Pro Leu Phe Arg Gly Ser 
         195





      <210> 545
      <211> 291
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(291)

      <400> 545
  atg ggg tgg ccc agg gac aga gag ctg ctc atc aaa atc agt gtc aaa      48
  Met Gly Trp Pro Arg Asp Arg Glu Leu Leu Ile Lys Ile Ser Val Lys
    1               5                  10                  15

 gct gca tgt gca gcc ctg gtg ctc ggg ggg ctc tgg tgc agg gtg tgc       96
 Ala Ala Cys Ala Ala Leu Val Leu Gly Gly Leu Trp Cys Arg Val Cys
              20                  25                  30

 tgt ggc gtt cct cga cga cga tgt tgc ttt act ggg gga agt atc ctg      144
 Cys Gly Val Pro Arg Arg Arg Cys Cys Phe Thr Gly Gly Ser Ile Leu
          35                  40                  45

 gta ctg gca ggg tca gaa gag ggt agt gag gag aac agt gga ggg aga      192
 Val Leu Ala Gly Ser Glu Glu Gly Ser Glu Glu Asn Ser Gly Gly Arg
      50                  55                  60

 atg aaa gaa ggc aca gtt tca cct tct cca tct gcc ttg gaa gcc gca      240
 Met Lys Glu Gly Thr Val Ser Pro Ser Pro Ser Ala Leu Glu Ala Ala
  65                  70                  75                  80

 aca tct gcc ttc caa tta gga tgg agt tac cgg ggt gac ggg gtt ggc      288
 Thr Ser Ala Phe Gln Leu Gly Trp Ser Tyr Arg Gly Asp Gly Val Gly
                  85                  90                  95

 tag                                                                  291
 






      <210> 546
      <211> 690
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(690)

      <400> 546
  atg gtg gcc atg gcc agc agc tgg atg tcc gag tgg gca ttg gcc acc      48
  Met Val Ala Met Ala Ser Ser Trp Met Ser Glu Trp Ala Leu Ala Thr
    1               5                  10                  15

 gtg tgc cgc cgc acg ctg cca cac ttc tcc agc ctc ctt ttc tgc cag       96
 Val Cys Arg Arg Thr Leu Pro His Phe Ser Ser Leu Leu Phe Cys Gln
              20                  25                  30

 agc aca cct ctt ccc agc ttc cca gtc aca tac acc att tca cct gtc      144
 Ser Thr Pro Leu Pro Ser Phe Pro Val Thr Tyr Thr Ile Ser Pro Val
          35                  40                  45

 tct gcc ttc cac agt gcc cat atc tct gac acc ctg aag acc caa gag      192
 Ser Ala Phe His Ser Ala His Ile Ser Asp Thr Leu Lys Thr Gln Glu
      50                  55                  60

 aaa gac aca tgc agc atc ttt gta gga aat gag aat tcg tca gat gat      240
 Lys Asp Thr Cys Ser Ile Phe Val Gly Asn Glu Asn Ser Ser Asp Asp
  65                  70                  75                  80

 ttc cgc agg tcc cag ccc act ggg atg agc cag gga aag gtg tct cca      288
 Phe Arg Arg Ser Gln Pro Thr Gly Met Ser Gln Gly Lys Val Ser Pro
                  85                  90                  95

 gtg atc ctt gga ggg ccc agg cag caa atg gac aag aga agc cac tct      336
 Val Ile Leu Gly Gly Pro Arg Gln Gln Met Asp Lys Arg Ser His Ser
             100                 105                 110

 ggc tgc tca cag gcc aag agc tgg agc cag agg ggg gct gcc ctg gag      384
 Gly Cys Ser Gln Ala Lys Ser Trp Ser Gln Arg Gly Ala Ala Leu Glu
         115                 120                 125

 gag gag acc aca aca cca cct gtc ccc acc ttc aac aaa cac tac tac      432
 Glu Glu Thr Thr Thr Pro Pro Val Pro Thr Phe Asn Lys His Tyr Tyr
     130                 135                 140

 ctg tac atg caa aat gct gca cta gct gca gag aag aaa aga aac ata      480
 Leu Tyr Met Gln Asn Ala Ala Leu Ala Ala Glu Lys Lys Arg Asn Ile
 145                 150                 155                 160

 aat ctg atg tgg ggc ccc caa cag ggg ctt gag ccc agc aca ctt gtg      528
 Asn Leu Met Trp Gly Pro Gln Gln Gly Leu Glu Pro Ser Thr Leu Val
                 165                 170                 175

 tac ctc cat gca tgc tcc ctg gcc agg ccc cac cgg agc gac cgc cat      576
 Tyr Leu His Ala Cys Ser Leu Ala Arg Pro His Arg Ser Asp Arg His
             180                 185                 190

 aat aag gcc att gtg acc cca gca cac caa gcc cgt ggt ggg tgt ccc      624
 Asn Lys Ala Ile Val Thr Pro Ala His Gln Ala Arg Gly Gly Cys Pro
         195                 200                 205

 tct cca ggc tgg cac ctg aaa gcc gtg aat gct ggc ttg tca cgc aga      672
 Ser Pro Gly Trp His Leu Lys Ala Val Asn Ala Gly Leu Ser Arg Arg
     210                 215                 220

 gaa gct aca gta tcc tga                                              690
 Glu Ala Thr Val Ser 
 225





      <210> 547
      <211> 303
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(303)

      <400> 547
  atg aag gtt ttg cgt ttt acc ctg gag ctg gtg gga gcc atg ggg tgc      48
  Met Lys Val Leu Arg Phe Thr Leu Glu Leu Val Gly Ala Met Gly Cys
    1               5                  10                  15

 act gca gca ggg agt gac caa cgc cag ctt tgt gta ttg gaa gga ttt       96
 Thr Ala Ala Gly Ser Asp Gln Arg Gln Leu Cys Val Leu Glu Gly Phe
              20                  25                  30

 cta cat cag aca gga ctc tct tgg ttt gca aag gac aga aaa ccc aac      144
 Leu His Gln Thr Gly Leu Ser Trp Phe Ala Lys Asp Arg Lys Pro Asn
          35                  40                  45

 tca aaa tgg ctt aaa agc aaa aca gaa ttc act ggt aca ttt gac aga      192
 Ser Lys Trp Leu Lys Ser Lys Thr Glu Phe Thr Gly Thr Phe Asp Arg
      50                  55                  60

 atg gtc tgt ggg gtt gga tgg cct cag gcc atc gtg cat aac cag ccc      240
 Met Val Cys Gly Val Gly Trp Pro Gln Ala Ile Val His Asn Gln Pro
  65                  70                  75                  80

 ctt cag aat gcg ctg ctg agc agt ccc tgg gcg gtg ttc gtg agc acg      288
 Leu Gln Asn Ala Leu Leu Ser Ser Pro Trp Ala Val Phe Val Ser Thr
                  85                  90                  95

 ttt ctc att tat taa                                                  303
 Phe Leu Ile Tyr 
             100





      <210> 548
      <211> 285
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(285)

      <400> 548
  atg aag aaa gtt cta gca atg ttc tta ttt cca gta ctt gga ctc ata      48
  Met Lys Lys Val Leu Ala Met Phe Leu Phe Pro Val Leu Gly Leu Ile
    1               5                  10                  15

 gat tcg cgt tcg aat gat ctt ctc cac cag ata ttg agg gtt ggt gcc       96
 Asp Ser Arg Ser Asn Asp Leu Leu His Gln Ile Leu Arg Val Gly Ala
              20                  25                  30

 atg gat gct gtg cgc atc ctt cac tgt acg gtt agc cat ttt aga atg      144
 Met Asp Ala Val Arg Ile Leu His Cys Thr Val Ser His Phe Arg Met
          35                  40                  45

 cct tca att cta ttt ccg tcg gat cct tta atg cct cac atc cag gtt      192
 Pro Ser Ile Leu Phe Pro Ser Asp Pro Leu Met Pro His Ile Gln Val
      50                  55                  60

 cag aaa aag cac cta gag gaa tgg aga aag gtg gaa gaa gtt tca cta      240
 Gln Lys Lys His Leu Glu Glu Trp Arg Lys Val Glu Glu Val Ser Leu
  65                  70                  75                  80

 aac agc tta ggc gac cat ctt gaa gcc gga aac acc gta gtg taa          285
 Asn Ser Leu Gly Asp His Leu Glu Ala Gly Asn Thr Val Val 
                  85                  90





      <210> 549
      <211> 255
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(255)

      <400> 549
  atg tct gcc ctc act aac atg aca aaa gaa cct tgg aac acc ttc ata      48
  Met Ser Ala Leu Thr Asn Met Thr Lys Glu Pro Trp Asn Thr Phe Ile
    1               5                  10                  15

 ctc att act tac cta tta cct tac atg ctg tta tct gat agg acc cac       96
 Leu Ile Thr Tyr Leu Leu Pro Tyr Met Leu Leu Ser Asp Arg Thr His
              20                  25                  30

 ctg cag tca aaa ttt ttc aca aag gca tca ggc atc aac cag tca gaa      144
 Leu Gln Ser Lys Phe Phe Thr Lys Ala Ser Gly Ile Asn Gln Ser Glu
          35                  40                  45

 tca tgg gca gtg caa gaa ggt cct gga gac att cca gcc ctg ccc agg      192
 Ser Trp Ala Val Gln Glu Gly Pro Gly Asp Ile Pro Ala Leu Pro Arg
      50                  55                  60

 cat gac tac caa aat acc ata gat ggc act gtg ttc ttc cat cag gaa      240
 His Asp Tyr Gln Asn Thr Ile Asp Gly Thr Val Phe Phe His Gln Glu
  65                  70                  75                  80

 gca cat gat gtt tag                                                  255
 Ala His Asp Val 






      <210> 550
      <211> 459
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(459)

      <400> 550
  atg cct agg ctt ggc atg ttg tgg tgg ctg ctg ttt gta ttg atg cta      48
  Met Pro Arg Leu Gly Met Leu Trp Trp Leu Leu Phe Val Leu Met Leu
    1               5                  10                  15

 ctg tta ttc acc ctt gac ctt tgc aca gca ttt gac agg tac aag gga       96
 Leu Leu Phe Thr Leu Asp Leu Cys Thr Ala Phe Asp Arg Tyr Lys Gly
              20                  25                  30

 cag aca tta gct ccc ttt ccg cag tgc ctg caa gaa cct gca ggg ggc      144
 Gln Thr Leu Ala Pro Phe Pro Gln Cys Leu Gln Glu Pro Ala Gly Gly
          35                  40                  45

 gca gag cct gag ggc ctg aag gaa gga gag aca cgg atg tcc gcc ggg      192
 Ala Glu Pro Glu Gly Leu Lys Glu Gly Glu Thr Arg Met Ser Ala Gly
      50                  55                  60

 ctt ccc cgg aag aca tat cct ggg gtc ctc tcc ctc aag gct cag tcc      240
 Leu Pro Arg Lys Thr Tyr Pro Gly Val Leu Ser Leu Lys Ala Gln Ser
  65                  70                  75                  80

 tcg gaa cta gtc tgg aaa tgg ccc ctc acc tgt ggg ctt gat acc tgg      288
 Ser Glu Leu Val Trp Lys Trp Pro Leu Thr Cys Gly Leu Asp Thr Trp
                  85                  90                  95

 gac ttt gat aca tgg aaa ctc ctg aag agg cag atg gca gaa gat ttc      336
 Asp Phe Asp Thr Trp Lys Leu Leu Lys Arg Gln Met Ala Glu Asp Phe
             100                 105                 110

 atg gag gca aag aag aag cca aca ccc aac agt gtg gct cct ggc act      384
 Met Glu Ala Lys Lys Lys Pro Thr Pro Asn Ser Val Ala Pro Gly Thr
         115                 120                 125

 atg ctg ggg aca cat ttt gga gac agc agc act tct gcg gcc tcc ttg      432
 Met Leu Gly Thr His Phe Gly Asp Ser Ser Thr Ser Ala Ala Ser Leu
     130                 135                 140

 tgc tat gaa gat ctt ttg gca gcc tag                                  459
 Cys Tyr Glu Asp Leu Leu Ala Ala 
 145                 150





      <210> 551
      <211> 945
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(945)

      <400> 551
  atg ctg tcc ttt gtc cca tct ctg att ctg tgc tta ctg tgc cca agt      48
  Met Leu Ser Phe Val Pro Ser Leu Ile Leu Cys Leu Leu Cys Pro Ser
    1               5                  10                  15

 atg gaa ttg cag ggt agc agc atg ggg act tcc agg ccc ctg atg tct       96
 Met Glu Leu Gln Gly Ser Ser Met Gly Thr Ser Arg Pro Leu Met Ser
              20                  25                  30

 gcg tcc agc gag gcc tct ggt ggt gtc agc atg ttt gtg tgg agg aat      144
 Ala Ser Ser Glu Ala Ser Gly Gly Val Ser Met Phe Val Trp Arg Asn
          35                  40                  45

 gtg gaa cct tgc tct gtg gct gtg ttc tcc tgg tac tct gtc ccc ttc      192
 Val Glu Pro Cys Ser Val Ala Val Phe Ser Trp Tyr Ser Val Pro Phe
      50                  55                  60

 ctg acc cct ccc tgc agc cgc gtg agg ccc agc aac ctg cca gtc act      240
 Leu Thr Pro Pro Cys Ser Arg Val Arg Pro Ser Asn Leu Pro Val Thr
  65                  70                  75                  80

 cag tgg cct cca acc aga gca aag aac ctg cca agt cgg cag ctg ttg      288
 Gln Trp Pro Pro Thr Arg Ala Lys Asn Leu Pro Ser Arg Gln Leu Leu
                  85                  90                  95

 ctc acg agt gtc cac cag gcc cag tcc ctc agt gcc ctg tgc aag gaa      336
 Leu Thr Ser Val His Gln Ala Gln Ser Leu Ser Ala Leu Cys Lys Glu
             100                 105                 110

 cag gac tca tct tct gag aag gat gga cgc agc ccc aac aaa tgg gac      384
 Gln Asp Ser Ser Ser Glu Lys Asp Gly Arg Ser Pro Asn Lys Trp Asp
         115                 120                 125

 aag gac cac atc tgg tgg ccc atg agt ggc ggt cac gat ctt cag caa      432
 Lys Asp His Ile Trp Trp Pro Met Ser Gly Gly His Asp Leu Gln Gln
     130                 135                 140

 gcg gca cca ggc cct ggc agg gcg cac cag ggt cac ccc tac cag gat      480
 Ala Ala Pro Gly Pro Gly Arg Ala His Gln Gly His Pro Tyr Gln Asp
 145                 150                 155                 160

 aac tgg acc atc agc cag atc ctg agc gag cgg tgg tac acc ctg ggg      528
 Asn Trp Thr Ile Ser Gln Ile Leu Ser Glu Arg Trp Tyr Thr Leu Gly
                 165                 170                 175

 ccc aat gag atg cag aag tac cac gac ctg gcc ttc cag cac atg gcc      576
 Pro Asn Glu Met Gln Lys Tyr His Asp Leu Ala Phe Gln His Met Ala
             180                 185                 190

 ggt gag gac aca gcg agt gac gag gag cac atg gtc atc cat gag gag      624
 Gly Glu Asp Thr Ala Ser Asp Glu Glu His Met Val Ile His Glu Glu
         195                 200                 205

 gag ggg gtg atg atg tca ttg ctg atg acg gct tta gca cca ctg aca      672
 Glu Gly Val Met Met Ser Leu Leu Met Thr Ala Leu Ala Pro Leu Thr
     210                 215                 220

 ctg atc tca agt tca agg att ttt ggc aaa gtc tat ggt ccc acc ccg      720
 Leu Ile Ser Ser Ser Arg Ile Phe Gly Lys Val Tyr Gly Pro Thr Pro
 225                 230                 235                 240

 tcc tcc tcc tac aca tac tcg gat gct tcc tcc tca acc ttg gca ccc      768
 Ser Ser Ser Tyr Thr Tyr Ser Asp Ala Ser Ser Ser Thr Leu Ala Pro
                 245                 250                 255

 acc tcc ttc tta ctg ggc cca gga gcc ttc aaa gcc cag gag tct ggt      816
 Thr Ser Phe Leu Leu Gly Pro Gly Ala Phe Lys Ala Gln Glu Ser Gly
             260                 265                 270

 gaa gcc gag gac ggt ctc agg aaa ctg gag acc gag aag gcg ctg tcc      864
 Glu Ala Glu Asp Gly Leu Arg Lys Leu Glu Thr Glu Lys Ala Leu Ser
         275                 280                 285

 tct tca ctg cac gcg ccc tgg act agt gcc ggc cct gat cat gca gct      912
 Ser Ser Leu His Ala Pro Trp Thr Ser Ala Gly Pro Asp His Ala Ala
     290                 295                 300

 ctt cca ggc cca ctg ctt ctt cct gtc cac tag                          945
 Leu Pro Gly Pro Leu Leu Leu Pro Val His 
 305                 310





      <210> 552
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 552
  atg tca gcc tat tgc ttt cag ttc aca tcc tcc cag ttt tac tac cag      48
  Met Ser Ala Tyr Cys Phe Gln Phe Thr Ser Ser Gln Phe Tyr Tyr Gln
    1               5                  10                  15

 aaa agg aaa ttg ctc ttt ttc cta gct gca ctt cag tta atc ctg gct       96
 Lys Arg Lys Leu Leu Phe Phe Leu Ala Ala Leu Gln Leu Ile Leu Ala
              20                  25                  30

 aag atc ata att gag tct tca gta agc cat ttc acc att cag tta tgc      144
 Lys Ile Ile Ile Glu Ser Ser Val Ser His Phe Thr Ile Gln Leu Cys
          35                  40                  45

 cag ctg ctt cca aat gat ggt ata tat gcg tct agt cta ttt att gtc      192
 Gln Leu Leu Pro Asn Asp Gly Ile Tyr Ala Ser Ser Leu Phe Ile Val
      50                  55                  60

 gcg ggg aag ctg cgg ccg cct cgc acc cgg aac aac aaa gca agg aag      240
 Ala Gly Lys Leu Arg Pro Pro Arg Thr Arg Asn Asn Lys Ala Arg Lys
  65                  70                  75                  80

 acg gag tcc gag cct cgg ggg ctc cta gca acg ggc cgg ggc ggg agt      288
 Thr Glu Ser Glu Pro Arg Gly Leu Leu Ala Thr Gly Arg Gly Gly Ser
                  85                  90                  95

 tcc atg gag act ggg gag cgc gcc cgt ctc atc ctc atc ctt gtc ctc      336
 Ser Met Glu Thr Gly Glu Arg Ala Arg Leu Ile Leu Ile Leu Val Leu
             100                 105                 110

 cag ctt ctc ctt cgc atc cga cgc aac cgg cag cag cgc tgc cgc cgc      384
 Gln Leu Leu Leu Arg Ile Arg Arg Asn Arg Gln Gln Arg Cys Arg Arg
         115                 120                 125

 gtc ctc agc cac cgc tcc ctc ttc cca cgg taa                          417
 Val Leu Ser His Arg Ser Leu Phe Pro Arg 
     130                 135





      <210> 553
      <211> 420
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(420)

      <400> 553
  atg ccc tca ggg aag att cta tgt att cac tgt ctg ggg ctg ctc aag      48
  Met Pro Ser Gly Lys Ile Leu Cys Ile His Cys Leu Gly Leu Leu Lys
    1               5                  10                  15

 cca ctg ctc tgc gca gcc ctg cct ccc act ggc ctt ctc aat ggc ttt       96
 Pro Leu Leu Cys Ala Ala Leu Pro Pro Thr Gly Leu Leu Asn Gly Phe
              20                  25                  30

 ccg ctc agg gaa ccc ctg cag cct gta gtc tcc agg cag gcc ttg ggc      144
 Pro Leu Arg Glu Pro Leu Gln Pro Val Val Ser Arg Gln Ala Leu Gly
          35                  40                  45

 cac cag gct gga gag agc cgc ggc cac act cag cgg tgc aag gtg acc      192
 His Gln Ala Gly Glu Ser Arg Gly His Thr Gln Arg Cys Lys Val Thr
      50                  55                  60

 cgg ctg tct tcc tgg cag gtc ctc gtg gga gcg gct gtc cct tgt tca      240
 Arg Leu Ser Ser Trp Gln Val Leu Val Gly Ala Ala Val Pro Cys Ser
  65                  70                  75                  80

 ggg gcc cgg gac cgc gtc ccc gtc ccc cga cat gtc ccc caa gca tgc      288
 Gly Ala Arg Asp Arg Val Pro Val Pro Arg His Val Pro Gln Ala Cys
                  85                  90                  95

 ctt cag ggc agg gtg cag act gga agg ctg gac tgg cgg gga cac gcg      336
 Leu Gln Gly Arg Val Gln Thr Gly Arg Leu Asp Trp Arg Gly His Ala
             100                 105                 110

 tgt tct gca tct cct aac gct gtg ccc act gtg ggt ggg acg gtg act      384
 Cys Ser Ala Ser Pro Asn Ala Val Pro Thr Val Gly Gly Thr Val Thr
         115                 120                 125

 ggc ttg ggt ggg gtc caa ggc ggg ggt gac gaa tga                      420
 Gly Leu Gly Gly Val Gln Gly Gly Gly Asp Glu 
     130                 135





      <210> 554
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 554
  atg gtg tct gga cag gca ggc agg gcc agt gga gga gct gat atc acc      48
  Met Val Ser Gly Gln Ala Gly Arg Ala Ser Gly Gly Ala Asp Ile Thr
    1               5                  10                  15

 cct ttt gtt ttc aaa ccc ttc ttg gtc ttt ttg gta agc tcg ctt tcc       96
 Pro Phe Val Phe Lys Pro Phe Leu Val Phe Leu Val Ser Ser Leu Ser
              20                  25                  30

 ttg ggt tcc act tcg tcc gag ggc ttg gag gct gtg tct ttg ctg ctt      144
 Leu Gly Ser Thr Ser Ser Glu Gly Leu Glu Ala Val Ser Leu Leu Leu
          35                  40                  45

 ggg cca ggc tcc tca gaa ctg tat tcc cct ccc aaa gac aga aaa cgc      192
 Gly Pro Gly Ser Ser Glu Leu Tyr Ser Pro Pro Lys Asp Arg Lys Arg
      50                  55                  60

 acc agc act ttc tgc ctg aat gtc tgt cgg gaa aac gtc atg aag gat      240
 Thr Ser Thr Phe Cys Leu Asn Val Cys Arg Glu Asn Val Met Lys Asp
  65                  70                  75                  80

 gtc agt att gcc att gta ttg ttt cag ctg gca gtg gca ggt ggc ccc      288
 Val Ser Ile Ala Ile Val Leu Phe Gln Leu Ala Val Ala Gly Gly Pro
                  85                  90                  95

 cac gag tcc ccc gtg tgc tat gca aac ggt tga                          321
 His Glu Ser Pro Val Cys Tyr Ala Asn Gly 
             100                 105





      <210> 555
      <211> 273
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(273)

      <400> 555
  atg gag tgg cgg ctt ctg agc gcc ttc gtg gca tgt gtc tgt gga aag      48
  Met Glu Trp Arg Leu Leu Ser Ala Phe Val Ala Cys Val Cys Gly Lys
    1               5                  10                  15

 gcc ttg tgt gat gta ttg agt cca gtg gac tcg gtt cat tca ttc agt       96
 Ala Leu Cys Asp Val Leu Ser Pro Val Asp Ser Val His Ser Phe Ser
              20                  25                  30

 gcc ctc ttt gtg ctg gca ttg act caa gac aag aaa aac tgg gga cca      144
 Ala Leu Phe Val Leu Ala Leu Thr Gln Asp Lys Lys Asn Trp Gly Pro
          35                  40                  45

 gag aag tta ggc cat gca gct gtg agg gtg aag gtt tgc acg act cca      192
 Glu Lys Leu Gly His Ala Ala Val Arg Val Lys Val Cys Thr Thr Pro
      50                  55                  60

 aag ccc aca tgt ccc tat gct gat cac gtg ctg ccg ctc act ctt aac      240
 Lys Pro Thr Cys Pro Tyr Ala Asp His Val Leu Pro Leu Thr Leu Asn
  65                  70                  75                  80

 ggt ttt gtc cct ctc cct gca aat gcc ctc tga                          273
 Gly Phe Val Pro Leu Pro Ala Asn Ala Leu 
                  85                  90





      <210> 556
      <211> 606
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(606)

      <400> 556
  atg att tca gtt acc ctt agt ttc att ttg atg ttt gga aat tca atg      48
  Met Ile Ser Val Thr Leu Ser Phe Ile Leu Met Phe Gly Asn Ser Met
    1               5                  10                  15

 tac tta tct tct tct tat tct tca tct ttg tta atg acg tgg ata aaa       96
 Tyr Leu Ser Ser Ser Tyr Ser Ser Ser Leu Leu Met Thr Trp Ile Lys
              20                  25                  30

 ctg cat aaa gca aat gtt ttg tgt gct gac tta gag ctg gct aat act      144
 Leu His Lys Ala Asn Val Leu Cys Ala Asp Leu Glu Leu Ala Asn Thr
          35                  40                  45

 gat gag tac aat gtc ccc ttc gtg tct gca ggg att gat tcc agg aca      192
 Asp Glu Tyr Asn Val Pro Phe Val Ser Ala Gly Ile Asp Ser Arg Thr
      50                  55                  60

 ccc cca acc cct gtg gat act aaa atc tgc aga tgt tca agt ttc tta      240
 Pro Pro Thr Pro Val Asp Thr Lys Ile Cys Arg Cys Ser Ser Phe Leu
  65                  70                  75                  80

 tat aaa atg gca ata att cta aag aga aat gaa att caa aaa ctg gga      288
 Tyr Lys Met Ala Ile Ile Leu Lys Arg Asn Glu Ile Gln Lys Leu Gly
                  85                  90                  95

 gta tct aaa ctc aac ttt tgg gaa tcc aaa gac gtt tct gga aaa tcc      336
 Val Ser Lys Leu Asn Phe Trp Glu Ser Lys Asp Val Ser Gly Lys Ser
             100                 105                 110

 aaa aat tgg cag aag aca ctc aga aag agg gtc cag gga aat gct ctc      384
 Lys Asn Trp Gln Lys Thr Leu Arg Lys Arg Val Gln Gly Asn Ala Leu
         115                 120                 125

 cat gct gtg ggt ctg gta tct act att ccc tcc aag aag gct gcc cat      432
 His Ala Val Gly Leu Val Ser Thr Ile Pro Ser Lys Lys Ala Ala His
     130                 135                 140

 gca ggt agc agc agc agg gat cta aca gat gcc ctg cta gga cta ggc      480
 Ala Gly Ser Ser Ser Arg Asp Leu Thr Asp Ala Leu Leu Gly Leu Gly
 145                 150                 155                 160

 agc cca gga aag agc cct ctg ctc ttt acc gac ctc cta gcc cac aat      528
 Ser Pro Gly Lys Ser Pro Leu Leu Phe Thr Asp Leu Leu Ala His Asn
                 165                 170                 175

 cct ggt gtc tct caa cct cca cct cat ggc aac agg aca tgg gaa gta      576
 Pro Gly Val Ser Gln Pro Pro Pro His Gly Asn Arg Thr Trp Glu Val
             180                 185                 190

 cat tct tcc tac att ggt agc atg att tga                              606
 His Ser Ser Tyr Ile Gly Ser Met Ile 
         195                 200





      <210> 557
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 557
  atg gcc gca ctg gca atg gcc gca ctg gcg atg gcc aca ctg acg atg      48
  Met Ala Ala Leu Ala Met Ala Ala Leu Ala Met Ala Thr Leu Thr Met
    1               5                  10                  15

 gcc gca ctg atg atg gca ttg gtt cat gct gct cct gct gtc cac gcc       96
 Ala Ala Leu Met Met Ala Leu Val His Ala Ala Pro Ala Val His Ala
              20                  25                  30

 gct cct gcc atc cac cag ctg cca ggg ggc ctc ccc agg gcc atc cac      144
 Ala Pro Ala Ile His Gln Leu Pro Gly Gly Leu Pro Arg Ala Ile His
          35                  40                  45

 acc tcc atg tcc gtg tcc atc tcc agc tcg ttc tcc ccc aca tct gac      192
 Thr Ser Met Ser Val Ser Ile Ser Ser Ser Phe Ser Pro Thr Ser Asp
      50                  55                  60

 gcc cca tct gca gca ttg agg gtg cct cag tcc ttc tcc cgg aaa cca      240
 Ala Pro Ser Ala Ala Leu Arg Val Pro Gln Ser Phe Ser Arg Lys Pro
  65                  70                  75                  80

 aca ctt tgc ttg gct cct gga tac ccc atg ccc tgt gcc ctc cca ccc      288
 Thr Leu Cys Leu Ala Pro Gly Tyr Pro Met Pro Cys Ala Leu Pro Pro
                  85                  90                  95

 cca gac tcc tct gaa gga gga ttc aga gga atc ttc gcc tcc tct gaa      336
 Pro Asp Ser Ser Glu Gly Gly Phe Arg Gly Ile Phe Ala Ser Ser Glu
             100                 105                 110

 gga gga ttc aga gga atc ttc gcc tcc tct gaa gga gga ttc aga gga      384
 Gly Gly Phe Arg Gly Ile Phe Ala Ser Ser Glu Gly Gly Phe Arg Gly
         115                 120                 125

 atc ttc gcc tcc tct gaa gat tcc tcg tcc cag agc tca cct gaa cgt      432
 Ile Phe Ala Ser Ser Glu Asp Ser Ser Ser Gln Ser Ser Pro Glu Arg
     130                 135                 140

 ctt ctc tac acg act ttc ctg tgg tct tct ggg ggc cct gcc atc cgt      480
 Leu Leu Tyr Thr Thr Phe Leu Trp Ser Ser Gly Gly Pro Ala Ile Arg
 145                 150                 155                 160

 tca cca ttg aag gac gct tgt gtt gct tcc agc act tgg tga              522
 Ser Pro Leu Lys Asp Ala Cys Val Ala Ser Ser Thr Trp 
                 165                 170





      <210> 558
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 558
  atg ggg tct gct cct gct acc ttg acc ctt ccc ttt cct ctg ctt ctc      48
  Met Gly Ser Ala Pro Ala Thr Leu Thr Leu Pro Phe Pro Leu Leu Leu
    1               5                  10                  15

 tcc tca tca tca ttc cca aca aca tcc tct gcc aca cac aac aaa acg       96
 Ser Ser Ser Ser Phe Pro Thr Thr Ser Ser Ala Thr His Asn Lys Thr
              20                  25                  30

 ctt act gaa tat ccc tcc agg acg ctg ctg tct atc aga act agc agg      144
 Leu Thr Glu Tyr Pro Ser Arg Thr Leu Leu Ser Ile Arg Thr Ser Arg
          35                  40                  45

 aaa aac cat ggt ctt tgc aca atg gga act caa aat aaa gaa aag aaa      192
 Lys Asn His Gly Leu Cys Thr Met Gly Thr Gln Asn Lys Glu Lys Lys
      50                  55                  60

 gag aaa tac cta ggg atg ctt tac aca aac aac atg cct gag gct aac      240
 Glu Lys Tyr Leu Gly Met Leu Tyr Thr Asn Asn Met Pro Glu Ala Asn
  65                  70                  75                  80

 aga agc aca aac tgc atg tct ccc ggt gac ttg gac tgc act gac acc      288
 Arg Ser Thr Asn Cys Met Ser Pro Gly Asp Leu Asp Cys Thr Asp Thr
                  85                  90                  95

 agt tgg att tta ccc agc aga cca gat gca ggt ggg aga ttc ccc atc      336
 Ser Trp Ile Leu Pro Ser Arg Pro Asp Ala Gly Gly Arg Phe Pro Ile
             100                 105                 110

 cgc acc cct ccc tgt gtg ctt gtg gtt cat aag cca agc cga cac tgc      384
 Arg Thr Pro Pro Cys Val Leu Val Val His Lys Pro Ser Arg His Cys
         115                 120                 125

 agg gag ctc aaa agc cat gga ttc gtt cat tcc gtg gat acc gat gcc      432
 Arg Glu Leu Lys Ser His Gly Phe Val His Ser Val Asp Thr Asp Ala
     130                 135                 140

 cac cct gtg cca ggc act gtc gta gat att gag aaa aca gca aac ata      480
 His Pro Val Pro Gly Thr Val Val Asp Ile Glu Lys Thr Ala Asn Ile
 145                 150                 155                 160

 caa act acc tcc tgc tat tgt gct cat tgt cat gga ggg tga              522
 Gln Thr Thr Ser Cys Tyr Cys Ala His Cys His Gly Gly 
                 165                 170





      <210> 559
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 559
  atg cgg gtg ggg gcg tgc gcg ctg tgc cct ctg ggc tgc cag tct ctc      48
  Met Arg Val Gly Ala Cys Ala Leu Cys Pro Leu Gly Cys Gln Ser Leu
    1               5                  10                  15

 ctg ggc cac cca gtg cag gga tgg agc ggt ggg ggc ctt ctg aag gag       96
 Leu Gly His Pro Val Gln Gly Trp Ser Gly Gly Gly Leu Leu Lys Glu
              20                  25                  30

 gtg gcc ctg ctg tct cct gct cta ttc ctg acc ctc aca gac tgg cca      144
 Val Ala Leu Leu Ser Pro Ala Leu Phe Leu Thr Leu Thr Asp Trp Pro
          35                  40                  45

 aac tcg acg cag aca aac tcg atg tgt ggc agg gtc cca gtt tat aaa      192
 Asn Ser Thr Gln Thr Asn Ser Met Cys Gly Arg Val Pro Val Tyr Lys
      50                  55                  60

 aag gaa atg gct acc agc agg gat act gtc aaa acc acc gcc atc cac      240
 Lys Glu Met Ala Thr Ser Arg Asp Thr Val Lys Thr Thr Ala Ile His
  65                  70                  75                  80

 gtc agc tga                                                          249
 Val Ser 






      <210> 560
      <211> 795
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(795)

      <400> 560
  atg ccc cat tcc ctg caa aca ctg ata ttg ttt ggt ctc tcc ttg gca      48
  Met Pro His Ser Leu Gln Thr Leu Ile Leu Phe Gly Leu Ser Leu Ala
    1               5                  10                  15

 aac agg aat ttt atc att gga aca tct gat gcc gcg gtg tac cac tta       96
 Asn Arg Asn Phe Ile Ile Gly Thr Ser Asp Ala Ala Val Tyr His Leu
              20                  25                  30

 aca aca gat ggg acc aaa ctt gag aag tta ttt gta gag ccc aag gat      144
 Thr Thr Asp Gly Thr Lys Leu Glu Lys Leu Phe Val Glu Pro Lys Asp
          35                  40                  45

 gcc att tgt gcc atc tcc tgc cac cca tat caa ccc ctc att gcc atc      192
 Ala Ile Cys Ala Ile Ser Cys His Pro Tyr Gln Pro Leu Ile Ala Ile
      50                  55                  60

 ggg agc atc tgt ggg atg atc aaa gtg tgg aat tat gaa aac aaa caa      240
 Gly Ser Ile Cys Gly Met Ile Lys Val Trp Asn Tyr Glu Asn Lys Gln
  65                  70                  75                  80

 tat ctt ttc agc agg gtt ttt gag aag ggg ctt gga gtc cag agt ctg      288
 Tyr Leu Phe Ser Arg Val Phe Glu Lys Gly Leu Gly Val Gln Ser Leu
                  85                  90                  95

 acc tac aac ccc gaa gga gcc ctt ctt gga gct ggc ttt aca gag ggg      336
 Thr Tyr Asn Pro Glu Gly Ala Leu Leu Gly Ala Gly Phe Thr Glu Gly
             100                 105                 110

 aca gtt tac att ctt gat gca atg tct tta gaa aat gaa agc cca gag      384
 Thr Val Tyr Ile Leu Asp Ala Met Ser Leu Glu Asn Glu Ser Pro Glu
         115                 120                 125

 cct ttc aaa tat tcc aga acc agt gtg act cat ata agc ttt tcc cat      432
 Pro Phe Lys Tyr Ser Arg Thr Ser Val Thr His Ile Ser Phe Ser His
     130                 135                 140

 gac tcc cag tat atg gca act gct gat aga agt ttt act gtg gct gtt      480
 Asp Ser Gln Tyr Met Ala Thr Ala Asp Arg Ser Phe Thr Val Ala Val
 145                 150                 155                 160

 tac atg ctg gtg gtc aga aat gga cag agg gtc tgg gag tac tta gca      528
 Tyr Met Leu Val Val Arg Asn Gly Gln Arg Val Trp Glu Tyr Leu Ala
                 165                 170                 175

 aga ctt cgc tct cat cgc aaa agc att cga agt ctc ctg ttt ggg gtt      576
 Arg Leu Arg Ser His Arg Lys Ser Ile Arg Ser Leu Leu Phe Gly Val
             180                 185                 190

 tac ctg gac agc aat gag cct aga ctg ctg agc ctt ggg aca gac agg      624
 Tyr Leu Asp Ser Asn Glu Pro Arg Leu Leu Ser Leu Gly Thr Asp Arg
         195                 200                 205

 ctc ttg gtg agc tgt tta gtt ttc gtt gac ctg gtc gcc aag act gtg      672
 Leu Leu Val Ser Cys Leu Val Phe Val Asp Leu Val Ala Lys Thr Val
     210                 215                 220

 tct cac tct tgt gac atc cct ggc atc ttg cat aga gcc agg ccc aca      720
 Ser His Ser Cys Asp Ile Pro Gly Ile Leu His Arg Ala Arg Pro Thr
 225                 230                 235                 240

 gta cgt gtg ttt gtt gga gaa aat gaa tgc aca gtg aag gat cac aaa      768
 Val Arg Val Phe Val Gly Glu Asn Glu Cys Thr Val Lys Asp His Lys
                 245                 250                 255

 cct ctc cag gtt ggc att ttg cct taa                                  795
 Pro Leu Gln Val Gly Ile Leu Pro 
             260





      <210> 561
      <211> 1116
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1116)

      <400> 561
  atg gcc atg aac ttg ttg gta ctg atg tca acc ttg gtt gcc ggc agc      48
  Met Ala Met Asn Leu Leu Val Leu Met Ser Thr Leu Val Ala Gly Ser
    1               5                  10                  15

 tct gcg ggg gag gtt cct gat ctc caa cat ccc atg cag aga ggc tcc       96
 Ser Ala Gly Glu Val Pro Asp Leu Gln His Pro Met Gln Arg Gly Ser
              20                  25                  30

 act gcc tgc att aat cat ccc agg ggc cat gaa gag cgc ccc caa cag      144
 Thr Ala Cys Ile Asn His Pro Arg Gly His Glu Glu Arg Pro Gln Gln
          35                  40                  45

 tct ggg ggg agc tca ttc agc tcc gga ttt aca gca gga gat ggg gtc      192
 Ser Gly Gly Ser Ser Phe Ser Ser Gly Phe Thr Ala Gly Asp Gly Val
      50                  55                  60

 tcc ggt gcc acc cac aga cgc ttc aca ccc acc aag tgt cac ccg atg      240
 Ser Gly Ala Thr His Arg Arg Phe Thr Pro Thr Lys Cys His Pro Met
  65                  70                  75                  80

 aga aaa ttg agg gag aaa tta agt aac ttg ccc aag gtc acc tac cta      288
 Arg Lys Leu Arg Glu Lys Leu Ser Asn Leu Pro Lys Val Thr Tyr Leu
                  85                  90                  95

 gca atg cac aag tcc tgt ctc cac acc agg tac tgg gat cct cag agg      336
 Ala Met His Lys Ser Cys Leu His Thr Arg Tyr Trp Asp Pro Gln Arg
             100                 105                 110

 ctt acg aag ctc ggc ctt cac tta agg tgt cta ctc tcc aag acc aag      384
 Leu Thr Lys Leu Gly Leu His Leu Arg Cys Leu Leu Ser Lys Thr Lys
         115                 120                 125

 ctg ggg aag aca gca tca gat ggt ttc ccc tcc ggc gag ccc gaa acg      432
 Leu Gly Lys Thr Ala Ser Asp Gly Phe Pro Ser Gly Glu Pro Glu Thr
     130                 135                 140

 gta cag acc cag ggc ccc gtc cga cgc ccg acc cct cgc ccc agt gcc      480
 Val Gln Thr Gln Gly Pro Val Arg Arg Pro Thr Pro Arg Pro Ser Ala
 145                 150                 155                 160

 ccc gaa cgt ggc cgc cac tct gct ttg aac agc gaa gga act cga gac      528
 Pro Glu Arg Gly Arg His Ser Ala Leu Asn Ser Glu Gly Thr Arg Asp
                 165                 170                 175

 aga gcc gag ctg ggc tgc ggc cag ccc acg gcc agt cgg cgg aag gtc      576
 Arg Ala Glu Leu Gly Cys Gly Gln Pro Thr Ala Ser Arg Arg Lys Val
             180                 185                 190

 ggg ggc ccc agg ctc ttg cgc ggc ccc aca gac cct tgc gtc aga aga      624
 Gly Gly Pro Arg Leu Leu Arg Gly Pro Thr Asp Pro Cys Val Arg Arg
         195                 200                 205

 gtg gcc ccc cgc gcc atg ggc tct gcg gcc agg agg cca cgt gcg acg      672
 Val Ala Pro Arg Ala Met Gly Ser Ala Ala Arg Arg Pro Arg Ala Thr
     210                 215                 220

 tcg ctc agg ccg gaa cac gtg gct cca gca gaa gcc aca tct gga ttc      720
 Ser Leu Arg Pro Glu His Val Ala Pro Ala Glu Ala Thr Ser Gly Phe
 225                 230                 235                 240

 tac acg tgc tgg gct gcg ggc gag gtt ctt cca cac cac agg cgt ctt      768
 Tyr Thr Cys Trp Ala Ala Gly Glu Val Leu Pro His His Arg Arg Leu
                 245                 250                 255

 ctt gcc acc cag gag acc tgg gcc ggc agc ttc cct gca gtg cgg ggc      816
 Leu Ala Thr Gln Glu Thr Trp Ala Gly Ser Phe Pro Ala Val Arg Gly
             260                 265                 270

 cca cgg gct ccc cgc agt ggg gag tgc gag aaa cgc aac tgc gac ctc      864
 Pro Arg Ala Pro Arg Ser Gly Glu Cys Glu Lys Arg Asn Cys Asp Leu
         275                 280                 285

 gcc gcg cac tcc gct tcc gcc att ggc tca gga tcc ctg cgt gga gcg      912
 Ala Ala His Ser Ala Ser Ala Ile Gly Ser Gly Ser Leu Arg Gly Ala
     290                 295                 300

 agg gcg cca cgc tgc gac tgc agc agg gac ggc acg tcc cag ggg aga      960
 Arg Ala Pro Arg Cys Asp Cys Ser Arg Asp Gly Thr Ser Gln Gly Arg
 305                 310                 315                 320

 gcg cgg gaa ata tgg tgc gtg ccc acc cct aac cca cct ctg gag gcc     1008
 Ala Arg Glu Ile Trp Cys Val Pro Thr Pro Asn Pro Pro Leu Glu Ala
                 325                 330                 335

 tca ctg acc aca cgc ccc cag gcc tca aga ctt ccc gtt tct gag gtt     1056
 Ser Leu Thr Thr Arg Pro Gln Ala Ser Arg Leu Pro Val Ser Glu Val
             340                 345                 350

 gtg ccc aac aga aat gcc ctc aaa gtg ctc agc aag gct cca ttc atc     1104
 Val Pro Asn Arg Asn Ala Leu Lys Val Leu Ser Lys Ala Pro Phe Ile
         355                 360                 365

 cat gac cta tga                                                     1116
 His Asp Leu 
     370





      <210> 562
      <211> 477
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(477)

      <400> 562
  atg cta gca tgg ata ata aaa ctc att ggc tcc ttt tta caa gtg gtg      48
  Met Leu Ala Trp Ile Ile Lys Leu Ile Gly Ser Phe Leu Gln Val Val
    1               5                  10                  15

 agc agc cag acc ttt ttg cca gtt aca gaa gta ttg gaa aag cta acc       96
 Ser Ser Gln Thr Phe Leu Pro Val Thr Glu Val Leu Glu Lys Leu Thr
              20                  25                  30

 aat gtc agc agc aag caa gcc aat tgc acc aaa tat acc aaa cat aca      144
 Asn Val Ser Ser Lys Gln Ala Asn Cys Thr Lys Tyr Thr Lys His Thr
          35                  40                  45

 gtc cag tat aac ctg agc cac tca gac tct gat tct cag aaa ctg aca      192
 Val Gln Tyr Asn Leu Ser His Ser Asp Ser Asp Ser Gln Lys Leu Thr
      50                  55                  60

 ttg gaa ctc aga gat ggc aac aac aat gtc aag aag gag gcg gcg gca      240
 Leu Glu Leu Arg Asp Gly Asn Asn Asn Val Lys Lys Glu Ala Ala Ala
  65                  70                  75                  80

 gga agt gca gtc tac agt aag gga aag ccg ccg gag ctg gag aca ggc      288
 Gly Ser Ala Val Tyr Ser Lys Gly Lys Pro Pro Glu Leu Glu Thr Gly
                  85                  90                  95

 tgg aaa gag cag gta aca gcc cac aag gag cgg ggg ccc tgg ctg tca      336
 Trp Lys Glu Gln Val Thr Ala His Lys Glu Arg Gly Pro Trp Leu Ser
             100                 105                 110

 gac tca act tgc agg acc atc aag tgc agg aaa aaa gag gtc aac tcg      384
 Asp Ser Thr Cys Arg Thr Ile Lys Cys Arg Lys Lys Glu Val Asn Ser
         115                 120                 125

 gag gag cca ggg att cag ccc act ctg gac aac act cag agc cat ggc      432
 Glu Glu Pro Gly Ile Gln Pro Thr Leu Asp Asn Thr Gln Ser His Gly
     130                 135                 140

 acc tac ctg tat gaa aaa aaa ttg tta agc agc tgc cac tcc tag          477
 Thr Tyr Leu Tyr Glu Lys Lys Leu Leu Ser Ser Cys His Ser 
 145                 150                 155





      <210> 563
      <211> 453
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(453)

      <400> 563
  atg gac ttc agg aag tgg gcg tac acg gtg act aag agc atg gca ttt      48
  Met Asp Phe Arg Lys Trp Ala Tyr Thr Val Thr Lys Ser Met Ala Phe
    1               5                  10                  15

 gct ctt cct ctg ttc atc tct ttc ctt ctg tct ttc ctg aat gat tta       96
 Ala Leu Pro Leu Phe Ile Ser Phe Leu Leu Ser Phe Leu Asn Asp Leu
              20                  25                  30

 gag gga aaa agc aag gac agc caa ggt gaa ctc aag gcc atg aag cgt      144
 Glu Gly Lys Ser Lys Asp Ser Gln Gly Glu Leu Lys Ala Met Lys Arg
          35                  40                  45

 gtg gct gaa ggg agt gaa gaa cag gaa ggc cag gtg gac atc agg gcc      192
 Val Ala Glu Gly Ser Glu Glu Gln Glu Gly Gln Val Asp Ile Arg Ala
      50                  55                  60

 cta gta gac caa cag gcc cac agt gcc ctg gaa gct gag gct cat cta      240
 Leu Val Asp Gln Gln Ala His Ser Ala Leu Glu Ala Glu Ala His Leu
  65                  70                  75                  80

 tgc caa gca gca act tcg ggc act atc ctt cgg cca cgg ctg cag gac      288
 Cys Gln Ala Ala Thr Ser Gly Thr Ile Leu Arg Pro Arg Leu Gln Asp
                  85                  90                  95

 ctg ggc gga ctg gat cta gca ggc atc cag gaa atg ttt gtg gaa tca      336
 Leu Gly Gly Leu Asp Leu Ala Gly Ile Gln Glu Met Phe Val Glu Ser
             100                 105                 110

 atg aat gaa aga atg aac acc atg aga aag ttc tcc aac aga tac tta      384
 Met Asn Glu Arg Met Asn Thr Met Arg Lys Phe Ser Asn Arg Tyr Leu
         115                 120                 125

 ctg aac gag cat agg cat cag agc gac tat ggt ctc cca cct acc cgg      432
 Leu Asn Glu His Arg His Gln Ser Asp Tyr Gly Leu Pro Pro Thr Arg
     130                 135                 140

 cca cgt tca tca act ctc taa                                          453
 Pro Arg Ser Ser Thr Leu 
 145                 150





      <210> 564
      <211> 258
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(258)

      <400> 564
  atg tgg gat cct cga gct aag atg agg gca tcc ctc acg ttc aca ccc      48
  Met Trp Asp Pro Arg Ala Lys Met Arg Ala Ser Leu Thr Phe Thr Pro
    1               5                  10                  15

 ctg gtg gca tct gcc agc cct gtt ctg ggg aca agg cgg gct ttc gtg       96
 Leu Val Ala Ser Ala Ser Pro Val Leu Gly Thr Arg Arg Ala Phe Val
              20                  25                  30

 gga gcc gtg ctc agc ctg cca gga agc caa gcc cta cag tgc aga gga      144
 Gly Ala Val Leu Ser Leu Pro Gly Ser Gln Ala Leu Gln Cys Arg Gly
          35                  40                  45

 aac aga att tca acg gga agc tgg ttt gct tca tac cat tgg gat ctg      192
 Asn Arg Ile Ser Thr Gly Ser Trp Phe Ala Ser Tyr His Trp Asp Leu
      50                  55                  60

 ctg atc cag tct gta ctt gaa tat gag cag agg atc tac aag aat gct      240
 Leu Ile Gln Ser Val Leu Glu Tyr Glu Gln Arg Ile Tyr Lys Asn Ala
  65                  70                  75                  80

 gac agg gaa ccg tgt taa                                              258
 Asp Arg Glu Pro Cys 
                  85





      <210> 565
      <211> 978
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(978)

      <400> 565
  atg cac gca gca tcg gcc cta cac ctg ctt cca ctg gca ctt cgt gaa      48
  Met His Ala Ala Ser Ala Leu His Leu Leu Pro Leu Ala Leu Arg Glu
    1               5                  10                  15

 cca gcg gcg cgc cgg tcc atc cgc cgt cgg gac ggc acc ttc aat tac       96
 Pro Ala Ala Arg Arg Ser Ile Arg Arg Arg Asp Gly Thr Phe Asn Tyr
              20                  25                  30

 agc cct gac gtc tac tgc acc aag tac gac gag gct aca ggc cct ctg      144
 Ser Pro Asp Val Tyr Cys Thr Lys Tyr Asp Glu Ala Thr Gly Pro Leu
          35                  40                  45

 ccc gga ggg cga cga gga gct tca ggc cat gga ggc ttg cag aat ggc      192
 Pro Gly Gly Arg Arg Gly Ala Ser Gly His Gly Gly Leu Gln Asn Gly
      50                  55                  60

 cag acc acg gta gag ggg agc ata gag ggc cag tcg gct ggg gct gcg      240
 Gln Thr Thr Val Glu Gly Ser Ile Glu Gly Gln Ser Ala Gly Ala Ala
  65                  70                  75                  80

 agc cat gcc atg ata gaa aag atc ctc agc gag gag cct cgg tgg caa      288
 Ser His Ala Met Ile Glu Lys Ile Leu Ser Glu Glu Pro Arg Trp Gln
                  85                  90                  95

 gag act gct tat gtg ctg ggg aac tat aag acg gag cct tgc aag aag      336
 Glu Thr Ala Tyr Val Leu Gly Asn Tyr Lys Thr Glu Pro Cys Lys Lys
             100                 105                 110

 ccc ccg cgg ctg tgc cgc caa ggc tat gcc tgt ccc tac tac cac aac      384
 Pro Pro Arg Leu Cys Arg Gln Gly Tyr Ala Cys Pro Tyr Tyr His Asn
         115                 120                 125

 agc aag gac cgg ggg cgg agc ccc cgg aag cac aaa tac agg tcg tct      432
 Ser Lys Asp Arg Gly Arg Ser Pro Arg Lys His Lys Tyr Arg Ser Ser
     130                 135                 140

 cca tgt cca aac gtc aag cac ggg gat gag tgg gga gac cct ggc aag      480
 Pro Cys Pro Asn Val Lys His Gly Asp Glu Trp Gly Asp Pro Gly Lys
 145                 150                 155                 160

 tgt gag aac gga gac gcc tgc cag tac tgc cac acc cgc acc gag cag      528
 Cys Glu Asn Gly Asp Ala Cys Gln Tyr Cys His Thr Arg Thr Glu Gln
                 165                 170                 175

 cag ttc cac ccc gag atc tac aag tcc acc aag tgc aac gac atg cag      576
 Gln Phe His Pro Glu Ile Tyr Lys Ser Thr Lys Cys Asn Asp Met Gln
             180                 185                 190

 cag tcg ggc agc tgt ccc cga gga ccc ttc tgc gcc ttt gcc cac gta      624
 Gln Ser Gly Ser Cys Pro Arg Gly Pro Phe Cys Ala Phe Ala His Val
         195                 200                 205

 gaa cag cca ccc ctg agt gac gac ctg cag cct tcc tca gct gtg tcc      672
 Glu Gln Pro Pro Leu Ser Asp Asp Leu Gln Pro Ser Ser Ala Val Ser
     210                 215                 220

 agc ccc acc cag cca ggt cct gtc ctg tac atg cca tct gcc gcc gga      720
 Ser Pro Thr Gln Pro Gly Pro Val Leu Tyr Met Pro Ser Ala Ala Gly
 225                 230                 235                 240

 gac tcg gtg cct gtg agc ccc tcc agc ccg cat gcc cct gac ctc agt      768
 Asp Ser Val Pro Val Ser Pro Ser Ser Pro His Ala Pro Asp Leu Ser
                 245                 250                 255

 gcc ctc ctc tgt aga aac agc agc cta ggc agc ccg tct aac ctc tgc      816
 Ala Leu Leu Cys Arg Asn Ser Ser Leu Gly Ser Pro Ser Asn Leu Cys
             260                 265                 270

 ggc tcc cca ccg ggc tcc atc agg aag ccc cca aac ctg gag ggc atc      864
 Gly Ser Pro Pro Gly Ser Ile Arg Lys Pro Pro Asn Leu Glu Gly Ile
         275                 280                 285

 gtc ttc cct ggg gag tct ggc ctg gcc cct ggc agc tat aag aag gct      912
 Val Phe Pro Gly Glu Ser Gly Leu Ala Pro Gly Ser Tyr Lys Lys Ala
     290                 295                 300

 ccc ggc ttc gag agg gaa gac cag gtg gga gcc gag tac ctg aaa aat      960
 Pro Gly Phe Glu Arg Glu Asp Gln Val Gly Ala Glu Tyr Leu Lys Asn
 305                 310                 315                 320

 ttc aaa tgc cag gac tga                                              978
 Phe Lys Cys Gln Asp 
                 325





      <210> 566
      <211> 273
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(273)

      <400> 566
  atg cca acc tgg ggg gcg ctc cgg ttg ggg ggt gtg ccc tct ctg gtt      48
  Met Pro Thr Trp Gly Ala Leu Arg Leu Gly Gly Val Pro Ser Leu Val
    1               5                  10                  15

 acc ccg ctc tcg ctg cca ctc ata ggc ctg ctg ccc agc act tat gtc       96
 Thr Pro Leu Ser Leu Pro Leu Ile Gly Leu Leu Pro Ser Thr Tyr Val
              20                  25                  30

 aag atg ctg ctc tca gca cgt gac atg cta aca ctg cag act tca gga      144
 Lys Met Leu Leu Ser Ala Arg Asp Met Leu Thr Leu Gln Thr Ser Gly
          35                  40                  45

 gaa ctg gaa ttt gaa ccc aga gcc ttc ttc acc acc atc tcc gtt gtt      192
 Glu Leu Glu Phe Glu Pro Arg Ala Phe Phe Thr Thr Ile Ser Val Val
      50                  55                  60

 tct gga agc acc ctc cag gca ggc cag cca gca tca cgg ggc ctc ccc      240
 Ser Gly Ser Thr Leu Gln Ala Gly Gln Pro Ala Ser Arg Gly Leu Pro
  65                  70                  75                  80

 tgg ggc tgg aac gtc tgc agg atg ccc ctt tga                          273
 Trp Gly Trp Asn Val Cys Arg Met Pro Leu 
                  85                  90





      <210> 567
      <211> 156
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(156)

      <400> 567
  atg gaa cag tta tgt atc ttg act gta gta gta gcc aat gct acc ttc      48
  Met Glu Gln Leu Cys Ile Leu Thr Val Val Val Ala Asn Ala Thr Phe
    1               5                  10                  15

 acc tgc atc ttc tca tca aag cct acc atg gat aca cag tta gct tct       96
 Thr Cys Ile Phe Ser Ser Lys Pro Thr Met Asp Thr Gln Leu Ala Ser
              20                  25                  30

 ttc ctc tta gcc agt gat ctg ccc atg atg atc cct gat agc aaa agg      144
 Phe Leu Leu Ala Ser Asp Leu Pro Met Met Ile Pro Asp Ser Lys Arg
          35                  40                  45

 ttt cct ttc tga                                                      156
 Phe Pro Phe 
      50





      <210> 568
      <211> 429
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(429)

      <400> 568
  atg gtg ctt att tct tgt tat tct ttg gct ttt gaa agc ctt att gtg      48
  Met Val Leu Ile Ser Cys Tyr Ser Leu Ala Phe Glu Ser Leu Ile Val
    1               5                  10                  15

 ctg aag aag gca ata ata gaa gca gca gta aga ata gca gta cag cca       96
 Leu Lys Lys Ala Ile Ile Glu Ala Ala Val Arg Ile Ala Val Gln Pro
              20                  25                  30

 agg cag ttc aat ctt agt gat aca gat aaa att gag tac agt gaa atg      144
 Arg Gln Phe Asn Leu Ser Asp Thr Asp Lys Ile Glu Tyr Ser Glu Met
          35                  40                  45

 aga aag aaa ctg gaa gtc act ggg tgt caa tcc tca tct ctg ccc cta      192
 Arg Lys Lys Leu Glu Val Thr Gly Cys Gln Ser Ser Ser Leu Pro Leu
      50                  55                  60

 act ggc tgt gta acc ttg agc aaa cca tct acc tca gtc tgg gac cac      240
 Thr Gly Cys Val Thr Leu Ser Lys Pro Ser Thr Ser Val Trp Asp His
  65                  70                  75                  80

 act aga tca gca ggc ctt aac ctc tta gag atg atg ggc ctt ttt gag      288
 Thr Arg Ser Ala Gly Leu Asn Leu Leu Glu Met Met Gly Leu Phe Glu
                  85                  90                  95

 aat gag aac gag gaa ccc aat tcc cct cag aaa gac atg cta aat gat      336
 Asn Glu Asn Glu Glu Pro Asn Ser Pro Gln Lys Asp Met Leu Asn Asp
             100                 105                 110

 aca cac aat gtc aaa cca cca aca ttc ctc atc cag act tat tct cag      384
 Thr His Asn Val Lys Pro Pro Thr Phe Leu Ile Gln Thr Tyr Ser Gln
         115                 120                 125

 cag ctg acc tat ttt gca gac aaa aca gca aca atc caa aga taa          429
 Gln Leu Thr Tyr Phe Ala Asp Lys Thr Ala Thr Ile Gln Arg 
     130                 135                 140





      <210> 569
      <211> 1245
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1245)

      <400> 569
  atg aga ggt tct aag agg cag gct agt ggc ttg tac tat atc ata gcc      48
  Met Arg Gly Ser Lys Arg Gln Ala Ser Gly Leu Tyr Tyr Ile Ile Ala
    1               5                  10                  15

 tgc ctt tgc tgg cat gtg gcg att agg cct ggt gga act gcc atc aat       96
 Cys Leu Cys Trp His Val Ala Ile Arg Pro Gly Gly Thr Ala Ile Asn
              20                  25                  30

 aaa cca ggt gtg atc agg gtg aga aac agg gaa gaa gga aat gtg ggg      144
 Lys Pro Gly Val Ile Arg Val Arg Asn Arg Glu Glu Gly Asn Val Gly
          35                  40                  45

 aaa tgg ggt gaa cgt cag gtg gat cag aga gat gca gtc atg agg gtc      192
 Lys Trp Gly Glu Arg Gln Val Asp Gln Arg Asp Ala Val Met Arg Val
      50                  55                  60

 aag tgt ggt atc agg aat aat gtg aga ggc cac att gaa gtc cga gcc      240
 Lys Cys Gly Ile Arg Asn Asn Val Arg Gly His Ile Glu Val Arg Ala
  65                  70                  75                  80

 agg aac aat ggt aat tgt ggg aga ctc aac aaa gag gct tcc gag gca      288
 Arg Asn Asn Gly Asn Cys Gly Arg Leu Asn Lys Glu Ala Ser Glu Ala
                  85                  90                  95

 atc ggg cag tgt cag tct tca gcc gct aag cca aga aga tct ggg aag      336
 Ile Gly Gln Cys Gln Ser Ser Ala Ala Lys Pro Arg Arg Ser Gly Lys
             100                 105                 110

 gag tca gca gag agc ctt ggg cca gag ttc cag ggg ctc tgg gag tgg      384
 Glu Ser Ala Glu Ser Leu Gly Pro Glu Phe Gln Gly Leu Trp Glu Trp
         115                 120                 125

 ctg cca ggc aca aga gca aat cag aga atg ggg cct gaa gtg aac ccc      432
 Leu Pro Gly Thr Arg Ala Asn Gln Arg Met Gly Pro Glu Val Asn Pro
     130                 135                 140

 cag aaa act gta gca gcc cta cag aag agg aat ctg att att gaa aga      480
 Gln Lys Thr Val Ala Ala Leu Gln Lys Arg Asn Leu Ile Ile Glu Arg
 145                 150                 155                 160

 aaa aca aac aag cag aaa gtg aca aca gcg tca tca aca aca aca aca      528
 Lys Thr Asn Lys Gln Lys Val Thr Thr Ala Ser Ser Thr Thr Thr Thr
                 165                 170                 175

 aca aca aca ata aag gcc ccc aca aaa gcc cca tcc aag ggt cag caa      576
 Thr Thr Thr Ile Lys Ala Pro Thr Lys Ala Pro Ser Lys Gly Gln Gln
             180                 185                 190

 cct caa aga cca aaa cta gac aaa ctc acg aag atg aga aag aat caa      624
 Pro Gln Arg Pro Lys Leu Asp Lys Leu Thr Lys Met Arg Lys Asn Gln
         195                 200                 205

 caa aaa atg ctg aaa acc caa aag gcc aga gtg cct ctt ctc ctc caa      672
 Gln Lys Met Leu Lys Thr Gln Lys Ala Arg Val Pro Leu Leu Leu Gln
     210                 215                 220

 atg att aca gga tta cag tgt ctg tcc atc aag gat gca gaa ctg gac      720
 Met Ile Thr Gly Leu Gln Cys Leu Ser Ile Lys Asp Ala Glu Leu Asp
 225                 230                 235                 240

 aga gga tca gat gga cga ctt gac aga aac aga tca gca aga cag aaa      768
 Arg Gly Ser Asp Gly Arg Leu Asp Arg Asn Arg Ser Ala Arg Gln Lys
                 245                 250                 255

 att aac aag gtt att cag gac ttg tac tca act ctg gat caa gtg gac      816
 Ile Asn Lys Val Ile Gln Asp Leu Tyr Ser Thr Leu Asp Gln Val Asp
             260                 265                 270

 cta gta gac ttc tac aga act ctt tat gcc aaa tca aca gag tat aca      864
 Leu Val Asp Phe Tyr Arg Thr Leu Tyr Ala Lys Ser Thr Glu Tyr Thr
         275                 280                 285

 ttc ttc tca ggg cca cat ggc act tat tct aaa att gac cac ata att      912
 Phe Phe Ser Gly Pro His Gly Thr Tyr Ser Lys Ile Asp His Ile Ile
     290                 295                 300

 ggg agt aaa aca ctc ctc agc aaa tgc aaa gga act gaa ata ata aca      960
 Gly Ser Lys Thr Leu Leu Ser Lys Cys Lys Gly Thr Glu Ile Ile Thr
 305                 310                 315                 320

 aac agc ccc tca gaa tac agt gca atc aaa tta gaa ctc agg gtt acg     1008
 Asn Ser Pro Ser Glu Tyr Ser Ala Ile Lys Leu Glu Leu Arg Val Thr
                 325                 330                 335

 aaa ctc act caa aac cac aca att tca tgg aaa ttg aac aac ctg atc     1056
 Lys Leu Thr Gln Asn His Thr Ile Ser Trp Lys Leu Asn Asn Leu Ile
             340                 345                 350

 ctg aat gac tcc tgg gta aat aat gaa act aaa gcc gaa atc aag aag     1104
 Leu Asn Asp Ser Trp Val Asn Asn Glu Thr Lys Ala Glu Ile Lys Lys
         355                 360                 365

 gtc ttt gaa acc aat ggg aac aaa gag aca aca tac cag aat ctc tgg     1152
 Val Phe Glu Thr Asn Gly Asn Lys Glu Thr Thr Tyr Gln Asn Leu Trp
     370                 375                 380

 gac aca gat aaa gca gtg tta aga ggg aaa ttt ata gca cta aat acc     1200
 Asp Thr Asp Lys Ala Val Leu Arg Gly Lys Phe Ile Ala Leu Asn Thr
 385                 390                 395                 400

 cac atc aga aag ctg aaa aaa tct caa att gac aca cta cca tga         1245
 His Ile Arg Lys Leu Lys Lys Ser Gln Ile Asp Thr Leu Pro 
                 405                 410





      <210> 570
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 570
  atg atc ttg atg act gct cca gtg act tcc tct atc tcc tgc acc act      48
  Met Ile Leu Met Thr Ala Pro Val Thr Ser Ser Ile Ser Cys Thr Thr
    1               5                  10                  15

 gag att ctg atg ctg att tct att ctg ttg ctg tct ctg atg caa gag       96
 Glu Ile Leu Met Leu Ile Ser Ile Leu Leu Leu Ser Leu Met Gln Glu
              20                  25                  30

 gac cag gat aac acg gtg gca ttg ggg gcc gaa cat gga cag gct ttg      144
 Asp Gln Asp Asn Thr Val Ala Leu Gly Ala Glu His Gly Gln Ala Leu
          35                  40                  45

 aac gca gaa tct tcc aaa ttg gct ttc gtt ttc agt tgc tgg ttt cag      192
 Asn Ala Glu Ser Ser Lys Leu Ala Phe Val Phe Ser Cys Trp Phe Gln
      50                  55                  60

 gcg gag gaa agt cta tgg aat agg act gca cag gct ctg ttg ggt aaa      240
 Ala Glu Glu Ser Leu Trp Asn Arg Thr Ala Gln Ala Leu Leu Gly Lys
  65                  70                  75                  80

 gct ggg tac ggc cat ctg ctt agg tgg ggt gcc tat ggg gac agc tct      288
 Ala Gly Tyr Gly His Leu Leu Arg Trp Gly Ala Tyr Gly Asp Ser Ser
                  85                  90                  95

 aac agg agg act gcc aat gac agt gtg aag tat ttt gtg ttg ttc ctc      336
 Asn Arg Arg Thr Ala Asn Asp Ser Val Lys Tyr Phe Val Leu Phe Leu
             100                 105                 110

 agc ctt aaa cat atg cag tta ccc tgc tgt gac aat ggt ttt aaa cag      384
 Ser Leu Lys His Met Gln Leu Pro Cys Cys Asp Asn Gly Phe Lys Gln
         115                 120                 125

 gag tct ttt tga                                                      396
 Glu Ser Phe 
     130





      <210> 571
      <211> 726
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(726)

      <400> 571
  atg gga cag gta tgg tgt ctg gtt tgt atc acc ttg gaa ctt ttt cac      48
  Met Gly Gln Val Trp Cys Leu Val Cys Ile Thr Leu Glu Leu Phe His
    1               5                  10                  15

 act gat aat gag gag gaa caa gag tat agc gaa gta aca aaa gag gtt       96
 Thr Asp Asn Glu Glu Glu Gln Glu Tyr Ser Glu Val Thr Lys Glu Val
              20                  25                  30

 aca gag cat gtt tat tta cca gct aaa gct aaa gcg gca aag gaa gga      144
 Thr Glu His Val Tyr Leu Pro Ala Lys Ala Lys Ala Ala Lys Glu Gly
          35                  40                  45

 gag gtt cat ccc tac cct tct gca ccc cct cct tat tat ttt gaa gac      192
 Glu Val His Pro Tyr Pro Ser Ala Pro Pro Pro Tyr Tyr Phe Glu Asp
      50                  55                  60

 aaa gac cct cca gat ctt tct ttt ctg gag gac act ggg caa aaa gta      240
 Lys Asp Pro Pro Asp Leu Ser Phe Leu Glu Asp Thr Gly Gln Lys Val
  65                  70                  75                  80

 gtt gcc cca gca gga att cag caa gct aga cga gag ggt gat tta gag      288
 Val Ala Pro Ala Gly Ile Gln Gln Ala Arg Arg Glu Gly Asp Leu Glu
                  85                  90                  95

 gct tgg cag ttc cct gtt aga ata cac ccc cca gat caa cag gga aat      336
 Ala Trp Gln Phe Pro Val Arg Ile His Pro Pro Asp Gln Gln Gly Asn
             100                 105                 110

 att ata gct aca ttt gag cct ttt cct ttt aaa ttc ggg aaa gca cat      384
 Ile Ile Ala Thr Phe Glu Pro Phe Pro Phe Lys Phe Gly Lys Ala His
         115                 120                 125

 tca gtt gat tat atc aag gcc tgt gat ggt atc gga ggt aat ctg cat      432
 Ser Val Asp Tyr Ile Lys Ala Cys Asp Gly Ile Gly Gly Asn Leu His
     130                 135                 140

 aaa gct act ttg ttg gca cag gca ctg gca gga ctg aga gtg gat aaa      480
 Lys Ala Thr Leu Leu Ala Gln Ala Leu Ala Gly Leu Arg Val Asp Lys
 145                 150                 155                 160

 gga aat act cca ttt cct gga gct tgt ttt aac tgt ggg aag cat ggt      528
 Gly Asn Thr Pro Phe Pro Gly Ala Cys Phe Asn Cys Gly Lys His Gly
                 165                 170                 175

 cat act aaa aaa gaa tgt aga aaa aat cag cga gtc agg ctg cca gat      576
 His Thr Lys Lys Glu Cys Arg Lys Asn Gln Arg Val Arg Leu Pro Asp
             180                 185                 190

 agg gga aaa aag aaa act gtt gag cct gaa ata tgt cca aaa tgt aaa      624
 Arg Gly Lys Lys Lys Thr Val Glu Pro Glu Ile Cys Pro Lys Cys Lys
         195                 200                 205

 aaa gga aaa cat tgg gct agt cag tgt cac tct aag ttt gat aaa gaa      672
 Lys Gly Lys His Trp Ala Ser Gln Cys His Ser Lys Phe Asp Lys Glu
     210                 215                 220

 aga aac cca att tca gga aat gcc atg agg ggc cca tcc cgg gcc ctg      720
 Arg Asn Pro Ile Ser Gly Asn Ala Met Arg Gly Pro Ser Arg Ala Leu
 225                 230                 235                 240

 ttc taa                                                              726
 Phe 






      <210> 572
      <211> 666
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(666)

      <400> 572
  atg atc acc ctg gct gca agg cac aga gcc acc cta ctt ctc ctg ctg      48
  Met Ile Thr Leu Ala Ala Arg His Arg Ala Thr Leu Leu Leu Leu Leu
    1               5                  10                  15

 gta aca cat aca cac atg cac atg cat gca tgc tgc atg cac aca cac       96
 Val Thr His Thr His Met His Met His Ala Cys Cys Met His Thr His
              20                  25                  30

 acc cct ggg aag tct cct gaa gtg gct ata cca gtt tac att cct gcc      144
 Thr Pro Gly Lys Ser Pro Glu Val Ala Ile Pro Val Tyr Ile Pro Ala
          35                  40                  45

 aac agt gca caa ggg ttt cat ttt ctc cac aga gga cag gcc ctc ctt      192
 Asn Ser Ala Gln Gly Phe His Phe Leu His Arg Gly Gln Ala Leu Leu
      50                  55                  60

 gat cag gct gcc tca tgg gat gat cag atc cga gcc tta ggg tgt gac      240
 Asp Gln Ala Ala Ser Trp Asp Asp Gln Ile Arg Ala Leu Gly Cys Asp
  65                  70                  75                  80

 gaa gga aat cct ttt gtc aaa cta aaa ggt gaa ctc agt gca gct gcc      288
 Glu Gly Asn Pro Phe Val Lys Leu Lys Gly Glu Leu Ser Ala Ala Ala
                  85                  90                  95

 ttc cta tca act ctg cgc att cct gaa ata ggg cag gca ttg ctg ctg      336
 Phe Leu Ser Thr Leu Arg Ile Pro Glu Ile Gly Gln Ala Leu Leu Leu
             100                 105                 110

 ggc tca agt gtc cca agg gat ttg acg ttc agc gga ggg gac cat gat      384
 Gly Ser Ser Val Pro Arg Asp Leu Thr Phe Ser Gly Gly Asp His Asp
         115                 120                 125

 tac ctg ttg gaa ggc agc aga ggc tct gct aga agg aca ggt gga ctg      432
 Tyr Leu Leu Glu Gly Ser Arg Gly Ser Ala Arg Arg Thr Gly Gly Leu
     130                 135                 140

 aag atg agc aga aag cca gag aac tcc ttg agg cat tgc cac agg ggg      480
 Lys Met Ser Arg Lys Pro Glu Asn Ser Leu Arg His Cys His Arg Gly
 145                 150                 155                 160

 gcg cta cag cat ttg aaa aga gac agt gga caa gca tct gca ggc agg      528
 Ala Leu Gln His Leu Lys Arg Asp Ser Gly Gln Ala Ser Ala Gly Arg
                 165                 170                 175

 cac ctg tct ttt ggg ttt gcc caa agc tcg gtg aga agt gaa cta tca      576
 His Leu Ser Phe Gly Phe Ala Gln Ser Ser Val Arg Ser Glu Leu Ser
             180                 185                 190

 ctg tgg cac tct ctt cat ttc ccc ctg aat ggg caa aac aac cca gtg      624
 Leu Trp His Ser Leu His Phe Pro Leu Asn Gly Gln Asn Asn Pro Val
         195                 200                 205

 aac gcg ccg cct gag aga gct gac tgg att tta gca atg tga              666
 Asn Ala Pro Pro Glu Arg Ala Asp Trp Ile Leu Ala Met 
     210                 215                 220





      <210> 573
      <211> 918
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(918)

      <400> 573
  atg agt aca gct gtg gtc gtg aag gtt gtg ctt tgt aca gta gca cct      48
  Met Ser Thr Ala Val Val Val Lys Val Val Leu Cys Thr Val Ala Pro
    1               5                  10                  15

 ggc agg ggc tct gct cct tcc tta agc tcg tgt ctt gac tgg aag gtc       96
 Gly Arg Gly Ser Ala Pro Ser Leu Ser Ser Cys Leu Asp Trp Lys Val
              20                  25                  30

 aat gga gca gag ggg agc cat aat aaa gat ctc ttt gtc ctt acc tat      144
 Asn Gly Ala Glu Gly Ser His Asn Lys Asp Leu Phe Val Leu Thr Tyr
          35                  40                  45

 gga gct ctg gtt gcc cag ctg tgt aag gat tat gag aag gat gaa gat      192
 Gly Ala Leu Val Ala Gln Leu Cys Lys Asp Tyr Glu Lys Asp Glu Asp
      50                  55                  60

 gtg aac caa tat tta gat aaa atg ggt tac ggc att gga acg cgg ctt      240
 Val Asn Gln Tyr Leu Asp Lys Met Gly Tyr Gly Ile Gly Thr Arg Leu
  65                  70                  75                  80

 gtg gaa gac ttt ttg gct cga tcc tgc gtg gga aga tgc cat agt tat      288
 Val Glu Asp Phe Leu Ala Arg Ser Cys Val Gly Arg Cys His Ser Tyr
                  85                  90                  95

 tca gaa att ata gac ata att gcc cag gac atg gag agg ggg ttc tgt      336
 Ser Glu Ile Ile Asp Ile Ile Ala Gln Asp Met Glu Arg Gly Phe Cys
             100                 105                 110

 gct ctc cac ata gac act gaa ggc aga tac gaa tgg tgg aca act tcc      384
 Ala Leu His Ile Asp Thr Glu Gly Arg Tyr Glu Trp Trp Thr Thr Ser
         115                 120                 125

 act cag ctc caa tct act tta cct cga gca gca cag tgc tct gtc tac      432
 Thr Gln Leu Gln Ser Thr Leu Pro Arg Ala Ala Gln Cys Ser Val Tyr
     130                 135                 140

 caa aag cag cct gac agg aaa tcc cta act gta ggc caa aag att gaa      480
 Gln Lys Gln Pro Asp Arg Lys Ser Leu Thr Val Gly Gln Lys Ile Glu
 145                 150                 155                 160

 gta gga aac cca ggt att gga acg gaa cag agt ccc cag ggt cta gtg      528
 Val Gly Asn Pro Gly Ile Gly Thr Glu Gln Ser Pro Gln Gly Leu Val
                 165                 170                 175

 aga ttt gca acc cag gca ttc ctt acc acg cac aga gct gaa ggg ttg      576
 Arg Phe Ala Thr Gln Ala Phe Leu Thr Thr His Arg Ala Glu Gly Leu
             180                 185                 190

 cag caa agc caa gtg aaa ggc tca gtt att cac ctg aag agt cag gac      624
 Gln Gln Ser Gln Val Lys Gly Ser Val Ile His Leu Lys Ser Gln Asp
         195                 200                 205

 aaa tgt gga gaa cac agg ttc aca aca aac cag gta gaa aca gga gac      672
 Lys Cys Gly Glu His Arg Phe Thr Thr Asn Gln Val Glu Thr Gly Asp
     210                 215                 220

 ccg gtc aga gag agc agt tct cag cac agt gta ggc agg gga gga ccc      720
 Pro Val Arg Glu Ser Ser Ser Gln His Ser Val Gly Arg Gly Gly Pro
 225                 230                 235                 240

 aag gat att caa atc cag ggt gcc aat gtc cca gtt cgg cag tgt aac      768
 Lys Asp Ile Gln Ile Gln Gly Ala Asn Val Pro Val Arg Gln Cys Asn
                 245                 250                 255

 ctc ctc tgg agg atc acc ctt ggg cca ctg gag act cct cac ctg gag      816
 Leu Leu Trp Arg Ile Thr Leu Gly Pro Leu Glu Thr Pro His Leu Glu
             260                 265                 270

 ttt tct ggg gaa tgc tct ctc ttg gct gca atg gaa gcc cca gag cac      864
 Phe Ser Gly Glu Cys Ser Leu Leu Ala Ala Met Glu Ala Pro Glu His
         275                 280                 285

 act tgg gat cag gag aaa tct gac att cca gag ccc ccc cat agg tca      912
 Thr Trp Asp Gln Glu Lys Ser Asp Ile Pro Glu Pro Pro His Arg Ser
     290                 295                 300

 agc tga                                                              918
 Ser 
 305





      <210> 574
      <211> 693
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(693)

      <400> 574
  atg gaa gca gtg ctg ttt cca gct tgt ctc tgc cac agg gtc ctt ctc      48
  Met Glu Ala Val Leu Phe Pro Ala Cys Leu Cys His Arg Val Leu Leu
    1               5                  10                  15

 tgc tct ctc agc ctg aag gcc tcc tct gtg tct gga ccc ctg aga aga       96
 Cys Ser Leu Ser Leu Lys Ala Ser Ser Val Ser Gly Pro Leu Arg Arg
              20                  25                  30

 cca gtg tgc atg aac cag aga ctg gac agt gcc tct gtt acc atc acc      144
 Pro Val Cys Met Asn Gln Arg Leu Asp Ser Ala Ser Val Thr Ile Thr
          35                  40                  45

 gtg tgg tat cat gaa gag ggt tgc ttt ctc tat gga tca agg caa aat      192
 Val Trp Tyr His Glu Glu Gly Cys Phe Leu Tyr Gly Ser Arg Gln Asn
      50                  55                  60

 gag tac ctt aag tct aga gcc cca ggt gaa atg aag aac caa gga tca      240
 Glu Tyr Leu Lys Ser Arg Ala Pro Gly Glu Met Lys Asn Gln Gly Ser
  65                  70                  75                  80

 tct gag caa aga ctc aag gac cat ttg aac aaa gac atc cac atc tat      288
 Ser Glu Gln Arg Leu Lys Asp His Leu Asn Lys Asp Ile His Ile Tyr
                  85                  90                  95

 acc aca gat gac ttg gca tct atg gag gag tgg aga aac cag atc ccc      336
 Thr Thr Asp Asp Leu Ala Ser Met Glu Glu Trp Arg Asn Gln Ile Pro
             100                 105                 110

 aaa gag gaa cac tac ggc ctg caa ttg cac cct gcc atc cac cag ctc      384
 Lys Glu Glu His Tyr Gly Leu Gln Leu His Pro Ala Ile His Gln Leu
         115                 120                 125

 aag act gag gaa tgc aac cat acc cag aca gac ttt ttc aca aga caa      432
 Lys Thr Glu Glu Cys Asn His Thr Gln Thr Asp Phe Phe Thr Arg Gln
     130                 135                 140

 ttt ctg cct ctg gag cgt gtt caa att cta aag agc atc att tac aag      480
 Phe Leu Pro Leu Glu Arg Val Gln Ile Leu Lys Ser Ile Ile Tyr Lys
 145                 150                 155                 160

 cca cta ctc tat ctt cct ctg ttt gaa tcc aaa cag aag tac aag gag      528
 Pro Leu Leu Tyr Leu Pro Leu Phe Glu Ser Lys Gln Lys Tyr Lys Glu
                 165                 170                 175

 tca gat cca caa atg agt cgt ttt atc ttg ccc tac ctc tct gtg cag      576
 Ser Asp Pro Gln Met Ser Arg Phe Ile Leu Pro Tyr Leu Ser Val Gln
             180                 185                 190

 tca atg gcc aac cat cct atg gat gga cag tca cag ggg ccc aac caa      624
 Ser Met Ala Asn His Pro Met Asp Gly Gln Ser Gln Gly Pro Asn Gln
         195                 200                 205

 ggt gtc tta tac gag cag gca gag ggc ttg cag tgg ctt ttt gta ggt      672
 Gly Val Leu Tyr Glu Gln Ala Glu Gly Leu Gln Trp Leu Phe Val Gly
     210                 215                 220

 ttt tgg ctg gag ctg aac taa                                          693
 Phe Trp Leu Glu Leu Asn 
 225                 230





      <210> 575
      <211> 564
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(564)

      <400> 575
  atg aaa gat tgg agc tat ggg gat agt ggg cct ttg gcc ctt ctt atc      48
  Met Lys Asp Trp Ser Tyr Gly Asp Ser Gly Pro Leu Ala Leu Leu Ile
    1               5                  10                  15

 agg atg aaa acg ctt ctg ttt ggt gtc tgg acc ctg ctg gcc ttg atc       96
 Arg Met Lys Thr Leu Leu Phe Gly Val Trp Thr Leu Leu Ala Leu Ile
              20                  25                  30

 ctt tgc cca gag cca cca gag caa gtg atc ctg gag ctg cag cct gcc      144
 Leu Cys Pro Glu Pro Pro Glu Gln Val Ile Leu Glu Leu Gln Pro Ala
          35                  40                  45

 tgg gtg gct gtg gac gaa gcc ttc aca gtg aag tgt cat gta ccc agt      192
 Trp Val Ala Val Asp Glu Ala Phe Thr Val Lys Cys His Val Pro Ser
      50                  55                  60

 gta gca ccc ttg gag agt ctc acc ctt gcc ctt ctc cag ggt aac caa      240
 Val Ala Pro Leu Glu Ser Leu Thr Leu Ala Leu Leu Gln Gly Asn Gln
  65                  70                  75                  80

 gaa ctg cat aga aag aac ttt acg agc ttg gct gtg gcc tcc caa aga      288
 Glu Leu His Arg Lys Asn Phe Thr Ser Leu Ala Val Ala Ser Gln Arg
                  85                  90                  95

 gct gaa gtc atc atc agt gtc aga gcc caa aag gag aat gac aga tgc      336
 Ala Glu Val Ile Ile Ser Val Arg Ala Gln Lys Glu Asn Asp Arg Cys
             100                 105                 110

 aat tct tcc tgc cat gca gaa ctg gac ttg agt ttg caa ggc ttc cct      384
 Asn Ser Ser Cys His Ala Glu Leu Asp Leu Ser Leu Gln Gly Phe Pro
         115                 120                 125

 cca cca atc ctg gag cta aaa gaa tca tac cca ttg gca ggg acc gac      432
 Pro Pro Ile Leu Glu Leu Lys Glu Ser Tyr Pro Leu Ala Gly Thr Asp
     130                 135                 140

 att aat gtg acc tgc tca ggg cat gta tta aca tca ccc agc cct act      480
 Ile Asn Val Thr Cys Ser Gly His Val Leu Thr Ser Pro Ser Pro Thr
 145                 150                 155                 160

 ctt cgg ctt cag gga gcc cca gac ctc cct gct ggg gag cct gcc tgg      528
 Leu Arg Leu Gln Gly Ala Pro Asp Leu Pro Ala Gly Glu Pro Ala Trp
                 165                 170                 175

 ctt cta ctt act gcc agg gag gaa gat gat ggc tga                      564
 Leu Leu Leu Thr Ala Arg Glu Glu Asp Asp Gly 
             180                 185





      <210> 576
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 576
  atg atg ggg aac ata gta aga cca gtg aat tcc atg agc ctg agc cca      48
  Met Met Gly Asn Ile Val Arg Pro Val Asn Ser Met Ser Leu Ser Pro
    1               5                  10                  15

 ctg ctg ccc tta ttt agc tgt aaa gtg agt gtc ttg gtc aga ggc aat       96
 Leu Leu Pro Leu Phe Ser Cys Lys Val Ser Val Leu Val Arg Gly Asn
              20                  25                  30

 gct gtg tgg aat acc atg atg gtg gat aag gca ttc cat gac tcc aca      144
 Ala Val Trp Asn Thr Met Met Val Asp Lys Ala Phe His Asp Ser Thr
          35                  40                  45

 gat ggt agt ctt ggc aga agc att gtg tgc agg ata ggc aaa ccc tta      192
 Asp Gly Ser Leu Gly Arg Ser Ile Val Cys Arg Ile Gly Lys Pro Leu
      50                  55                  60

 tcc aga gga agt gtc tat tcc act gaa ggc aaa ttg ctc ctg gtg ggc      240
 Ser Arg Gly Ser Val Tyr Ser Thr Glu Gly Lys Leu Leu Leu Val Gly
  65                  70                  75                  80

 ctt atg gac agg aat gaa gaa aag gca ttt gtc aaa tcg atg gct gca      288
 Leu Met Asp Arg Asn Glu Glu Lys Ala Phe Val Lys Ser Met Ala Ala
                  85                  90                  95

 tac cgg gta cca gga gat gtg tta att tgc cca agc aat gaa acc aca      336
 Tyr Arg Val Pro Gly Asp Val Leu Ile Cys Pro Ser Asn Glu Thr Thr
             100                 105                 110

 tct ggt ata gca gct gca att gga atc acc act tgg tta acc tta tga      384
 Ser Gly Ile Ala Ala Ala Ile Gly Ile Thr Thr Trp Leu Thr Leu 
         115                 120                 125





      <210> 577
      <211> 588
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(588)

      <400> 577
  atg aaa ctg ttt caa ttt ttg aaa tta act aat tgg gtt ctc cct aaa      48
  Met Lys Leu Phe Gln Phe Leu Lys Leu Thr Asn Trp Val Leu Pro Lys
    1               5                  10                  15

 ata act aaa ttt ata cca att gaa ggt gct gaa aat gtc ttc aca gat       96
 Ile Thr Lys Phe Ile Pro Ile Glu Gly Ala Glu Asn Val Phe Thr Asp
              20                  25                  30

 ggg tct agt aat ggt aaa gct tct tat tct ggc tca aaa tgt aaa gtt      144
 Gly Ser Ser Asn Gly Lys Ala Ser Tyr Ser Gly Ser Lys Cys Lys Val
          35                  40                  45

 ttc cag acg ccc tat act tta gct cca aaa gtg gag ctc gta gct gta      192
 Phe Gln Thr Pro Tyr Thr Leu Ala Pro Lys Val Glu Leu Val Ala Val
      50                  55                  60

 att gag gta ttg act gct ttt gat atg cat att aat gtg att tct gat      240
 Ile Glu Val Leu Thr Ala Phe Asp Met His Ile Asn Val Ile Ser Asp
  65                  70                  75                  80

 tct tca tat gtg gtt cat tcc aca caa tta act gaa aat gct cag tta      288
 Ser Ser Tyr Val Val His Ser Thr Gln Leu Thr Glu Asn Ala Gln Leu
                  85                  90                  95

 cga ttt cat aca gat gag caa ctg ata act ttg ttt acc caa ttg caa      336
 Arg Phe His Thr Asp Glu Gln Leu Ile Thr Leu Phe Thr Gln Leu Gln
             100                 105                 110

 aca gca gtt agg agt aga atg gct cat aca cct ctt cca gga ctt ttg      384
 Thr Ala Val Arg Ser Arg Met Ala His Thr Pro Leu Pro Gly Leu Leu
         115                 120                 125

 act gca ggg aat caa atg gct gat cgc cta gtt gct act gca ata tct      432
 Thr Ala Gly Asn Gln Met Ala Asp Arg Leu Val Ala Thr Ala Ile Ser
     130                 135                 140

 aat gcc aga cac ttt cgc aat tta acc cat gtt aat gcc tct ggt ctc      480
 Asn Ala Arg His Phe Arg Asn Leu Thr His Val Asn Ala Ser Gly Leu
 145                 150                 155                 160

 aaa cgc aga tac agc att acc tgg aaa aaa gct aaa gct att atc cag      528
 Lys Arg Arg Tyr Ser Ile Thr Trp Lys Lys Ala Lys Ala Ile Ile Gln
                 165                 170                 175

 cat tgc cca act tgc cac atg gtg cat tcc tca tct ttt aca gga gga      576
 His Cys Pro Thr Cys His Met Val His Ser Ser Ser Phe Thr Gly Gly
             180                 185                 190

 gtt aat cct tga                                                      588
 Val Asn Pro 
         195





      <210> 578
      <211> 486
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(486)

      <400> 578
  atg gcc aca cgg gtc caa gcg aga gct tgc ctc ctc ccc gcc ctt gct      48
  Met Ala Thr Arg Val Gln Ala Arg Ala Cys Leu Leu Pro Ala Leu Ala
    1               5                  10                  15

 ccc cga ata cca acc ctg gaa agg aat gaa ttc agg gca tgg acg gac       96
 Pro Arg Ile Pro Thr Leu Glu Arg Asn Glu Phe Arg Ala Trp Thr Asp
              20                  25                  30

 atc aag cct gtg aaa cca ata aag gcc aag ccc cag tac aag ccc cca      144
 Ile Lys Pro Val Lys Pro Ile Lys Ala Lys Pro Gln Tyr Lys Pro Pro
          35                  40                  45

 gat gat aag atg gtt cat gag acc agc tac agt gct cag ttc aaa gga      192
 Asp Asp Lys Met Val His Glu Thr Ser Tyr Ser Ala Gln Phe Lys Gly
      50                  55                  60

 gag gcc agc aag cca aca aca gct gac aat aag gtc att gat cgc aga      240
 Glu Ala Ser Lys Pro Thr Thr Ala Asp Asn Lys Val Ile Asp Arg Arg
  65                  70                  75                  80

 aga ata cgc agc ctc tac agc gaa ccc ttc aag gaa ccc cca aag gtg      288
 Arg Ile Arg Ser Leu Tyr Ser Glu Pro Phe Lys Glu Pro Pro Lys Val
                  85                  90                  95

 gaa aaa cct agt gtt cag agt tcc aaa cca aaa aag acc tca gcg agc      336
 Glu Lys Pro Ser Val Gln Ser Ser Lys Pro Lys Lys Thr Ser Ala Ser
             100                 105                 110

 cat aag ccc acg agg aag gcc aaa gac aag cag gcg gtg tca ggc cag      384
 His Lys Pro Thr Arg Lys Ala Lys Asp Lys Gln Ala Val Ser Gly Gln
         115                 120                 125

 gct gcc aag aaa aag agc gcg gag ggc ccg agt acc acc aag cca gac      432
 Ala Ala Lys Lys Lys Ser Ala Glu Gly Pro Ser Thr Thr Lys Pro Asp
     130                 135                 140

 gac aag gag caa agc aaa gag atg aac aat aaa ctg gct gag gcg aaa      480
 Asp Lys Glu Gln Ser Lys Glu Met Asn Asn Lys Leu Ala Glu Ala Lys
 145                 150                 155                 160

 gag taa                                                              486
 Glu 






      <210> 579
      <211> 546
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(546)

      <400> 579
  atg gcg cta gca ctg agt ggg ctc aaa ctc tgt acg cgt tta cta agc      48
  Met Ala Leu Ala Leu Ser Gly Leu Lys Leu Cys Thr Arg Leu Leu Ser
    1               5                  10                  15

 ata ttg act gaa gaa atc tgg aaa cct agt acc gcg gca cca tat cgt       96
 Ile Leu Thr Glu Glu Ile Trp Lys Pro Ser Thr Ala Ala Pro Tyr Arg
              20                  25                  30

 tac ccc aaa gga aaa tgc atg cac gct gtc aga gat gac gaa cac tgc      144
 Tyr Pro Lys Gly Lys Cys Met His Ala Val Arg Asp Asp Glu His Cys
          35                  40                  45

 gtc tgg aaa ctt ctt aag ggc acc cac gtg tcc tca gct gca gac agc      192
 Val Trp Lys Leu Leu Lys Gly Thr His Val Ser Ser Ala Ala Asp Ser
      50                  55                  60

 agc gag gag aca ccc agg gaa ttc gag aca gcg gaa ggc gga agg gtc      240
 Ser Glu Glu Thr Pro Arg Glu Phe Glu Thr Ala Glu Gly Gly Arg Val
  65                  70                  75                  80

 ccg caa caa ccc acc ctc cag ctc agg cct ttg aaa ttt tca gcc act      288
 Pro Gln Gln Pro Thr Leu Gln Leu Arg Pro Leu Lys Phe Ser Ala Thr
                  85                  90                  95

 ttt ctt aat tat gac gat ggg act gaa gct cta gag gga agt cac tta      336
 Phe Leu Asn Tyr Asp Asp Gly Thr Glu Ala Leu Glu Gly Ser His Leu
             100                 105                 110

 cca gag ggt gta ggt tct tca tcc aga gct gaa gtc ttc ttg ggg gtt      384
 Pro Glu Gly Val Gly Ser Ser Ser Arg Ala Glu Val Phe Leu Gly Val
         115                 120                 125

 ctt gag cac gtg ccc ctg ctg ctg tat atc ttg gca gca aaa aca tta      432
 Leu Glu His Val Pro Leu Leu Leu Tyr Ile Leu Ala Ala Lys Thr Leu
     130                 135                 140

 att ctc tgc ctg aca ttt gct ggg gtg aaa atg tat caa aga aaa agg      480
 Ile Leu Cys Leu Thr Phe Ala Gly Val Lys Met Tyr Gln Arg Lys Arg
 145                 150                 155                 160

 ttg gag gca aaa caa caa aaa ctg gag gct gaa agg aag aag caa tca      528
 Leu Glu Ala Lys Gln Gln Lys Leu Glu Ala Glu Arg Lys Lys Gln Ser
                 165                 170                 175

 gag aaa aaa gat aac tga                                              546
 Glu Lys Lys Asp Asn 
             180





      <210> 580
      <211> 495
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(495)

      <400> 580
  atg ctg tcc aag agc caa tgc ctg aaa ttg gtg acc cta aaa gcc cac      48
  Met Leu Ser Lys Ser Gln Cys Leu Lys Leu Val Thr Leu Lys Ala His
    1               5                  10                  15

 ttg gtg ctc tac tcc act gtt acc aag gta gtg ctt aaa ggt aat tat       96
 Leu Val Leu Tyr Ser Thr Val Thr Lys Val Val Leu Lys Gly Asn Tyr
              20                  25                  30

 cca gtt gat att tat ctt gtt cca gtc acc ttt aga aag ctg ttt gga      144
 Pro Val Asp Ile Tyr Leu Val Pro Val Thr Phe Arg Lys Leu Phe Gly
          35                  40                  45

 tct tgg agg gaa aat gct agg gac aag atg atc agt gta tat gaa aat      192
 Ser Trp Arg Glu Asn Ala Arg Asp Lys Met Ile Ser Val Tyr Glu Asn
      50                  55                  60

 tgg aag tta gtt cag tta aga aca tct aag cta aaa tac gaa cgg cag      240
 Trp Lys Leu Val Gln Leu Arg Thr Ser Lys Leu Lys Tyr Glu Arg Gln
  65                  70                  75                  80

 agg acc cat gtg gtc aaa gat gtc ccg gtg gcc ctg ttc ctt tca ctc      288
 Arg Thr His Val Val Lys Asp Val Pro Val Ala Leu Phe Leu Ser Leu
                  85                  90                  95

 aga aac ttt gaa gca ggt tct tac caa atg ctc ttt act gta tca gga      336
 Arg Asn Phe Glu Ala Gly Ser Tyr Gln Met Leu Phe Thr Val Ser Gly
             100                 105                 110

 gaa caa aga ttg aag aag gaa ctg aca ctg gca gtg gtt tta att gga      384
 Glu Gln Arg Leu Lys Lys Glu Leu Thr Leu Ala Val Val Leu Ile Gly
         115                 120                 125

 gtc cat cct ggc tat gaa ggt ctg ctt gct tct ccc agc aac cag acc      432
 Val His Pro Gly Tyr Glu Gly Leu Leu Ala Ser Pro Ser Asn Gln Thr
     130                 135                 140

 ttg acg tat tcg ttc act gac aat gaa aga ggc agc caa ggt gta cag      480
 Leu Thr Tyr Ser Phe Thr Asp Asn Glu Arg Gly Ser Gln Gly Val Gln
 145                 150                 155                 160

 atc ttc atg gtg tag                                                  495
 Ile Phe Met Val 






      <210> 581
      <211> 477
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(477)

      <400> 581
  atg gct aga ctg gaa gca ctt ggc cct ctt ggg ctc tgc acc ccc acc      48
  Met Ala Arg Leu Glu Ala Leu Gly Pro Leu Gly Leu Cys Thr Pro Thr
    1               5                  10                  15

 ccc tcc cac ctg gcc tgc ctg ctc atc ttc atg ggc gcc tgg gga gac       96
 Pro Ser His Leu Ala Cys Leu Leu Ile Phe Met Gly Ala Trp Gly Asp
              20                  25                  30

 caa tta tgg ctg ctt gtc ata gtg gct cag gtc acc gtt cac act tcc      144
 Gln Leu Trp Leu Leu Val Ile Val Ala Gln Val Thr Val His Thr Ser
          35                  40                  45

 tgg gac cag gac atc aga gcc ctg aga agg gtc aag ggg cca agt ggg      192
 Trp Asp Gln Asp Ile Arg Ala Leu Arg Arg Val Lys Gly Pro Ser Gly
      50                  55                  60

 cct agc ctt tta ctg aca gct ggg aaa tgc aag cgt gtg gac cag agc      240
 Pro Ser Leu Leu Leu Thr Ala Gly Lys Cys Lys Arg Val Asp Gln Ser
  65                  70                  75                  80

 acc aag ggg tct ctg ggc aga cac cgc aag tcg gtg att gtg atg cct      288
 Thr Lys Gly Ser Leu Gly Arg His Arg Lys Ser Val Ile Val Met Pro
                  85                  90                  95

 ctg gag ggg gtg ctg gtc atg gga gat tgc ttg ttt gct gga gat ccc      336
 Leu Glu Gly Val Leu Val Met Gly Asp Cys Leu Phe Ala Gly Asp Pro
             100                 105                 110

 atg tac ctt ttg att gct gaa gca ggt gaa tgt acg cct ttc caa gaa      384
 Met Tyr Leu Leu Ile Ala Glu Ala Gly Glu Cys Thr Pro Phe Gln Glu
         115                 120                 125

 att aaa atg ggc cag aat tca gaa cgc tca gaa atc cca aag gtt ctt      432
 Ile Lys Met Gly Gln Asn Ser Glu Arg Ser Glu Ile Pro Lys Val Leu
     130                 135                 140

 cta agt ctg cag cag act aat ttc tgc tgc aaa aat ctg acc tga          477
 Leu Ser Leu Gln Gln Thr Asn Phe Cys Cys Lys Asn Leu Thr 
 145                 150                 155





      <210> 582
      <211> 756
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(756)

      <400> 582
  atg ggt tca tgg cta caa gga cta agg gct atg gtt ttt gca ctg aac      48
  Met Gly Ser Trp Leu Gln Gly Leu Arg Ala Met Val Phe Ala Leu Asn
    1               5                  10                  15

 tac atg gtt acc aga gtt aga aac aaa aaa gat cca cct aca acc tca       96
 Tyr Met Val Thr Arg Val Arg Asn Lys Lys Asp Pro Pro Thr Thr Ser
              20                  25                  30

 ggt cct cag acc cac cag ccc aag aaa cat ctc acc aat ttc aaa tcc      144
 Gly Pro Gln Thr His Gln Pro Lys Lys His Leu Thr Asn Phe Lys Ser
          35                  40                  45

 gag aca aag gag aca cgt ttt atc tgt gga ccc aaa act ccg gcg ccg      192
 Glu Thr Lys Glu Thr Arg Phe Ile Cys Gly Pro Lys Thr Pro Ala Pro
      50                  55                  60

 ctc atg gac tgg gaa ggc agc ctt ccc ttg atg ttt aat cat tgc agg      240
 Leu Met Asp Trp Glu Gly Ser Leu Pro Leu Met Phe Asn His Cys Arg
  65                  70                  75                  80

 gac acc tct ctg att att cac cca tgt ttc caa ggt gtc aga cca tgc      288
 Asp Thr Ser Leu Ile Ile His Pro Cys Phe Gln Gly Val Arg Pro Cys
                  85                  90                  95

 agg gac gcc tgc ctt agt cct tca ccc tta gcg gca agt ccc gct ttt      336
 Arg Asp Ala Cys Leu Ser Pro Ser Pro Leu Ala Ala Ser Pro Ala Phe
             100                 105                 110

 ctg ggg aag ggg caa gta ccc ctc aac ccc ttc ttc acc ctt agt ggc      384
 Leu Gly Lys Gly Gln Val Pro Leu Asn Pro Phe Phe Thr Leu Ser Gly
         115                 120                 125

 aag tcc cgc ttt tct ggg gga gga gca agt acc cca acc cct tct ttc      432
 Lys Ser Arg Phe Ser Gly Gly Gly Ala Ser Thr Pro Thr Pro Ser Phe
     130                 135                 140

 cat gtc tct acg cct tct ctg ctt ttc tgg gga agg ggc aag tac ccc      480
 His Val Ser Thr Pro Ser Leu Leu Phe Trp Gly Arg Gly Lys Tyr Pro
 145                 150                 155                 160

 tca acc cct tct tca ccc tta gtg gca agt ccc gct ttt ctg ggg aag      528
 Ser Thr Pro Ser Ser Pro Leu Val Ala Ser Pro Ala Phe Leu Gly Lys
                 165                 170                 175

 ggg caa gta ccc ctc aac ccc ttc ttc acc ctt agt ggc aag tcc cgc      576
 Gly Gln Val Pro Leu Asn Pro Phe Phe Thr Leu Ser Gly Lys Ser Arg
             180                 185                 190

 ttt tct ggg gaa ggg gca aaa gcc ccc gag acc atc acg gat gcc gag      624
 Phe Ser Gly Glu Gly Ala Lys Ala Pro Glu Thr Ile Thr Asp Ala Glu
         195                 200                 205

 ctt cgg gta act ctc aca gtg gag gct gct gta tgt tca acc atc gcc      672
 Leu Arg Val Thr Leu Thr Val Glu Ala Ala Val Cys Ser Thr Ile Ala
     210                 215                 220

 tta agc cta ggg tgg gaa att ctt cct cga cac tgg ggt aaa gag gag      720
 Leu Ser Leu Gly Trp Glu Ile Leu Pro Arg His Trp Gly Lys Glu Glu
 225                 230                 235                 240

 gta acc aaa aca att tat tat cct gtg att cca taa                      756
 Val Thr Lys Thr Ile Tyr Tyr Pro Val Ile Pro 
                 245                 250





      <210> 583
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 583
  atg ggt ttg att gtg gtc acc ctc ttt gtc tct tcc att acc cct ggt      48
  Met Gly Leu Ile Val Val Thr Leu Phe Val Ser Ser Ile Thr Pro Gly
    1               5                  10                  15

 act gag agg gtg caa gct ggc act gat ccc agt tta tcc ttt gag att       96
 Thr Glu Arg Val Gln Ala Gly Thr Asp Pro Ser Leu Ser Phe Glu Ile
              20                  25                  30

 cag cag aag atc ctg atg gag gag gag gat acc aag aga gag gtg ccc      144
 Gln Gln Lys Ile Leu Met Glu Glu Glu Asp Thr Lys Arg Glu Val Pro
          35                  40                  45

 aag gaa gat gga gtt ggt gat gtg caa cat ttc gga aga gga gga agg      192
 Lys Glu Asp Gly Val Gly Asp Val Gln His Phe Gly Arg Gly Gly Arg
      50                  55                  60

 aaa tga                                                              198
 Lys 
  65





      <210> 584
      <211> 303
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(303)

      <400> 584
  atg gac cgc tgc ccc tcc atc ctg ccc ttg ccc gtg cgt ttg gtg ttt      48
  Met Asp Arg Cys Pro Ser Ile Leu Pro Leu Pro Val Arg Leu Val Phe
    1               5                  10                  15

 cag atc cta ctc acg gga ggc agc tgc gcg gag ggc atg aag cac cgt       96
 Gln Ile Leu Leu Thr Gly Gly Ser Cys Ala Glu Gly Met Lys His Arg
              20                  25                  30

 gtg cag aga tct gtg ggc aaa agc cca gga cgt gac ctt agg caa gag      144
 Val Gln Arg Ser Val Gly Lys Ser Pro Gly Arg Asp Leu Arg Gln Glu
          35                  40                  45

 ggg tcc ttg gag aag tgg agg tgt gca tgg tgt gta gcc ttg cgt gtc      192
 Gly Ser Leu Glu Lys Trp Arg Cys Ala Trp Cys Val Ala Leu Arg Val
      50                  55                  60

 tgt gag cac gcc cta gtg gac ctg cgc ctg gat tat cgg gcc agt ctc      240
 Cys Glu His Ala Leu Val Asp Leu Arg Leu Asp Tyr Arg Ala Ser Leu
  65                  70                  75                  80

 tcg gag ggg tcc gtg atg ctg agt tac gcc att cac ctg aac tct gca      288
 Ser Glu Gly Ser Val Met Leu Ser Tyr Ala Ile His Leu Asn Ser Ala
                  85                  90                  95

 gct cat cgg ctg tag                                                  303
 Ala His Arg Leu 
             100





      <210> 585
      <211> 633
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(633)

      <400> 585
  atg tgg ctg cct gct gtg gcc ctg ctg gct ggc tca ggc tgg tgt ccc      48
  Met Trp Leu Pro Ala Val Ala Leu Leu Ala Gly Ser Gly Trp Cys Pro
    1               5                  10                  15

 ggg ccc aga ccc cct gtg ccc agc agc cag agg agt ctg gtc cag cgg       96
 Gly Pro Arg Pro Pro Val Pro Ser Ser Gln Arg Ser Leu Val Gln Arg
              20                  25                  30

 aag ttg aag cag gca ccc cct gca gga ctg ctc cag caa atc ccc tac      144
 Lys Leu Lys Gln Ala Pro Pro Ala Gly Leu Leu Gln Gln Ile Pro Tyr
          35                  40                  45

 cct tta gaa caa aac tcc aag ccc gtc ctg tgg aag tgg act tgg act      192
 Pro Leu Glu Gln Asn Ser Lys Pro Val Leu Trp Lys Trp Thr Trp Thr
      50                  55                  60

 gca cag acc gaa ctt ggt caa agc cag gag gca gga cac agg ctc ctg      240
 Ala Gln Thr Glu Leu Gly Gln Ser Gln Glu Ala Gly His Arg Leu Leu
  65                  70                  75                  80

 ggc cca gat cca gag ctg gac gcc gag tct ctg ggc agg aaa tca ggg      288
 Gly Pro Asp Pro Glu Leu Asp Ala Glu Ser Leu Gly Arg Lys Ser Gly
                  85                  90                  95

 ctc cag ggc ccc tgg gct gcc ggc atg gag gct ggg agc tcc ctg gac      336
 Leu Gln Gly Pro Trp Ala Ala Gly Met Glu Ala Gly Ser Ser Leu Asp
             100                 105                 110

 acc gga agc agc ctc tcc act gac cgc tac agg acg aag aaa aat atc      384
 Thr Gly Ser Ser Leu Ser Thr Asp Arg Tyr Arg Thr Lys Lys Asn Ile
         115                 120                 125

 agt gtg gaa att aat gaa atg aaa aac aga aaa acc ata ccg acg atc      432
 Ser Val Glu Ile Asn Glu Met Lys Asn Arg Lys Thr Ile Pro Thr Ile
     130                 135                 140

 aat gaa acc aaa cct gat tct ttg aga aga cca gtg aaa gta ata act      480
 Asn Glu Thr Lys Pro Asp Ser Leu Arg Arg Pro Val Lys Val Ile Thr
 145                 150                 155                 160

 ctg tgg tca gac cga tcc aga aga aaa cga gaa aag aca caa att acc      528
 Leu Trp Ser Asp Arg Ser Arg Arg Lys Arg Glu Lys Thr Gln Ile Thr
                 165                 170                 175

 aat acc agg aat gag aac agt gac act gct aca gat tct gca gcc ttg      576
 Asn Thr Arg Asn Glu Asn Ser Asp Thr Ala Thr Asp Ser Ala Ala Leu
             180                 185                 190

 ctg ctg ggg cta cct ttc acc cac atg cag gct tac ttg cct gca ccc      624
 Leu Leu Gly Leu Pro Phe Thr His Met Gln Ala Tyr Leu Pro Ala Pro
         195                 200                 205

 ccg gca tga                                                          633
 Pro Ala 
     210





      <210> 586
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 586
  atg gcc gct tcc tgg aac tgc cta aga tgg cgg tcg cgg gct ctg ctg      48
  Met Ala Ala Ser Trp Asn Cys Leu Arg Trp Arg Ser Arg Ala Leu Leu
    1               5                  10                  15

 tgg acc gcg gcg ctg ctg tgc agc cca gcc gcg gca aaa tcc gtt ctc       96
 Trp Thr Ala Ala Leu Leu Cys Ser Pro Ala Ala Ala Lys Ser Val Leu
              20                  25                  30

 tcc atc gct gat gga gat gaa ata gag aga tgg gag tgg aaa gga aac      144
 Ser Ile Ala Asp Gly Asp Glu Ile Glu Arg Trp Glu Trp Lys Gly Asn
          35                  40                  45

 ttt act ctc aaa gga gtc cag att ctt tgt cct cga gaa att cgg gga      192
 Phe Thr Leu Lys Gly Val Gln Ile Leu Cys Pro Arg Glu Ile Arg Gly
      50                  55                  60

 aac acc ttc gaa gag gtg ggg ttg agg acc ttc ttt ctg aaa aca aaa      240
 Asn Thr Phe Glu Glu Val Gly Leu Arg Thr Phe Phe Leu Lys Thr Lys
  65                  70                  75                  80

 gct tcc tac tct tct gtg tcc tct ggc aac gag agg gat cct gat ctt      288
 Ala Ser Tyr Ser Ser Val Ser Ser Gly Asn Glu Arg Asp Pro Asp Leu
                  85                  90                  95

 tta cgt gaa cca gca gct cca cag agt tct ccg ttg caa aat cca aaa      336
 Leu Arg Glu Pro Ala Ala Pro Gln Ser Ser Pro Leu Gln Asn Pro Lys
             100                 105                 110

 gga gac tgt gga agg aga atc tgc ttt ttt gct ccc aat aag aag cag      384
 Gly Asp Cys Gly Arg Arg Ile Cys Phe Phe Ala Pro Asn Lys Lys Gln
         115                 120                 125

 ggc ttt atg ctg ttg cta gta tga                                      408
 Gly Phe Met Leu Leu Leu Val 
     130                 135





      <210> 587
      <211> 1029
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1029)

      <400> 587
  atg gcc cga agt gag gga gct tgg gtt ggc tgc aaa cta gcc gtg caa      48
  Met Ala Arg Ser Glu Gly Ala Trp Val Gly Cys Lys Leu Ala Val Gln
    1               5                  10                  15

 ctc agt cac cac atg agc ctg gca tgg ctg aaa gtc acc aca acg gtc       96
 Leu Ser His His Met Ser Leu Ala Trp Leu Lys Val Thr Thr Thr Val
              20                  25                  30

 aaa atg ctg ctg tgt gag gct ctc ttt caa ggc acc tat cca cag aag      144
 Lys Met Leu Leu Cys Glu Ala Leu Phe Gln Gly Thr Tyr Pro Gln Lys
          35                  40                  45

 gtg tac tgt ctc cca ggg gtg gtt ccc ctc aca cac gac att caa atc      192
 Val Tyr Cys Leu Pro Gly Val Val Pro Leu Thr His Asp Ile Gln Ile
      50                  55                  60

 agc att gtc att tta cgt att ttt aaa tgc ctt cga att gtg aag ctc      240
 Ser Ile Val Ile Leu Arg Ile Phe Lys Cys Leu Arg Ile Val Lys Leu
  65                  70                  75                  80

 tgg caa ata caa ctt ttg cag aac cca act gtg tca ttt gaa ggc cca      288
 Trp Gln Ile Gln Leu Leu Gln Asn Pro Thr Val Ser Phe Glu Gly Pro
                  85                  90                  95

 tct tcc ctg ggg gac ggc atc tca tct cct acc cta gaa gaa cct cac      336
 Ser Ser Leu Gly Asp Gly Ile Ser Ser Pro Thr Leu Glu Glu Pro His
             100                 105                 110

 aaa agc cag tct cat ttg gga aac ctg cca aat cct ggt gag atg ctg      384
 Lys Ser Gln Ser His Leu Gly Asn Leu Pro Asn Pro Gly Glu Met Leu
         115                 120                 125

 gat gat gtg tgt ctt caa aat ctc aat cag tca act gtc ttt ccc aac      432
 Asp Asp Val Cys Leu Gln Asn Leu Asn Gln Ser Thr Val Phe Pro Asn
     130                 135                 140

 aga gag ctg agg gag cag cga gag gca ggg gaa gag gac cgg agc ctg      480
 Arg Glu Leu Arg Glu Gln Arg Glu Ala Gly Glu Glu Asp Arg Ser Leu
 145                 150                 155                 160

 agg aac cca cgc aga cac ctc cag gga tgg gtg ctt ccc tct ccc ctc      528
 Arg Asn Pro Arg Arg His Leu Gln Gly Trp Val Leu Pro Ser Pro Leu
                 165                 170                 175

 agt ccc tct cct gtg ctc ttc cat gga gcc agc gca gag cat gct gat      576
 Ser Pro Ser Pro Val Leu Phe His Gly Ala Ser Ala Glu His Ala Asp
             180                 185                 190

 aaa acg cac cca gca ggc aac agg tgg cat cac tgc tgg cag act ctg      624
 Lys Thr His Pro Ala Gly Asn Arg Trp His His Cys Trp Gln Thr Leu
         195                 200                 205

 gag gct ttt gcc atc aca aat gaa aac gaa ggc aga tgc tat cag tca      672
 Glu Ala Phe Ala Ile Thr Asn Glu Asn Glu Gly Arg Cys Tyr Gln Ser
     210                 215                 220

 gaa gca aga aga gaa agg tgt gag gac aac atg aga ggg tgc cgc agg      720
 Glu Ala Arg Arg Glu Arg Cys Glu Asp Asn Met Arg Gly Cys Arg Arg
 225                 230                 235                 240

 act gtc cct gtc cag gtg cta gag ata aaa agg tta cca agc cag aaa      768
 Thr Val Pro Val Gln Val Leu Glu Ile Lys Arg Leu Pro Ser Gln Lys
                 245                 250                 255

 tat tgt tac gat gca aaa cgt ggc cca aac ctc cta tct ccg acc cca      816
 Tyr Cys Tyr Asp Ala Lys Arg Gly Pro Asn Leu Leu Ser Pro Thr Pro
             260                 265                 270

 gcc aag ctg ctc tat tgg tgc ttg atg gga ggc aag aga atc ata ctg      864
 Ala Lys Leu Leu Tyr Trp Cys Leu Met Gly Gly Lys Arg Ile Ile Leu
         275                 280                 285

 acc agg agt cca ggg acc tgg gat cta gtc ctg gct ctg cac ttg tgc      912
 Thr Arg Ser Pro Gly Thr Trp Asp Leu Val Leu Ala Leu His Leu Cys
     290                 295                 300

 ctg ggc aac act cgt ctg gct ggt gaa gcc aag agc aca gcc aca cgg      960
 Leu Gly Asn Thr Arg Leu Ala Gly Glu Ala Lys Ser Thr Ala Thr Arg
 305                 310                 315                 320

 ctg ttt ctc atc ctg gca ccc cca gcc cca gca cag cac ccc aca gag     1008
 Leu Phe Leu Ile Leu Ala Pro Pro Ala Pro Ala Gln His Pro Thr Glu
                 325                 330                 335

 cat gct gga tgc gtt cag taa                                         1029
 His Ala Gly Cys Val Gln 
             340





      <210> 588
      <211> 582
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(582)

      <400> 588
  atg tgg act ata ttt gga tgg att ttg gaa tta ttg ctg acc gga ctt      48
  Met Trp Thr Ile Phe Gly Trp Ile Leu Glu Leu Leu Leu Thr Gly Leu
    1               5                  10                  15

 gct aat gaa tta gat gtg aaa gtt aag aag gaa aca agc aaa gaa atc       96
 Ala Asn Glu Leu Asp Val Lys Val Lys Lys Glu Thr Ser Lys Glu Ile
              20                  25                  30

 tcc aaa gga cca caa aaa ccc ctg ggc tat cag ttt tgt cca ctt caa      144
 Ser Lys Gly Pro Gln Lys Pro Leu Gly Tyr Gln Phe Cys Pro Leu Gln
          35                  40                  45

 gct gta ggg gga ggg gag ttt ggc cta acc agg gta cat gtc ccc ttc      192
 Ala Val Gly Gly Gly Glu Phe Gly Leu Thr Arg Val His Val Pro Phe
      50                  55                  60

 tcc ttc tct gat tta aag cag atc aag gca gac ctg ggg aag ttt tca      240
 Ser Phe Ser Asp Leu Lys Gln Ile Lys Ala Asp Leu Gly Lys Phe Ser
  65                  70                  75                  80

 gaa gat cct gat agt tat ata gat gtc cta cat ggt cta ggg caa aac      288
 Glu Asp Pro Asp Ser Tyr Ile Asp Val Leu His Gly Leu Gly Gln Asn
                  85                  90                  95

 ttc gat ctc act tgg aga gat gtc atg cta ctg tta gat caa acc ctg      336
 Phe Asp Leu Thr Trp Arg Asp Val Met Leu Leu Leu Asp Gln Thr Leu
             100                 105                 110

 gcc ttt aat gaa aag aat gta gct tta gct gca gcc cga gag ttt gga      384
 Ala Phe Asn Glu Lys Asn Val Ala Leu Ala Ala Ala Arg Glu Phe Gly
         115                 120                 125

 gat acc tgg tat ctt agt caa gta aat gat aga atg aca gcc aaa gaa      432
 Asp Thr Trp Tyr Leu Ser Gln Val Asn Asp Arg Met Thr Ala Lys Glu
     130                 135                 140

 agg gac aaa ttc cct act ggt cag caa gcc atc ctc agt atg gat tcc      480
 Arg Asp Lys Phe Pro Thr Gly Gln Gln Ala Ile Leu Ser Met Asp Ser
 145                 150                 155                 160

 cac tgg gac ctc gac tca gat cat ggg gac tgg agt cgc aaa cat ctg      528
 His Trp Asp Leu Asp Ser Asp His Gly Asp Trp Ser Arg Lys His Leu
                 165                 170                 175

 ttg acc tgt gtt cta gaa gga cta aga ata att agg gaa aag gcc atg      576
 Leu Thr Cys Val Leu Glu Gly Leu Arg Ile Ile Arg Glu Lys Ala Met
             180                 185                 190

 aat tag                                                              582
 Asn 






      <210> 589
      <211> 636
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(636)

      <400> 589
  atg gac aca agt ccc ctg tgt ttc tcc att ctg ttg gtt tta tgc atc      48
  Met Asp Thr Ser Pro Leu Cys Phe Ser Ile Leu Leu Val Leu Cys Ile
    1               5                  10                  15

 ttt atc caa tca agt gcc ctt gga caa agc ctg aaa cca ggt cta gga       96
 Phe Ile Gln Ser Ser Ala Leu Gly Gln Ser Leu Lys Pro Gly Leu Gly
              20                  25                  30

 att att cca cag ttg ggc act ctt ggt gta tta ttg ttc atg ccc tgg      144
 Ile Ile Pro Gln Leu Gly Thr Leu Gly Val Leu Leu Phe Met Pro Trp
          35                  40                  45

 ccc cca cct ttg tgc cgc ata gag gga ctc ccc ttc ctg agg tta atg      192
 Pro Pro Pro Leu Cys Arg Ile Glu Gly Leu Pro Phe Leu Arg Leu Met
      50                  55                  60

 att ggg aag gtg tta aag cag gaa gaa ctg caa gaa ggc act cgg gct      240
 Ile Gly Lys Val Leu Lys Gln Glu Glu Leu Gln Glu Gly Thr Arg Ala
  65                  70                  75                  80

 cct ggc aca gcg gaa ata aac cat ggg tcc ctg agg gag act ctg ggt      288
 Pro Gly Thr Ala Glu Ile Asn His Gly Ser Leu Arg Glu Thr Leu Gly
                  85                  90                  95

 gag aaa aga gac cca gat ttg gag ttg aaa gac ctg ggc ctg agt ccc      336
 Glu Lys Arg Asp Pro Asp Leu Glu Leu Lys Asp Leu Gly Leu Ser Pro
             100                 105                 110

 agc tcc atc act tcc cag cac gtg gcc ttg aac aaa tca ctc aag gcc      384
 Ser Ser Ile Thr Ser Gln His Val Ala Leu Asn Lys Ser Leu Lys Ala
         115                 120                 125

 tgc aga cct cgg tca gtc att agt aaa gag aag att act att ata gag      432
 Cys Arg Pro Arg Ser Val Ile Ser Lys Glu Lys Ile Thr Ile Ile Glu
     130                 135                 140

 acc cca ctg ggc tgt ttt gag ggt gaa atg aga cca cat ggc tac tca      480
 Thr Pro Leu Gly Cys Phe Glu Gly Glu Met Arg Pro His Gly Tyr Ser
 145                 150                 155                 160

 gac gcc agt ctg cga gca ccc cac gct cag ctg ctc cat gct tca gcc      528
 Asp Ala Ser Leu Arg Ala Pro His Ala Gln Leu Leu His Ala Ser Ala
                 165                 170                 175

 acc atg caa ccc atc tgg ata atg gac tgt tat gaa gca tgt tgg cag      576
 Thr Met Gln Pro Ile Trp Ile Met Asp Cys Tyr Glu Ala Cys Trp Gln
             180                 185                 190

 cca tcg att agg act aaa ctc tat gct cat tgg gtt gta ttt gca agg      624
 Pro Ser Ile Arg Thr Lys Leu Tyr Ala His Trp Val Val Phe Ala Arg
         195                 200                 205

 atg ctc tgc taa                                                      636
 Met Leu Cys 
     210





      <210> 590
      <211> 675
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(675)

      <400> 590
  atg ggg gca gat ccc ttg tgg ctt ggt gct gtc ctc aca ata gtg aga      48
  Met Gly Ala Asp Pro Leu Trp Leu Gly Ala Val Leu Thr Ile Val Arg
    1               5                  10                  15

 ctg aaa gag gtg tcc cca ctg cct cta aat ctc aaa cgt tta tac aaa       96
 Leu Lys Glu Val Ser Pro Leu Pro Leu Asn Leu Lys Arg Leu Tyr Lys
              20                  25                  30

 gag aca ctg gaa att gaa ccc atc ttg ata att att tct ccg ggt gct      144
 Glu Thr Leu Glu Ile Glu Pro Ile Leu Ile Ile Ile Ser Pro Gly Ala
          35                  40                  45

 gat cct tct cag gaa ctt caa gaa cta gct aat gct gaa aga agc gga      192
 Asp Pro Ser Gln Glu Leu Gln Glu Leu Ala Asn Ala Glu Arg Ser Gly
      50                  55                  60

 gag tgt tat cac cag gtt gcc atg ggt caa ggt caa gct gat tta gca      240
 Glu Cys Tyr His Gln Val Ala Met Gly Gln Gly Gln Ala Asp Leu Ala
  65                  70                  75                  80

 att caa atg cta aaa gaa tgt gcc cgc aat gga gac tgg ctc tgt ttg      288
 Ile Gln Met Leu Lys Glu Cys Ala Arg Asn Gly Asp Trp Leu Cys Leu
                  85                  90                  95

 aag aac tta cat ctt gtg gta tct tgg ctg cca gtt ctg gaa aag tca      336
 Lys Asn Leu His Leu Val Val Ser Trp Leu Pro Val Leu Glu Lys Ser
             100                 105                 110

 cct cca ggt tta aag aag aat tta atg cgt act tat gag tct tgg act      384
 Pro Pro Gly Leu Lys Lys Asn Leu Met Arg Thr Tyr Glu Ser Trp Thr
         115                 120                 125

 cct gag caa att agc aaa aaa gat aat aca cat cga gct cat gct ctc      432
 Pro Glu Gln Ile Ser Lys Lys Asp Asn Thr His Arg Ala His Ala Leu
     130                 135                 140

 ttc agt ctt gca tgg ttt cat gct gca tgt caa gaa aga aga aac tat      480
 Phe Ser Leu Ala Trp Phe His Ala Ala Cys Gln Glu Arg Arg Asn Tyr
 145                 150                 155                 160

 att cct cag atg agg ata tcc cct cat gag ccc aca cca cca ggg cct      528
 Ile Pro Gln Met Arg Ile Ser Pro His Glu Pro Thr Pro Pro Gly Pro
                 165                 170                 175

 tgg gtc cga aac aca gag ctg tgt gga gtc tgc aca gca gct gct cag      576
 Trp Val Arg Asn Thr Glu Leu Cys Gly Val Cys Thr Ala Ala Ala Gln
             180                 185                 190

 agc ttc cag agg aag gag cag gct gcc atc tct gct gtt tca cag cct      624
 Ser Phe Gln Arg Lys Glu Gln Ala Ala Ile Ser Ala Val Ser Gln Pro
         195                 200                 205

 tca ctg gtg atg cct cca gat aca gga aaa atc aag gca act agg gtc      672
 Ser Leu Val Met Pro Pro Asp Thr Gly Lys Ile Lys Ala Thr Arg Val
     210                 215                 220

 tag                                                                  675
 






      <210> 591
      <211> 753
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(753)

      <400> 591
  atg atg ttg aag ata atg ttg gtt gta gtg atg gta gta ata act cta      48
  Met Met Leu Lys Ile Met Leu Val Val Val Met Val Val Ile Thr Leu
    1               5                  10                  15

 gtg gtg atg gtg ata atg gta gtg gtg gtg ggt gat gat cgt ggt gat       96
 Val Val Met Val Ile Met Val Val Val Val Gly Asp Asp Arg Gly Asp
              20                  25                  30

 gat agt ggc agt ggt gat ggt gga ggt ggt agt ggt gat gat ggc aat      144
 Asp Ser Gly Ser Gly Asp Gly Gly Gly Gly Ser Gly Asp Asp Gly Asn
          35                  40                  45

 agt ggc aga tat cca aca tcc tgt gaa acc cag aga tct tgc tcc agc      192
 Ser Gly Arg Tyr Pro Thr Ser Cys Glu Thr Gln Arg Ser Cys Ser Ser
      50                  55                  60

 cgg att cag aga aat tta gcg gga aag gag agg cca aag gct gaa ccc      240
 Arg Ile Gln Arg Asn Leu Ala Gly Lys Glu Arg Pro Lys Ala Glu Pro
  65                  70                  75                  80

 aat ggt gca agg ttt tac ggt tcg gtc atc ctc tgt cct gac gcc gcg      288
 Asn Gly Ala Arg Phe Tyr Gly Ser Val Ile Leu Cys Pro Asp Ala Ala
                  85                  90                  95

 ggg cca gcg gga gaa gaa agc cag atg gtg tca att aaa tta atg ttt      336
 Gly Pro Ala Gly Glu Glu Ser Gln Met Val Ser Ile Lys Leu Met Phe
             100                 105                 110

 gat tca gga cat gtg tac ttt gga gag ctt cat gag cac ctt gga ctt      384
 Asp Ser Gly His Val Tyr Phe Gly Glu Leu His Glu His Leu Gly Leu
         115                 120                 125

 gcc agc ttt cct caa gca acc cct gta act tgt tgg cac aaa att aac      432
 Ala Ser Phe Pro Gln Ala Thr Pro Val Thr Cys Trp His Lys Ile Asn
     130                 135                 140

 cac aat att cag aca aag cag tac tta cag ggg gca atg ggg cct cca      480
 His Asn Ile Gln Thr Lys Gln Tyr Leu Gln Gly Ala Met Gly Pro Pro
 145                 150                 155                 160

 agg cca tca aag atc aag gtg cca gtt ggg ggc cac tca gca gct cct      528
 Arg Pro Ser Lys Ile Lys Val Pro Val Gly Gly His Ser Ala Ala Pro
                 165                 170                 175

 cag gtg agg att gtc tca gaa ctg aag aat ggt tca aat tgg ccc aag      576
 Gln Val Arg Ile Val Ser Glu Leu Lys Asn Gly Ser Asn Trp Pro Lys
             180                 185                 190

 atg ctg aaa ttt att gca ggg atc act ggg aca gtg tgt agc aat tta      624
 Met Leu Lys Phe Ile Ala Gly Ile Thr Gly Thr Val Cys Ser Asn Leu
         195                 200                 205

 gga ggc ttc tct cta agg gaa tca gta gct gct gca ttt ctc tta att      672
 Gly Gly Phe Ser Leu Arg Glu Ser Val Ala Ala Ala Phe Leu Leu Ile
     210                 215                 220

 gaa acc act ctt tcc ctc cag ctt cga tgg ggc agg ttc tca tat ctg      720
 Glu Thr Thr Leu Ser Leu Gln Leu Arg Trp Gly Arg Phe Ser Tyr Leu
 225                 230                 235                 240

 cgt gct gaa agg cgt tta ttt ggt gta ttc tga                          753
 Arg Ala Glu Arg Arg Leu Phe Gly Val Phe 
                 245                 250





      <210> 592
      <211> 333
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(333)

      <400> 592
  atg gcc atg tcc tct ctt acc tct aga act gta ggt gtg ctg tgc ttt      48
  Met Ala Met Ser Ser Leu Thr Ser Arg Thr Val Gly Val Leu Cys Phe
    1               5                  10                  15

 ggg ctt gga aca ccc cag ctt cag tcc ctc cca cga aca gct tca gtt       96
 Gly Leu Gly Thr Pro Gln Leu Gln Ser Leu Pro Arg Thr Ala Ser Val
              20                  25                  30

 ggt gga ctc cct tta gct gag ctg ccc cat gga agt ttg gaa aaa gag      144
 Gly Gly Leu Pro Leu Ala Glu Leu Pro His Gly Ser Leu Glu Lys Glu
          35                  40                  45

 tgg gtt gtg cat ttg aaa atg ttc cca cac ccc agc cag cct cat ttt      192
 Trp Val Val His Leu Lys Met Phe Pro His Pro Ser Gln Pro His Phe
      50                  55                  60

 tct gat gat ccc tct att cag cca aac tcg cgc tac agt ggg aac act      240
 Ser Asp Asp Pro Ser Ile Gln Pro Asn Ser Arg Tyr Ser Gly Asn Thr
  65                  70                  75                  80

 aac atc aat tcc gtg aga gcc agc tgt ccg ctt ctt cca cgg tgc tca      288
 Asn Ile Asn Ser Val Arg Ala Ser Cys Pro Leu Leu Pro Arg Cys Ser
                  85                  90                  95

 gag agc cac aca gga ctc ctg gaa tcg gag cca gct cgg gcc tga          333
 Glu Ser His Thr Gly Leu Leu Glu Ser Glu Pro Ala Arg Ala 
             100                 105                 110





      <210> 593
      <211> 276
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(276)

      <400> 593
  atg gct gtc aag ttg ctg gtt ttc atc gtg att gtg aac tgt ttg ttt      48
  Met Ala Val Lys Leu Leu Val Phe Ile Val Ile Val Asn Cys Leu Phe
    1               5                  10                  15

 tca agg tta cta cag aac tgg aag aaa ggg gga tgt gaa tgg gac aaa       96
 Ser Arg Leu Leu Gln Asn Trp Lys Lys Gly Gly Cys Glu Trp Asp Lys
              20                  25                  30

 tta tta tac aat gct atg aag ttc act gtt gtt act aag aat cag tca      144
 Leu Leu Tyr Asn Ala Met Lys Phe Thr Val Val Thr Lys Asn Gln Ser
          35                  40                  45

 gtt ttc ttg aat aaa tta ttc ctg gat agc tgt aag cct ttg gtc aat      192
 Val Phe Leu Asn Lys Leu Phe Leu Asp Ser Cys Lys Pro Leu Val Asn
      50                  55                  60

 ttc cag agc cct gaa aaa gtt gat tct gac att tct gtc agt ttt ctc      240
 Phe Gln Ser Pro Glu Lys Val Asp Ser Asp Ile Ser Val Ser Phe Leu
  65                  70                  75                  80

 ttt ttt tta aat gaa aag tac aaa cag tac acc tag                      276
 Phe Phe Leu Asn Glu Lys Tyr Lys Gln Tyr Thr 
                  85                  90





      <210> 594
      <211> 216
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(216)

      <400> 594
  atg ggc gcc acc ttc tgg ctc ctg gtg gga ctt gta agt ccc gtg gtc      48
  Met Gly Ala Thr Phe Trp Leu Leu Val Gly Leu Val Ser Pro Val Val
    1               5                  10                  15

 agt tac ctg att gct ctt acg gac ctg acg ctg gaa atc ctc tct ctc       96
 Ser Tyr Leu Ile Ala Leu Thr Asp Leu Thr Leu Glu Ile Leu Ser Leu
              20                  25                  30

 caa ggt ccc tgc agg aga tgg gac ctg cca cag aga atg ccg caa ggg      144
 Gln Gly Pro Cys Arg Arg Trp Asp Leu Pro Gln Arg Met Pro Gln Gly
          35                  40                  45

 atg ttt ctg ttg gga gct aaa cag agc ttc agc caa atc ctg gaa cgg      192
 Met Phe Leu Leu Gly Ala Lys Gln Ser Phe Ser Gln Ile Leu Glu Arg
      50                  55                  60

 aag ctc ttg gga agc tgc ctg tga                                      216
 Lys Leu Leu Gly Ser Cys Leu 
  65                  70





      <210> 595
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 595
  atg gcc agg aac cga ggt ttt tta tca gca gtg ttt tgt ttc act gcc      48
  Met Ala Arg Asn Arg Gly Phe Leu Ser Ala Val Phe Cys Phe Thr Ala
    1               5                  10                  15

 cca agt gga acc gat gag cgg ggt gct act gtg tgg ttg ccc cca cat       96
 Pro Ser Gly Thr Asp Glu Arg Gly Ala Thr Val Trp Leu Pro Pro His
              20                  25                  30

 ctg act cac ctc agt gcc cag gat ggg agc aaa gca cag gaa acc cac      144
 Leu Thr His Leu Ser Ala Gln Asp Gly Ser Lys Ala Gln Glu Thr His
          35                  40                  45

 tgg aca agg gag gag gtg ttg atc tgt gag ggg cag cca gca acc act      192
 Trp Thr Arg Glu Glu Val Leu Ile Cys Glu Gly Gln Pro Ala Thr Thr
      50                  55                  60

 ctc act gtg ggg aac ttg gca gag gac agc ccc agg tat tca cca gat      240
 Leu Thr Val Gly Asn Leu Ala Glu Asp Ser Pro Arg Tyr Ser Pro Asp
  65                  70                  75                  80

 cga ctg taa                                                          249
 Arg Leu 






      <210> 596
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 596
  atg gca tac ctg agt aag gaa att gat gta gtg gca aag ggt tgg cct      48
  Met Ala Tyr Leu Ser Lys Glu Ile Asp Val Val Ala Lys Gly Trp Pro
    1               5                  10                  15

 cat tgt tta tgg gta gtg gtg gca gta gca gtc tta gta tct gaa gca       96
 His Cys Leu Trp Val Val Val Ala Val Ala Val Leu Val Ser Glu Ala
              20                  25                  30

 gtt aaa ata tta cag gga aga gat ctt act gtg tgg aca tct cac gac      144
 Val Lys Ile Leu Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp
          35                  40                  45

 gtg aat ggc ata ctt act gct aaa gga gac ttg tgt cag aga acc ttt      192
 Val Asn Gly Ile Leu Thr Ala Lys Gly Asp Leu Cys Gln Arg Thr Phe
      50                  55                  60

 gtc tct tcc aga att gaa gct gta aag cta caa ata gtt cct caa atg      240
 Val Ser Ser Arg Ile Glu Ala Val Lys Leu Gln Ile Val Pro Gln Met
  65                  70                  75                  80

 gag ccc cag atg cag ccc atg act aaa atc tac tgc gga tcc ctg gac      288
 Glu Pro Gln Met Gln Pro Met Thr Lys Ile Tyr Cys Gly Ser Leu Asp
                  85                  90                  95

 tgg cct gct agc cca tgc tcc aat gtt aat gac att gaa ggc acc cct      336
 Trp Pro Ala Ser Pro Cys Ser Asn Val Asn Asp Ile Glu Gly Thr Pro
             100                 105                 110

 ccc gag gaa atc tca act gca caa ccc cta cta tgc ccc aat tca gca      384
 Pro Glu Glu Ile Ser Thr Ala Gln Pro Leu Leu Cys Pro Asn Ser Ala
         115                 120                 125

 gga agc agt tag                                                      396
 Gly Ser Ser 
     130





      <210> 597
      <211> 684
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(684)

      <400> 597
  atg agc tac tcc tgc ccg tcc ctg cct tca cca ggg tcc ttt acc tgc      48
  Met Ser Tyr Ser Cys Pro Ser Leu Pro Ser Pro Gly Ser Phe Thr Cys
    1               5                  10                  15

 ctc cta ctt ctg gtg gtg aag cta aag caa act gtt cta cct ggt ttg       96
 Leu Leu Leu Leu Val Val Lys Leu Lys Gln Thr Val Leu Pro Gly Leu
              20                  25                  30

 agg gct tta ggg ctg ggc cgg ggt caa agt ggt cac cag ccc aat tgg      144
 Arg Ala Leu Gly Leu Gly Arg Gly Gln Ser Gly His Gln Pro Asn Trp
          35                  40                  45

 tgg ttt ggc atg ctg gtt cca gag att tgg cct gtt tcc cgc aca ggc      192
 Trp Phe Gly Met Leu Val Pro Glu Ile Trp Pro Val Ser Arg Thr Gly
      50                  55                  60

 agt ggg gcc cag gct gtg gcc gac cac gta gtc caa gtg ctg ttt tgt      240
 Ser Gly Ala Gln Ala Val Ala Asp His Val Val Gln Val Leu Phe Cys
  65                  70                  75                  80

 ttc tca gga agg tct gca gag tgg gag gag ctg tgg gtt ctg ccc aga      288
 Phe Ser Gly Arg Ser Ala Glu Trp Glu Glu Leu Trp Val Leu Pro Arg
                  85                  90                  95

 agg act ttg tgg cag cac aga agt gaa aaa aaa aaa agc agc gag gca      336
 Arg Thr Leu Trp Gln His Arg Ser Glu Lys Lys Lys Ser Ser Glu Ala
             100                 105                 110

 gcg gag gag gat ctg aga aca atg gag gaa caa gtc aga gga act tgg      384
 Ala Glu Glu Asp Leu Arg Thr Met Glu Glu Gln Val Arg Gly Thr Trp
         115                 120                 125

 ggt gag act gtt cag gga ggg agc aaa gga gga gag agg aat gga gca      432
 Gly Glu Thr Val Gln Gly Gly Ser Lys Gly Gly Glu Arg Asn Gly Ala
     130                 135                 140

 act tca gag agt gaa gaa gat aat gag ctg gac tgt gat ccc ctg agg      480
 Thr Ser Glu Ser Glu Glu Asp Asn Glu Leu Asp Cys Asp Pro Leu Arg
 145                 150                 155                 160

 gag agt caa ggg cct cag cat tct gaa cga atg gga tcc cac agc agg      528
 Glu Ser Gln Gly Pro Gln His Ser Glu Arg Met Gly Ser His Ser Arg
                 165                 170                 175

 gcc cca gga tgt gca ttt act cac tgt atc cca gaa gag cct tcc aca      576
 Ala Pro Gly Cys Ala Phe Thr His Cys Ile Pro Glu Glu Pro Ser Thr
             180                 185                 190

 agc aca aga aga aga aaa aca gag ggc aaa gtt cca tct ttg atg aaa      624
 Ser Thr Arg Arg Arg Lys Thr Glu Gly Lys Val Pro Ser Leu Met Lys
         195                 200                 205

 ttt agt tta gac cca act aca gca tac gaa gag tat ctg cac tat gcg      672
 Phe Ser Leu Asp Pro Thr Thr Ala Tyr Glu Glu Tyr Leu His Tyr Ala
     210                 215                 220

 gtg aaa ctt tga                                                      684
 Val Lys Leu 
 225





      <210> 598
      <211> 831
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(831)

      <400> 598
  atg gct tat aaa gtg gtc tgg gcc tgc gcg aga gct ctc atg gcg tgg      48
  Met Ala Tyr Lys Val Val Trp Ala Cys Ala Arg Ala Leu Met Ala Trp
    1               5                  10                  15

 ggt gga atc cac att ctg tac aat ggg cac ggg gca gcc ctt cga ggg       96
 Gly Gly Ile His Ile Leu Tyr Asn Gly His Gly Ala Ala Leu Arg Gly
              20                  25                  30

 cat cac cat caa ggg agt gcc ctg gat cct ccg tgc tca tgt cca ctc      144
 His His His Gln Gly Ser Ala Leu Asp Pro Pro Cys Ser Cys Pro Leu
          35                  40                  45

 ctt gcc tct ccc ctc ctc tgc agt gca agg aaa ctc agc cct gtt gcc      192
 Leu Ala Ser Pro Leu Leu Cys Ser Ala Arg Lys Leu Ser Pro Val Ala
      50                  55                  60

 ggt ctt ctc cag gtg ctg aat cag ctg cct ttc gct gag tgg cca gtg      240
 Gly Leu Leu Gln Val Leu Asn Gln Leu Pro Phe Ala Glu Trp Pro Val
  65                  70                  75                  80

 gaa ggt tct gac ccc tcc gac tat gtg gct ttt cct ggt act ccc tcc      288
 Glu Gly Ser Asp Pro Ser Asp Tyr Val Ala Phe Pro Gly Thr Pro Ser
                  85                  90                  95

 ctc ttg ggc gcc caa gct cct tgg att gtt aag gct ggc ggt gct gcc      336
 Leu Leu Gly Ala Gln Ala Pro Trp Ile Val Lys Ala Gly Gly Ala Ala
             100                 105                 110

 caa agc atc ccc ccc agg act tct cga tat gga cag cag agg gca gca      384
 Gln Ser Ile Pro Pro Arg Thr Ser Arg Tyr Gly Gln Gln Arg Ala Ala
         115                 120                 125

 aac tgc cat ttg agg gct cct cac cca gga cga ccc agg ggt ttg aac      432
 Asn Cys His Leu Arg Ala Pro His Pro Gly Arg Pro Arg Gly Leu Asn
     130                 135                 140

 ctg gct tta tcc acg tgg ggt gag agg ggt ggg agg agg gtg gta tta      480
 Leu Ala Leu Ser Thr Trp Gly Glu Arg Gly Gly Arg Arg Val Val Leu
 145                 150                 155                 160

 gtt gtt tgc gtg ttt tta ata att gaa aac cag aaa ccc gac act ctg      528
 Val Val Cys Val Phe Leu Ile Ile Glu Asn Gln Lys Pro Asp Thr Leu
                 165                 170                 175

 agc acc act tca ggt gat gtg ctg tgt ggc att ttc tgc cct tgt gga      576
 Ser Thr Thr Ser Gly Asp Val Leu Cys Gly Ile Phe Cys Pro Cys Gly
             180                 185                 190

 gtc caa cca tcc att ctg aaa cag agc agt tcc ttt gac ctt gac agt      624
 Val Gln Pro Ser Ile Leu Lys Gln Ser Ser Ser Phe Asp Leu Asp Ser
         195                 200                 205

 aca aat tcc tat gcc atg agt act ctt tta agc ttg gac ctg tcc aca      672
 Thr Asn Ser Tyr Ala Met Ser Thr Leu Leu Ser Leu Asp Leu Ser Thr
     210                 215                 220

 gaa gag cca aac ctg aga gtc ctt ggt gat tgg cag gca cag ggg gag      720
 Glu Glu Pro Asn Leu Arg Val Leu Gly Asp Trp Gln Ala Gln Gly Glu
 225                 230                 235                 240

 cgg ccc ttg ctg gtt ggc aca gaa acg gaa cac ctg cag gcc cca gaa      768
 Arg Pro Leu Leu Val Gly Thr Glu Thr Glu His Leu Gln Ala Pro Glu
                 245                 250                 255

 ctg tcc cca gcc cgc tct ctc ctg caa tct tgc act gga tct cac gtt      816
 Leu Ser Pro Ala Arg Ser Leu Leu Gln Ser Cys Thr Gly Ser His Val
             260                 265                 270

 cca gct cag atg tga                                                  831
 Pro Ala Gln Met 
         275





      <210> 599
      <211> 444
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(444)

      <400> 599
  atg gct ctg gcc aga gct gcc att ttg ctg ttg cca ctt gct agt gtt      48
  Met Ala Leu Ala Arg Ala Ala Ile Leu Leu Leu Pro Leu Ala Ser Val
    1               5                  10                  15

 gaa aaa gcc tcc tgc ttc agg ttc act atc agc atg aat gaa gaa aag       96
 Glu Lys Ala Ser Cys Phe Arg Phe Thr Ile Ser Met Asn Glu Glu Lys
              20                  25                  30

 gtg gcc aga ttt cag gct cag atc cag aat ggt gat aag ggt aaa aaa      144
 Val Ala Arg Phe Gln Ala Gln Ile Gln Asn Gly Asp Lys Gly Lys Lys
          35                  40                  45

 cca aac gtc cat aat tct cca aag gca aag ata gag ttt ttc cag tac      192
 Pro Asn Val His Asn Ser Pro Lys Ala Lys Ile Glu Phe Phe Gln Tyr
      50                  55                  60

 aga tgt tac acc aga gac tgg ccc cag cca gtt gcc ttc aat tac caa      240
 Arg Cys Tyr Thr Arg Asp Trp Pro Gln Pro Val Ala Phe Asn Tyr Gln
  65                  70                  75                  80

 cag tct act aga aaa tgg ccg ctg aaa gac cga aaa agt aaa gga ctt      288
 Gln Ser Thr Arg Lys Trp Pro Leu Lys Asp Arg Lys Ser Lys Gly Leu
                  85                  90                  95

 ggt ctc aag cca gtt ggt ggc gcc aga gaa ctc tct gga acc att aaa      336
 Gly Leu Lys Pro Val Gly Gly Ala Arg Glu Leu Ser Gly Thr Ile Lys
             100                 105                 110

 gag atc ctg ggg act gcc cag tct gtg ggc tgt aat gtt gat ggc cac      384
 Glu Ile Leu Gly Thr Ala Gln Ser Val Gly Cys Asn Val Asp Gly His
         115                 120                 125

 tac cct cat gac atc ata gat gac atc aac agt ggt gct gtg gaa tgc      432
 Tyr Pro His Asp Ile Ile Asp Asp Ile Asn Ser Gly Ala Val Glu Cys
     130                 135                 140

 cca gcc agt taa                                                      444
 Pro Ala Ser 
 145





      <210> 600
      <211> 1011
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1011)

      <400> 600
  atg gca gtg gcc act gcg gcg gca gta ctg gcc gct ctg ggc ggg gcg      48
  Met Ala Val Ala Thr Ala Ala Ala Val Leu Ala Ala Leu Gly Gly Ala
    1               5                  10                  15

 ctg tgg ctg gcg gcc cgc cgg ttc gtg ggg ccc agg gtc cag cgg ctg       96
 Leu Trp Leu Ala Ala Arg Arg Phe Val Gly Pro Arg Val Gln Arg Leu
              20                  25                  30

 cgc aga ggc ggg gac ccc ggc ctc atg cac ggg aag act gtg ctg atc      144
 Arg Arg Gly Gly Asp Pro Gly Leu Met His Gly Lys Thr Val Leu Ile
          35                  40                  45

 acc ggg gcg aac agc ggc ctg ggc cgc gcc acg gcc gcc gag cta ctg      192
 Thr Gly Ala Asn Ser Gly Leu Gly Arg Ala Thr Ala Ala Glu Leu Leu
      50                  55                  60

 cgc ctg gga gcg cgg gtg atc atg ggc tgc cgg gac cgc gcg cgc gcc      240
 Arg Leu Gly Ala Arg Val Ile Met Gly Cys Arg Asp Arg Ala Arg Ala
  65                  70                  75                  80

 gag gag gcg gcg ggt cag ctc cgc cgc gag ctc cgc cag gcc gcg gag      288
 Glu Glu Ala Ala Gly Gln Leu Arg Arg Glu Leu Arg Gln Ala Ala Glu
                  85                  90                  95

 tgc ggc cca gag cct ggc gtc agc ggg gtg ggc gag ctc ata gtc cgg      336
 Cys Gly Pro Glu Pro Gly Val Ser Gly Val Gly Glu Leu Ile Val Arg
             100                 105                 110

 gag ctg gac ctc gcc tcg ctg cgc tcg gtg cgc gcc ttc tgc cag gaa      384
 Glu Leu Asp Leu Ala Ser Leu Arg Ser Val Arg Ala Phe Cys Gln Glu
         115                 120                 125

 atg ctc cag gaa gag cct agg ctg gat gtc ttg atc aat aac gca ggg      432
 Met Leu Gln Glu Glu Pro Arg Leu Asp Val Leu Ile Asn Asn Ala Gly
     130                 135                 140

 atc ttc cag tgc cct tac atg aag act gaa gat ggg ttt gag atg cag      480
 Ile Phe Gln Cys Pro Tyr Met Lys Thr Glu Asp Gly Phe Glu Met Gln
 145                 150                 155                 160

 ttc gga gtg aac cat ctg ggg cac ttt cta ctc acc aat ctt ctc ctt      528
 Phe Gly Val Asn His Leu Gly His Phe Leu Leu Thr Asn Leu Leu Leu
                 165                 170                 175

 gga ctc ctc aaa agt tca gct ccc agc agg att gtg gta gtt tct tcc      576
 Gly Leu Leu Lys Ser Ser Ala Pro Ser Arg Ile Val Val Val Ser Ser
             180                 185                 190

 aaa ctt tat aaa tac gga gac atc aat ttt gat gac ttg aac agt gaa      624
 Lys Leu Tyr Lys Tyr Gly Asp Ile Asn Phe Asp Asp Leu Asn Ser Glu
         195                 200                 205

 caa agc tat aat aaa agc ttt tgt tat agc cgg agc aaa ctg gct aac      672
 Gln Ser Tyr Asn Lys Ser Phe Cys Tyr Ser Arg Ser Lys Leu Ala Asn
     210                 215                 220

 att ctt ttt acc agg gaa cta gcc cgc cgc tta gaa ggc aca aat gtc      720
 Ile Leu Phe Thr Arg Glu Leu Ala Arg Arg Leu Glu Gly Thr Asn Val
 225                 230                 235                 240

 acc gtc aat gtg ttg cat cct ggt att gta cgg aca aat ctg ggg agg      768
 Thr Val Asn Val Leu His Pro Gly Ile Val Arg Thr Asn Leu Gly Arg
                 245                 250                 255

 cac ata cac att cca ctg ttg gtc aaa cca ctc ttc aat ttg gtg tca      816
 His Ile His Ile Pro Leu Leu Val Lys Pro Leu Phe Asn Leu Val Ser
             260                 265                 270

 tgg gct ttt ttc aaa act cca gta gaa ggt gcc cag act tcc att tat      864
 Trp Ala Phe Phe Lys Thr Pro Val Glu Gly Ala Gln Thr Ser Ile Tyr
         275                 280                 285

 ttg gcc tct tca cct gag gta gaa gga gtg tca gga aga tac ttt ggg      912
 Leu Ala Ser Ser Pro Glu Val Glu Gly Val Ser Gly Arg Tyr Phe Gly
     290                 295                 300

 gat tgt aaa gag gaa gaa ctg ttg ccc aaa gct atg gat gaa tct gtt      960
 Asp Cys Lys Glu Glu Glu Leu Leu Pro Lys Ala Met Asp Glu Ser Val
 305                 310                 315                 320

 gca aga aaa ctc tgg gat atc agt gaa gtg atg gtt ggc ctg cta aaa     1008
 Ala Arg Lys Leu Trp Asp Ile Ser Glu Val Met Val Gly Leu Leu Lys
                 325                 330                 335

 tag                                                                 1011
 






      <210> 601
      <211> 603
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(603)

      <400> 601
  atg cag gta atg aca ttg ctt tgc ctt gca ttt gta ata gga atc aaa      48
  Met Gln Val Met Thr Leu Leu Cys Leu Ala Phe Val Ile Gly Ile Lys
    1               5                  10                  15

 tct tcg gct aaa gag act cct cca agg tgg aat ttc aaa cat cag aga       96
 Ser Ser Ala Lys Glu Thr Pro Pro Arg Trp Asn Phe Lys His Gln Arg
              20                  25                  30

 aaa ggt cga gga aat ttt agg gat ggg aga gtt cag gtt ctt tat tgt      144
 Lys Gly Arg Gly Asn Phe Arg Asp Gly Arg Val Gln Val Leu Tyr Cys
          35                  40                  45

 aaa gtt ggt gtt tgg tcc tta gat ttt cag gcc aca gaa gcc cag ttc      192
 Lys Val Gly Val Trp Ser Leu Asp Phe Gln Ala Thr Glu Ala Gln Phe
      50                  55                  60

 tac cca caa ata aag gta cta ggg ccc tcc tcc ttc acc tca cca gac      240
 Tyr Pro Gln Ile Lys Val Leu Gly Pro Ser Ser Phe Thr Ser Pro Asp
  65                  70                  75                  80

 atc ttg act tta aac ttc ctc act atc ttg gac gtc ttt gat gct ttc      288
 Ile Leu Thr Leu Asn Phe Leu Thr Ile Leu Asp Val Phe Asp Ala Phe
                  85                  90                  95

 aaa gat cca cca aac atc atc agg gat gga aga ccg gtg ttc aga ctc      336
 Lys Asp Pro Pro Asn Ile Ile Arg Asp Gly Arg Pro Val Phe Arg Leu
             100                 105                 110

 tca caa tca ggg cag cta gaa ttt ctg ctg gaa gtg ggg gtg ctg aaa      384
 Ser Gln Ser Gly Gln Leu Glu Phe Leu Leu Glu Val Gly Val Leu Lys
         115                 120                 125

 gtc aca aag cta gct gac agc agc agc agc agc agc agc agg act gaa      432
 Val Thr Lys Leu Ala Asp Ser Ser Ser Ser Ser Ser Ser Arg Thr Glu
     130                 135                 140

 gaa cct gcc cac atg ccc aac cca ctg ccg cca ata cta gca tct gaa      480
 Glu Pro Ala His Met Pro Asn Pro Leu Pro Pro Ile Leu Ala Ser Glu
 145                 150                 155                 160

 caa gcc acc ctg gag gcc caa gaa tca gcc tgc ctg gac ctg ctg aca      528
 Gln Ala Thr Leu Glu Ala Gln Glu Ser Ala Cys Leu Asp Leu Leu Thr
                 165                 170                 175

 ctg gtg aca gtg gac acc atc ctg ggg tcc aag aac agg gat gct tgg      576
 Leu Val Thr Val Asp Thr Ile Leu Gly Ser Lys Asn Arg Asp Ala Trp
             180                 185                 190

 ccc tcc act gcc acc act gga ggc tga                                  603
 Pro Ser Thr Ala Thr Thr Gly Gly 
         195                 200





      <210> 602
      <211> 768
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(768)

      <400> 602
  atg tta ctt ttc aca aaa tcg tca tgg caa ctg agt ctg tgc aat gca      48
  Met Leu Leu Phe Thr Lys Ser Ser Trp Gln Leu Ser Leu Cys Asn Ala
    1               5                  10                  15

 ttc gag agc act tta tca cct aaa tac agc tat tgg gga acc ggg gtg       96
 Phe Glu Ser Thr Leu Ser Pro Lys Tyr Ser Tyr Trp Gly Thr Gly Val
              20                  25                  30

 tcc ggc gac tcc agt cac tcc ctg gcc acc gcc agc agg agt aac tcg      144
 Ser Gly Asp Ser Ser His Ser Leu Ala Thr Ala Ser Arg Ser Asn Ser
          35                  40                  45

 gcg ctg agc tgc ggg tac gct ctg ggc gtg gcg gac gcg gca ggc tct      192
 Ala Leu Ser Cys Gly Tyr Ala Leu Gly Val Ala Asp Ala Ala Gly Ser
      50                  55                  60

 gca ggc ggc gcc ttg tgg cag agg gaa ggc atc gct cac cgc cgc tgc      240
 Ala Gly Gly Ala Leu Trp Gln Arg Glu Gly Ile Ala His Arg Arg Cys
  65                  70                  75                  80

 cga tgg gtt cat gga tct gtc ctg aga gga gga cga ggt gtc tcc aat      288
 Arg Trp Val His Gly Ser Val Leu Arg Gly Gly Arg Gly Val Ser Asn
                  85                  90                  95

 gcc aag ctt cgg cag cag aag cag cag cca cag cgt aca caa aag ccc      336
 Ala Lys Leu Arg Gln Gln Lys Gln Gln Pro Gln Arg Thr Gln Lys Pro
             100                 105                 110

 gaa ctg ttg gga ggc gga ggg tgg agg gat cct gag aga ggg act gcg      384
 Glu Leu Leu Gly Gly Gly Gly Trp Arg Asp Pro Glu Arg Gly Thr Ala
         115                 120                 125

 gcc gga tgc cca gct gtc gga gcc ccg gcc aga cag ggc cac cag agg      432
 Ala Gly Cys Pro Ala Val Gly Ala Pro Ala Arg Gln Gly His Gln Arg
     130                 135                 140

 gct cct tgg tct agc cgt aat gcc agc gtc tgg gaa gat gcc att gcc      480
 Ala Pro Trp Ser Ser Arg Asn Ala Ser Val Trp Glu Asp Ala Ile Ala
 145                 150                 155                 160

 aag cgg acg tgg tgt agc ggt agc atc tgt gtc aag gaa aaa cac cca      528
 Lys Arg Thr Trp Cys Ser Gly Ser Ile Cys Val Lys Glu Lys His Pro
                 165                 170                 175

 cta ctt agc aga cca gga aag gga gtc tcc ctt tcc cca ggg gag ttt      576
 Leu Leu Ser Arg Pro Gly Lys Gly Val Ser Leu Ser Pro Gly Glu Phe
             180                 185                 190

 aga gaa gac tct act cct cca cct ctt gtg cct gca gtt atc cgg agg      624
 Arg Glu Asp Ser Thr Pro Pro Pro Leu Val Pro Ala Val Ile Arg Arg
         195                 200                 205

 cct atc ctt ctc cct gtg atg ctg tgc ttc agt ggt cat gct tct agt      672
 Pro Ile Leu Leu Pro Val Met Leu Cys Phe Ser Gly His Ala Ser Ser
     210                 215                 220

 cca ctt tca tat acc atc ctg tac acc tgg ctc tgc ctt tta gat agc      720
 Pro Leu Ser Tyr Thr Ile Leu Tyr Thr Trp Leu Cys Leu Leu Asp Ser
 225                 230                 235                 240

 act agc aaa tta gtg aaa gta cta aaa gtc tct gat atg cag aaa taa      768
 Thr Ser Lys Leu Val Lys Val Leu Lys Val Ser Asp Met Gln Lys 
                 245                 250                 255





      <210> 603
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 603
  atg aaa ggc aac agt gaa cag tgt ttg ctg ctc tgt aca ctc gga cga      48
  Met Lys Gly Asn Ser Glu Gln Cys Leu Leu Leu Cys Thr Leu Gly Arg
    1               5                  10                  15

 act gtg gtt gct act ctg tac act cgg acg aac tgt ggt tgc tgt ctt       96
 Thr Val Val Ala Thr Leu Tyr Thr Arg Thr Asn Cys Gly Cys Cys Leu
              20                  25                  30

 caa gga gat gaa cag ctt atc tgc att gaa cgt ctg ctg agg cag gta      144
 Gln Gly Asp Glu Gln Leu Ile Cys Ile Glu Arg Leu Leu Arg Gln Val
          35                  40                  45

 gcc tgc ctc tta gat gag ctc tgc aca gat ctt agg gaa gac ctt aac      192
 Ala Cys Leu Leu Asp Glu Leu Cys Thr Asp Leu Arg Glu Asp Leu Asn
      50                  55                  60

 agt tac agg tca tgt ggt gac ctg atc att cac agt cat att gta taa      240
 Ser Tyr Arg Ser Cys Gly Asp Leu Ile Ile His Ser His Ile Val 
  65                  70                  75





      <210> 604
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 604
  atg ctc ctt gtg gtc ctg gga cca ggg ata gga ctc cag ctg agc ctg      48
  Met Leu Leu Val Val Leu Gly Pro Gly Ile Gly Leu Gln Leu Ser Leu
    1               5                  10                  15

 gtg gaa gag gtc cac gtc cta gcc caa cgg aga gcc atg cag ctg agc       96
 Val Glu Glu Val His Val Leu Ala Gln Arg Arg Ala Met Gln Leu Ser
              20                  25                  30

 ttg ggc gat gtg gtc cac gtg gtt gtt tct gag tgt gtc ctg agg ttg      144
 Leu Gly Asp Val Val His Val Val Val Ser Glu Cys Val Leu Arg Leu
          35                  40                  45

 ctg gat ggc ttg cag ttc cct atg cag atc caa tgc ttc ttt tgc ttt      192
 Leu Asp Gly Leu Gln Phe Pro Met Gln Ile Gln Cys Phe Phe Cys Phe
      50                  55                  60

 ttt ggt tct gca acc tgg aat tta tat gtt caa gat gga gcc atc tca      240
 Phe Gly Ser Ala Thr Trp Asn Leu Tyr Val Gln Asp Gly Ala Ile Ser
  65                  70                  75                  80

 gcc atg aca aca gag aat gta cca ctc tca cat gag gaa gag gga gta      288
 Ala Met Thr Thr Glu Asn Val Pro Leu Ser His Glu Glu Glu Gly Val
                  85                  90                  95

 gga gtc act gaa att cag att act gca tat gct gct gct gct tct ctg      336
 Gly Val Thr Glu Ile Gln Ile Thr Ala Tyr Ala Ala Ala Ala Ser Leu
             100                 105                 110

 ggt ctg gct acc cag tgg ggc tgc cgc aca cca tgc tgg tgc tca aga      384
 Gly Leu Ala Thr Gln Trp Gly Cys Arg Thr Pro Cys Trp Cys Ser Arg
         115                 120                 125

 atg tct gca atg gat cca gtg ata taa                                  411
 Met Ser Ala Met Asp Pro Val Ile 
     130                 135





      <210> 605
      <211> 285
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(285)

      <400> 605
  atg tgg tgg gct gac atc ctg gga ctg ctg ctc ctg aca tgc cta gtc      48
  Met Trp Trp Ala Asp Ile Leu Gly Leu Leu Leu Leu Thr Cys Leu Val
    1               5                  10                  15

 cac tgc atg caa ata aaa tcg gat gcc cag agc agc cga ttg cct aat       96
 His Cys Met Gln Ile Lys Ser Asp Ala Gln Ser Ser Arg Leu Pro Asn
              20                  25                  30

 gct caa tat tgg gag gaa aga aac aaa gaa tct aaa gca aat caa gtc      144
 Ala Gln Tyr Trp Glu Glu Arg Asn Lys Glu Ser Lys Ala Asn Gln Val
          35                  40                  45

 aat atg ctc ccc tgg aaa aaa aga gta tgc tac cag gag ttc tat gcc      192
 Asn Met Leu Pro Trp Lys Lys Arg Val Cys Tyr Gln Glu Phe Tyr Ala
      50                  55                  60

 agt ggc agc att gaa gtg cac aga gtc tca cac tgg caa cac ctg gat      240
 Ser Gly Ser Ile Glu Val His Arg Val Ser His Trp Gln His Leu Asp
  65                  70                  75                  80

 ttg gga gag gcc aca ttc aaa cag cag cag cag cag cag cag tag          285
 Leu Gly Glu Ala Thr Phe Lys Gln Gln Gln Gln Gln Gln Gln 
                  85                  90





      <210> 606
      <211> 723
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(723)

      <400> 606
  atg gcc gtg ttt atc tcc agg tgt gca ctg act gcc tcg cta gct tgt      48
  Met Ala Val Phe Ile Ser Arg Cys Ala Leu Thr Ala Ser Leu Ala Cys
    1               5                  10                  15

 tcg ttc act ctg ttg gca gtt tcc cca gtc atc tct gag gcc ccc atc       96
 Ser Phe Thr Leu Leu Ala Val Ser Pro Val Ile Ser Glu Ala Pro Ile
              20                  25                  30

 tac cta gcc tac tta gag agt atg cgt tca ggc cag gac ctg agc ttc      144
 Tyr Leu Ala Tyr Leu Glu Ser Met Arg Ser Gly Gln Asp Leu Ser Phe
          35                  40                  45

 ttc atg gga tca gag cag cgt gct ggg ccc agt gca ggc aat gcc tta      192
 Phe Met Gly Ser Glu Gln Arg Ala Gly Pro Ser Ala Gly Asn Ala Leu
      50                  55                  60

 atg gat gct atc gaa gtt gcc atg gat cag gtg cca gga gag gag acg      240
 Met Asp Ala Ile Glu Val Ala Met Asp Gln Val Pro Gly Glu Glu Thr
  65                  70                  75                  80

 gag gca aag cag ggc cag tca gct ctc cag aga aga cac tct cag agg      288
 Glu Ala Lys Gln Gly Gln Ser Ala Leu Gln Arg Arg His Ser Gln Arg
                  85                  90                  95

 gca gct gca gcc ttg ctc cac tgc aag gct caa gca gaa gct tcc tct      336
 Ala Ala Ala Ala Leu Leu His Cys Lys Ala Gln Ala Glu Ala Ser Ser
             100                 105                 110

 gct gca aaa tgg agc agc cat aag aac cac gat gca gga tct gag ggt      384
 Ala Ala Lys Trp Ser Ser His Lys Asn His Asp Ala Gly Ser Glu Gly
         115                 120                 125

 act ata caa act gcc agt aca aaa ttg cat gtg cac ccc gtt tgc ccc      432
 Thr Ile Gln Thr Ala Ser Thr Lys Leu His Val His Pro Val Cys Pro
     130                 135                 140

 tcc gag gcc cta gcg ata gct tgc tgg aac cgc aca acg cag ttc act      480
 Ser Glu Ala Leu Ala Ile Ala Cys Trp Asn Arg Thr Thr Gln Phe Thr
 145                 150                 155                 160

 gac cga tca tca ccg agg cta aag cca atc ttg ctc atc aaa gtg cca      528
 Asp Arg Ser Ser Pro Arg Leu Lys Pro Ile Leu Leu Ile Lys Val Pro
                 165                 170                 175

 gca aaa ccg gat ttg gtg gcc acg tta agc cag tac gca caa gtt ctt      576
 Ala Lys Pro Asp Leu Val Ala Thr Leu Ser Gln Tyr Ala Gln Val Leu
             180                 185                 190

 ctg atg ggc atc gat gtg tcc tac ttg aag gaa ccc cca cat ttc cac      624
 Leu Met Gly Ile Asp Val Ser Tyr Leu Lys Glu Pro Pro His Phe His
         195                 200                 205

 agg gcc gcg ccc cac gtg gcc acc cct tca ata agc cag gtt tct acc      672
 Arg Ala Ala Pro His Val Ala Thr Pro Ser Ile Ser Gln Val Ser Thr
     210                 215                 220

 acc ctc ctg cct gac cat gcg gcc gct gcc cag gag cca gta aaa acc      720
 Thr Leu Leu Pro Asp His Ala Ala Ala Ala Gln Glu Pro Val Lys Thr
 225                 230                 235                 240

 taa                                                                  723
 






      <210> 607
      <211> 330
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(330)

      <400> 607
  atg tca ctt aca gtg ccg ttc atc act gct atc ccc aca ctg atc tgt      48
  Met Ser Leu Thr Val Pro Phe Ile Thr Ala Ile Pro Thr Leu Ile Cys
    1               5                  10                  15

 gaa gtc aca aat gct gtc agg agg caa gga gac tcc att gtc aca ctg       96
 Glu Val Thr Asn Ala Val Arg Arg Gln Gly Asp Ser Ile Val Thr Leu
              20                  25                  30

 aaa gct ttc tgt ccc ttg ctg agc cag tgt aga att gaa aac aca ggc      144
 Lys Ala Phe Cys Pro Leu Leu Ser Gln Cys Arg Ile Glu Asn Thr Gly
          35                  40                  45

 aat cca aag gca aca aaa agt ttc att cat ggg gaa tgc caa cat tct      192
 Asn Pro Lys Ala Thr Lys Ser Phe Ile His Gly Glu Cys Gln His Ser
      50                  55                  60

 gtc cag gaa gaa gag cat tac ttg cac aag aat tca cct gtc aat tca      240
 Val Gln Glu Glu Glu His Tyr Leu His Lys Asn Ser Pro Val Asn Ser
  65                  70                  75                  80

 tca cga ttt act ttt aca agt gaa aca cct gat ttc agg atg cat att      288
 Ser Arg Phe Thr Phe Thr Ser Glu Thr Pro Asp Phe Arg Met His Ile
                  85                  90                  95

 cag aat gaa caa tat att gaa gtt gag atc aca cag aca taa              330
 Gln Asn Glu Gln Tyr Ile Glu Val Glu Ile Thr Gln Thr 
             100                 105





      <210> 608
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 608
  atg ctg cct cct tcc ctt ggc ctc tat caa tcc aat tat ctg gca ctg      48
  Met Leu Pro Pro Ser Leu Gly Leu Tyr Gln Ser Asn Tyr Leu Ala Leu
    1               5                  10                  15

 tgc ttg ctc tat acc tgc tac gct gct cca agt aga gat gtc tac tct       96
 Cys Leu Leu Tyr Thr Cys Tyr Ala Ala Pro Ser Arg Asp Val Tyr Ser
              20                  25                  30

 agg agt ctt cca gaa cta aca tca gaa ttg tct gaa tca tca gaa acg      144
 Arg Ser Leu Pro Glu Leu Thr Ser Glu Leu Ser Glu Ser Ser Glu Thr
          35                  40                  45

 tct att tcg gaa aaa tcg gat tca tca aat gaa tct tcg gcc aag aac      192
 Ser Ile Ser Glu Lys Ser Asp Ser Ser Asn Glu Ser Ser Ala Lys Asn
      50                  55                  60

 tct tcg aga atg atg tta aca tca cgc gta gga atg tta cgt ttt cta      240
 Ser Ser Arg Met Met Leu Thr Ser Arg Val Gly Met Leu Arg Phe Leu
  65                  70                  75                  80

 gga ctt gac att tta agt gat tga                                      264
 Gly Leu Asp Ile Leu Ser Asp 
                  85





      <210> 609
      <211> 141
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(141)

      <400> 609
  atg tgg aac ttg cct ccc tat tct gtg atc tta aaa gtg tac acc ctt      48
  Met Trp Asn Leu Pro Pro Tyr Ser Val Ile Leu Lys Val Tyr Thr Leu
    1               5                  10                  15

 gcc aca acc ata gca ttt gct cag tac tct caa cat aaa cca agc tta       96
 Ala Thr Thr Ile Ala Phe Ala Gln Tyr Ser Gln His Lys Pro Ser Leu
              20                  25                  30

 gat cgc aat gaa act gcg gac ctg cag gct gcc ttg ctt cac tga          141
 Asp Arg Asn Glu Thr Ala Asp Leu Gln Ala Ala Leu Leu His 
          35                  40                  45





      <210> 610
      <211> 255
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(255)

      <400> 610
  atg act cgg tcg cgg tcg ctg agg gcc gca ata ttg gcg ccg cgg ctg      48
  Met Thr Arg Ser Arg Ser Leu Arg Ala Ala Ile Leu Ala Pro Arg Leu
    1               5                  10                  15

 cgc ctg ctc ctc ggc tgg cag ccg ctc cac tcc ggc tac agc ccc ggc       96
 Arg Leu Leu Leu Gly Trp Gln Pro Leu His Ser Gly Tyr Ser Pro Gly
              20                  25                  30

 tcc ttc cta ctc ccc ggg ccc ggc acc gcc act tcc gcc tcc gcc ccc      144
 Ser Phe Leu Leu Pro Gly Pro Gly Thr Ala Thr Ser Ala Ser Ala Pro
          35                  40                  45

 ctc cgg cgc gac ccg ctc cgg cag ctg gat acc agg cga cgc ttt ccg      192
 Leu Arg Arg Asp Pro Leu Arg Gln Leu Asp Thr Arg Arg Arg Phe Pro
      50                  55                  60

 aag ggc ggg att ggc gga ctc gcg ggc agg ggg cgg gac aag agg cgc      240
 Lys Gly Gly Ile Gly Gly Leu Ala Gly Arg Gly Arg Asp Lys Arg Arg
  65                  70                  75                  80

 gga ttg gtg gcg tga                                                  255
 Gly Leu Val Ala 






      <210> 611
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 611
  atg cag tgc tgc ctg ctg ctg cgc tgg ctg gca tct gcc ctc ctc cgt      48
  Met Gln Cys Cys Leu Leu Leu Arg Trp Leu Ala Ser Ala Leu Leu Arg
    1               5                  10                  15

 ctc ctg ggt gct gcc aca gag aag aga gag aga gtg aag cgg gca gag       96
 Leu Leu Gly Ala Ala Thr Glu Lys Arg Glu Arg Val Lys Arg Ala Glu
              20                  25                  30

 act ggc tgt tgc cat cac aca act gag ggc gga cct gga gct cag ccg      144
 Thr Gly Cys Cys His His Thr Thr Glu Gly Gly Pro Gly Ala Gln Pro
          35                  40                  45

 gct gag ggt ttg aga gac cgt tgg gag caa gac cca acc aca agg ccc      192
 Ala Glu Gly Leu Arg Asp Arg Trp Glu Gln Asp Pro Thr Thr Arg Pro
      50                  55                  60

 atg gaa gag gaa gtt ggc aga tct cag aaa ggg gag gaa aag gag agg      240
 Met Glu Glu Glu Val Gly Arg Ser Gln Lys Gly Glu Glu Lys Glu Arg
  65                  70                  75                  80

 aaa gga gga gag tta aat gag aaa gga ggg cga gtt gag aag gtt ctg      288
 Lys Gly Gly Glu Leu Asn Glu Lys Gly Gly Arg Val Glu Lys Val Leu
                  85                  90                  95

 agc agt ttc agg tcc acg gtt gag caa tgt tct tcc tgg tca aca aac      336
 Ser Ser Phe Arg Ser Thr Val Glu Gln Cys Ser Ser Trp Ser Thr Asn
             100                 105                 110

 tgc ctg gat ttc att ttg gcc tga                                      360
 Cys Leu Asp Phe Ile Leu Ala 
         115





      <210> 612
      <211> 465
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(465)

      <400> 612
  atg gcc tgc tgg gtc aat ggc ctg ctg gcc tgc cag tgc ctg tcg gtg      48
  Met Ala Cys Trp Val Asn Gly Leu Leu Ala Cys Gln Cys Leu Ser Val
    1               5                  10                  15

 tgc ttt cct gcc agt gtg ctc ctc tgg aag ccc tct gac tac cag ccg       96
 Cys Phe Pro Ala Ser Val Leu Leu Trp Lys Pro Ser Asp Tyr Gln Pro
              20                  25                  30

 ctt gtc tct tct tcc gcg aaa tta act tta gaa aat ccc ttt cta aat      144
 Leu Val Ser Ser Ser Ala Lys Leu Thr Leu Glu Asn Pro Phe Leu Asn
          35                  40                  45

 atg gat tta caa tgc act ggc tcc gaa atg cat tgc tta ttc atc aaa      192
 Met Asp Leu Gln Cys Thr Gly Ser Glu Met His Cys Leu Phe Ile Lys
      50                  55                  60

 gtt ttg cac ttc tgt tct tgt cta tgt cct gag ttg aga aat aga cgg      240
 Val Leu His Phe Cys Ser Cys Leu Cys Pro Glu Leu Arg Asn Arg Arg
  65                  70                  75                  80

 tcc aca gcg gac aac tta gaa tgg aat aag gga gat gtg ttt gag gca      288
 Ser Thr Ala Asp Asn Leu Glu Trp Asn Lys Gly Asp Val Phe Glu Ala
                  85                  90                  95

 cta cca ttg gaa gat gtg ctg ggg aga agc cca gcc cag caa cat gcg      336
 Leu Pro Leu Glu Asp Val Leu Gly Arg Ser Pro Ala Gln Gln His Ala
             100                 105                 110

 gca gga cca cat ctc ggc aga gac ttc ctg ata agc aag agt ctt ggg      384
 Ala Gly Pro His Leu Gly Arg Asp Phe Leu Ile Ser Lys Ser Leu Gly
         115                 120                 125

 gaa ata ggg gaa agg att gaa ata tcc aca aaa gaa tgt ctc att tat      432
 Glu Ile Gly Glu Arg Ile Glu Ile Ser Thr Lys Glu Cys Leu Ile Tyr
     130                 135                 140

 gag ctg atg tta aat ttg cat ctc aca gat tag                          465
 Glu Leu Met Leu Asn Leu His Leu Thr Asp 
 145                 150





      <210> 613
      <211> 153
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(153)

      <400> 613
  atg cag tgg ata aca gta att gtg cac ttt cag tgc ctt cta cct ccc      48
  Met Gln Trp Ile Thr Val Ile Val His Phe Gln Cys Leu Leu Pro Pro
    1               5                  10                  15

 tct acc aag tat gaa ctg cat gca tgg ctg att tat gat ttc ggc tat       96
 Ser Thr Lys Tyr Glu Leu His Ala Trp Leu Ile Tyr Asp Phe Gly Tyr
              20                  25                  30

 tat cgc ttc atg tgc gtt gtt cac tat ttt gta act gtt att aaa gta      144
 Tyr Arg Phe Met Cys Val Val His Tyr Phe Val Thr Val Ile Lys Val
          35                  40                  45

 aaa tac tga                                                          153
 Lys Tyr 
      50





      <210> 614
      <211> 474
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(474)

      <400> 614
  atg gcc ggc cac agc ctg ttt ttg gaa ata aag ttt tac tgg aac aca      48
  Met Ala Gly His Ser Leu Phe Leu Glu Ile Lys Phe Tyr Trp Asn Thr
    1               5                  10                  15

 gcc aca ctc att tgt tta ctt att gtc tat ggc tgc ttt cat cct aca       96
 Ala Thr Leu Ile Cys Leu Leu Ile Val Tyr Gly Cys Phe His Pro Thr
              20                  25                  30

 agg gcc gag ctg agc agc tgt gac ata gcc agg tgg cct gca aaa cct      144
 Arg Ala Glu Leu Ser Ser Cys Asp Ile Ala Arg Trp Pro Ala Lys Pro
          35                  40                  45

 aaa ata ttt act aat tgg tgc cct aag aac aag ttt gcc aat ccc ctg      192
 Lys Ile Phe Thr Asn Trp Cys Pro Lys Asn Lys Phe Ala Asn Pro Leu
      50                  55                  60

 acc att aga tca tct agt cca tcc tat act gta cag aaa tgc aat acc      240
 Thr Ile Arg Ser Ser Ser Pro Ser Tyr Thr Val Gln Lys Cys Asn Thr
  65                  70                  75                  80

 atc aca tac aca aat aat gct ggg ccc aga gtc tcc aca aag gag gac      288
 Ile Thr Tyr Thr Asn Asn Ala Gly Pro Arg Val Ser Thr Lys Glu Asp
                  85                  90                  95

 ctc act cag cca gac cgc tgg ggc tac cca agc tgt gca gga ttt agg      336
 Leu Thr Gln Pro Asp Arg Trp Gly Tyr Pro Ser Cys Ala Gly Phe Arg
             100                 105                 110

 gca aat aaa agg cta gaa aag gag atg tta gct acc ata ctg gac agt      384
 Ala Asn Lys Arg Leu Glu Lys Glu Met Leu Ala Thr Ile Leu Asp Ser
         115                 120                 125

 aca gag gat gaa aac aac cca cag gct tta ttt gac tca aca ttc agt      432
 Thr Glu Asp Glu Asn Asn Pro Gln Ala Leu Phe Asp Ser Thr Phe Ser
     130                 135                 140

 tcc aca att acc tgt gct gcc tac tgc att caa gag att taa              474
 Ser Thr Ile Thr Cys Ala Ala Tyr Cys Ile Gln Glu Ile 
 145                 150                 155





      <210> 615
      <211> 156
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(156)

      <400> 615
  atg act gtt cag aag gca ctt tca gct ttt ctc ata gtt tta aca tgt      48
  Met Thr Val Gln Lys Ala Leu Ser Ala Phe Leu Ile Val Leu Thr Cys
    1               5                  10                  15

 ggg tct tcc ttc ttg gag gta tgg gaa aaa cag tct aag cct gat gag       96
 Gly Ser Ser Phe Leu Glu Val Trp Glu Lys Gln Ser Lys Pro Asp Glu
              20                  25                  30

 aaa agg ctg tgg att tct cag ctg ttt cgt gag cag gtg cag atg gct      144
 Lys Arg Leu Trp Ile Ser Gln Leu Phe Arg Glu Gln Val Gln Met Ala
          35                  40                  45

 ttc atg aac tga                                                      156
 Phe Met Asn 
      50





      <210> 616
      <211> 252
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(252)

      <400> 616
  atg acc agt att ctg tta ttt att tat gac tgg att cca ggt ctg gtt      48
  Met Thr Ser Ile Leu Leu Phe Ile Tyr Asp Trp Ile Pro Gly Leu Val
    1               5                  10                  15

 gct aca tgt tgg att gct cca gat ctt gtt gct cca cat tgg aag gtt       96
 Ala Thr Cys Trp Ile Ala Pro Asp Leu Val Ala Pro His Trp Lys Val
              20                  25                  30

 ctc agt cgt gtt cac caa gca tca gta gga ata gta gag gta aat cca      144
 Leu Ser Arg Val His Gln Ala Ser Val Gly Ile Val Glu Val Asn Pro
          35                  40                  45

 aca agc aga att gat ggt ttt gct gag atc tgg aca gtc cct atg aat      192
 Thr Ser Arg Ile Asp Gly Phe Ala Glu Ile Trp Thr Val Pro Met Asn
      50                  55                  60

 ccc tta aaa gtc ctc ctc ctt caa tgg tca ctc ttc aca tgc tac agc      240
 Pro Leu Lys Val Leu Leu Leu Gln Trp Ser Leu Phe Thr Cys Tyr Ser
  65                  70                  75                  80

 agg ggt gga tga                                                      252
 Arg Gly Gly 






      <210> 617
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 617
  atg gtc tgc cca gag cca cac cct gcc ctc tgc aag cca cag ccc tgt      48
  Met Val Cys Pro Glu Pro His Pro Ala Leu Cys Lys Pro Gln Pro Cys
    1               5                  10                  15

 tct gta gca ttc ttg gct ctt cat gcc ctg cag aga ttt acc tgg ttg       96
 Ser Val Ala Phe Leu Ala Leu His Ala Leu Gln Arg Phe Thr Trp Leu
              20                  25                  30

 ctg gcc cat gtc acc tgt tcc tgc ttt gtg aca gag aca ctc ttt agt      144
 Leu Ala His Val Thr Cys Ser Cys Phe Val Thr Glu Thr Leu Phe Ser
          35                  40                  45

 gtg gga act gaa tat gca aat gtt tac ctc tca cct cat aag cac cca      192
 Val Gly Thr Glu Tyr Ala Asn Val Tyr Leu Ser Pro His Lys His Pro
      50                  55                  60

 tcc tca cag agg gca gct ggg gac agt cat aac agc aag tct gct gtg      240
 Ser Ser Gln Arg Ala Ala Gly Asp Ser His Asn Ser Lys Ser Ala Val
  65                  70                  75                  80

 gag gtc atc acg agc act gtg gaa gac tca cac ttg tgg aag ggt ttt      288
 Glu Val Ile Thr Ser Thr Val Glu Asp Ser His Leu Trp Lys Gly Phe
                  85                  90                  95

 gga gtg gat gtt tct cat tcc tga                                      312
 Gly Val Asp Val Ser His Ser 
             100





      <210> 618
      <211> 720
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(720)

      <400> 618
  atg gtt tgt atc cta tcg tta tta ata cgg ctg tct cta gat gag caa      48
  Met Val Cys Ile Leu Ser Leu Leu Ile Arg Leu Ser Leu Asp Glu Gln
    1               5                  10                  15

 aca tgc gct ctc act tct tcc cac att caa gaa tgg ggt ccc aaa cga       96
 Thr Cys Ala Leu Thr Ser Ser His Ile Gln Glu Trp Gly Pro Lys Arg
              20                  25                  30

 gag att cga cgt aaa cgt ccg ctc cca act aag ttc tca ggc gct gac      144
 Glu Ile Arg Arg Lys Arg Pro Leu Pro Thr Lys Phe Ser Gly Ala Asp
          35                  40                  45

 aac gac aag aat tcc tca cac aaa cgt agc gct tca atc act aaa ccg      192
 Asn Asp Lys Asn Ser Ser His Lys Arg Ser Ala Ser Ile Thr Lys Pro
      50                  55                  60

 ctt tca cag ccc tcg acc ctg ccg cga gat gtc cgc cgc cca ccg tca      240
 Leu Ser Gln Pro Ser Thr Leu Pro Arg Asp Val Arg Arg Pro Pro Ser
  65                  70                  75                  80

 ggt cac cgc ctc cct aac gac ttc ggc tgc ccg ggc cct gcc cct gaa      288
 Gly His Arg Leu Pro Asn Asp Phe Gly Cys Pro Gly Pro Ala Pro Glu
                  85                  90                  95

 cct cgc acc cct cct gcc tcg ttc agg aag ctc cgc acc tat ccg gcc      336
 Pro Arg Thr Pro Pro Ala Ser Phe Arg Lys Leu Arg Thr Tyr Pro Ala
             100                 105                 110

 gcc acc ctc agc aca gcc acg gca gcc gac tcg gcg ttc cta ctg ccc      384
 Ala Thr Leu Ser Thr Ala Thr Ala Ala Asp Ser Ala Phe Leu Leu Pro
         115                 120                 125

 cgg aag tgc tcc ttc agc gca gag gcg tgc cgg tgt gtc cga gaa aac      432
 Arg Lys Cys Ser Phe Ser Ala Glu Ala Cys Arg Cys Val Arg Glu Asn
     130                 135                 140

 ttc cga gtt aag ccg ccg ctg agg ccg gaa gga gct aga cgg cgg tcg      480
 Phe Arg Val Lys Pro Pro Leu Arg Pro Glu Gly Ala Arg Arg Arg Ser
 145                 150                 155                 160

 ggt gcc ccc ctg ctg ttc cca ctc aaa act ctg cta ggc ctg ctg gct      528
 Gly Ala Pro Leu Leu Phe Pro Leu Lys Thr Leu Leu Gly Leu Leu Ala
                 165                 170                 175

 gtg gaa gag cag ctg ccc gct ctc ctg tcc att cca cga cac aac agc      576
 Val Glu Glu Gln Leu Pro Ala Leu Leu Ser Ile Pro Arg His Asn Ser
             180                 185                 190

 ggc ctc ttg tgg cca tca cca gct cta cag gaa ctg gcc ttt gat cat      624
 Gly Leu Leu Trp Pro Ser Pro Ala Leu Gln Glu Leu Ala Phe Asp His
         195                 200                 205

 cca ccc gtg atg ttc cct gaa agg gga aca ata aat gtt aat tac ctg      672
 Pro Pro Val Met Phe Pro Glu Arg Gly Thr Ile Asn Val Asn Tyr Leu
     210                 215                 220

 cag gtt gtg ttg gct cca ggt ttt cgg cac tgt gcc tac act gaa taa      720
 Gln Val Val Leu Ala Pro Gly Phe Arg His Cys Ala Tyr Thr Glu 
 225                 230                 235





      <210> 619
      <211> 714
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(714)

      <400> 619
  atg gtt cct tcc tca acg ggg agc aaa gtg gcc tat ggg aaa caa tca      48
  Met Val Pro Ser Ser Thr Gly Ser Lys Val Ala Tyr Gly Lys Gln Ser
    1               5                  10                  15

 atg tgc ctc atg gct cta tgc atg tgg gta atg tcc ttt agg gct agt       96
 Met Cys Leu Met Ala Leu Cys Met Trp Val Met Ser Phe Arg Ala Ser
              20                  25                  30

 cca ttt gta ctt gca gcc ctt cac ttg aaa aac caa ggt gga aga cag      144
 Pro Phe Val Leu Ala Ala Leu His Leu Lys Asn Gln Gly Gly Arg Gln
          35                  40                  45

 att tgt ggg aag aag ggt gag aaa gac act gga gac acg gaa acc agt      192
 Ile Cys Gly Lys Lys Gly Glu Lys Asp Thr Gly Asp Thr Glu Thr Ser
      50                  55                  60

 aag agc ctg agg agg cca ttg ttt ata tcc ttg act gca gtt aac cag      240
 Lys Ser Leu Arg Arg Pro Leu Phe Ile Ser Leu Thr Ala Val Asn Gln
  65                  70                  75                  80

 tca gct gcc tac aca cct tcc cac tcc agc aca aac aca acc agg agt      288
 Ser Ala Ala Tyr Thr Pro Ser His Ser Ser Thr Asn Thr Thr Arg Ser
                  85                  90                  95

 aag ggc act gat gcc ttg aca gaa act caa gta tcc agt gga aac tgg      336
 Lys Gly Thr Asp Ala Leu Thr Glu Thr Gln Val Ser Ser Gly Asn Trp
             100                 105                 110

 ggc atg aat gag gca tta tca cat tta gaa gtc caa gct tta gat ttc      384
 Gly Met Asn Glu Ala Leu Ser His Leu Glu Val Gln Ala Leu Asp Phe
         115                 120                 125

 gat tcc gta ggt ttg ggc ttc aag ctc aag ata ctc ccc gca aca gcg      432
 Asp Ser Val Gly Leu Gly Phe Lys Leu Lys Ile Leu Pro Ala Thr Ala
     130                 135                 140

 ggc tgt acc tgc cac tgg caa gtg cca cat ttt aac aac gat gat gat      480
 Gly Cys Thr Cys His Trp Gln Val Pro His Phe Asn Asn Asp Asp Asp
 145                 150                 155                 160

 aac agc aac att tca tct tca cca caa ccc tat atg caa ccc tac caa      528
 Asn Ser Asn Ile Ser Ser Ser Pro Gln Pro Tyr Met Gln Pro Tyr Gln
                 165                 170                 175

 aac cca ggg tca tta ggg ttt gga gca agg tct ata gcg ttc atg tac      576
 Asn Pro Gly Ser Leu Gly Phe Gly Ala Arg Ser Ile Ala Phe Met Tyr
             180                 185                 190

 cat gat gta cag aac aaa agg ttc aag ttc ccc aaa gct gca att acc      624
 His Asp Val Gln Asn Lys Arg Phe Lys Phe Pro Lys Ala Ala Ile Thr
         195                 200                 205

 aga ggt cat aaa aag ctg gcc aat cct ttc aaa tca aag tca gtc aag      672
 Arg Gly His Lys Lys Leu Ala Asn Pro Phe Lys Ser Lys Ser Val Lys
     210                 215                 220

 att cta aga gtt gga atc ctg ctc cta gga aaa cct gtc tga              714
 Ile Leu Arg Val Gly Ile Leu Leu Leu Gly Lys Pro Val 
 225                 230                 235





      <210> 620
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 620
  atg gcg gcc gtg cac tcc ttg ccc aca gct ggc ctt ttc tcc acc ttc      48
  Met Ala Ala Val His Ser Leu Pro Thr Ala Gly Leu Phe Ser Thr Phe
    1               5                  10                  15

 ggt ctc cat cgt aac gcg gct ggc tct ctc ggc gcc ggc tta ggc ctt       96
 Gly Leu His Arg Asn Ala Ala Gly Ser Leu Gly Ala Gly Leu Gly Leu
              20                  25                  30

 gca tgt agg gaa atg ttg cag cga aag tca cgg cag ttg ggg ctg gtg      144
 Ala Cys Arg Glu Met Leu Gln Arg Lys Ser Arg Gln Leu Gly Leu Val
          35                  40                  45

 tca gct gat tta ctg cag tgg cgg cgg cgg cgg cgg cgg cac cgg cac      192
 Ser Ala Asp Leu Leu Gln Trp Arg Arg Arg Arg Arg Arg His Arg His
      50                  55                  60

 ctt gca gta tca ctg ggg aga cgg cgg ctg tat agc gct tgc cgc ccc      240
 Leu Ala Val Ser Leu Gly Arg Arg Arg Leu Tyr Ser Ala Cys Arg Pro
  65                  70                  75                  80

 acg gat tat ccc agc agg atc tac gca ccc cgc atc ctc cgt agt tcc      288
 Thr Asp Tyr Pro Ser Arg Ile Tyr Ala Pro Arg Ile Leu Arg Ser Ser
                  85                  90                  95

 gcc cta tcc ttg tcc tcc ttg gct ggg gcg ccc acc ggc ggt ctg ata      336
 Ala Leu Ser Leu Ser Ser Leu Ala Gly Ala Pro Thr Gly Gly Leu Ile
             100                 105                 110

 ggc tac atc gcg gca tga                                              354
 Gly Tyr Ile Ala Ala 
         115





      <210> 621
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 621
  atg aga aga cag acc gta aac aag cag ggt atc cag gcg ctc tgc ctg      48
  Met Arg Arg Gln Thr Val Asn Lys Gln Gly Ile Gln Ala Leu Cys Leu
    1               5                  10                  15

 gcc ctg tgc att ttg atc cat acc ctg ctg agt cgg gac tca aaa gcc       96
 Ala Leu Cys Ile Leu Ile His Thr Leu Leu Ser Arg Asp Ser Lys Ala
              20                  25                  30

 aag gaa gtt gaa gac tta gaa ctc ttc atg ccg gaa gag gct gca ggc      144
 Lys Glu Val Glu Asp Leu Glu Leu Phe Met Pro Glu Glu Ala Ala Gly
          35                  40                  45

 aga ggc cgc acc cga tgg atg aat gaa cga acg aac gaa cga acg aac      192
 Arg Gly Arg Thr Arg Trp Met Asn Glu Arg Thr Asn Glu Arg Thr Asn
      50                  55                  60

 gaa cga acg aac gaa cga acg aac acc aaa gga cac agc aac cag tgc      240
 Glu Arg Thr Asn Glu Arg Thr Asn Thr Lys Gly His Ser Asn Gln Cys
  65                  70                  75                  80

 tag                                                                  243
 






      <210> 622
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 622
  atg gtg cca ctt ccg aag caa agc ctg aag ttc ttc tgt gct tta gaa      48
  Met Val Pro Leu Pro Lys Gln Ser Leu Lys Phe Phe Cys Ala Leu Glu
    1               5                  10                  15

 gtg gtg ttg cca tcc tgt gat tgc agg agt cct ggc att ggc ttg gtg       96
 Val Val Leu Pro Ser Cys Asp Cys Arg Ser Pro Gly Ile Gly Leu Val
              20                  25                  30

 gag gag cct atg gat aag gtg gag gaa gct tca tca cca aaa ggg gcc      144
 Glu Glu Pro Met Asp Lys Val Glu Glu Ala Ser Ser Pro Lys Gly Ala
          35                  40                  45

 att ccg tct gta cca acc ccc agt gac aag tgg gtc cag gac tat atc      192
 Ile Pro Ser Val Pro Thr Pro Ser Asp Lys Trp Val Gln Asp Tyr Ile
      50                  55                  60

 aag gac atg aag gag aac tga                                          213
 Lys Asp Met Lys Glu Asn 
  65                  70





      <210> 623
      <211> 342
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(342)

      <400> 623
  atg agt caa gta atg ttc cat gct atg tgt gta cca cag tgt tta acc      48
  Met Ser Gln Val Met Phe His Ala Met Cys Val Pro Gln Cys Leu Thr
    1               5                  10                  15

 att tac ctg ttg aag aac atc tgg att tca atc agt ata aaa ttg aca       96
 Ile Tyr Leu Leu Lys Asn Ile Trp Ile Ser Ile Ser Ile Lys Leu Thr
              20                  25                  30

 tgc atc tct aac aga gtg gac aaa ctt ttg ctt aaa ggg cca gat gcc      144
 Cys Ile Ser Asn Arg Val Asp Lys Leu Leu Leu Lys Gly Pro Asp Ala
          35                  40                  45

 tcg ggc gcc cgt gcc cca gcc agc cgc tca acc act cgc ctg gag cgg      192
 Ser Gly Ala Arg Ala Pro Ala Ser Arg Ser Thr Thr Arg Leu Glu Arg
      50                  55                  60

 ggg gcc tgc act tac cag acc gga cgc agc cat gtt ccg gcc ccg ctg      240
 Gly Ala Cys Thr Tyr Gln Thr Gly Arg Ser His Val Pro Ala Pro Leu
  65                  70                  75                  80

 agc cag cgc aac tgt ctg agg tgg aag ccc aca cgg acc aca gct cca      288
 Ser Gln Arg Asn Cys Leu Arg Trp Lys Pro Thr Arg Thr Thr Ala Pro
                  85                  90                  95

 gga agc cga gca aga aac gaa tcg ccg gaa tac cag gcc gcg gcc aag      336
 Gly Ser Arg Ala Arg Asn Glu Ser Pro Glu Tyr Gln Ala Ala Ala Lys
             100                 105                 110

 caa taa                                                              342
 Gln 






      <210> 624
      <211> 174
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(174)

      <400> 624
  atg ccc ttc cag gtg tgg aga gca gcc tgc gcg tca ctc gct gcc gcc      48
  Met Pro Phe Gln Val Trp Arg Ala Ala Cys Ala Ser Leu Ala Ala Ala
    1               5                  10                  15

 cca tcc tac ggg gca ctg gag cac aac tgt gtc gtc ctc cgc tac ctc       96
 Pro Ser Tyr Gly Ala Leu Glu His Asn Cys Val Val Leu Arg Tyr Leu
              20                  25                  30

 atg ggc ttc ctg cac acg ggc cct ccc act gtg acc ctg gcc tcg gcc      144
 Met Gly Phe Leu His Thr Gly Pro Pro Thr Val Thr Leu Ala Ser Ala
          35                  40                  45

 acc agg ctt gct ttg gcc aat ggg atg tga                              174
 Thr Arg Leu Ala Leu Ala Asn Gly Met 
      50                  55





      <210> 625
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 625
  atg atg cat ctg ctg ggc ttc tgc ggg ggc ctc agt aag cta aca atc      48
  Met Met His Leu Leu Gly Phe Cys Gly Gly Leu Ser Lys Leu Thr Ile
    1               5                  10                  15

 atg gca gaa ggt gaa ggg gga gcc agc act tca cat ggc tgg aag cag       96
 Met Ala Glu Gly Glu Gly Gly Ala Ser Thr Ser His Gly Trp Lys Gln
              20                  25                  30

 gaa gaa gag ttt aag acc gga tgt agt atg cct ttg gaa agc ctc agg      144
 Glu Glu Glu Phe Lys Thr Gly Cys Ser Met Pro Leu Glu Ser Leu Arg
          35                  40                  45

 acc cag agg tca gag ttc aca ttg gcc atg ttc atc cat acc aag ctg      192
 Thr Gln Arg Ser Glu Phe Thr Leu Ala Met Phe Ile His Thr Lys Leu
      50                  55                  60

 caa acc ctg gag cat gtg act gag gcc tta ttt agg gcc aaa ttc aag      240
 Gln Thr Leu Glu His Val Thr Glu Ala Leu Phe Arg Ala Lys Phe Lys
  65                  70                  75                  80

 ttc agt gaa tgc cca aaa agc cac atc tca aag aag tgc gat ttt act      288
 Phe Ser Glu Cys Pro Lys Ser His Ile Ser Lys Lys Cys Asp Phe Thr
                  85                  90                  95

 aag ttt aat gca tat aca ttt taa                                      312
 Lys Phe Asn Ala Tyr Thr Phe 
             100





      <210> 626
      <211> 1209
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1209)

      <400> 626
  atg gtg tgc gct cgg gcg gcc ctc ggt ccc ggc gcg ctc tgg gcc gcg      48
  Met Val Cys Ala Arg Ala Ala Leu Gly Pro Gly Ala Leu Trp Ala Ala
    1               5                  10                  15

 gcc tgg ggc gtc ctg ctg ctc aca gcc cct gcg ggg gcg cag cgt ggc       96
 Ala Trp Gly Val Leu Leu Leu Thr Ala Pro Ala Gly Ala Gln Arg Gly
              20                  25                  30

 cgg aag aag gtc gtg cac gtg ctg gag ggt gag tcg ggc tcg gta gtg      144
 Arg Lys Lys Val Val His Val Leu Glu Gly Glu Ser Gly Ser Val Val
          35                  40                  45

 gta cag aca gcg cct ggg cag gtg gta agc cac cgt ggt ggc acc atc      192
 Val Gln Thr Ala Pro Gly Gln Val Val Ser His Arg Gly Gly Thr Ile
      50                  55                  60

 gtc ttg ccc tgc cgc tac cac tat gag gca gcc gcc cac ggt cac gac      240
 Val Leu Pro Cys Arg Tyr His Tyr Glu Ala Ala Ala His Gly His Asp
  65                  70                  75                  80

 ggc gtc cgg ctc aag tgg aca aag gtg gtg gac ccg ctg gcc ttc acc      288
 Gly Val Arg Leu Lys Trp Thr Lys Val Val Asp Pro Leu Ala Phe Thr
                  85                  90                  95

 gac gtc ttc gtg gca cta ggc ccc cag cac cgg gca ttc ggc agc tac      336
 Asp Val Phe Val Ala Leu Gly Pro Gln His Arg Ala Phe Gly Ser Tyr
             100                 105                 110

 cgt ggg cgg gct gag ctg cag ggc gac ggg cct ggg gat gcc tcc ctg      384
 Arg Gly Arg Ala Glu Leu Gln Gly Asp Gly Pro Gly Asp Ala Ser Leu
         115                 120                 125

 gtc ctc cgc aac gtc acg ctg caa gac tac ggg cgc tat gag tgc gaa      432
 Val Leu Arg Asn Val Thr Leu Gln Asp Tyr Gly Arg Tyr Glu Cys Glu
     130                 135                 140

 gtc acc aat gag ctg gaa gat gac gct ggc atg gtc aag ctg gac ctg      480
 Val Thr Asn Glu Leu Glu Asp Asp Ala Gly Met Val Lys Leu Asp Leu
 145                 150                 155                 160

 gaa ggc gtg gtc ttt ccc tac cac ccc cgt gga ggc cga tac aag ctg      528
 Glu Gly Val Val Phe Pro Tyr His Pro Arg Gly Gly Arg Tyr Lys Leu
                 165                 170                 175

 acc ttc gcg gag gcg cag cgc gcg tgc gcc gag cag gac ggc atc ctg      576
 Thr Phe Ala Glu Ala Gln Arg Ala Cys Ala Glu Gln Asp Gly Ile Leu
             180                 185                 190

 gca tct gca gaa cag ctg cac gcg gcc tgg cgc gac ggc ctg gac tgg      624
 Ala Ser Ala Glu Gln Leu His Ala Ala Trp Arg Asp Gly Leu Asp Trp
         195                 200                 205

 tgc aac gcg ggc tgg ttg cgc gac ggc tca gtg caa tac ccc gtg aac      672
 Cys Asn Ala Gly Trp Leu Arg Asp Gly Ser Val Gln Tyr Pro Val Asn
     210                 215                 220

 cgg ccc cgg gag ccc tgc ggc ggc ctg ggg ggg acc ggg agt gca ggg      720
 Arg Pro Arg Glu Pro Cys Gly Gly Leu Gly Gly Thr Gly Ser Ala Gly
 225                 230                 235                 240

 ggc ggc ggt gat gcc aac ggg ggc ctg cgc aac tac ggg tat cgc cat      768
 Gly Gly Gly Asp Ala Asn Gly Gly Leu Arg Asn Tyr Gly Tyr Arg His
                 245                 250                 255

 aac gcc gag gaa cgc tac gac gcc ttc tgc ttc acg tcc aac ctg ccg      816
 Asn Ala Glu Glu Arg Tyr Asp Ala Phe Cys Phe Thr Ser Asn Leu Pro
             260                 265                 270

 ggg cgc gtg ttc ttc ctg aag ccg ctg cga cct gta ccc ttc tcc gga      864
 Gly Arg Val Phe Phe Leu Lys Pro Leu Arg Pro Val Pro Phe Ser Gly
         275                 280                 285

 gct gcg cgc gcg tgt gct gcg cgt ggc gcg gcc gtg gcc aag gtg ggg      912
 Ala Ala Arg Ala Cys Ala Ala Arg Gly Ala Ala Val Ala Lys Val Gly
     290                 295                 300

 cag ctg ttc gcc gcg tgg aag ctg cag ctg cta gac cgc tgc acc gcg      960
 Gln Leu Phe Ala Ala Trp Lys Leu Gln Leu Leu Asp Arg Cys Thr Ala
 305                 310                 315                 320

 ggt tgg ctg gcc gat ggc agt gcg cgc tac ccc atc gtg aac ccg cga     1008
 Gly Trp Leu Ala Asp Gly Ser Ala Arg Tyr Pro Ile Val Asn Pro Arg
                 325                 330                 335

 gcg cgc tgc gga ggc cgc agg cct ggt gtg cgc agc ctc ggc ttc ccg     1056
 Ala Arg Cys Gly Gly Arg Arg Pro Gly Val Arg Ser Leu Gly Phe Pro
             340                 345                 350

 gac gcc acc cga cgg ctc ttc ggc gtc tac tgc tac cgc gct cca gga     1104
 Asp Ala Thr Arg Arg Leu Phe Gly Val Tyr Cys Tyr Arg Ala Pro Gly
         355                 360                 365

 gca ccg gac ccg gca cct ggc ggc tgg ggc tgg ggc tgg gcg ggc ggc     1152
 Ala Pro Asp Pro Ala Pro Gly Gly Trp Gly Trp Gly Trp Ala Gly Gly
     370                 375                 380

 ggc ggc tgg gca ggg ggc gcg cgc gat cct gct gcc tgg acc cct ctg     1200
 Gly Gly Trp Ala Gly Gly Ala Arg Asp Pro Ala Ala Trp Thr Pro Leu
 385                 390                 395                 400

 cac gtc tag                                                         1209
 His Val 






      <210> 627
      <211> 771
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(771)

      <400> 627
  atg aga agc gga gct gcc cct gca cct gcg ctg gga gct gcc tgc ctc      48
  Met Arg Ser Gly Ala Ala Pro Ala Pro Ala Leu Gly Ala Ala Cys Leu
    1               5                  10                  15

 ctg ctt gtc ctg gcc atg ctg ggc ctt tct gtg ctg gaa ggt gca tct       96
 Leu Leu Val Leu Ala Met Leu Gly Leu Ser Val Leu Glu Gly Ala Ser
              20                  25                  30

 tgg gaa tct cag caa aag tcc aca tta tcc tct gtc ctg cat gtg gta      144
 Trp Glu Ser Gln Gln Lys Ser Thr Leu Ser Ser Val Leu His Val Val
          35                  40                  45

 gac cat tca ttt gtt aat ttg tcc atc ttt cca tct atc cac tta ctc      192
 Asp His Ser Phe Val Asn Leu Ser Ile Phe Pro Ser Ile His Leu Leu
      50                  55                  60

 atc tac cca ctc aac tac cca tct act tgc tca tcc atc cat cca tcc      240
 Ile Tyr Pro Leu Asn Tyr Pro Ser Thr Cys Ser Ser Ile His Pro Ser
  65                  70                  75                  80

 atc cat cct ccc atc cat cca tcc acc cac cag acc atc cat cca tcc      288
 Ile His Pro Pro Ile His Pro Ser Thr His Gln Thr Ile His Pro Ser
                  85                  90                  95

 atc cat tca ccc acc aaa cca tct atc cat cca tcc atc caa gta caa      336
 Ile His Ser Pro Thr Lys Pro Ser Ile His Pro Ser Ile Gln Val Gln
             100                 105                 110

 gac cat cca tcc atc cat cca tcc atc cac cca cca aac cat cca tcc      384
 Asp His Pro Ser Ile His Pro Ser Ile His Pro Pro Asn His Pro Ser
         115                 120                 125

 atc cat cca tcc atc cac cca ccc acc aga ccg tcc atc cat cca tct      432
 Ile His Pro Ser Ile His Pro Pro Thr Arg Pro Ser Ile His Pro Ser
     130                 135                 140

 atc cat cca tcc atc cat cca tcc atc cat cca tcc atc cac caa acc      480
 Ile His Pro Ser Ile His Pro Ser Ile His Pro Ser Ile His Gln Thr
 145                 150                 155                 160

 atc cat cca ccc acc aga acc atc tat cca tcc atc tat cca tcc atc      528
 Ile His Pro Pro Thr Arg Thr Ile Tyr Pro Ser Ile Tyr Pro Ser Ile
                 165                 170                 175

 cat cca tcc atc cat cca tcc atc cat cca tcc acc aaa cca tcc atc      576
 His Pro Ser Ile His Pro Ser Ile His Pro Ser Thr Lys Pro Ser Ile
             180                 185                 190

 cac cca ccc aac aga cca tcc atc cat cca tct atc cat cca tcc atc      624
 His Pro Pro Asn Arg Pro Ser Ile His Pro Ser Ile His Pro Ser Ile
         195                 200                 205

 cat cca tcc atc cat cca tcc atc cat cca cca aac cat cca tcc atc      672
 His Pro Ser Ile His Pro Ser Ile His Pro Pro Asn His Pro Ser Ile
     210                 215                 220

 cat cca tcc atc cat cca tcc atc cat cca ccc acc cat cca tcc atc      720
 His Pro Ser Ile His Pro Ser Ile His Pro Pro Thr His Pro Ser Ile
 225                 230                 235                 240

 aat ccg tct atc cat cca ttc atc tat caa tcc atc cat tca tcc atc      768
 Asn Pro Ser Ile His Pro Phe Ile Tyr Gln Ser Ile His Ser Ser Ile
                 245                 250                 255

 tag                                                                  771
 






      <210> 628
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 628
  atg gcc ggc ctg aac tgc ggg gtc tct atc gca ctg cta ggg gtt ctg      48
  Met Ala Gly Leu Asn Cys Gly Val Ser Ile Ala Leu Leu Gly Val Leu
    1               5                  10                  15

 ctg ctg ggt gcg gcg cgc ctg ccg cgc ggg gca gtc acc ctt gtg aat       96
 Leu Leu Gly Ala Ala Arg Leu Pro Arg Gly Ala Val Thr Leu Val Asn
              20                  25                  30

 gta tct tct acc atg act atc ctt gtt gat ata gta tct tct ata atg      144
 Val Ser Ser Thr Met Thr Ile Leu Val Asp Ile Val Ser Ser Ile Met
          35                  40                  45

 gcc ttc ctc att gac ata aca cct ttc aaa ggt tat ttt gga gag ctg      192
 Ala Phe Leu Ile Asp Ile Thr Pro Phe Lys Gly Tyr Phe Gly Glu Leu
      50                  55                  60

 tct gta atg gac atc ctc att gac ata ata cct cct gga agc tgc cct      240
 Ser Val Met Asp Ile Leu Ile Asp Ile Ile Pro Pro Gly Ser Cys Pro
  65                  70                  75                  80

 ggg ccc tct ggg gca gca aga aag gag cag gga gtg agt cag ctg gtg      288
 Gly Pro Ser Gly Ala Ala Arg Lys Glu Gln Gly Val Ser Gln Leu Val
                  85                  90                  95

 gtc atc ctt cag acc aca gtg aag cag agg atg gat tgc tgc caa agt      336
 Val Ile Leu Gln Thr Thr Val Lys Gln Arg Met Asp Cys Cys Gln Ser
             100                 105                 110

 atc gga agt aaa ggc agt gac gga ggt ggt gag gac atc gga gat gga      384
 Ile Gly Ser Lys Gly Ser Asp Gly Gly Gly Glu Asp Ile Gly Asp Gly
         115                 120                 125

 gga gga gca gat gct ctt cct gat tga                                  411
 Gly Gly Ala Asp Ala Leu Pro Asp 
     130                 135





      <210> 629
      <211> 1008
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1008)

      <400> 629
  atg gct aga gca ggc ttg agt tgg gtc ttt ctc ttc ccc cag gtg ctg      48
  Met Ala Arg Ala Gly Leu Ser Trp Val Phe Leu Phe Pro Gln Val Leu
    1               5                  10                  15

 ctc ctg cag gcc ata gtg acc gtg cct gag ctg cag ctc tcc acc agc       96
 Leu Leu Gln Ala Ile Val Thr Val Pro Glu Leu Gln Leu Ser Thr Ser
              20                  25                  30

 tgg gtg gac ttt agg acc tgc ttt gtg agc cag caa cga gtc tgg gag      144
 Trp Val Asp Phe Arg Thr Cys Phe Val Ser Gln Gln Arg Val Trp Glu
          35                  40                  45

 gtc tac cta atg cac ctg agc agc tgc cga agt tac tgg gcc aca gaa      192
 Val Tyr Leu Met His Leu Ser Ser Cys Arg Ser Tyr Trp Ala Thr Glu
      50                  55                  60

 act gga gag aag atg acg ccc cag gaa ggg agc agt aag cta tac aag      240
 Thr Gly Glu Lys Met Thr Pro Gln Glu Gly Ser Ser Lys Leu Tyr Lys
  65                  70                  75                  80

 gcc acg ttg gtg gtg caa gaa gtg ctt ggc aag aag ggc gtt ggc agc      288
 Ala Thr Leu Val Val Gln Glu Val Leu Gly Lys Lys Gly Val Gly Ser
                  85                  90                  95

 agc aca ctg ctc ctc tgg cca gca gtc ctg ggt gca cag acc agg caa      336
 Ser Thr Leu Leu Leu Trp Pro Ala Val Leu Gly Ala Gln Thr Arg Gln
             100                 105                 110

 gct ggt gtc aac gaa ggg cgg tca cag gta gct gac ttc ctt cgg atc      384
 Ala Gly Val Asn Glu Gly Arg Ser Gln Val Ala Asp Phe Leu Arg Ile
         115                 120                 125

 ccc gtc act ggg tgc cca gaa cag cgc agg aac ccg ccg agt cct ccg      432
 Pro Val Thr Gly Cys Pro Glu Gln Arg Arg Asn Pro Pro Ser Pro Pro
     130                 135                 140

 gcc cct ctg ggc acc ggg ggt cct gcc gag gag cgc ctg cag ttt cct      480
 Ala Pro Leu Gly Thr Gly Gly Pro Ala Glu Glu Arg Leu Gln Phe Pro
 145                 150                 155                 160

 ggg gta gct ggg tcc agg cgg ggt cga ggc cgc atc ttg cga gcg ggt      528
 Gly Val Ala Gly Ser Arg Arg Gly Arg Gly Arg Ile Leu Arg Ala Gly
                 165                 170                 175

 ggc att ggc agg gca tct ccg ggc gag ggc acc ggc gcc cca cgg ccg      576
 Gly Ile Gly Arg Ala Ser Pro Gly Glu Gly Thr Gly Ala Pro Arg Pro
             180                 185                 190

 cgc gca ggg cag ggg cgc ggg ggc ccc ggg aag ccc gag agc gga gga      624
 Arg Ala Gly Gln Gly Arg Gly Gly Pro Gly Lys Pro Glu Ser Gly Gly
         195                 200                 205

 ggc ggc ccc gtg gcc ctg cgg cca ggc gac tgt acc tgc tgc gtg ctg      672
 Gly Gly Pro Val Ala Leu Arg Pro Gly Asp Cys Thr Cys Cys Val Leu
     210                 215                 220

 aag tcc cag ccc agg cag cag cgg cga ggg gcg tgc tcc gcc atg gcc      720
 Lys Ser Gln Pro Arg Gln Gln Arg Arg Gly Ala Cys Ser Ala Met Ala
 225                 230                 235                 240

 ttt cgg gta agg ctg cgc gtc cgt cag tcc gtc cgt ccg cca cgc ggc      768
 Phe Arg Val Arg Leu Arg Val Arg Gln Ser Val Arg Pro Pro Arg Gly
                 245                 250                 255

 gtg ata gtc gcc gcg ctc cag cgc cca gag acg cag ggg ccc gcc cct      816
 Val Ile Val Ala Ala Leu Gln Arg Pro Glu Thr Gln Gly Pro Ala Pro
             260                 265                 270

 agc tcc gcc cgg ccg gac tgt gga ccg gag tca cga ggc ggg ctt gcg      864
 Ser Ser Ala Arg Pro Asp Cys Gly Pro Glu Ser Arg Gly Gly Leu Ala
         275                 280                 285

 ctc tgg cgc cgc ctg cgg ggc tac gcg agc cgg gac cgc gtc ctg tgc      912
 Leu Trp Arg Arg Leu Arg Gly Tyr Ala Ser Arg Asp Arg Val Leu Cys
     290                 295                 300

 aat cga cgg tgc ccc cac gca gcc cgc ttt cct tcg aag cgc acc ccc      960
 Asn Arg Arg Cys Pro His Ala Ala Arg Phe Pro Ser Lys Arg Thr Pro
 305                 310                 315                 320

 tct ggt tct ccc cat ctt cat ctt atg tct tca tgg gcc gtg ccc tga     1008
 Ser Gly Ser Pro His Leu His Leu Met Ser Ser Trp Ala Val Pro 
                 325                 330                 335





      <210> 630
      <211> 180
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(180)

      <400> 630
  atg gtg gcg gcc act ccc aag atg gca gca agc ctt ttg ttc tct gac      48
  Met Val Ala Ala Thr Pro Lys Met Ala Ala Ser Leu Leu Phe Ser Asp
    1               5                  10                  15

 ctg ggg ttc ttg gcc tca tgg att cca aag aat gga acc ctg ggc cat       96
 Leu Gly Phe Leu Ala Ser Trp Ile Pro Lys Asn Gly Thr Leu Gly His
              20                  25                  30

 gca gtg agt gtt ata gct cta tta gaa gcc gtg ggt cac gga aga gaa      144
 Ala Val Ser Val Ile Ala Leu Leu Glu Ala Val Gly His Gly Arg Glu
          35                  40                  45

 ccg tgg aac cca gcg act agt gtt cag ctc gat tag                      180
 Pro Trp Asn Pro Ala Thr Ser Val Gln Leu Asp 
      50                  55





      <210> 631
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 631
  atg gaa acg ttc tat ttt ggc att gtt ctt cga gca gcg tgc att ttg      48
  Met Glu Thr Phe Tyr Phe Gly Ile Val Leu Arg Ala Ala Cys Ile Leu
    1               5                  10                  15

 gta gac act agc ctt tca gtg ttt att cag atg gat aat caa ggc tac       96
 Val Asp Thr Ser Leu Ser Val Phe Ile Gln Met Asp Asn Gln Gly Tyr
              20                  25                  30

 tgt gga gcc gat atc aag gcc ctg tgc act gaa gcc gcc ctg att gca      144
 Cys Gly Ala Asp Ile Lys Ala Leu Cys Thr Glu Ala Ala Leu Ile Ala
          35                  40                  45

 ctg cgg agg cgt tat ccc cag atc tat gct agc agt cat aaa ctg cag      192
 Leu Arg Arg Arg Tyr Pro Gln Ile Tyr Ala Ser Ser His Lys Leu Gln
      50                  55                  60

 ctg gat gtt tcc tca ata gtg ctt agt gcc caa gat ttt tac cat gca      240
 Leu Asp Val Ser Ser Ile Val Leu Ser Ala Gln Asp Phe Tyr His Ala
  65                  70                  75                  80

 atg cag aat atc gtg cct gct tcc caa cgt gct gtg atg tct tca ggg      288
 Met Gln Asn Ile Val Pro Ala Ser Gln Arg Ala Val Met Ser Ser Gly
                  85                  90                  95

 cat gca cta tcc ccc atc ata aga cca ctg ctg gaa aga agc ttc aac      336
 His Ala Leu Ser Pro Ile Ile Arg Pro Leu Leu Glu Arg Ser Phe Asn
             100                 105                 110

 aac atc cta gca gtc ttg caa aaa gtg ttt cct cat gct gaa att agc      384
 Asn Ile Leu Ala Val Leu Gln Lys Val Phe Pro His Ala Glu Ile Ser
         115                 120                 125

 cag agt gac aaa aaa gaa ggt tgg aat gca gtg gcc tga                  423
 Gln Ser Asp Lys Lys Glu Gly Trp Asn Ala Val Ala 
     130                 135                 140





      <210> 632
      <211> 501
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(501)

      <400> 632
  atg ctg ttg ccg ctt ctc agt cta ctt ctt aat ttg aag cgg gtg gtg      48
  Met Leu Leu Pro Leu Leu Ser Leu Leu Leu Asn Leu Lys Arg Val Val
    1               5                  10                  15

 att gaa agt gaa gga ggt gga tat tgt tat gca agg aag aga tgt gaa       96
 Ile Glu Ser Glu Gly Gly Gly Tyr Cys Tyr Ala Arg Lys Arg Cys Glu
              20                  25                  30

 tat aca gga aat gag atc ctt aaa ggg gtt gcc gtc cag atg tta gat      144
 Tyr Thr Gly Asn Glu Ile Leu Lys Gly Val Ala Val Gln Met Leu Asp
          35                  40                  45

 caa aga gat tat gat tca ttc aac caa gtc gct gga ctt ttg aag gcc      192
 Gln Arg Asp Tyr Asp Ser Phe Asn Gln Val Ala Gly Leu Leu Lys Ala
      50                  55                  60

 tat cca agt cat ggt gcc ttt gag gtt gcg cct gtt act att caa aac      240
 Tyr Pro Ser His Gly Ala Phe Glu Val Ala Pro Val Thr Ile Gln Asn
  65                  70                  75                  80

 ttg gtc tca gga cgc ccc act cag cat gaa cac aga ctg cgt gct ggc      288
 Leu Val Ser Gly Arg Pro Thr Gln His Glu His Arg Leu Arg Ala Gly
                  85                  90                  95

 act ctt cct cct ttc cca gca aat gag cag gtt cca cag ctt ctg cca      336
 Thr Leu Pro Pro Phe Pro Ala Asn Glu Gln Val Pro Gln Leu Leu Pro
             100                 105                 110

 agg gat ctg ctc aca tca ggg gct gca ggc aac ccc ttc gat gct gaa      384
 Arg Asp Leu Leu Thr Ser Gly Ala Ala Gly Asn Pro Phe Asp Ala Glu
         115                 120                 125

 aat tct gga gac tcc cac agt ctc cag cct gca ggt cct tct gtc act      432
 Asn Ser Gly Asp Ser His Ser Leu Gln Pro Ala Gly Pro Ser Val Thr
     130                 135                 140

 gac aga aag aga ctc cac cca ctg ctc aga cac ctg tgc aga aat gaa      480
 Asp Arg Lys Arg Leu His Pro Leu Leu Arg His Leu Cys Arg Asn Glu
 145                 150                 155                 160

 ttc acg ggg tca ctt atg tga                                          501
 Phe Thr Gly Ser Leu Met 
                 165





      <210> 633
      <211> 402
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(402)

      <400> 633
  atg cct tgt agc cca cgt tcg ggc tcc cct ggc ttt gcc tct cct ttc      48
  Met Pro Cys Ser Pro Arg Ser Gly Ser Pro Gly Phe Ala Ser Pro Phe
    1               5                  10                  15

 ctg cat ctg gcc aca agc caa gtt ggg ttt cag ctg ctg ctc ctg ttt       96
 Leu His Leu Ala Thr Ser Gln Val Gly Phe Gln Leu Leu Leu Leu Phe
              20                  25                  30

 cta gga tgt ata ctc ccc tac cca ccc cct gct att atg atg gaa ttg      144
 Leu Gly Cys Ile Leu Pro Tyr Pro Pro Pro Ala Ile Met Met Glu Leu
          35                  40                  45

 gcg gtc tgc agt cag att ctt ccc gag gaa aat aat gaa cat gag agt      192
 Ala Val Cys Ser Gln Ile Leu Pro Glu Glu Asn Asn Glu His Glu Ser
      50                  55                  60

 cct caa gag agg gtg gag gga ggg gag aca gag aaa gac cca gac aga      240
 Pro Gln Glu Arg Val Glu Gly Gly Glu Thr Glu Lys Asp Pro Asp Arg
  65                  70                  75                  80

 cag aaa tgg aaa gac aaa aca gct aca gcg ctg aag gaa gta tct gtg      288
 Gln Lys Trp Lys Asp Lys Thr Ala Thr Ala Leu Lys Glu Val Ser Val
                  85                  90                  95

 cca cag aag aca ggc aga tcc tgt gac tgg cta gaa aga acg aac cag      336
 Pro Gln Lys Thr Gly Arg Ser Cys Asp Trp Leu Glu Arg Thr Asn Gln
             100                 105                 110

 atg tgg atc aac ata gag aaa aac tca tgg atg gta tct tgg att ctg      384
 Met Trp Ile Asn Ile Glu Lys Asn Ser Trp Met Val Ser Trp Ile Leu
         115                 120                 125

 gaa gag gat caa gtg tag                                              402
 Glu Glu Asp Gln Val 
     130





      <210> 634
      <211> 537
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(537)

      <400> 634
  atg ctc cgc cgc ctg ggc gcc caa gct gca gtc gcc ctc tgt gtg cag      48
  Met Leu Arg Arg Leu Gly Ala Gln Ala Ala Val Ala Leu Cys Val Gln
    1               5                  10                  15

 gca gca gct gcc tgg caa ccc ccg agc ccg ctc gcg ctc cca gca tcg       96
 Ala Ala Ala Ala Trp Gln Pro Pro Ser Pro Leu Ala Leu Pro Ala Ser
              20                  25                  30

 cag aac cag ggc cag gta tcc cag tgg ctg cga tca agc cag tca ttc      144
 Gln Asn Gln Gly Gln Val Ser Gln Trp Leu Arg Ser Ser Gln Ser Phe
          35                  40                  45

 tgc ccg gcg gcg gcg gct gca cag gag cca gaa ctg aga acc cgc cgc      192
 Cys Pro Ala Ala Ala Ala Ala Gln Glu Pro Glu Leu Arg Thr Arg Arg
      50                  55                  60

 tca gcc cca cac ggg gtg act gcc gag tgc ccg tgc cag cgg ccc aga      240
 Ser Ala Pro His Gly Val Thr Ala Glu Cys Pro Cys Gln Arg Pro Arg
  65                  70                  75                  80

 tct ccc tca ggt gga gga gtg ggc gag agg cac ggc ctg ggg gcc ctc      288
 Ser Pro Ser Gly Gly Gly Val Gly Glu Arg His Gly Leu Gly Ala Leu
                  85                  90                  95

 agg ctg ggc gcg ctg gcg atc cca agg ccg acc agg cca tgc acc tcc      336
 Arg Leu Gly Ala Leu Ala Ile Pro Arg Pro Thr Arg Pro Cys Thr Ser
             100                 105                 110

 agc ccg cct ggg cac cta agc tgc agc cgc ctt ctg tgt gca ggc agc      384
 Ser Pro Pro Gly His Leu Ser Cys Ser Arg Leu Leu Cys Ala Gly Ser
         115                 120                 125

 agc ctc cag gca act ccc gag ccc gcc cgc act ccc cac atc tcg gaa      432
 Ser Leu Gln Ala Thr Pro Glu Pro Ala Arg Thr Pro His Ile Ser Glu
     130                 135                 140

 cca ggg cca gat gtc cct gtg gct gcg gcg aag cca ggc ggt ctg ccc      480
 Pro Gly Pro Asp Val Pro Val Ala Ala Ala Lys Pro Gly Gly Leu Pro
 145                 150                 155                 160

 tgc agc agc tgc acg ggg gcg gga acc ggc cct cag ccc cat ccc cgg      528
 Cys Ser Ser Cys Thr Gly Ala Gly Thr Gly Pro Gln Pro His Pro Arg
                 165                 170                 175

 tgg ctg tag                                                          537
 Trp Leu 






      <210> 635
      <211> 513
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(513)

      <400> 635
  atg aag cca ttc tgg ctg gtc cta cct gtc agg agc gtt tca ttc cag      48
  Met Lys Pro Phe Trp Leu Val Leu Pro Val Arg Ser Val Ser Phe Gln
    1               5                  10                  15

 caa tgc cag ctg cag gaa cag ctg aat cca gct agc aat ttt tcc agt       96
 Gln Cys Gln Leu Gln Glu Gln Leu Asn Pro Ala Ser Asn Phe Ser Ser
              20                  25                  30

 gct ggc aga gcc agc ttc atc cta ctt cct tgg aca cca gcc cta gct      144
 Ala Gly Arg Ala Ser Phe Ile Leu Leu Pro Trp Thr Pro Ala Leu Ala
          35                  40                  45

 gcc aga gcc ctt tcc tca gag ctc agt gtt cag gcc cac aga ccc ctc      192
 Ala Arg Ala Leu Ser Ser Glu Leu Ser Val Gln Ala His Arg Pro Leu
      50                  55                  60

 ctc tca ggt ggg cac atc acg gaa act gtc ata ctt aat cgg agc ctg      240
 Leu Ser Gly Gly His Ile Thr Glu Thr Val Ile Leu Asn Arg Ser Leu
  65                  70                  75                  80

 gag aga gag att caa gca tct ccc tca cat ctg cat agc agg aag gag      288
 Glu Arg Glu Ile Gln Ala Ser Pro Ser His Leu His Ser Arg Lys Glu
                  85                  90                  95

 cag aga gaa atc gag aag att aag cag aga gct ttc ata ccc gag ata      336
 Gln Arg Glu Ile Glu Lys Ile Lys Gln Arg Ala Phe Ile Pro Glu Ile
             100                 105                 110

 acc cag ctg tgt gca aaa tca agc cta ttg aac gcg aaa gca ctg cac      384
 Thr Gln Leu Cys Ala Lys Ser Ser Leu Leu Asn Ala Lys Ala Leu His
         115                 120                 125

 cac caa aat aac tgc ttt aac cag gaa gga gaa gaa ccg atg ccc caa      432
 His Gln Asn Asn Cys Phe Asn Gln Glu Gly Glu Glu Pro Met Pro Gln
     130                 135                 140

 cag agc ccg gag agc cac aca gac aca agt tgc att tca aag tcg ctg      480
 Gln Ser Pro Glu Ser His Thr Asp Thr Ser Cys Ile Ser Lys Ser Leu
 145                 150                 155                 160

 ctg ttg tct cca ccc cac gtg tct ctg cct taa                          513
 Leu Leu Ser Pro Pro His Val Ser Leu Pro 
                 165                 170





      <210> 636
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 636
  atg ccc gac ctg ttt ttt cat gtt agt ttt atc ttg att ttg aag aca      48
  Met Pro Asp Leu Phe Phe His Val Ser Phe Ile Leu Ile Leu Lys Thr
    1               5                  10                  15

 gtt tcc ttc atg atc tac tta aat gaa gaa aga aca gca gag tgg atg       96
 Val Ser Phe Met Ile Tyr Leu Asn Glu Glu Arg Thr Ala Glu Trp Met
              20                  25                  30

 atc ctc atc ttt ccc tgc ttt tcg ttg gaa tgc atg att ggc tgg tgc      144
 Ile Leu Ile Phe Pro Cys Phe Ser Leu Glu Cys Met Ile Gly Trp Cys
          35                  40                  45

 aac tct gct tct tcc gat ctg taa                                      168
 Asn Ser Ala Ser Ser Asp Leu 
      50                  55





      <210> 637
      <211> 153
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(153)

      <400> 637
  atg gcc aac tgg aaa ggt ttt ccc ttc tgg cat caa ctg att ttc gca      48
  Met Ala Asn Trp Lys Gly Phe Pro Phe Trp His Gln Leu Ile Phe Ala
    1               5                  10                  15

 ggg ata gct gct tta aaa att gag ata aaa cgt gtg aag aaa tca gaa       96
 Gly Ile Ala Ala Leu Lys Ile Glu Ile Lys Arg Val Lys Lys Ser Glu
              20                  25                  30

 cag ttc atg gca cag aag cag tta cca gtg ttc ctg gac ttc act gga      144
 Gln Phe Met Ala Gln Lys Gln Leu Pro Val Phe Leu Asp Phe Thr Gly
          35                  40                  45

 cac ctc tga                                                          153
 His Leu 
      50





      <210> 638
      <211> 348
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(348)

      <400> 638
  atg gcc caa att ctt tac caa ata gca tta gtt aac caa tgt ttt cta      48
  Met Ala Gln Ile Leu Tyr Gln Ile Ala Leu Val Asn Gln Cys Phe Leu
    1               5                  10                  15

 aca ctg att ggc aaa gaa agt gca tca gaa tta cct ggg tcc ttt gtt       96
 Thr Leu Ile Gly Lys Glu Ser Ala Ser Glu Leu Pro Gly Ser Phe Val
              20                  25                  30

 aaa aag gca gat tcc tgg gcc cag cct cac ctg ctg aat gaa aat gtc      144
 Lys Lys Ala Asp Ser Trp Ala Gln Pro His Leu Leu Asn Glu Asn Val
          35                  40                  45

 tgg aga aac cag aag ttg tac ttg gcc aag gac gag cta acc cca aac      192
 Trp Arg Asn Gln Lys Leu Tyr Leu Ala Lys Asp Glu Leu Thr Pro Asn
      50                  55                  60

 agc aag agg ttt gag ttg gct cca aag cac aag cct cac aaa tat ccc      240
 Ser Lys Arg Phe Glu Leu Ala Pro Lys His Lys Pro His Lys Tyr Pro
  65                  70                  75                  80

 aat aaa gct ata aat ttg ggg ctc ttg agt ttt gct tgc aac cat aaa      288
 Asn Lys Ala Ile Asn Leu Gly Leu Leu Ser Phe Ala Cys Asn His Lys
                  85                  90                  95

 ctg gag cct aaa ttt gtt cca agc tca gtg atc aac atg cac aaa ctc      336
 Leu Glu Pro Lys Phe Val Pro Ser Ser Val Ile Asn Met His Lys Leu
             100                 105                 110

 ctt ggg gta tag                                                      348
 Leu Gly Val 
         115





      <210> 639
      <211> 489
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(489)

      <400> 639
  atg ggg acc aag cta cag tca tgg acg ttc tgg ctg tgc ctc ctg tgc      48
  Met Gly Thr Lys Leu Gln Ser Trp Thr Phe Trp Leu Cys Leu Leu Cys
    1               5                  10                  15

 aat gga atc agg agc acc ggc ctg ggc cgg cag ttg gac aat ggt gac       96
 Asn Gly Ile Arg Ser Thr Gly Leu Gly Arg Gln Leu Asp Asn Gly Asp
              20                  25                  30

 cgg atg agt ggc cag tca tgg ttc cac tca atg ctg gtg aat gaa cta      144
 Arg Met Ser Gly Gln Ser Trp Phe His Ser Met Leu Val Asn Glu Leu
          35                  40                  45

 tcc cct ggc agt ttg caa agc tca ggt cca cag ctg act gtg gaa ctg      192
 Ser Pro Gly Ser Leu Gln Ser Ser Gly Pro Gln Leu Thr Val Glu Leu
      50                  55                  60

 gaa gtg cca cag cac cca ccc ctg ccg cca agc cgt gcc cca ctt ctg      240
 Glu Val Pro Gln His Pro Pro Leu Pro Pro Ser Arg Ala Pro Leu Leu
  65                  70                  75                  80

 ctg cta aat gga gaa agg atg gag cct aca tta gaa acc aga gac ctg      288
 Leu Leu Asn Gly Glu Arg Met Glu Pro Thr Leu Glu Thr Arg Asp Leu
                  85                  90                  95

 gca aag tgg gtg gga cag gag gtt cct ggc aag cga cag aca gaa cta      336
 Ala Lys Trp Val Gly Gln Glu Val Pro Gly Lys Arg Gln Thr Glu Leu
             100                 105                 110

 cag aat gcc tgg ctg ctc ctc ttg aac ggc tgg ggc gag agg gat act      384
 Gln Asn Ala Trp Leu Leu Leu Leu Asn Gly Trp Gly Glu Arg Asp Thr
         115                 120                 125

 gca tgc gat gga act gat aaa cca gtt caa ata gca tta gac tca ctc      432
 Ala Cys Asp Gly Thr Asp Lys Pro Val Gln Ile Ala Leu Asp Ser Leu
     130                 135                 140

 acc gat act gtc tca ttg aaa cac att gct cat tta ttc ctc ttc gtc      480
 Thr Asp Thr Val Ser Leu Lys His Ile Ala His Leu Phe Leu Phe Val
 145                 150                 155                 160

 atc ctt tga                                                          489
 Ile Leu 






      <210> 640
      <211> 543
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(543)

      <400> 640
  atg cct tat cca cca tcc acc atc atg gtg ttc cac aca gca ttg cct      48
  Met Pro Tyr Pro Pro Ser Thr Ile Met Val Phe His Thr Ala Leu Pro
    1               5                  10                  15

 ctg acc acg gca ctc act tta cgg cta aag aag tgt ggc act gtg ctc       96
 Leu Thr Thr Ala Leu Thr Leu Arg Leu Lys Lys Cys Gly Thr Val Leu
              20                  25                  30

 ata ctc atg gaa ttc act ggt ctt acc atg ttc ccc atc atc ctg aag      144
 Ile Leu Met Glu Phe Thr Gly Leu Thr Met Phe Pro Ile Ile Leu Lys
          35                  40                  45

 cag gtg gaa tgc cct ttt gaa gtc aca ctt aca aca cca act ata gct      192
 Gln Val Glu Cys Pro Phe Glu Val Thr Leu Thr Thr Pro Thr Ile Ala
      50                  55                  60

 cta gaa acc aac aag tgt acc caa acc aca gcc acg tac ctc ttg ctt      240
 Leu Glu Thr Asn Lys Cys Thr Gln Thr Thr Ala Thr Tyr Leu Leu Leu
  65                  70                  75                  80

 gct gaa agg atc ctg aga gaa aag caa gac aaa gaa ata cag atc agc      288
 Ala Glu Arg Ile Leu Arg Glu Lys Gln Asp Lys Glu Ile Gln Ile Ser
                  85                  90                  95

 tcc gca agc cct aga aat agc aag gcc cag ctc aga aat cac aga gaa      336
 Ser Ala Ser Pro Arg Asn Ser Lys Ala Gln Leu Arg Asn His Arg Glu
             100                 105                 110

 ttg aga ttg act gca ctg aag gaa aaa gag aag gtg cag ttt cag atg      384
 Leu Arg Leu Thr Ala Leu Lys Glu Lys Glu Lys Val Gln Phe Gln Met
         115                 120                 125

 gtc tac aat aaa gct gtc cag tta gcc ctc aac aaa ggc ata acc tcc      432
 Val Tyr Asn Lys Ala Val Gln Leu Ala Leu Asn Lys Gly Ile Thr Ser
     130                 135                 140

 att tgc aaa gcg gag gat tcg ccc agt gct gag ccc gag aat ggg ctg      480
 Ile Cys Lys Ala Glu Asp Ser Pro Ser Ala Glu Pro Glu Asn Gly Leu
 145                 150                 155                 160

 tac cac agc ggc agc gaa ggg agg gga agg cga cgg aaa gga ggc ctg      528
 Tyr His Ser Gly Ser Glu Gly Arg Gly Arg Arg Arg Lys Gly Gly Leu
                 165                 170                 175

 cga aag gag cat taa                                                  543
 Arg Lys Glu His 
             180





      <210> 641
      <211> 1251
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1251)

      <400> 641
  atg gga aaa gtg cac tat ttg gtc aag agt gta ccg ttt ctc ttt ttg      48
  Met Gly Lys Val His Tyr Leu Val Lys Ser Val Pro Phe Leu Phe Leu
    1               5                  10                  15

 gtg gtg atg gat gtg ctg gtg atg gtt gat tgt tgt gat ggt ttt gta       96
 Val Val Met Asp Val Leu Val Met Val Asp Cys Cys Asp Gly Phe Val
              20                  25                  30

 ggc agt atc ccc tta gac ccc aag gcc caa caa gga ctc caa aag att      144
 Gly Ser Ile Pro Leu Asp Pro Lys Ala Gln Gln Gly Leu Gln Lys Ile
          35                  40                  45

 gtt aag gac cta aaa gcc caa ggc cta gta aaa ccg tgc aat agc ccc      192
 Val Lys Asp Leu Lys Ala Gln Gly Leu Val Lys Pro Cys Asn Ser Pro
      50                  55                  60

 tgc aat act cca att tta gga gta cag aaa ccc aac gga cag tgg agg      240
 Cys Asn Thr Pro Ile Leu Gly Val Gln Lys Pro Asn Gly Gln Trp Arg
  65                  70                  75                  80

 tta gtg caa gat ctc agg att atc aat gag gcc ctt gtc cct cta tac      288
 Leu Val Gln Asp Leu Arg Ile Ile Asn Glu Ala Leu Val Pro Leu Tyr
                  85                  90                  95

 cca gct gta cct aac cct tac act ctg ctt tct caa ata cca gag gaa      336
 Pro Ala Val Pro Asn Pro Tyr Thr Leu Leu Ser Gln Ile Pro Glu Glu
             100                 105                 110

 gca gag tgg ttt aca gtc ctg ggc ctt aag gat gac ttt ttc tgc atc      384
 Ala Glu Trp Phe Thr Val Leu Gly Leu Lys Asp Asp Phe Phe Cys Ile
         115                 120                 125

 cct gta cat cct gac tct caa ttc ttg ttt gcc ttt gaa gaa cct tca      432
 Pro Val His Pro Asp Ser Gln Phe Leu Phe Ala Phe Glu Glu Pro Ser
     130                 135                 140

 aac ccc aca tct caa ctc acc tgg act gtt tta ccg aaa ggg ttc agg      480
 Asn Pro Thr Ser Gln Leu Thr Trp Thr Val Leu Pro Lys Gly Phe Arg
 145                 150                 155                 160

 gat agc ccc cat cta ttt ggc cag gta tta gcc caa aac ttg agc caa      528
 Asp Ser Pro His Leu Phe Gly Gln Val Leu Ala Gln Asn Leu Ser Gln
                 165                 170                 175

 ttc tca tac ctg gac act ctt gtc ctt cgg tac gtg gat gat tta ctt      576
 Phe Ser Tyr Leu Asp Thr Leu Val Leu Arg Tyr Val Asp Asp Leu Leu
             180                 185                 190

 tta gct gcc cgt tca gaa acc ttg tgc cat caa gcc acc caa gca ctc      624
 Leu Ala Ala Arg Ser Glu Thr Leu Cys His Gln Ala Thr Gln Ala Leu
         195                 200                 205

 tta aat ttc ctc act acc tgt ggc tac aag gtt tcc aaa cca aag gct      672
 Leu Asn Phe Leu Thr Thr Cys Gly Tyr Lys Val Ser Lys Pro Lys Ala
     210                 215                 220

 cag ctc tgc tca cag gag gtt acg tac tta ggg cta aaa tta tcc aaa      720
 Gln Leu Cys Ser Gln Glu Val Thr Tyr Leu Gly Leu Lys Leu Ser Lys
 225                 230                 235                 240

 ggc acc agg gcc ctc ata aga tgg acc cct gaa gca gaa gca gct ttc      768
 Gly Thr Arg Ala Leu Ile Arg Trp Thr Pro Glu Ala Glu Ala Ala Phe
                 245                 250                 255

 cag gcc cta aag agg gcc cta acc caa gcc cca gtg tta agc ttg cca      816
 Gln Ala Leu Lys Arg Ala Leu Thr Gln Ala Pro Val Leu Ser Leu Pro
             260                 265                 270

 acg ggg caa gac ttt tct tta tat gtc aca gaa aaa aca gga ata gct      864
 Thr Gly Gln Asp Phe Ser Leu Tyr Val Thr Glu Lys Thr Gly Ile Ala
         275                 280                 285

 cta gga gtc ctt aca cag gtc caa ggg atg agc ttg caa ccc atg gca      912
 Leu Gly Val Leu Thr Gln Val Gln Gly Met Ser Leu Gln Pro Met Ala
     290                 295                 300

 tac ctg agt aag gaa att gat gta gcg gca aaa ggt tgg cct cat tgt      960
 Tyr Leu Ser Lys Glu Ile Asp Val Ala Ala Lys Gly Trp Pro His Cys
 305                 310                 315                 320

 tta cag gta gtg gtg gca gta gca gtc tta gta tct gaa gca gtt aaa     1008
 Leu Gln Val Val Val Ala Val Ala Val Leu Val Ser Glu Ala Val Lys
                 325                 330                 335

 ata ata caa gga aga gat ctt act gtg tgg aca tct cat gat gtg aaa     1056
 Ile Ile Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp Val Lys
             340                 345                 350

 ggc ata ctc act gct aaa gga gac ttg tgg ctg tca gac aac tgt tta     1104
 Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp Leu Ser Asp Asn Cys Leu
         355                 360                 365

 ctt aaa tat cag gct cta tta ctt gaa agg cca gtg ctg caa ctg cac     1152
 Leu Lys Tyr Gln Ala Leu Leu Leu Glu Arg Pro Val Leu Gln Leu His
     370                 375                 380

 act tgt gca act ctt aac cca gct aca ttt ctt cca gac aat gaa gaa     1200
 Thr Cys Ala Thr Leu Asn Pro Ala Thr Phe Leu Pro Asp Asn Glu Glu
 385                 390                 395                 400

 aag gta gaa tat aac tgt caa caa gta att gct caa acc tat gcc act     1248
 Lys Val Glu Tyr Asn Cys Gln Gln Val Ile Ala Gln Thr Tyr Ala Thr
                 405                 410                 415

 tga                                                                 1251
 






      <210> 642
      <211> 594
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(594)

      <400> 642
  atg aac gga aac atg cat ctg agg ttt tgg ttt tgc cag gca gcc ctt      48
  Met Asn Gly Asn Met His Leu Arg Phe Trp Phe Cys Gln Ala Ala Leu
    1               5                  10                  15

 ctc tac tac aga cat ttt caa ctg gaa gag cat act ctc tcc tat atg       96
 Leu Tyr Tyr Arg His Phe Gln Leu Glu Glu His Thr Leu Ser Tyr Met
              20                  25                  30

 gaa aaa ccc cag gct ctt atc gac cta atg cag tcc atc ttc tta act      144
 Glu Lys Pro Gln Ala Leu Ile Asp Leu Met Gln Ser Ile Phe Leu Thr
          35                  40                  45

 cac aac cca acc tgg gct gac tgc aaa cag ctc ctt ctg tca ctg ttc      192
 His Asn Pro Thr Trp Ala Asp Cys Lys Gln Leu Leu Leu Ser Leu Phe
      50                  55                  60

 aat aca gaa gaa cac cgc aga gta ata caa gcg gct cat cag agg cta      240
 Asn Thr Glu Glu His Arg Arg Val Ile Gln Ala Ala His Gln Arg Leu
  65                  70                  75                  80

 gaa aaa aat gcc cca gta ggt aca gga gat gtc aga cag tgt gct cgg      288
 Glu Lys Asn Ala Pro Val Gly Thr Gly Asp Val Arg Gln Cys Ala Arg
                  85                  90                  95

 cag gct ttg cca ata gaa act gac cca ggc tgg gac cca aat cag gcc      336
 Gln Ala Leu Pro Ile Glu Thr Asp Pro Gly Trp Asp Pro Asn Gln Ala
             100                 105                 110

 caa gat ctg ctg aag ttg ctg aga tac caa gag gct cta ata caa gga      384
 Gln Asp Leu Leu Lys Leu Leu Arg Tyr Gln Glu Ala Leu Ile Gln Gly
         115                 120                 125

 ata aag act gaa ggg aag aag gca aca aac act gga aag gtt tca gaa      432
 Ile Lys Thr Glu Gly Lys Lys Ala Thr Asn Thr Gly Lys Val Ser Glu
     130                 135                 140

 gtc tat cag aaa cca gat gaa agc ccc agt gag ttc tat ggg agg ctt      480
 Val Tyr Gln Lys Pro Asp Glu Ser Pro Ser Glu Phe Tyr Gly Arg Leu
 145                 150                 155                 160

 aga cag gct tac cgg cac tac aca cct ttt gac cca gaa gcg gca ggg      528
 Arg Gln Ala Tyr Arg His Tyr Thr Pro Phe Asp Pro Glu Ala Ala Gly
                 165                 170                 175

 aat cgg tgc atg gtt aat gcg gca ttt gtg agt cag gca caa aat gac      576
 Asn Arg Cys Met Val Asn Ala Ala Phe Val Ser Gln Ala Gln Asn Asp
             180                 185                 190

 att aag cga aag ttg tag                                              594
 Ile Lys Arg Lys Leu 
         195





      <210> 643
      <211> 984
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(984)

      <400> 643
  atg ggg tgg agg ggg ctg atc gca gcc ttg ccc ctg ctc tcc ttg gtg      48
  Met Gly Trp Arg Gly Leu Ile Ala Ala Leu Pro Leu Leu Ser Leu Val
    1               5                  10                  15

 cag cct gct ctg gga acc agc tca aag gat gag gat gta gga aga agc       96
 Gln Pro Ala Leu Gly Thr Ser Ser Lys Asp Glu Asp Val Gly Arg Ser
              20                  25                  30

 tgg tct gct gac tgt cat act tgt gac cag ctt gca cag gac atg gcc      144
 Trp Ser Ala Asp Cys His Thr Cys Asp Gln Leu Ala Gln Asp Met Ala
          35                  40                  45

 gag gag gca gcc cag aac att tct gat gac cag gaa agg tgt ctc cag      192
 Glu Glu Ala Ala Gln Asn Ile Ser Asp Asp Gln Glu Arg Cys Leu Gln
      50                  55                  60

 gct gcc tgc tgc ctt tcc ttt ggt ggt gag ctg tct gtg agc act gac      240
 Ala Ala Cys Cys Leu Ser Phe Gly Gly Glu Leu Ser Val Ser Thr Asp
  65                  70                  75                  80

 aag agc tgg ggt ctt cat ctg tgc agc tgt agc cct cct gga ggt gga      288
 Lys Ser Trp Gly Leu His Leu Cys Ser Cys Ser Pro Pro Gly Gly Gly
                  85                  90                  95

 ttg tgg gtc gag gtc tat gct aat cat gtg ctt ctt atg agt gat ggg      336
 Leu Trp Val Glu Val Tyr Ala Asn His Val Leu Leu Met Ser Asp Gly
             100                 105                 110

 aag tgt ggc tgt cct tgg tgt gct ctg aat gga aag gca gaa gac cgg      384
 Lys Cys Gly Cys Pro Trp Cys Ala Leu Asn Gly Lys Ala Glu Asp Arg
         115                 120                 125

 gaa tca cag agc cca tcc tca tca gct tcc agg cag aag aac att tgg      432
 Glu Ser Gln Ser Pro Ser Ser Ser Ala Ser Arg Gln Lys Asn Ile Trp
     130                 135                 140

 aaa aca act agt gaa gca gcg tta agt gtt gtt aat gaa aaa aca cag      480
 Lys Thr Thr Ser Glu Ala Ala Leu Ser Val Val Asn Glu Lys Thr Gln
 145                 150                 155                 160

 gct gtt gtt aat gaa aaa aca cag gcg cct ctg gat tgt gat aac agt      528
 Ala Val Val Asn Glu Lys Thr Gln Ala Pro Leu Asp Cys Asp Asn Ser
                 165                 170                 175

 gct gat agt ctc cga gtc ttt gct gac agc agt att ggg gag aat tgg      576
 Ala Asp Ser Leu Arg Val Phe Ala Asp Ser Ser Ile Gly Glu Asn Trp
             180                 185                 190

 acc ctt cag atg gtt tgt gac cca gac act tgg atg cgt ggg ccc agc      624
 Thr Leu Gln Met Val Cys Asp Pro Asp Thr Trp Met Arg Gly Pro Ser
         195                 200                 205

 tcc cac ggc ctt ccg cct ggc att cct cgc acc ccc agc ttc acg gca      672
 Ser His Gly Leu Pro Pro Gly Ile Pro Arg Thr Pro Ser Phe Thr Ala
     210                 215                 220

 tcg cag tct ggt tct gag atc ctc tat ccc cct act cag cat cct cct      720
 Ser Gln Ser Gly Ser Glu Ile Leu Tyr Pro Pro Thr Gln His Pro Pro
 225                 230                 235                 240

 gtg gcc atc cta gct cga aat tct gat aac ttc atg aac cct gtt ctt      768
 Val Ala Ile Leu Ala Arg Asn Ser Asp Asn Phe Met Asn Pro Val Leu
                 245                 250                 255

 aat tgc tcc ctg gaa gtg gaa gct cgg gca cct cca aat ctg gga ttc      816
 Asn Cys Ser Leu Glu Val Glu Ala Arg Ala Pro Pro Asn Leu Gly Phe
             260                 265                 270

 cgt gtt cat atg gct tct gga gag gct ctc tgt ctg atg atg gat ttc      864
 Arg Val His Met Ala Ser Gly Glu Ala Leu Cys Leu Met Met Asp Phe
         275                 280                 285

 ggg gac agt tct ggg gtt gaa atg agg cta cac aac atg tct gag gca      912
 Gly Asp Ser Ser Gly Val Glu Met Arg Leu His Asn Met Ser Glu Ala
     290                 295                 300

 atg gcg gtg act gcc tac cac cag tac tca aaa ggt gat ttg ctg gct      960
 Met Ala Val Thr Ala Tyr His Gln Tyr Ser Lys Gly Asp Leu Leu Ala
 305                 310                 315                 320

 tcc ctt gtc act cat ctt ctc tag                                      984
 Ser Leu Val Thr His Leu Leu 
                 325





      <210> 644
      <211> 123
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(123)

      <400> 644
  atg gcc atc act ctc tgc tct att cca act ctg gca gca gat agc tgc      48
  Met Ala Ile Thr Leu Cys Ser Ile Pro Thr Leu Ala Ala Asp Ser Cys
    1               5                  10                  15

 caa gct gtt agc aat cct gtg gat gaa gcc aca tgg caa gca agc gat       96
 Gln Ala Val Ser Asn Pro Val Asp Glu Ala Thr Trp Gln Ala Ser Asp
              20                  25                  30

 tgt tgc tta ccc agc aac agc cag tga                                  123
 Cys Cys Leu Pro Ser Asn Ser Gln 
          35                  40





      <210> 645
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 645
  atg tgg ctc ctg atc atc tgt tgt aaa tct gcc agc gca ttg gta ata      48
  Met Trp Leu Leu Ile Ile Cys Cys Lys Ser Ala Ser Ala Leu Val Ile
    1               5                  10                  15

 tgt tgg ata aag aaa ttc cac cca gta ttt gaa gag tca ctt ctt tac       96
 Cys Trp Ile Lys Lys Phe His Pro Val Phe Glu Glu Ser Leu Leu Tyr
              20                  25                  30

 tta ctg cag gaa ggc agt ctt tgc tac tta cag cga aag aaa aca gac      144
 Leu Leu Gln Glu Gly Ser Leu Cys Tyr Leu Gln Arg Lys Lys Thr Asp
          35                  40                  45

 ttt att ttc tta gtg cat ttg ctg gta ggt caa gga ggg atg gaa ttt      192
 Phe Ile Phe Leu Val His Leu Leu Val Gly Gln Gly Gly Met Glu Phe
      50                  55                  60

 gaa tta gtg ttc aga ttc aca gat cct acc tat gtg ttc ttc agt aga      240
 Glu Leu Val Phe Arg Phe Thr Asp Pro Thr Tyr Val Phe Phe Ser Arg
  65                  70                  75                  80

 gga ttt tct gtg atc cta aaa caa acg gaa agc tat ata att tat cag      288
 Gly Phe Ser Val Ile Leu Lys Gln Thr Glu Ser Tyr Ile Ile Tyr Gln
                  85                  90                  95

 tac ttc cga aag aga gag act aaa gtc atg gca gtg ttg gcc aaa tta      336
 Tyr Phe Arg Lys Arg Glu Thr Lys Val Met Ala Val Leu Ala Lys Leu
             100                 105                 110

 att tta aaa ctg aac aag tca tga                                      360
 Ile Leu Lys Leu Asn Lys Ser 
         115





      <210> 646
      <211> 276
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(276)

      <400> 646
  atg atg agt act ttg act gtc ctg aag cac atg ctc act cct gca tta      48
  Met Met Ser Thr Leu Thr Val Leu Lys His Met Leu Thr Pro Ala Leu
    1               5                  10                  15

 gca agc agg ctt cag cga tta gcc aaa gat ctt cta aaa caa gta caa       96
 Ala Ser Arg Leu Gln Arg Leu Ala Lys Asp Leu Leu Lys Gln Val Gln
              20                  25                  30

 gtt caa gac agt ggc tca tgg gca aac aat aaa gtg tct gct ttg gat      144
 Val Gln Asp Ser Gly Ser Trp Ala Asn Asn Lys Val Ser Ala Leu Asp
          35                  40                  45

 cgg acc cta gga gag atc act aga ata ctg gaa aaa gag ata gtg ctc      192
 Arg Thr Leu Gly Glu Ile Thr Arg Ile Leu Glu Lys Glu Ile Val Leu
      50                  55                  60

 aac tac att ttg gca tca gac agt aca gtc gtc tgg agg aat cga aag      240
 Asn Tyr Ile Leu Ala Ser Asp Ser Thr Val Val Trp Arg Asn Arg Lys
  65                  70                  75                  80

 cag cct att cag tgt ggc att gtg gca gag ctg taa                      276
 Gln Pro Ile Gln Cys Gly Ile Val Ala Glu Leu 
                  85                  90





      <210> 647
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 647
  atg ctc aat ttc gct ggc cca gtg acg caa caa ttt gtc tcc ttt ttt      48
  Met Leu Asn Phe Ala Gly Pro Val Thr Gln Gln Phe Val Ser Phe Phe
    1               5                  10                  15

 gta ctc ctt gca gtt aac acc ttc atg cca agg aga gtg gca ctt aaa       96
 Val Leu Leu Ala Val Asn Thr Phe Met Pro Arg Arg Val Ala Leu Lys
              20                  25                  30

 aca cca gat gaa ttg gca gat gtc ttc cct att tct tgc aac cag att      144
 Thr Pro Asp Glu Leu Ala Asp Val Phe Pro Ile Ser Cys Asn Gln Ile
          35                  40                  45

 cag tac ctt tct tat gga act tcc att ggg gat gta gat gtc taa          189
 Gln Tyr Leu Ser Tyr Gly Thr Ser Ile Gly Asp Val Asp Val 
      50                  55                  60





      <210> 648
      <211> 1296
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1296)

      <400> 648
  atg ggg ttc aca gtc ctg ctg gcc agc acc ttt ctc tgc ctc ttt ctg      48
  Met Gly Phe Thr Val Leu Leu Ala Ser Thr Phe Leu Cys Leu Phe Leu
    1               5                  10                  15

 gct ccc ctg gtt tgt cgt ttt ctg gtg tct att cct aaa ttc tcc tca       96
 Ala Pro Leu Val Cys Arg Phe Leu Val Ser Ile Pro Lys Phe Ser Ser
              20                  25                  30

 ttc tgc tcc ttc aca ttt aaa tcg acc ccc aga cag gat cag gac ctc      144
 Phe Cys Ser Phe Thr Phe Lys Ser Thr Pro Arg Gln Asp Gln Asp Leu
          35                  40                  45

 ctg gcc ttc ttg gag atg tgg gct cta tgc agg gat gac aga agc caa      192
 Leu Ala Phe Leu Glu Met Trp Ala Leu Cys Arg Asp Asp Arg Ser Gln
      50                  55                  60

 tgt ctg gag ccc tcc ccc aac act gca gag ctg gag cct gct cag agc      240
 Cys Leu Glu Pro Ser Pro Asn Thr Ala Glu Leu Glu Pro Ala Gln Ser
  65                  70                  75                  80

 tca caa gtc atc aag gaa aat ccc ctg ggc cct cag aga tat gac cac      288
 Ser Gln Val Ile Lys Glu Asn Pro Leu Gly Pro Gln Arg Tyr Asp His
                  85                  90                  95

 tgg acc tac agg gtg gcc agt gca ggc aca aag atc tgc cac tcg ctg      336
 Trp Thr Tyr Arg Val Ala Ser Ala Gly Thr Lys Ile Cys His Ser Leu
             100                 105                 110

 ctt aaa ccc cca ccc atg ggg agc ccc cca ttc act gtg gga agt cat      384
 Leu Lys Pro Pro Pro Met Gly Ser Pro Pro Phe Thr Val Gly Ser His
         115                 120                 125

 agg aac tgc cat gcc agt gag cca gac ccg gcc cag gcc ctg cgg tca      432
 Arg Asn Cys His Ala Ser Glu Pro Asp Pro Ala Gln Ala Leu Arg Ser
     130                 135                 140

 gtc acc tgc cac ctg ggt gat ggt gtg cct gtg atc ctc ttc acg ctc      480
 Val Thr Cys His Leu Gly Asp Gly Val Pro Val Ile Leu Phe Thr Leu
 145                 150                 155                 160

 ttc cca gcc gac tct ccc tct ctg cga gcc cat gtt cct ggc cac ggt      528
 Phe Pro Ala Asp Ser Pro Ser Leu Arg Ala His Val Pro Gly His Gly
                 165                 170                 175

 ccc tca gcc gcc ctg gaa gcc gcc ggc acc agc cgg tgt tct gct tca      576
 Pro Ser Ala Ala Leu Glu Ala Ala Gly Thr Ser Arg Cys Ser Ala Ser
             180                 185                 190

 aag cgg gcg cgc ggt gac cgg act gac aag gag ggg ctt cat gcg aaa      624
 Lys Arg Ala Arg Gly Asp Arg Thr Asp Lys Glu Gly Leu His Ala Lys
         195                 200                 205

 gtc ccc ctc ccc tcc cag gca ccg cgg gtc ccc ctg cgc agt cct tct      672
 Val Pro Leu Pro Ser Gln Ala Pro Arg Val Pro Leu Arg Ser Pro Ser
     210                 215                 220

 ctg tac ctt atc tcc atg aac ggc atc gtt atc cat gcc gca ttg gac      720
 Leu Tyr Leu Ile Ser Met Asn Gly Ile Val Ile His Ala Ala Leu Asp
 225                 230                 235                 240

 tct gcc ctt gtc cac aag gag agc aca cag gag aga atg gct gct gtg      768
 Ser Ala Leu Val His Lys Glu Ser Thr Gln Glu Arg Met Ala Ala Val
                 245                 250                 255

 tct ccg acc acc aga tgc cag gaa tca gtg aca ttc gaa gac gtt gcc      816
 Ser Pro Thr Thr Arg Cys Gln Glu Ser Val Thr Phe Glu Asp Val Ala
             260                 265                 270

 gtg gtt ttc aca gat gaa gag tgg agt cgt ctg gtc ccc ata cag agg      864
 Val Val Phe Thr Asp Glu Glu Trp Ser Arg Leu Val Pro Ile Gln Arg
         275                 280                 285

 gac ctc tac aag gag gtg atg ctg gag aac tat aac agc att gtg tca      912
 Asp Leu Tyr Lys Glu Val Met Leu Glu Asn Tyr Asn Ser Ile Val Ser
     290                 295                 300

 ttg gcg cca ccc cca ccc agt aag aat cag ctc agc ctc atc cac atg      960
 Leu Ala Pro Pro Pro Pro Ser Lys Asn Gln Leu Ser Leu Ile His Met
 305                 310                 315                 320

 ttc ccc act tgg atg agg act ggg ctc gaa gca ctc cag gcc tat gtg     1008
 Phe Pro Thr Trp Met Arg Thr Gly Leu Glu Ala Leu Gln Ala Tyr Val
                 325                 330                 335

 gag att cct ttg cag cca aaa gtc tcc aag ggg act ccc gtt ctc aga     1056
 Glu Ile Pro Leu Gln Pro Lys Val Ser Lys Gly Thr Pro Val Leu Arg
             340                 345                 350

 gga gct gtc ctc cga agt cac tgt ggg acg ctg cag caa gtg att ctg     1104
 Gly Ala Val Leu Arg Ser His Cys Gly Thr Leu Gln Gln Val Ile Leu
         355                 360                 365

 cct ctt ggc ccc agc ttc ctc tct gca aat ggc aac tca cag cag tct     1152
 Pro Leu Gly Pro Ser Phe Leu Ser Ala Asn Gly Asn Ser Gln Gln Ser
     370                 375                 380

 ccc cac act ggg ggc tgg tgt gaa ctg gct aaa act aca gat gtg agt     1200
 Pro His Thr Gly Gly Trp Cys Glu Leu Ala Lys Thr Thr Asp Val Ser
 385                 390                 395                 400

 atg aag ctt ctg gca ctg agc cca gca cta cca ata cct ggg aat aag     1248
 Met Lys Leu Leu Ala Leu Ser Pro Ala Leu Pro Ile Pro Gly Asn Lys
                 405                 410                 415

 ttg tcg ttc atg cag gag gct gac agc tca gtg gaa aca gat gca taa     1296
 Leu Ser Phe Met Gln Glu Ala Asp Ser Ser Val Glu Thr Asp Ala 
             420                 425                 430





      <210> 649
      <211> 261
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(261)

      <400> 649
  atg ttc cgt ctc atc ctt ttg cct gtg ctt aag ctg caa gga gat att      48
  Met Phe Arg Leu Ile Leu Leu Pro Val Leu Lys Leu Gln Gly Asp Ile
    1               5                  10                  15

 gat caa caa gag atg att cca agt aag aag aat gct gtt ctt gtg gat       96
 Asp Gln Gln Glu Met Ile Pro Ser Lys Lys Asn Ala Val Leu Val Asp
              20                  25                  30

 ggg gtt gtg ctg aat ggt cct aca aca gat gca aaa gct gga gaa aaa      144
 Gly Val Val Leu Asn Gly Pro Thr Thr Asp Ala Lys Ala Gly Glu Lys
          35                  40                  45

 ttt gtt gaa gag gcc tgt agg cta ata atg gaa gag gtg gtt ttg aaa      192
 Phe Val Glu Glu Ala Cys Arg Leu Ile Met Glu Glu Val Val Leu Lys
      50                  55                  60

 gct aca gat gtc aat gag aag ccc ctg aaa cca ctg att ttc ttt ccc      240
 Ala Thr Asp Val Asn Glu Lys Pro Leu Lys Pro Leu Ile Phe Phe Pro
  65                  70                  75                  80

 tat gat act tgc ctt ttc tag                                          261
 Tyr Asp Thr Cys Leu Phe 
                  85





      <210> 650
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 650
  atg gct gtg gct cta agt ata atc ctg cct ctt gga gca ggc tgc aaa      48
  Met Ala Val Ala Leu Ser Ile Ile Leu Pro Leu Gly Ala Gly Cys Lys
    1               5                  10                  15

 gca gca gag gga cgc tca tac agc acg ttg ggg cct tct aat gaa ccc       96
 Ala Ala Glu Gly Arg Ser Tyr Ser Thr Leu Gly Pro Ser Asn Glu Pro
              20                  25                  30

 cat tac tcg gaa ggc agc att tcc atg cag agt gag tcg cca gca ggc      144
 His Tyr Ser Glu Gly Ser Ile Ser Met Gln Ser Glu Ser Pro Ala Gly
          35                  40                  45

 act tgg ctt tgc agg gct cca ggt gac ctg ttt gca ttt aca tcc aag      192
 Thr Trp Leu Cys Arg Ala Pro Gly Asp Leu Phe Ala Phe Thr Ser Lys
      50                  55                  60

 gtc cca aaa aca gag gcc aaa atg cag gag gca aca gga cca ttc gca      240
 Val Pro Lys Thr Glu Ala Lys Met Gln Glu Ala Thr Gly Pro Phe Ala
  65                  70                  75                  80

 cag ttg cag gtg tac aat ctt cct gtg ctg ctg aac agc tgg aat tct      288
 Gln Leu Gln Val Tyr Asn Leu Pro Val Leu Leu Asn Ser Trp Asn Ser
                  85                  90                  95

 gac atg ggg cac ttc cag aca tca cca gac atc act gaa ccc caa tat      336
 Asp Met Gly His Phe Gln Thr Ser Pro Asp Ile Thr Glu Pro Gln Tyr
             100                 105                 110

 ctg ctt gac gtg atc tga                                              354
 Leu Leu Asp Val Ile 
         115





      <210> 651
      <211> 465
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(465)

      <400> 651
  atg cgg atc ccg ccc tcc cgg ccc gcg cgg ggc ctg tgg acg cgg tgg      48
  Met Arg Ile Pro Pro Ser Arg Pro Ala Arg Gly Leu Trp Thr Arg Trp
    1               5                  10                  15

 gtc ccg gtg acc gtg ctc ccc ggc tgc gtg ggc tgc agg acc gtc gcg       96
 Val Pro Val Thr Val Leu Pro Gly Cys Val Gly Cys Arg Thr Val Ala
              20                  25                  30

 gcg ctg gcg tcc tgg acc gtg cgc gat gtg aag gaa cgt atc ttc gcg      144
 Ala Leu Ala Ser Trp Thr Val Arg Asp Val Lys Glu Arg Ile Phe Ala
          35                  40                  45

 gag act ggc ttc ccg gtg tcg gag cag cgg ctg tgg cgc ggc ggc cgc      192
 Glu Thr Gly Phe Pro Val Ser Glu Gln Arg Leu Trp Arg Gly Gly Arg
      50                  55                  60

 gag tta tct gac tgg atc aag att gga gat ctg act tcc aaa aat tgt      240
 Glu Leu Ser Asp Trp Ile Lys Ile Gly Asp Leu Thr Ser Lys Asn Cys
  65                  70                  75                  80

 cat ctt ttt gta aac ctt caa tca aaa ggc tta aaa ggg gga ggt cga      288
 His Leu Phe Val Asn Leu Gln Ser Lys Gly Leu Lys Gly Gly Gly Arg
                  85                  90                  95

 ttt ggt cag aca acg cca cca ctt gtt gat ttt ctc aag gac att ttg      336
 Phe Gly Gln Thr Thr Pro Pro Leu Val Asp Phe Leu Lys Asp Ile Leu
             100                 105                 110

 aga aga tat cca gaa gga gga cag att ctt aag atc att gtg cag ggc      384
 Arg Arg Tyr Pro Glu Gly Gly Gln Ile Leu Lys Ile Ile Val Gln Gly
         115                 120                 125

 ttt aca cgt caa cca acc aac caa cca acc aac caa cca gcc agc cag      432
 Phe Thr Arg Gln Pro Thr Asn Gln Pro Thr Asn Gln Pro Ala Ser Gln
     130                 135                 140

 cca acc ggc cag cca aat aca ttc tac gat tag                          465
 Pro Thr Gly Gln Pro Asn Thr Phe Tyr Asp 
 145                 150





      <210> 652
      <211> 873
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(873)

      <400> 652
  atg gtc atg ctg caa att ccc gtg gcc agc acc cga ggc ctg ctg gct      48
  Met Val Met Leu Gln Ile Pro Val Ala Ser Thr Arg Gly Leu Leu Ala
    1               5                  10                  15

 ccg atc tgg gcc acg tgt aca acc agg aga gtg ggg ctg cac aca gca       96
 Pro Ile Trp Ala Thr Cys Thr Thr Arg Arg Val Gly Leu His Thr Ala
              20                  25                  30

 gca ggc cca gga gga aat cgt gct ttg ata gcc cca ggc atc gta ttt      144
 Ala Gly Pro Gly Gly Asn Arg Ala Leu Ile Ala Pro Gly Ile Val Phe
          35                  40                  45

 cat cgt att tca caa act cca aat ctg cag gtg ctg gag act ttg aag      192
 His Arg Ile Ser Gln Thr Pro Asn Leu Gln Val Leu Glu Thr Leu Lys
      50                  55                  60

 gag tct ccg ttt ccc ttg gta gaa aca aga ggt agg aac aag cag gtg      240
 Glu Ser Pro Phe Pro Leu Val Glu Thr Arg Gly Arg Asn Lys Gln Val
  65                  70                  75                  80

 gaa agc cag ggt tac tcc ttc cag cca atg ggt ctg ggg ctg cag cac      288
 Glu Ser Gln Gly Tyr Ser Phe Gln Pro Met Gly Leu Gly Leu Gln His
                  85                  90                  95

 aca aag ttg aca tcc cga aag gcc att ttc ctc gat cgc ttc aga cct      336
 Thr Lys Leu Thr Ser Arg Lys Ala Ile Phe Leu Asp Arg Phe Arg Pro
             100                 105                 110

 ggc att ggg tgg aca gac cac atg att cag cat cca aat tgg aga tct      384
 Gly Ile Gly Trp Thr Asp His Met Ile Gln His Pro Asn Trp Arg Ser
         115                 120                 125

 ctc aat aac aga aag aga gaa aaa att ttt tct aat ggc caa ctc aac      432
 Leu Asn Asn Arg Lys Arg Glu Lys Ile Phe Ser Asn Gly Gln Leu Asn
     130                 135                 140

 tcc ctc aaa cca cag ttt aag ccc atc cta tct gcc tgg ttc ttc aat      480
 Ser Leu Lys Pro Gln Phe Lys Pro Ile Leu Ser Ala Trp Phe Phe Asn
 145                 150                 155                 160

 gac aac aat tca tct cag ggt cat gga caa aaa cga agc cct tgt tca      528
 Asp Asn Asn Ser Ser Gln Gly His Gly Gln Lys Arg Ser Pro Cys Ser
                 165                 170                 175

 gag gaa gca cag ctt ttt cag agg ctg aaa cct tgg ata ttt ttt tct      576
 Glu Glu Ala Gln Leu Phe Gln Arg Leu Lys Pro Trp Ile Phe Phe Ser
             180                 185                 190

 ggg cca gtc tcc tca aga gca tcc tgc agt gct aca gtc agg aaa ttt      624
 Gly Pro Val Ser Ser Arg Ala Ser Cys Ser Ala Thr Val Arg Lys Phe
         195                 200                 205

 cat gtt tat gtc ttt gga ctc cac gct ggt gat ttc aga ccc aca gca      672
 His Val Tyr Val Phe Gly Leu His Ala Gly Asp Phe Arg Pro Thr Ala
     210                 215                 220

 gta gca atg gca gca ttc ccg gag gga aag gaa ccc aaa ggt atc act      720
 Val Ala Met Ala Ala Phe Pro Glu Gly Lys Glu Pro Lys Gly Ile Thr
 225                 230                 235                 240

 gat acc ctg ccg gac aga ggg gct ttt atg gct gct acc att act gcc      768
 Asp Thr Leu Pro Asp Arg Gly Ala Phe Met Ala Ala Thr Ile Thr Ala
                 245                 250                 255

 act tcc tca gaa cca agt ccc aga atc aga gga gta gca gtg gat tcc      816
 Thr Ser Ser Glu Pro Ser Pro Arg Ile Arg Gly Val Ala Val Asp Ser
             260                 265                 270

 aaa atg aaa tgc cac cta tgt ggt gcc act gtg gga gat ctt gtt ccc      864
 Lys Met Lys Cys His Leu Cys Gly Ala Thr Val Gly Asp Leu Val Pro
         275                 280                 285

 aac aca tag                                                          873
 Asn Thr 
     290





      <210> 653
      <211> 135
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(135)

      <400> 653
  atg acc ctc ctg ctg ctg ccc ctt ctg ctg gcc tct ctg ctc gcg tcc      48
  Met Thr Leu Leu Leu Leu Pro Leu Leu Leu Ala Ser Leu Leu Ala Ser
    1               5                  10                  15

 tgc tcc tgt aac aaa ggg cag gtt gtt tcc atg gga act gtc tac cct       96
 Cys Ser Cys Asn Lys Gly Gln Val Val Ser Met Gly Thr Val Tyr Pro
              20                  25                  30

 gct ata gga gaa ggc tat gac ctc ccg cag acc ctc tga                  135
 Ala Ile Gly Glu Gly Tyr Asp Leu Pro Gln Thr Leu 
          35                  40





      <210> 654
      <211> 363
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(363)

      <400> 654
  atg cga ctt tgg ctg ctg ctg tcg cgc gtc ccg ccg ggc tca cta cac      48
  Met Arg Leu Trp Leu Leu Leu Ser Arg Val Pro Pro Gly Ser Leu His
    1               5                  10                  15

 gcc tta ccg gtc cgg gga cgc gac gcg aac ccc tca gtc ccc acg gca       96
 Ala Leu Pro Val Arg Gly Arg Asp Ala Asn Pro Ser Val Pro Thr Ala
              20                  25                  30

 gac ccc gag ccg gga aag acg gcg ccc gga gcc agc cgg gag ctg agc      144
 Asp Pro Glu Pro Gly Lys Thr Ala Pro Gly Ala Ser Arg Glu Leu Ser
          35                  40                  45

 agc agc ggc cga gga gga aga agc agc tgc ggc ggc cac acc ctg gat      192
 Ser Ser Gly Arg Gly Gly Arg Ser Ser Cys Gly Gly His Thr Leu Asp
      50                  55                  60

 gag gtg aga gca tgg cca gct cct gcc tct gga gcc cgg gag gct gag      240
 Glu Val Arg Ala Trp Pro Ala Pro Ala Ser Gly Ala Arg Glu Ala Glu
  65                  70                  75                  80

 gaa cgc gat ggg ggt ggc aac gca cga gct gga gcc ctg cct gat ggc      288
 Glu Arg Asp Gly Gly Gly Asn Ala Arg Ala Gly Ala Leu Pro Asp Gly
                  85                  90                  95

 tgg atg gag gcc atg cag gac aag ttc ctt cta aaa tca atc ctt tgc      336
 Trp Met Glu Ala Met Gln Asp Lys Phe Leu Leu Lys Ser Ile Leu Cys
             100                 105                 110

 ttt ggc ctg gaa gac cga aca tat tag                                  363
 Phe Gly Leu Glu Asp Arg Thr Tyr 
         115                 120





      <210> 655
      <211> 543
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(543)

      <400> 655
  atg ctc act cag aac agc aga gtg aac cta cag gag gaa gca ata gtc      48
  Met Leu Thr Gln Asn Ser Arg Val Asn Leu Gln Glu Glu Ala Ile Val
    1               5                  10                  15

 ggg ggt tct ctg ata gct ccc ttc ttc ctg gtg cta gtg ttt gag ctg       96
 Gly Gly Ser Leu Ile Ala Pro Phe Phe Leu Val Leu Val Phe Glu Leu
              20                  25                  30

 ctg tat gtg ttt gag ctg ctg tat gct ggt gtt gtg cgt gca tgt gaa      144
 Leu Tyr Val Phe Glu Leu Leu Tyr Ala Gly Val Val Arg Ala Cys Glu
          35                  40                  45

 gag ttg atg ctt tca ttg gaa act cag gga aaa tgg gct aca gag cag      192
 Glu Leu Met Leu Ser Leu Glu Thr Gln Gly Lys Trp Ala Thr Glu Gln
      50                  55                  60

 atg gag aag atc tgc ctg cac tgc aag tgt ccc cag gag gag cac atg      240
 Met Glu Lys Ile Cys Leu His Cys Lys Cys Pro Gln Glu Glu His Met
  65                  70                  75                  80

 gtg aca gtg atg ccg ctg gag atg gag aag acc atc agc aaa ctc atg      288
 Val Thr Val Met Pro Leu Glu Met Glu Lys Thr Ile Ser Lys Leu Met
                  85                  90                  95

 ttt gac ttt cag agg aac tcg acc tca gat gat gac tca ggc tgt gct      336
 Phe Asp Phe Gln Arg Asn Ser Thr Ser Asp Asp Asp Ser Gly Cys Ala
             100                 105                 110

 ttg gaa gag tat gcc tgg gtc ccg ccg ggt ctg aag cct gaa cag gcc      384
 Leu Glu Glu Tyr Ala Trp Val Pro Pro Gly Leu Lys Pro Glu Gln Ala
         115                 120                 125

 ttc tgc tgt ggg att gtt ata aag ata caa gtt cgt ccc agt gga gtt      432
 Phe Cys Cys Gly Ile Val Ile Lys Ile Gln Val Arg Pro Ser Gly Val
     130                 135                 140

 ctc tgg ctc tgt gga gcc tgt gga agt tat tca ggg ccc cag atg gag      480
 Leu Trp Leu Cys Gly Ala Cys Gly Ser Tyr Ser Gly Pro Gln Met Glu
 145                 150                 155                 160

 cct ctt gat tct gaa tcc tct aat gcc cca agc agg ctt tgg gat tat      528
 Pro Leu Asp Ser Glu Ser Ser Asn Ala Pro Ser Arg Leu Trp Asp Tyr
                 165                 170                 175

 ctg ctg aag tac tga                                                  543
 Leu Leu Lys Tyr 
             180





      <210> 656
      <211> 363
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(363)

      <400> 656
  atg cag ctg ctg ggt ttc agc aag aaa gtg atg ata ata aag ctg ctc      48
  Met Gln Leu Leu Gly Phe Ser Lys Lys Val Met Ile Ile Lys Leu Leu
    1               5                  10                  15

 cta agg aag gct gat ctg gag tgg aac atg ggt tgg aca ggt cag ggt       96
 Leu Arg Lys Ala Asp Leu Glu Trp Asn Met Gly Trp Thr Gly Gln Gly
              20                  25                  30

 atg gag gga gga gga gaa gcc aga ggg aag tgg tgg agc ata gcg gtt      144
 Met Glu Gly Gly Gly Glu Ala Arg Gly Lys Trp Trp Ser Ile Ala Val
          35                  40                  45

 aat aac aca ggc tct gga gct att atg gcc aga gcc aaa cct gga tct      192
 Asn Asn Thr Gly Ser Gly Ala Ile Met Ala Arg Ala Lys Pro Gly Ser
      50                  55                  60

 gcc atc ttc ggt ttg act gaa gga agg atg ctt caa cta aat cca gcc      240
 Ala Ile Phe Gly Leu Thr Glu Gly Arg Met Leu Gln Leu Asn Pro Ala
  65                  70                  75                  80

 aaa agc tgg gag gca gcc cag ctt ggg tca gtt ttc atc ctt gta cca      288
 Lys Ser Trp Glu Ala Ala Gln Leu Gly Ser Val Phe Ile Leu Val Pro
                  85                  90                  95

 gtc agg cct agc ttg ctg aga atg gcc aca tgg aaa aag caa ggc ttc      336
 Val Arg Pro Ser Leu Leu Arg Met Ala Thr Trp Lys Lys Gln Gly Phe
             100                 105                 110

 tgg gca gcc ctt tcc atg gtc cct tag                                  363
 Trp Ala Ala Leu Ser Met Val Pro 
         115                 120





      <210> 657
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 657
  atg gcg ccc tgg acg ctg tct cgc tgc tgc cac tgc gtc atg ggc tgg      48
  Met Ala Pro Trp Thr Leu Ser Arg Cys Cys His Cys Val Met Gly Trp
    1               5                  10                  15

 gtg ccg gtg ctc ctc atc acc ttc gtg gtc atc tgg tcc tac tac gcg       96
 Val Pro Val Leu Leu Ile Thr Phe Val Val Ile Trp Ser Tyr Tyr Ala
              20                  25                  30

 tac gtg gtg gag ctg tgc gtg ttt act att ttt gga aat gaa gaa aat      144
 Tyr Val Val Glu Leu Cys Val Phe Thr Ile Phe Gly Asn Glu Glu Asn
          35                  40                  45

 gga aag acc gtg ttt tac ctt aat tct act tgt cca att ctg aaa agg      192
 Gly Lys Thr Val Phe Tyr Leu Asn Ser Thr Cys Pro Ile Leu Lys Arg
      50                  55                  60

 aac gtt atg gaa aag aat tca gcc aag aaa gac aac aag aaa ttt tga      240
 Asn Val Met Glu Lys Asn Ser Ala Lys Lys Asp Asn Lys Lys Phe 
  65                  70                  75





      <210> 658
      <211> 816
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(816)

      <400> 658
  atg ctg gca gtc ctc aca gcc ttc gct cgc tct cgg cgc ctc ctc tgc      48
  Met Leu Ala Val Leu Thr Ala Phe Ala Arg Ser Arg Arg Leu Leu Cys
    1               5                  10                  15

 ctg ggc tcc cac ttt ggc cgc act tca gga gcc ctt cag ccc act gct       96
 Leu Gly Ser His Phe Gly Arg Thr Ser Gly Ala Leu Gln Pro Thr Ala
              20                  25                  30

 gca ctg tgg gag ccc ctt tct ggg ctg gcc aag acc gga gcc gtc tcc      144
 Ala Leu Trp Glu Pro Leu Ser Gly Leu Ala Lys Thr Gly Ala Val Ser
          35                  40                  45

 ctc agc ttg cag gga gac ttg tca cag act tta tct tca gta gta ggt      192
 Leu Ser Leu Gln Gly Asp Leu Ser Gln Thr Leu Ser Ser Val Val Gly
      50                  55                  60

 aga gac agg aat gct aag aaa gga gag atg atc atg ctg gta aat gtg      240
 Arg Asp Arg Asn Ala Lys Lys Gly Glu Met Ile Met Leu Val Asn Val
  65                  70                  75                  80

 gct gga acc cat gca aat ggg ctt tct cca cat gat gga gaa gat ggc      288
 Ala Gly Thr His Ala Asn Gly Leu Ser Pro His Asp Gly Glu Asp Gly
                  85                  90                  95

 tgc cag gac atc agc cat att gga tta ggg cac act caa gtg att tca      336
 Cys Gln Asp Ile Ser His Ile Gly Leu Gly His Thr Gln Val Ile Ser
             100                 105                 110

 ttt cac ttt aac tac ctc ctt aaa ggc cct atc ttc aca tac acc cat      384
 Phe His Phe Asn Tyr Leu Leu Lys Gly Pro Ile Phe Thr Tyr Thr His
         115                 120                 125

 att ccc agg gac tgg aga act gca act tcc agt gag tcc ctc tgt gtg      432
 Ile Pro Arg Asp Trp Arg Thr Ala Thr Ser Ser Glu Ser Leu Cys Val
     130                 135                 140

 tct gga tca ggg aat gca att aaa gcc gag tac ttc gag tca cct ttt      480
 Ser Gly Ser Gly Asn Ala Ile Lys Ala Glu Tyr Phe Glu Ser Pro Phe
 145                 150                 155                 160

 aaa aac agt gaa gcc acg aat gaa acg aca gtc ctt gct cca cat gaa      528
 Lys Asn Ser Glu Ala Thr Asn Glu Thr Thr Val Leu Ala Pro His Glu
                 165                 170                 175

 aca atc ttt cga gcc gaa gat cta tct gtg att ctt aaa gcg tat gtg      576
 Thr Ile Phe Arg Ala Glu Asp Leu Ser Val Ile Leu Lys Ala Tyr Val
             180                 185                 190

 ttg gtg acg tcc tta acc cct ttg cgt gca ttc att cat tcg acg ggc      624
 Leu Val Thr Ser Leu Thr Pro Leu Arg Ala Phe Ile His Ser Thr Gly
         195                 200                 205

 aca gtt tgg aat cca cca aag aaa aaa cgc ttc act gtc aag cct gct      672
 Thr Val Trp Asn Pro Pro Lys Lys Lys Arg Phe Thr Val Lys Pro Ala
     210                 215                 220

 tct ccc tgg agc cat caa ggg aag gta tat gct ggg atg agg atg gga      720
 Ser Pro Trp Ser His Gln Gly Lys Val Tyr Ala Gly Met Arg Met Gly
 225                 230                 235                 240

 ccc agt tat gga ctt gaa aag agc aag tgt tgt ttc tct gaa ctg gat      768
 Pro Ser Tyr Gly Leu Glu Lys Ser Lys Cys Cys Phe Ser Glu Leu Asp
                 245                 250                 255

 cct gga agt gta ttg ccc gtg aac ttc aca gaa gct ctt aaa aat taa      816
 Pro Gly Ser Val Leu Pro Val Asn Phe Thr Glu Ala Leu Lys Asn 
             260                 265                 270





      <210> 659
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 659
  atg ctc acc agt gct ttc ctc ttc atc ctg act ctg cct ttt gcc cac      48
  Met Leu Thr Ser Ala Phe Leu Phe Ile Leu Thr Leu Pro Phe Ala His
    1               5                  10                  15

 tca tct ttc aag ctg aat gtc acc tcc tca gag aag ccc tcc ctg act       96
 Ser Ser Phe Lys Leu Asn Val Thr Ser Ser Glu Lys Pro Ser Leu Thr
              20                  25                  30

 ccc aag ctc agg aat atg caa gca gag tcc aga acg cca ttt ggt ttg      144
 Pro Lys Leu Arg Asn Met Gln Ala Glu Ser Arg Thr Pro Phe Gly Leu
          35                  40                  45

 gat att gtg gaa gaa tcc ctg tat ctg aag gaa ttg cag tag              186
 Asp Ile Val Glu Glu Ser Leu Tyr Leu Lys Glu Leu Gln 
      50                  55                  60





      <210> 660
      <211> 534
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(534)

      <400> 660
  atg gct gcg cgc cac ctc ggg gct ccc gga gcc ctc gcg gca gtg ctg      48
  Met Ala Ala Arg His Leu Gly Ala Pro Gly Ala Leu Ala Ala Val Leu
    1               5                  10                  15

 gga act ccg gcc ctg ccc cgt cgg cgg tca cga ccc ctt atg aac ttc       96
 Gly Thr Pro Ala Leu Pro Arg Arg Arg Ser Arg Pro Leu Met Asn Phe
              20                  25                  30

 gac cgc cca gca aac agc ggc agg tgg aag agg gag aac tgt ccg ctc      144
 Asp Arg Pro Ala Asn Ser Gly Arg Trp Lys Arg Glu Asn Cys Pro Leu
          35                  40                  45

 cct gaa ggg gct ggc aaa aga gag gtg aag aca cag gcg gcg ggg acc      192
 Pro Glu Gly Ala Gly Lys Arg Glu Val Lys Thr Gln Ala Ala Gly Thr
      50                  55                  60

 gtc agg gac gct cgc gta cct tcc ttt tgc ctg gcg gag ggt cag act      240
 Val Arg Asp Ala Arg Val Pro Ser Phe Cys Leu Ala Glu Gly Gln Thr
  65                  70                  75                  80

 agc gcc agc gga tcg cct cac atc cgg gta tca gga gac act cag ctg      288
 Ser Ala Ser Gly Ser Pro His Ile Arg Val Ser Gly Asp Thr Gln Leu
                  85                  90                  95

 ctt ctg ctg cgg ccg ccg cct ccc ccg cgg cgc aaa cac caa act tcc      336
 Leu Leu Leu Arg Pro Pro Pro Pro Pro Arg Arg Lys His Gln Thr Ser
             100                 105                 110

 ggc gac gac ggc gac gcc tcg ctc gtc aga tgg gag tta cct gtg acc      384
 Gly Asp Asp Gly Asp Ala Ser Leu Val Arg Trp Glu Leu Pro Val Thr
         115                 120                 125

 gtc ttg ggt gcg ctt gcg caa cgc tcc tct tca gcc cta acc ggc tca      432
 Val Leu Gly Ala Leu Ala Gln Arg Ser Ser Ser Ala Leu Thr Gly Ser
     130                 135                 140

 gct gac gtg ccc aga aga cga aga tgg ccg cca cgc tca ctg cgt gtc      480
 Ala Asp Val Pro Arg Arg Arg Arg Trp Pro Pro Arg Ser Leu Arg Val
 145                 150                 155                 160

 acg cag ttt ttc acc ccg gcc cgg acg gct ggg cgt cga gga aag gcg      528
 Thr Gln Phe Phe Thr Pro Ala Arg Thr Ala Gly Arg Arg Gly Lys Ala
                 165                 170                 175

 agc tag                                                              534
 Ser 






      <210> 661
      <211> 711
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(711)

      <400> 661
  atg ggt aag agc tgg ctg ttg cca gtg ctg ctg gct gtg tac ttc atc      48
  Met Gly Lys Ser Trp Leu Leu Pro Val Leu Leu Ala Val Tyr Phe Ile
    1               5                  10                  15

 ctt gtt tat tgg gag gag ctc tct gtt gcc cca ggc aat ggg ctg aaa       96
 Leu Val Tyr Trp Glu Glu Leu Ser Val Ala Pro Gly Asn Gly Leu Lys
              20                  25                  30

 tcc cga gta cac att aat ctg agc tcc ctc agc cct agg ggt agg ggg      144
 Ser Arg Val His Ile Asn Leu Ser Ser Leu Ser Pro Arg Gly Arg Gly
          35                  40                  45

 att ggg ggc aca aga tgg gtg cag cca gat agg gaa gat tcc ccc agt      192
 Ile Gly Gly Thr Arg Trp Val Gln Pro Asp Arg Glu Asp Ser Pro Ser
      50                  55                  60

 gtt gtc ctg ctc cca gtc cag gtt tgg gaa aat gct ggc agc gtt tcc      240
 Val Val Leu Leu Pro Val Gln Val Trp Glu Asn Ala Gly Ser Val Ser
  65                  70                  75                  80

 ctg tgt ctt tcc ccc aca aag tct cca agt ctc ttc tca aat gag ctc      288
 Leu Cys Leu Ser Pro Thr Lys Ser Pro Ser Leu Phe Ser Asn Glu Leu
                  85                  90                  95

 caa ggc ttg gga aaa aca atc tct tcc tct gcc cgg gtt gca tgg atc      336
 Gln Gly Leu Gly Lys Thr Ile Ser Ser Ser Ala Arg Val Ala Trp Ile
             100                 105                 110

 tcc agt gga aag aca cca tca cat tct tat act gca ttg tgg gcc att      384
 Ser Ser Gly Lys Thr Pro Ser His Ser Tyr Thr Ala Leu Trp Ala Ile
         115                 120                 125

 cta ctg act aaa tct gct tct gtg tta agg act ttc atg aac ctg tct      432
 Leu Leu Thr Lys Ser Ala Ser Val Leu Arg Thr Phe Met Asn Leu Ser
     130                 135                 140

 cat gac tgg ccc ttt cta aag gga agt atg gga gtt agt tac ttt aat      480
 His Asp Trp Pro Phe Leu Lys Gly Ser Met Gly Val Ser Tyr Phe Asn
 145                 150                 155                 160

 gca cat ttc cca atg ggt aag gaa cag tct gtg aac tta tat tgc atg      528
 Ala His Phe Pro Met Gly Lys Glu Gln Ser Val Asn Leu Tyr Cys Met
                 165                 170                 175

 aca tta caa ggc aaa gta tta att gat gta ttc gac agt cca cct ctg      576
 Thr Leu Gln Gly Lys Val Leu Ile Asp Val Phe Asp Ser Pro Pro Leu
             180                 185                 190

 tat gat gat gta aaa gtg cat ttt ttc tct tcg ctt tat cta cca aga      624
 Tyr Asp Asp Val Lys Val His Phe Phe Ser Ser Leu Tyr Leu Pro Arg
         195                 200                 205

 aat gaa ttg gat aat cca cat aaa caa aaa gct tgg aca att tat cca      672
 Asn Glu Leu Asp Asn Pro His Lys Gln Lys Ala Trp Thr Ile Tyr Pro
     210                 215                 220

 cca gaa ttt gcc gtg gag ata ctt ttt ggc aag aaa tga                  711
 Pro Glu Phe Ala Val Glu Ile Leu Phe Gly Lys Lys 
 225                 230                 235





      <210> 662
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 662
  atg cct cgc cct gct ttg gct cgc gca cgg tgc gtg cac cca ctg acc      48
  Met Pro Arg Pro Ala Leu Ala Arg Ala Arg Cys Val His Pro Leu Thr
    1               5                  10                  15

 tgc gcc cac tgt ctg gca ctc cct agt gag atg aac ccg gta cct cag       96
 Cys Ala His Cys Leu Ala Leu Pro Ser Glu Met Asn Pro Val Pro Gln
              20                  25                  30

 atg gaa atg cag aaa tca cct gtg ttc tgc gtc gct cag gct ggg agc      144
 Met Glu Met Gln Lys Ser Pro Val Phe Cys Val Ala Gln Ala Gly Ser
          35                  40                  45

 tgt aga ccg gag ctg ttc ata ttc ggc cat ctt cga gaa gac tgt ttt      192
 Cys Arg Pro Glu Leu Phe Ile Phe Gly His Leu Arg Glu Asp Cys Phe
      50                  55                  60

 caa agc tgg att aga gat tga                                          213
 Gln Ser Trp Ile Arg Asp 
  65                  70





      <210> 663
      <211> 747
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(747)

      <400> 663
  atg gac ttt gta gct gta att aag gtt aca aac ctt aaa ata ggg cga      48
  Met Asp Phe Val Ala Val Ile Lys Val Thr Asn Leu Lys Ile Gly Arg
    1               5                  10                  15

 gca gct tta agt atc cag aac ttc cca ata aga tcc ctg ttg att gtc       96
 Ala Ala Leu Ser Ile Gln Asn Phe Pro Ile Arg Ser Leu Leu Ile Val
              20                  25                  30

 acc ttc ctt tgg acc ttg ctg gac gtt gaa cca ggg gag ctg gtt gag      144
 Thr Phe Leu Trp Thr Leu Leu Asp Val Glu Pro Gly Glu Leu Val Glu
          35                  40                  45

 ccc act cag act tcg gac cta cag aag tgt gag gtc cag act cag agt      192
 Pro Thr Gln Thr Ser Asp Leu Gln Lys Cys Glu Val Gln Thr Gln Ser
      50                  55                  60

 gaa gaa cgt gaa gat ctt gct gcc tca ggt gag aaa ctt aaa tgg atg      240
 Glu Glu Arg Glu Asp Leu Ala Ala Ser Gly Glu Lys Leu Lys Trp Met
  65                  70                  75                  80

 tca aat aaa ctc agt aat caa gaa cct ccg tca gca gct cct cgc ttc      288
 Ser Asn Lys Leu Ser Asn Gln Glu Pro Pro Ser Ala Ala Pro Arg Phe
                  85                  90                  95

 gca gat aaa gaa gta aag gcg acg gag gag aaa tgg aga gaa aag gga      336
 Ala Asp Lys Glu Val Lys Ala Thr Glu Glu Lys Trp Arg Glu Lys Gly
             100                 105                 110

 aga ctt act tgg ggg ccg aag gct cag cct gac tcc cgc ttc gga ctc      384
 Arg Leu Thr Trp Gly Pro Lys Ala Gln Pro Asp Ser Arg Phe Gly Leu
         115                 120                 125

 ggc agg tgt cta gca ccg cgg gcc cag gcg gaa ggc gct ggc gca gcg      432
 Gly Arg Cys Leu Ala Pro Arg Ala Gln Ala Glu Gly Ala Gly Ala Ala
     130                 135                 140

 cag agc agg gac tcc act tat cga gga ctg gaa act ccc ctt gcc gcc      480
 Gln Ser Arg Asp Ser Thr Tyr Arg Gly Leu Glu Thr Pro Leu Ala Ala
 145                 150                 155                 160

 cgg cct ccg cgc tgc gct cct tgc tgt cac cgc tcc gag cga cgc agg      528
 Arg Pro Pro Arg Cys Ala Pro Cys Cys His Arg Ser Glu Arg Arg Arg
                 165                 170                 175

 cac gct ccc cgc tgc ctc cta gtc ctg gag aca gaa gga aat ttg aga      576
 His Ala Pro Arg Cys Leu Leu Val Leu Glu Thr Glu Gly Asn Leu Arg
             180                 185                 190

 cac aga aga gga aaa ggg aat gtg acc aca gag aca aag att gga atg      624
 His Arg Arg Gly Lys Gly Asn Val Thr Thr Glu Thr Lys Ile Gly Met
         195                 200                 205

 atg cag tca caa gcc aat gaa tgg cag cag cca cca gaa gct gga aga      672
 Met Gln Ser Gln Ala Asn Glu Trp Gln Gln Pro Pro Glu Ala Gly Arg
     210                 215                 220

 ggc aag gaa gga att ctc tcc aag agc ttc tca agg aag cac aat cct      720
 Gly Lys Glu Gly Ile Leu Ser Lys Ser Phe Ser Arg Lys His Asn Pro
 225                 230                 235                 240

 gct ttc ata ttg att tct gtc cag tga                                  747
 Ala Phe Ile Leu Ile Ser Val Gln 
                 245





      <210> 664
      <211> 642
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(642)

      <400> 664
  atg cgt ttc tgt ggt ttt cct ggt ttg ggg aaa gcg ggt aaa tgg tgg      48
  Met Arg Phe Cys Gly Phe Pro Gly Leu Gly Lys Ala Gly Lys Trp Trp
    1               5                  10                  15

 ctg gtt gcg gct aac tgg gcc gcg cta aaa ggt aac cca agg cag gtg       96
 Leu Val Ala Ala Asn Trp Ala Ala Leu Lys Gly Asn Pro Arg Gln Val
              20                  25                  30

 gat tac ctg ggg aaa cag ctg gag cag tgg tcc tgg gcc gcc agt ccg      144
 Asp Tyr Leu Gly Lys Gln Leu Glu Gln Trp Ser Trp Ala Ala Ser Pro
          35                  40                  45

 cgg tca tcc cgg gag ctt aag atg cgg agt ggt gat agg ctc cgg atg      192
 Arg Ser Ser Arg Glu Leu Lys Met Arg Ser Gly Asp Arg Leu Arg Met
      50                  55                  60

 tat gag ccc tgt ggc tca agg gcg ctg ttc tct ctg ctc cga aat aga      240
 Tyr Glu Pro Cys Gly Ser Arg Ala Leu Phe Ser Leu Leu Arg Asn Arg
  65                  70                  75                  80

 aat aat acc tgt ctc aca gag ctg ttg aaa agc tcc act gaa ata atg      288
 Asn Asn Thr Cys Leu Thr Glu Leu Leu Lys Ser Ser Thr Glu Ile Met
                  85                  90                  95

 acc gca agt gtg aac tgt aaa gca atg aga gac gtg gcc gat aga agc      336
 Thr Ala Ser Val Asn Cys Lys Ala Met Arg Asp Val Ala Asp Arg Ser
             100                 105                 110

 cga gtg gca gta act cta agt tgg agt tac acg gtg gag aag gaa gca      384
 Arg Val Ala Val Thr Leu Ser Trp Ser Tyr Thr Val Glu Lys Glu Ala
         115                 120                 125

 ctg act cag act cgg gaa ata ttt cca tgc aaa cgc tgt cct cat gtg      432
 Leu Thr Gln Thr Arg Glu Ile Phe Pro Cys Lys Arg Cys Pro His Val
     130                 135                 140

 gtc gga acc agt tac ttc aaa gaa gat att cca gtg gaa tat aaa ata      480
 Val Gly Thr Ser Tyr Phe Lys Glu Asp Ile Pro Val Glu Tyr Lys Ile
 145                 150                 155                 160

 att tgt gtt act atg gaa aga gac caa ggc tca aca ctc aag ttt caa      528
 Ile Cys Val Thr Met Glu Arg Asp Gln Gly Ser Thr Leu Lys Phe Gln
                 165                 170                 175

 ggc tgc ctc tcc cca ccg aag act ggc ttg ctg gcg gca gtg gaa gga      576
 Gly Cys Leu Ser Pro Pro Lys Thr Gly Leu Leu Ala Ala Val Glu Gly
             180                 185                 190

 agg gga acc gaa gac agg agg aca tgg ctg gcc agg cca gct ctg gct      624
 Arg Gly Thr Glu Asp Arg Arg Thr Trp Leu Ala Arg Pro Ala Leu Ala
         195                 200                 205

 gta aca act gtc atg tga                                              642
 Val Thr Thr Val Met 
     210





      <210> 665
      <211> 693
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(693)

      <400> 665
  atg gaa gtg gct gcc ttt ggc aag cag aaa tta aga gtg gcg tgg agt      48
  Met Glu Val Ala Ala Phe Gly Lys Gln Lys Leu Arg Val Ala Trp Ser
    1               5                  10                  15

 cta cag gtg cta ttc cgg ctt atg gct gtt gaa ata tgg aac agc aaa       96
 Leu Gln Val Leu Phe Arg Leu Met Ala Val Glu Ile Trp Asn Ser Lys
              20                  25                  30

 ccg gct gtc att cat aag aat tgg tgc cgg cca gct ggc caa gcc aac      144
 Pro Ala Val Ile His Lys Asn Trp Cys Arg Pro Ala Gly Gln Ala Asn
          35                  40                  45

 tac agg aat aaa gac gtg cct ttt cac tct gat aca cgg ggc ctt gct      192
 Tyr Arg Asn Lys Asp Val Pro Phe His Ser Asp Thr Arg Gly Leu Ala
      50                  55                  60

 ctg agc aga cag ctg aag aat ctc aga gtc act aag gga cct gaa tac      240
 Leu Ser Arg Gln Leu Lys Asn Leu Arg Val Thr Lys Gly Pro Glu Tyr
  65                  70                  75                  80

 cag gag gag ggt cta gaa atg gaa aga agt gga gct cag att gag aac      288
 Gln Glu Glu Gly Leu Glu Met Glu Arg Ser Gly Ala Gln Ile Glu Asn
                  85                  90                  95

 caa ctg gag aaa gga tct ctg gtc ctg aac atc aaa acg tac aac aag      336
 Gln Leu Glu Lys Gly Ser Leu Val Leu Asn Ile Lys Thr Tyr Asn Lys
             100                 105                 110

 ggg gag aga aca gga caa aat gca tca gtg gaa atg agt aaa act gaa      384
 Gly Glu Arg Thr Gly Gln Asn Ala Ser Val Glu Met Ser Lys Thr Glu
         115                 120                 125

 gga gca gga ggc tgc tgg gga aaa gag cag cat cca gtt gga ctt ccc      432
 Gly Ala Gly Gly Cys Trp Gly Lys Glu Gln His Pro Val Gly Leu Pro
     130                 135                 140

 cga acc aca ggc ccc atg cag tcc tcc gtg ccc cca ggc tca ggt ggc      480
 Arg Thr Thr Gly Pro Met Gln Ser Ser Val Pro Pro Gly Ser Gly Gly
 145                 150                 155                 160

 atg gtc tca gga gcc agt ccc gca ggc ccc ggc ttc ctg ggc agc cag      528
 Met Val Ser Gly Ala Ser Pro Ala Gly Pro Gly Phe Leu Gly Ser Gln
                 165                 170                 175

 ccc caa gca gcc atc atg aag cag atg ctc att gat cag cgg gcc cag      576
 Pro Gln Ala Ala Ile Met Lys Gln Met Leu Ile Asp Gln Arg Ala Gln
             180                 185                 190

 ttg ata gag cag cag aag caa cag ttc ctg cgg gag caa agg cag cag      624
 Leu Ile Glu Gln Gln Lys Gln Gln Phe Leu Arg Glu Gln Arg Gln Gln
         195                 200                 205

 cag cag cag cag cag cag cag att ttg gcg gaa cag tat cta aag gaa      672
 Gln Gln Gln Gln Gln Gln Gln Ile Leu Ala Glu Gln Tyr Leu Lys Glu
     210                 215                 220

 caa gat tcc gca gac gtt tga                                          693
 Gln Asp Ser Ala Asp Val 
 225                 230





      <210> 666
      <211> 309
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(309)

      <400> 666
  atg gcc aga ccc cac act cat ttg ctc atg caa ccc ttg ctg ctc tgc      48
  Met Ala Arg Pro His Thr His Leu Leu Met Gln Pro Leu Leu Leu Cys
    1               5                  10                  15

 acc tgg ctt gcc ctt ggc agg cat ggg atc tgg acc agt agt gaa aga       96
 Thr Trp Leu Ala Leu Gly Arg His Gly Ile Trp Thr Ser Ser Glu Arg
              20                  25                  30

 caa gca cag cct gcc agg cca agt ggg tgg aag gag ccc agt ggg ccc      144
 Gln Ala Gln Pro Ala Arg Pro Ser Gly Trp Lys Glu Pro Ser Gly Pro
          35                  40                  45

 aag caa aac tca ggg tat gtt tcc tac atc gac aga aga ttc cca ctg      192
 Lys Gln Asn Ser Gly Tyr Val Ser Tyr Ile Asp Arg Arg Phe Pro Leu
      50                  55                  60

 aag act ggt tcc cgg gtt ccc atc ttg gat gat gag gga aac aag tca      240
 Lys Thr Gly Ser Arg Val Pro Ile Leu Asp Asp Glu Gly Asn Lys Ser
  65                  70                  75                  80

 aga act gat gcc aac tac gat ttt gag cct ctg gaa cca gtg aac tct      288
 Arg Thr Asp Ala Asn Tyr Asp Phe Glu Pro Leu Glu Pro Val Asn Ser
                  85                  90                  95

 gtt tcc aag cag ctt atg tga                                          309
 Val Ser Lys Gln Leu Met 
             100





      <210> 667
      <211> 282
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(282)

      <400> 667
  atg gtg ccg ctg tgc cag gta agg gtg gcg ggt gtg cgt gcg ggc ctg      48
  Met Val Pro Leu Cys Gln Val Arg Val Ala Gly Val Arg Ala Gly Leu
    1               5                  10                  15

 gcc ttg gtc agt cgg acc tcc cca cta gcc ccc aac ctg gcc ggc gtc       96
 Ala Leu Val Ser Arg Thr Ser Pro Leu Ala Pro Asn Leu Ala Gly Val
              20                  25                  30

 ttg ggt tcg ggg gcg ccc ccg ccc ccg ccc ccg ggc cct tcc tgt ctc      144
 Leu Gly Ser Gly Ala Pro Pro Pro Pro Pro Pro Gly Pro Ser Cys Leu
          35                  40                  45

 cgg gct tta ctg cga ctg ccc cag cag aag tcg ggt cct ctc cga gaa      192
 Arg Ala Leu Leu Arg Leu Pro Gln Gln Lys Ser Gly Pro Leu Arg Glu
      50                  55                  60

 ctc ttg tca gct cac ggc agc aag gac gga ctc gtt ctg aag gcg cct      240
 Leu Leu Ser Ala His Gly Ser Lys Asp Gly Leu Val Leu Lys Ala Pro
  65                  70                  75                  80

 cca cct ttt atg acc acc tct ttc cca gat tat tcg ttt tga              282
 Pro Pro Phe Met Thr Thr Ser Phe Pro Asp Tyr Ser Phe 
                  85                  90





      <210> 668
      <211> 768
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(768)

      <400> 668
  atg aag gca ctc ctg gcc ctg ccg ctg ctg ctg ctt ctc tcc acg ccc      48
  Met Lys Ala Leu Leu Ala Leu Pro Leu Leu Leu Leu Leu Ser Thr Pro
    1               5                  10                  15

 ccg tgt gcc ccc cag gtc tcc ggg atc cga gga gat gct ctg gag agg       96
 Pro Cys Ala Pro Gln Val Ser Gly Ile Arg Gly Asp Ala Leu Glu Arg
              20                  25                  30

 ttt tgc ctt cag caa ccc ctg gac tgt gac gac atc tat gcc cag ggc      144
 Phe Cys Leu Gln Gln Pro Leu Asp Cys Asp Asp Ile Tyr Ala Gln Gly
          35                  40                  45

 tac cag tca gac ggc gtg tac ctc atc tac ccc tcg ggc ccc agt gtg      192
 Tyr Gln Ser Asp Gly Val Tyr Leu Ile Tyr Pro Ser Gly Pro Ser Val
      50                  55                  60

 cct gtg ccc gtc ttc tgt gac atg acc acc gag ggc ggg aag tgg acg      240
 Pro Val Pro Val Phe Cys Asp Met Thr Thr Glu Gly Gly Lys Trp Thr
  65                  70                  75                  80

 gtt ttc cag aag aga ttc aat ggc tca gta agt ttc ttc cgc ggc tgg      288
 Val Phe Gln Lys Arg Phe Asn Gly Ser Val Ser Phe Phe Arg Gly Trp
                  85                  90                  95

 aat gac tac aag ctg ggc ttc ggc cgt gct gat gga gag tac tgg ctg      336
 Asn Asp Tyr Lys Leu Gly Phe Gly Arg Ala Asp Gly Glu Tyr Trp Leu
             100                 105                 110

 ggg ctg cag aac atg cac ctc ctg aca ctg aag cag aag tat gag ctg      384
 Gly Leu Gln Asn Met His Leu Leu Thr Leu Lys Gln Lys Tyr Glu Leu
         115                 120                 125

 cga gtg gac ttg gag gac ttt gag aac aac acg gcc tat gcc aag tac      432
 Arg Val Asp Leu Glu Asp Phe Glu Asn Asn Thr Ala Tyr Ala Lys Tyr
     130                 135                 140

 gct gac ttc tcc atc tcc ccg aac gcg gtc agc gca gag gag gat ggc      480
 Ala Asp Phe Ser Ile Ser Pro Asn Ala Val Ser Ala Glu Glu Asp Gly
 145                 150                 155                 160

 tac acc ctc ttt gtg gca ggc ttt gag gat ggc ggg gca ggt gac tcc      528
 Tyr Thr Leu Phe Val Ala Gly Phe Glu Asp Gly Gly Ala Gly Asp Ser
                 165                 170                 175

 ctg tcc tac cac agt ggc cag aag ttc tct acc ttc gac cgg gac cag      576
 Leu Ser Tyr His Ser Gly Gln Lys Phe Ser Thr Phe Asp Arg Asp Gln
             180                 185                 190

 gac ctc ttt gtg cag aac tgc gca gct ctc tcc tca gga gcc ttc tgg      624
 Asp Leu Phe Val Gln Asn Cys Ala Ala Leu Ser Ser Gly Ala Phe Trp
         195                 200                 205

 ttc cgc agc tgc cac ttt gcc aac ctc aat ggc ttc tac cta ggt ggc      672
 Phe Arg Ser Cys His Phe Ala Asn Leu Asn Gly Phe Tyr Leu Gly Gly
     210                 215                 220

 tcc cac ctc tct tat gcc aat ggc atc aac tgg gcc cag tgg aag ggc      720
 Ser His Leu Ser Tyr Ala Asn Gly Ile Asn Trp Ala Gln Trp Lys Gly
 225                 230                 235                 240

 ttc tac tac tcc ctc aaa cgc act gag atg aaa atc cgc cgg gcc tga      768
 Phe Tyr Tyr Ser Leu Lys Arg Thr Glu Met Lys Ile Arg Arg Ala 
                 245                 250                 255





      <210> 669
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 669
  atg ctc ctg ggc aca gct gca gct tcc cag ctg tgg ctc tgg gcc cat      48
  Met Leu Leu Gly Thr Ala Ala Ala Ser Gln Leu Trp Leu Trp Ala His
    1               5                  10                  15

 gca tcc ctg cgc tct cag ggg ccg gga agc ccc cag tgc cca cag gct       96
 Ala Ser Leu Arg Ser Gln Gly Pro Gly Ser Pro Gln Cys Pro Gln Ala
              20                  25                  30

 cag aag tgc ctg ttc ctg ctc cct gtc ctc ttc cca ctc ctg gtg cct      144
 Gln Lys Cys Leu Phe Leu Leu Pro Val Leu Phe Pro Leu Leu Val Pro
          35                  40                  45

 gct cct gtg tgg agc aaa gtt gtg gcc aag cct ggg cgc tgc tgc aac      192
 Ala Pro Val Trp Ser Lys Val Val Ala Lys Pro Gly Arg Cys Cys Asn
      50                  55                  60

 ctg gcc aga ctt tgg gtg ctg acg agc aca ggc atg gga tct gag gtg      240
 Leu Ala Arg Leu Trp Val Leu Thr Ser Thr Gly Met Gly Ser Glu Val
  65                  70                  75                  80

 gta gtg tga                                                          249
 Val Val 






      <210> 670
      <211> 1032
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1032)

      <400> 670
  atg ctg agc tgg gcc agc acc ggt ggg ctc cga ctg atg gct gcg atg      48
  Met Leu Ser Trp Ala Ser Thr Gly Gly Leu Arg Leu Met Ala Ala Met
    1               5                  10                  15

 gct ttc ttt att tgt gtg ggc aga gtg gtc agt cag tgg gag gat gat       96
 Ala Phe Phe Ile Cys Val Gly Arg Val Val Ser Gln Trp Glu Asp Asp
              20                  25                  30

 gat gag ggt gag gac atg aca acg aag cac ggc ttt ggt ttc ctg ctg      144
 Asp Glu Gly Glu Asp Met Thr Thr Lys His Gly Phe Gly Phe Leu Leu
          35                  40                  45

 cag ctg ctg ctg ggg agt tat cag ggc att tcc tcc gcc tgt gag ctc      192
 Gln Leu Leu Leu Gly Ser Tyr Gln Gly Ile Ser Ser Ala Cys Glu Leu
      50                  55                  60

 ctg gga gca aga ctc cgt ctc aaa aac aac aac aac aac aac aac aac      240
 Leu Gly Ala Arg Leu Arg Leu Lys Asn Asn Asn Asn Asn Asn Asn Asn
  65                  70                  75                  80

 aac aac aac aac aac aac aac aaa gtg ctg gcg gga tgt ttc tac gtg      288
 Asn Asn Asn Asn Asn Asn Asn Lys Val Leu Ala Gly Cys Phe Tyr Val
                  85                  90                  95

 ttc atc aaa ccg gct ttg ttt act tcc gaa aca ctc atg aag acc aca      336
 Phe Ile Lys Pro Ala Leu Phe Thr Ser Glu Thr Leu Met Lys Thr Thr
             100                 105                 110

 gct gcc aga gcc cct tgc atc ctg gtg gga ctg tgc gac tac ttc tgg      384
 Ala Ala Arg Ala Pro Cys Ile Leu Val Gly Leu Cys Asp Tyr Phe Trp
         115                 120                 125

 ccc atg gat gcc tgg ctc ctg gac ccc acc gac ggc ttc tca cct gta      432
 Pro Met Asp Ala Trp Leu Leu Asp Pro Thr Asp Gly Phe Ser Pro Val
     130                 135                 140

 acc cca cca gcc ttc tac ctg gat act tca cgg gga gct aga gtg gcc      480
 Thr Pro Pro Ala Phe Tyr Leu Asp Thr Ser Arg Gly Ala Arg Val Ala
 145                 150                 155                 160

 ttg gct aag aag gag gca tgg cac ccg cgg cgg ccc ggg ccc gct gca      528
 Leu Ala Lys Lys Glu Ala Trp His Pro Arg Arg Pro Gly Pro Ala Ala
                 165                 170                 175

 gcc gcc gcc ggc gcc gaa ctt ggg ctc ggg aag ccg gcg gac cgc gtc      576
 Ala Ala Ala Gly Ala Glu Leu Gly Leu Gly Lys Pro Ala Asp Arg Val
             180                 185                 190

 ctg cgc cgg agc agc acc tcc cgg gcg gcg ccg cct ccg cga gtg ccc      624
 Leu Arg Arg Ser Ser Thr Ser Arg Ala Ala Pro Pro Pro Arg Val Pro
         195                 200                 205

 gag agc gcc gcg ctg ggc gcc ggc cct gcc cca gcc ccc agg ctc ccg      672
 Glu Ser Ala Ala Leu Gly Ala Gly Pro Ala Pro Ala Pro Arg Leu Pro
     210                 215                 220

 cgc aag cgt ggg ggt ccc tct cct ggc cgg gag gca gcg act gcg gag      720
 Arg Lys Arg Gly Gly Pro Ser Pro Gly Arg Glu Ala Ala Thr Ala Glu
 225                 230                 235                 240

 ttg aga acc ctt tgg ttc aac aag ttc cta gtc cgg gag gat gca gct      768
 Leu Arg Thr Leu Trp Phe Asn Lys Phe Leu Val Arg Glu Asp Ala Ala
                 245                 250                 255

 cag ctc gtg gag tcc gag agt cac ggc gta aaa ttg gcg ctt ccc gca      816
 Gln Leu Val Glu Ser Glu Ser His Gly Val Lys Leu Ala Leu Pro Ala
             260                 265                 270

 cat gca gat ctc ggg ctc ccg ggg tgt ccc ggc cgc caa agg cca ccc      864
 His Ala Asp Leu Gly Leu Pro Gly Cys Pro Gly Arg Gln Arg Pro Pro
         275                 280                 285

 ctt tcc tcc tgg ctg acc cca att cca cca gag gag gat gtt tgc cag      912
 Leu Ser Ser Trp Leu Thr Pro Ile Pro Pro Glu Glu Asp Val Cys Gln
     290                 295                 300

 gga cgc cga gtc cag ctg ctg gcc tcg gca tta gac aac ccc cag ccc      960
 Gly Arg Arg Val Gln Leu Leu Ala Ser Ala Leu Asp Asn Pro Gln Pro
 305                 310                 315                 320

 cag ccc ctg cca tcc ctg ctc cct tgc agc cag cct cat gcc ggg ggt     1008
 Gln Pro Leu Pro Ser Leu Leu Pro Cys Ser Gln Pro His Ala Gly Gly
                 325                 330                 335

 gcc aca tgg gac acc tcc tcc tag                                     1032
 Ala Thr Trp Asp Thr Ser Ser 
             340





      <210> 671
      <211> 180
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(180)

      <400> 671
  atg cag agc ctt gga gtt gtc ctc tac gtg ctt gtg tgc ggt gcc ctg      48
  Met Gln Ser Leu Gly Val Val Leu Tyr Val Leu Val Cys Gly Ala Leu
    1               5                  10                  15

 cca ttt gat gga agc aca ctg cag aat ctg cgg gcc cgc gtg ctg agt       96
 Pro Phe Asp Gly Ser Thr Leu Gln Asn Leu Arg Ala Arg Val Leu Ser
              20                  25                  30

 gga aag ttc cgc atc cca ttt ttt atg tcc aca gat ttg ctc tat tct      144
 Gly Lys Phe Arg Ile Pro Phe Phe Met Ser Thr Asp Leu Leu Tyr Ser
          35                  40                  45

 gta ttt gct gcc tta gtg aat agc atc acc atc tga                      180
 Val Phe Ala Ala Leu Val Asn Ser Ile Thr Ile 
      50                  55





      <210> 672
      <211> 456
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(456)

      <400> 672
  atg aaa ttg ctt gga atc atc cag aga caa cca ttg tta gtg atc tgt      48
  Met Lys Leu Leu Gly Ile Ile Gln Arg Gln Pro Leu Leu Val Ile Cys
    1               5                  10                  15

 gtg gcc ttg gga ttt gtc ttg gct gtt act atg aca cgg gaa gca att       96
 Val Ala Leu Gly Phe Val Leu Ala Val Thr Met Thr Arg Glu Ala Ile
              20                  25                  30

 gat gaa ttt cgg cgt ttt cag cgt gac aag gaa gtg aat tca caa cta      144
 Asp Glu Phe Arg Arg Phe Gln Arg Asp Lys Glu Val Asn Ser Gln Leu
          35                  40                  45

 tat agc aag ctt aca gaa atc ttt gtc aga aca ctg gct gaa tat aag      192
 Tyr Ser Lys Leu Thr Glu Ile Phe Val Arg Thr Leu Ala Glu Tyr Lys
      50                  55                  60

 aat gga aga gag act tta gag acc atc cat gat aaa gaa tac aca ctt      240
 Asn Gly Arg Glu Thr Leu Glu Thr Ile His Asp Lys Glu Tyr Thr Leu
  65                  70                  75                  80

 tac aaa aat agt gta gaa aaa tca gta gac aac aca gct aca gca tgt      288
 Tyr Lys Asn Ser Val Glu Lys Ser Val Asp Asn Thr Ala Thr Ala Cys
                  85                  90                  95

 aac aat aaa atc aac cca gaa gag gga gaa ata gct aat ttc cag aat      336
 Asn Asn Lys Ile Asn Pro Glu Glu Gly Glu Ile Ala Asn Phe Gln Asn
             100                 105                 110

 tac cag att ata ata gta agt aga gtc att ggc atg gca tgt ggt gag      384
 Tyr Gln Ile Ile Ile Val Ser Arg Val Ile Gly Met Ala Cys Gly Glu
         115                 120                 125

 cac tca gtg aac tgc ggg agt caa gaa aga aag aag ttc cag atc cag      432
 His Ser Val Asn Cys Gly Ser Gln Glu Arg Lys Lys Phe Gln Ile Gln
     130                 135                 140

 atg aaa gtg ctg agc ctg gtc taa                                      456
 Met Lys Val Leu Ser Leu Val 
 145                 150





      <210> 673
      <211> 885
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(885)

      <400> 673
  atg atg gtc tgg tgg ttt ttt tcc ctg ctg aac ctc atc acc tcc aac      48
  Met Met Val Trp Trp Phe Phe Ser Leu Leu Asn Leu Ile Thr Ser Asn
    1               5                  10                  15

 ggc cac act atg gat cgc tgc cgc cag ggg ggc ggg gaa tac gag gtc       96
 Gly His Thr Met Asp Arg Cys Arg Gln Gly Gly Gly Glu Tyr Glu Val
              20                  25                  30

 ttt gct gta ttg caa ggc aga acg ctt ttt ctc gag agg tat ata ttc      144
 Phe Ala Val Leu Gln Gly Arg Thr Leu Phe Leu Glu Arg Tyr Ile Phe
          35                  40                  45

 aac gga agt gga tac ata tgt tca ccg aaa gcc ttg aac aag gat att      192
 Asn Gly Ser Gly Tyr Ile Cys Ser Pro Lys Ala Leu Asn Lys Asp Ile
      50                  55                  60

 cac agc agc gct att cct agt agc cac aga ctg aaa agt gat gag ctc      240
 His Ser Ser Ala Ile Pro Ser Ser His Arg Leu Lys Ser Asp Glu Leu
  65                  70                  75                  80

 tgc agt agg cga aat cag ttc cat ggt aag aca ggc tca gtg gta gca      288
 Cys Ser Arg Arg Asn Gln Phe His Gly Lys Thr Gly Ser Val Val Ala
                  85                  90                  95

 ggc agc ctg gaa ccc aaa ctc aca tgc aaa tgg aga aga tta tat ctc      336
 Gly Ser Leu Glu Pro Lys Leu Thr Cys Lys Trp Arg Arg Leu Tyr Leu
             100                 105                 110

 ttc cta aga ata ggc ttt gtt aaa gac gag aga aga aag caa gaa ggc      384
 Phe Leu Arg Ile Gly Phe Val Lys Asp Glu Arg Arg Lys Gln Glu Gly
         115                 120                 125

 cct gga aac cca aag agc atg tct gga aat ggg aag gaa ggg gag gag      432
 Pro Gly Asn Pro Lys Ser Met Ser Gly Asn Gly Lys Glu Gly Glu Glu
     130                 135                 140

 ggc aag ccc cct cga aga gaa aga gga aag caa aaa aac att aaa aga      480
 Gly Lys Pro Pro Arg Arg Glu Arg Gly Lys Gln Lys Asn Ile Lys Arg
 145                 150                 155                 160

 gag aac agc aga aga tac aag gcc aca aga ggg gaa aac aca tta gga      528
 Glu Asn Ser Arg Arg Tyr Lys Ala Thr Arg Gly Glu Asn Thr Leu Gly
                 165                 170                 175

 gaa gag agg agg aag ggg aca gtg gag gtg gag gtg aag gtg aag gtg      576
 Glu Glu Arg Arg Lys Gly Thr Val Glu Val Glu Val Lys Val Lys Val
             180                 185                 190

 gtg gtg atg gta gag gag gat aag gag gaa gat gat gaa ttc agt ttg      624
 Val Val Met Val Glu Glu Asp Lys Glu Glu Asp Asp Glu Phe Ser Leu
         195                 200                 205

 gga cag act aag ttc aac agc cta gaa agc atc tta ggc aac aga gtg      672
 Gly Gln Thr Lys Phe Asn Ser Leu Glu Ser Ile Leu Gly Asn Arg Val
     210                 215                 220

 aga ctc cat caa aag aag acg aag aag aaa aag aag aag aag aag aag      720
 Arg Leu His Gln Lys Lys Thr Lys Lys Lys Lys Lys Lys Lys Lys Lys
 225                 230                 235                 240

 aag aag aag aag gaa gag gag gag gaa gag aag gag gag gag gaa gaa      768
 Lys Lys Lys Lys Glu Glu Glu Glu Glu Glu Lys Glu Glu Glu Glu Glu
                 245                 250                 255

 gaa gaa gga gaa gac cac cag acc cct aaa tgt tgg cga atc cag ggc      816
 Glu Glu Gly Glu Asp His Gln Thr Pro Lys Cys Trp Arg Ile Gln Gly
             260                 265                 270

 cca gtg ctc agc ctg ctg ctc ttc tct gtc aac aca ctc cac tta tgc      864
 Pro Val Leu Ser Leu Leu Leu Phe Ser Val Asn Thr Leu His Leu Cys
         275                 280                 285

 gat ccc acc cag tcc cac tga                                          885
 Asp Pro Thr Gln Ser His 
     290





      <210> 674
      <211> 537
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(537)

      <400> 674
  atg ccc ggc tct gcc tac ttt aaa acg ctc atc tcc acc atc tgg atc      48
  Met Pro Gly Ser Ala Tyr Phe Lys Thr Leu Ile Ser Thr Ile Trp Ile
    1               5                  10                  15

 act tgg tgg ctt gct gct att ttc tgg ttt tcc ggc cct cag tcc tat       96
 Thr Trp Trp Leu Ala Ala Ile Phe Trp Phe Ser Gly Pro Gln Ser Tyr
              20                  25                  30

 cac cca gga ctt agc ttg gta att tcc atg tcg gga aga gag gac tca      144
 His Pro Gly Leu Ser Leu Val Ile Ser Met Ser Gly Arg Glu Asp Ser
          35                  40                  45

 cag tcc aca gaa gca gca gct ggg ata gaa atg tct ccc act cac atc      192
 Gln Ser Thr Glu Ala Ala Ala Gly Ile Glu Met Ser Pro Thr His Ile
      50                  55                  60

 tca gta tgt tgg gtc tcc tcg atg ccc atg agc agt gtg aaa ggg gca      240
 Ser Val Cys Trp Val Ser Ser Met Pro Met Ser Ser Val Lys Gly Ala
  65                  70                  75                  80

 gtg gct tgc aga ctt tgg atg ccc ttc agg aag gca gcc tct cag cca      288
 Val Ala Cys Arg Leu Trp Met Pro Phe Arg Lys Ala Ala Ser Gln Pro
                  85                  90                  95

 ctt gtt tct tct aaa aat gaa gag atg gag gag aaa aag aag cag gaa      336
 Leu Val Ser Ser Lys Asn Glu Glu Met Glu Glu Lys Lys Lys Gln Glu
             100                 105                 110

 gag aag gag gaa gag gaa agg aag aaa ggg agg gag aga ggg agg gag      384
 Glu Lys Glu Glu Glu Glu Arg Lys Lys Gly Arg Glu Arg Gly Arg Glu
         115                 120                 125

 gaa gag gaa gag gaa agg aag aaa ggg agg gag aga ggg agg gag gaa      432
 Glu Glu Glu Glu Glu Arg Lys Lys Gly Arg Glu Arg Gly Arg Glu Glu
     130                 135                 140

 gag gaa gag gag gag aaa aga aag gaa aag aaa aga aac cat cag gtg      480
 Glu Glu Glu Glu Glu Lys Arg Lys Glu Lys Lys Arg Asn His Gln Val
 145                 150                 155                 160

 aat tat gaa gtg ggt gga gac caa act cta aat agt gct tcc agg tgc      528
 Asn Tyr Glu Val Gly Gly Asp Gln Thr Leu Asn Ser Ala Ser Arg Cys
                 165                 170                 175

 ctc gaa tga                                                          537
 Leu Glu 






      <210> 675
      <211> 696
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(696)

      <400> 675
  atg gcc tcc agg tgg gca cag gcg ctc tgc ctg ctc ggg ggc acg gta      48
  Met Ala Ser Arg Trp Ala Gln Ala Leu Cys Leu Leu Gly Gly Thr Val
    1               5                  10                  15

 ccg ggt cag ccc aca ccg ctg tca gca ggc gag gca gcc agg tca ggg       96
 Pro Gly Gln Pro Thr Pro Leu Ser Ala Gly Glu Ala Ala Arg Ser Gly
              20                  25                  30

 caa tca ctt agt aac caa ttt caa cct gtt tcc tca gtt gta aag tgg      144
 Gln Ser Leu Ser Asn Gln Phe Gln Pro Val Ser Ser Val Val Lys Trp
          35                  40                  45

 gat gaa aga gcc tac cca caa aaa gac tat gcc ctg ggt ggc cgc tgg      192
 Asp Glu Arg Ala Tyr Pro Gln Lys Asp Tyr Ala Leu Gly Gly Arg Trp
      50                  55                  60

 gcc cag aat gat gaa gat ggg gcc aac ctg aac cca acc tgc aac ctg      240
 Ala Gln Asn Asp Glu Asp Gly Ala Asn Leu Asn Pro Thr Cys Asn Leu
  65                  70                  75                  80

 gag atg atc ccg gcc aac ccg gag agc tgt att cgc ttt tta gga gaa      288
 Glu Met Ile Pro Ala Asn Pro Glu Ser Cys Ile Arg Phe Leu Gly Glu
                  85                  90                  95

 gac agg agc atg att cgc agg gct gct atg aca att tgg gaa cgt gag      336
 Asp Arg Ser Met Ile Arg Arg Ala Ala Met Thr Ile Trp Glu Arg Glu
             100                 105                 110

 cat ccc cca ggt cag aac gtc cca gca gct gag caa aaa ctt gcg gcc      384
 His Pro Pro Gly Gln Asn Val Pro Ala Ala Glu Gln Lys Leu Ala Ala
         115                 120                 125

 aca gat cct caa tgg gat agt aac aac gca gcc tac tgg agg aat atg      432
 Thr Asp Pro Gln Trp Asp Ser Asn Asn Ala Ala Tyr Trp Arg Asn Met
     130                 135                 140

 caa gac ctt gga gaa ctg ata att aaa gga act caa aaa tct gta ttc      480
 Gln Asp Leu Gly Glu Leu Ile Ile Lys Gly Thr Gln Lys Ser Val Phe
 145                 150                 155                 160

 cgc atc caa aac att ccc aaa gct ttc tat ata caa caa ggg aag gat      528
 Arg Ile Gln Asn Ile Pro Lys Ala Phe Tyr Ile Gln Gln Gly Lys Asp
                 165                 170                 175

 gaa gga cct aca gag ttc tta gaa agg ctc aag gag caa gcg agg ata      576
 Glu Gly Pro Thr Glu Phe Leu Glu Arg Leu Lys Glu Gln Ala Arg Ile
             180                 185                 190

 tat gca ggt cta ggt tta gaa gac cct ctt ggg cag ggg atg tta aag      624
 Tyr Ala Gly Leu Gly Leu Glu Asp Pro Leu Gly Gln Gly Met Leu Lys
         195                 200                 205

 ctc cat ttt gtt acc aat agt tgg cca gac atc aca aaa cac gtt ata      672
 Leu His Phe Val Thr Asn Ser Trp Pro Asp Ile Thr Lys His Val Ile
     210                 215                 220

 gaa aat aga gaa ctg gaa aga taa                                      696
 Glu Asn Arg Glu Leu Glu Arg 
 225                 230





      <210> 676
      <211> 258
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(258)

      <400> 676
  atg gcc tcc agg tgg gca cag gcg ctc tgc ctg ctc ggg ggc acg gta      48
  Met Ala Ser Arg Trp Ala Gln Ala Leu Cys Leu Leu Gly Gly Thr Val
    1               5                  10                  15

 ccg ggt cag ccc aca ccg ctg tca gca ggc gag gca gcc agt tta gtt       96
 Pro Gly Gln Pro Thr Pro Leu Ser Ala Gly Glu Ala Ala Ser Leu Val
              20                  25                  30

 ggg tgt gac agg atc cgc ctg gac ttg gca gag tac ggt ttt act ttc      144
 Gly Cys Asp Arg Ile Arg Leu Asp Leu Ala Glu Tyr Gly Phe Thr Phe
          35                  40                  45

 cag agt gta aaa gag aaa ttt gtg gac ttc aga aaa gca ttt ggt gtt      192
 Gln Ser Val Lys Glu Lys Phe Val Asp Phe Arg Lys Ala Phe Gly Val
      50                  55                  60

 cta ggg aac tgc agc tgt cag ctt tta aag atg cca tgt gtt tgc cca      240
 Leu Gly Asn Cys Ser Cys Gln Leu Leu Lys Met Pro Cys Val Cys Pro
  65                  70                  75                  80

 cat aaa gga atg caa tga                                              258
 His Lys Gly Met Gln 
                  85





      <210> 677
      <211> 804
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(804)

      <400> 677
  atg gcg gaa agc aaa gca gaa atg gct ggt cca aac acg cgt atc tgg      48
  Met Ala Glu Ser Lys Ala Glu Met Ala Gly Pro Asn Thr Arg Ile Trp
    1               5                  10                  15

 cat ctg ctg agc agg ttc ttg ctg tcc tgc ttc ttt ggc gct ttc caa       96
 His Leu Leu Ser Arg Phe Leu Leu Ser Cys Phe Phe Gly Ala Phe Gln
              20                  25                  30

 acg gca gaa ttc cag tgc tgt cct ctg gca ggt aga tgt ctc cgc cat      144
 Thr Ala Glu Phe Gln Cys Cys Pro Leu Ala Gly Arg Cys Leu Arg His
          35                  40                  45

 gga aag ggc ttc cac ata tcc tgt ggg gca ggc acg ggg caa ggt gct      192
 Gly Lys Gly Phe His Ile Ser Cys Gly Ala Gly Thr Gly Gln Gly Ala
      50                  55                  60

 gga gag gag aag gtg acc ttg aca gat gct gtc cct gcc ctg tgg agc      240
 Gly Glu Glu Lys Val Thr Leu Thr Asp Ala Val Pro Ala Leu Trp Ser
  65                  70                  75                  80

 tcc tgg gtt ggc tca aag gcc atc gtc aca cag cat ggg aat gac agt      288
 Ser Trp Val Gly Ser Lys Ala Ile Val Thr Gln His Gly Asn Asp Ser
                  85                  90                  95

 ctg gaa caa ctc aac aag caa cct cat att tta att gtg aac aca gag      336
 Leu Glu Gln Leu Asn Lys Gln Pro His Ile Leu Ile Val Asn Thr Glu
             100                 105                 110

 act ctg aag gtg gtg aac tcg ccg gaa ctc acg aag tca cgg aag ctg      384
 Thr Leu Lys Val Val Asn Ser Pro Glu Leu Thr Lys Ser Arg Lys Leu
         115                 120                 125

 gaa gca aac gtg ccc tgt ggg gct gaa gcc gca agc tcc ctg tca tct      432
 Glu Ala Asn Val Pro Cys Gly Ala Glu Ala Ala Ser Ser Leu Ser Ser
     130                 135                 140

 ccg gcc cta gtc aga ggt aac tgg aac att ctg gga gtt gtg gta atg      480
 Pro Ala Leu Val Arg Gly Asn Trp Asn Ile Leu Gly Val Val Val Met
 145                 150                 155                 160

 gta tgt ttg ggg caa tca gag gtg ctg gtc aga agg aaa gtg aag gaa      528
 Val Cys Leu Gly Gln Ser Glu Val Leu Val Arg Arg Lys Val Lys Glu
                 165                 170                 175

 gac act ctg ttc ctc aat cac att gac cct ctc tgg gtg tcc cag gga      576
 Asp Thr Leu Phe Leu Asn His Ile Asp Pro Leu Trp Val Ser Gln Gly
             180                 185                 190

 aaa gcg ggc agc atg cct cga agg gcc cat gga aca cag gga gct gtc      624
 Lys Ala Gly Ser Met Pro Arg Arg Ala His Gly Thr Gln Gly Ala Val
         195                 200                 205

 gag aca tac gca gtc aac cgt gag aaa cct agc acc caa cgt cat cat      672
 Glu Thr Tyr Ala Val Asn Arg Glu Lys Pro Ser Thr Gln Arg His His
     210                 215                 220

 ggt att tac cat gtt gca ata cag aaa gca ttt gga gaa ttg cta atc      720
 Gly Ile Tyr His Val Ala Ile Gln Lys Ala Phe Gly Glu Leu Leu Ile
 225                 230                 235                 240

 tat tcc act gtg aaa aac aac ctg ctg aga aat gct gct tcc acc cag      768
 Tyr Ser Thr Val Lys Asn Asn Leu Leu Arg Asn Ala Ala Ser Thr Gln
                 245                 250                 255

 caa cct gct gcc ttg aat aac cag aaa acg aaa taa                      804
 Gln Pro Ala Ala Leu Asn Asn Gln Lys Thr Lys 
             260                 265





      <210> 678
      <211> 291
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(291)

      <400> 678
  atg gtg gtc ccc att ttt caa gtg ctc acc ctg tgc tct cta cca agt      48
  Met Val Val Pro Ile Phe Gln Val Leu Thr Leu Cys Ser Leu Pro Ser
    1               5                  10                  15

 gct ttc tgc gcc acc tcc atc aat gat cac aag aac ccc agc gag gcg       96
 Ala Phe Cys Ala Thr Ser Ile Asn Asp His Lys Asn Pro Ser Glu Ala
              20                  25                  30

 gca ctg ctg act gcc tgc cca att cca cag gac tgg aga gtg gcc act      144
 Ala Leu Leu Thr Ala Cys Pro Ile Pro Gln Asp Trp Arg Val Ala Thr
          35                  40                  45

 gca ggg gag ccc aag ggg aca acc cgg ctg ccc ggc ccg cca gct ccc      192
 Ala Gly Glu Pro Lys Gly Thr Thr Arg Leu Pro Gly Pro Pro Ala Pro
      50                  55                  60

 ggc agt gct ggc ttc gga aag aga gag aaa gaa cag aaa gca aaa ctt      240
 Gly Ser Ala Gly Phe Gly Lys Arg Glu Lys Glu Gln Lys Ala Lys Leu
  65                  70                  75                  80

 cct ggc ggc cga cgg cca tca gct gca cat tct gca aat gcc acc gag      288
 Pro Gly Gly Arg Arg Pro Ser Ala Ala His Ser Ala Asn Ala Thr Glu
                  85                  90                  95

 taa                                                                  291
 






      <210> 679
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 679
  atg aaa tgc cac ttg tgc tgc ttt ctg ttg gtt aaa gtc cag ctc act      48
  Met Lys Cys His Leu Cys Cys Phe Leu Leu Val Lys Val Gln Leu Thr
    1               5                  10                  15

 cac tta act cac atc ttt gtc atc tat gcc ttt ctc tat gga aat ttt       96
 His Leu Thr His Ile Phe Val Ile Tyr Ala Phe Leu Tyr Gly Asn Phe
              20                  25                  30

 ctg gcg ctg acc tat ttc tgg cta tgg aac ctc tca act atg att tcc      144
 Leu Ala Leu Thr Tyr Phe Trp Leu Trp Asn Leu Ser Thr Met Ile Ser
          35                  40                  45

 tcc cct tgc tgg atc att cct gac agc aac tct cgg atg ctg cat tct      192
 Ser Pro Cys Trp Ile Ile Pro Asp Ser Asn Ser Arg Met Leu His Ser
      50                  55                  60

 ctg aag cac tta gat gct tag                                          213
 Leu Lys His Leu Asp Ala 
  65                  70





      <210> 680
      <211> 1116
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1116)

      <400> 680
  atg cag tcc cct agc cgc ggt ctc agg caa aat act tgt gtc tgc cta      48
  Met Gln Ser Pro Ser Arg Gly Leu Arg Gln Asn Thr Cys Val Cys Leu
    1               5                  10                  15

 ctc ctt tta tcc att gct cag tca ggg tct gag gga cgg acc tgg cag       96
 Leu Leu Leu Ser Ile Ala Gln Ser Gly Ser Glu Gly Arg Thr Trp Gln
              20                  25                  30

 gtg gtg ctc tgt gtg agg aat gct gcc atg gat tgt gac gga acc ccc      144
 Val Val Leu Cys Val Arg Asn Ala Ala Met Asp Cys Asp Gly Thr Pro
          35                  40                  45

 gaa aac aaa gtc ctg ctg tta cag ggc aaa aat acc aaa gag gaa acg      192
 Glu Asn Lys Val Leu Leu Leu Gln Gly Lys Asn Thr Lys Glu Glu Thr
      50                  55                  60

 gag gtt ttg cct aag ccc cct ccc aca ata aat tgg aag aaa gac aag      240
 Glu Val Leu Pro Lys Pro Pro Pro Thr Ile Asn Trp Lys Lys Asp Lys
  65                  70                  75                  80

 gga tac act ata gct atg gaa ccc tgt ctt agg caa gca gca tta gaa      288
 Gly Tyr Thr Ile Ala Met Glu Pro Cys Leu Arg Gln Ala Ala Leu Glu
                  85                  90                  95

 ggg gag ctc ttc gcc tgc ctg gta atg caa gat cga caa ggc aat cag      336
 Gly Glu Leu Phe Ala Cys Leu Val Met Gln Asp Arg Gln Gly Asn Gln
             100                 105                 110

 gta tat gaa ccc att tct tct gat gct gat aaa gag ata agg aaa agc      384
 Val Tyr Glu Pro Ile Ser Ser Asp Ala Asp Lys Glu Ile Arg Lys Ser
         115                 120                 125

 att aga gaa aac aga ggc act agt cca ctt aca aaa gga tta att gag      432
 Ile Arg Glu Asn Arg Gly Thr Ser Pro Leu Thr Lys Gly Leu Ile Glu
     130                 135                 140

 acc ata gca gac aac tta cat atg acc cca tgg gac tgg tca gtg cta      480
 Thr Ile Ala Asp Asn Leu His Met Thr Pro Trp Asp Trp Ser Val Leu
 145                 150                 155                 160

 gct aaa aca act tta aag ata gca gta tct gat tat gca ggc cat ata      528
 Ala Lys Thr Thr Leu Lys Ile Ala Val Ser Asp Tyr Ala Gly His Ile
                 165                 170                 175

 gaa cat gcc ctt cct gct gac aaa tta ctt cag ttc tta cct cat act      576
 Glu His Ala Leu Pro Ala Asp Lys Leu Leu Gln Phe Leu Pro His Thr
             180                 185                 190

 cct gta gtt atg cct aca aag gta gtt cac ttt ccc ata tct aac act      624
 Pro Val Val Met Pro Thr Lys Val Val His Phe Pro Ile Ser Asn Thr
         195                 200                 205

 tta atg ctt ttt gct gat ggc tct agt aaa aat gga aaa gca gct att      672
 Leu Met Leu Phe Ala Asp Gly Ser Ser Lys Asn Gly Lys Ala Ala Ile
     210                 215                 220

 ggt ggg aat ccc caa gga cag gcc ata gaa cat ggc cac tcc acc ctt      720
 Gly Gly Asn Pro Gln Gly Gln Ala Ile Glu His Gly His Ser Thr Leu
 225                 230                 235                 240

 aat atg ctc aat atg ctc act cgt tct gga ttt acc ttt act cag aga      768
 Asn Met Leu Asn Met Leu Thr Arg Ser Gly Phe Thr Phe Thr Gln Arg
                 245                 250                 255

 gct gag gtt gga gcc tta ata ttg gcc cta gaa aca ttt tct ttt cag      816
 Ala Glu Val Gly Ala Leu Ile Leu Ala Leu Glu Thr Phe Ser Phe Gln
             260                 265                 270

 ccc atc aat att gat agt gac tct gct tat gct gtt tat tta ttg cag      864
 Pro Ile Asn Ile Asp Ser Asp Ser Ala Tyr Ala Val Tyr Leu Leu Gln
         275                 280                 285

 aac ctt gag aca gcc ctc att gag tct gct ctg gag ccc aac cta tat      912
 Asn Leu Glu Thr Ala Leu Ile Glu Ser Ala Leu Glu Pro Asn Leu Tyr
     290                 295                 300

 gca ctt ttt ctt cag act tca gca att gct gat caa tca cga tgc atc      960
 Ala Leu Phe Leu Gln Thr Ser Ala Ile Ala Asp Gln Ser Arg Cys Ile
 305                 310                 315                 320

 aaa tca tac cat ggt gtg gct agg acc caa ccc agt agg aga aat gaa     1008
 Lys Ser Tyr His Gly Val Ala Arg Thr Gln Pro Ser Arg Arg Asn Glu
                 325                 330                 335

 ggg aat gac cct aca gga cct gca gcc ccg gat gat gca act tcc ttg     1056
 Gly Asn Asp Pro Thr Gly Pro Ala Ala Pro Asp Asp Ala Thr Ser Leu
             340                 345                 350

 gat gac acg agc cct gga cat tac ctg ggg gat gct gaa gat gac aac     1104
 Asp Asp Thr Ser Pro Gly His Tyr Leu Gly Asp Ala Glu Asp Asp Asn
         355                 360                 365

 cca gga ggc tga                                                     1116
 Pro Gly Gly 
     370





      <210> 681
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 681
  atg gtg ttc cac aca gca ttg cct ctg acc acg gca ctc act tta cgg      48
  Met Val Phe His Thr Ala Leu Pro Leu Thr Thr Ala Leu Thr Leu Arg
    1               5                  10                  15

 cta aag aag tgt ggc act gtg ctc ata ctc atg gaa ttc act ggt ctt       96
 Leu Lys Lys Cys Gly Thr Val Leu Ile Leu Met Glu Phe Thr Gly Leu
              20                  25                  30

 acc atg ttc ccc atc atc ctg aag cag ggc tgg ggc aaa gtt atc cag      144
 Thr Met Phe Pro Ile Ile Leu Lys Gln Gly Trp Gly Lys Val Ile Gln
          35                  40                  45

 agg gct gtg tat gct ctg aat cag cat cca ata tat ggt act gtt tct      192
 Arg Ala Val Tyr Ala Leu Asn Gln His Pro Ile Tyr Gly Thr Val Ser
      50                  55                  60

 ccc ata gcc agg att cac agg tcc aga aat caa ggg gtg gaa gtg gaa      240
 Pro Ile Ala Arg Ile His Arg Ser Arg Asn Gln Gly Val Glu Val Glu
  65                  70                  75                  80

 gtg gca cca ctc tcc atc acc tct aat gac aca cta gca aaa ttt ttg      288
 Val Ala Pro Leu Ser Ile Thr Ser Asn Asp Thr Leu Ala Lys Phe Leu
                  85                  90                  95

 ttt cct gtt ccc atg aca tta tat tct gct ggc cta gag gtc tca gtt      336
 Phe Pro Val Pro Met Thr Leu Tyr Ser Ala Gly Leu Glu Val Ser Val
             100                 105                 110

 cca gag gga gga atg ctg cca aca ggg gaa aca ata acg att caa ttt      384
 Pro Glu Gly Gly Met Leu Pro Thr Gly Glu Thr Ile Thr Ile Gln Phe
         115                 120                 125

 aac tgg aag tta aga ttg cca cct gga cac ttt tcc tac cta agt caa      432
 Asn Trp Lys Leu Arg Leu Pro Pro Gly His Phe Ser Tyr Leu Ser Gln
     130                 135                 140

 cag gct aag aag gga gtt aca gtg ttg gtt ggg gtg att ttc cca gac      480
 Gln Ala Lys Lys Gly Val Thr Val Leu Val Gly Val Ile Phe Pro Asp
 145                 150                 155                 160

 tat caa gat gaa atc agt cta cta cac cac agt gaa gct aag gaa gag      528
 Tyr Gln Asp Glu Ile Ser Leu Leu His His Ser Glu Ala Lys Glu Glu
                 165                 170                 175

 tat gtg tgg aat aca gga gtt agg gca tct ctt agt ttt acc atg ccc      576
 Tyr Val Trp Asn Thr Gly Val Arg Ala Ser Leu Ser Phe Thr Met Pro
             180                 185                 190

 tgt gat gag ggt cat tgg gaa act gca aca gcc cta ttc agg cag aac      624
 Cys Asp Glu Gly His Trp Glu Thr Ala Thr Ala Leu Phe Arg Gln Asn
         195                 200                 205

 tgc aaa tgg gtt cca gac ccc tca gga atg aag gtt tgg gtc act cca      672
 Cys Lys Trp Val Pro Asp Pro Ser Gly Met Lys Val Trp Val Thr Pro
     210                 215                 220

 cca ggt aaa aaa cca cga cct gct gag gtg ctt gct gaa gtc aaa ggg      720
 Pro Gly Lys Lys Pro Arg Pro Ala Glu Val Leu Ala Glu Val Lys Gly
 225                 230                 235                 240

 aat aca gaa tgg gta gta gaa taa                                      744
 Asn Thr Glu Trp Val Val Glu 
                 245





      <210> 682
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(498)

      <400> 682
  atg gca gag gca gat tcc aga tca tac ttc ttc ttg ccc ttc atc ttg      48
  Met Ala Glu Ala Asp Ser Arg Ser Tyr Phe Phe Leu Pro Phe Ile Leu
    1               5                  10                  15

 tcc ctg atc ttg ctg aag gga gac ctt ggc ttg tcc ttc atg gac agg       96
 Ser Leu Ile Leu Leu Lys Gly Asp Leu Gly Leu Ser Phe Met Asp Arg
              20                  25                  30

 tca aac ata ctg gcg ctc agg ttg ttg cgc gtg aac tgg atg cat ttg      144
 Ser Asn Ile Leu Ala Leu Arg Leu Leu Arg Val Asn Trp Met His Leu
          35                  40                  45

 gaa tac ggg atc ttc aac ttg cat gag gat tca atg gcc tat gcg tgg      192
 Glu Tyr Gly Ile Phe Asn Leu His Glu Asp Ser Met Ala Tyr Ala Trp
      50                  55                  60

 agc gct cag aac agg gcc cgg cac acg gga aac gca cac gag cat cgg      240
 Ser Ala Gln Asn Arg Ala Arg His Thr Gly Asn Ala His Glu His Arg
  65                  70                  75                  80

 ctc tca cat tca gca gct aag gga aca ggg ggc ctg gtg aag ggc aag      288
 Leu Ser His Ser Ala Ala Lys Gly Thr Gly Gly Leu Val Lys Gly Lys
                  85                  90                  95

 aag ctg gcc gaa ggc cct cag att ccc cag cgt cac gcc aca gtg ctc      336
 Lys Leu Ala Glu Gly Pro Gln Ile Pro Gln Arg His Ala Thr Val Leu
             100                 105                 110

 agg ctg acc ctc aaa tcc ttg cat gct gat gaa agc cac tgc ccc aac      384
 Arg Leu Thr Leu Lys Ser Leu His Ala Asp Glu Ser His Cys Pro Asn
         115                 120                 125

 ctc ttc caa aga cag gcc tta cct cag ctg gtg aac agc tac tac cac      432
 Leu Phe Gln Arg Gln Ala Leu Pro Gln Leu Val Asn Ser Tyr Tyr His
     130                 135                 140

 cct ggg gac aag gag cct gca aag ctg act gtt gta gga atc aag ccc      480
 Pro Gly Asp Lys Glu Pro Ala Lys Leu Thr Val Val Gly Ile Lys Pro
 145                 150                 155                 160

 cat ccc caa ggc aaa tga                                              498
 His Pro Gln Gly Lys 
                 165





      <210> 683
      <211> 456
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(456)

      <400> 683
  atg ggg agt act tcc agg cca ttg ctt att ttc act act tgc cta aag      48
  Met Gly Ser Thr Ser Arg Pro Leu Leu Ile Phe Thr Thr Cys Leu Lys
    1               5                  10                  15

 ctc ttc agt cag ctt gtg gtg aat gct tcc agg ctt gcg act cac cct       96
 Leu Phe Ser Gln Leu Val Val Asn Ala Ser Arg Leu Ala Thr His Pro
              20                  25                  30

 tca ggg cag tgg gct ccc atc tgg ccc atg gca ggt cca gaa atg cca      144
 Ser Gly Gln Trp Ala Pro Ile Trp Pro Met Ala Gly Pro Glu Met Pro
          35                  40                  45

 tcc aag agc caa ggc cta gaa ttg ggg cct cac aag gct gca cct gtg      192
 Ser Lys Ser Gln Gly Leu Glu Leu Gly Pro His Lys Ala Ala Pro Val
      50                  55                  60

 cca cag gcc acc atg gat ctg cac ctc gat gcc ctt cgg agt cat gag      240
 Pro Gln Ala Thr Met Asp Leu His Leu Asp Ala Leu Arg Ser His Glu
  65                  70                  75                  80

 agt gca agc aat agc agc tca gga agc agc agc aga gga gac cag aaa      288
 Ser Ala Ser Asn Ser Ser Ser Gly Ser Ser Ser Arg Gly Asp Gln Lys
                  85                  90                  95

 ggt cac tac ctt tgc atg aac aac aat ggc aac cag gat acc atg ctt      336
 Gly His Tyr Leu Cys Met Asn Asn Asn Gly Asn Gln Asp Thr Met Leu
             100                 105                 110

 ggt tct cca tgg tgt ggc cac ttt cct tcc cac aaa cct cac aca ggg      384
 Gly Ser Pro Trp Cys Gly His Phe Pro Ser His Lys Pro His Thr Gly
         115                 120                 125

 ctg cct ctg cgc ctg ttc cat agg tgt acc att aca agc aat gtc tgt      432
 Leu Pro Leu Arg Leu Phe His Arg Cys Thr Ile Thr Ser Asn Val Cys
     130                 135                 140

 att gct gct cca agc agc cag tga                                      456
 Ile Ala Ala Pro Ser Ser Gln 
 145                 150





      <210> 684
      <211> 1494
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1494)

      <400> 684
  atg gtg ttc ttc aca acc ctg ttc atc ctg gtt ggg gcc cca gca gcc      48
  Met Val Phe Phe Thr Thr Leu Phe Ile Leu Val Gly Ala Pro Ala Ala
    1               5                  10                  15

 ccc tct gtg aag cca cag cag cag cag gag cca ctg gct gct gtg cgc       96
 Pro Ser Val Lys Pro Gln Gln Gln Gln Glu Pro Leu Ala Ala Val Arg
              20                  25                  30

 cca cca ctg gga gac ctg agc acc aaa gac ctg ggt gat ccc tca atg      144
 Pro Pro Leu Gly Asp Leu Ser Thr Lys Asp Leu Gly Asp Pro Ser Met
          35                  40                  45

 gac aag gca gct gtg aag atc cag gct gcc ttt aag ggc tac aag gtc      192
 Asp Lys Ala Ala Val Lys Ile Gln Ala Ala Phe Lys Gly Tyr Lys Val
      50                  55                  60

 cgg aag gag atg aag cag cag gaa ggg ccc atg ttc tcc cac aca ttt      240
 Arg Lys Glu Met Lys Gln Gln Glu Gly Pro Met Phe Ser His Thr Phe
  65                  70                  75                  80

 ggg gac acc gag gca cag tgt gtc gtg gcc agc aag gca gat gtg cga      288
 Gly Asp Thr Glu Ala Gln Cys Val Val Ala Ser Lys Ala Asp Val Arg
                  85                  90                  95

 gcc cgc tgg ctg aag gat ggt gtg gag ctg acc gat ggg cgg cac cat      336
 Ala Arg Trp Leu Lys Asp Gly Val Glu Leu Thr Asp Gly Arg His His
             100                 105                 110

 cac atc gac cag ctt ggg gat ggc acc tgc tct ctg ctg atc act ggc      384
 His Ile Asp Gln Leu Gly Asp Gly Thr Cys Ser Leu Leu Ile Thr Gly
         115                 120                 125

 ctg ggc cgt gct gat gct ggc tgc tac acc tgt cag gtg agc aac aag      432
 Leu Gly Arg Ala Asp Ala Gly Cys Tyr Thr Cys Gln Val Ser Asn Lys
     130                 135                 140

 ttt ggc cag gtg acc cac agt gcc tgt gtg gtg gtc agt ggg tca gag      480
 Phe Gly Gln Val Thr His Ser Ala Cys Val Val Val Ser Gly Ser Glu
 145                 150                 155                 160

 agt gaa gcc gag agc tcc tct ggg ggt gag ctg gac gat gcc ttc cgc      528
 Ser Glu Ala Glu Ser Ser Ser Gly Gly Glu Leu Asp Asp Ala Phe Arg
                 165                 170                 175

 cgg gct gcc cgt cgg ctg cac cgg ctc ttc cgc acc aaa agt ccg gct      576
 Arg Ala Ala Arg Arg Leu His Arg Leu Phe Arg Thr Lys Ser Pro Ala
             180                 185                 190

 gaa gtt tca gat gag gag ctc ttc ctg agt gca gac gag ggc cct gca      624
 Glu Val Ser Asp Glu Glu Leu Phe Leu Ser Ala Asp Glu Gly Pro Ala
         195                 200                 205

 gag cca gag gag ccc gcg gac tgg cag aca tac cgc gaa gat gag cat      672
 Glu Pro Glu Glu Pro Ala Asp Trp Gln Thr Tyr Arg Glu Asp Glu His
     210                 215                 220

 ttc atc tgc atc cgt ttt gag gcg ctc act gag gcc gcc agg cgg aat      720
 Phe Ile Cys Ile Arg Phe Glu Ala Leu Thr Glu Ala Ala Arg Arg Asn
 225                 230                 235                 240

 gtt aaa gag gcc cca gtg ttc ctg act gag ttg cag aac caa gaa gtg      768
 Val Lys Glu Ala Pro Val Phe Leu Thr Glu Leu Gln Asn Gln Glu Val
                 245                 250                 255

 cag gat ggg tat cct gtg agc ttt gac tgc gtg gtg aca ggt cag ccc      816
 Gln Asp Gly Tyr Pro Val Ser Phe Asp Cys Val Val Thr Gly Gln Pro
             260                 265                 270

 atg ccc agt gtg cgc tgg ttc aag gat ggg aag ttg ttg gag gag gat      864
 Met Pro Ser Val Arg Trp Phe Lys Asp Gly Lys Leu Leu Glu Glu Asp
         275                 280                 285

 gat cac tac atg att aat gaa gac caa cag ggt ggc cat cag ctc atc      912
 Asp His Tyr Met Ile Asn Glu Asp Gln Gln Gly Gly His Gln Leu Ile
     290                 295                 300

 atc aca gcc gtg gtg cca gca gac atg ggc gtc tac cgc tgc ctg gcc      960
 Ile Thr Ala Val Val Pro Ala Asp Met Gly Val Tyr Arg Cys Leu Ala
 305                 310                 315                 320

 gag aac agc atg ggt gtc tcc tcc acc aag gct gag ctc cgt gtg gac     1008
 Glu Asn Ser Met Gly Val Ser Ser Thr Lys Ala Glu Leu Arg Val Asp
                 325                 330                 335

 tgt gag tac tgc gtc tgg ttt ggt gtc tcc agg cgc ggt gcg cgt ctt     1056
 Cys Glu Tyr Cys Val Trp Phe Gly Val Ser Arg Arg Gly Ala Arg Leu
             340                 345                 350

 cgt ggc aat cgc gag aag aga cgc gcg ctg ctg tac aag agg cac aac     1104
 Arg Gly Asn Arg Glu Lys Arg Arg Ala Leu Leu Tyr Lys Arg His Asn
         355                 360                 365

 ctg gcc cag gcc ctg gta gcc cct att cta ctt tct gtc gtt atg aac     1152
 Leu Ala Gln Ala Leu Val Ala Pro Ile Leu Leu Ser Val Val Met Asn
     370                 375                 380

 ttg act tcc ttt gat acc tca cca gca atc aac aca gaa gaa gat tct     1200
 Leu Thr Ser Phe Asp Thr Ser Pro Ala Ile Asn Thr Glu Glu Asp Ser
 385                 390                 395                 400

 gtg gcc aaa cct gtg agg ttt ctc ccc acc acc aag cag cag aca cca     1248
 Val Ala Lys Pro Val Arg Phe Leu Pro Thr Thr Lys Gln Gln Thr Pro
                 405                 410                 415

 gct ggg tgt cct cag tcc aat tcc aac act gtc tac ctg gag ata gta     1296
 Ala Gly Cys Pro Gln Ser Asn Ser Asn Thr Val Tyr Leu Glu Ile Val
             420                 425                 430

 aat ccc atc aaa ggt tct ggc cca ggc ttg ccc ctg ctc ctt tat acc     1344
 Asn Pro Ile Lys Gly Ser Gly Pro Gly Leu Pro Leu Leu Leu Tyr Thr
         435                 440                 445

 ccc tgg ctg acc ctg gtg ttt cct cag gtg gcc ctg gtg tcc tgg cat     1392
 Pro Trp Leu Thr Leu Val Phe Pro Gln Val Ala Leu Val Ser Trp His
     450                 455                 460

 gct cct tct ctt ggg aaa aaa cag aac cct cca atg gat aac agc aga     1440
 Ala Pro Ser Leu Gly Lys Lys Gln Asn Pro Pro Met Asp Asn Ser Arg
 465                 470                 475                 480

 atg aat gtt ctt ccc aat gca cgt gga gcc ttc tcc gga ttg gca atc     1488
 Met Asn Val Leu Pro Asn Ala Arg Gly Ala Phe Ser Gly Leu Ala Ile
                 485                 490                 495

 cac tag                                                             1494
 His 






      <210> 685
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 685
  atg ctt aac act ggg aat acc tta tta tta gtt ttc aga aca gtg aga      48
  Met Leu Asn Thr Gly Asn Thr Leu Leu Leu Val Phe Arg Thr Val Arg
    1               5                  10                  15

 gat aac tac tgt att ctt cat ttt gca gat gag gaa act cgt act aac       96
 Asp Asn Tyr Cys Ile Leu His Phe Ala Asp Glu Glu Thr Arg Thr Asn
              20                  25                  30

 aga aaa atg aag tta tta aaa aac agc atc tca gaa ttg aaa att ata      144
 Arg Lys Met Lys Leu Leu Lys Asn Ser Ile Ser Glu Leu Lys Ile Ile
          35                  40                  45

 aag aaa tct ggt ttg aac acc tac ctg aca ctt gaa ttc tct tta caa      192
 Lys Lys Ser Gly Leu Asn Thr Tyr Leu Thr Leu Glu Phe Ser Leu Gln
      50                  55                  60

 tat ccc taa                                                          201
 Tyr Pro 
  65





      <210> 686
      <211> 804
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(804)

      <400> 686
  atg gtg tgc tct cct gcc ctg acg tgc ctg cca gca acg ctc atg cac      48
  Met Val Cys Ser Pro Ala Leu Thr Cys Leu Pro Ala Thr Leu Met His
    1               5                  10                  15

 tgg gga ccc ccg gca att ggg ggg ccg ctc ttg ttg acc aaa tcg tcc       96
 Trp Gly Pro Pro Ala Ile Gly Gly Pro Leu Leu Leu Thr Lys Ser Ser
              20                  25                  30

 gca agt gta atc tca ata gcg gct ggt gac tct atg tcc ttc tcg ctg      144
 Ala Ser Val Ile Ser Ile Ala Ala Gly Asp Ser Met Ser Phe Ser Leu
          35                  40                  45

 ctt ggt ctt cta ctt gtc agc ccc ttc gta tca aag gtg aaa gga ctg      192
 Leu Gly Leu Leu Leu Val Ser Pro Phe Val Ser Lys Val Lys Gly Leu
      50                  55                  60

 cgt ctg cag aga gat gac ttt gag atc ttg aag gtg atc ggc cga gga      240
 Arg Leu Gln Arg Asp Asp Phe Glu Ile Leu Lys Val Ile Gly Arg Gly
  65                  70                  75                  80

 gcc ttt ggg gag gtc acc atg gtg agg cag agg gac act ggg cag att      288
 Ala Phe Gly Glu Val Thr Met Val Arg Gln Arg Asp Thr Gly Gln Ile
                  85                  90                  95

 ttt gcc atg aaa atg ctg cac aag tgg gag atg ctg aag agg gct gag      336
 Phe Ala Met Lys Met Leu His Lys Trp Glu Met Leu Lys Arg Ala Glu
             100                 105                 110

 aca gcc tgt ttc cgg gag gag cgg gat gtg ctc gtg aaa ggg gac agc      384
 Thr Ala Cys Phe Arg Glu Glu Arg Asp Val Leu Val Lys Gly Asp Ser
         115                 120                 125

 cgt tgg gtg acc act ctg cac tat gcc ttc caa gac gag gag tac ctg      432
 Arg Trp Val Thr Thr Leu His Tyr Ala Phe Gln Asp Glu Glu Tyr Leu
     130                 135                 140

 tac ctt gtg atg gac tac tat gct ggt ggg gac ctc ctg acg ctg ctg      480
 Tyr Leu Val Met Asp Tyr Tyr Ala Gly Gly Asp Leu Leu Thr Leu Leu
 145                 150                 155                 160

 agc cgc ttc gag gac cgt ctc ccg ccc gag ctg gcc cag ttc tac ctg      528
 Ser Arg Phe Glu Asp Arg Leu Pro Pro Glu Leu Ala Gln Phe Tyr Leu
                 165                 170                 175

 gct gag atg gtg ctg gcc atc cac tcg ctg cac cag ctg ggt tat gtc      576
 Ala Glu Met Val Leu Ala Ile His Ser Leu His Gln Leu Gly Tyr Val
             180                 185                 190

 cac agg gat gtc aag cca gac aac gtc ctg ctg gat gtg aac ggg cac      624
 His Arg Asp Val Lys Pro Asp Asn Val Leu Leu Asp Val Asn Gly His
         195                 200                 205

 att cgc ctg gct gac ttc ggc tcc tgc ctg cgt ctc aac acc aac ggc      672
 Ile Arg Leu Ala Asp Phe Gly Ser Cys Leu Arg Leu Asn Thr Asn Gly
     210                 215                 220

 atg gtg gat tca tca gtg gca gta ggg acg ccg gac tat atc tcc cct      720
 Met Val Asp Ser Ser Val Ala Val Gly Thr Pro Asp Tyr Ile Ser Pro
 225                 230                 235                 240

 gag atc ctg cag gcc atg gag gag ggc aag ggc cac tac ggc cca cag      768
 Glu Ile Leu Gln Ala Met Glu Glu Gly Lys Gly His Tyr Gly Pro Gln
                 245                 250                 255

 tgt gac tgg tgg tcg ctt gga ggt ctg cgc cta tga                      804
 Cys Asp Trp Trp Ser Leu Gly Gly Leu Arg Leu 
             260                 265





      <210> 687
      <211> 1119
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1119)

      <400> 687
  atg gct gtg cgc tct cgc cgc ccg tgg atg agc gtg gca tta ggg ctg      48
  Met Ala Val Arg Ser Arg Arg Pro Trp Met Ser Val Ala Leu Gly Leu
    1               5                  10                  15

 gtg ctg ggc ttc acc gcc gcg tcc tgg ctc atc gcc ccc agg gtg gcg       96
 Val Leu Gly Phe Thr Ala Ala Ser Trp Leu Ile Ala Pro Arg Val Ala
              20                  25                  30

 gag ctg agc gag agg aag aga cgt ggc tcc agc ctc tgc tcc tac tac      144
 Glu Leu Ser Glu Arg Lys Arg Arg Gly Ser Ser Leu Cys Ser Tyr Tyr
          35                  40                  45

 ggt cgc tct gct gct ggc ccc cgc gcc ggc gct cag cag ccg ctc ccc      192
 Gly Arg Ser Ala Ala Gly Pro Arg Ala Gly Ala Gln Gln Pro Leu Pro
      50                  55                  60

 cag ccc cag tcc cga cca cgg cag gag cag tcg ccg ccc ccc gcg cgc      240
 Gln Pro Gln Ser Arg Pro Arg Gln Glu Gln Ser Pro Pro Pro Ala Arg
  65                  70                  75                  80

 cag gat ctc cag ggg cca ccg ctg ccc gag gca gca ccc ggg atc acc      288
 Gln Asp Leu Gln Gly Pro Pro Leu Pro Glu Ala Ala Pro Gly Ile Thr
                  85                  90                  95

 agt ttt cga agc agc ccc tgg cag cag cca cct ccg ctg cag cag cgg      336
 Ser Phe Arg Ser Ser Pro Trp Gln Gln Pro Pro Pro Leu Gln Gln Arg
             100                 105                 110

 cgg cga gga cgc gag cct gag ggc gcg acg ggg ctt ccc ggt gct cca      384
 Arg Arg Gly Arg Glu Pro Glu Gly Ala Thr Gly Leu Pro Gly Ala Pro
         115                 120                 125

 gcg gcc gag ggg gag ccc gag gag gag gac ggg ggc gcg gct ggg cag      432
 Ala Ala Glu Gly Glu Pro Glu Glu Glu Asp Gly Gly Ala Ala Gly Gln
     130                 135                 140

 cgg aga gac ggc cgg ccg ggg agt agc cac aac ggc agc ggg gac ggg      480
 Arg Arg Asp Gly Arg Pro Gly Ser Ser His Asn Gly Ser Gly Asp Gly
 145                 150                 155                 160

 ggc gct gcc gcc ccg agc gcc cga ccc cgg gac ttc ctg tac gtg ggg      528
 Gly Ala Ala Ala Pro Ser Ala Arg Pro Arg Asp Phe Leu Tyr Val Gly
                 165                 170                 175

 gtg atg acc gcg cag aag tac ctg ggc agc cgc gcg ctg gcc gcg cag      576
 Val Met Thr Ala Gln Lys Tyr Leu Gly Ser Arg Ala Leu Ala Ala Gln
             180                 185                 190

 cgg acc tgg gcg cgt ttc atc ccg ggc cgc gtg gag ttc ttt tcc agc      624
 Arg Thr Trp Ala Arg Phe Ile Pro Gly Arg Val Glu Phe Phe Ser Ser
         195                 200                 205

 cag cag ccc ccc aac gcc ggc cag ccc ccg cca ccc ctg cct gtc atc      672
 Gln Gln Pro Pro Asn Ala Gly Gln Pro Pro Pro Pro Leu Pro Val Ile
     210                 215                 220

 gcg cta ccg ggt gtg gac gac tcc tat cct ccc cag aaa aag tcc ttc      720
 Ala Leu Pro Gly Val Asp Asp Ser Tyr Pro Pro Gln Lys Lys Ser Phe
 225                 230                 235                 240

 atg atg atc aag tac atg cac gac cac tac ctg gac aag tat gag tgg      768
 Met Met Ile Lys Tyr Met His Asp His Tyr Leu Asp Lys Tyr Glu Trp
                 245                 250                 255

 ttc atg cgc gcc gac gac gat gtc tac atc aaa ggt gat aaa tta gaa      816
 Phe Met Arg Ala Asp Asp Asp Val Tyr Ile Lys Gly Asp Lys Leu Glu
             260                 265                 270

 gag ttt ctt aga tcg cta aac agc agt aag cct ctc tac ctg gga cag      864
 Glu Phe Leu Arg Ser Leu Asn Ser Ser Lys Pro Leu Tyr Leu Gly Gln
         275                 280                 285

 act ggc ctg ggg aat att gaa gag ctt gga aag ctg gga ctg gag cct      912
 Thr Gly Leu Gly Asn Ile Glu Glu Leu Gly Lys Leu Gly Leu Glu Pro
     290                 295                 300

 ggg gaa aac ttc tgt atg gga gga cct ggc atg atc ttt agc cga gaa      960
 Gly Glu Asn Phe Cys Met Gly Gly Pro Gly Met Ile Phe Ser Arg Glu
 305                 310                 315                 320

 gtt ctc agg agg atg gtg cca cat att ggt gaa tgc ctt aga gaa atg     1008
 Val Leu Arg Arg Met Val Pro His Ile Gly Glu Cys Leu Arg Glu Met
                 325                 330                 335

 tac acg act cat gag gat gtg gaa gta gga aga tgc gtt cgc cgt ttt     1056
 Tyr Thr Thr His Glu Asp Val Glu Val Gly Arg Cys Val Arg Arg Phe
             340                 345                 350

 ggt ggg act cag tgt gtc tgg tct tac gag gaa cct atc ttt ccc ctt     1104
 Gly Gly Thr Gln Cys Val Trp Ser Tyr Glu Glu Pro Ile Phe Pro Leu
         355                 360                 365

 aag act ttc aat tga                                                 1119
 Lys Thr Phe Asn 
     370





      <210> 688
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 688
  atg gcc aag gtc tca gtc tct gtc ctg ctg att gct gga gca ggt gtg      48
  Met Ala Lys Val Ser Val Ser Val Leu Leu Ile Ala Gly Ala Gly Val
    1               5                  10                  15

 gtg gcc cat gtc cga gga cgg ctg tgt cct gga gag ctg ctt agg aca       96
 Val Ala His Val Arg Gly Arg Leu Cys Pro Gly Glu Leu Leu Arg Thr
              20                  25                  30

 cat tcc cag aca gga ctg aag caa ttc acg ctg cta cag tcg ctg gtc      144
 His Ser Gln Thr Gly Leu Lys Gln Phe Thr Leu Leu Gln Ser Leu Val
          35                  40                  45

 atg cga agg gcc acc cca cag cac ttc act ggc gac tac tgc gaa cac      192
 Met Arg Arg Ala Thr Pro Gln His Phe Thr Gly Asp Tyr Cys Glu His
      50                  55                  60

 tgg cgg ccc cct cac ccc gtg ggc agc ctg tcg gca gct gct tac ctc      240
 Trp Arg Pro Pro His Pro Val Gly Ser Leu Ser Ala Ala Ala Tyr Leu
  65                  70                  75                  80

 ctt ccc ccc gac ttt gga gag ttc atc cag ctt tta aaa aca gga atg      288
 Leu Pro Pro Asp Phe Gly Glu Phe Ile Gln Leu Leu Lys Thr Gly Met
                  85                  90                  95

 gct tgt ccc ctg aca tct aca caa tac cgg cac aag gtt ccc att aaa      336
 Ala Cys Pro Leu Thr Ser Thr Gln Tyr Arg His Lys Val Pro Ile Lys
             100                 105                 110

 cta gca agt cgg aaa act tgg aag gaa gga gaa gaa aca tca gga ctt      384
 Leu Ala Ser Arg Lys Thr Trp Lys Glu Gly Glu Glu Thr Ser Gly Leu
         115                 120                 125

 acg agc cgc tga                                                      396
 Thr Ser Arg 
     130





      <210> 689
      <211> 279
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(279)

      <400> 689
  atg tca gga gat ctg aag atg gta acc agg tta cct ctg tat ctt ttc      48
  Met Ser Gly Asp Leu Lys Met Val Thr Arg Leu Pro Leu Tyr Leu Phe
    1               5                  10                  15

 att ggc tat ctc cca gat ata act ctg aaa gct ttt aac aag atc ttc       96
 Ile Gly Tyr Leu Pro Asp Ile Thr Leu Lys Ala Phe Asn Lys Ile Phe
              20                  25                  30

 tct tct ctc ttt ctc atg tgt ctt tca gat acc gtg ctg ctt tgg aca      144
 Ser Ser Leu Phe Leu Met Cys Leu Ser Asp Thr Val Leu Leu Trp Thr
          35                  40                  45

 act caa cct gcc ctg gac agt gtg ggg gcc cag act cta gtt gat tca      192
 Thr Gln Pro Ala Leu Asp Ser Val Gly Ala Gln Thr Leu Val Asp Ser
      50                  55                  60

 ttt ttg cct ttg cca tgg cac caa gca cag aac ctt tca caa aat agg      240
 Phe Leu Pro Leu Pro Trp His Gln Ala Gln Asn Leu Ser Gln Asn Arg
  65                  70                  75                  80

 tat gca aaa gag ttc aat gaa ttt cat ggc aat ttc tga                  279
 Tyr Ala Lys Glu Phe Asn Glu Phe His Gly Asn Phe 
                  85                  90





      <210> 690
      <211> 330
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(330)

      <400> 690
  atg aga aac ttg gtt agt ggc tct ctt ggc atg ttc gta gcc ctg tgg      48
  Met Arg Asn Leu Val Ser Gly Ser Leu Gly Met Phe Val Ala Leu Trp
    1               5                  10                  15

 ttg aag tgg ctg aaa cct gcg ttg agc ctc agt cca agc agc tgg ggc       96
 Leu Lys Trp Leu Lys Pro Ala Leu Ser Leu Ser Pro Ser Ser Trp Gly
              20                  25                  30

 cac acc agt ttg caa aag cgg atg tgg cag ttt cca ccg cag cag cag      144
 His Thr Ser Leu Gln Lys Arg Met Trp Gln Phe Pro Pro Gln Gln Gln
          35                  40                  45

 cct gct ggc gcc tca tca gat tct cct ttg gag gaa gta tct tct tcc      192
 Pro Ala Gly Ala Ser Ser Asp Ser Pro Leu Glu Glu Val Ser Ser Ser
      50                  55                  60

 ctt cat tct cgc tgt cta cca cca gct gct gcg ctt gtg gat gac tgc      240
 Leu His Ser Arg Cys Leu Pro Pro Ala Ala Ala Leu Val Asp Asp Cys
  65                  70                  75                  80

 agg aac acc ggg tac ttg cca caa gta tct ctc cag att cat cag cct      288
 Arg Asn Thr Gly Tyr Leu Pro Gln Val Ser Leu Gln Ile His Gln Pro
                  85                  90                  95

 ttc acc tgt gac aag ctc agt caa gaa gtg gct cct aag taa              330
 Phe Thr Cys Asp Lys Leu Ser Gln Glu Val Ala Pro Lys 
             100                 105





      <210> 691
      <211> 1332
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1332)

      <400> 691
  atg tgc cat agg gcc act gtg aaa agc agg ttt gcc cta gtg tgc cat      48
  Met Cys His Arg Ala Thr Val Lys Ser Arg Phe Ala Leu Val Cys His
    1               5                  10                  15

 gcg tgg att gct aac tcc aag agg atg aat gtc tgc tgc ctc ctt acc       96
 Ala Trp Ile Ala Asn Ser Lys Arg Met Asn Val Cys Cys Leu Leu Thr
              20                  25                  30

 ctg ttt ctg atc tgc cca ctg ctc tct cgc agg ccc gtc atc ctg agt      144
 Leu Phe Leu Ile Cys Pro Leu Leu Ser Arg Arg Pro Val Ile Leu Ser
          35                  40                  45

 ccc acc atg gag gag ggc cat ggg ctg gac ctc act tac atc acg gag      192
 Pro Thr Met Glu Glu Gly His Gly Leu Asp Leu Thr Tyr Ile Thr Glu
      50                  55                  60

 cgc atc atc gct gtg tcc ttc cct gcc ggc tgc tct gag gag tcc tac      240
 Arg Ile Ile Ala Val Ser Phe Pro Ala Gly Cys Ser Glu Glu Ser Tyr
  65                  70                  75                  80

 ctg cac aac cta cag gag gtc acg cgc atg ctc aag tcc aag cac ggg      288
 Leu His Asn Leu Gln Glu Val Thr Arg Met Leu Lys Ser Lys His Gly
                  85                  90                  95

 gac aac tac ctg atc atg gat gtg ggc tgg cca gag ctc cac gca ccg      336
 Asp Asn Tyr Leu Ile Met Asp Val Gly Trp Pro Glu Leu His Ala Pro
             100                 105                 110

 ccc ctg gat aag atg tgt acc ata tgc aag gcg cag gag tcc tgg ctg      384
 Pro Leu Asp Lys Met Cys Thr Ile Cys Lys Ala Gln Glu Ser Trp Leu
         115                 120                 125

 aac agc aac ctc cag cat gtg gtc gtc att cac tgc agg cac caa gga      432
 Asn Ser Asn Leu Gln His Val Val Val Ile His Cys Arg His Gln Gly
     130                 135                 140

 gtg aaa ttt gac ttt ctg aat gtt ttc tct gga aac caa ctg agg agt      480
 Val Lys Phe Asp Phe Leu Asn Val Phe Ser Gly Asn Gln Leu Arg Ser
 145                 150                 155                 160

 tgg tgc ctg cca ggg agg aaa cca acc ccc aac gcc gac cag gcc ctt      528
 Trp Cys Leu Pro Gly Arg Lys Pro Thr Pro Asn Ala Asp Gln Ala Leu
                 165                 170                 175

 gac agg ttt gca atg aag aag ttt tat gat gac aaa gtt tca gct tta      576
 Asp Arg Phe Ala Met Lys Lys Phe Tyr Asp Asp Lys Val Ser Ala Leu
             180                 185                 190

 atg cag cct tcc caa aaa cgg tat gtt cag ttc ctc agt ggg ctc ctg      624
 Met Gln Pro Ser Gln Lys Arg Tyr Val Gln Phe Leu Ser Gly Leu Leu
         195                 200                 205

 tcc gga tcg gtg aaa atg aat gcc tct ccc ctg ttc ctg cat ttt gtc      672
 Ser Gly Ser Val Lys Met Asn Ala Ser Pro Leu Phe Leu His Phe Val
     210                 215                 220

 atc ctc cac ggc acc ccc aac ttc gac aca ggt gga gtg tgc cgg ccc      720
 Ile Leu His Gly Thr Pro Asn Phe Asp Thr Gly Gly Val Cys Arg Pro
 225                 230                 235                 240

 ttt ctg aag ctc tac caa gcc atg cag cct gtg tac acc tcc ggg atc      768
 Phe Leu Lys Leu Tyr Gln Ala Met Gln Pro Val Tyr Thr Ser Gly Ile
                 245                 250                 255

 tac aac gtt ggc cca gaa aac ccc agc agg atc tgc atc gtc atc gag      816
 Tyr Asn Val Gly Pro Glu Asn Pro Ser Arg Ile Cys Ile Val Ile Glu
             260                 265                 270

 ccg gcc cag ctt ctg aag gga gat gtc atg gtg aaa tgc tac cac aag      864
 Pro Ala Gln Leu Leu Lys Gly Asp Val Met Val Lys Cys Tyr His Lys
         275                 280                 285

 aaa tac cgc tcg gcc acc cgt gac gtc att ttc cgc ctg cag ttt cac      912
 Lys Tyr Arg Ser Ala Thr Arg Asp Val Ile Phe Arg Leu Gln Phe His
     290                 295                 300

 act ggg gct gtg cag ggc tac ggg ctg gtg ttt ggg aag gag gat ctg      960
 Thr Gly Ala Val Gln Gly Tyr Gly Leu Val Phe Gly Lys Glu Asp Leu
 305                 310                 315                 320

 gac aat gcc agc aaa gat gac cgt ttt cct gac tat ggg aag gtt gaa     1008
 Asp Asn Ala Ser Lys Asp Asp Arg Phe Pro Asp Tyr Gly Lys Val Glu
                 325                 330                 335

 tta gtc ttc tct gcc acg cct gag aag att caa ggg tcc gaa cac ttg     1056
 Leu Val Phe Ser Ala Thr Pro Glu Lys Ile Gln Gly Ser Glu His Leu
             340                 345                 350

 tac aac gac cac ggt gtg att gtg gac tac aac aca aca gac cca ctg     1104
 Tyr Asn Asp His Gly Val Ile Val Asp Tyr Asn Thr Thr Asp Pro Leu
         355                 360                 365

 ata cgc tgg gac tcg tac gag aac ctc agt gca gat gga gaa ggc ctt     1152
 Ile Arg Trp Asp Ser Tyr Glu Asn Leu Ser Ala Asp Gly Glu Gly Leu
     370                 375                 380

 gtg gga tgg aat ttc aac tca agg aat tgt tgc aac cca aat aca cct     1200
 Val Gly Trp Asn Phe Asn Ser Arg Asn Cys Cys Asn Pro Asn Thr Pro
 385                 390                 395                 400

 aga cca gag gtg gag acc cac aga tgg aat gtt gat gcc tcg atg ata     1248
 Arg Pro Glu Val Glu Thr His Arg Trp Asn Val Asp Ala Ser Met Ile
                 405                 410                 415

 tct gaa gcc cat gag cac ccc cag gga ggt gga gtg aca ggg gag gac     1296
 Ser Glu Ala His Glu His Pro Gln Gly Gly Gly Val Thr Gly Glu Asp
             420                 425                 430

 tca gag cga gct cag gac tgg tat ccg gat gct tag                     1332
 Ser Glu Arg Ala Gln Asp Trp Tyr Pro Asp Ala 
         435                 440





      <210> 692
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 692
  atg ggg tcc cca ggg tgt tgg ctg ctc ccc ctc tcc ctg tgt gct gag      48
  Met Gly Ser Pro Gly Cys Trp Leu Leu Pro Leu Ser Leu Cys Ala Glu
    1               5                  10                  15

 ctc cct gtg tgc ggg cct agc atc cag ctt gca gcg tgg acc aag tgg       96
 Leu Pro Val Cys Gly Pro Ser Ile Gln Leu Ala Ala Trp Thr Lys Trp
              20                  25                  30

 ggt cct ggt gcc gtg gga gcc ctg att gct gga gga gcc cag ctg ggg      144
 Gly Pro Gly Ala Val Gly Ala Leu Ile Ala Gly Gly Ala Gln Leu Gly
          35                  40                  45

 cca caa cta ggg cag cga gtg cag ggt atg gcg ccc cag gtg ggg tca      192
 Pro Gln Leu Gly Gln Arg Val Gln Gly Met Ala Pro Gln Val Gly Ser
      50                  55                  60

 ggg gga gtc aga tgg agg agc ggt cgg ccc ctt tgg ttg agt ttt gaa      240
 Gly Gly Val Arg Trp Arg Ser Gly Arg Pro Leu Trp Leu Ser Phe Glu
  65                  70                  75                  80

 gga ata caa gta gat ggt aga tga                                      264
 Gly Ile Gln Val Asp Gly Arg 
                  85





      <210> 693
      <211> 1032
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1032)

      <400> 693
  atg tgg cca ctg aca gcc ctt ctg ctc ctg gtt cca agc agt ggg caa      48
  Met Trp Pro Leu Thr Ala Leu Leu Leu Leu Val Pro Ser Ser Gly Gln
    1               5                  10                  15

 gct gct act ctg gag aag ccc ata ttg tct cta cat cca cct tgg acc       96
 Ala Ala Thr Leu Glu Lys Pro Ile Leu Ser Leu His Pro Pro Trp Thr
              20                  25                  30

 acc atc ttc aaa ggg gag cgg gta act ttg aag tgt gat gga tac cac      144
 Thr Ile Phe Lys Gly Glu Arg Val Thr Leu Lys Cys Asp Gly Tyr His
          35                  40                  45

 cca ctg ctc ctg gag ctc cag ccc atc agc act ctc tgg tat ttg ggc      192
 Pro Leu Leu Leu Glu Leu Gln Pro Ile Ser Thr Leu Trp Tyr Leu Gly
      50                  55                  60

 cac cta ctt ctg ccc tct cac aag aag agc att gag gtg cag aca cca      240
 His Leu Leu Leu Pro Ser His Lys Lys Ser Ile Glu Val Gln Thr Pro
  65                  70                  75                  80

 ggg gtg tat cga tgc cag aca cgg gga gca ccc gtc agt gac ccc atc      288
 Gly Val Tyr Arg Cys Gln Thr Arg Gly Ala Pro Val Ser Asp Pro Ile
                  85                  90                  95

 cac ctc tct gta tcc aat gat tgg ctg att ctg caa gtg ccc tat gcg      336
 His Leu Ser Val Ser Asn Asp Trp Leu Ile Leu Gln Val Pro Tyr Ala
             100                 105                 110

 cca gtg ttc gag ggt gag ccg cta gtc ctg cgc tgc cgc ggc tgg tac      384
 Pro Val Phe Glu Gly Glu Pro Leu Val Leu Arg Cys Arg Gly Trp Tyr
         115                 120                 125

 gac aag gtg gtc tac aag ctt cac tac tac cac gac ggc cag gcc gtg      432
 Asp Lys Val Val Tyr Lys Leu His Tyr Tyr His Asp Gly Gln Ala Val
     130                 135                 140

 cgc tac ttc cac tcc agc gcc aac tac act gtg tta cag gcg cgt gcc      480
 Arg Tyr Phe His Ser Ser Ala Asn Tyr Thr Val Leu Gln Ala Arg Ala
 145                 150                 155                 160

 agc gac agc ggg cgc tac cag tgc tcg ggc acc atg cgc atc ccg gtg      528
 Ser Asp Ser Gly Arg Tyr Gln Cys Ser Gly Thr Met Arg Ile Pro Val
                 165                 170                 175

 gag agc gcg ccc atg ttc tcc gct aag gtg gct gtg aca gtg caa gag      576
 Glu Ser Ala Pro Met Phe Ser Ala Lys Val Ala Val Thr Val Gln Glu
             180                 185                 190

 ctg ttc cgg gcg ccg gtg ctg agg gtg atg ggt ccg cgg gag gcc cgc      624
 Leu Phe Arg Ala Pro Val Leu Arg Val Met Gly Pro Arg Glu Ala Arg
         195                 200                 205

 ggc gcg gcg ctg ggt ggg gtg gtg ctg cgc tgc gac acg cgc ctg cac      672
 Gly Ala Ala Leu Gly Gly Val Val Leu Arg Cys Asp Thr Arg Leu His
     210                 215                 220

 ccg cag aag cgc gac acg ccg ctg cag ttc gcg ttt tac aag tac agc      720
 Pro Gln Lys Arg Asp Thr Pro Leu Gln Phe Ala Phe Tyr Lys Tyr Ser
 225                 230                 235                 240

 cgc gcg gtg cgc cgc ttc gac tgg ggc gcc gag tac aca gtc ccg gag      768
 Arg Ala Val Arg Arg Phe Asp Trp Gly Ala Glu Tyr Thr Val Pro Glu
                 245                 250                 255

 ccc gag gtc gag gag ctc gaa tcg tac tgg tgc gag gcg gct acc gcc      816
 Pro Glu Val Glu Glu Leu Glu Ser Tyr Trp Cys Glu Ala Ala Thr Ala
             260                 265                 270

 acc cgc agt gtc cgg aaa cgc agt ccg tgg ctg cag ctc ccg ggg ccg      864
 Thr Arg Ser Val Arg Lys Arg Ser Pro Trp Leu Gln Leu Pro Gly Pro
         275                 280                 285

 ggt gag tgc ctg cac acc ctc ccg gac gcc gac cct ggc ggt cag ccc      912
 Gly Glu Cys Leu His Thr Leu Pro Asp Ala Asp Pro Gly Gly Gln Pro
     290                 295                 300

 tgc ttc cgc ctc tcg gca ccc acg aat cac ccg cga gaa ttg gaa gag      960
 Cys Phe Arg Leu Ser Ala Pro Thr Asn His Pro Arg Glu Leu Glu Glu
 305                 310                 315                 320

 aat gct tgc ggt tac aaa ctg ctg tgt gag gtt gaa atc gtc agc cac     1008
 Asn Ala Cys Gly Tyr Lys Leu Leu Cys Glu Val Glu Ile Val Ser His
                 325                 330                 335

 tac act tcg tgg gcg ctc ctt taa                                     1032
 Tyr Thr Ser Trp Ala Leu Leu 
             340





      <210> 694
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 694
  atg gcc atg gtg gtg ctg ggt ctg tcc ccc att ccg tgg cag gca ctt      48
  Met Ala Met Val Val Leu Gly Leu Ser Pro Ile Pro Trp Gln Ala Leu
    1               5                  10                  15

 gtc tct tgc ccc ctt cgc tgc ctg ttc ctc tct gag cag gat cca gtc       96
 Val Ser Cys Pro Leu Arg Cys Leu Phe Leu Ser Glu Gln Asp Pro Val
              20                  25                  30

 cag ggg acc aca ttg cat gtg gtc aca cca gcc cag cac ccc ctg ccc      144
 Gln Gly Thr Thr Leu His Val Val Thr Pro Ala Gln His Pro Leu Pro
          35                  40                  45

 ggg gac agc tcc cgc ctt tcc tta ttt cac aca cag ttt ggt ggt ctc      192
 Gly Asp Ser Ser Arg Leu Ser Leu Phe His Thr Gln Phe Gly Gly Leu
      50                  55                  60

 cat gta aca cgg gat ctt cat agc tcc cag aag gaa agc cat gca gcg      240
 His Val Thr Arg Asp Leu His Ser Ser Gln Lys Glu Ser His Ala Ala
  65                  70                  75                  80

 gca gcg tgt gtt tgg aga cat ttt cct ggc ctt tac atc aca gcc agg      288
 Ala Ala Cys Val Trp Arg His Phe Pro Gly Leu Tyr Ile Thr Ala Arg
                  85                  90                  95

 cgt gac tca caa gca gat gac tca gtg gca aaa gtg acc aat gag cta      336
 Arg Asp Ser Gln Ala Asp Asp Ser Val Ala Lys Val Thr Asn Glu Leu
             100                 105                 110

 ggg gaa aat gag aat ctg gga aca gtg gaa caa atg gaa aat gcc aga      384
 Gly Glu Asn Glu Asn Leu Gly Thr Val Glu Gln Met Glu Asn Ala Arg
         115                 120                 125

 gtc agt gcg tgt gga cgg ctg ctg tga                                  411
 Val Ser Ala Cys Gly Arg Leu Leu 
     130                 135





      <210> 695
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 695
  atg aca agt ttg cgt cca gcc atc tcc gcc ctg ctg gca ggc tgt gcc      48
  Met Thr Ser Leu Arg Pro Ala Ile Ser Ala Leu Leu Ala Gly Cys Ala
    1               5                  10                  15

 tct ttg gcg gtg gcc gag cgc gaa gtt gct ctg tgg ctc tgg act ggg       96
 Ser Leu Ala Val Ala Glu Arg Glu Val Ala Leu Trp Leu Trp Thr Gly
              20                  25                  30

 atc gtg ttt gtt caa tgg aca aag gct gag aat ccc gag gcc gac tgc      144
 Ile Val Phe Val Gln Trp Thr Lys Ala Glu Asn Pro Glu Ala Asp Cys
          35                  40                  45

 cca gtg gct gct gca cct caa gac ccc gag ggc tct cag agc cag cct      192
 Pro Val Ala Ala Ala Pro Gln Asp Pro Glu Gly Ser Gln Ser Gln Pro
      50                  55                  60

 gaa act acc cac ggg tgc tgt gga ccc ctt gat cat ggc ggg atg gaa      240
 Glu Thr Thr His Gly Cys Cys Gly Pro Leu Asp His Gly Gly Met Glu
  65                  70                  75                  80

 atg ggc tgt gcc ctc agc cgg gac tca gga ctg cag cat gtc tgg gca      288
 Met Gly Cys Ala Leu Ser Arg Asp Ser Gly Leu Gln His Val Trp Ala
                  85                  90                  95

 gca gcc tgg aag ctg gcc agc ctc ggc gcc ctt ggg gac agc cct tga      336
 Ala Ala Trp Lys Leu Ala Ser Leu Gly Ala Leu Gly Asp Ser Pro 
             100                 105                 110





      <210> 696
      <211> 915
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(915)

      <400> 696
  atg ttc tcg gtc ctc tcg tac ggg cgg ctg gtg gcc cgc gcc gtg ctc      48
  Met Phe Ser Val Leu Ser Tyr Gly Arg Leu Val Ala Arg Ala Val Leu
    1               5                  10                  15

 ggc ggc ctc tcg cag acc gac ccc agg gcc ggc ggc ggc ggc ggc ggc       96
 Gly Gly Leu Ser Gln Thr Asp Pro Arg Ala Gly Gly Gly Gly Gly Gly
              20                  25                  30

 gac tac gga ctg gtg acg gcc ggc tgc ggc ttc ggg aag gac ttc cgt      144
 Asp Tyr Gly Leu Val Thr Ala Gly Cys Gly Phe Gly Lys Asp Phe Arg
          35                  40                  45

 aag ggc ctc ctc aag aag ggc gcg tgc tac ggg gac gac gcg tgc ttc      192
 Lys Gly Leu Leu Lys Lys Gly Ala Cys Tyr Gly Asp Asp Ala Cys Phe
      50                  55                  60

 gtg gcc cgg cac cgt tcc gcg gac gtg ctc ggg gtt gca gat ggt gta      240
 Val Ala Arg His Arg Ser Ala Asp Val Leu Gly Val Ala Asp Gly Val
  65                  70                  75                  80

 gga ggc tgg aga gac tat gga gtt gat cca tct caa ttc tca ggg act      288
 Gly Gly Trp Arg Asp Tyr Gly Val Asp Pro Ser Gln Phe Ser Gly Thr
                  85                  90                  95

 tta atg cgg acg tgt gaa cgt tta gta aaa gaa gga cgg ttc gta cct      336
 Leu Met Arg Thr Cys Glu Arg Leu Val Lys Glu Gly Arg Phe Val Pro
             100                 105                 110

 agt aat ccc att gga att ctc acc aca agc tac tgt gag ttg ctg caa      384
 Ser Asn Pro Ile Gly Ile Leu Thr Thr Ser Tyr Cys Glu Leu Leu Gln
         115                 120                 125

 aat aaa gtc cct ttg ctc ggt agc agc acc gcc tgc att gtg gtg ctg      432
 Asn Lys Val Pro Leu Leu Gly Ser Ser Thr Ala Cys Ile Val Val Leu
     130                 135                 140

 gac aga acc agc cac cgc tta cac aca gca aac ctg ggc gat tca ggc      480
 Asp Arg Thr Ser His Arg Leu His Thr Ala Asn Leu Gly Asp Ser Gly
 145                 150                 155                 160

 ttc ctg gtt gtc agg ggt ggt gaa gtc gtg cac cga tca gat gag cag      528
 Phe Leu Val Val Arg Gly Gly Glu Val Val His Arg Ser Asp Glu Gln
                 165                 170                 175

 cag cat tac ttc aac act cca ttc cag ctc tca atc gct ccc cct gaa      576
 Gln His Tyr Phe Asn Thr Pro Phe Gln Leu Ser Ile Ala Pro Pro Glu
             180                 185                 190

 gcc gag gga gtc gtc ttg agc gac agt ccg gat gct gct gat agc acg      624
 Ala Glu Gly Val Val Leu Ser Asp Ser Pro Asp Ala Ala Asp Ser Thr
         195                 200                 205

 tct ttc gat gtc cag cta gga gac att atc ctg acg gca aca gat gga      672
 Ser Phe Asp Val Gln Leu Gly Asp Ile Ile Leu Thr Ala Thr Asp Gly
     210                 215                 220

 ctc ttt gac aac atg cct gat tat atg att ctt cag gag cta aaa aag      720
 Leu Phe Asp Asn Met Pro Asp Tyr Met Ile Leu Gln Glu Leu Lys Lys
 225                 230                 235                 240

 tta aag aat tca aat tat gag agt ata caa cag act gcc aga agc att      768
 Leu Lys Asn Ser Asn Tyr Glu Ser Ile Gln Gln Thr Ala Arg Ser Ile
                 245                 250                 255

 gct gag caa gct cat gag ctg gcc tat gac cca aat tat atg tca cct      816
 Ala Glu Gln Ala His Glu Leu Ala Tyr Asp Pro Asn Tyr Met Ser Pro
             260                 265                 270

 ttt gca cag ttt gca tgt gac aat gga ttg aat gtg aga ggt gga aag      864
 Phe Ala Gln Phe Ala Cys Asp Asn Gly Leu Asn Val Arg Gly Gly Lys
         275                 280                 285

 cca gat gac atc acc gtc ctt ctt tca ata gtg gct gag tat aca gac      912
 Pro Asp Asp Ile Thr Val Leu Leu Ser Ile Val Ala Glu Tyr Thr Asp
     290                 295                 300

 tag                                                                  915
 






      <210> 697
      <211> 654
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(654)

      <400> 697
  atg act gga gtg ggc tgg agt ttg gta ttc ctc ttc tcc cca gtg gaa      48
  Met Thr Gly Val Gly Trp Ser Leu Val Phe Leu Phe Ser Pro Val Glu
    1               5                  10                  15

 agc ttg aag aag ctg gag ctg tat ttt ctt ctt act cca gaa aat gag       96
 Ser Leu Lys Lys Leu Glu Leu Tyr Phe Leu Leu Thr Pro Glu Asn Glu
              20                  25                  30

 gct gtg gga aaa agt tgg att gtt aaa aga agt tat gaa gat ttt cgg      144
 Ala Val Gly Lys Ser Trp Ile Val Lys Arg Ser Tyr Glu Asp Phe Arg
          35                  40                  45

 gta ctt gat aaa cat ctt cat ctg tgt att tat gac cga aga ttt tcc      192
 Val Leu Asp Lys His Leu His Leu Cys Ile Tyr Asp Arg Arg Phe Ser
      50                  55                  60

 cag ctc tca gaa ctt ccc cgt tct gac acc ctg aag gac agt cca gag      240
 Gln Leu Ser Glu Leu Pro Arg Ser Asp Thr Leu Lys Asp Ser Pro Glu
  65                  70                  75                  80

 att gat aat aag gga aat cac ctt ttg gtt cat gag gag tca tcc atc      288
 Ile Asp Asn Lys Gly Asn His Leu Leu Val His Glu Glu Ser Ser Ile
                  85                  90                  95

 aac act cct gct gtc ggt gct gcc cat gtt atc aag agg tac act gct      336
 Asn Thr Pro Ala Val Gly Ala Ala His Val Ile Lys Arg Tyr Thr Ala
             100                 105                 110

 cgg gcc cct gac gaa ctg acc tta gag gtg gga gac att gtt tct gtt      384
 Arg Ala Pro Asp Glu Leu Thr Leu Glu Val Gly Asp Ile Val Ser Val
         115                 120                 125

 att gac atg ccc ccg aaa gtg tta agc aca tgg tgg aga ggc aag cac      432
 Ile Asp Met Pro Pro Lys Val Leu Ser Thr Trp Trp Arg Gly Lys His
     130                 135                 140

 gga ttc cag gtg gga ctc ttc cct gga cac tgt gtt gag tta att aac      480
 Gly Phe Gln Val Gly Leu Phe Pro Gly His Cys Val Glu Leu Ile Asn
 145                 150                 155                 160

 caa aaa gtt ccc cag tca gtg acc aac tca gtg cca aaa cca gga ttc      528
 Gln Lys Val Pro Gln Ser Val Thr Asn Ser Val Pro Lys Pro Gly Phe
                 165                 170                 175

 aaa gct cag ggg cag cac gca gca gaa gat ttt gga atg gtg cat gat      576
 Lys Ala Gln Gly Gln His Ala Ala Glu Asp Phe Gly Met Val His Asp
             180                 185                 190

 gaa tcc tcc ctg gat atc tca tct ctt gcc agt tac tgt tat ggg acc      624
 Glu Ser Ser Leu Asp Ile Ser Ser Leu Ala Ser Tyr Cys Tyr Gly Thr
         195                 200                 205

 ttg gca aat tgc ttc atc tct ctg cct tag                              654
 Leu Ala Asn Cys Phe Ile Ser Leu Pro 
     210                 215





      <210> 698
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 698
  atg cag ctt gcc aga tcc tcc ctt gga ctc ttc ttg ata aac tgc tct      48
  Met Gln Leu Ala Arg Ser Ser Leu Gly Leu Phe Leu Ile Asn Cys Ser
    1               5                  10                  15

 gtc tct aag aca act ctg ccc gtg ctg acc tta ttc aca aag gac cca       96
 Val Ser Lys Thr Thr Leu Pro Val Leu Thr Leu Phe Thr Lys Asp Pro
              20                  25                  30

 cgc ccc ctt tgt ggt gaa gcc aag gaa gta ctc aag cct tat agt aac      144
 Arg Pro Leu Cys Gly Glu Ala Lys Glu Val Leu Lys Pro Tyr Ser Asn
          35                  40                  45

 agg ttt att tta cag gaa gtg aac gtc aca ctt cca gaa aac tct gcc      192
 Arg Phe Ile Leu Gln Glu Val Asn Val Thr Leu Pro Glu Asn Ser Ala
      50                  55                  60

 tgg tat gaa agg tat aaa ttt gac att cct gtc ttt cac ttg tgt ggc      240
 Trp Tyr Glu Arg Tyr Lys Phe Asp Ile Pro Val Phe His Leu Cys Gly
  65                  70                  75                  80

 cag ttt ctg atg atg cat caa gaa aac acc tca aaa ctt gac aaa cag      288
 Gln Phe Leu Met Met His Gln Glu Asn Thr Ser Lys Leu Asp Lys Gln
                  85                  90                  95

 ctc ctg aaa ctt gag cag caa agt acc gga ggc tga                      324
 Leu Leu Lys Leu Glu Gln Gln Ser Thr Gly Gly 
             100                 105





      <210> 699
      <211> 981
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(981)

      <400> 699
  atg cct agt ggg cct att gga ttt tgg agg caa cac att tct cat ttg      48
  Met Pro Ser Gly Pro Ile Gly Phe Trp Arg Gln His Ile Ser His Leu
    1               5                  10                  15

 ggt atg tta ctc tgg tcc act tat caa gtg acc caa aag gct acg agt       96
 Gly Met Leu Leu Trp Ser Thr Tyr Gln Val Thr Gln Lys Ala Thr Ser
              20                  25                  30

 ttt gag tgg ggt cca gaa cag aag aat gct ctg caa cag gtc cag gct      144
 Phe Glu Trp Gly Pro Glu Gln Lys Asn Ala Leu Gln Gln Val Gln Ala
          35                  40                  45

 gct gtg caa gct tct ctg cca ttt ggg cca tat gac cca gca gat cca      192
 Ala Val Gln Ala Ser Leu Pro Phe Gly Pro Tyr Asp Pro Ala Asp Pro
      50                  55                  60

 atg aga cag ccc ttg gcc tgt tac tgg gct ttg gtg gaa act gaa cat      240
 Met Arg Gln Pro Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Glu His
  65                  70                  75                  80

 ttg act atg ggc cat caa gtc acc atg caa cct gaa ttg cct atc atg      288
 Leu Thr Met Gly His Gln Val Thr Met Gln Pro Glu Leu Pro Ile Met
                  85                  90                  95

 aac tgg ctg ctt tct gac cca tct agc cgt aag cct gca ctg acg gct      336
 Asn Trp Leu Leu Ser Asp Pro Ser Ser Arg Lys Pro Ala Leu Thr Ala
             100                 105                 110

 tca tgg gga gtt ctc tat gat cag ctg ata gag gaa gag aat act agg      384
 Ser Trp Gly Val Leu Tyr Asp Gln Leu Ile Glu Glu Glu Asn Thr Arg
         115                 120                 125

 gac tgg ttc aca ggt ggt tct gca cca tat gca ggc acc acc cca aag      432
 Asp Trp Phe Thr Gly Gly Ser Ala Pro Tyr Ala Gly Thr Thr Pro Lys
     130                 135                 140

 tgg aca gct gta gca cta cag ccc cgt tct agg aca tcc ctg aag gac      480
 Trp Thr Ala Val Ala Leu Gln Pro Arg Ser Arg Thr Ser Leu Lys Asp
 145                 150                 155                 160

 agc agt gaa ggg aaa tct tcc cag tgg gca gaa ctg cga gca gtg cac      528
 Ser Ser Glu Gly Lys Ser Ser Gln Trp Ala Glu Leu Arg Ala Val His
                 165                 170                 175

 ctg gtt gcg cac ttt gta tgg aag gag aaa tgg tca gat gtg cga tta      576
 Leu Val Ala His Phe Val Trp Lys Glu Lys Trp Ser Asp Val Arg Leu
             180                 185                 190

 tat act gat tca tgg gct gta gcc aat ggt ttg gct gga tgg tca ggg      624
 Tyr Thr Asp Ser Trp Ala Val Ala Asn Gly Leu Ala Gly Trp Ser Gly
         195                 200                 205

 tct tgg aag aag cat gat tgg aaa att ggt gac aag gaa att tgg gga      672
 Ser Trp Lys Lys His Asp Trp Lys Ile Gly Asp Lys Glu Ile Trp Gly
     210                 215                 220

 aga ggt atg tgg atg gac ctc tct gaa tgg tca aaa act ggg aag ata      720
 Arg Gly Met Trp Met Asp Leu Ser Glu Trp Ser Lys Thr Gly Lys Ile
 225                 230                 235                 240

 ttt gta tcc cac gtg agt gct cat caa cgg gtg acc tca gca gag gaa      768
 Phe Val Ser His Val Ser Ala His Gln Arg Val Thr Ser Ala Glu Glu
                 245                 250                 255

 gat ttt aat aat caa gtg gat aag atg acc tgt gct gtg gac acc act      816
 Asp Phe Asn Asn Gln Val Asp Lys Met Thr Cys Ala Val Asp Thr Thr
             260                 265                 270

 cag ctt ctt tcc cca gcc acc cct gcc atc gtc caa tgg gct cat gaa      864
 Gln Leu Leu Ser Pro Ala Thr Pro Ala Ile Val Gln Trp Ala His Glu
         275                 280                 285

 caa agt ggc cat ggt ggc agg gat gga ggt tac aca tgg gct cag caa      912
 Gln Ser Gly His Gly Gly Arg Asp Gly Gly Tyr Thr Trp Ala Gln Gln
     290                 295                 300

 cag gga ctt cca ctc acc aag gct gac ctg gct atg gcc act gct gag      960
 Gln Gly Leu Pro Leu Thr Lys Ala Asp Leu Ala Met Ala Thr Ala Glu
 305                 310                 315                 320

 tgc cca att tgc cag cag tag                                          981
 Cys Pro Ile Cys Gln Gln 
                 325





      <210> 700
      <211> 1476
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1476)

      <400> 700
  atg gct gcc ctg ctc ccg cct ctc acg gat ggc tgg acc tgg ctg tgc      48
  Met Ala Ala Leu Leu Pro Pro Leu Thr Asp Gly Trp Thr Trp Leu Cys
    1               5                  10                  15

 tgc ctg gga aga ggc cca gag agt ggg gac acc tgg gtt gca gtg cta       96
 Cys Leu Gly Arg Gly Pro Glu Ser Gly Asp Thr Trp Val Ala Val Leu
              20                  25                  30

 cac acg cag ggc cct gtc gat ggc agc ctt tac gcg aag gtg agg aag      144
 His Thr Gln Gly Pro Val Asp Gly Ser Leu Tyr Ala Lys Val Arg Lys
          35                  40                  45

 aaa agc tcc tcg gat cct ggc atc cca ggt ggc ccc cag gca atc ccg      192
 Lys Ser Ser Ser Asp Pro Gly Ile Pro Gly Gly Pro Gln Ala Ile Pro
      50                  55                  60

 gcc acc aac agc cca gac cac agt gac cac acc ttg tct gtc agc agt      240
 Ala Thr Asn Ser Pro Asp His Ser Asp His Thr Leu Ser Val Ser Ser
  65                  70                  75                  80

 gac tcc ggc cac tct aca gcc tct gcc agg acg gat aag acg gaa gag      288
 Asp Ser Gly His Ser Thr Ala Ser Ala Arg Thr Asp Lys Thr Glu Glu
                  85                  90                  95

 cgc ctg gcc cca gga acc agg agg ggc ctg agt gcc cag gag aag gca      336
 Arg Leu Ala Pro Gly Thr Arg Arg Gly Leu Ser Ala Gln Glu Lys Ala
             100                 105                 110

 gag ttg gac cag ctg ctc agt ggc ttt ggc ctg gaa gat cct gga agc      384
 Glu Leu Asp Gln Leu Leu Ser Gly Phe Gly Leu Glu Asp Pro Gly Ser
         115                 120                 125

 tcc ctc aag gaa atg act gat gct cga agc aag tac agt ggg acc cgc      432
 Ser Leu Lys Glu Met Thr Asp Ala Arg Ser Lys Tyr Ser Gly Thr Arg
     130                 135                 140

 cac gtg gtg cca gcc cag gtt cac gtg aat gga gac gct gct ctg aag      480
 His Val Val Pro Ala Gln Val His Val Asn Gly Asp Ala Ala Leu Lys
 145                 150                 155                 160

 gat cgg gag aca gac att ctg gat gac gag atg ccc cac cac gac ctg      528
 Asp Arg Glu Thr Asp Ile Leu Asp Asp Glu Met Pro His His Asp Leu
                 165                 170                 175

 cac agt gtg gac agc ctt ggg acc ctg tcc tcc tcg gaa ggg cct cag      576
 His Ser Val Asp Ser Leu Gly Thr Leu Ser Ser Ser Glu Gly Pro Gln
             180                 185                 190

 tcg gcc acc tgg agc agc cag aac tca ctc cta tct gac ggt ttt ggc      624
 Ser Ala Thr Trp Ser Ser Gln Asn Ser Leu Leu Ser Asp Gly Phe Gly
         195                 200                 205

 agc aac gtt ggt gaa gat ccg cag ggc acc ctc gtt ccg gac ctg ggc      672
 Ser Asn Val Gly Glu Asp Pro Gln Gly Thr Leu Val Pro Asp Leu Gly
     210                 215                 220

 ctt ggc atg gac ggc ccc tat gag cgg gag cgg act ttt ggg agt cga      720
 Leu Gly Met Asp Gly Pro Tyr Glu Arg Glu Arg Thr Phe Gly Ser Arg
 225                 230                 235                 240

 gag ccc aag cag ccc cag ccc ctg ctg aga aag ccc tca gtg tcc gcc      768
 Glu Pro Lys Gln Pro Gln Pro Leu Leu Arg Lys Pro Ser Val Ser Ala
                 245                 250                 255

 cag atg cag gcc tat ggg cag agc agc tac tcc aca cag acc tgg gtg      816
 Gln Met Gln Ala Tyr Gly Gln Ser Ser Tyr Ser Thr Gln Thr Trp Val
             260                 265                 270

 cgc cag cag cag atg gtt gta gct cac cag tat agc ttc gcc cca gat      864
 Arg Gln Gln Gln Met Val Val Ala His Gln Tyr Ser Phe Ala Pro Asp
         275                 280                 285

 ggg gag gcc cgg ctg gtg agc cgc tgc cct gca gac aat cct ggc ctc      912
 Gly Glu Ala Arg Leu Val Ser Arg Cys Pro Ala Asp Asn Pro Gly Leu
     290                 295                 300

 gtc cag gcc cag ccc aga gtg cca ctc acc ccc acc cga ggg acc agc      960
 Val Gln Ala Gln Pro Arg Val Pro Leu Thr Pro Thr Arg Gly Thr Ser
 305                 310                 315                 320

 agt agg gtg gct gtc cag agg ggt gta ggc agt ggg cca cat ccc cct     1008
 Ser Arg Val Ala Val Gln Arg Gly Val Gly Ser Gly Pro His Pro Pro
                 325                 330                 335

 gac aca cag cag ccc tct ccc agc aaa gcg ttc aaa ccc agg ttt cca     1056
 Asp Thr Gln Gln Pro Ser Pro Ser Lys Ala Phe Lys Pro Arg Phe Pro
             340                 345                 350

 gga gac cag gtt gtg aat gga gcc ggc cca gag ctg agc aca ggc ccc     1104
 Gly Asp Gln Val Val Asn Gly Ala Gly Pro Glu Leu Ser Thr Gly Pro
         355                 360                 365

 tcc cca ggc tcg ccc acc ctg gac atc gac cag tcc atc gag cag ctc     1152
 Ser Pro Gly Ser Pro Thr Leu Asp Ile Asp Gln Ser Ile Glu Gln Leu
     370                 375                 380

 aac agg ctg atc ctg gag ctg gat ccc acc ttc gag ccc atc cct acc     1200
 Asn Arg Leu Ile Leu Glu Leu Asp Pro Thr Phe Glu Pro Ile Pro Thr
 385                 390                 395                 400

 cac atg aac gcc ctc ggt agc cag gcc aat ggc tct gtg tct cca gac     1248
 His Met Asn Ala Leu Gly Ser Gln Ala Asn Gly Ser Val Ser Pro Asp
                 405                 410                 415

 agc gtg gga ggt ggg ctc cgg gca agc agc agg ctg cct gac aca gga     1296
 Ser Val Gly Gly Gly Leu Arg Ala Ser Ser Arg Leu Pro Asp Thr Gly
             420                 425                 430

 gag ggc ccc agc agg gcc acc ggg cgg caa ggt gtg ctg gcc cat gtc     1344
 Glu Gly Pro Ser Arg Ala Thr Gly Arg Gln Gly Val Leu Ala His Val
         435                 440                 445

 atc gtc cta agc acc ccg gct gca ggc acc agt ctc tgc ctt aca gtc     1392
 Ile Val Leu Ser Thr Pro Ala Ala Gly Thr Ser Leu Cys Leu Thr Val
     450                 455                 460

 gtg ttg atg gag gtg tca gta gat tat gtg gcc tgc cca ggt tca cat     1440
 Val Leu Met Glu Val Ser Val Asp Tyr Val Ala Cys Pro Gly Ser His
 465                 470                 475                 480

 ggg acc tgc ata gta gag caa aag tca gtg ccc tga                     1476
 Gly Thr Cys Ile Val Glu Gln Lys Ser Val Pro 
                 485                 490





      <210> 701
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 701
  atg aag gtg gtc ctg cgt gga ctg tgc agg tcg att ttg ctg gct cta      48
  Met Lys Val Val Leu Arg Gly Leu Cys Arg Ser Ile Leu Leu Ala Leu
    1               5                  10                  15

 cct agc ctg ggc aca ctg cag aag ttt gtg gat gac ctc ttt gag acc       96
 Pro Ser Leu Gly Thr Leu Gln Lys Phe Val Asp Asp Leu Phe Glu Thr
              20                  25                  30

 atc ttc agc acg gca cac cgt ggc tct gcc ctg ccc ctg gcc atc aag      144
 Ile Phe Ser Thr Ala His Arg Gly Ser Ala Leu Pro Leu Ala Ile Lys
          35                  40                  45

 tac atg ttt gac ttc ctg gat gag cag gct gat aaa cat ggc att cat      192
 Tyr Met Phe Asp Phe Leu Asp Glu Gln Ala Asp Lys His Gly Ile His
      50                  55                  60

 gac ccg cac gtc cgc cat acc tgg aag agc aat tgt agg act gtc ccc      240
 Asp Pro His Val Arg His Thr Trp Lys Ser Asn Cys Arg Thr Val Pro
  65                  70                  75                  80

 aaa aga aag cca tac aac cag tca gcc ccc aag gaa aag ctg att ccc      288
 Lys Arg Lys Pro Tyr Asn Gln Ser Ala Pro Lys Glu Lys Leu Ile Pro
                  85                  90                  95

 tct gac ata gct cat tct cag gcc tac ctg gca aca tca gat tcc tga      336
 Ser Asp Ile Ala His Ser Gln Ala Tyr Leu Ala Thr Ser Asp Ser 
             100                 105                 110





      <210> 702
      <211> 357
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(357)

      <400> 702
  atg ctt gcc aac cta agc ccc agc act ttt att ctg ctt tcc aga atg      48
  Met Leu Ala Asn Leu Ser Pro Ser Thr Phe Ile Leu Leu Ser Arg Met
    1               5                  10                  15

 tgc aga ggt tac gta cat cat ctg aat ggc cca gtg ttc tgc agg ctt       96
 Cys Arg Gly Tyr Val His His Leu Asn Gly Pro Val Phe Cys Arg Leu
              20                  25                  30

 acc ttt ttg tct tcc agt ggc aac gtg ttt tcc cca ctg tgt gct tct      144
 Thr Phe Leu Ser Ser Ser Gly Asn Val Phe Ser Pro Leu Cys Ala Ser
          35                  40                  45

 tct cca agc agc att cac aag gtt tat tac cca gaa ctc ttt gtc tgg      192
 Ser Pro Ser Ser Ile His Lys Val Tyr Tyr Pro Glu Leu Phe Val Trp
      50                  55                  60

 gtc agt caa gaa cca ttt cca aac aag gac atg gag gga agg ctt cct      240
 Val Ser Gln Glu Pro Phe Pro Asn Lys Asp Met Glu Gly Arg Leu Pro
  65                  70                  75                  80

 aag aaa gcc agc cct gct gtg cta ggt ctt gtc tca cac aaa gac atg      288
 Lys Lys Ala Ser Pro Ala Val Leu Gly Leu Val Ser His Lys Asp Met
                  85                  90                  95

 ctc cca ggg gtg ggc acc gtg gat cat ggt att cag gtc ttc tgc tat      336
 Leu Pro Gly Val Gly Thr Val Asp His Gly Ile Gln Val Phe Cys Tyr
             100                 105                 110

 ttt aag ttc ttt ctt ctc taa                                          357
 Phe Lys Phe Phe Leu Leu 
         115





      <210> 703
      <211> 285
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(285)

      <400> 703
  atg gcc agg cct cag ccg gca gcg tgg tgc tcg gta aga gcc ttg gct      48
  Met Ala Arg Pro Gln Pro Ala Ala Trp Cys Ser Val Arg Ala Leu Ala
    1               5                  10                  15

 ggg ctg cca gga gcc ctg ggt tcc agt cac aac tct gtc tcc aac tca       96
 Gly Leu Pro Gly Ala Leu Gly Ser Ser His Asn Ser Val Ser Asn Ser
              20                  25                  30

 ctg cgt ccc cgg tgt gaa agc tgt gga gcc gtt ttc cat tct gaa tgc      144
 Leu Arg Pro Arg Cys Glu Ser Cys Gly Ala Val Phe His Ser Glu Cys
          35                  40                  45

 aaa gaa aag tct gtc ccc tgc ccg agg tgt gtt cgc cga gag ctg cag      192
 Lys Glu Lys Ser Val Pro Cys Pro Arg Cys Val Arg Arg Glu Leu Gln
      50                  55                  60

 aag aag cag aag tct ttc tgg cag aga ctg aac atg gac gag agt cta      240
 Lys Lys Gln Lys Ser Phe Trp Gln Arg Leu Asn Met Asp Glu Ser Leu
  65                  70                  75                  80

 gag gag gct tgc acc atg ttc gag ctg tcc tac cag aac acc tga          285
 Glu Glu Ala Cys Thr Met Phe Glu Leu Ser Tyr Gln Asn Thr 
                  85                  90





      <210> 704
      <211> 468
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(468)

      <400> 704
  atg cag ctt ggg gga ctg gct gtc ggc ctg ggc ttc ttg ggc agc cgc      48
  Met Gln Leu Gly Gly Leu Ala Val Gly Leu Gly Phe Leu Gly Ser Arg
    1               5                  10                  15

 gat gag ctt ctg aca ggc cca agt acc ctt att cca gac ggt gtc cag       96
 Asp Glu Leu Leu Thr Gly Pro Ser Thr Leu Ile Pro Asp Gly Val Gln
              20                  25                  30

 aag gcg cct ggc caa gtg gga gag agg ctg gcc cag gag gcg aaa tct      144
 Lys Ala Pro Gly Gln Val Gly Glu Arg Leu Ala Gln Glu Ala Lys Ser
          35                  40                  45

 gtc agt cta tct gca ttg cct ttt gat ctc tac ttc agt tac tac aac      192
 Val Ser Leu Ser Ala Leu Pro Phe Asp Leu Tyr Phe Ser Tyr Tyr Asn
      50                  55                  60

 ttc aaa gac acc att gtc ctc ccc aag gga agc caa aaa tca gac agg      240
 Phe Lys Asp Thr Ile Val Leu Pro Lys Gly Ser Gln Lys Ser Asp Arg
  65                  70                  75                  80

 gtg gtg gcc tgc cca gaa tca cac aat gag tca ggg ctg agc tgc agc      288
 Val Val Ala Cys Pro Glu Ser His Asn Glu Ser Gly Leu Ser Cys Ser
                  85                  90                  95

 cac agc ctc ggt gac cac ttc tct gca ttc acc ccg cca ttc att cat      336
 His Ser Leu Gly Asp His Phe Ser Ala Phe Thr Pro Pro Phe Ile His
             100                 105                 110

 gca cac aat gac tta ctg agc acc cac tat gtg gca ggc act gtg ctg      384
 Ala His Asn Asp Leu Leu Ser Thr His Tyr Val Ala Gly Thr Val Leu
         115                 120                 125

 ggt gct aga gac aca gat aat gat aca gac aaa gtc cct gcc att gtg      432
 Gly Ala Arg Asp Thr Asp Asn Asp Thr Asp Lys Val Pro Ala Ile Val
     130                 135                 140

 gca ttt gag aca gga act gca caa gta tac aaa taa                      468
 Ala Phe Glu Thr Gly Thr Ala Gln Val Tyr Lys 
 145                 150                 155





      <210> 705
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 705
  atg gct cca gac aca aag ctt cta ctg tct tct cgt gga gcc aga tgt      48
  Met Ala Pro Asp Thr Lys Leu Leu Leu Ser Ser Arg Gly Ala Arg Cys
    1               5                  10                  15

 gct acc ctc cta gca ctg ctg cct caa gcc ttg gtc ggc cag gcc ttc       96
 Ala Thr Leu Leu Ala Leu Leu Pro Gln Ala Leu Val Gly Gln Ala Phe
              20                  25                  30

 cag gat gaa aag gtg tgt ctt ccc gtc cag cag gtg gaa gcc agt gag      144
 Gln Asp Glu Lys Val Cys Leu Pro Val Gln Gln Val Glu Ala Ser Glu
          35                  40                  45

 cac atc cag ggt cct gac agg gta gga gtc cag gcc gag ggc ctt agc      192
 His Ile Gln Gly Pro Asp Arg Val Gly Val Gln Ala Glu Gly Leu Ser
      50                  55                  60

 gtt gat cat ggt gat gtc ctg cag cag gct gtg gag cag gga gac ctt      240
 Val Asp His Gly Asp Val Leu Gln Gln Ala Val Glu Gln Gly Asp Leu
  65                  70                  75                  80

 ctt aaa gtc aaa gac gaa gat gat gcg gcc aaa ctg gga gcc ccc aag      288
 Leu Lys Val Lys Asp Glu Asp Asp Ala Ala Lys Leu Gly Ala Pro Lys
                  85                  90                  95

 gtc agg atc agc agc tct ggc ccc ggc cct cag tgg cac cgc gat gtc      336
 Val Arg Ile Ser Ser Ser Gly Pro Gly Pro Gln Trp His Arg Asp Val
             100                 105                 110

 cac tcg caa ctt gag ctg gga gtc agc ctc tag                          369
 His Ser Gln Leu Glu Leu Gly Val Ser Leu 
         115                 120





      <210> 706
      <211> 1302
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1302)

      <400> 706
  atg gtg gcg ccc gcg gct cgg gtc ttc ctc cgg gca gtg cgc gcg gct      48
  Met Val Ala Pro Ala Ala Arg Val Phe Leu Arg Ala Val Arg Ala Ala
    1               5                  10                  15

 ctc act tcc acg gtc ccg gac ctg ctc tgc ctc ctg gcc cga ggc tcc       96
 Leu Thr Ser Thr Val Pro Asp Leu Leu Cys Leu Leu Ala Arg Gly Ser
              20                  25                  30

 ccg cgt ggc ctc gcg tct ggt cgc cta ccc ctc gcg gtc cac tcc gcc      144
 Pro Arg Gly Leu Ala Ser Gly Arg Leu Pro Leu Ala Val His Ser Ala
          35                  40                  45

 cag cat gga cct gga tcc ggg gcg cct tgg ttg cga att gcc agg agg      192
 Gln His Gly Pro Gly Ser Gly Ala Pro Trp Leu Arg Ile Ala Arg Arg
      50                  55                  60

 gcc ctg aga ttt gtg ttg tca aaa cac tgg ggg gat gat tgt tac ctg      240
 Ala Leu Arg Phe Val Leu Ser Lys His Trp Gly Asp Asp Cys Tyr Leu
  65                  70                  75                  80

 aca aac cgc ctc tgg cag gac ctg aag cct ccc agt cac gtc gag aac      288
 Thr Asn Arg Leu Trp Gln Asp Leu Lys Pro Pro Ser His Val Glu Asn
                  85                  90                  95

 ggg cag gag ctc agg ttg gcg ccg ccg gtg cag tgg gca tta cag cca      336
 Gly Gln Glu Leu Arg Leu Ala Pro Pro Val Gln Trp Ala Leu Gln Pro
             100                 105                 110

 aag aat tta gaa cga gtc tac gtg gac acg caa gtt tca gcg agc ggg      384
 Lys Asn Leu Glu Arg Val Tyr Val Asp Thr Gln Val Ser Ala Ser Gly
         115                 120                 125

 gat ttc ctg cga ggc cga gcg cga gga aca gcc ggc ccc gga ggc tcg      432
 Asp Phe Leu Arg Gly Arg Ala Arg Gly Thr Ala Gly Pro Gly Gly Ser
     130                 135                 140

 ggc tcg ggg tct ccc cgg gga cgc ggc cga ctg aga agg ccg ggg cgc      480
 Gly Ser Gly Ser Pro Arg Gly Arg Gly Arg Leu Arg Arg Pro Gly Arg
 145                 150                 155                 160

 tcg ccg ggc gcg gcg ccg tcc tcc gtg tcg cgg gga cgg aag gag gcg      528
 Ser Pro Gly Ala Ala Pro Ser Ser Val Ser Arg Gly Arg Lys Glu Ala
                 165                 170                 175

 acg cag gcc agg agt cgt gcg cgc ggg cgg cga ggg ggc gct gtg gcc      576
 Thr Gln Ala Arg Ser Arg Ala Arg Gly Arg Arg Gly Gly Ala Val Ala
             180                 185                 190

 cgt gtc tgc cgg ccc gag tcc cgg caa cgg tcg cac ctc tcc ccg ccc      624
 Arg Val Cys Arg Pro Glu Ser Arg Gln Arg Ser His Leu Ser Pro Pro
         195                 200                 205

 ggg tcg gga gcc cct cgt ggc cag gcg tcc gcg cgg ctc aag acc gag      672
 Gly Ser Gly Ala Pro Arg Gly Gln Ala Ser Ala Arg Leu Lys Thr Glu
     210                 215                 220

 gtc cgc cac gct ggg ccg ctc gtg ggc ggc tct cac ccg gca tac cgt      720
 Val Arg His Ala Gly Pro Leu Val Gly Gly Ser His Pro Ala Tyr Arg
 225                 230                 235                 240

 gga aac ggc gcg tcc cgc cag ctg cgg ctc cag cct ggg agg gag cgc      768
 Gly Asn Gly Ala Ser Arg Gln Leu Arg Leu Gln Pro Gly Arg Glu Arg
                 245                 250                 255

 agc gcg ggg agc ctg cag cgt ctg gag agt gag gaa aag gga cat tcc      816
 Ser Ala Gly Ser Leu Gln Arg Leu Glu Ser Glu Glu Lys Gly His Ser
             260                 265                 270

 ttg gaa atg gac aga gcc gag ttc ctt aaa ggg atc gca gtt gaa aga      864
 Leu Glu Met Asp Arg Ala Glu Phe Leu Lys Gly Ile Ala Val Glu Arg
         275                 280                 285

 gac cct ctt caa aat cag caa cga cct ggc agc ctt agt tcc tca aca      912
 Asp Pro Leu Gln Asn Gln Gln Arg Pro Gly Ser Leu Ser Ser Ser Thr
     290                 295                 300

 gga gat ggt tcg aag atg aaa tgt ttg aaa ctc cgc cgc cgt ttc acc      960
 Gly Asp Gly Ser Lys Met Lys Cys Leu Lys Leu Arg Arg Arg Phe Thr
 305                 310                 315                 320

 ttt gca cac acg cgc acg gca ggc cca gat ccg cac aga gac gca gac     1008
 Phe Ala His Thr Arg Thr Ala Gly Pro Asp Pro His Arg Asp Ala Asp
                 325                 330                 335

 acg cgc gcg ctc gcg ctt ccc gga gag cgt aga aca cag ggc ctt tct     1056
 Thr Arg Ala Leu Ala Leu Pro Gly Glu Arg Arg Thr Gln Gly Leu Ser
             340                 345                 350

 ggc cag tat gct cct tcc aga aac aac cag ttc tgc cta gtt ctc ttc     1104
 Gly Gln Tyr Ala Pro Ser Arg Asn Asn Gln Phe Cys Leu Val Leu Phe
         355                 360                 365

 act gtg gcc aga aga agc tgg atc ttt gca aat aca aat ctg ctg aga     1152
 Thr Val Ala Arg Arg Ser Trp Ile Phe Ala Asn Thr Asn Leu Leu Arg
     370                 375                 380

 gcc cca gca cag tgg gag gcc atc ggg gct ggc ctt gta tta gag aca     1200
 Ala Pro Ala Gln Trp Glu Ala Ile Gly Ala Gly Leu Val Leu Glu Thr
 385                 390                 395                 400

 ggc ctc atg gga ggt gtc gag gtc atg gat gca gag tgg cct cca gta     1248
 Gly Leu Met Gly Gly Val Glu Val Met Asp Ala Glu Trp Pro Pro Val
                 405                 410                 415

 tta gag gtg gac ctc atg gga ggt gtc gag gcc atg gat gca aag tcc     1296
 Leu Glu Val Asp Leu Met Gly Gly Val Glu Ala Met Asp Ala Lys Ser
             420                 425                 430

 tca tga                                                             1302
 Ser 






      <210> 707
      <211> 165
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(165)

      <400> 707
  atg gat gta gcc acc tgt ttc ttg aac ttc tct gca gcc acc tca ttg      48
  Met Asp Val Ala Thr Cys Phe Leu Asn Phe Ser Ala Ala Thr Ser Leu
    1               5                  10                  15

 gca atg ttg gct ccc atc agc aca ctg atg tca ata ccc atc ttc tca       96
 Ala Met Leu Ala Pro Ile Ser Thr Leu Met Ser Ile Pro Ile Phe Ser
              20                  25                  30

 cgg atg atg tca gaa atg agc ttc agc ccc tcg ggg ccc tcg tct atg      144
 Arg Met Met Ser Glu Met Ser Phe Ser Pro Ser Gly Pro Ser Ser Met
          35                  40                  45

 ccc tac aag gat gcc aag tga                                          165
 Pro Tyr Lys Asp Ala Lys 
      50





      <210> 708
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 708
  atg gtg atg gcc agt gtc atg cag aag att ata cct cgc tat tct ctt      48
  Met Val Met Ala Ser Val Met Gln Lys Ile Ile Pro Arg Tyr Ser Leu
    1               5                  10                  15

 gct caa tgg cta ctc tgt aat ggc agt ttg agg tgg tat caa cat tct       96
 Ala Gln Trp Leu Leu Cys Asn Gly Ser Leu Arg Trp Tyr Gln His Ser
              20                  25                  30

 aca gta gaa gaa tca aga att ctt gca ggg aat cag caa aaa gag aaa      144
 Thr Val Glu Glu Ser Arg Ile Leu Ala Gly Asn Gln Gln Lys Glu Lys
          35                  40                  45

 agc aaa aaa gat agg aaa tat aat ggt cac act gaa agt aag cca tta      192
 Ser Lys Lys Asp Arg Lys Tyr Asn Gly His Thr Glu Ser Lys Pro Leu
      50                  55                  60

 acc att cca aag gat att gac ctt cgt cta gaa aca aag tca gtt aca      240
 Thr Ile Pro Lys Asp Ile Asp Leu Arg Leu Glu Thr Lys Ser Val Thr
  65                  70                  75                  80

 gaa gtg gat aca tta gca ttg cat tac ttc cca gaa tac caa caa cct      288
 Glu Val Asp Thr Leu Ala Leu His Tyr Phe Pro Glu Tyr Gln Gln Pro
                  85                  90                  95

 ggc tat tct gtc aga cct gag aaa ttt atg ctg ttc ttt agt tca acc      336
 Gly Tyr Ser Val Arg Pro Glu Lys Phe Met Leu Phe Phe Ser Ser Thr
             100                 105                 110

 ctg gtt cat agg aac tcc tcc aca gct caa gac caa gcc act gtg aca      384
 Leu Val His Arg Asn Ser Ser Thr Ala Gln Asp Gln Ala Thr Val Thr
         115                 120                 125

 gct gtc acc ctg ctc aag tcc ttg gga taa                              414
 Ala Val Thr Leu Leu Lys Ser Leu Gly 
     130                 135





      <210> 709
      <211> 558
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(558)

      <400> 709
  atg acg cct ggg cca gcg tca ccc aca cac cag ccc ctg gcc aca cag      48
  Met Thr Pro Gly Pro Ala Ser Pro Thr His Gln Pro Leu Ala Thr Gln
    1               5                  10                  15

 ctg ctg atc act ctg tac atg gct ggt gcc gcg gcc agg tgg gac ctc       96
 Leu Leu Ile Thr Leu Tyr Met Ala Gly Ala Ala Ala Arg Trp Asp Leu
              20                  25                  30

 tgc att gat cag gct gtg gtc ttc atc gaa gat gct att cag gtt aag      144
 Cys Ile Asp Gln Ala Val Val Phe Ile Glu Asp Ala Ile Gln Val Lys
          35                  40                  45

 aga act gag ggt gga gcc tct ggg cac ggc tct tcg tca gtc ccc gga      192
 Arg Thr Glu Gly Gly Ala Ser Gly His Gly Ser Ser Ser Val Pro Gly
      50                  55                  60

 gga ctt gtc ttc tgc atc ctg gac gca ttt gct gct ttg atg cac cgt      240
 Gly Leu Val Phe Cys Ile Leu Asp Ala Phe Ala Ala Leu Met His Arg
  65                  70                  75                  80

 gtt ctg agg cct gtt gtg gac cac ccc att cta ggt ggg ctg gac ctg      288
 Val Leu Arg Pro Val Val Asp His Pro Ile Leu Gly Gly Leu Asp Leu
                  85                  90                  95

 gtg act tgc ttc tac ctg ata gaa tac agc aag agt gat gag atg tca      336
 Val Thr Cys Phe Tyr Leu Ile Glu Tyr Ser Lys Ser Asp Glu Met Ser
             100                 105                 110

 ctt ccg aga tta ggt tgg acg gat ggt gac ttc cag ctt gtt agt ctt      384
 Leu Pro Arg Leu Gly Trp Thr Asp Gly Asp Phe Gln Leu Val Ser Leu
         115                 120                 125

 ctc tcg ggc tct tct tgt ttg ctt gct ctg gtg aag cca gcc acc ata      432
 Leu Ser Gly Ser Ser Cys Leu Leu Ala Leu Val Lys Pro Ala Thr Ile
     130                 135                 140

 tgt act gaa ggc gcc aga aca tat gtc acg gcc acc ctt gtc ctg ggg      480
 Cys Thr Glu Gly Ala Arg Thr Tyr Val Thr Ala Thr Leu Val Leu Gly
 145                 150                 155                 160

 gtc tcg gcc agc aag gcc tgg act cca gat cac agc cct gca ctg gaa      528
 Val Ser Ala Ser Lys Ala Trp Thr Pro Asp His Ser Pro Ala Leu Glu
                 165                 170                 175

 gtc aac gag gaa aca gcc ccc aac atg tga                              558
 Val Asn Glu Glu Thr Ala Pro Asn Met 
             180                 185





      <210> 710
      <211> 936
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(936)

      <400> 710
  atg agt ctg aag gcc atg gac tgt ttt ctc tgc atc ctg atg ctg agc      48
  Met Ser Leu Lys Ala Met Asp Cys Phe Leu Cys Ile Leu Met Leu Ser
    1               5                  10                  15

 cca agg cct gcc cca ggg cag gca ctt tgg gca cag ggt cag aag gga       96
 Pro Arg Pro Ala Pro Gly Gln Ala Leu Trp Ala Gln Gly Gln Lys Gly
              20                  25                  30

 gcg cgt aag tac cac tgc atg cgc cag cgc agt ggc gca gtg aca gag      144
 Ala Arg Lys Tyr His Cys Met Arg Gln Arg Ser Gly Ala Val Thr Glu
          35                  40                  45

 atg gtg cca tgc gct cct gag ctt aca aca cgt gtt tcc aga gtg gtc      192
 Met Val Pro Cys Ala Pro Glu Leu Thr Thr Arg Val Ser Arg Val Val
      50                  55                  60

 aca gct ggc gtg gag cct gac ctc gtg gct tcg ggg ctc atg ctg tcg      240
 Thr Ala Gly Val Glu Pro Asp Leu Val Ala Ser Gly Leu Met Leu Ser
  65                  70                  75                  80

 cta cgg agc acc atg gca ttc ccc tgg gta gtg tgg ccc aag att cgt      288
 Leu Arg Ser Thr Met Ala Phe Pro Trp Val Val Trp Pro Lys Ile Arg
                  85                  90                  95

 gtc tgc atc cat caa gca act gcc atc tac cag gcc ctg tgc agc ctc      336
 Val Cys Ile His Gln Ala Thr Ala Ile Tyr Gln Ala Leu Cys Ser Leu
             100                 105                 110

 tgg gga tac aga ttg gaa aga gcc tcc ccc tgc acc cca ctg ctg ctg      384
 Trp Gly Tyr Arg Leu Glu Arg Ala Ser Pro Cys Thr Pro Leu Leu Leu
         115                 120                 125

 tca tcc att cct gac cgc cag atc tta cca gga gca agc atc cca ggc      432
 Ser Ser Ile Pro Asp Arg Gln Ile Leu Pro Gly Ala Ser Ile Pro Gly
     130                 135                 140

 ttc tca ctg tcc gca cct ccc ctt gcc tgg ctc cat cag gag cgc ctc      480
 Phe Ser Leu Ser Ala Pro Pro Leu Ala Trp Leu His Gln Glu Arg Leu
 145                 150                 155                 160

 ttt ccc tat ggc tgc tgt ggc tgc ctc tgc ttt ctt gct cct ttt caa      528
 Phe Pro Tyr Gly Cys Cys Gly Cys Leu Cys Phe Leu Ala Pro Phe Gln
                 165                 170                 175

 gcc aag tgc agc ctg gcg agg aag cct ttc cca ggt gcc cag gca ttt      576
 Ala Lys Cys Ser Leu Ala Arg Lys Pro Phe Pro Gly Ala Gln Ala Phe
             180                 185                 190

 gtg ccc agc aga gca ggg acc aac cgt ggg tgt gac cag aag ttt cca      624
 Val Pro Ser Arg Ala Gly Thr Asn Arg Gly Cys Asp Gln Lys Phe Pro
         195                 200                 205

 ctt ggc acc atc tct gcc acc ctt ccc atc atc ctg act ctc ccc ctc      672
 Leu Gly Thr Ile Ser Ala Thr Leu Pro Ile Ile Leu Thr Leu Pro Leu
     210                 215                 220

 ttt gcc tcc acg gac cac tac ttc ctg cac gcg ggc cat tct gac ccc      720
 Phe Ala Ser Thr Asp His Tyr Phe Leu His Ala Gly His Ser Asp Pro
 225                 230                 235                 240

 ctc ttc atg aca gaa act ttt gta tcc tcc ttc aag gcc ttg ttg tcc      768
 Leu Phe Met Thr Glu Thr Phe Val Ser Ser Phe Lys Ala Leu Leu Ser
                 245                 250                 255

 tcc tgg tgc gaa gag ctc ggc cgc ctg ctg ctg ctc cga cat cag aag      816
 Ser Trp Cys Glu Glu Leu Gly Arg Leu Leu Leu Leu Arg His Gln Lys
             260                 265                 270

 agc cgc cag agc gat ccc cct ggg aaa ctc ccc atg cag ccc cct ctc      864
 Ser Arg Gln Ser Asp Pro Pro Gly Lys Leu Pro Met Gln Pro Pro Leu
         275                 280                 285

 agc tcc atg agc tcc atg aaa ccc act ctg tcg cac aga atc atc ctc      912
 Ser Ser Met Ser Ser Met Lys Pro Thr Leu Ser His Arg Ile Ile Leu
     290                 295                 300

 ctc tca tca tcc tat gtg tca tga                                      936
 Leu Ser Ser Ser Tyr Val Ser 
 305                 310





      <210> 711
      <211> 477
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(477)

      <400> 711
  atg ggc ctg tgg gcg ctg tgg gga cac ctt gct gcc agg agc ctt ggg      48
  Met Gly Leu Trp Ala Leu Trp Gly His Leu Ala Ala Arg Ser Leu Gly
    1               5                  10                  15

 gct gtg ggg ggc tgg agg gaa gtg atg ctg ggt aga aat gga gga acc       96
 Ala Val Gly Gly Trp Arg Glu Val Met Leu Gly Arg Asn Gly Gly Thr
              20                  25                  30

 aga gcc agc aaa gcc cag ttg gcc aga gca gga att gtt agg aat gca      144
 Arg Ala Ser Lys Ala Gln Leu Ala Arg Ala Gly Ile Val Arg Asn Ala
          35                  40                  45

 ggt gta agt gac cat gca cag cct cgg cct tct cta atg aca tca gag      192
 Gly Val Ser Asp His Ala Gln Pro Arg Pro Ser Leu Met Thr Ser Glu
      50                  55                  60

 aag aca gca gcc ctg ccc ctg act cag gac aag ctt gct aca gga aat      240
 Lys Thr Ala Ala Leu Pro Leu Thr Gln Asp Lys Leu Ala Thr Gly Asn
  65                  70                  75                  80

 gag gtc aac aga cga gca gct ggc cac cag gca gag caa agc cac tca      288
 Glu Val Asn Arg Arg Ala Ala Gly His Gln Ala Glu Gln Ser His Ser
                  85                  90                  95

 ttt act cca cta gta ctt act gtg tac cct cta gag gcc aga tcc tgg      336
 Phe Thr Pro Leu Val Leu Thr Val Tyr Pro Leu Glu Ala Arg Ser Trp
             100                 105                 110

 gga gca gtt tcg gag cag gca cag aaa cac gag gca gga tcc ttg act      384
 Gly Ala Val Ser Glu Gln Ala Gln Lys His Glu Ala Gly Ser Leu Thr
         115                 120                 125

 tca ggg acc tca ctg cag ggt acc tca tca aat ctg ctt aca cag tcc      432
 Ser Gly Thr Ser Leu Gln Gly Thr Ser Ser Asn Leu Leu Thr Gln Ser
     130                 135                 140

 ggg tat caa gca cca tct aga agt gat ttc agt gtg ggc ctc taa          477
 Gly Tyr Gln Ala Pro Ser Arg Ser Asp Phe Ser Val Gly Leu 
 145                 150                 155





      <210> 712
      <211> 777
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(777)

      <400> 712
  atg act cct ccg aag ctg cga gcg tcg ctg tcg ccg tcg ctg ctg ctg      48
  Met Thr Pro Pro Lys Leu Arg Ala Ser Leu Ser Pro Ser Leu Leu Leu
    1               5                  10                  15

 ctg ctg agt ggt tgc ctc ctc gcg gct gct cgg agg gag aaa ggg gcg       96
 Leu Leu Ser Gly Cys Leu Leu Ala Ala Ala Arg Arg Glu Lys Gly Ala
              20                  25                  30

 gct agc aac gtg gcg gag cct gtc ccc ggg ccc act ggc tgc tcc tcg      144
 Ala Ser Asn Val Ala Glu Pro Val Pro Gly Pro Thr Gly Cys Ser Ser
          35                  40                  45

 ggt cgc ttc ctc agc ccc gag cag cac gcg tgc agc tgg cag ctc ctg      192
 Gly Arg Phe Leu Ser Pro Glu Gln His Ala Cys Ser Trp Gln Leu Leu
      50                  55                  60

 ctg ccc gcc ccg gag gcc gca gcg ggc agc gag ctg gcg ctg cgc tgc      240
 Leu Pro Ala Pro Glu Ala Ala Ala Gly Ser Glu Leu Ala Leu Arg Cys
  65                  70                  75                  80

 cag agc ccg gac ggg gcg cgc cac cag tgc gcc tac cgc ggg cat ccg      288
 Gln Ser Pro Asp Gly Ala Arg His Gln Cys Ala Tyr Arg Gly His Pro
                  85                  90                  95

 gag cgc tgc gca gcc tac gcc gct cgc cgc gcg cac ttc tgg aag cag      336
 Glu Arg Cys Ala Ala Tyr Ala Ala Arg Arg Ala His Phe Trp Lys Gln
             100                 105                 110

 gtg ctg gga ggg ctg cgc aag aag cgg agg ccc tgt cac gac ccc gcg      384
 Val Leu Gly Gly Leu Arg Lys Lys Arg Arg Pro Cys His Asp Pro Ala
         115                 120                 125

 ccg ctc cag gcc cgc ttg tgc gcg ggc aag aag ggc cac ggc gcc gag      432
 Pro Leu Gln Ala Arg Leu Cys Ala Gly Lys Lys Gly His Gly Ala Glu
     130                 135                 140

 ctg cgg cta gtg ccc cgc gcg tcc ccg ccc gca cgc ccc acc gtc gcg      480
 Leu Arg Leu Val Pro Arg Ala Ser Pro Pro Ala Arg Pro Thr Val Ala
 145                 150                 155                 160

 gga ttc gcg ggg gag tcc aag ccc cgg gcc cgg aac cgg ggg cgg acc      528
 Gly Phe Ala Gly Glu Ser Lys Pro Arg Ala Arg Asn Arg Gly Arg Thr
                 165                 170                 175

 cgg gag cgt gcg tcc ggc cca gcc gct ggg acc ccg cct ccc caa agc      576
 Arg Glu Arg Ala Ser Gly Pro Ala Ala Gly Thr Pro Pro Pro Gln Ser
             180                 185                 190

 gca ccg ccc aaa gaa aac ccc tca gag agg aag acc aac gag ggc aag      624
 Ala Pro Pro Lys Glu Asn Pro Ser Glu Arg Lys Thr Asn Glu Gly Lys
         195                 200                 205

 agg aag gcg gcc ttg gtc ccc aac gag gag cga ccc atg ggg acc ggg      672
 Arg Lys Ala Ala Leu Val Pro Asn Glu Glu Arg Pro Met Gly Thr Gly
     210                 215                 220

 ccc gac ccc gac ggg ctg gac ggg aac gcg gag ctc acg gag acc tac      720
 Pro Asp Pro Asp Gly Leu Asp Gly Asn Ala Glu Leu Thr Glu Thr Tyr
 225                 230                 235                 240

 tgc gct gag aag tgg cac tcc ctc tgc aac ttc ttt gtc aat ttc tgg      768
 Cys Ala Glu Lys Trp His Ser Leu Cys Asn Phe Phe Val Asn Phe Trp
                 245                 250                 255

 aac ggc tga                                                          777
 Asn Gly 






      <210> 713
      <211> 462
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(462)

      <400> 713
  atg gct gac tgg gag ctg tgg ctc act gct gct atg ctc agc atc atg      48
  Met Ala Asp Trp Glu Leu Trp Leu Thr Ala Ala Met Leu Ser Ile Met
    1               5                  10                  15

 ata gag tat tgt atc act ttc tgt gag ctg aag cag aag ctg gat gag       96
 Ile Glu Tyr Cys Ile Thr Phe Cys Glu Leu Lys Gln Lys Leu Asp Glu
              20                  25                  30

 gaa ggc agc aag tgc agc atc ctc tcg aag cac cag cag ttt gtg gag      144
 Glu Gly Ser Lys Cys Ser Ile Leu Ser Lys His Gln Gln Phe Val Glu
          35                  40                  45

 cac tgc tgc atg cgc tgc tgc tcg ccc ttc acc ttc ctc gtc aac acc      192
 His Cys Cys Met Arg Cys Cys Ser Pro Phe Thr Phe Leu Val Asn Thr
      50                  55                  60

 aag cgc cag tgt gga gat tgc aaa ttc aat gtc tgc aag agc tgc tgc      240
 Lys Arg Gln Cys Gly Asp Cys Lys Phe Asn Val Cys Lys Ser Cys Cys
  65                  70                  75                  80

 tcc tac cag aag cac gaa aag gcc tgg gtc tgc tgc gtc tgc cag caa      288
 Ser Tyr Gln Lys His Glu Lys Ala Trp Val Cys Cys Val Cys Gln Gln
                  85                  90                  95

 gcg agg aac ctg tct agg aaa gaa atc cat gaa ata tgt ggc ata ttt      336
 Ala Arg Asn Leu Ser Arg Lys Glu Ile His Glu Ile Cys Gly Ile Phe
             100                 105                 110

 ttg cat cct gaa atg tct cta agg ccc tgt ttg aca gag aag tat gtc      384
 Leu His Pro Glu Met Ser Leu Arg Pro Cys Leu Thr Glu Lys Tyr Val
         115                 120                 125

 ttt caa agt acc acg gat gta tgg cct gtg agc gga cag tct ttt atg      432
 Phe Gln Ser Thr Thr Asp Val Trp Pro Val Ser Gly Gln Ser Phe Met
     130                 135                 140

 ttg tac ctg gat cac att ctt gtt ttt tga                              462
 Leu Tyr Leu Asp His Ile Leu Val Phe 
 145                 150





      <210> 714
      <211> 651
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(651)

      <400> 714
  atg ctc cgc cat ctg ggc tcc caa gct gcc gtc gcc ctc tgt gtg cag      48
  Met Leu Arg His Leu Gly Ser Gln Ala Ala Val Ala Leu Cys Val Gln
    1               5                  10                  15

 gca gca gct gcc tgg caa ccc ccg agc ccg ctc gcg ctc cta gca tca       96
 Ala Ala Ala Ala Trp Gln Pro Pro Ser Pro Leu Ala Leu Leu Ala Ser
              20                  25                  30

 cag aag cag ggc cac gtg tcc cag tgg ctg cag cca agc cag gca ttc      144
 Gln Lys Gln Gly His Val Ser Gln Trp Leu Gln Pro Ser Gln Ala Phe
          35                  40                  45

 tgc cct gcg gca gca gct gca cag gag cga gaa ctg aga acc cac cgc      192
 Cys Pro Ala Ala Ala Ala Ala Gln Glu Arg Glu Leu Arg Thr His Arg
      50                  55                  60

 tca acc cca cac gag gtg act gcc gag tgc cca tac aaa cgg ctc cga      240
 Ser Thr Pro His Glu Val Thr Ala Glu Cys Pro Tyr Lys Arg Leu Arg
  65                  70                  75                  80

 tct ccc tca ggg atc atg gca caa gtt gca gat tcc acc ctg ccc atg      288
 Ser Pro Ser Gly Ile Met Ala Gln Val Ala Asp Ser Thr Leu Pro Met
                  85                  90                  95

 gaa gat gag gag tcc atg gaa gat gag gag tct gtt gaa gat gat tcc      336
 Glu Asp Glu Glu Ser Met Glu Asp Glu Glu Ser Val Glu Asp Asp Ser
             100                 105                 110

 gtg gag agc agg atg gtg gtg aca ttt ctc ata tca gct ctc gag tcc      384
 Val Glu Ser Arg Met Val Val Thr Phe Leu Ile Ser Ala Leu Glu Ser
         115                 120                 125

 acg ttt gat gat ctt acg gca gag gag gaa gct gta tct tca aaa tgt      432
 Thr Phe Asp Asp Leu Thr Ala Glu Glu Glu Ala Val Ser Ser Lys Cys
     130                 135                 140

 gtc aat ttg gct aaa gac aat caa gtt atc caa cag gag tta tta tct      480
 Val Asn Leu Ala Lys Asp Asn Gln Val Ile Gln Gln Glu Leu Leu Ser
 145                 150                 155                 160

 atg aaa aaa gta caa caa gaa tgt gaa aaa ctt gag gag aat caa aag      528
 Met Lys Lys Val Gln Gln Glu Cys Glu Lys Leu Glu Glu Asn Gln Lys
                 165                 170                 175

 atg ttg gaa gaa gaa ata tta aat ctc aag aca cat atg gaa aac agt      576
 Met Leu Glu Glu Glu Ile Leu Asn Leu Lys Thr His Met Glu Asn Ser
             180                 185                 190

 atc gta gaa ctt agt gag cta caa gaa tat aaa tca gag cta gat gaa      624
 Ile Val Glu Leu Ser Glu Leu Gln Glu Tyr Lys Ser Glu Leu Asp Glu
         195                 200                 205

 agg gca atg cag gca gta gaa aaa tga                                  651
 Arg Ala Met Gln Ala Val Glu Lys 
     210                 215





      <210> 715
      <211> 492
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(492)

      <400> 715
  atg gac cgc tgc ccc tcc atc ctg ccc ttg ccc gtg cgt ttg gtg ttt      48
  Met Asp Arg Cys Pro Ser Ile Leu Pro Leu Pro Val Arg Leu Val Phe
    1               5                  10                  15

 cag atc cta ctc acg gga ggc agc tgc gcg gag gag aca cag gtc cag       96
 Gln Ile Leu Leu Thr Gly Gly Ser Cys Ala Glu Glu Thr Gln Val Gln
              20                  25                  30

 gag ccc gtg agc att tgt gag agc aga gat ggc aag cac gtg cgt gga      144
 Glu Pro Val Ser Ile Cys Glu Ser Arg Asp Gly Lys His Val Arg Gly
          35                  40                  45

 gac caa cga agc gtg tcc ctg gca cac agc aag gga gag ttt cgc tcg      192
 Asp Gln Arg Ser Val Ser Leu Ala His Ser Lys Gly Glu Phe Arg Ser
      50                  55                  60

 gtc tct gca gtg cag tct cct ggc gta agt ctt gaa gat gga ccc aac      240
 Val Ser Ala Val Gln Ser Pro Gly Val Ser Leu Glu Asp Gly Pro Asn
  65                  70                  75                  80

 tcc ctg aag aaa tgg atc ttg aaa ttg aac aca aac atc atg aac aga      288
 Ser Leu Lys Lys Trp Ile Leu Lys Leu Asn Thr Asn Ile Met Asn Arg
                  85                  90                  95

 agg aaa tac tta ggc aag ccc atg tgt aac atg ctc aca gat gtg ctg      336
 Arg Lys Tyr Leu Gly Lys Pro Met Cys Asn Met Leu Thr Asp Val Leu
             100                 105                 110

 gct ttg cca atg ctt tcg gac tcc acc atg ctt tct gat tct tct ggt      384
 Ala Leu Pro Met Leu Ser Asp Ser Thr Met Leu Ser Asp Ser Ser Gly
         115                 120                 125

 cct agt cac gcc ttg gca cgg ggc aga agc ggc cga gct atg ctg aca      432
 Pro Ser His Ala Leu Ala Arg Gly Arg Ser Gly Arg Ala Met Leu Thr
     130                 135                 140

 ggt gct gct gag agc caa cag cca ttc agc cga gaa ggc gtt tct agt      480
 Gly Ala Ala Glu Ser Gln Gln Pro Phe Ser Arg Glu Gly Val Ser Ser
 145                 150                 155                 160

 atc tgg aaa tag                                                      492
 Ile Trp Lys 






      <210> 716
      <211> 180
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(180)

      <400> 716
  atg ctg tgg att ggc tca gtc aac atc cac ttc acc ctc aaa cag tat      48
  Met Leu Trp Ile Gly Ser Val Asn Ile His Phe Thr Leu Lys Gln Tyr
    1               5                  10                  15

 cct cta atc agc ttc ctg gct gtc atg aag ctt gac atg aac aat cta       96
 Pro Leu Ile Ser Phe Leu Ala Val Met Lys Leu Asp Met Asn Asn Leu
              20                  25                  30

 ttt ttc aat gtg gca gat gta ata ggc atc gct ttc tac cat ttt gtg      144
 Phe Phe Asn Val Ala Asp Val Ile Gly Ile Ala Phe Tyr His Phe Val
          35                  40                  45

 agt acc caa ttc cct ata ttc aac ctg tca gat tag                      180
 Ser Thr Gln Phe Pro Ile Phe Asn Leu Ser Asp 
      50                  55





      <210> 717
      <211> 1476
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1476)

      <400> 717
  atg atc ctt ctt cag ctt ctg caa ctc ctg ggc cgg gta tgt ggg tgt      48
  Met Ile Leu Leu Gln Leu Leu Gln Leu Leu Gly Arg Val Cys Gly Cys
    1               5                  10                  15

 tta gtt ctg tgg caa agg act cca gct cgt gtg gaa cac cca ggc cat       96
 Leu Val Leu Trp Gln Arg Thr Pro Ala Arg Val Glu His Pro Gly His
              20                  25                  30

 caa gga tcc cag ggc cat cca atc aac cgg cca atg acg gtt tca gag      144
 Gln Gly Ser Gln Gly His Pro Ile Asn Arg Pro Met Thr Val Ser Glu
          35                  40                  45

 aag cgg tcc tgg gga ggg gta tta tct gca gga aca cgt cct gcc aac      192
 Lys Arg Ser Trp Gly Gly Val Leu Ser Ala Gly Thr Arg Pro Ala Asn
      50                  55                  60

 ttt gta gtc gag tca cct att tcg gtt ggt agc ggc cgc tat ttc ttt      240
 Phe Val Val Glu Ser Pro Ile Ser Val Gly Ser Gly Arg Tyr Phe Phe
  65                  70                  75                  80

 aaa agg gca gtg gat ttc gaa aca gga ggg gga gag tcc agt aaa caa      288
 Lys Arg Ala Val Asp Phe Glu Thr Gly Gly Gly Glu Ser Ser Lys Gln
                  85                  90                  95

 tat gct ttt ctg tgt agt gaa gaa cga atg tca gag gtt ttc aag gat      336
 Tyr Ala Phe Leu Cys Ser Glu Glu Arg Met Ser Glu Val Phe Lys Asp
             100                 105                 110

 gag ctg atg aac ctg ata tac cga act cct gtg aca caa aag gct ctc      384
 Glu Leu Met Asn Leu Ile Tyr Arg Thr Pro Val Thr Gln Lys Ala Leu
         115                 120                 125

 act gtg gag agg ttt ttc cca gtc ctc ctc tcc act cct gaa acc gtc      432
 Thr Val Glu Arg Phe Phe Pro Val Leu Leu Ser Thr Pro Glu Thr Val
     130                 135                 140

 ctc act tgc ttt cat tcc tta caa gta gcg ggt cag cag gca gac agt      480
 Leu Thr Cys Phe His Ser Leu Gln Val Ala Gly Gln Gln Ala Asp Ser
 145                 150                 155                 160

 tcc tca gcg gct gta agc tcc ctg ttt caa aca gtc aaa gct aaa aat      528
 Ser Ser Ala Ala Val Ser Ser Leu Phe Gln Thr Val Lys Ala Lys Asn
                 165                 170                 175

 gtg gca gct ggc cct aga gaa gta gct atc ctg ctc agg ata atc ccc      576
 Val Ala Ala Gly Pro Arg Glu Val Ala Ile Leu Leu Arg Ile Ile Pro
             180                 185                 190

 tgg aca aca gcc agc tcc ttt gat ttt gtg cca ttt agt cct tcc ctt      624
 Trp Thr Thr Ala Ser Ser Phe Asp Phe Val Pro Phe Ser Pro Ser Leu
         195                 200                 205

 cat ctg ctg acg ctg ata ctt tcg ggt gag gtg gaa gga gag agc ata      672
 His Leu Leu Thr Leu Ile Leu Ser Gly Glu Val Glu Gly Glu Ser Ile
     210                 215                 220

 cct gtt ggt gag ctg gct gtg gta tct ggg acc cag tgg cag gtc acc      720
 Pro Val Gly Glu Leu Ala Val Val Ser Gly Thr Gln Trp Gln Val Thr
 225                 230                 235                 240

 acc gta tgg ggc tgc cag ttg ctc ccc cac ccc att cct cta aga gct      768
 Thr Val Trp Gly Cys Gln Leu Leu Pro His Pro Ile Pro Leu Arg Ala
                 245                 250                 255

 agt agg gag aga gaa ccc gga aga gca gca cgg ctt gct gaa act tct      816
 Ser Arg Glu Arg Glu Pro Gly Arg Ala Ala Arg Leu Ala Glu Thr Ser
             260                 265                 270

 ctg aga ccc cag caa gag tcc ttt tac agt ttc ccc gaa acc gtc aca      864
 Leu Arg Pro Gln Gln Glu Ser Phe Tyr Ser Phe Pro Glu Thr Val Thr
         275                 280                 285

 agt ttt cct gac cgc ctg ctg ggg gct ttc tgt tgc aga cct acg cgg      912
 Ser Phe Pro Asp Arg Leu Leu Gly Ala Phe Cys Cys Arg Pro Thr Arg
     290                 295                 300

 cag ctg cct gcc agc cct gcc aga ttt gac ttc atc ttg gct gcc gcc      960
 Gln Leu Pro Ala Ser Pro Ala Arg Phe Asp Phe Ile Leu Ala Ala Ala
 305                 310                 315                 320

 ttt tca ctg act gga gga ctt tcc aga cga aat ctg gca ctt ctc agt     1008
 Phe Ser Leu Thr Gly Gly Leu Ser Arg Arg Asn Leu Ala Leu Leu Ser
                 325                 330                 335

 aac ctt gaa ctt gaa cat tca gtg aca gaa ggg aaa ggg aga ggg ttt     1056
 Asn Leu Glu Leu Glu His Ser Val Thr Glu Gly Lys Gly Arg Gly Phe
             340                 345                 350

 cag ctg ctg gag ctg ggt aac tgt gca ggg ctc tcg cag cgg gcc att     1104
 Gln Leu Leu Glu Leu Gly Asn Cys Ala Gly Leu Ser Gln Arg Ala Ile
         355                 360                 365

 tgt ggc tct gag ggt gcc aag ctg cag tgt tct gag gga gcg gag gcc     1152
 Cys Gly Ser Glu Gly Ala Lys Leu Gln Cys Ser Glu Gly Ala Glu Ala
     370                 375                 380

 cct ggt gct cag gag ttc ttt ggc tgt gtc cgg atc cac caa ttc ccc     1200
 Pro Gly Ala Gln Glu Phe Phe Gly Cys Val Arg Ile His Gln Phe Pro
 385                 390                 395                 400

 gct tcc cta agg atg acg ggt aaa tct ggt gag acc cgc tgc cct cct     1248
 Ala Ser Leu Arg Met Thr Gly Lys Ser Gly Glu Thr Arg Cys Pro Pro
                 405                 410                 415

 aat gtt gga gga aag ctg gag ccc ctc agt caa cat tta tgg aag gga     1296
 Asn Val Gly Gly Lys Leu Glu Pro Leu Ser Gln His Leu Trp Lys Gly
             420                 425                 430

 ttt aat gca tca tgg gct gtg aag ttc tct gct tgg aca ctt cac tcc     1344
 Phe Asn Ala Ser Trp Ala Val Lys Phe Ser Ala Trp Thr Leu His Ser
         435                 440                 445

 gtg ctg tca gca ccc ttt gct tct gtt cct gca ctt gtg cca aac cct     1392
 Val Leu Ser Ala Pro Phe Ala Ser Val Pro Ala Leu Val Pro Asn Pro
     450                 455                 460

 ttg gat gaa gag cct cgt tgt gcc cat ctc tgg att cct agt gcc aag     1440
 Leu Asp Glu Glu Pro Arg Cys Ala His Leu Trp Ile Pro Ser Ala Lys
 465                 470                 475                 480

 cat ggg gtc cag cac ttg aca cat ggc tgt tgc tga                     1476
 His Gly Val Gln His Leu Thr His Gly Cys Cys 
                 485                 490





      <210> 718
      <211> 447
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(447)

      <400> 718
  atg att ctg ggg tcc ctg gcg ttc tac ctg gtg cag ctc aca ggt tcc      48
  Met Ile Leu Gly Ser Leu Ala Phe Tyr Leu Val Gln Leu Thr Gly Ser
    1               5                  10                  15

 gag aca ggc cag gcc tcc cgt ctc cgc tcc agc ccc cag gct cga cag       96
 Glu Thr Gly Gln Ala Ser Arg Leu Arg Ser Ser Pro Gln Ala Arg Gln
              20                  25                  30

 agt ggg aag gat gaa aca cac tcg gac cct act ggc agg gag gcc tgc      144
 Ser Gly Lys Asp Glu Thr His Ser Asp Pro Thr Gly Arg Glu Ala Cys
          35                  40                  45

 gag gct gac tcc aca tgg gct cac cct gac cag gtc acg gga agg gga      192
 Glu Ala Asp Ser Thr Trp Ala His Pro Asp Gln Val Thr Gly Arg Gly
      50                  55                  60

 ctg ggg gag tca ggc cac ccc agt gga ctc cag ctc cca gag gtg gaa      240
 Leu Gly Glu Ser Gly His Pro Ser Gly Leu Gln Leu Pro Glu Val Glu
  65                  70                  75                  80

 ggc gac cag gct gtg ccg act acg ttc cgg act tca gca ggt caa ggg      288
 Gly Asp Gln Ala Val Pro Thr Thr Phe Arg Thr Ser Ala Gly Gln Gly
                  85                  90                  95

 agc gct cct gca ccc aga acc ttg gga cct ctt tca caa gca cgg gag      336
 Ser Ala Pro Ala Pro Arg Thr Leu Gly Pro Leu Ser Gln Ala Arg Glu
             100                 105                 110

 aaa caa gag tgc aaa acc tgg gtg ctg cct gga gcc tcc ttc acc tgg      384
 Lys Gln Glu Cys Lys Thr Trp Val Leu Pro Gly Ala Ser Phe Thr Trp
         115                 120                 125

 cac agg aaa gcc ctt gaa aga agc gag gaa aag acc acg aat ctg ctt      432
 His Arg Lys Ala Leu Glu Arg Ser Glu Glu Lys Thr Thr Asn Leu Leu
     130                 135                 140

 gga cag aag aag tga                                                  447
 Gly Gln Lys Lys 
 145





      <210> 719
      <211> 588
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(588)

      <400> 719
  atg cgg gtg aag cgg ctt ctg aag gcg ggt gtc atc tct gcc ctg gct      48
  Met Arg Val Lys Arg Leu Leu Lys Ala Gly Val Ile Ser Ala Leu Ala
    1               5                  10                  15

 tgc atg gtg aaa gca gat agt gcc atc ctc act gac cag acc aag gag       96
 Cys Met Val Lys Ala Asp Ser Ala Ile Leu Thr Asp Gln Thr Lys Glu
              20                  25                  30

 ctg ctg gcc agg gta ttc ctg gca ctg tgt gac aac cca aag gac cga      144
 Leu Leu Ala Arg Val Phe Leu Ala Leu Cys Asp Asn Pro Lys Asp Arg
          35                  40                  45

 ggc acc att gtg gct caa ggt ggt ggc aag gcc ctg att ccc ctg gct      192
 Gly Thr Ile Val Ala Gln Gly Gly Gly Lys Ala Leu Ile Pro Leu Ala
      50                  55                  60

 ttg gag ggc aca gat gtg ggc aag gtg aag gca gcc cac gct cta gca      240
 Leu Glu Gly Thr Asp Val Gly Lys Val Lys Ala Ala His Ala Leu Ala
  65                  70                  75                  80

 aag atc gct gct gtc tcc aat ccg gac att gct ttt cct ggg gag cgg      288
 Lys Ile Ala Ala Val Ser Asn Pro Asp Ile Ala Phe Pro Gly Glu Arg
                  85                  90                  95

 gtg tat gag gtg gtg cgg ccc ctt gta aga ctc ttg gac aca cag agg      336
 Val Tyr Glu Val Val Arg Pro Leu Val Arg Leu Leu Asp Thr Gln Arg
             100                 105                 110

 gat ggg ctt cag aac tat gag gct ctc cta ggc ctc acc aac ctg tct      384
 Asp Gly Leu Gln Asn Tyr Glu Ala Leu Leu Gly Leu Thr Asn Leu Ser
         115                 120                 125

 ggg cgg agt gac aaa ctc cgg cag aag atc ttt aag gag agg gcc ttg      432
 Gly Arg Ser Asp Lys Leu Arg Gln Lys Ile Phe Lys Glu Arg Ala Leu
     130                 135                 140

 cca gac atc gag aac tac atg ttt gag aat cat gat cag ctg cgg cag      480
 Pro Asp Ile Glu Asn Tyr Met Phe Glu Asn His Asp Gln Leu Arg Gln
 145                 150                 155                 160

 gcg gcc acc gag tgc atg tgc aac atg gtg ctc cac aag gag gaa aaa      528
 Ala Ala Thr Glu Cys Met Cys Asn Met Val Leu His Lys Glu Glu Lys
                 165                 170                 175

 gca ttc att tca atg tca tca gaa cag cac aac tta gag tta aac aag      576
 Ala Phe Ile Ser Met Ser Ser Glu Gln His Asn Leu Glu Leu Asn Lys
             180                 185                 190

 cct tca gga tga                                                      588
 Pro Ser Gly 
         195





      <210> 720
      <211> 345
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(345)

      <400> 720
  atg ggc att atg ttg tgc ctg cca gcc ctc cta tct gaa tta tct gca      48
  Met Gly Ile Met Leu Cys Leu Pro Ala Leu Leu Ser Glu Leu Ser Ala
    1               5                  10                  15

 tgt tac gct gga gaa ggt gct gta tgt cag ttt gcc cct cag aat gct       96
 Cys Tyr Ala Gly Glu Gly Ala Val Cys Gln Phe Ala Pro Gln Asn Ala
              20                  25                  30

 tcc caa aag ccc ttt caa gac cct ttt att gtc agg gca gag aac ttg      144
 Ser Gln Lys Pro Phe Gln Asp Pro Phe Ile Val Arg Ala Glu Asn Leu
          35                  40                  45

 cct cat cgc tcc agg cat gtg aat ttg tac tta gca cat cca gac ggg      192
 Pro His Arg Ser Arg His Val Asn Leu Tyr Leu Ala His Pro Asp Gly
      50                  55                  60

 cat ggg ata tcc atg ttc tac agc acc ttc tct ctg gag cac tgt gaa      240
 His Gly Ile Ser Met Phe Tyr Ser Thr Phe Ser Leu Glu His Cys Glu
  65                  70                  75                  80

 ggg caa gct cag cag atg gct cat cag ttt gac cag gac aga gaa ttg      288
 Gly Gln Ala Gln Gln Met Ala His Gln Phe Asp Gln Asp Arg Glu Leu
                  85                  90                  95

 tat gga gaa ttc aag cca aag gaa agc cta ctc aac agg ctg aca tat      336
 Tyr Gly Glu Phe Lys Pro Lys Glu Ser Leu Leu Asn Arg Leu Thr Tyr
             100                 105                 110

 cct gac tga                                                          345
 Pro Asp 






      <210> 721
      <211> 399
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(399)

      <400> 721
  atg gcc ccg tcg agg cgg cca acc gga tgt gcc ctc ctg cag gcc tgg      48
  Met Ala Pro Ser Arg Arg Pro Thr Gly Cys Ala Leu Leu Gln Ala Trp
    1               5                  10                  15

 ggc ctc atc ctc acc agc cct cgg caa cag cag ccg ttc att ttt cca       96
 Gly Leu Ile Leu Thr Ser Pro Arg Gln Gln Gln Pro Phe Ile Phe Pro
              20                  25                  30

 acg aag ggg agg gaa aac aag cgc tgg aag tca aga act ttc tca aca      144
 Thr Lys Gly Arg Glu Asn Lys Arg Trp Lys Ser Arg Thr Phe Ser Thr
          35                  40                  45

 ctg gag ccc agt gcc caa atc cat ggc tgg cag gag ctg gac ttc agt      192
 Leu Glu Pro Ser Ala Gln Ile His Gly Trp Gln Glu Leu Asp Phe Ser
      50                  55                  60

 ggc cag tgg ctg aaa gac ctg cag gcc act ctt gag aaa ggg cat gaa      240
 Gly Gln Trp Leu Lys Asp Leu Gln Ala Thr Leu Glu Lys Gly His Glu
  65                  70                  75                  80

 gtg gcc tca gac acc tcc agt atc tcc tgt tca tgg ggg tcc ctg ctc      288
 Val Ala Ser Asp Thr Ser Ser Ile Ser Cys Ser Trp Gly Ser Leu Leu
                  85                  90                  95

 tcc caa atg gtt cag atg ctt caa agt tta acc agt aga cat aag agg      336
 Ser Gln Met Val Gln Met Leu Gln Ser Leu Thr Ser Arg His Lys Arg
             100                 105                 110

 aat gtt ctg gaa gcc att cag cac tgt cca caa tgt cgc agg atg agc      384
 Asn Val Leu Glu Ala Ile Gln His Cys Pro Gln Cys Arg Arg Met Ser
         115                 120                 125

 aga tct gtc tgc tag                                                  399
 Arg Ser Val Cys 
     130





      <210> 722
      <211> 351
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(351)

      <400> 722
  atg aca gcc tgc tgg cag ccc tcg ctc act ctt ggc gcc tcc tcg gcc      48
  Met Thr Ala Cys Trp Gln Pro Ser Leu Thr Leu Gly Ala Ser Ser Ala
    1               5                  10                  15

 ttg gcg ccc act ctg gcc acg ctt gag gag ccc ttc agc cca cca ctg       96
 Leu Ala Pro Thr Leu Ala Thr Leu Glu Glu Pro Phe Ser Pro Pro Leu
              20                  25                  30

 cac tgt ggg agc ccc ttt ctg ggc tgg cca agg ccg gag ccg gct ccc      144
 His Cys Gly Ser Pro Phe Leu Gly Trp Pro Arg Pro Glu Pro Ala Pro
          35                  40                  45

 tca gct tgc ggg gag gtg tgg agg gag agg cgg gag cgg gaa ccg ggg      192
 Ser Ala Cys Gly Glu Val Trp Arg Glu Arg Arg Glu Arg Glu Pro Gly
      50                  55                  60

 ctg tgc gcg gcg ctt gct ggc cag cat aca aca gga act tcc cct gga      240
 Leu Cys Ala Ala Leu Ala Gly Gln His Thr Thr Gly Thr Ser Pro Gly
  65                  70                  75                  80

 gag ctt cgt cac agt aac act cca cta gca gaa acg ccc acc att ctg      288
 Glu Leu Arg His Ser Asn Thr Pro Leu Ala Glu Thr Pro Thr Ile Leu
                  85                  90                  95

 agc ctc acg gaa act gag aaa gac ctg aag gat agt tcc cac ctt gtt      336
 Ser Leu Thr Glu Thr Glu Lys Asp Leu Lys Asp Ser Ser His Leu Val
             100                 105                 110

 gct gtg aaa ggc taa                                                  351
 Ala Val Lys Gly 
         115





      <210> 723
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 723
  atg agc tgg ctg aga gct gac atg agg atg agg atg gcc ctg cct ttg      48
  Met Ser Trp Leu Arg Ala Asp Met Arg Met Arg Met Ala Leu Pro Leu
    1               5                  10                  15

 ctg gta ggt ata gcg cat gca gcc att gct gta gac gta gac ttt act       96
 Leu Val Gly Ile Ala His Ala Ala Ile Ala Val Asp Val Asp Phe Thr
              20                  25                  30

 aga agg gaa gcc att gcc aaa gaa cat gtt gaa gag gtc ttc agg gga      144
 Arg Arg Glu Ala Ile Ala Lys Glu His Val Glu Glu Val Phe Arg Gly
          35                  40                  45

 gat gtc agc ctc aaa gcc gtg gtg gaa atc ccc atg acg atg ctg gac      192
 Asp Val Ser Leu Lys Ala Val Val Glu Ile Pro Met Thr Met Leu Asp
      50                  55                  60

 ctg act gcc tga                                                      204
 Leu Thr Ala 
  65





      <210> 724
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 724
  atg gtt ggc aac gtc tcc ctc cta atg cat tcc ttc ttc tac ctg atc      48
  Met Val Gly Asn Val Ser Leu Leu Met His Ser Phe Phe Tyr Leu Ile
    1               5                  10                  15

 ttt caa ttt gga gat ttc cca ggc ctt gat cct agg tcc tct ttt cac       96
 Phe Gln Phe Gly Asp Phe Pro Gly Leu Asp Pro Arg Ser Ser Phe His
              20                  25                  30

 tgc tgt gag gca ttc aca cac acc tat gac ttc agt tac cat gtg gaa      144
 Cys Cys Glu Ala Phe Thr His Thr Tyr Asp Phe Ser Tyr His Val Glu
          35                  40                  45

 gtg gac tgt tac agt gat gat agc ttt atg gag tat ttg ctt tta ttg      192
 Val Asp Cys Tyr Ser Asp Asp Ser Phe Met Glu Tyr Leu Leu Leu Leu
      50                  55                  60

 aat tat atc acc aag ata aat atc cag aag tgg aaa tac ttc gac aga      240
 Asn Tyr Ile Thr Lys Ile Asn Ile Gln Lys Trp Lys Tyr Phe Asp Arg
  65                  70                  75                  80

 gag tat gaa atg gct ctt act aca tat tac tgt att gtt ttt ctg aag      288
 Glu Tyr Glu Met Ala Leu Thr Thr Tyr Tyr Cys Ile Val Phe Leu Lys
                  85                  90                  95

 ggc tat atc att tta gga ttg agc aag ttt taa                          321
 Gly Tyr Ile Ile Leu Gly Leu Ser Lys Phe 
             100                 105





      <210> 725
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 725
  atg gca gaa ctg ggc tac aga ctc aga gca ggg tcc ccc ctg ctc acc      48
  Met Ala Glu Leu Gly Tyr Arg Leu Arg Ala Gly Ser Pro Leu Leu Thr
    1               5                  10                  15

 gtc ctg gcc gtc aca atg ttc acg tct ggg gat atc cct ttt gtg acg       96
 Val Leu Ala Val Thr Met Phe Thr Ser Gly Asp Ile Pro Phe Val Thr
              20                  25                  30

 cag aat ctt gca gcg aaa cag ttg ggt gta gcc tcc tgt gag aaa gaa      144
 Gln Asn Leu Ala Ala Lys Gln Leu Gly Val Ala Ser Cys Glu Lys Glu
          35                  40                  45

 atg ctt gca gca ggg att ttc cag gcc ggc atc tca att gca cag aaa      192
 Met Leu Ala Ala Gly Ile Phe Gln Ala Gly Ile Ser Ile Ala Gln Lys
      50                  55                  60

 aac att ttg gga atg ttt cca tca gcc cgg cag tct gaa ggt ttg agc      240
 Asn Ile Leu Gly Met Phe Pro Ser Ala Arg Gln Ser Glu Gly Leu Ser
  65                  70                  75                  80

 gga atg gcc tgg tgt cca gag aaa cga agc tgc gcc agc tgc ccc cac      288
 Gly Met Ala Trp Cys Pro Glu Lys Arg Ser Cys Ala Ser Cys Pro His
                  85                  90                  95

 ccc agt ccc acg ctc cct cca gaa gct tcc ctc acg gcg ctc aac gcc      336
 Pro Ser Pro Thr Leu Pro Pro Glu Ala Ser Leu Thr Ala Leu Asn Ala
             100                 105                 110

 cag tgc ggt tat cgc ctg ccg tgc gcc ttt gaa ccc cag gag gcc ggg      384
 Gln Cys Gly Tyr Arg Leu Pro Cys Ala Phe Glu Pro Gln Glu Ala Gly
         115                 120                 125

 gag tat gga atg tgc gat gcc tga                                      408
 Glu Tyr Gly Met Cys Asp Ala 
     130                 135





      <210> 726
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 726
  atg gaa cag tgc ctg gca ctt agg aag cct tca gga aat gct atc tct      48
  Met Glu Gln Cys Leu Ala Leu Arg Lys Pro Ser Gly Asn Ala Ile Ser
    1               5                  10                  15

 tcc ctg ttg ata atc ttg acc cgt aca ctg cct ttg gtt gcc att cat       96
 Ser Leu Leu Ile Ile Leu Thr Arg Thr Leu Pro Leu Val Ala Ile His
              20                  25                  30

 aaa cct gcc acc aat agt aac aaa gtg ctg gat gca cct ttt gtg ctt      144
 Lys Pro Ala Thr Asn Ser Asn Lys Val Leu Asp Ala Pro Phe Val Leu
          35                  40                  45

 atc ttt gtg cta aat gtg ccc gag gga cac cta tgg aag aag atg cag      192
 Ile Phe Val Leu Asn Val Pro Glu Gly His Leu Trp Lys Lys Met Gln
      50                  55                  60

 gtc ttt aag agc cat cag ctc cag att atg gcc acc cca tgt cca gca      240
 Val Phe Lys Ser His Gln Leu Gln Ile Met Ala Thr Pro Cys Pro Ala
  65                  70                  75                  80

 ctt aga atg gag gcc aaa acc att ccc tcg gaa att gtg ttt cct tgc      288
 Leu Arg Met Glu Ala Lys Thr Ile Pro Ser Glu Ile Val Phe Pro Cys
                  85                  90                  95

 caa gat ggg gac tgc gtg gtt gcc ctt ttt tga                          321
 Gln Asp Gly Asp Cys Val Val Ala Leu Phe 
             100                 105





      <210> 727
      <211> 615
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(615)

      <400> 727
  atg ctg ctt atc tta atg ctt tca ctg tcc ttc aat gag cag cct gtc      48
  Met Leu Leu Ile Leu Met Leu Ser Leu Ser Phe Asn Glu Gln Pro Val
    1               5                  10                  15

 ctc cct tcc aca cat cag gct gac agc acc aaa cac ggc cga ggc ctc       96
 Leu Pro Ser Thr His Gln Ala Asp Ser Thr Lys His Gly Arg Gly Leu
              20                  25                  30

 agc cct gag tct ccc cgc tgc aga gtg ccc aag cct gag ttc cag cag      144
 Ser Pro Glu Ser Pro Arg Cys Arg Val Pro Lys Pro Glu Phe Gln Gln
          35                  40                  45

 gtt ctt cag ggg ccg ctg acc agg gaa cac tgc gcg tgg gga gag aaa      192
 Val Leu Gln Gly Pro Leu Thr Arg Glu His Cys Ala Trp Gly Glu Lys
      50                  55                  60

 ggt cgc aga gcg ggg gct gtg gaa ggc att cgc aga gga aat ggc agc      240
 Gly Arg Arg Ala Gly Ala Val Glu Gly Ile Arg Arg Gly Asn Gly Ser
  65                  70                  75                  80

 atc cct cag cag cag ggg gcc cgt ccg tct gta agg act cac cct tcc      288
 Ile Pro Gln Gln Gln Gly Ala Arg Pro Ser Val Arg Thr His Pro Ser
                  85                  90                  95

 tct ggg atc ctg ctc ttc ctc tct ggt cag tcc ctg ggc tgc tgc ccg      336
 Ser Gly Ile Leu Leu Phe Leu Ser Gly Gln Ser Leu Gly Cys Cys Pro
             100                 105                 110

 acc cgc atg gag aga atc cac gcc ccc atg gtt ctg agc aca ggc tgg      384
 Thr Arg Met Glu Arg Ile His Ala Pro Met Val Leu Ser Thr Gly Trp
         115                 120                 125

 tgt ctc gcc agg tac aca gca gat ctt ctg gag gtg ctg aag acc aat      432
 Cys Leu Ala Arg Tyr Thr Ala Asp Leu Leu Glu Val Leu Lys Thr Asn
     130                 135                 140

 tac ggc atc ccc tcc gcc tgc ttc tct cag cct ccc aca gca gcc caa      480
 Tyr Gly Ile Pro Ser Ala Cys Phe Ser Gln Pro Pro Thr Ala Ala Gln
 145                 150                 155                 160

 ctc ctg aga gac ccc aga gcc atc tgg gga ccc aag atg gtg ccc aag      528
 Leu Leu Arg Asp Pro Arg Ala Ile Trp Gly Pro Lys Met Val Pro Lys
                 165                 170                 175

 tgg tcc aag ccc cat cgg gtc tcc tgg agg gct gca cgg cat ccg ccc      576
 Trp Ser Lys Pro His Arg Val Ser Trp Arg Ala Ala Arg His Pro Pro
             180                 185                 190

 tgg acc cat gtc act cta gag ggt ggt tac ggt gag tga                  615
 Trp Thr His Val Thr Leu Glu Gly Gly Tyr Gly Glu 
         195                 200





      <210> 728
      <211> 729
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(729)

      <400> 728
  atg agt tct gtt ctt tcc gcc ttc agt ggt tta ctc acc tgc ggt atg      48
  Met Ser Ser Val Leu Ser Ala Phe Ser Gly Leu Leu Thr Cys Gly Met
    1               5                  10                  15

 gtg gag tat ctg ttt gtc tgt tcc ctc tcg tgc tct tat tat ttg cag       96
 Val Glu Tyr Leu Phe Val Cys Ser Leu Ser Cys Ser Tyr Tyr Leu Gln
              20                  25                  30

 tat gtg aag ggg atg cca gcc cct gcc atg ccc ctc cca gcc atg acc      144
 Tyr Val Lys Gly Met Pro Ala Pro Ala Met Pro Leu Pro Ala Met Thr
          35                  40                  45

 ccc cag tgc tct aag gac aag gcc ctg ttg tgc cca tgt gcc atc tgc      192
 Pro Gln Cys Ser Lys Asp Lys Ala Leu Leu Cys Pro Cys Ala Ile Cys
      50                  55                  60

 cct tct cct gcc ctg gtc cat ggt gtc tat gac tgc tct gtg acc cct      240
 Pro Ser Pro Ala Leu Val His Gly Val Tyr Asp Cys Ser Val Thr Pro
  65                  70                  75                  80

 gcc ccc acc agc tct gcc tgc cgc aga ggg aca gca gcc ctt gtg caa      288
 Ala Pro Thr Ser Ser Ala Cys Arg Arg Gly Thr Ala Ala Leu Val Gln
                  85                  90                  95

 gct ggc ttc agc cgt ttc agg acc cag att cta tcc atc tct ttc aag      336
 Ala Gly Phe Ser Arg Phe Arg Thr Gln Ile Leu Ser Ile Ser Phe Lys
             100                 105                 110

 caa cca gag cag aac ctc gaa ttg ggg aag gtg aag gaa ggg aca cag      384
 Gln Pro Glu Gln Asn Leu Glu Leu Gly Lys Val Lys Glu Gly Thr Gln
         115                 120                 125

 cac act aca gcc cct gtt gct agg ttc acc ctt ggg aaa gca ggc tgg      432
 His Thr Thr Ala Pro Val Ala Arg Phe Thr Leu Gly Lys Ala Gly Trp
     130                 135                 140

 tgg ctt cca gac acg gct tcc tca cat tac ttc cag aaa tgt cct gag      480
 Trp Leu Pro Asp Thr Ala Ser Ser His Tyr Phe Gln Lys Cys Pro Glu
 145                 150                 155                 160

 aat aac tct atc cat gtt acc caa tgt gcc aag cat agg tac atc cta      528
 Asn Asn Ser Ile His Val Thr Gln Cys Ala Lys His Arg Tyr Ile Leu
                 165                 170                 175

 cct ctc tat tgc cct ggt agc ctc ccc aag gtc aga gct ggc tct gtc      576
 Pro Leu Tyr Cys Pro Gly Ser Leu Pro Lys Val Arg Ala Gly Ser Val
             180                 185                 190

 cat ccc tct tct gtg tat tct atc cca ccc ctg cct gcc tac cac atc      624
 His Pro Ser Ser Val Tyr Ser Ile Pro Pro Leu Pro Ala Tyr His Ile
         195                 200                 205

 aag ctg gca gaa tca aac aag ggt gtg gcc cct gga acc aga cag cct      672
 Lys Leu Ala Glu Ser Asn Lys Gly Val Ala Pro Gly Thr Arg Gln Pro
     210                 215                 220

 ggg ctg gga tct ggc tgt atc cgg gct ggg atc tgg ctg tat cat aca      720
 Gly Leu Gly Ser Gly Cys Ile Arg Ala Gly Ile Trp Leu Tyr His Thr
 225                 230                 235                 240

 ctg gcc tag                                                          729
 Leu Ala 






      <210> 729
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 729
  atg agc cac cgc acc cgg ctt act ggg ggc ttt tta acc ttg ttt ggc      48
  Met Ser His Arg Thr Arg Leu Thr Gly Gly Phe Leu Thr Leu Phe Gly
    1               5                  10                  15

 tac att acc tca gtg aac aag ggg aag ctc aca aca gga act cac aca       96
 Tyr Ile Thr Ser Val Asn Lys Gly Lys Leu Thr Thr Gly Thr His Thr
              20                  25                  30

 aag aag gaa gag aac agt acc aac aag atg ggg gaa gtc aac agt gaa      144
 Lys Lys Glu Glu Asn Ser Thr Asn Lys Met Gly Glu Val Asn Ser Glu
          35                  40                  45

 gtg ttt ctc agc atc ata aag gca gaa gct gtg gtt cct gtg ggg cct      192
 Val Phe Leu Ser Ile Ile Lys Ala Glu Ala Val Val Pro Val Gly Pro
      50                  55                  60

 gcc aac cgt tcc cag atg ctg aac tct gct ggg agt ttt ttc cat ggg      240
 Ala Asn Arg Ser Gln Met Leu Asn Ser Ala Gly Ser Phe Phe His Gly
  65                  70                  75                  80

 act tta aaa aat gat gcc ctt agg ttg ggc cag acc tct gtt aac ttc      288
 Thr Leu Lys Asn Asp Ala Leu Arg Leu Gly Gln Thr Ser Val Asn Phe
                  85                  90                  95

 agt agg gat ggc acc agg ttc aag agg cca aag aag aga cct gga gct      336
 Ser Arg Asp Gly Thr Arg Phe Lys Arg Pro Lys Lys Arg Pro Gly Ala
             100                 105                 110

 agt gaa gga aac ata ggg ttt att tgg gga atc tta cag ggt ggt cca      384
 Ser Glu Gly Asn Ile Gly Phe Ile Trp Gly Ile Leu Gln Gly Gly Pro
         115                 120                 125

 gtg gcc gcg ggc tgg aca gaa ctg caa cca ctt ata aaa agc atg cag      432
 Val Ala Ala Gly Trp Thr Glu Leu Gln Pro Leu Ile Lys Ser Met Gln
     130                 135                 140

 ttt aca tag                                                          441
 Phe Thr 
 145





      <210> 730
      <211> 138
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(138)

      <400> 730
  atg ctg cca ttc acg gct gtg ctg tca gct gcc tgg atg gag gtg gag      48
  Met Leu Pro Phe Thr Ala Val Leu Ser Ala Ala Trp Met Glu Val Glu
    1               5                  10                  15

 cca gtt tcc tac gga cag gaa gca cac atc atc aag tca gtc tgc ctg       96
 Pro Val Ser Tyr Gly Gln Glu Ala His Ile Ile Lys Ser Val Cys Leu
              20                  25                  30

 cag ttt aag gcc cca gga ctt gga gac tac ctc ttg gag tga              138
 Gln Phe Lys Ala Pro Gly Leu Gly Asp Tyr Leu Leu Glu 
          35                  40                  45





      <210> 731
      <211> 222
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(222)

      <400> 731
  atg ctc aag caa gtg gtg ggc ctg gag ggt cta ctg tgt gtc ttc aca      48
  Met Leu Lys Gln Val Val Gly Leu Glu Gly Leu Leu Cys Val Phe Thr
    1               5                  10                  15

 gtg gtc aag tgc agc aac cac tta gct ccc aag gca tgt gcc tca gct       96
 Val Val Lys Cys Ser Asn His Leu Ala Pro Lys Ala Cys Ala Ser Ala
              20                  25                  30

 ggc att tcg tca caa tca aca ctc tgt ggc cct gtg gtt gga gac cgc      144
 Gly Ile Ser Ser Gln Ser Thr Leu Cys Gly Pro Val Val Gly Asp Arg
          35                  40                  45

 tgc tca agt gca ttc gaa agg atc cat ccc atg cca ttc ttc aga gtc      192
 Cys Ser Ser Ala Phe Glu Arg Ile His Pro Met Pro Phe Phe Arg Val
      50                  55                  60

 atc ttt act gct gca gtg gtc aac ttg tag                              222
 Ile Phe Thr Ala Ala Val Val Asn Leu 
  65                  70





      <210> 732
      <211> 171
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(171)

      <400> 732
  atg aag ctg cgg acc ctc ctg gac ctc tcc ctt ctc atc ctt tcc gtg      48
  Met Lys Leu Arg Thr Leu Leu Asp Leu Ser Leu Leu Ile Leu Ser Val
    1               5                  10                  15

 atc agc cct gga aaa cct tcc aaa gaa ctg tcc tcc ttc tcc cgg gat       96
 Ile Ser Pro Gly Lys Pro Ser Lys Glu Leu Ser Ser Phe Ser Arg Asp
              20                  25                  30

 ctc aga gaa aat tcg cct gag ttc agt gtc cac gtg acc caa gct ctg      144
 Leu Arg Glu Asn Ser Pro Glu Phe Ser Val His Val Thr Gln Ala Leu
          35                  40                  45

 aat gcg gta acg tgc acg gag aga taa                                  171
 Asn Ala Val Thr Cys Thr Glu Arg 
      50                  55





      <210> 733
      <211> 333
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(333)

      <400> 733
  atg tat atg ctg ctc caa gca ttt tgg ttg tgg cag gaa act ttg aag      48
  Met Tyr Met Leu Leu Gln Ala Phe Trp Leu Trp Gln Glu Thr Leu Lys
    1               5                  10                  15

 act att ttg ctg tac aaa ttc aca aag ccc cct gca aac act ccc gtg       96
 Thr Ile Leu Leu Tyr Lys Phe Thr Lys Pro Pro Ala Asn Thr Pro Val
              20                  25                  30

 ctt ggg gtg aat gcc caa gtg tgt cac agc tgc ctt gca gct ctg agg      144
 Leu Gly Val Asn Ala Gln Val Cys His Ser Cys Leu Ala Ala Leu Arg
          35                  40                  45

 atc aga aag gtt aat gga cat aaa aga aac ttc aaa gct caa cct cct      192
 Ile Arg Lys Val Asn Gly His Lys Arg Asn Phe Lys Ala Gln Pro Pro
      50                  55                  60

 aat ggg aag ctg ccc ttg gtt tta ggc tgt ctt tgc tta ctg acc gac      240
 Asn Gly Lys Leu Pro Leu Val Leu Gly Cys Leu Cys Leu Leu Thr Asp
  65                  70                  75                  80

 tta att cat gct ttg ggt tat gac tgt agg aga gat ttt cct gtg tct      288
 Leu Ile His Ala Leu Gly Tyr Asp Cys Arg Arg Asp Phe Pro Val Ser
                  85                  90                  95

 ttg gag tat gct gaa ctt gtg ttt ctt ttt gtt gtt gca tat tag          333
 Leu Glu Tyr Ala Glu Leu Val Phe Leu Phe Val Val Ala Tyr 
             100                 105                 110





      <210> 734
      <211> 231
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(231)

      <400> 734
  atg ctg cat ctg ctc ggc atg gcc acc tgg ctt ctg cct gcg gtc atc      48
  Met Leu His Leu Leu Gly Met Ala Thr Trp Leu Leu Pro Ala Val Ile
    1               5                  10                  15

 aaa acc aga atc tcc cag tgg agg cct att gtg ggc agg ccc aga aag       96
 Lys Thr Arg Ile Ser Gln Trp Arg Pro Ile Val Gly Arg Pro Arg Lys
              20                  25                  30

 gca gga gaa aca gaa gag gaa ggg gtg agg ggc cta gaa cga caa cct      144
 Ala Gly Glu Thr Glu Glu Glu Gly Val Arg Gly Leu Glu Arg Gln Pro
          35                  40                  45

 cag ggt gaa gag gtg aga caa gaa gaa agg caa atg gca gtg cac gtt      192
 Gln Gly Glu Glu Val Arg Gln Glu Glu Arg Gln Met Ala Val His Val
      50                  55                  60

 tcc cat gac agt caa ggc cct ggt gtt ggg aaa cac tga                  231
 Ser His Asp Ser Gln Gly Pro Gly Val Gly Lys His 
  65                  70                  75





      <210> 735
      <211> 693
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(693)

      <400> 735
  atg cct ggg agt cgc ctg tcc cat aca cct tcc tac ctg atc ctc ttg      48
  Met Pro Gly Ser Arg Leu Ser His Thr Pro Ser Tyr Leu Ile Leu Leu
    1               5                  10                  15

 ctg ccg cca ccg ccg ctg ctg cca ctg gtc cat aag ccg ctg ctg gga       96
 Leu Pro Pro Pro Pro Leu Leu Pro Leu Val His Lys Pro Leu Leu Gly
              20                  25                  30

 agc ctg gca gca tct aga ttt ctg aag atg agg gtc ttg gca gaa att      144
 Ser Leu Ala Ala Ser Arg Phe Leu Lys Met Arg Val Leu Ala Glu Ile
          35                  40                  45

 gct gaa gaa aca caa gga aga agt caa gtt att tct ctc tgt ccc aac      192
 Ala Glu Glu Thr Gln Gly Arg Ser Gln Val Ile Ser Leu Cys Pro Asn
      50                  55                  60

 ccc cag gac acc cag gct tct gct gct gtt aag agc aag gcc cag ggg      240
 Pro Gln Asp Thr Gln Ala Ser Ala Ala Val Lys Ser Lys Ala Gln Gly
  65                  70                  75                  80

 atg ctg gag gga gag ggt gca gca gga ggc aag ggc ttg cgg agg gcc      288
 Met Leu Glu Gly Glu Gly Ala Ala Gly Gly Lys Gly Leu Arg Arg Ala
                  85                  90                  95

 agg gag aag cag ctg ggg tgg cca tcg ccc tgt gag gtg gtc acc aca      336
 Arg Glu Lys Gln Leu Gly Trp Pro Ser Pro Cys Glu Val Val Thr Thr
             100                 105                 110

 ggc atg aat gcg gag cct gga gcc cca gtg ctt gtg ctg gca gcc agc      384
 Gly Met Asn Ala Glu Pro Gly Ala Pro Val Leu Val Leu Ala Ala Ser
         115                 120                 125

 cct ggc cag ctg gca tcc aga gcc cac tgg ggc tgc aca gcc gta tgc      432
 Pro Gly Gln Leu Ala Ser Arg Ala His Trp Gly Cys Thr Ala Val Cys
     130                 135                 140

 ata aag gcc cca gtc ggg gaa cag cct cct atg gca cag agt gat gga      480
 Ile Lys Ala Pro Val Gly Glu Gln Pro Pro Met Ala Gln Ser Asp Gly
 145                 150                 155                 160

 aaa tca cct ggc gcc gaa gaa cca tca ttg gac agg aat ata gaa ggc      528
 Lys Ser Pro Gly Ala Glu Glu Pro Ser Leu Asp Arg Asn Ile Glu Gly
                 165                 170                 175

 aag cta cat ggc aga cag gcc caa tcg gcc aca tcg cta atc aca gcc      576
 Lys Leu His Gly Arg Gln Ala Gln Ser Ala Thr Ser Leu Ile Thr Ala
             180                 185                 190

 gtc ctt tct gct gag cta gga ctt ggc ctc aac atc att ctg aag cca      624
 Val Leu Ser Ala Glu Leu Gly Leu Gly Leu Asn Ile Ile Leu Lys Pro
         195                 200                 205

 gtg ctc cag gaa tcc agt gct cat cag tca gca tca gga ccc gag agc      672
 Val Leu Gln Glu Ser Ser Ala His Gln Ser Ala Ser Gly Pro Glu Ser
     210                 215                 220

 aaa cct gtt ttc cgt tgc tga                                          693
 Lys Pro Val Phe Arg Cys 
 225                 230





      <210> 736
      <211> 303
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(303)

      <400> 736
  atg ctg gga tcc cgc tgg gcc cca ccc ctg cca ctg ctg ctt act gct      48
  Met Leu Gly Ser Arg Trp Ala Pro Pro Leu Pro Leu Leu Leu Thr Ala
    1               5                  10                  15

 ctt gag ccc gcc ttg ctg ggc cca gca ctc ggg ggc cat gac aga ggc       96
 Leu Glu Pro Ala Leu Leu Gly Pro Ala Leu Gly Gly His Asp Arg Gly
              20                  25                  30

 tgg ctg gtg gac tca gca ccc ttg cag agc ccc cag gaa gca gtg ccc      144
 Trp Leu Val Asp Ser Ala Pro Leu Gln Ser Pro Gln Glu Ala Val Pro
          35                  40                  45

 gta ggc tgc cag ctc ggt cgg ctc tct gaa act tcc cag gaa gcc atg      192
 Val Gly Cys Gln Leu Gly Arg Leu Ser Glu Thr Ser Gln Glu Ala Met
      50                  55                  60

 gcc cac aag gaa gag aat agc aac cta ggg gca acc gtg gca gct ctg      240
 Ala His Lys Glu Glu Asn Ser Asn Leu Gly Ala Thr Val Ala Ala Leu
  65                  70                  75                  80

 caa gaa gcg aac gaa cgc cca gag aag cgg gtg tgg gag agt gga aat      288
 Gln Glu Ala Asn Glu Arg Pro Glu Lys Arg Val Trp Glu Ser Gly Asn
                  85                  90                  95

 gca gct gac ccc tga                                                  303
 Ala Ala Asp Pro 
             100





      <210> 737
      <211> 831
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(831)

      <400> 737
  atg cga aga aag aac ctc aca gag gta aca gag ttt gtt ttc ctg gga      48
  Met Arg Arg Lys Asn Leu Thr Glu Val Thr Glu Phe Val Phe Leu Gly
    1               5                  10                  15

 ttc tcc aga ttc cac aaa cat cac atc act ctc ttt gtg gtt ttt ctc       96
 Phe Ser Arg Phe His Lys His His Ile Thr Leu Phe Val Val Phe Leu
              20                  25                  30

 atc ctg tac aca tta act gtg gct ggc aat gcc atc atc atg acc atc      144
 Ile Leu Tyr Thr Leu Thr Val Ala Gly Asn Ala Ile Ile Met Thr Ile
          35                  40                  45

 atc tgc att gac cgt cac ctc cac act ccc atg tac ttc ttc ctg agc      192
 Ile Cys Ile Asp Arg His Leu His Thr Pro Met Tyr Phe Phe Leu Ser
      50                  55                  60

 atg ctg gct agc tca aag aca gtg tac aca ctg ttc atc att cca cag      240
 Met Leu Ala Ser Ser Lys Thr Val Tyr Thr Leu Phe Ile Ile Pro Gln
  65                  70                  75                  80

 atg ctc tcc agc ttc gta acc cag acc cag cca atc tcc cta gca ggt      288
 Met Leu Ser Ser Phe Val Thr Gln Thr Gln Pro Ile Ser Leu Ala Gly
                  85                  90                  95

 tgt acc acc caa acg ttc ttc ttt gtt acc ttg gcc atc aac aat tgc      336
 Cys Thr Thr Gln Thr Phe Phe Phe Val Thr Leu Ala Ile Asn Asn Cys
             100                 105                 110

 ttc ttg ctc aca gtg atg ggc tat gac cac tat atg gcc atc tgc aat      384
 Phe Leu Leu Thr Val Met Gly Tyr Asp His Tyr Met Ala Ile Cys Asn
         115                 120                 125

 ccc ttg aga tac agg gtc att acg agc aag aag gtg tgt gtc cag ctg      432
 Pro Leu Arg Tyr Arg Val Ile Thr Ser Lys Lys Val Cys Val Gln Leu
     130                 135                 140

 gtg tgt gga gcc ttt agc att ggc ctg gcc atg gca gct gtc cag gta      480
 Val Cys Gly Ala Phe Ser Ile Gly Leu Ala Met Ala Ala Val Gln Val
 145                 150                 155                 160

 aca tcc ata ttt acc tta cct ttt tgt cac acg gtg gtt ggt cat ttc      528
 Thr Ser Ile Phe Thr Leu Pro Phe Cys His Thr Val Val Gly His Phe
                 165                 170                 175

 ttc tgt gac atc ctc cct gtc atg aaa ctc tcc tgt att aat acc act      576
 Phe Cys Asp Ile Leu Pro Val Met Lys Leu Ser Cys Ile Asn Thr Thr
             180                 185                 190

 atc aat gag ata atc aat ttt gtt gtc agg tta ttt gtc atc ctg gtc      624
 Ile Asn Glu Ile Ile Asn Phe Val Val Arg Leu Phe Val Ile Leu Val
         195                 200                 205

 ccc atg ggt ctg gtc ttc atc tcc tat gtc ctc atc atc tcc act gtc      672
 Pro Met Gly Leu Val Phe Ile Ser Tyr Val Leu Ile Ile Ser Thr Val
     210                 215                 220

 ctc aag att gcc tca gct gag ggt tgg aag aag acc ttt gcc acc tgt      720
 Leu Lys Ile Ala Ser Ala Glu Gly Trp Lys Lys Thr Phe Ala Thr Cys
 225                 230                 235                 240

 gcc ttc cac ctc act gtg gtc att gtc cat tat ggc tgt gct tcc att      768
 Ala Phe His Leu Thr Val Val Ile Val His Tyr Gly Cys Ala Ser Ile
                 245                 250                 255

 gcc tac ctc atg ccc aag tca gaa aac tct ata gaa caa gac ctc ctt      816
 Ala Tyr Leu Met Pro Lys Ser Glu Asn Ser Ile Glu Gln Asp Leu Leu
             260                 265                 270

 ctc tca gtg acc taa                                                  831
 Leu Ser Val Thr 
         275





      <210> 738
      <211> 843
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(843)

      <400> 738
  atg gcc ctg ggc tgg gct gct tgc cta gga aca act ttc tcc cgt ctt      48
  Met Ala Leu Gly Trp Ala Ala Cys Leu Gly Thr Thr Phe Ser Arg Leu
    1               5                  10                  15

 tgt ctc tac ggc agt acc ggc caa aag gga aga gac tcg aag act gcc       96
 Cys Leu Tyr Gly Ser Thr Gly Gln Lys Gly Arg Asp Ser Lys Thr Ala
              20                  25                  30

 aaa aga cga agg ctt cct ggt tct gaa tct gca ttc ata gaa ata gtc      144
 Lys Arg Arg Arg Leu Pro Gly Ser Glu Ser Ala Phe Ile Glu Ile Val
          35                  40                  45

 ttt gga gta tgg gaa cag tgc ttt cat atg att ttt gga ggg acg cat      192
 Phe Gly Val Trp Glu Gln Cys Phe His Met Ile Phe Gly Gly Thr His
      50                  55                  60

 ttt aag aaa gat gaa gat cct gtt atc cca atg gat att atc aag ccc      240
 Phe Lys Lys Asp Glu Asp Pro Val Ile Pro Met Asp Ile Ile Lys Pro
  65                  70                  75                  80

 agc cct gtg att gcc tct cct acc gtc agc cct tcc ctc cag agg aga      288
 Ser Pro Val Ile Ala Ser Pro Thr Val Ser Pro Ser Leu Gln Arg Arg
                  85                  90                  95

 gcc ttc tct gaa ctt ctt agt gat gct agt gcc cct cac gcc agt gca      336
 Ala Phe Ser Glu Leu Leu Ser Asp Ala Ser Ala Pro His Ala Ser Ala
             100                 105                 110

 ttc ccc atg gcc ata gaa tat gat gca tcc tct ggg cct ccc atg gaa      384
 Phe Pro Met Ala Ile Glu Tyr Asp Ala Ser Ser Gly Pro Pro Met Glu
         115                 120                 125

 cat tcc cct ctg tct gcc ttc ggg ctc tac aca caa aaa aaa ttc ttt      432
 His Ser Pro Leu Ser Ala Phe Gly Leu Tyr Thr Gln Lys Lys Phe Phe
     130                 135                 140

 cag gca aat cac ccc act tct agt cca cct gta tca aca ggc cct cta      480
 Gln Ala Asn His Pro Thr Ser Ser Pro Pro Val Ser Thr Gly Pro Leu
 145                 150                 155                 160

 aaa agc aga tgc cag ggt gga atc aga tgt gca aga cat att tac tgc      528
 Lys Ser Arg Cys Gln Gly Gly Ile Arg Cys Ala Arg His Ile Tyr Cys
                 165                 170                 175

 gtg gaa aat cct ggg aag gat aat gga gca gga gca gga ata gac agg      576
 Val Glu Asn Pro Gly Lys Asp Asn Gly Ala Gly Ala Gly Ile Asp Arg
             180                 185                 190

 aag ggc cct cag atc atg aca ctg gtt aaa gga gag agg gaa aga aga      624
 Lys Gly Pro Gln Ile Met Thr Leu Val Lys Gly Glu Arg Glu Arg Arg
         195                 200                 205

 aag act gga tta gaa gca cct cag aga tgg gca tcc act agt gtt cac      672
 Lys Thr Gly Leu Glu Ala Pro Gln Arg Trp Ala Ser Thr Ser Val His
     210                 215                 220

 acc atg cat gat cat tgg cta aga gca gtc tat ggg gag cat gcg ctt      720
 Thr Met His Asp His Trp Leu Arg Ala Val Tyr Gly Glu His Ala Leu
 225                 230                 235                 240

 gtt aca aat gga gtt ggg gag cca gaa ggt cag ggg cag ggc ctg gca      768
 Val Thr Asn Gly Val Gly Glu Pro Glu Gly Gln Gly Gln Gly Leu Ala
                 245                 250                 255

 gtc aac tat gct ccc cag agc aga tct gag cgg cac att ttc ccg gtc      816
 Val Asn Tyr Ala Pro Gln Ser Arg Ser Glu Arg His Ile Phe Pro Val
             260                 265                 270

 acg gct gct gga gga ttt aga gtt tga                                  843
 Thr Ala Ala Gly Gly Phe Arg Val 
         275                 280





      <210> 739
      <211> 480
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(480)

      <400> 739
  atg cac tgg ggt gct cct tct aaa cat ttg gcc ttg gcc att ctt ccc      48
  Met His Trp Gly Ala Pro Ser Lys His Leu Ala Leu Ala Ile Leu Pro
    1               5                  10                  15

 acc agc cct ctg agg aag ctt gcg ctc ctc tat tcc cac cca cac cta       96
 Thr Ser Pro Leu Arg Lys Leu Ala Leu Leu Tyr Ser His Pro His Leu
              20                  25                  30

 aag aac tgg gat cca cgg ctg ccc tcc acc tgg cgt agc ccc ggg aag      144
 Lys Asn Trp Asp Pro Arg Leu Pro Ser Thr Trp Arg Ser Pro Gly Lys
          35                  40                  45

 ggt gac agg aag ctt gtg tgg gct ggg gac gct ggg ggc cta gcg gag      192
 Gly Asp Arg Lys Leu Val Trp Ala Gly Asp Ala Gly Gly Leu Ala Glu
      50                  55                  60

 gtt cgc cac ctg cag ggg gtc ttc agg agt cgg act tca gac gcc aag      240
 Val Arg His Leu Gln Gly Val Phe Arg Ser Arg Thr Ser Asp Ala Lys
  65                  70                  75                  80

 agg gca gat gga gga cac cgt cgt cgc tct cca cgg tct ctc ttc gct      288
 Arg Ala Asp Gly Gly His Arg Arg Arg Ser Pro Arg Ser Leu Phe Ala
                  85                  90                  95

 agt gcc cag gag ggc gca cag cta gcg aag cga ctc gag ggt cag cga      336
 Ser Ala Gln Glu Gly Ala Gln Leu Ala Lys Arg Leu Glu Gly Gln Arg
             100                 105                 110

 ata agc gct gga ttc ccg cag gct ccg gcg acc cca gac ccg gcc ctc      384
 Ile Ser Ala Gly Phe Pro Gln Ala Pro Ala Thr Pro Asp Pro Ala Leu
         115                 120                 125

 cgg cga aga cag gaa aac gtg tgt cga gag tcg ctg gag gga acc gtc      432
 Arg Arg Arg Gln Glu Asn Val Cys Arg Glu Ser Leu Glu Gly Thr Val
     130                 135                 140

 cgc aaa tcg aag aag aaa cca aat cag cag cga aca cct gca aat tag      480
 Arg Lys Ser Lys Lys Lys Pro Asn Gln Gln Arg Thr Pro Ala Asn 
 145                 150                 155





      <210> 740
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 740
  atg aag caa aat gct atg ctg aaa aga tca aga ttc ctg ctc ctc ctc      48
  Met Lys Gln Asn Ala Met Leu Lys Arg Ser Arg Phe Leu Leu Leu Leu
    1               5                  10                  15

 cca tcc cct gct cct cct gcc cag cag cga agg gca gaa ccc tcg gct       96
 Pro Ser Pro Ala Pro Pro Ala Gln Gln Arg Arg Ala Glu Pro Ser Ala
              20                  25                  30

 gcc gcc ctc ctt cgc tct gac caa gaa gag gct gga aca gat gga gaa      144
 Ala Ala Leu Leu Arg Ser Asp Gln Glu Glu Ala Gly Thr Asp Gly Glu
          35                  40                  45

 cac atc tgg aaa gga gaa atg ctc caa gag ttg gac act gct gga aaa      192
 His Ile Trp Lys Gly Glu Met Leu Gln Glu Leu Asp Thr Ala Gly Lys
      50                  55                  60

 gga tcc tgg cat acc tcc taa                                          213
 Gly Ser Trp His Thr Ser 
  65                  70





      <210> 741
      <211> 681
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(681)

      <400> 741
  atg gcc cac tgg gct gtg agc ctc ttg gtc cgc ttc ttc atg aag atc      48
  Met Ala His Trp Ala Val Ser Leu Leu Val Arg Phe Phe Met Lys Ile
    1               5                  10                  15

 agg gac tcc ttc ccg ctg ccc atc agg tcc aga agg ggt aga ggg tac       96
 Arg Asp Ser Phe Pro Leu Pro Ile Arg Ser Arg Arg Gly Arg Gly Tyr
              20                  25                  30

 ccc cgc ccc ctg gca ccc acc ctt gct gtg cag gag cag act gtg gcg      144
 Pro Arg Pro Leu Ala Pro Thr Leu Ala Val Gln Glu Gln Thr Val Ala
          35                  40                  45

 cag gat ctg gtc cac ctt cac agc gat gtc gga gac gtt ctg ggc aat      192
 Gln Asp Leu Val His Leu His Ser Asp Val Gly Asp Val Leu Gly Asn
      50                  55                  60

 agc ctg gat ccg ctc cat gag gcc ggc ccc agg ggg cat cct aag tgg      240
 Ser Leu Asp Pro Leu His Glu Ala Gly Pro Arg Gly His Pro Lys Trp
  65                  70                  75                  80

 gaa aag cca gag gcc cag ttt aag ctc cgt tta tcc cta tac aag gta      288
 Glu Lys Pro Glu Ala Gln Phe Lys Leu Arg Leu Ser Leu Tyr Lys Val
                  85                  90                  95

 ctg gtc ttt atg gct gca cat aat ggg aat tcg atg aag gat ttt tcc      336
 Leu Val Phe Met Ala Ala His Asn Gly Asn Ser Met Lys Asp Phe Ser
             100                 105                 110

 aac ctg ggc tcc gtt cgg gtc tgc aaa ccc cac ctc tcc tcc tct tct      384
 Asn Leu Gly Ser Val Arg Val Cys Lys Pro His Leu Ser Ser Ser Ser
         115                 120                 125

 gag cct agc tgc cag tcc agg ggc cca atg gag gat gcc gtg ggt tgg      432
 Glu Pro Ser Cys Gln Ser Arg Gly Pro Met Glu Asp Ala Val Gly Trp
     130                 135                 140

 gct ccc cag aag cag agc ctg gga caa ggg ttt gag ggt acc ttc tgt      480
 Ala Pro Gln Lys Gln Ser Leu Gly Gln Gly Phe Glu Gly Thr Phe Cys
 145                 150                 155                 160

 gcg gat ggt gaa tgg cga gtc ccc cag gcg ccg ggc cga gaa ctg gcc      528
 Ala Asp Gly Glu Trp Arg Val Pro Gln Ala Pro Gly Arg Glu Leu Ala
                 165                 170                 175

 tcc cag aga cgt cat cag gaa gca gag agt gaa gaa gcc gat gcc cag      576
 Ser Gln Arg Arg His Gln Glu Ala Glu Ser Glu Glu Ala Asp Ala Gln
             180                 185                 190

 gac aaa aag cct gcg gag agg aag gag gcg ggt cag gag ggc agg aag      624
 Asp Lys Lys Pro Ala Glu Arg Lys Glu Ala Gly Gln Glu Gly Arg Lys
         195                 200                 205

 ggc cat cgt gcc ctg acg ctc cac cac gta ccg gct gca caa atg ttt      672
 Gly His Arg Ala Leu Thr Leu His His Val Pro Ala Ala Gln Met Phe
     210                 215                 220

 tac gaa tga                                                          681
 Tyr Glu 
 225





      <210> 742
      <211> 1062
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1062)

      <400> 742
  atg aat cgc acc acc ttt ttt ctg gaa gga ctg tct gtg ctc att tca      48
  Met Asn Arg Thr Thr Phe Phe Leu Glu Gly Leu Ser Val Leu Ile Ser
    1               5                  10                  15

 agc tgg ttc cgc ctt ctc cgc cag aaa cac aaa tcc cat gac cca tcc       96
 Ser Trp Phe Arg Leu Leu Arg Gln Lys His Lys Ser His Asp Pro Ser
              20                  25                  30

 ggc agg gag cga gct gca tcg gag ccc gcg tcg cag tct tca gag cgg      144
 Gly Arg Glu Arg Ala Ala Ser Glu Pro Ala Ser Gln Ser Ser Glu Arg
          35                  40                  45

 aaa cac cga acc cga cag gag ccc gca aga caa aag caa ccc ggc gaa      192
 Lys His Arg Thr Arg Gln Glu Pro Ala Arg Gln Lys Gln Pro Gly Glu
      50                  55                  60

 atc tac ggg cag caa aga gca ccc tat gaa aag tcg gtc gca ggg aag      240
 Ile Tyr Gly Gln Gln Arg Ala Pro Tyr Glu Lys Ser Val Ala Gly Lys
  65                  70                  75                  80

 cga gga ccg cct ggc tct tat ttc aaa tca gtt ctc aga gac gtt gta      288
 Arg Gly Pro Pro Gly Ser Tyr Phe Lys Ser Val Leu Arg Asp Val Val
                  85                  90                  95

 ggt ggc tgg ctt ggg ccg cgg agg agc ttc gcc aat cag aag caa ggg      336
 Gly Gly Trp Leu Gly Pro Arg Arg Ser Phe Ala Asn Gln Lys Gln Gly
             100                 105                 110

 gga tat aaa aac gat aga caa gaa aca caa cga aca agg aaa tta cat      384
 Gly Tyr Lys Asn Asp Arg Gln Glu Thr Gln Arg Thr Arg Lys Leu His
         115                 120                 125

 aat atc tta gag gat aag ccc tat ggg gaa ata aat caa att ttc ctt      432
 Asn Ile Leu Glu Asp Lys Pro Tyr Gly Glu Ile Asn Gln Ile Phe Leu
     130                 135                 140

 caa gtt gga cag cgg aag aat gga tat gca aga cct caa aaa agt tgc      480
 Gln Val Gly Gln Arg Lys Asn Gly Tyr Ala Arg Pro Gln Lys Ser Cys
 145                 150                 155                 160

 ctt cca tgt aac att ttc cag tat gtg ttc cag aaa aaa atg aaa gag      528
 Leu Pro Cys Asn Ile Phe Gln Tyr Val Phe Gln Lys Lys Met Lys Glu
                 165                 170                 175

 aaa acc aag aaa gag aaa aaa tgg aat tta gga aac aca aga att aag      576
 Lys Thr Lys Lys Glu Lys Lys Trp Asn Leu Gly Asn Thr Arg Ile Lys
             180                 185                 190

 cca gag aaa ggc aaa gaa aac atg gga aag gtg gtg cga ttc att gtt      624
 Pro Glu Lys Gly Lys Glu Asn Met Gly Lys Val Val Arg Phe Ile Val
         195                 200                 205

 cga gcg aaa ctt aca tgt gtt ggc tct ctg atc ata aag gaa gat agg      672
 Arg Ala Lys Leu Thr Cys Val Gly Ser Leu Ile Ile Lys Glu Asp Arg
     210                 215                 220

 gaa cag gca gaa gct gtc aag gga gat tct ctg gaa gca tta aga cag      720
 Glu Gln Ala Glu Ala Val Lys Gly Asp Ser Leu Glu Ala Leu Arg Gln
 225                 230                 235                 240

 gtt gct aat gca tcc cgc gaa gct gac cta atg cta ctt cag tgg gtc      768
 Val Ala Asn Ala Ser Arg Glu Ala Asp Leu Met Leu Leu Gln Trp Val
                 245                 250                 255

 tat ttt tct tct gtg gct cag ctc gaa tgt gat att cag gaa gtc gac      816
 Tyr Phe Ser Ser Val Ala Gln Leu Glu Cys Asp Ile Gln Glu Val Asp
             260                 265                 270

 tgt cag gca tgc aaa ttg aga gaa aaa tat gcc aca tta aat cat gat      864
 Cys Gln Ala Cys Lys Leu Arg Glu Lys Tyr Ala Thr Leu Asn His Asp
         275                 280                 285

 ggt tta ata agc aga cct cca ggg aac tgc att gag gaa gga aaa ttc      912
 Gly Leu Ile Ser Arg Pro Pro Gly Asn Cys Ile Glu Glu Gly Lys Phe
     290                 295                 300

 aaa gca atg gaa aca aaa tca gtc ctt aca ggt ttc acc gtt ggg att      960
 Lys Ala Met Glu Thr Lys Ser Val Leu Thr Gly Phe Thr Val Gly Ile
 305                 310                 315                 320

 tgg acc cgg agt gaa aag agg ata atg gtc tca gag cag cct ctg gtg     1008
 Trp Thr Arg Ser Glu Lys Arg Ile Met Val Ser Glu Gln Pro Leu Val
                 325                 330                 335

 gct gaa tgt caa aag ctc aag aag tca gag gcc acc tta cta gtg ttc     1056
 Ala Glu Cys Gln Lys Leu Lys Lys Ser Glu Ala Thr Leu Leu Val Phe
             340                 345                 350

 tct tga                                                             1062
 Ser 






      <210> 743
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 743
  atg agt cct agg agg cgc tgg ctc ttt ggc ggc tcg gag gag cgg ctg      48
  Met Ser Pro Arg Arg Arg Trp Leu Phe Gly Gly Ser Glu Glu Arg Leu
    1               5                  10                  15

 ctg ctg ctg ctg ctg ctg ctg gtg gcc cct ttg cag aat gag cct cgc       96
 Leu Leu Leu Leu Leu Leu Leu Val Ala Pro Leu Gln Asn Glu Pro Arg
              20                  25                  30

 agg cag tca ccg ttc tgt caa ctg aga gga gga gcc cgc ttt ggt agt      144
 Arg Gln Ser Pro Phe Cys Gln Leu Arg Gly Gly Ala Arg Phe Gly Ser
          35                  40                  45

 gct gtc ctt atg gca aga ata tat aga agt tgg agg gaa gat aaa ctc      192
 Ala Val Leu Met Ala Arg Ile Tyr Arg Ser Trp Arg Glu Asp Lys Leu
      50                  55                  60

 tct tct gga tgt ctg agg tac tgt gta gca gag ccc ttc caa tag          237
 Ser Ser Gly Cys Leu Arg Tyr Cys Val Ala Glu Pro Phe Gln 
  65                  70                  75





      <210> 744
      <211> 195
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(195)

      <400> 744
  atg tcc tgt cca gtg cca aat ttc tca aat gga aga ttc acc act ttc      48
  Met Ser Cys Pro Val Pro Asn Phe Ser Asn Gly Arg Phe Thr Thr Phe
    1               5                  10                  15

 atg gtc tcc tgc ttt ttc aag acc gca agg gtc agc acc acc ttc ttc       96
 Met Val Ser Cys Phe Phe Lys Thr Ala Arg Val Ser Thr Thr Phe Phe
              20                  25                  30

 cct ttg gcc ttc ttt ctt ttt cgc acc ttg gaa tca att acc tat ccc      144
 Pro Leu Ala Phe Phe Leu Phe Arg Thr Leu Glu Ser Ile Thr Tyr Pro
          35                  40                  45

 tta tct cac aac ttg ata gtg ata gat att gaa tgc tta tgt tct gat      192
 Leu Ser His Asn Leu Ile Val Ile Asp Ile Glu Cys Leu Cys Ser Asp
      50                  55                  60

 tag                                                                  195
 






      <210> 745
      <211> 516
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(516)

      <400> 745
  atg tct ccg ctg cgc tcg atg ctc cct cgc gcg ctc ctg ctc tcg cct      48
  Met Ser Pro Leu Arg Ser Met Leu Pro Arg Ala Leu Leu Leu Ser Pro
    1               5                  10                  15

 ctt ccg ctc gcg ctc tct cta gta aaa cgc gcc gct cct ttc cct cgg       96
 Leu Pro Leu Ala Leu Ser Leu Val Lys Arg Ala Ala Pro Phe Pro Arg
              20                  25                  30

 ttt ccc tct ggg ttc tcc tgg ttc cgg caa ccc gga cag aca agc ctc      144
 Phe Pro Ser Gly Phe Ser Trp Phe Arg Gln Pro Gly Gln Thr Ser Leu
          35                  40                  45

 ttg ccg cac gac ggc cgg atc cca gaa cag cct tgc tct cct ctt cgg      192
 Leu Pro His Asp Gly Arg Ile Pro Glu Gln Pro Cys Ser Pro Leu Arg
      50                  55                  60

 gag cgc aag cca ggg gcc ggg atg gac gct cct tca act aaa tgc gat      240
 Glu Arg Lys Pro Gly Ala Gly Met Asp Ala Pro Ser Thr Lys Cys Asp
  65                  70                  75                  80

 gta ctt aaa caa gca gcg cct tat agg acc gcg aac cga gcc gaa agg      288
 Val Leu Lys Gln Ala Ala Pro Tyr Arg Thr Ala Asn Arg Ala Glu Arg
                  85                  90                  95

 gcc ccg cta ctg cca tct agt gct cac aga acg gca tcg ccg cgg ctc      336
 Ala Pro Leu Leu Pro Ser Ser Ala His Arg Thr Ala Ser Pro Arg Leu
             100                 105                 110

 ttc ttc gct gtg tgt ctg tgc caa gtc tat cca acg ccg cca aag tcc      384
 Phe Phe Ala Val Cys Leu Cys Gln Val Tyr Pro Thr Pro Pro Lys Ser
         115                 120                 125

 cct ctg ctc tca gca aac aca gca gta agt aga gta cta cag cag gac      432
 Pro Leu Leu Ser Ala Asn Thr Ala Val Ser Arg Val Leu Gln Gln Asp
     130                 135                 140

 ctg aca tcc tgc att gag caa tat gga ttg gaa gct cca ttt ctt ctc      480
 Leu Thr Ser Cys Ile Glu Gln Tyr Gly Leu Glu Ala Pro Phe Leu Leu
 145                 150                 155                 160

 cct cat cct gtg ttg att cca gcc caa gat gtt taa                      516
 Pro His Pro Val Leu Ile Pro Ala Gln Asp Val 
                 165                 170





      <210> 746
      <211> 882
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(882)

      <400> 746
  atg gtg ctg ctg ctg ctg gtg gcc atc ccg ctg ctg gtg cac agc tcc      48
  Met Val Leu Leu Leu Leu Val Ala Ile Pro Leu Leu Val His Ser Ser
    1               5                  10                  15

 cgc ggg cca gcg cac tac gag atg ctg ggt cgc tgc cgc atg gtg tgc       96
 Arg Gly Pro Ala His Tyr Glu Met Leu Gly Arg Cys Arg Met Val Cys
              20                  25                  30

 gac ccg cat ggg ccc cgt ggc cct ggt ccc gac ggc gcg cct gct tcc      144
 Asp Pro His Gly Pro Arg Gly Pro Gly Pro Asp Gly Ala Pro Ala Ser
          35                  40                  45

 gtg ccc ccc ttc ccg cca ggc gcc aag gga gag gtg ggc cgg cgc ggg      192
 Val Pro Pro Phe Pro Pro Gly Ala Lys Gly Glu Val Gly Arg Arg Gly
      50                  55                  60

 aaa gca ggc ctg cgg ggg ccc cct gga cca cca ggt cca aga ggg ccc      240
 Lys Ala Gly Leu Arg Gly Pro Pro Gly Pro Pro Gly Pro Arg Gly Pro
  65                  70                  75                  80

 cca gga gaa ccc ggc agg cca ggc ccc ccg ggc cct ccc ggt cca ggt      288
 Pro Gly Glu Pro Gly Arg Pro Gly Pro Pro Gly Pro Pro Gly Pro Gly
                  85                  90                  95

 ccg ggc ggg gtg gcg ccc gct gcc ggc tac gtg cct cgc att gct ttc      336
 Pro Gly Gly Val Ala Pro Ala Ala Gly Tyr Val Pro Arg Ile Ala Phe
             100                 105                 110

 tac gcg ggc ctg cgg cgg ccc cac gag ggt tac gag gtg ctg cgc ttc      384
 Tyr Ala Gly Leu Arg Arg Pro His Glu Gly Tyr Glu Val Leu Arg Phe
         115                 120                 125

 gac gac gtg gtg acc aac gtg ggc aac gcc tac gag gca gcc agc ggc      432
 Asp Asp Val Val Thr Asn Val Gly Asn Ala Tyr Glu Ala Ala Ser Gly
     130                 135                 140

 aag ttt act tgc ccc atg cca ggc gtc tac ttc ttc gct tac cac gtg      480
 Lys Phe Thr Cys Pro Met Pro Gly Val Tyr Phe Phe Ala Tyr His Val
 145                 150                 155                 160

 ctc atg cgc ggc ggc gac ggc acc agc atg tgg gcc gac ctc atg aag      528
 Leu Met Arg Gly Gly Asp Gly Thr Ser Met Trp Ala Asp Leu Met Lys
                 165                 170                 175

 aac gga cag ggc tgg ggg cct aga acg gcc ttg ccc tca gca gag tct      576
 Asn Gly Gln Gly Trp Gly Pro Arg Thr Ala Leu Pro Ser Ala Glu Ser
             180                 185                 190

 gtg gct tgg cag ctc aag ggc cag cca gga gcc tct gca atc atc tgc      624
 Val Ala Trp Gln Leu Lys Gly Gln Pro Gly Ala Ser Ala Ile Ile Cys
         195                 200                 205

 tta ttg cgc gtc acc gtc atc cag tgg gag agc ctt gtg gta cca cct      672
 Leu Leu Arg Val Thr Val Ile Gln Trp Glu Ser Leu Val Val Pro Pro
     210                 215                 220

 ttc tcc acc tat ggc tgc ggc ccg cag gaa gat gac ggg ttg cgc ttc      720
 Phe Ser Thr Tyr Gly Cys Gly Pro Gln Glu Asp Asp Gly Leu Arg Phe
 225                 230                 235                 240

 tgc tct gga gcc agc cct gtt gcc ggg aac tgc aac ccg caa gat gat      768
 Cys Ser Gly Ala Ser Pro Val Ala Gly Asn Cys Asn Pro Gln Asp Asp
                 245                 250                 255

 gcc aga gct cag ctt ccc tct ttt tat gtt gca gag ttt atg ctg ccc      816
 Ala Arg Ala Gln Leu Pro Ser Phe Tyr Val Ala Glu Phe Met Leu Pro
             260                 265                 270

 tgc act gag cag acg ctt tcg ctt acg cag ccc tgc cct tca cct tgc      864
 Cys Thr Glu Gln Thr Leu Ser Leu Thr Gln Pro Cys Pro Ser Pro Cys
         275                 280                 285

 cca gtg att ccg gaa taa                                              882
 Pro Val Ile Pro Glu 
     290





      <210> 747
      <211> 405
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(405)

      <400> 747
  atg gca atc caa aga gtg ttg caa ata cag gaa agg ctc atg tca tgg      48
  Met Ala Ile Gln Arg Val Leu Gln Ile Gln Glu Arg Leu Met Ser Trp
    1               5                  10                  15

 ctt ttt gtt gtt att gat aga gtt tgc agc tcc agc cag ggt gta ttt       96
 Leu Phe Val Val Ile Asp Arg Val Cys Ser Ser Ser Gln Gly Val Phe
              20                  25                  30

 atg aca ggg tgg aaa tgt gac ttg ggc aaa cag gaa gcc gta gcg gga      144
 Met Thr Gly Trp Lys Cys Asp Leu Gly Lys Gln Glu Ala Val Ala Gly
          35                  40                  45

 gaa aac aat ctg agc gag cat gag aaa aag gcc aca caa aca act cca      192
 Glu Asn Asn Leu Ser Glu His Glu Lys Lys Ala Thr Gln Thr Thr Pro
      50                  55                  60

 cag ccc tca gac agc cct gaa atc tgg tac aga tct gca agc aaa acg      240
 Gln Pro Ser Asp Ser Pro Glu Ile Trp Tyr Arg Ser Ala Ser Lys Thr
  65                  70                  75                  80

 ctg gga tgg atg gac cag tgt ttt cca gac ttg cca gac cca aag gag      288
 Leu Gly Trp Met Asp Gln Cys Phe Pro Asp Leu Pro Asp Pro Lys Glu
                  85                  90                  95

 cac ctc ggg cac tta tta gaa cac aga tgc cag gcc cct gcc ctc gag      336
 His Leu Gly His Leu Leu Glu His Arg Cys Gln Ala Pro Ala Leu Glu
             100                 105                 110

 ctg ctg ctt ccg cag atc tgc aca cac ctg gga aac acc aga tca gat      384
 Leu Leu Leu Pro Gln Ile Cys Thr His Leu Gly Asn Thr Arg Ser Asp
         115                 120                 125

 gaa ttt ggc cag gtg ctc taa                                          405
 Glu Phe Gly Gln Val Leu 
     130





      <210> 748
      <211> 930
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(930)

      <400> 748
  atg gct gcc ttc gcg gcg ggg ccc ctt tgc atg cct gtt tgc cat ctg      48
  Met Ala Ala Phe Ala Ala Gly Pro Leu Cys Met Pro Val Cys His Leu
    1               5                  10                  15

 tgt gtt tcc ttg gac gtg gcc cag tgg aac atc ggg agc ctc cgg acc       96
 Cys Val Ser Leu Asp Val Ala Gln Trp Asn Ile Gly Ser Leu Arg Thr
              20                  25                  30

 atc ctg gac atg gtg gag cgc gag tgc ggc acc atc atc gag ggc gtg      144
 Ile Leu Asp Met Val Glu Arg Glu Cys Gly Thr Ile Ile Glu Gly Val
          35                  40                  45

 aac acg ccc tac ctg tac ttc ggc atg tgg aag acc acc ttc gcc tgg      192
 Asn Thr Pro Tyr Leu Tyr Phe Gly Met Trp Lys Thr Thr Phe Ala Trp
      50                  55                  60

 cac acc gag gac atg gac ctg tac agc atc aac tac ctg cac ttt ggg      240
 His Thr Glu Asp Met Asp Leu Tyr Ser Ile Asn Tyr Leu His Phe Gly
  65                  70                  75                  80

 gag cct aag tcc tgg gac cgt ctg ccc tgt gca gag agc ccc tgt ggg      288
 Glu Pro Lys Ser Trp Asp Arg Leu Pro Cys Ala Glu Ser Pro Cys Gly
                  85                  90                  95

 gcg gga agt ggc gag cag ccg gca agg agg ccc agc cag aca gaa gca      336
 Ala Gly Ser Gly Glu Gln Pro Ala Arg Arg Pro Ser Gln Thr Glu Ala
             100                 105                 110

 ggg ggg tca ggg aca tgg gag gtg ggg gac cag cca gca gcg ggg cta      384
 Gly Gly Ser Gly Thr Trp Glu Val Gly Asp Gln Pro Ala Ala Gly Leu
         115                 120                 125

 aga ata tct gaa gag act gag cgc ctc aaa atc tct ttg gca atg cgg      432
 Arg Ile Ser Glu Glu Thr Glu Arg Leu Lys Ile Ser Leu Ala Met Arg
     130                 135                 140

 att gaa acc aga gcc agc acc tgc aac ttc ccc ccg cca act tcc cgc      480
 Ile Glu Thr Arg Ala Ser Thr Cys Asn Phe Pro Pro Pro Thr Ser Arg
 145                 150                 155                 160

 agc ccc ttc tgt cac cca ggc cgg ggg ggc cgg agt gca ggg gac tgt      528
 Ser Pro Phe Cys His Pro Gly Arg Gly Gly Arg Ser Ala Gly Asp Cys
                 165                 170                 175

 ggg cca ccg cca aga gca gaa gct ttg gct ctc act gca gca ggg aag      576
 Gly Pro Pro Pro Arg Ala Glu Ala Leu Ala Leu Thr Ala Ala Gly Lys
             180                 185                 190

 cca gat ggg gga tca gca tgt tcc tgg ggc tgc agg gac tcc cga gga      624
 Pro Asp Gly Gly Ser Ala Cys Ser Trp Gly Cys Arg Asp Ser Arg Gly
         195                 200                 205

 cgt cgt gag ctg atg gga cat ggt cag ctg ctt gca ctg gct cca agg      672
 Arg Arg Glu Leu Met Gly His Gly Gln Leu Leu Ala Leu Ala Pro Arg
     210                 215                 220

 cgg cga gag gaa ggc cct cct gag gag tgc cgc ggg gcc agc gca gtc      720
 Arg Arg Glu Glu Gly Pro Pro Glu Glu Cys Arg Gly Ala Ser Ala Val
 225                 230                 235                 240

 tgg ctg cag gtg gca ctg tcg ggc ccc aca atg gcc tct gcc ctg tcc      768
 Trp Leu Gln Val Ala Leu Ser Gly Pro Thr Met Ala Ser Ala Leu Ser
                 245                 250                 255

 ctt gga gtg gga ccc agg agt ctg gtg ggt gat gga gct ggc gag ccc      816
 Leu Gly Val Gly Pro Arg Ser Leu Val Gly Asp Gly Ala Gly Glu Pro
             260                 265                 270

 gtc cca ggc agc agc ctg aag gcc cat ggg gta gcg cgc tgg cgc ccg      864
 Val Pro Gly Ser Ser Leu Lys Ala His Gly Val Ala Arg Trp Arg Pro
         275                 280                 285

 ggg acc ctg gtg tgg gtt tgt act gct gct gct ggc gag cca acc act      912
 Gly Thr Leu Val Trp Val Cys Thr Ala Ala Ala Gly Glu Pro Thr Thr
     290                 295                 300

 ggg act tcc agc ttc tga                                              930
 Gly Thr Ser Ser Phe 
 305





      <210> 749
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 749
  atg ctg cct gtg ttt atg ttg ctt ctc cct atg gca tgt gct ctg agc      48
  Met Leu Pro Val Phe Met Leu Leu Leu Pro Met Ala Cys Ala Leu Ser
    1               5                  10                  15

 aga caa ggg tat aat tat aaa tct cca tcc act aac aag aac aat ggt       96
 Arg Gln Gly Tyr Asn Tyr Lys Ser Pro Ser Thr Asn Lys Asn Asn Gly
              20                  25                  30

 tgc atc cag caa cta gac tct ccc ttt gtg aag ctc tac acg gat acc      144
 Cys Ile Gln Gln Leu Asp Ser Pro Phe Val Lys Leu Tyr Thr Asp Thr
          35                  40                  45

 gtc ttg aat gca gaa gca aac caa aat cca gag att tta aaa tat ggt      192
 Val Leu Asn Ala Glu Ala Asn Gln Asn Pro Glu Ile Leu Lys Tyr Gly
      50                  55                  60

 atc tat aat tac aag aaa caa caa gaa acc aaa gag gaa tac aaa tac      240
 Ile Tyr Asn Tyr Lys Lys Gln Gln Glu Thr Lys Glu Glu Tyr Lys Tyr
  65                  70                  75                  80

 aac cat gcc ttg tgt ttc aag act ttc tag                              270
 Asn His Ala Leu Cys Phe Lys Thr Phe 
                  85





      <210> 750
      <211> 342
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(342)

      <400> 750
  atg aac tct ctg agt tgg ggg gct gcg aat gcc gtg ctg ctg ctg ctc      48
  Met Asn Ser Leu Ser Trp Gly Ala Ala Asn Ala Val Leu Leu Leu Leu
    1               5                  10                  15

 ctc ctg gcc tgg gcc agc ccc acc ttc atc agc atc aac cgc ggg gtg       96
 Leu Leu Ala Trp Ala Ser Pro Thr Phe Ile Ser Ile Asn Arg Gly Val
              20                  25                  30

 agg gtg atg aag ggc cac tct gcc ttc ctg tca gga gat gac ctg aag      144
 Arg Val Met Lys Gly His Ser Ala Phe Leu Ser Gly Asp Asp Leu Lys
          35                  40                  45

 ttt gcc atc cct aaa gag aaa gat gcc tgc aaa gtg gaa gtt gtg atg      192
 Phe Ala Ile Pro Lys Glu Lys Asp Ala Cys Lys Val Glu Val Val Met
      50                  55                  60

 aat gag cca ata acc cag agg gtt ggg aaa ctc act cca cag gtc ttt      240
 Asn Glu Pro Ile Thr Gln Arg Val Gly Lys Leu Thr Pro Gln Val Phe
  65                  70                  75                  80

 gac tgc cat ttc ctt ccc aac gaa gtc aag tat gtt cac aat ggt tgt      288
 Asp Cys His Phe Leu Pro Asn Glu Val Lys Tyr Val His Asn Gly Cys
                  85                  90                  95

 cca att ctt gat gaa gac aca gtg aag ctc aga ctt tac agt gtc ctt      336
 Pro Ile Leu Asp Glu Asp Thr Val Lys Leu Arg Leu Tyr Ser Val Leu
             100                 105                 110

 ata tag                                                              342
 Ile 






      <210> 751
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 751
  atg cta gtt gtg tac tcg agc gcg acg gtt gtt cgc ttg ctt cca tgt      48
  Met Leu Val Val Tyr Ser Ser Ala Thr Val Val Arg Leu Leu Pro Cys
    1               5                  10                  15

 gca tgt ttt cac cta gag ctg tcc ctg ctg cag ttc tgc gag gac gcg       96
 Ala Cys Phe His Leu Glu Leu Ser Leu Leu Gln Phe Cys Glu Asp Ala
              20                  25                  30

 gcg tat gac tgg gta aca gat aca cct gag ata aga att aag agt aaa      144
 Ala Tyr Asp Trp Val Thr Asp Thr Pro Glu Ile Arg Ile Lys Ser Lys
          35                  40                  45

 tta aat aaa act cat aga gtg caa aga gac ttc gac aaa gac aga aaa      192
 Leu Asn Lys Thr His Arg Val Gln Arg Asp Phe Asp Lys Asp Arg Lys
      50                  55                  60

 cta gct gtt ggc cag agt gaa agt cct ggt cat ccg act tcc gag aaa      240
 Leu Ala Val Gly Gln Ser Glu Ser Pro Gly His Pro Thr Ser Glu Lys
  65                  70                  75                  80

 cct cct tca acc tca tcg tct gct ggc tca cca gaa gct ttc aga aag      288
 Pro Pro Ser Thr Ser Ser Ser Ala Gly Ser Pro Glu Ala Phe Arg Lys
                  85                  90                  95

 cta atc cag tac ctg gct cct agg cgt ccc tgt cac tga                  327
 Leu Ile Gln Tyr Leu Ala Pro Arg Arg Pro Cys His 
             100                 105





      <210> 752
      <211> 1242
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1242)

      <400> 752
  atg gtc agt gtg gta gga gcc ggc cat cag cga gag ctg ctc cat gcc      48
  Met Val Ser Val Val Gly Ala Gly His Gln Arg Glu Leu Leu His Ala
    1               5                  10                  15

 tgg ctg ctg gga gct aga gcc tgc ggc cca ctg gct tgc ctc act gta       96
 Trp Leu Leu Gly Ala Arg Ala Cys Gly Pro Leu Ala Cys Leu Thr Val
              20                  25                  30

 gtt ggt ggt ggc agt gac aga gac tgc agc atg acc aga gtg gta gga      144
 Val Gly Gly Gly Ser Asp Arg Asp Cys Ser Met Thr Arg Val Val Gly
          35                  40                  45

 cag ggg cta tcc agg gct gca cct ttc gca gtg tgg ggc cct gcc cct      192
 Gln Gly Leu Ser Arg Ala Ala Pro Phe Ala Val Trp Gly Pro Ala Pro
      50                  55                  60

 gct gct gcc ctg gcc ctg gcc tgg aac ctg gtc ctg tca agg acc tgc      240
 Ala Ala Ala Leu Ala Leu Ala Trp Asn Leu Val Leu Ser Arg Thr Cys
  65                  70                  75                  80

 cct gac tct gcc atg gcc ctg gcc ctg ctc tgc ctt gtt cct ggc cct      288
 Pro Asp Ser Ala Met Ala Leu Ala Leu Leu Cys Leu Val Pro Gly Pro
                  85                  90                  95

 gac cca gac cca gac cct ttc ctg gct ctg cac tgg tct ttc cct ggc      336
 Asp Pro Asp Pro Asp Pro Phe Leu Ala Leu His Trp Ser Phe Pro Gly
             100                 105                 110

 cct gag ctg gca gtg gtc tgc ccc tgc ttt ggc cct gaa gtg gac ttg      384
 Pro Glu Leu Ala Val Val Cys Pro Cys Phe Gly Pro Glu Val Asp Leu
         115                 120                 125

 gag gtg tcc tgg ccc cgg tgt aac atg gct ctg cat tgg cct gtc tct      432
 Glu Val Ser Trp Pro Arg Cys Asn Met Ala Leu His Trp Pro Val Ser
     130                 135                 140

 gcc ctg ccc cta cca tcg cct tgc cct gct ctg ccc tgt ccc agt act      480
 Ala Leu Pro Leu Pro Ser Pro Cys Pro Ala Leu Pro Cys Pro Ser Thr
 145                 150                 155                 160

 gac ccg gcc acg cta ttt ccc cgc cct acc ctg cct tgg ctg tgc cct      528
 Asp Pro Ala Thr Leu Phe Pro Arg Pro Thr Leu Pro Trp Leu Cys Pro
                 165                 170                 175

 ggc tcg gtt ctg gcc ctg gcc ccg gcc ctg ccc tgg aca tgc tct gac      576
 Gly Ser Val Leu Ala Leu Ala Pro Ala Leu Pro Trp Thr Cys Ser Asp
             180                 185                 190

 act gcc tca gcc ttg gca cta gcc tgg ctc att ctt ggc atc agc cct      624
 Thr Ala Ser Ala Leu Ala Leu Ala Trp Leu Ile Leu Gly Ile Ser Pro
         195                 200                 205

 gct ctc tct gtg gac cgg ctc ttg tcc tgt cct gca ctg gcc ata cca      672
 Ala Leu Ser Val Asp Arg Leu Leu Ser Cys Pro Ala Leu Ala Ile Pro
     210                 215                 220

 tgc cct gcc ctg ccc tgc cct gac tca gcc ctg act cag cct tgg cct      720
 Cys Pro Ala Leu Pro Cys Pro Asp Ser Ala Leu Thr Gln Pro Trp Pro
 225                 230                 235                 240

 tgg cat tgc ccc tgg tcc tgc cat att tct tgc cct gtc cct acc cta      768
 Trp His Cys Pro Trp Ser Cys His Ile Ser Cys Pro Val Pro Thr Leu
                 245                 250                 255

 gcc ttg gcc ctg acc ctt acc ttg ctc tgg ccc tgc cct tgc cct aat      816
 Ala Leu Ala Leu Thr Leu Thr Leu Leu Trp Pro Cys Pro Cys Pro Asn
             260                 265                 270

 gca gcc cct ggc cct gtc atg acc ctg ccc tgg acc tgt cct ggc cct      864
 Ala Ala Pro Gly Pro Val Met Thr Leu Pro Trp Thr Cys Pro Gly Pro
         275                 280                 285

 ggc cct tcc ctg ctt gag acc ttg ccc tgg ttc tcc cat ggc cct gac      912
 Gly Pro Ser Leu Leu Glu Thr Leu Pro Trp Phe Ser His Gly Pro Asp
     290                 295                 300

 cct gaa atg cct ggc cct acc ctg gcc ttg ccc tgc tct ggc cct tgc      960
 Pro Glu Met Pro Gly Pro Thr Leu Ala Leu Pro Cys Ser Gly Pro Cys
 305                 310                 315                 320

 cct gac tct ggt cct gtc act gac cta gcc cca gcc ctg ttg ctg gtc     1008
 Pro Asp Ser Gly Pro Val Thr Asp Leu Ala Pro Ala Leu Leu Leu Val
                 325                 330                 335

 tta cca tgg ccc aga ccc tgc ctt ggc cct gcc ctg aca ctg tcc tgg     1056
 Leu Pro Trp Pro Arg Pro Cys Leu Gly Pro Ala Leu Thr Leu Ser Trp
             340                 345                 350

 acc ctg gct gtg cca aga acc tgc act gtc ctt gcc ctt gtt ttg ctc     1104
 Thr Leu Ala Val Pro Arg Thr Cys Thr Val Leu Ala Leu Val Leu Leu
         355                 360                 365

 ctg ccc caa acc tgg tcc tgc cca ggc cgt ttc tat ggc cct ggc cct     1152
 Leu Pro Gln Thr Trp Ser Cys Pro Gly Arg Phe Tyr Gly Pro Gly Pro
     370                 375                 380

 ggc cct gcc cag gtc ttg gca ctg gcc tgg ccc tgc cct ggc cct gcc     1200
 Gly Pro Ala Gln Val Leu Ala Leu Ala Trp Pro Cys Pro Gly Pro Ala
 385                 390                 395                 400

 ctg ccc tgg ccc tat gct ttc ctg gcc ctg cct tgg ccc tag             1242
 Leu Pro Trp Pro Tyr Ala Phe Leu Ala Leu Pro Trp Pro 
                 405                 410





      <210> 753
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 753
  atg gga ccc acc tca ggt ccc agc ctg ctg ctc ctg cta cta acc cac      48
  Met Gly Pro Thr Ser Gly Pro Ser Leu Leu Leu Leu Leu Leu Thr His
    1               5                  10                  15

 ctc ccc ctg gct ctg ggg agt ccc ata tgt gga aga ctg agg cct gtt       96
 Leu Pro Leu Ala Leu Gly Ser Pro Ile Cys Gly Arg Leu Arg Pro Val
              20                  25                  30

 gaa agt gca gag ctc agc cct ggc acc ctc tgt tcc caa gag ctc cat      144
 Glu Ser Ala Glu Leu Ser Pro Gly Thr Leu Cys Ser Gln Glu Leu His
          35                  40                  45

 gca ggg caa gga agt gga gca aca gtc agc ctg cag att tgg cac ata      192
 Ala Gly Gln Gly Ser Gly Ala Thr Val Ser Leu Gln Ile Trp His Ile
      50                  55                  60

 tgg ggc ggt caa gag aag acc ccg ctg gga tgg gcc ctg cac gga gtg      240
 Trp Gly Gly Gln Glu Lys Thr Pro Leu Gly Trp Ala Leu His Gly Val
  65                  70                  75                  80

 cta gga tac atc aac aaa cca gaa aga gac aaa gat ccc tgc ccg atg      288
 Leu Gly Tyr Ile Asn Lys Pro Glu Arg Asp Lys Asp Pro Cys Pro Met
                  85                  90                  95

 gga gcc aac agt cca cga gag gac aac aaa cca tga                      324
 Gly Ala Asn Ser Pro Arg Glu Asp Asn Lys Pro 
             100                 105





      <210> 754
      <211> 723
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(723)

      <400> 754
  atg tgg ctg ctc cca gct cta ctc ctt ctc tgc ctc tca gga aac acc      48
  Met Trp Leu Leu Pro Ala Leu Leu Leu Leu Cys Leu Ser Gly Asn Thr
    1               5                  10                  15

 cag gtc tcc ctg gca atc ttc ccc tta agc ttc aga cag acg gct gct       96
 Gln Val Ser Leu Ala Ile Phe Pro Leu Ser Phe Arg Gln Thr Ala Ala
              20                  25                  30

 gat ggg gcc atc tgg atg gag act tgg gac tcg ggc ttg tgt ttt cca      144
 Asp Gly Ala Ile Trp Met Glu Thr Trp Asp Ser Gly Leu Cys Phe Pro
          35                  40                  45

 ggc tgt ttg tct ctg aag ggc ccc ggc tct gtg act ggc act gcg ggg      192
 Gly Cys Leu Ser Leu Lys Gly Pro Gly Ser Val Thr Gly Thr Ala Gly
      50                  55                  60

 gac tct ctg aca gtg tgg tgt cag tat gag agc atg tac aag gga tat      240
 Asp Ser Leu Thr Val Trp Cys Gln Tyr Glu Ser Met Tyr Lys Gly Tyr
  65                  70                  75                  80

 aac aag tac tgg tgc cga gga cag tac gac acg tca tgt gag agc att      288
 Asn Lys Tyr Trp Cys Arg Gly Gln Tyr Asp Thr Ser Cys Glu Ser Ile
                  85                  90                  95

 gtg gag acc aag gga gaa gag aag gtg gag agg aat ggc cgc gtg tcc      336
 Val Glu Thr Lys Gly Glu Glu Lys Val Glu Arg Asn Gly Arg Val Ser
             100                 105                 110

 atc aga gac cac ccg gag gct ctc gcc ttc act gtg acc atg cag aac      384
 Ile Arg Asp His Pro Glu Ala Leu Ala Phe Thr Val Thr Met Gln Asn
         115                 120                 125

 ctc aat gaa gat gat gct gga tct tac tgg tgc aaa att cag aca gtg      432
 Leu Asn Glu Asp Asp Ala Gly Ser Tyr Trp Cys Lys Ile Gln Thr Val
     130                 135                 140

 tgg gtc ctg gat tca tgg tca cgc gat ccc tcg gac ctg gtt agg gtg      480
 Trp Val Leu Asp Ser Trp Ser Arg Asp Pro Ser Asp Leu Val Arg Val
 145                 150                 155                 160

 tat gtt tcc cca gca att aca acc cca agg agg acc aca cat cca gcc      528
 Tyr Val Ser Pro Ala Ile Thr Thr Pro Arg Arg Thr Thr His Pro Ala
                 165                 170                 175

 aca cct ccc atc ttc ctg gtg gtg aac cct ggg cga aac ctc agc acc      576
 Thr Pro Pro Ile Phe Leu Val Val Asn Pro Gly Arg Asn Leu Ser Thr
             180                 185                 190

 ggg gag gtg ttg acc caa aat tca ggg ttc cgg ctc agc agc cct cac      624
 Gly Glu Val Leu Thr Gln Asn Ser Gly Phe Arg Leu Ser Ser Pro His
         195                 200                 205

 ttc ctg ctc gtg gtc ctt ctg aag ctg ccc ctg ctc ctg agc atg ctg      672
 Phe Leu Leu Val Val Leu Leu Lys Leu Pro Leu Leu Leu Ser Met Leu
     210                 215                 220

 ggt gct gtc ttc tgg gtg aac agg cct cag tgg gct cct cct gga aga      720
 Gly Ala Val Phe Trp Val Asn Arg Pro Gln Trp Ala Pro Pro Gly Arg
 225                 230                 235                 240

 tag                                                                  723
 






      <210> 755
      <211> 798
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(798)

      <400> 755
  atg cca cca gcc ccc aaa gct ttc tca ggc ctc ctc ctt ttc cta tgc      48
  Met Pro Pro Ala Pro Lys Ala Phe Ser Gly Leu Leu Leu Phe Leu Cys
    1               5                  10                  15

 att cag gct tgt gga ttt act cca aca caa aat tgg caa att aac ttt       96
 Ile Gln Ala Cys Gly Phe Thr Pro Thr Gln Asn Trp Gln Ile Asn Phe
              20                  25                  30

 att cat atg ccc cat gtc tgt aaa ttt aaa tat ctc ctg gtt tgg atc      144
 Ile His Met Pro His Val Cys Lys Phe Lys Tyr Leu Leu Val Trp Ile
          35                  40                  45

 aac acc ttt gct gga tgg atc gag gcc ttt ccc act agc tct gaa aag      192
 Asn Thr Phe Ala Gly Trp Ile Glu Ala Phe Pro Thr Ser Ser Glu Lys
      50                  55                  60

 gct aca gca gta att tat tcc ctt ctg aca gat ata att ccc tta cgt      240
 Ala Thr Ala Val Ile Tyr Ser Leu Leu Thr Asp Ile Ile Pro Leu Arg
  65                  70                  75                  80

 ggc ctc cct act tcc att caa tct gac aat ggt ctg gcc ttt att agt      288
 Gly Leu Pro Thr Ser Ile Gln Ser Asp Asn Gly Leu Ala Phe Ile Ser
                  85                  90                  95

 caa atc acc cag gca gtt tct cag gct ctt gat att cag tgg aaa ctt      336
 Gln Ile Thr Gln Ala Val Ser Gln Ala Leu Asp Ile Gln Trp Lys Leu
             100                 105                 110

 cat atc ccc tac cat cct caa tct cca gga aag gta gaa tgg atg aat      384
 His Ile Pro Tyr His Pro Gln Ser Pro Gly Lys Val Glu Trp Met Asn
         115                 120                 125

 ggt ctt tta aaa aca aac ctc acc aag ctc aac ctc caa ctt aaa aag      432
 Gly Leu Leu Lys Thr Asn Leu Thr Lys Leu Asn Leu Gln Leu Lys Lys
     130                 135                 140

 gac tgg aca tta ctt cta cca ctt gcc ctt ctt aga att aga gct tgc      480
 Asp Trp Thr Leu Leu Leu Pro Leu Ala Leu Leu Arg Ile Arg Ala Cys
 145                 150                 155                 160

 ctt cga tat gct ata ggg tac agt cca ttt aaa ctt tta tat gga tgc      528
 Leu Arg Tyr Ala Ile Gly Tyr Ser Pro Phe Lys Leu Leu Tyr Gly Cys
                 165                 170                 175

 act ttc ttg cac ggc ccc aac ctt gtt cca gac acc agc cct ctg ggc      576
 Thr Phe Leu His Gly Pro Asn Leu Val Pro Asp Thr Ser Pro Leu Gly
             180                 185                 190

 aat tat ctt cca gtc ctc cag cag gct aga cag gaa att cgc cag gct      624
 Asn Tyr Leu Pro Val Leu Gln Gln Ala Arg Gln Glu Ile Arg Gln Ala
         195                 200                 205

 gct aat ctt ctc ttg cct act cca gat tcc cag cca tat aaa gac acc      672
 Ala Asn Leu Leu Leu Pro Thr Pro Asp Ser Gln Pro Tyr Lys Asp Thr
     210                 215                 220

 tta gct gga cga tca gtt ctt gtt aag agt ctg acc cct caa act cta      720
 Leu Ala Gly Arg Ser Val Leu Val Lys Ser Leu Thr Pro Gln Thr Leu
 225                 230                 235                 240

 cag cct tgg tgg acc aga ccc tac cta gtc atc tat agc acc cca act      768
 Gln Pro Trp Trp Thr Arg Pro Tyr Leu Val Ile Tyr Ser Thr Pro Thr
                 245                 250                 255

 gcc gtc cat ctg cag gac cct ccc cat tag                              798
 Ala Val His Leu Gln Asp Pro Pro His 
             260                 265





      <210> 756
      <211> 447
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(447)

      <400> 756
  atg gtt ctc atc ctg cgt ttt ctg aca gtc att agg ggt acc aat atg      48
  Met Val Leu Ile Leu Arg Phe Leu Thr Val Ile Arg Gly Thr Asn Met
    1               5                  10                  15

 gaa gag gcc cgc ctg cac cca cgt gaa ata aac agc cat gtt gct cac       96
 Glu Glu Ala Arg Leu His Pro Arg Glu Ile Asn Ser His Val Ala His
              20                  25                  30

 aca aag cct gtt tgg tgg tct ctt cac acg gac acg cat gaa att tgg      144
 Thr Lys Pro Val Trp Trp Ser Leu His Thr Asp Thr His Glu Ile Trp
          35                  40                  45

 tgc tgt gac tca gat cgg ggg acc tcc ctt agg aga tca atc ccc tgt      192
 Cys Cys Asp Ser Asp Arg Gly Thr Ser Leu Arg Arg Ser Ile Pro Cys
      50                  55                  60

 cct cct gct ttt tgc tcc tgg cta aag act gat gct gcc cga tcg cct      240
 Pro Pro Ala Phe Cys Ser Trp Leu Lys Thr Asp Ala Ala Arg Ser Pro
  65                  70                  75                  80

 cgg aag ccc cta gac cat cac gga tgc cga gct tca gca atg caa gaa      288
 Arg Lys Pro Leu Asp His His Gly Cys Arg Ala Ser Ala Met Gln Glu
                  85                  90                  95

 tgg act cac gca gaa aat tgg tac aag gag tgg gac att gta aca aag      336
 Trp Thr His Ala Glu Asn Trp Tyr Lys Glu Trp Asp Ile Val Thr Lys
             100                 105                 110

 ata cct gaa aat gtt gaa gca gct ttg gaa ttt ggt aac agg cag agg      384
 Ile Pro Glu Asn Val Glu Ala Ala Leu Glu Phe Gly Asn Arg Gln Arg
         115                 120                 125

 ttg gaa gac tgt gga ggg ctc agc aga aga aag gaa gat gag gga aaa      432
 Leu Glu Asp Cys Gly Gly Leu Ser Arg Arg Lys Glu Asp Glu Gly Lys
     130                 135                 140

 ttt gga aat tcc tag                                                  447
 Phe Gly Asn Ser 
 145





      <210> 757
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 757
  atg gaa tat gtt agc agc cca aga tcc tct gtg gag agg acg gtg ctc      48
  Met Glu Tyr Val Ser Ser Pro Arg Ser Ser Val Glu Arg Thr Val Leu
    1               5                  10                  15

 acc ttg gtc aca gtg gat gcc gta ctt gcc ctc ggt gca ggt ctc gca       96
 Thr Leu Val Thr Val Asp Ala Val Leu Ala Leu Gly Ala Gly Leu Ala
              20                  25                  30

 ggc tgt gcc gct gaa gcc ctc ccc aca ctc aca cac acc tgt gcc att      144
 Gly Cys Ala Ala Glu Ala Leu Pro Thr Leu Thr His Thr Cys Ala Ile
          35                  40                  45

 cac tcc atc caa aca gat gcc att acc aaa gca gac att ctg ggc att      192
 His Ser Ile Gln Thr Asp Ala Ile Thr Lys Ala Asp Ile Leu Gly Ile
      50                  55                  60

 ccc tgg aca ggg ctg gca ttg ggg gcc aaa gaa gcc ggc aca gca ttc      240
 Pro Trp Thr Gly Leu Ala Leu Gly Ala Lys Glu Ala Gly Thr Ala Phe
  65                  70                  75                  80

 tct cgt ctg aaa cag aag gac aaa gct tga                              270
 Ser Arg Leu Lys Gln Lys Asp Lys Ala 
                  85





      <210> 758
      <211> 306
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(306)

      <400> 758
  atg ctc tta aca caa agc aag atc aag tgt tgt gtc ttc aac tta agt      48
  Met Leu Leu Thr Gln Ser Lys Ile Lys Cys Cys Val Phe Asn Leu Ser
    1               5                  10                  15

 gta ctc ttc ttt ggt ctt gtt agt tgt tac gag gtt tgt tcc ttg cct       96
 Val Leu Phe Phe Gly Leu Val Ser Cys Tyr Glu Val Cys Ser Leu Pro
              20                  25                  30

 gat ctg aac ttg aag cag cag ttt cag gtg gta aag tct gtt ctg tta      144
 Asp Leu Asn Leu Lys Gln Gln Phe Gln Val Val Lys Ser Val Leu Leu
          35                  40                  45

 cac ttc ata cta aag agc agc gac cat gca ttc tat gat ttt cta agc      192
 His Phe Ile Leu Lys Ser Ser Asp His Ala Phe Tyr Asp Phe Leu Ser
      50                  55                  60

 cca gca tca agt gaa gtc ttc tgc atg aat gcc tgt ggc aac atg tgt      240
 Pro Ala Ser Ser Glu Val Phe Cys Met Asn Ala Cys Gly Asn Met Cys
  65                  70                  75                  80

 ggc ttg ttg ttt cag agg aaa atc aac agg cta gcc tgg cta gaa cag      288
 Gly Leu Leu Phe Gln Arg Lys Ile Asn Arg Leu Ala Trp Leu Glu Gln
                  85                  90                  95

 aga gct ggg ctg aag tga                                              306
 Arg Ala Gly Leu Lys 
             100





      <210> 759
      <211> 144
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(144)

      <400> 759
  atg atc ttg ctc tct ctg agc ctg ctg aac aat acg gct ctc atg ttc      48
  Met Ile Leu Leu Ser Leu Ser Leu Leu Asn Asn Thr Ala Leu Met Phe
    1               5                  10                  15

 aag ctg ctg gaa ctc cag gtc ttc aaa gtg ttt gct ttc aac atc caa       96
 Lys Leu Leu Glu Leu Gln Val Phe Lys Val Phe Ala Phe Asn Ile Gln
              20                  25                  30

 cag gtc agc atc ctt tgg aga aaa gtg aat gaa aac aag aca cac tga      144
 Gln Val Ser Ile Leu Trp Arg Lys Val Asn Glu Asn Lys Thr His 
          35                  40                  45





      <210> 760
      <211> 1056
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1056)

      <400> 760
  atg agc cag cgt gtc cgg ccc att gcc ctt ttt tta agc cta ggc ttg      48
  Met Ser Gln Arg Val Arg Pro Ile Ala Leu Phe Leu Ser Leu Gly Leu
    1               5                  10                  15

 aag tcc atg ctg cca gtc ggg ttg cag tca cca ctc aca gct caa gat       96
 Lys Ser Met Leu Pro Val Gly Leu Gln Ser Pro Leu Thr Ala Gln Asp
              20                  25                  30

 gct cac tta ccc caa ctt cct gtg gca gta gta gag gct gtg cct gca      144
 Ala His Leu Pro Gln Leu Pro Val Ala Val Val Glu Ala Val Pro Ala
          35                  40                  45

 gtg gta agg gcc att gtg aca tat atc cag gcc aat tgc caa gga aag      192
 Val Val Arg Ala Ile Val Thr Tyr Ile Gln Ala Asn Cys Gln Gly Lys
      50                  55                  60

 att gtg aca ttt ggc tgg gcc cat cac cta gtt aat gtg act ctc ctt      240
 Ile Val Thr Phe Gly Trp Ala His His Leu Val Asn Val Thr Leu Leu
  65                  70                  75                  80

 ttc ttc ctg tgc cct gcc ctc agt gga gat tgt gac aaa ttt ctg ggc      288
 Phe Phe Leu Cys Pro Ala Leu Ser Gly Asp Cys Asp Lys Phe Leu Gly
                  85                  90                  95

 caa tca gct gtg caa tat gac tct gct ctt tcc tgg gcc ctg cta tcg      336
 Gln Ser Ala Val Gln Tyr Asp Ser Ala Leu Ser Trp Ala Leu Leu Ser
             100                 105                 110

 ggg agc att gtg aca tat tgc cag gct cag cac cta ggt gaa att gtg      384
 Gly Ser Ile Val Thr Tyr Cys Gln Ala Gln His Leu Gly Glu Ile Val
         115                 120                 125

 gca tat acc tgg gtc cag atc aca ggc aca atg atg act ctc tta cct      432
 Ala Tyr Thr Trp Val Gln Ile Thr Gly Thr Met Met Thr Leu Leu Pro
     130                 135                 140

 gga cac agc cag tgg ttt ggt gac tct caa acc atg att cag cag acc      480
 Gly His Ser Gln Trp Phe Gly Asp Ser Gln Thr Met Ile Gln Gln Thr
 145                 150                 155                 160

 tgt gag gct gtg agt tcc cta tca gaa cac aat ctg cag gtg ctt ttg      528
 Cys Glu Ala Val Ser Ser Leu Ser Glu His Asn Leu Gln Val Leu Leu
                 165                 170                 175

 ggc tgg caa cag gtc tat acc tcc ctg gga tgg cgc tcc cag aga aaa      576
 Gly Trp Gln Gln Val Tyr Thr Ser Leu Gly Trp Arg Ser Gln Arg Lys
             180                 185                 190

 ggg cat gct gcc att gtt gct gtt ttg cag cat tca gtg gtg ata act      624
 Gly His Ala Ala Ile Val Ala Val Leu Gln His Ser Val Val Ile Thr
         195                 200                 205

 tcc agt act gga aaa tct gag gtg act aga aac tgt agt gga cac cca      672
 Ser Ser Thr Gly Lys Ser Glu Val Thr Arg Asn Cys Ser Gly His Pro
     210                 215                 220

 gca tac tgc agc aga cct tca gaa gtg gtc gga ctg tta cac act gtg      720
 Ala Tyr Cys Ser Arg Pro Ser Glu Val Val Gly Leu Leu His Thr Val
 225                 230                 235                 240

 ctg tca gcc atc tca cgg cag ctg tct gag aag att ggt cct gat gca      768
 Leu Ser Ala Ile Ser Arg Gln Leu Ser Glu Lys Ile Gly Pro Asp Ala
                 245                 250                 255

 gcc aca gct gct gtg cac gga gca gga gct cct tgc aat ttg gtg tct      816
 Ala Thr Ala Ala Val His Gly Ala Gly Ala Pro Cys Asn Leu Val Ser
             260                 265                 270

 tct gtg aac aca tgg gag ttc atg gag cga gga tct gtt ctg ttg gta      864
 Ser Val Asn Thr Trp Glu Phe Met Glu Arg Gly Ser Val Leu Leu Val
         275                 280                 285

 aca ttg ctg gcc att gtg ttt gat aag gtt ccc aca aag cca aaa aca      912
 Thr Leu Leu Ala Ile Val Phe Asp Lys Val Pro Thr Lys Pro Lys Thr
     290                 295                 300

 gga gga agg agg gag aag aga ttc gat tct gag tct cct act ccc agg      960
 Gly Gly Arg Arg Glu Lys Arg Phe Asp Ser Glu Ser Pro Thr Pro Arg
 305                 310                 315                 320

 ttg tac gtg gag aag cca act gct gct cga ggt cgg caa cgt ggc cac     1008
 Leu Tyr Val Glu Lys Pro Thr Ala Ala Arg Gly Arg Gln Arg Gly His
                 325                 330                 335

 aac cgc tca gtc ttc gtc tct tca caa aat cag ccc cat tac ttc tga     1056
 Asn Arg Ser Val Phe Val Ser Ser Gln Asn Gln Pro His Tyr Phe 
             340                 345                 350





      <210> 761
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 761
  atg acc att gtg gtc atc tgc tca gtc cta gct tca tgt caa aga ggt      48
  Met Thr Ile Val Val Ile Cys Ser Val Leu Ala Ser Cys Gln Arg Gly
    1               5                  10                  15

 cct caa aca aca ggt ttc tgt gaa cat gac tca aag gtt aaa cat ttt       96
 Pro Gln Thr Thr Gly Phe Cys Glu His Asp Ser Lys Val Lys His Phe
              20                  25                  30

 agt tac ata cat aat tgt cag aaa ggc tct aac ggt caa att ctt gag      144
 Ser Tyr Ile His Asn Cys Gln Lys Gly Ser Asn Gly Gln Ile Leu Glu
          35                  40                  45

 gaa aat gat act gta gcg cag cca tca gcc agg agg act cat act gga      192
 Glu Asn Asp Thr Val Ala Gln Pro Ser Ala Arg Arg Thr His Thr Gly
      50                  55                  60

 gag agc cct tat acc tgt aat gac tgt gga aaa tcc ctc tct aag aat      240
 Glu Ser Pro Tyr Thr Cys Asn Asp Cys Gly Lys Ser Leu Ser Lys Asn
  65                  70                  75                  80

 tac aac ctg att gta cat caa aaa atc cac aca gga gag aaa tcc tat      288
 Tyr Asn Leu Ile Val His Gln Lys Ile His Thr Gly Glu Lys Ser Tyr
                  85                  90                  95

 aaa tgc aag aaa agt cat act gtg gaa ata cta ttc gaa tgt aat gaa      336
 Lys Cys Lys Lys Ser His Thr Val Glu Ile Leu Phe Glu Cys Asn Glu
             100                 105                 110

 tgt gaa aaa tcc ttt tct gat gtc tcc aac ctt att gtc cat ctg aga      384
 Cys Glu Lys Ser Phe Ser Asp Val Ser Asn Leu Ile Val His Leu Arg
         115                 120                 125

 att cac atg tga                                                      396
 Ile His Met 
     130





      <210> 762
      <211> 516
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(516)

      <400> 762
  atg gcg ctg ctc gcc ttg ctg ctg gtc gtg gcc cta ccg cgg gtg tgg      48
  Met Ala Leu Leu Ala Leu Leu Leu Val Val Ala Leu Pro Arg Val Trp
    1               5                  10                  15

 aca gac gcc aac ctg act gcg aga caa cga gat cca gag gac tcc cag       96
 Thr Asp Ala Asn Leu Thr Ala Arg Gln Arg Asp Pro Glu Asp Ser Gln
              20                  25                  30

 cgg acg gac gag ggt gac aat aga gtg tgg tgt cat gtt tgt gag aga      144
 Arg Thr Asp Glu Gly Asp Asn Arg Val Trp Cys His Val Cys Glu Arg
          35                  40                  45

 gaa aac act ttc gag tgc cag aac cca agg agg tgc aaa tgg aca gag      192
 Glu Asn Thr Phe Glu Cys Gln Asn Pro Arg Arg Cys Lys Trp Thr Glu
      50                  55                  60

 cca tac tgc gtt ata gcg gcc gtg acg atg gag aga ccc aag cca gag      240
 Pro Tyr Cys Val Ile Ala Ala Val Thr Met Glu Arg Pro Lys Pro Glu
  65                  70                  75                  80

 gag aag cgg ttt ctc ctg gaa gag ccc atg ccc ttc ttt tac ctc aag      288
 Glu Lys Arg Phe Leu Leu Glu Glu Pro Met Pro Phe Phe Tyr Leu Lys
                  85                  90                  95

 tgt tgt aaa att cgc tac tgc aat tta gag ggg cca cct atc aac tca      336
 Cys Cys Lys Ile Arg Tyr Cys Asn Leu Glu Gly Pro Pro Ile Asn Ser
             100                 105                 110

 tca gtg ttc aaa gaa tat gct ggg agc atg gtt ctg gcg gtg gag aag      384
 Ser Val Phe Lys Glu Tyr Ala Gly Ser Met Val Leu Ala Val Glu Lys
         115                 120                 125

 tca aag atc aag atg cca aca gac ttg atg tct ggt gaa ggc ctg ttc      432
 Ser Lys Ile Lys Met Pro Thr Asp Leu Met Ser Gly Glu Gly Leu Phe
     130                 135                 140

 ctc ata gat ggc acc ttc tat gtg tct ctg gaa aga cct aaa gag gca      480
 Leu Ile Asp Gly Thr Phe Tyr Val Ser Leu Glu Arg Pro Lys Glu Ala
 145                 150                 155                 160

 aag aca ttc cct tca gtc tct ttc ata aag gca tga                      516
 Lys Thr Phe Pro Ser Val Ser Phe Ile Lys Ala 
                 165                 170





      <210> 763
      <211> 177
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(177)

      <400> 763
  atg gct gtc agc agc tac tgg gtg atg cca gga gcc tct gca atc atc      48
  Met Ala Val Ser Ser Tyr Trp Val Met Pro Gly Ala Ser Ala Ile Ile
    1               5                  10                  15

 tgc tta ttg cgc gtc acc gtc atc cag tgg gag agc ctt gtg gta cca       96
 Cys Leu Leu Arg Val Thr Val Ile Gln Trp Glu Ser Leu Val Val Pro
              20                  25                  30

 cct ttc tcc acc tat ggc tgc ggc cgc agg aag atg acg gtg atg aag      144
 Pro Phe Ser Thr Tyr Gly Cys Gly Arg Arg Lys Met Thr Val Met Lys
          35                  40                  45

 gct cgt gga cgg acc acg gtt cac tcg gtc tag                          177
 Ala Arg Gly Arg Thr Thr Val His Ser Val 
      50                  55





      <210> 764
      <211> 1047
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1047)

      <400> 764
  atg tca cag gat tta ctc tgg cca act ctg tgt gtc ttg gga act gta      48
  Met Ser Gln Asp Leu Leu Trp Pro Thr Leu Cys Val Leu Gly Thr Val
    1               5                  10                  15

 ctt tca cgt ttc att ccc tgt tgt tct tgt ctg tat ttt caa gcc aga       96
 Leu Ser Arg Phe Ile Pro Cys Cys Ser Cys Leu Tyr Phe Gln Ala Arg
              20                  25                  30

 aca atc att ctg tca acg cac cac ttg gac gag gct gaa gtg ctg agt      144
 Thr Ile Ile Leu Ser Thr His His Leu Asp Glu Ala Glu Val Leu Ser
          35                  40                  45

 gac cgc atc gcc ttc ctg gag cag ggt ggg ctt agg tgc tgt ggg tcc      192
 Asp Arg Ile Ala Phe Leu Glu Gln Gly Gly Leu Arg Cys Cys Gly Ser
      50                  55                  60

 cca ttt tac ctc aag gaa gcc ttt ggc gat ggg tat cac ctc acg ctt      240
 Pro Phe Tyr Leu Lys Glu Ala Phe Gly Asp Gly Tyr His Leu Thr Leu
  65                  70                  75                  80

 acc aag aag aag agt cca aat tta aat gca aat gca gta tgt gac acc      288
 Thr Lys Lys Lys Ser Pro Asn Leu Asn Ala Asn Ala Val Cys Asp Thr
                  85                  90                  95

 atg gcc gtg aca gca atg atc caa tca cat ctc ccc gaa gcc tac ctc      336
 Met Ala Val Thr Ala Met Ile Gln Ser His Leu Pro Glu Ala Tyr Leu
             100                 105                 110

 aag gag gat att ggg gga gag ctt gtt tat gta ctt cct cca ttc agc      384
 Lys Glu Asp Ile Gly Gly Glu Leu Val Tyr Val Leu Pro Pro Phe Ser
         115                 120                 125

 acc aaa gtc tca ggg gcc tac ctg tca ctc cta cgg gca ctc gac aat      432
 Thr Lys Val Ser Gly Ala Tyr Leu Ser Leu Leu Arg Ala Leu Asp Asn
     130                 135                 140

 ggc atg ggt gac ctc aac atc ggg tgc tac ggc att tca gat acc acc      480
 Gly Met Gly Asp Leu Asn Ile Gly Cys Tyr Gly Ile Ser Asp Thr Thr
 145                 150                 155                 160

 gtg gag gag gtc ttt ctg aac ttg acc aaa gag tca caa aaa aat agt      528
 Val Glu Glu Val Phe Leu Asn Leu Thr Lys Glu Ser Gln Lys Asn Ser
                 165                 170                 175

 gct atg agt ctt gag cac tta aca caa aag aaa att ggg aat tcc aat      576
 Ala Met Ser Leu Glu His Leu Thr Gln Lys Lys Ile Gly Asn Ser Asn
             180                 185                 190

 gcc aat ggc atc tca act cct gac gat tta tct gtg agc agc agc aat      624
 Ala Asn Gly Ile Ser Thr Pro Asp Asp Leu Ser Val Ser Ser Ser Asn
         195                 200                 205

 ttc aca gac aga gat gac aaa atc ctg aca aga gga gag agg ctg gat      672
 Phe Thr Asp Arg Asp Asp Lys Ile Leu Thr Arg Gly Glu Arg Leu Asp
     210                 215                 220

 ggc ttt gga ctg ttg ctg aag aag atc atg gct ata ctc atc aag agg      720
 Gly Phe Gly Leu Leu Leu Lys Lys Ile Met Ala Ile Leu Ile Lys Arg
 225                 230                 235                 240

 ttc cac cac acc cgc agg aac tgg aaa ggt ctc att gct cag gtt atc      768
 Phe His His Thr Arg Arg Asn Trp Lys Gly Leu Ile Ala Gln Val Ile
                 245                 250                 255

 ctc ccc atc gtc ttt gtt acc act gcc atg ggc ctt ggc aca ctg aga      816
 Leu Pro Ile Val Phe Val Thr Thr Ala Met Gly Leu Gly Thr Leu Arg
             260                 265                 270

 aat tcc agc aac agt tat cca gag att cag atc tcc ccc tct ctt tat      864
 Asn Ser Ser Asn Ser Tyr Pro Glu Ile Gln Ile Ser Pro Ser Leu Tyr
         275                 280                 285

 ggt acc tcc gaa cag aca gcc ttc tat gca cag tgt tta aac aaa gac      912
 Gly Thr Ser Glu Gln Thr Ala Phe Tyr Ala Gln Cys Leu Asn Lys Asp
     290                 295                 300

 agt ctg gaa aaa tgg aac acc agt gga gaa ccc atc act aat ttt ggt      960
 Ser Leu Glu Lys Trp Asn Thr Ser Gly Glu Pro Ile Thr Asn Phe Gly
 305                 310                 315                 320

 gtt tgc tcc tgc tca gaa aat gtc cag gac caa ttt cca aag gta ggt     1008
 Val Cys Ser Cys Ser Glu Asn Val Gln Asp Gln Phe Pro Lys Val Gly
                 325                 330                 335

 aat tct atg atg gtc ttt gtg gaa acc aac cga aaa tga                 1047
 Asn Ser Met Met Val Phe Val Glu Thr Asn Arg Lys 
             340                 345





      <210> 765
      <211> 1413
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1413)

      <400> 765
  atg cgc cgc ctc ccg cgg gcc ctg ctg ctg cag ctg cgc ctc gcc ctg      48
  Met Arg Arg Leu Pro Arg Ala Leu Leu Leu Gln Leu Arg Leu Ala Leu
    1               5                  10                  15

 ctg gtg gcc gcg ggg gcc ccg gag gtg ctg gtc agc gcg ccg cgg agc       96
 Leu Val Ala Ala Gly Ala Pro Glu Val Leu Val Ser Ala Pro Arg Ser
              20                  25                  30

 ctg gtg tgg ggg ccc ggg ctg cag gcg gcc gtc gtc ctg ccg gtc cgc      144
 Leu Val Trp Gly Pro Gly Leu Gln Ala Ala Val Val Leu Pro Val Arg
          35                  40                  45

 tat ttc tac ctg cag gcg gtc aac tcg gag ggc cag aac ctc act cgc      192
 Tyr Phe Tyr Leu Gln Ala Val Asn Ser Glu Gly Gln Asn Leu Thr Arg
      50                  55                  60

 tct ccc gca ggt gaa aca cca ttc aaa gtc gta gtc aaa tct ctt tca      240
 Ser Pro Ala Gly Glu Thr Pro Phe Lys Val Val Val Lys Ser Leu Ser
  65                  70                  75                  80

 cct aaa gag ttg gtc cgg ata cat gtc cct aaa cct ttg gac agg aat      288
 Pro Lys Glu Leu Val Arg Ile His Val Pro Lys Pro Leu Asp Arg Asn
                  85                  90                  95

 gat gga aca ttt ttg atg aga tat agg atg tat gaa act gtc gat gaa      336
 Asp Gly Thr Phe Leu Met Arg Tyr Arg Met Tyr Glu Thr Val Asp Glu
             100                 105                 110

 ggc ctg aag ata gag gtc ctt tat ggt gat gaa cat gtg gct cag tct      384
 Gly Leu Lys Ile Glu Val Leu Tyr Gly Asp Glu His Val Ala Gln Ser
         115                 120                 125

 ccc tat att ttg aaa gga cca gtg tac cat gag tac tgt gag tgt ccg      432
 Pro Tyr Ile Leu Lys Gly Pro Val Tyr His Glu Tyr Cys Glu Cys Pro
     130                 135                 140

 gaa gat cct cag gcc tgg cag aag act ctt tct tgt cca acc aag gaa      480
 Glu Asp Pro Gln Ala Trp Gln Lys Thr Leu Ser Cys Pro Thr Lys Glu
 145                 150                 155                 160

 cca cag att gca aaa gat ttt gct tcc ttt ccc agc atc aat ctc cag      528
 Pro Gln Ile Ala Lys Asp Phe Ala Ser Phe Pro Ser Ile Asn Leu Gln
                 165                 170                 175

 caa atg cta aaa gaa gtc ccc aaa agg ttt ggg gat gag aga ggt gcc      576
 Gln Met Leu Lys Glu Val Pro Lys Arg Phe Gly Asp Glu Arg Gly Ala
             180                 185                 190

 att gtt cat tac acg att ctc aat aac cat gtt tac cgg aga tct tta      624
 Ile Val His Tyr Thr Ile Leu Asn Asn His Val Tyr Arg Arg Ser Leu
         195                 200                 205

 ggg aaa tac aca gac ttc aag atg ttc tct gat gag att ttg tta tca      672
 Gly Lys Tyr Thr Asp Phe Lys Met Phe Ser Asp Glu Ile Leu Leu Ser
     210                 215                 220

 ttg aca aga aag tac aag tat caa gta aat gtg gat ggg acc gtg gct      720
 Leu Thr Arg Lys Tyr Lys Tyr Gln Val Asn Val Asp Gly Thr Val Ala
 225                 230                 235                 240

 gct tac aga tat cca tat ctc atg ctg ggc gac agt ctg gtt tta aag      768
 Ala Tyr Arg Tyr Pro Tyr Leu Met Leu Gly Asp Ser Leu Val Leu Lys
                 245                 250                 255

 cag gac tcg cca tat tat gaa cat ttc tac atg gca cta gaa cct tgg      816
 Gln Asp Ser Pro Tyr Tyr Glu His Phe Tyr Met Ala Leu Glu Pro Trp
             260                 265                 270

 aag cat tat gtt cca att aaa aga aat ctg agt gat tta tta gag aaa      864
 Lys His Tyr Val Pro Ile Lys Arg Asn Leu Ser Asp Leu Leu Glu Lys
         275                 280                 285

 gtt aaa tgg gct aag gaa aat gat gaa gaa gcc aag aag att gca aaa      912
 Val Lys Trp Ala Lys Glu Asn Asp Glu Glu Ala Lys Lys Ile Ala Lys
     290                 295                 300

 gaa gga cag ttg atg gct agg gac cta cta cag cca cac agg ctt tac      960
 Glu Gly Gln Leu Met Ala Arg Asp Leu Leu Gln Pro His Arg Leu Tyr
 305                 310                 315                 320

 tgc tac tat tac caa gta ctg cag atg cgt act gca act att aac cga     1008
 Cys Tyr Tyr Tyr Gln Val Leu Gln Met Arg Thr Ala Thr Ile Asn Arg
                 325                 330                 335

 aca ttg tta tta tca ttt gga aga atg gat aga gcc agt ttc act agt     1056
 Thr Leu Leu Leu Ser Phe Gly Arg Met Asp Arg Ala Ser Phe Thr Ser
             340                 345                 350

 gga ctc aaa cac act aat gag tac tgt tgc aaa ttc ctg tat cca gag     1104
 Gly Leu Lys His Thr Asn Glu Tyr Cys Cys Lys Phe Leu Tyr Pro Glu
         355                 360                 365

 cta tgt tgc tgc agc tgt tta gaa ccc aga aca atc ccc aca tca cca     1152
 Leu Cys Cys Cys Ser Cys Leu Glu Pro Arg Thr Ile Pro Thr Ser Pro
     370                 375                 380

 tca cgg agt tat gca caa tgc cac agg aca gct acc gtg gct ttt gct     1200
 Ser Arg Ser Tyr Ala Gln Cys His Arg Thr Ala Thr Val Ala Phe Ala
 385                 390                 395                 400

 ggc att cat cct aat gga tat tca gat gtt cct ctt cca gga tca tca     1248
 Gly Ile His Pro Asn Gly Tyr Ser Asp Val Pro Leu Pro Gly Ser Ser
                 405                 410                 415

 cgt ttt tca aac agc aag ttt aat caa gca cag aaa aac ata tat aac     1296
 Arg Phe Ser Asn Ser Lys Phe Asn Gln Ala Gln Lys Asn Ile Tyr Asn
             420                 425                 430

 tat gga gga gac ata tca aag atg caa atg gga ata cca gat gat act     1344
 Tyr Gly Gly Asp Ile Ser Lys Met Gln Met Gly Ile Pro Asp Asp Thr
         435                 440                 445

 tac tat gaa aat gtt tat caa gaa cca aat gta act aga tta acg cct     1392
 Tyr Tyr Glu Asn Val Tyr Gln Glu Pro Asn Val Thr Arg Leu Thr Pro
     450                 455                 460

 gat tct act tat gga cta taa                                         1413
 Asp Ser Thr Tyr Gly Leu 
 465                 470





      <210> 766
      <211> 354
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(354)

      <400> 766
  atg tcg gaa gtt ctc ccg ctc cag cgg gtc ctg gcc ctg ctg ctg gtg      48
  Met Ser Glu Val Leu Pro Leu Gln Arg Val Leu Ala Leu Leu Leu Val
    1               5                  10                  15

 gag cag agg cac ttc cct ggg ctc cag ccc cgt gat ggc ctg agg ccc       96
 Glu Gln Arg His Phe Pro Gly Leu Gln Pro Arg Asp Gly Leu Arg Pro
              20                  25                  30

 gtg ctc ctg ggt gtc gaa atg gac ctt ccg gac ctg gga gga aga agg      144
 Val Leu Leu Gly Val Glu Met Asp Leu Pro Asp Leu Gly Gly Arg Arg
          35                  40                  45

 gcc aat tac aag gtt gtg gta cgc acg aag cat tta gcc cag tac ctg      192
 Ala Asn Tyr Lys Val Val Val Arg Thr Lys His Leu Ala Gln Tyr Leu
      50                  55                  60

 gca cac gat tct tct gag ccc acc aac aaa gct cac cca ggt gag atg      240
 Ala His Asp Ser Ser Glu Pro Thr Asn Lys Ala His Pro Gly Glu Met
  65                  70                  75                  80

 ccc caa gct cag ctg ctc caa ctg acc ctt tca ggg gag cag ttt gaa      288
 Pro Gln Ala Gln Leu Leu Gln Leu Thr Leu Ser Gly Glu Gln Phe Glu
                  85                  90                  95

 gct ggg acg cag cat aaa ggg gat cat ggc aga gaa gag ctg act ggg      336
 Ala Gly Thr Gln His Lys Gly Asp His Gly Arg Glu Glu Leu Thr Gly
             100                 105                 110

 agg aca tca agt ctg tga                                              354
 Arg Thr Ser Ser Leu 
         115





      <210> 767
      <211> 483
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(483)

      <400> 767
  atg gcc ttc att ctc aga ctc ttc tgg cta aag cct cca gct gag agg      48
  Met Ala Phe Ile Leu Arg Leu Phe Trp Leu Lys Pro Pro Ala Glu Arg
    1               5                  10                  15

 cag aga aag gcc aca agc agt gac ggt caa ggc agc tgg gtc cca ccc       96
 Gln Arg Lys Ala Thr Ser Ser Asp Gly Gln Gly Ser Trp Val Pro Pro
              20                  25                  30

 cct cct cta acc agc agc agt tcc cag aat gcc tgg gca gaa cct gag      144
 Pro Pro Leu Thr Ser Ser Ser Ser Gln Asn Ala Trp Ala Glu Pro Glu
          35                  40                  45

 caa cac agg ctg ctt tgg aac ttg ctg cta agg cat gag gag gac ttg      192
 Gln His Arg Leu Leu Trp Asn Leu Leu Leu Arg His Glu Glu Asp Leu
      50                  55                  60

 gac tcc aag tct gca aag ggc gcc agg ctc gag tta gat ctg aac ggc      240
 Asp Ser Lys Ser Ala Lys Gly Ala Arg Leu Glu Leu Asp Leu Asn Gly
  65                  70                  75                  80

 gtc caa tct gct gga acc cat tat cga ctc tcg ccg acc cgc tgt ccg      288
 Val Gln Ser Ala Gly Thr His Tyr Arg Leu Ser Pro Thr Arg Cys Pro
                  85                  90                  95

 ccc ttg gag aaa cgt cga att ggc aga tct ata aaa gat ctg aag caa      336
 Pro Leu Glu Lys Arg Arg Ile Gly Arg Ser Ile Lys Asp Leu Lys Gln
             100                 105                 110

 ata tgc cac aat gtt aca ttt gtg aat tca gga tgg gct gcc cca ctg      384
 Ile Cys His Asn Val Thr Phe Val Asn Ser Gly Trp Ala Ala Pro Leu
         115                 120                 125

 ttc cca gca ggc cag gag tgt gac ttc acg gtg aag cgt cac gtc caa      432
 Phe Pro Ala Gly Gln Glu Cys Asp Phe Thr Val Lys Arg His Val Gln
     130                 135                 140

 gtt act ctg tac gtg gca atg cca gct acc cac aag aaa gga ggg ctg      480
 Val Thr Leu Tyr Val Ala Met Pro Ala Thr His Lys Lys Gly Gly Leu
 145                 150                 155                 160

 tga                                                                  483
 






      <210> 768
      <211> 1188
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1188)

      <400> 768
  atg gct gct cgc ctg gct tgg cgt gcc ttc tcc tcc cgg gcc ttc ctc      48
  Met Ala Ala Arg Leu Ala Trp Arg Ala Phe Ser Ser Arg Ala Phe Leu
    1               5                  10                  15

 ctg gct gcc tct ttc tgc tgg tgc agg tcc aag agg gtc ccc tcg cct       96
 Leu Ala Ala Ser Phe Cys Trp Cys Arg Ser Lys Arg Val Pro Ser Pro
              20                  25                  30

 gac cgc tgc cgc tgc tcc tgc caa aga agc cgg tgc cat gtg gcg ttt      144
 Asp Arg Cys Arg Cys Ser Cys Gln Arg Ser Arg Cys His Val Ala Phe
          35                  40                  45

 aca tct gga aga cgg aat cca gac cca gac cag agc gac ctg agc agg      192
 Thr Ser Gly Arg Arg Asn Pro Asp Pro Asp Gln Ser Asp Leu Ser Arg
      50                  55                  60

 gtc tcg gac tcg ggc agt cat tcc ggc agc gac agc cat tca ggg gcc      240
 Val Ser Asp Ser Gly Ser His Ser Gly Ser Asp Ser His Ser Gly Ala
  65                  70                  75                  80

 agc cgg gag ccg ggt gac ctg gca gaa agg gtc gag gtg gtg gcc ctg      288
 Ser Arg Glu Pro Gly Asp Leu Ala Glu Arg Val Glu Val Val Ala Leu
                  85                  90                  95

 agt gac tgt cag cag gag ttg agc ttg gtg agg act gtg act cgg gga      336
 Ser Asp Cys Gln Gln Glu Leu Ser Leu Val Arg Thr Val Thr Arg Gly
             100                 105                 110

 cca cgc gcc ttc ctg agc cgc gag gag gca cag cac ttc atc aaa gcg      384
 Pro Arg Ala Phe Leu Ser Arg Glu Glu Ala Gln His Phe Ile Lys Ala
         115                 120                 125

 tgt gga ctg ctc aac tgt gag gcc gtg ctg cag ctg ctg acc tgc cac      432
 Cys Gly Leu Leu Asn Cys Glu Ala Val Leu Gln Leu Leu Thr Cys His
     130                 135                 140

 ctg cgt ggg acc agt gaa tgc acg cag ctg agg gcg ctg tgt gcc atc      480
 Leu Arg Gly Thr Ser Glu Cys Thr Gln Leu Arg Ala Leu Cys Ala Ile
 145                 150                 155                 160

 gcc tcc ctg ggg agc agc gac ctc ctc ccc cag gag cac atc ctc ctc      528
 Ala Ser Leu Gly Ser Ser Asp Leu Leu Pro Gln Glu His Ile Leu Leu
                 165                 170                 175

 cgc acc cgg ccg tgg ctg cag gag ctc agc atg ggc agc ccg gga cct      576
 Arg Thr Arg Pro Trp Leu Gln Glu Leu Ser Met Gly Ser Pro Gly Pro
             180                 185                 190

 gtg acc aac aag gcc acc aag gtg ggc agc tgc gga ggc cac acg cca      624
 Val Thr Asn Lys Ala Thr Lys Val Gly Ser Cys Gly Gly His Thr Pro
         195                 200                 205

 cac cgg ggt cca agg atc ctg agg cac ttt gag gcc tcc tgt ggg cag      672
 His Arg Gly Pro Arg Ile Leu Arg His Phe Glu Ala Ser Cys Gly Gln
     210                 215                 220

 ctg tcc cct gcc cgg ggc acc tca gct gag cct ggc ccc aca gcc gcc      720
 Leu Ser Pro Ala Arg Gly Thr Ser Ala Glu Pro Gly Pro Thr Ala Ala
 225                 230                 235                 240

 ctc cca ggc cca tct gac ctg ctg acc gac gct gtg cct ctc cct ggg      768
 Leu Pro Gly Pro Ser Asp Leu Leu Thr Asp Ala Val Pro Leu Pro Gly
                 245                 250                 255

 agc cag gtc ttc ctg cag cct ctg agt tca acc ccg gtc tcg tcc cgg      816
 Ser Gln Val Phe Leu Gln Pro Leu Ser Ser Thr Pro Val Ser Ser Arg
             260                 265                 270

 agc cct gct ccc tca tct ggg atg ccg tcc agc cct gtg ccc acc cca      864
 Ser Pro Ala Pro Ser Ser Gly Met Pro Ser Ser Pro Val Pro Thr Pro
         275                 280                 285

 ccc cca gat gcc tcc ccc att cca gcc ccc gga gac ccc agc gag gcc      912
 Pro Pro Asp Ala Ser Pro Ile Pro Ala Pro Gly Asp Pro Ser Glu Ala
     290                 295                 300

 gag gcc aga ctg gca gaa agc agg cgg tgg aga cct gaa cgg atc cca      960
 Glu Ala Arg Leu Ala Glu Ser Arg Arg Trp Arg Pro Glu Arg Ile Pro
 305                 310                 315                 320

 ggg ggc acg gac agc cca aag aga ggc ccc agc agc tgt gcg tgg agc     1008
 Gly Gly Thr Asp Ser Pro Lys Arg Gly Pro Ser Ser Cys Ala Trp Ser
                 325                 330                 335

 cgc gac tcc ttg ttt gct ggc atg gag ctg gtg gcc tgt ccc cgc ctg     1056
 Arg Asp Ser Leu Phe Ala Gly Met Glu Leu Val Ala Cys Pro Arg Leu
             340                 345                 350

 gtg ggg gct ggg gct gct gcg gga gag tcc tgt cct gat gct ccc cgc     1104
 Val Gly Ala Gly Ala Ala Ala Gly Glu Ser Cys Pro Asp Ala Pro Arg
         355                 360                 365

 gcc ccc caa aca tcg tcc cag agg aca gca gcc aaa gag cct cct ggc     1152
 Ala Pro Gln Thr Ser Ser Gln Arg Thr Ala Ala Lys Glu Pro Pro Gly
     370                 375                 380

 tca gag ccg tca gct ttc gcg ttc ctg aac gcc tga                     1188
 Ser Glu Pro Ser Ala Phe Ala Phe Leu Asn Ala 
 385                 390                 395





      <210> 769
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 769
  atg agg gct ctc ctc ccc cgg acc ctg ctg tca tgg gtg gtg cag agc      48
  Met Arg Ala Leu Leu Pro Arg Thr Leu Leu Ser Trp Val Val Gln Ser
    1               5                  10                  15

 tgg aaa aat tcc tgc agt gga caa ctc agt gtg ctg gca ttg ctg gct       96
 Trp Lys Asn Ser Cys Ser Gly Gln Leu Ser Val Leu Ala Leu Leu Ala
              20                  25                  30

 gtg cag gtt gat tct cat cct ctt aga cag agt ggg aag gca gca ggc      144
 Val Gln Val Asp Ser His Pro Leu Arg Gln Ser Gly Lys Ala Ala Gly
          35                  40                  45

 tta gag ggc agg ggc cca gga acc ttc ggt aca cag ttg gtg gtt gaa      192
 Leu Glu Gly Arg Gly Pro Gly Thr Phe Gly Thr Gln Leu Val Val Glu
      50                  55                  60

 gct ttg gag ggc cag gga ctc agg gag cag ccc tca tcc cag gac cct      240
 Ala Leu Glu Gly Gln Gly Leu Arg Glu Gln Pro Ser Ser Gln Asp Pro
  65                  70                  75                  80

 cag tcc cca gat ggg cgg gat tgg tca ccg cag aac ctc agc agc tct      288
 Gln Ser Pro Asp Gly Arg Asp Trp Ser Pro Gln Asn Leu Ser Ser Ser
                  85                  90                  95

 tgg gct gca ctg ctc aat gga act ttc tgt gtg gat tga                  327
 Trp Ala Ala Leu Leu Asn Gly Thr Phe Cys Val Asp 
             100                 105





      <210> 770
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 770
  atg ctg ctt aaa ata aga tct gaa ggg gtg agc cag gtc ctc ctg gtc      48
  Met Leu Leu Lys Ile Arg Ser Glu Gly Val Ser Gln Val Leu Leu Val
    1               5                  10                  15

 ctt atg gtt ctc cag gag ctc ctg gaa ttg gac agc aag gta tta agg       96
 Leu Met Val Leu Gln Glu Leu Leu Glu Leu Asp Ser Lys Val Leu Arg
              20                  25                  30

 gag aaa gag gcc aag aag gaa gac cgg gag ctc cag gac cca ttg gag      144
 Glu Lys Glu Ala Lys Lys Glu Asp Arg Glu Leu Gln Asp Pro Leu Glu
          35                  40                  45

 ttg gtg agc ctg gac agc cag taa                                      168
 Leu Val Ser Leu Asp Ser Gln 
      50                  55





      <210> 771
      <211> 951
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(951)

      <400> 771
  atg agg aag gag tgg tca tta atg ttg tac aac agc cta ata tgc atc      48
  Met Arg Lys Glu Trp Ser Leu Met Leu Tyr Asn Ser Leu Ile Cys Ile
    1               5                  10                  15

 atc cca ttt ggc ctc atg aca gcc tcc ata agg agg tat cac acg tgt       96
 Ile Pro Phe Gly Leu Met Thr Ala Ser Ile Arg Arg Tyr His Thr Cys
              20                  25                  30

 gct aca gat gga gaa cca gac tcg agt gtg ctt gtc gga ggg gat ggt      144
 Ala Thr Asp Gly Glu Pro Asp Ser Ser Val Leu Val Gly Gly Asp Gly
          35                  40                  45

 gac ctg acc ctg ctg gtg gca gcc ctg ggt ttg gac ctg ggt ctg ccc      192
 Asp Leu Thr Leu Leu Val Ala Ala Leu Gly Leu Asp Leu Gly Leu Pro
      50                  55                  60

 ttc atg ctg ctg ccg ccc ctc atg gag tgg atg cgc gtg gcc atc acc      240
 Phe Met Leu Leu Pro Pro Leu Met Glu Trp Met Arg Val Ala Ile Thr
  65                  70                  75                  80

 tac gca gag cac cgc cgc agc ctc acc gtg gac agc ggc gac atc cgg      288
 Tyr Ala Glu His Arg Arg Ser Leu Thr Val Asp Ser Gly Asp Ile Arg
                  85                  90                  95

 cag gca gcc cgg ctg ctg ctg cct ggt ctg gac tgt gaa cct cgg cag      336
 Gln Ala Ala Arg Leu Leu Leu Pro Gly Leu Asp Cys Glu Pro Arg Gln
             100                 105                 110

 ctc aag ctg gat gcc cga gca gct act gaa aaa ttc aac cag gac ctg      384
 Leu Lys Leu Asp Ala Arg Ala Ala Thr Glu Lys Phe Asn Gln Asp Leu
         115                 120                 125

 ggt ttc cgc atg ctc aac tgt ggg agg acg gac ctc atc aac caa gcc      432
 Gly Phe Arg Met Leu Asn Cys Gly Arg Thr Asp Leu Ile Asn Gln Ala
     130                 135                 140

 atc gag gcc ttg ggt ccg gat ggg gtt aac acc atg gat gac cag ggt      480
 Ile Glu Ala Leu Gly Pro Asp Gly Val Asn Thr Met Asp Asp Gln Gly
 145                 150                 155                 160

 atg acg cca ctg atg tac gcc tgc gct gct ggg gac gaa gcg atg gtc      528
 Met Thr Pro Leu Met Tyr Ala Cys Ala Ala Gly Asp Glu Ala Met Val
                 165                 170                 175

 cag atg ttg att gat gct ggg gca aac ttg gac atc cag gtt cca agc      576
 Gln Met Leu Ile Asp Ala Gly Ala Asn Leu Asp Ile Gln Val Pro Ser
             180                 185                 190

 aac tcc ccc agg cac cct tcc atc cac ccc gac agc cgg cac tgg acc      624
 Asn Ser Pro Arg His Pro Ser Ile His Pro Asp Ser Arg His Trp Thr
         195                 200                 205

 tca ctg aca ttc gct gtg ctg cat gga cac atc tct gtg gtc cag ttg      672
 Ser Leu Thr Phe Ala Val Leu His Gly His Ile Ser Val Val Gln Leu
     210                 215                 220

 ctg ctg gat gct ggt gcc cat gtc gag ggc tcg gca gtg aac ggc ggc      720
 Leu Leu Asp Ala Gly Ala His Val Glu Gly Ser Ala Val Asn Gly Gly
 225                 230                 235                 240

 gag gac agc tat gcg gag acg ccc ctg cag ctg gcc tct gcg gca ggg      768
 Glu Asp Ser Tyr Ala Glu Thr Pro Leu Gln Leu Ala Ser Ala Ala Gly
                 245                 250                 255

 aac tat gag ctg gtc agt ttg ttg ctg agc cga ggc gcc gac ccc ctc      816
 Asn Tyr Glu Leu Val Ser Leu Leu Leu Ser Arg Gly Ala Asp Pro Leu
             260                 265                 270

 ctc agc atg ctg gag gcc cac ggc atg ggc tcc tcc ctc cac gag gac      864
 Leu Ser Met Leu Glu Ala His Gly Met Gly Ser Ser Leu His Glu Asp
         275                 280                 285

 atg aac tgc ttc agc cac tca gct gcc cac ggc cac agg tac ctg ccc      912
 Met Asn Cys Phe Ser His Ser Ala Ala His Gly His Arg Tyr Leu Pro
     290                 295                 300

 ggg att ccc acc ctg tgt gac atg agg gca ctg aac taa                  951
 Gly Ile Pro Thr Leu Cys Asp Met Arg Ala Leu Asn 
 305                 310                 315





      <210> 772
      <211> 276
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(276)

      <400> 772
  atg gct gtc tac gtc ggg atg ctg cgc ctg ggg agg ctg tgc gcc ggg      48
  Met Ala Val Tyr Val Gly Met Leu Arg Leu Gly Arg Leu Cys Ala Gly
    1               5                  10                  15

 agc tcg ggg gtg ctg ggg gcc cgg gcc gcc ctc tct cgg agt tgg cag       96
 Ser Ser Gly Val Leu Gly Ala Arg Ala Ala Leu Ser Arg Ser Trp Gln
              20                  25                  30

 gaa gcc agg ttg cag ggt gtc cgc ttc ctc aga act cct cac gac caa      144
 Glu Ala Arg Leu Gln Gly Val Arg Phe Leu Arg Thr Pro His Asp Gln
          35                  40                  45

 ctc ctt ccc cct atc tat gtg cct cct tcc cca aag aag gtg gat ggc      192
 Leu Leu Pro Pro Ile Tyr Val Pro Pro Ser Pro Lys Lys Val Asp Gly
      50                  55                  60

 tta gtc tgg ggc ttc agt gaa cct cca agg aag gaa ttc aag gag aaa      240
 Leu Val Trp Gly Phe Ser Glu Pro Pro Arg Lys Glu Phe Lys Glu Lys
  65                  70                  75                  80

 cct ggg ctg agc agg ctt ccc cca gac ctg ccc taa                      276
 Pro Gly Leu Ser Arg Leu Pro Pro Asp Leu Pro 
                  85                  90





      <210> 773
      <211> 600
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(600)

      <400> 773
  atg tac ctg aag ctc tgc cac ctc aac att ttc atc ctg atg gtc cta      48
  Met Tyr Leu Lys Leu Cys His Leu Asn Ile Phe Ile Leu Met Val Leu
    1               5                  10                  15

 agt agg ggg gtg cga gta gcc atc cat aca ttg att gtt tac ttg tca       96
 Ser Arg Gly Val Arg Val Ala Ile His Thr Leu Ile Val Tyr Leu Ser
              20                  25                  30

 gtc tca ttc aat ttc tgt tgc ttt caa gaa ccc cag ctg ctg ggt ata      144
 Val Ser Phe Asn Phe Cys Cys Phe Gln Glu Pro Gln Leu Leu Gly Ile
          35                  40                  45

 gca aca gaa gga gct gag tct ccc cag aag agg aag ttt gat aga ttc      192
 Ala Thr Glu Gly Ala Glu Ser Pro Gln Lys Arg Lys Phe Asp Arg Phe
      50                  55                  60

 cca gaa gtg gaa ttg ctt ggt caa acg ata gtg ttg gcc att acc att      240
 Pro Glu Val Glu Leu Leu Gly Gln Thr Ile Val Leu Ala Ile Thr Ile
  65                  70                  75                  80

 ttc tgc tac ctc aca ttg agt tac agc agc aac aac atc ttg gca gta      288
 Phe Cys Tyr Leu Thr Leu Ser Tyr Ser Ser Asn Asn Ile Leu Ala Val
                  85                  90                  95

 aaa cac tgt ttt gag tac ttc att gct ttt tac tgt tgt ttc aga aag      336
 Lys His Cys Phe Glu Tyr Phe Ile Ala Phe Tyr Cys Cys Phe Arg Lys
             100                 105                 110

 caa ctg agc gat tct ctg aca gaa cat cgt gga ttg aga gga aat aag      384
 Gln Leu Ser Asp Ser Leu Thr Glu His Arg Gly Leu Arg Gly Asn Lys
         115                 120                 125

 aat ggg tgt gcc tgc ttt agg att aca cag tgc tgg acc ttt gag gaa      432
 Asn Gly Cys Ala Cys Phe Arg Ile Thr Gln Cys Trp Thr Phe Glu Glu
     130                 135                 140

 gga gaa gca gag atg gat aga att gtt gtg gca gaa ctg agc ttg tat      480
 Gly Glu Ala Glu Met Asp Arg Ile Val Val Ala Glu Leu Ser Leu Tyr
 145                 150                 155                 160

 act tgg tcc tgt gga ggg tat cta ctc ttc ttc cag ctg cgg gtg agg      528
 Thr Trp Ser Cys Gly Gly Tyr Leu Leu Phe Phe Gln Leu Arg Val Arg
                 165                 170                 175

 agg aat ggt atg aag tat atc ttc aat agc tta gct ggt aag aaa cat      576
 Arg Asn Gly Met Lys Tyr Ile Phe Asn Ser Leu Ala Gly Lys Lys His
             180                 185                 190

 cac act gac ttc ctc ctt cag tga                                      600
 His Thr Asp Phe Leu Leu Gln 
         195





      <210> 774
      <211> 153
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(153)

      <400> 774
  atg ctc aaa tgt gcc ctt agg gca gcc tcg cat gct ctg aaa ggc atg      48
  Met Leu Lys Cys Ala Leu Arg Ala Ala Ser His Ala Leu Lys Gly Met
    1               5                  10                  15

 ctg gct ctc ttc cac ttc cac ctt cca cca tgg gat gac gca gta aga       96
 Leu Ala Leu Phe His Phe His Leu Pro Pro Trp Asp Asp Ala Val Arg
              20                  25                  30

 agg cca tca gta gat gcc agt ccc tca acc ttg aac ttt cca gac gca      144
 Arg Pro Ser Val Asp Ala Ser Pro Ser Thr Leu Asn Phe Pro Asp Ala
          35                  40                  45

 gaa ctg taa                                                          153
 Glu Leu 
      50





      <210> 775
      <211> 438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(438)

      <400> 775
  atg gag att ccg ctg atg ttc aga agc tct gcg ctg cag gtc tcg gtg      48
  Met Glu Ile Pro Leu Met Phe Arg Ser Ser Ala Leu Gln Val Ser Val
    1               5                  10                  15

 tcc ctt ctg ctc ccg ctg tct cag cct cgc gat gtc acc ctc ttc gtc       96
 Ser Leu Leu Leu Pro Leu Ser Gln Pro Arg Asp Val Thr Leu Phe Val
              20                  25                  30

 tcc ctc ttc ggt gtt cgg ggt ccc aga aac cga gtt atc aca gtg gcc      144
 Ser Leu Phe Gly Val Arg Gly Pro Arg Asn Arg Val Ile Thr Val Ala
          35                  40                  45

 cgg acc acg ggg aaa ttg ctg aat cat cct gtt ggg atc acc gag cct      192
 Arg Thr Thr Gly Lys Leu Leu Asn His Pro Val Gly Ile Thr Glu Pro
      50                  55                  60

 gca ggc ata aag tgg gcc cat ggg gaa aat ata gct aaa atc tcc aat      240
 Ala Gly Ile Lys Trp Ala His Gly Glu Asn Ile Ala Lys Ile Ser Asn
  65                  70                  75                  80

 gaa gtg tct gct tat gaa gta aat aca ggt cct cct gtg gct ggc gaa      288
 Glu Val Ser Ala Tyr Glu Val Asn Thr Gly Pro Pro Val Ala Gly Glu
                  85                  90                  95

 ggt gag tcg agt ccc cgt ctt cag ttt gtc aaa gtg gac aaa gcc tac      336
 Gly Glu Ser Ser Pro Arg Leu Gln Phe Val Lys Val Asp Lys Ala Tyr
             100                 105                 110

 gac aat ggc cag tac cag cta cta ggc att ccc agt ctt tcc agt tgg      384
 Asp Asn Gly Gln Tyr Gln Leu Leu Gly Ile Pro Ser Leu Ser Ser Trp
         115                 120                 125

 tgg tac tgg agc ttc cct acc cag gat ttc cgt gga ttc caa ggg tac      432
 Trp Tyr Trp Ser Phe Pro Thr Gln Asp Phe Arg Gly Phe Gln Gly Tyr
     130                 135                 140

 aac tga                                                              438
 Asn 
 145





      <210> 776
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 776
  atg cgt gcg ctc cgc gac cga gcc ggg ctc ctc ctc tgc gtg ctg ctg      48
  Met Arg Ala Leu Arg Asp Arg Ala Gly Leu Leu Leu Cys Val Leu Leu
    1               5                  10                  15

 ctg gcg gcg ctg ctg gag gcg gcg cta ggg ctc ccc gtg aag aag ccg       96
 Leu Ala Ala Leu Leu Glu Ala Ala Leu Gly Leu Pro Val Lys Lys Pro
              20                  25                  30

 cgg ctc cgc gga cca cgg cct ggg agc ctc acg agg ctc gca gag acc      144
 Arg Leu Arg Gly Pro Arg Pro Gly Ser Leu Thr Arg Leu Ala Glu Thr
          35                  40                  45

 att cag tct cta aag ggt tgg aaa agc ccc cag gga ggg aga gag aga      192
 Ile Gln Ser Leu Lys Gly Trp Lys Ser Pro Gln Gly Gly Arg Glu Arg
      50                  55                  60

 agg aca gga atg agg cct gga agc ttg gct gcc cag agg cct cag gca      240
 Arg Thr Gly Met Arg Pro Gly Ser Leu Ala Ala Gln Arg Pro Gln Ala
  65                  70                  75                  80

 agt ctc cag cct ctc cga tct cag tct cag gtt gtt acg agg atc aaa      288
 Ser Leu Gln Pro Leu Arg Ser Gln Ser Gln Val Val Thr Arg Ile Lys
                  85                  90                  95

 ggg aag gat gga cgt gga gag ttg aac atc ctg tat agt gtt ttg ttc      336
 Gly Lys Asp Gly Arg Gly Glu Leu Asn Ile Leu Tyr Ser Val Leu Phe
             100                 105                 110

 atc cag cac att cag cac cgc aga gca gca ggc ggc aaa cca gaa gtg      384
 Ile Gln His Ile Gln His Arg Arg Ala Ala Gly Gly Lys Pro Glu Val
         115                 120                 125

 att tat cgg gct cct ata atg tat cag gca ctg tgc tca gca cag tat      432
 Ile Tyr Arg Ala Pro Ile Met Tyr Gln Ala Leu Cys Ser Ala Gln Tyr
     130                 135                 140

 ccc aca gtg aac aaa gca gac aca att cct gtc tgc aca gaa ctt acc      480
 Pro Thr Val Asn Lys Ala Asp Thr Ile Pro Val Cys Thr Glu Leu Thr
 145                 150                 155                 160

 ttt gag ttg gaa aaa gtg aca gat ggc atg gaa att gcc tag              522
 Phe Glu Leu Glu Lys Val Thr Asp Gly Met Glu Ile Ala 
                 165                 170





      <210> 777
      <211> 447
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(447)

      <400> 777
  atg ctg ctg ctc ctg ctg ctg ctg ctg ctg ctt ggc tgt ttt cat ctg      48
  Met Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Gly Cys Phe His Leu
    1               5                  10                  15

 ggc cag tgg aat gta agg gag aga tgg caa ttg agg tgc aaa agc tca       96
 Gly Gln Trp Asn Val Arg Glu Arg Trp Gln Leu Arg Cys Lys Ser Ser
              20                  25                  30

 tca aac acg atc tgt gga ggc aca gaa tta aag tat gtc gag agt gga      144
 Ser Asn Thr Ile Cys Gly Gly Thr Glu Leu Lys Tyr Val Glu Ser Gly
          35                  40                  45

 aag gat ctt tgc tat gag ctg ctc caa cct cta aga gcc gcc acc acc      192
 Lys Asp Leu Cys Tyr Glu Leu Leu Gln Pro Leu Arg Ala Ala Thr Thr
      50                  55                  60

 acc acc acc act gac aag aca gag cac acg ctc tgt gcc tgg aat tat      240
 Thr Thr Thr Thr Asp Lys Thr Glu His Thr Leu Cys Ala Trp Asn Tyr
  65                  70                  75                  80

 gac aga gat ggt tta att tca tgt aat tgt cag aac tgt gtg agg gag      288
 Asp Arg Asp Gly Leu Ile Ser Cys Asn Cys Gln Asn Cys Val Arg Glu
                  85                  90                  95

 gtc ttc act tca gaa atc caa gac tca tat tca tcc agc ttg gtg tca      336
 Val Phe Thr Ser Glu Ile Gln Asp Ser Tyr Ser Ser Ser Leu Val Ser
             100                 105                 110

 agt ggg ctg ttg ctg cca gaa tta tct tgt gat tat ttg aga gat gta      384
 Ser Gly Leu Leu Leu Pro Glu Leu Ser Cys Asp Tyr Leu Arg Asp Val
         115                 120                 125

 tca gtt tct tct gaa gta caa tca act gta gaa gcc ttt gta gca gaa      432
 Ser Val Ser Ser Glu Val Gln Ser Thr Val Glu Ala Phe Val Ala Glu
     130                 135                 140

 cat gct gtg tct taa                                                  447
 His Ala Val Ser 
 145





      <210> 778
      <211> 207
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(207)

      <400> 778
  atg gta tta gcc tgt gta aga gaa gtt ctt tac ctc tat cat tat gta      48
  Met Val Leu Ala Cys Val Arg Glu Val Leu Tyr Leu Tyr His Tyr Val
    1               5                  10                  15

 att atc aca ctg ttt gat tac tgt ggc ttt aag caa cat tac gaa gct       96
 Ile Ile Thr Leu Phe Asp Tyr Cys Gly Phe Lys Gln His Tyr Glu Ala
              20                  25                  30

 aat gtg gtt gtt ttt aaa aaa tct gca aaa ggg ttt cag gga acg gct      144
 Asn Val Val Val Phe Lys Lys Ser Ala Lys Gly Phe Gln Gly Thr Ala
          35                  40                  45

 ggt act tac gtt gtc tgc gtt gct gtg gat cct gaa agg tgt tct gtt      192
 Gly Thr Tyr Val Val Cys Val Ala Val Asp Pro Glu Arg Cys Ser Val
      50                  55                  60

 ggc acc ggg cgc tga                                                  207
 Gly Thr Gly Arg 
  65





      <210> 779
      <211> 837
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(837)

      <400> 779
  atg aat gaa gct acg ctg cga agg cag act gcg tgg ctg ctg gtc ccg      48
  Met Asn Glu Ala Thr Leu Arg Arg Gln Thr Ala Trp Leu Leu Val Pro
    1               5                  10                  15

 tgg ctg ctg gcc ccg cag cat gtc tgc cgc ctt ttc agc agg ctt gct       96
 Trp Leu Leu Ala Pro Gln His Val Cys Arg Leu Phe Ser Arg Leu Ala
              20                  25                  30

 gca tct cct cat tcc ctc acc ttt ctg gca gta agg agt tcc cac gtt      144
 Ala Ser Pro His Ser Leu Thr Phe Leu Ala Val Arg Ser Ser His Val
          35                  40                  45

 tgc ccc gct tca gtg tcg tgg act ggc aaa atg ctg tct cta aac ccc      192
 Cys Pro Ala Ser Val Ser Trp Thr Gly Lys Met Leu Ser Leu Asn Pro
      50                  55                  60

 tcc acg cct cag gta atc cgc tca ttt ctc aca cag acg cag ctg ttt      240
 Ser Thr Pro Gln Val Ile Arg Ser Phe Leu Thr Gln Thr Gln Leu Phe
  65                  70                  75                  80

 ccg agg aat gtc cgg ccg agc ccg cag ggt gcg ggc agc gag tat cct      288
 Pro Arg Asn Val Arg Pro Ser Pro Gln Gly Ala Gly Ser Glu Tyr Pro
                  85                  90                  95

 ggg acc ttc agg gga gga ggt ggc tcc cac acc cca ata ccg tac aga      336
 Gly Thr Phe Arg Gly Gly Gly Gly Ser His Thr Pro Ile Pro Tyr Arg
             100                 105                 110

 gag tcc gaa gag tcc ggg ccc tta ttt ttc caa ttc ttg gta aac aac      384
 Glu Ser Glu Glu Ser Gly Pro Leu Phe Phe Gln Phe Leu Val Asn Asn
         115                 120                 125

 aaa cat gct cgc cct cgc ctt ccc gtg cag acg cct cag ggc caa ctc      432
 Lys His Ala Arg Pro Arg Leu Pro Val Gln Thr Pro Gln Gly Gln Leu
     130                 135                 140

 ggg ctt cgc cag gca ccg aga gca gac aga aga cac caa atg gct att      480
 Gly Leu Arg Gln Ala Pro Arg Ala Asp Arg Arg His Gln Met Ala Ile
 145                 150                 155                 160

 acc aag aga gag ggg cga ggg cac ccg cgc cgg cgt ata acg ctt gcc      528
 Thr Lys Arg Glu Gly Arg Gly His Pro Arg Arg Arg Ile Thr Leu Ala
                 165                 170                 175

 ctt ttc ccc gcg ctc ggt cgg ccc gac gcc tca agc gcc aag gtt gct      576
 Leu Phe Pro Ala Leu Gly Arg Pro Asp Ala Ser Ser Ala Lys Val Ala
             180                 185                 190

 ttg caa tgg ctg gag gca gct acc aac gac ttt ctt cac aga att gga      624
 Leu Gln Trp Leu Glu Ala Ala Thr Asn Asp Phe Leu His Arg Ile Gly
         195                 200                 205

 aaa aac tac ttt aaa gtt cat atg gaa cca aaa aag agc cct cat tgc      672
 Lys Asn Tyr Phe Lys Val His Met Glu Pro Lys Lys Ser Pro His Cys
     210                 215                 220

 caa gac aat cct aag cca aag aac aaa gct gga ggc atc acg cta cct      720
 Gln Asp Asn Pro Lys Pro Lys Asn Lys Ala Gly Gly Ile Thr Leu Pro
 225                 230                 235                 240

 gac ttc aaa cta tac tac aag gct acg gta aca aaa aca gca agg ttc      768
 Asp Phe Lys Leu Tyr Tyr Lys Ala Thr Val Thr Lys Thr Ala Arg Phe
                 245                 250                 255

 ctt ctc tat aaa gta agt caa atc gac aat aca gac ctc ttt gat cct      816
 Leu Leu Tyr Lys Val Ser Gln Ile Asp Asn Thr Asp Leu Phe Asp Pro
             260                 265                 270

 gtg aag att aaa ttt gaa tga                                          837
 Val Lys Ile Lys Phe Glu 
         275





      <210> 780
      <211> 693
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(693)

      <400> 780
  atg ggc cgg ccg cgc tcc gcg ggg cgc ggg gcc tgg gaa ggc gcg ggg      48
  Met Gly Arg Pro Arg Ser Ala Gly Arg Gly Ala Trp Glu Gly Ala Gly
    1               5                  10                  15

 ccg gga gga gag ttc ggc gtt agc ctg tgc ctg tta caa ctc gct tct       96
 Pro Gly Gly Glu Phe Gly Val Ser Leu Cys Leu Leu Gln Leu Ala Ser
              20                  25                  30

 tgt atc cat ttc tgg tta gtc tta agt atc ttc ttg agg aca ttg tct      144
 Cys Ile His Phe Trp Leu Val Leu Ser Ile Phe Leu Arg Thr Leu Ser
          35                  40                  45

 aaa aag cag ctg cat gcc att gac att cag aca gaa cag ggc ccc ttg      192
 Lys Lys Gln Leu His Ala Ile Asp Ile Gln Thr Glu Gln Gly Pro Leu
      50                  55                  60

 gcc tta gaa ggt gta ggg gcc tta aat att ctg aag gtg act tca tgg      240
 Ala Leu Glu Gly Val Gly Ala Leu Asn Ile Leu Lys Val Thr Ser Trp
  65                  70                  75                  80

 agt ggc cgc cct ctg tgg tca ccc tac ctg tgc gtg gcc ctg tcc tgg      288
 Ser Gly Arg Pro Leu Trp Ser Pro Tyr Leu Cys Val Ala Leu Ser Trp
                  85                  90                  95

 cgt atc tgc cag ggg gac gcg ctg cag cag cct gaa gac tgc tgg gtt      336
 Arg Ile Cys Gln Gly Asp Ala Leu Gln Gln Pro Glu Asp Cys Trp Val
             100                 105                 110

 aaa ggc agt gtg gcc ggt gat ctg aca caa cag ggc ttg agt tac ttg      384
 Lys Gly Ser Val Ala Gly Asp Leu Thr Gln Gln Gly Leu Ser Tyr Leu
         115                 120                 125

 ccc gag gtt gtg tca cgg aac ggc agg gcc gcc ttt agg ctt aca tcc      432
 Pro Glu Val Val Ser Arg Asn Gly Arg Ala Ala Phe Arg Leu Thr Ser
     130                 135                 140

 ctg gaa ctc cca cct cca cag acc cgt ccg ggt gct gaa agt cca cgg      480
 Leu Glu Leu Pro Pro Pro Gln Thr Arg Pro Gly Ala Glu Ser Pro Arg
 145                 150                 155                 160

 atg cta tcc ctg gtc aaa tca gag gtg tgt gtt atc gga ggt ttc att      528
 Met Leu Ser Leu Val Lys Ser Glu Val Cys Val Ile Gly Gly Phe Ile
                 165                 170                 175

 cct gga aaa tcc agt gtc tat gaa acc aac ata cat ggc gtt tgc atc      576
 Pro Gly Lys Ser Ser Val Tyr Glu Thr Asn Ile His Gly Val Cys Ile
             180                 185                 190

 aca gtt gga gtc aga tgt gag ccc gga ggg cag gtg tct ggg gcc tgg      624
 Thr Val Gly Val Arg Cys Glu Pro Gly Gly Gln Val Ser Gly Ala Trp
         195                 200                 205

 ggc aac tgc tgg cca cca agc agt gtc cag tgt cat agc cgc tca ctt      672
 Gly Asn Cys Trp Pro Pro Ser Ser Val Gln Cys His Ser Arg Ser Leu
     210                 215                 220

 gtc ctg tgg ggc cac cca tga                                          693
 Val Leu Trp Gly His Pro 
 225                 230





      <210> 781
      <211> 501
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(501)

      <400> 781
  atg gaa agc tgc ttc ctg ctg tgg ctt gcg cag atg ctg gta gag tcc      48
  Met Glu Ser Cys Phe Leu Leu Trp Leu Ala Gln Met Leu Val Glu Ser
    1               5                  10                  15

 agc cat gca gct cgc gtg cac tca tca ctc cag agg cag cat cgc cgc       96
 Ser His Ala Ala Arg Val His Ser Ser Leu Gln Arg Gln His Arg Arg
              20                  25                  30

 aga atg cga gtt cac ctt tat agg gag tct gcc cag gtc acg cag cac      144
 Arg Met Arg Val His Leu Tyr Arg Glu Ser Ala Gln Val Thr Gln His
          35                  40                  45

 tgg ctc agg gta ccc acg gca gca aag cag ctg cac caa gat gcg gag      192
 Trp Leu Arg Val Pro Thr Ala Ala Lys Gln Leu His Gln Asp Ala Glu
      50                  55                  60

 cgc acc acg gtc act cag tac agc acg tgt gcg ctg ctt act gcc ctg      240
 Arg Thr Thr Val Thr Gln Tyr Ser Thr Cys Ala Leu Leu Thr Ala Leu
  65                  70                  75                  80

 tgc ctg ctg ctg cct gtg ctg cag gaa aca gcc cag agt cga agg atg      288
 Cys Leu Leu Leu Pro Val Leu Gln Glu Thr Ala Gln Ser Arg Arg Met
                  85                  90                  95

 gtc acc agc cac ccg gaa gac agt cct gct ctg gca cgc aaa cac gga      336
 Val Thr Ser His Pro Glu Asp Ser Pro Ala Leu Ala Arg Lys His Gly
             100                 105                 110

 gca tcg caa ccg gcc ggc ctc ggc ttt cca aga act cag act gtc act      384
 Ala Ser Gln Pro Ala Gly Leu Gly Phe Pro Arg Thr Gln Thr Val Thr
         115                 120                 125

 ccc gcc ttc aca ttc cag aac cca aca gca gct gag ccc gca ctt ctg      432
 Pro Ala Phe Thr Phe Gln Asn Pro Thr Ala Ala Glu Pro Ala Leu Leu
     130                 135                 140

 agc gcg tgg cta ggt aga gct cca gaa act gag aca atc aca gac atg      480
 Ser Ala Trp Leu Gly Arg Ala Pro Glu Thr Glu Thr Ile Thr Asp Met
 145                 150                 155                 160

 gca ggt gcg tca ggg cta tga                                          501
 Ala Gly Ala Ser Gly Leu 
                 165





      <210> 782
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(498)

      <400> 782
  atg aag aag ctt cac tct ggg aga acc ccc ttc gtg acc acg gtc tct      48
  Met Lys Lys Leu His Ser Gly Arg Thr Pro Phe Val Thr Thr Val Ser
    1               5                  10                  15

 ttc ctg cca gca tgc cct gtg gcc tgt atc ctg ctg gtg tgg aac agt       96
 Phe Leu Pro Ala Cys Pro Val Ala Cys Ile Leu Leu Val Trp Asn Ser
              20                  25                  30

 cag acc cct gca ggg ctg cag agc ctc tgt act ggg cgg cat ccc agc      144
 Gln Thr Pro Ala Gly Leu Gln Ser Leu Cys Thr Gly Arg His Pro Ser
          35                  40                  45

 ctg agt gcc aga gct cag tgg gca ggc ccc cga gca agc aga gag gag      192
 Leu Ser Ala Arg Ala Gln Trp Ala Gly Pro Arg Ala Ser Arg Glu Glu
      50                  55                  60

 ggc acc ttt tgg aca gaa cct gtg gga caa gag cga cgt ctc atc cgt      240
 Gly Thr Phe Trp Thr Glu Pro Val Gly Gln Glu Arg Arg Leu Ile Arg
  65                  70                  75                  80

 tca ggt tcc tca caa aat gag agt cag gaa gat cag ggt gca gac ctg      288
 Ser Gly Ser Ser Gln Asn Glu Ser Gln Glu Asp Gln Gly Ala Asp Leu
                  85                  90                  95

 att tcc cac gaa ggg ctg aaa gca gac aac cgg agg gag agc agc acc      336
 Ile Ser His Glu Gly Leu Lys Ala Asp Asn Arg Arg Glu Ser Ser Thr
             100                 105                 110

 tgg gcc aat gag gta gaa gac aga aga cca cag tgt act tct gcc ctc      384
 Trp Ala Asn Glu Val Glu Asp Arg Arg Pro Gln Cys Thr Ser Ala Leu
         115                 120                 125

 aac ctc acc ccc tcc cac cta cat cct cca cac ccc ctg acc acc ttc      432
 Asn Leu Thr Pro Ser His Leu His Pro Pro His Pro Leu Thr Thr Phe
     130                 135                 140

 ttc aga aac gta ata gga atc aag atc ccc cct ggc ctg gtt gct atg      480
 Phe Arg Asn Val Ile Gly Ile Lys Ile Pro Pro Gly Leu Val Ala Met
 145                 150                 155                 160

 gga ggc aca gtg gcc tga                                              498
 Gly Gly Thr Val Ala 
                 165





      <210> 783
      <211> 375
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(375)

      <400> 783
  atg ctc gtc agc cct gcg ccc gtg ccg ctg ccg ctg ctc gcc cag gcc      48
  Met Leu Val Ser Pro Ala Pro Val Pro Leu Pro Leu Leu Ala Gln Ala
    1               5                  10                  15

 gcc gcg ggc cct gcc ctg ctg ccc tcc ccg ggt ccc gcc gcc tcc ggg       96
 Ala Ala Gly Pro Ala Leu Leu Pro Ser Pro Gly Pro Ala Ala Ser Gly
              20                  25                  30

 gcc agt gcc aaa gcc ccc gtg cgc agc gtg gtg act gag acg gtc agc      144
 Ala Ser Ala Lys Ala Pro Val Arg Ser Val Val Thr Glu Thr Val Ser
          35                  40                  45

 acc tac gtg atc cga gat gag tgg ggc aat cag atc tgg atc tgc cct      192
 Thr Tyr Val Ile Arg Asp Glu Trp Gly Asn Gln Ile Trp Ile Cys Pro
      50                  55                  60

 ggg tgt aac aag cct gac gat ggg agt ccc atg att ggg tgt gac gac      240
 Gly Cys Asn Lys Pro Asp Asp Gly Ser Pro Met Ile Gly Cys Asp Asp
  65                  70                  75                  80

 tgc gat gac tgg tac cac tgg ccc tgt gtt gga atc atg act gca ccc      288
 Cys Asp Asp Trp Tyr His Trp Pro Cys Val Gly Ile Met Thr Ala Pro
                  85                  90                  95

 cca gaa gag atg cag tgg ttc tgc ccc aag tgt gcg aac aag aag aag      336
 Pro Glu Glu Met Gln Trp Phe Cys Pro Lys Cys Ala Asn Lys Lys Lys
             100                 105                 110

 gac aaa aag cac aag aag agg aag cat cga gcc cac tga                  375
 Asp Lys Lys His Lys Lys Arg Lys His Arg Ala His 
         115                 120





      <210> 784
      <211> 654
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(654)

      <400> 784
  atg gct gtg ttt ctg cag ctg cta ccg ctg ctg ctc tcg agg gcc caa      48
  Met Ala Val Phe Leu Gln Leu Leu Pro Leu Leu Leu Ser Arg Ala Gln
    1               5                  10                  15

 ggg aac cct ggg gct tct ctg gac ggc cgc cct ggg gac cgg gtg aat       96
 Gly Asn Pro Gly Ala Ser Leu Asp Gly Arg Pro Gly Asp Arg Val Asn
              20                  25                  30

 ctc tcc tgc gga gga gtc tct cat ccc atc cgc tgg gtc tgg gca ccc      144
 Leu Ser Cys Gly Gly Val Ser His Pro Ile Arg Trp Val Trp Ala Pro
          35                  40                  45

 agc ttc ccg gcc tgc aag ggc ctg tcc aaa gga cgc cga ccg atc ctg      192
 Ser Phe Pro Ala Cys Lys Gly Leu Ser Lys Gly Arg Arg Pro Ile Leu
      50                  55                  60

 tgg gcc tct tcg agc ggg acc ccc acc gtg cct ccc ctc cag cct ttc      240
 Trp Ala Ser Ser Ser Gly Thr Pro Thr Val Pro Pro Leu Gln Pro Phe
  65                  70                  75                  80

 gtc ggc cgc cta cgc tcc ctg gac tct ggt atc cgg cgg ctg gag ctc      288
 Val Gly Arg Leu Arg Ser Leu Asp Ser Gly Ile Arg Arg Leu Glu Leu
                  85                  90                  95

 ctc ttg agc gcg ggg gac tcg ggc act ttt ttc tgc aag ggc cgc cac      336
 Leu Leu Ser Ala Gly Asp Ser Gly Thr Phe Phe Cys Lys Gly Arg His
             100                 105                 110

 gag gac gag agc cgt aca gtg ctt cac gtg ctg ggg gac agg acc tat      384
 Glu Asp Glu Ser Arg Thr Val Leu His Val Leu Gly Asp Arg Thr Tyr
         115                 120                 125

 tgc aag gcc ccc ggg cct acc cat ggc gcc tgc ccc cgc aac cga ttc      432
 Cys Lys Ala Pro Gly Pro Thr His Gly Ala Cys Pro Arg Asn Arg Phe
     130                 135                 140

 gac cac tcc cta gat ttg ctc tgt ccc ccc cac ata gct cca ctt gtg      480
 Asp His Ser Leu Asp Leu Leu Cys Pro Pro His Ile Ala Pro Leu Val
 145                 150                 155                 160

 aaa acc gag ccc cag agg cca gta aag gag gaa gag ccc aag att cca      528
 Lys Thr Glu Pro Gln Arg Pro Val Lys Glu Glu Glu Pro Lys Ile Pro
                 165                 170                 175

 ggg gac ctg gac cag gaa ccg agc ctg ctc tat gcg gat ctg gac cat      576
 Gly Asp Leu Asp Gln Glu Pro Ser Leu Leu Tyr Ala Asp Leu Asp His
             180                 185                 190

 cta gcc ctc agc agg ccc cgc cgg ctg tcc aca gcg gac cct gct gat      624
 Leu Ala Leu Ser Arg Pro Arg Arg Leu Ser Thr Ala Asp Pro Ala Asp
         195                 200                 205

 gcc tcc acc atc tat gca gtt gta gtt tga                              654
 Ala Ser Thr Ile Tyr Ala Val Val Val 
     210                 215





      <210> 785
      <211> 486
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(486)

      <400> 785
  atg aag ctg ctt gcc tat ttt ggt tgt ggt aca ttg atg tgg gct gct      48
  Met Lys Leu Leu Ala Tyr Phe Gly Cys Gly Thr Leu Met Trp Ala Ala
    1               5                  10                  15

 gaa ttt gcg ggc tac att gag aga cct cag ctg att cga gca aaa gtg       96
 Glu Phe Ala Gly Tyr Ile Glu Arg Pro Gln Leu Ile Arg Ala Lys Val
              20                  25                  30

 cca att gtg aag ttc agg gat aaa gtc aga aag cgc tta att gtc cac      144
 Pro Ile Val Lys Phe Arg Asp Lys Val Arg Lys Arg Leu Ile Val His
          35                  40                  45

 att tca gac ttt gaa ggt aac gta aga tat cat ggg aca gtc tca gaa      192
 Ile Ser Asp Phe Glu Gly Asn Val Arg Tyr His Gly Thr Val Ser Glu
      50                  55                  60

 aaa aat gat gga atc tgg caa aag gag tct ttt agt cct gct ata cag      240
 Lys Asn Asp Gly Ile Trp Gln Lys Glu Ser Phe Ser Pro Ala Ile Gln
  65                  70                  75                  80

 ctg cac ctt gta cat caa gct cca tgt aat gtt cct cct tac ctc tca      288
 Leu His Leu Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu Ser
                  85                  90                  95

 aag aat gaa tca aac ctt ggg gac ctc tta ctg ggc ttt ctt aaa tat      336
 Lys Asn Glu Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys Tyr
             100                 105                 110

 tat gct aca gaa ttt gac tgg aat agt caa atg att tca gtt cgt gaa      384
 Tyr Ala Thr Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg Glu
         115                 120                 125

 gcc aaa gcc att cca agg cct gat ggt att gaa tgg aga aat aaa tac      432
 Ala Lys Ala Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys Tyr
     130                 135                 140

 atc tgt gta gaa ggt agt ttt ctg ttt acc atc tac gta tca tca tgg      480
 Ile Cys Val Glu Gly Ser Phe Leu Phe Thr Ile Tyr Val Ser Ser Trp
 145                 150                 155                 160

 tac taa                                                              486
 Tyr 






      <210> 786
      <211> 399
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(399)

      <400> 786
  atg ctg cac aca ctg gag ctt ttg ttt ctg ttg aag atc agt cca ctg      48
  Met Leu His Thr Leu Glu Leu Leu Phe Leu Leu Lys Ile Ser Pro Leu
    1               5                  10                  15

 ctc agt ttc ttc ttc ctg cag ctg gtt gag ttc ttt cca gac aaa gac       96
 Leu Ser Phe Phe Phe Leu Gln Leu Val Glu Phe Phe Pro Asp Lys Asp
              20                  25                  30

 aag ttc ccc aat acg gca aca cct tct ctc ttc tgg cat gtc cag tcc      144
 Lys Phe Pro Asn Thr Ala Thr Pro Ser Leu Phe Trp His Val Gln Ser
          35                  40                  45

 ccc ggc caa ggc ctc cag ctg ctc cta aag tac ttt tca gga gac act      192
 Pro Gly Gln Gly Leu Gln Leu Leu Leu Lys Tyr Phe Ser Gly Asp Thr
      50                  55                  60

 ctg gtt caa ggc att gaa ggc ttt gaa gct gaa ttt aag agg agt caa      240
 Leu Val Gln Gly Ile Glu Gly Phe Glu Ala Glu Phe Lys Arg Ser Gln
  65                  70                  75                  80

 tct tcc ttc aac ctg agg aga ccc tct gtg cat tgg agt gat gct gct      288
 Ser Ser Phe Asn Leu Arg Arg Pro Ser Val His Trp Ser Asp Ala Ala
                  85                  90                  95

 gag tac ttc tgt gct gca ggg aag ctt gaa gta gtt gaa ggt atc gat      336
 Glu Tyr Phe Cys Ala Ala Gly Lys Leu Glu Val Val Glu Gly Ile Asp
             100                 105                 110

 tta ttg act ctc agc tcc aaa ttc act cct tgc ctc ttc tgt gaa ggt      384
 Leu Leu Thr Leu Ser Ser Lys Phe Thr Pro Cys Leu Phe Cys Glu Gly
         115                 120                 125

 cct gaa gat ctg taa                                                  399
 Pro Glu Asp Leu 
     130





      <210> 787
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 787
  atg gcc ctg ctg cag ctc cac gct gtg ggg ggc gtg gcc ctg acc agc      48
  Met Ala Leu Leu Gln Leu His Ala Val Gly Gly Val Ala Leu Thr Ser
    1               5                  10                  15

 agc cac ccc tcc atg tgg gcc aca ggg gag gag ctt agg aag ccg cct       96
 Ser His Pro Ser Met Trp Ala Thr Gly Glu Glu Leu Arg Lys Pro Pro
              20                  25                  30

 tgg caa ggt tcc gca ggc tct gcg tct ggt gtg gaa gag ctc acg ggg      144
 Trp Gln Gly Ser Ala Gly Ser Ala Ser Gly Val Glu Glu Leu Thr Gly
          35                  40                  45

 aag cac tcc tgc cca gga ccc gag gag ccg gcc acc gtt cag aag gcc      192
 Lys His Ser Cys Pro Gly Pro Glu Glu Pro Ala Thr Val Gln Lys Ala
      50                  55                  60

 cca gct tga                                                          201
 Pro Ala 
  65





      <210> 788
      <211> 459
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(459)

      <400> 788
  atg ctt gcc ccc tgc tca ggt tgg gag ctt ggc tgc ttc cgt ctc tgt      48
  Met Leu Ala Pro Cys Ser Gly Trp Glu Leu Gly Cys Phe Arg Leu Cys
    1               5                  10                  15

 ctc cgt cag gtc cga ctg tgg gct ggc gct ggg cgc tgg gct tgc tgg       96
 Leu Arg Gln Val Arg Leu Trp Ala Gly Ala Gly Arg Trp Ala Cys Trp
              20                  25                  30

 gct tgc caa gcc agg ccg tac agc tca ggt ggg agc gag cgc tgg ccc      144
 Ala Cys Gln Ala Arg Pro Tyr Ser Ser Gly Gly Ser Glu Arg Trp Pro
          35                  40                  45

 gga tcg gag act gag gtc cct ccg cct ggc ccg gcg cgc cga act ctg      192
 Gly Ser Glu Thr Glu Val Pro Pro Pro Gly Pro Ala Arg Arg Thr Leu
      50                  55                  60

 aag gag tgg aca ctg cag gtg agc ccg ttt ggt cgg ctg cgg gcg cgg      240
 Lys Glu Trp Thr Leu Gln Val Ser Pro Phe Gly Arg Leu Arg Ala Arg
  65                  70                  75                  80

 ctc ccg tgc cac ctg gcc gtg agg ccc ctg gac ccc ctc acc tac ccg      288
 Leu Pro Cys His Leu Ala Val Arg Pro Leu Asp Pro Leu Thr Tyr Pro
                  85                  90                  95

 gat ggc gac cgc gtg ctg gtc gcg gtg tgc ggc gtg gag ggc ggc gtg      336
 Asp Gly Asp Arg Val Leu Val Ala Val Cys Gly Val Glu Gly Gly Val
             100                 105                 110

 cgg ggc ctg gac ggc ctg cag gtg aag tac gac gag gat ctg gag gag      384
 Arg Gly Leu Asp Gly Leu Gln Val Lys Tyr Asp Glu Asp Leu Glu Glu
         115                 120                 125

 atg gcc att gtg tct gat act atc cac ccc cag gcg tcc gtg gag gtg      432
 Met Ala Ile Val Ser Asp Thr Ile His Pro Gln Ala Ser Val Glu Val
     130                 135                 140

 aac gcg ccc ctg aag ttt ggc aag tga                                  459
 Asn Ala Pro Leu Lys Phe Gly Lys 
 145                 150





      <210> 789
      <211> 1383
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1383)

      <400> 789
  atg agt gag gtc agg atg gtg atg ctc acc tgt gtc tgt ttc tct ttc      48
  Met Ser Glu Val Arg Met Val Met Leu Thr Cys Val Cys Phe Ser Phe
    1               5                  10                  15

 ctt ctg gga cgc atg gga gac tat act tct gag ttg caa aat gtg aac       96
 Leu Leu Gly Arg Met Gly Asp Tyr Thr Ser Glu Leu Gln Asn Val Asn
              20                  25                  30

 aac tgg tgg cag gcg gct caa cga cgc cct ttt aaa ccg ttt gcc ccg      144
 Asn Trp Trp Gln Ala Ala Gln Arg Arg Pro Phe Lys Pro Phe Ala Pro
          35                  40                  45

 gag tgg acc gcc ggg atc gcg tgt cac cac cca acc cta gcg atg att      192
 Glu Trp Thr Ala Gly Ile Ala Cys His His Pro Thr Leu Ala Met Ile
      50                  55                  60

 ggc tat ttc gcc gag gcc gga gga gga acc agc ggc aga acc gga agc      240
 Gly Tyr Phe Ala Glu Ala Gly Gly Gly Thr Ser Gly Arg Thr Gly Ser
  65                  70                  75                  80

 gtc tgc cag ggc atg gag ctc tcc tgc ccc ggt tcg cgg tgc ccg gtg      288
 Val Cys Gln Gly Met Glu Leu Ser Cys Pro Gly Ser Arg Cys Pro Val
                  85                  90                  95

 caa gag cag cgt gcc cgc tgg gag cgg aaa cgc gcc tgc acc gcc cgg      336
 Gln Glu Gln Arg Ala Arg Trp Glu Arg Lys Arg Ala Cys Thr Ala Arg
             100                 105                 110

 gag ctg cta gag acc gag cgg cgc tac caa gaa cag ctg ggg ctg gtg      384
 Glu Leu Leu Glu Thr Glu Arg Arg Tyr Gln Glu Gln Leu Gly Leu Val
         115                 120                 125

 gcc acg tac ttt ttg ggg atc ctg aaa gcc aag ggg acc ctg cga cca      432
 Ala Thr Tyr Phe Leu Gly Ile Leu Lys Ala Lys Gly Thr Leu Arg Pro
     130                 135                 140

 cct gag cgc cag gcc ctg ttt ggc tcc tgg gag ctc atc tac ggc gcc      480
 Pro Glu Arg Gln Ala Leu Phe Gly Ser Trp Glu Leu Ile Tyr Gly Ala
 145                 150                 155                 160

 agc cag gag ctg ctt ccc tac ctg gaa gga gga tgc tgg ggc caa ggg      528
 Ser Gln Glu Leu Leu Pro Tyr Leu Glu Gly Gly Cys Trp Gly Gln Gly
                 165                 170                 175

 ctg gag ggc ttc tgc cgc cac ttg gag ctc tat aac caa ttt gct gcc      576
 Leu Glu Gly Phe Cys Arg His Leu Glu Leu Tyr Asn Gln Phe Ala Ala
             180                 185                 190

 aac tca gag agg tcc cag acc acc ctg cag gag cag cta aag aaa aat      624
 Asn Ser Glu Arg Ser Gln Thr Thr Leu Gln Glu Gln Leu Lys Lys Asn
         195                 200                 205

 aaa ggt ttc cgg agg ttt gta cgg ctt cag gaa ggc cgc cct gag ttt      672
 Lys Gly Phe Arg Arg Phe Val Arg Leu Gln Glu Gly Arg Pro Glu Phe
     210                 215                 220

 ggg ggc ctt cag ctc cag gac ctg ctc cct ctg cct ctg caa cgg ctc      720
 Gly Gly Leu Gln Leu Gln Asp Leu Leu Pro Leu Pro Leu Gln Arg Leu
 225                 230                 235                 240

 cag cag tat gag aat ctc gtc gta gct ttg gct gaa aac aca ggt ccc      768
 Gln Gln Tyr Glu Asn Leu Val Val Ala Leu Ala Glu Asn Thr Gly Pro
                 245                 250                 255

 aac agc cct gac cat caa cag ctc aca ctg tcc cta ctg ctc tgc ctt      816
 Asn Ser Pro Asp His Gln Gln Leu Thr Leu Ser Leu Leu Leu Cys Leu
             260                 265                 270

 ttc ttc aag aag tca gac cct gac cct ggt ccc ttc cag aat aac ctc      864
 Phe Phe Lys Lys Ser Asp Pro Asp Pro Gly Pro Phe Gln Asn Asn Leu
         275                 280                 285

 ttt cac aac cat ggc acc caa agt caa agt tgt atg ggg agt aag gtg      912
 Phe His Asn His Gly Thr Gln Ser Gln Ser Cys Met Gly Ser Lys Val
     290                 295                 300

 gga gat gtt att cca ggg gct gcc cga ctg ata agt gag act gcc cag      960
 Gly Asp Val Ile Pro Gly Ala Ala Arg Leu Ile Ser Glu Thr Ala Gln
 305                 310                 315                 320

 aga gtc cat act att ggt cag aaa cag aag aat gac cag cac ctt cgg     1008
 Arg Val His Thr Ile Gly Gln Lys Gln Lys Asn Asp Gln His Leu Arg
                 325                 330                 335

 cgt gtc cag gct ctg ctc agt gga cgc cag gca aag ggg ctg acc tca     1056
 Arg Val Gln Ala Leu Leu Ser Gly Arg Gln Ala Lys Gly Leu Thr Ser
             340                 345                 350

 ggg cgc tgg ttc cta cgc cag ggc tgg ctg tta gtg gtg cct ccc cat     1104
 Gly Arg Trp Phe Leu Arg Gln Gly Trp Leu Leu Val Val Pro Pro His
         355                 360                 365

 ggg gag cct cgg ccc cgc atg ttc ttc ctc ttc act gat gtg ctc ctc     1152
 Gly Glu Pro Arg Pro Arg Met Phe Phe Leu Phe Thr Asp Val Leu Leu
     370                 375                 380

 atg gcc aag cct cgg cct cca ctg cac ctg ctg cgg agt ggc acc ttt     1200
 Met Ala Lys Pro Arg Pro Pro Leu His Leu Leu Arg Ser Gly Thr Phe
 385                 390                 395                 400

 gcc tgc aag gcc ctc tac ccc atg gcc cag tgt cat ctc agc agg gtc     1248
 Ala Cys Lys Ala Leu Tyr Pro Met Ala Gln Cys His Leu Ser Arg Val
                 405                 410                 415

 ttt ggc cac tca gga ggc cct tgt ggt ggg ttg ctc agt cag cca gaa     1296
 Phe Gly His Ser Gly Gly Pro Cys Gly Gly Leu Leu Ser Gln Pro Glu
             420                 425                 430

 aaa cta gag gaa tct tat aga ttc cag aac tca gga tac ctc agg gat     1344
 Lys Leu Glu Glu Ser Tyr Arg Phe Gln Asn Ser Gly Tyr Leu Arg Asp
         435                 440                 445

 agg tca cag cca aga gta caa agg aat ctt cag tac tga                 1383
 Arg Ser Gln Pro Arg Val Gln Arg Asn Leu Gln Tyr 
     450                 455                 460





      <210> 790
      <211> 921
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(921)

      <400> 790
  atg ttg ttg tca ctg ctg ggt gcc tgt gct gtg gtg ggg cca ttc cat      48
  Met Leu Leu Ser Leu Leu Gly Ala Cys Ala Val Val Gly Pro Phe His
    1               5                  10                  15

 ggc cct gag tgg gag cca gtg cag ggc ctg ctc tcc cag aat cac agc       96
 Gly Pro Glu Trp Glu Pro Val Gln Gly Leu Leu Ser Gln Asn His Ser
              20                  25                  30

 tgc agg gac cct cag tgc tgt ggc aac ctg ctt gtc ctc tgc ctc ttt      144
 Cys Arg Asp Pro Gln Cys Cys Gly Asn Leu Leu Val Leu Cys Leu Phe
          35                  40                  45

 ctg gtc tgg cag gtc cgg cac tgt tgg cac cag gtc acc agg acc cgc      192
 Leu Val Trp Gln Val Arg His Cys Trp His Gln Val Thr Arg Thr Arg
      50                  55                  60

 ttc agc aca agg aat gtc atc aag gca cat atg gga gag aac caa gaa      240
 Phe Ser Thr Arg Asn Val Ile Lys Ala His Met Gly Glu Asn Gln Glu
  65                  70                  75                  80

 cag tta aga tgt aaa att gat gca gag acc caa aca cct gag tgg gag      288
 Gln Leu Arg Cys Lys Ile Asp Ala Glu Thr Gln Thr Pro Glu Trp Glu
                  85                  90                  95

 aac cag gat aag aat gga agt gag gat gct gtg gag acc cag aca ttt      336
 Asn Gln Asp Lys Asn Gly Ser Glu Asp Ala Val Glu Thr Gln Thr Phe
             100                 105                 110

 gag aag aag gac aag aaa gag gct gga gag gag gat ggg gaa gag atc      384
 Glu Lys Lys Asp Lys Lys Glu Ala Gly Glu Glu Asp Gly Glu Glu Ile
         115                 120                 125

 cag gct caa gga ttg ggg aag caa ggc cag act gga gat gag aat ggt      432
 Gln Ala Gln Gly Leu Gly Lys Gln Gly Gln Thr Gly Asp Glu Asn Gly
     130                 135                 140

 gag gag acc cag aca cca cag tgg gag aaa caa gat cag atg aaa ggt      480
 Glu Glu Thr Gln Thr Pro Gln Trp Glu Lys Gln Asp Gln Met Lys Gly
 145                 150                 155                 160

 gat gcg gat gtg gaa att cag atg gaa gag ggg aga aac aag gat cag      528
 Asp Ala Asp Val Glu Ile Gln Met Glu Glu Gly Arg Asn Lys Asp Gln
                 165                 170                 175

 gtt gga ggt cag gat gct gca caa acc caa tca tgt ggg agg gag aac      576
 Val Gly Gly Gln Asp Ala Ala Gln Thr Gln Ser Cys Gly Arg Glu Asn
             180                 185                 190

 gtg gga gaa gta aaa aaa gag aat agt gta gag acc cag gcc ttg gat      624
 Val Gly Glu Val Lys Lys Glu Asn Ser Val Glu Thr Gln Ala Leu Asp
         195                 200                 205

 tgg gga aaa cag gaa tgt gtt gga aat ggg aat gtt aca gag atc cag      672
 Trp Gly Lys Gln Glu Cys Val Gly Asn Gly Asn Val Thr Glu Ile Gln
     210                 215                 220

 aca cca agg tgg gag aag cat gat caa ggt gga agt aag aaa gct aag      720
 Thr Pro Arg Trp Glu Lys His Asp Gln Gly Gly Ser Lys Lys Ala Lys
 225                 230                 235                 240

 aag acc caa gca tct ggg gga gag aac cag aaa caa tta agt cat gaa      768
 Lys Thr Gln Ala Ser Gly Gly Glu Asn Gln Lys Gln Leu Ser His Glu
                 245                 250                 255

 att caa gtg ggg tgg gga aat aag ggc ctg aga aga gat gaa gat gct      816
 Ile Gln Val Gly Trp Gly Asn Lys Gly Leu Arg Arg Asp Glu Asp Ala
             260                 265                 270

 aag gaa acc cag ata gct acc aag aag aag ctc agg gag ata aga gaa      864
 Lys Glu Thr Gln Ile Ala Thr Lys Lys Lys Leu Arg Glu Ile Arg Glu
         275                 280                 285

 gga ttg ggt ggt gat cca ggc act atg gtg ggg aaa ccg gag aca agt      912
 Gly Leu Gly Gly Asp Pro Gly Thr Met Val Gly Lys Pro Glu Thr Ser
     290                 295                 300

 agc aag tga                                                          921
 Ser Lys 
 305





      <210> 791
      <211> 1338
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1338)

      <400> 791
  atg gtt gtc ctc gtc tgg cca ttc ctg atg ctg tgt gtg cct ttc tgt      48
  Met Val Val Leu Val Trp Pro Phe Leu Met Leu Cys Val Pro Phe Cys
    1               5                  10                  15

 ttg cac gct tgt ttg aca tcc ctt tgt atc ttc agg gcc tgg gac aaa       96
 Leu His Ala Cys Leu Thr Ser Leu Cys Ile Phe Arg Ala Trp Asp Lys
              20                  25                  30

 tgc ctt gca ttt agt aag cgt cca ata aat att cat aca gat atg gat      144
 Cys Leu Ala Phe Ser Lys Arg Pro Ile Asn Ile His Thr Asp Met Asp
          35                  40                  45

 ttt caa aag ctc ctc atc tgg aaa tcc gag gac agt aat gct tat ctc      192
 Phe Gln Lys Leu Leu Ile Trp Lys Ser Glu Asp Ser Asn Ala Tyr Leu
      50                  55                  60

 aaa acc att gtg aaa att aaa aga gat gaa gta ggc gaa gag cca tct      240
 Lys Thr Ile Val Lys Ile Lys Arg Asp Glu Val Gly Glu Glu Pro Ser
  65                  70                  75                  80

 tgg cag cat ggg atg ctc tgc gtc tta ttg cag tgg cct tgt tgt tgg      288
 Trp Gln His Gly Met Leu Cys Val Leu Leu Gln Trp Pro Cys Cys Trp
                  85                  90                  95

 aaa gtg gtt gct gag tcc tct gca gac cag cac ctc cca tca ggc aaa      336
 Lys Val Val Ala Glu Ser Ser Ala Asp Gln His Leu Pro Ser Gly Lys
             100                 105                 110

 ctc aga cca gca cct gcc atc agg caa act cag acc agc acc tgc cat      384
 Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His
         115                 120                 125

 cag gta aac tca gac cag cac ctg cca tca ggc aaa ctc aga cca gca      432
 Gln Val Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
     130                 135                 140

 cct gcc atc agg caa act cag acc agc acc tgc cat cag gca aac tca      480
 Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser
 145                 150                 155                 160

 gac cag cac ctc cca tca ggc aaa ctc aga cca gct cct ccc atc agg      528
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Pro Ile Arg
                 165                 170                 175

 caa act cag acc agc acc tgc cat cag gca aac tca gac cag cac ctc      576
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
             180                 185                 190

 cca tca ggc aaa ctc aga cca gca cct gcc atc agg caa act cag acc      624
 Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Thr
         195                 200                 205

 agc acc tcc cat cag gca aac tca gac cag cac ctg cca tca ggc aaa      672
 Ser Thr Ser His Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys
     210                 215                 220

 ctc aga cca gca cct ccc atc agg caa act cag acc agc acc tgc cat      720
 Leu Arg Pro Ala Pro Pro Ile Arg Gln Thr Gln Thr Ser Thr Cys His
 225                 230                 235                 240

 cag gca aac tca gac cag cac ctc cca tca ggc aaa ctc aga cca gca      768
 Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
                 245                 250                 255

 cct gcc atc agg caa act cag acc agc acc tgc cat cag gca aac tca      816
 Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser
             260                 265                 270

 gac cag cac ctc cca tca ggc aaa ctc aga cca gct cct ccc atc agg      864
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Pro Ile Arg
         275                 280                 285

 caa act cag acc agc acc tgc cat cag gca aac tca gac cag cac ctc      912
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
     290                 295                 300

 cca tca ggc aaa ctc aga cca gca cct gcc atc agg caa act cag agc      960
 Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Ser
 305                 310                 315                 320

 agc acc tcc cat cag gca aac tca gac cag cac ctg cca tca ggc aaa     1008
 Ser Thr Ser His Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys
                 325                 330                 335

 ctc aga cca gca cct ccc atc agg caa act cag acc agc acc tgc cat     1056
 Leu Arg Pro Ala Pro Pro Ile Arg Gln Thr Gln Thr Ser Thr Cys His
             340                 345                 350

 cag gca aac tca gac cag cac ctc cca tca ggc aaa ctc aga cca gca     1104
 Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
         355                 360                 365

 cct gcc atc tgg cta act cag acc agc acc tcc cat cag gca aac tca     1152
 Pro Ala Ile Trp Leu Thr Gln Thr Ser Thr Ser His Gln Ala Asn Ser
     370                 375                 380

 gac cag cac ctg cca tca ggc aaa ctc aga cca gca cct gcc atc agg     1200
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg
 385                 390                 395                 400

 caa act cag acc agc acc tgc cat cag gca aac tca gac cag cac ctg     1248
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
                 405                 410                 415

 cca tca ggc aaa ctt atc cag cag ctg aca gtc aca gga act agg gga     1296
 Pro Ser Gly Lys Leu Ile Gln Gln Leu Thr Val Thr Gly Thr Arg Gly
             420                 425                 430

 aca aca cct gct ttg gtg cag aga aga gca gga gaa gag taa             1338
 Thr Thr Pro Ala Leu Val Gln Arg Arg Ala Gly Glu Glu 
         435                 440                 445





      <210> 792
      <211> 951
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(951)

      <400> 792
  atg tct ggc ctg gct tta aga gcc atg tac tcc ttc ttg ctg gac ttc      48
  Met Ser Gly Leu Ala Leu Arg Ala Met Tyr Ser Phe Leu Leu Asp Phe
    1               5                  10                  15

 atg gag gcc cac agt aag cgc tgg aag aaa acc agg agt ggg aac cag       96
 Met Glu Ala His Ser Lys Arg Trp Lys Lys Thr Arg Ser Gly Asn Gln
              20                  25                  30

 gaa tgg gtg cca gag ggc aag cct gag ctg cag gtg ctc agg ccc agt      144
 Glu Trp Val Pro Glu Gly Lys Pro Glu Leu Gln Val Leu Arg Pro Ser
          35                  40                  45

 ccc aag gcg caa gaa cac ttg cgc cag cag cgt gca tca gca aga cag      192
 Pro Lys Ala Gln Glu His Leu Arg Gln Gln Arg Ala Ser Ala Arg Gln
      50                  55                  60

 cag aag cag gaa gag aga cgg ccg gca gaa gac acg tac ccc ctg aag      240
 Gln Lys Gln Glu Glu Arg Arg Pro Ala Glu Asp Thr Tyr Pro Leu Lys
  65                  70                  75                  80

 gct gag aga gag gcc gtc cgg cct tca aag tcc tta aca atc gtg atg      288
 Ala Glu Arg Glu Ala Val Arg Pro Ser Lys Ser Leu Thr Ile Val Met
                  85                  90                  95

 aga aaa gta aaa gtc aaa aaa cag gca gag ttt caa atg ctt gca tct      336
 Arg Lys Val Lys Val Lys Lys Gln Ala Glu Phe Gln Met Leu Ala Ser
             100                 105                 110

 gcc atc agg ggc tct gtg ggc cca cgg ggc agc agc tcc aca cag aag      384
 Ala Ile Arg Gly Ser Val Gly Pro Arg Gly Ser Ser Ser Thr Gln Lys
         115                 120                 125

 cct cct agc aat cca cct cca ctt ggt gcc tgt ttc aag tgt ggc aat      432
 Pro Pro Ser Asn Pro Pro Pro Leu Gly Ala Cys Phe Lys Cys Gly Asn
     130                 135                 140

 gaa ggc cac tgg tcc aga caa tgc cca aac cca gac cta cag gat gct      480
 Glu Gly His Trp Ser Arg Gln Cys Pro Asn Pro Asp Leu Gln Asp Ala
 145                 150                 155                 160

 gtt ttc aca att cct tta cac cct gat tcc caa aac ctc ttt gtc ttt      528
 Val Phe Thr Ile Pro Leu His Pro Asp Ser Gln Asn Leu Phe Val Phe
                 165                 170                 175

 aca tgg gaa aac ccc gac acc cac ctt tca cat cag ctt acc tgg tgc      576
 Thr Trp Glu Asn Pro Asp Thr His Leu Ser His Gln Leu Thr Trp Cys
             180                 185                 190

 ata cta act caa ggt ttc aga gac agc ccc cac ctt ttt ggg cag gcc      624
 Ile Leu Thr Gln Gly Phe Arg Asp Ser Pro His Leu Phe Gly Gln Ala
         195                 200                 205

 ctg gct cgt gac ctc tgt acc tta tcc cta aaa cca tcc act ctc ctt      672
 Leu Ala Arg Asp Leu Cys Thr Leu Ser Leu Lys Pro Ser Thr Leu Leu
     210                 215                 220

 cag tat gtt gat gat cta cac cta tgt aga ccc tct caa aga gac tgc      720
 Gln Tyr Val Asp Asp Leu His Leu Cys Arg Pro Ser Gln Arg Asp Cys
 225                 230                 235                 240

 aat gtc cat acc atc tct ctt tta aac ttc ttg gca gaa tgg ggg cat      768
 Asn Val His Thr Ile Ser Leu Leu Asn Phe Leu Ala Glu Trp Gly His
                 245                 250                 255

 cag gtc tcc cct aag aaa gca caa ata agc acc ccc cca gtc acc tat      816
 Gln Val Ser Pro Lys Lys Ala Gln Ile Ser Thr Pro Pro Val Thr Tyr
             260                 265                 270

 cta ggc cta gct ctt acc ccg caa acc cga ggg ctc aca acc gat ggc      864
 Leu Gly Leu Ala Leu Thr Pro Gln Thr Arg Gly Leu Thr Thr Asp Gly
         275                 280                 285

 ata tcc ctc ctc cag tcc ctc cca cct cca caa act aag caa gaa att      912
 Ile Ser Leu Leu Gln Ser Leu Pro Pro Pro Gln Thr Lys Gln Glu Ile
     290                 295                 300

 atc tct ttt cta gga cta gca gga tat ttt agg ctc tga                  951
 Ile Ser Phe Leu Gly Leu Ala Gly Tyr Phe Arg Leu 
 305                 310                 315





      <210> 793
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 793
  atg gcc ttc aac ctg ggg ccc gtt ggc cag agc tcg gcc tct cag aga      48
  Met Ala Phe Asn Leu Gly Pro Val Gly Gln Ser Ser Ala Ser Gln Arg
    1               5                  10                  15

 ccg ctg cag gcc ctg cct cac ctc atg ttc ctc ctg gcc ctg cac ctc       96
 Pro Leu Gln Ala Leu Pro His Leu Met Phe Leu Leu Ala Leu His Leu
              20                  25                  30

 cag cca tcc act gcg gct ctc acg gct cag tac ggt cgg aat ttg cgc      144
 Gln Pro Ser Thr Ala Ala Leu Thr Ala Gln Tyr Gly Arg Asn Leu Arg
          35                  40                  45

 tgg gcc cgc agc agc tcg atc ctc tgc ttg tcc tcc tca aac ttc ttg      192
 Trp Ala Arg Ser Ser Ser Ile Leu Cys Leu Ser Ser Ser Asn Phe Leu
      50                  55                  60

 cgc agc tgc gct aga tct ggg ggg tct gga tct tgt cag gaa aca gaa      240
 Arg Ser Cys Ala Arg Ser Gly Gly Ser Gly Ser Cys Gln Glu Thr Glu
  65                  70                  75                  80

 ccg acg gca ggc cag gcc gag tcc aag ggc aag gcc aaa gtg gga gat      288
 Pro Thr Ala Gly Gln Ala Glu Ser Lys Gly Lys Ala Lys Val Gly Asp
                  85                  90                  95

 gct ggc acc ccc agc ctg gag atg aag ccc tag                          321
 Ala Gly Thr Pro Ser Leu Glu Met Lys Pro 
             100                 105





      <210> 794
      <211> 279
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(279)

      <400> 794
  atg gcg ggg ctc cga cgc ccg cag ccc ggc tgc tac tgc cgc acc gcg      48
  Met Ala Gly Leu Arg Arg Pro Gln Pro Gly Cys Tyr Cys Arg Thr Ala
    1               5                  10                  15

 gcg gcc gtg aac ctc ctg ctg ggc gtc ttc cag gaa ttg tgt atg gca       96
 Ala Ala Val Asn Leu Leu Leu Gly Val Phe Gln Glu Leu Cys Met Ala
              20                  25                  30

 gag gct aaa ctg ctg atg ggg aga ccc cca aat aca gct gct cag ttc      144
 Glu Ala Lys Leu Leu Met Gly Arg Pro Pro Asn Thr Ala Ala Gln Phe
          35                  40                  45

 atg gtg ctc tca ttt aat agt ccg ggg ctg gtg gtt gac tcc tcc atg      192
 Met Val Leu Ser Phe Asn Ser Pro Gly Leu Val Val Asp Ser Ser Met
      50                  55                  60

 agg ttg ttc act ggg gtc ttc cta ttt cat agc tgt acc atc ttg cgg      240
 Arg Leu Phe Thr Gly Val Phe Leu Phe His Ser Cys Thr Ile Leu Arg
  65                  70                  75                  80

 gat gtt agc ctt gcc att gtg gtg gga cct gcc tta taa                  279
 Asp Val Ser Leu Ala Ile Val Val Gly Pro Ala Leu 
                  85                  90





      <210> 795
      <211> 303
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(303)

      <400> 795
  atg ttg tgg cca gat ccc ctt tcc tgg tgt ttt ctg ggt aga tgt cca      48
  Met Leu Trp Pro Asp Pro Leu Ser Trp Cys Phe Leu Gly Arg Cys Pro
    1               5                  10                  15

 gtg tct ctg aat gtt cag tgc ctc tgg gta gac gag agt cgc agt ccc       96
 Val Ser Leu Asn Val Gln Cys Leu Trp Val Asp Glu Ser Arg Ser Pro
              20                  25                  30

 aca gaa aca aag agg ctt tct ggg cca ctt cta gaa tcc ttc ttg ttg      144
 Thr Glu Thr Lys Arg Leu Ser Gly Pro Leu Leu Glu Ser Phe Leu Leu
          35                  40                  45

 gag cca ctc aga tac ctg atg tct ctt ggt ggg aaa gag aag ctg cag      192
 Glu Pro Leu Arg Tyr Leu Met Ser Leu Gly Gly Lys Glu Lys Leu Gln
      50                  55                  60

 gtc cgc atg ctg cct gga gca cag tta gta ctc aaa tat ata gag tat      240
 Val Arg Met Leu Pro Gly Ala Gln Leu Val Leu Lys Tyr Ile Glu Tyr
  65                  70                  75                  80

 aat tta gaa att cct cat gtc agt atg caa gag caa tac tct att aat      288
 Asn Leu Glu Ile Pro His Val Ser Met Gln Glu Gln Tyr Ser Ile Asn
                  85                  90                  95

 caa ctt gct tgg tag                                                  303
 Gln Leu Ala Trp 
             100





      <210> 796
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 796
  atg act cta aca ctg ggt cta tct gga gtc atg aca ctg cag ccc ttt      48
  Met Thr Leu Thr Leu Gly Leu Ser Gly Val Met Thr Leu Gln Pro Phe
    1               5                  10                  15

 gtt tgg gca tgg tgg ggt gaa aag ggg atc cag gga tgt gaa gat gca       96
 Val Trp Ala Trp Trp Gly Glu Lys Gly Ile Gln Gly Cys Glu Asp Ala
              20                  25                  30

 ggg gct att ggg ttc cag ggc agg atg cgc ttt agc agt agc tct gtt      144
 Gly Ala Ile Gly Phe Gln Gly Arg Met Arg Phe Ser Ser Ser Ser Val
          35                  40                  45

 tgc aaa gtg gtg aca ggc tgc agc agc ttg ggt cct ggg gat ttg ggg      192
 Cys Lys Val Val Thr Gly Cys Ser Ser Leu Gly Pro Gly Asp Leu Gly
      50                  55                  60

 aga tcc agc atg aat ttc ctc tct gga gca atg cag cta tat gga ctc      240
 Arg Ser Ser Met Asn Phe Leu Ser Gly Ala Met Gln Leu Tyr Gly Leu
  65                  70                  75                  80

 caa gca gct cgc tat att ggg ctt agg gtc tgt gag gac tgt ggg act      288
 Gln Ala Ala Arg Tyr Ile Gly Leu Arg Val Cys Glu Asp Cys Gly Thr
                  85                  90                  95

 ctt ata tag                                                          297
 Leu Ile 






      <210> 797
      <211> 390
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(390)

      <400> 797
  atg act cca aag cac gac cat ctg ggg cac gtg ctg ccg atc tct ctg      48
  Met Thr Pro Lys His Asp His Leu Gly His Val Leu Pro Ile Ser Leu
    1               5                  10                  15

 cag ctg ctg ttg gaa ttg tct tcc tgt ctt cct gca gcc tcc gcc gtg       96
 Gln Leu Leu Leu Glu Leu Ser Ser Cys Leu Pro Ala Ala Ser Ala Val
              20                  25                  30

 tgg tgt gcc ggc tgt aat gac cca tgg gtg aca ggt tac ccg gac aac      144
 Trp Cys Ala Gly Cys Asn Asp Pro Trp Val Thr Gly Tyr Pro Asp Asn
          35                  40                  45

 atg cat tac aat tac aag cca atg ctg cat gac aga gga ggc tcg gca      192
 Met His Tyr Asn Tyr Lys Pro Met Leu His Asp Arg Gly Gly Ser Ala
      50                  55                  60

 gtg acg ttg tct gcc tcg cag agt tgg tat gct ggc tgt aat gct gaa      240
 Val Thr Leu Ser Ala Ser Gln Ser Trp Tyr Ala Gly Cys Asn Ala Glu
  65                  70                  75                  80

 aag tca gaa gta aac gcg ttc ccc ggg acc cag ggc atg cgc ttc atc      288
 Lys Ser Glu Val Asn Ala Phe Pro Gly Thr Gln Gly Met Arg Phe Ile
                  85                  90                  95

 tca gcg gct tct tac aag gat tgg gtg caa gtg ctg cag cag aaa gat      336
 Ser Ala Ala Ser Tyr Lys Asp Trp Val Gln Val Leu Gln Gln Lys Asp
             100                 105                 110

 gtt tcc agg aac atg gga acc aag gct agg tct gca tct tct ctg aaa      384
 Val Ser Arg Asn Met Gly Thr Lys Ala Arg Ser Ala Ser Ser Leu Lys
         115                 120                 125

 aac tag                                                              390
 Asn 






      <210> 798
      <211> 288
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(288)

      <400> 798
  atg ctg ccc ggt ttg gca ctg ctc ctg ctg gcc gcc tgg acg gct cgg      48
  Met Leu Pro Gly Leu Ala Leu Leu Leu Leu Ala Ala Trp Thr Ala Arg
    1               5                  10                  15

 gcg ctg gag agc tta gaa aat agg tct gct gca ggt ggc tgt aga aaa       96
 Ala Leu Glu Ser Leu Glu Asn Arg Ser Ala Ala Gly Gly Cys Arg Lys
              20                  25                  30

 gaa atg aat aag ggc aat gat aat ggg gcc ttg gct atc ggg gga aac      144
 Glu Met Asn Lys Gly Asn Asp Asn Gly Ala Leu Ala Ile Gly Gly Asn
          35                  40                  45

 atg gtt att atc tgg gtt gat gat ttt ggc tgg tat gtt gat aga gga      192
 Met Val Ile Ile Trp Val Asp Asp Phe Gly Trp Tyr Val Asp Arg Gly
      50                  55                  60

 ctt ctc atc tgt ggc aag gct tta ctc aca aag gaa ata tca acc ttg      240
 Leu Leu Ile Cys Gly Lys Ala Leu Leu Thr Lys Glu Ile Ser Thr Leu
  65                  70                  75                  80

 aag tta agc atg ccc tgt gtt tct tta tat tct gat gaa aac gat tga      288
 Lys Leu Ser Met Pro Cys Val Ser Leu Tyr Ser Asp Glu Asn Asp 
                  85                  90                  95





      <210> 799
      <211> 681
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(681)

      <400> 799
  atg acc ttt aag gtg ctt tcc agc acc tgg ggt ttt atg att cta ttt      48
  Met Thr Phe Lys Val Leu Ser Ser Thr Trp Gly Phe Met Ile Leu Phe
    1               5                  10                  15

 cta tta tgc atc tac gct ggg att gaa gag tca cat tca ctg aat att       96
 Leu Leu Cys Ile Tyr Ala Gly Ile Glu Glu Ser His Ser Leu Asn Ile
              20                  25                  30

 cac atc atg caa gcc att tct gct atg agc cag agg cag tat gtc aca      144
 His Ile Met Gln Ala Ile Ser Ala Met Ser Gln Arg Gln Tyr Val Thr
          35                  40                  45

 tta acc ttc att aac tgc cca aga aat gag ctc cac ggc tgc atc tcc      192
 Leu Thr Phe Ile Asn Cys Pro Arg Asn Glu Leu His Gly Cys Ile Ser
      50                  55                  60

 gtg ggc acg caa gct tcc cct ggt tac ctg agc tgc tcc tgc cgt ctc      240
 Val Gly Thr Gln Ala Ser Pro Gly Tyr Leu Ser Cys Ser Cys Arg Leu
  65                  70                  75                  80

 ccg cct ggg ctt cgc cgt ggt gca ccc gat ccc gga atc gtg cgt ctg      288
 Pro Pro Gly Leu Arg Arg Gly Ala Pro Asp Pro Gly Ile Val Arg Leu
                  85                  90                  95

 cgc cct gcg aaa gaa gga cct gct ggc gga gct ccg gcc ggg gtc tcc      336
 Arg Pro Ala Lys Glu Gly Pro Ala Gly Gly Ala Pro Ala Gly Val Ser
             100                 105                 110

 tgc ctc gca gct ggg cga ggg gac ttg gag gac agg ggc aag ggc agc      384
 Cys Leu Ala Ala Gly Arg Gly Asp Leu Glu Asp Arg Gly Lys Gly Ser
         115                 120                 125

 cgt cgc ctc ggc cgc gtg cac cca gct cag gct gtt ccc agg gat tta      432
 Arg Arg Leu Gly Arg Val His Pro Ala Gln Ala Val Pro Arg Asp Leu
     130                 135                 140

 gtc tgg ggg gac aac cca tgg cga gat gtg gtg gca ttt tac ctc aga      480
 Val Trp Gly Asp Asn Pro Trp Arg Asp Val Val Ala Phe Tyr Leu Arg
 145                 150                 155                 160

 gtg gag ctg aag atg gat aaa caa ggt ggc tta ccc atg att cac ata      528
 Val Glu Leu Lys Met Asp Lys Gln Gly Gly Leu Pro Met Ile His Ile
                 165                 170                 175

 tac atg aaa cag att caa agc ctc cag tta aag ata aaa tat ctg aat      576
 Tyr Met Lys Gln Ile Gln Ser Leu Gln Leu Lys Ile Lys Tyr Leu Asn
             180                 185                 190

 tgg gac cag agt tgt cat cca gaa atc aga att tgc agt tct gag gtg      624
 Trp Asp Gln Ser Cys His Pro Glu Ile Arg Ile Cys Ser Ser Glu Val
         195                 200                 205

 aaa caa gat aat ttt gtg gta aat tta aag gga aga aca ctc ata gga      672
 Lys Gln Asp Asn Phe Val Val Asn Leu Lys Gly Arg Thr Leu Ile Gly
     210                 215                 220

 gaa aac taa                                                          681
 Glu Asn 
 225





      <210> 800
      <211> 516
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(516)

      <400> 800
  atg aaa gtg acc tcc ctt ggc ctc tgt tct ttc tac tgt gca gtc ccc      48
  Met Lys Val Thr Ser Leu Gly Leu Cys Ser Phe Tyr Cys Ala Val Pro
    1               5                  10                  15

 aca gag acc acc tat cac acg ctg gag gag ggc gtg gtg gag tac tgc       96
 Thr Glu Thr Thr Tyr His Thr Leu Glu Glu Gly Val Val Glu Tyr Cys
              20                  25                  30

 acg gct gag gcg ccc cca cct ctg cca cca gag acc cct gtg gac atg      144
 Thr Ala Glu Ala Pro Pro Pro Leu Pro Pro Glu Thr Pro Val Asp Met
          35                  40                  45

 atg gcc cag cat gca gac acg tcg gtc aag ccg caa gcg ctc aag agc      192
 Met Ala Gln His Ala Asp Thr Ser Val Lys Pro Gln Ala Leu Lys Ser
      50                  55                  60

 cgc att gct ctc aac tcc gcc aag ctg ata cag gag cag cgg gtc acc      240
 Arg Ile Ala Leu Asn Ser Ala Lys Leu Ile Gln Glu Gln Arg Val Thr
  65                  70                  75                  80

 aac ctg cat gtg aag gag atc gca cag cac ctg gaa cag cag aac gac      288
 Asn Leu His Val Lys Glu Ile Ala Gln His Leu Glu Gln Gln Asn Asp
                  85                  90                  95

 cta ctg cag atg atc cgc cgc tcc cag gaa gtg cag gcc tgt gcc cag      336
 Leu Leu Gln Met Ile Arg Arg Ser Gln Glu Val Gln Ala Cys Ala Gln
             100                 105                 110

 gag cgc cag gcc cag gcc atg gag ggc aca cag gct gcc ctg agc gtc      384
 Glu Arg Gln Ala Gln Ala Met Glu Gly Thr Gln Ala Ala Leu Ser Val
         115                 120                 125

 ctc atc cag gtc ctc cgg cct atg atc aaa gat ttc cgc cgc tac ctg      432
 Leu Ile Gln Val Leu Arg Pro Met Ile Lys Asp Phe Arg Arg Tyr Leu
     130                 135                 140

 cag agc aac aca gct aac ccg gcc ccc gcc tct gac cct ggg cag gtg      480
 Gln Ser Asn Thr Ala Asn Pro Ala Pro Ala Ser Asp Pro Gly Gln Val
 145                 150                 155                 160

 gcc cag aat ggg cag cca gac agc atc atc cag tga                      516
 Ala Gln Asn Gly Gln Pro Asp Ser Ile Ile Gln 
                 165                 170





      <210> 801
      <211> 834
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(834)

      <400> 801
  atg gcc ctg ccc atg ggg tgc ctt tgg gag tgg att gaa gcc ctg ggc      48
  Met Ala Leu Pro Met Gly Cys Leu Trp Glu Trp Ile Glu Ala Leu Gly
    1               5                  10                  15

 ctg gcc att tgg agt gtc agg gtt ggc agt cac cct gat gga ggg tgg       96
 Leu Ala Ile Trp Ser Val Arg Val Gly Ser His Pro Asp Gly Gly Trp
              20                  25                  30

 gcc tca gga tgt ggc cct ggg cag cct ggc aga gaa cct ctt ccc agg      144
 Ala Ser Gly Cys Gly Pro Gly Gln Pro Gly Arg Glu Pro Leu Pro Arg
          35                  40                  45

 cag aga agc ctc ttc cca agg cgc aag aaa ccg aca cca tca gtt ggg      192
 Gln Arg Ser Leu Phe Pro Arg Arg Lys Lys Pro Thr Pro Ser Val Gly
      50                  55                  60

 ggt gag tgc agt ggc cac act gct ggc tgg atc cct gaa gtg ggc acc      240
 Gly Glu Cys Ser Gly His Thr Ala Gly Trp Ile Pro Glu Val Gly Thr
  65                  70                  75                  80

 agt cac tgc tcc cat ttc tca ccc cgg gct cag ccc cca tgc tcc agc      288
 Ser His Cys Ser His Phe Ser Pro Arg Ala Gln Pro Pro Cys Ser Ser
                  85                  90                  95

 cgc tcc aga cgg tct gct gct gcc atc agt act atc aaa gtg att tcc      336
 Arg Ser Arg Arg Ser Ala Ala Ala Ile Ser Thr Ile Lys Val Ile Ser
             100                 105                 110

 ccg gaa tca ttc cct gga aaa atc agt aca aac gtg gca ctg ccc tgg      384
 Pro Glu Ser Phe Pro Gly Lys Ile Ser Thr Asn Val Ala Leu Pro Trp
         115                 120                 125

 ttc agc tct gcc tct ggg ccc ctc ctt gcc acc ccc gcg ccc tgc ttc      432
 Phe Ser Ser Ala Ser Gly Pro Leu Leu Ala Thr Pro Ala Pro Cys Phe
     130                 135                 140

 ctg ccc agt cat act gct ccc ccg cta gtg agc gac cct cca ccc aac      480
 Leu Pro Ser His Thr Ala Pro Pro Leu Val Ser Asp Pro Pro Pro Asn
 145                 150                 155                 160

 ccc act gtg gtg gcc ccc agg gtg gtg ggc tcc aga agt ctc cca ggg      528
 Pro Thr Val Val Ala Pro Arg Val Val Gly Ser Arg Ser Leu Pro Gly
                 165                 170                 175

 gca ggc tcc aaa gac tgt ccg cct cct tcc cat gcc ctc ccc gca gca      576
 Ala Gly Ser Lys Asp Cys Pro Pro Pro Ser His Ala Leu Pro Ala Ala
             180                 185                 190

 gca gca ggc gag agt ggc gat gca ggg cca ggg tct gga gca gca gag      624
 Ala Ala Gly Glu Ser Gly Asp Ala Gly Pro Gly Ser Gly Ala Ala Glu
         195                 200                 205

 gtt cct ggc ctg cga gtg ggt cct gcc tgg ctg cac aag ggt ggg aca      672
 Val Pro Gly Leu Arg Val Gly Pro Ala Trp Leu His Lys Gly Gly Thr
     210                 215                 220

 gcg cag tca gcg gcc tcg ggg aca tgg ggc acg ggg ggg gcg ggg cac      720
 Ala Gln Ser Ala Ala Ser Gly Thr Trp Gly Thr Gly Gly Ala Gly His
 225                 230                 235                 240

 agg ggt ccc acc acc gcc act gct gct ccc gca gct gct cct gcc gct      768
 Arg Gly Pro Thr Thr Ala Thr Ala Ala Pro Ala Ala Ala Pro Ala Ala
                 245                 250                 255

 act gcc agc gcg atg gca gca gcc gct cca gac ggt ccg ctg ctg aca      816
 Thr Ala Ser Ala Met Ala Ala Ala Ala Pro Asp Gly Pro Leu Leu Thr
             260                 265                 270

 tca gta cta tca aag tga                                              834
 Ser Val Leu Ser Lys 
         275





      <210> 802
      <211> 501
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(501)

      <400> 802
  atg aca gcc ggg acc gtg gtc atc acc ggg ggc atc ttg gcg act gtg      48
  Met Thr Ala Gly Thr Val Val Ile Thr Gly Gly Ile Leu Ala Thr Val
    1               5                  10                  15

 att ttg ctc tgc atc atc gct gtt ctg tgc tac tgc cgg ctc cag tac       96
 Ile Leu Leu Cys Ile Ile Ala Val Leu Cys Tyr Cys Arg Leu Gln Tyr
              20                  25                  30

 tac tgc tgc aag aag gac gag tcg gag gag gac gag gag gaa cca gac      144
 Tyr Cys Cys Lys Lys Asp Glu Ser Glu Glu Asp Glu Glu Glu Pro Asp
          35                  40                  45

 ttc gcc gtt cac tcg cac ctg ccc ccg ctg cac tcc aac cgc aac ctg      192
 Phe Ala Val His Ser His Leu Pro Pro Leu His Ser Asn Arg Asn Leu
      50                  55                  60

 gtg ctg acc aac ggg ccg gcg ctc tac ccc acc gcc tcc acc tcc ttc      240
 Val Leu Thr Asn Gly Pro Ala Leu Tyr Pro Thr Ala Ser Thr Ser Phe
  65                  70                  75                  80

 agc cag aag tcc ccg cag gcc cgc gcc ctc tgc cgc agc tgc tcc cac      288
 Ser Gln Lys Ser Pro Gln Ala Arg Ala Leu Cys Arg Ser Cys Ser His
                  85                  90                  95

 tgc gag ccc ccc acc ttc ttc ctg cag gag ccg ccg gag gag gaa gag      336
 Cys Glu Pro Pro Thr Phe Phe Leu Gln Glu Pro Pro Glu Glu Glu Glu
             100                 105                 110

 gac gtg ctg aac ggc ggg gag cgc gtg ctc tac aag agc gtg agc cag      384
 Asp Val Leu Asn Gly Gly Glu Arg Val Leu Tyr Lys Ser Val Ser Gln
         115                 120                 125

 gag gac gtg gag ctg ccc cgg ggg gct ttc ggg ggc ctg cag gcg ctc      432
 Glu Asp Val Glu Leu Pro Arg Gly Ala Phe Gly Gly Leu Gln Ala Leu
     130                 135                 140

 aac ccc aac cgc ctc tca gcc atg cgg gag gcc ttc gcc agg agc cgc      480
 Asn Pro Asn Arg Leu Ser Ala Met Arg Glu Ala Phe Ala Arg Ser Arg
 145                 150                 155                 160

 agc atc agc acc gac gtg tga                                          501
 Ser Ile Ser Thr Asp Val 
                 165





      <210> 803
      <211> 729
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(729)

      <400> 803
  atg ctc ctc atc acc ata ctt ggc tac ctc tgt aac act gag ggc atc      48
  Met Leu Leu Ile Thr Ile Leu Gly Tyr Leu Cys Asn Thr Glu Gly Ile
    1               5                  10                  15

 agc ctt act tta aga aag gat gtc gtt cag tcc agc aac ctg ttc ggg       96
 Ser Leu Thr Leu Arg Lys Asp Val Val Gln Ser Ser Asn Leu Phe Gly
              20                  25                  30

 agc ctc cag gag gag cga gcg cag gat gcc gac agt gtg tgg cag cag      144
 Ser Leu Gln Glu Glu Arg Ala Gln Asp Ala Asp Ser Val Trp Gln Gln
          35                  40                  45

 cag cag gcg cat cag cag cac agc tgt acc ttg gat gaa tgt ttt cag      192
 Gln Gln Ala His Gln Gln His Ser Cys Thr Leu Asp Glu Cys Phe Gln
      50                  55                  60

 ttc tac acc aag gag gag cag ctg gcc cag gat gac gcc tgg aag tgt      240
 Phe Tyr Thr Lys Glu Glu Gln Leu Ala Gln Asp Asp Ala Trp Lys Cys
  65                  70                  75                  80

 cct cac tgc caa gtc ctg cag cag ggg atg gtg aag ctg agt ttg tgg      288
 Pro His Cys Gln Val Leu Gln Gln Gly Met Val Lys Leu Ser Leu Trp
                  85                  90                  95

 acg ctg cct gac atc ctc atc atc cac ctc aaa agg ttc tgc cag gtg      336
 Thr Leu Pro Asp Ile Leu Ile Ile His Leu Lys Arg Phe Cys Gln Val
             100                 105                 110

 ggc gag aga aga aac aag ctc tcc acg ctg gtg aag ttt ccg ctc tct      384
 Gly Glu Arg Arg Asn Lys Leu Ser Thr Leu Val Lys Phe Pro Leu Ser
         115                 120                 125

 gga ctc aac atg gct ccc cat gtg gcc cag aga agc acc agc cct gag      432
 Gly Leu Asn Met Ala Pro His Val Ala Gln Arg Ser Thr Ser Pro Glu
     130                 135                 140

 gca gga ctg ggc ccc tgg cct tcc tgg aag cag ccg gac tgc ctg ccc      480
 Ala Gly Leu Gly Pro Trp Pro Ser Trp Lys Gln Pro Asp Cys Leu Pro
 145                 150                 155                 160

 acc agt tac ccg ctg gac ttc ctg tac gac ctg tat gcc gtc tgc aac      528
 Thr Ser Tyr Pro Leu Asp Phe Leu Tyr Asp Leu Tyr Ala Val Cys Asn
                 165                 170                 175

 cac cat ggc aac ctg caa ggt ggg cat tac aca ggt gag cct tgc ctt      576
 His His Gly Asn Leu Gln Gly Gly His Tyr Thr Gly Glu Pro Cys Leu
             180                 185                 190

 gcc ttt ctg caa atg cag ctg tgg cca cag cct cga gat gtc cct gga      624
 Ala Phe Leu Gln Met Gln Leu Trp Pro Gln Pro Arg Asp Val Pro Gly
         195                 200                 205

 atg ggt gtt gct cag atg ctg agc tcc ctg ggg cac tta ttg aga tcc      672
 Met Gly Val Ala Gln Met Leu Ser Ser Leu Gly His Leu Leu Arg Ser
     210                 215                 220

 gac ccc tca ccc acc gca cac cag gaa gat gag gat gag gaa aac aaa      720
 Asp Pro Ser Pro Thr Ala His Gln Glu Asp Glu Asp Glu Glu Asn Lys
 225                 230                 235                 240

 gat gaa taa                                                          729
 Asp Glu 






      <210> 804
      <211> 153
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(153)

      <400> 804
  atg ctg atg ttt cct gga gct ggg atc ttc agg agc ctg tgc ttg gct      48
  Met Leu Met Phe Pro Gly Ala Gly Ile Phe Arg Ser Leu Cys Leu Ala
    1               5                  10                  15

 gtg ccc atc cag tca cca agg agg aac ccc cct act gca gag ctg ctt       96
 Val Pro Ile Gln Ser Pro Arg Arg Asn Pro Pro Thr Ala Glu Leu Leu
              20                  25                  30

 tgg ggc ctc gat gcc att gtt gcc aaa ctg aca ttc cat gat gaa aat      144
 Trp Gly Leu Asp Ala Ile Val Ala Lys Leu Thr Phe His Asp Glu Asn
          35                  40                  45

 gga ctg taa                                                          153
 Gly Leu 
      50





      <210> 805
      <211> 1269
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1269)

      <400> 805
  atg ggt ggc ccc cgg ggc gcg ggc tgg gtg gct gcg ggc ctg ctg ctc      48
  Met Gly Gly Pro Arg Gly Ala Gly Trp Val Ala Ala Gly Leu Leu Leu
    1               5                  10                  15

 ggc gcg ggc gcc tgc tac tgc att tac agg ctg acc cgg ggt cgg cgg       96
 Gly Ala Gly Ala Cys Tyr Cys Ile Tyr Arg Leu Thr Arg Gly Arg Arg
              20                  25                  30

 cgg ggc gac cgc gag ctc ggg ata cgc tct tcg aag tcc gca gaa gac      144
 Arg Gly Asp Arg Glu Leu Gly Ile Arg Ser Ser Lys Ser Ala Glu Asp
          35                  40                  45

 tta act gat ggt tca tat gat gat gtt cta aat gct gaa caa ctt cag      192
 Leu Thr Asp Gly Ser Tyr Asp Asp Val Leu Asn Ala Glu Gln Leu Gln
      50                  55                  60

 aaa ctc ctt tac ctg ctg gag tca act gag gat cct gta att att gaa      240
 Lys Leu Leu Tyr Leu Leu Glu Ser Thr Glu Asp Pro Val Ile Ile Glu
  65                  70                  75                  80

 aga gct ttg att act ttg ggt aac aat gca gcc ttt tca gtt aac caa      288
 Arg Ala Leu Ile Thr Leu Gly Asn Asn Ala Ala Phe Ser Val Asn Gln
                  85                  90                  95

 gct att att cgt gaa ttg ggt ggt att cca att gtt gca aac aaa atc      336
 Ala Ile Ile Arg Glu Leu Gly Gly Ile Pro Ile Val Ala Asn Lys Ile
             100                 105                 110

 aac cat tcc aac cag agt att aaa gac aaa gct tta aat gca cta aat      384
 Asn His Ser Asn Gln Ser Ile Lys Asp Lys Ala Leu Asn Ala Leu Asn
         115                 120                 125

 aac ctg agt gtg aat gtt gaa aat caa atc aag ata aag ata tac atc      432
 Asn Leu Ser Val Asn Val Glu Asn Gln Ile Lys Ile Lys Ile Tyr Ile
     130                 135                 140

 agt caa gta tgt gag gat gtc ttc tct ggt cct ctg aac tct gct gtg      480
 Ser Gln Val Cys Glu Asp Val Phe Ser Gly Pro Leu Asn Ser Ala Val
 145                 150                 155                 160

 cag ctg gcc gga ctg aga ttg ttg aca aac atg act gtt acc aat gac      528
 Gln Leu Ala Gly Leu Arg Leu Leu Thr Asn Met Thr Val Thr Asn Asp
                 165                 170                 175

 cac cag cac atg ctt cac agt tac att aca gac ctg ttc cag gtg tta      576
 His Gln His Met Leu His Ser Tyr Ile Thr Asp Leu Phe Gln Val Leu
             180                 185                 190

 ctt act gga aat gga aac acg aag gtg gat tca tca ttc ctt tcc ctt      624
 Leu Thr Gly Asn Gly Asn Thr Lys Val Asp Ser Ser Phe Leu Ser Leu
         195                 200                 205

 tat gac agc cac gta gca aag gag att ctt ctt cga gta ctt acg cta      672
 Tyr Asp Ser His Val Ala Lys Glu Ile Leu Leu Arg Val Leu Thr Leu
     210                 215                 220

 ttt cag cat ata aag aac tgc ctc aaa ata gaa ggc cat tta gct gtg      720
 Phe Gln His Ile Lys Asn Cys Leu Lys Ile Glu Gly His Leu Ala Val
 225                 230                 235                 240

 cag cct act ttc act gaa ggt tca ttg ttt ttc ctg tta cat gga gaa      768
 Gln Pro Thr Phe Thr Glu Gly Ser Leu Phe Phe Leu Leu His Gly Glu
                 245                 250                 255

 gaa tgt gcc cag aaa ata aga gct tta gtt gat cac cat gat gca gag      816
 Glu Cys Ala Gln Lys Ile Arg Ala Leu Val Asp His His Asp Ala Glu
             260                 265                 270

 ggc agt gca gaa gga aaa tat gag ggg ttg gag ccc cca aat aca gtc      864
 Gly Ser Ala Glu Gly Lys Tyr Glu Gly Leu Glu Pro Pro Asn Thr Val
         275                 280                 285

 ccc act ggg gca ctg cct agt gaa gct gtg aga aga ggg cca cca tcc      912
 Pro Thr Gly Ala Leu Pro Ser Glu Ala Val Arg Arg Gly Pro Pro Ser
     290                 295                 300

 tct aga ccc aag aat agt aga tcc aca gac agc ttg cac tgt gca cct      960
 Ser Arg Pro Lys Asn Ser Arg Ser Thr Asp Ser Leu His Cys Ala Pro
 305                 310                 315                 320

 gca aaa gcc aca gac cct caa cat cat cct gtg aaa gca gct ggg aat     1008
 Ala Lys Ala Thr Asp Pro Gln His His Pro Val Lys Ala Ala Gly Asn
                 325                 330                 335

 gag act gta ccc tgc aaa gca cca ggg gca gag ctt ccc aag gcc atg     1056
 Glu Thr Val Pro Cys Lys Ala Pro Gly Ala Glu Leu Pro Lys Ala Met
             340                 345                 350

 ggg gga gcc cac gtc ttg cat cag tgt gac ctg gat gtg tgt gac cta     1104
 Gly Gly Ala His Val Leu His Gln Cys Asp Leu Asp Val Cys Asp Leu
         355                 360                 365

 cac ggc aca ctg atg caa agg gtg ggc tcc caa ggc ctt ggc agc ttc     1152
 His Gly Thr Leu Met Gln Arg Val Gly Ser Gln Gly Leu Gly Ser Phe
     370                 375                 380

 aac gct gtg gct ctg cag ggc ata gcc cct gtg gct atg ttg agc acc     1200
 Asn Ala Val Ala Leu Gln Gly Ile Ala Pro Val Ala Met Leu Ser Thr
 385                 390                 395                 400

 tgc agc ttt tcc agg tgc aca atg caa gct gtc aat aga tct acc act     1248
 Cys Ser Phe Ser Arg Cys Thr Met Gln Ala Val Asn Arg Ser Thr Thr
                 405                 410                 415

 ctt gca tct aga gga tca tag                                         1269
 Leu Ala Ser Arg Gly Ser 
             420





      <210> 806
      <211> 570
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(570)

      <400> 806
  atg ggt ttt gta gtg tat ccc ctc tgc caa ctc ctt ccc cac tcc acc      48
  Met Gly Phe Val Val Tyr Pro Leu Cys Gln Leu Leu Pro His Ser Thr
    1               5                  10                  15

 ctt aca gtt gat ttt act tgc tta gtc aca tac aga gtt tca gga gaa       96
 Leu Thr Val Asp Phe Thr Cys Leu Val Thr Tyr Arg Val Ser Gly Glu
              20                  25                  30

 tct agg gca ccc cat ccc atg gca gag ctt ttc ctg gtc att tat cac      144
 Ser Arg Ala Pro His Pro Met Ala Glu Leu Phe Leu Val Ile Tyr His
          35                  40                  45

 atg gaa gag aag ttg gag aca cac ata ccc cgc aag caa gag aga gtg      192
 Met Glu Glu Lys Leu Glu Thr His Ile Pro Arg Lys Gln Glu Arg Val
      50                  55                  60

 gag gag aag ggg cca tgc atc tgt aag gca ctg tcc cca aat tct gtt      240
 Glu Glu Lys Gly Pro Cys Ile Cys Lys Ala Leu Ser Pro Asn Ser Val
  65                  70                  75                  80

 aat cag gat tcc aaa aat ggt gga tgc ttt cac atg agc cag gtg ggc      288
 Asn Gln Asp Ser Lys Asn Gly Gly Cys Phe His Met Ser Gln Val Gly
                  85                  90                  95

 ata cgg gag aga aag agc atg aaa atg att tcc tat cat cca tct cct      336
 Ile Arg Glu Arg Lys Ser Met Lys Met Ile Ser Tyr His Pro Ser Pro
             100                 105                 110

 cac tcc cat cca aag agg tca tcc atg gat gac cat gtt cac tac cat      384
 His Ser His Pro Lys Arg Ser Ser Met Asp Asp His Val His Tyr His
         115                 120                 125

 tta tcc att gaa gac ttg tgg gtc act ctc tgc ctc acc acc tcc att      432
 Leu Ser Ile Glu Asp Leu Trp Val Thr Leu Cys Leu Thr Thr Ser Ile
     130                 135                 140

 tct acc ttc att cat gat gat ttc aaa atc caa ctg ctg aca ttc act      480
 Ser Thr Phe Ile His Asp Asp Phe Lys Ile Gln Leu Leu Thr Phe Thr
 145                 150                 155                 160

 gat tat ttc act aac aaa cag aac tac cac aag aag tgc cta cct tct      528
 Asp Tyr Phe Thr Asn Lys Gln Asn Tyr His Lys Lys Cys Leu Pro Ser
                 165                 170                 175

 cca acc ccc caa act ata aac tta ccc aat agc tat aac taa              570
 Pro Thr Pro Gln Thr Ile Asn Leu Pro Asn Ser Tyr Asn 
             180                 185





      <210> 807
      <211> 414
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(414)

      <400> 807
  atg gct ctg ccg ctt gcc agc tgg gtg gct ctg ggg cag tgg ctg ctg      48
  Met Ala Leu Pro Leu Ala Ser Trp Val Ala Leu Gly Gln Trp Leu Leu
    1               5                  10                  15

 ctg ccc gcc cta cag gcc atg tca gta gag aac cgc ttt cct gcc ccc       96
 Leu Pro Ala Leu Gln Ala Met Ser Val Glu Asn Arg Phe Pro Ala Pro
              20                  25                  30

 atc ttt ccc caa agg cag gca gca tgg aat gac ttt ggg gaa atg acc      144
 Ile Phe Pro Gln Arg Gln Ala Ala Trp Asn Asp Phe Gly Glu Met Thr
          35                  40                  45

 ttt gtc cag ctg tgc cga gcc tgc aga tct tcc agc tca tcc cca acg      192
 Phe Val Gln Leu Cys Arg Ala Cys Arg Ser Ser Ser Ser Ser Pro Thr
      50                  55                  60

 gcc att gtc acc ctg gtt acc caa gac gaa gat tca att tcc ctt tct      240
 Ala Ile Val Thr Leu Val Thr Gln Asp Glu Asp Ser Ile Ser Leu Ser
  65                  70                  75                  80

 cct aat aac aaa aac tat aac agt aat ata aca att gct gcc att ccc      288
 Pro Asn Asn Lys Asn Tyr Asn Ser Asn Ile Thr Ile Ala Ala Ile Pro
                  85                  90                  95

 cag acc aca agc tcc ata agc cca cgg tgg tgt tta gat cca aca caa      336
 Gln Thr Thr Ser Ser Ile Ser Pro Arg Trp Cys Leu Asp Pro Thr Gln
             100                 105                 110

 ggc ctc gca tac cgc tgt cac tcc gag aat gtt tgc cga atg aat gaa      384
 Gly Leu Ala Tyr Arg Cys His Ser Glu Asn Val Cys Arg Met Asn Glu
         115                 120                 125

 cgg tcc cat ttt gct tct ggg gaa aat taa                              414
 Arg Ser His Phe Ala Ser Gly Glu Asn 
     130                 135





      <210> 808
      <211> 1206
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1206)

      <400> 808
  atg ggc cta ttt gga ttt tgg agg aaa tat att cct cat ttg ggt gtg      48
  Met Gly Leu Phe Gly Phe Trp Arg Lys Tyr Ile Pro His Leu Gly Val
    1               5                  10                  15

 tta cta tgg ccc att tat caa gtg aac cga aaa gct gct ggt ttt gag       96
 Leu Leu Trp Pro Ile Tyr Gln Val Asn Arg Lys Ala Ala Gly Phe Glu
              20                  25                  30

 tgg tgt cca gaa cag gag aca gct ctt caa cag gtc cag gct gct gtg      144
 Trp Cys Pro Glu Gln Glu Thr Ala Leu Gln Gln Val Gln Ala Ala Val
          35                  40                  45

 cag gct gct ctg caa ctt ggg cca tat gac tca gca gat cca atg gtg      192
 Gln Ala Ala Leu Gln Leu Gly Pro Tyr Asp Ser Ala Asp Pro Met Val
      50                  55                  60

 ctt gag gtg tca gtg gca gat atg gat gct gtt tgg agc ctt tgg cag      240
 Leu Glu Val Ser Val Ala Asp Met Asp Ala Val Trp Ser Leu Trp Gln
  65                  70                  75                  80

 gcc ccg ata ggt gaa tta cca cag agg cct cta gga ttt tgg agc aag      288
 Ala Pro Ile Gly Glu Leu Pro Gln Arg Pro Leu Gly Phe Trp Ser Lys
                  85                  90                  95

 gcc ctg ccc tct tct gca gat aac gac tct cat ttt gag gga cag ctc      336
 Ala Leu Pro Ser Ser Ala Asp Asn Asp Ser His Phe Glu Gly Gln Leu
             100                 105                 110

 ttg gcc tgt tac tgg gct ttg gtg gaa act cag tgt ttg act atg ggt      384
 Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Gln Cys Leu Thr Met Gly
         115                 120                 125

 tat caa gtc atc atg caa cct aaa ctg cct att atg aac tgt gtg ctt      432
 Tyr Gln Val Ile Met Gln Pro Lys Leu Pro Ile Met Asn Cys Val Leu
     130                 135                 140

 ttt gag cca tct agc cat aaa gtg gaa tgc aca gca gca ttc cat cat      480
 Phe Glu Pro Ser Ser His Lys Val Glu Cys Thr Ala Ala Phe His His
 145                 150                 155                 160

 caa atg gaa gtg gta tat atg act tcc ctg aag gac agc ggt gaa ggg      528
 Gln Met Glu Val Val Tyr Met Thr Ser Leu Lys Asp Ser Gly Glu Gly
                 165                 170                 175

 aaa tct tcc cag tgg gca gaa ctt cga gca gtg cac ctg gtt gtg cac      576
 Lys Ser Ser Gln Trp Ala Glu Leu Arg Ala Val His Leu Val Val His
             180                 185                 190

 ttt gca tgg aag gag aaa tgg cct gat gtg cga tta tat act cat aca      624
 Phe Ala Trp Lys Glu Lys Trp Pro Asp Val Arg Leu Tyr Thr His Thr
         195                 200                 205

 tgg gtt gta gcc agt ggt ttg gct gga tgg tca ggg act tgg aag aag      672
 Trp Val Val Ala Ser Gly Leu Ala Gly Trp Ser Gly Thr Trp Lys Lys
     210                 215                 220

 cat tac tgg aaa att ggt gac aaa gaa att tgg gga aga ggg aaa ggg      720
 His Tyr Trp Lys Ile Gly Asp Lys Glu Ile Trp Gly Arg Gly Lys Gly
 225                 230                 235                 240

 cag aag ttt gtg ttc act gaa ata gac aca tac tcc aga tat ggg ttt      768
 Gln Lys Phe Val Phe Thr Glu Ile Asp Thr Tyr Ser Arg Tyr Gly Phe
                 245                 250                 255

 gtc tat tat gca cgc aat gct tct gcc aag act acc atc gtg gac tca      816
 Val Tyr Tyr Ala Arg Asn Ala Ser Ala Lys Thr Thr Ile Val Asp Ser
             260                 265                 270

 tgg aat acc tta tcc acc atc atg gta ttc cac cca gca ttc tct ctg      864
 Trp Asn Thr Leu Ser Thr Ile Met Val Phe His Pro Ala Phe Ser Leu
         275                 280                 285

 acc aag gca ctg act tta tgg cta cag aag tgt ggc agc agg att cat      912
 Thr Lys Ala Leu Thr Leu Trp Leu Gln Lys Cys Gly Ser Arg Ile His
     290                 295                 300

 ggg tcc agg aat caa ggg gtg gaa ttg gaa gtg gca cca ccc atc atc      960
 Gly Ser Arg Asn Gln Gly Val Glu Leu Glu Val Ala Pro Pro Ile Ile
 305                 310                 315                 320

 atc cct agt gat cca tta gca aaa tac ttg ctt cct gtt ccc agt aca     1008
 Ile Pro Ser Asp Pro Leu Ala Lys Tyr Leu Leu Pro Val Pro Ser Thr
                 325                 330                 335

 tta tgt tct gct ggc ttg gag gtc tta att cca gag gga gga atg ctg     1056
 Leu Cys Ser Ala Gly Leu Glu Val Leu Ile Pro Glu Gly Gly Met Leu
             340                 345                 350

 cca cca gga gac aca aca atg att cca tta aac tgg aaa tta aga ttg     1104
 Pro Pro Gly Asp Thr Thr Met Ile Pro Leu Asn Trp Lys Leu Arg Leu
         355                 360                 365

 cca cct cga cac ttt ggg ctc tcc cta cct tta agt caa cag gct aag     1152
 Pro Pro Arg His Phe Gly Leu Ser Leu Pro Leu Ser Gln Gln Ala Lys
     370                 375                 380

 aag gga gtt aca gtg ttg gct ggg gtt att gac cca gac tac caa gat     1200
 Lys Gly Val Thr Val Leu Ala Gly Val Ile Asp Pro Asp Tyr Gln Asp
 385                 390                 395                 400

 gaa tga                                                             1206
 Glu 






      <210> 809
      <211> 672
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(672)

      <400> 809
  atg gac ttc aaa ggc gat tgt agt cta gac tac aaa ctg gtg agc cag      48
  Met Asp Phe Lys Gly Asp Cys Ser Leu Asp Tyr Lys Leu Val Ser Gln
    1               5                  10                  15

 cta tgg ctg gca gtg gtt gtg gtg ccc ctt gct gtc tca gtc gcc tgc       96
 Leu Trp Leu Ala Val Val Val Val Pro Leu Ala Val Ser Val Ala Cys
              20                  25                  30

 ctg aac tct gat tgt cac atg gcc aca gcg ctg cct ctt ggg cct gga      144
 Leu Asn Ser Asp Cys His Met Ala Thr Ala Leu Pro Leu Gly Pro Gly
          35                  40                  45

 gcc tca ggt ctc ctc act ggg act gtc act ctg gag ctt cgc aga gca      192
 Ala Ser Gly Leu Leu Thr Gly Thr Val Thr Leu Glu Leu Arg Arg Ala
      50                  55                  60

 ccc cgc ctt tgg aag cat gct ggc ttg ctg gtg ctg gaa ctc agt gct      240
 Pro Arg Leu Trp Lys His Ala Gly Leu Leu Val Leu Glu Leu Ser Ala
  65                  70                  75                  80

 gag gcc ttc acc cta ggg gga gtg ctg gtc tca gtg cac gcc cta ttc      288
 Glu Ala Phe Thr Leu Gly Gly Val Leu Val Ser Val His Ala Leu Phe
                  85                  90                  95

 ttg ctg agc cag agg aaa cca gga tgc tgc agg agc cag agt ctg cac      336
 Leu Leu Ser Gln Arg Lys Pro Gly Cys Cys Arg Ser Gln Ser Leu His
             100                 105                 110

 tat caa gag ctg cag gag gag tgc ccc agt tcc cct ttc gat cca tct      384
 Tyr Gln Glu Leu Gln Glu Glu Cys Pro Ser Ser Pro Phe Asp Pro Ser
         115                 120                 125

 cct ttc tac tgt agc gga gac tac aag tcc cag gat gcc ccg cta gcc      432
 Pro Phe Tyr Cys Ser Gly Asp Tyr Lys Ser Gln Asp Ala Pro Leu Ala
     130                 135                 140

 cgt gac cgg cta gga aat aaa gag cct tct ctc cgc gga ctg gag gct      480
 Arg Asp Arg Leu Gly Asn Lys Glu Pro Ser Leu Arg Gly Leu Glu Ala
 145                 150                 155                 160

 gcc acc act gac atg ttc cac cag att ctt gtt ggg ctc aag aag cat      528
 Ala Thr Thr Asp Met Phe His Gln Ile Leu Val Gly Leu Lys Lys His
                 165                 170                 175

 tca agc ttc atc ccc ctt cgt att tat gaa atc cgg agg tac tgg agc      576
 Ser Ser Phe Ile Pro Leu Arg Ile Tyr Glu Ile Arg Arg Tyr Trp Ser
             180                 185                 190

 agc gct aaa ttc aac gta gtt atg aaa cac ata cga agc atc tta tat      624
 Ser Ala Lys Phe Asn Val Val Met Lys His Ile Arg Ser Ile Leu Tyr
         195                 200                 205

 aac ttg gct agt tct cag ttt tgt ttc ttg ctg agc tat tcg gcc tag      672
 Asn Leu Ala Ser Ser Gln Phe Cys Phe Leu Leu Ser Tyr Ser Ala 
     210                 215                 220





      <210> 810
      <211> 519
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(519)

      <400> 810
  atg act atg agt cag tgt ttc aaa gca atc ctg att ctc aca gca cag      48
  Met Thr Met Ser Gln Cys Phe Lys Ala Ile Leu Ile Leu Thr Ala Gln
    1               5                  10                  15

 ctc ttg gtg att ata tct tgg atg aga gac aag gaa gag ctc tca aac       96
 Leu Leu Val Ile Ile Ser Trp Met Arg Asp Lys Glu Glu Leu Ser Asn
              20                  25                  30

 ttt cac cag agc atc agc aga cac cag gaa aat gtg ccc tgt gaa cac      144
 Phe His Gln Ser Ile Ser Arg His Gln Glu Asn Val Pro Cys Glu His
          35                  40                  45

 atc ccc ttg gag ccc act ggc agc gga gac aga cgt gat ata tca caa      192
 Ile Pro Leu Glu Pro Thr Gly Ser Gly Asp Arg Arg Asp Ile Ser Gln
      50                  55                  60

 ctg cag gaa gct aaa gga atc aaa tgg aac aat gtt gct ctc ctt tgg      240
 Leu Gln Glu Ala Lys Gly Ile Lys Trp Asn Asn Val Ala Leu Leu Trp
  65                  70                  75                  80

 aaa ata ggg ctc tgc tca ctt aat ctg cct ggc tca tgg ccc tgt gtg      288
 Lys Ile Gly Leu Cys Ser Leu Asn Leu Pro Gly Ser Trp Pro Cys Val
                  85                  90                  95

 aca gtg ttg gaa agt ggc ctg cag ggc atc tct aca ttt ggt gag gaa      336
 Thr Val Leu Glu Ser Gly Leu Gln Gly Ile Ser Thr Phe Gly Glu Glu
             100                 105                 110

 act gaa gca cag gac aca cat aac cta agc agc caa agg gtc tgc atg      384
 Thr Glu Ala Gln Asp Thr His Asn Leu Ser Ser Gln Arg Val Cys Met
         115                 120                 125

 ctc tgt gcc gaa tgc tat gca gcc aat gaa gtg ctg cga gat gtc ttc      432
 Leu Cys Ala Glu Cys Tyr Ala Ala Asn Glu Val Leu Arg Asp Val Phe
     130                 135                 140

 agg acc ctg gaa cgc tac atc ttt gcc ttg atg gcc tcg ctg cat ctc      480
 Arg Thr Leu Glu Arg Tyr Ile Phe Ala Leu Met Ala Ser Leu His Leu
 145                 150                 155                 160

 ttc cct ctg ggt cag aag cct tcg gaa ggg aga ttc taa                  519
 Phe Pro Leu Gly Gln Lys Pro Ser Glu Gly Arg Phe 
                 165                 170





      <210> 811
      <211> 705
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(705)

      <400> 811
  atg ggc atc ttc atg gtt gtt ggg aag ctg tta gtc ccc aga act aga      48
  Met Gly Ile Phe Met Val Val Gly Lys Leu Leu Val Pro Arg Thr Arg
    1               5                  10                  15

 gca agt ggg gcc agt agg tac aat tct cag ata tgg tgg cct ttg aag       96
 Ala Ser Gly Ala Ser Arg Tyr Asn Ser Gln Ile Trp Trp Pro Leu Lys
              20                  25                  30

 cag ctc aag tca gct gac acc ttt cct ttc ttc cct tcc ctt ctc cat      144
 Gln Leu Lys Ser Ala Asp Thr Phe Pro Phe Phe Pro Ser Leu Leu His
          35                  40                  45

 gaa ctt gca cgg agt cgc tgg cgg att cat cat aca tac tgt gaa gcc      192
 Glu Leu Ala Arg Ser Arg Trp Arg Ile His His Thr Tyr Cys Glu Ala
      50                  55                  60

 tcg aaa tgc cta gag tct aat aaa tta gac tta ata tac cta ctt gtt      240
 Ser Lys Cys Leu Glu Ser Asn Lys Leu Asp Leu Ile Tyr Leu Leu Val
  65                  70                  75                  80

 gat cca gaa tgc att gca agg atc ttg tat tgt ctc cgg gtt gac atg      288
 Asp Pro Glu Cys Ile Ala Arg Ile Leu Tyr Cys Leu Arg Val Asp Met
                  85                  90                  95

 ttg aat gtt gct tgt cag ata tcg ggt gct gaa aag gcc tgt gcc cag      336
 Leu Asn Val Ala Cys Gln Ile Ser Gly Ala Glu Lys Ala Cys Ala Gln
             100                 105                 110

 tat gtg gta atg gtt gag tct gga ggg gtt gga tgg aag tgg ttg ggg      384
 Tyr Val Val Met Val Glu Ser Gly Gly Val Gly Trp Lys Trp Leu Gly
         115                 120                 125

 aat agg cag agc ttt tat ttg tct gag ctt acc cag ctg gtt att ggc      432
 Asn Arg Gln Ser Phe Tyr Leu Ser Glu Leu Thr Gln Leu Val Ile Gly
     130                 135                 140

 aaa gca aag act gga ctt gat tcc ctg tcc aca gaa aag ggt aga aag      480
 Lys Ala Lys Thr Gly Leu Asp Ser Leu Ser Thr Glu Lys Gly Arg Lys
 145                 150                 155                 160

 ttg ctg aca ata gag ggc tct gtg gtc aga gga gaa gtt cag agg tct      528
 Leu Leu Thr Ile Glu Gly Ser Val Val Arg Gly Glu Val Gln Arg Ser
                 165                 170                 175

 gtg ctc aga aag gag aaa ctc act gag cgg att tta gaa gct cta gca      576
 Val Leu Arg Lys Glu Lys Leu Thr Glu Arg Ile Leu Glu Ala Leu Ala
             180                 185                 190

 ttt cta ctg ctc cag cat ttg ctc cgc agt tac gtt gtt gtc act tgg      624
 Phe Leu Leu Leu Gln His Leu Leu Arg Ser Tyr Val Val Val Thr Trp
         195                 200                 205

 gct aca gca tcc agt aga ctg atg ttc agg gct ctc ctg cag act gct      672
 Ala Thr Ala Ser Ser Arg Leu Met Phe Arg Ala Leu Leu Gln Thr Ala
     210                 215                 220

 gct gcc cgt ggt agc aca gcc cag ctg act tga                          705
 Ala Ala Arg Gly Ser Thr Ala Gln Leu Thr 
 225                 230





      <210> 812
      <211> 366
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(366)

      <400> 812
  atg ccg gga ctc acg tgc gct ccg gtg gac ggg gcg gtg ctg gtg agg      48
  Met Pro Gly Leu Thr Cys Ala Pro Val Asp Gly Ala Val Leu Val Arg
    1               5                  10                  15

 gtt ttt cta gga ctg cta gtc cag cac cgt ctc gtc ttg gac ttt gaa       96
 Val Phe Leu Gly Leu Leu Val Gln His Arg Leu Val Leu Asp Phe Glu
              20                  25                  30

 aat gat ttt agg gta ctg gtg ccc act gtc tgc aag gtg ccc act gtc      144
 Asn Asp Phe Arg Val Leu Val Pro Thr Val Cys Lys Val Pro Thr Val
          35                  40                  45

 tgc agg gtg ccc act gtc tgc aag gtg ccc agt gtc tgc aag ggt gca      192
 Cys Arg Val Pro Thr Val Cys Lys Val Pro Ser Val Cys Lys Gly Ala
      50                  55                  60

 tgt gac aaa gtc atc cct gct tca gtt ggg gtg gag gat gat agt gac      240
 Cys Asp Lys Val Ile Pro Ala Ser Val Gly Val Glu Asp Asp Ser Asp
  65                  70                  75                  80

 gtc cat gag agg tgt gat gtt gct tca ggg gta gca tct tac gcc cca      288
 Val His Glu Arg Cys Asp Val Ala Ser Gly Val Ala Ser Tyr Ala Pro
                  85                  90                  95

 agg acg act gac ctc tta gtt tac ctg aca ccc tca gag acg gct gaa      336
 Arg Thr Thr Asp Leu Leu Val Tyr Leu Thr Pro Ser Glu Thr Ala Glu
             100                 105                 110

 ttt gct cag cca gtg gtt cga aac ggc tga                              366
 Phe Ala Gln Pro Val Val Arg Asn Gly 
         115                 120





      <210> 813
      <211> 483
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(483)

      <400> 813
  atg gcg cgc ctg ggc gct gtg cgc tcc cac tac tgc gcc ctg ctg ctg      48
  Met Ala Arg Leu Gly Ala Val Arg Ser His Tyr Cys Ala Leu Leu Leu
    1               5                  10                  15

 gcc gcg gcg ctg gcc gtc tgc gcc ttc tac tac ctc ggc tca ggc cgg       96
 Ala Ala Ala Leu Ala Val Cys Ala Phe Tyr Tyr Leu Gly Ser Gly Arg
              20                  25                  30

 gag acc ttc tcc agc gcc acc aag agg ctg aag gag gcc cgc gcc ggg      144
 Glu Thr Phe Ser Ser Ala Thr Lys Arg Leu Lys Glu Ala Arg Ala Gly
          35                  40                  45

 gct ccc gcc gcg ccc tcg ccg ccc gcg ctg gag cta gcg cgg ggc tcc      192
 Ala Pro Ala Ala Pro Ser Pro Pro Ala Leu Glu Leu Ala Arg Gly Ser
      50                  55                  60

 gtg gcg cca gcc ccc ggc gcg aag gcc aag agc ttg gag ggc ggc ggt      240
 Val Ala Pro Ala Pro Gly Ala Lys Ala Lys Ser Leu Glu Gly Gly Gly
  65                  70                  75                  80

 gcc ggg ccg gtg gac tac cac ctg ctg atg atg ttc acc aag gcg gag      288
 Ala Gly Pro Val Asp Tyr His Leu Leu Met Met Phe Thr Lys Ala Glu
                  85                  90                  95

 cac aat gcc gcg ctg cag gcc aag gcc cgc gtc gcg ctg cgc tca ctg      336
 His Asn Ala Ala Leu Gln Ala Lys Ala Arg Val Ala Leu Arg Ser Leu
             100                 105                 110

 ctg cgc ctc gcc aag ttc gag gcg cac gag gtg ctt aac ctt cac ttc      384
 Leu Arg Leu Ala Lys Phe Glu Ala His Glu Val Leu Asn Leu His Phe
         115                 120                 125

 gtg agc gag gag gcc agc cgc gag gtg gcc aag ggc ctg ctg cgg gag      432
 Val Ser Glu Glu Ala Ser Arg Glu Val Ala Lys Gly Leu Leu Arg Glu
     130                 135                 140

 ctc ctg ccg ccc gcc gct ggc ttc aag tgc aag ctc ccg ctg cag cgc      480
 Leu Leu Pro Pro Ala Ala Gly Phe Lys Cys Lys Leu Pro Leu Gln Arg
 145                 150                 155                 160

 tag                                                                  483
 






      <210> 814
      <211> 987
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(987)

      <400> 814
  atg gct gct ctc ctg ctc ttg gac ctt cag ggg ctc tct gct gcc ctc      48
  Met Ala Ala Leu Leu Leu Leu Asp Leu Gln Gly Leu Ser Ala Ala Leu
    1               5                  10                  15

 agg agt ggg ccc ggc tat tct cct cac cct cac aac ttc ctg aga agt       96
 Arg Ser Gly Pro Gly Tyr Ser Pro His Pro His Asn Phe Leu Arg Ser
              20                  25                  30

 gat agc atg ctg cgc tca gtg gcc tgg tgg ctc tcc agt ccc cgt gcc      144
 Asp Ser Met Leu Arg Ser Val Ala Trp Trp Leu Ser Ser Pro Arg Ala
          35                  40                  45

 cag tgc aaa cca gcg gag gat gcc agc tca agt ttc tgg gga cga aac      192
 Gln Cys Lys Pro Ala Glu Asp Ala Ser Ser Ser Phe Trp Gly Arg Asn
      50                  55                  60

 agg cag acc tcc ggg cct ggc ttg gga tcc cag tgg cac ccc agg atc      240
 Arg Gln Thr Ser Gly Pro Gly Leu Gly Ser Gln Trp His Pro Arg Ile
  65                  70                  75                  80

 acc cca tgt tcg ctg gct ctt tct tta aac tgt gtt cta gaa gca tcc      288
 Thr Pro Cys Ser Leu Ala Leu Ser Leu Asn Cys Val Leu Glu Ala Ser
                  85                  90                  95

 tct ggg cca gtt aag tca gtg cca aaa gat gcc tgc ctc tgc acc agg      336
 Ser Gly Pro Val Lys Ser Val Pro Lys Asp Ala Cys Leu Cys Thr Arg
             100                 105                 110

 ccc gtg ggt cta cac ctg agt ttt ggt gat cag cca gcc atc cct gct      384
 Pro Val Gly Leu His Leu Ser Phe Gly Asp Gln Pro Ala Ile Pro Ala
         115                 120                 125

 ggc tct ggt ggt gtg gaa atg gga aag gat tcc ctt gag aaa aaa gag      432
 Gly Ser Gly Gly Val Glu Met Gly Lys Asp Ser Leu Glu Lys Lys Glu
     130                 135                 140

 aga aag ggt ctc ctg tgc tgc ttc ctc aca gca ggt cag agc ttg gct      480
 Arg Lys Gly Leu Leu Cys Cys Phe Leu Thr Ala Gly Gln Ser Leu Ala
 145                 150                 155                 160

 tgg agg aag ctg aaa ccc ttc aga gag gct gga cca agc agt gga caa      528
 Trp Arg Lys Leu Lys Pro Phe Arg Glu Ala Gly Pro Ser Ser Gly Gln
                 165                 170                 175

 cgg ctg ggg aga caa gta gaa gtt gtt tct gtt ttc ttg gag gcc agg      576
 Arg Leu Gly Arg Gln Val Glu Val Val Ser Val Phe Leu Glu Ala Arg
             180                 185                 190

 cta atg gtg cag tac atg gct ggc ata caa cag gtg ctc gat aag tgg      624
 Leu Met Val Gln Tyr Met Ala Gly Ile Gln Gln Val Leu Asp Lys Trp
         195                 200                 205

 tgg gtg aat aga aca gat gca aag ctc aag gat tcc aga gga ggc gtg      672
 Trp Val Asn Arg Thr Asp Ala Lys Leu Lys Asp Ser Arg Gly Gly Val
     210                 215                 220

 gag gga atg aca att aga ggt ggc ttt gaa gag gag gac tat ttg act      720
 Glu Gly Met Thr Ile Arg Gly Gly Phe Glu Glu Glu Asp Tyr Leu Thr
 225                 230                 235                 240

 tgg gct ttg aag aat gca gag gag ttt tct ccc cca cgg gca gag ctc      768
 Trp Ala Leu Lys Asn Ala Glu Glu Phe Ser Pro Pro Arg Ala Glu Leu
                 245                 250                 255

 tcc tac cca gat agg tct gca tct cag ggc tct gtg tac agc agg cac      816
 Ser Tyr Pro Asp Arg Ser Ala Ser Gln Gly Ser Val Tyr Ser Arg His
             260                 265                 270

 aca tca gga ccc gct atg gca atc cgg gac agt ttc cct ctt tgc ccg      864
 Thr Ser Gly Pro Ala Met Ala Ile Arg Asp Ser Phe Pro Leu Cys Pro
         275                 280                 285

 cct cct gct gag gcc ttc aac acc tct gga gga agg gct gct aca gtc      912
 Pro Pro Ala Glu Ala Phe Asn Thr Ser Gly Gly Arg Ala Ala Thr Val
     290                 295                 300

 aag tct tca gga gaa agc aag aag gac cca ggt act gtg gcc tgc cgc      960
 Lys Ser Ser Gly Glu Ser Lys Lys Asp Pro Gly Thr Val Ala Cys Arg
 305                 310                 315                 320

 ggc cct gaa agc ttc tcg atg ccg tga                                  987
 Gly Pro Glu Ser Phe Ser Met Pro 
                 325





      <210> 815
      <211> 390
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(390)

      <400> 815
  atg gaa agc tgc ttc ctg ctg tgg ctt gcg cag atg ctg gta gag tcc      48
  Met Glu Ser Cys Phe Leu Leu Trp Leu Ala Gln Met Leu Val Glu Ser
    1               5                  10                  15

 agc cat gca gct cgc atg cac tca tca ttc cag agg cag cat cgc cgc       96
 Ser His Ala Ala Arg Met His Ser Ser Phe Gln Arg Gln His Arg Arg
              20                  25                  30

 aga atg cga gtt cgc ctt tat agg gag tct gcc cag gtc atg cag cac      144
 Arg Met Arg Val Arg Leu Tyr Arg Glu Ser Ala Gln Val Met Gln His
          35                  40                  45

 tgg ctc agg gta ccc acg gca gca aag cag ctg cac caa gat gca ggt      192
 Trp Leu Arg Val Pro Thr Ala Ala Lys Gln Leu His Gln Asp Ala Gly
      50                  55                  60

 gcc aca ggg tca cac caa cgc agc aca atg gcg ctt ccc agc acc gca      240
 Ala Thr Gly Ser His Gln Arg Ser Thr Met Ala Leu Pro Ser Thr Ala
  65                  70                  75                  80

 gcc acc aag gcc ctc ctg gaa ctg aca ttg ctg ctg gcc gca gac gtg      288
 Ala Thr Lys Ala Leu Leu Glu Leu Thr Leu Leu Leu Ala Ala Asp Val
                  85                  90                  95

 gcc tca aac ccg tcg ccc cag cag caa tcc aca agc aca gcg tac atc      336
 Ala Ser Asn Pro Ser Pro Gln Gln Gln Ser Thr Ser Thr Ala Tyr Ile
             100                 105                 110

 cct ccc tcc gtg gaa cta aga atg gag gct att ttc aga gaa gct gtc      384
 Pro Pro Ser Val Glu Leu Arg Met Glu Ala Ile Phe Arg Glu Ala Val
         115                 120                 125

 cac taa                                                              390
 His 






      <210> 816
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 816
  atg ggg gaa aac ttg ctg agg ctc cta ctg gcc aag att aca tta tta      48
  Met Gly Glu Asn Leu Leu Arg Leu Leu Leu Ala Lys Ile Thr Leu Leu
    1               5                  10                  15

 gat cgt ctt caa gga gaa caa ggt aga agg atg aat cgt gag aac aaa       96
 Asp Arg Leu Gln Gly Glu Gln Gly Arg Arg Met Asn Arg Glu Asn Lys
              20                  25                  30

 agt gaa gct ttc tcc ttg cct agc acg cag agg gac atc ccc cat tac      144
 Ser Glu Ala Phe Ser Leu Pro Ser Thr Gln Arg Asp Ile Pro His Tyr
          35                  40                  45

 caa gga gca gaa gaa gca gtc tcc ata gaa cat ttg tct cgc caa gat      192
 Gln Gly Ala Glu Glu Ala Val Ser Ile Glu His Leu Ser Arg Gln Asp
      50                  55                  60

 ctg aaa gtg aaa gga aaa gag aga gga gga gga gga gga ggg aag aaa      240
 Leu Lys Val Lys Gly Lys Glu Arg Gly Gly Gly Gly Gly Gly Lys Lys
  65                  70                  75                  80

 aga aga aga aaa agg agg agg agg tgg aaa gaa aga aag aaa aga aaa      288
 Arg Arg Arg Lys Arg Arg Arg Arg Trp Lys Glu Arg Lys Lys Arg Lys
                  85                  90                  95

 gaa aag aga aag aaa gag gaa gag gag gaa gag gaa gaa gaa cca gat      336
 Glu Lys Arg Lys Lys Glu Glu Glu Glu Glu Glu Glu Glu Glu Pro Asp
             100                 105                 110

 gga gaa aaa gaa caa gaa atg gca gct tca tgc cac ctc agc tgt cct      384
 Gly Glu Lys Glu Gln Glu Met Ala Ala Ser Cys His Leu Ser Cys Pro
         115                 120                 125

 gaa gga tag                                                          393
 Glu Gly 
     130





      <210> 817
      <211> 216
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(216)

      <400> 817
  atg cag gcc ggg caa cct tgg ctt gtt cat ctc cct ttg ctg cca gca      48
  Met Gln Ala Gly Gln Pro Trp Leu Val His Leu Pro Leu Leu Pro Ala
    1               5                  10                  15

 gcc tcc ata tgg cag aca ttc ttc tcc tgg ggg gct gac agc cat gga       96
 Ala Ser Ile Trp Gln Thr Phe Phe Ser Trp Gly Ala Asp Ser His Gly
              20                  25                  30

 ggg tgg gga gca ggc ctg agc agg gcg ggt tcc cga aag aca gcc cag      144
 Gly Trp Gly Ala Gly Leu Ser Arg Ala Gly Ser Arg Lys Thr Ala Gln
          35                  40                  45

 aaa gca ggg tca gat agt ggg ggg tgg gtt cag ctc cac tgt cca ggg      192
 Lys Ala Gly Ser Asp Ser Gly Gly Trp Val Gln Leu His Cys Pro Gly
      50                  55                  60

 gtt gag gtt gga gac tgg acc tga                                      216
 Val Glu Val Gly Asp Trp Thr 
  65                  70





      <210> 818
      <211> 747
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(747)

      <400> 818
  atg cag cca gtg tcc att ctg gct ctg tgc tca cac tat tgc ttt ctt      48
  Met Gln Pro Val Ser Ile Leu Ala Leu Cys Ser His Tyr Cys Phe Leu
    1               5                  10                  15

 ttt aaa tta aga atc atg gca aag ata gag ttg tca tct cta aag aag       96
 Phe Lys Leu Arg Ile Met Ala Lys Ile Glu Leu Ser Ser Leu Lys Lys
              20                  25                  30

 aaa ttc aaa gaa gct ccc cat ccc act gaa agc cac ttc tac tgc tca      144
 Lys Phe Lys Glu Ala Pro His Pro Thr Glu Ser His Phe Tyr Cys Ser
          35                  40                  45

 atc aaa tct cca cat tca cca tcc ttc aag gcc atg gga cct gat ttc      192
 Ile Lys Ser Pro His Ser Pro Ser Phe Lys Ala Met Gly Pro Asp Phe
      50                  55                  60

 ttc ctg gat gct gga caa gaa ccc gga aag ttt tct ttg gct gta gat      240
 Phe Leu Asp Ala Gly Gln Glu Pro Gly Lys Phe Ser Leu Ala Val Asp
  65                  70                  75                  80

 tca aat gca gaa gaa gtg tcg gaa ggt tcc ttg ctg agc tta gtc act      288
 Ser Asn Ala Glu Glu Val Ser Glu Gly Ser Leu Leu Ser Leu Val Thr
                  85                  90                  95

 gtg gga gaa cca tgg gat gtc tcc cta gag gag tcc agt ttc ttt aat      336
 Val Gly Glu Pro Trp Asp Val Ser Leu Glu Glu Ser Ser Phe Phe Asn
             100                 105                 110

 ttc tct gac aca gag ctg cct gag ggc ttt gta ggt gta tgt cct gtg      384
 Phe Ser Asp Thr Glu Leu Pro Glu Gly Phe Val Gly Val Cys Pro Val
         115                 120                 125

 gac ttc tcc aaa gtt gtt acc ttc tta ctc act gtg gca gcc gga gct      432
 Asp Phe Ser Lys Val Val Thr Phe Leu Leu Thr Val Ala Ala Gly Ala
     130                 135                 140

 aca aaa cgt cct gca cgt gtg tgc acg cgc aca tac aca cac tct cac      480
 Thr Lys Arg Pro Ala Arg Val Cys Thr Arg Thr Tyr Thr His Ser His
 145                 150                 155                 160

 aca aat acc aaa ctt gaa ggt ata tac ttt atg tac atc ata agg gac      528
 Thr Asn Thr Lys Leu Glu Gly Ile Tyr Phe Met Tyr Ile Ile Arg Asp
                 165                 170                 175

 ctg ctg aag gat gtt cat cac agt att atc tat ggc aat ggg gag cta      576
 Leu Leu Lys Asp Val His His Ser Ile Ile Tyr Gly Asn Gly Glu Leu
             180                 185                 190

 gag ggt ctc ctc aca gac ctt tct acc tac cca aat tct cac cct ccc      624
 Glu Gly Leu Leu Thr Asp Leu Ser Thr Tyr Pro Asn Ser His Pro Pro
         195                 200                 205

 cgt gta caa gaa cct aag gca aat gac gca aaa gta tct act gcc aag      672
 Arg Val Gln Glu Pro Lys Ala Asn Asp Ala Lys Val Ser Thr Ala Lys
     210                 215                 220

 gga aaa gtt ggc caa gtg tcc ctc aga agc cat tta gag caa act gaa      720
 Gly Lys Val Gly Gln Val Ser Leu Arg Ser His Leu Glu Gln Thr Glu
 225                 230                 235                 240

 cct cat act tgc cca cct ctg aaa taa                                  747
 Pro His Thr Cys Pro Pro Leu Lys 
                 245





      <210> 819
      <211> 636
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(636)

      <400> 819
  atg ctg ggg aag ctg att gtc tac ctc tat ctc act ttt tcc agt gca      48
  Met Leu Gly Lys Leu Ile Val Tyr Leu Tyr Leu Thr Phe Ser Ser Ala
    1               5                  10                  15

 gaa acc atg aat cag ggc aaa ctt ttc cat gcc tgt ggt gca ggg cag       96
 Glu Thr Met Asn Gln Gly Lys Leu Phe His Ala Cys Gly Ala Gly Gln
              20                  25                  30

 att gag tgg aag ggc att gtg aat atc gaa atc cta ttc tct tac cat      144
 Ile Glu Trp Lys Gly Ile Val Asn Ile Glu Ile Leu Phe Ser Tyr His
          35                  40                  45

 ctg ctc aga gtt ttt tca ctt ctg tat ggc cat ggg aac tgt ctc atc      192
 Leu Leu Arg Val Phe Ser Leu Leu Tyr Gly His Gly Asn Cys Leu Ile
      50                  55                  60

 ctc ata ttt gag ctc tgg gat agt gct gct gag aaa ctt ggt cct aag      240
 Leu Ile Phe Glu Leu Trp Asp Ser Ala Ala Glu Lys Leu Gly Pro Lys
  65                  70                  75                  80

 acc aac cag ccc aag gaa cat ctc acc aat ttt aaa tca gag gag ggg      288
 Thr Asn Gln Pro Lys Glu His Leu Thr Asn Phe Lys Ser Glu Glu Gly
                  85                  90                  95

 caa gta ccc caa cct cgt atc tct gtg ccc caa tcc ctt att tcc gtg      336
 Gln Val Pro Gln Pro Arg Ile Ser Val Pro Gln Ser Leu Ile Ser Val
             100                 105                 110

 ccc caa cct ctt ata tct ctg cac ccc aat ccc tta ttt cca tgc ccc      384
 Pro Gln Pro Leu Ile Ser Leu His Pro Asn Pro Leu Phe Pro Cys Pro
         115                 120                 125

 gag ccc tta ttt ctg tgc cct gac ccc tta ttt cca tgc acc tac ccc      432
 Glu Pro Leu Phe Leu Cys Pro Asp Pro Leu Phe Pro Cys Thr Tyr Pro
     130                 135                 140

 tta ttt cca tgc ccc aac ccc tta tct ctg tgc ccc atc cct tat ttc      480
 Leu Phe Pro Cys Pro Asn Pro Leu Ser Leu Cys Pro Ile Pro Tyr Phe
 145                 150                 155                 160

 tgt gcc ccg acc tct tat ctc tgc gcc cca acc cct ttt ccc act ttt      528
 Cys Ala Pro Thr Ser Tyr Leu Cys Ala Pro Thr Pro Phe Pro Thr Phe
                 165                 170                 175

 ctg gaa gga gct tgc tac atg tgc cag aaa tct ggc cac tgg gcc aag      576
 Leu Glu Gly Ala Cys Tyr Met Cys Gln Lys Ser Gly His Trp Ala Lys
             180                 185                 190

 gaa tgc ccg cag cgc cgg att cct cct aag ccg cgt ccc atc tat gtg      624
 Glu Cys Pro Gln Arg Arg Ile Pro Pro Lys Pro Arg Pro Ile Tyr Val
         195                 200                 205

 gga ccc cac tga                                                      636
 Gly Pro His 
     210





      <210> 820
      <211> 654
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(654)

      <400> 820
  atg tta cag ccc ttt tac tct cac ctc ctg cag ctg gtg agc agg ggt      48
  Met Leu Gln Pro Phe Tyr Ser His Leu Leu Gln Leu Val Ser Arg Gly
    1               5                  10                  15

 gtt aga gct ctt ttt gct ccc aca gtt cag caa att ccg ggt tct tgt       96
 Val Arg Ala Leu Phe Ala Pro Thr Val Gln Gln Ile Pro Gly Ser Cys
              20                  25                  30

 ccc atg act aag agg aat gaa gtc acg gac acc gga gag cga cat ata      144
 Pro Met Thr Lys Arg Asn Glu Val Thr Asp Thr Gly Glu Arg His Ile
          35                  40                  45

 atg ctt aca gtc agg tca gat tcc ttg ata aca gca ggg aac aaa aat      192
 Met Leu Thr Val Arg Ser Asp Ser Leu Ile Thr Ala Gly Asn Lys Asn
      50                  55                  60

 ggg aag aac agg cag gct ttc cgg ggc agt gtt gat gtg ggg gca ccc      240
 Gly Lys Asn Arg Gln Ala Phe Arg Gly Ser Val Asp Val Gly Ala Pro
  65                  70                  75                  80

 aag cca att gcc att gaa cca tgt gct ggg aac aga gct gct gtt ctg      288
 Lys Pro Ile Ala Ile Glu Pro Cys Ala Gly Asn Arg Ala Ala Val Leu
                  85                  90                  95

 act gtg ttt ctt tgt cta cca cga gga tca tca ggt gcc cct ccc cct      336
 Thr Val Phe Leu Cys Leu Pro Arg Gly Ser Ser Gly Ala Pro Pro Pro
             100                 105                 110

 ggg cag tca ggc att ccc cca ggt ctg atc ctt agc cag ctt ctt tta      384
 Gly Gln Ser Gly Ile Pro Pro Gly Leu Ile Leu Ser Gln Leu Leu Leu
         115                 120                 125

 cct ctc cac tca ctt agg gaa aac ttc tct gca gct aac tgc cga tcc      432
 Pro Leu His Ser Leu Arg Glu Asn Phe Ser Ala Ala Asn Cys Arg Ser
     130                 135                 140

 tgt ggg tct tca gcc aac acc tct cac ctg ctg agc agc agc atc tca      480
 Cys Gly Ser Ser Ala Asn Thr Ser His Leu Leu Ser Ser Ser Ile Ser
 145                 150                 155                 160

 acc tgg att tcc tcc cgt tca gag aaa cac aga gct agg aag ggc act      528
 Thr Trp Ile Ser Ser Arg Ser Glu Lys His Arg Ala Arg Lys Gly Thr
                 165                 170                 175

 gaa atg aca tat ggc tcc tcc aac tgc atg cag cca cag ctg gtg acc      576
 Glu Met Thr Tyr Gly Ser Ser Asn Cys Met Gln Pro Gln Leu Val Thr
             180                 185                 190

 ctg tcc aga atc atc ttg gac aga cag act gtt tct aaa gac att ccc      624
 Leu Ser Arg Ile Ile Leu Asp Arg Gln Thr Val Ser Lys Asp Ile Pro
         195                 200                 205

 aaa agt cat gct gat aac ttc cgg gac taa                              654
 Lys Ser His Ala Asp Asn Phe Arg Asp 
     210                 215





      <210> 821
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 821
  atg ccc cgc cgc gtc ctg ctg ccc atc ctg ccc ggg ttg tcg cgg gcc      48
  Met Pro Arg Arg Val Leu Leu Pro Ile Leu Pro Gly Leu Ser Arg Ala
    1               5                  10                  15

 ggg ggc acg aca aga ggc cgg ggt ctg ccc gga cgc agc ggc ctg cag       96
 Gly Gly Thr Thr Arg Gly Arg Gly Leu Pro Gly Arg Ser Gly Leu Gln
              20                  25                  30

 ggc gca gct gtc cct cca cca gcc ggg att ctc cag tac aag aag agg      144
 Gly Ala Ala Val Pro Pro Pro Ala Gly Ile Leu Gln Tyr Lys Lys Arg
          35                  40                  45

 ttc tcg gag ctg gag cag ctg ttg gag aga tcc gga gag ctg gag cag      192
 Phe Ser Glu Leu Glu Gln Leu Leu Glu Arg Ser Gly Glu Leu Glu Gln
      50                  55                  60

 cag cag ctg agg gac gca gag cac agc caa gac ctg gag att gcc ctc      240
 Gln Gln Leu Arg Asp Ala Glu His Ser Gln Asp Leu Glu Ile Ala Leu
  65                  70                  75                  80

 atc tgg ctg gag gag gag cag cag gga ggg cca ggg ctg gca gca tgg      288
 Ile Trp Leu Glu Glu Glu Gln Gln Gly Gly Pro Gly Leu Ala Ala Trp
                  85                  90                  95

 ccc cct ggg cga gcg cct act gat ccc ctg tgc ccc att cag gag tgc      336
 Pro Pro Gly Arg Ala Pro Thr Asp Pro Leu Cys Pro Ile Gln Glu Cys
             100                 105                 110

 cag cct ggc cca ggt gaa tgc cat gct ctg aga aca gct gga cta ggc      384
 Gln Pro Gly Pro Gly Glu Cys His Ala Leu Arg Thr Ala Gly Leu Gly
         115                 120                 125

 agg ttt ggc caa cca ggc tct gag tga                                  411
 Arg Phe Gly Gln Pro Gly Ser Glu 
     130                 135





      <210> 822
      <211> 1263
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1263)

      <400> 822
  atg cca aac tct ctg agc tgt gca ctg gct gga gtc ctg ctc ctg cca      48
  Met Pro Asn Ser Leu Ser Cys Ala Leu Ala Gly Val Leu Leu Leu Pro
    1               5                  10                  15

 cct ctc ctg gca gct ctc cct gcc agg att atc aat cag tgg aaa gtg       96
 Pro Leu Leu Ala Ala Leu Pro Ala Arg Ile Ile Asn Gln Trp Lys Val
              20                  25                  30

 ata gaa gca atg gat cag cag aat ggg tat aga ggt aag aca gca gtt      144
 Ile Glu Ala Met Asp Gln Gln Asn Gly Tyr Arg Gly Lys Thr Ala Val
          35                  40                  45

 gca gca gca gtg gtg ctt ggc tct gac agt gaa gtc cag gct aag gtg      192
 Ala Ala Ala Val Val Leu Gly Ser Asp Ser Glu Val Gln Ala Lys Val
      50                  55                  60

 gtc tca gat gga aat gag gaa ctt ctt ggg aac tgg agc aaa ggt cac      240
 Val Ser Asp Gly Asn Glu Glu Leu Leu Gly Asn Trp Ser Lys Gly His
  65                  70                  75                  80

 tat tgc tat gct tta gca aag aga ctg tcg gca ttt tgc ccc tgc cct      288
 Tyr Cys Tyr Ala Leu Ala Lys Arg Leu Ser Ala Phe Cys Pro Cys Pro
                  85                  90                  95

 aga gac ctg tgg aac tct gaa tgt gag aga gat gat gtg aaa ttg gaa      336
 Arg Asp Leu Trp Asn Ser Glu Cys Glu Arg Asp Asp Val Lys Leu Glu
             100                 105                 110

 cct atg ttt aaa agg gaa gga gag cat aaa agt ttg gaa aat ttg cag      384
 Pro Met Phe Lys Arg Glu Gly Glu His Lys Ser Leu Glu Asn Leu Gln
         115                 120                 125

 cct gat gat gca ata gaa aag gaa aac cca ttt tct ggg gag acg ttc      432
 Pro Asp Asp Ala Ile Glu Lys Glu Asn Pro Phe Ser Gly Glu Thr Phe
     130                 135                 140

 aag ctg cct gca gaa att tgc ata agt aac aag gag cag aat gtt aat      480
 Lys Leu Pro Ala Glu Ile Cys Ile Ser Asn Lys Glu Gln Asn Val Asn
 145                 150                 155                 160

 tgc caa gac cat ggg gaa aat gtc ccc agg gca tgt cag aga tct tgg      528
 Cys Gln Asp His Gly Glu Asn Val Pro Arg Ala Cys Gln Arg Ser Trp
                 165                 170                 175

 tgg cag ccc ctc cca tca gag gca tgg agg cct agg agg aaa ata tgg      576
 Trp Gln Pro Leu Pro Ser Glu Ala Trp Arg Pro Arg Arg Lys Ile Trp
             180                 185                 190

 ttt cat ggg tcg gcc cgt cac tat gtg cag cct tgg gac ttg gtc ccc      624
 Phe His Gly Ser Ala Arg His Tyr Val Gln Pro Trp Asp Leu Val Pro
         195                 200                 205

 tgc atc tca gcc atg gct aaa agg gac caa ggg ttg gag ccc tca tgg      672
 Cys Ile Ser Ala Met Ala Lys Arg Asp Gln Gly Leu Glu Pro Ser Trp
     210                 215                 220

 aga acc tct gct agg gca atg cag aag gga aat gtg ggg tcg gag ccc      720
 Arg Thr Ser Ala Arg Ala Met Gln Lys Gly Asn Val Gly Ser Glu Pro
 225                 230                 235                 240

 cca cac aga gtc ccc act ggg gca ctg cct agt gga gct gtg aga aga      768
 Pro His Arg Val Pro Thr Gly Ala Leu Pro Ser Gly Ala Val Arg Arg
                 245                 250                 255

 ggg cca cca tcc tcc aga ccc cag aat ggc agc tcc act gac agc ttg      816
 Gly Pro Pro Ser Ser Arg Pro Gln Asn Gly Ser Ser Thr Asp Ser Leu
             260                 265                 270

 cac tgt gtg cct cgg aaa gct gaa gac att caa tgc aag ccc atg aaa      864
 His Cys Val Pro Arg Lys Ala Glu Asp Ile Gln Cys Lys Pro Met Lys
         275                 280                 285

 gca gag agg ggg act gta ccc tgc gaa gcc aca ggg gtg gct gcc caa      912
 Ala Glu Arg Gly Thr Val Pro Cys Glu Ala Thr Gly Val Ala Ala Gln
     290                 295                 300

 ggc tat ggg agc cca cct ctt gca tca gtg tgc ctt aga tcc ctc aac      960
 Gly Tyr Gly Ser Pro Pro Leu Ala Ser Val Cys Leu Arg Ser Leu Asn
 305                 310                 315                 320

 ggg gct gca gga agc cat tac caa tat cag att ggg cag gca atg ttc     1008
 Gly Ala Ala Gly Ser His Tyr Gln Tyr Gln Ile Gly Gln Ala Met Phe
                 325                 330                 335

 agt ctt tgt atg gtg gaa agt gga gct gat gag gtt aat ttg cac ggt     1056
 Ser Leu Cys Met Val Glu Ser Gly Ala Asp Glu Val Asn Leu His Gly
             340                 345                 350

 gtg acc agc ctt ggc tta aag cag gct ctg gag ttt gca tac aca gga     1104
 Val Thr Ser Leu Gly Leu Lys Gln Ala Leu Glu Phe Ala Tyr Thr Gly
         355                 360                 365

 cag ctg gca gta cct acc tgg caa gta aaa ggc cct gag gca cct cca     1152
 Gln Leu Ala Val Pro Thr Trp Gln Val Lys Gly Pro Glu Ala Pro Pro
     370                 375                 380

 ctg tgc ctt gca ctc tgg agg gta cac agt gaa atc cac att tta agg     1200
 Leu Cys Leu Ala Leu Trp Arg Val His Ser Glu Ile His Ile Leu Arg
 385                 390                 395                 400

 aag aat ata gca tcc ctt cct tac ctg ctg ggg cta tat tcc aag acc     1248
 Lys Asn Ile Ala Ser Leu Pro Tyr Leu Leu Gly Leu Tyr Ser Lys Thr
                 405                 410                 415

 cca gtg gat gcc tga                                                 1263
 Pro Val Asp Ala 
             420





      <210> 823
      <211> 1461
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1461)

      <400> 823
  atg gct ttt gga gtc aga tgt acc tgg gtt caa att gtg gtt ctg ctg      48
  Met Ala Phe Gly Val Arg Cys Thr Trp Val Gln Ile Val Val Leu Leu
    1               5                  10                  15

 ctc att agc tct ggg acc ctg gat gat tac ttt cct tac gcc gcc cca       96
 Leu Ile Ser Ser Gly Thr Leu Asp Asp Tyr Phe Pro Tyr Ala Ala Pro
              20                  25                  30

 cct ccc caa gaa ccc gtg aag act ctg aga agc ctg gtc aat atc cga      144
 Pro Pro Gln Glu Pro Val Lys Thr Leu Arg Ser Leu Val Asn Ile Arg
          35                  40                  45

 aag gac aca ctg agg ctc gtc aaa tgt gct gag gaa gtg aag agc cct      192
 Lys Asp Thr Leu Arg Leu Val Lys Cys Ala Glu Glu Val Lys Ser Pro
      50                  55                  60

 gga gaa gag gcc agt aaa gct aaa gtc cac tac aat gtt gag ttc acc      240
 Gly Glu Glu Ala Ser Lys Ala Lys Val His Tyr Asn Val Glu Phe Thr
  65                  70                  75                  80

 ttt gac aca gat gct cgg gta gcc atc acc atc tat tac cag gcc acg      288
 Phe Asp Thr Asp Ala Arg Val Ala Ile Thr Ile Tyr Tyr Gln Ala Thr
                  85                  90                  95

 gaa gag ttc cag aat ggt att gcc agc tac att ccc aaa gac aac agc      336
 Glu Glu Phe Gln Asn Gly Ile Ala Ser Tyr Ile Pro Lys Asp Asn Ser
             100                 105                 110

 ctc cag tcg gag act gtg cag tac aag cga gga gtg tgt cag cag ttc      384
 Leu Gln Ser Glu Thr Val Gln Tyr Lys Arg Gly Val Cys Gln Gln Phe
         115                 120                 125

 tgc ctg ccc tcc cac acc gtg gat ccc tcc gag tgg gcc gaa gag gag      432
 Cys Leu Pro Ser His Thr Val Asp Pro Ser Glu Trp Ala Glu Glu Glu
     130                 135                 140

 ctt ggc ttt gat tta gac cga gaa gtt tac cct cta gtg gta cat gcc      480
 Leu Gly Phe Asp Leu Asp Arg Glu Val Tyr Pro Leu Val Val His Ala
 145                 150                 155                 160

 gtg gtg gat gaa gga gac gag tat ttt ggc cat tgc cat gta ctg ctg      528
 Val Val Asp Glu Gly Asp Glu Tyr Phe Gly His Cys His Val Leu Leu
                 165                 170                 175

 ggt act ttt gag aag gta gac ggg gtc agc tac ctc ctt cag gag atc      576
 Gly Thr Phe Glu Lys Val Asp Gly Val Ser Tyr Leu Leu Gln Glu Ile
             180                 185                 190

 tat gga att gaa aac aag tac aac aca caa gat tct aag gtg gct gaa      624
 Tyr Gly Ile Glu Asn Lys Tyr Asn Thr Gln Asp Ser Lys Val Ala Glu
         195                 200                 205

 gac gaa gtg agt gat aac agt gcc gag tgt gtg gtg tgt ctc tcg gat      672
 Asp Glu Val Ser Asp Asn Ser Ala Glu Cys Val Val Cys Leu Ser Asp
     210                 215                 220

 gtc cgg gac acc ttg att ctg ccc tgt cgc cac ctc tgc ctc tgt aac      720
 Val Arg Asp Thr Leu Ile Leu Pro Cys Arg His Leu Cys Leu Cys Asn
 225                 230                 235                 240

 acc tgt gca gac acg ctg cgc tac cag gcc aac aac tgc ccc atc tgc      768
 Thr Cys Ala Asp Thr Leu Arg Tyr Gln Ala Asn Asn Cys Pro Ile Cys
                 245                 250                 255

 cga ctg cgt aag ccc cag agc ggc agg ggg act gcc ttc cgg gca ctg      816
 Arg Leu Arg Lys Pro Gln Ser Gly Arg Gly Thr Ala Phe Arg Ala Leu
             260                 265                 270

 ctt cag atc cga gcc atg agg aaa aaa ttg ggc ccc ttg tcc cca acc      864
 Leu Gln Ile Arg Ala Met Arg Lys Lys Leu Gly Pro Leu Ser Pro Thr
         275                 280                 285

 agc ttt aac ccc atc atc tca tcc cag aca tct gac tct gaa gag cat      912
 Ser Phe Asn Pro Ile Ile Ser Ser Gln Thr Ser Asp Ser Glu Glu His
     290                 295                 300

 cca tcc tca gag aat att cca cca ggc tat gaa gta gta tct ctt ctg      960
 Pro Ser Ser Glu Asn Ile Pro Pro Gly Tyr Glu Val Val Ser Leu Leu
 305                 310                 315                 320

 gag gcc ctc aac ggg ccc ctc acc ccg tcc cca gca gtt cct cca ctt     1008
 Glu Ala Leu Asn Gly Pro Leu Thr Pro Ser Pro Ala Val Pro Pro Leu
                 325                 330                 335

 cac gtg ctt gga gat ggc cac ctc tca gga atg ctc cct tca tat ggc     1056
 His Val Leu Gly Asp Gly His Leu Ser Gly Met Leu Pro Ser Tyr Gly
             340                 345                 350

 agt gat ggc cac ctg ccc ccc gtc agg acg atc tcg cct ctt gac cgc     1104
 Ser Asp Gly His Leu Pro Pro Val Arg Thr Ile Ser Pro Leu Asp Arg
         355                 360                 365

 ctg tct gac agc agc agt cag gga ctc aaa ctc aaa aag agt ctc tcc     1152
 Leu Ser Asp Ser Ser Ser Gln Gly Leu Lys Leu Lys Lys Ser Leu Ser
     370                 375                 380

 aaa tcc act tcc caa aac tct tcc gtg ctg cat gaa gag gaa gat gag     1200
 Lys Ser Thr Ser Gln Asn Ser Ser Val Leu His Glu Glu Glu Asp Glu
 385                 390                 395                 400

 cat tcc tgc agc gag tcg gag aca cag ctc tct cag aga ccg tcg gtt     1248
 His Ser Cys Ser Glu Ser Glu Thr Gln Leu Ser Gln Arg Pro Ser Val
                 405                 410                 415

 cag cat ctc gga gag atc agc act gac acc gtc tcc tcc atg tct ggc     1296
 Gln His Leu Gly Glu Ile Ser Thr Asp Thr Val Ser Ser Met Ser Gly
             420                 425                 430

 tcc tac atc gcc cct ggc act gaa gag gag gga gag gct ctc tct tcc     1344
 Ser Tyr Ile Ala Pro Gly Thr Glu Glu Glu Gly Glu Ala Leu Ser Ser
         435                 440                 445

 ccc cag cct gcc agc agg gcc ccc tca gaa gaa gga gag ggg cac ctc     1392
 Pro Gln Pro Ala Ser Arg Ala Pro Ser Glu Glu Gly Glu Gly His Leu
     450                 455                 460

 cag agc aca cgt atg ccc ggc ctg gat aca gac gca cca gca gat gtc     1440
 Gln Ser Thr Arg Met Pro Gly Leu Asp Thr Asp Ala Pro Ala Asp Val
 465                 470                 475                 480

 atc ctg ttg ctt ctg ctt tag                                         1461
 Ile Leu Leu Leu Leu Leu 
                 485





      <210> 824
      <211> 966
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(966)

      <400> 824
  atg gag tgg gaa ctc aac ttg ctg ctc tac ctg gcg ctc ttc ttc ttc      48
  Met Glu Trp Glu Leu Asn Leu Leu Leu Tyr Leu Ala Leu Phe Phe Phe
    1               5                  10                  15

 ctg ctc ttc tta ctt ttc ctc ctg ctc ttc gtg gtc atc aag cag ctg       96
 Leu Leu Phe Leu Leu Phe Leu Leu Leu Phe Val Val Ile Lys Gln Leu
              20                  25                  30

 aag aac tcc gtg gcc aac acg gcc ggg gcg ctc cag ccc ggg cgc tct      144
 Lys Asn Ser Val Ala Asn Thr Ala Gly Ala Leu Gln Pro Gly Arg Ser
          35                  40                  45

 cgg tgc acc gcg agc ctt ggg gct tct ccc gag agc aag cgg tgt gac      192
 Arg Cys Thr Ala Ser Leu Gly Ala Ser Pro Glu Ser Lys Arg Cys Asp
      50                  55                  60

 ccg agt gcg ggc act ggc ggg agg gca cct gag ctg cgc ggc gct ggg      240
 Pro Ser Ala Gly Thr Gly Gly Arg Ala Pro Glu Leu Arg Gly Ala Gly
  65                  70                  75                  80

 ctg ggt ctc cgc ctc gat tct ccg tcc tcg cgg cct ccc agc ttc cag      288
 Leu Gly Leu Arg Leu Asp Ser Pro Ser Ser Arg Pro Pro Ser Phe Gln
                  85                  90                  95

 gtg cgg ggc tcg gcg gct ctg acg ggt ccg ttc cgg cgt gag gcg cag      336
 Val Arg Gly Ser Ala Ala Leu Thr Gly Pro Phe Arg Arg Glu Ala Gln
             100                 105                 110

 gga ccc gcg tct ccg ctc ctg tgg gag gcc cgg ggc tcg cag cgc gtt      384
 Gly Pro Ala Ser Pro Leu Leu Trp Glu Ala Arg Gly Ser Gln Arg Val
         115                 120                 125

 cgg gtg cca ggg acg cca cca acc acg gtt agt gct tgc gga ttg ccg      432
 Arg Val Pro Gly Thr Pro Pro Thr Thr Val Ser Ala Cys Gly Leu Pro
     130                 135                 140

 tgc agg gta ggt ttc gaa tct ggg aca gcg gat ggt gaa cgt tac agt      480
 Cys Arg Val Gly Phe Glu Ser Gly Thr Ala Asp Gly Glu Arg Tyr Ser
 145                 150                 155                 160

 gag agt cat ttg gaa gat gcc tta ggg ttg gcc gcc gag ctg ctg ccc      528
 Glu Ser His Leu Glu Asp Ala Leu Gly Leu Ala Ala Glu Leu Leu Pro
                 165                 170                 175

 ttg act ggt gct cag ggg acc aca gct gca atg aca gtt tgg gcc tgc      576
 Leu Thr Gly Ala Gln Gly Thr Thr Ala Ala Met Thr Val Trp Ala Cys
             180                 185                 190

 aaa aag aag gct gga aca acg gga gat gga agc ttt ctg caa atg gtg      624
 Lys Lys Lys Ala Gly Thr Thr Gly Asp Gly Ser Phe Leu Gln Met Val
         195                 200                 205

 ttc aaa atg gct tca gat ctt atc agg aca atc ttg gct gtt gca cta      672
 Phe Lys Met Ala Ser Asp Leu Ile Arg Thr Ile Leu Ala Val Ala Leu
     210                 215                 220

 att tcc aaa ctt gtt cca aga tgg tcc ccg cag cac ccc aca aga aga      720
 Ile Ser Lys Leu Val Pro Arg Trp Ser Pro Gln His Pro Thr Arg Arg
 225                 230                 235                 240

 agg agg aag ccc aca gag aaa acg ggg cat gcc agt tca aat cca ctt      768
 Arg Arg Lys Pro Thr Glu Lys Thr Gly His Ala Ser Ser Asn Pro Leu
                 245                 250                 255

 cct ttt aaa gag ctt cct cag cag ccc aat aac ttt tgc ctt cat ctc      816
 Pro Phe Lys Glu Leu Pro Gln Gln Pro Asn Asn Phe Cys Leu His Leu
             260                 265                 270

 att ggc cag aac tgt gtc att ggc tac tgc tat ctg caa gat tgt ctg      864
 Ile Gly Gln Asn Cys Val Ile Gly Tyr Cys Tyr Leu Gln Asp Cys Leu
         275                 280                 285

 aga aat gta gtt ttt gta gct gga tat ata act gcc ttt gac aaa aat      912
 Arg Asn Val Val Phe Val Ala Gly Tyr Ile Thr Ala Phe Asp Lys Asn
     290                 295                 300

 cca gtt tct ctt gat gaa gaa gaa gat gat ggt gga tct tgg gag gac      960
 Pro Val Ser Leu Asp Glu Glu Glu Asp Asp Gly Gly Ser Trp Glu Asp
 305                 310                 315                 320

 aac taa                                                              966
 Asn 






      <210> 825
      <211> 270
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(270)

      <400> 825
  atg agc ttg aag ggc cag gga gga caa agc ccc atc gtc ctc atc cta      48
  Met Ser Leu Lys Gly Gln Gly Gly Gln Ser Pro Ile Val Leu Ile Leu
    1               5                  10                  15

 aat cgg aag tca gtg gcc ttc tcc atg cta tgg ctg ctg tct atg tct       96
 Asn Arg Lys Ser Val Ala Phe Ser Met Leu Trp Leu Leu Ser Met Ser
              20                  25                  30

 gct cag cct ggc ccc ctg ccc cag tca aac acc cct gtg gcc ata gct      144
 Ala Gln Pro Gly Pro Leu Pro Gln Ser Asn Thr Pro Val Ala Ile Ala
          35                  40                  45

 cct ggg ctc cca gtg tgc cat ggg gaa agc act tcc tca tcc gga atc      192
 Pro Gly Leu Pro Val Cys His Gly Glu Ser Thr Ser Ser Ser Gly Ile
      50                  55                  60

 gct cgt tac tcg tgc tac atg aag aac tca gac atc aca gag ggg gca      240
 Ala Arg Tyr Ser Cys Tyr Met Lys Asn Ser Asp Ile Thr Glu Gly Ala
  65                  70                  75                  80

 gtc gcc agg aag cag agc tct gga ctg tga                              270
 Val Ala Arg Lys Gln Ser Ser Gly Leu 
                  85





      <210> 826
      <211> 195
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(195)

      <400> 826
  atg gtc ctg gtg ctg cac cac atc ctc atc gct gtt gtc caa ttc ctc      48
  Met Val Leu Val Leu His His Ile Leu Ile Ala Val Val Gln Phe Leu
    1               5                  10                  15

 agg cgg ggc cag cag gtc ttc ctc aag ccg gac gag ccg ccg ccg ccg       96
 Arg Arg Gly Gln Gln Val Phe Leu Lys Pro Asp Glu Pro Pro Pro Pro
              20                  25                  30

 ccg cag cca tgc gcc gac agc ctg cag gga gga gac ccc tcc tct agt      144
 Pro Gln Pro Cys Ala Asp Ser Leu Gln Gly Gly Asp Pro Ser Ser Ser
          35                  40                  45

 tct gaa ttc tac tcc tgt gct ggg acg gca gcg cag acc aag agc cct      192
 Ser Glu Phe Tyr Ser Cys Ala Gly Thr Ala Ala Gln Thr Lys Ser Pro
      50                  55                  60

 tga                                                                  195
 






      <210> 827
      <211> 741
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(741)

      <400> 827
  atg tgg cgc ctg gtg ccc ccg aag ctg ggc cgc ctg tcc cgc tcg ctg      48
  Met Trp Arg Leu Val Pro Pro Lys Leu Gly Arg Leu Ser Arg Ser Leu
    1               5                  10                  15

 aag ctg gcg gcg ctg ggc agc ctg ttg gtg ctg atg gtg ctg cac tcg       96
 Lys Leu Ala Ala Leu Gly Ser Leu Leu Val Leu Met Val Leu His Ser
              20                  25                  30

 ccg tcg ctg ctc gcc tct tgg cag cgc aac gaa ctg acc gac cgg cgc      144
 Pro Ser Leu Leu Ala Ser Trp Gln Arg Asn Glu Leu Thr Asp Arg Arg
          35                  40                  45

 ttc ctg cag ctc aat aag tgc ccg gcg tgc ttc ggc acg agc tgg tgc      192
 Phe Leu Gln Leu Asn Lys Cys Pro Ala Cys Phe Gly Thr Ser Trp Cys
      50                  55                  60

 cgc cgc ttc ctc aac ggg cag gtg gta ttc gag gcg tgg ggc cgc ttg      240
 Arg Arg Phe Leu Asn Gly Gln Val Val Phe Glu Ala Trp Gly Arg Leu
  65                  70                  75                  80

 cgc ctg ctg gac ttc ctc aac gtg aag aac gtg tac ttc gcg cag tac      288
 Arg Leu Leu Asp Phe Leu Asn Val Lys Asn Val Tyr Phe Ala Gln Tyr
                  85                  90                  95

 ggc gag ccc cgc gag ggc ggc cgc cgc cga gtg gtg ctc aag cgc ctc      336
 Gly Glu Pro Arg Glu Gly Gly Arg Arg Arg Val Val Leu Lys Arg Leu
             100                 105                 110

 ggc tcg cag cgc gag ctg gcg cag ctc gac cag agc atc tgc aag cgg      384
 Gly Ser Gln Arg Glu Leu Ala Gln Leu Asp Gln Ser Ile Cys Lys Arg
         115                 120                 125

 gcc acc ggc cgg ccc cgc tgc gac ctg ctg cag gcc atg ccc cgg acc      432
 Ala Thr Gly Arg Pro Arg Cys Asp Leu Leu Gln Ala Met Pro Arg Thr
     130                 135                 140

 gag ttc gcg cgc ctc aac ggc gac gtg cgt ctg ctc acg ccc gag gcg      480
 Glu Phe Ala Arg Leu Asn Gly Asp Val Arg Leu Leu Thr Pro Glu Ala
 145                 150                 155                 160

 gtg gag ggc tgg tcg gac ctg gtg cac tgc ccc tcg cag cgc ctt ctc      528
 Val Glu Gly Trp Ser Asp Leu Val His Cys Pro Ser Gln Arg Leu Leu
                 165                 170                 175

 gac cgc ctg gtg cgc cgc tac gcg gag acc aag gac tcg ggc agc ttc      576
 Asp Arg Leu Val Arg Arg Tyr Ala Glu Thr Lys Asp Ser Gly Ser Phe
             180                 185                 190

 ctg ctt cgc aac ctc aag gac tcg gag cgc atg cag ctg ctg ctg acc      624
 Leu Leu Arg Asn Leu Lys Asp Ser Glu Arg Met Gln Leu Leu Leu Thr
         195                 200                 205

 ctg gcc ttc aac ccc gag ccg ctg gtg cta cag tca ttt gga cac cta      672
 Leu Ala Phe Asn Pro Glu Pro Leu Val Leu Gln Ser Phe Gly His Leu
     210                 215                 220

 att cga gga caa gtt ggg gag gat gaa gtc gga gaa cgg gac agt ggt      720
 Ile Arg Gly Gln Val Gly Glu Asp Glu Val Gly Glu Arg Asp Ser Gly
 225                 230                 235                 240

 cgg ggt ggg ttt aat ctg tga                                          741
 Arg Gly Gly Phe Asn Leu 
                 245





      <210> 828
      <211> 153
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(153)

      <400> 828
  atg tgg aac ttc atc ctc tca gct ctt aat ctg ggt gtc tgg tta cca      48
  Met Trp Asn Phe Ile Leu Ser Ala Leu Asn Leu Gly Val Trp Leu Pro
    1               5                  10                  15

 gtt cag aag ccg aat aac gag ata ggt ttc ctt cgt cag tcc agg cag       96
 Val Gln Lys Pro Asn Asn Glu Ile Gly Phe Leu Arg Gln Ser Arg Gln
              20                  25                  30

 gac tgt gcg gtt gga aaa ggg acg gat gct ggt cct gga agg ggc gtc      144
 Asp Cys Ala Val Gly Lys Gly Thr Asp Ala Gly Pro Gly Arg Gly Val
          35                  40                  45

 gtt atc tag                                                          153
 Val Ile 
      50





      <210> 829
      <211> 1170
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1170)

      <400> 829
  atg ctg agc ctc gca gcc aag ctg gtg gcc ttc ttc tgg agg acg gcg      48
  Met Leu Ser Leu Ala Ala Lys Leu Val Ala Phe Phe Trp Arg Thr Ala
    1               5                  10                  15

 gac acc cct agg gag gaa gcc ggg cag ctg gag ccc gag ctc gcg gaa       96
 Asp Thr Pro Arg Glu Glu Ala Gly Gln Leu Glu Pro Glu Leu Ala Glu
              20                  25                  30

 ggt gac act aag ctg aaa act gta cgg ggt gtc gtg aca agg tac tgc      144
 Gly Asp Thr Lys Leu Lys Thr Val Arg Gly Val Val Thr Arg Tyr Cys
          35                  40                  45

 agc gat tat ggc atg att gat gat atg atc tac ttc tcc agt gat gct      192
 Ser Asp Tyr Gly Met Ile Asp Asp Met Ile Tyr Phe Ser Ser Asp Ala
      50                  55                  60

 gtg act agc aga gtg ctt ctg aat gtt gga cag gaa gtg att gca gtt      240
 Val Thr Ser Arg Val Leu Leu Asn Val Gly Gln Glu Val Ile Ala Val
  65                  70                  75                  80

 gtg gaa gaa aat aaa gtg tcc aat gga ctg aaa gca atc agg gta gaa      288
 Val Glu Glu Asn Lys Val Ser Asn Gly Leu Lys Ala Ile Arg Val Glu
                  85                  90                  95

 gct gtc tct gat aag tgg gaa gac gac agc aga aac cat ggg agt ccc      336
 Ala Val Ser Asp Lys Trp Glu Asp Asp Ser Arg Asn His Gly Ser Pro
             100                 105                 110

 tca gac tgc ggc ccc cga gtg ttg att ggc tgt gtg act tcc ctg gtg      384
 Ser Asp Cys Gly Pro Arg Val Leu Ile Gly Cys Val Thr Ser Leu Val
         115                 120                 125

 gag ggc gca ggc tgt atc agt cag acc acc tac ttc tct ctg gag agt      432
 Glu Gly Ala Gly Cys Ile Ser Gln Thr Thr Tyr Phe Ser Leu Glu Ser
     130                 135                 140

 gtg tgc gaa ggc ttc gag ccc tgc aag gga gac tgg gtg gag gct gag      480
 Val Cys Glu Gly Phe Glu Pro Cys Lys Gly Asp Trp Val Glu Ala Glu
 145                 150                 155                 160

 tac cgg atc cgg cct ggc acg tgg agc agc gaa gcc acc tca gtg aag      528
 Tyr Arg Ile Arg Pro Gly Thr Trp Ser Ser Glu Ala Thr Ser Val Lys
                 165                 170                 175

 cca ctg aga tac aag cgc gtg gac aag gtc tgc atc tct agc ctc tgt      576
 Pro Leu Arg Tyr Lys Arg Val Asp Lys Val Cys Ile Ser Ser Leu Cys
             180                 185                 190

 gga agg aac ggg gtg tta gag gaa agc atc ttc ttt acc ttg gac tcc      624
 Gly Arg Asn Gly Val Leu Glu Glu Ser Ile Phe Phe Thr Leu Asp Ser
         195                 200                 205

 ttg aaa ctg cca gat ggg tac aca ccc cgg aga ggt gac gtg gtc aat      672
 Leu Lys Leu Pro Asp Gly Tyr Thr Pro Arg Arg Gly Asp Val Val Asn
     210                 215                 220

 gca gtg gtg gtg gag agc agc cag tca tgc tat gtc tgg agg gca ctt      720
 Ala Val Val Val Glu Ser Ser Gln Ser Cys Tyr Val Trp Arg Ala Leu
 225                 230                 235                 240

 tgt atg acc cta gtg aag agg cga gac gcc gcc cct gtt cat gag gcc      768
 Cys Met Thr Leu Val Lys Arg Arg Asp Ala Ala Pro Val His Glu Ala
                 245                 250                 255

 act cat ttc tat gga acg att ttg ctg aag aac aaa ggt gat att gaa      816
 Thr His Phe Tyr Gly Thr Ile Leu Leu Lys Asn Lys Gly Asp Ile Glu
             260                 265                 270

 gtt aca cag ctt ctg aac atg tca aat tac aag gag aag ttt tcg act      864
 Val Thr Gln Leu Leu Asn Met Ser Asn Tyr Lys Glu Lys Phe Ser Thr
         275                 280                 285

 ttg ctg tgg ctt gag gag att tat gca gaa atg gaa ctg aaa gag tat      912
 Leu Leu Trp Leu Glu Glu Ile Tyr Ala Glu Met Glu Leu Lys Glu Tyr
     290                 295                 300

 aac atg agc ggg atc atc tta aga agg aat ggg gat ctg ctg gtt ctg      960
 Asn Met Ser Gly Ile Ile Leu Arg Arg Asn Gly Asp Leu Leu Val Leu
 305                 310                 315                 320

 gag gtc cca ggg ttg gcc gaa ggg agg cct tct ctc tac gca ggt gat     1008
 Glu Val Pro Gly Leu Ala Glu Gly Arg Pro Ser Leu Tyr Ala Gly Asp
                 325                 330                 335

 aaa ctg att tta aaa act caa gag tac aat gga cat gcc atc gaa tac     1056
 Lys Leu Ile Leu Lys Thr Gln Glu Tyr Asn Gly His Ala Ile Glu Tyr
             340                 345                 350

 atc agc tac gtg act gag att cat gaa gaa gat gta act ctt aaa att     1104
 Ile Ser Tyr Val Thr Glu Ile His Glu Glu Asp Val Thr Leu Lys Ile
         355                 360                 365

 aat cca gaa ttt gaa caa gcc tat aac ttt gaa cct atg gat gtg gaa     1152
 Asn Pro Glu Phe Glu Gln Ala Tyr Asn Phe Glu Pro Met Asp Val Glu
     370                 375                 380

 ttt aca tat aat agg taa                                             1170
 Phe Thr Tyr Asn Arg 
 385





      <210> 830
      <211> 291
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(291)

      <400> 830
  atg agc ttg gtg cct ctc ctg gct tct ttt cct gca gga gct gtc ctg      48
  Met Ser Leu Val Pro Leu Leu Ala Ser Phe Pro Ala Gly Ala Val Leu
    1               5                  10                  15

 cac cag tgg aca gaa cgg cgg ctg gtg aac cac aag cag tac ctg gag       96
 His Gln Trp Thr Glu Arg Arg Leu Val Asn His Lys Gln Tyr Leu Glu
              20                  25                  30

 gcc aag agg ctg ttg aag gag ttc cag gca cgt tac cgg cag ctg gtg      144
 Ala Lys Arg Leu Leu Lys Glu Phe Gln Ala Arg Tyr Arg Gln Leu Val
          35                  40                  45

 agt ggc tct ctg cgc aca gtg ttc ggg act acc ccg ctc ccc atg gcc      192
 Ser Gly Ser Leu Arg Thr Val Phe Gly Thr Thr Pro Leu Pro Met Ala
      50                  55                  60

 tgc cca gcg ctg agt gag agc cag ccc aaa ata ggc cac ttc ctc gag      240
 Cys Pro Ala Leu Ser Glu Ser Gln Pro Lys Ile Gly His Phe Leu Glu
  65                  70                  75                  80

 atc aag gat gag ttc tgc cag gag ccc aca gcc agt gac tca caa ggc      288
 Ile Lys Asp Glu Phe Cys Gln Glu Pro Thr Ala Ser Asp Ser Gln Gly
                  85                  90                  95

 tag                                                                  291
 






      <210> 831
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 831
  atg acg ggc atc ttg aga aac agc ctc tgc aga ttc agg gcc ttg tgt      48
  Met Thr Gly Ile Leu Arg Asn Ser Leu Cys Arg Phe Arg Ala Leu Cys
    1               5                  10                  15

 aaa tgt gcc ctg gag gtg cca ccc agt cac aga agg cag tac aca aac       96
 Lys Cys Ala Leu Glu Val Pro Pro Ser His Arg Arg Gln Tyr Thr Asn
              20                  25                  30

 aca gaa ccc tgt ctc ccg act gcc atc tcc atg ggc cat ttg gag gcc      144
 Thr Glu Pro Cys Leu Pro Thr Ala Ile Ser Met Gly His Leu Glu Ala
          35                  40                  45

 agg gag ctg cct cct gta tct tta cag ggg tca ggc cct cct agg gat      192
 Arg Glu Leu Pro Pro Val Ser Leu Gln Gly Ser Gly Pro Pro Arg Asp
      50                  55                  60

 gtg ggg cca gag gga aga ttt gag cat gtg ggg cag agt gac tcc atg      240
 Val Gly Pro Glu Gly Arg Phe Glu His Val Gly Gln Ser Asp Ser Met
  65                  70                  75                  80

 agg acg tca agc aac ccc gcc atg gct ctg ggc ttc tcg cct tgg gtt      288
 Arg Thr Ser Ser Asn Pro Ala Met Ala Leu Gly Phe Ser Pro Trp Val
                  85                  90                  95

 ttc tca tgg aga cat cca tct gtt aaa gat ctt gct tat ggg gca gac      336
 Phe Ser Trp Arg His Pro Ser Val Lys Asp Leu Ala Tyr Gly Ala Asp
             100                 105                 110

 ctg ggg ttt gat gga gag aga ctt gct gga gac aga gcc att cac gca      384
 Leu Gly Phe Asp Gly Glu Arg Leu Ala Gly Asp Arg Ala Ile His Ala
         115                 120                 125

 cac cgc ggc taa                                                      396
 His Arg Gly 
     130





      <210> 832
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 832
  atg ctg tcc tgc cgc ctc cag tgc gcg ctg gct gcg ctg tcc atc gtc      48
  Met Leu Ser Cys Arg Leu Gln Cys Ala Leu Ala Ala Leu Ser Ile Val
    1               5                  10                  15

 ctg gcc ctg ggc tgt gtc acc ggc gct ccc tcg gac ccc aga ctc cgt       96
 Leu Ala Leu Gly Cys Val Thr Gly Ala Pro Ser Asp Pro Arg Leu Arg
              20                  25                  30

 cag ttt ctg cag aag tcc ctg gct gct gcc gcg ggg aag cag agt ttt      144
 Gln Phe Leu Gln Lys Ser Leu Ala Ala Ala Ala Gly Lys Gln Ser Phe
          35                  40                  45

 ggt gct ttt ctg ggt ccc tca gct ccc gaa gct ctt gag aaa act atc      192
 Gly Ala Phe Leu Gly Pro Ser Ala Pro Glu Ala Leu Glu Lys Thr Ile
      50                  55                  60

 aaa ggc tag                                                          201
 Lys Gly 
  65





      <210> 833
      <211> 174
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(174)

      <400> 833
  atg act tac cag cat tca aac cag gct ctg gca ggt gct ttg caa gca      48
  Met Thr Tyr Gln His Ser Asn Gln Ala Leu Ala Gly Ala Leu Gln Ala
    1               5                  10                  15

 ctt atg ttc aag gct atc tgg gta tta atc ctg att cag ctg tcc aaa       96
 Leu Met Phe Lys Ala Ile Trp Val Leu Ile Leu Ile Gln Leu Ser Lys
              20                  25                  30

 gaa gat aag cat gaa att atc ctt cca aca tct att aag caa gca aga      144
 Glu Asp Lys His Glu Ile Ile Leu Pro Thr Ser Ile Lys Gln Ala Arg
          35                  40                  45

 ctt aat cat gcc aaa acc aac ctt tac taa                              174
 Leu Asn His Ala Lys Thr Asn Leu Tyr 
      50                  55





      <210> 834
      <211> 471
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(471)

      <400> 834
  atg cag acc aga cga att ccg agt gtg tgg ctt ggt act tgg atg tgt      48
  Met Gln Thr Arg Arg Ile Pro Ser Val Trp Leu Gly Thr Trp Met Cys
    1               5                  10                  15

 gac aat gtg ctc ctg ttc acc gtc tct gca gtt tca ccc aca gag cga       96
 Asp Asn Val Leu Leu Phe Thr Val Ser Ala Val Ser Pro Thr Glu Arg
              20                  25                  30

 acc tcg gtc cgc agt cct cag agc gtg cag ccc acg agc aca gct gct      144
 Thr Ser Val Arg Ser Pro Gln Ser Val Gln Pro Thr Ser Thr Ala Ala
          35                  40                  45

 ccg acg cat gca gtg ctc cct ggc cag ctc atc ctc act ctg aag tcg      192
 Pro Thr His Ala Val Leu Pro Gly Gln Leu Ile Leu Thr Leu Lys Ser
      50                  55                  60

 ggc att gtc cat cca gac aat ctg cac aac cac cag gtg agg acg gaa      240
 Gly Ile Val His Pro Asp Asn Leu His Asn His Gln Val Arg Thr Glu
  65                  70                  75                  80

 ttt cgt ttg aat ccc tac tgc tta gat acg gag act gag gct gac aag      288
 Phe Arg Leu Asn Pro Tyr Cys Leu Asp Thr Glu Thr Glu Ala Asp Lys
                  85                  90                  95

 gat tgt gtg gcc agc cca gtg tca ctc agc tgt tca aat ctg ggg aaa      336
 Asp Cys Val Ala Ser Pro Val Ser Leu Ser Cys Ser Asn Leu Gly Lys
             100                 105                 110

 gaa cat tcc atg gag aag gaa cag gac att cac tgc cct gcg tgt ggc      384
 Glu His Ser Met Glu Lys Glu Gln Asp Ile His Cys Pro Ala Cys Gly
         115                 120                 125

 atg ttc agt gga agg aaa gga aag gaa gaa gag aga gag aag aga aga      432
 Met Phe Ser Gly Arg Lys Gly Lys Glu Glu Glu Arg Glu Lys Arg Arg
     130                 135                 140

 gag aag gaa gat gag aat gct gag tct cag att aag taa                  471
 Glu Lys Glu Asp Glu Asn Ala Glu Ser Gln Ile Lys 
 145                 150                 155





      <210> 835
      <211> 741
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(741)

      <400> 835
  atg gcc cgc ggg gct gcg ctg gcg ctg ctg ctc ttc ggc ctg ctg ggt      48
  Met Ala Arg Gly Ala Ala Leu Ala Leu Leu Leu Phe Gly Leu Leu Gly
    1               5                  10                  15

 gtt ctg gtc gcc gcc ccg ggt gag cga gcg gag gga tcc ggg tat cca       96
 Val Leu Val Ala Ala Pro Gly Glu Arg Ala Glu Gly Ser Gly Tyr Pro
              20                  25                  30

 tgt gtc ctt cca tcc att tat cca tcc att tat gca tcc atg cat cca      144
 Cys Val Leu Pro Ser Ile Tyr Pro Ser Ile Tyr Ala Ser Met His Pro
          35                  40                  45

 tcc agc cat gca tcc tcc ttt tat cca tcc atc cat caa ccc atc ctc      192
 Ser Ser His Ala Ser Ser Phe Tyr Pro Ser Ile His Gln Pro Ile Leu
      50                  55                  60

 cca ttc att tac cca tcc atc cgt tcg tcc atc cat cca tcc atc aac      240
 Pro Phe Ile Tyr Pro Ser Ile Arg Ser Ser Ile His Pro Ser Ile Asn
  65                  70                  75                  80

 cca tcc tcc cat tca ttt acc cat cca tcc att cat cca tgc atc cat      288
 Pro Ser Ser His Ser Phe Thr His Pro Ser Ile His Pro Cys Ile His
                  85                  90                  95

 cca tcc atg cgt gca tcc atc cat cca ttt atc cat cca tcc atc cat      336
 Pro Ser Met Arg Ala Ser Ile His Pro Phe Ile His Pro Ser Ile His
             100                 105                 110

 cca tcc gtc gtc cca ttc ctt tat cca tcc gtt aat gca cct gtc cat      384
 Pro Ser Val Val Pro Phe Leu Tyr Pro Ser Val Asn Ala Pro Val His
         115                 120                 125

 cca tcc atc cat tct cca ttc atc ttt cca tcc atg cat cat cca tgc      432
 Pro Ser Ile His Ser Pro Phe Ile Phe Pro Ser Met His His Pro Cys
     130                 135                 140

 atc cat cct ttt agt tca tcc agc cac tca tca att gat aca tcc atc      480
 Ile His Pro Phe Ser Ser Ser Ser His Ser Ser Ile Asp Thr Ser Ile
 145                 150                 155                 160

 tgt cca cca tcc act cat cta tcc atc cat tca ccc atc ctt tca tca      528
 Cys Pro Pro Ser Thr His Leu Ser Ile His Ser Pro Ile Leu Ser Ser
                 165                 170                 175

 att tac cca tct acc atc cat cca ttt atc cgt tca ccc att cat cta      576
 Ile Tyr Pro Ser Thr Ile His Pro Phe Ile Arg Ser Pro Ile His Leu
             180                 185                 190

 tcc atc tgt cca tcc atc cac cta tct gtt cat cca tcc atc cat tca      624
 Ser Ile Cys Pro Ser Ile His Leu Ser Val His Pro Ser Ile His Ser
         195                 200                 205

 tct atc cat cca tcc acc tac tca ccc acc cac cca tcc atc cac cca      672
 Ser Ile His Pro Ser Thr Tyr Ser Pro Thr His Pro Ser Ile His Pro
     210                 215                 220

 ccc aac cat cca tcc acc caa cca tcc atc cat acc tcc atc cgt cta      720
 Pro Asn His Pro Ser Thr Gln Pro Ser Ile His Thr Ser Ile Arg Leu
 225                 230                 235                 240

 ccc acc cac tca tcc act taa                                          741
 Pro Thr His Ser Ser Thr 
                 245





      <210> 836
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 836
  atg ttg ctc aca caa agc ctg ttt ggt ggt ctc ttc aca cgg acg tgc      48
  Met Leu Leu Thr Gln Ser Leu Phe Gly Gly Leu Phe Thr Arg Thr Cys
    1               5                  10                  15

 atg aaa ttt tgc gct gtg act cga atc ggg gga cct ccc ttg gga gat       96
 Met Lys Phe Cys Ala Val Thr Arg Ile Gly Gly Pro Pro Leu Gly Asp
              20                  25                  30

 caa tcc ctg tac tcc tgt tct ttg ctc cgt gag aaa gat cca cct atg      144
 Gln Ser Leu Tyr Ser Cys Ser Leu Leu Arg Glu Lys Asp Pro Pro Met
          35                  40                  45

 acc tca ggt cct cag acc gac cag ccc aag gaa cat gtc acc aat ttt      192
 Thr Ser Gly Pro Gln Thr Asp Gln Pro Lys Glu His Val Thr Asn Phe
      50                  55                  60

 aaa tca ggt tgc tgc aat att gca ggc tcc ttg gtg ttt atg atg aag      240
 Lys Ser Gly Cys Cys Asn Ile Ala Gly Ser Leu Val Phe Met Met Lys
  65                  70                  75                  80

 ctt tat gta gtt gaa gtc aaa gga cat act aaa gtt gtc aca ata ttt      288
 Leu Tyr Val Val Glu Val Lys Gly His Thr Lys Val Val Thr Ile Phe
                  85                  90                  95

 cca aac gat atc acg gtg cca gct ata tga                              318
 Pro Asn Asp Ile Thr Val Pro Ala Ile 
             100                 105





      <210> 837
      <211> 732
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(732)

      <400> 837
  atg gcg gca gcc agc gct ggg gca acc cgg ctg ctc ctg ctc ttg ctg      48
  Met Ala Ala Ala Ser Ala Gly Ala Thr Arg Leu Leu Leu Leu Leu Leu
    1               5                  10                  15

 atg gcg gta gca gcg ccc agt cga gcc cgg ggc agc ggc tgc cgg gcc       96
 Met Ala Val Ala Ala Pro Ser Arg Ala Arg Gly Ser Gly Cys Arg Ala
              20                  25                  30

 ggg act ggt gcg cga ggg gct ggg gcg gaa ggt cga gag ggc gag gcc      144
 Gly Thr Gly Ala Arg Gly Ala Gly Ala Glu Gly Arg Glu Gly Glu Ala
          35                  40                  45

 tgt ggc acg gtg ggg ctg ctg ctg gag cac tca ttt gag atc gat gac      192
 Cys Gly Thr Val Gly Leu Leu Leu Glu His Ser Phe Glu Ile Asp Asp
      50                  55                  60

 agt gcc aac ttc cgg aag cgg ggc tca ctg ctc tgg aac cag cag gat      240
 Ser Ala Asn Phe Arg Lys Arg Gly Ser Leu Leu Trp Asn Gln Gln Asp
  65                  70                  75                  80

 ggt acc ttg tcc ctg tca cag cgg cag ctc agc gag gag gag cgg ggc      288
 Gly Thr Leu Ser Leu Ser Gln Arg Gln Leu Ser Glu Glu Glu Arg Gly
                  85                  90                  95

 cga ctc cgg gat gtg gca gcc ctg aat ggc ctg tac cgg gtc cgg atc      336
 Arg Leu Arg Asp Val Ala Ala Leu Asn Gly Leu Tyr Arg Val Arg Ile
             100                 105                 110

 cca agg cga ccc ggg gcc ctg gat ggc tgg aag ctg tgc tcc ctg gtg      384
 Pro Arg Arg Pro Gly Ala Leu Asp Gly Trp Lys Leu Cys Ser Leu Val
         115                 120                 125

 gag tcg cac ctg tcg gac cag ctg acc ctg cac gtg gat gtg gcc ggc      432
 Glu Ser His Leu Ser Asp Gln Leu Thr Leu His Val Asp Val Ala Gly
     130                 135                 140

 aac gtg gtg ggc gtg tcg gtg gtg acg cac ccc ggg ggc tgc cgg ggc      480
 Asn Val Val Gly Val Ser Val Val Thr His Pro Gly Gly Cys Arg Gly
 145                 150                 155                 160

 cat gag gtg gag gac gtg gac ctg gag ctg ttc aac acc tcg gtg cag      528
 His Glu Val Glu Asp Val Asp Leu Glu Leu Phe Asn Thr Ser Val Gln
                 165                 170                 175

 ctg cag ccg ccc acc aca gcc cca ggc cct gag acg gcg gcc ttc att      576
 Leu Gln Pro Pro Thr Thr Ala Pro Gly Pro Glu Thr Ala Ala Phe Ile
             180                 185                 190

 gag cgc ctg gag atg gaa cat gcc cag aag gcc aag aac ccc cag gag      624
 Glu Arg Leu Glu Met Glu His Ala Gln Lys Ala Lys Asn Pro Gln Glu
         195                 200                 205

 cag aag tcc ttc ttc gcc aaa tac gag ata gct tat gct ttt tct gtc      672
 Gln Lys Ser Phe Phe Ala Lys Tyr Glu Ile Ala Tyr Ala Phe Ser Val
     210                 215                 220

 ttc att cca tgt gaa tcc tgc ttc att ctt ttc cta gag gat tcc cga      720
 Phe Ile Pro Cys Glu Ser Cys Phe Ile Leu Phe Leu Glu Asp Ser Arg
 225                 230                 235                 240

 aat att tac taa                                                      732
 Asn Ile Tyr 






      <210> 838
      <211> 435
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(435)

      <400> 838
  atg cgg aga gca gca gcg ctg tct cat ggg gcc gtg ttc atc ctg ctg      48
  Met Arg Arg Ala Ala Ala Leu Ser His Gly Ala Val Phe Ile Leu Leu
    1               5                  10                  15

 tgc cat ctg tgg cgt ggg ctg cct ggt tct acc tct cag tgc cct ggt       96
 Cys His Leu Trp Arg Gly Leu Pro Gly Ser Thr Ser Gln Cys Pro Gly
              20                  25                  30

 ttg tgg tgg ttc atg ctg ctg cac cct gtc agc agg tcc atg cca tct      144
 Leu Trp Trp Phe Met Leu Leu His Pro Val Ser Arg Ser Met Pro Ser
          35                  40                  45

 gac aca gcc aga act gtc atg gtc ctg ctg ttc cac atc tat gac gag      192
 Asp Thr Ala Arg Thr Val Met Val Leu Leu Phe His Ile Tyr Asp Glu
      50                  55                  60

 ctg cag gag tgg ggc agg act gag gat tta gat tta cct tgt gac agt      240
 Leu Gln Glu Trp Gly Arg Thr Glu Asp Leu Asp Leu Pro Cys Asp Ser
  65                  70                  75                  80

 gcc aaa ggg gca aat gtg gtc ctt ctg agg ccc tcc acc tgc cag gac      288
 Ala Lys Gly Ala Asn Val Val Leu Leu Arg Pro Ser Thr Cys Gln Asp
                  85                  90                  95

 cac ttg ccg gga ccg gca agc ctg cac caa cac aca gca gaa tgg aaa      336
 His Leu Pro Gly Pro Ala Ser Leu His Gln His Thr Ala Glu Trp Lys
             100                 105                 110

 gtt cct tgg ctt aga gtc cag aca tac tgg ttc tac cca act gcc tgt      384
 Val Pro Trp Leu Arg Val Gln Thr Tyr Trp Phe Tyr Pro Thr Ala Cys
         115                 120                 125

 aaa gtc agg tgc cag ctg ttt aac ccc aaa caa gtt act cat ctt ctt      432
 Lys Val Arg Cys Gln Leu Phe Asn Pro Lys Gln Val Thr His Leu Leu
     130                 135                 140

 tga                                                                  435
 






      <210> 839
      <211> 252
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(252)

      <400> 839
  atg ctt tct tat gtg ttc tgt gtc tcc ctc tct tgg gtc act tct tct      48
  Met Leu Ser Tyr Val Phe Cys Val Ser Leu Ser Trp Val Thr Ser Ser
    1               5                  10                  15

 gtg gaa aat cag ctg ctg ttg tta gca gca ctg tgg aga ggc cca cat       96
 Val Glu Asn Gln Leu Leu Leu Leu Ala Ala Leu Trp Arg Gly Pro His
              20                  25                  30

 ggc gag aaa ctg aag tct ctg gcc aac agc cat atg aga aac cga gca      144
 Gly Glu Lys Leu Lys Ser Leu Ala Asn Ser His Met Arg Asn Arg Ala
          35                  40                  45

 gaa ata gta gtg att aca ctg cac aaa tac aat ata gct gaa cct ctt      192
 Glu Ile Val Val Ile Thr Leu His Lys Tyr Asn Ile Ala Glu Pro Leu
      50                  55                  60

 gag ctg aaa gga agt tcc aaa att tat ggt tca ttt ctg ggg aag tct      240
 Glu Leu Lys Gly Ser Ser Lys Ile Tyr Gly Ser Phe Leu Gly Lys Ser
  65                  70                  75                  80

 gag cat ttc taa                                                      252
 Glu His Phe 






      <210> 840
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 840
  atg tcc aca gcc aga gct cca aag ccc tgc cgg ccc tgg tgc cac tgc      48
  Met Ser Thr Ala Arg Ala Pro Lys Pro Cys Arg Pro Trp Cys His Cys
    1               5                  10                  15

 cgc ctc tgc gtc cgg agc ctg tgg ggc tca gct ctg ctg ctc tgg ccc       96
 Arg Leu Cys Val Arg Ser Leu Trp Gly Ser Ala Leu Leu Leu Trp Pro
              20                  25                  30

 aag tct ggc ctg gag tcc ccg gtg ccc ttt gca ggc acg gag gca gct      144
 Lys Ser Gly Leu Glu Ser Pro Val Pro Phe Ala Gly Thr Glu Ala Ala
          35                  40                  45

 gga cat cct tcg ctt cac cag cct ctg ggc ctg caa gcg ctt ctg gag      192
 Gly His Pro Ser Leu His Gln Pro Leu Gly Leu Gln Ala Leu Leu Glu
      50                  55                  60

 cgt ttc att ttc ctt cag agt gag gaa gag ttt ttt tct tca ggg aat      240
 Arg Phe Ile Phe Leu Gln Ser Glu Glu Glu Phe Phe Ser Ser Gly Asn
  65                  70                  75                  80

 cta agt cca aaa ggg cat agc tgt gat cag atg gct gct tgt cgg ggg      288
 Leu Ser Pro Lys Gly His Ser Cys Asp Gln Met Ala Ala Cys Arg Gly
                  85                  90                  95

 gcc ttc tca agc ctg cag ggc cgg ccg gcc ggc caa cag tct ctg ctg      336
 Ala Phe Ser Ser Leu Gln Gly Arg Pro Ala Gly Gln Gln Ser Leu Leu
             100                 105                 110

 ctt gcg gac tcc gtg gcg aga tct gtt tta cgg ggc ctt tgg cat ttg      384
 Leu Ala Asp Ser Val Ala Arg Ser Val Leu Arg Gly Leu Trp His Leu
         115                 120                 125

 ggg gca act gaa gct ctt caa gcg cag tgt cca tgt ttc tcc cag ggc      432
 Gly Ala Thr Glu Ala Leu Gln Ala Gln Cys Pro Cys Phe Ser Gln Gly
     130                 135                 140

 tgt cct ctc cgg ccc ccg cct cag gga gga cct ttt ctt tct gag aag      480
 Cys Pro Leu Arg Pro Pro Pro Gln Gly Gly Pro Phe Leu Ser Glu Lys
 145                 150                 155                 160

 agc tgg cat ttc ctc tct cac tgg cag tgt gtg tgt tct ccc tca cct      528
 Ser Trp His Phe Leu Ser His Trp Gln Cys Val Cys Ser Pro Ser Pro
                 165                 170                 175

 gcg gtg gaa ggt gag ctg ctt cct gcg gct gct gta gcg gtt gca gca      576
 Ala Val Glu Gly Glu Leu Leu Pro Ala Ala Ala Val Ala Val Ala Ala
             180                 185                 190

 ctg cca ggc cgc gca cga ctt cgg cat ctc cgg cca ggc ctg gct gcc      624
 Leu Pro Gly Arg Ala Arg Leu Arg His Leu Arg Pro Gly Leu Ala Ala
         195                 200                 205

 cgt aac aaa gat ggc ggc agc ggg gcc gga tgt att tat ttt gtt atc      672
 Arg Asn Lys Asp Gly Gly Ser Gly Ala Gly Cys Ile Tyr Phe Val Ile
     210                 215                 220

 ttc taa                                                              678
 Phe 
 225





      <210> 841
      <211> 735
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(735)

      <400> 841
  atg act gaa gga cag ttt ggc tgg act gtg ttg tcc tta gga gca tat      48
  Met Thr Glu Gly Gln Phe Gly Trp Thr Val Leu Ser Leu Gly Ala Tyr
    1               5                  10                  15

 atg gtg ggg cca gcg cta tcc atg gag att cag tat aaa gga tat tgg       96
 Met Val Gly Pro Ala Leu Ser Met Glu Ile Gln Tyr Lys Gly Tyr Trp
              20                  25                  30

 gac cct tgg ctg cag cag caa gtc ttg gtc cca gca aaa tgc tca gtt      144
 Asp Pro Trp Leu Gln Gln Gln Val Leu Val Pro Ala Lys Cys Ser Val
          35                  40                  45

 caa ctt gag ttt aaa acg gtc tta gtc att ctg tcc cct gaa tca ctt      192
 Gln Leu Glu Phe Lys Thr Val Leu Val Ile Leu Ser Pro Glu Ser Leu
      50                  55                  60

 cct gtt tca ggt ttc tac ttt gca gag aaa gaa aca caa aca ggc ctg      240
 Pro Val Ser Gly Phe Tyr Phe Ala Glu Lys Glu Thr Gln Thr Gly Leu
  65                  70                  75                  80

 cag ctg gct gtc acc aag cca cta cag aag ccc cac cgg cag gaa ggg      288
 Gln Leu Ala Val Thr Lys Pro Leu Gln Lys Pro His Arg Gln Glu Gly
                  85                  90                  95

 atc cag ggc agg gag gga tcc agg cca gtc cca gag cag gga cca ggc      336
 Ile Gln Gly Arg Glu Gly Ser Arg Pro Val Pro Glu Gln Gly Pro Gly
             100                 105                 110

 agc gct cac gtg cgc tct gca cca gcc aca ggg atg cgg gga cgc tgg      384
 Ser Ala His Val Arg Ser Ala Pro Ala Thr Gly Met Arg Gly Arg Trp
         115                 120                 125

 gga cgc ggg gat gcg ggg aca ccg ggg acc gcc cgg gag cac gtc ctg      432
 Gly Arg Gly Asp Ala Gly Thr Pro Gly Thr Ala Arg Glu His Val Leu
     130                 135                 140

 cgc atc gcc ggg ctc cgc gag gcc tgc aga gga cgc agc cct ctc cct      480
 Arg Ile Ala Gly Leu Arg Glu Ala Cys Arg Gly Arg Ser Pro Leu Pro
 145                 150                 155                 160

 ccc gct gga aaa cag gca ggc tct acc agt cag gat aac act tca ttc      528
 Pro Ala Gly Lys Gln Ala Gly Ser Thr Ser Gln Asp Asn Thr Ser Phe
                 165                 170                 175

 att gca cac gct agg gct tta att cat ggg acc cca cct gtc ctc ctc      576
 Ile Ala His Ala Arg Ala Leu Ile His Gly Thr Pro Pro Val Leu Leu
             180                 185                 190

 aaa ata gtc ctg ggt cct cta gga atg ccc tcc aac cac caa gtg gag      624
 Lys Ile Val Leu Gly Pro Leu Gly Met Pro Ser Asn His Gln Val Glu
         195                 200                 205

 aga ctg ctt gag aaa caa gaa aga aaa gca ggg cca cga cac agg aga      672
 Arg Leu Leu Glu Lys Gln Glu Arg Lys Ala Gly Pro Arg His Arg Arg
     210                 215                 220

 caa aac ctg gcc cac aca gct ggg gcc cct gga tca gcc atg cct aac      720
 Gln Asn Leu Ala His Thr Ala Gly Ala Pro Gly Ser Ala Met Pro Asn
 225                 230                 235                 240

 cag gta gtg act tga                                                  735
 Gln Val Val Thr 






      <210> 842
      <211> 1167
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1167)

      <400> 842
  atg ggg gtg gcc aga agg aag ttc ctc agg ttc ttc ttc aac ccc ctg      48
  Met Gly Val Ala Arg Arg Lys Phe Leu Arg Phe Phe Phe Asn Pro Leu
    1               5                  10                  15

 cac ctg tgc tca tgg atc aag gat gag tgg agc ctc atc tac gag ccg       96
 His Leu Cys Ser Trp Ile Lys Asp Glu Trp Ser Leu Ile Tyr Glu Pro
              20                  25                  30

 gcc cac gtg aag gag aac tgg atc gac ccc ctg atg aga tgg cag cca      144
 Ala His Val Lys Glu Asn Trp Ile Asp Pro Leu Met Arg Trp Gln Pro
          35                  40                  45

 gag gtc cag gag ctg atc aac cac ctg gag ggc gtg tct gcc agt caa      192
 Glu Val Gln Glu Leu Ile Asn His Leu Glu Gly Val Ser Ala Ser Gln
      50                  55                  60

 tcc tct cct tta aag acc aag gcc aag gtc aca gag ccc aag gaa ttc      240
 Ser Ser Pro Leu Lys Thr Lys Ala Lys Val Thr Glu Pro Lys Glu Phe
  65                  70                  75                  80

 aac ctg act gcc ccc agg ccc cgc acc att cca gcg ccc gaa cca gtc      288
 Asn Leu Thr Ala Pro Arg Pro Arg Thr Ile Pro Ala Pro Glu Pro Val
                  85                  90                  95

 ccg gtc gtg gcc aag ccg aga ccc gtg agt gtg ggc att ctc agc agg      336
 Pro Val Val Ala Lys Pro Arg Pro Val Ser Val Gly Ile Leu Ser Arg
             100                 105                 110

 cac tgg ctt gca ggc atc agg cct agt cat ggc tca aag cag aac ctc      384
 His Trp Leu Ala Gly Ile Arg Pro Ser His Gly Ser Lys Gln Asn Leu
         115                 120                 125

 agt aaa tac cag ttg gat gga tgg atg ggt gga tgg att atc aga tgg      432
 Ser Lys Tyr Gln Leu Asp Gly Trp Met Gly Gly Trp Ile Ile Arg Trp
     130                 135                 140

 atg gta gat gga tgg gtg gat gaa tgg atg gat gga tgg atg gat gat      480
 Met Val Asp Gly Trp Val Asp Glu Trp Met Asp Gly Trp Met Asp Asp
 145                 150                 155                 160

 tgg att gct gct gac cat agg ctc ttc ctc cca cca ctt cag cag gtc      528
 Trp Ile Ala Ala Asp His Arg Leu Phe Leu Pro Pro Leu Gln Gln Val
                 165                 170                 175

 ccc cag agc acc tac cag cca ccc aag gag cag cag cag ctg gag aca      576
 Pro Gln Ser Thr Tyr Gln Pro Pro Lys Glu Gln Gln Gln Leu Glu Thr
             180                 185                 190

 gtc aag agg tac aac cgc cga aag gcc gag gag ctg ctg ctg agg gca      624
 Val Lys Arg Tyr Asn Arg Arg Lys Ala Glu Glu Leu Leu Leu Arg Ala
         195                 200                 205

 aac atc gag gaa ctg cgc tgc gcc atg ccc agg tcc tgc agg gag cga      672
 Asn Ile Glu Glu Leu Arg Cys Ala Met Pro Arg Ser Cys Arg Glu Arg
     210                 215                 220

 gtg cag ggc tcc aag cag cag ctg cgg ctt cag ttc cca ccc cga atc      720
 Val Gln Gly Ser Lys Gln Gln Leu Arg Leu Gln Phe Pro Pro Arg Ile
 225                 230                 235                 240

 cga aag act ccg aag ctg acc ttc tat agg cct gac aac atc ctg gtc      768
 Arg Lys Thr Pro Lys Leu Thr Phe Tyr Arg Pro Asp Asn Ile Leu Val
                 245                 250                 255

 aag ctg aac acc aca gcc atc ctg cga gaa ggg gcc ttg tac cag cgg      816
 Lys Leu Asn Thr Thr Ala Ile Leu Arg Glu Gly Ala Leu Tyr Gln Arg
             260                 265                 270

 cag gtg gag cag gag ctg cag agg gtt gat aag ctc gtg gat ggg gct      864
 Gln Val Glu Gln Glu Leu Gln Arg Val Asp Lys Leu Val Asp Gly Ala
         275                 280                 285

 ggg gac ttc tct gag ttc ttc gag tgg cag aag aag atg cag gcg aag      912
 Gly Asp Phe Ser Glu Phe Phe Glu Trp Gln Lys Lys Met Gln Ala Lys
     290                 295                 300

 gac cgg gag gag cag ctg gct gca agc gag tgc cgg cgg ttg caa ggg      960
 Asp Arg Glu Glu Gln Leu Ala Ala Ser Glu Cys Arg Arg Leu Gln Gly
 305                 310                 315                 320

 aag ctt agc cat gag gag gcc gtc cta gcc cgg cag agc ctc atg cag     1008
 Lys Leu Ser His Glu Glu Ala Val Leu Ala Arg Gln Ser Leu Met Gln
                 325                 330                 335

 gag aac aag cag agg gtg gag cag cag aag gag cag gtg ggt gcc atg     1056
 Glu Asn Lys Gln Arg Val Glu Gln Gln Lys Glu Gln Val Gly Ala Met
             340                 345                 350

 cag ggc agc tgg gca tgg ggc agc cag ctg aac tgt gtg ccc acc ggg     1104
 Gln Gly Ser Trp Ala Trp Gly Ser Gln Leu Asn Cys Val Pro Thr Gly
         355                 360                 365

 agc tgc agg gcc agg gct ggc agt gga gct gag tgt cca cag cgc ccc     1152
 Ser Cys Arg Ala Arg Ala Gly Ser Gly Ala Glu Cys Pro Gln Arg Pro
     370                 375                 380

 cgt aga agc tac tga                                                 1167
 Arg Arg Ser Tyr 
 385





      <210> 843
      <211> 201
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(201)

      <400> 843
  atg acc atg cgc atg tcc agc ccc tcc tgg acc cag atc ttg ctc atg      48
  Met Thr Met Arg Met Ser Ser Pro Ser Trp Thr Gln Ile Leu Leu Met
    1               5                  10                  15

 atg cga atc atc tgc agc gtt agc atg tcc tgg cga agt agt cgg tat       96
 Met Arg Ile Ile Cys Ser Val Ser Met Ser Trp Arg Ser Ser Arg Tyr
              20                  25                  30

 gaa aac cac ccc ctg aga agt gtg gac acc ctc cag aag atc ctt aag      144
 Glu Asn His Pro Leu Arg Ser Val Asp Thr Leu Gln Lys Ile Leu Lys
          35                  40                  45

 gag gag gac ccc cta cac ccc agc ctg gga ctg tac gct aac agc aag      192
 Glu Glu Asp Pro Leu His Pro Ser Leu Gly Leu Tyr Ala Asn Ser Lys
      50                  55                  60

 acc aaa tag                                                          201
 Thr Lys 
  65





      <210> 844
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 844
  atg ctg agg agc tgt gct gcg tgc ctc cgc atg ctg ggg tcc ctg cgc      48
  Met Leu Arg Ser Cys Ala Ala Cys Leu Arg Met Leu Gly Ser Leu Arg
    1               5                  10                  15

 cca cca ccg aag aag cag ttg tcc cct gaa tac tct gct ccc tca ctg       96
 Pro Pro Pro Lys Lys Gln Leu Ser Pro Glu Tyr Ser Ala Pro Ser Leu
              20                  25                  30

 ctg aat ccc tgt agg gag aag cct gcc aac agt gac ctt ctg aaa cag      144
 Leu Asn Pro Cys Arg Glu Lys Pro Ala Asn Ser Asp Leu Leu Lys Gln
          35                  40                  45

 cct tct gaa tac gag gag gat tca gtt tcc atc ttc tca act ttt taa      192
 Pro Ser Glu Tyr Glu Glu Asp Ser Val Ser Ile Phe Ser Thr Phe 
      50                  55                  60





      <210> 845
      <211> 324
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(324)

      <400> 845
  atg ggc tgt gcg ttc agc agt tgg ttt cac cac ctg gta ctg gtt gat      48
  Met Gly Cys Ala Phe Ser Ser Trp Phe His His Leu Val Leu Val Asp
    1               5                  10                  15

 cac ctt gac tgt ctg gtc atc gat gcg cag cca gcc att cag acc gat       96
 His Leu Asp Cys Leu Val Ile Asp Ala Gln Pro Ala Ile Gln Thr Asp
              20                  25                  30

 ctg gaa gac gtc tct agt gta atg gcc acc cgt cgc act gtt gcc gtg      144
 Leu Glu Asp Val Ser Ser Val Met Ala Thr Arg Arg Thr Val Ala Val
          35                  40                  45

 atg gta gac cac tgc aaa gag ccg ata gct ctc cag tgc atc ctg gac      192
 Met Val Asp His Cys Lys Glu Pro Ile Ala Leu Gln Cys Ile Leu Asp
      50                  55                  60

 tgt gcg tat ttt gtc aga ctg gat atc caa ctg caa cgt gaa aaa tgg      240
 Cys Ala Tyr Phe Val Arg Leu Asp Ile Gln Leu Gln Arg Glu Lys Trp
  65                  70                  75                  80

 ctg caa agt ggc aga ttc ttt tgc act ctg ctg gta aac cac aga cct      288
 Leu Gln Ser Gly Arg Phe Phe Cys Thr Leu Leu Val Asn His Arg Pro
                  85                  90                  95

 gat gtg gcc acc aaa aat gtg gtg att gga gtc tga                      324
 Asp Val Ala Thr Lys Asn Val Val Ile Gly Val 
             100                 105





      <210> 846
      <211> 552
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(552)

      <400> 846
  atg ggc tcc agg ctg ctc tgt tgg gtg ctg ctt tgt ctc ctg gga gca      48
  Met Gly Ser Arg Leu Leu Cys Trp Val Leu Leu Cys Leu Leu Gly Ala
    1               5                  10                  15

 ggc cca gta aag gct gga gtc act caa act cca aga tat ctg atc aaa       96
 Gly Pro Val Lys Ala Gly Val Thr Gln Thr Pro Arg Tyr Leu Ile Lys
              20                  25                  30

 acg aga gga cag caa gtg aca ctg agc tgc tcc cct atc tct ggg cat      144
 Thr Arg Gly Gln Gln Val Thr Leu Ser Cys Ser Pro Ile Ser Gly His
          35                  40                  45

 agg agt gta tcc tgg tac caa cag acc cca gga cag ggc ctt cag ttc      192
 Arg Ser Val Ser Trp Tyr Gln Gln Thr Pro Gly Gln Gly Leu Gln Phe
      50                  55                  60

 ctc ttt gaa tac ttc agt gag aca cag aga aac aaa gga aac ttc cct      240
 Leu Phe Glu Tyr Phe Ser Glu Thr Gln Arg Asn Lys Gly Asn Phe Pro
  65                  70                  75                  80

 ggt cga ttc tca ggg cgc cag ttc tct aac tct cgc tct gag atg aat      288
 Gly Arg Phe Ser Gly Arg Gln Phe Ser Asn Ser Arg Ser Glu Met Asn
                  85                  90                  95

 gtg agc acc ttg gag ctg ggg gac tcg gcc ctt tat ctt tgc gcc agc      336
 Val Ser Thr Leu Glu Leu Gly Asp Ser Ala Leu Tyr Leu Cys Ala Ser
             100                 105                 110

 agc ttg gca cag ccc tac aaa gcc aac cac att ctg tgc aca aac ctc      384
 Ser Leu Ala Gln Pro Tyr Lys Ala Asn His Ile Leu Cys Thr Asn Leu
         115                 120                 125

 cct ggc cca atg tgg agc aac ctc agc cct gac ata tct ttg agg ggc      432
 Pro Gly Pro Met Trp Ser Asn Leu Ser Pro Asp Ile Ser Leu Arg Gly
     130                 135                 140

 tgt gcg gga cag gaa ggc tgc atg gag ctg ctg agc ctg agt ctt tca      480
 Cys Ala Gly Gln Glu Gly Cys Met Glu Leu Leu Ser Leu Ser Leu Ser
 145                 150                 155                 160

 atg ggt gaa caa ggc agg agt ggc ctg cag aaa gag tac ctg gaa aag      528
 Met Gly Glu Gln Gly Arg Ser Gly Leu Gln Lys Glu Tyr Leu Glu Lys
                 165                 170                 175

 gac tgt acc cga aga att ggg tga                                      552
 Asp Cys Thr Arg Arg Ile Gly 
             180





      <210> 847
      <211> 654
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(654)

      <400> 847
  atg agc tta atc caa gct gta acc atg gtt act gtt ttc ccc agg ctg      48
  Met Ser Leu Ile Gln Ala Val Thr Met Val Thr Val Phe Pro Arg Leu
    1               5                  10                  15

 gcc cta ctt gtt ggg cca cag ctg gct cgt acc tgc tgt ctt gcc cat       96
 Ala Leu Leu Val Gly Pro Gln Leu Ala Arg Thr Cys Cys Leu Ala His
              20                  25                  30

 tgc tgc cca ccc tgc cat tct cat gag agt gtt aat att tac ccc aga      144
 Cys Cys Pro Pro Cys His Ser His Glu Ser Val Asn Ile Tyr Pro Arg
          35                  40                  45

 gat ttc ctc ttt caa gag ctc aaa gcc cta agg atc ttt gag gtt cta      192
 Asp Phe Leu Phe Gln Glu Leu Lys Ala Leu Arg Ile Phe Glu Val Leu
      50                  55                  60

 ggt gct gta ggt ctg aga gtt gga agg gat ctt cag gat cac aga agt      240
 Gly Ala Val Gly Leu Arg Val Gly Arg Asp Leu Gln Asp His Arg Ser
  65                  70                  75                  80

 tcc acg tct tat cct gta gca tcc ttg aga tac ggc tat cta gcc ttt      288
 Ser Thr Ser Tyr Pro Val Ala Ser Leu Arg Tyr Gly Tyr Leu Ala Phe
                  85                  90                  95

 gct tca ctc ttg aaa gat ggt cct ggt tac tgg gtg aag att cat cac      336
 Ala Ser Leu Leu Lys Asp Gly Pro Gly Tyr Trp Val Lys Ile His His
             100                 105                 110

 tta gaa tat aca gat gga gga atc ctg gat cca gat gat gtc ttg gca      384
 Leu Glu Tyr Thr Asp Gly Gly Ile Leu Asp Pro Asp Asp Val Leu Ala
         115                 120                 125

 gat gtt gtt gaa gat aaa gac aag agc tct tgg ttg act tac ttg gaa      432
 Asp Val Val Glu Asp Lys Asp Lys Ser Ser Trp Leu Thr Tyr Leu Glu
     130                 135                 140

 atg gaa gta cct agt gtt aag act gag gaa cct ggg act aca att gag      480
 Met Glu Val Pro Ser Val Lys Thr Glu Glu Pro Gly Thr Thr Ile Glu
 145                 150                 155                 160

 aag aga ggg ttc aga ggg agc ctg cta act gtc ctc aac tat ttg agt      528
 Lys Arg Gly Phe Arg Gly Ser Leu Leu Thr Val Leu Asn Tyr Leu Ser
                 165                 170                 175

 gat cat aga aaa ggt ata aat tca ttc cct att gct cta aga aat cgg      576
 Asp His Arg Lys Gly Ile Asn Ser Phe Pro Ile Ala Leu Arg Asn Arg
             180                 185                 190

 gcc agt ggt gtt tca aga aaa tct ttt tca gct gaa tat aat gaa cag      624
 Ala Ser Gly Val Ser Arg Lys Ser Phe Ser Ala Glu Tyr Asn Glu Gln
         195                 200                 205

 ctt ctc aat gaa gca cat gct gct ttc taa                              654
 Leu Leu Asn Glu Ala His Ala Ala Phe 
     210                 215





      <210> 848
      <211> 918
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(918)

      <400> 848
  atg ggg ggc acc ctg gca tgg acg ctg ctg ttg ccg ctg ctg ctg cgg      48
  Met Gly Gly Thr Leu Ala Trp Thr Leu Leu Leu Pro Leu Leu Leu Arg
    1               5                  10                  15

 gag tca gac agc cta gaa ccg tcg tgc acc gtg tcc tcc gcg gat gtg       96
 Glu Ser Asp Ser Leu Glu Pro Ser Cys Thr Val Ser Ser Ala Asp Val
              20                  25                  30

 gac tgg aac gcg gag ttc agt gcc acg tgc ctg aat ttc agt ggc ctc      144
 Asp Trp Asn Ala Glu Phe Ser Ala Thr Cys Leu Asn Phe Ser Gly Leu
          35                  40                  45

 agc ctg agc ctg cct cac aac cag tct ctg cgg gcc agc aac gtg att      192
 Ser Leu Ser Leu Pro His Asn Gln Ser Leu Arg Ala Ser Asn Val Ile
      50                  55                  60

 ctc ctt gac ctg tct ggg aac ggc ctg cga gag ctt cca gtg acc ttc      240
 Leu Leu Asp Leu Ser Gly Asn Gly Leu Arg Glu Leu Pro Val Thr Phe
  65                  70                  75                  80

 ttt gcc cac ctg cag aag ctt gag gtc ctg aac gtg cta cgc aac ccc      288
 Phe Ala His Leu Gln Lys Leu Glu Val Leu Asn Val Leu Arg Asn Pro
                  85                  90                  95

 ttg tct cgt gtg gat ggg gcg ctg gcc gcc cgc tgt gac ctt gac ctg      336
 Leu Ser Arg Val Asp Gly Ala Leu Ala Ala Arg Cys Asp Leu Asp Leu
             100                 105                 110

 cag gcc gac tgc aac tgt gcc ctg gag tcc tgg cac gac atc cgc cga      384
 Gln Ala Asp Cys Asn Cys Ala Leu Glu Ser Trp His Asp Ile Arg Arg
         115                 120                 125

 gac aac tgc tct ggc cag aag cct ctg ctc tgc tgg gac aca acc agc      432
 Asp Asn Cys Ser Gly Gln Lys Pro Leu Leu Cys Trp Asp Thr Thr Ser
     130                 135                 140

 tcc cag cac aac ctc tct gcc ttc ctg gag gtc agc tgc gcc cct ggc      480
 Ser Gln His Asn Leu Ser Ala Phe Leu Glu Val Ser Cys Ala Pro Gly
 145                 150                 155                 160

 ctg gcc tct gca act atc ggg gca gtg gtg gtc agc ggg tgc ctg ctt      528
 Leu Ala Ser Ala Thr Ile Gly Ala Val Val Val Ser Gly Cys Leu Leu
                 165                 170                 175

 ctt gga ctt gcc atc gct ggc cct gtg ctg gcc tgg aga ctc tgg cga      576
 Leu Gly Leu Ala Ile Ala Gly Pro Val Leu Ala Trp Arg Leu Trp Arg
             180                 185                 190

 tgc cga gtg gcc aga agc cgg gag ctg aac aaa ccc tgg gct gct cag      624
 Cys Arg Val Ala Arg Ser Arg Glu Leu Asn Lys Pro Trp Ala Ala Gln
         195                 200                 205

 gat ggg ccc aag ccc ggt tta ggc ttg cag cca cgg tac ggc agc cgg      672
 Asp Gly Pro Lys Pro Gly Leu Gly Leu Gln Pro Arg Tyr Gly Ser Arg
     210                 215                 220

 agc gcc ccc aag ccc caa gtg gcc gtg cca tcc tgc ccc tcc act ccc      720
 Ser Ala Pro Lys Pro Gln Val Ala Val Pro Ser Cys Pro Ser Thr Pro
 225                 230                 235                 240

 gac tat gag aac atg ttt gtg ggc cag cca gca gcc gag cac cag tgg      768
 Asp Tyr Glu Asn Met Phe Val Gly Gln Pro Ala Ala Glu His Gln Trp
                 245                 250                 255

 gat gaa caa ggg gct cac cct tca gag gac aat gac ttt tac atc aac      816
 Asp Glu Gln Gly Ala His Pro Ser Glu Asp Asn Asp Phe Tyr Ile Asn
             260                 265                 270

 tac aag gac atc gac ctg gct tcc cag cct gtc tac tgt aac ctg cag      864
 Tyr Lys Asp Ile Asp Leu Ala Ser Gln Pro Val Tyr Cys Asn Leu Gln
         275                 280                 285

 tca ctg ggc cag gcc cca atg gat gaa gag gag tac gtg atc ccc ggg      912
 Ser Leu Gly Gln Ala Pro Met Asp Glu Glu Glu Tyr Val Ile Pro Gly
     290                 295                 300

 cac tga                                                              918
 His 
 305





      <210> 849
      <211> 294
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(294)

      <400> 849
  atg cgg ccc ctg ctc tgc gcg ctg acc gga ctg gcc ctg ctc cgc gcc      48
  Met Arg Pro Leu Leu Cys Ala Leu Thr Gly Leu Ala Leu Leu Arg Ala
    1               5                  10                  15

 gcg ggc tct ttg gcc gct gcc gaa ccc ttc agc cct ccg cga gga gac       96
 Ala Gly Ser Leu Ala Ala Ala Glu Pro Phe Ser Pro Pro Arg Gly Asp
              20                  25                  30

 tca gct cag agc aca gcg tgt gac aga cac atg gct gtg caa cgc cgt      144
 Ser Ala Gln Ser Thr Ala Cys Asp Arg His Met Ala Val Gln Arg Arg
          35                  40                  45

 cta gat gtc atg gag gag atg gta gag aag acc gtg gat cac ctg ggg      192
 Leu Asp Val Met Glu Glu Met Val Glu Lys Thr Val Asp His Leu Gly
      50                  55                  60

 aca gag gtg aaa ggc ctg ctg ggc ctg ctg gag gag ctg gcc tgg aac      240
 Thr Glu Val Lys Gly Leu Leu Gly Leu Leu Glu Glu Leu Ala Trp Asn
  65                  70                  75                  80

 ctg ccc ccg gga ccc ttc agc ccc gct ccc gac ctt ctc gga gat ggc      288
 Leu Pro Pro Gly Pro Phe Ser Pro Ala Pro Asp Leu Leu Gly Asp Gly
                  85                  90                  95

 ttc tga                                                              294
 Phe 






      <210> 850
      <211> 531
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(531)

      <400> 850
  atg agc cag aga gga ctc gaa gcc tca gtg ctc ctg gcc ctc tgt gag      48
  Met Ser Gln Arg Gly Leu Glu Ala Ser Val Leu Leu Ala Leu Cys Glu
    1               5                  10                  15

 gct gca gcc gtg tgc cct gga gta tct gca gcc ttg ggc ctc tgg aaa       96
 Ala Ala Ala Val Cys Pro Gly Val Ser Ala Ala Leu Gly Leu Trp Lys
              20                  25                  30

 gga aat caa ggc tca gca gaa gcc gtg tgc cca gcc ctg cac cag gga      144
 Gly Asn Gln Gly Ser Ala Glu Ala Val Cys Pro Ala Leu His Gln Gly
          35                  40                  45

 gag cag ggt cag tta gct gag ggg ctg cag gcc ctc tgc tgc agt gag      192
 Glu Gln Gly Gln Leu Ala Glu Gly Leu Gln Ala Leu Cys Cys Ser Glu
      50                  55                  60

 agg cag ctg gac atc aga gat gct gac ggc ccc acc agc cca cgc tcc      240
 Arg Gln Leu Asp Ile Arg Asp Ala Asp Gly Pro Thr Ser Pro Arg Ser
  65                  70                  75                  80

 ccc agc tcc ccc gtc tcc aga gtc gtg tac aac ggc aag agg acc agc      288
 Pro Ser Ser Pro Val Ser Arg Val Val Tyr Asn Gly Lys Arg Thr Ser
                  85                  90                  95

 agc ccc cgc tcc cca ccc agc agc agc gag atc ttc acc cca gcc cac      336
 Ser Pro Arg Ser Pro Pro Ser Ser Ser Glu Ile Phe Thr Pro Ala His
             100                 105                 110

 gag gag aac gtc cgc ttc att tac gaa gcc tgg cag ggt gtg gag cga      384
 Glu Glu Asn Val Arg Phe Ile Tyr Glu Ala Trp Gln Gly Val Glu Arg
         115                 120                 125

 gac ctg cga ggc cag gtg ccg ggt ggc gag cgg ggc ctg gtg gag gag      432
 Asp Leu Arg Gly Gln Val Pro Gly Gly Glu Arg Gly Leu Val Glu Glu
     130                 135                 140

 tat gtg gag aag gtc cct aac ccc agc ctg aag acc ttc aag ccc atc      480
 Tyr Val Glu Lys Val Pro Asn Pro Ser Leu Lys Thr Phe Lys Pro Ile
 145                 150                 155                 160

 gac ctg agt gac ctg aag cgc cgg agc acg cag gat gcc aag aag tcc      528
 Asp Leu Ser Asp Leu Lys Arg Arg Ser Thr Gln Asp Ala Lys Lys Ser
                 165                 170                 175

 tag                                                                  531
 






      <210> 851
      <211> 921
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(921)

      <400> 851
  atg gtc tca aac tcc tgg cta cag gct atc ctc ctg cct ctg tct ccc      48
  Met Val Ser Asn Ser Trp Leu Gln Ala Ile Leu Leu Pro Leu Ser Pro
    1               5                  10                  15

 aaa gcg ctg gga tta caa gca aaa atc caa aca tgt ctt ctg aag ctg       96
 Lys Ala Leu Gly Leu Gln Ala Lys Ile Gln Thr Cys Leu Leu Lys Leu
              20                  25                  30

 aca cta aac aca tca aga act aag gca atc gat gga aac tat ctg aat      144
 Thr Leu Asn Thr Ser Arg Thr Lys Ala Ile Asp Gly Asn Tyr Leu Asn
          35                  40                  45

 tca aat ctc agc tca gac tct tac cac ctg ggt gac cta aag gaa atg      192
 Ser Asn Leu Ser Ser Asp Ser Tyr His Leu Gly Asp Leu Lys Glu Met
      50                  55                  60

 gca gag ctg gct gat ggt cag ggg aaa ggg ctg ggg gag tac aga acc      240
 Ala Glu Leu Ala Asp Gly Gln Gly Lys Gly Leu Gly Glu Tyr Arg Thr
  65                  70                  75                  80

 cag gag atc ccc agt ccc tgc gat gta gga tcc cgg acc ccc ggc gct      288
 Gln Glu Ile Pro Ser Pro Cys Asp Val Gly Ser Arg Thr Pro Gly Ala
                  85                  90                  95

 aag tgg aga tgc gcc agc tgc ccc aca ctg gag aag gct caa aga aaa      336
 Lys Trp Arg Cys Ala Ser Cys Pro Thr Leu Glu Lys Ala Gln Arg Lys
             100                 105                 110

 caa atc cca ccc ttc gcc gca ggt gga ttc tcc tcc cct aga gct act      384
 Gln Ile Pro Pro Phe Ala Ala Gly Gly Phe Ser Ser Pro Arg Ala Thr
         115                 120                 125

 gtc cag ttg cta ctg gcc tcc agc aaa aca aac atc agt atg gac gga      432
 Val Gln Leu Leu Leu Ala Ser Ser Lys Thr Asn Ile Ser Met Asp Gly
     130                 135                 140

 agg agc agg acg cag ggc ggg gag ggt cac ctt tct ggg aga aaa gaa      480
 Arg Ser Arg Thr Gln Gly Gly Glu Gly His Leu Ser Gly Arg Lys Glu
 145                 150                 155                 160

 ggc cgc ggc cta gcg tac ctt ggg cgg aag tgg ctc tcc cta cgg aga      528
 Gly Arg Gly Leu Ala Tyr Leu Gly Arg Lys Trp Leu Ser Leu Arg Arg
                 165                 170                 175

 cct cct gga cta cgc ttc cca gaa ttc tcg acg gga tca ggg aga cgg      576
 Pro Pro Gly Leu Arg Phe Pro Glu Phe Ser Thr Gly Ser Gly Arg Arg
             180                 185                 190

 cct cag cct cct aga gcg gaa gtt acc cga cta cac ggg gct ccc aaa      624
 Pro Gln Pro Pro Arg Ala Glu Val Thr Arg Leu His Gly Ala Pro Lys
         195                 200                 205

 cta cac ttc cca gaa ttc cta gaa aaa ctc tcc act ctc tgc ctg cct      672
 Leu His Phe Pro Glu Phe Leu Glu Lys Leu Ser Thr Leu Cys Leu Pro
     210                 215                 220

 agg acg caa gtg cag ggt gcc aag cgg aga gcc tgg atc ata ttt cac      720
 Arg Thr Gln Val Gln Gly Ala Lys Arg Arg Ala Trp Ile Ile Phe His
 225                 230                 235                 240

 atg tgc cgg tcc caa agg aat tcc tta act ctc cct tcc tgg aac cga      768
 Met Cys Arg Ser Gln Arg Asn Ser Leu Thr Leu Pro Ser Trp Asn Arg
                 245                 250                 255

 aat gct tcc aaa ggc aga gag ctc cta tat ata ttt ctc tgt ttt ccc      816
 Asn Ala Ser Lys Gly Arg Glu Leu Leu Tyr Ile Phe Leu Cys Phe Pro
             260                 265                 270

 cgg agg acc gtg cat gaa agg cgc ctt ttt ggc gcg tgt gtc tct gac      864
 Arg Arg Thr Val His Glu Arg Arg Leu Phe Gly Ala Cys Val Ser Asp
         275                 280                 285

 cct gtg gat ctt ctg gac aat tcc cgg aat ttc ttg cag ggc agc act      912
 Pro Val Asp Leu Leu Asp Asn Ser Arg Asn Phe Leu Gln Gly Ser Thr
     290                 295                 300

 tcc cct taa                                                          921
 Ser Pro 
 305





      <210> 852
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 852
  atg agg aac ttg ctg ctg att cct gct ctt tct ttg caa act gag ggc      48
  Met Arg Asn Leu Leu Leu Ile Pro Ala Leu Ser Leu Gln Thr Glu Gly
    1               5                  10                  15

 agt gag aaa att gct gac cgc ttc tct aag aag acc cag acc tgc aag       96
 Ser Glu Lys Ile Ala Asp Arg Phe Ser Lys Lys Thr Gln Thr Cys Lys
              20                  25                  30

 aac tcg agg gaa agg aag atc ttg aaa gcc tct cat tca ctg ggt gct      144
 Asn Ser Arg Glu Arg Lys Ile Leu Lys Ala Ser His Ser Leu Gly Ala
          35                  40                  45

 tcc agc tcc aag tgt gtg gta atg gtt tca gag gga ttt gga gag aaa      192
 Ser Ser Ser Lys Cys Val Val Met Val Ser Glu Gly Phe Gly Glu Lys
      50                  55                  60

 cag aat agt cga act tac ctc atc aaa cga ctc cag ttt tta ttg tcc      240
 Gln Asn Ser Arg Thr Tyr Leu Ile Lys Arg Leu Gln Phe Leu Leu Ser
  65                  70                  75                  80

 ccc cat aaa gat agt cta aac ctg ctc ccc tgc ttg aaa aag cac aaa      288
 Pro His Lys Asp Ser Leu Asn Leu Leu Pro Cys Leu Lys Lys His Lys
                  85                  90                  95

 att ctt acc act tct cag att tcc ccc acc tgg cat gac aat aaa aga      336
 Ile Leu Thr Thr Ser Gln Ile Ser Pro Thr Trp His Asp Asn Lys Arg
             100                 105                 110

 ccc aca aaa ctt agt cga tac gtt cca aag tag                          369
 Pro Thr Lys Leu Ser Arg Tyr Val Pro Lys 
         115                 120





      <210> 853
      <211> 357
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(357)

      <400> 853
  atg gca gtg gtc ctg gtt ata gta gta gag gcg ggt atg gtg gtg gtg      48
  Met Ala Val Val Leu Val Ile Val Val Glu Ala Gly Met Val Val Val
    1               5                  10                  15

 gac cag gat atg gaa acc aag gtg gtg gat atg gtg gcg gtg ttg gag       96
 Asp Gln Asp Met Glu Thr Lys Val Val Asp Met Val Ala Val Leu Glu
              20                  25                  30

 gat atg atg gtt aca atg aag gag gaa att ttg acg gta gta act atg      144
 Asp Met Met Val Thr Met Lys Glu Glu Ile Leu Thr Val Val Thr Met
          35                  40                  45

 gtg gtg tat ttc aga aac cga ggt cct cat ttg tta aaa gac aaa gag      192
 Val Val Tyr Phe Arg Asn Arg Gly Pro His Leu Leu Lys Asp Lys Glu
      50                  55                  60

 aac tca tcc ttg tcc aag cca aca gtg gac ata gaa gag cat gag cac      240
 Asn Ser Ser Leu Ser Lys Pro Thr Val Asp Ile Glu Glu His Glu His
  65                  70                  75                  80

 act tgg cca aag tgc atc cta gga gga ggc cca gca tac aca aag gcc      288
 Thr Trp Pro Lys Cys Ile Leu Gly Gly Gly Pro Ala Tyr Thr Lys Ala
                  85                  90                  95

 ctg aag cca gag ctc acc tgg tat ttg cag gaa gag caa ggc ctc cag      336
 Leu Lys Pro Glu Leu Thr Trp Tyr Leu Gln Glu Glu Gln Gly Leu Gln
             100                 105                 110

 agt cag gag tgg aat ggg tag                                          357
 Ser Gln Glu Trp Asn Gly 
         115





      <210> 854
      <211> 687
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(687)

      <400> 854
  atg gcc agt tgc ctg cag ctt ctg cta tgt ttc tca ggt gtc tcg tgg      48
  Met Ala Ser Cys Leu Gln Leu Leu Leu Cys Phe Ser Gly Val Ser Trp
    1               5                  10                  15

 ctg gcc tgt ctc ggg tgt ctg ggt ggc acc ttc tcc tcc tgc cac ctt       96
 Leu Ala Cys Leu Gly Cys Leu Gly Gly Thr Phe Ser Ser Cys His Leu
              20                  25                  30

 cct tct ctg cag att ttg caa cca agc aag aaa gac aca gaa gag aag      144
 Pro Ser Leu Gln Ile Leu Gln Pro Ser Lys Lys Asp Thr Glu Glu Lys
          35                  40                  45

 agc ctg aga tgg aag gtg gat gga gct aaa ggc ata gtc aag gtt aat      192
 Ser Leu Arg Trp Lys Val Asp Gly Ala Lys Gly Ile Val Lys Val Asn
      50                  55                  60

 gtt cct ttt tct tat cca tcc tct ccc aaa tca aaa gcc gaa ctc att      240
 Val Pro Phe Ser Tyr Pro Ser Ser Pro Lys Ser Lys Ala Glu Leu Ile
  65                  70                  75                  80

 gcc tta act cag ggc ctc act ctt cca aag gga ctg cat atc aat att      288
 Ala Leu Thr Gln Gly Leu Thr Leu Pro Lys Gly Leu His Ile Asn Ile
                  85                  90                  95

 tat act gac tct aaa tat gcc ttc cac atc ctg cac cac cat tct gtt      336
 Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Leu His His His Ser Val
             100                 105                 110

 ata tgg gct gag aga ggt ttc ctc act aca caa ggg tcc tcc atc att      384
 Ile Trp Ala Glu Arg Gly Phe Leu Thr Thr Gln Gly Ser Ser Ile Ile
         115                 120                 125

 aat gcc tct tta ata aaa act ctt ctc aag gca gct tta ttt cca aag      432
 Asn Ala Ser Leu Ile Lys Thr Leu Leu Lys Ala Ala Leu Phe Pro Lys
     130                 135                 140

 gaa gct gga gtc att cac tgc aag ggc cat caa aag gca tcg gat gcc      480
 Glu Ala Gly Val Ile His Cys Lys Gly His Gln Lys Ala Ser Asp Ala
 145                 150                 155                 160

 att gct cag gga aac act tat gct gat aag tct gat aac gga ctg gcc      528
 Ile Ala Gln Gly Asn Thr Tyr Ala Asp Lys Ser Asp Asn Gly Leu Ala
                 165                 170                 175

 ttt act agt caa atc acc caa gca gtt tct cag gct ctt gtt att cag      576
 Phe Thr Ser Gln Ile Thr Gln Ala Val Ser Gln Ala Leu Val Ile Gln
             180                 185                 190

 tgg aaa ctt cat atc cct tac cat cct cag tct tca gga aag aca ggt      624
 Trp Lys Leu His Ile Pro Tyr His Pro Gln Ser Ser Gly Lys Thr Gly
         195                 200                 205

 cca gtg aaa cct ccc cag aca ttt cac atc agc aag ctg ccg ccc tcc      672
 Pro Val Lys Pro Pro Gln Thr Phe His Ile Ser Lys Leu Pro Pro Ser
     210                 215                 220

 tcc aca ctt act taa                                                  687
 Ser Thr Leu Thr 
 225





      <210> 855
      <211> 210
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(210)

      <400> 855
  atg gcc tgg ggt gct ttc ctt gtg gat gtt ctg cag ttt cta agc aat      48
  Met Ala Trp Gly Ala Phe Leu Val Asp Val Leu Gln Phe Leu Ser Asn
    1               5                  10                  15

 tct gct gca gaa gca cta ctg ggg gac acc ccc tct tca ggg atc tac       96
 Ser Ala Ala Glu Ala Leu Leu Gly Asp Thr Pro Ser Ser Gly Ile Tyr
              20                  25                  30

 ttc ccc gat agc cag ttc agc gtg gat act cat gcc gat gag cct aag      144
 Phe Pro Asp Ser Gln Phe Ser Val Asp Thr His Ala Asp Glu Pro Lys
          35                  40                  45

 aat gtt tgc ctg tca gag ata aac act gca ttt ctg cct gct gca cac      192
 Asn Val Cys Leu Ser Glu Ile Asn Thr Ala Phe Leu Pro Ala Ala His
      50                  55                  60

 aga gtt gct gga acc tga                                              210
 Arg Val Ala Gly Thr 
  65





      <210> 856
      <211> 708
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(708)

      <400> 856
  atg cct tgt ggt ttg agt gcc ttg atc atg tgc cct aag ggg atg gtg      48
  Met Pro Cys Gly Leu Ser Ala Leu Ile Met Cys Pro Lys Gly Met Val
    1               5                  10                  15

 gcg gtg gtg gtg gcc gtg gat gac gga gac tct cag gcc ttg gca gtt       96
 Ala Val Val Val Ala Val Asp Asp Gly Asp Ser Gln Ala Leu Ala Val
              20                  25                  30

 ccc ctc aca ctt cgg gtt cct cgg gga gga ggg gct gga acc cta gcc      144
 Pro Leu Thr Leu Arg Val Pro Arg Gly Gly Gly Ala Gly Thr Leu Ala
          35                  40                  45

 cat cgt cag gac aaa gat gct cag gct gct ctt ggc tct caa ctt att      192
 His Arg Gln Asp Lys Asp Ala Gln Ala Ala Leu Gly Ser Gln Leu Ile
      50                  55                  60

 ccc ttc aat tca agt aac aga acc cag ctg aga aag tct gta cgg agt      240
 Pro Phe Asn Ser Ser Asn Arg Thr Gln Leu Arg Lys Ser Val Arg Ser
  65                  70                  75                  80

 cgg act gca gga aag caa gcg gtc ccc cag gac aac ggc cag ccc aag      288
 Arg Thr Ala Gly Lys Gln Ala Val Pro Gln Asp Asn Gly Gln Pro Lys
                  85                  90                  95

 gag act gta tca atg ctg cca tca agg gag cgc acc cct gac agg gga      336
 Glu Thr Val Ser Met Leu Pro Ser Arg Glu Arg Thr Pro Asp Arg Gly
             100                 105                 110

 ggc agc tgc aga ctg ccg cag ctt atg aga caa cca cgt agg aat tct      384
 Gly Ser Cys Arg Leu Pro Gln Leu Met Arg Gln Pro Arg Arg Asn Ser
         115                 120                 125

 ccg tct cat ccc ctt acc tct cat ccc tct ccc tgc cca gcc cca ggt      432
 Pro Ser His Pro Leu Thr Ser His Pro Ser Pro Cys Pro Ala Pro Gly
     130                 135                 140

 gtg tgg aag cac caa gca tca cca tgc ttt aga ggc acc gta agt gta      480
 Val Trp Lys His Gln Ala Ser Pro Cys Phe Arg Gly Thr Val Ser Val
 145                 150                 155                 160

 tta gtc cgt ttt cat gct gct gat aaa cac ata cct gag act ggg aag      528
 Leu Val Arg Phe His Ala Ala Asp Lys His Ile Pro Glu Thr Gly Lys
                 165                 170                 175

 aaa aag agg ttt aat gga ctt aca gtt cca cat ggc tgg gga gga ctc      576
 Lys Lys Arg Phe Asn Gly Leu Thr Val Pro His Gly Trp Gly Gly Leu
             180                 185                 190

 aca atc atg gca gaa ggt gat gag gag caa gtc aca tct tac atg gat      624
 Thr Ile Met Ala Glu Gly Asp Glu Glu Gln Val Thr Ser Tyr Met Asp
         195                 200                 205

 ggc agc agg caa aaa gag agc ttg tgc agg gaa act ccc att ttt aaa      672
 Gly Ser Arg Gln Lys Glu Ser Leu Cys Arg Glu Thr Pro Ile Phe Lys
     210                 215                 220

 acc atc aga tct cat gag act tat tca cta tta tga                      708
 Thr Ile Arg Ser His Glu Thr Tyr Ser Leu Leu 
 225                 230                 235





      <210> 857
      <211> 786
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(786)

      <400> 857
  atg gct ctg ttg gtg ctc gct ggg ctt gct ttg gct ggc aca gct cct      48
  Met Ala Leu Leu Val Leu Ala Gly Leu Ala Leu Ala Gly Thr Ala Pro
    1               5                  10                  15

 aca gct cag caa acc gcc ttc agc tct gat ggg gct tct acc cca tgc       96
 Thr Ala Gln Gln Thr Ala Phe Ser Ser Asp Gly Ala Ser Thr Pro Cys
              20                  25                  30

 aag ctg aca gtg aat ttc cga agg gca gat ttt ctc cct aat gtc cta      144
 Lys Leu Thr Val Asn Phe Arg Arg Ala Asp Phe Leu Pro Asn Val Leu
          35                  40                  45

 gag gac cct gct ttc tcg gct gtg att cac gac aaa ctc cag gtc ccc      192
 Glu Asp Pro Ala Phe Ser Ala Val Ile His Asp Lys Leu Gln Val Pro
      50                  55                  60

 aac acc atc cgg aag gca tgg aac gac cgg gac aac cgc tgt gac att      240
 Asn Thr Ile Arg Lys Ala Trp Asn Asp Arg Asp Asn Arg Cys Asp Ile
  65                  70                  75                  80

 tgc gcc act cac ctg aac cag ttg aag cag gag gcc atc cag atg gtg      288
 Cys Ala Thr His Leu Asn Gln Leu Lys Gln Glu Ala Ile Gln Met Val
                  85                  90                  95

 ctg acg ttg gag cag gca gcc ggc agt gag cac tac gac gcc tcg ccc      336
 Leu Thr Leu Glu Gln Ala Ala Gly Ser Glu His Tyr Asp Ala Ser Pro
             100                 105                 110

 tgc tcc ccg cca ccg ctc tcc aac atc ccc acc ctg gtg ggg tcc cgg      384
 Cys Ser Pro Pro Pro Leu Ser Asn Ile Pro Thr Leu Val Gly Ser Arg
         115                 120                 125

 cac gtg ggt ggg ctc cag cag ccc aga gac tgg gcc ttt gtg ccc gcc      432
 His Val Gly Gly Leu Gln Gln Pro Arg Asp Trp Ala Phe Val Pro Ala
     130                 135                 140

 ccc tgt gcc acc tcc aac tac aca ggc ttc gcc aac aag cac ggc agc      480
 Pro Cys Ala Thr Ser Asn Tyr Thr Gly Phe Ala Asn Lys His Gly Ser
 145                 150                 155                 160

 aaa ccc agc agc ctt ggg gtc agc aat ggg gcg gaa aag aag agc ggg      528
 Lys Pro Ser Ser Leu Gly Val Ser Asn Gly Ala Glu Lys Lys Ser Gly
                 165                 170                 175

 tcc cca acc cac cag gcc aag gtc agc ctc cag atg gcc acc agt cca      576
 Ser Pro Thr His Gln Ala Lys Val Ser Leu Gln Met Ala Thr Ser Pro
             180                 185                 190

 agc aat ggg aac atc ctc aat tcg gtg gcc atc cag gct cac cag tac      624
 Ser Asn Gly Asn Ile Leu Asn Ser Val Ala Ile Gln Ala His Gln Tyr
         195                 200                 205

 ctg gat ggc acc tgg tcc ctg tcg aga acc aac ggg gtc acc ctg tac      672
 Leu Asp Gly Thr Trp Ser Leu Ser Arg Thr Asn Gly Val Thr Leu Tyr
     210                 215                 220

 cca tac cag ggg tgt ggg aag cag cag aga gca ttg acc gtc act gga      720
 Pro Tyr Gln Gly Cys Gly Lys Gln Gln Arg Ala Leu Thr Val Thr Gly
 225                 230                 235                 240

 atg gag agg cgg cca cgg tca agg gtg tat tac tca gag aag ata gtt      768
 Met Glu Arg Arg Pro Arg Ser Arg Val Tyr Tyr Ser Glu Lys Ile Val
                 245                 250                 255

 ggt aca tac agc aaa tga                                              786
 Gly Thr Tyr Ser Lys 
             260





      <210> 858
      <211> 348
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(348)

      <400> 858
  atg aaa atg tcc ctg ctt cat act ggg cct ctc agc aaa ctt ctc ttg      48
  Met Lys Met Ser Leu Leu His Thr Gly Pro Leu Ser Lys Leu Leu Leu
    1               5                  10                  15

 ctg aca gga att att tcc ctc tat gat tgt att ttt aag agg cgc cta       96
 Leu Thr Gly Ile Ile Ser Leu Tyr Asp Cys Ile Phe Lys Arg Arg Leu
              20                  25                  30

 gat tat gat cag aag ttg cac cga gat gac aga gaa cat gca aaa agc      144
 Asp Tyr Asp Gln Lys Leu His Arg Asp Asp Arg Glu His Ala Lys Ser
          35                  40                  45

 ctg gga ctt cat gtt aac gaa gag gaa cag gag agg ccg gtt gga gtg      192
 Leu Gly Leu His Val Asn Glu Glu Glu Gln Glu Arg Pro Val Gly Val
      50                  55                  60

 ctg acg tct tct gtc tat ggg aag cgc atc aat cag ccc att gag ccc      240
 Leu Thr Ser Ser Val Tyr Gly Lys Arg Ile Asn Gln Pro Ile Glu Pro
  65                  70                  75                  80

 cta aac cgg gac ttt ggc cgt gcc aac cat gtg cag gct gac ttc tac      288
 Leu Asn Arg Asp Phe Gly Arg Ala Asn His Val Gln Ala Asp Phe Tyr
                  85                  90                  95

 agg aag aac gac atc ccc agc ctc aag gaa ccc ggc ttt ggg cac att      336
 Arg Lys Asn Asp Ile Pro Ser Leu Lys Glu Pro Gly Phe Gly His Ile
             100                 105                 110

 gct cca tcc tga                                                      348
 Ala Pro Ser 
         115





      <210> 859
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 859
  atg ccg cgc atg cgc ctc ttt cat ctt ccc atc atg gcc gcc gcc tgt      48
  Met Pro Arg Met Arg Leu Phe His Leu Pro Ile Met Ala Ala Ala Cys
    1               5                  10                  15

 gcg cct ctg ctg agt cgg gtt gtg gtg gct ggg cag agc cag agt ccg       96
 Ala Pro Leu Leu Ser Arg Val Val Val Ala Gly Gln Ser Gln Ser Pro
              20                  25                  30

 cct cgg ggt gat gga gct gtg gcc atc acc ggt ctg aca gtg gac cag      144
 Pro Arg Gly Asp Gly Ala Val Ala Ile Thr Gly Leu Thr Val Asp Gln
          35                  40                  45

 tat ggc atg ctg tat aag gtg gct gtg ccg cct gcc acc ttc tca cca      192
 Tyr Gly Met Leu Tyr Lys Val Ala Val Pro Pro Ala Thr Phe Ser Pro
      50                  55                  60

 act gga ctc cca tct gtg tga                                          213
 Thr Gly Leu Pro Ser Val 
  65                  70





      <210> 860
      <211> 555
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(555)

      <400> 860
  atg ctg ggc acc gtg ctg ctg ctg gcc ctg ctc cca ggg atc acc acc      48
  Met Leu Gly Thr Val Leu Leu Leu Ala Leu Leu Pro Gly Ile Thr Thr
    1               5                  10                  15

 tta ccc agc ggg cca cct gca ggc tcc ggg ggg cac ctg gcc tgg gtc       96
 Leu Pro Ser Gly Pro Pro Ala Gly Ser Gly Gly His Leu Ala Trp Val
              20                  25                  30

 ccc ggt gca ctc acc cgg tcc ttc cca gtc ctg gac ctc aac gtg gac      144
 Pro Gly Ala Leu Thr Arg Ser Phe Pro Val Leu Asp Leu Asn Val Asp
          35                  40                  45

 tgg gcc agg tgt gga cca cct tcc ctg aag gcc atc ctg tgc ggc cag      192
 Trp Ala Arg Cys Gly Pro Pro Ser Leu Lys Ala Ile Leu Cys Gly Gln
      50                  55                  60

 ggc ccc gca gac ccc tcc aca tcc cct gag gtc ttc aac tca ccc caa      240
 Gly Pro Ala Asp Pro Ser Thr Ser Pro Glu Val Phe Asn Ser Pro Gln
  65                  70                  75                  80

 gct gtg gcc ccc gga gac ccc aga gca gca gcc cca gcc cag ctc ccc      288
 Ala Val Ala Pro Gly Asp Pro Arg Ala Ala Ala Pro Ala Gln Leu Pro
                  85                  90                  95

 agt gcc cga ggg cgg ttg ggg ccc cac cac aag cag cta atc gtg act      336
 Ser Ala Arg Gly Arg Leu Gly Pro His His Lys Gln Leu Ile Val Thr
             100                 105                 110

 ttg gta aaa gtt tct gaa gtc cta ggt ggc cgt cca ggt ccc agg tct      384
 Leu Val Lys Val Ser Glu Val Leu Gly Gly Arg Pro Gly Pro Arg Ser
         115                 120                 125

 ccc ctg gca ggc agc tgg gtg gcc aag tgg gga ggg ggc ctg tgc cat      432
 Pro Leu Ala Gly Ser Trp Val Ala Lys Trp Gly Gly Gly Leu Cys His
     130                 135                 140

 gcc cct ggc ccc ctg tgg ggc tgg ccg ccg cca agc agc tac ctg aag      480
 Ala Pro Gly Pro Leu Trp Gly Trp Pro Pro Pro Ser Ser Tyr Leu Lys
 145                 150                 155                 160

 aag ggc aga agc gtg ctc aca atc tcc aac agc cac ccc gcc aaa tcc      528
 Lys Gly Arg Ser Val Leu Thr Ile Ser Asn Ser His Pro Ala Lys Ser
                 165                 170                 175

 aca ggg ctg gct gtc ccc tca ggc tag                                  555
 Thr Gly Leu Ala Val Pro Ser Gly 
             180





      <210> 861
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 861
  atg agc aga tgc ttg cca gct cta atc aat aag ctg tat gcc ttg tcc      48
  Met Ser Arg Cys Leu Pro Ala Leu Ile Asn Lys Leu Tyr Ala Leu Ser
    1               5                  10                  15

 ttc tcc ctg tat ctg agg atc ata tac tac ttt att gtc cat gtc ctc       96
 Phe Ser Leu Tyr Leu Arg Ile Ile Tyr Tyr Phe Ile Val His Val Leu
              20                  25                  30

 atg caa cag aca caa ggg att act gga aag aaa aag att aca gga tca      144
 Met Gln Gln Thr Gln Gly Ile Thr Gly Lys Lys Lys Ile Thr Gly Ser
          35                  40                  45

 gat ttg tcc ttc ccc cac tcc aaa agg cca aaa cat ttc aac agc tat      192
 Asp Leu Ser Phe Pro His Ser Lys Arg Pro Lys His Phe Asn Ser Tyr
      50                  55                  60

 gtt ttc aac tac agt tta gat agt aca gtt gct gga tat ttg ttt ttg      240
 Val Phe Asn Tyr Ser Leu Asp Ser Thr Val Ala Gly Tyr Leu Phe Leu
  65                  70                  75                  80

 gat agc aga ggc aaa gag aaa tgt ttt tac ctt acc aat gcc aca tct      288
 Asp Ser Arg Gly Lys Glu Lys Cys Phe Tyr Leu Thr Asn Ala Thr Ser
                  85                  90                  95

 tgt cag cat ttc agc agt cac act acc tac tcc acc aac acc tac tat      336
 Cys Gln His Phe Ser Ser His Thr Thr Tyr Ser Thr Asn Thr Tyr Tyr
             100                 105                 110

 tgc tac ggc aaa ggt gag aag ctg aag cgg aaa gtt tca caa ctt gcc      384
 Cys Tyr Gly Lys Gly Glu Lys Leu Lys Arg Lys Val Ser Gln Leu Ala
         115                 120                 125

 aaa gga ctt cgg cac tcg aga cct gtg gat gcc gcg ttg ctg tgg cct      432
 Lys Gly Leu Arg His Ser Arg Pro Val Asp Ala Ala Leu Leu Trp Pro
     130                 135                 140

 gcg ggg gtg atc atg aag cca ggt gct act ggc gag tcc gat ttg gcc      480
 Ala Gly Val Ile Met Lys Pro Gly Ala Thr Gly Glu Ser Asp Leu Ala
 145                 150                 155                 160

 gaa gtg ctg ccc cag cac aag ttc gac agc aag tcc ctg gag gcc tac      528
 Glu Val Leu Pro Gln His Lys Phe Asp Ser Lys Ser Leu Glu Ala Tyr
                 165                 170                 175

 cta aac cag cac ttg tct ggc ttt ggg gcc gaa cgt gag gct acg ctg      576
 Leu Asn Gln His Leu Ser Gly Phe Gly Ala Glu Arg Glu Ala Thr Leu
             180                 185                 190

 acc att gcc cag tac agt cag tgg acg cac cct aca ggc atg agc tgc      624
 Thr Ile Ala Gln Tyr Ser Gln Trp Thr His Pro Thr Gly Met Ser Cys
         195                 200                 205

 tat tgc cgg ccc tcc gaa ttc gat gct ggg ggc ttc cca att gga ggg      672
 Tyr Cys Arg Pro Ser Glu Phe Asp Ala Gly Gly Phe Pro Ile Gly Gly
     210                 215                 220

 cgg taa                                                              678
 Arg 
 225





      <210> 862
      <211> 1245
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1245)

      <400> 862
  atg ccg aga tcg tgc tgc agc cgc tcg ggg gcc ctg ttg ctg gcc ttg      48
  Met Pro Arg Ser Cys Cys Ser Arg Ser Gly Ala Leu Leu Leu Ala Leu
    1               5                  10                  15

 ctg ctt cag gcc tcc atg gaa gtg cgt ggc tgg tgc ctg gag agc agc       96
 Leu Leu Gln Ala Ser Met Glu Val Arg Gly Trp Cys Leu Glu Ser Ser
              20                  25                  30

 cag tgt cag gac ctc acc acg gaa agc aac ctg ctg cga gtg cct gcc      144
 Gln Cys Gln Asp Leu Thr Thr Glu Ser Asn Leu Leu Arg Val Pro Ala
          35                  40                  45

 gag gag atc acc tat gag aca ctg aag aaa gcc att gct tgg ccc cct      192
 Glu Glu Ile Thr Tyr Glu Thr Leu Lys Lys Ala Ile Ala Trp Pro Pro
      50                  55                  60

 cat gtc aac ccc tgg aag att cag gaa cca cat agg gtg ggc tct cta      240
 His Val Asn Pro Trp Lys Ile Gln Glu Pro His Arg Val Gly Ser Leu
  65                  70                  75                  80

 gga gct gcc cca aca ggg acc cac gga cag cgc tcc ctg acc agg cgt      288
 Gly Ala Ala Pro Thr Gly Thr His Gly Gln Arg Ser Leu Thr Arg Arg
                  85                  90                  95

 ggc gag gcc cct gag cca gta cga ggt gtg cag gta gca gtg ggc ggg      336
 Gly Glu Ala Pro Glu Pro Val Arg Gly Val Gln Val Ala Val Gly Gly
             100                 105                 110

 aag ggg aaa gga ccc gct atc agt tcc tgg cag cgg cag cag cag ccc      384
 Lys Gly Lys Gly Pro Ala Ile Ser Ser Trp Gln Arg Gln Gln Gln Pro
         115                 120                 125

 ctt cac agc gag ttc ctg aac att ctt ctt ccc cca caa ctt ccc cca      432
 Leu His Ser Glu Phe Leu Asn Ile Leu Leu Pro Pro Gln Leu Pro Pro
     130                 135                 140

 gct tgt cag atg ccg cgc tgc gag ctg ttc agc atc ccc agc cca ctt      480
 Ala Cys Gln Met Pro Arg Cys Glu Leu Phe Ser Ile Pro Ser Pro Leu
 145                 150                 155                 160

 ggt gca gaa cac gca ccc ggc ccg gga atg cag cat gac ttc gtc gct      528
 Gly Ala Glu His Ala Pro Gly Pro Gly Met Gln His Asp Phe Val Ala
                 165                 170                 175

 gct tct ctc act gat acc tct tct gca tcc atg ccg gtc aac ggg cct      576
 Ala Ser Leu Thr Asp Thr Ser Ser Ala Ser Met Pro Val Asn Gly Pro
             180                 185                 190

 gag aac tta ctt cag gcc tcc tct caa aag aag ttt ctg gtt ctg gct      624
 Glu Asn Leu Leu Gln Ala Ser Ser Gln Lys Lys Phe Leu Val Leu Ala
         195                 200                 205

 tgg tgg cct ttt gca gac act gtc tca tcg ttt ttc aaa aac agc aag      672
 Trp Trp Pro Phe Ala Asp Thr Val Ser Ser Phe Phe Lys Asn Ser Lys
     210                 215                 220

 ttg ggg gcc cag ttt gtg aag ttt gcc aac atc gag gag gac acc ccg      720
 Leu Gly Ala Gln Phe Val Lys Phe Ala Asn Ile Glu Glu Asp Thr Pro
 225                 230                 235                 240

 tcc tat cac cgg agc tat gac ttc ttt gtg tcc cga ttc agt gaa atg      768
 Ser Tyr His Arg Ser Tyr Asp Phe Phe Val Ser Arg Phe Ser Glu Met
                 245                 250                 255

 tgc cac tcg agc cat gat gac tta gaa atc aag acc aag ctc aat cag      816
 Cys His Ser Ser His Asp Asp Leu Glu Ile Lys Thr Lys Leu Asn Gln
             260                 265                 270

 tac ttc cac ccc agc ctc ctg agt atc tgt gac tac agg tac gtg tgc      864
 Tyr Phe His Pro Ser Leu Leu Ser Ile Cys Asp Tyr Arg Tyr Val Cys
         275                 280                 285

 att gct atg gag gct ttg gac cag ctg ctc atg gcc tgc cac tgc cag      912
 Ile Ala Met Glu Ala Leu Asp Gln Leu Leu Met Ala Cys His Cys Gln
     290                 295                 300

 agc atc aac ctc ttc gtg gag agc ttc ctc aag atg gtg gcc aag ctg      960
 Ser Ile Asn Leu Phe Val Glu Ser Phe Leu Lys Met Val Ala Lys Leu
 305                 310                 315                 320

 ctg gag tca gag aaa ccc aac ctg cag atc ctc ggc acc aac tcg gac     1008
 Leu Glu Ser Glu Lys Pro Asn Leu Gln Ile Leu Gly Thr Asn Ser Asp
                 325                 330                 335

 aga aga ttc ggc aga act aag cag gcg tca gag gag ttg gtg ggt gtg     1056
 Arg Arg Phe Gly Arg Thr Lys Gln Ala Ser Glu Glu Leu Val Gly Val
             340                 345                 350

 agt gcc cct gtc cct gca ctt cgg gtg gct gct ggt cct ccg ggt cct     1104
 Ser Ala Pro Val Pro Ala Leu Arg Val Ala Ala Gly Pro Pro Gly Pro
         355                 360                 365

 gct gtg tgg tta gac ggc ttc cgg gca gcc tgg ccc cag aga ctt ctt     1152
 Ala Val Trp Leu Asp Gly Phe Arg Ala Ala Trp Pro Gln Arg Leu Leu
     370                 375                 380

 gct att gaa cat cct att gga aag caa act ttc caa gag agc acc cgg     1200
 Ala Ile Glu His Pro Ile Gly Lys Gln Thr Phe Gln Glu Ser Thr Arg
 385                 390                 395                 400

 gac ctg tta gct ttt gaa aca ggc ctg ggt gtg att gac tgg tag         1245
 Asp Leu Leu Ala Phe Glu Thr Gly Leu Gly Val Ile Asp Trp 
                 405                 410





      <210> 863
      <211> 372
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(372)

      <400> 863
  atg aca gaa tct cgg ctg gtg gac aga tac tac agc ttt ctc ctc ctc      48
  Met Thr Glu Ser Arg Leu Val Asp Arg Tyr Tyr Ser Phe Leu Leu Leu
    1               5                  10                  15

 ctt gtg ttc gtg ttc agt ctc tgt gga gac ttt ctt ttc cat tca aat       96
 Leu Val Phe Val Phe Ser Leu Cys Gly Asp Phe Leu Phe His Ser Asn
              20                  25                  30

 gac agt gcg cac tta tct ggt tta cac aat gat acc att ttg aaa gtt      144
 Asp Ser Ala His Leu Ser Gly Leu His Asn Asp Thr Ile Leu Lys Val
          35                  40                  45

 gga agc ctc aaa ctg aga cga cag tgc aga aca aaa caa aaa tta aac      192
 Gly Ser Leu Lys Leu Arg Arg Gln Cys Arg Thr Lys Gln Lys Leu Asn
      50                  55                  60

 cac aaa gaa atg gaa gac ctg aac aaa cca ata atg agt aat gag atc      240
 His Lys Glu Met Glu Asp Leu Asn Lys Pro Ile Met Ser Asn Glu Ile
  65                  70                  75                  80

 aaa gcc atg ata aaa agt ttt cca cca aag aaa agc cca gaa tct gat      288
 Lys Ala Met Ile Lys Ser Phe Pro Pro Lys Lys Ser Pro Glu Ser Asp
                  85                  90                  95

 ggc ttc act gtt gaa ttc cag caa ata tat gaa gaa gaa gta ata cca      336
 Gly Phe Thr Val Glu Phe Gln Gln Ile Tyr Glu Glu Glu Val Ile Pro
             100                 105                 110

 att ctg ttc caa cta ttc aaa aaa att gaa gag tga                      372
 Ile Leu Phe Gln Leu Phe Lys Lys Ile Glu Glu 
         115                 120





      <210> 864
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 864
  atg gca aaa ctg gaa gcg ttt aca atg ttc ccc agt gta ctg ctg gca      48
  Met Ala Lys Leu Glu Ala Phe Thr Met Phe Pro Ser Val Leu Leu Ala
    1               5                  10                  15

 ttg ttg caa atg aac aag ggc atg att ctt gac aag aga att aat gtg       96
 Leu Leu Gln Met Asn Lys Gly Met Ile Leu Asp Lys Arg Ile Asn Val
              20                  25                  30

 ggt att gag cac att aag cac tct ggg agt caa gat agc ttc ctg aaa      144
 Gly Ile Glu His Ile Lys His Ser Gly Ser Gln Asp Ser Phe Leu Lys
          35                  40                  45

 cac gtg aag gaa aat gat cag aaa aag aag ccc aag aga agg ctt gtc      192
 His Val Lys Glu Asn Asp Gln Lys Lys Lys Pro Lys Arg Arg Leu Val
      50                  55                  60

 tca gtc tgc tga                                                      204
 Ser Val Cys 
  65





      <210> 865
      <211> 450
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(450)

      <400> 865
  atg agg cgt gtc att cat atc ctg ctc tcc ccg gcc ttc ctc caa acc      48
  Met Arg Arg Val Ile His Ile Leu Leu Ser Pro Ala Phe Leu Gln Thr
    1               5                  10                  15

 cgt tct gac aag cag gga agg gac acg atg tac ttc ctg gga agg aga       96
 Arg Ser Asp Lys Gln Gly Arg Asp Thr Met Tyr Phe Leu Gly Arg Arg
              20                  25                  30

 gaa gat gac aac ctt ggt ccc ctg gaa gtt cag cac ttt cca cag act      144
 Glu Asp Asp Asn Leu Gly Pro Leu Glu Val Gln His Phe Pro Gln Thr
          35                  40                  45

 cta ctg cag gcc tac tct gtg cta ggc cct gtg ctg agc ccg gca gaa      192
 Leu Leu Gln Ala Tyr Ser Val Leu Gly Pro Val Leu Ser Pro Ala Glu
      50                  55                  60

 tgg gag act cct gtc tgg ggt cag gaa gag ccc tca gcc ctg aat gga      240
 Trp Glu Thr Pro Val Trp Gly Gln Glu Glu Pro Ser Ala Leu Asn Gly
  65                  70                  75                  80

 cgt ggc cgc acc cat ccc aga ccc tca cct atg ttt gaa ggc att gtt      288
 Arg Gly Arg Thr His Pro Arg Pro Ser Pro Met Phe Glu Gly Ile Val
                  85                  90                  95

 cac gat ggc ttt gag cac cag acg gtc gcc gac ctg gga cgg gcc tcg      336
 His Asp Gly Phe Glu His Gln Thr Val Ala Asp Leu Gly Arg Ala Ser
             100                 105                 110

 gaa gtg gaa cat ttc aat ggc ctt cag cgt agg gag ctg cag cag gtc      384
 Glu Val Glu His Phe Asn Gly Leu Gln Arg Arg Glu Leu Gln Gln Val
         115                 120                 125

 aag aga cag tac cca gtg aag ctg agt ggc cag cca gaa ggc cca gtg      432
 Lys Arg Gln Tyr Pro Val Lys Leu Ser Gly Gln Pro Glu Gly Pro Val
     130                 135                 140

 cca ggc aaa ggc act tga                                              450
 Pro Gly Lys Gly Thr 
 145





      <210> 866
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 866
  atg gca aca att gtc tgc cta cta aca atg ttc act caa ggc cta aga      48
  Met Ala Thr Ile Val Cys Leu Leu Thr Met Phe Thr Gln Gly Leu Arg
    1               5                  10                  15

 gtg ctt cag tca tca gat att gag tcc agg tgg caa gct cct ccc tgg       96
 Val Leu Gln Ser Ser Asp Ile Glu Ser Arg Trp Gln Ala Pro Pro Trp
              20                  25                  30

 ccc agg gtg aga caa gac atg ctg tcc agg agg cac tac ctg gaa ctg      144
 Pro Arg Val Arg Gln Asp Met Leu Ser Arg Arg His Tyr Leu Glu Leu
          35                  40                  45

 gga acc tca gga atc ttc ctg gtg ctc cat tat act atg act gag cta      192
 Gly Thr Ser Gly Ile Phe Leu Val Leu His Tyr Thr Met Thr Glu Leu
      50                  55                  60

 aca ccc aag ctg aaa gtg ggc tcc tcg ctg tct caa gta ccg gat tta      240
 Thr Pro Lys Leu Lys Val Gly Ser Ser Leu Ser Gln Val Pro Asp Leu
  65                  70                  75                  80

 ctt act ttg acc att tgc acg tgt tac aat cgg gtg aaa gaa cat ggt      288
 Leu Thr Leu Thr Ile Cys Thr Cys Tyr Asn Arg Val Lys Glu His Gly
                  85                  90                  95

 gtt gcg aaa aga aag agc agt tac aca gta gaa cag ttg gaa cag gtg      336
 Val Ala Lys Arg Lys Ser Ser Tyr Thr Val Glu Gln Leu Glu Gln Val
             100                 105                 110

 ttt gct cag gca gga tgg gat gct cag ccc tgc cag act gta ctt ctt      384
 Phe Ala Gln Ala Gly Trp Asp Ala Gln Pro Cys Gln Thr Val Leu Leu
         115                 120                 125

 aac agc agt agc ttg tac cag gag ctg gag tca gat ggc ggc acc atg      432
 Asn Ser Ser Ser Leu Tyr Gln Glu Leu Glu Ser Asp Gly Gly Thr Met
     130                 135                 140

 gag gac tat tca ttc aca gga gta ctg gga acc caa agt cag gat ctc      480
 Glu Asp Tyr Ser Phe Thr Gly Val Leu Gly Thr Gln Ser Gln Asp Leu
 145                 150                 155                 160

 cat ggc tat ccg aca gat cag gaa tca caa aga gaa aat taa              522
 His Gly Tyr Pro Thr Asp Gln Glu Ser Gln Arg Glu Asn 
                 165                 170





      <210> 867
      <211> 336
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(336)

      <400> 867
  atg ctc tcc acc tgc aag gtc ctg gca gcg gcg cac gtc acc gcg caa      48
  Met Leu Ser Thr Cys Lys Val Leu Ala Ala Ala His Val Thr Ala Gln
    1               5                  10                  15

 gtc ctg gca gct gcg cgc ttc act cta ctg cct gcg gac cgg ccc aag       96
 Val Leu Ala Ala Ala Arg Phe Thr Leu Leu Pro Ala Asp Arg Pro Lys
              20                  25                  30

 tcc tcg ccc gcg tgg gct ggg gac ggg gcg gga aat ggc ctg cgt ggg      144
 Ser Ser Pro Ala Trp Ala Gly Asp Gly Ala Gly Asn Gly Leu Arg Gly
          35                  40                  45

 cct cct ccg ctg ctc tca tcc tgc acg gac ccg ccc tgc atg ggc acg      192
 Pro Pro Pro Leu Leu Ser Ser Cys Thr Asp Pro Pro Cys Met Gly Thr
      50                  55                  60

 ccc tgc gtg cac ggg cct gcc cgc gtg gac gtg ccc tgc gtg cac cct      240
 Pro Cys Val His Gly Pro Ala Arg Val Asp Val Pro Cys Val His Pro
  65                  70                  75                  80

 tcc ttc agg gac ccg ccc ttg aac ggc cct ccg gac gtg gac act cgt      288
 Ser Phe Arg Asp Pro Pro Leu Asn Gly Pro Pro Asp Val Asp Thr Arg
                  85                  90                  95

 ata cgc cca ccc tgc gtg gga tct ccc tgc gtg gac cca tcc cgc tga      336
 Ile Arg Pro Pro Cys Val Gly Ser Pro Cys Val Asp Pro Ser Arg 
             100                 105                 110





      <210> 868
      <211> 411
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(411)

      <400> 868
  atg ctc atg ctg gtc ctt gca cta ctc tca ggg cag caa ggt gca gac      48
  Met Leu Met Leu Val Leu Ala Leu Leu Ser Gly Gln Gln Gly Ala Asp
    1               5                  10                  15

 act ctg agc tca gct ttt gtg aaa aat cag tac acg aat aca ccg gag       96
 Thr Leu Ser Ser Ala Phe Val Lys Asn Gln Tyr Thr Asn Thr Pro Glu
              20                  25                  30

 tgt aat gta act aag aga cca cca gac caa gaa agc aag gca tcc tcc      144
 Cys Asn Val Thr Lys Arg Pro Pro Asp Gln Glu Ser Lys Ala Ser Ser
          35                  40                  45

 cag gag aat gag ggt gcc ctg gct ggt ctg ccc tca ctc caa ccc gca      192
 Gln Glu Asn Glu Gly Ala Leu Ala Gly Leu Pro Ser Leu Gln Pro Ala
      50                  55                  60

 gac ctg cgg agc atc cag ggg gcc gat act cag agc cct cct ggt ctg      240
 Asp Leu Arg Ser Ile Gln Gly Ala Asp Thr Gln Ser Pro Pro Gly Leu
  65                  70                  75                  80

 gac cgg gcc cac aca gag ttg gag aga tca ggc cat tct gca atg ttc      288
 Asp Arg Ala His Thr Glu Leu Glu Arg Ser Gly His Ser Ala Met Phe
                  85                  90                  95

 ctg gaa cac ctg gag agg gat gga ctg ccc ctg ctg gac ctg agg gtt      336
 Leu Glu His Leu Glu Arg Asp Gly Leu Pro Leu Leu Asp Leu Arg Val
             100                 105                 110

 agc agg gct cag atg act ggc agc atg ggc tcc gtg agc ctt tct ggc      384
 Ser Arg Ala Gln Met Thr Gly Ser Met Gly Ser Val Ser Leu Ser Gly
         115                 120                 125

 ttg ttc tcc tgg att ctt gca agt taa                                  411
 Leu Phe Ser Trp Ile Leu Ala Ser 
     130                 135





      <210> 869
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 869
  atg gcc tgc aag gcc tac gtg aca tgg tcc atg gct gcc ctt acc acc      48
  Met Ala Cys Lys Ala Tyr Val Thr Trp Ser Met Ala Ala Leu Thr Thr
    1               5                  10                  15

 tca ttt tct acc ctc tcc ttc act tct cag ctc cag cct cct tgc agc       96
 Ser Phe Ser Thr Leu Ser Phe Thr Ser Gln Leu Gln Pro Pro Cys Ser
              20                  25                  30

 act tta gaa atg tca acc ctg act cca gtg tct cca gct gag agg ctg      144
 Thr Leu Glu Met Ser Thr Leu Thr Pro Val Ser Pro Ala Glu Arg Leu
          35                  40                  45

 agc ttg cca gct cca ttt ctg act gct cat gga gca gaa tca gtg acc      192
 Ser Leu Pro Ala Pro Phe Leu Thr Ala His Gly Ala Glu Ser Val Thr
      50                  55                  60

 aag gag aaa agg gct gag tga                                          213
 Lys Glu Lys Arg Ala Glu 
  65                  70





      <210> 870
      <211> 357
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(357)

      <400> 870
  atg cag ctc ggc act ggg ctc ctg ctg gcc gcc gtc ctg agc ctg cag      48
  Met Gln Leu Gly Thr Gly Leu Leu Leu Ala Ala Val Leu Ser Leu Gln
    1               5                  10                  15

 ctg ggc tgc ttc ctg ggc aag gat gca acc agc tgg ctc cag ctg cag       96
 Leu Gly Cys Phe Leu Gly Lys Asp Ala Thr Ser Trp Leu Gln Leu Gln
              20                  25                  30

 ggc tgc cag gca ccc caa gct gca gcc gaa gcc ata tgg tgt cac cag      144
 Gly Cys Gln Ala Pro Gln Ala Ala Ala Glu Ala Ile Trp Cys His Gln
          35                  40                  45

 tgc acg ggc ttc gga ggg tgc tcc cat gga tcc aga tgc ctg agg gac      192
 Cys Thr Gly Phe Gly Gly Cys Ser His Gly Ser Arg Cys Leu Arg Asp
      50                  55                  60

 tcc acc cac tgt gtc acc act gcc acc cgg gtc ctc agc aac acc gag      240
 Ser Thr His Cys Val Thr Thr Ala Thr Arg Val Leu Ser Asn Thr Glu
  65                  70                  75                  80

 gat ttg cct ctg gtc acc aag atg tgc cac ata ggc tgc ccc gat atc      288
 Asp Leu Pro Leu Val Thr Lys Met Cys His Ile Gly Cys Pro Asp Ile
                  85                  90                  95

 ccc agc ctg ggc ctg ggc ccc tac gta tcc atc gct tgc tgc cag acc      336
 Pro Ser Leu Gly Leu Gly Pro Tyr Val Ser Ile Ala Cys Cys Gln Thr
             100                 105                 110

 agc ctc tgc aac cat gac tga                                          357
 Ser Leu Cys Asn His Asp 
         115





      <210> 871
      <211> 987
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(987)

      <400> 871
  atg agg gag acc cga aga act aga tcc agg ata aat gcc ttg gtg tca      48
  Met Arg Glu Thr Arg Arg Thr Arg Ser Arg Ile Asn Ala Leu Val Ser
    1               5                  10                  15

 cct ttg att ctt gtg ctt tta ttt ctc cat ctc tgg tgg gag agt cct       96
 Pro Leu Ile Leu Val Leu Leu Phe Leu His Leu Trp Trp Glu Ser Pro
              20                  25                  30

 gaa gat tct gta cct gaa gat aca gaa gat ctc cag cct ttt acc agg      144
 Glu Asp Ser Val Pro Glu Asp Thr Glu Asp Leu Gln Pro Phe Thr Arg
          35                  40                  45

 gta act gtt cac tgg gga aag gga aat gat cag aca ttt cgg gga cta      192
 Val Thr Val His Trp Gly Lys Gly Asn Asp Gln Thr Phe Arg Gly Leu
      50                  55                  60

 ctg gac act ggc ttt gag ctg aca tgg att cca ggg gac cca aaa tgt      240
 Leu Asp Thr Gly Phe Glu Leu Thr Trp Ile Pro Gly Asp Pro Lys Cys
  65                  70                  75                  80

 cat tgt ggt cct cta gtt aaa gta ggg ttt tat gaa ggt cag gta att      288
 His Cys Gly Pro Leu Val Lys Val Gly Phe Tyr Glu Gly Gln Val Ile
                  85                  90                  95

 agt aga gtt tta gct cag gta cga ctt aca gtg ggt cct cgc act cat      336
 Ser Arg Val Leu Ala Gln Val Arg Leu Thr Val Gly Pro Arg Thr His
             100                 105                 110

 cct gtg gtc att tcc cca gtg cca gaa tgc ata att ggc ata gac ata      384
 Pro Val Val Ile Ser Pro Val Pro Glu Cys Ile Ile Gly Ile Asp Ile
         115                 120                 125

 ctt agc agc tgg caa aac ccc cac att ggc tcc ctg act ggt agg cct      432
 Leu Ser Ser Trp Gln Asn Pro His Ile Gly Ser Leu Thr Gly Arg Pro
     130                 135                 140

 tca ctg atg gcc tca ggg gga att tcc tat gaa cag ctg aca gag gaa      480
 Ser Leu Met Ala Ser Gly Gly Ile Ser Tyr Glu Gln Leu Thr Glu Glu
 145                 150                 155                 160

 gag aag act agg gcc tgg ttt aca gat tgt tct gca caa tat gca ggc      528
 Glu Lys Thr Arg Ala Trp Phe Thr Asp Cys Ser Ala Gln Tyr Ala Gly
                 165                 170                 175

 acc acc cga aag tgg acg gct gca gca cta cag ccc ctt tct agg aca      576
 Thr Thr Arg Lys Trp Thr Ala Ala Ala Leu Gln Pro Leu Ser Arg Thr
             180                 185                 190

 tcc ctg aag gac agc agt gtc agg aaa tct tcc cac tgg att ggt aga      624
 Ser Leu Lys Asp Ser Ser Val Arg Lys Ser Ser His Trp Ile Gly Arg
         195                 200                 205

 act gtg gaa tgg tca ttt gaa gtc aca att aca atg aca gta ctt tgc      672
 Thr Val Glu Trp Ser Phe Glu Val Thr Ile Thr Met Thr Val Leu Cys
     210                 215                 220

 agg gct ggc cag aag gcc gtg tat gct ctg aat cag cat cca ata tat      720
 Arg Ala Gly Gln Lys Ala Val Tyr Ala Leu Asn Gln His Pro Ile Tyr
 225                 230                 235                 240

 gat act gtt tct ccc ata gcc agg att cat ggt cca gga atc aag gtg      768
 Asp Thr Val Ser Pro Ile Ala Arg Ile His Gly Pro Gly Ile Lys Val
                 245                 250                 255

 ggg aaa gtg gaa gta gaa cta ctc acc atc acc cct agt gat cca cta      816
 Gly Lys Val Glu Val Glu Leu Leu Thr Ile Thr Pro Ser Asp Pro Leu
             260                 265                 270

 gca aag tgt ttg ctt ccg gtt ccc acg aca tta tgt tct gct ggc cta      864
 Ala Lys Cys Leu Leu Pro Val Pro Thr Thr Leu Cys Ser Ala Gly Leu
         275                 280                 285

 gag gtc tta gat cca gag gga gaa att ctg cca cca gga gac aac aat      912
 Glu Val Leu Asp Pro Glu Gly Glu Ile Leu Pro Pro Gly Asp Asn Asn
     290                 295                 300

 gat tcc att aaa cta aaa gtt aag att gcc acc tgg aca ctt tgg att      960
 Asp Ser Ile Lys Leu Lys Val Lys Ile Ala Thr Trp Thr Leu Trp Ile
 305                 310                 315                 320

 cct cct act ttt aag tca aca ggc taa                                  987
 Pro Pro Thr Phe Lys Ser Thr Gly 
                 325





      <210> 872
      <211> 1422
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1422)

      <400> 872
  atg atg atg acc gtg atg atg aca atg gca atg gtg atc tca ttt cag      48
  Met Met Met Thr Val Met Met Thr Met Ala Met Val Ile Ser Phe Gln
    1               5                  10                  15

 cct ctc gcc ggc cct gtg aga atg aat atg cag gca ctg tac ggt ttg       96
 Pro Leu Ala Gly Pro Val Arg Met Asn Met Gln Ala Leu Tyr Gly Leu
              20                  25                  30

 gta gag cag tcc aaa gga tgg aca gac acg cag agc ccc aag ttc agt      144
 Val Glu Gln Ser Lys Gly Trp Thr Asp Thr Gln Ser Pro Lys Phe Ser
          35                  40                  45

 ggc aac acc cat gtg aac atc ggc ctg tct ttc ccg atc aca ggc ctt      192
 Gly Asn Thr His Val Asn Ile Gly Leu Ser Phe Pro Ile Thr Gly Leu
      50                  55                  60

 tgg atc cca tca aac tcg gac agc cag tgc agc ccc acg cgg cag agc      240
 Trp Ile Pro Ser Asn Ser Asp Ser Gln Cys Ser Pro Thr Arg Gln Ser
  65                  70                  75                  80

 ctc agc ctg tcg gaa ggc gag gag cag atg gac cgg ctg cag cag gtg      288
 Leu Ser Leu Ser Glu Gly Glu Glu Gln Met Asp Arg Leu Gln Gln Val
                  85                  90                  95

 gag ctg gtg agg acc acc cct atg tcc cac tgg aag gcg ggc acc gtc      336
 Glu Leu Val Arg Thr Thr Pro Met Ser His Trp Lys Ala Gly Thr Val
             100                 105                 110

 cag gcc tgg ctg gag gtg gtg atg gcc atg cct atg tac gtc aag gcc      384
 Gln Ala Trp Leu Glu Val Val Met Ala Met Pro Met Tyr Val Lys Ala
         115                 120                 125

 tgc acg gag aac gtg aag agc ggg aag gtg ctg ctg agc ctg agt gac      432
 Cys Thr Glu Asn Val Lys Ser Gly Lys Val Leu Leu Ser Leu Ser Asp
     130                 135                 140

 gag gac ctg cag ctg ggc ctt ggg gtg tgc agc tcc ctg cac cgg cgc      480
 Glu Asp Leu Gln Leu Gly Leu Gly Val Cys Ser Ser Leu His Arg Arg
 145                 150                 155                 160

 aag ctg cgc ctg gcc atc gag gac tac cgt gat gcc gag gca ggc cgc      528
 Lys Leu Arg Leu Ala Ile Glu Asp Tyr Arg Asp Ala Glu Ala Gly Arg
                 165                 170                 175

 agc ctg tcc aaa gct gcc gag ctg gac cat cac tgg gtg gcc aag gcc      576
 Ser Leu Ser Lys Ala Ala Glu Leu Asp His His Trp Val Ala Lys Ala
             180                 185                 190

 tgg ctg aat gac att ggc ctg tcc cag tac tcc cag gcc ttt cag aac      624
 Trp Leu Asn Asp Ile Gly Leu Ser Gln Tyr Ser Gln Ala Phe Gln Asn
         195                 200                 205

 cac ctg gtt gat ggg cgg atg ctg aat tcc ctg atg aag cga gac ctg      672
 His Leu Val Asp Gly Arg Met Leu Asn Ser Leu Met Lys Arg Asp Leu
     210                 215                 220

 gag aag cac ctg aac gtg tcc aag aag ttc cac cag gtc agc atc ctg      720
 Glu Lys His Leu Asn Val Ser Lys Lys Phe His Gln Val Ser Ile Leu
 225                 230                 235                 240

 ctg ggg atc gag ctg ctg tac caa gtg aac ttc agc agg gag gcc ctc      768
 Leu Gly Ile Glu Leu Leu Tyr Gln Val Asn Phe Ser Arg Glu Ala Leu
                 245                 250                 255

 cag gag cgc cgg gcc cgc tgc gag acg cag aac att gac ccc gtg gtg      816
 Gln Glu Arg Arg Ala Arg Cys Glu Thr Gln Asn Ile Asp Pro Val Val
             260                 265                 270

 tgg acc aac cag cgg gtg ctc aag tgg gtt cga gac atc gac ctg aag      864
 Trp Thr Asn Gln Arg Val Leu Lys Trp Val Arg Asp Ile Asp Leu Lys
         275                 280                 285

 gag tac gca gac aac ctg acc aac agc ggc gtc cat ggt gct gtg ctg      912
 Glu Tyr Ala Asp Asn Leu Thr Asn Ser Gly Val His Gly Ala Val Leu
     290                 295                 300

 gtg ctg gag ccc aca ttc aat gcc gag gcc atg gcc act gcc ctg ggc      960
 Val Leu Glu Pro Thr Phe Asn Ala Glu Ala Met Ala Thr Ala Leu Gly
 305                 310                 315                 320

 atc ccc agt ggg aag cac atc ctc cgg aga cac ctg gca gag gag atg     1008
 Ile Pro Ser Gly Lys His Ile Leu Arg Arg His Leu Ala Glu Glu Met
                 325                 330                 335

 agc gcc gtc ttc cac cca gcc aac tcc aca ggc atc cgg gag gct gag     1056
 Ser Ala Val Phe His Pro Ala Asn Ser Thr Gly Ile Arg Glu Ala Glu
             340                 345                 350

 cgt ttt gga acg ccc cct ggc agg gcc tcc agc gtc acg cgg gca gga     1104
 Arg Phe Gly Thr Pro Pro Gly Arg Ala Ser Ser Val Thr Arg Ala Gly
         355                 360                 365

 aag gag gag aac agc agc ggt ctc aag tac aag gct ggc cgg ctg ccc     1152
 Lys Glu Glu Asn Ser Ser Gly Leu Lys Tyr Lys Ala Gly Arg Leu Pro
     370                 375                 380

 ctg ggg aag ata gga agg ggc ttc agc agc aaa gat ccc gat ttc cat     1200
 Leu Gly Lys Ile Gly Arg Gly Phe Ser Ser Lys Asp Pro Asp Phe His
 385                 390                 395                 400

 gat gac tat ggc tct ctt caa aac gaa gat tgc gga gac gat gac ccc     1248
 Asp Asp Tyr Gly Ser Leu Gln Asn Glu Asp Cys Gly Asp Asp Asp Pro
                 405                 410                 415

 cag agc agg ctg gaa cag tgc cgt ctg gaa ggc tac aac agc ctg gag     1296
 Gln Ser Arg Leu Glu Gln Cys Arg Leu Glu Gly Tyr Asn Ser Leu Glu
             420                 425                 430

 gtc acc aac gtg gtc ctg aag ctg cag tcc aca gct cag aaa gga gag     1344
 Val Thr Asn Val Val Leu Lys Leu Gln Ser Thr Ala Gln Lys Gly Glu
         435                 440                 445

 gac cct cga cct ggc tcc cgt aca tct gtg tca tcc cag atg caa tta     1392
 Asp Pro Arg Pro Gly Ser Arg Thr Ser Val Ser Ser Gln Met Gln Leu
     450                 455                 460

 gtg ctt cct aag tgc tac acc tgg aca tga                             1422
 Val Leu Pro Lys Cys Tyr Thr Trp Thr 
 465                 470





      <210> 873
      <211> 480
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(480)

      <400> 873
  atg cat gtg gta atg att ttg att atg aaa tgc tta tct ttg gat ttt      48
  Met His Val Val Met Ile Leu Ile Met Lys Cys Leu Ser Leu Asp Phe
    1               5                  10                  15

 tct tgc att ttt cag gtc aat ggg aag gat ctt tca aag gcc act cat       96
 Ser Cys Ile Phe Gln Val Asn Gly Lys Asp Leu Ser Lys Ala Thr His
              20                  25                  30

 gaa gag gca gtg gaa gct ttt cgc aat gcc aag gag ccc att gtg gtg      144
 Glu Glu Ala Val Glu Ala Phe Arg Asn Ala Lys Glu Pro Ile Val Val
          35                  40                  45

 cag gtg tta agg cga aca cct ctt agt aga cca gcc tat ggg atg gct      192
 Gln Val Leu Arg Arg Thr Pro Leu Ser Arg Pro Ala Tyr Gly Met Ala
      50                  55                  60

 tca gaa gtg cag ctt atg aat gcc agc act cag acg gac atc acc ttc      240
 Ser Glu Val Gln Leu Met Asn Ala Ser Thr Gln Thr Asp Ile Thr Phe
  65                  70                  75                  80

 gaa cac atc atg gct ctg gcc aag ctt cgt cca cct acc cct cca gtg      288
 Glu His Ile Met Ala Leu Ala Lys Leu Arg Pro Pro Thr Pro Pro Val
                  85                  90                  95

 cca gac atc tgt cca ttc ctg ctc tca gac agg tat ttt tct atc att      336
 Pro Asp Ile Cys Pro Phe Leu Leu Ser Asp Arg Tyr Phe Ser Ile Ile
             100                 105                 110

 tct tcc aaa gcc ctg ttt gtt tcc att tgt cac gta aag cag atg ttg      384
 Ser Ser Lys Ala Leu Phe Val Ser Ile Cys His Val Lys Gln Met Leu
         115                 120                 125

 aaa aga agc agt tcc act agc agg ttg aca gtt atg gag aca ggc ttc      432
 Lys Arg Ser Ser Ser Thr Ser Arg Leu Thr Val Met Glu Thr Gly Phe
     130                 135                 140

 cca gct ccg ttt gga aaa tgt ctc ccc tgt ttt gat atg tgc aat tag      480
 Pro Ala Pro Phe Gly Lys Cys Leu Pro Cys Phe Asp Met Cys Asn 
 145                 150                 155





      <210> 874
      <211> 294
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(294)

      <400> 874
  atg ggg cag ttt ctc act cat tgg tct gct gtc acg att tta atg agc      48
  Met Gly Gln Phe Leu Thr His Trp Ser Ala Val Thr Ile Leu Met Ser
    1               5                  10                  15

 tca tgc aca aac agc cct tta tat aag gga gca gaa cac acc tct tat       96
 Ser Cys Thr Asn Ser Pro Leu Tyr Lys Gly Ala Glu His Thr Ser Tyr
              20                  25                  30

 gtg tca gaa aac aaa gtc cag gaa gta tat ttt tac ctg agg caa tat      144
 Val Ser Glu Asn Lys Val Gln Glu Val Tyr Phe Tyr Leu Arg Gln Tyr
          35                  40                  45

 ctg aaa att gta tgc tac agc ctc caa agt gag tct tcc tct cag tac      192
 Leu Lys Ile Val Cys Tyr Ser Leu Gln Ser Glu Ser Ser Ser Gln Tyr
      50                  55                  60

 ctc tct tct agg cac atg gag ccc ttt ctt cca agt att atg ttt aac      240
 Leu Ser Ser Arg His Met Glu Pro Phe Leu Pro Ser Ile Met Phe Asn
  65                  70                  75                  80

 cac tta atg aat gaa gtc ctg aaa ctg ctt acc cat gct ccc tat aat      288
 His Leu Met Asn Glu Val Leu Lys Leu Leu Thr His Ala Pro Tyr Asn
                  85                  90                  95

 ctc tga                                                              294
 Leu 






      <210> 875
      <211> 1332
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1332)

      <400> 875
  atg aaa gcc atg ccc tgg aac tgg acc tgc ctt ctc tcc cac ctc ctc      48
  Met Lys Ala Met Pro Trp Asn Trp Thr Cys Leu Leu Ser His Leu Leu
    1               5                  10                  15

 atg gtg ggc atg ggc tcc tcc act ttg ctc acc cgg cag cca gcc ccg       96
 Met Val Gly Met Gly Ser Ser Thr Leu Leu Thr Arg Gln Pro Ala Pro
              20                  25                  30

 ctg tcc cag aag cag cgg tca ttt gtc aca ttc cga gga gag ccc gcc      144
 Leu Ser Gln Lys Gln Arg Ser Phe Val Thr Phe Arg Gly Glu Pro Ala
          35                  40                  45

 gag ggt ttc aat cac ctg gtg gtg gat gag agg aca gga cac att tac      192
 Glu Gly Phe Asn His Leu Val Val Asp Glu Arg Thr Gly His Ile Tyr
      50                  55                  60

 ttg ggg gcc gtc aat cgg att tac aag ctc tcc agc gac ctg aag gtc      240
 Leu Gly Ala Val Asn Arg Ile Tyr Lys Leu Ser Ser Asp Leu Lys Val
  65                  70                  75                  80

 ttg gtg acg cat gag aca ggg ccg gac gag gac aac ccc aag tgt tac      288
 Leu Val Thr His Glu Thr Gly Pro Asp Glu Asp Asn Pro Lys Cys Tyr
                  85                  90                  95

 cca ccc cgc atc gtc cag acc tgc aat gag ccc ctg acc acc acc aac      336
 Pro Pro Arg Ile Val Gln Thr Cys Asn Glu Pro Leu Thr Thr Thr Asn
             100                 105                 110

 aat gtc aac aag atg ctc ctc ata gac tac aag gag aac agg ctg att      384
 Asn Val Asn Lys Met Leu Leu Ile Asp Tyr Lys Glu Asn Arg Leu Ile
         115                 120                 125

 gcc tgt ggg agc ctg tac caa ggc atc tgc aag ctg ctg agg ctg gag      432
 Ala Cys Gly Ser Leu Tyr Gln Gly Ile Cys Lys Leu Leu Arg Leu Glu
     130                 135                 140

 gac ctc ttc aag ctg ggg gag cct tat cat aag aag gag cac tat ctg      480
 Asp Leu Phe Lys Leu Gly Glu Pro Tyr His Lys Lys Glu His Tyr Leu
 145                 150                 155                 160

 tca ggt gtc aac gag agc ggc tcg gtc ttt gga gtg atc gtc tcc tac      528
 Ser Gly Val Asn Glu Ser Gly Ser Val Phe Gly Val Ile Val Ser Tyr
                 165                 170                 175

 agc aac ctg gat gac aag ctg ttc att gcc acg gca gtg gat ggg aag      576
 Ser Asn Leu Asp Asp Lys Leu Phe Ile Ala Thr Ala Val Asp Gly Lys
             180                 185                 190

 ccc gag tat ttt ccc acc atc tcc agc cgg aaa ctg acc aag aac tct      624
 Pro Glu Tyr Phe Pro Thr Ile Ser Ser Arg Lys Leu Thr Lys Asn Ser
         195                 200                 205

 gag gcg gat ggc atg ttc gcg tac gtc ttc cat gat gag ttc gtg gcc      672
 Glu Ala Asp Gly Met Phe Ala Tyr Val Phe His Asp Glu Phe Val Ala
     210                 215                 220

 tcg atg att aag atc cct tcg gac acc ttc acc atc atc cct gac ttt      720
 Ser Met Ile Lys Ile Pro Ser Asp Thr Phe Thr Ile Ile Pro Asp Phe
 225                 230                 235                 240

 gat atc tac tat gtc tat ggt ttt agc agt ggc aac ttt gtc tac ttt      768
 Asp Ile Tyr Tyr Val Tyr Gly Phe Ser Ser Gly Asn Phe Val Tyr Phe
                 245                 250                 255

 ttg acc ctc caa cct gag atg gtg tct cca cca ggc tcc acc acc aag      816
 Leu Thr Leu Gln Pro Glu Met Val Ser Pro Pro Gly Ser Thr Thr Lys
             260                 265                 270

 gag cag gtg tat aca tcc aag ctc gtg agg ctt tgc aag gag gac aca      864
 Glu Gln Val Tyr Thr Ser Lys Leu Val Arg Leu Cys Lys Glu Asp Thr
         275                 280                 285

 gcc ttc aac tcc tat gta gag gtg ccc att ggc tgt gag cgc agt ggg      912
 Ala Phe Asn Ser Tyr Val Glu Val Pro Ile Gly Cys Glu Arg Ser Gly
     290                 295                 300

 gtg gag tac cgc ctg ctg cag gct gcc tac ctg tcc aaa gcg ggg gcc      960
 Val Glu Tyr Arg Leu Leu Gln Ala Ala Tyr Leu Ser Lys Ala Gly Ala
 305                 310                 315                 320

 gtg ctt ggc agg acc ctt gga gtc cat cca gat gat gac ctg ctc ttc     1008
 Val Leu Gly Arg Thr Leu Gly Val His Pro Asp Asp Asp Leu Leu Phe
                 325                 330                 335

 acc gtc ttc tcc aag ggc cag aag cgg aaa atg aaa tcc ctg gat gag     1056
 Thr Val Phe Ser Lys Gly Gln Lys Arg Lys Met Lys Ser Leu Asp Glu
             340                 345                 350

 tcg gcc ctg tgc atc ttc atc ttg aag cag ata aat gac cgc att aag     1104
 Ser Ala Leu Cys Ile Phe Ile Leu Lys Gln Ile Asn Asp Arg Ile Lys
         355                 360                 365

 gag cgg ctg cag tct tgt tac cgg ggc gag ggc acg ctg gac ctg gcc     1152
 Glu Arg Leu Gln Ser Cys Tyr Arg Gly Glu Gly Thr Leu Asp Leu Ala
     370                 375                 380

 tgg ctt aag gtg aag gac atc ccc tgc agc agt gcg gtc tac ctc ctc     1200
 Trp Leu Lys Val Lys Asp Ile Pro Cys Ser Ser Ala Val Tyr Leu Leu
 385                 390                 395                 400

 ctc cag ccc ttc cca ggg agt ctc cac aga gac tac cag gca ctt ctg     1248
 Leu Gln Pro Phe Pro Gly Ser Leu His Arg Asp Tyr Gln Ala Leu Leu
                 405                 410                 415

 ggg tcc ttg ggc agt ggc agt ggc ttt gca gct ctg ccc ctg agc ctg     1296
 Gly Ser Leu Gly Ser Gly Ser Gly Phe Ala Ala Leu Pro Leu Ser Leu
             420                 425                 430

 ggg aac tgc tgg agg aag gaa acc gtc tgc att taa                     1332
 Gly Asn Cys Trp Arg Lys Glu Thr Val Cys Ile 
         435                 440





      <210> 876
      <211> 543
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(543)

      <400> 876
  atg ctg ctc tac ctc cca ccc gcc ctg agc act cgg tgg atg ctg gga      48
  Met Leu Leu Tyr Leu Pro Pro Ala Leu Ser Thr Arg Trp Met Leu Gly
    1               5                  10                  15

 ctc tgc cgg cca gcc aac cag aaa agg gcg cat gag gct cac gcc aag       96
 Leu Cys Arg Pro Ala Asn Gln Lys Arg Ala His Glu Ala His Ala Lys
              20                  25                  30

 ccg gct tcc gct ctg tcc atc aat tca ggc cca ctg agc aca ggt tct      144
 Pro Ala Ser Ala Leu Ser Ile Asn Ser Gly Pro Leu Ser Thr Gly Ser
          35                  40                  45

 cgg gga atg ctc aag agc ccc atg cca gtg gtg gag ttc tac gtg gct      192
 Arg Gly Met Leu Lys Ser Pro Met Pro Val Val Glu Phe Tyr Val Ala
      50                  55                  60

 ggg att ggg aca tca gtg gac cca ggg acg gcc cca agg aag ggg cta      240
 Gly Ile Gly Thr Ser Val Asp Pro Gly Thr Ala Pro Arg Lys Gly Leu
  65                  70                  75                  80

 ggt ctc aga cat aag gag gag ggg gca ggt ctt cag gcc cac agg ccc      288
 Gly Leu Arg His Lys Glu Glu Gly Ala Gly Leu Gln Ala His Arg Pro
                  85                  90                  95

 gtc tgg ggc tca gag ggc ttt gcc cag gcc gtc cag ggg cct gga ggc      336
 Val Trp Gly Ser Glu Gly Phe Ala Gln Ala Val Gln Gly Pro Gly Gly
             100                 105                 110

 tgc aga acg tgc agc aaa caa cag ccc atg cct ttt gcc aag acc gac      384
 Cys Arg Thr Cys Ser Lys Gln Gln Pro Met Pro Phe Ala Lys Thr Asp
         115                 120                 125

 acc tgt gcc tca gac aaa cac gtg gag aag aag ctg ttc cat gtg caa      432
 Thr Cys Ala Ser Asp Lys His Val Glu Lys Lys Leu Phe His Val Gln
     130                 135                 140

 act gac act aat gcc atc tcc ttc ctc aca ctg ctg agc gtg gaa ggg      480
 Thr Asp Thr Asn Ala Ile Ser Phe Leu Thr Leu Leu Ser Val Glu Gly
 145                 150                 155                 160

 gac cct ggc ata caa atc tgc atc aca gaa gat atc cag ttg ggc aag      528
 Asp Pro Gly Ile Gln Ile Cys Ile Thr Glu Asp Ile Gln Leu Gly Lys
                 165                 170                 175

 acc ccg cct ccc tga                                                  543
 Thr Pro Pro Pro 
             180





      <210> 877
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 877
  atg ggg tgg gct ctg cct ggc gcc ctg ggc gga gtg ctt ggg ctg gaa      48
  Met Gly Trp Ala Leu Pro Gly Ala Leu Gly Gly Val Leu Gly Leu Glu
    1               5                  10                  15

 ggg atc ctg cct gcg atc ccg aag tcc agg cgt ggg agc cag cga tct       96
 Gly Ile Leu Pro Ala Ile Pro Lys Ser Arg Arg Gly Ser Gln Arg Ser
              20                  25                  30

 gcc cac gac ccc aaa gtg agc cac tcc acg gcc tct ggg gca aat gcc      144
 Ala His Asp Pro Lys Val Ser His Ser Thr Ala Ser Gly Ala Asn Ala
          35                  40                  45

 tgt tat tct agg cag ccg gtc ccc aga agc tgg aaa gta cgt aaa agt      192
 Cys Tyr Ser Arg Gln Pro Val Pro Arg Ser Trp Lys Val Arg Lys Ser
      50                  55                  60

 gcc aga agc tcc cat gct gaa aac taa                                  219
 Ala Arg Ser Ser His Ala Glu Asn 
  65                  70





      <210> 878
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 878
  atg gca ctg ttc cag gca ggc ctg gtt atc ctg ctt gag gca gca atc      48
  Met Ala Leu Phe Gln Ala Gly Leu Val Ile Leu Leu Glu Ala Ala Ile
    1               5                  10                  15

 ctc ttg agc cta gtg aaa tgc aac tgg ctg tac ctc agt gat gtc gcg       96
 Leu Leu Ser Leu Val Lys Cys Asn Trp Leu Tyr Leu Ser Asp Val Ala
              20                  25                  30

 ctg aga ttc tgc cag tca aga tat tac ttc aat ctc ctg aga caa gcc      144
 Leu Arg Phe Cys Gln Ser Arg Tyr Tyr Phe Asn Leu Leu Arg Gln Ala
          35                  40                  45

 tct acc tcc aga tcc agg aag gtg agc aag gtc atg ctc gtg ctg aag      192
 Ser Thr Ser Arg Ser Arg Lys Val Ser Lys Val Met Leu Val Leu Lys
      50                  55                  60

 gct ctg gag tct tca gac ctc acc gag gtt gtc ggt tac ggc ttc tat      240
 Ala Leu Glu Ser Ser Asp Leu Thr Glu Val Val Gly Tyr Gly Phe Tyr
  65                  70                  75                  80

 tta tac aag tgc cag acc aag tgg atg ccc cag tcc atg gct gag tgg      288
 Leu Tyr Lys Cys Gln Thr Lys Trp Met Pro Gln Ser Met Ala Glu Trp
                  85                  90                  95

 cac tgc cag tgc cag gag cga ggg atg ctc aaa ctt gtg gaa agc atg      336
 His Cys Gln Cys Gln Glu Arg Gly Met Leu Lys Leu Val Glu Ser Met
             100                 105                 110

 aat gcc gtc aaa cta cgc cct tgg gtg aag tga                          369
 Asn Ala Val Lys Leu Arg Pro Trp Val Lys 
         115                 120





      <210> 879
      <211> 582
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(582)

      <400> 879
  atg tct ctg cag gtt tct gaa gct ctc agc aga gaa gag gcc cta gaa      48
  Met Ser Leu Gln Val Ser Glu Ala Leu Ser Arg Glu Glu Ala Leu Glu
    1               5                  10                  15

 tgg ata gct tct ctc ttc tgc tgg ttg ttg gga cat ctt ctg ctg tca       96
 Trp Ile Ala Ser Leu Phe Cys Trp Leu Leu Gly His Leu Leu Leu Ser
              20                  25                  30

 gca gaa agg gta gct ctt ctc tgc agc tgg tca tcc atc atc tgc tct      144
 Ala Glu Arg Val Ala Leu Leu Cys Ser Trp Ser Ser Ile Ile Cys Ser
          35                  40                  45

 gct ctg gct gag cct ggg gct ttt ata ggc cta tta gag ggg aag tgc      192
 Ala Leu Ala Glu Pro Gly Ala Phe Ile Gly Leu Leu Glu Gly Lys Cys
      50                  55                  60

 atg ctg atc agt cca tgg gca gcc atg ggc aga tcc agg aaa aac cac      240
 Met Leu Ile Ser Pro Trp Ala Ala Met Gly Arg Ser Arg Lys Asn His
  65                  70                  75                  80

 cac gag ttt gcc ctc caa atc agc act gcc agt cct gtc ccc agg ctt      288
 His Glu Phe Ala Leu Gln Ile Ser Thr Ala Ser Pro Val Pro Arg Leu
                  85                  90                  95

 cag gcc ttc tct cag gga tct gcc ctc ttc tgc cca aag tgc agg gat      336
 Gln Ala Phe Ser Gln Gly Ser Ala Leu Phe Cys Pro Lys Cys Arg Asp
             100                 105                 110

 acc tgg gtc tgc agc cgc aat atg ggc tgc tcc ctt gac cct agg gaa      384
 Thr Trp Val Cys Ser Arg Asn Met Gly Cys Ser Leu Asp Pro Arg Glu
         115                 120                 125

 gtg gag ctc ctg gtc ccc caa aaa ata caa gtc aat gac cag att gtg      432
 Val Glu Leu Leu Val Pro Gln Lys Ile Gln Val Asn Asp Gln Ile Val
     130                 135                 140

 gaa gtg gat gga atc agc ttg gtg ggt gtg aca cag aat ttt gca gca      480
 Glu Val Asp Gly Ile Ser Leu Val Gly Val Thr Gln Asn Phe Ala Ala
 145                 150                 155                 160

 aca gtt ctc aga aac acc aag ggc aac gtc agg caa tat ggt cat tta      528
 Thr Val Leu Arg Asn Thr Lys Gly Asn Val Arg Gln Tyr Gly His Leu
                 165                 170                 175

 tac aca gat gac cat gaa gaa aat cct aaa gta tct aca aaa gat gct      576
 Tyr Thr Asp Asp His Glu Glu Asn Pro Lys Val Ser Thr Lys Asp Ala
             180                 185                 190

 act tga                                                              582
 Thr 






      <210> 880
      <211> 447
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(447)

      <400> 880
  atg ggg tcc tgc cac tcg agc cag acc ctc ctt ccc ttc ccg ttt tgg      48
  Met Gly Ser Cys His Ser Ser Gln Thr Leu Leu Pro Phe Pro Phe Trp
    1               5                  10                  15

 gct cta agt gct gcc ccc tgt gag aga atg tgc tgg agg agc ccc cag       96
 Ala Leu Ser Ala Ala Pro Cys Glu Arg Met Cys Trp Arg Ser Pro Gln
              20                  25                  30

 tat cct tcc agc ggg aag tcg gct ctg tca agg cca ttc ctg aga gca      144
 Tyr Pro Ser Ser Gly Lys Ser Ala Leu Ser Arg Pro Phe Leu Arg Ala
          35                  40                  45

 ggc tct agg aat tca aag acc aag cag gca gag ctg gat tct gga gct      192
 Gly Ser Arg Asn Ser Lys Thr Lys Gln Ala Glu Leu Asp Ser Gly Ala
      50                  55                  60

 gcc ctc aaa ggg ctt gag ggt tat atg agc gcc gtg ctt gag aaa aat      240
 Ala Leu Lys Gly Leu Glu Gly Tyr Met Ser Ala Val Leu Glu Lys Asn
  65                  70                  75                  80

 agc agc agg ctg gtt gct ctt ctc agc ttc agc tgt agc cac ccc agt      288
 Ser Ser Arg Leu Val Ala Leu Leu Ser Phe Ser Cys Ser His Pro Ser
                  85                  90                  95

 ttc agg agg aag tgc ccg tgg ttc ctg ggg cct gga agt gcc gct caa      336
 Phe Arg Arg Lys Cys Pro Trp Phe Leu Gly Pro Gly Ser Ala Ala Gln
             100                 105                 110

 ctc tgc tgc cag aca agt gcg ggc gtg gtg gac tgc act ggg tac act      384
 Leu Cys Cys Gln Thr Ser Ala Gly Val Val Asp Cys Thr Gly Tyr Thr
         115                 120                 125

 gct gta ccg gcc acc acc ctc cgg cca ctc tca gcc ggg ata gat cca      432
 Ala Val Pro Ala Thr Thr Leu Arg Pro Leu Ser Ala Gly Ile Asp Pro
     130                 135                 140

 cca atg ttc agc tga                                                  447
 Pro Met Phe Ser 
 145





      <210> 881
      <211> 123
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(123)

      <400> 881
  atg tgg gat tct ctc aaa ctg cta gta gca ctt gtc tta gac att ctt      48
  Met Trp Asp Ser Leu Lys Leu Leu Val Ala Leu Val Leu Asp Ile Leu
    1               5                  10                  15

 agt tca gaa aaa ggt agt gct gat gag tcc tta gag tca ttt agt ggc       96
 Ser Ser Glu Lys Gly Ser Ala Asp Glu Ser Leu Glu Ser Phe Ser Gly
              20                  25                  30

 cag tct cat ttt cga aat gga aac taa                                  123
 Gln Ser His Phe Arg Asn Gly Asn 
          35                  40





      <210> 882
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 882
  atg ctc caa gta ctg gac ctt ctg ttt ttt gtt acc atg acc gag aat      48
  Met Leu Gln Val Leu Asp Leu Leu Phe Phe Val Thr Met Thr Glu Asn
    1               5                  10                  15

 tca tac att gtg ttt gaa gca tca aat gag tta aac aca ttt aat att       96
 Ser Tyr Ile Val Phe Glu Ala Ser Asn Glu Leu Asn Thr Phe Asn Ile
              20                  25                  30

 atc atg atg att cca aat gaa tta atc att aat tat ggc cag acc cca      144
 Ile Met Met Ile Pro Asn Glu Leu Ile Ile Asn Tyr Gly Gln Thr Pro
          35                  40                  45

 ttg tgc agg aat aca ctt agt gac aat cat gac atg tca gga ata gaa      192
 Leu Cys Arg Asn Thr Leu Ser Asp Asn His Asp Met Ser Gly Ile Glu
      50                  55                  60

 ggt ctg agt ttt cct ctg agc cat tat gca gag cag cct ttg gtc acc      240
 Gly Leu Ser Phe Pro Leu Ser His Tyr Ala Glu Gln Pro Leu Val Thr
  65                  70                  75                  80

 aat tac agc aaa ata aac att cct tac ctg ctc cag ttg gta agc cgt      288
 Asn Tyr Ser Lys Ile Asn Ile Pro Tyr Leu Leu Gln Leu Val Ser Arg
                  85                  90                  95

 gct ttg gca gag agc cct cag agt cag aga aat gac tga                  327
 Ala Leu Ala Glu Ser Pro Gln Ser Gln Arg Asn Asp 
             100                 105





      <210> 883
      <211> 315
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(315)

      <400> 883
  atg aac tac ctt ctg tgg ccc atg gtt tta act cgc ata act tgt act      48
  Met Asn Tyr Leu Leu Trp Pro Met Val Leu Thr Arg Ile Thr Cys Thr
    1               5                  10                  15

 aac act atg agt ttt cct ctt aac ccc tgt cta acc aga aga agt gca       96
 Asn Thr Met Ser Phe Pro Leu Asn Pro Cys Leu Thr Arg Arg Ser Ala
              20                  25                  30

 aga ttt aac agt cca tgc tct gca gcc cct gga aac agc agt agc agc      144
 Arg Phe Asn Ser Pro Cys Ser Ala Ala Pro Gly Asn Ser Ser Ser Ser
          35                  40                  45

 agc agc aag gtc cag cat cca cca gat tct cac aag cct ttg act gtg      192
 Ser Ser Lys Val Gln His Pro Pro Asp Ser His Lys Pro Leu Thr Val
      50                  55                  60

 tgg act cag cca cag act ctg cct cta gct gac gtc aaa gtc cct gtc      240
 Trp Thr Gln Pro Gln Thr Leu Pro Leu Ala Asp Val Lys Val Pro Val
  65                  70                  75                  80

 aca tgg cca gat gaa agc caa gag atc att ggt tgt cgt agc aac cac      288
 Thr Trp Pro Asp Glu Ser Gln Glu Ile Ile Gly Cys Arg Ser Asn His
                  85                  90                  95

 aga ccg gct ctg aaa tta ttt caa tag                                  315
 Arg Pro Ala Leu Lys Leu Phe Gln 
             100





      <210> 884
      <211> 555
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(555)

      <400> 884
  atg aag act agc cgc cgc ggc cga gcg ctc ctg gcc gtg gcc ctg aac      48
  Met Lys Thr Ser Arg Arg Gly Arg Ala Leu Leu Ala Val Ala Leu Asn
    1               5                  10                  15

 ctg ctg gcg ctg ctg ttc gcc acc acc gct ttc ctc acc acg cac tgg       96
 Leu Leu Ala Leu Leu Phe Ala Thr Thr Ala Phe Leu Thr Thr His Trp
              20                  25                  30

 tgc cag ggc acg cag cgg gtc ccc aag ccg ggc tgc ggc cag ggc ggg      144
 Cys Gln Gly Thr Gln Arg Val Pro Lys Pro Gly Cys Gly Gln Gly Gly
          35                  40                  45

 cgc gcc aac tgc ccc aac tcg ggc gcc aac gcc acg gcc aac ggc acc      192
 Arg Ala Asn Cys Pro Asn Ser Gly Ala Asn Ala Thr Ala Asn Gly Thr
      50                  55                  60

 gcc gcc ccc gcc gcc gcc gcc gcc gcc gcc acc gcc tcg ggg aac ggc      240
 Ala Ala Pro Ala Ala Ala Ala Ala Ala Ala Thr Ala Ser Gly Asn Gly
  65                  70                  75                  80

 ccc cct ggc ggc gcg ctc tac agc tgg gag acc ggc gac gac cgc ttc      288
 Pro Pro Gly Gly Ala Leu Tyr Ser Trp Glu Thr Gly Asp Asp Arg Phe
                  85                  90                  95

 ctc ttc agg aat ttc cac acc ggc atc tgg tac tcg tgc gag gag gag      336
 Leu Phe Arg Asn Phe His Thr Gly Ile Trp Tyr Ser Cys Glu Glu Glu
             100                 105                 110

 ctc agc ggg ctt gat cca cag acc cgg gag cct tcc acc ccc atc gcc      384
 Leu Ser Gly Leu Asp Pro Gln Thr Arg Glu Pro Ser Thr Pro Ile Ala
         115                 120                 125

 aac cca cgc cga acc tcc cag acg gga gaa ctc ttc cat aag aca acc      432
 Asn Pro Arg Arg Thr Ser Gln Thr Gly Glu Leu Phe His Lys Thr Thr
     130                 135                 140

 ccg tac aag tct ctg ctc aaa tgt cct cca gtt tgt gag gcc ttc ctg      480
 Pro Tyr Lys Ser Leu Leu Lys Cys Pro Pro Val Cys Glu Ala Phe Leu
 145                 150                 155                 160

 gac cac ccc act gaa att agc cgc ctt gct gcc cgc cgg cac tcc cct      528
 Asp His Pro Thr Glu Ile Ser Arg Leu Ala Ala Arg Arg His Ser Pro
                 165                 170                 175

 gca ccc ctg atg tcc cca ctg ctc tga                                  555
 Ala Pro Leu Met Ser Pro Leu Leu 
             180





      <210> 885
      <211> 513
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(513)

      <400> 885
  atg ggg aag gcg gcg gcg gcg gtg gcc ttt ggg gcc gaa gtg ggc gtg      48
  Met Gly Lys Ala Ala Ala Ala Val Ala Phe Gly Ala Glu Val Gly Val
    1               5                  10                  15

 cgg ctc gcg ctg ttc gcg gcc ttc ctg gtg acg gag ctg ctc ccc ccg       96
 Arg Leu Ala Leu Phe Ala Ala Phe Leu Val Thr Glu Leu Leu Pro Pro
              20                  25                  30

 ttc cag aga ctc atc cag ccg gag gag atg tgg ctc tac cgg aac ccc      144
 Phe Gln Arg Leu Ile Gln Pro Glu Glu Met Trp Leu Tyr Arg Asn Pro
          35                  40                  45

 tac gtg gag gcg gag tat ttc ccc acc aag ccg atg cca cgc cca gat      192
 Tyr Val Glu Ala Glu Tyr Phe Pro Thr Lys Pro Met Pro Arg Pro Asp
      50                  55                  60

 ttc ttc tac cgc tgc ttc cct gat ggg cta gcc cat tct gac ttg atg      240
 Phe Phe Tyr Arg Cys Phe Pro Asp Gly Leu Ala His Ser Asp Leu Met
  65                  70                  75                  80

 tgt aca ggg gat aag gac gtg gtg aat gag ggc cga aag agc ttc ccc      288
 Cys Thr Gly Asp Lys Asp Val Val Asn Glu Gly Arg Lys Ser Phe Pro
                  85                  90                  95

 agt gga cat tct tcc tct gtg att gca ctg tcc cgc aca tgt gac tac      336
 Ser Gly His Ser Ser Ser Val Ile Ala Leu Ser Arg Thr Cys Asp Tyr
             100                 105                 110

 aag cat cac tgg caa gat gta cta gtt gga tcc atg att gga atg aca      384
 Lys His His Trp Gln Asp Val Leu Val Gly Ser Met Ile Gly Met Thr
         115                 120                 125

 ttt gcc tat gtc tgc tat cgg cag tat tat cct cct ctg act gat gca      432
 Phe Ala Tyr Val Cys Tyr Arg Gln Tyr Tyr Pro Pro Leu Thr Asp Ala
     130                 135                 140

 gaa tgc cat aaa cca ttt caa gac aaa ctt gta ctt tcc act gca cag      480
 Glu Cys His Lys Pro Phe Gln Asp Lys Leu Val Leu Ser Thr Ala Gln
 145                 150                 155                 160

 aag cct ggg gat tct tat tgt ttt gat att taa                          513
 Lys Pro Gly Asp Ser Tyr Cys Phe Asp Ile 
                 165                 170





      <210> 886
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 886
  atg tcc aaa cgg ggc ctg atg ccc atc tgg gcc ctg ggt gtc cac ctg      48
  Met Ser Lys Arg Gly Leu Met Pro Ile Trp Ala Leu Gly Val His Leu
    1               5                  10                  15

 cag cat gga tgt cca ctg gta ctt tat atc cac cag ggg cct aat gtc       96
 Gln His Gly Cys Pro Leu Val Leu Tyr Ile His Gln Gly Pro Asn Val
              20                  25                  30

 cac cta aga cct ggt gtt cac ctg ggg tct gat gtt cag ctg aag acc      144
 His Leu Arg Pro Gly Val His Leu Gly Ser Asp Val Gln Leu Lys Thr
          35                  40                  45

 gga tgt cca cct gga gcc gag gaa tcc act cag gga ctg gtg ttg aac      192
 Gly Cys Pro Pro Gly Ala Glu Glu Ser Thr Gln Gly Leu Val Leu Asn
      50                  55                  60

 tgg ggc ctg atg acc acc cgg gga caa ggt ctt gtg ttc atc ttt gac      240
 Trp Gly Leu Met Thr Thr Arg Gly Gln Gly Leu Val Phe Ile Phe Asp
  65                  70                  75                  80

 ctg gtg tac acc tgg gac acc tac gga ctt ggt gtc cag ttg agg tgt      288
 Leu Val Tyr Thr Trp Asp Thr Tyr Gly Leu Gly Val Gln Leu Arg Cys
                  85                  90                  95

 cat gac cac ctg ggg act gaa tgt caa tct ggg gtc tga                  327
 His Asp His Leu Gly Thr Glu Cys Gln Ser Gly Val 
             100                 105





      <210> 887
      <211> 393
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(393)

      <400> 887
  atg gct gtg tgt tgt ggt ttc ttc ctc cct cag tac atc cag cca ttg      48
  Met Ala Val Cys Cys Gly Phe Phe Leu Pro Gln Tyr Ile Gln Pro Leu
    1               5                  10                  15

 aca tta gta tcc tac aca cct gac ttg ctc ttg agt gtc aga ggt gaa       96
 Thr Leu Val Ser Tyr Thr Pro Asp Leu Leu Leu Ser Val Arg Gly Glu
              20                  25                  30

 agg aaa aat gaa aca gac agc agc ctc aac cag gag gct ccc acg gag      144
 Arg Lys Asn Glu Thr Asp Ser Ser Leu Asn Gln Glu Ala Pro Thr Glu
          35                  40                  45

 gag gcc agc tct gtt ttc ccc aag ctg acg tct gcg aag ccc ttc agt      192
 Glu Ala Ser Ser Val Phe Pro Lys Leu Thr Ser Ala Lys Pro Phe Ser
      50                  55                  60

 tct cta ccc gat ctg agg aat atc aat ctc agc agc tcg aag ttg gag      240
 Ser Leu Pro Asp Leu Arg Asn Ile Asn Leu Ser Ser Ser Lys Leu Glu
  65                  70                  75                  80

 ccc agt aaa ccc aac ttc agc atc aag gag gcc aag tct gcc tct gca      288
 Pro Ser Lys Pro Asn Phe Ser Ile Lys Glu Ala Lys Ser Ala Ser Ala
                  85                  90                  95

 gtg aac gta ttc act ggc act gtg att tgc tcg tcc act ccc ttg gtt      336
 Val Asn Val Phe Thr Gly Thr Val Ile Cys Ser Ser Thr Pro Leu Val
             100                 105                 110

 tca gct atg cca ctc atg tca gga ata acc tgc agc tcc aac cca gct      384
 Ser Ala Met Pro Leu Met Ser Gly Ile Thr Cys Ser Ser Asn Pro Ala
         115                 120                 125

 ctt tgc tga                                                          393
 Leu Cys 
     130





      <210> 888
      <211> 822
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(822)

      <400> 888
  atg aac ctc agt ttc ctt ctc tgc tgg ttg atg ggc ctg ggg gct ttc      48
  Met Asn Leu Ser Phe Leu Leu Cys Trp Leu Met Gly Leu Gly Ala Phe
    1               5                  10                  15

 caa gag ctt gtc att cca aga ggc cca aag gaa atc atc tta aac aaa       96
 Gln Glu Leu Val Ile Pro Arg Gly Pro Lys Glu Ile Ile Leu Asn Lys
              20                  25                  30

 gcc ttg tgt aag gat tgg gtc agc cca gac cag ggt tca aac tgg cta      144
 Ala Leu Cys Lys Asp Trp Val Ser Pro Asp Gln Gly Ser Asn Trp Leu
          35                  40                  45

 gca ttt tac ctc cag atc caa ccc cag atc tct ccc tcc aag ctt ctg      192
 Ala Phe Tyr Leu Gln Ile Gln Pro Gln Ile Ser Pro Ser Lys Leu Leu
      50                  55                  60

 aaa gcg act ttg act gca aat gga tct tct gag ttt aat ggc att gtc      240
 Lys Ala Thr Leu Thr Ala Asn Gly Ser Ser Glu Phe Asn Gly Ile Val
  65                  70                  75                  80

 atg tct cct ggt ggc agc att cct ccc tct aga act aag acc ttt agg      288
 Met Ser Pro Gly Gly Ser Ile Pro Pro Ser Arg Thr Lys Thr Phe Arg
                  85                  90                  95

 cca gca gaa cgt aat gta gag gga aca gga agc aaa aat ttt gct aac      336
 Pro Ala Glu Arg Asn Val Glu Gly Thr Gly Ser Lys Asn Phe Ala Asn
             100                 105                 110

 gaa tca cta ggg gtg ttg ttt cca cca aag ccc agt aac agg cca aga      384
 Glu Ser Leu Gly Val Leu Phe Pro Pro Lys Pro Ser Asn Arg Pro Arg
         115                 120                 125

 gct gtc tct gaa aag aag agt aat tat ctg ctg aag atg gca ggg cct      432
 Ala Val Ser Glu Lys Lys Ser Asn Tyr Leu Leu Lys Met Ala Gly Pro
     130                 135                 140

 tac tcc aaa atc cta gag gct tct gct gtt att cac caa tgg ggg cct      480
 Tyr Ser Lys Ile Leu Glu Ala Ser Ala Val Ile His Gln Trp Gly Pro
 145                 150                 155                 160

 acc aga ggc tcc aaa cag tat ccc tat ctg cca ctg aca cct caa gca      528
 Thr Arg Gly Ser Lys Gln Tyr Pro Tyr Leu Pro Leu Thr Pro Gln Ala
                 165                 170                 175

 cca ctg gat ctg ctg ggt cat atg gcc caa gtg gta gag cag ctt gca      576
 Pro Leu Asp Leu Leu Gly His Met Ala Gln Val Val Glu Gln Leu Ala
             180                 185                 190

 cag cag cct gga cct gtt gca gag cct tct cct gtt gtg gac ccc att      624
 Gln Gln Pro Gly Pro Val Ala Glu Pro Ser Pro Val Val Asp Pro Ile
         195                 200                 205

 caa aac tgg cag cct ttc agg tca ctc aat aaa tgg gcc aga gta aca      672
 Gln Asn Trp Gln Pro Phe Arg Ser Leu Asn Lys Trp Ala Arg Val Thr
     210                 215                 220

 cac cca aat gag gaa tgt gct gcc ttc aaa atc caa ata ggc cca cta      720
 His Pro Asn Glu Glu Cys Ala Ala Phe Lys Ile Gln Ile Gly Pro Leu
 225                 230                 235                 240

 ggc ttt gtg cct ctt tct tgg ttt ggg agg gac cta atg cag caa gtt      768
 Gly Phe Val Pro Leu Ser Trp Phe Gly Arg Asp Leu Met Gln Gln Val
                 245                 250                 255

 atc ctt cac ctt aga aag aat atc tca aca ggc ccc aca cca cta gac      816
 Ile Leu His Leu Arg Lys Asn Ile Ser Thr Gly Pro Thr Pro Leu Asp
             260                 265                 270

 ccc tag                                                              822
 Pro 






      <210> 889
      <211> 783
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(783)

      <400> 889
  atg gcc ggg cct ccg agg ctc ctg ctg ctg ccc ctg ctt ctg gcg ctg      48
  Met Ala Gly Pro Pro Arg Leu Leu Leu Leu Pro Leu Leu Leu Ala Leu
    1               5                  10                  15

 gct cgc ggc ctg cct ggg gcc ctg gct gcc caa gag gtg cag cag tct       96
 Ala Arg Gly Leu Pro Gly Ala Leu Ala Ala Gln Glu Val Gln Gln Ser
              20                  25                  30

 ccc cac tgc acg act gtc ccc gtg gga gcc tcc gtc aac atc acc tgc      144
 Pro His Cys Thr Thr Val Pro Val Gly Ala Ser Val Asn Ile Thr Cys
          35                  40                  45

 tcc acc agc ggg ggc ctg cgt ggg atc tac ctg agg cag ctc ggg cca      192
 Ser Thr Ser Gly Gly Leu Arg Gly Ile Tyr Leu Arg Gln Leu Gly Pro
      50                  55                  60

 cag ccc caa gac atc att tac tac gag gac ggg gtg gtg ccc act acg      240
 Gln Pro Gln Asp Ile Ile Tyr Tyr Glu Asp Gly Val Val Pro Thr Thr
  65                  70                  75                  80

 gac aga cgg ttc cgg ggc cgc atc gac ttc tca ggg tcc cag gac aac      288
 Asp Arg Arg Phe Arg Gly Arg Ile Asp Phe Ser Gly Ser Gln Asp Asn
                  85                  90                  95

 ctg act atc acc atg cac cgc ctg cag ctg tcg gac act ggc acc tac      336
 Leu Thr Ile Thr Met His Arg Leu Gln Leu Ser Asp Thr Gly Thr Tyr
             100                 105                 110

 acc tgc cag gcc atc acg gag gtc aat gtc tac ggc tcc ggc acc ctg      384
 Thr Cys Gln Ala Ile Thr Glu Val Asn Val Tyr Gly Ser Gly Thr Leu
         115                 120                 125

 gtc ctg gtg aca gga aca gtc cca agg atg gca cag atg ctc gga cgc      432
 Val Leu Val Thr Gly Thr Val Pro Arg Met Ala Gln Met Leu Gly Arg
     130                 135                 140

 ccc acc aag gcc tct gcc ctc cct gcc cca tcc gga cta ccg ccc tcc      480
 Pro Thr Lys Ala Ser Ala Leu Pro Ala Pro Ser Gly Leu Pro Pro Ser
 145                 150                 155                 160

 ctg acc cgc aga cag cct ctg ccc tcc ctg acc cgc cag cag cct ctg      528
 Leu Thr Arg Arg Gln Pro Leu Pro Ser Leu Thr Arg Gln Gln Pro Leu
                 165                 170                 175

 ccc tcc ctg cgg gcc tgg cgg ctc tgg aac tct cag ggt gga agt ggc      576
 Pro Ser Leu Arg Ala Trp Arg Leu Trp Asn Ser Gln Gly Gly Ser Gly
             180                 185                 190

 ctc ggc ggg gag gga ggg gga cca gca cca aag cga cct gag ggg gag      624
 Leu Gly Gly Glu Gly Gly Gly Pro Ala Pro Lys Arg Pro Glu Gly Glu
         195                 200                 205

 gga gca gcc cag gcg ctg ggc cgc gct gtg cgt gtg cgc gtg ctg cag      672
 Gly Ala Ala Gln Ala Leu Gly Arg Ala Val Arg Val Arg Val Leu Gln
     210                 215                 220

 ata aag aaa ctg tgc tcg tgg cgg gat aag aat tcg gcg gca tgt gtg      720
 Ile Lys Lys Leu Cys Ser Trp Arg Asp Lys Asn Ser Ala Ala Cys Val
 225                 230                 235                 240

 gtg tac gag gac atg tcg cac agc cgc tgc aac acg ctg tcc tcc ccc      768
 Val Tyr Glu Asp Met Ser His Ser Arg Cys Asn Thr Leu Ser Ser Pro
                 245                 250                 255

 aac cag tac cag tga                                                  783
 Asn Gln Tyr Gln 
             260





      <210> 890
      <211> 612
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(612)

      <400> 890
  atg ttc ggc agg gga atc aca caa aaa aga tgc cgg ttc ttg ctt gcc      48
  Met Phe Gly Arg Gly Ile Thr Gln Lys Arg Cys Arg Phe Leu Leu Ala
    1               5                  10                  15

 gta ttc atc aaa ctc ggt gct gca gga tcg tgt ggg gag gga gga gag       96
 Val Phe Ile Lys Leu Gly Ala Ala Gly Ser Cys Gly Glu Gly Gly Glu
              20                  25                  30

 tgt acc gcc agt gtt cag aaa gca gat aaa aat ctg gaa att gtc aga      144
 Cys Thr Ala Ser Val Gln Lys Ala Asp Lys Asn Leu Glu Ile Val Arg
          35                  40                  45

 aga tac aca ctg gct gat tgg tac cct ttc acc ttc act gtt caa ggt      192
 Arg Tyr Thr Leu Ala Asp Trp Tyr Pro Phe Thr Phe Thr Val Gln Gly
      50                  55                  60

 gga aca ata atc tct aag ata gta ggt aaa atg gct gtt tgg gga tac      240
 Gly Thr Ile Ile Ser Lys Ile Val Gly Lys Met Ala Val Trp Gly Tyr
  65                  70                  75                  80

 att gtg cat att ttg gta ata cac gga ata ttc act cag ttg agc cta      288
 Ile Val His Ile Leu Val Ile His Gly Ile Phe Thr Gln Leu Ser Leu
                  85                  90                  95

 atg gct ctt cga aag cca tta agg cgt act aag tgt ggt gtg aat gga      336
 Met Ala Leu Arg Lys Pro Leu Arg Arg Thr Lys Cys Gly Val Asn Gly
             100                 105                 110

 gaa cat gtg gcc cag cag ttg cca gag ggc acg ttt tct aag ctc aaa      384
 Glu His Val Ala Gln Gln Leu Pro Glu Gly Thr Phe Ser Lys Leu Lys
         115                 120                 125

 gtc aga ggc cat tgg gct gag act gcc aag ctt tgg aac atc aac ggg      432
 Val Arg Gly His Trp Ala Glu Thr Ala Lys Leu Trp Asn Ile Asn Gly
     130                 135                 140

 gat gta gtt gga aag gag tct ata cag acg atc aga gtg gtc atg cga      480
 Asp Val Val Gly Lys Glu Ser Ile Gln Thr Ile Arg Val Val Met Arg
 145                 150                 155                 160

 cac tac cct gct caa ttc aat gtc agc aaa gat tat tac atg ttg ctt      528
 His Tyr Pro Ala Gln Phe Asn Val Ser Lys Asp Tyr Tyr Met Leu Leu
                 165                 170                 175

 tca gga atg ctc ccc tta aag ggt ggc aga ttc agt tgg cag atg ccc      576
 Ser Gly Met Leu Pro Leu Lys Gly Gly Arg Phe Ser Trp Gln Met Pro
             180                 185                 190

 ttt gat tct gtg atc atc ctc ttc ctt tct acc tga                      612
 Phe Asp Ser Val Ile Ile Leu Phe Leu Ser Thr 
         195                 200





      <210> 891
      <211> 522
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(522)

      <400> 891
  atg ctg tgt gta ctc cgg caa gtt cct ttg cag gga ctg agc ctc cct      48
  Met Leu Cys Val Leu Arg Gln Val Pro Leu Gln Gly Leu Ser Leu Pro
    1               5                  10                  15

 ttc ctg ttt cca aca gac tgg aac aac tgc ctc ctg ctg cat ggg cga       96
 Phe Leu Phe Pro Thr Asp Trp Asn Asn Cys Leu Leu Leu His Gly Arg
              20                  25                  30

 aat acc tcg cgg acg tgt ctt acg gcg ccc cat gaa agc atc acc att      144
 Asn Thr Ser Arg Thr Cys Leu Thr Ala Pro His Glu Ser Ile Thr Ile
          35                  40                  45

 aat ctg acc agt cac cgc agc atg agt atc ttc agg gca cag atg aag      192
 Asn Leu Thr Ser His Arg Ser Met Ser Ile Phe Arg Ala Gln Met Lys
      50                  55                  60

 ccg tgg gca cca gtg ata agg agt tgc cac tgc tgg cta agt gcg gag      240
 Pro Trp Ala Pro Val Ile Arg Ser Cys His Cys Trp Leu Ser Ala Glu
  65                  70                  75                  80

 cct cac aca tct gtg gtc cgg aaa ccc acg ccc cac tcc aaa ccc tct      288
 Pro His Thr Ser Val Val Arg Lys Pro Thr Pro His Ser Lys Pro Ser
                  85                  90                  95

 aca gct cca aca gtt atg cta aca aga aaa agg agt gaa aac ccg ctc      336
 Thr Ala Pro Thr Val Met Leu Thr Arg Lys Arg Ser Glu Asn Pro Leu
             100                 105                 110

 cag tca cgg tat tgt gga ggt gga agg aca ctt gtg gca gcc aat cca      384
 Gln Ser Arg Tyr Cys Gly Gly Gly Arg Thr Leu Val Ala Ala Asn Pro
         115                 120                 125

 aca cct tca ttt tat agc cgg ggt aaa cgt agt tca gag agg ttg tcc      432
 Thr Pro Ser Phe Tyr Ser Arg Gly Lys Arg Ser Ser Glu Arg Leu Ser
     130                 135                 140

 cac ttg gtg aaa gtc aca cag cag ttc ctg ggc ggc aaa gtg agg aca      480
 His Leu Val Lys Val Thr Gln Gln Phe Leu Gly Gly Lys Val Arg Thr
 145                 150                 155                 160

 tcc agg tct cct aaa tct cac cct cgt gct ctg gcc act tga              522
 Ser Arg Ser Pro Lys Ser His Pro Arg Ala Leu Ala Thr 
                 165                 170





      <210> 892
      <211> 123
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(123)

      <400> 892
  atg tca act gtc gtc gtc tgc ata gtc ctg tgc ttc gtg gaa ttc tgg      48
  Met Ser Thr Val Val Val Cys Ile Val Leu Cys Phe Val Glu Phe Trp
    1               5                  10                  15

 ggc ttt ctt gct ggc cag gtc tgc ctt gtt acc cac aag tac agt gac       96
 Gly Phe Leu Ala Gly Gln Val Cys Leu Val Thr His Lys Tyr Ser Asp
              20                  25                  30

 aat gtt ggg gct ggc ctg cct ctc tag                                  123
 Asn Val Gly Ala Gly Leu Pro Leu 
          35                  40





      <210> 893
      <211> 369
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(369)

      <400> 893
  atg ggc tac ccg cac gca gcc act ctt gtt atc atg acc tgc ccg ctc      48
  Met Gly Tyr Pro His Ala Ala Thr Leu Val Ile Met Thr Cys Pro Leu
    1               5                  10                  15

 ctg agg agc ctg agg cta aca gct cag aac ctc aca ccc ccc aga gga       96
 Leu Arg Ser Leu Arg Leu Thr Ala Gln Asn Leu Thr Pro Pro Arg Gly
              20                  25                  30

 cct gct gtc ccc cac tgg tgc cgt cct gca gag tcg ggc cct gtc tcc      144
 Pro Ala Val Pro His Trp Cys Arg Pro Ala Glu Ser Gly Pro Val Ser
          35                  40                  45

 aga gcc tct ggt gtc cgc aca gcc atc gag ggc tca cca ctg cca cgc      192
 Arg Ala Ser Gly Val Arg Thr Ala Ile Glu Gly Ser Pro Leu Pro Arg
      50                  55                  60

 cag cca cgg gct cca aac gtt gaa gca gct ggc tgt ggg gtg cag gag      240
 Gln Pro Arg Ala Pro Asn Val Glu Ala Ala Gly Cys Gly Val Gln Glu
  65                  70                  75                  80

 tgc ccc ctg aca tct ctg ctg ctt ggc cgg gac ctc tca cca gac ctg      288
 Cys Pro Leu Thr Ser Leu Leu Leu Gly Arg Asp Leu Ser Pro Asp Leu
                  85                  90                  95

 gcc acc ggg cac aac ccg gcc agc ggc atg acc agc tgc cgc cac ctg      336
 Ala Thr Gly His Asn Pro Ala Ser Gly Met Thr Ser Cys Arg His Leu
             100                 105                 110

 cag att cag tgg ctg gag gtg gcc gca cag tga                          369
 Gln Ile Gln Trp Leu Glu Val Ala Ala Gln 
         115                 120





      <210> 894
      <211> 549
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(549)

      <400> 894
  atg ccc caa gtc cgg aaa cta aaa tat ctc ttg gtc tgg gta gac act      48
  Met Pro Gln Val Arg Lys Leu Lys Tyr Leu Leu Val Trp Val Asp Thr
    1               5                  10                  15

 ttc act gga tgg tta gag gcc ttt ccc aca ggg tct gag aag gcc acc       96
 Phe Thr Gly Trp Leu Glu Ala Phe Pro Thr Gly Ser Glu Lys Ala Thr
              20                  25                  30

 acg atc att tct tcc gtt ctg tca gac ata att cct tgg ttt ggc ctt      144
 Thr Ile Ile Ser Ser Val Leu Ser Asp Ile Ile Pro Trp Phe Gly Leu
          35                  40                  45

 ccc acc tct ata cag tcc aat aat aga ctg gcc ttt act agt caa atc      192
 Pro Thr Ser Ile Gln Ser Asn Asn Arg Leu Ala Phe Thr Ser Gln Ile
      50                  55                  60

 aca caa gca att tct cag gct ctt ggt att cag tgg aac ctt cat acc      240
 Thr Gln Ala Ile Ser Gln Ala Leu Gly Ile Gln Trp Asn Leu His Thr
  65                  70                  75                  80

 cct tac cgt cct caa tct tca gga aaa gta aaa cag act aat ggt ctt      288
 Pro Tyr Arg Pro Gln Ser Ser Gly Lys Val Lys Gln Thr Asn Gly Leu
                  85                  90                  95

 tta aag gta cac ctc acc aag ctc agc ctc caa ctt aaa aag gac tgg      336
 Leu Lys Val His Leu Thr Lys Leu Ser Leu Gln Leu Lys Lys Asp Trp
             100                 105                 110

 aca gta ctt tta cca ctt gcc ctt ctc aga att cgg gcc tgt cct cgg      384
 Thr Val Leu Leu Pro Leu Ala Leu Leu Arg Ile Arg Ala Cys Pro Arg
         115                 120                 125

 att gct aca ggg ccc tcg ttt ttg gtg gaa tca gct ttt acc agg aag      432
 Ile Ala Thr Gly Pro Ser Phe Leu Val Glu Ser Ala Phe Thr Arg Lys
     130                 135                 140

 gca cag ttg aaa tta aca cat cat ggt gac tat ggc tat gag ctg cct      480
 Ala Gln Leu Lys Leu Thr His His Gly Asp Tyr Gly Tyr Glu Leu Pro
 145                 150                 155                 160

 gtg act gct ttt gtc aga agg gag cat tgc aac aga gag cgg cat ggt      528
 Val Thr Ala Phe Val Arg Arg Glu His Cys Asn Arg Glu Arg His Gly
                 165                 170                 175

 gta gta gct gaa caa atg taa                                          549
 Val Val Ala Glu Gln Met 
             180





      <210> 895
      <211> 549
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(549)

      <400> 895
  atg aaa tca ggc ctg ctt ttt att ctg agg gtc ttg ctg tac ctt cct      48
  Met Lys Ser Gly Leu Leu Phe Ile Leu Arg Val Leu Leu Tyr Leu Pro
    1               5                  10                  15

 tac agc ttc tcc ctg gaa gag gcc tct cag tcc ata agc agt gac aac       96
 Tyr Ser Phe Ser Leu Glu Glu Ala Ser Gln Ser Ile Ser Ser Asp Asn
              20                  25                  30

 cag tta ccc cct caa aca gac act aca tgt cac tca gtg cct ggg cca      144
 Gln Leu Pro Pro Gln Thr Asp Thr Thr Cys His Ser Val Pro Gly Pro
          35                  40                  45

 tgt tgc ggc tct gcc ttt ggc cag tgc agg gct ctg tgg ccc gtg gca      192
 Cys Cys Gly Ser Ala Phe Gly Gln Cys Arg Ala Leu Trp Pro Val Ala
      50                  55                  60

 ctc cag cac ctg ggt cag ctg ctg ctg gca agt ggt ggg ccc tgt ctg      240
 Leu Gln His Leu Gly Gln Leu Leu Leu Ala Ser Gly Gly Pro Cys Leu
  65                  70                  75                  80

 cca gca cag ggc act cac aat att gga gct gag cca ggt aag cct ttc      288
 Pro Ala Gln Gly Thr His Asn Ile Gly Ala Glu Pro Gly Lys Pro Phe
                  85                  90                  95

 ctt gat cag att cct tcc agg aag cag agc acc atg gct tct gag agt      336
 Leu Asp Gln Ile Pro Ser Arg Lys Gln Ser Thr Met Ala Ser Glu Ser
             100                 105                 110

 aac tca aag gaa cgg cct aca gac agg gcc agg tta tta cac tac cta      384
 Asn Ser Lys Glu Arg Pro Thr Asp Arg Ala Arg Leu Leu His Tyr Leu
         115                 120                 125

 gat aag gga aga atc ata gac tgt gaa gtg tcc ctc cat atg gac cga      432
 Asp Lys Gly Arg Ile Ile Asp Cys Glu Val Ser Leu His Met Asp Arg
     130                 135                 140

 ctg cca ctg gaa agg aga gta gaa acg gaa aca gac ccg tct gga cag      480
 Leu Pro Leu Glu Arg Arg Val Glu Thr Glu Thr Asp Pro Ser Gly Gln
 145                 150                 155                 160

 aat cca aag tgc aaa cag gaa ctg tgc cca gag aga gga gga ggt ggc      528
 Asn Pro Lys Cys Lys Gln Glu Leu Cys Pro Glu Arg Gly Gly Gly Gly
                 165                 170                 175

 aga agc atg aag gct gct tag                                          549
 Arg Ser Met Lys Ala Ala 
             180





      <210> 896
      <211> 405
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(405)

      <400> 896
  atg cat ctc ccg gcg cag cct ggc gct ctg cgg gct ccg ctt ctg ctc      48
  Met His Leu Pro Ala Gln Pro Gly Ala Leu Arg Ala Pro Leu Leu Leu
    1               5                  10                  15

 aca ctg gca gcg ttg gtg cac gtg gga gtg cag tca cgg ggc tca cgt       96
 Thr Leu Ala Ala Leu Val His Val Gly Val Gln Ser Arg Gly Ser Arg
              20                  25                  30

 tcg cgt ttc ctc ggc tgc ctg gag ccc ata gag cgc tcc ttt ctg ggg      144
 Ser Arg Phe Leu Gly Cys Leu Glu Pro Ile Glu Arg Ser Phe Leu Gly
          35                  40                  45

 gaa gcc atc gca tct gtc ttg cca cag ggc acc tac ttt gga aga agc      192
 Glu Ala Ile Ala Ser Val Leu Pro Gln Gly Thr Tyr Phe Gly Arg Ser
      50                  55                  60

 agc aaa cag gaa atg gcc ctg aac tta gga agt gcc aca aac tgg tgc      240
 Ser Lys Gln Glu Met Ala Leu Asn Leu Gly Ser Ala Thr Asn Trp Cys
  65                  70                  75                  80

 aac aca tcg gat gat gac tgg ggt gac cac tgc aga cct tat gaa gtg      288
 Asn Thr Ser Asp Asp Asp Trp Gly Asp His Cys Arg Pro Tyr Glu Val
                  85                  90                  95

 cca cag act ggt gca aca cgt cgg atg atg act ggg gtg acc acc gca      336
 Pro Gln Thr Gly Ala Thr Arg Arg Met Met Thr Gly Val Thr Thr Ala
             100                 105                 110

 gat ctt atg aag tgc cat ctc ccg ctg acc atc ccc cac atg aag aac      384
 Asp Leu Met Lys Cys His Leu Pro Leu Thr Ile Pro His Met Lys Asn
         115                 120                 125

 tac ttg aaa ata aaa acg tag                                          405
 Tyr Leu Lys Ile Lys Thr 
     130





      <210> 897
      <211> 186
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(186)

      <400> 897
  atg tgg cag tgc ctc ttc ctt cta gtc ctc cag ccc agc agg aga agc      48
  Met Trp Gln Cys Leu Phe Leu Leu Val Leu Gln Pro Ser Arg Arg Ser
    1               5                  10                  15

 tcc tgc tgc cga atg ctc tcc tac tgc tct atc gcc acc acc aac tgc       96
 Ser Cys Cys Arg Met Leu Ser Tyr Cys Ser Ile Ala Thr Thr Asn Cys
              20                  25                  30

 agc gag cag gcg gaa gat tgc ggc ctc ttc cag tcc tct aag ctg ggc      144
 Ser Glu Gln Ala Glu Asp Cys Gly Leu Phe Gln Ser Ser Lys Leu Gly
          35                  40                  45

 aca gag ttg ctc ctc cac tcg aca cag aag agt ctg aaa tga              186
 Thr Glu Leu Leu Leu His Ser Thr Gln Lys Ser Leu Lys 
      50                  55                  60





      <210> 898
      <211> 243
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(243)

      <400> 898
  atg gtg tgc att cct tgt atc gtc att cca gtt ctg ctc tgg atc tac      48
  Met Val Cys Ile Pro Cys Ile Val Ile Pro Val Leu Leu Trp Ile Tyr
    1               5                  10                  15

 aaa aaa ttc ctg gag cca tat ata tac cct ctg gtt tcc ccc ttc gtt       96
 Lys Lys Phe Leu Glu Pro Tyr Ile Tyr Pro Leu Val Ser Pro Phe Val
              20                  25                  30

 agt cgt ata tgg cct aag aaa gca ata caa gaa tcc aat gat aca aac      144
 Ser Arg Ile Trp Pro Lys Lys Ala Ile Gln Glu Ser Asn Asp Thr Asn
          35                  40                  45

 aaa ggc aaa gta aac ttt aag gtt cct att cag ttt ctc ttg aga gga      192
 Lys Gly Lys Val Asn Phe Lys Val Pro Ile Gln Phe Leu Leu Arg Gly
      50                  55                  60

 atc ctt cag tct cct gcc ttg gag gca ggg aaa ctc act gtg gag ctg      240
 Ile Leu Gln Ser Pro Ala Leu Glu Ala Gly Lys Leu Thr Val Glu Leu
  65                  70                  75                  80

 tag                                                                  243
 






      <210> 899
      <211> 936
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(936)

      <400> 899
  atg aag ctg ttt cag ttt ttg aaa tta act aat tgg att ctc ccc aaa      48
  Met Lys Leu Phe Gln Phe Leu Lys Leu Thr Asn Trp Ile Leu Pro Lys
    1               5                  10                  15

 ata act aaa ttt aaa cca att aaa agt gct gag aat gtt ttt aca gaa       96
 Ile Thr Lys Phe Lys Pro Ile Lys Ser Ala Glu Asn Val Phe Thr Glu
              20                  25                  30

 ggg tct agt aat ggt aaa gct tct tat ttt gga tca aaa tgt aaa gtt      144
 Gly Ser Ser Asn Gly Lys Ala Ser Tyr Phe Gly Ser Lys Cys Lys Val
          35                  40                  45

 ttt cag acg ctc tat act tca gct caa aaa gca gag ctt gta gct gta      192
 Phe Gln Thr Leu Tyr Thr Ser Ala Gln Lys Ala Glu Leu Val Ala Val
      50                  55                  60

 att gag gta ttg act gct ttt gat atg cct att aat gtg att tct gat      240
 Ile Glu Val Leu Thr Ala Phe Asp Met Pro Ile Asn Val Ile Ser Asp
  65                  70                  75                  80

 tct tca tac gtg gtt cat tcc aca cag tta att gaa aat gct cag tta      288
 Ser Ser Tyr Val Val His Ser Thr Gln Leu Ile Glu Asn Ala Gln Leu
                  85                  90                  95

 cga ttt cat aca gaa gaa aaa ctg atg act tta ttt acc caa ttg caa      336
 Arg Phe His Thr Glu Glu Lys Leu Met Thr Leu Phe Thr Gln Leu Gln
             100                 105                 110

 aca gca gtt aga agt aga atg cac cga ttt tac atc act cac ata agg      384
 Thr Ala Val Arg Ser Arg Met His Arg Phe Tyr Ile Thr His Ile Arg
         115                 120                 125

 gct cat aca cat ctt cca gga tct ttg act gaa ggg aat caa atg gct      432
 Ala His Thr His Leu Pro Gly Ser Leu Thr Glu Gly Asn Gln Met Ala
     130                 135                 140

 gat cgc cta gtt gct act gca gta tct aat gct aga cac ttt cac agt      480
 Asp Arg Leu Val Ala Thr Ala Val Ser Asn Ala Arg His Phe His Ser
 145                 150                 155                 160

 tta acc cat gtt aat gcc tct ggt ctc aaa cac aga tac agc att acc      528
 Leu Thr His Val Asn Ala Ser Gly Leu Lys His Arg Tyr Ser Ile Thr
                 165                 170                 175

 tgg aaa gaa gct aaa gct att atc cag cga tgc cca act tgc caa gtg      576
 Trp Lys Glu Ala Lys Ala Ile Ile Gln Arg Cys Pro Thr Cys Gln Val
             180                 185                 190

 gag gag tta atc cta gag gac tgg aac cta act ctt ttg gca aat gga      624
 Glu Glu Leu Ile Leu Glu Asp Trp Asn Leu Thr Leu Leu Ala Asn Gly
         195                 200                 205

 tgt cac aca tgt tcc ctc gtt tgg gag act agc tta tgt aca tgc caa      672
 Cys His Thr Cys Ser Leu Val Trp Glu Thr Ser Leu Cys Thr Cys Gln
     210                 215                 220

 aat caa cag ctg att tgg ata cca tca aga cac ttg aaa cct tat cat      720
 Asn Gln Gln Leu Ile Trp Ile Pro Ser Arg His Leu Lys Pro Tyr His
 225                 230                 235                 240

 gag cca gat ccc aag gaa gag att cca gga gga tcc cga gga ccc ccc      768
 Glu Pro Asp Pro Lys Glu Glu Ile Pro Gly Gly Ser Arg Gly Pro Pro
                 245                 250                 255

 ccc ccc ccc cgc cat tgc ggc cat gtc gag gct gat gct aag gag gat      816
 Pro Pro Pro Arg His Cys Gly His Val Glu Ala Asp Ala Lys Glu Asp
             260                 265                 270

 ccc aac tgt cat gag caa cac ctg tcg agc aca gcc acc cac ctg ggg      864
 Pro Asn Cys His Glu Gln His Leu Ser Ser Thr Ala Thr His Leu Gly
         275                 280                 285

 gca gat caa gaa gct gtc aca gat ggt gga aga aaa cct gag gaa agc      912
 Ala Asp Gln Glu Ala Val Thr Asp Gly Gly Arg Lys Pro Glu Glu Ser
     290                 295                 300

 agg aca acc agt aac aat gag taa                                      936
 Arg Thr Thr Ser Asn Asn Glu 
 305                 310





      <210> 900
      <211> 420
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(420)

      <400> 900
  atg aca ggg ctc agc ctg ttg ctg ctt ccc ttg ctc ctg gtt caa gct      48
  Met Thr Gly Leu Ser Leu Leu Leu Leu Pro Leu Leu Leu Val Gln Ala
    1               5                  10                  15

 ggt gtc tgg gga ttc cca agg ccc cca ggg agg ccc cag ctg agc ctg       96
 Gly Val Trp Gly Phe Pro Arg Pro Pro Gly Arg Pro Gln Leu Ser Leu
              20                  25                  30

 cag gag ctg cgg agg gag ttc aca gtc agc ctg cat ctc gcc agg aag      144
 Gln Glu Leu Arg Arg Glu Phe Thr Val Ser Leu His Leu Ala Arg Lys
          35                  40                  45

 ctg ctc tcc gag gtt cgg ggc cag gcc cac cgc ttt gac ccg gag cgt      192
 Leu Leu Ser Glu Val Arg Gly Gln Ala His Arg Phe Asp Pro Glu Arg
      50                  55                  60

 ctc tgc ttc atc tcc acc acg ctt cag ccc ttc cat gcc ctg ctg gga      240
 Leu Cys Phe Ile Ser Thr Thr Leu Gln Pro Phe His Ala Leu Leu Gly
  65                  70                  75                  80

 ggg ctg ggg acc cag ggc cgc tgg acc aac atg gag agg atg cag ctg      288
 Gly Leu Gly Thr Gln Gly Arg Trp Thr Asn Met Glu Arg Met Gln Leu
                  85                  90                  95

 tgg gcc atg agg ctg gac ctc cgc gat ctg cag cgg cac ctc cgc ttc      336
 Trp Ala Met Arg Leu Asp Leu Arg Asp Leu Gln Arg His Leu Arg Phe
             100                 105                 110

 cag gta gag ccc ggc cac cct cca cca ccc cag acc acg tgg gaa aga      384
 Gln Val Glu Pro Gly His Pro Pro Pro Pro Gln Thr Thr Trp Glu Arg
         115                 120                 125

 aga ctc gct ggc tca ttc agt gat ccc atg ctc tga                      420
 Arg Leu Ala Gly Ser Phe Ser Asp Pro Met Leu 
     130                 135





      <210> 901
      <211> 957
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(957)

      <400> 901
  atg cat aaa gaa cta ccg aaa gtc aac aga gct att ccc att ctc ctt      48
  Met His Lys Glu Leu Pro Lys Val Asn Arg Ala Ile Pro Ile Leu Leu
    1               5                  10                  15

 ata ccc tac ttt ctg tta ttc agt aag ttc tgg ccc ttg gct gtg ctc       96
 Ile Pro Tyr Phe Leu Leu Phe Ser Lys Phe Trp Pro Leu Ala Val Leu
              20                  25                  30

 tcc tta gcc tgg ctc acc tat gat tgg aac acc cac agt caa ggt ggc      144
 Ser Leu Ala Trp Leu Thr Tyr Asp Trp Asn Thr His Ser Gln Gly Gly
          35                  40                  45

 agg cgt tca gct tgg gta cga aac tgg acc cta tgg aag tat ttc cga      192
 Arg Arg Ser Ala Trp Val Arg Asn Trp Thr Leu Trp Lys Tyr Phe Arg
      50                  55                  60

 aat tac ttc cca gta aag ctg gtg aag act cat gat ctt tct ccc aaa      240
 Asn Tyr Phe Pro Val Lys Leu Val Lys Thr His Asp Leu Ser Pro Lys
  65                  70                  75                  80

 cac aac tac atc att gcc aat cac ccc cat ggc att ctc tct ttt ggt      288
 His Asn Tyr Ile Ile Ala Asn His Pro His Gly Ile Leu Ser Phe Gly
                  85                  90                  95

 gtc ttc atc aac ttt gcc act gag gcc act ggc att gct cgg att ttc      336
 Val Phe Ile Asn Phe Ala Thr Glu Ala Thr Gly Ile Ala Arg Ile Phe
             100                 105                 110

 cca tcc atc act ccc ttt gta ggg acc tta gaa agg ata ttt tgg atc      384
 Pro Ser Ile Thr Pro Phe Val Gly Thr Leu Glu Arg Ile Phe Trp Ile
         115                 120                 125

 cca att gtg cga gaa tat gtg atg tca atg ggt gtg tgc cct gtg agt      432
 Pro Ile Val Arg Glu Tyr Val Met Ser Met Gly Val Cys Pro Val Ser
     130                 135                 140

 agc tca gcc ttg aag tac ttg ctg acc cag aaa ggc tca ggc aat gcc      480
 Ser Ser Ala Leu Lys Tyr Leu Leu Thr Gln Lys Gly Ser Gly Asn Ala
 145                 150                 155                 160

 gtg gtt att gtg gtg ggt gga gct gct gaa gct ctc ttg tgc cga cca      528
 Val Val Ile Val Val Gly Gly Ala Ala Glu Ala Leu Leu Cys Arg Pro
                 165                 170                 175

 gga gcc tcc act ctc ttc ctc aag cag cgt aaa ggt ttt gtg aag atg      576
 Gly Ala Ser Thr Leu Phe Leu Lys Gln Arg Lys Gly Phe Val Lys Met
             180                 185                 190

 gca ctg caa aca ggg gca tac ctt gtc cct tca tat tcc ttt ggt gag      624
 Ala Leu Gln Thr Gly Ala Tyr Leu Val Pro Ser Tyr Ser Phe Gly Glu
         195                 200                 205

 aac gaa gtt ttc aat cag gag acc ttc cct gag ggc acg tgg tta agg      672
 Asn Glu Val Phe Asn Gln Glu Thr Phe Pro Glu Gly Thr Trp Leu Arg
     210                 215                 220

 ttg ttc caa aaa acc ttc cag gac aca ttc aaa aaa atc ctg gga cta      720
 Leu Phe Gln Lys Thr Phe Gln Asp Thr Phe Lys Lys Ile Leu Gly Leu
 225                 230                 235                 240

 aat ttc tgt acc ttc cat ggc cgg ggc ttc act cgc gga tcc tgg ggc      768
 Asn Phe Cys Thr Phe His Gly Arg Gly Phe Thr Arg Gly Ser Trp Gly
                 245                 250                 255

 ttc ctg cct ttc aat cgg ccc att acc act gtt gtt ggg gaa ccc ctt      816
 Phe Leu Pro Phe Asn Arg Pro Ile Thr Thr Val Val Gly Glu Pro Leu
             260                 265                 270

 cca att ccc agg att aag agg cca aac cag aag aca gta gac aag tat      864
 Pro Ile Pro Arg Ile Lys Arg Pro Asn Gln Lys Thr Val Asp Lys Tyr
         275                 280                 285

 cac gca ctc tac atc agt gcc ctg cgc aag ctc ttt gac caa cac aaa      912
 His Ala Leu Tyr Ile Ser Ala Leu Arg Lys Leu Phe Asp Gln His Lys
     290                 295                 300

 gtt gaa tat ggc ctc cct gag acc caa gag ctg aca att aca taa          957
 Val Glu Tyr Gly Leu Pro Glu Thr Gln Glu Leu Thr Ile Thr 
 305                 310                 315





      <210> 902
      <211> 273
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(273)

      <400> 902
  atg tta aag gta ttg agt gcc tac tgg gtg tgg cca cac cct gtg ctg      48
  Met Leu Lys Val Leu Ser Ala Tyr Trp Val Trp Pro His Pro Val Leu
    1               5                  10                  15

 cga cac aga aat caa tct ggc aag ttc atg gtg ggg gtt gga ggg aag       96
 Arg His Arg Asn Gln Ser Gly Lys Phe Met Val Gly Val Gly Gly Lys
              20                  25                  30

 cag tcc ccg gca act gac aat ggt ggg gac aaa gca gat agt tct tct      144
 Gln Ser Pro Ala Thr Asp Asn Gly Gly Asp Lys Ala Asp Ser Ser Ser
          35                  40                  45

 agt gag cat cca aag gct ctg ggg aag ggt cag cat ggc att atg gtg      192
 Ser Glu His Pro Lys Ala Leu Gly Lys Gly Gln His Gly Ile Met Val
      50                  55                  60

 acc tcg gtt att ccc act ggc tgg cga caa gac ctg gtg gga gag gaa      240
 Thr Ser Val Ile Pro Thr Gly Trp Arg Gln Asp Leu Val Gly Glu Glu
  65                  70                  75                  80

 gct tcc agg atc tgg ggt cag aaa gga atg tga                          273
 Ala Ser Arg Ile Trp Gly Gln Lys Gly Met 
                  85                  90





      <210> 903
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 903
  atg aaa tgg ctc ctg att tac ctt cta agc ttc agc ata cct aag ctc      48
  Met Lys Trp Leu Leu Ile Tyr Leu Leu Ser Phe Ser Ile Pro Lys Leu
    1               5                  10                  15

 cat gct ttg gat aag tcc tcc agc aag tac ttt gtt gaa agc gag aaa       96
 His Ala Leu Asp Lys Ser Ser Ser Lys Tyr Phe Val Glu Ser Glu Lys
              20                  25                  30

 ggc agc tgc ata act ctc cag tcc aca gag ctg aca aat cac tgt gtc      144
 Gly Ser Cys Ile Thr Leu Gln Ser Thr Glu Leu Thr Asn His Cys Val
          35                  40                  45

 atc aaa gaa gag gga atc atg gga aat agc ctg tgg ttc acc ctc taa      192
 Ile Lys Glu Glu Gly Ile Met Gly Asn Ser Leu Trp Phe Thr Leu 
      50                  55                  60





      <210> 904
      <211> 222
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(222)

      <400> 904
  atg aag att tta ttt gta gaa cct gcc att ttc ctt agt gca ttt gct      48
  Met Lys Ile Leu Phe Val Glu Pro Ala Ile Phe Leu Ser Ala Phe Ala
    1               5                  10                  15

 atg act ttg acc ggt cca ctg aca acg caa tat gtt tat cgg aga ata       96
 Met Thr Leu Thr Gly Pro Leu Thr Thr Gln Tyr Val Tyr Arg Arg Ile
              20                  25                  30

 tgg gaa gaa act ggc aac tac act ttt tca tct gat agc aat att tct      144
 Trp Glu Glu Thr Gly Asn Tyr Thr Phe Ser Ser Asp Ser Asn Ile Ser
          35                  40                  45

 gag tgt gaa aaa aac aaa agc agc cca att ttt gca ttc cag gag ggc      192
 Glu Cys Glu Lys Asn Lys Ser Ser Pro Ile Phe Ala Phe Gln Glu Gly
      50                  55                  60

 ggc cat caa agt cct aaa tcc caa acc taa                              222
 Gly His Gln Ser Pro Lys Ser Gln Thr 
  65                  70





      <210> 905
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 905
  atg ggt ggg gag cgg cac ccc agt tat gtt ggc agg tcc ctg ccc ctg      48
  Met Gly Gly Glu Arg His Pro Ser Tyr Val Gly Arg Ser Leu Pro Leu
    1               5                  10                  15

 cta atg cct ctg ctt tgc ctc ttg cag aag cac aat ggt ggg gtt gag       96
 Leu Met Pro Leu Leu Cys Leu Leu Gln Lys His Asn Gly Gly Val Glu
              20                  25                  30

 ctc cgg gct gag tcc agc cct cat gag caa caa ccc ttt ggc cac tat      144
 Leu Arg Ala Glu Ser Ser Pro His Glu Gln Gln Pro Phe Gly His Tyr
          35                  40                  45

 cca agc gag acg gca gca cag acc cct gga ggt cca ggg ggg ccc gag      192
 Pro Ser Glu Thr Ala Ala Gln Thr Pro Gly Gly Pro Gly Gly Pro Glu
      50                  55                  60

 gca ggg tcc aaa cct gag tga                                          213
 Ala Gly Ser Lys Pro Glu 
  65                  70





      <210> 906
      <211> 159
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(159)

      <400> 906
  atg gtg atc acc act atc ata gct atc att aaa tta ctc att gtg act      48
  Met Val Ile Thr Thr Ile Ile Ala Ile Ile Lys Leu Leu Ile Val Thr
    1               5                  10                  15

 ggt tgt ccc act ttc ctt aga ttt tct tct gcc atc tgt gac agc ttc       96
 Gly Cys Pro Thr Phe Leu Arg Phe Ser Ser Ala Ile Cys Asp Ser Phe
              20                  25                  30

 ttg atc tgt ccc cag ctg gtt tct gta gat gct gtt cag ctg ctg ata      144
 Leu Ile Cys Pro Gln Leu Val Ser Val Asp Ala Val Gln Leu Leu Ile
          35                  40                  45

 gca tct ggc ctg tag                                                  159
 Ala Ser Gly Leu 
      50





      <210> 907
      <211> 165
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(165)

      <400> 907
  atg cgg ccc ctg ctc tgc gcg ctg acc gga ctg gcc ctg ctc cgc gcc      48
  Met Arg Pro Leu Leu Cys Ala Leu Thr Gly Leu Ala Leu Leu Arg Ala
    1               5                  10                  15

 gcg ggc tct ttg gcc gac aac tgc aga tgg ccc ctt ggc caa ccc atc       96
 Ala Gly Ser Leu Ala Asp Asn Cys Arg Trp Pro Leu Gly Gln Pro Ile
              20                  25                  30

 caa tac caa ggc ctt aca gct aca agc att gca cgt aga gag atc aag      144
 Gln Tyr Gln Gly Leu Thr Ala Thr Ser Ile Ala Arg Arg Glu Ile Lys
          35                  40                  45

 ttc cat aac tcc ccc tat tga                                          165
 Phe His Asn Ser Pro Tyr 
      50





      <210> 908
      <211> 219
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(219)

      <400> 908
  atg tgg cac ctc aaa ctt tgt gca gtc ctc atg atc ttc ctg ttg ctg      48
  Met Trp His Leu Lys Leu Cys Ala Val Leu Met Ile Phe Leu Leu Leu
    1               5                  10                  15

 ttg ggc cag aaa aag acg ctg ttc ctt aag tgt ggc cca gga atg atg       96
 Leu Gly Gln Lys Lys Thr Leu Phe Leu Lys Cys Gly Pro Gly Met Met
              20                  25                  30

 tac ata cca ggg aaa gaa agg aca gca gtc acc tcc gac aat gct ccg      144
 Tyr Ile Pro Gly Lys Glu Arg Thr Ala Val Thr Ser Asp Asn Ala Pro
          35                  40                  45

 ttc tat gga ata ttg att aac tgc att ttg gct gga gac acc caa gtg      192
 Phe Tyr Gly Ile Leu Ile Asn Cys Ile Leu Ala Gly Asp Thr Gln Val
      50                  55                  60

 aag caa tct tgt att ttt aat att taa                                  219
 Lys Gln Ser Cys Ile Phe Asn Ile 
  65                  70





      <210> 909
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 909
  atg gat aag act cgc tct gga aaa acc acc ttc gtg acc agg gta tct      48
  Met Asp Lys Thr Arg Ser Gly Lys Thr Thr Phe Val Thr Arg Val Ser
    1               5                  10                  15

 ctc ctg cca gcc ctc cta gcc ctg aca cac agc tgg gac tct cag gtc       96
 Leu Leu Pro Ala Leu Leu Ala Leu Thr His Ser Trp Asp Ser Gln Val
              20                  25                  30

 cga cca gcg gtc ctg aac ccg ctc cca cgg cac ggg aac tcc ttc gtg      144
 Arg Pro Ala Val Leu Asn Pro Leu Pro Arg His Gly Asn Ser Phe Val
          35                  40                  45

 gcg aag cag cat gtg gcg aag cag cag ccc ctg cgc tgg ctc atc tac      192
 Ala Lys Gln His Val Ala Lys Gln Gln Pro Leu Arg Trp Leu Ile Tyr
      50                  55                  60

 ata gaa gtc gcc cta tcc gtg atg tca ccg aca gtg cct ttc cca gtc      240
 Ile Glu Val Ala Leu Ser Val Met Ser Pro Thr Val Pro Phe Pro Val
  65                  70                  75                  80

 ccc gtc tgc ctt tct gcc gct cag ccg acc aac ccg ctg ccg gag ccg      288
 Pro Val Cys Leu Ser Ala Ala Gln Pro Thr Asn Pro Leu Pro Glu Pro
                  85                  90                  95

 gca agg gga agt gac gtc tgc ctc tcc ctt ttt tct ctc ctg ctt ccc      336
 Ala Arg Gly Ser Asp Val Cys Leu Ser Leu Phe Ser Leu Leu Leu Pro
             100                 105                 110

 tca tct gtt ctc ttc caa aga agc tgg tcc tta gcc tgt att gcg gag      384
 Ser Ser Val Leu Phe Gln Arg Ser Trp Ser Leu Ala Cys Ile Ala Glu
         115                 120                 125

 caa gct ttc ggc gac cag ctg gac cct ggg cac cct tct tcg aac aat      432
 Gln Ala Phe Gly Asp Gln Leu Asp Pro Gly His Pro Ser Ser Asn Asn
     130                 135                 140

 ggc ttt taa                                                          441
 Gly Phe 
 145





      <210> 910
      <211> 267
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(267)

      <400> 910
  atg aag aag att ccc ctt tct gcc atc acc ctg acc ttc ctg tct ggg      48
  Met Lys Lys Ile Pro Leu Ser Ala Ile Thr Leu Thr Phe Leu Ser Gly
    1               5                  10                  15

 atg ctg caa gag tat tta gtg gaa cta gct aga gtc ctt gct ggc atc       96
 Met Leu Gln Glu Tyr Leu Val Glu Leu Ala Arg Val Leu Ala Gly Ile
              20                  25                  30

 ctg gaa ggc ctg ccc cag ccg caa gcc att gga gaa cct ctg ttt atc      144
 Leu Glu Gly Leu Pro Gln Pro Gln Ala Ile Gly Glu Pro Leu Phe Ile
          35                  40                  45

 cgt tat tcc tta gct ttt gag agt cat ggt tct gtg ggg tca gag ttc      192
 Arg Tyr Ser Leu Ala Phe Glu Ser His Gly Ser Val Gly Ser Glu Phe
      50                  55                  60

 aga ctg ctg ttt cct aaa gga atg ttt gta gtt ccg agt cac ttt aaa      240
 Arg Leu Leu Phe Pro Lys Gly Met Phe Val Val Pro Ser His Phe Lys
  65                  70                  75                  80

 agt cct gtt cta aat cct gat tta tag                                  267
 Ser Pro Val Leu Asn Pro Asp Leu 
                  85





      <210> 911
      <211> 618
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(618)

      <400> 911
  atg gcc cag agc cgg gtg ctg ctg ctc ctg ctg ctg ctg ccg cca cag      48
  Met Ala Gln Ser Arg Val Leu Leu Leu Leu Leu Leu Leu Pro Pro Gln
    1               5                  10                  15

 ctg cac ctg gga cct gtg ctt gcc gtg agg gcc cca gga ttt ggc cga       96
 Leu His Leu Gly Pro Val Leu Ala Val Arg Ala Pro Gly Phe Gly Arg
              20                  25                  30

 agt ggc ggc cac agc ctg agc ccc gaa gag aac gaa ttt gcg gag gag      144
 Ser Gly Gly His Ser Leu Ser Pro Glu Glu Asn Glu Phe Ala Glu Glu
          35                  40                  45

 gag ccg gtg ctg gta ctg agc cct gag gag ccc ggg cct ggc cca gcc      192
 Glu Pro Val Leu Val Leu Ser Pro Glu Glu Pro Gly Pro Gly Pro Ala
      50                  55                  60

 gcg gtc agc tgc ccc cga gac tgt gcc tgt tcc cag gag ggc gtc gtg      240
 Ala Val Ser Cys Pro Arg Asp Cys Ala Cys Ser Gln Glu Gly Val Val
  65                  70                  75                  80

 gac tgt ggc ggt att gac ctg cgt gag ttc ccg ggg gac ctg cct gag      288
 Asp Cys Gly Gly Ile Asp Leu Arg Glu Phe Pro Gly Asp Leu Pro Glu
                  85                  90                  95

 cac acc aac cac cta tct ctg cag aac cct gac act cca agc aaa ctg      336
 His Thr Asn His Leu Ser Leu Gln Asn Pro Asp Thr Pro Ser Lys Leu
             100                 105                 110

 ttc acc cag aac ctc caa tat gtg cgg ctc tcc act ccc aac cac agg      384
 Phe Thr Gln Asn Leu Gln Tyr Val Arg Leu Ser Thr Pro Asn His Arg
         115                 120                 125

 gtg ctg ggg cag agc cca tat gca gac ctg gcc cag agc tgg cac cgg      432
 Val Leu Gly Gln Ser Pro Tyr Ala Asp Leu Ala Gln Ser Trp His Arg
     130                 135                 140

 ggg tct gct gcc atg ggg gag aat tcc aag gga ggt gcc cag cag gtg      480
 Gly Ser Ala Ala Met Gly Glu Asn Ser Lys Gly Gly Ala Gln Gln Val
 145                 150                 155                 160

 gac tgg att cta gga ctg gag cta tgg aac aac cag ctg gaa aag atc      528
 Asp Trp Ile Leu Gly Leu Glu Leu Trp Asn Asn Gln Leu Glu Lys Ile
                 165                 170                 175

 tac cct gag gag ctc tcc cgg ctg cac cgg ctg gag acg ctg aac ctg      576
 Tyr Pro Glu Glu Leu Ser Arg Leu His Arg Leu Glu Thr Leu Asn Leu
             180                 185                 190

 caa aac aac cgc ctg act tcc cga ggt cat ttg ttt agt tga              618
 Gln Asn Asn Arg Leu Thr Ser Arg Gly His Leu Phe Ser 
         195                 200                 205





      <210> 912
      <211> 663
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(663)

      <400> 912
  atg gtg tct ttc gtc ttc gtt tgt gta ttc tgt ccc tcc tgt cgt gtc      48
  Met Val Ser Phe Val Phe Val Cys Val Phe Cys Pro Ser Cys Arg Val
    1               5                  10                  15

 tat gtg tct cct gtt cgt tct gct gtt cgt tcg ttc gtt ctg ttc gtt       96
 Tyr Val Ser Pro Val Arg Ser Ala Val Arg Ser Phe Val Leu Phe Val
              20                  25                  30

 cgt cgt gtg tct tcg ttc gtg tgg ttc cgt ggg gcc ccc gcg aga ggt      144
 Arg Arg Val Ser Ser Phe Val Trp Phe Arg Gly Ala Pro Ala Arg Gly
          35                  40                  45

 cat gcg ggc gcc agg gcg ggg ccg ggc ccg gcg gtg gcg gcg gcg gcg      192
 His Ala Gly Ala Arg Ala Gly Pro Gly Pro Ala Val Ala Ala Ala Ala
      50                  55                  60

 ggc ggc agc ctg gtc ccc gcg gcg cgc cag caa cac tgc acg cag gtg      240
 Gly Gly Ser Leu Val Pro Ala Ala Arg Gln Gln His Cys Thr Gln Val
  65                  70                  75                  80

 cgc agc cgg cgg ctc atg aag gag ctg cag gac atc gcg cgc ctt agc      288
 Arg Ser Arg Arg Leu Met Lys Glu Leu Gln Asp Ile Ala Arg Leu Ser
                  85                  90                  95

 gac cgc ttc atc tcc gtg gag ctg gtg gac gag agc ctg ttc gac tgg      336
 Asp Arg Phe Ile Ser Val Glu Leu Val Asp Glu Ser Leu Phe Asp Trp
             100                 105                 110

 aac gtg aag ctg cac cag gtg gac aag gac tcg gtg ctg tgg cag gac      384
 Asn Val Lys Leu His Gln Val Asp Lys Asp Ser Val Leu Trp Gln Asp
         115                 120                 125

 atg aag gag acc aac acc gag ttc atc ctg ctc aac ctc acc ttc ccc      432
 Met Lys Glu Thr Asn Thr Glu Phe Ile Leu Leu Asn Leu Thr Phe Pro
     130                 135                 140

 gac aac ttc ccc ttc tcg ccg ccc ttc atg cgg gtg ctc agc ccg cgc      480
 Asp Asn Phe Pro Phe Ser Pro Pro Phe Met Arg Val Leu Ser Pro Arg
 145                 150                 155                 160

 ctg gag aac ggc tac gtg ctg gac ggc ggc gcc atc tgc atg gag ctg      528
 Leu Glu Asn Gly Tyr Val Leu Asp Gly Gly Ala Ile Cys Met Glu Leu
                 165                 170                 175

 ctc acg ccg cgc ggc tgg tcc agc gcc tac acc gtg gag gcc gtc atg      576
 Leu Thr Pro Arg Gly Trp Ser Ser Ala Tyr Thr Val Glu Ala Val Met
             180                 185                 190

 cgc cag ttc gca gcc agc ctg gtc aag ggc cag aga aga gct gct cag      624
 Arg Gln Phe Ala Ala Ser Leu Val Lys Gly Gln Arg Arg Ala Ala Gln
         195                 200                 205

 cca gcc atc cgc aaa aga ttc aca gaa cat cag gac taa                  663
 Pro Ala Ile Arg Lys Arg Phe Thr Glu His Gln Asp 
     210                 215                 220





      <210> 913
      <211> 1338
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1338)

      <400> 913
  atg gag gcg cta atg gcc cgg ggc gcg ctc acg ggt ccc ctg agg gcg      48
  Met Glu Ala Leu Met Ala Arg Gly Ala Leu Thr Gly Pro Leu Arg Ala
    1               5                  10                  15

 ctc tgt ctc ctg ggc tgc ctg ctg agc cac gcc gcc gcc gtg ccg tcg       96
 Leu Cys Leu Leu Gly Cys Leu Leu Ser His Ala Ala Ala Val Pro Ser
              20                  25                  30

 ccc atc atc aag ttc ccc ggc gat gtc gcc ccc aaa acg gac aaa gag      144
 Pro Ile Ile Lys Phe Pro Gly Asp Val Ala Pro Lys Thr Asp Lys Glu
          35                  40                  45

 ttg gca gtg caa tac ctg aac acc ttc tat ggc tgc ccc aag gag agc      192
 Leu Ala Val Gln Tyr Leu Asn Thr Phe Tyr Gly Cys Pro Lys Glu Ser
      50                  55                  60

 tgc aac ctg ttt gtg ctg aag gac aca cta aag aag atg cag aag ttc      240
 Cys Asn Leu Phe Val Leu Lys Asp Thr Leu Lys Lys Met Gln Lys Phe
  65                  70                  75                  80

 ttt gga ctg ccc cag aca ggt gat ctt gac cag aat acc atc gag acc      288
 Phe Gly Leu Pro Gln Thr Gly Asp Leu Asp Gln Asn Thr Ile Glu Thr
                  85                  90                  95

 atg cgg aag cca cgc tgc ggc aac cca gat gtg gcc aac tac aac ttc      336
 Met Arg Lys Pro Arg Cys Gly Asn Pro Asp Val Ala Asn Tyr Asn Phe
             100                 105                 110

 ttc cct cgc aag ccc aag tgg gac aag aac cag atc aca tac agg atc      384
 Phe Pro Arg Lys Pro Lys Trp Asp Lys Asn Gln Ile Thr Tyr Arg Ile
         115                 120                 125

 att ggc tac aca cct gat ctg gac cca gag aca gtg gat gat gcc ttt      432
 Ile Gly Tyr Thr Pro Asp Leu Asp Pro Glu Thr Val Asp Asp Ala Phe
     130                 135                 140

 gct cgt gcc ttc caa gtc tgg agc gat gtg acc cca ctg cgg ttt tct      480
 Ala Arg Ala Phe Gln Val Trp Ser Asp Val Thr Pro Leu Arg Phe Ser
 145                 150                 155                 160

 cga atc cat gat gga gag gca gac atc atg atc aac ttt ggc cgc tgg      528
 Arg Ile His Asp Gly Glu Ala Asp Ile Met Ile Asn Phe Gly Arg Trp
                 165                 170                 175

 ggt agg cag aag atg ggg cag aag agg ggc cag cag gga tca gtg ttg      576
 Gly Arg Gln Lys Met Gly Gln Lys Arg Gly Gln Gln Gly Ser Val Leu
             180                 185                 190

 aga cga ggg ggc act ggt gtt ggg gga gac tcc cat ttt gat gac gat      624
 Arg Arg Gly Gly Thr Gly Val Gly Gly Asp Ser His Phe Asp Asp Asp
         195                 200                 205

 gag cta tgg acc ttg gga gaa ggc caa gtg gtc cgt gtg aag tat ggg      672
 Glu Leu Trp Thr Leu Gly Glu Gly Gln Val Val Arg Val Lys Tyr Gly
     210                 215                 220

 aac gcc gat ggg gag tac tgc aag ttc ccc ttc ttg ttc aat ggc aag      720
 Asn Ala Asp Gly Glu Tyr Cys Lys Phe Pro Phe Leu Phe Asn Gly Lys
 225                 230                 235                 240

 gag tac aac agc tgc act gat acc ggc cgc agc gat ggc ttc ctc tgg      768
 Glu Tyr Asn Ser Cys Thr Asp Thr Gly Arg Ser Asp Gly Phe Leu Trp
                 245                 250                 255

 tgc tcc acc acc tac aac ttt gag aag gat ggc aag tac ggc ttc tgt      816
 Cys Ser Thr Thr Tyr Asn Phe Glu Lys Asp Gly Lys Tyr Gly Phe Cys
             260                 265                 270

 ccc cat gaa gcc ctg ttc acc atg ggc ggc aac gct gaa gga cag ccc      864
 Pro His Glu Ala Leu Phe Thr Met Gly Gly Asn Ala Glu Gly Gln Pro
         275                 280                 285

 tgc aag ttt cca ttc cgc ttc cag ggc aca tcc tat gac agc tgc acc      912
 Cys Lys Phe Pro Phe Arg Phe Gln Gly Thr Ser Tyr Asp Ser Cys Thr
     290                 295                 300

 act gag ggc cgc acg gat ggc tac cgc tgg tgc ggc acc act gag gac      960
 Thr Glu Gly Arg Thr Asp Gly Tyr Arg Trp Cys Gly Thr Thr Glu Asp
 305                 310                 315                 320

 tac gac cgc gac aag aag tat ggc ttc tgc cct gag acc gcc atg tcc     1008
 Tyr Asp Arg Asp Lys Lys Tyr Gly Phe Cys Pro Glu Thr Ala Met Ser
                 325                 330                 335

 act gtt ggt ggg aac tca gaa ggt gcc ccc tgt gtc ttc ccc ttc act     1056
 Thr Val Gly Gly Asn Ser Glu Gly Ala Pro Cys Val Phe Pro Phe Thr
             340                 345                 350

 ttc ctg ggc aac aaa tat gag agc tgc acc agc gcc ggc cgc agt gac     1104
 Phe Leu Gly Asn Lys Tyr Glu Ser Cys Thr Ser Ala Gly Arg Ser Asp
         355                 360                 365

 gga aag atg tgg tgt gcg acc aca gcc aac tac gat gat gac cgc aag     1152
 Gly Lys Met Trp Cys Ala Thr Thr Ala Asn Tyr Asp Asp Asp Arg Lys
     370                 375                 380

 tgg ggc ttc tgc cct gac caa gtc agc acc atc tgt tac cag ggt gta     1200
 Trp Gly Phe Cys Pro Asp Gln Val Ser Thr Ile Cys Tyr Gln Gly Val
 385                 390                 395                 400

 aat ggt ggg tcc tcg tca gtc ctg ggt gct gag gat gga gct gac tgg     1248
 Asn Gly Gly Ser Ser Ser Val Leu Gly Ala Glu Asp Gly Ala Asp Trp
                 405                 410                 415

 gac agc tct ctg ccc cct agg act cac aag ctc agg gga gag agt gac     1296
 Asp Ser Ser Leu Pro Pro Arg Thr His Lys Leu Arg Gly Glu Ser Asp
             420                 425                 430

 cag gag aca gct tgt gac ctt act atg tgc tca gtg cag tga             1338
 Gln Glu Thr Ala Cys Asp Leu Thr Met Cys Ser Val Gln 
         435                 440                 445





      <210> 914
      <211> 1056
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1056)

      <400> 914
  atg cgg ttt cac cat gtt ggt cgg gct ggt ctt gaa ctc ctg acc ctt      48
  Met Arg Phe His His Val Gly Arg Ala Gly Leu Glu Leu Leu Thr Leu
    1               5                  10                  15

 tcc cca gag gcc tgc tgg ggg ctt gct gcg cag ccg caa aca aaa agg       96
 Ser Pro Glu Ala Cys Trp Gly Leu Ala Ala Gln Pro Gln Thr Lys Arg
              20                  25                  30

 cct ctt tgt aga tcc tcc cct agg acg ctc cgg agg aaa cag ctc ccc      144
 Pro Leu Cys Arg Ser Ser Pro Arg Thr Leu Arg Arg Lys Gln Leu Pro
          35                  40                  45

 tcg aag cgg tat tca gca ttc acg gct gtc acc cag gag tcc ctg ctg      192
 Ser Lys Arg Tyr Ser Ala Phe Thr Ala Val Thr Gln Glu Ser Leu Leu
      50                  55                  60

 ggt gct ggg ccc agt gcc ggg agc tac aaa ggt ttg act ggg gct gga      240
 Gly Ala Gly Pro Ser Ala Gly Ser Tyr Lys Gly Leu Thr Gly Ala Gly
  65                  70                  75                  80

 gga gga ggg gca gcc aac agt gtc aga ata tgt gag gga ctg aga agc      288
 Gly Gly Gly Ala Ala Asn Ser Val Arg Ile Cys Glu Gly Leu Arg Ser
                  85                  90                  95

 tgt gaa atc atc gta ttt cag aat gtg agg tca gta att ctg agc ata      336
 Cys Glu Ile Ile Val Phe Gln Asn Val Arg Ser Val Ile Leu Ser Ile
             100                 105                 110

 aaa gta aca gct gca atg gaa tgc aag atg agg cac aca ggt gag gtg      384
 Lys Val Thr Ala Ala Met Glu Cys Lys Met Arg His Thr Gly Glu Val
         115                 120                 125

 gaa cga cat gac act ctc cct tct cgc ttc agc tct cat act gtc aac      432
 Glu Arg His Asp Thr Leu Pro Ser Arg Phe Ser Ser His Thr Val Asn
     130                 135                 140

 aat gtc cct ctc atg gat ttg act gtg ctc tat ggc agt tct atc ctg      480
 Asn Val Pro Leu Met Asp Leu Thr Val Leu Tyr Gly Ser Ser Ile Leu
 145                 150                 155                 160

 gag gaa gaa gtt ctc ctt att gaa aat aaa agg ctc ctc tca gat ctg      528
 Glu Glu Glu Val Leu Leu Ile Glu Asn Lys Arg Leu Leu Ser Asp Leu
                 165                 170                 175

 ctt tgc aaa cat agc ccg gtc tct tgc tca aga tcg gga aaa gtg gca      576
 Leu Cys Lys His Ser Pro Val Ser Cys Ser Arg Ser Gly Lys Val Ala
             180                 185                 190

 ttt ggt cat aag gca tca tta aaa cgg aaa gca gag gaa aaa tta gaa      624
 Phe Gly His Lys Ala Ser Leu Lys Arg Lys Ala Glu Glu Lys Leu Glu
         195                 200                 205

 agc tac gga aaa aag att cac atg atg aat aac caa gct gaa gaa aaa      672
 Ser Tyr Gly Lys Lys Ile His Met Met Asn Asn Gln Ala Glu Glu Lys
     210                 215                 220

 gct gca gac cag ttt cga atg cga ctt aaa aat aag caa gat gaa atg      720
 Ala Ala Asp Gln Phe Arg Met Arg Leu Lys Asn Lys Gln Asp Glu Met
 225                 230                 235                 240

 aag cta gaa gga gat cac aga aga agc cag caa gtc tgt caa caa ttg      768
 Lys Leu Glu Gly Asp His Arg Arg Ser Gln Gln Val Cys Gln Gln Leu
                 245                 250                 255

 gac acc cag aaa aat att cag gtt ccc agg gaa gca tgg tac tgg ttg      816
 Asp Thr Gln Lys Asn Ile Gln Val Pro Arg Glu Ala Trp Tyr Trp Leu
             260                 265                 270

 agg ctt gaa aag gag act gaa gat gaa gaa gaa aaa gaa cag gat gaa      864
 Arg Leu Glu Lys Glu Thr Glu Asp Glu Glu Glu Lys Glu Gln Asp Glu
         275                 280                 285

 gat gaa tat aag agt gaa gat tta agt gta ctg gaa aaa tta caa ata      912
 Asp Glu Tyr Lys Ser Glu Asp Leu Ser Val Leu Glu Lys Leu Gln Ile
     290                 295                 300

 ttg act agt tat tta aga gaa gaa ctt ctg tat agt att tgg tgt gga      960
 Leu Thr Ser Tyr Leu Arg Glu Glu Leu Leu Tyr Ser Ile Trp Cys Gly
 305                 310                 315                 320

 aca gcc tat gaa gat aaa gaa gac cta tct tca aat tgt cca gga cca     1008
 Thr Ala Tyr Glu Asp Lys Glu Asp Leu Ser Ser Asn Cys Pro Gly Pro
                 325                 330                 335

 act tcg cag atc atg act aag att att ccc aat aaa ctg gaa act tga     1056
 Thr Ser Gln Ile Met Thr Lys Ile Ile Pro Asn Lys Leu Glu Thr 
             340                 345                 350





      <210> 915
      <211> 231
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(231)

      <400> 915
  atg aaa tca agt atc cac aat ttc ctg tat ctg tgg ctc tgt gac ttt      48
  Met Lys Ser Ser Ile His Asn Phe Leu Tyr Leu Trp Leu Cys Asp Phe
    1               5                  10                  15

 gca gcc ttt gca cca aca ggt gta gtg cat ccc tgg tct gac ttg ctg       96
 Ala Ala Phe Ala Pro Thr Gly Val Val His Pro Trp Ser Asp Leu Leu
              20                  25                  30

 tgg cca ctt gct gca tgc aga agt gaa gag ccg agt ttt tgg aaa gag      144
 Trp Pro Leu Ala Ala Cys Arg Ser Glu Glu Pro Ser Phe Trp Lys Glu
          35                  40                  45

 ctg cta cac gca atg ggg act gtt ttc gtc ctc aac gtc cac tcc ttt      192
 Leu Leu His Ala Met Gly Thr Val Phe Val Leu Asn Val His Ser Phe
      50                  55                  60

 gtc act aac aag tgg agt cac acc aag aat aga aat taa                  231
 Val Thr Asn Lys Trp Ser His Thr Lys Asn Arg Asn 
  65                  70                  75





      <210> 916
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 916
  atg acc acg tgg agc ctc cgg cgg agg ccg gcc cgc acg ctg gga ctc      48
  Met Thr Thr Trp Ser Leu Arg Arg Arg Pro Ala Arg Thr Leu Gly Leu
    1               5                  10                  15

 ctg ctg ctg gtc gtc ttg ggc ttc ctg gtg ctc cgc agg ctg gac tgg       96
 Leu Leu Leu Val Val Leu Gly Phe Leu Val Leu Arg Arg Leu Asp Trp
              20                  25                  30

 agc acc ctg gtc cct ctg cgg ctc cgc cat cga cag ctg ggg ctg cag      144
 Ser Thr Leu Val Pro Leu Arg Leu Arg His Arg Gln Leu Gly Leu Gln
          35                  40                  45

 gcc aag ggc tgg aac ttc atg ctg gag gat tcc acc ttc tgg atc ttc      192
 Ala Lys Gly Trp Asn Phe Met Leu Glu Asp Ser Thr Phe Trp Ile Phe
      50                  55                  60

 ggg ggc tcc atc cac tat ttc cgt gtg ccc agg gag tac tgg agg gac      240
 Gly Gly Ser Ile His Tyr Phe Arg Val Pro Arg Glu Tyr Trp Arg Asp
  65                  70                  75                  80

 cgc ctg ctg aag atg aag gcc tgt ggc ttg aac acc ctc acc acc tat      288
 Arg Leu Leu Lys Met Lys Ala Cys Gly Leu Asn Thr Leu Thr Thr Tyr
                  85                  90                  95

 gtt ccg tgg aac ctg cat gag cca gaa aga ggc aaa ttt gac ttc tct      336
 Val Pro Trp Asn Leu His Glu Pro Glu Arg Gly Lys Phe Asp Phe Ser
             100                 105                 110

 ggg aac ctg gac ctg gag tat gtg gtg ttg ctg ctt ctg tga              378
 Gly Asn Leu Asp Leu Glu Tyr Val Val Leu Leu Leu Leu 
         115                 120                 125





      <210> 917
      <211> 855
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(855)

      <400> 917
  atg gtc agg gcc tat gct atg ctg gtt ctc atg tgc ctg ctg tct gga      48
  Met Val Arg Ala Tyr Ala Met Leu Val Leu Met Cys Leu Leu Ser Gly
    1               5                  10                  15

 gga gac ctg gtt tca ggg aaa gga gaa tcc gtc aat cag cca gga gcc       96
 Gly Asp Leu Val Ser Gly Lys Gly Glu Ser Val Asn Gln Pro Gly Ala
              20                  25                  30

 aga agt tgg cag cct cga gag ctg caa gct ttt gac ctg gtc ccc aag      144
 Arg Ser Trp Gln Pro Arg Glu Leu Gln Ala Phe Asp Leu Val Pro Lys
          35                  40                  45

 ggc tca gct tcc cac tat atg gga cta gag gtc ttt gac ctt cat ggg      192
 Gly Ser Ala Ser His Tyr Met Gly Leu Glu Val Phe Asp Leu His Gly
      50                  55                  60

 cac caa ggt caa gtc cag gga att ctc aag ctc aaa ggc aag gag ttc      240
 His Gln Gly Gln Val Gln Gly Ile Leu Lys Leu Lys Gly Lys Glu Phe
  65                  70                  75                  80

 tta aag gat tgc agg aaa tac aga cct gga gag aat aga atg act gtc      288
 Leu Lys Asp Cys Arg Lys Tyr Arg Pro Gly Glu Asn Arg Met Thr Val
                  85                  90                  95

 cgg ccc aag gca gtt aaa tat ata cag ctg agg gag gca gag gag ctg      336
 Arg Pro Lys Ala Val Lys Tyr Ile Gln Leu Arg Glu Ala Glu Glu Leu
             100                 105                 110

 ccg ggt gcc tgg gat atc ctg gca gct ctg ctc aaa atg atc tac gac      384
 Pro Gly Ala Trp Asp Ile Leu Ala Ala Leu Leu Lys Met Ile Tyr Asp
         115                 120                 125

 ttc atg aat tta ttt ggc tcc tcc tcg ggg cca ggg gac atg acg ggc      432
 Phe Met Asn Leu Phe Gly Ser Ser Ser Gly Pro Gly Asp Met Thr Gly
     130                 135                 140

 acg cca ggc gcc gtt gcc acc cgg gat ggc gag gcc ccc gag cgc tcc      480
 Thr Pro Gly Ala Val Ala Thr Arg Asp Gly Glu Ala Pro Glu Arg Ser
 145                 150                 155                 160

 ccg ccc tgc agt ccg agc tac gac ctc acg ggc aag ttg cct ggg gca      528
 Pro Pro Cys Ser Pro Ser Tyr Asp Leu Thr Gly Lys Leu Pro Gly Ala
                 165                 170                 175

 gaa gtg ttg atg gag aag tgg gtt aac ata gtg agc ggg cct ggg tct      576
 Glu Val Leu Met Glu Lys Trp Val Asn Ile Val Ser Gly Pro Gly Ser
             180                 185                 190

 gtc ttc ttg ggg aag ctt agc aag cag gag gag gtg gct gag aga ggg      624
 Val Phe Leu Gly Lys Leu Ser Lys Gln Glu Glu Val Ala Glu Arg Gly
         195                 200                 205

 aag aag gga ccc ggc cag aag acc atc ctg gtg ggt gac agt ggt gtg      672
 Lys Lys Gly Pro Gly Gln Lys Thr Ile Leu Val Gly Asp Ser Gly Val
     210                 215                 220

 gga aag acg tct ctg ctg gtt cag ttc gat cag ggc aag ttc atc ccc      720
 Gly Lys Thr Ser Leu Leu Val Gln Phe Asp Gln Gly Lys Phe Ile Pro
 225                 230                 235                 240

 ggc tcc ttc tcg gcc act gtg ggc atc gga ttc acg ccc tgt acc cat      768
 Gly Ser Phe Ser Ala Thr Val Gly Ile Gly Phe Thr Pro Cys Thr His
                 245                 250                 255

 aaa aag ctc ttg gca gac gag cag agt ggt gta gct gag aag gag aga      816
 Lys Lys Leu Leu Ala Asp Glu Gln Ser Gly Val Ala Glu Lys Glu Arg
             260                 265                 270

 aga gac aag cag ctg aac gtc aag agt gga agc aac tga                  855
 Arg Asp Lys Gln Leu Asn Val Lys Ser Gly Ser Asn 
         275                 280





      <210> 918
      <211> 1044
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1044)

      <400> 918
  atg ggc aag tca ctt aga cac tct ggc tgc tgc ctc agc tgg cca agt      48
  Met Gly Lys Ser Leu Arg His Ser Gly Cys Cys Leu Ser Trp Pro Ser
    1               5                  10                  15

 ccc act gtg ctg cta cct ccc tgg ctg aca gcg cta aca gca gat gca       96
 Pro Thr Val Leu Leu Pro Pro Trp Leu Thr Ala Leu Thr Ala Asp Ala
              20                  25                  30

 ggc ctt cct gtg gcc tgg gtg atg ctc ttc acc tat cac aga cgc ggc      144
 Gly Leu Pro Val Ala Trp Val Met Leu Phe Thr Tyr His Arg Arg Gly
          35                  40                  45

 cag caa ggc ctg tct gtc aca cag ctt caa cat gac aga gag gtc tcc      192
 Gln Gln Gly Leu Ser Val Thr Gln Leu Gln His Asp Arg Glu Val Ser
      50                  55                  60

 acg tct agg cag ccc tgg tcc cag gac acc acc aat gtc atg gac cac      240
 Thr Ser Arg Gln Pro Trp Ser Gln Asp Thr Thr Asn Val Met Asp His
  65                  70                  75                  80

 tgc ctg atg act cac aga gta gga gaa gtg gtg acc ggg gcc atc agg      288
 Cys Leu Met Thr His Arg Val Gly Glu Val Val Thr Gly Ala Ile Arg
                  85                  90                  95

 ccc acg ggt tca gga gcc acc aga cca gtg tct cca aga gtg gac agc      336
 Pro Thr Gly Ser Gly Ala Thr Arg Pro Val Ser Pro Arg Val Asp Ser
             100                 105                 110

 cct ctg ggc atg ggg aga cgg aga tgg caa ttt cca caa cct tcc ctg      384
 Pro Leu Gly Met Gly Arg Arg Arg Trp Gln Phe Pro Gln Pro Ser Leu
         115                 120                 125

 acg gaa aaa cgt gcg ggc gag cag gct gcc att ccg ggc gca caa ccc      432
 Thr Glu Lys Arg Ala Gly Glu Gln Ala Ala Ile Pro Gly Ala Gln Pro
     130                 135                 140

 cgc ggc aca cag cgg ggc gcc cgg ccc ggg ccc cgg cac cgc agc ggc      480
 Arg Gly Thr Gln Arg Gly Ala Arg Pro Gly Pro Arg His Arg Ser Gly
 145                 150                 155                 160

 ttc gac atc ccc agg ggc cgc gct agg tct cgg cag cgc cct gag ggg      528
 Phe Asp Ile Pro Arg Gly Arg Ala Arg Ser Arg Gln Arg Pro Glu Gly
                 165                 170                 175

 agg acg ggc ccc gcc atg ccg cgc ccc aac cgc cgg ccc cgc ttt acc      576
 Arg Thr Gly Pro Ala Met Pro Arg Pro Asn Arg Arg Pro Arg Phe Thr
             180                 185                 190

 tcc aga agc ccg gtg ccc gat gct cgg ccg aaa gcg gag agg ggc ccg      624
 Ser Arg Ser Pro Val Pro Asp Ala Arg Pro Lys Ala Glu Arg Gly Pro
         195                 200                 205

 ggt ccg gac agg cgc cgg cag aac aag acc ctc agc ccc gcg cgg ctt      672
 Gly Pro Asp Arg Arg Arg Gln Asn Lys Thr Leu Ser Pro Ala Arg Leu
     210                 215                 220

 tgc gcg cac aac gaa acc ccc caa ccc acc gcc cac ccc acc gcc cag      720
 Cys Ala His Asn Glu Thr Pro Gln Pro Thr Ala His Pro Thr Ala Gln
 225                 230                 235                 240

 agg ctt cta gga ctt gta gtc cgc ccg gtc acc ccc ccc acc aca acc      768
 Arg Leu Leu Gly Leu Val Val Arg Pro Val Thr Pro Pro Thr Thr Thr
                 245                 250                 255

 cgc tct gag agg ctg ggg act acg gtg ccc ggc atg cac cgc cca ggc      816
 Arg Ser Glu Arg Leu Gly Thr Thr Val Pro Gly Met His Arg Pro Gly
             260                 265                 270

 gcc gcg ggc ggg ggc ggg gag ggg gcg cca cgg tcc gag gtc acg ccc      864
 Ala Ala Gly Gly Gly Gly Glu Gly Ala Pro Arg Ser Glu Val Thr Pro
         275                 280                 285

 cga cct gag gag agc tgg cgc cca gac cct tcc ccc ggg gag gag ggc      912
 Arg Pro Glu Glu Ser Trp Arg Pro Asp Pro Ser Pro Gly Glu Glu Gly
     290                 295                 300

 tcc cgc gcg aag ccg tct ccg aat gcg tcc agt cga ctc acc gtc ccc      960
 Ser Arg Ala Lys Pro Ser Pro Asn Ala Ser Ser Arg Leu Thr Val Pro
 305                 310                 315                 320

 gca gcc ctg ggg cag cgg ccg caa cag cag gac cga acg cct cgg cag     1008
 Ala Ala Leu Gly Gln Arg Pro Gln Gln Gln Asp Arg Thr Pro Arg Gln
                 325                 330                 335

 ctg gca gtc gca ctt ctg tca caa gga ggc ggg tag                     1044
 Leu Ala Val Ala Leu Leu Ser Gln Gly Gly Gly 
             340                 345





      <210> 919
      <211> 681
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(681)

      <400> 919
  atg agg ggc tgg gcg cgg tgg ctg atg cct gta atc cca gca ctt tgg      48
  Met Arg Gly Trp Ala Arg Trp Leu Met Pro Val Ile Pro Ala Leu Trp
    1               5                  10                  15

 gag gct gag gca ggt gaa tca caa gga gac att ggt ggg gta aac ata       96
 Glu Ala Glu Ala Gly Glu Ser Gln Gly Asp Ile Gly Gly Val Asn Ile
              20                  25                  30

 caa aaa tgt gat tgc ctc act caa cca aga gcc tta gcc ata att aaa      144
 Gln Lys Cys Asp Cys Leu Thr Gln Pro Arg Ala Leu Ala Ile Ile Lys
          35                  40                  45

 aga tgt tca gat gga gct gta cag gaa tgt gat gct gga gaa cta gag      192
 Arg Cys Ser Asp Gly Ala Val Gln Glu Cys Asp Ala Gly Glu Leu Glu
      50                  55                  60

 caa cag agc cac att agc aca agc agg ccc acc gcg gtc tca cac aca      240
 Gln Gln Ser His Ile Ser Thr Ser Arg Pro Thr Ala Val Ser His Thr
  65                  70                  75                  80

 ctc gag cct tcc ttt gcc cag tct cac atg cat gac tgg gat cgc gga      288
 Leu Glu Pro Ser Phe Ala Gln Ser His Met His Asp Trp Asp Arg Gly
                  85                  90                  95

 ttt gtc ccc ttc cga ctc ccc atg ctg gtt cgg tcc cag acg ctc agg      336
 Phe Val Pro Phe Arg Leu Pro Met Leu Val Arg Ser Gln Thr Leu Arg
             100                 105                 110

 tgc cac att ggg gtg cgc tct ccc ggc tcc tcc aca cgc tac gca gct      384
 Cys His Ile Gly Val Arg Ser Pro Gly Ser Ser Thr Arg Tyr Ala Ala
         115                 120                 125

 gcc cgc ctc aag agc gtc tgc gtg ctt cca gcg tta agt gga att cca      432
 Ala Arg Leu Lys Ser Val Cys Val Leu Pro Ala Leu Ser Gly Ile Pro
     130                 135                 140

 agc agc ctc cgg ggc aca gtt agt ctg gtc act gcg gcc aga ctg ccg      480
 Ser Ser Leu Arg Gly Thr Val Ser Leu Val Thr Ala Ala Arg Leu Pro
 145                 150                 155                 160

 cct cag gac cca gag aac gca gca cac ttt agt tgg gcc cat cta tcc      528
 Pro Gln Asp Pro Glu Asn Ala Ala His Phe Ser Trp Ala His Leu Ser
                 165                 170                 175

 ccg gcg agg ctt gga cta cgt ttc cca gga gac cct gcg gtc cag tat      576
 Pro Ala Arg Leu Gly Leu Arg Phe Pro Gly Asp Pro Ala Val Gln Tyr
             180                 185                 190

 gtc tcc cga gga ggg gcg gaa gcc cgg gag ccg ccc tct gag gct ggg      624
 Val Ser Arg Gly Gly Ala Glu Ala Arg Glu Pro Pro Ser Glu Ala Gly
         195                 200                 205

 cgg ggt gaa aga aag ctt gcc cca gag gac tta aac agg caa gaa gga      672
 Arg Gly Glu Arg Lys Leu Ala Pro Glu Asp Leu Asn Arg Gln Glu Gly
     210                 215                 220

 ctt ggt taa                                                          681
 Leu Gly 
 225





      <210> 920
      <211> 267
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(267)

      <400> 920
  atg aag ctg tct gct ttc ctc gct gtt gct tct ctg aac att tgg aaa      48
  Met Lys Leu Ser Ala Phe Leu Ala Val Ala Ser Leu Asn Ile Trp Lys
    1               5                  10                  15

 aca act agt gaa gca gcg tta agt gtt gtt aat gaa aaa aca cag gct       96
 Thr Thr Ser Glu Ala Ala Leu Ser Val Val Asn Glu Lys Thr Gln Ala
              20                  25                  30

 gtt gtt aat gaa aaa aca cag gcg cct ctg gat tgt gat aac agt gct      144
 Val Val Asn Glu Lys Thr Gln Ala Pro Leu Asp Cys Asp Asn Ser Ala
          35                  40                  45

 gat agt ctc cga gtc ttt gct gac agc agt att ggg gag aat tgg acc      192
 Asp Ser Leu Arg Val Phe Ala Asp Ser Ser Ile Gly Glu Asn Trp Thr
      50                  55                  60

 ctt cag atg gtt tgt gac cca gat act tgg atg cgt ggg ccc agg tct      240
 Leu Gln Met Val Cys Asp Pro Asp Thr Trp Met Arg Gly Pro Arg Ser
  65                  70                  75                  80

 gtt gtt ttt cgg act cca ttt tgc taa                                  267
 Val Val Phe Arg Thr Pro Phe Cys 
                  85





      <210> 921
      <211> 603
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(603)

      <400> 921
  atg gaa aag gaa tta atc ttc tca ccc tgg cga gtt ttc ctg aaa cta      48
  Met Glu Lys Glu Leu Ile Phe Ser Pro Trp Arg Val Phe Leu Lys Leu
    1               5                  10                  15

 ctt atc ctt agc gtc agc gct gta aga ggt gga gcc gct cag tcc cgc       96
 Leu Ile Leu Ser Val Ser Ala Val Arg Gly Gly Ala Ala Gln Ser Arg
              20                  25                  30

 ggg tgg ctg cag aca gaa ggg gta gtg gac agt gtt gac ttg aat tgc      144
 Gly Trp Leu Gln Thr Glu Gly Val Val Asp Ser Val Asp Leu Asn Cys
          35                  40                  45

 tgt ccc tcg ttc caa gcc ttt cct gtg aat gaa ccc gaa aac act cga      192
 Cys Pro Ser Phe Gln Ala Phe Pro Val Asn Glu Pro Glu Asn Thr Arg
      50                  55                  60

 cag gtc gtg aat aat cgt ttt aat gag tgt gca aag cgt gcg acg gga      240
 Gln Val Val Asn Asn Arg Phe Asn Glu Cys Ala Lys Arg Ala Thr Gly
  65                  70                  75                  80

 cac act ttc ggt ccc ccg cca gag ctc cgg tgc ccc cga gtg acc gct      288
 His Thr Phe Gly Pro Pro Pro Glu Leu Arg Cys Pro Arg Val Thr Ala
                  85                  90                  95

 ttc tgc gat cgc gtc cgc cgg gac ccc gtc cct ctt tcc cct tca gtc      336
 Phe Cys Asp Arg Val Arg Arg Asp Pro Val Pro Leu Ser Pro Ser Val
             100                 105                 110

 ttc agg gag ggg gag gcg ctc cgc att agc ggg gca gtt cag caa ccc      384
 Phe Arg Glu Gly Glu Ala Leu Arg Ile Ser Gly Ala Val Gln Gln Pro
         115                 120                 125

 cga ccc cac ccg cgt ggc tcc agg ccc agg ggt ccg ttc act tcc ccg      432
 Arg Pro His Pro Arg Gly Ser Arg Pro Arg Gly Pro Phe Thr Ser Pro
     130                 135                 140

 tcc ggt ttg ggg gac gcc aat tcg cct aag aaa acc ctg gca gaa gag      480
 Ser Gly Leu Gly Asp Ala Asn Ser Pro Lys Lys Thr Leu Ala Glu Glu
 145                 150                 155                 160

 cgc gga ccc ttc act aca aac ctc acg tca ggg tta cag cca cat tta      528
 Arg Gly Pro Phe Thr Thr Asn Leu Thr Ser Gly Leu Gln Pro His Leu
                 165                 170                 175

 gga acc tct tcg gaa aag ctg aga aat cac tgt ttt gca aaa agc ctt      576
 Gly Thr Ser Ser Glu Lys Leu Arg Asn His Cys Phe Ala Lys Ser Leu
             180                 185                 190

 ctg tac tgt gat ggg gct ttg tgg tga                                  603
 Leu Tyr Cys Asp Gly Ala Leu Trp 
         195                 200





      <210> 922
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 922
  atg gct tcc tgc ctg ggg ctt ctc atc ctg tcc tct tgt ttg ctt gcc      48
  Met Ala Ser Cys Leu Gly Leu Leu Ile Leu Ser Ser Cys Leu Leu Ala
    1               5                  10                  15

 gac tgc agg ttc atc cca gag gcc tgg tcg gcc tgc aca gtc acc tgt       96
 Asp Cys Arg Phe Ile Pro Glu Ala Trp Ser Ala Cys Thr Val Thr Cys
              20                  25                  30

 ggt gtg ggg acc cag tcc gtg gct gac ctg cct att gac gag tgt gaa      144
 Gly Val Gly Thr Gln Ser Val Ala Asp Leu Pro Ile Asp Glu Cys Glu
          35                  40                  45

 ggg ccc aag cca gca tcc cag cgt gcc tgt tat gca ggc cca tgc agc      192
 Gly Pro Lys Pro Ala Ser Gln Arg Ala Cys Tyr Ala Gly Pro Cys Ser
      50                  55                  60

 ggg gaa att cct gag ttc aac cca gac gag aca gat ggg ctc ttt ggt      240
 Gly Glu Ile Pro Glu Phe Asn Pro Asp Glu Thr Asp Gly Leu Phe Gly
  65                  70                  75                  80

 ggc ctg cag gat ttc gac gag ctg tat gac tgg gag tat gag ggg ttc      288
 Gly Leu Gln Asp Phe Asp Glu Leu Tyr Asp Trp Glu Tyr Glu Gly Phe
                  85                  90                  95

 acc aag tgc tcc gag tcc tgt gga gga gtg gct ctc aga ctg tca gct      336
 Thr Lys Cys Ser Glu Ser Cys Gly Gly Val Ala Leu Arg Leu Ser Ala
             100                 105                 110

 gtg agt ggc cag tac aac aaa tgc ttt ggc ttt cag ttg tca ttc tga      384
 Val Ser Gly Gln Tyr Asn Lys Cys Phe Gly Phe Gln Leu Ser Phe 
         115                 120                 125





      <210> 923
      <211> 738
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(738)

      <400> 923
  atg ccc ctg gtt atc atc atc cat ttt ctg gct atg aat tgg att att      48
  Met Pro Leu Val Ile Ile Ile His Phe Leu Ala Met Asn Trp Ile Ile
    1               5                  10                  15

 cca ggt acc tca tca aag ccc act ctc ggg aag ggg tct tac gtt gta       96
 Pro Gly Thr Ser Ser Lys Pro Thr Leu Gly Lys Gly Ser Tyr Val Val
              20                  25                  30

 gcc gca tcg gat ttc aag ggc aga acc ttc aag gtc gtt ggg gcc agt      144
 Ala Ala Ser Asp Phe Lys Gly Arg Thr Phe Lys Val Val Gly Ala Ser
          35                  40                  45

 gcc cgt gtg gta ttt gtt ttt gct gag cgg ctc ttt gct gtg ctg cat      192
 Ala Arg Val Val Phe Val Phe Ala Glu Arg Leu Phe Ala Val Leu His
      50                  55                  60

 ctc ctc gcc tcc ttt gac ggg ccc cag gga ccc tcc cag ggg aaa tca      240
 Leu Leu Ala Ser Phe Asp Gly Pro Gln Gly Pro Ser Gln Gly Lys Ser
  65                  70                  75                  80

 cag gag agc ctt ggt atg tat tca gaa tcc ttc cag gcc ttt cat tcc      288
 Gln Glu Ser Leu Gly Met Tyr Ser Glu Ser Phe Gln Ala Phe His Ser
                  85                  90                  95

 aat gca gtc atc ttc ccc cca ccc tca tct aag ggc agc tcc aaa aca      336
 Asn Ala Val Ile Phe Pro Pro Pro Ser Ser Lys Gly Ser Ser Lys Thr
             100                 105                 110

 gac aac acc agc agg ctg agt gta cca aag aaa aca agg tcc atc gta      384
 Asp Asn Thr Ser Arg Leu Ser Val Pro Lys Lys Thr Arg Ser Ile Val
         115                 120                 125

 ttc aag tca agc cct ttg gtc tgg gtg gat cag cca tcg ccc ctt gat      432
 Phe Lys Ser Ser Pro Leu Val Trp Val Asp Gln Pro Ser Pro Leu Asp
     130                 135                 140

 ggc atg ggg act caa att cca cat ctc act gat tcc agg atg ggt ctg      480
 Gly Met Gly Thr Gln Ile Pro His Leu Thr Asp Ser Arg Met Gly Leu
 145                 150                 155                 160

 agg aaa ggc tgg gat gaa gcc gag gca gcc ctc tca gac gta ccc tgt      528
 Arg Lys Gly Trp Asp Glu Ala Glu Ala Ala Leu Ser Asp Val Pro Cys
                 165                 170                 175

 gtc caa ctc tcc tgt gac att ctt gag aag cgg ctg tct cag ctc agg      576
 Val Gln Leu Ser Cys Asp Ile Leu Glu Lys Arg Leu Ser Gln Leu Arg
             180                 185                 190

 tca cgc tcc agc ctg gaa ccc agg atc gcc ccc acc ttc cct gcc cac      624
 Ser Arg Ser Ser Leu Glu Pro Arg Ile Ala Pro Thr Phe Pro Ala His
         195                 200                 205

 ttc cag att cag ttt gag cca cct agg gcc tgt tct gcc ccc gaa gag      672
 Phe Gln Ile Gln Phe Glu Pro Pro Arg Ala Cys Ser Ala Pro Glu Glu
     210                 215                 220

 aga gaa cca gcc agc cca gtg ctg caa cga tgg aag tgt tct gtt ctg      720
 Arg Glu Pro Ala Ser Pro Val Leu Gln Arg Trp Lys Cys Ser Val Leu
 225                 230                 235                 240

 tac cgc cca gta cag tag                                              738
 Tyr Arg Pro Val Gln 
                 245





      <210> 924
      <211> 519
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(519)

      <400> 924
  atg gtt cac tgt tcg gga cct cca aga tgc ctt ttt ctg tat tcc gct      48
  Met Val His Cys Ser Gly Pro Pro Arg Cys Leu Phe Leu Tyr Ser Ala
    1               5                  10                  15

 gca ctc tct cag ttt ctc ttt gcc ttt gag gat ccc aca gac cac atg       96
 Ala Leu Ser Gln Phe Leu Phe Ala Phe Glu Asp Pro Thr Asp His Met
              20                  25                  30

 tcc caa ctt aca tgg atg gtc ttg ccc caa agg ttt agg gat agc ctt      144
 Ser Gln Leu Thr Trp Met Val Leu Pro Gln Arg Phe Arg Asp Ser Leu
          35                  40                  45

 cat ctg ttt ggt cag gca ctg gcc cac agt cta ggc cac ttc tcc agt      192
 His Leu Phe Gly Gln Ala Leu Ala His Ser Leu Gly His Phe Ser Ser
      50                  55                  60

 cca ggc act ctg atc ctt cag tat gtg gat gat tta ctt ctg gct acc      240
 Pro Gly Thr Leu Ile Leu Gln Tyr Val Asp Asp Leu Leu Leu Ala Thr
  65                  70                  75                  80

 agt tca gaa gcc tta tgc cag cag gct act gta gag ctc ttg aat ttt      288
 Ser Ser Glu Ala Leu Cys Gln Gln Ala Thr Val Glu Leu Leu Asn Phe
                  85                  90                  95

 cta gct aat caa ggt tct gct cgc caa ggg gtg cac aaa ccc gcc aag      336
 Leu Ala Asn Gln Gly Ser Ala Arg Gln Gly Val His Lys Pro Ala Lys
             100                 105                 110

 gca ctc tgc ctg tgt gca cag cat ccg gca gca gtc aca ggg gcc cca      384
 Ala Leu Cys Leu Cys Ala Gln His Pro Ala Ala Val Thr Gly Ala Pro
         115                 120                 125

 gaa gca cgt tgg caa caa ggt gag gct gcc cag tgt tca gca caa aaa      432
 Glu Ala Arg Trp Gln Gln Gly Glu Ala Ala Gln Cys Ser Ala Gln Lys
     130                 135                 140

 aag aat tca gct gtg aca gct gag cag agc tca aca gcc atc tca gag      480
 Lys Asn Ser Ala Val Thr Ala Glu Gln Ser Ser Thr Ala Ile Ser Glu
 145                 150                 155                 160

 cac aag gac tgt gga aaa gct tca aat ccc acc tgc taa                  519
 His Lys Asp Cys Gly Lys Ala Ser Asn Pro Thr Cys 
                 165                 170





      <210> 925
      <211> 627
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(627)

      <400> 925
  atg aaa aga atc ctg tgg aaa tct ata cga atg ata gtg tgt gga tgc      48
  Met Lys Arg Ile Leu Trp Lys Ser Ile Arg Met Ile Val Cys Gly Cys
    1               5                  10                  15

 ctg gag cta cag atg acc att gcc cca ctc aac cag aag gcg gca cta       96
 Leu Glu Leu Gln Met Thr Ile Ala Pro Leu Asn Gln Lys Ala Ala Leu
              20                  25                  30

 cat tta atg tta cta tgg gtt ata aaa ccc tct ctg ggc ttg tac aac      144
 His Leu Met Leu Leu Trp Val Ile Lys Pro Ser Leu Gly Leu Tyr Asn
          35                  40                  45

 act ggt tgt aac cat cta aaa tca ggg aga ggc att aac cca cag tta      192
 Thr Gly Cys Asn His Leu Lys Ser Gly Arg Gly Ile Asn Pro Gln Leu
      50                  55                  60

 agg cta gaa aaa gag aaa gca gaa tgg ttc atg gtt ctg gac ctc aag      240
 Arg Leu Glu Lys Glu Lys Ala Glu Trp Phe Met Val Leu Asp Leu Lys
  65                  70                  75                  80

 gat gcc ttc ttc tgt att tcc ctg cac tct gac tcc cag ttt ctc ttt      288
 Asp Ala Phe Phe Cys Ile Ser Leu His Ser Asp Ser Gln Phe Leu Phe
                  85                  90                  95

 gac ttt gag gat ccc aca gac cac aca tcc caa ctt acg tgg acg gtc      336
 Asp Phe Glu Asp Pro Thr Asp His Thr Ser Gln Leu Thr Trp Thr Val
             100                 105                 110

 ttg ccc caa ggg ttt agg gat agc cct cat ctg ttt ggt cag gca ctg      384
 Leu Pro Gln Gly Phe Arg Asp Ser Pro His Leu Phe Gly Gln Ala Leu
         115                 120                 125

 gcc caa gat cta ggc cac ttc tca agt cca gac act ctg gtc ctt cag      432
 Ala Gln Asp Leu Gly His Phe Ser Ser Pro Asp Thr Leu Val Leu Gln
     130                 135                 140

 tat gtg gat gat tta cat ttg gct acc agt ttg gaa gcc tca tgc cag      480
 Tyr Val Asp Asp Leu His Leu Ala Thr Ser Leu Glu Ala Ser Cys Gln
 145                 150                 155                 160

 cag gct act cta gat ctc ttg aac ttt cta gct aat caa gag tac atg      528
 Gln Ala Thr Leu Asp Leu Leu Asn Phe Leu Ala Asn Gln Glu Tyr Met
                 165                 170                 175

 atg tct agg ttg agg gcc ccg ctt tgc cta gag caa gtc gaa tat cta      576
 Met Ser Arg Leu Arg Ala Pro Leu Cys Leu Glu Gln Val Glu Tyr Leu
             180                 185                 190

 gcc cta atc tta gcc aga ggg act agg gcc atc agc aag gaa caa ata      624
 Ala Leu Ile Leu Ala Arg Gly Thr Arg Ala Ile Ser Lys Glu Gln Ile
         195                 200                 205

 tag                                                                  627
 






      <210> 926
      <211> 378
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(378)

      <400> 926
  atg agc cta gtg tgc cta att gga ttt tgg agg caa cac att cct cat      48
  Met Ser Leu Val Cys Leu Ile Gly Phe Trp Arg Gln His Ile Pro His
    1               5                  10                  15

 ttg ggt gtg tta ctc cag ccc att tat cga atg acc caa aaa gct gcc       96
 Leu Gly Val Leu Leu Gln Pro Ile Tyr Arg Met Thr Gln Lys Ala Ala
              20                  25                  30

 agt ttt gag tgg ggt cta gaa cag gag aag tct ctg caa cag gtc cag      144
 Ser Phe Glu Trp Gly Leu Glu Gln Glu Lys Ser Leu Gln Gln Val Gln
          35                  40                  45

 gct gct gtg caa gct gct ctg cca ctt ggg cta tat gac ata gca gag      192
 Ala Ala Val Gln Ala Ala Leu Pro Leu Gly Leu Tyr Asp Ile Ala Glu
      50                  55                  60

 cca atg gtg ctt gag gtg cca gtg gca gat agg gat gct gtt tgt agc      240
 Pro Met Val Leu Glu Val Pro Val Ala Asp Arg Asp Ala Val Cys Ser
  65                  70                  75                  80

 ctt tgg cag gcc ccc ata ggt aac tac tct cct ttt gag aga cag ctc      288
 Leu Trp Gln Ala Pro Ile Gly Asn Tyr Ser Pro Phe Glu Arg Gln Leu
                  85                  90                  95

 ttg gcc tgt tac tgg gct ttg gta gaa act gaa cgt ttg act atg ggt      336
 Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Glu Arg Leu Thr Met Gly
             100                 105                 110

 cat caa gtc acc atg caa cct gaa ctg cct atc atg aac tga              378
 His Gln Val Thr Met Gln Pro Glu Leu Pro Ile Met Asn 
         115                 120                 125





      <210> 927
      <211> 1389
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1389)

      <400> 927
  atg tgg cac ttc atc atc tta ttt caa gaa act gcc aca gcc acc tta      48
  Met Trp His Phe Ile Ile Leu Phe Gln Glu Thr Ala Thr Ala Thr Leu
    1               5                  10                  15

 acc acc tcc ctg ctc aat cag caa cca tca aca tcc agg ctc ttt cag       96
 Thr Thr Ser Leu Leu Asn Gln Gln Pro Ser Thr Ser Arg Leu Phe Gln
              20                  25                  30

 gct tgt gtc gtt ttt atc ctt cca gtg tca gct tac aat gtc acc ttc      144
 Ala Cys Val Val Phe Ile Leu Pro Val Ser Ala Tyr Asn Val Thr Phe
          35                  40                  45

 tca gtg acc att gtt cta agg cct atc cgg gga gtg aat cct ctc agc      192
 Ser Val Thr Ile Val Leu Arg Pro Ile Arg Gly Val Asn Pro Leu Ser
      50                  55                  60

 tgc aag tct ggg acg gga ctt cat cct act aga gcc cta gct gat tgc      240
 Cys Lys Ser Gly Thr Gly Leu His Pro Thr Arg Ala Leu Ala Asp Cys
  65                  70                  75                  80

 ttg ata gtt ctt tgg ttt aca cca cag ttg aca tcc ata aca gga atg      288
 Leu Ile Val Leu Trp Phe Thr Pro Gln Leu Thr Ser Ile Thr Gly Met
                  85                  90                  95

 tct gac tta aag att cat ttg tta ctg gtc aat gca tct aac att gag      336
 Ser Asp Leu Lys Ile His Leu Leu Leu Val Asn Ala Ser Asn Ile Glu
             100                 105                 110

 ttt tac gga aaa ccc ctg ata ctt aat gac aga gag aag tat tct ctg      384
 Phe Tyr Gly Lys Pro Leu Ile Leu Asn Asp Arg Glu Lys Tyr Ser Leu
         115                 120                 125

 act ttt ctg agt gag tca aat acc act atg gaa gta ggt tat gaa ata      432
 Thr Phe Leu Ser Glu Ser Asn Thr Thr Met Glu Val Gly Tyr Glu Ile
     130                 135                 140

 gat tta gag agt tat gag cag aac ttt ttt aaa agg gaa ata gaa tgg      480
 Asp Leu Glu Ser Tyr Glu Gln Asn Phe Phe Lys Arg Glu Ile Glu Trp
 145                 150                 155                 160

 aat aga aaa tcc tgg tgg tca gaa gag gcc cat ttg cag gct cag cta      528
 Asn Arg Lys Ser Trp Trp Ser Glu Glu Ala His Leu Gln Ala Gln Leu
                 165                 170                 175

 aat cgg act aat ggc att cta att act cag gct caa ctc aca ggc tcc      576
 Asn Arg Thr Asn Gly Ile Leu Ile Thr Gln Ala Gln Leu Thr Gly Ser
             180                 185                 190

 gat agt ttc tct aat act tat gcc caa tta ggc ttt gat gct ctt acc      624
 Asp Ser Phe Ser Asn Thr Tyr Ala Gln Leu Gly Phe Asp Ala Leu Thr
         195                 200                 205

 aca aaa caa gca aca aag ttg tgt atg aga gct tac aat aaa tta cgt      672
 Thr Lys Gln Ala Thr Lys Leu Cys Met Arg Ala Tyr Asn Lys Leu Arg
     210                 215                 220

 gcc cca ggc caa cct tct gct tct ttt act act gtt aaa caa gct caa      720
 Ala Pro Gly Gln Pro Ser Ala Ser Phe Thr Thr Val Lys Gln Ala Gln
 225                 230                 235                 240

 ttg ctt tta tta cct aat atc att tta aac aaa gga ggt aag aca cgt      768
 Leu Leu Leu Leu Pro Asn Ile Ile Leu Asn Lys Gly Gly Lys Thr Arg
                 245                 250                 255

 ggc cct agg atg ggc tct gat ggt gaa aaa gcc gct tat tgg att aat      816
 Gly Pro Arg Met Gly Ser Asp Gly Glu Lys Ala Ala Tyr Trp Ile Asn
             260                 265                 270

 gta att tct aaa caa tgg ccc acc tac acc ata cac att caa gta aaa      864
 Val Ile Ser Lys Gln Trp Pro Thr Tyr Thr Ile His Ile Gln Val Lys
         275                 280                 285

 aag ttt gag ggc cta gtt gat act ggg gct gaa att aat att cca cat      912
 Lys Phe Glu Gly Leu Val Asp Thr Gly Ala Glu Ile Asn Ile Pro His
     290                 295                 300

 aac tct tat agt gct ccc agt cag cat acg atg gaa aac atg ggg ttt      960
 Asn Ser Tyr Ser Ala Pro Ser Gln His Thr Met Glu Asn Met Gly Phe
 305                 310                 315                 320

 gtt cct ggg ctt ggt ctc agt cca aag cat gaa ggg att act aaa tcc     1008
 Val Pro Gly Leu Gly Leu Ser Pro Lys His Glu Gly Ile Thr Lys Ser
                 325                 330                 335

 ctt cca gtt act gta aaa gaa aac agg gca gtt tcc tcc cac act gat     1056
 Leu Pro Val Thr Val Lys Glu Asn Arg Ala Val Ser Ser His Thr Asp
             340                 345                 350

 tta cct gct aca caa aat tat tct tac tgg gct tat gtg cct ttt cct     1104
 Leu Pro Ala Thr Gln Asn Tyr Ser Tyr Trp Ala Tyr Val Pro Phe Pro
         355                 360                 365

 cca ctt att cga cct ctc acc tgg ata gat gct cct gca gaa atc tac     1152
 Pro Leu Ile Arg Pro Leu Thr Trp Ile Asp Ala Pro Ala Glu Ile Tyr
     370                 375                 380

 act aac gat agt gtg tgg atg cct gga gcc aca gat gac tgt tgc cct     1200
 Thr Asn Asp Ser Val Trp Met Pro Gly Ala Thr Asp Asp Cys Cys Pro
 385                 390                 395                 400

 gct caa cca gga gaa ggc act gca ttt aat gtt acc atg ggt tat aaa     1248
 Ala Gln Pro Gly Glu Gly Thr Ala Phe Asn Val Thr Met Gly Tyr Lys
                 405                 410                 415

 tac cct cct ctg tgc ctt gga cat gca cct ggt tgt atc cat cta gaa     1296
 Tyr Pro Pro Leu Cys Leu Gly His Ala Pro Gly Cys Ile His Leu Glu
             420                 425                 430

 act caa gtc tgg gct gct tat ctt ccg gag ata tca gct aca gag gaa     1344
 Thr Gln Val Trp Ala Ala Tyr Leu Pro Glu Ile Ser Ala Thr Glu Glu
         435                 440                 445

 ccg gga tat ttg atc tct ggc ctc tcc ctt tct cct tta aaa taa         1389
 Pro Gly Tyr Leu Ile Ser Gly Leu Ser Leu Ser Pro Leu Lys 
     450                 455                 460





      <210> 928
      <211> 789
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(789)

      <400> 928
  atg aag ttc ttg gca gca gtg ctt ttc ccc ttc tgc ttt cca aaa gga      48
  Met Lys Phe Leu Ala Ala Val Leu Phe Pro Phe Cys Phe Pro Lys Gly
    1               5                  10                  15

 ggt aaa aag aag cca gtc aat ttc aaa aac ccc tat cct gct ttt att       96
 Gly Lys Lys Lys Pro Val Asn Phe Lys Asn Pro Tyr Pro Ala Phe Ile
              20                  25                  30

 ttc agc tac ctt gaa agt gag ctg aat cac cat gga aat gtg caa att      144
 Phe Ser Tyr Leu Glu Ser Glu Leu Asn His His Gly Asn Val Gln Ile
          35                  40                  45

 ttc ttt tcc tct tca ctc aaa gtt cag tgg agc tat ctc aag aga ttc      192
 Phe Phe Ser Ser Ser Leu Lys Val Gln Trp Ser Tyr Leu Lys Arg Phe
      50                  55                  60

 agt tac cag aaa ggt gga atc tgg atg agt gga ggt gag gag aag gtt      240
 Ser Tyr Gln Lys Gly Gly Ile Trp Met Ser Gly Gly Glu Glu Lys Val
  65                  70                  75                  80

 caa act ctc cac cag acc cat gct gca gct aag aag ccc cag agc gta      288
 Gln Thr Leu His Gln Thr His Ala Ala Ala Lys Lys Pro Gln Ser Val
                  85                  90                  95

 ggg ata tgc gta cgg cag aaa ggg aga cag aag gca ggg cta gag aaa      336
 Gly Ile Cys Val Arg Gln Lys Gly Arg Gln Lys Ala Gly Leu Glu Lys
             100                 105                 110

 ggg aac agg aaa aaa gag ctt cga caa gcc aac tgc cct tcg ctc agg      384
 Gly Asn Arg Lys Lys Glu Leu Arg Gln Ala Asn Cys Pro Ser Leu Arg
         115                 120                 125

 ccc cag cgg aaa ggc gca gat acc cgg aga ctt ccc aga gag act cga      432
 Pro Gln Arg Lys Gly Ala Asp Thr Arg Arg Leu Pro Arg Glu Thr Arg
     130                 135                 140

 ccc acc aaa aag cgc acc gcg gcc gcg cag ccc ttc ctt cag ctc tgg      480
 Pro Thr Lys Lys Arg Thr Ala Ala Ala Gln Pro Phe Leu Gln Leu Trp
 145                 150                 155                 160

 aac cca gcg ccc cac acc tca aat ggg aga act gac tcc aca gcc atc      528
 Asn Pro Ala Pro His Thr Ser Asn Gly Arg Thr Asp Ser Thr Ala Ile
                 165                 170                 175

 agg acg cct gcc aga gcc aag gat ccc atc aca gcc ggg gct ctg gag      576
 Arg Thr Pro Ala Arg Ala Lys Asp Pro Ile Thr Ala Gly Ala Leu Glu
             180                 185                 190

 aga gtg agc cag acc cag gga cat gga cag gtg ccc gat cag atc ctt      624
 Arg Val Ser Gln Thr Gln Gly His Gly Gln Val Pro Asp Gln Ile Leu
         195                 200                 205

 cag gct ctg ctc agc gca gct tgg cag aca gcg tcc agc cac aca gat      672
 Gln Ala Leu Leu Ser Ala Ala Trp Gln Thr Ala Ser Ser His Thr Asp
     210                 215                 220

 gtc agg ggc tcc agg ctg aca cag ggt ccc atc ctg gac ctt ttc agt      720
 Val Arg Gly Ser Arg Leu Thr Gln Gly Pro Ile Leu Asp Leu Phe Ser
 225                 230                 235                 240

 gtg acg gac ata gaa gcg gaa gcc acg ggg ccg gca gtt cag ttc aca      768
 Val Thr Asp Ile Glu Ala Glu Ala Thr Gly Pro Ala Val Gln Phe Thr
                 245                 250                 255

 gcg ctg gga gcc ctg gac taa                                          789
 Ala Leu Gly Ala Leu Asp 
             260





      <210> 929
      <211> 1317
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1317)

      <400> 929
  atg aaa agg aga gac tgg cct agc ctc cca gcc tac atc ttt ctc cca      48
  Met Lys Arg Arg Asp Trp Pro Ser Leu Pro Ala Tyr Ile Phe Leu Pro
    1               5                  10                  15

 tgc tgg atg ctt cct gcc ctc gaa cat cag act cca agt tct tca gtt       96
 Cys Trp Met Leu Pro Ala Leu Glu His Gln Thr Pro Ser Ser Ser Val
              20                  25                  30

 ttg aga ctc aga ctg gct ctc ctt gct cct caa act tgc aga cag act      144
 Leu Arg Leu Arg Leu Ala Leu Leu Ala Pro Gln Thr Cys Arg Gln Thr
          35                  40                  45

 att gtg gga cct tgt gat tgt ata tcc aca ctg atc cgt tac att gat      192
 Ile Val Gly Pro Cys Asp Cys Ile Ser Thr Leu Ile Arg Tyr Ile Asp
      50                  55                  60

 gac agc atg ctg att gga tcc agt gag caa gaa gta gct aac aca ctg      240
 Asp Ser Met Leu Ile Gly Ser Ser Glu Gln Glu Val Ala Asn Thr Leu
  65                  70                  75                  80

 gac tta ttt gtg aga cat ttg cat gcc aga gaa tgg gaa ata aaa ctg      288
 Asp Leu Phe Val Arg His Leu His Ala Arg Glu Trp Glu Ile Lys Leu
                  85                  90                  95

 act aaa att cag gga cct tct acc tca gta aaa ttt cta ggg gtc cag      336
 Thr Lys Ile Gln Gly Pro Ser Thr Ser Val Lys Phe Leu Gly Val Gln
             100                 105                 110

 tgg tat ggg gcc tgt caa gat att cct tct aat gta aag gat acg ttg      384
 Trp Tyr Gly Ala Cys Gln Asp Ile Pro Ser Asn Val Lys Asp Thr Leu
         115                 120                 125

 ctg cat ttg gcc cct ccc ata acc aag aaa gag gca caa tgc cta ctg      432
 Leu His Leu Ala Pro Pro Ile Thr Lys Lys Glu Ala Gln Cys Leu Leu
     130                 135                 140

 ggc cta ttt gga ttt tgg agg caa cac att cct cat ttg gaa ttg cct      480
 Gly Leu Phe Gly Phe Trp Arg Gln His Ile Pro His Leu Glu Leu Pro
 145                 150                 155                 160

 atc aag aac tgg gtg ctt tct gac cca tct agc tat aaa gtg ggt tgt      528
 Ile Lys Asn Trp Val Leu Ser Asp Pro Ser Ser Tyr Lys Val Gly Cys
                 165                 170                 175

 gca cag cag tat tcc atc atc aaa tgg aag tgg tat ata tgt gat tgg      576
 Ala Gln Gln Tyr Ser Ile Ile Lys Trp Lys Trp Tyr Ile Cys Asp Trp
             180                 185                 190

 gct caa gca aat cca gaa ggc aca atc aat ggt ttg gct cga tgg tca      624
 Ala Gln Ala Asn Pro Glu Gly Thr Ile Asn Gly Leu Ala Arg Trp Ser
         195                 200                 205

 ggg act tgg aag aag cac aat tgg aaa att ggt gac aaa gaa att tgg      672
 Gly Thr Trp Lys Lys His Asn Trp Lys Ile Gly Asp Lys Glu Ile Trp
     210                 215                 220

 gga aga ggc atg tgg atg gac ctc tct gag tgg tca aaa act gtg aag      720
 Gly Arg Gly Met Trp Met Asp Leu Ser Glu Trp Ser Lys Thr Val Lys
 225                 230                 235                 240

 ata tat gta tcc cat gta agt gct cac caa cag atg acc tca gca gag      768
 Ile Tyr Val Ser His Val Ser Ala His Gln Gln Met Thr Ser Ala Glu
                 245                 250                 255

 gag gat ttt aat aat caa gtg gat agg atg acc cgt tct atg gac acc      816
 Glu Asp Phe Asn Asn Gln Val Asp Arg Met Thr Arg Ser Met Asp Thr
             260                 265                 270

 aca cag cct ctt tcc cca acc act cct gtc atc acc caa tgg gcc cat      864
 Thr Gln Pro Leu Ser Pro Thr Thr Pro Val Ile Thr Gln Trp Ala His
         275                 280                 285

 gaa caa agt gac cat ggt ggc agg gat gga gat tat aca tgg gct cag      912
 Glu Gln Ser Asp His Gly Gly Arg Asp Gly Asp Tyr Thr Trp Ala Gln
     290                 295                 300

 caa cat gga ctt cca ctc acc aag tca ttc act ttt gct aaa gaa gtg      960
 Gln His Gly Leu Pro Leu Thr Lys Ser Phe Thr Phe Ala Lys Glu Val
 305                 310                 315                 320

 tgg cag tgg gct cat gct cat gga att cac tgg tct tat gtt ccc cat     1008
 Trp Gln Trp Ala His Ala His Gly Ile His Trp Ser Tyr Val Pro His
                 325                 330                 335

 cat cct gaa gca gct gga ttg ata gaa cga tgg aat ggc ctt ttg aag     1056
 His Pro Glu Ala Ala Gly Leu Ile Glu Arg Trp Asn Gly Leu Leu Lys
             340                 345                 350

 tca caa tta aaa tgc caa cta ggt gac aat act ttg cag ggc tgg ggc     1104
 Ser Gln Leu Lys Cys Gln Leu Gly Asp Asn Thr Leu Gln Gly Trp Gly
         355                 360                 365

 aaa gtt ctc cag aag gct ata atc aaa gct gaa aag ctg caa atg gtt     1152
 Lys Val Leu Gln Lys Ala Ile Ile Lys Ala Glu Lys Leu Gln Met Val
     370                 375                 380

 ctt caa atg gag ccc cag atg caa tcc atg act aaa atc tac cat ggc     1200
 Leu Gln Met Glu Pro Gln Met Gln Ser Met Thr Lys Ile Tyr His Gly
 385                 390                 395                 400

 ccc ctg gac cgg cat gct agc cca tgc tct gat gtt aat gac atc aaa     1248
 Pro Leu Asp Arg His Ala Ser Pro Cys Ser Asp Val Asn Asp Ile Lys
                 405                 410                 415

 gcc acc cct ccc aag gaa atc tca act gca cga ccc cta cta cgc ccc     1296
 Ala Thr Pro Pro Lys Glu Ile Ser Thr Ala Arg Pro Leu Leu Arg Pro
             420                 425                 430

 aat tca gca gga agc agt tag                                         1317
 Asn Ser Ala Gly Ser Ser 
         435





      <210> 930
      <211> 192
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(192)

      <400> 930
  atg cta att caa ggt agt gcc tgg tgg tgt gga aca atc att ttg aaa      48
  Met Leu Ile Gln Gly Ser Ala Trp Trp Cys Gly Thr Ile Ile Leu Lys
    1               5                  10                  15

 ttt ctg aca tct aaa atc tta ggc gtt tca gac cac att cgc ctg agt       96
 Phe Leu Thr Ser Lys Ile Leu Gly Val Ser Asp His Ile Arg Leu Ser
              20                  25                  30

 gat ctt ata gca gcc aga atc tta agg tat aca gat ttt gat act tta      144
 Asp Leu Ile Ala Ala Arg Ile Leu Arg Tyr Thr Asp Phe Asp Thr Leu
          35                  40                  45

 ata tat acc tgt gct ccc gaa ttt gac ttc atg gaa aaa gcg gta tga      192
 Ile Tyr Thr Cys Ala Pro Glu Phe Asp Phe Met Glu Lys Ala Val 
      50                  55                  60





      <210> 931
      <211> 627
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(627)

      <400> 931
  atg aga aag gca tcc tgg cca ctt cac ttg aca agc act gca gct gca      48
  Met Arg Lys Ala Ser Trp Pro Leu His Leu Thr Ser Thr Ala Ala Ala
    1               5                  10                  15

 tgg gtg att aag gct gct ggt gct gat aca acc gaa aat cgc agg aag       96
 Trp Val Ile Lys Ala Ala Gly Ala Asp Thr Thr Glu Asn Arg Arg Lys
              20                  25                  30

 aac aga aca gtc cca cac gtg cga gtg ctg cac tct ccc cag aca ctg      144
 Asn Arg Thr Val Pro His Val Arg Val Leu His Ser Pro Gln Thr Leu
          35                  40                  45

 agt ttt gag cct ggc gta gtt cac tgg tcc atg gga gcg cag gat cta      192
 Ser Phe Glu Pro Gly Val Val His Trp Ser Met Gly Ala Gln Asp Leu
      50                  55                  60

 acc acc atc tct atg ctg gtg ggt ttg ccc agg ctc tgt gtg tgg tgg      240
 Thr Thr Ile Ser Met Leu Val Gly Leu Pro Arg Leu Cys Val Trp Trp
  65                  70                  75                  80

 tcc ctg tca tgc agg aag cag tgg gtg ctg tgg aac agg ctg tgt ggg      288
 Ser Leu Ser Cys Arg Lys Gln Trp Val Leu Trp Asn Arg Leu Cys Gly
                  85                  90                  95

 gct ggt cgc tgc tgt tcc agg acc act gca gcc gat tgc ctg gga aag      336
 Ala Gly Arg Cys Cys Ser Arg Thr Thr Ala Ala Asp Cys Leu Gly Lys
             100                 105                 110

 gca tca ggg agc aag agt tgt tcc atg atg gac gta act ctt ttg gat      384
 Ala Ser Gly Ser Lys Ser Cys Ser Met Met Asp Val Thr Leu Leu Asp
         115                 120                 125

 gaa cat ggg aaa ccc ttt tgg tgt ttc agt tcc ccg gtg tgc ctg aga      432
 Glu His Gly Lys Pro Phe Trp Cys Phe Ser Ser Pro Val Cys Leu Arg
     130                 135                 140

 tcg cct gcc aca ccc tct gac agc tct agc ttc ttg gga cag aca tac      480
 Ser Pro Ala Thr Pro Ser Asp Ser Ser Ser Phe Leu Gly Gln Thr Tyr
 145                 150                 155                 160

 aac gtg gac tac gtt gat gcg gaa gga aga gtg cac gtg gag ctg cac      528
 Asn Val Asp Tyr Val Asp Ala Glu Gly Arg Val His Val Glu Leu His
                 165                 170                 175

 cta gga gca tgc cag gtg ctc cat aat cga tac tca ata acg att tgt      576
 Leu Gly Ala Cys Gln Val Leu His Asn Arg Tyr Ser Ile Thr Ile Cys
             180                 185                 190

 caa acc aat gga aac cgt tat cgg gat ata cca gca gct atg gga gca      624
 Gln Thr Asn Gly Asn Arg Tyr Arg Asp Ile Pro Ala Ala Met Gly Ala
         195                 200                 205

 tga                                                                  627
 






      <210> 932
      <211> 702
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(702)

      <400> 932
  atg cgc ttc gtc atg tct gtg acg atg tat cac acg acg ttg gtg ggg      48
  Met Arg Phe Val Met Ser Val Thr Met Tyr His Thr Thr Leu Val Gly
    1               5                  10                  15

 ttg gat att aaa cac ctc aac ctg gag tct ggt aaa gtg tgg gtt atg       96
 Leu Asp Ile Lys His Leu Asn Leu Glu Ser Gly Lys Val Trp Val Met
              20                  25                  30

 gga aaa gcc agc aaa gag ccc cgc ctc ccg att ggt cgc aac gct gtg      144
 Gly Lys Ala Ser Lys Glu Pro Arg Leu Pro Ile Gly Arg Asn Ala Val
          35                  40                  45

 gcg tgg att gag cac tgg ctt gat ttg cgc gac ctg ttt ggt agc aaa      192
 Ala Trp Ile Glu His Trp Leu Asp Leu Arg Asp Leu Phe Gly Ser Lys
      50                  55                  60

 gac gac gcg ctt ttt ctg tcg aaa ctg ggc aag cgt atc tcc gcg cgt      240
 Asp Asp Ala Leu Phe Leu Ser Lys Leu Gly Lys Arg Ile Ser Ala Arg
  65                  70                  75                  80

 aat gtg cag aaa cgc ttt gcc gaa tgg ggc ata aaa caa ggg ctg aat      288
 Asn Val Gln Lys Arg Phe Ala Glu Trp Gly Ile Lys Gln Gly Leu Asn
                  85                  90                  95

 aat cac gtt cat ccg cat aaa tta cgt cac tcg ttc gcc acg cat atg      336
 Asn His Val His Pro His Lys Leu Arg His Ser Phe Ala Thr His Met
             100                 105                 110

 ctg gag tcg agc ggc gat ctt cgt ggt ctt ttc cgc ttt gta agc gca      384
 Leu Glu Ser Ser Gly Asp Leu Arg Gly Leu Phe Arg Phe Val Ser Ala
         115                 120                 125

 aaa cgg cac gcg aaa ggt tcc aaa gtt ggg tcg ccc ata att tac gcg      432
 Lys Arg His Ala Lys Gly Ser Lys Val Gly Ser Pro Ile Ile Tyr Ala
     130                 135                 140

 gac cag atc atc att ggt gcc ggt cag aac cat ccg gcc cgg tgg cgg      480
 Asp Gln Ile Ile Ile Gly Ala Gly Gln Asn His Pro Ala Arg Trp Arg
 145                 150                 155                 160

 ggc tta ccc cgg aaa tca cgc tta ttg gtc agt cct tca aac gac aaa      528
 Gly Leu Pro Arg Lys Ser Arg Leu Leu Val Ser Pro Ser Asn Asp Lys
                 165                 170                 175

 cgc aga aaa gca ggc gcc gca ccc gtt gcc gca ctg cgc cat ttc cct      576
 Arg Arg Lys Ala Gly Ala Ala Pro Val Ala Ala Leu Arg His Phe Pro
             180                 185                 190

 ccc atc agc att gaa aat gcg ata gtg aaa atc cag ttc agg atc att      624
 Pro Ile Ser Ile Glu Asn Ala Ile Val Lys Ile Gln Phe Arg Ile Ile
         195                 200                 205

 cgg cgg ctc aac cac cag cag ttg gtc aaa ccc tac ccc cag gtg ccg      672
 Arg Arg Leu Asn His Gln Gln Leu Val Lys Pro Tyr Pro Gln Val Pro
     210                 215                 220

 atc agc cag gcg acg aat cag ttc cgg tga                              702
 Ile Ser Gln Ala Thr Asn Gln Phe Arg 
 225                 230





      <210> 933
      <211> 996
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(996)

      <400> 933
  atg gtt ttc gcc agt ata ttg cta ctg atg gcg ctc gtg gta ctg cct      48
  Met Val Phe Ala Ser Ile Leu Leu Leu Met Ala Leu Val Val Leu Pro
    1               5                  10                  15

 atc gcc tgg caa cag ggc atc tac tta atc cgc gat atg ccg ggg atg       96
 Ile Ala Trp Gln Gln Gly Ile Tyr Leu Ile Arg Asp Met Pro Gly Met
              20                  25                  30

 ctc aat aac ctt tct gac ttt gcc gtc acg ttg ccg tgc cgc tat ccg      144
 Leu Asn Asn Leu Ser Asp Phe Ala Val Thr Leu Pro Cys Arg Tyr Pro
          35                  40                  45

 tcg tta atg gac gca ggc att att gat gca atg gcc gca aat atg cgc      192
 Ser Leu Met Asp Ala Gly Ile Ile Asp Ala Met Ala Ala Asn Met Arg
      50                  55                  60

 agc ccg atg ctg tcc atg tgc gac ttc ggg gtg aaa att tcc ctc tgc      240
 Ser Pro Met Leu Ser Met Cys Asp Phe Gly Val Lys Ile Ser Leu Cys
  65                  70                  75                  80

 tcg atg gcc ggc ttg ctg acc ata gcc tgt tat ctg gtg ctg gtg cca      288
 Ser Met Ala Gly Leu Leu Thr Ile Ala Cys Tyr Leu Val Leu Val Pro
                  85                  90                  95

 ttg atg gac atc tta ctg ctg aac gac aaa gaa gag atg ctg aaa ccc      336
 Leu Met Asp Ile Leu Leu Leu Asn Asp Lys Glu Glu Met Leu Lys Pro
             100                 105                 110

 cat cgc ccg ggg ctg act cgt tac cag ggg ctg gca cga caa ctc ggt      384
 His Arg Pro Gly Leu Thr Arg Tyr Gln Gly Leu Ala Arg Gln Leu Gly
         115                 120                 125

 acc ctc gat gaa att gac gaa ctg acg tta gaa ctt cag cct aaa ctg      432
 Thr Leu Asp Glu Ile Asp Glu Leu Thr Leu Glu Leu Gln Pro Lys Leu
     130                 135                 140

 ctg cgc gta ttg caa gag cgt gag att gag cgt atc ggc ggg agt aga      480
 Leu Arg Val Leu Gln Glu Arg Glu Ile Glu Arg Ile Gly Gly Ser Arg
 145                 150                 155                 160

 acg atc ccg gcg aat gtc aga gtc att gcc gcc acc aac cgc gat ttg      528
 Thr Ile Pro Ala Asn Val Arg Val Ile Ala Ala Thr Asn Arg Asp Leu
                 165                 170                 175

 tgg caa atg ggt gaa gat cgc cag ttt cgc agc gat ctc ttt tat cgc      576
 Trp Gln Met Gly Glu Asp Arg Gln Phe Arg Ser Asp Leu Phe Tyr Arg
             180                 185                 190

 ctg aat gtg ttc cca ctg gaa ttg ccg ccg cta cgc gac cgt gcg gaa      624
 Leu Asn Val Phe Pro Leu Glu Leu Pro Pro Leu Arg Asp Arg Ala Glu
         195                 200                 205

 gat ata cct ctt tta gca aaa cat ttc acg cat aaa atg gcg cgt cat      672
 Asp Ile Pro Leu Leu Ala Lys His Phe Thr His Lys Met Ala Arg His
     210                 215                 220

 atg aat cgc gca aga gac gcc atc ccg acc gag gca cta cgc cag ttg      720
 Met Asn Arg Ala Arg Asp Ala Ile Pro Thr Glu Ala Leu Arg Gln Leu
 225                 230                 235                 240

 atg tcc ggg gat tgg ccg cgc aac gtg cgc gag ctg gaa aac gtg att      768
 Met Ser Gly Asp Trp Pro Arg Asn Val Arg Glu Leu Glu Asn Val Ile
                 245                 250                 255

 gag cgg acg cta ctg gtg act cgt gga aac agt ctg aat tta cat cta      816
 Glu Arg Thr Leu Leu Val Thr Arg Gly Asn Ser Leu Asn Leu His Leu
             260                 265                 270

 aat gtt cga caa agg cgt tta ctg ccg acg cta aat gaa gat tca gcg      864
 Asn Val Arg Gln Arg Arg Leu Leu Pro Thr Leu Asn Glu Asp Ser Ala
         275                 280                 285

 ctt cgc agg tca atg gcg cag gta ctg cac ccg act acg tcc gag aat      912
 Leu Arg Arg Ser Met Ala Gln Val Leu His Pro Thr Thr Ser Glu Asn
     290                 295                 300

 gac gaa gaa gaa cgt ttg tgc att ggt caa gca ttg cga gaa acc aat      960
 Asp Glu Glu Glu Arg Leu Cys Ile Gly Gln Ala Leu Arg Glu Thr Asn
 305                 310                 315                 320

 ggc att gtt gcc cgg ccc cgt ggc gca ctg acg tga                      996
 Gly Ile Val Ala Arg Pro Arg Gly Ala Leu Thr 
                 325                 330





      <210> 934
      <211> 801
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(801)

      <400> 934
  atg ggg agg aga agg gcg cgg tgg tgg ctg gag gcg cca tgc atg tgg      48
  Met Gly Arg Arg Arg Ala Arg Trp Trp Leu Glu Ala Pro Cys Met Trp
    1               5                  10                  15

 agc ctg gtc ccc ctc cat gca gct tct cgg agt cag agg atc ccc ccg       96
 Ser Leu Val Pro Leu His Ala Ala Ser Arg Ser Gln Arg Ile Pro Pro
              20                  25                  30

 gaa ctg gat acc cag cta cgg cct aaa cat ctg gat gtc agc gcg ctg      144
 Glu Leu Asp Thr Gln Leu Arg Pro Lys His Leu Asp Val Ser Ala Leu
          35                  40                  45

 gat acg ccc acg ctt gct ctg gcg aac gcc gcg cgc gaa acc ctg cgc      192
 Asp Thr Pro Thr Leu Ala Leu Ala Asn Ala Ala Arg Glu Thr Leu Arg
      50                  55                  60

 att ggc gac gcc atg gaa cag atg atg gaa ggg ttg aat aaa gtg atg      240
 Ile Gly Asp Ala Met Glu Gln Met Met Glu Gly Leu Asn Lys Val Met
  65                  70                  75                  80

 cac ggt gag cca cgg cag gag aaa gag ctg cgt aag ctg gca gat gat      288
 His Gly Glu Pro Arg Gln Glu Lys Glu Leu Arg Lys Leu Ala Asp Asp
                  85                  90                  95

 atc aac gtt ctc tac acc gcc att aag ctg tat ctg gcg cgg atg cca      336
 Ile Asn Val Leu Tyr Thr Ala Ile Lys Leu Tyr Leu Ala Arg Met Pro
             100                 105                 110

 aaa gaa gag ctg gcg gag gaa gag tcg cgc cgc tgg gca gag atc atc      384
 Lys Glu Glu Leu Ala Glu Glu Glu Ser Arg Arg Trp Ala Glu Ile Ile
         115                 120                 125

 gaa atg tcg ctc aac ctt gaa cag gcc tcc gat atc gtc gag cgc atg      432
 Glu Met Ser Leu Asn Leu Glu Gln Ala Ser Asp Ile Val Glu Arg Met
     130                 135                 140

 ggc agc gaa att gct gac aaa tca ctg gca gca cgg cgg gca ttt tcg      480
 Gly Ser Glu Ile Ala Asp Lys Ser Leu Ala Ala Arg Arg Ala Phe Ser
 145                 150                 155                 160

 ctt gat ggg ttg aag gaa ctg gat gcg ctc tat gag caa ttg ctc agt      528
 Leu Asp Gly Leu Lys Glu Leu Asp Ala Leu Tyr Glu Gln Leu Leu Ser
                 165                 170                 175

 aat tta aag ctg gca atg tcg gtg ttc ttc tct ggc gat gtc acc agc      576
 Asn Leu Lys Leu Ala Met Ser Val Phe Phe Ser Gly Asp Val Thr Ser
             180                 185                 190

 gct cgt cgt ttg cgt cgc agc aaa cat cgt ttt cgc att ctt aat cgc      624
 Ala Arg Arg Leu Arg Arg Ser Lys His Arg Phe Arg Ile Leu Asn Arg
         195                 200                 205

 cgc tat tcc cac gcc cac gtc gat cgc ctg cat cag caa aac gtg cag      672
 Arg Tyr Ser His Ala His Val Asp Arg Leu His Gln Gln Asn Val Gln
     210                 215                 220

 agc att gaa acc agt tcg cta cat tta ggc tta ctg gga gat atg cag      720
 Ser Ile Glu Thr Ser Ser Leu His Leu Gly Leu Leu Gly Asp Met Gln
 225                 230                 235                 240

 cgc ctg aac tcg ctg ttt tgt tcg gtg gct tac agt gtg ctg gaa cag      768
 Arg Leu Asn Ser Leu Phe Cys Ser Val Ala Tyr Ser Val Leu Glu Gln
                 245                 250                 255

 ccg gat gaa gat gaa gga cgg gac gag tat taa                          801
 Pro Asp Glu Asp Glu Gly Arg Asp Glu Tyr 
             260                 265





      <210> 935
      <211> 1434
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1434)

      <400> 935
  atg ccc ggc ttg ctg aat tgg atc acg ggg gca gcc ctg ccc ctc acc      48
  Met Pro Gly Leu Leu Asn Trp Ile Thr Gly Ala Ala Leu Pro Leu Thr
    1               5                  10                  15

 gcg tct gat gtt acc tcc tgt gtc agc ggt tat gcc ctg ggc cta act       96
 Ala Ser Asp Val Thr Ser Cys Val Ser Gly Tyr Ala Leu Gly Leu Thr
              20                  25                  30

 gcc tcc ctc acc tat ggc aac ctg gaa gcc cag ccc ttc cag ggc ctc      144
 Ala Ser Leu Thr Tyr Gly Asn Leu Glu Ala Gln Pro Phe Gln Gly Leu
          35                  40                  45

 ttc gtg tac ccc ctg gat gag tgc acc acg gtg atc ggc ttt gag gca      192
 Phe Val Tyr Pro Leu Asp Glu Cys Thr Thr Val Ile Gly Phe Glu Ala
      50                  55                  60

 gtc att gcc gac cgt gtc gtg aca gta cag atc aag gac aaa gcc aag      240
 Val Ile Ala Asp Arg Val Val Thr Val Gln Ile Lys Asp Lys Ala Lys
  65                  70                  75                  80

 ctg gag agc ggc cac ttc gat gcc tcc cat gtt cga tcc cca aca gtc      288
 Leu Glu Ser Gly His Phe Asp Ala Ser His Val Arg Ser Pro Thr Val
                  85                  90                  95

 aca ggg aac att ctg caa gac ggg gtt tcc ata gcc cct cat tcc tgc      336
 Thr Gly Asn Ile Leu Gln Asp Gly Val Ser Ile Ala Pro His Ser Cys
             100                 105                 110

 aca ccg gga aag gtg acc ttg gac gag gat ttg gag cgg atc ctg ttc      384
 Thr Pro Gly Lys Val Thr Leu Asp Glu Asp Leu Glu Arg Ile Leu Phe
         115                 120                 125

 gtg gcc aac ctg ggg acc att gcc ccc atg gag aat gtc acc atc ttc      432
 Val Ala Asn Leu Gly Thr Ile Ala Pro Met Glu Asn Val Thr Ile Phe
     130                 135                 140

 atc agc acc tcc tcg gag ctc cca acg ctg ccc agc ggg gct gtg agg      480
 Ile Ser Thr Ser Ser Glu Leu Pro Thr Leu Pro Ser Gly Ala Val Arg
 145                 150                 155                 160

 gtc ctt ctg cct gct gtc tgt gcc cca acc gtg ccc cag ttc tgc acc      528
 Val Leu Leu Pro Ala Val Cys Ala Pro Thr Val Pro Gln Phe Cys Thr
                 165                 170                 175

 aag agc act ggc acc tcc aac caa cag gcc cag ggc aaa gac agg cac      576
 Lys Ser Thr Gly Thr Ser Asn Gln Gln Ala Gln Gly Lys Asp Arg His
             180                 185                 190

 tgc ttc ggt gcc tgg gcc ccg ggc tcc tgg aat aag ttg tgc ctg gcg      624
 Cys Phe Gly Ala Trp Ala Pro Gly Ser Trp Asn Lys Leu Cys Leu Ala
         195                 200                 205

 act ctc ctg aac acc gaa gtg tcc aac ccc atg gag tat gag ttc aac      672
 Thr Leu Leu Asn Thr Glu Val Ser Asn Pro Met Glu Tyr Glu Phe Asn
     210                 215                 220

 ttc cag ctg gag atc cgt ggg cca tgt ctg ctc gca ggg gtg gag agt      720
 Phe Gln Leu Glu Ile Arg Gly Pro Cys Leu Leu Ala Gly Val Glu Ser
 225                 230                 235                 240

 ccc act cat gag att cgt gcc gac gcc gcc cca tct gcc cgc tcg gcc      768
 Pro Thr His Glu Ile Arg Ala Asp Ala Ala Pro Ser Ala Arg Ser Ala
                 245                 250                 255

 aag agc atc atc atc acc ttg gcc aac aag cac acc ttt gac cgg cct      816
 Lys Ser Ile Ile Ile Thr Leu Ala Asn Lys His Thr Phe Asp Arg Pro
             260                 265                 270

 gtg gag atc ctc atc cac ccc agc ggt acg gtg ccc cac aac ggg ccc      864
 Val Glu Ile Leu Ile His Pro Ser Gly Thr Val Pro His Asn Gly Pro
         275                 280                 285

 ctg ggc tgc ctg tgg gag gga gga gag ccc cat atg ccc cat gtc ctg      912
 Leu Gly Cys Leu Trp Glu Gly Gly Glu Pro His Met Pro His Val Leu
     290                 295                 300

 ata gag aaa ggg gac atg acc ctg gga gag ttt gac cag cac ttg aag      960
 Ile Glu Lys Gly Asp Met Thr Leu Gly Glu Phe Asp Gln His Leu Lys
 305                 310                 315                 320

 gga aga aca gat ttc att aaa ggg atg aag aag aag agc aga gca gag     1008
 Gly Arg Thr Asp Phe Ile Lys Gly Met Lys Lys Lys Ser Arg Ala Glu
                 325                 330                 335

 cgg aag ggc tct gtc atc aaa aga gcc cgt ctg ggc tgt ggc ctc tgg     1056
 Arg Lys Gly Ser Val Ile Lys Arg Ala Arg Leu Gly Cys Gly Leu Trp
             340                 345                 350

 tgg agc ggc ttc acg tgg gag aga gac agc gag atc cct tgg cag gga     1104
 Trp Ser Gly Phe Thr Trp Glu Arg Asp Ser Glu Ile Pro Trp Gln Gly
         355                 360                 365

 gaa gag tgg gtt gtg ggt atc cac agg gtg aac atc aat cag gaa gag     1152
 Glu Glu Trp Val Val Gly Ile His Arg Val Asn Ile Asn Gln Glu Glu
     370                 375                 380

 tgg aca gaa atc att cga aaa cgc ctc cac aaa gac att ccc cac cac     1200
 Trp Thr Glu Ile Ile Arg Lys Arg Leu His Lys Asp Ile Pro His His
 385                 390                 395                 400

 tcc gtc atc atg ctc aac ttc tgt ccc gac ctc cag tca gtc cag ccg     1248
 Ser Val Ile Met Leu Asn Phe Cys Pro Asp Leu Gln Ser Val Gln Pro
                 405                 410                 415

 tgc ctg aga aag gcc cac ggg gag ttc atc ttc ctc att gac agg agc     1296
 Cys Leu Arg Lys Ala His Gly Glu Phe Ile Phe Leu Ile Asp Arg Ser
             420                 425                 430

 agc agc atg agc ggg atc agc atg cac cga gtc aag gtg cca agc ctt     1344
 Ser Ser Met Ser Gly Ile Ser Met His Arg Val Lys Val Pro Ser Leu
         435                 440                 445

 gcc ctt ggc cat ctg gaa aaa cag cag aat gta aac aca ttt gct gtc     1392
 Ala Leu Gly His Leu Glu Lys Gln Gln Asn Val Asn Thr Phe Ala Val
     450                 455                 460

 ctc aag gag ctg aca gtc aag aga gag gca cag gcc tgc tag             1434
 Leu Lys Glu Leu Thr Val Lys Arg Glu Ala Gln Ala Cys 
 465                 470                 475





      <210> 936
      <211> 564
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(564)

      <400> 936
  atg ggc ctc ctg ctg ttt ccc aag cct gcc tgc ttc cgg gtc tct gca      48
  Met Gly Leu Leu Leu Phe Pro Lys Pro Ala Cys Phe Arg Val Ser Ala
    1               5                  10                  15

 ctg gct gtt ccc tct ggc tgc atg cca tgc ggt gag aac gtg atg ttg       96
 Leu Ala Val Pro Ser Gly Cys Met Pro Cys Gly Glu Asn Val Met Leu
              20                  25                  30

 gag caa cgg cag cca tct gag acc atg agg aga ggc act gct gac acg      144
 Glu Gln Arg Gln Pro Ser Glu Thr Met Arg Arg Gly Thr Ala Asp Thr
          35                  40                  45

 cac agg gtg cag tgt ggg aga ggg aac att tgg gca tcc atc atg acc      192
 His Arg Val Gln Cys Gly Arg Gly Asn Ile Trp Ala Ser Ile Met Thr
      50                  55                  60

 ctg cag aca gcg aat gtg tcc atg cta aag ctt gcg cct tcc tgg tct      240
 Leu Gln Thr Ala Asn Val Ser Met Leu Lys Leu Ala Pro Ser Trp Ser
  65                  70                  75                  80

 tta gaa cat tca aga gcc tgg cgc aca gca ggg cct cct aga gcc ttt      288
 Leu Glu His Ser Arg Ala Trp Arg Thr Ala Gly Pro Pro Arg Ala Phe
                  85                  90                  95

 gtg gag cgg atg aat gca gcc cgc agc cat tgg atg ggg gcc gtg caa      336
 Val Glu Arg Met Asn Ala Ala Arg Ser His Trp Met Gly Ala Val Gln
             100                 105                 110

 cgc ctg atg aaa atc atc atg ctc aat tat cgg ctt gtg gca cat ttc      384
 Arg Leu Met Lys Ile Ile Met Leu Asn Tyr Arg Leu Val Ala His Phe
         115                 120                 125

 cta gtt ttg ttt gcc cag aaa aaa gca aac cgt cag cgc act agg gtt      432
 Leu Val Leu Phe Ala Gln Lys Lys Ala Asn Arg Gln Arg Thr Arg Val
     130                 135                 140

 cat cga ggg tcg tta tgg tta agc gag tgt gaa tct cca aat ggc cca      480
 His Arg Gly Ser Leu Trp Leu Ser Glu Cys Glu Ser Pro Asn Gly Pro
 145                 150                 155                 160

 ggg ggc cgt cat acc gaa ccc gca gaa ggc agg cag gca cgg ggc cgc      528
 Gly Gly Arg His Thr Glu Pro Ala Glu Gly Arg Gln Ala Arg Gly Arg
                 165                 170                 175

 aca ccg cag cag gga ttt gca gtg tcc tta atg tga                      564
 Thr Pro Gln Gln Gly Phe Ala Val Ser Leu Met 
             180                 185





      <210> 937
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 937
  atg aac aaa cac ttc ttg ttc ctc ttc ctc ctt tac tgc ctc att gtg      48
  Met Asn Lys His Phe Leu Phe Leu Phe Leu Leu Tyr Cys Leu Ile Val
    1               5                  10                  15

 gca gtg aca tca ctt cag tgc ata aca tgc cac ctt cgc aca cgg aca       96
 Ala Val Thr Ser Leu Gln Cys Ile Thr Cys His Leu Arg Thr Arg Thr
              20                  25                  30

 gac cgc tgt aga aga ggc ttt ggt gtc tgt act gct cag aag ggc gag      144
 Asp Arg Cys Arg Arg Gly Phe Gly Val Cys Thr Ala Gln Lys Gly Glu
          35                  40                  45

 gca tgc atg ctc tta agg att tac cag cgc aat act ctc cag ata tca      192
 Ala Cys Met Leu Leu Arg Ile Tyr Gln Arg Asn Thr Leu Gln Ile Ser
      50                  55                  60

 tac atg gtg tgt cag aaa ttc tgc aga gac atg aca ttt gat ctc agg      240
 Tyr Met Val Cys Gln Lys Phe Cys Arg Asp Met Thr Phe Asp Leu Arg
  65                  70                  75                  80

 aat cgg act tat gtt cat aca tgc tgc aac tac aat tac tgt aac ttt      288
 Asn Arg Thr Tyr Val His Thr Cys Cys Asn Tyr Asn Tyr Cys Asn Phe
                  85                  90                  95

 aaa ctc taa                                                          297
 Lys Leu 






      <210> 938
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 938
  atg aca gcg gga acg gtt gtg atc act ggc gga atc cta gct acg gtg      48
  Met Thr Ala Gly Thr Val Val Ile Thr Gly Gly Ile Leu Ala Thr Val
    1               5                  10                  15

 atc ctc ctc tgc atc att gcc gtc ctg tgc tac tgc agg ctc cag tat       96
 Ile Leu Leu Cys Ile Ile Ala Val Leu Cys Tyr Cys Arg Leu Gln Tyr
              20                  25                  30

 tac tgc tgc aag aag agc gga acc gag gtt gca gac gag gag gag gag      144
 Tyr Cys Cys Lys Lys Ser Gly Thr Glu Val Ala Asp Glu Glu Glu Glu
          35                  40                  45

 cgg gag cac gac ctt ccc acg cat ccc aga ggc ccc acc tgc aat gcc      192
 Arg Glu His Asp Leu Pro Thr His Pro Arg Gly Pro Thr Cys Asn Ala
      50                  55                  60

 tgc agc tcc caa gcc ctg gac ggc aga ggc agc ctg gcg cct ctc acc      240
 Cys Ser Ser Gln Ala Leu Asp Gly Arg Gly Ser Leu Ala Pro Leu Thr
  65                  70                  75                  80

 agc gag ccc tgc agc cag ccc tgt ggc caa tca acc aca gca gcc gtg      288
 Ser Glu Pro Cys Ser Gln Pro Cys Gly Gln Ser Thr Thr Ala Ala Val
                  85                  90                  95

 tcc tcc ttg cca gaa ata aca tca ttc gta cgt cct gcc ttt gta aaa      336
 Ser Ser Leu Pro Glu Ile Thr Ser Phe Val Arg Pro Ala Phe Val Lys
             100                 105                 110

 atc aag acc cag tta acc atc acc cac ttc ttg ccc ctg att gat ggg      384
 Ile Lys Thr Gln Leu Thr Ile Thr His Phe Leu Pro Leu Ile Asp Gly
         115                 120                 125

 gtc cct gag tac aag cgt cct gtg caa tcc cct ccc tcc tac cgc ttt      432
 Val Pro Glu Tyr Lys Arg Pro Val Gln Ser Pro Pro Ser Tyr Arg Phe
     130                 135                 140

 cct agc taa                                                          441
 Pro Ser 
 145





      <210> 939
      <211> 348
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(348)

      <400> 939
  atg ctc cac acc agg aga gtg tgc atc ttc acg ctc ctt cct tgc ctg      48
  Met Leu His Thr Arg Arg Val Cys Ile Phe Thr Leu Leu Pro Cys Leu
    1               5                  10                  15

 aca aaa cct gct ctc ttg gcc atg gag acc act ctg aca tca ctt ctg       96
 Thr Lys Pro Ala Leu Leu Ala Met Glu Thr Thr Leu Thr Ser Leu Leu
              20                  25                  30

 ctt ggt gag cag ggg cgg tca gat gcc ctg gcc ttg gcc aag cac cag      144
 Leu Gly Glu Gln Gly Arg Ser Asp Ala Leu Ala Leu Ala Lys His Gln
          35                  40                  45

 ggc aaa gtg gga tcc aaa ggc cac cag cat ctt tta aaa gtg aaa gtg      192
 Gly Lys Val Gly Ser Lys Gly His Gln His Leu Leu Lys Val Lys Val
      50                  55                  60

 act cga aag ctt caa gtt gtt aaa gcc agg gtc tat ggt tct aac aaa      240
 Thr Arg Lys Leu Gln Val Val Lys Ala Arg Val Tyr Gly Ser Asn Lys
  65                  70                  75                  80

 cta agc acc ctc tct ggg gac cac agg gtg cag tgg tta aga ctg ggg      288
 Leu Ser Thr Leu Ser Gly Asp His Arg Val Gln Trp Leu Arg Leu Gly
                  85                  90                  95

 gct cag gag ccc ttc tac ctg ggg gta gat gct ggc tct aac tct tac      336
 Ala Gln Glu Pro Phe Tyr Leu Gly Val Asp Ala Gly Ser Asn Ser Tyr
             100                 105                 110

 aaa tac ctg tga                                                      348
 Lys Tyr Leu 
         115





      <210> 940
      <211> 174
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(174)

      <400> 940
  atg ttg atg ttt gtg att ttc gtt att tat acg aag agc gag ctg gtt      48
  Met Leu Met Phe Val Ile Phe Val Ile Tyr Thr Lys Ser Glu Leu Val
    1               5                  10                  15

 ttc tta cca aac tgg aaa cct agc tgt ttg aac tat gat gac ata tct       96
 Phe Leu Pro Asn Trp Lys Pro Ser Cys Leu Asn Tyr Asp Asp Ile Ser
              20                  25                  30

 aac ata ttc tac ctt ttt gga gtt tat ctt gaa cca aga aaa att atg      144
 Asn Ile Phe Tyr Leu Phe Gly Val Tyr Leu Glu Pro Arg Lys Ile Met
          35                  40                  45

 gga gga aat aac agc tca ttg ctt gat taa                              174
 Gly Gly Asn Asn Ser Ser Leu Leu Asp 
      50                  55





      <210> 941
      <211> 141
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(141)

      <400> 941
  atg aac agg gtg atg agg ggt ctg gcc atc acc acc acc tgc ctc ctg      48
  Met Asn Arg Val Met Arg Gly Leu Ala Ile Thr Thr Thr Cys Leu Leu
    1               5                  10                  15

 agc atg ctc cag gcc atc acc atc agc cct agc atc ttg tgg aat cat       96
 Ser Met Leu Gln Ala Ile Thr Ile Ser Pro Ser Ile Leu Trp Asn His
              20                  25                  30

 gct gct gtc cag tat gta cac ggt cat tct ctt gtt cag gca tga          141
 Ala Ala Val Gln Tyr Val His Gly His Ser Leu Val Gln Ala 
          35                  40                  45





      <210> 942
      <211> 1176
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1176)

      <400> 942
  atg ggc cta ctt ccc cgg tcg ccc ctg tgg ctg gct gtg gct ctg ccg      48
  Met Gly Leu Leu Pro Arg Ser Pro Leu Trp Leu Ala Val Ala Leu Pro
    1               5                  10                  15

 ggg caa cca cgg gcc gtc gct gtg ggt gca cac agc atg cat ttc ttc       96
 Gly Gln Pro Arg Ala Val Ala Val Gly Ala His Ser Met His Phe Phe
              20                  25                  30

 aac aag cgg act cag aag gca ctt gca cat cgt tgc tgt tct gcc tct      144
 Asn Lys Arg Thr Gln Lys Ala Leu Ala His Arg Cys Cys Ser Ala Ser
          35                  40                  45

 ttg ctt cag cat gat tac cca gag gcg cac ccg tgc cgt ggc ctg ccc      192
 Leu Leu Gln His Asp Tyr Pro Glu Ala His Pro Cys Arg Gly Leu Pro
      50                  55                  60

 gtc gtc tat gca ccc gtg ctg tgg cgt gcc cgt cgt ctg tgt ggc atg      240
 Val Val Tyr Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Gly Met
  65                  70                  75                  80

 cct gtc tgt gca ccc gtg ctg tgg cgt gcc cgt cgt ctg tgt ggc atg      288
 Pro Val Cys Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Gly Met
                  85                  90                  95

 cct gtc tgt gca ccc gtg ctg tgg cgt gcc cgt cgt ctg tgc acc cgt      336
 Pro Val Cys Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Thr Arg
             100                 105                 110

 gct gtg gtg tgc ccg tcg tct gtg cac ccg tgc cgt ggc gtg ccc gtc      384
 Ala Val Val Cys Pro Ser Ser Val His Pro Cys Arg Gly Val Pro Val
         115                 120                 125

 gtc tgt gca ccc gtg ctg tgg gtt gca ccc aca tgt gca agc cag cga      432
 Val Cys Ala Pro Val Leu Trp Val Ala Pro Thr Cys Ala Ser Gln Arg
     130                 135                 140

 cgg acc cca ggt tca ccc gtt cac cgg tca gtg ggc ata tgg gtt gtt      480
 Arg Thr Pro Gly Ser Pro Val His Arg Ser Val Gly Ile Trp Val Val
 145                 150                 155                 160

 tca gtt tgg ggc att tac aag aaa cgt gct aga aca ttt gtg tac aag      528
 Ser Val Trp Gly Ile Tyr Lys Lys Arg Ala Arg Thr Phe Val Tyr Lys
                 165                 170                 175

 tct tgt gtg aac cta agt tca ttt ctc ttg ggt aaa tac ctg tgc gtg      576
 Ser Cys Val Asn Leu Ser Ser Phe Leu Leu Gly Lys Tyr Leu Cys Val
             180                 185                 190

 gag cag ctg ggt cat gtg gtg aat cag cat gtg gtg tgg ttg gtc ttt      624
 Glu Gln Leu Gly His Val Val Asn Gln His Val Val Trp Leu Val Phe
         195                 200                 205

 ttc gtg gca gcc agt cca ctg ggt gcg ctc ggc atg tgg ctg cag ctt      672
 Phe Val Ala Ala Ser Pro Leu Gly Ala Leu Gly Met Trp Leu Gln Leu
     210                 215                 220

 gac ctg ggt ttc ctg gtc cct ggc aag gtg gag cat ctc ttc atg tgc      720
 Asp Leu Gly Phe Leu Val Pro Gly Lys Val Glu His Leu Phe Met Cys
 225                 230                 235                 240

 ttt ttt gct gtg tgt gga tct tgc ggg gaa agg gat gcc agc ctc aca      768
 Phe Phe Ala Val Cys Gly Ser Cys Gly Glu Arg Asp Ala Ser Leu Thr
                 245                 250                 255

 ccg tgg ctc ttc cgg aag gtg tgg ggc cag gcc tgc tgc act tac tgc      816
 Pro Trp Leu Phe Arg Lys Val Trp Gly Gln Ala Cys Cys Thr Tyr Cys
             260                 265                 270

 ttt ggg cta atg att cag aga gtg aag ggt gct ttc tcc cca gag gaa      864
 Phe Gly Leu Met Ile Gln Arg Val Lys Gly Ala Phe Ser Pro Glu Glu
         275                 280                 285

 gga gcg aag gcc ttt gca gga gat gac aca ctg acg aag gtt tcc cat      912
 Gly Ala Lys Ala Phe Ala Gly Asp Asp Thr Leu Thr Lys Val Ser His
     290                 295                 300

 gcc ctc tcc aag aaa act gat gga caa cgg ggc tgc atc ctg ggc ggg      960
 Ala Leu Ser Lys Lys Thr Asp Gly Gln Arg Gly Cys Ile Leu Gly Gly
 305                 310                 315                 320

 ggc tta cct ggg aac cac gtg gga cca ggt ccg gag aac cat cct cta     1008
 Gly Leu Pro Gly Asn His Val Gly Pro Gly Pro Glu Asn His Pro Leu
                 325                 330                 335

 gcc agc tcg tct tgg caa gtg tcg tcc aac cca gtg cta gct gat aga     1056
 Ala Ser Ser Ser Trp Gln Val Ser Ser Asn Pro Val Leu Ala Asp Arg
             340                 345                 350

 acc ttc tgc aac gat ggg aat gtt ctg tac ctg gat aac ccc ctg gca     1104
 Thr Phe Cys Asn Asp Gly Asn Val Leu Tyr Leu Asp Asn Pro Leu Ala
         355                 360                 365

 cag atg act act ggg tac tgg aaa tgt ggc cac aag gaa cca aat ttt     1152
 Gln Met Thr Thr Gly Tyr Trp Lys Cys Gly His Lys Glu Pro Asn Phe
     370                 375                 380

 tca ttg tgt ttc atc gta att taa                                     1176
 Ser Leu Cys Phe Ile Val Ile 
 385                 390





      <210> 943
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 943
  atg ctg atg cta att ttg gta aca gga gtg tca tct ttg agg aat atg      48
  Met Leu Met Leu Ile Leu Val Thr Gly Val Ser Ser Leu Arg Asn Met
    1               5                  10                  15

 att atg tgt gat tat att agc aga gca aag ctg aag tct agt cac att       96
 Ile Met Cys Asp Tyr Ile Ser Arg Ala Lys Leu Lys Ser Ser His Ile
              20                  25                  30

 gta ctc tca tat tgt agc ctg aag caa gaa tat gat gac agc agg gga      144
 Val Leu Ser Tyr Cys Ser Leu Lys Gln Glu Tyr Asp Asp Ser Arg Gly
          35                  40                  45

 gtg atg aac ttg gag gct aga gaa gag gga agc aga ggc ttc tac tgc      192
 Val Met Asn Leu Glu Ala Arg Glu Glu Gly Ser Arg Gly Phe Tyr Cys
      50                  55                  60

 ctc ggc tgc att gat act ggc ttg caa act ccc gga gga aga ggc cca      240
 Leu Gly Cys Ile Asp Thr Gly Leu Gln Thr Pro Gly Gly Arg Gly Pro
  65                  70                  75                  80

 tca tct gct ttg gtc act tca gtg cac ctt gct tgc gaa gag tac act      288
 Ser Ser Ala Leu Val Thr Ser Val His Leu Ala Cys Glu Glu Tyr Thr
                  85                  90                  95

 ttt cat agg gag att gaa gat gat gct gac tga                          321
 Phe His Arg Glu Ile Glu Asp Asp Ala Asp 
             100                 105





      <210> 944
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 944
  atg gcc acc tgc atg cca gtc ctt cgt gta ttg ctg tgt atg tgc gcc      48
  Met Ala Thr Cys Met Pro Val Leu Arg Val Leu Leu Cys Met Cys Ala
    1               5                  10                  15

 ctt cct tgg atg aaa gga aga agt gac aag tct aaa ctg aag aag ttg       96
 Leu Pro Trp Met Lys Gly Arg Ser Asp Lys Ser Lys Leu Lys Lys Leu
              20                  25                  30

 aca tca gag ggc cag tgg aat gga atc tta gtt cag ttc cca caa aag      144
 Thr Ser Glu Gly Gln Trp Asn Gly Ile Leu Val Gln Phe Pro Gln Lys
          35                  40                  45

 gag gat ttc ttg gta cca aga gat aaa ata aat atg aat tgg ggg gct      192
 Glu Asp Phe Leu Val Pro Arg Asp Lys Ile Asn Met Asn Trp Gly Ala
      50                  55                  60

 ggg gca gga ctt caa agg gag ttt gct gca agt gcc aga aat gtg gcc      240
 Gly Ala Gly Leu Gln Arg Glu Phe Ala Ala Ser Ala Arg Asn Val Ala
  65                  70                  75                  80

 acc agg cca agg aat gcc tgc agc cca aga ttc ctc cta agc cgt gtc      288
 Thr Arg Pro Arg Asn Ala Cys Ser Pro Arg Phe Leu Leu Ser Arg Val
                  85                  90                  95

 cca tct gtg cgg gac ccc act ggc aat cgg act gtc caa ctc acc tgg      336
 Pro Ser Val Arg Asp Pro Thr Gly Asn Arg Thr Val Gln Leu Thr Trp
             100                 105                 110

 cag cca ctc cca gag tcc ctg gaa ctc tgg ccc aag gct ctc tga          381
 Gln Pro Leu Pro Glu Ser Leu Glu Leu Trp Pro Lys Ala Leu 
         115                 120                 125





      <210> 945
      <211> 240
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(240)

      <400> 945
  atg gtg gac atg ttt gga aag aaa gct ttt ttt ctg tgc tgt ggg ctt      48
  Met Val Asp Met Phe Gly Lys Lys Ala Phe Phe Leu Cys Cys Gly Leu
    1               5                  10                  15

 gct atc cta gct ttc caa gct atc cta gtt ttg caa att tct ctg atc       96
 Ala Ile Leu Ala Phe Gln Ala Ile Leu Val Leu Gln Ile Ser Leu Ile
              20                  25                  30

 aat cac atc agg ttc ttg gat cat ccc aaa att aaa gag gtg aag ccc      144
 Asn His Ile Arg Phe Leu Asp His Pro Lys Ile Lys Glu Val Lys Pro
          35                  40                  45

 gca tcc aat gac tgc tca gtg tgg gta tat aaa ggc ctg gct ccc ttg      192
 Ala Ser Asn Asp Cys Ser Val Trp Val Tyr Lys Gly Leu Ala Pro Leu
      50                  55                  60

 cca gtg cca ccc tac ctc ctg gcg aat gga ctg agg ctt gca tta tga      240
 Pro Val Pro Pro Tyr Leu Leu Ala Asn Gly Leu Arg Leu Ala Leu 
  65                  70                  75





      <210> 946
      <211> 726
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(726)

      <400> 946
  atg gtc aat ccc act atg ttg ggg ttg aca gtg cgg ttg atg gtg ggc      48
  Met Val Asn Pro Thr Met Leu Gly Leu Thr Val Arg Leu Met Val Gly
    1               5                  10                  15

 cct tgt gtc tcc ttt gag ctg ttg gca gac aag ttt cca aag aca gca       96
 Pro Cys Val Ser Phe Glu Leu Leu Ala Asp Lys Phe Pro Lys Thr Ala
              20                  25                  30

 gaa aaa ttt cgt gct cta agc cct gga gag gaa gga ttt ggt tat aag      144
 Glu Lys Phe Arg Ala Leu Ser Pro Gly Glu Glu Gly Phe Gly Tyr Lys
          35                  40                  45

 ggt tca tgc ttt cac aga att att cca ggg ttt atg tgt caa ggt ggt      192
 Gly Ser Cys Phe His Arg Ile Ile Pro Gly Phe Met Cys Gln Gly Gly
      50                  55                  60

 gac ttc aca ctc cat aat ggc act ggt ggc aac tcc atc tat gga gag      240
 Asp Phe Thr Leu His Asn Gly Thr Gly Gly Asn Ser Ile Tyr Gly Glu
  65                  70                  75                  80

 aaa tta gat gat gag aac ttc atc cta aag cat ata gga cag ttg tgg      288
 Lys Leu Asp Asp Glu Asn Phe Ile Leu Lys His Ile Gly Gln Leu Trp
                  85                  90                  95

 atc tgt agg cca aaa gga gag aag gaa ggg gaa cca cct ctt cct ggg      336
 Ile Cys Arg Pro Lys Gly Glu Lys Glu Gly Glu Pro Pro Leu Pro Gly
             100                 105                 110

 ctc tgt agc tta cgc ccc tca aat gta caa gaa gga cag gag cag aat      384
 Leu Cys Ser Leu Arg Pro Ser Asn Val Gln Glu Gly Gln Glu Gln Asn
         115                 120                 125

 ctc cga ggg tcc tgt gtg atg gcg ctc agc act ggg gaa aca cga caa      432
 Leu Arg Gly Ser Cys Val Met Ala Leu Ser Thr Gly Glu Thr Arg Gln
     130                 135                 140

 tat gga ctt tgg agt cag gca aac cgg agt ttg cag cct agc tat ggc      480
 Tyr Gly Leu Trp Ser Gln Ala Asn Arg Ser Leu Gln Pro Ser Tyr Gly
 145                 150                 155                 160

 act gac agg ctg tgt gac tct gga aag cta ctt cat ctc tct gag cct      528
 Thr Asp Arg Leu Cys Asp Ser Gly Lys Leu Leu His Leu Ser Glu Pro
                 165                 170                 175

 cag cga act cac atg caa aca gag acc ata gca agg ctt gtg tct gtc      576
 Gln Arg Thr His Met Gln Thr Glu Thr Ile Ala Arg Leu Val Ser Val
             180                 185                 190

 atc agc aat act ctc caa atg agg ggc acc atg cat ggc cac agg aca      624
 Ile Ser Asn Thr Leu Gln Met Arg Gly Thr Met His Gly His Arg Thr
         195                 200                 205

 acc cat agc cca cag act gac aca ctg ttt gag agt tgg act cca gca      672
 Thr His Ser Pro Gln Thr Asp Thr Leu Phe Glu Ser Trp Thr Pro Ala
     210                 215                 220

 acc gtg gag ccg tcc agt cca cca gat ggc aaa gtc ccc ttc aca ggg      720
 Thr Val Glu Pro Ser Ser Pro Pro Asp Gly Lys Val Pro Phe Thr Gly
 225                 230                 235                 240

 ctc taa                                                              726
 Leu 






      <210> 947
      <211> 1368
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1368)

      <400> 947
  atg tgg ctg tcc cca tct ctg ctg ctt ctc atc ctc cca gct gca tta      48
  Met Trp Leu Ser Pro Ser Leu Leu Leu Leu Ile Leu Pro Ala Ala Leu
    1               5                  10                  15

 agt gat gca ggg gtg gtc ctg ggg gcc ggc tcc ctg gtt ctc ccc tcc       96
 Ser Asp Ala Gly Val Val Leu Gly Ala Gly Ser Leu Val Leu Pro Ser
              20                  25                  30

 aat gcc cag aga caa ccc tat gca caa cca gga cct cag ttg cct ggg      144
 Asn Ala Gln Arg Gln Pro Tyr Ala Gln Pro Gly Pro Gln Leu Pro Gly
          35                  40                  45

 gca gaa gtg ttg atg gag aag tgg gtt aac ata agg cag cag ctc gac      192
 Ala Glu Val Leu Met Glu Lys Trp Val Asn Ile Arg Gln Gln Leu Asp
      50                  55                  60

 tct gcc aga gct ggc ttt gca ggg aag ctt tat cgg cat ttt gaa gga      240
 Ser Ala Arg Ala Gly Phe Ala Gly Lys Leu Tyr Arg His Phe Glu Gly
  65                  70                  75                  80

 tgt gta ggg gct cca ggt atc aag gaa ggc aga cta tct cag tca gct      288
 Cys Val Gly Ala Pro Gly Ile Lys Glu Gly Arg Leu Ser Gln Ser Ala
                  85                  90                  95

 cag gct gct ata aca aag ata cca cag att ggg tgg ctc aca caa aag      336
 Gln Ala Ala Ile Thr Lys Ile Pro Gln Ile Gly Trp Leu Thr Gln Lys
             100                 105                 110

 aaa ttc att tct ccc agt tct ggt ggc tgg aag ttc aag atc aag atg      384
 Lys Phe Ile Ser Pro Ser Ser Gly Gly Trp Lys Phe Lys Ile Lys Met
         115                 120                 125

 ctg gct gaa tca gtt cct ggc aca ttt cat tat aat cca att aga aaa      432
 Leu Ala Glu Ser Val Pro Gly Thr Phe His Tyr Asn Pro Ile Arg Lys
     130                 135                 140

 tcc aaa ctc cga cca cct agt aag acc gag ttg aca cag aag cta tca      480
 Ser Lys Leu Arg Pro Pro Ser Lys Thr Glu Leu Thr Gln Lys Leu Ser
 145                 150                 155                 160

 tct ggt tcc aaa ctg aag tca aat cca ata aaa gga aat tcc agg ctg      528
 Ser Gly Ser Lys Leu Lys Ser Asn Pro Ile Lys Gly Asn Ser Arg Leu
                 165                 170                 175

 tca cta aag ctg ctg ccc gtg gaa ctg cac aga gct cag gaa att tcc      576
 Ser Leu Lys Leu Leu Pro Val Glu Leu His Arg Ala Gln Glu Ile Ser
             180                 185                 190

 tcc tcc ata gat aag aga aac tta gaa gct cta ttt atc tca tac atc      624
 Ser Ser Ile Asp Lys Arg Asn Leu Glu Ala Leu Phe Ile Ser Tyr Ile
         195                 200                 205

 ctg gag aga att gtc cag gga caa aaa cag aag cgc cgc cag cgc cgc      672
 Leu Glu Arg Ile Val Gln Gly Gln Lys Gln Lys Arg Arg Gln Arg Arg
     210                 215                 220

 agg act tcg cct ctg caa acg tgt gag gag agc tgc gct gcg ctg agc      720
 Arg Thr Ser Pro Leu Gln Thr Cys Glu Glu Ser Cys Ala Ala Leu Ser
 225                 230                 235                 240

 tgc gtg gtg acg gag atg ccc gtt cgc tcg gga tca gga acg gtg agc      768
 Cys Val Val Thr Glu Met Pro Val Arg Ser Gly Ser Gly Thr Val Ser
                 245                 250                 255

 tcc tgg gac cgc aat gcc ctg aga acg cag ccg gca tcc tgg agt cct      816
 Ser Trp Asp Arg Asn Ala Leu Arg Thr Gln Pro Ala Ser Trp Ser Pro
             260                 265                 270

 aag agg cag gga ttg gag cgg aca gga tct cag aac tct ggt ccc ggg      864
 Lys Arg Gln Gly Leu Glu Arg Thr Gly Ser Gln Asn Ser Gly Pro Gly
         275                 280                 285

 cgc aca acg gcg gag tcg ctg ttc ctg gtg ctg aaa cgc tca gtc ctg      912
 Arg Thr Thr Ala Glu Ser Leu Phe Leu Val Leu Lys Arg Ser Val Leu
     290                 295                 300

 gaa gaa cgt ggc cgc ctg ccc gcc tgg tac cgc gcc gcg gcc gct gcg      960
 Glu Glu Arg Gly Arg Leu Pro Ala Trp Tyr Arg Ala Ala Ala Ala Ala
 305                 310                 315                 320

 ggg aac tgt cca gtg ctg aaa acg gat gcg gcc cgg ccc gca gag ctc     1008
 Gly Asn Cys Pro Val Leu Lys Thr Asp Ala Ala Arg Pro Ala Glu Leu
                 325                 330                 335

 aga ccc aag cct gcc gca ccc agc gga gct cga acc gag ctc ctg gaa     1056
 Arg Pro Lys Pro Ala Ala Pro Ser Gly Ala Arg Thr Glu Leu Leu Glu
             340                 345                 350

 gcg ctg acg cag agc gca ggg aga gcc gga gcg gcg agc tcc aag cct     1104
 Ala Leu Thr Gln Ser Ala Gly Arg Ala Gly Ala Ala Ser Ser Lys Pro
         355                 360                 365

 ggc atg gac ctg cag aga ccc gat tcc tac cag gga gga gct ggc cct     1152
 Gly Met Asp Leu Gln Arg Pro Asp Ser Tyr Gln Gly Gly Ala Gly Pro
     370                 375                 380

 gac ttc aac gac cac gtc ctg cat aag gca aga gaa aca gtc tgt aga     1200
 Asp Phe Asn Asp His Val Leu His Lys Ala Arg Glu Thr Val Cys Arg
 385                 390                 395                 400

 gac tgc gag tgc gaa tgg aga tca cag ctc ctt gtt aac tca ctc agg     1248
 Asp Cys Glu Cys Glu Trp Arg Ser Gln Leu Leu Val Asn Ser Leu Arg
                 405                 410                 415

 caa tgt agt tcc cag ctg gga gtg gcc ctg gac atc ctc cta tct ctt     1296
 Gln Cys Ser Ser Gln Leu Gly Val Ala Leu Asp Ile Leu Leu Ser Leu
             420                 425                 430

 aac cag agg agg ttt tct ggg gcc aag aga gac agc tcc aag caa aca     1344
 Asn Gln Arg Arg Phe Ser Gly Ala Lys Arg Asp Ser Ser Lys Gln Thr
         435                 440                 445

 gat ctg gaa aat att aac ccc taa                                     1368
 Asp Leu Glu Asn Ile Asn Pro 
     450                 455





      <210> 948
      <211> 552
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(552)

      <400> 948
  atg aaa agg caa gac tgg cct atc ctg cca gcc tac atc ttt ctc ctg      48
  Met Lys Arg Gln Asp Trp Pro Ile Leu Pro Ala Tyr Ile Phe Leu Leu
    1               5                  10                  15

 tgc tgg atg ctt cct gcc ctg gaa cat cag act cca agt tct tca gtt       96
 Cys Trp Met Leu Pro Ala Leu Glu His Gln Thr Pro Ser Ser Ser Val
              20                  25                  30

 ttg aga ctt gaa ctg act ttc ctg ctc ctt aag ctt gca ggc agc cta      144
 Leu Arg Leu Glu Leu Thr Phe Leu Leu Leu Lys Leu Ala Gly Ser Leu
          35                  40                  45

 ttg cgg gac att gtg att gtg agc cat cct agc cct aac aca cag ctg      192
 Leu Arg Asp Ile Val Ile Val Ser His Pro Ser Pro Asn Thr Gln Leu
      50                  55                  60

 cga ctc tcc ggt ccg acc aga ggt ccc aga ctt gct ccc acg gca cgg      240
 Arg Leu Ser Gly Pro Thr Arg Gly Pro Arg Leu Ala Pro Thr Ala Arg
  65                  70                  75                  80

 gaa ctc ttt cgt ggc gaa gca gca ggt ggc gaa gca gca gcc cct gcg      288
 Glu Leu Phe Arg Gly Glu Ala Ala Gly Gly Glu Ala Ala Ala Pro Ala
                  85                  90                  95

 ctg cct cat cta cat aga aat cgc cct ttc cgt gat gtc acc gac aac      336
 Leu Pro His Leu His Arg Asn Arg Pro Phe Arg Asp Val Thr Asp Asn
             100                 105                 110

 gcc ttc tgg atc ccc gtc tgc tct tcc gcc tca ccc aac gcc cct cag      384
 Ala Phe Trp Ile Pro Val Cys Ser Ser Ala Ser Pro Asn Ala Pro Gln
         115                 120                 125

 tgg agc aac ccg ctg tcg gag ccg gcg ggg gaa gtg act tat gcc tgt      432
 Trp Ser Asn Pro Leu Ser Glu Pro Ala Gly Glu Val Thr Tyr Ala Cys
     130                 135                 140

 ccc ttc ttt ctc tcc tgt ccc cgc ccc tcg tct ccc gca atg aag cgg      480
 Pro Phe Phe Leu Ser Cys Pro Arg Pro Ser Ser Pro Ala Met Lys Arg
 145                 150                 155                 160

 gta ttt aat ctg tgt cct gtg gaa gtc cca ttt ggc ggc cag ctg gaa      528
 Val Phe Asn Leu Cys Pro Val Glu Val Pro Phe Gly Gly Gln Leu Glu
                 165                 170                 175

 gcc cgt gca ccc ttc ttc aaa taa                                      552
 Ala Arg Ala Pro Phe Phe Lys 
             180





      <210> 949
      <211> 285
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(285)

      <400> 949
  atg aca act tcg gtc gtg gag aaa ctt cag tgg gtc gtg gtg gct ttg      48
  Met Thr Thr Ser Val Val Glu Lys Leu Gln Trp Val Val Val Ala Leu
    1               5                  10                  15

 gtg gca gcc gtg gtg gtg gtg gat atg gtg gca gtg ggg atg gct ata       96
 Val Ala Ala Val Val Val Val Asp Met Val Ala Val Gly Met Ala Ile
              20                  25                  30

 atg gat ttg gta atg atg gtg gtt atg gag gag gcg gcc ctg gtt act      144
 Met Asp Leu Val Met Met Val Val Met Glu Glu Ala Ala Leu Val Thr
          35                  40                  45

 ctg gag gaa gca gag gct atg caa gtg gtg gac agg gtt atg gaa acc      192
 Leu Glu Glu Ala Glu Ala Met Gln Val Val Asp Arg Val Met Glu Thr
      50                  55                  60

 agg gca gtg gct atg gcg gga gtg gca gct atg aca gct ata aca acg      240
 Arg Ala Val Ala Met Ala Gly Val Ala Ala Met Thr Ala Ile Thr Thr
  65                  70                  75                  80

 gag gcg gag gcg gct ttg gcg gtg gta gtg gta ggt atc cag tga          285
 Glu Ala Glu Ala Ala Leu Ala Val Val Val Val Gly Ile Gln 
                  85                  90





      <210> 950
      <211> 657
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(657)

      <400> 950
  atg ccc cga ggg ctc ctg ctt gtg ttg cca gca cct gcc ctt ggg agc      48
  Met Pro Arg Gly Leu Leu Leu Val Leu Pro Ala Pro Ala Leu Gly Ser
    1               5                  10                  15

 cgt cag ctg ggg cca cga tgc tgg cag gct cag ccc gac ctg gcg ctg       96
 Arg Gln Leu Gly Pro Arg Cys Trp Gln Ala Gln Pro Asp Leu Ala Leu
              20                  25                  30

 cgg cgc cgt cct cgc ggt cct ccg gcg cgg cct ctc ctg gag ctg ggc      144
 Arg Arg Arg Pro Arg Gly Pro Pro Ala Arg Pro Leu Leu Glu Leu Gly
          35                  40                  45

 tgg gag tgg gcc ccg ggc ctc ggc act cgg cgg gtg gcg gcg tcg ccg      192
 Trp Glu Trp Ala Pro Gly Leu Gly Thr Arg Arg Val Ala Ala Ser Pro
      50                  55                  60

 ctg cgg gac tgt ggg act ccc agc tcg ggc cac cta cac act ggg aca      240
 Leu Arg Asp Cys Gly Thr Pro Ser Ser Gly His Leu His Thr Gly Thr
  65                  70                  75                  80

 cca tca cga gcc ctg aac tcc aga gca gac cca gca ggg ccg gga gcg      288
 Pro Ser Arg Ala Leu Asn Ser Arg Ala Asp Pro Ala Gly Pro Gly Ala
                  85                  90                  95

 cag agc ctg gac agc ggc cac ctg gtt ctc ccg atg ctg ctc agt gaa      336
 Gln Ser Leu Asp Ser Gly His Leu Val Leu Pro Met Leu Leu Ser Glu
             100                 105                 110

 ggc agc agc agg acc aga tca gtc cca cct gag aac ggc cac cgg ggc      384
 Gly Ser Ser Arg Thr Arg Ser Val Pro Pro Glu Asn Gly His Arg Gly
         115                 120                 125

 cgt ctg ttg aaa ggt cca ggc ccc tcc ctg gct gtt gaa ctc aga cac      432
 Arg Leu Leu Lys Gly Pro Gly Pro Ser Leu Ala Val Glu Leu Arg His
     130                 135                 140

 cac acc cag gtg tct ggg att gat ggt gca gga gga agc acc ttg ggc      480
 His Thr Gln Val Ser Gly Ile Asp Gly Ala Gly Gly Ser Thr Leu Gly
 145                 150                 155                 160

 ctg tta cag atg cgg ttc cca ccc gct gtg gac ggg ccg tgg gtc ccc      528
 Leu Leu Gln Met Arg Phe Pro Pro Ala Val Asp Gly Pro Trp Val Pro
                 165                 170                 175

 cca aga gga tgg tca ttc acg tct gag acc gtg cac agc gtg gcg gct      576
 Pro Arg Gly Trp Ser Phe Thr Ser Glu Thr Val His Ser Val Ala Ala
             180                 185                 190

 cgc agc ctg ctc ttg cct ttc gtc ctc tac agt gga acc tac tct ggc      624
 Arg Ser Leu Leu Leu Pro Phe Val Leu Tyr Ser Gly Thr Tyr Ser Gly
         195                 200                 205

 cct gga ctg gtt cag gat gga cag gga ctg tga                          657
 Pro Gly Leu Val Gln Asp Gly Gln Gly Leu 
     210                 215





      <210> 951
      <211> 402
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(402)

      <400> 951
  atg cct gtc ctt cct gtt gcc att gcc ctt gcc acc tta tgg act cta      48
  Met Pro Val Leu Pro Val Ala Ile Ala Leu Ala Thr Leu Trp Thr Leu
    1               5                  10                  15

 cgt cga aag tgc gca ggt ttg ggc aag aag gga tct cct cag tta gtg       96
 Arg Arg Lys Cys Ala Gly Leu Gly Lys Lys Gly Ser Pro Gln Leu Val
              20                  25                  30

 tta aga gct gga gct agg att gtg tta act cgt tca aga cac agc atg      144
 Leu Arg Ala Gly Ala Arg Ile Val Leu Thr Arg Ser Arg His Ser Met
          35                  40                  45

 gaa gaa gag ttt aca aca gat gaa gca gat gaa act agg agc aat gaa      192
 Glu Glu Glu Phe Thr Thr Asp Glu Ala Asp Glu Thr Arg Ser Asn Glu
      50                  55                  60

 acc cag aat cct cat aaa cca tca cct agc agg ctg tca aca ggt gca      240
 Thr Gln Asn Pro His Lys Pro Ser Pro Ser Arg Leu Ser Thr Gly Ala
  65                  70                  75                  80

 tct gct gat gct gtc tgg gat aat ggc att gat gat gct tat ttt tta      288
 Ser Ala Asp Ala Val Trp Asp Asn Gly Ile Asp Asp Ala Tyr Phe Leu
                  85                  90                  95

 gaa gct act gaa gat gct gaa tta gct gaa gct gca gag aac agt ctt      336
 Glu Ala Thr Glu Asp Ala Glu Leu Ala Glu Ala Ala Glu Asn Ser Leu
             100                 105                 110

 ctc agt tat aac agt gaa gtg gat gaa att cct gat gaa cta att ata      384
 Leu Ser Tyr Asn Ser Glu Val Asp Glu Ile Pro Asp Glu Leu Ile Ile
         115                 120                 125

 gaa gta tta caa gag taa                                              402
 Glu Val Leu Gln Glu 
     130





      <210> 952
      <211> 678
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(678)

      <400> 952
  atg gag cac gtt gcc cac gtg ccc cta gag atc tca gaa ggt gga ggg      48
  Met Glu His Val Ala His Val Pro Leu Glu Ile Ser Glu Gly Gly Gly
    1               5                  10                  15

 ctt gtg gaa gac ccc aca cca gca gca gaa tgg gcc ttg cct ctg ggc       96
 Leu Val Glu Asp Pro Thr Pro Ala Ala Glu Trp Ala Leu Pro Leu Gly
              20                  25                  30

 tct gtc acc ctg aca ctc aaa gtg ctc cta ctg cta cac cta ctc ttg      144
 Ser Val Thr Leu Thr Leu Lys Val Leu Leu Leu Leu His Leu Leu Leu
          35                  40                  45

 atc tta gaa agc tct gcc ctg ctc caa att gtc aac tgt gtc gtc agg      192
 Ile Leu Glu Ser Ser Ala Leu Leu Gln Ile Val Asn Cys Val Val Arg
      50                  55                  60

 gtg gct tca ctt gtg gta gca aaa tgt ctg cag cag ttc caa gcc tca      240
 Val Ala Ser Leu Val Val Ala Lys Cys Leu Gln Gln Phe Gln Ala Ser
  65                  70                  75                  80

 gat ctg cac att atg acc tct gga gca agt gcg atc tct cca acc acc      288
 Asp Leu His Ile Met Thr Ser Gly Ala Ser Ala Ile Ser Pro Thr Thr
                  85                  90                  95

 aaa tgg gag cct tct cac aac tct gct tgc acc cag cct caa tca acc      336
 Lys Trp Glu Pro Ser His Asn Ser Ala Cys Thr Gln Pro Gln Ser Thr
             100                 105                 110

 act ttg gcc agg gtg ccc tgc tgg ctg ctg agt gga gaa gaa ggt gga      384
 Thr Leu Ala Arg Val Pro Cys Trp Leu Leu Ser Gly Glu Glu Gly Gly
         115                 120                 125

 gag atg aag cat cct cag aaa tgc agc aag gcg gcc atg gca gtg aca      432
 Glu Met Lys His Pro Gln Lys Cys Ser Lys Ala Ala Met Ala Val Thr
     130                 135                 140

 tta gtg gcc cag acc aga gag gca gga agc cct caa aga gtc cac ctg      480
 Leu Val Ala Gln Thr Arg Glu Ala Gly Ser Pro Gln Arg Val His Leu
 145                 150                 155                 160

 gag act tat gca cca ata tac tgt gcc caa cac agg agc ttc ctg ctg      528
 Glu Thr Tyr Ala Pro Ile Tyr Cys Ala Gln His Arg Ser Phe Leu Leu
                 165                 170                 175

 gga gac acc cct tca tcc gga gct gaa gaa gcc aaa gag gtt cct tct      576
 Gly Asp Thr Pro Ser Ser Gly Ala Glu Glu Ala Lys Glu Val Pro Ser
             180                 185                 190

 ccc ctc tca ggc tcc ctc acc ttc cct cac ctt cca ccc aaa gat att      624
 Pro Leu Ser Gly Ser Leu Thr Phe Pro His Leu Pro Pro Lys Asp Ile
         195                 200                 205

 agg aga att aat ggg ata aca gat gta atg cct cca agg aaa cgg gcc      672
 Arg Arg Ile Asn Gly Ile Thr Asp Val Met Pro Pro Arg Lys Arg Ala
     210                 215                 220

 aca taa                                                              678
 Thr 
 225





      <210> 953
      <211> 423
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(423)

      <400> 953
  atg ttg agg tgg gtg tac att att tgt gcc ata tgc aat tgt tat atc      48
  Met Leu Arg Trp Val Tyr Ile Ile Cys Ala Ile Cys Asn Cys Tyr Ile
    1               5                  10                  15

 cca ggc atc aat gat act cac act gag atc ctg gaa aat gtc ctt tat       96
 Pro Gly Ile Asn Asp Thr His Thr Glu Ile Leu Glu Asn Val Leu Tyr
              20                  25                  30

 gat gag ata ttg aat gta acc atg aaa gtc act aaa tct ttc tgc atc      144
 Asp Glu Ile Leu Asn Val Thr Met Lys Val Thr Lys Ser Phe Cys Ile
          35                  40                  45

 att gta cat ctc cct gat gtt ttc tgt ttt gat gat aac cat agt gtc      192
 Ile Val His Leu Pro Asp Val Phe Cys Phe Asp Asp Asn His Ser Val
      50                  55                  60

 tgg gct tct cag aag aag atg ctg aat ggc ttt gtg gac att gag ggc      240
 Trp Ala Ser Gln Lys Lys Met Leu Asn Gly Phe Val Asp Ile Glu Gly
  65                  70                  75                  80

 cct tcg gat aaa aac atc aat ggg aaa ggg tct gaa atg ctg gcc cag      288
 Pro Ser Asp Lys Asn Ile Asn Gly Lys Gly Ser Glu Met Leu Ala Gln
                  85                  90                  95

 gga aat aac aat gac agt att ttt ttc tcc tcc agt tct gtc aat ggc      336
 Gly Asn Asn Asn Asp Ser Ile Phe Phe Ser Ser Ser Ser Val Asn Gly
             100                 105                 110

 ccg gat aag cca gat gaa cag agt gct gat agg act gaa aca gtg aac      384
 Pro Asp Lys Pro Asp Glu Gln Ser Ala Asp Arg Thr Glu Thr Val Asn
         115                 120                 125

 aaa tcc agt aga aag aag aaa ccc ttt aaa tgg gtc tag                  423
 Lys Ser Ser Arg Lys Lys Lys Pro Phe Lys Trp Val 
     130                 135                 140





      <210> 954
      <211> 237
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(237)

      <400> 954
  atg ggc ttc ggc ctc gtc ctt gct cct ctg tgc aat cag ttc ata ctg      48
  Met Gly Phe Gly Leu Val Leu Ala Pro Leu Cys Asn Gln Phe Ile Leu
    1               5                  10                  15

 ggt ccg cac tgc atc gat gat gct gtc cag gtc cag gga acg gtt att       96
 Gly Pro His Cys Ile Asp Asp Ala Val Gln Val Gln Gly Thr Val Ile
              20                  25                  30

 gtc cat gga cag gat gac gtt ggt gtc gct gat gac gac aaa gtc att      144
 Val His Gly Gln Asp Asp Val Gly Val Ala Asp Asp Asp Lys Val Ile
          35                  40                  45

 ctc gct gcc agt cct ctt gtt gat ttc atc ctc ata cct gtc agg cga      192
 Leu Ala Ala Ser Pro Leu Val Asp Phe Ile Leu Ile Pro Val Arg Arg
      50                  55                  60

 ggc aaa gga gca cag aaa ggc tgc agg ctg acc ttg gct ccc tga          237
 Gly Lys Gly Ala Gln Lys Gly Cys Arg Leu Thr Leu Ala Pro 
  65                  70                  75





      <210> 955
      <211> 477
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(477)

      <400> 955
  atg gtg gca tat cta aag agt ttg cag agc gga ctg acg ctc ctc ccc      48
  Met Val Ala Tyr Leu Lys Ser Leu Gln Ser Gly Leu Thr Leu Leu Pro
    1               5                  10                  15

 ttt ctc ttt aac gcc gaa gga ctt ggt gca gtt cgt gtg aat ctc aca       96
 Phe Leu Phe Asn Ala Glu Gly Leu Gly Ala Val Arg Val Asn Leu Thr
              20                  25                  30

 ggg gga atg caa ctg ttt gat ttt tcc agc cgg gat ggg gtt cat ctt      144
 Gly Gly Met Gln Leu Phe Asp Phe Ser Ser Arg Asp Gly Val His Leu
          35                  40                  45

 atg gag gac gtt gaa gtg agt cgc tct tta gtc ccc gag tgg aat gag      192
 Met Glu Asp Val Glu Val Ser Arg Ser Leu Val Pro Glu Trp Asn Glu
      50                  55                  60

 tgg ggg ttg ggg ggt tcc ctg gga acg cag ctt gga ggc agt ttc aga      240
 Trp Gly Leu Gly Gly Ser Leu Gly Thr Gln Leu Gly Gly Ser Phe Arg
  65                  70                  75                  80

 tgg tcc ccg aca gga gag gcg agc aaa gaa att cag tca tcc gga aag      288
 Trp Ser Pro Thr Gly Glu Ala Ser Lys Glu Ile Gln Ser Ser Gly Lys
                  85                  90                  95

 cag aac gcg aaa gcc agt gtg gcc gga cct att att tcc ctg caa ggt      336
 Gln Asn Ala Lys Ala Ser Val Ala Gly Pro Ile Ile Ser Leu Gln Gly
             100                 105                 110

 ggc gtg agt cgg gag gat gga atg ggg aag aat cct gat gat agt aag      384
 Gly Val Ser Arg Glu Asp Gly Met Gly Lys Asn Pro Asp Asp Ser Lys
         115                 120                 125

 gcc aaa ata tca acg cta gtt ggg ctc ctg agt gac cac ata aag aac      432
 Ala Lys Ile Ser Thr Leu Val Gly Leu Leu Ser Asp His Ile Lys Asn
     130                 135                 140

 agt ggt cct tat gag tcg cct aaa ctc aca gtg gat gtt gta tga          477
 Ser Gly Pro Tyr Glu Ser Pro Lys Leu Thr Val Asp Val Val 
 145                 150                 155





      <210> 956
      <211> 756
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(756)

      <400> 956
  atg ggc aag aag ctc agc cat cta gga gtt ggg gtt tta agt gtg acc      48
  Met Gly Lys Lys Leu Ser His Leu Gly Val Gly Val Leu Ser Val Thr
    1               5                  10                  15

 gcc caa ttc gcc tta ctt gct gcc ctg caa ata aat gcc ttc ctt tca       96
 Ala Gln Phe Ala Leu Leu Ala Ala Leu Gln Ile Asn Ala Phe Leu Ser
              20                  25                  30

 tct gct gca aac ctt ggt gtg gac gtt ttg gcc tta ctc tgc cag ttt      144
 Ser Ala Ala Asn Leu Gly Val Asp Val Leu Ala Leu Leu Cys Gln Phe
          35                  40                  45

 ttt ctc tgg ccc aat ctc acg ctg aca acc act ggc tcc acg agc cag      192
 Phe Leu Trp Pro Asn Leu Thr Leu Thr Thr Thr Gly Ser Thr Ser Gln
      50                  55                  60

 acc ttc agg aag gca tta gag cag ttc ccc gag agg atc ccc agt gga      240
 Thr Phe Arg Lys Ala Leu Glu Gln Phe Pro Glu Arg Ile Pro Ser Gly
  65                  70                  75                  80

 act atc agg cag att ccc cag tca gct cct gac att ata aaa aag ctt      288
 Thr Ile Arg Gln Ile Pro Gln Ser Ala Pro Asp Ile Ile Lys Lys Leu
                  85                  90                  95

 caa aaa tta gaa acc ggc cct caa acc cca caa cag gaa tta atc aac      336
 Gln Lys Leu Glu Thr Gly Pro Gln Thr Pro Gln Gln Glu Leu Ile Asn
             100                 105                 110

 ctc gcc ttc aag gtg tac aat aac aga gag gag gca gcc aga cag caa      384
 Leu Ala Phe Lys Val Tyr Asn Asn Arg Glu Glu Ala Ala Arg Gln Gln
         115                 120                 125

 cgc att tct gag tta caa tta ctt gcc tct gct atg aga caa aac cca      432
 Arg Ile Ser Glu Leu Gln Leu Leu Ala Ser Ala Met Arg Gln Asn Pro
     130                 135                 140

 gcc aca cct cca gca cac aag aac ttc aaa atg cct aag ctg cac aag      480
 Ala Thr Pro Pro Ala His Lys Asn Phe Lys Met Pro Lys Leu His Lys
 145                 150                 155                 160

 cct aag ccg cac acg cct aag ccg cag cag tca agc att cct aca gga      528
 Pro Lys Pro His Thr Pro Lys Pro Gln Gln Ser Ser Ile Pro Thr Gly
                 165                 170                 175

 ctt cct cca aca gga tct tgc ttc aag tgc cag aaa tct ggc cac tgg      576
 Leu Pro Pro Thr Gly Ser Cys Phe Lys Cys Gln Lys Ser Gly His Trp
             180                 185                 190

 gcc aag gaa tgc ccg cag ccc gga att cct ccc aag cca tgt ccc atc      624
 Ala Lys Glu Cys Pro Gln Pro Gly Ile Pro Pro Lys Pro Cys Pro Ile
         195                 200                 205

 tgt gca ggg acc cac tgg aaa tca gac tgc cca gct ctc ccg gca gcc      672
 Cys Ala Gly Thr His Trp Lys Ser Asp Cys Pro Ala Leu Pro Ala Ala
     210                 215                 220

 act tct aga gcc cct aaa gct cta gcc caa ggc tct ctg act gac tcc      720
 Thr Ser Arg Ala Pro Lys Ala Leu Ala Gln Gly Ser Leu Thr Asp Ser
 225                 230                 235                 240

 ttc cca gat ctg ctc ggc tta gtg gtt gaa gac tga                      756
 Phe Pro Asp Leu Leu Gly Leu Val Val Glu Asp 
                 245                 250





      <210> 957
      <211> 561
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(561)

      <400> 957
  atg gcg cag cat cgg tgt gct ttg tgc gtc tgc gcc atc ttc cgg ctg      48
  Met Ala Gln His Arg Cys Ala Leu Cys Val Cys Ala Ile Phe Arg Leu
    1               5                  10                  15

 cgc acg gcg aat cca ccg ggg tca gaa ttg ttc agg gat gtg gcc ata       96
 Arg Thr Ala Asn Pro Pro Gly Ser Glu Leu Phe Arg Asp Val Ala Ile
              20                  25                  30

 gtc ttc tcc caa gaa gaa tgg cag tgg ttg gca cct gct cag agg gat      144
 Val Phe Ser Gln Glu Glu Trp Gln Trp Leu Ala Pro Ala Gln Arg Asp
          35                  40                  45

 ttg tac aga gac gtg atg ttg gag acc tac agc aac ctg gtc tca ctg      192
 Leu Tyr Arg Asp Val Met Leu Glu Thr Tyr Ser Asn Leu Val Ser Leu
      50                  55                  60

 ggt ctt gcc gtt tcc aaa cct gat gtg atc tcc ttc cta gag caa ggc      240
 Gly Leu Ala Val Ser Lys Pro Asp Val Ile Ser Phe Leu Glu Gln Gly
  65                  70                  75                  80

 aaa gag ccc tgg atg gtg gag aga gtg gtg tct gga ggc ctg tgt cca      288
 Lys Glu Pro Trp Met Val Glu Arg Val Val Ser Gly Gly Leu Cys Pro
                  85                  90                  95

 gga aac tct atg aat gta agg aat gtg gga agg ctt tta atc aag gct      336
 Gly Asn Ser Met Asn Val Arg Asn Val Gly Arg Leu Leu Ile Lys Ala
             100                 105                 110

 caa ctc tta tac gac atc aga gaa ttc ata ccg gtg aga aac cct atg      384
 Gln Leu Leu Tyr Asp Ile Arg Glu Phe Ile Pro Val Arg Asn Pro Met
         115                 120                 125

 agt gca aag cat gaa tac aat gat atg atg act cct gtg acg act cct      432
 Ser Ala Lys His Glu Tyr Asn Asp Met Met Thr Pro Val Thr Thr Pro
     130                 135                 140

 aca tac ttc ttg ttc ctc att tac aga aag cca ata ggt att ttc cgg      480
 Thr Tyr Phe Leu Phe Leu Ile Tyr Arg Lys Pro Ile Gly Ile Phe Arg
 145                 150                 155                 160

 aat tcc aca gat gaa gcc tgt gac ttt aag ctg ccc aac gtc aaa ctg      528
 Asn Ser Thr Asp Glu Ala Cys Asp Phe Lys Leu Pro Asn Val Lys Leu
                 165                 170                 175

 gaa cct gtg atc cac aac act ctc ttt cac taa                          561
 Glu Pro Val Ile His Asn Thr Leu Phe His 
             180                 185





      <210> 958
      <211> 519
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(519)

      <400> 958
  atg gtg aaa att ttg ggg gtg gta tgg aga gtt aat ggg cga tgt ttc      48
  Met Val Lys Ile Leu Gly Val Val Trp Arg Val Asn Gly Arg Cys Phe
    1               5                  10                  15

 tca ggg ctg ctt cca gtg gga tta ggg gtg gcg tgg gaa cat aga gtg       96
 Ser Gly Leu Leu Pro Val Gly Leu Gly Val Ala Trp Glu His Arg Val
              20                  25                  30

 gga gag att aaa ctg aag gaa gat ttt gtg ggg ctt ctg agg cga tca      144
 Gly Glu Ile Lys Leu Lys Glu Asp Phe Val Gly Leu Leu Arg Arg Ser
          35                  40                  45

 ggc agc atc agt ctt cag ctg cta agc cga gaa gat ctg gga agt agt      192
 Gly Ser Ile Ser Leu Gln Leu Leu Ser Arg Glu Asp Leu Gly Ser Ser
      50                  55                  60

 cag aga gcc ttg ggc cag agt tca ggg gct ctg gga gtg gct gcc agg      240
 Gln Arg Ala Leu Gly Gln Ser Ser Gly Ala Leu Gly Val Ala Ala Arg
  65                  70                  75                  80

 tac cag cat gtt atg aag aat aag caa gaa gaa aga gaa gga gaa gaa      288
 Tyr Gln His Val Met Lys Asn Lys Gln Glu Glu Arg Glu Gly Glu Glu
                  85                  90                  95

 gca gga gga gga gga gag aag gaa agg gag gag gag gag gag aaa aag      336
 Ala Gly Gly Gly Gly Glu Lys Glu Arg Glu Glu Glu Glu Glu Lys Lys
             100                 105                 110

 atg gtg gta gag gag gag gag aag aag aag aag gag gag aag gag aag      384
 Met Val Val Glu Glu Glu Glu Lys Lys Lys Lys Glu Glu Lys Glu Lys
         115                 120                 125

 gag aag aag gag cag gag gag gag gaa gaa gaa gaa gag gag aag gga      432
 Glu Lys Lys Glu Gln Glu Glu Glu Glu Glu Glu Glu Glu Glu Lys Gly
     130                 135                 140

 act cac atg cag tct cag cag aaa gtt aca tgg cca aat gaa ttc gga      480
 Thr His Met Gln Ser Gln Gln Lys Val Thr Trp Pro Asn Glu Phe Gly
 145                 150                 155                 160

 gat tca aat cct gcc tcc tat ttg gag gaa tgt aag tga                  519
 Asp Ser Asn Pro Ala Ser Tyr Leu Glu Glu Cys Lys 
                 165                 170





      <210> 959
      <211> 249
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(249)

      <400> 959
  atg gca ggc aga gaa agt acc aga tta gag cca gtc ctg gct cta ctg      48
  Met Ala Gly Arg Glu Ser Thr Arg Leu Glu Pro Val Leu Ala Leu Leu
    1               5                  10                  15

 agt cta gtc tgt ggc act gtg ggc aaa ccc cgc aag ctc ctg gag cat       96
 Ser Leu Val Cys Gly Thr Val Gly Lys Pro Arg Lys Leu Leu Glu His
              20                  25                  30

 tct tca tct gta ttg gct gat aca gtc atc tct ccc tca ctg cac cag      144
 Ser Ser Ser Val Leu Ala Asp Thr Val Ile Ser Pro Ser Leu His Gln
          35                  40                  45

 ccc aaa gcc aag act gac cag aaa tcc aac acc ctt ctt ctt cct ggg      192
 Pro Lys Ala Lys Thr Asp Gln Lys Ser Asn Thr Leu Leu Leu Pro Gly
      50                  55                  60

 ccc ttc cac ccc caa cag gtg gct ggg tac gct tgt cct ggg aag gcc      240
 Pro Phe His Pro Gln Gln Val Ala Gly Tyr Ala Cys Pro Gly Lys Ala
  65                  70                  75                  80

 tta gca tga                                                          249
 Leu Ala 






      <210> 960
      <211> 1158
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1158)

      <400> 960
  atg gga gta aag ctg gga cta tgg tcc att gtg gtg ggc ctg gag act      48
  Met Gly Val Lys Leu Gly Leu Trp Ser Ile Val Val Gly Leu Glu Thr
    1               5                  10                  15

 ggg tct gtg gag gat ggc cta aaa cct gag tcc aca gaa aac agt cag       96
 Gly Ser Val Glu Asp Gly Leu Lys Pro Glu Ser Thr Glu Asn Ser Gln
              20                  25                  30

 gca gtg ggg tgg gct ttt ggt ctg agt tca tgg ggg tca tcc tgt act      144
 Ala Val Gly Trp Ala Phe Gly Leu Ser Ser Trp Gly Ser Ser Cys Thr
          35                  40                  45

 gga gtt ggt ctg gca ctt ggg tct gtg agg gca gtc ctg aaa cac aga      192
 Gly Val Gly Leu Ala Leu Gly Ser Val Arg Ala Val Leu Lys His Arg
      50                  55                  60

 tct gca tgg gca ggc cca aat cct cgg tct gaa ggg gcc aac ttg aca      240
 Ser Ala Trp Ala Gly Pro Asn Pro Arg Ser Glu Gly Ala Asn Leu Thr
  65                  70                  75                  80

 cta gag ttc act ggg gca agt gct gga gtc tac ttt gaa gac caa gtg      288
 Leu Glu Phe Thr Gly Ala Ser Ala Gly Val Tyr Phe Glu Asp Gln Val
                  85                  90                  95

 ctc act tca cta ttc tcc ctc ata tgg aag tta tct ctc cat gga atg      336
 Leu Thr Ser Leu Phe Ser Leu Ile Trp Lys Leu Ser Leu His Gly Met
             100                 105                 110

 cag tac agg ctt ggg aag ggg gtg ata tgg ctt ttc ctg tgc aac aaa      384
 Gln Tyr Arg Leu Gly Lys Gly Val Ile Trp Leu Phe Leu Cys Asn Lys
         115                 120                 125

 cca cca cca aat ctt agt ggt gtg gag caa caa cag ttt agg att tct      432
 Pro Pro Pro Asn Leu Ser Gly Val Glu Gln Gln Gln Phe Arg Ile Ser
     130                 135                 140

 cat gtt tct gtg agt gag ttg ggt gtt cct tct gcc agc tgt gcc tgg      480
 His Val Ser Val Ser Glu Leu Gly Val Pro Ser Ala Ser Cys Ala Trp
 145                 150                 155                 160

 gcc cat tca cat ggc tac atg ctg gtg ggg tat cag ttg gac tgg cag      528
 Ala His Ser His Gly Tyr Met Leu Val Gly Tyr Gln Leu Asp Trp Gln
                 165                 170                 175

 gtc cag ggc ggc tca ctc atg tat cag gca gct gtt gct ggc tgc cat      576
 Val Gln Gly Gly Ser Leu Met Tyr Gln Ala Ala Val Ala Gly Cys His
             180                 185                 190

 ctg agt tat cga aag gca att ggc aac tca atc caa aat aaa gaa tta      624
 Leu Ser Tyr Arg Lys Ala Ile Gly Asn Ser Ile Gln Asn Lys Glu Leu
         195                 200                 205

 aag tat ata gaa gcc tct cct aca aat ttc acc acc ata agt aac aaa      672
 Lys Tyr Ile Glu Ala Ser Pro Thr Asn Phe Thr Thr Ile Ser Asn Lys
     210                 215                 220

 ggt gag aga gag aaa gag aga aac aga gag gga aga gat att ttc tgc      720
 Gly Glu Arg Glu Lys Glu Arg Asn Arg Glu Gly Arg Asp Ile Phe Cys
 225                 230                 235                 240

 act tat tcc tct ttg ctt tta cag cgg aaa cct cca atg gtg gtg gac      768
 Thr Tyr Ser Ser Leu Leu Leu Gln Arg Lys Pro Pro Met Val Val Asp
                 245                 250                 255

 gat ctt ttt gaa gac atg aaa gat ggt gtt aaa ctg ctt gcc ctt ctg      816
 Asp Leu Phe Glu Asp Met Lys Asp Gly Val Lys Leu Leu Ala Leu Leu
             260                 265                 270

 gag gtc ctg tct ggg cag aaa ctg cct tgt gaa caa gga cgc cgg atg      864
 Glu Val Leu Ser Gly Gln Lys Leu Pro Cys Glu Gln Gly Arg Arg Met
         275                 280                 285

 aag cga atc cat gct gtg gct aac att ggc acg gca ctc aag ttc ctc      912
 Lys Arg Ile His Ala Val Ala Asn Ile Gly Thr Ala Leu Lys Phe Leu
     290                 295                 300

 gaa gga aga aag acc tta gtg att aaa gag ctc ttg ttt gtg gag gcc      960
 Glu Gly Arg Lys Thr Leu Val Ile Lys Glu Leu Leu Phe Val Glu Ala
 305                 310                 315                 320

 cat gtt act aac atg ctg cga aca tat cta ggt gct cta ctt aat gat     1008
 His Val Thr Asn Met Leu Arg Thr Tyr Leu Gly Ala Leu Leu Asn Asp
                 325                 330                 335

 ctc ata cga ttt tca caa ccc tta gca ttt ctg tac acc aac aac atc     1056
 Leu Ile Arg Phe Ser Gln Pro Leu Ala Phe Leu Tyr Thr Asn Asn Ile
             340                 345                 350

 tgg gct gag agt gaa ata aac aac aca atc cca ctc aca ata gcc aca     1104
 Trp Ala Glu Ser Glu Ile Asn Asn Thr Ile Pro Leu Thr Ile Ala Thr
         355                 360                 365

 aag aaa atg aaa tac cca gga atg cac cta ccc aaa gag gtt aaa gat     1152
 Lys Lys Met Lys Tyr Pro Gly Met His Leu Pro Lys Glu Val Lys Asp
     370                 375                 380

 ctc taa                                                             1158
 Leu 
 385





      <210> 961
      <211> 408
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(408)

      <400> 961
  atg ccc acg cgg gtc gcc ctg tgg ttc ttc atg cac atg cag atg cat      48
  Met Pro Thr Arg Val Ala Leu Trp Phe Phe Met His Met Gln Met His
    1               5                  10                  15

 atg gca atc cca gca atg acc ccc atg ata aat act att cca aaa aca       96
 Met Ala Ile Pro Ala Met Thr Pro Met Ile Asn Thr Ile Pro Lys Thr
              20                  25                  30

 atg ccc gca att gca gtg ccc cta aaa gga aaa aca aga tgc atg cca      144
 Met Pro Ala Ile Ala Val Pro Leu Lys Gly Lys Thr Arg Cys Met Pro
          35                  40                  45

 gca tcc ctg gtg tct ata cac cag ata cca gag gtg tcc cct ctg gct      192
 Ala Ser Leu Val Ser Ile His Gln Ile Pro Glu Val Ser Pro Leu Ala
      50                  55                  60

 gtg ata acc aaa gat atc tct aga ggt tgg gga tca cgt cca aat tgt      240
 Val Ile Thr Lys Asp Ile Ser Arg Gly Trp Gly Ser Arg Pro Asn Cys
  65                  70                  75                  80

 aaa gat gtt aag gaa gaa gta att aaa atg aga ttt gaa aga tca gtt      288
 Lys Asp Val Lys Glu Glu Val Ile Lys Met Arg Phe Glu Arg Ser Val
                  85                  90                  95

 agt caa gga aga aga gaa aag agt att caa gga gag gaa aca acc agt      336
 Ser Gln Gly Arg Arg Glu Lys Ser Ile Gln Gly Glu Glu Thr Thr Ser
             100                 105                 110

 agg aag gca aaa gag cac agg cct gtt tta aga gag aaa agt tca ata      384
 Arg Lys Ala Lys Glu His Arg Pro Val Leu Arg Glu Lys Ser Ser Ile
         115                 120                 125

 cag caa gtc tgt att cag ttt tga                                      408
 Gln Gln Val Cys Ile Gln Phe 
     130                 135





      <210> 962
      <211> 1182
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1182)

      <400> 962
  atg gcc ccc ctg tgt acc gtg gcg ctc tgc ctg cca gtc cag ctg ccc      48
  Met Ala Pro Leu Cys Thr Val Ala Leu Cys Leu Pro Val Gln Leu Pro
    1               5                  10                  15

 cag acg ggg cca agg cat cag gtc cac ggt gtc cca gtg cct tgg gga       96
 Gln Thr Gly Pro Arg His Gln Val His Gly Val Pro Val Pro Trp Gly
              20                  25                  30

 cac agc cgt tca aca gcc ggc cct gag ggg ctg aca gtc cag cag gaa      144
 His Ser Arg Ser Thr Ala Gly Pro Glu Gly Leu Thr Val Gln Gln Glu
          35                  40                  45

 gac aga gtt aat gaa atc aag acc tct gcc ccc tgg tgc cct cag gag      192
 Asp Arg Val Asn Glu Ile Lys Thr Ser Ala Pro Trp Cys Pro Gln Glu
      50                  55                  60

 gtg gcc cat ccc gac gct cac tct gaa cct ctc cca gat gtg gcc ttc      240
 Val Ala His Pro Asp Ala His Ser Glu Pro Leu Pro Asp Val Ala Phe
  65                  70                  75                  80

 ggt gcc tgc cgt ggg ccc tgg ttg gtg aat cct ggg aac cag ggc tct      288
 Gly Ala Cys Arg Gly Pro Trp Leu Val Asn Pro Gly Asn Gln Gly Ser
                  85                  90                  95

 gcc tcc cga ggg tct gac ttt gga gcc ggt gac ctt ggg cag gtc acc      336
 Ala Ser Arg Gly Ser Asp Phe Gly Ala Gly Asp Leu Gly Gln Val Thr
             100                 105                 110

 tca ccc cct gtt aaa tgg gct cca ggt cct cag ggg ccc cgc ggg gtt      384
 Ser Pro Pro Val Lys Trp Ala Pro Gly Pro Gln Gly Pro Arg Gly Val
         115                 120                 125

 tgc ctg cgt ggg aac caa gca cag gtg atc agc aag cga atc cgc acg      432
 Cys Leu Arg Gly Asn Gln Ala Gln Val Ile Ser Lys Arg Ile Arg Thr
     130                 135                 140

 cgg cgc gtc atc gtg gac aga ggg gcc ggc ttg ccc cgc ccc acg cag      480
 Arg Arg Val Ile Val Asp Arg Gly Ala Gly Leu Pro Arg Pro Thr Gln
 145                 150                 155                 160

 ctg acc cct ggc cac ccc gcc cca cac ccc tcc gat ccc tgg act cct      528
 Leu Thr Pro Gly His Pro Ala Pro His Pro Ser Asp Pro Trp Thr Pro
                 165                 170                 175

 tgg agg ccc ctc gcc cag ccc ccg gcc atc cct gag tgg tgg gtt ctg      576
 Trp Arg Pro Leu Ala Gln Pro Pro Ala Ile Pro Glu Trp Trp Val Leu
             180                 185                 190

 ccc ctg ggc gag tgg aac ggc cac ctt tat cag agc cag ccc tct ctg      624
 Pro Leu Gly Glu Trp Asn Gly His Leu Tyr Gln Ser Gln Pro Ser Leu
         195                 200                 205

 gca gtg tgt gat acc cat acc cag aag ggg cgg ccg cca cgg gaa atg      672
 Ala Val Cys Asp Thr His Thr Gln Lys Gly Arg Pro Pro Arg Glu Met
     210                 215                 220

 cca gcc acg ctc tta tct ggg agg ctt ggc cgg ctg gcc ctg gag ctc      720
 Pro Ala Thr Leu Leu Ser Gly Arg Leu Gly Arg Leu Ala Leu Glu Leu
 225                 230                 235                 240

 cga tta ggg agc agg acc gtt tgc ctg tgg gtg cct cgt ggg ccg gcc      768
 Arg Leu Gly Ser Arg Thr Val Cys Leu Trp Val Pro Arg Gly Pro Ala
                 245                 250                 255

 ctt gct ctg gag aac gac cat cgc agg gct cac agc tcg ctc aaa ccc      816
 Leu Ala Leu Glu Asn Asp His Arg Arg Ala His Ser Ser Leu Lys Pro
             260                 265                 270

 agc cac agg cat cct cct ggc tgc gtc cct aca ccc cac agt gcc cta      864
 Ser His Arg His Pro Pro Gly Cys Val Pro Thr Pro His Ser Ala Leu
         275                 280                 285

 gag atc ttg ctg cag ggc tgc cca ggc ccc tgg gac cca gca cct gcc      912
 Glu Ile Leu Leu Gln Gly Cys Pro Gly Pro Trp Asp Pro Ala Pro Ala
     290                 295                 300

 cgg ccc ctg cca ttc acc cca ggc ccc cag gac tgc cac cct cca ctg      960
 Arg Pro Leu Pro Phe Thr Pro Gly Pro Gln Asp Cys His Pro Pro Leu
 305                 310                 315                 320

 ccc ctt ggg cca acc cta gcg gga gac gag ctg gag ccg gtg gtg cag     1008
 Pro Leu Gly Pro Thr Leu Ala Gly Asp Glu Leu Glu Pro Val Val Gln
                 325                 330                 335

 gat ggg cag agg cgc ata cgg gcc cga ctc agc ctc gcc acg ggc ctg     1056
 Asp Gly Gln Arg Arg Ile Arg Ala Arg Leu Ser Leu Ala Thr Gly Leu
             340                 345                 350

 tcc tgg ggc ccg ttc cat ggg agt gtc cag acc aga gcc tca tcc ccc     1104
 Ser Trp Gly Pro Phe His Gly Ser Val Gln Thr Arg Ala Ser Ser Pro
         355                 360                 365

 agg cag gcg gag ccg ggc aac atg gac cca ggg gac agg ccc agc tta     1152
 Arg Gln Ala Glu Pro Gly Asn Met Asp Pro Gly Asp Arg Pro Ser Leu
     370                 375                 380

 gat gcc agc tcc ggg gct ctg gcc act tga                             1182
 Asp Ala Ser Ser Gly Ala Leu Ala Thr 
 385                 390





      <210> 963
      <211> 534
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(534)

      <400> 963
  atg gtg ggg cct gtg agc cgc ctg gtg ctc gga ccg ttg ttc act tct      48
  Met Val Gly Pro Val Ser Arg Leu Val Leu Gly Pro Leu Phe Thr Ser
    1               5                  10                  15

 ctg tgc atg gct ttg ctc tgc atg atg tca tta gca caa gga agc aac       96
 Leu Cys Met Ala Leu Leu Cys Met Met Ser Leu Ala Gln Gly Ser Asn
              20                  25                  30

 tca aaa atg ggc aac cag aag ggg cac tca ggc cat ctg tcc tta gcc      144
 Ser Lys Met Gly Asn Gln Lys Gly His Ser Gly His Leu Ser Leu Ala
          35                  40                  45

 aag acc ctt ggg tca gat tcc act ggt gtc ctt ggt tca ttt cac ttc      192
 Lys Thr Leu Gly Ser Asp Ser Thr Gly Val Leu Gly Ser Phe His Phe
      50                  55                  60

 tgt ggt cac aag aaa gcc aaa act gca cag tct tgt aac caa gta cat      240
 Cys Gly His Lys Lys Ala Lys Thr Ala Gln Ser Cys Asn Gln Val His
  65                  70                  75                  80

 ttc atg tac cta ctg ctg aaa cct aaa tca aat gtc cta ctg agt gac      288
 Phe Met Tyr Leu Leu Leu Lys Pro Lys Ser Asn Val Leu Leu Ser Asp
                  85                  90                  95

 ata cgg tca aaa cac agt gtt gaa gaa gtc caa gga agg gaa gag gaa      336
 Ile Arg Ser Lys His Ser Val Glu Glu Val Gln Gly Arg Glu Glu Glu
             100                 105                 110

 ttc agg cca cag cgt agg aaa agt ttt cag aaa agc aga gag atg tat      384
 Phe Arg Pro Gln Arg Arg Lys Ser Phe Gln Lys Ser Arg Glu Met Tyr
         115                 120                 125

 tta agc aaa ggg aca gca ttc agc cac aat ccc caa tgc tgt cca ggt      432
 Leu Ser Lys Gly Thr Ala Phe Ser His Asn Pro Gln Cys Cys Pro Gly
     130                 135                 140

 atg gag aaa gga tgc tgt ctc tgc ttt tgg ctg ctt tct agc cag atg      480
 Met Glu Lys Gly Cys Cys Leu Cys Phe Trp Leu Leu Ser Ser Gln Met
 145                 150                 155                 160

 gcc cat gat aaa gtg gaa gtc aag atg cca aag ttc ttc cta acc cag      528
 Ala His Asp Lys Val Glu Val Lys Met Pro Lys Phe Phe Leu Thr Gln
                 165                 170                 175

 cgt tga                                                              534
 Arg 






      <210> 964
      <211> 141
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(141)

      <400> 964
  atg gga ttt ttt atc tta tgc ttt gga ata ctc ttg gac agt aag ctg      48
  Met Gly Phe Phe Ile Leu Cys Phe Gly Ile Leu Leu Asp Ser Lys Leu
    1               5                  10                  15

 cga caa ctt ctg ttc aac aag ttg tct gcc tta agt tct tgg aag caa       96
 Arg Gln Leu Leu Phe Asn Lys Leu Ser Ala Leu Ser Ser Trp Lys Gln
              20                  25                  30

 aca gaa aag gta att atc tcc tac tgc cat gaa tcc aat aca tga          141
 Thr Glu Lys Val Ile Ile Ser Tyr Cys His Glu Ser Asn Thr 
          35                  40                  45





      <210> 965
      <211> 267
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(267)

      <400> 965
  atg ggt cat gac aat ctt ctc acg tca gtc agc cga ggc atc acc atc      48
  Met Gly His Asp Asn Leu Leu Thr Ser Val Ser Arg Gly Ile Thr Ile
    1               5                  10                  15

 ctg tcc tta atg gcc tta gca ggt gac agt gtt gca ggc ata ggg cca       96
 Leu Ser Leu Met Ala Leu Ala Gly Asp Ser Val Ala Gly Ile Gly Pro
              20                  25                  30

 ggg gcc aag aac caa gag cct gac ggt aca agc aac atg tac tcg gtg      144
 Gly Ala Lys Asn Gln Glu Pro Asp Gly Thr Ser Asn Met Tyr Ser Val
          35                  40                  45

 att cag gtg ggt aag gag aag tat gcc acc tca gtg tca gag gag gag      192
 Ile Gln Val Gly Lys Glu Lys Tyr Ala Thr Ser Val Ser Glu Glu Glu
      50                  55                  60

 gcc acc ttt gag gtg ctg ctg cta ctg tac ttg ggc ttc gcc gag gtg      240
 Ala Thr Phe Glu Val Leu Leu Leu Leu Tyr Leu Gly Phe Ala Glu Val
  65                  70                  75                  80

 tac ctg cag gac ctg cac cca gac tag                                  267
 Tyr Leu Gln Asp Leu His Pro Asp 
                  85





      <210> 966
      <211> 921
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(921)

      <400> 966
  atg gcc agg gga agt gtg cat gtg aag ctt act gtg atc aag cta ttt      48
  Met Ala Arg Gly Ser Val His Val Lys Leu Thr Val Ile Lys Leu Phe
    1               5                  10                  15

 gtt ttg ctc agc att gca aaa ggt gct gag gac ggc tac cac ctc gcc       96
 Val Leu Leu Ser Ile Ala Lys Gly Ala Glu Asp Gly Tyr His Leu Ala
              20                  25                  30

 cgg tgg gtc gct ctc ctt cac att ccc tcg gta cac ttc ctg cgc gaa      144
 Arg Trp Val Ala Leu Leu His Ile Pro Ser Val His Phe Leu Arg Glu
          35                  40                  45

 gac tgg tgc att gtc att tat atc tgt cac tct gac aga gac caa ggc      192
 Asp Trp Cys Ile Val Ile Tyr Ile Cys His Ser Asp Arg Asp Gln Gly
      50                  55                  60

 cgt gga gga aag aga gaa tgc ctc tcc aag ggg tat agt ggc tgc tac      240
 Arg Gly Gly Lys Arg Glu Cys Leu Ser Lys Gly Tyr Ser Gly Cys Tyr
  65                  70                  75                  80

 ttt aaa gtg gaa agc tgg gct ggt ttc acg gtc aag gcg ttt gtc aag      288
 Phe Lys Val Glu Ser Trp Ala Gly Phe Thr Val Lys Ala Phe Val Lys
                  85                  90                  95

 ctt aat agt gcc tgt ttc ctg ttc tat gac gaa tat gcc ccc ttt gtt      336
 Leu Asn Ser Ala Cys Phe Leu Phe Tyr Asp Glu Tyr Ala Pro Phe Val
             100                 105                 110

 att ttc tgg ccg ttc ccc att aac tgt gct gaa cca gac att ctg act      384
 Ile Phe Trp Pro Phe Pro Ile Asn Cys Ala Glu Pro Asp Ile Leu Thr
         115                 120                 125

 ggg caa aat cct cag ggt gtc cac tgt act ccc aat ggc tgt atc ttc      432
 Gly Gln Asn Pro Gln Gly Val His Cys Thr Pro Asn Gly Cys Ile Phe
     130                 135                 140

 tgc aat gct acg tat gtg ctt tgt gaa aag gca ggg ctg tac aag tta      480
 Cys Asn Ala Thr Tyr Val Leu Cys Glu Lys Ala Gly Leu Tyr Lys Leu
 145                 150                 155                 160

 gcc cca agt acc cta ata tgc acc tgt gca gtg ctg gtg aac aac cca      528
 Ala Pro Ser Thr Leu Ile Cys Thr Cys Ala Val Leu Val Asn Asn Pro
                 165                 170                 175

 tca gag aca gac aca ttg aga ctg tac aga ggc tcc atc cgc tgc ttc      576
 Ser Glu Thr Asp Thr Leu Arg Leu Tyr Arg Gly Ser Ile Arg Cys Phe
             180                 185                 190

 cga tgg ttg gac aat gtg ata act cca ctc ttg ctg tcc atc aga aag      624
 Arg Trp Leu Asp Asn Val Ile Thr Pro Leu Leu Leu Ser Ile Arg Lys
         195                 200                 205

 ctc gtc cgg tca ttc cca gat aaa atg cta tat tcc aac cgg gtt aat      672
 Leu Val Arg Ser Phe Pro Asp Lys Met Leu Tyr Ser Asn Arg Val Asn
     210                 215                 220

 ttc aaa gtg gcc ata gtc atc ctg cag gac ata ggt cac ttc tcc att      720
 Phe Lys Val Ala Ile Val Ile Leu Gln Asp Ile Gly His Phe Ser Ile
 225                 230                 235                 240

 tgg acc ttt atc ttt gtc aat ggc tgt cac ctg ata aat cag agt ccc      768
 Trp Thr Phe Ile Phe Val Asn Gly Cys His Leu Ile Asn Gln Ser Pro
                 245                 250                 255

 ggg ttc cgc atc cac ttg aac agc agc ata gta tgg gag gcc cac aaa      816
 Gly Phe Arg Ile His Leu Asn Ser Ser Ile Val Trp Glu Ala His Lys
             260                 265                 270

 gac tgg aga att gtc att tat gtc ttc aat gtt aac cct gac cac cac      864
 Asp Trp Arg Ile Val Ile Tyr Val Phe Asn Val Asn Pro Asp His His
         275                 280                 285

 tct ggc cac acg cag atg gtc cag ctc acg gct ggc ttc tac cac cag      912
 Ser Gly His Thr Gln Met Val Gln Leu Thr Ala Gly Phe Tyr His Gln
     290                 295                 300

 ctc ata taa                                                          921
 Leu Ile 
 305





      <210> 967
      <211> 297
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(297)

      <400> 967
  atg gtt cct tcc ctt gtc ctg cag cat cta atg tgt gct gga ctg tgg      48
  Met Val Pro Ser Leu Val Leu Gln His Leu Met Cys Ala Gly Leu Trp
    1               5                  10                  15

 tgc ctg gta gaa gga gac aca tcc tgc aag acc aag ctg gac cct ccc       96
 Cys Leu Val Glu Gly Asp Thr Ser Cys Lys Thr Lys Leu Asp Pro Pro
              20                  25                  30

 ctg gat ggc acc gag tgt ggg gca gac aag tgg tgc cgc gcg ggg gag      144
 Leu Asp Gly Thr Glu Cys Gly Ala Asp Lys Trp Cys Arg Ala Gly Glu
          35                  40                  45

 tgc gtg agc aag acg ccc atc ccg gag cat gtg gac gga gac tgg agc      192
 Cys Val Ser Lys Thr Pro Ile Pro Glu His Val Asp Gly Asp Trp Ser
      50                  55                  60

 ccg tgg ggc gcc tgg agc atg tgc agc cga aca tgt ggg acg gga gcc      240
 Pro Trp Gly Ala Trp Ser Met Cys Ser Arg Thr Cys Gly Thr Gly Ala
  65                  70                  75                  80

 cgc ttc agg cag agg aaa tgt gac aac ccc cca cac ttc aaa cag gac      288
 Arg Phe Arg Gln Arg Lys Cys Asp Asn Pro Pro His Phe Lys Gln Asp
                  85                  90                  95

 cct ttc taa                                                          297
 Pro Phe 






      <210> 968
      <211> 1284
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1284)

      <400> 968
  atg aat gcc ctc tct atc ctc atc ccc ctg gat cca ctt ctt gcc tgt      48
  Met Asn Ala Leu Ser Ile Leu Ile Pro Leu Asp Pro Leu Leu Ala Cys
    1               5                  10                  15

 ccg aac cct cag ccc caa act cca ctc ttc ctc ctt ctc cac ctg tta       96
 Pro Asn Pro Gln Pro Gln Thr Pro Leu Phe Leu Leu Leu His Leu Leu
              20                  25                  30

 ctc att caa aaa ctg ctt caa cca gtc aaa cca cct ctg cct ttc tcc      144
 Leu Ile Gln Lys Leu Leu Gln Pro Val Lys Pro Pro Leu Pro Phe Ser
          35                  40                  45

 tac tct ggg aag tgg cta ggg tcg aag cag ttc ctg cag gct gtg gct      192
 Tyr Ser Gly Lys Trp Leu Gly Ser Lys Gln Phe Leu Gln Ala Val Ala
      50                  55                  60

 gaa ggt ctg cag ctg ttg ccc gtt cgt gag ccc ttt gct gtg gag aaa      240
 Glu Gly Leu Gln Leu Leu Pro Val Arg Glu Pro Phe Ala Val Glu Lys
  65                  70                  75                  80

 ctt gga gac gaa gga cat gga ggc ggc cat ctc gcc tac cct ggt ggt      288
 Leu Gly Asp Glu Gly His Gly Gly Gly His Leu Ala Tyr Pro Gly Gly
                  85                  90                  95

 ggc tct ggg gta gaa ggg atg caa gga ggc aga ggt ggg gcg gcc cgg      336
 Gly Ser Gly Val Glu Gly Met Gln Gly Gly Arg Gly Gly Ala Ala Arg
             100                 105                 110

 gaa cgc cgg ggc tcg gct gcg ctg cct cag cag ctg agc agc ccc cag      384
 Glu Arg Arg Gly Ser Ala Ala Leu Pro Gln Gln Leu Ser Ser Pro Gln
         115                 120                 125

 ggc ttc ctc aca gag cag agg gct gac agg aag aaa ggg atc ctc cct      432
 Gly Phe Leu Thr Glu Gln Arg Ala Asp Arg Lys Lys Gly Ile Leu Pro
     130                 135                 140

 ctg aag gag agc aga agc cca gga gcc tgc cac tca gcg gac ctt gca      480
 Leu Lys Glu Ser Arg Ser Pro Gly Ala Cys His Ser Ala Asp Leu Ala
 145                 150                 155                 160

 ggt ggg cag gtt gct gta agg atc ttt ctg gcg ctc gag cag gat gcg      528
 Gly Gly Gln Val Ala Val Arg Ile Phe Leu Ala Leu Glu Gln Asp Ala
                 165                 170                 175

 gtc ggc agt gat ctc ctg ctc agg cct cct ctg gca gtc agc aca cac      576
 Val Gly Ser Asp Leu Leu Leu Arg Pro Pro Leu Ala Val Ser Thr His
             180                 185                 190

 att gcc cag ctg gac ttc ggc acc gct gct cag agc ctg gat ccg cac      624
 Ile Ala Gln Leu Asp Phe Gly Thr Ala Ala Gln Ser Leu Asp Pro His
         195                 200                 205

 cag ctg ggc ctc aac gca ggc ctc cgt tcc tgc agt acg gtc ttc caa      672
 Gln Leu Gly Leu Asn Ala Gly Leu Arg Ser Cys Ser Thr Val Phe Gln
     210                 215                 220

 tgc ggt ttt cat gct gag ctg cga ctg cag ctc aat ctc aag acc ccg      720
 Cys Gly Phe His Ala Glu Leu Arg Leu Gln Leu Asn Leu Lys Thr Pro
 225                 230                 235                 240

 gag ggt acg cca ccg gtc cgc gac tcg gac ttg tgc atc tgg agc tgc      768
 Glu Gly Thr Pro Pro Val Arg Asp Ser Asp Leu Cys Ile Trp Ser Cys
                 245                 250                 255

 tcc gtg tgg cca gcg acc tcc cag ctc aga tcc tca gtc tgg ctg gtg      816
 Ser Val Trp Pro Ala Thr Ser Gln Leu Arg Ser Ser Val Trp Leu Val
             260                 265                 270

 acc agg ctt cag cat ctt ggg cat ctg ctc agt tat gac cgc ata ctg      864
 Thr Arg Leu Gln His Leu Gly His Leu Leu Ser Tyr Asp Arg Ile Leu
         275                 280                 285

 gct tca cgt gtt gcc cgg gat ctt ggc aag acc aat gcc tgg agc aga      912
 Ala Ser Arg Val Ala Arg Asp Leu Gly Lys Thr Asn Ala Trp Ser Arg
     290                 295                 300

 atc cac ctc cac act gac ctg gcc acc cgc agc act gat ttc ctc gtt      960
 Ile His Leu His Thr Asp Leu Ala Thr Arg Ser Thr Asp Phe Leu Val
 305                 310                 315                 320

 gtg gtt ctt ctc cag gtg atc cag ctc ctc ctg cag gcc ttg gat gtg     1008
 Val Val Leu Leu Gln Val Ile Gln Leu Leu Leu Gln Ala Leu Asp Val
                 325                 330                 335

 cgt ctt cag gtc agc cct ggc cgg ggt agg aac caa gtg gtc gtg gat     1056
 Arg Leu Gln Val Ser Pro Gly Arg Gly Arg Asn Gln Val Val Val Asp
             340                 345                 350

 gtt ctg cgt ggt gat ctt ggt gcc cgt cag cag cct gtc gga cct gca     1104
 Val Leu Arg Gly Asp Leu Gly Ala Arg Gln Gln Pro Val Gly Pro Ala
         355                 360                 365

 gag gac gct ggc atc gcc gct gcc ata gcc cca gag gag gat gag ggc     1152
 Glu Asp Ala Gly Ile Ala Ala Ala Ile Ala Pro Glu Glu Asp Glu Gly
     370                 375                 380

 aca aag tgg gtg gag gac aca gac agg cta cgg ctt cgg agc ccc agt     1200
 Thr Lys Trp Val Glu Asp Thr Asp Arg Leu Arg Leu Arg Ser Pro Ser
 385                 390                 395                 400

 gga tgc tgg gct cta gga agg cgc ccc cga ctc caa agt gca cgg agc     1248
 Gly Cys Trp Ala Leu Gly Arg Arg Pro Arg Leu Gln Ser Ala Arg Ser
                 405                 410                 415

 cgc tgc cca gcc ccc aaa gga cta agt ggc caa tga                     1284
 Arg Cys Pro Ala Pro Lys Gly Leu Ser Gly Gln 
             420                 425





      <210> 969
      <211> 834
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(834)

      <400> 969
  atg ctg tcc tta tac ttt tta att aga ggt tcc ccc gtc acc gtc aca      48
  Met Leu Ser Leu Tyr Phe Leu Ile Arg Gly Ser Pro Val Thr Val Thr
    1               5                  10                  15

 ctc tac gtg cat cct cag gtt tcc cag tca ccg tca cac tct aca tgc       96
 Leu Tyr Val His Pro Gln Val Ser Gln Ser Pro Ser His Ser Thr Cys
              20                  25                  30

 atc ccc agg ttc ccc agt cac cgt cac act cta cat gca tcc cag gtt      144
 Ile Pro Arg Phe Pro Ser His Arg His Thr Leu His Ala Ser Gln Val
          35                  40                  45

 ccc cca gtc acc gtc aca ctc tat atg cat ccc cag ggt tct cca gtc      192
 Pro Pro Val Thr Val Thr Leu Tyr Met His Pro Gln Gly Ser Pro Val
      50                  55                  60

 acc gtc aca ctc tac atg cat ccc cag gtt tcc cca gtc acc gtc aca      240
 Thr Val Thr Leu Tyr Met His Pro Gln Val Ser Pro Val Thr Val Thr
  65                  70                  75                  80

 ctc tac atg cat ccc cag gtt ccc cag tca ccg tca cac tct acg tgc      288
 Leu Tyr Met His Pro Gln Val Pro Gln Ser Pro Ser His Ser Thr Cys
                  85                  90                  95

 atc ccc agg tcc ccc gtc acc gtc aca ctc tac gtg cct ccc cag gtt      336
 Ile Pro Arg Ser Pro Val Thr Val Thr Leu Tyr Val Pro Pro Gln Val
             100                 105                 110

 ccc ccg tca ccg cac act cta cgt gca tcc cca ggt ttc cca gtc acc      384
 Pro Pro Ser Pro His Thr Leu Arg Ala Ser Pro Gly Phe Pro Val Thr
         115                 120                 125

 gtc aca ctc tac atg cat ccc cag gtt ccc cca gtc acc atc aca ctc      432
 Val Thr Leu Tyr Met His Pro Gln Val Pro Pro Val Thr Ile Thr Leu
     130                 135                 140

 tac gtg cat ccc cag gtt tcc cag tca ccg tca cac tct aga tgc atc      480
 Tyr Val His Pro Gln Val Ser Gln Ser Pro Ser His Ser Arg Cys Ile
 145                 150                 155                 160

 ccc agg ttc ccc cgt cac cgt cac act cta cat gca tcc cca ggt tcc      528
 Pro Arg Phe Pro Arg His Arg His Thr Leu His Ala Ser Pro Gly Ser
                 165                 170                 175

 cca gtc acc gtc aca ctc tac atg cat ccc cag gtt ccc cca gtc acc      576
 Pro Val Thr Val Thr Leu Tyr Met His Pro Gln Val Pro Pro Val Thr
             180                 185                 190

 gtc aca ctc tac atg cat ccc cag gtg tat ggg ggt cac ggg aca gcc      624
 Val Thr Leu Tyr Met His Pro Gln Val Tyr Gly Gly His Gly Thr Ala
         195                 200                 205

 ctt cgt tca ctg gta gct ttc acc tgt tct tcc ttg tgt tgt caa tac      672
 Leu Arg Ser Leu Val Ala Phe Thr Cys Ser Ser Leu Cys Cys Gln Tyr
     210                 215                 220

 cag aag ctg caa aat gtc aac tac cag aag agg caa gag gct gca gaa      720
 Gln Lys Leu Gln Asn Val Asn Tyr Gln Lys Arg Gln Glu Ala Ala Glu
 225                 230                 235                 240

 caa acc cgg aaa gag ttg agt gag aag aag ccg tgc att gtg ttt cag      768
 Gln Thr Arg Lys Glu Leu Ser Glu Lys Lys Pro Cys Ile Val Phe Gln
                 245                 250                 255

 agc tat gga aga tca gag aag cag tac aga tgg gaa aca agt tgg gtc      816
 Ser Tyr Gly Arg Ser Glu Lys Gln Tyr Arg Trp Glu Thr Ser Trp Val
             260                 265                 270

 ttc tgg ttc ctg gag tga                                              834
 Phe Trp Phe Leu Glu 
         275





      <210> 970
      <211> 915
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(915)

      <400> 970
  atg ctg ccg ccg ccg cgg ccc gca gct gcc ttg gcg ctg cct gtg ctc      48
  Met Leu Pro Pro Pro Arg Pro Ala Ala Ala Leu Ala Leu Pro Val Leu
    1               5                  10                  15

 ctg cta ctg ctg gtg gtg ctg acg ccg ccc ccg acc ggc gca agg cca       96
 Leu Leu Leu Leu Val Val Leu Thr Pro Pro Pro Thr Gly Ala Arg Pro
              20                  25                  30

 tcc cca ggc cca gat tac ctg cgg cgc ggc tgg atg cgg ctg cta gcg      144
 Ser Pro Gly Pro Asp Tyr Leu Arg Arg Gly Trp Met Arg Leu Leu Ala
          35                  40                  45

 gag ggc gag ggc tgc gct ccc tgc cgg cca gaa gag tgc gcc gcg ccg      192
 Glu Gly Glu Gly Cys Ala Pro Cys Arg Pro Glu Glu Cys Ala Ala Pro
      50                  55                  60

 cgg ggc tgc ctg gcg ggc agg gtg cgc gac gcg tgc ggc tgc tgc tgg      240
 Arg Gly Cys Leu Ala Gly Arg Val Arg Asp Ala Cys Gly Cys Cys Trp
  65                  70                  75                  80

 gaa tgc gcc aac ctc gag ggc cag ctc tgc gac ctg gac ccc agt gct      288
 Glu Cys Ala Asn Leu Glu Gly Gln Leu Cys Asp Leu Asp Pro Ser Ala
                  85                  90                  95

 cac ttc tac ggg cac tgc ggc gag cag ctt gag tgc cgg ctg gac aca      336
 His Phe Tyr Gly His Cys Gly Glu Gln Leu Glu Cys Arg Leu Asp Thr
             100                 105                 110

 ggc ggc gac ctg agc cgc gga gag gtg ccg gaa cct ctg tgt gcc tgt      384
 Gly Gly Asp Leu Ser Arg Gly Glu Val Pro Glu Pro Leu Cys Ala Cys
         115                 120                 125

 cgt tcg cag agt ccg ctc tgc ggg tcc gac ggt cac acc tac tcc cag      432
 Arg Ser Gln Ser Pro Leu Cys Gly Ser Asp Gly His Thr Tyr Ser Gln
     130                 135                 140

 atc tgc cgc ctg cag gag gcg gcc cgc gct cgg ccc gat gcc aac ctc      480
 Ile Cys Arg Leu Gln Glu Ala Ala Arg Ala Arg Pro Asp Ala Asn Leu
 145                 150                 155                 160

 act gtg gca cac ccg ggg ccc tgc gaa tcg ggg ccc cag atc gtg tca      528
 Thr Val Ala His Pro Gly Pro Cys Glu Ser Gly Pro Gln Ile Val Ser
                 165                 170                 175

 cat cca tat gac act tgg aat gtg aca ggg cag gat gtg atc ttt ggc      576
 His Pro Tyr Asp Thr Trp Asn Val Thr Gly Gln Asp Val Ile Phe Gly
             180                 185                 190

 tgt gaa gtg ttt gcc tac ccc atg gcc tcc atc gag tgg agg aag gat      624
 Cys Glu Val Phe Ala Tyr Pro Met Ala Ser Ile Glu Trp Arg Lys Asp
         195                 200                 205

 ggc ttg gac atc cag ctg cca ggg gat gac ccc cac atc tct gtg cag      672
 Gly Leu Asp Ile Gln Leu Pro Gly Asp Asp Pro His Ile Ser Val Gln
     210                 215                 220

 ttt agg ggt gga ccc cag agg ttt gag gtg act ggc tgg ctg cag atc      720
 Phe Arg Gly Gly Pro Gln Arg Phe Glu Val Thr Gly Trp Leu Gln Ile
 225                 230                 235                 240

 cag gct gtg cgt ccc agt gat gag ggc act tac cgc tgc ctt gcc cgc      768
 Gln Ala Val Arg Pro Ser Asp Glu Gly Thr Tyr Arg Cys Leu Ala Arg
                 245                 250                 255

 aat gcc ctg ggt caa gtg gag gcc cct gct agc ttg aca gtg ctc aca      816
 Asn Ala Leu Gly Gln Val Glu Ala Pro Ala Ser Leu Thr Val Leu Thr
             260                 265                 270

 cct gac cag ctg aac tct aca ggc atc ccc cag ctg cga tca cta aac      864
 Pro Asp Gln Leu Asn Ser Thr Gly Ile Pro Gln Leu Arg Ser Leu Asn
         275                 280                 285

 ctg gtt cct gag gag gag gct gag agt gaa gag aat gac gat tac tac      912
 Leu Val Pro Glu Glu Glu Ala Glu Ser Glu Glu Asn Asp Asp Tyr Tyr
     290                 295                 300

 tag                                                                  915
 






      <210> 971
      <211> 759
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(759)

      <400> 971
  atg ccc agc ctg ata ctg ctg ttt cta cta tgt gct ttt att gct ggt      48
  Met Pro Ser Leu Ile Leu Leu Phe Leu Leu Cys Ala Phe Ile Ala Gly
    1               5                  10                  15

 aca tta cag gaa tat cag aag aga atg aaa aaa cta gat cag cag tac       96
 Thr Leu Gln Glu Tyr Gln Lys Arg Met Lys Lys Leu Asp Gln Gln Tyr
              20                  25                  30

 aaa gag agg ata cgg aat gca ggc tgc gga cca ctg ggc tgc ttt ccc      144
 Lys Glu Arg Ile Arg Asn Ala Gly Cys Gly Pro Leu Gly Cys Phe Pro
          35                  40                  45

 cca cct gcc gcc tgc ccc cct acc ctg ccc cag ccc gtg gga gaa ttg      192
 Pro Pro Ala Ala Cys Pro Pro Thr Leu Pro Gln Pro Val Gly Glu Leu
      50                  55                  60

 tct tcc acc gaa ctg gtc cct ggt gcc aaa aag act gaa caa gtg gaa      240
 Ser Ser Thr Glu Leu Val Pro Gly Ala Lys Lys Thr Glu Gln Val Glu
  65                  70                  75                  80

 cga aat tac att aaa gaa aag aag gca gca gtg aaa gaa ttt gaa gac      288
 Arg Asn Tyr Ile Lys Glu Lys Lys Ala Ala Val Lys Glu Phe Glu Asp
                  85                  90                  95

 aag aag gtt gag ctg aaa gag aac ctg att gct gag cta gaa gaa aag      336
 Lys Lys Val Glu Leu Lys Glu Asn Leu Ile Ala Glu Leu Glu Glu Lys
             100                 105                 110

 aag aaa atg att gaa aat gaa aag ctg aca atg gaa ctg act gga gac      384
 Lys Lys Met Ile Glu Asn Glu Lys Leu Thr Met Glu Leu Thr Gly Asp
         115                 120                 125

 act gag gat gct agt gaa act gac ctg gca aag cat gat gaa gaa gac      432
 Thr Glu Asp Ala Ser Glu Thr Asp Leu Ala Lys His Asp Glu Glu Asp
     130                 135                 140

 tat gta gaa atg aag gaa cag atg tat cag gac aaa ctg gct tct ctc      480
 Tyr Val Glu Met Lys Glu Gln Met Tyr Gln Asp Lys Leu Ala Ser Leu
 145                 150                 155                 160

 aag agg cag ttg caa caa ctg caa gaa ggt tgt gat ttt cta aag gtt      528
 Lys Arg Gln Leu Gln Gln Leu Gln Glu Gly Cys Asp Phe Leu Lys Val
                 165                 170                 175

 att tac agc ttc atc ttg agc ctt gca att cag tat agt ccg tgg acc      576
 Ile Tyr Ser Phe Ile Leu Ser Leu Ala Ile Gln Tyr Ser Pro Trp Thr
             180                 185                 190

 agc agc aat ggc att acc tgg aag ctt gtt agg aat gca gga tct ctg      624
 Ser Ser Asn Gly Ile Thr Trp Lys Leu Val Arg Asn Ala Gly Ser Leu
         195                 200                 205

 gtc tca gac cta ttg aaa cta gga atc tgc att tta aca aga tgc tca      672
 Val Ser Asp Leu Leu Lys Leu Gly Ile Cys Ile Leu Thr Arg Cys Ser
     210                 215                 220

 gcc aca gtg aca gtt gat gct cca gtt aga act cag gca atg gga gca      720
 Ala Thr Val Thr Val Asp Ala Pro Val Arg Thr Gln Ala Met Gly Ala
 225                 230                 235                 240

 gag ccc cgg cct cct aca gtg gac atg gag tgt gag tga                  759
 Glu Pro Arg Pro Pro Thr Val Asp Met Glu Cys Glu 
                 245                 250





      <210> 972
      <211> 468
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(468)

      <400> 972
  atg gag agt ggg gaa ggc ttt gtc gga gac aat tgc gca agt gtt ctc      48
  Met Glu Ser Gly Glu Gly Phe Val Gly Asp Asn Cys Ala Ser Val Leu
    1               5                  10                  15

 ctt ggc tgc aac tgg ctg cta ttc tgg ctg cag gca gcc atg tgt gca       96
 Leu Gly Cys Asn Trp Leu Leu Phe Trp Leu Gln Ala Ala Met Cys Ala
              20                  25                  30

 ttt gga gcc cag gaa gcc ttg ggg cag ccc tgc aac acc tca gat cat      144
 Phe Gly Ala Gln Glu Ala Leu Gly Gln Pro Cys Asn Thr Ser Asp His
          35                  40                  45

 gta gcc ctg aaa ggt gtg gct cag acc ctg ggg gct gtg gca gct gtg      192
 Val Ala Leu Lys Gly Val Ala Gln Thr Leu Gly Ala Val Ala Ala Val
      50                  55                  60

 gct gtg ctg ctg ggg cct gga gga ggc cag gga cat gta cac ggg tgc      240
 Ala Val Leu Leu Gly Pro Gly Gly Gly Gln Gly His Val His Gly Cys
  65                  70                  75                  80

 tca gca tct gca ggc cag ggc cac atc act ggc ctc act ggg gtg atg      288
 Ser Ala Ser Ala Gly Gln Gly His Ile Thr Gly Leu Thr Gly Val Met
                  85                  90                  95

 gag ttt cgg gag gac agt tcg aat ccc tat gtc cag ttt gaa atc ctt      336
 Glu Phe Arg Glu Asp Ser Ser Asn Pro Tyr Val Gln Phe Glu Ile Leu
             100                 105                 110

 ggc act acc tat agt gag act ttt ggc aaa gac atg cgc aag gtg tct      384
 Gly Thr Thr Tyr Ser Glu Thr Phe Gly Lys Asp Met Arg Lys Val Ser
         115                 120                 125

 gga cct tcc acg ttg cca agg caa tgc gcc tca aaa acc ctg aag cca      432
 Gly Pro Ser Thr Leu Pro Arg Gln Cys Ala Ser Lys Thr Leu Lys Pro
     130                 135                 140

 gtg gga gct ggc atc tct caa tat aag aag ctt tga                      468
 Val Gly Ala Gly Ile Ser Gln Tyr Lys Lys Leu 
 145                 150                 155





      <210> 973
      <211> 525
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(525)

      <400> 973
  atg gtg ctt att tgg aag acc ttc ttc atc ttc aga ata ttg atc caa      48
  Met Val Leu Ile Trp Lys Thr Phe Phe Ile Phe Arg Ile Leu Ile Gln
    1               5                  10                  15

 gtc ctt tgg ggc cac tgc tac tgt cag agt tgt ttt gag ttt ggc agt       96
 Val Leu Trp Gly His Cys Tyr Cys Gln Ser Cys Phe Glu Phe Gly Ser
              20                  25                  30

 acc tct cca gag cct caa gtg cgt atc ttc aaa tta ttt gct ctc tgg      144
 Thr Ser Pro Glu Pro Gln Val Arg Ile Phe Lys Leu Phe Ala Leu Trp
          35                  40                  45

 aaa gat gct gat aaa att ttg tcc act acc ata gta tcc ctg ctg gat      192
 Lys Asp Ala Asp Lys Ile Leu Ser Thr Thr Ile Val Ser Leu Leu Asp
      50                  55                  60

 ggg aac cat atc ttt aca ata gac tct cca ccc att ggc aag gtg ata      240
 Gly Asn His Ile Phe Thr Ile Asp Ser Pro Pro Ile Gly Lys Val Ile
  65                  70                  75                  80

 gct act caa tgt ctt gag aag ttg gtg gac cct gtc ctc cat cca aga      288
 Ala Thr Gln Cys Leu Glu Lys Leu Val Asp Pro Val Leu His Pro Arg
                  85                  90                  95

 agt gct gcc aag gaa acc agg gga cct agc aaa gag tca gga gaa aat      336
 Ser Ala Ala Lys Glu Thr Arg Gly Pro Ser Lys Glu Ser Gly Glu Asn
             100                 105                 110

 ggc caa agg aat tct gac att cca tac ctg aat gaa ctg ttt tcg ctc      384
 Gly Gln Arg Asn Ser Asp Ile Pro Tyr Leu Asn Glu Leu Phe Ser Leu
         115                 120                 125

 ttg gtt ctt ggc ccc tgg ccc tat gcc tgc aac act gtc acc tgc acg      432
 Leu Val Leu Gly Pro Trp Pro Tyr Ala Cys Asn Thr Val Thr Cys Thr
     130                 135                 140

 tgg att ggg aac cac ata gcc ccc gga cct gct aag gcc att aag gac      480
 Trp Ile Gly Asn His Ile Ala Pro Gly Pro Ala Lys Ala Ile Lys Asp
 145                 150                 155                 160

 agg atg gtg atg cct cgg ctg act gac gtg aga aga ttg tca tga          525
 Arg Met Val Met Pro Arg Leu Thr Asp Val Arg Arg Leu Ser 
                 165                 170





      <210> 974
      <211> 1284
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1284)

      <400> 974
  atg agc ctg gct gct gtc ctc ccc ctg ctc tgg ggc cgg tgg aag gtg      48
  Met Ser Leu Ala Ala Val Leu Pro Leu Leu Trp Gly Arg Trp Lys Val
    1               5                  10                  15

 gag ggc agc tca tgg ctc cct aat cta att cca cgg cag agc cca gaa       96
 Glu Gly Ser Ser Trp Leu Pro Asn Leu Ile Pro Arg Gln Ser Pro Glu
              20                  25                  30

 acg cct gct gac ctg ctt ccg ccg aga gca gca gag cct gtg acg ggg      144
 Thr Pro Ala Asp Leu Leu Pro Pro Arg Ala Ala Glu Pro Val Thr Gly
          35                  40                  45

 ccc ctg gtg ggg gcc tgg gtt ggc tct gtg ctg act gca tct gat ctg      192
 Pro Leu Val Gly Ala Trp Val Gly Ser Val Leu Thr Ala Ser Asp Leu
      50                  55                  60

 gct ggg gca gaa tgt ggg gac aaa cgt gcc ctg ggc atg ggg cca cct      240
 Ala Gly Ala Glu Cys Gly Asp Lys Arg Ala Leu Gly Met Gly Pro Pro
  65                  70                  75                  80

 cct ccg cca cag ctc ggt gac cgt gga gaa agg ccc ggc tgt cgt cag      288
 Pro Pro Pro Gln Leu Gly Asp Arg Gly Glu Arg Pro Gly Cys Arg Gln
                  85                  90                  95

 gcc atg tct ggt cca tgg ccc tcc ccc gac agc cgg acc aag gga acg      336
 Ala Met Ser Gly Pro Trp Pro Ser Pro Asp Ser Arg Thr Lys Gly Thr
             100                 105                 110

 gtg gcc tgg ctg gcg gag gta ctc ctc tgg gtt gga ggg agt gtg gtg      384
 Val Ala Trp Leu Ala Glu Val Leu Leu Trp Val Gly Gly Ser Val Val
         115                 120                 125

 ctg tct tca gag tgg cag ctc ggc ccc ctg gga gtg gcc gtg cct ccg      432
 Leu Ser Ser Glu Trp Gln Leu Gly Pro Leu Gly Val Ala Val Pro Pro
     130                 135                 140

 ctg acg gcc gtg tct ctc ctg cga gga gtg gct gtg cct ccg ctg aca      480
 Leu Thr Ala Val Ser Leu Leu Arg Gly Val Ala Val Pro Pro Leu Thr
 145                 150                 155                 160

 gcc gtg tct ctc ccg tgt cca gtg gag cgg tgc atg ggt gcc atg caa      528
 Ala Val Ser Leu Pro Cys Pro Val Glu Arg Cys Met Gly Ala Met Gln
                 165                 170                 175

 gag ggg atg cag atg gtg aag ctg cgt ggc ggc tcc aag ggc ctg gtc      576
 Glu Gly Met Gln Met Val Lys Leu Arg Gly Gly Ser Lys Gly Leu Val
             180                 185                 190

 cgc ttc tac tac ctg gac gag cac cgc tcc tgc atc cgc tgg agg ccc      624
 Arg Phe Tyr Tyr Leu Asp Glu His Arg Ser Cys Ile Arg Trp Arg Pro
         195                 200                 205

 tca cgc aag aac gag aag gcc aag atc tcc atc gac tcc atc cag gag      672
 Ser Arg Lys Asn Glu Lys Ala Lys Ile Ser Ile Asp Ser Ile Gln Glu
     210                 215                 220

 gtg agt gag ggg cgg cag tcg gag gtc ttc cag cgc tac cct gac ggc      720
 Val Ser Glu Gly Arg Gln Ser Glu Val Phe Gln Arg Tyr Pro Asp Gly
 225                 230                 235                 240

 agc ttc gac ccc aac tgc tgc ttc agc atc tac cac ggc agc cac cgc      768
 Ser Phe Asp Pro Asn Cys Cys Phe Ser Ile Tyr His Gly Ser His Arg
                 245                 250                 255

 gag tcg ctg gac ctg gtc tcc acc agc agc gag gtg gcg cgc acc tgg      816
 Glu Ser Leu Asp Leu Val Ser Thr Ser Ser Glu Val Ala Arg Thr Trp
             260                 265                 270

 gtc act ggc ctg cgc tac ctc atg gcc ggc atc agc gac gag gac agc      864
 Val Thr Gly Leu Arg Tyr Leu Met Ala Gly Ile Ser Asp Glu Asp Ser
         275                 280                 285

 ctg gct cgc cgc cag cgc acc agg gac caa tat cct tgg gca cct atc      912
 Leu Ala Arg Arg Gln Arg Thr Arg Asp Gln Tyr Pro Trp Ala Pro Ile
     290                 295                 300

 ggg caa tgc aga ccc agg gac cgg ccc ctt ggc tgc tca ccc tgg ggg      960
 Gly Gln Cys Arg Pro Arg Asp Arg Pro Leu Gly Cys Ser Pro Trp Gly
 305                 310                 315                 320

 ggc ctg tcc ttt gcc ggg tca cac act ggg gaa gtg gcc ggc cag agg     1008
 Gly Leu Ser Phe Ala Gly Ser His Thr Gly Glu Val Ala Gly Gln Arg
                 325                 330                 335

 gtg gag tgg ctg aag cag acg ttt gac gag gcc gac aag aac ggg gat     1056
 Val Glu Trp Leu Lys Gln Thr Phe Asp Glu Ala Asp Lys Asn Gly Asp
             340                 345                 350

 ggc agc ctg agc att ggc gag gtc ctg cag ctg ctg cac aag ctc aac     1104
 Gly Ser Leu Ser Ile Gly Glu Val Leu Gln Leu Leu His Lys Leu Asn
         355                 360                 365

 gtg aac ctg ccc cgg cag agg gtg aag cag atg ttc agg gcc cca gcc     1152
 Val Asn Leu Pro Arg Gln Arg Val Lys Gln Met Phe Arg Ala Pro Ala
     370                 375                 380

 ccg cag cct cga ggg ggg tac acc agc cct ggc agg gcc cag tct gat     1200
 Pro Gln Pro Arg Gly Gly Tyr Thr Ser Pro Gly Arg Ala Gln Ser Asp
 385                 390                 395                 400

 gcg cag cag ctc gtt act ttc ccc atg ccg ccc tcg ccc aac cac cct     1248
 Ala Gln Gln Leu Val Thr Phe Pro Met Pro Pro Ser Pro Asn His Pro
                 405                 410                 415

 gat gtt agg agt tat gaa aat gca gcc ttc agc tga                     1284
 Asp Val Arg Ser Tyr Glu Asn Ala Ala Phe Ser 
             420                 425





      <210> 975
      <211> 345
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(345)

      <400> 975
  atg gct aat acc aca gtt ctc aag gct tgg att ctg tcc tta ccc tac      48
  Met Ala Asn Thr Thr Val Leu Lys Ala Trp Ile Leu Ser Leu Pro Tyr
    1               5                  10                  15

 atc ttc agg agg ctg cca gtc tgt gcg ctg gtc tgt ccg tcc gtc cga       96
 Ile Phe Arg Arg Leu Pro Val Cys Ala Leu Val Cys Pro Ser Val Arg
              20                  25                  30

 atc cct ccg tcc cac cag caa tgc agc gtc cct ctt ccg gtc ttc tgt      144
 Ile Pro Pro Ser His Gln Gln Cys Ser Val Pro Leu Pro Val Phe Cys
          35                  40                  45

 gcc cac agt cct ctc cca ctc tgt gcc cct ggc cgc ttc gct cgg acc      192
 Ala His Ser Pro Leu Pro Leu Cys Ala Pro Gly Arg Phe Ala Arg Thr
      50                  55                  60

 tgc ttc aac aca aag cgt ttg cag tct cct atg gaa ccc aca aaa gat      240
 Cys Phe Asn Thr Lys Arg Leu Gln Ser Pro Met Glu Pro Thr Lys Asp
  65                  70                  75                  80

 gtt ttt aat ttt tca aaa cct agc cta gaa ctg aaa gca gga gca tta      288
 Val Phe Asn Phe Ser Lys Pro Ser Leu Glu Leu Lys Ala Gly Ala Leu
                  85                  90                  95

 gaa gca tat gtg ggg aaa aca gag gta aat gtt atc cct ctg aaa cac      336
 Glu Ala Tyr Val Gly Lys Thr Glu Val Asn Val Ile Pro Leu Lys His
             100                 105                 110

 aag aag tga                                                          345
 Lys Lys 






      <210> 976
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 976
  atg gag tgc tta cca gta cac atg tgg ctg gac tgc ttg ttt cag atg      48
  Met Glu Cys Leu Pro Val His Met Trp Leu Asp Cys Leu Phe Gln Met
    1               5                  10                  15

 ttt cag atc ctg cct ctg cta ctt gga gca tct ctc cac tgt ggt ttg       96
 Phe Gln Ile Leu Pro Leu Leu Leu Gly Ala Ser Leu His Cys Gly Leu
              20                  25                  30

 aat cca cgg ggt att gat cac cct gcc cat gct gaa ggt att aaa ctg      144
 Asn Pro Arg Gly Ile Asp His Pro Ala His Ala Glu Gly Ile Lys Leu
          35                  40                  45

 caa att gaa ggt gaa ggt gtg gaa tct caa tcc att aaa aat aaa aat      192
 Gln Ile Glu Gly Glu Gly Val Glu Ser Gln Ser Ile Lys Asn Lys Asn
      50                  55                  60

 ttc cag aag gtg cct gac cag aaa gga act ccc aag cga ctg cag gca      240
 Phe Gln Lys Val Pro Asp Gln Lys Gly Thr Pro Lys Arg Leu Gln Ala
  65                  70                  75                  80

 gaa gct gag acg gct aag gat att tac tgg ctg atg atc aat gaa gtt      288
 Glu Ala Glu Thr Ala Lys Asp Ile Tyr Trp Leu Met Ile Asn Glu Val
                  85                  90                  95

 tgg ttt gtg aac aac att gga aat gag tga                              318
 Trp Phe Val Asn Asn Ile Gly Asn Glu 
             100                 105





      <210> 977
      <211> 1317
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1317)

      <400> 977
  atg atc gct gta gaa tat cta ctg cgt gca ctg ctc ttt agc tgt ggt      48
  Met Ile Ala Val Glu Tyr Leu Leu Arg Ala Leu Leu Phe Ser Cys Gly
    1               5                  10                  15

 tta tgc aca ttg ctt agc agc act ctt gcg ctg gag aag aag atg gcc       96
 Leu Cys Thr Leu Leu Ser Ser Thr Leu Ala Leu Glu Lys Lys Met Ala
              20                  25                  30

 ggc agg caa ggc cga gag gag ctc atc aag aag ggg ctg ctg gag atg      144
 Gly Arg Gln Gly Arg Glu Glu Leu Ile Lys Lys Gly Leu Leu Glu Met
          35                  40                  45

 atg gag cag gat gct gaa agc aaa act tgc aac ccc gat gga gga ccc      192
 Met Glu Gln Asp Ala Glu Ser Lys Thr Cys Asn Pro Asp Gly Gly Pro
      50                  55                  60

 cga tct gta cag agt gaa cca ccc act ccc aag tcg gag acg ctg act      240
 Arg Ser Val Gln Ser Glu Pro Pro Thr Pro Lys Ser Glu Thr Leu Thr
  65                  70                  75                  80

 tca gaa gat gcc cag ccc gga agc ccc ttg gcc act ggg acg gac cag      288
 Ser Glu Asp Ala Gln Pro Gly Ser Pro Leu Ala Thr Gly Thr Asp Gln
                  85                  90                  95

 gtc tcc ctg gac aag cca ctg tcc tca gct gcc cac ttg gac gat gca      336
 Val Ser Leu Asp Lys Pro Leu Ser Ser Ala Ala His Leu Asp Asp Ala
             100                 105                 110

 gca ccc aag gga act gcc cac atc tgg gcc cag tcg ctc tgt gtt gtg      384
 Ala Pro Lys Gly Thr Ala His Ile Trp Ala Gln Ser Leu Cys Val Val
         115                 120                 125

 ggt aat tcc atg aca gac aga tgt cat cta atg gca gac aaa gcc aga      432
 Gly Asn Ser Met Thr Asp Arg Cys His Leu Met Ala Asp Lys Ala Arg
     130                 135                 140

 tcc tca agt ggc aaa tgt gtc acc tgg tgg ctg ccc tta acc act gcc      480
 Ser Ser Ser Gly Lys Cys Val Thr Trp Trp Leu Pro Leu Thr Thr Ala
 145                 150                 155                 160

 tgg ggc cta tgc tgg tcc cag cta ccc ctg ggg cct ggg ctc tgg gca      528
 Trp Gly Leu Cys Trp Ser Gln Leu Pro Leu Gly Pro Gly Leu Trp Ala
                 165                 170                 175

 act gct ggg cac cga gtg gag gaa cct cat ctg gga gtt gcc aag atg      576
 Thr Ala Gly His Arg Val Glu Glu Pro His Leu Gly Val Ala Lys Met
             180                 185                 190

 cct tct gca tcc agt ggt gaa gaa gca gac gct ggc agc ctc ctg ccc      624
 Pro Ser Ala Ser Ser Gly Glu Glu Ala Asp Ala Gly Ser Leu Leu Pro
         195                 200                 205

 acc acc aat gag ctc tcc caa gcc tta gct ggg gct gac tcc ctg gac      672
 Thr Thr Asn Glu Leu Ser Gln Ala Leu Ala Gly Ala Asp Ser Leu Asp
     210                 215                 220

 agt cct ccc aga cct ctg gag aga tcc gtg ggc cag ctc ccc agc ccc      720
 Ser Pro Pro Arg Pro Leu Glu Arg Ser Val Gly Gln Leu Pro Ser Pro
 225                 230                 235                 240

 cca ctg ctg ccc act ccg cca ccc aag gca agc tcc aaa acc aca aaa      768
 Pro Leu Leu Pro Thr Pro Pro Pro Lys Ala Ser Ser Lys Thr Thr Lys
                 245                 250                 255

 aat gtc aca ggc caa gcc aca ctc ttc caa gcc tcc agc atg aag agt      816
 Asn Val Thr Gly Gln Ala Thr Leu Phe Gln Ala Ser Ser Met Lys Ser
             260                 265                 270

 gcc gac cct tcc ctc cgg ggc cag ctc tcc aca ccc acg ggg tct ccg      864
 Ala Asp Pro Ser Leu Arg Gly Gln Leu Ser Thr Pro Thr Gly Ser Pro
         275                 280                 285

 cat ctc acc acg gtc cac cgg cct ctt ccc cca agc cgc gtc att gag      912
 His Leu Thr Thr Val His Arg Pro Leu Pro Pro Ser Arg Val Ile Glu
     290                 295                 300

 gag ctg cac agg gcg ctg gcc acg aag cac cgc cag gac agt ttt caa      960
 Glu Leu His Arg Ala Leu Ala Thr Lys His Arg Gln Asp Ser Phe Gln
 305                 310                 315                 320

 gga aga gaa agt aaa ggg tct cca aag aag cgg ctg gat gtc cgt ctg     1008
 Gly Arg Glu Ser Lys Gly Ser Pro Lys Lys Arg Leu Asp Val Arg Leu
                 325                 330                 335

 tcg aga acg tcc agc gtg gag cgg ggc aag gag agg gag gag gct tgg     1056
 Ser Arg Thr Ser Ser Val Glu Arg Gly Lys Glu Arg Glu Glu Ala Trp
             340                 345                 350

 agc ttt gac ggg gca ttg gag aac aag cga act gcc gct aag gaa tct     1104
 Ser Phe Asp Gly Ala Leu Glu Asn Lys Arg Thr Ala Ala Lys Glu Ser
         355                 360                 365

 gag gag aac aag gag aac ctg atc ata aat tct gaa ctc aaa gac gac     1152
 Glu Glu Asn Lys Glu Asn Leu Ile Ile Asn Ser Glu Leu Lys Asp Asp
     370                 375                 380

 ttg ctt ttg tat cag gac gag gag gcg ctg aac gac tcc att att tct     1200
 Leu Leu Leu Tyr Gln Asp Glu Glu Ala Leu Asn Asp Ser Ile Ile Ser
 385                 390                 395                 400

 gga cac aat gct ttc att ggt gaa gag gga gat ggg aac tgc ttc ctc     1248
 Gly His Asn Ala Phe Ile Gly Glu Glu Gly Asp Gly Asn Cys Phe Leu
                 405                 410                 415

 ttg aca ttg aca atg tca gca gcc agg gcc cct tac tgg gtg ttt ctt     1296
 Leu Thr Leu Thr Met Ser Ala Ala Arg Ala Pro Tyr Trp Val Phe Leu
             420                 425                 430

 gtg tcc ggg atg ctg gtc taa                                         1317
 Val Ser Gly Met Leu Val 
         435





      <210> 978
      <211> 924
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(924)

      <400> 978
  atg cag tgg gtc ctg cct gct ttg cta ccc cct tca ttc tgt tca cgc      48
  Met Gln Trp Val Leu Pro Ala Leu Leu Pro Pro Ser Phe Cys Ser Arg
    1               5                  10                  15

 atg tta gct gtg ggc tac ccc aac tcc act ccc cag cct tac agc cat       96
 Met Leu Ala Val Gly Tyr Pro Asn Ser Thr Pro Gln Pro Tyr Ser His
              20                  25                  30

 gcc ctg ggc ctc cac atg tcc aag agg gtc ttc aga cta gcc cat ctg      144
 Ala Leu Gly Leu His Met Ser Lys Arg Val Phe Arg Leu Ala His Leu
          35                  40                  45

 cct tct atc att aaa gga cac ggc aac gcg acc ctc gcc aaa tgc tgt      192
 Pro Ser Ile Ile Lys Gly His Gly Asn Ala Thr Leu Ala Lys Cys Cys
      50                  55                  60

 tgc ctg gat ctt gga ctc cct ggc ctc cgt aat ggc tct gag aac cgc      240
 Cys Leu Asp Leu Gly Leu Pro Gly Leu Arg Asn Gly Ser Glu Asn Arg
  65                  70                  75                  80

 tgg gga agt ctg tac agc tcc agt cat ccc aat act gtg aag ggc ctc      288
 Trp Gly Ser Leu Tyr Ser Ser Ser His Pro Asn Thr Val Lys Gly Leu
                  85                  90                  95

 acc cct gtt cat ctc gac act gtg aag ggc ctc acc cct gtt cat ccc      336
 Thr Pro Val His Leu Asp Thr Val Lys Gly Leu Thr Pro Val His Pro
             100                 105                 110

 gac gct gtg aag ggc ctc acc cct gtt cct ccc gac gct gtg aag ggc      384
 Asp Ala Val Lys Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly
         115                 120                 125

 ctc acc cct gtt cct ccc gac gct gtg aag ggc ctc acc cct gtt cct      432
 Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val Pro
     130                 135                 140

 ccc gac gct gtg aag ggc ctc acc cct gtt cct ccc gac gct gtg aag      480
 Pro Asp Ala Val Lys Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys
 145                 150                 155                 160

 ggc ctc acc cct gtt cct ccc gac gct gtg aag ggc ctc acc cct gtt      528
 Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val
                 165                 170                 175

 cct ccc gac gct gtg aag ggc ctc acc cct gtt cat ccc gac gct gtg      576
 Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val His Pro Asp Ala Val
             180                 185                 190

 aag ggc ctc acc cct gtt cct cct ggt ggg caa ctg ctg tac gtc agg      624
 Lys Gly Leu Thr Pro Val Pro Pro Gly Gly Gln Leu Leu Tyr Val Arg
         195                 200                 205

 cat tct gcc agg tgc aga aac aga gct gag ctc gtg gcc ggg tcc tgt      672
 His Ser Ala Arg Cys Arg Asn Arg Ala Glu Leu Val Ala Gly Ser Cys
     210                 215                 220

 ggt tgc tcc tgg agg aaa ggg ggc ctg aat att gga tgg aaa aag tct      720
 Gly Cys Ser Trp Arg Lys Gly Gly Leu Asn Ile Gly Trp Lys Lys Ser
 225                 230                 235                 240

 tat gag gag cct gga aaa gaa cct gtc aag ttc aac tgt gag cac cag      768
 Tyr Glu Glu Pro Gly Lys Glu Pro Val Lys Phe Asn Cys Glu His Gln
                 245                 250                 255

 agc ctg ggc agg cag aga gac aag atg ggg cag ctg gca gag gag cag      816
 Ser Leu Gly Arg Gln Arg Asp Lys Met Gly Gln Leu Ala Glu Glu Gln
             260                 265                 270

 cat ctc tgc cct tgg cag tgt gag cat ctg tct gtc agc agc tgc ctc      864
 His Leu Cys Pro Trp Gln Cys Glu His Leu Ser Val Ser Ser Cys Leu
         275                 280                 285

 tgg tgg aag cct gca ggc agc ttg tac ctc ctg gca gtg gga gga gac      912
 Trp Trp Lys Pro Ala Gly Ser Leu Tyr Leu Leu Ala Val Gly Gly Asp
     290                 295                 300

 acc cag cac taa                                                      924
 Thr Gln His 
 305





      <210> 979
      <211> 666
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(666)

      <400> 979
  atg gca gca tgg gtt ggg gag ggg ctg ttg cca cta ctg ggc atg ggg      48
  Met Ala Ala Trp Val Gly Glu Gly Leu Leu Pro Leu Leu Gly Met Gly
    1               5                  10                  15

 atg ctt ttc ctt ctg gca aaa aag ttt cat caa agt tta caa act cag       96
 Met Leu Phe Leu Leu Ala Lys Lys Phe His Gln Ser Leu Gln Thr Gln
              20                  25                  30

 tgt ccc cat ctt caa aag cat cct tcc aca tgt tcc cat tcc aag ttg      144
 Cys Pro His Leu Gln Lys His Pro Ser Thr Cys Ser His Ser Lys Leu
          35                  40                  45

 cag gat ccc att ctt ttt cca atc aat gcc cct cac ttt aat ggg aaa      192
 Gln Asp Pro Ile Leu Phe Pro Ile Asn Ala Pro His Phe Asn Gly Lys
      50                  55                  60

 cac ctg gaa agg ctg cac atg ccc ttt ttt gga gaa gta aac ttt cta      240
 His Leu Glu Arg Leu His Met Pro Phe Phe Gly Glu Val Asn Phe Leu
  65                  70                  75                  80

 ggg gtc cag ttg tgt ggg atc ttt caa gac att cct tct aag gtg aag      288
 Gly Val Gln Leu Cys Gly Ile Phe Gln Asp Ile Pro Ser Lys Val Lys
                  85                  90                  95

 gat aag ttg ctg aat ttg acc cca cct aca acc aag aaa gag gca caa      336
 Asp Lys Leu Leu Asn Leu Thr Pro Pro Thr Thr Lys Lys Glu Ala Gln
             100                 105                 110

 tgc cta gtg ggc cta ttt gga ttt tgc agg caa gac att cct cat atg      384
 Cys Leu Val Gly Leu Phe Gly Phe Cys Arg Gln Asp Ile Pro His Met
         115                 120                 125

 ggt gtg tta ctg tgg cct att cat cga gtt acc caa aag gct gcc agt      432
 Gly Val Leu Leu Trp Pro Ile His Arg Val Thr Gln Lys Ala Ala Ser
     130                 135                 140

 ttt gag tgg gct cca gaa cag gag aag gct ctg caa cag atc aag gat      480
 Phe Glu Trp Ala Pro Glu Gln Glu Lys Ala Leu Gln Gln Ile Lys Asp
 145                 150                 155                 160

 gct gtg caa gct gct ctg cca ctt ggg cca tat gac cca gca aat tca      528
 Ala Val Gln Ala Ala Leu Pro Leu Gly Pro Tyr Asp Pro Ala Asn Ser
                 165                 170                 175

 ata gtg ctt gag gtg aca gcg gca gat aag gat gct gat cag agc ctc      576
 Ile Val Leu Glu Val Thr Ala Ala Asp Lys Asp Ala Asp Gln Ser Leu
             180                 185                 190

 tgg caa gcc ccc ata ggt gaa tta cag cag agg cct cta aaa ttt tgg      624
 Trp Gln Ala Pro Ile Gly Glu Leu Gln Gln Arg Pro Leu Lys Phe Trp
         195                 200                 205

 agc agg ccc tgc cat ctt ctg aaa aaa cta ctc tcc ttt tga              666
 Ser Arg Pro Cys His Leu Leu Lys Lys Leu Leu Ser Phe 
     210                 215                 220





      <210> 980
      <211> 396
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(396)

      <400> 980
  atg gtg atc acc act atc ata gct atc att aaa tta ctc att gtg act      48
  Met Val Ile Thr Thr Ile Ile Ala Ile Ile Lys Leu Leu Ile Val Thr
    1               5                  10                  15

 ggt tgt ccc act ttc ctt agg ttt tct tct gcc atc tgt gac agc ttc       96
 Gly Cys Pro Thr Phe Leu Arg Phe Ser Ser Ala Ile Cys Asp Ser Phe
              20                  25                  30

 ttg atc tgt ccc cag cgt cag tct caa cat ggc tgc aac cag ggg atc      144
 Leu Ile Cys Pro Gln Arg Gln Ser Gln His Gly Cys Asn Gln Gly Ile
          35                  40                  45

 ctc ggg atc ctc cca gaa tct att cct cag cat cag gct cat gat aag      192
 Leu Gly Ile Leu Pro Glu Ser Ile Pro Gln His Gln Ala His Asp Lys
      50                  55                  60

 gtt tca ggt gcc tcg atg ata tcc aaa ttg gca gtt gat ttg gtc ctg      240
 Val Ser Gly Ala Ser Met Ile Ser Lys Leu Ala Val Asp Leu Val Leu
  65                  70                  75                  80

 gag aaa cac aag gat aac ctc tac ccc aag tta tta ttc tac cca ttt      288
 Glu Lys His Lys Asp Asn Leu Tyr Pro Lys Leu Leu Phe Tyr Pro Phe
                  85                  90                  95

 ccc aac ttt tta tca ttg gct ctc tcc acc aaa cca gtt gtt ctg ctt      336
 Pro Asn Phe Leu Ser Leu Ala Leu Ser Thr Lys Pro Val Val Leu Leu
             100                 105                 110

 ctg tct ttg cag ctg gtt tct gta gat gct att cag ctg ctg ata gca      384
 Leu Ser Leu Gln Leu Val Ser Val Asp Ala Ile Gln Leu Leu Ile Ala
         115                 120                 125

 tct ggc ctt tag                                                      396
 Ser Gly Leu 
     130





      <210> 981
      <211> 1491
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1491)

      <400> 981
  atg gct gca gct tgg acc gtg gtg ctg gtg act ttg gtg cta ggc ttg      48
  Met Ala Ala Ala Trp Thr Val Val Leu Val Thr Leu Val Leu Gly Leu
    1               5                  10                  15

 gcc gtg gca ggc cct gtc ccc act tcc aag ccc acc aca act ggg aag       96
 Ala Val Ala Gly Pro Val Pro Thr Ser Lys Pro Thr Thr Thr Gly Lys
              20                  25                  30

 ggc tgc cac att ggc agg ttc aaa tct ctg tca cca cag gag cta gcg      144
 Gly Cys His Ile Gly Arg Phe Lys Ser Leu Ser Pro Gln Glu Leu Ala
          35                  40                  45

 agc ttc aag aag gcc agg gac gcc ttg gtg agg gag cgc cct gtg gcc      192
 Ser Phe Lys Lys Ala Arg Asp Ala Leu Val Arg Glu Arg Pro Val Ala
      50                  55                  60

 ttg gag gct gag ctg gcc ctg acg ctg aag gtc ctg gag gcc gct gct      240
 Leu Glu Ala Glu Leu Ala Leu Thr Leu Lys Val Leu Glu Ala Ala Ala
  65                  70                  75                  80

 ggc cca gcc ctg gag gac gtc cta gac cag ccc ctt cac acc ctg cac      288
 Gly Pro Ala Leu Glu Asp Val Leu Asp Gln Pro Leu His Thr Leu His
                  85                  90                  95

 cac atc ctc tcc cag ctc cag gcc tgt atc cag cct cag ccc aca gca      336
 His Ile Leu Ser Gln Leu Gln Ala Cys Ile Gln Pro Gln Pro Thr Ala
             100                 105                 110

 ggg ccc agg ccc cgg ggc cgc ctc cac cac tgg ctg cac cgg ctc cag      384
 Gly Pro Arg Pro Arg Gly Arg Leu His His Trp Leu His Arg Leu Gln
         115                 120                 125

 gag gcc ccc aaa aag cgc ctc gta gtg gtc ctg ggc cgg cag ggc cgg      432
 Glu Ala Pro Lys Lys Arg Leu Val Val Val Leu Gly Arg Gln Gly Arg
     130                 135                 140

 ggc ctg tgc cgc gcc tgt gcc tgc gcc gtt ggt ctg cga gca cac gtg      480
 Gly Leu Cys Arg Ala Cys Ala Cys Ala Val Gly Leu Arg Ala His Val
 145                 150                 155                 160

 gct gac ccg cgg gag cga cct gga gcc ctt gac gcg gcg gct gtc ccc      528
 Ala Asp Pro Arg Glu Arg Pro Gly Ala Leu Asp Ala Ala Ala Val Pro
                 165                 170                 175

 gtc gcc ata cac ctt ata gcg gat cat gag cag aac gat gaa gac gag      576
 Val Ala Ile His Leu Ile Ala Asp His Glu Gln Asn Asp Glu Asp Glu
             180                 185                 190

 gac cga ggc gac gat gac gcc ccc gat ggc gat gat cat ggt gcc gcc      624
 Asp Arg Gly Asp Asp Asp Ala Pro Asp Gly Asp Asp His Gly Ala Ala
         195                 200                 205

 caa gaa atg ggc cct cag cgg gcg gca ggg cgc cgg atc ccc agc ggt      672
 Gln Glu Met Gly Pro Gln Arg Ala Ala Gly Arg Arg Ile Pro Ser Gly
     210                 215                 220

 ggt gaa ctg tac aca gcc cac cac tcg cgt tgc cgg cag cgc tgt ggc      720
 Gly Glu Leu Tyr Thr Ala His His Ser Arg Cys Arg Gln Arg Cys Gly
 225                 230                 235                 240

 ccc gtc gtc gta gac cgc cag cac gca caa gtc gta ggc acg gcc cgc      768
 Pro Val Val Val Asp Arg Gln His Ala Gln Val Val Gly Thr Ala Arg
                 245                 250                 255

 cgc cag gtc att cac cag gaa ggt ctg act gat att aaa ggc aac cac      816
 Arg Gln Val Ile His Gln Glu Gly Leu Thr Asp Ile Lys Gly Asn His
             260                 265                 270

 ctc ata tgt tca tgt gcc acc aga agt cac caa atc acg cta cca ggc      864
 Leu Ile Cys Ser Cys Ala Thr Arg Ser His Gln Ile Thr Leu Pro Gly
         275                 280                 285

 ctc tgg gct ggc cag cgg atg agc acg gag ttc gag gtg agc tcg gct      912
 Leu Trp Ala Gly Gln Arg Met Ser Thr Glu Phe Glu Val Ser Ser Ala
     290                 295                 300

 gcc acg agc cga cgc tca gcc gca gaa tcg ttg gca cct ggt ctg ccc      960
 Ala Thr Ser Arg Arg Ser Ala Ala Glu Ser Leu Ala Pro Gly Leu Pro
 305                 310                 315                 320

 ggc gtg gcg atg tca gag gag ccg ggc tcg gaa gag ccc gtc ggg cgg     1008
 Gly Val Ala Met Ser Glu Glu Pro Gly Ser Glu Glu Pro Val Gly Arg
                 325                 330                 335

 gag ttt atg cag gcg gtt gga ggt cat gtc cag acg gac cag ctt gtg     1056
 Glu Phe Met Gln Ala Val Gly Gly His Val Gln Thr Asp Gln Leu Val
             340                 345                 350

 aag ctg cac gaa ggt ccc ctc cgc gat gtg gtc gat gag gtt gtg gtc     1104
 Lys Leu His Glu Gly Pro Leu Arg Asp Val Val Asp Glu Val Val Val
         355                 360                 365

 cag cga cag atc cag gtc ctc cac ggt gga cag gaa ggc gtc aaa ggc     1152
 Gln Arg Gln Ile Gln Val Leu His Gly Gly Gln Glu Gly Val Lys Gly
     370                 375                 380

 cgc cga ctc cac ccg gcg gat ctg gtt gtt tcc aag gat cag gtg gcg     1200
 Arg Arg Leu His Pro Ala Asp Leu Val Val Ser Lys Asp Gln Val Ala
 385                 390                 395                 400

 gag gtt gcc cag gcc gcg gag ctg gtc gcc gcg cac ctc cgc cag gcg     1248
 Glu Val Ala Gln Ala Ala Glu Leu Val Ala Ala His Leu Arg Gln Ala
                 405                 410                 415

 gtt gct gtc cag gtg cag ggc ccg gag ggc acg cag gtc ggc gaa ggc     1296
 Val Ala Val Gln Val Gln Gly Pro Glu Gly Thr Gln Val Gly Glu Gly
             420                 425                 430

 gcc agc tgc cac ctg gcc gat ggt gtt ccg gga gag agt gag gtg cac     1344
 Ala Ser Cys His Leu Ala Asp Gly Val Pro Gly Glu Ser Glu Val His
         435                 440                 445

 cag gct ggt cat gtt ggc gaa gtc tcg gcg gcg cac ggc ggc gat gaa     1392
 Gln Ala Gly His Val Gly Glu Val Ser Ala Ala His Gly Gly Asp Glu
     450                 455                 460

 gtt gtc ggc ata gaa cag tgc cct att att gag agt aag tac ttt gaa     1440
 Val Val Gly Ile Glu Gln Cys Pro Ile Ile Glu Ser Lys Tyr Phe Glu
 465                 470                 475                 480

 atc aaa cag act cag gtt caa atc ctg att ccc ctt ttg cta gct ctg     1488
 Ile Lys Gln Thr Gln Val Gln Ile Leu Ile Pro Leu Leu Leu Ala Leu
                 485                 490                 495

 tga                                                                 1491
 






      <210> 982
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 982
  atg aca tca ctg atg atg cta atg ctg acc atc tgc agg tat att cca      48
  Met Thr Ser Leu Met Met Leu Met Leu Thr Ile Cys Arg Tyr Ile Pro
    1               5                  10                  15

 gat gct ggg gat tgg gaa gtg gac ttc ttt ggg gaa ggc att gtt ctg       96
 Asp Ala Gly Asp Trp Glu Val Asp Phe Phe Gly Glu Gly Ile Val Leu
              20                  25                  30

 cct acc atg gta ccc aat ggc ttt atc tct atg aat cag agt gtc ctg      144
 Pro Thr Met Val Pro Asn Gly Phe Ile Ser Met Asn Gln Ser Val Leu
          35                  40                  45

 gtt gag aag atg tgt tac tcg ctt gac atc aag ttg aag aaa ttc atc      192
 Val Glu Lys Met Cys Tyr Ser Leu Asp Ile Lys Leu Lys Lys Phe Ile
      50                  55                  60

 agt ttt gta aac ttc agt aaa gtg ctg atg aat aaa gtc atc tgc agt      240
 Ser Phe Val Asn Phe Ser Lys Val Leu Met Asn Lys Val Ile Cys Ser
  65                  70                  75                  80

 tgc ttt caa ttc agg aca atc tag                                      264
 Cys Phe Gln Phe Arg Thr Ile 
                  85





      <210> 983
      <211> 543
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(543)

      <400> 983
  atg aag ctg gga acc agg ccc cta ctc aac ccc ctg agc aga gct gcc      48
  Met Lys Leu Gly Thr Arg Pro Leu Leu Asn Pro Leu Ser Arg Ala Ala
    1               5                  10                  15

 ctg ctt tgg cct cag ggc cag agc ctg gtg cta aac cca ccc tgg cac       96
 Leu Leu Trp Pro Gln Gly Gln Ser Leu Val Leu Asn Pro Pro Trp His
              20                  25                  30

 cca gtg ggc ctc agc aga aca ctg tcc ccc gac tct gca tcg tcc ctc      144
 Pro Val Gly Leu Ser Arg Thr Leu Ser Pro Asp Ser Ala Ser Ser Leu
          35                  40                  45

 agc cct gga tgt gcc cca tgc tcc acc ctg ccc ctc gag tgt ccg agc      192
 Ser Pro Gly Cys Ala Pro Cys Ser Thr Leu Pro Leu Glu Cys Pro Ser
      50                  55                  60

 aga gaa gcc ttc ctg cgg aaa ccc ggc tct cct gaa gtc caa cca ctc      240
 Arg Glu Ala Phe Leu Arg Lys Pro Gly Ser Pro Glu Val Gln Pro Leu
  65                  70                  75                  80

 agg ttc ctc gca ccc tgc cct tgt tct ggc cca gct gtg ctg gtg cag      288
 Arg Phe Leu Ala Pro Cys Pro Cys Ser Gly Pro Ala Val Leu Val Gln
                  85                  90                  95

 gcc tgg agg aaa acg gac gcc agg ttt ggt gtg gaa ggg gag ctc gga      336
 Ala Trp Arg Lys Thr Asp Ala Arg Phe Gly Val Glu Gly Glu Leu Gly
             100                 105                 110

 ggc gat gaa ggc cca ggc agg tgg aag gtg gtg gtt gag gac cgg gga      384
 Gly Asp Glu Gly Pro Gly Arg Trp Lys Val Val Val Glu Asp Arg Gly
         115                 120                 125

 gca ggg cgc tgg ctg ggg aga ggc aga gtg aag aag ccg agg gcg gcc      432
 Ala Gly Arg Trp Leu Gly Arg Gly Arg Val Lys Lys Pro Arg Ala Ala
     130                 135                 140

 ctg ctc gca gca gcg cga gga gcc acg ggg tgc tgc cct cct ccg cag      480
 Leu Leu Ala Ala Ala Arg Gly Ala Thr Gly Cys Cys Pro Pro Pro Gln
 145                 150                 155                 160

 ccc gag gcc cac ttc aca cgc act gag ccc aag cgc gag tct ctg ccc      528
 Pro Glu Ala His Phe Thr Arg Thr Glu Pro Lys Arg Glu Ser Leu Pro
                 165                 170                 175

 gtc agc cgc gtc tga                                                  543
 Val Ser Arg Val 
             180





      <210> 984
      <211> 1065
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1065)

      <400> 984
  atg aag agt tcc tca ttc acg tgt ttg gtg ctt gat gct ggc tgg ctg      48
  Met Lys Ser Ser Ser Phe Thr Cys Leu Val Leu Asp Ala Gly Trp Leu
    1               5                  10                  15

 ctg caa ggc agc act ggg ttc cat ggg gac cta ata cct atc att gct       96
 Leu Gln Gly Ser Thr Gly Phe His Gly Asp Leu Ile Pro Ile Ile Ala
              20                  25                  30

 gct ctg gaa tat aat cag tgg ttc aca aaa ctg tcc tct aag gat cta      144
 Ala Leu Glu Tyr Asn Gln Trp Phe Thr Lys Leu Ser Ser Lys Asp Leu
          35                  40                  45

 aaa ctg agt tat gga ata gtc aaa gaa tgt ttt ctg tta cag tcc act      192
 Lys Leu Ser Tyr Gly Ile Val Lys Glu Cys Phe Leu Leu Gln Ser Thr
      50                  55                  60

 gat gtc tgt gaa cag atc ttg agg gtg gtg agt agg tcc aat cga ctg      240
 Asp Val Cys Glu Gln Ile Leu Arg Val Val Ser Arg Ser Asn Arg Leu
  65                  70                  75                  80

 gaa gaa ttg gtg ttg gaa aat gct gga ctt aga aca aaa cag tct atg      288
 Glu Glu Leu Val Leu Glu Asn Ala Gly Leu Arg Thr Lys Gln Ser Met
                  85                  90                  95

 ctc att gca gtc ctt gga tgg gtg agc tgg tgt tcc caa tct ccc act      336
 Leu Ile Ala Val Leu Gly Trp Val Ser Trp Cys Ser Gln Ser Pro Thr
             100                 105                 110

 ctg gtt att aaa ttt aga aga tat ctg att tta aat acc ata aat tcc      384
 Leu Val Ile Lys Phe Arg Arg Tyr Leu Ile Leu Asn Thr Ile Asn Ser
         115                 120                 125

 tgg aaa gga aaa gaa gta cct cca tct ttc aag caa ttt ttt agt agt      432
 Trp Lys Gly Lys Glu Val Pro Pro Ser Phe Lys Gln Phe Phe Ser Ser
     130                 135                 140

 tct ctg gct ttg atg cac atc aac ctt tca ggc aca aaa ctg tct cct      480
 Ser Leu Ala Leu Met His Ile Asn Leu Ser Gly Thr Lys Leu Ser Pro
 145                 150                 155                 160

 gag ccc tta aaa gca ctg tta ttg ggc ctg gct tgt aat cat aac ttg      528
 Glu Pro Leu Lys Ala Leu Leu Leu Gly Leu Ala Cys Asn His Asn Leu
                 165                 170                 175

 aaa ggg gtt tct ctg gat ctc agc aac tgt gag ctg aga tca gga ggt      576
 Lys Gly Val Ser Leu Asp Leu Ser Asn Cys Glu Leu Arg Ser Gly Gly
             180                 185                 190

 gct caa gta tta gaa ggt tgc att gct gaa ata cac aac atc acc agc      624
 Ala Gln Val Leu Glu Gly Cys Ile Ala Glu Ile His Asn Ile Thr Ser
         195                 200                 205

 tta gac atc tct gac aat gat acc atg caa gac aaa caa aac ctg cct      672
 Leu Asp Ile Ser Asp Asn Asp Thr Met Gln Asp Lys Gln Asn Leu Pro
     210                 215                 220

 tta ggc tgc gtg gct ttc aat atc tgg ttt aaa tgg atg gaa aat gag      720
 Leu Gly Cys Val Ala Phe Asn Ile Trp Phe Lys Trp Met Glu Asn Glu
 225                 230                 235                 240

 tgg act ggt ttg gat tca cca tac agc tta tgg tca aat aaa aac gtc      768
 Trp Thr Gly Leu Asp Ser Pro Tyr Ser Leu Trp Ser Asn Lys Asn Val
                 245                 250                 255

 aca caa ggc ctg cct ctg cag tcc ttg tcc ctg gct gac tcg aaa ctc      816
 Thr Gln Gly Leu Pro Leu Gln Ser Leu Ser Leu Ala Asp Ser Lys Leu
             260                 265                 270

 aag act gag gtc acc atc atc atc aat gcc ctg gga agc aac acc tcc      864
 Lys Thr Glu Val Thr Ile Ile Ile Asn Ala Leu Gly Ser Asn Thr Ser
         275                 280                 285

 ctg acc aaa gtg gac att agc ggc aac gga atg ggg gac atg gga gcg      912
 Leu Thr Lys Val Asp Ile Ser Gly Asn Gly Met Gly Asp Met Gly Ala
     290                 295                 300

 aag atg ctg gcc aaa gca ctg cag atc aac act aag ctc agg aac tac      960
 Lys Met Leu Ala Lys Ala Leu Gln Ile Asn Thr Lys Leu Arg Asn Tyr
 305                 310                 315                 320

 aca tta aga ttt atg cca att cct atg tat gat gct tct caa gcc cta     1008
 Thr Leu Arg Phe Met Pro Ile Pro Met Tyr Asp Ala Ser Gln Ala Leu
                 325                 330                 335

 aaa aca aac cct gaa aaa aca gaa gac gct ctg caa aag gta tta aag     1056
 Lys Thr Asn Pro Glu Lys Thr Glu Asp Ala Leu Gln Lys Val Leu Lys
             340                 345                 350

 aat cag tag                                                         1065
 Asn Gln 






      <210> 985
      <211> 180
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(180)

      <400> 985
  atg gtg gtg gcc act ccc aag atg gca gca agc ctt ttg ttc tct gac      48
  Met Val Val Ala Thr Pro Lys Met Ala Ala Ser Leu Leu Phe Ser Asp
    1               5                  10                  15

 ctg ggg ttc ttg gcc tca cgg att cca aag aat gga acc ttg ggc cat       96
 Leu Gly Phe Leu Ala Ser Arg Ile Pro Lys Asn Gly Thr Leu Gly His
              20                  25                  30

 gtg gtc agt gtt ata gct cta gta gaa gtc atg ggt cac gga aga gaa      144
 Val Val Ser Val Ile Ala Leu Val Glu Val Met Gly His Gly Arg Glu
          35                  40                  45

 ctg tgg aac cca gtg act agt gtt cag ctc gat tag                      180
 Leu Trp Asn Pro Val Thr Ser Val Gln Leu Asp 
      50                  55





      <210> 986
      <211> 666
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(666)

      <400> 986
  atg gat acc agc acc tgc tct ggt gga agt ggg agg gga gta aag tgg      48
  Met Asp Thr Ser Thr Cys Ser Gly Gly Ser Gly Arg Gly Val Lys Trp
    1               5                  10                  15

 act ctg cgg gag tcc ttg gtt tta gtt ttg ttt agt gca ctg gtt ttc       96
 Thr Leu Arg Glu Ser Leu Val Leu Val Leu Phe Ser Ala Leu Val Phe
              20                  25                  30

 tca aat gct ggt tat gct agc tgt gaa gct gtc aca cag aca gac tca      144
 Ser Asn Ala Gly Tyr Ala Ser Cys Glu Ala Val Thr Gln Thr Asp Ser
          35                  40                  45

 cga cct ctg gtt agc cag ggt gtt gca gga ttt tca ggt tcc cag tgg      192
 Arg Pro Leu Val Ser Gln Gly Val Ala Gly Phe Ser Gly Ser Gln Trp
      50                  55                  60

 gat gtg ggt gca gag gca gac ttc tcc tcc tct cac acc ttg gga act      240
 Asp Val Gly Ala Glu Ala Asp Phe Ser Ser Ser His Thr Leu Gly Thr
  65                  70                  75                  80

 cac gta gag ttt gca gcg gta agc tgc ttc ttt caa agg gtc tgt gaa      288
 His Val Glu Phe Ala Ala Val Ser Cys Phe Phe Gln Arg Val Cys Glu
                  85                  90                  95

 ttc ttt cag ttt tcc tgg tat gtt cct gtg gtg gtt ctt gga gca aaa      336
 Phe Phe Gln Phe Ser Trp Tyr Val Pro Val Val Val Leu Gly Ala Lys
             100                 105                 110

 ctt cac aat cta gaa gag aaa ggc gag gaa tgg cac tgc ctt ctg aaa      384
 Leu His Asn Leu Glu Glu Lys Gly Glu Glu Trp His Cys Leu Leu Lys
         115                 120                 125

 gat gac tgg ctt cta ctt cct tct ctt gtc cag ttc atg aac tcc ctg      432
 Asp Asp Trp Leu Leu Leu Pro Ser Leu Val Gln Phe Met Asn Ser Leu
     130                 135                 140

 gag ttt tgc aat gca gtc ata cag gtg gct cac ccc ttg att cga aat      480
 Glu Phe Cys Asn Ala Val Ile Gln Val Ala His Pro Leu Ile Arg Asn
 145                 150                 155                 160

 cag ctt gtc aat tac att tac aat gga ttt ttg gta cca gtc ttg gct      528
 Gln Leu Val Asn Tyr Ile Tyr Asn Gly Phe Leu Val Pro Val Leu Ala
                 165                 170                 175

 cct gct ctc cat aag tgg caa ctt gga act gtc aag atg ttc tcc aag      576
 Pro Ala Leu His Lys Trp Gln Leu Gly Thr Val Lys Met Phe Ser Lys
             180                 185                 190

 gct gag tct gtc ata gag aat gca agg tct gct gtg ggc atg gag agg      624
 Ala Glu Ser Val Ile Glu Asn Ala Arg Ser Ala Val Gly Met Glu Arg
         195                 200                 205

 agc agt ggt agc aca agt gcc ata gat ttg cca tct act taa              666
 Ser Ser Gly Ser Thr Ser Ala Ile Asp Leu Pro Ser Thr 
     210                 215                 220





      <210> 987
      <211> 441
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(441)

      <400> 987
  atg tcc aaa gtg atc atc ttc agc tac ctc ttc tgg ttt gtg ctc acc      48
  Met Ser Lys Val Ile Ile Phe Ser Tyr Leu Phe Trp Phe Val Leu Thr
    1               5                  10                  15

 atc atc ttc atc act ggg acc acc agg atc agc atc ttt tgc atg ggg       96
 Ile Ile Phe Ile Thr Gly Thr Thr Arg Ile Ser Ile Phe Cys Met Gly
              20                  25                  30

 tac ctg gtg gcc tgt ttc tac ttc ctg ctc ttt ggg ggc gat ttg ctg      144
 Tyr Leu Val Ala Cys Phe Tyr Phe Leu Leu Phe Gly Gly Asp Leu Leu
          35                  40                  45

 ttg aaa ccc atc aag agc atc ctg cgc tac tgg gac tgg ctg atc gca      192
 Leu Lys Pro Ile Lys Ser Ile Leu Arg Tyr Trp Asp Trp Leu Ile Ala
      50                  55                  60

 tac aac gtt ttt gtg att acg atg aaa aat atc ctg tca ata gga gca      240
 Tyr Asn Val Phe Val Ile Thr Met Lys Asn Ile Leu Ser Ile Gly Ala
  65                  70                  75                  80

 tgt gga tac att gga aca ttg gtg cac aat agt tgt tgg ttg atc cag      288
 Cys Gly Tyr Ile Gly Thr Leu Val His Asn Ser Cys Trp Leu Ile Gln
                  85                  90                  95

 gct ttc agc ctg gcc tgc aca gtc aaa ggc tat caa atg cgt aag tat      336
 Ala Phe Ser Leu Ala Cys Thr Val Lys Gly Tyr Gln Met Arg Lys Tyr
             100                 105                 110

 gaa aag caa gta gga gct gaa ctt ttc cag gcc aca att gta aaa gct      384
 Glu Lys Gln Val Gly Ala Glu Leu Phe Gln Ala Thr Ile Val Lys Ala
         115                 120                 125

 gta aag gca aga att gag gaa gag aag aag tcc atg gac cag ctg aag      432
 Val Lys Ala Arg Ile Glu Glu Glu Lys Lys Ser Met Asp Gln Leu Lys
     130                 135                 140

 cga cag taa                                                          441
 Arg Gln 
 145





      <210> 988
      <211> 432
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(432)

      <400> 988
  atg gtc aag ttc tgc tgg cag cac aaa ttt ggt cta acc tgg tcc ctc      48
  Met Val Lys Phe Cys Trp Gln His Lys Phe Gly Leu Thr Trp Ser Leu
    1               5                  10                  15

 atc agt ttg gat ctt gca gcc att gtt cgt cta cct gct gtt tac atc       96
 Ile Ser Leu Asp Leu Ala Ala Ile Val Arg Leu Pro Ala Val Tyr Ile
              20                  25                  30

 ctt gtg gcc gct acc agt gct tta ctt tgc ctg gtt gtt cct gga ctg      144
 Leu Val Ala Ala Thr Ser Ala Leu Leu Cys Leu Val Val Pro Gly Leu
          35                  40                  45

 gaa gac ccc aga gcg agg tgg cag gcg ttc ggc ctg ggt aag gaa ctg      192
 Glu Asp Pro Arg Ala Arg Trp Gln Ala Phe Gly Leu Gly Lys Glu Leu
      50                  55                  60

 gca gga gat ctg gca gtt cta gct gtc cca gat cct acc ttg ttg tcc      240
 Ala Gly Asp Leu Ala Val Leu Ala Val Pro Asp Pro Thr Leu Leu Ser
  65                  70                  75                  80

 aat ggc cac aga gac caa tat ctc agc cct cct gaa acc cat tca gga      288
 Asn Gly His Arg Asp Gln Tyr Leu Ser Pro Pro Glu Thr His Ser Gly
                  85                  90                  95

 aat ctg ttg gaa agc tct gct tta gag agc acc ctg atc cct gaa gta      336
 Asn Leu Leu Glu Ser Ser Ala Leu Glu Ser Thr Leu Ile Pro Glu Val
             100                 105                 110

 tca cca ccc ttg ttt ctg cca tgt aat ctc att cca cca cct ctg gca      384
 Ser Pro Pro Leu Phe Leu Pro Cys Asn Leu Ile Pro Pro Pro Leu Ala
         115                 120                 125

 ttt ctc tcc atg gct gca gat cct gaa gac aaa gga cct atc acc tga      432
 Phe Leu Ser Met Ala Ala Asp Pro Glu Asp Lys Gly Pro Ile Thr 
     130                 135                 140





      <210> 989
      <211> 648
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(648)

      <400> 989
  atg ata gcc tac aca tta ccc act ctt gcc ccc ttc tct ctg aca cgg      48
  Met Ile Ala Tyr Thr Leu Pro Thr Leu Ala Pro Phe Ser Leu Thr Arg
    1               5                  10                  15

 gcc tac act ctt acc ctt cag cag ctg aca ttg tcc atg agc aca gtg       96
 Ala Tyr Thr Leu Thr Leu Gln Gln Leu Thr Leu Ser Met Ser Thr Val
              20                  25                  30

 gtg cag act tct ggg acc tct agt gat acc tca tcc ata tcc cat gcc      144
 Val Gln Thr Ser Gly Thr Ser Ser Asp Thr Ser Ser Ile Ser His Ala
          35                  40                  45

 aaa cac ttg gtc aga cac agc tgg agt cct gct ggt gtt cca aca tct      192
 Lys His Leu Val Arg His Ser Trp Ser Pro Ala Gly Val Pro Thr Ser
      50                  55                  60

 ttt ggg gga aaa agc cct tta gtg ttt ata gaa gca gga aca gaa atg      240
 Phe Gly Gly Lys Ser Pro Leu Val Phe Ile Glu Ala Gly Thr Glu Met
  65                  70                  75                  80

 ctt atg aat gtc ctg cac tct ctt tct cct gaa atc ctt acc cgt gga      288
 Leu Met Asn Val Leu His Ser Leu Ser Pro Glu Ile Leu Thr Arg Gly
                  85                  90                  95

 atg caa cct act acc tgg tgt aga cac cag gtt gct ctc aaa ctt agt      336
 Met Gln Pro Thr Thr Trp Cys Arg His Gln Val Ala Leu Lys Leu Ser
             100                 105                 110

 ata cca gaa atg tcc tca ttc tgc cct tta ata aga gct gac caa atg      384
 Ile Pro Glu Met Ser Ser Phe Cys Pro Leu Ile Arg Ala Asp Gln Met
         115                 120                 125

 cta gct ggg gaa act tct cac cat ctg tca cca gcg ttc tcc ctg gaa      432
 Leu Ala Gly Glu Thr Ser His His Leu Ser Pro Ala Phe Ser Leu Glu
     130                 135                 140

 aat cat ccc ttc ctc att gga tgt tgc tgt ttc cgt ggc cag gca acc      480
 Asn His Pro Phe Leu Ile Gly Cys Cys Cys Phe Arg Gly Gln Ala Thr
 145                 150                 155                 160

 cac aac att cag tct ctg act ggt act ggt cga att gca caa aca ttt      528
 His Asn Ile Gln Ser Leu Thr Gly Thr Gly Arg Ile Ala Gln Thr Phe
                 165                 170                 175

 act gtg ccc ctg ctt gtg ctg ggc act gaa gat gca aac atg agt gag      576
 Thr Val Pro Leu Leu Val Leu Gly Thr Glu Asp Ala Asn Met Ser Glu
             180                 185                 190

 cca cag ttt gca tcc cct gta cct ccg gcc cag gga ggt aca ggg gat      624
 Pro Gln Phe Ala Ser Pro Val Pro Pro Ala Gln Gly Gly Thr Gly Asp
         195                 200                 205

 gca aac tgg aga agc gac atc tga                                      648
 Ala Asn Trp Arg Ser Asp Ile 
     210                 215





      <210> 990
      <211> 558
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(558)

      <400> 990
  atg aca ttt cag cag gta tat ctt ggt att atg act acc tgt ctc aat      48
  Met Thr Phe Gln Gln Val Tyr Leu Gly Ile Met Thr Thr Cys Leu Asn
    1               5                  10                  15

 ctg ggg cct aca ttg gag tgc aaa ttg gaa tat gtt tat ttc atg gta       96
 Leu Gly Pro Thr Leu Glu Cys Lys Leu Glu Tyr Val Tyr Phe Met Val
              20                  25                  30

 gta gaa gaa gct caa gaa ggc aag ccc aaa tgt gta ggt cca ttg tcc      144
 Val Glu Glu Ala Gln Glu Gly Lys Pro Lys Cys Val Gly Pro Leu Ser
          35                  40                  45

 aaa cca agt tac ata gcc aag agc aaa gtc aag gac ctg ctt agt caa      192
 Lys Pro Ser Tyr Ile Ala Lys Ser Lys Val Lys Asp Leu Leu Ser Gln
      50                  55                  60

 aat ctg gaa aac act tta aat aaa gtc ttt gca cag cga aaa agg atc      240
 Asn Leu Glu Asn Thr Leu Asn Lys Val Phe Ala Gln Arg Lys Arg Ile
  65                  70                  75                  80

 agc aca gat aga gag tgc cag aca cag ctg cag agt cag cct ttt ata      288
 Ser Thr Asp Arg Glu Cys Gln Thr Gln Leu Gln Ser Gln Pro Phe Ile
                  85                  90                  95

 aag aac aag aca agg ctc ttc acc ctc acg gct tct gtt cag cat tgt      336
 Lys Asn Lys Thr Arg Leu Phe Thr Leu Thr Ala Ser Val Gln His Cys
             100                 105                 110

 acc aga ggt ggt agc cag tac aat aag gca aac aat gaa ata gaa tgc      384
 Thr Arg Gly Gly Ser Gln Tyr Asn Lys Ala Asn Asn Glu Ile Glu Cys
         115                 120                 125

 atc caa gta gaa aag aaa aaa gta aaa ctg act tta tcc aaa gat gac      432
 Ile Gln Val Glu Lys Lys Lys Val Lys Leu Thr Leu Ser Lys Asp Asp
     130                 135                 140

 atg att atc tct gca gaa aat ctg gta ttt tac caa gag aaa aga aag      480
 Met Ile Ile Ser Ala Glu Asn Leu Val Phe Tyr Gln Glu Lys Arg Lys
 145                 150                 155                 160

 cat atg tct aca caa aca ctg tac att gat gtt cat aac aaa tta att      528
 His Met Ser Thr Gln Thr Leu Tyr Ile Asp Val His Asn Lys Leu Ile
                 165                 170                 175

 tat gat aat cga aag ctg gaa aca acc tag                              558
 Tyr Asp Asn Arg Lys Leu Glu Thr Thr 
             180                 185





      <210> 991
      <211> 384
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(384)

      <400> 991
  atg gcc ttc att ttt tct ttc ctc atg gtg gtc ctg gtg ctc tac gtg      48
  Met Ala Phe Ile Phe Ser Phe Leu Met Val Val Leu Val Leu Tyr Val
    1               5                  10                  15

 tcc tgg aag tgt ttc cca gcc agc ctc agg cag ctc aga cag tgc ttt       96
 Ser Trp Lys Cys Phe Pro Ala Ser Leu Arg Gln Leu Arg Gln Cys Phe
              20                  25                  30

 gtc acg cag cgc agg aag caa aag cag aaa cag acc atg cat cag atg      144
 Val Thr Gln Arg Arg Lys Gln Lys Gln Lys Gln Thr Met His Gln Met
          35                  40                  45

 gct gcc atg tct gcc cag gaa tac tac gtt gat tac aaa ccg aac cac      192
 Ala Ala Met Ser Ala Gln Glu Tyr Tyr Val Asp Tyr Lys Pro Asn His
      50                  55                  60

 att gag gga gcc ctg gtg atc atc aac gag tat ggc tcg tgt acc tgc      240
 Ile Glu Gly Ala Leu Val Ile Ile Asn Glu Tyr Gly Ser Cys Thr Cys
  65                  70                  75                  80

 cac cag cag ccc gcg agg gaa tgc gag gtt tcc agg tcc atc att gag      288
 His Gln Gln Pro Ala Arg Glu Cys Glu Val Ser Arg Ser Ile Ile Glu
                  85                  90                  95

 att tca gtt tct att gaa cta aaa agt gag gag gtg gtg gta gtg gca      336
 Ile Ser Val Ser Ile Glu Leu Lys Ser Glu Glu Val Val Val Val Ala
             100                 105                 110

 gtt gag ggt gct aat ctc att atg ctg tgc tat ctg aaa aga act taa      384
 Val Glu Gly Ala Asn Leu Ile Met Leu Cys Tyr Leu Lys Arg Thr 
         115                 120                 125





      <210> 992
      <211> 231
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(231)

      <400> 992
  atg acg gtg gtc ttg gag ccg ctg gcg ctg gtg gtg acc gtg aca aca      48
  Met Thr Val Val Leu Glu Pro Leu Ala Leu Val Val Thr Val Thr Thr
    1               5                  10                  15

 gct ggc agg gtg gct gtg gtg gtc act gcc ctg gct ttc gat ggg aga       96
 Ala Gly Arg Val Ala Val Val Val Thr Ala Leu Ala Phe Asp Gly Arg
              20                  25                  30

 gtg gag aac cac ctc ggg gga tcc agg ctt acc tac tgt ggc cag tgc      144
 Val Glu Asn His Leu Gly Gly Ser Arg Leu Thr Tyr Cys Gly Gln Cys
          35                  40                  45

 cac agg cgt cct cag gaa ggg ggt cct gcc cag ccc atg gac atg atg      192
 His Arg Arg Pro Gln Glu Gly Gly Pro Ala Gln Pro Met Asp Met Met
      50                  55                  60

 ccc aaa gta gac ggc atc agc atg acc cag tgc caa tga                  231
 Pro Lys Val Asp Gly Ile Ser Met Thr Gln Cys Gln 
  65                  70                  75





      <210> 993
      <211> 1389
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1389)

      <400> 993
  atg gga ttg cca ccc tgt ttc aag gtg ctg gcc gcc act gcc ttg tta      48
  Met Gly Leu Pro Pro Cys Phe Lys Val Leu Ala Ala Thr Ala Leu Leu
    1               5                  10                  15

 gcc aaa gat gct aac aag ctc aca ttt ggg cag cag ctg ata att cag       96
 Ala Lys Asp Ala Asn Lys Leu Thr Phe Gly Gln Gln Leu Ile Ile Gln
              20                  25                  30

 gtg ccc cac aca att gtc acc ttg atg gaa cag aga gga cat tgt tgg      144
 Val Pro His Thr Ile Val Thr Leu Met Glu Gln Arg Gly His Cys Trp
          35                  40                  45

 ctc tct aac cgt agg atg cta aga tac caa gga ctc cta tgt gag aat      192
 Leu Ser Asn Arg Arg Met Leu Arg Tyr Gln Gly Leu Leu Cys Glu Asn
      50                  55                  60

 cca tac atc acc tta gag gct gtg aat acc cta aat ctg gcc aca ctg      240
 Pro Tyr Ile Thr Leu Glu Ala Val Asn Thr Leu Asn Leu Ala Thr Leu
  65                  70                  75                  80

 tta cca ata gaa tgt gca gaa cat gga aag tcc ctg tta tgt gcc cca      288
 Leu Pro Ile Glu Cys Ala Glu His Gly Lys Ser Leu Leu Cys Ala Pro
                  85                  90                  95

 ggg tac cac tgc tgt gta gaa aca gtg gat gaa gta ttt tca agc tgg      336
 Gly Tyr His Cys Cys Val Glu Thr Val Asp Glu Val Phe Ser Ser Trp
             100                 105                 110

 gaa gac tta aag gat caa ccc tta aga aac cca gat gtt gaa tat ttt      384
 Glu Asp Leu Lys Asp Gln Pro Leu Arg Asn Pro Asp Val Glu Tyr Phe
         115                 120                 125

 act gat gga agc agc ttc ata tct gag ggt atc aaa aag gcc aga tat      432
 Thr Asp Gly Ser Ser Phe Ile Ser Glu Gly Ile Lys Lys Ala Arg Tyr
     130                 135                 140

 gcc gta gtc aca tta agc tcg gtg gct gaa gcc tgc ccc cta cca gta      480
 Ala Val Val Thr Leu Ser Ser Val Ala Glu Ala Cys Pro Leu Pro Val
 145                 150                 155                 160

 gga acc tca gcg cag aag gta gaa cta ata gct ctc aca aga gca cta      528
 Gly Thr Ser Ala Gln Lys Val Glu Leu Ile Ala Leu Thr Arg Ala Leu
                 165                 170                 175

 ttt cta gtg aag gga aag tca gtg aat atc tat gct gac tca aaa tat      576
 Phe Leu Val Lys Gly Lys Ser Val Asn Ile Tyr Ala Asp Ser Lys Tyr
             180                 185                 190

 gct ttt gcc acc ttg cat gct cat gga gcc att tac gat gaa aga gga      624
 Ala Phe Ala Thr Leu His Ala His Gly Ala Ile Tyr Asp Glu Arg Gly
         195                 200                 205

 ctg tta act act gaa gga aaa gaa ata aag aac aaa aag gaa ata gag      672
 Leu Leu Thr Thr Glu Gly Lys Glu Ile Lys Asn Lys Lys Glu Ile Glu
     210                 215                 220

 cag ctc cta gag gct gtg tgg gct cca aag gaa gta gca gtc atc cat      720
 Gln Leu Leu Glu Ala Val Trp Ala Pro Lys Glu Val Ala Val Ile His
 225                 230                 235                 240

 tgt aaa gga cag caa aca gga aga agt gat aag gct aca gga aac agc      768
 Cys Lys Gly Gln Gln Thr Gly Arg Ser Asp Lys Ala Thr Gly Asn Ser
                 245                 250                 255

 aaa gca gac aag gaa gca aga aag act gca atg aca gaa aaa aca aag      816
 Lys Ala Asp Lys Glu Ala Arg Lys Thr Ala Met Thr Glu Lys Thr Lys
             260                 265                 270

 aaa gaa gag act tat gcc atg ccc tta tta gag cct ccc ctt gca gac      864
 Lys Glu Glu Thr Tyr Ala Met Pro Leu Leu Glu Pro Pro Leu Ala Asp
         275                 280                 285

 act cct aat tac tcg tcc aat gag aag gca tcg ttt gtg cag gaa aac      912
 Thr Pro Asn Tyr Ser Ser Asn Glu Lys Ala Ser Phe Val Gln Glu Asn
     290                 295                 300

 ggg agt tat cag aaa gaa ggc tgg tgg aag ttt tca gat ggg aga ctt      960
 Gly Ser Tyr Gln Lys Glu Gly Trp Trp Lys Phe Ser Asp Gly Arg Leu
 305                 310                 315                 320

 acc att cca gaa gcc att gcc ccc caa ttt ata aag cag ttt cac caa     1008
 Thr Ile Pro Glu Ala Ile Ala Pro Gln Phe Ile Lys Gln Phe His Gln
                 325                 330                 335

 gga aca cac atg ggg aag aca gat tta aag att ctc ata ggg tat tac     1056
 Gly Thr His Met Gly Lys Thr Asp Leu Lys Ile Leu Ile Gly Tyr Tyr
             340                 345                 350

 acc tta gat cca tca cag ctg act gaa acc tgc agc ctc agt tca aga     1104
 Thr Leu Asp Pro Ser Gln Leu Thr Glu Thr Cys Ser Leu Ser Ser Arg
         355                 360                 365

 cat gtg gac gag tca gca aga tcc aga tca tcc aac tca act gat ctt     1152
 His Val Asp Glu Ser Ala Arg Ser Arg Ser Ser Asn Ser Thr Asp Leu
     370                 375                 380

 gca gag gaa cca agg cgc agt agg aaa aga cga cca ccc tgc tcc gac     1200
 Ala Glu Glu Pro Arg Arg Ser Arg Lys Arg Arg Pro Pro Cys Ser Asp
 385                 390                 395                 400

 cac acc aga agc tgg tct gtc aat gca cag ctg aag ctt aag gaa aca     1248
 His Thr Arg Ser Trp Ser Val Asn Ala Gln Leu Lys Leu Lys Glu Thr
                 405                 410                 415

 agc atc cag tct act atg gaa gca ata gtg gac cga aaa act acc acc     1296
 Ser Ile Gln Ser Thr Met Glu Ala Ile Val Asp Arg Lys Thr Thr Thr
             420                 425                 430

 aaa ata atg gca tta caa aaa tac caa cct gtc ccc cag gaa gaa tat     1344
 Lys Ile Met Ala Leu Gln Lys Tyr Gln Pro Val Pro Gln Glu Glu Tyr
         435                 440                 445

 gag cct aca cag gaa gag ata aat gat tgt ggt gct ctt tat taa         1389
 Glu Pro Thr Gln Glu Glu Ile Asn Asp Cys Gly Ala Leu Tyr 
     450                 455                 460





      <210> 994
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 994
  atg acc ttc tcc cac acc ctc tcc ttt ctc acc ggc tgc tgc cag ctg      48
  Met Thr Phe Ser His Thr Leu Ser Phe Leu Thr Gly Cys Cys Gln Leu
    1               5                  10                  15

 tct ccc ttc tta gct cct gga aac tgg ggc gag tgg aag ggt gaa agg       96
 Ser Pro Phe Leu Ala Pro Gly Asn Trp Gly Glu Trp Lys Gly Glu Arg
              20                  25                  30

 aag gtc ctg aag gtg aaa tct gat cca cag gag caa gag atg aaa acg      144
 Lys Val Leu Lys Val Lys Ser Asp Pro Gln Glu Gln Glu Met Lys Thr
          35                  40                  45

 gaa tca gag gtg gac ccc aaa ccc tca ggc ctc acc acc aac ccc atc      192
 Glu Ser Glu Val Asp Pro Lys Pro Ser Gly Leu Thr Thr Asn Pro Ile
      50                  55                  60

 tcc ccc agt agg atc cct tgc ctc atc atg agg tac ctc ttc tcc cag      240
 Ser Pro Ser Arg Ile Pro Cys Leu Ile Met Arg Tyr Leu Phe Ser Gln
  65                  70                  75                  80

 agc cca gct ttg tcc ctg gaa gga gct ccc aga agc acc gac tat cag      288
 Ser Pro Ala Leu Ser Leu Glu Gly Ala Pro Arg Ser Thr Asp Tyr Gln
                  85                  90                  95

 ccc ctc aag ggc act cac cag agc ctg tag                              318
 Pro Leu Lys Gly Thr His Gln Ser Leu 
             100                 105





      <210> 995
      <211> 381
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(381)

      <400> 995
  atg gag ata gac aga gaa gca aag gcg gtg ctc ctt gtc ctt acc ctg      48
  Met Glu Ile Asp Arg Glu Ala Lys Ala Val Leu Leu Val Leu Thr Leu
    1               5                  10                  15

 ata ctc cag ctt gaa tcc tgg ccg att ctg gga gtg gtc gct gtg gaa       96
 Ile Leu Gln Leu Glu Ser Trp Pro Ile Leu Gly Val Val Ala Val Glu
              20                  25                  30

 ata cac ggt ggt ctc gtg gga cgt gga gag gag gga gct tgg aag ctc      144
 Ile His Gly Gly Leu Val Gly Arg Gly Glu Glu Gly Ala Trp Lys Leu
          35                  40                  45

 gct tcc act gaa tct tcc cat cat gcg gct ggt ctc ata ggg gcc att      192
 Ala Ser Thr Glu Ser Ser His His Ala Ala Gly Leu Ile Gly Ala Ile
      50                  55                  60

 ccg gat ttc tat gta gtc gtg gtt ggg ctc ggt gga gaa gtt cag gaa      240
 Pro Asp Phe Tyr Val Val Val Val Gly Leu Gly Gly Glu Val Gln Glu
  65                  70                  75                  80

 ctg gat atg cct atg ccc tac acc gtg gtg aaa cca cag aag aga aat      288
 Leu Asp Met Pro Met Pro Tyr Thr Val Val Lys Pro Gln Lys Arg Asn
                  85                  90                  95

 gcc atc gtg ctt gag tgt cac tcc ctt acc tcc ctg ccc caa gac cca      336
 Ala Ile Val Leu Glu Cys His Ser Leu Thr Ser Leu Pro Gln Asp Pro
             100                 105                 110

 gat ggg cat gtg cat aac aca gtt ctg acc caa tca gac atc tag          381
 Asp Gly His Val His Asn Thr Val Leu Thr Gln Ser Asp Ile 
         115                 120                 125





      <210> 996
      <211> 510
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(510)

      <400> 996
  atg gag ggc ttt cac tgg ttt ggg ggt tta tgg agt tgg ctg ctt aat      48
  Met Glu Gly Phe His Trp Phe Gly Gly Leu Trp Ser Trp Leu Leu Asn
    1               5                  10                  15

 agg att gga tac aaa aat gct aag cac tgt act tct aat agt atg gag       96
 Arg Ile Gly Tyr Lys Asn Ala Lys His Cys Thr Ser Asn Ser Met Glu
              20                  25                  30

 aac aat gat agt cct ttg tgt gaa ctg ttt aga gag tta tac aaa ata      144
 Asn Asn Asp Ser Pro Leu Cys Glu Leu Phe Arg Glu Leu Tyr Lys Ile
          35                  40                  45

 aat gaa ttt gac act cct gat tct ctg ctc acg aaa ggc aag gag ttt      192
 Asn Glu Phe Asp Thr Pro Asp Ser Leu Leu Thr Lys Gly Lys Glu Phe
      50                  55                  60

 agg aaa tct ata cct aat atc ttt gac cat atg tgg aga acc aag aaa      240
 Arg Lys Ser Ile Pro Asn Ile Phe Asp His Met Trp Arg Thr Lys Lys
  65                  70                  75                  80

 cgt aat gaa gcc tgt tgg ttg ctc cta agt tca gtg aac aaa att atg      288
 Arg Asn Glu Ala Cys Trp Leu Leu Leu Ser Ser Val Asn Lys Ile Met
                  85                  90                  95

 aaa gaa aat gat gaa ctc agg gat tct atc tcc cag gtt cag aag cgg      336
 Lys Glu Asn Asp Glu Leu Arg Asp Ser Ile Ser Gln Val Gln Lys Arg
             100                 105                 110

 ata ctg agc ctc aaa tct gct aag att acc ctg agt gag agt ctt atc      384
 Ile Leu Ser Leu Lys Ser Ala Lys Ile Thr Leu Ser Glu Ser Leu Ile
         115                 120                 125

 tcc tgc ata aaa aga gct gaa att gtg gaa aaa cag aca caa gct ctt      432
 Ser Cys Ile Lys Arg Ala Glu Ile Val Glu Lys Gln Thr Gln Ala Leu
     130                 135                 140

 atc atg caa gtg gct gac ctg caa caa aag gtg cat gca cag cct cac      480
 Ile Met Gln Val Ala Asp Leu Gln Gln Lys Val His Ala Gln Pro His
 145                 150                 155                 160

 cat gtg tct act gtt aag cga ggg tat tga                              510
 His Val Ser Thr Val Lys Arg Gly Tyr 
                 165





      <210> 997
      <211> 495
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(495)

      <400> 997
  atg gct ttc agc ctc atg aca gcc ctg gaa ggt gtg tgc atc atg ctg      48
  Met Ala Phe Ser Leu Met Thr Ala Leu Glu Gly Val Cys Ile Met Leu
    1               5                  10                  15

 atg agg ata ccg agg gcc aaa gaa ggc ctt ggg ttc act gtc aac tgg       96
 Met Arg Ile Pro Arg Ala Lys Glu Gly Leu Gly Phe Thr Val Asn Trp
              20                  25                  30

 agc agt ctt aga gca gat gct gcc tct ccc atc ccc tcc att ggg cag      144
 Ser Ser Leu Arg Ala Asp Ala Ala Ser Pro Ile Pro Ser Ile Gly Gln
          35                  40                  45

 tgg gtg agc tac ctc tca gag gag tgt ccc aag gtt ttc ctt gtt aaa      192
 Trp Val Ser Tyr Leu Ser Glu Glu Cys Pro Lys Val Phe Leu Val Lys
      50                  55                  60

 att ggt ctg gct ggc tgc tgt gac gcg cca cac tgt cct gac ggt gca      240
 Ile Gly Leu Ala Gly Cys Cys Asp Ala Pro His Cys Pro Asp Gly Ala
  65                  70                  75                  80

 cac act gct gtg tgg agg aac aga gga gtc cag ctg gcc ttc aca tgg      288
 His Thr Ala Val Trp Arg Asn Arg Gly Val Gln Leu Ala Phe Thr Trp
                  85                  90                  95

 cag agg tca gtg atg tcc acg cgg gag tca ctg ccc acc gcc ttg gtg      336
 Gln Arg Ser Val Met Ser Thr Arg Glu Ser Leu Pro Thr Ala Leu Val
             100                 105                 110

 ctg atg cat ctc cca atc ttc ttc gtg ttt gag tat aca cgc ttc ccg      384
 Leu Met His Leu Pro Ile Phe Phe Val Phe Glu Tyr Thr Arg Phe Pro
         115                 120                 125

 gct ctc atc ctc gtg cca cag cca ggt gat gta gtc ggc gtt gac ctc      432
 Ala Leu Ile Leu Val Pro Gln Pro Gly Asp Val Val Gly Val Asp Leu
     130                 135                 140

 cgc aaa cac gaa ggg gcc atc gtg agc cag gtg cac atc acc ctc gcg      480
 Arg Lys His Glu Gly Ala Ile Val Ser Gln Val His Ile Thr Leu Ala
 145                 150                 155                 160

 gat ggc ggt gac tga                                                  495
 Asp Gly Gly Asp 






      <210> 998
      <211> 747
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(747)

      <400> 998
  atg cat ggt ctg ttt ctg ctt ttg ctt cct gcg ctg cgt gac aaa gca      48
  Met His Gly Leu Phe Leu Leu Leu Leu Pro Ala Leu Arg Asp Lys Ala
    1               5                  10                  15

 ctg tct gag ctg cct gag gct ggc tgg gaa aca ctt cca gga cac gta       96
 Leu Ser Glu Leu Pro Glu Ala Gly Trp Glu Thr Leu Pro Gly His Val
              20                  25                  30

 gag cac cag gac cac gat gag gaa gga gaa gat gag ggc cat ggt gcc      144
 Glu His Gln Asp His Asp Glu Glu Gly Glu Asp Glu Gly His Gly Ala
          35                  40                  45

 cgt gac cac ctt gtg gat ctg cac ggc gtt ctc ggc gtg ctc gcc gcc      192
 Arg Asp His Leu Val Asp Leu His Gly Val Leu Gly Val Leu Ala Ala
      50                  55                  60

 tgg aag agc cac ggt ggc agg ctc gaa tgt gcc gtc gtg ctg ccc ctc      240
 Trp Lys Ser His Gly Gly Arg Leu Glu Cys Ala Val Val Leu Pro Leu
  65                  70                  75                  80

 ccc gcc gtc cgc gag cgt ggt ggc cga gct ggc agg ggg ccc cag atc      288
 Pro Ala Val Arg Glu Arg Gly Gly Arg Ala Gly Arg Gly Pro Gln Ile
                  85                  90                  95

 act gcg gtt ggt gac ggc cga gag cag gtg gcc gct ggt ggg ctc ggc      336
 Thr Ala Val Gly Asp Gly Arg Glu Gln Val Ala Ala Gly Gly Leu Gly
             100                 105                 110

 ccc atc ctc gca cag gtg gaa ggc gta cac ggc gtc cag gac gtc ctc      384
 Pro Ile Leu Ala Gln Val Glu Gly Val His Gly Val Gln Asp Val Leu
         115                 120                 125

 gcc ctg ttc caa acc cag tcc agc gag ctg acc aca atg gcc acc ttg      432
 Ala Leu Phe Gln Thr Gln Ser Ser Glu Leu Thr Thr Met Ala Thr Leu
     130                 135                 140

 ttc ctc cgc agg cag agc gag tgc agg gag atg agg cgc ggg aag tgg      480
 Phe Leu Arg Arg Gln Ser Glu Cys Arg Glu Met Arg Arg Gly Lys Trp
 145                 150                 155                 160

 gcg aag ttc acc ttg acc aag tcg ttg tgc tcg agg tgc agc tcg ggt      528
 Ala Lys Phe Thr Leu Thr Lys Ser Leu Cys Ser Arg Cys Ser Ser Gly
                 165                 170                 175

 gag ctt aaa caa gcc ggc gaa aga gtt gcg cgc cag act ctt gag ctg      576
 Glu Leu Lys Gln Ala Gly Glu Arg Val Ala Arg Gln Thr Leu Glu Leu
             180                 185                 190

 att gta tcc gat gtc gag aaa ctt gag gct gcg gca gtc ctg gaa gat      624
 Ile Val Ser Asp Val Glu Lys Leu Glu Ala Ala Ala Val Leu Glu Asp
         195                 200                 205

 gcg cac ggg cac aaa ctg gat ggc gtt ggc ccg cat atg cag cgt gca      672
 Ala His Gly His Lys Leu Asp Gly Val Gly Pro His Met Gln Arg Ala
     210                 215                 220

 tct aag ctg aag agg cca acc aat gga atc aaa gtc acc aaa gac tgg      720
 Ser Lys Leu Lys Arg Pro Thr Asn Gly Ile Lys Val Thr Lys Asp Trp
 225                 230                 235                 240

 tgg tac ttt tca gga aaa gtc ata tga                                  747
 Trp Tyr Phe Ser Gly Lys Val Ile 
                 245





      <210> 999
      <211> 189
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(189)

      <400> 999
  atg gtg ctg gtt tat cct ttc tgc ctg cag cag ctg gcg ttg aag ctg      48
  Met Val Leu Val Tyr Pro Phe Cys Leu Gln Gln Leu Ala Leu Lys Leu
    1               5                  10                  15

 cag aaa ctg ctc cct ggg cac cat cgg aca ggc ttg ctg ctg gag cag       96
 Gln Lys Leu Leu Pro Gly His His Arg Thr Gly Leu Leu Leu Glu Gln
              20                  25                  30

 ctg caa atc cca agc atg agg gga cgg gct agg cgt cgc agt gga cct      144
 Leu Gln Ile Pro Ser Met Arg Gly Arg Ala Arg Arg Arg Ser Gly Pro
          35                  40                  45

 cag gtg ctg cat ctg aag gac aag ggc aaa gcc ctg ttc agc tga          189
 Gln Val Leu His Leu Lys Asp Lys Gly Lys Ala Leu Phe Ser 
      50                  55                  60





      <210> 1000
      <211> 162
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(162)

      <400> 1000
  atg tcc att tgc att ctg ctt gcc att tgt tac agt ttt ccc att gca      48
  Met Ser Ile Cys Ile Leu Leu Ala Ile Cys Tyr Ser Phe Pro Ile Ala
    1               5                  10                  15

 ttc tct gtc tac gct cgg gct ctt caa acc ata gta ggc aag gag aag       96
 Phe Ser Val Tyr Ala Arg Ala Leu Gln Thr Ile Val Gly Lys Glu Lys
              20                  25                  30

 gag tcc agt ata gaa ggc cac aaa ttc atg ttg ggt cac aag ggg acc      144
 Glu Ser Ser Ile Glu Gly His Lys Phe Met Leu Gly His Lys Gly Thr
          35                  40                  45

 aca atg tac agt act tag                                              162
 Thr Met Tyr Ser Thr 
      50





      <210> 1001
      <211> 489
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(489)

      <400> 1001
  atg tct cca tgc agc agc tgc tgg gcc cta ata ctt tta gag acc ctc      48
  Met Ser Pro Cys Ser Ser Cys Trp Ala Leu Ile Leu Leu Glu Thr Leu
    1               5                  10                  15

 aaa atc aca aac tat gct caa ctc acc ctc tac agt tct cat aac ttc       96
 Lys Ile Thr Asn Tyr Ala Gln Leu Thr Leu Tyr Ser Ser His Asn Phe
              20                  25                  30

 caa aat cta ttt tct tcc tca tac ctg aca cat ata ctt tct gct ccc      144
 Gln Asn Leu Phe Ser Ser Ser Tyr Leu Thr His Ile Leu Ser Ala Pro
          35                  40                  45

 tgg ccc ctt cag ctg tac tca ctc ttt gtt gag tcc ccg aca gtt acc      192
 Trp Pro Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Pro Thr Val Thr
      50                  55                  60

 att gtt cct ggc ctg gac ttc agt ctg gcc tcc cac att att cct gat      240
 Ile Val Pro Gly Leu Asp Phe Ser Leu Ala Ser His Ile Ile Pro Asp
  65                  70                  75                  80

 acc aca act gtc ccc cat gac tgt atc tct ctg atc cac ctg aca ttc      288
 Thr Thr Thr Val Pro His Asp Cys Ile Ser Leu Ile His Leu Thr Phe
                  85                  90                  95

 act cca ttt ccc cgt att tcc ttc ttt cgt gtt cct cac cct gat cac      336
 Thr Pro Phe Pro Arg Ile Ser Phe Phe Arg Val Pro His Pro Asp His
             100                 105                 110

 act tgg ttt att gat ggc agt tcc acc agg cct aat ctc cac tca cca      384
 Thr Trp Phe Ile Asp Gly Ser Ser Thr Arg Pro Asn Leu His Ser Pro
         115                 120                 125

 gca aag gaa ggc tat gct aga gta tct tcc aca tct atc att gag gct      432
 Ala Lys Glu Gly Tyr Ala Arg Val Ser Ser Thr Ser Ile Ile Glu Ala
     130                 135                 140

 acc act ctg cac ccc tcc act acc tct cag caa gct gaa ctc att gcc      480
 Thr Thr Leu His Pro Ser Thr Thr Ser Gln Gln Ala Glu Leu Ile Ala
 145                 150                 155                 160

 tta act tga                                                          489
 Leu Thr 






      <210> 1002
      <211> 981
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(981)

      <400> 1002
  atg ccc acg ttc gtg aaa ggt cac cac gtt ctg ctt ctc atc atg ggc      48
  Met Pro Thr Phe Val Lys Gly His His Val Leu Leu Leu Ile Met Gly
    1               5                  10                  15

 atg tgt cgt atc cct gag gct gag gca aga aga gag aag gaa ata agt       96
 Met Cys Arg Ile Pro Glu Ala Glu Ala Arg Arg Glu Lys Glu Ile Ser
              20                  25                  30

 ggc agt gag ttc cca cca cgt ggc aac tca atc tca act cct cct gac      144
 Gly Ser Glu Phe Pro Pro Arg Gly Asn Ser Ile Ser Thr Pro Pro Asp
          35                  40                  45

 ctg cag acc ctg cac act ctg att ctg ccc tac ctc agg acc tgc aca      192
 Leu Gln Thr Leu His Thr Leu Ile Leu Pro Tyr Leu Arg Thr Cys Thr
      50                  55                  60

 cgc ctt cca cgg ttc ctc gaa gtg aac cat ctg ttc atg cca cag gtc      240
 Arg Leu Pro Arg Phe Leu Glu Val Asn His Leu Phe Met Pro Gln Val
  65                  70                  75                  80

 gct gat ctc ttc ata aat cac cag ctg ctt tct ctc acg cag tct gtg      288
 Ala Asp Leu Phe Ile Asn His Gln Leu Leu Ser Leu Thr Gln Ser Val
                  85                  90                  95

 ggt cca ggc atg ttt ccc cct ttt ggg tcc tat gat gga gaa gag ttg      336
 Gly Pro Gly Met Phe Pro Pro Phe Gly Ser Tyr Asp Gly Glu Glu Leu
             100                 105                 110

 gga gat gag ggt tgg aac cag aca ctc tgc ttc ttt cct cgg ggc ctg      384
 Gly Asp Glu Gly Trp Asn Gln Thr Leu Cys Phe Phe Pro Arg Gly Leu
         115                 120                 125

 ggt aac ctc aac ccc aaa tca gga cag ttt cta act ctg ttc cac atg      432
 Gly Asn Leu Asn Pro Lys Ser Gly Gln Phe Leu Thr Leu Phe His Met
     130                 135                 140

 gag gta agt ttc ctg ttt cct gag tct aag aaa act gca gtg tcc att      480
 Glu Val Ser Phe Leu Phe Pro Glu Ser Lys Lys Thr Ala Val Ser Ile
 145                 150                 155                 160

 ctg gtc tcc aac gcc gta gcc ctt gta gcc gtt cag ccc tgc tct ctc      528
 Leu Val Ser Asn Ala Val Ala Leu Val Ala Val Gln Pro Cys Ser Leu
                 165                 170                 175

 cag tct tgc cgc cag ctc gca gcg ttc ata gat ctt ggc atc cac agt      576
 Gln Ser Cys Arg Gln Leu Ala Ala Phe Ile Asp Leu Gly Ile His Ser
             180                 185                 190

 gac aac cat cag cgt ggc caa ggt cac tac cac agt gcc cca ggc ctt      624
 Asp Asn His Gln Arg Gly Gln Gly His Tyr His Ser Ala Pro Gly Leu
         195                 200                 205

 cat tat ggc acc tcc cca gca gca aaa gga cac ggt ggg cac ggc cat      672
 His Tyr Gly Thr Ser Pro Ala Ala Lys Gly His Gly Gly His Gly His
     210                 215                 220

 ctg gcc tgg agc agt gac gtc acc ggc aag gct acc ttc cct ctg cgc      720
 Leu Ala Trp Ser Ser Asp Val Thr Gly Lys Ala Thr Phe Pro Leu Arg
 225                 230                 235                 240

 ctg cgc tgc ggc ccc atg ttg act att ggc gga cgg ggt ctc aaa ggc      768
 Leu Arg Cys Gly Pro Met Leu Thr Ile Gly Gly Arg Gly Leu Lys Gly
                 245                 250                 255

 gcc act gag cgt gcg cag aac cga ccc ctg cag ccc ttt agg ctg cgg      816
 Ala Thr Glu Arg Ala Gln Asn Arg Pro Leu Gln Pro Phe Arg Leu Arg
             260                 265                 270

 tgc caa aga gtc ggt ccc gaa gcg gaa gtg ctt gtt ggg gcc agg ctt      864
 Cys Gln Arg Val Gly Pro Glu Ala Glu Val Leu Val Gly Ala Arg Leu
         275                 280                 285

 tgt aac ggt ctc ctg agc agc gag cag aaa atc tgt tat cga gag aga      912
 Cys Asn Gly Leu Leu Ser Ser Glu Gln Lys Ile Cys Tyr Arg Glu Arg
     290                 295                 300

 atg gcc acc ttc ttg ctg tgc cct ccc atg gcc ttt cct ctg ctc aca      960
 Met Ala Thr Phe Leu Leu Cys Pro Pro Met Ala Phe Pro Leu Leu Thr
 305                 310                 315                 320

 cac aca gag agc aag ctc tga                                          981
 His Thr Glu Ser Lys Leu 
                 325





      <210> 1003
      <211> 312
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(312)

      <400> 1003
  atg ggg cat gct gct act atg ggc cac caa agt ctg tgt ctg gtg gta      48
  Met Gly His Ala Ala Thr Met Gly His Gln Ser Leu Cys Leu Val Val
    1               5                  10                  15

 ctg tgg tct ctt ctc cac agc tca gcc agg gca ggg atc tcc ctc aca       96
 Leu Trp Ser Leu Leu His Ser Ser Ala Arg Ala Gly Ile Ser Leu Thr
              20                  25                  30

 gac tca gct ttt agt gac ata gcc acg cag tca gta gtc ttc aaa ctt      144
 Asp Ser Ala Phe Ser Asp Ile Ala Thr Gln Ser Val Val Phe Lys Leu
          35                  40                  45

 ctt tcc ccg cga aaa aaa cat ttg aaa aat cct ttt gtg ggc ggc ggt      192
 Leu Ser Pro Arg Lys Lys His Leu Lys Asn Pro Phe Val Gly Gly Gly
      50                  55                  60

 ggc tgc gct tgg cgc acg ggg tgg gag tgg agc cca ggt cag gag cag      240
 Gly Cys Ala Trp Arg Thr Gly Trp Glu Trp Ser Pro Gly Gln Glu Gln
  65                  70                  75                  80

 gca ccg ccg cca gcg act ggg agc atg ttg gcc acc agc tcg ccg cca      288
 Ala Pro Pro Pro Ala Thr Gly Ser Met Leu Ala Thr Ser Ser Pro Pro
                  85                  90                  95

 tca ggg ccg cca cct ccg ccc tag                                      312
 Ser Gly Pro Pro Pro Pro Pro 
             100





      <210> 1004
      <211> 282
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(282)

      <400> 1004
  atg ccc ggc ctg tgt atc ttc ttt atg ttt acc cta cca aga gca gac      48
  Met Pro Gly Leu Cys Ile Phe Phe Met Phe Thr Leu Pro Arg Ala Asp
    1               5                  10                  15

 ctg agc att ttg ctg gcc gta gag aac cct tca cag gtt gta cct att       96
 Leu Ser Ile Leu Leu Ala Val Glu Asn Pro Ser Gln Val Val Pro Ile
              20                  25                  30

 agc aat gtg atg gga aac cat ttc agc agc aaa gca gca cca cca tct      144
 Ser Asn Val Met Gly Asn His Phe Ser Ser Lys Ala Ala Pro Pro Ser
          35                  40                  45

 gag agc tta cag ggt gcc tta tcc att gac ata cct gaa act aag gaa      192
 Glu Ser Leu Gln Gly Ala Leu Ser Ile Asp Ile Pro Glu Thr Lys Glu
      50                  55                  60

 ccc acc gat agc caa gga ggt gtg aca gtg aac tcg aag cta caa aat      240
 Pro Thr Asp Ser Gln Gly Gly Val Thr Val Asn Ser Lys Leu Gln Asn
  65                  70                  75                  80

 tca tgg tgc ata ctc atc atc cag aag cag cta gcc aga tag              282
 Ser Trp Cys Ile Leu Ile Ile Gln Lys Gln Leu Ala Arg 
                  85                  90





      <210> 1005
      <211> 447
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(447)

      <400> 1005
  atg ggc tca tct gtg ttg agc atc tgg atc ctc tca ccc tcc atc tac      48
  Met Gly Ser Ser Val Leu Ser Ile Trp Ile Leu Ser Pro Ser Ile Tyr
    1               5                  10                  15

 ccc atc ctg tct ccc ctc gcc atg ccc tgc ctc tcc agg acc gac ctc       96
 Pro Ile Leu Ser Pro Leu Ala Met Pro Cys Leu Ser Arg Thr Asp Leu
              20                  25                  30

 atc agg gta gtt aaa ctc cat cgc aat ctc ccg gaa gaa gaa gta gac      144
 Ile Arg Val Val Lys Leu His Arg Asn Leu Pro Glu Glu Glu Val Asp
          35                  40                  45

 atg gct gcc cca ctc cac cgc atg gac aaa gcc agc gcg tct ggg ctg      192
 Met Ala Ala Pro Leu His Arg Met Asp Lys Ala Ser Ala Ser Gly Leu
      50                  55                  60

 ttc ttg gcc cct gag gct tcg gtc aac ccc cca act ccc caa agc cgg      240
 Phe Leu Ala Pro Glu Ala Ser Val Asn Pro Pro Thr Pro Gln Ser Arg
  65                  70                  75                  80

 gct ggc atc gcg aaa aac ccg gcc cgg agc aac agc agt cca aag acg      288
 Ala Gly Ile Ala Lys Asn Pro Ala Arg Ser Asn Ser Ser Pro Lys Thr
                  85                  90                  95

 cag gtg cgg aac cga acg gca gct gct cag gcg gca gat gcg ccg gct      336
 Gln Val Arg Asn Arg Thr Ala Ala Ala Gln Ala Ala Asp Ala Pro Ala
             100                 105                 110

 aaa tcc gcc cag ctg gtc ctc cgc gga gct aac cgc ctg gag ccc cgg      384
 Lys Ser Ala Gln Leu Val Leu Arg Gly Ala Asn Arg Leu Glu Pro Arg
         115                 120                 125

 ggc tgg ggg agt gct ggc cgc atg gtc ctg acc ctt cct cgc tcc ctg      432
 Gly Trp Gly Ser Ala Gly Arg Met Val Leu Thr Leu Pro Arg Ser Leu
     130                 135                 140

 ttc ttt gac ccc tga                                                  447
 Phe Phe Asp Pro 
 145





      <210> 1006
      <211> 321
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(321)

      <400> 1006
  atg gtg gca agc ctt ttg ttc tct gac ctg ggg ttc ttg gcc tca tgg      48
  Met Val Ala Ser Leu Leu Phe Ser Asp Leu Gly Phe Leu Ala Ser Trp
    1               5                  10                  15

 att cta agg aat gga acc ttg agc cat gtg gtg agt gtt ata gct cta       96
 Ile Leu Arg Asn Gly Thr Leu Ser His Val Val Ser Val Ile Ala Leu
              20                  25                  30

 tta gaa gcc gtg ggt cac gga aga gaa ccg tgg aac cca gcc act agt      144
 Leu Glu Ala Val Gly His Gly Arg Glu Pro Trp Asn Pro Ala Thr Ser
          35                  40                  45

 gtt cag ctc gat tgg gat gaa cct ggg cac tta gcc gtg aag gaa caa      192
 Val Gln Leu Asp Trp Asp Glu Pro Gly His Leu Ala Val Lys Glu Gln
      50                  55                  60

 tgg cga gcc tct agc ccg atc cgc agc ggc gat ggg cgc ctc gct ggg      240
 Trp Arg Ala Ser Ser Pro Ile Arg Ser Gly Asp Gly Arg Leu Ala Gly
  65                  70                  75                  80

 tca gaa acg cag tgt aca ccc tgc cgg atc cag agg ggt gga agt cag      288
 Ser Glu Thr Gln Cys Thr Pro Cys Arg Ile Gln Arg Gly Gly Ser Gln
                  85                  90                  95

 tgg tgg gtc tgc gac aac ggc aat cag cag tag                          321
 Trp Trp Val Cys Asp Asn Gly Asn Gln Gln 
             100                 105





      <210> 1007
      <211> 774
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(774)

      <400> 1007
  atg gtg gtg aag cct cat gcc atc ctg agt ttc act tgt tta tgc atg      48
  Met Val Val Lys Pro His Ala Ile Leu Ser Phe Thr Cys Leu Cys Met
    1               5                  10                  15

 act ttc tcc ctg gaa gct tta gga gtt cgt ctt ttc ctt gtg tca ggg       96
 Thr Phe Ser Leu Glu Ala Leu Gly Val Arg Leu Phe Leu Val Ser Gly
              20                  25                  30

 act ggt cat ctg gat gct cag ctg cag tgc aat gtc cga gac ggc ttc      144
 Thr Gly His Leu Asp Ala Gln Leu Gln Cys Asn Val Arg Asp Gly Phe
          35                  40                  45

 ttc acc cac aga aga aac tca aca caa caa att ggc tgc agc caa gaa      192
 Phe Thr His Arg Arg Asn Ser Thr Gln Gln Ile Gly Cys Ser Gln Glu
      50                  55                  60

 aaa ggt aaa aac gca cta ggt cat agc ccc tca acc cag cca cag atc      240
 Lys Gly Lys Asn Ala Leu Gly His Ser Pro Ser Thr Gln Pro Gln Ile
  65                  70                  75                  80

 ccc tct gat gac aag acc cct gcc aga gtc tat acg act cct gag gca      288
 Pro Ser Asp Asp Lys Thr Pro Ala Arg Val Tyr Thr Thr Pro Glu Ala
                  85                  90                  95

 cac tgg act gtt ccc ccc aac ccc ggt gcc ttg ggc tac ccc cat caa      336
 His Trp Thr Val Pro Pro Asn Pro Gly Ala Leu Gly Tyr Pro His Gln
             100                 105                 110

 agt ttt gtc agt cag ccc cac ccc ttc aga aag cag ccc agt cct tgc      384
 Ser Phe Val Ser Gln Pro His Pro Phe Arg Lys Gln Pro Ser Pro Cys
         115                 120                 125

 cct cgc caa tca ccc cag ggt gac ttt ggg tgg gtg act cct ggg act      432
 Pro Arg Gln Ser Pro Gln Gly Asp Phe Gly Trp Val Thr Pro Gly Thr
     130                 135                 140

 tcc cgc tcc gtt act ggg ccc tca tct cct gcc gcc cca agc ttg atc      480
 Ser Arg Ser Val Thr Gly Pro Ser Ser Pro Ala Ala Pro Ser Leu Ile
 145                 150                 155                 160

 tcc ctg ggc tct ttg ggc tct cat ctc caa gga gcc agg ccc cac cct      528
 Ser Leu Gly Ser Leu Gly Ser His Leu Gln Gly Ala Arg Pro His Pro
                 165                 170                 175

 cgc caa tca tcc ctg ggt gac ttt ggg ctg gtg act cct ggg act ccc      576
 Arg Gln Ser Ser Leu Gly Asp Phe Gly Leu Val Thr Pro Gly Thr Pro
             180                 185                 190

 tgc tgc aga ctc tgc cct ccc ctc ctg ctg cct caa ggt cga cct ccc      624
 Cys Cys Arg Leu Cys Pro Pro Leu Leu Leu Pro Gln Gly Arg Pro Pro
         195                 200                 205

 tgg gtt ctt tgt gct ggc gtc tcc aag gag ctg ggt ccc aac cct gtg      672
 Trp Val Leu Cys Ala Gly Val Ser Lys Glu Leu Gly Pro Asn Pro Val
     210                 215                 220

 ctt ccc tcc ccc atc gtg gag cgg cga ctt aga cat ggt gct gac acg      720
 Leu Pro Ser Pro Ile Val Glu Arg Arg Leu Arg His Gly Ala Asp Thr
 225                 230                 235                 240

 gtc cct ccc cct gac cag gag gat tgg aat gtt gtg atg tca cag ccc      768
 Val Pro Pro Pro Asp Gln Glu Asp Trp Asn Val Val Met Ser Gln Pro
                 245                 250                 255

 acc tag                                                              774
 Thr 






      <210> 1008
      <211> 213
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(213)

      <400> 1008
  atg ctc cag ccg gaa cat ggc gtc cgt ctc cag ctt ctg ctt ctt ctc      48
  Met Leu Gln Pro Glu His Gly Val Arg Leu Gln Leu Leu Leu Leu Leu
    1               5                  10                  15

 atg ctc tgc aac gat cag agc tcg gct ggg ctt tgg ggg ccc cag cgc       96
 Met Leu Cys Asn Asp Gln Ser Ser Ala Gly Leu Trp Gly Pro Gln Arg
              20                  25                  30

 aga ctc agg gcc agg gcc ccc agg cag ttc gtt ccc ttc ctc gat gga      144
 Arg Leu Arg Ala Arg Ala Pro Arg Gln Phe Val Pro Phe Leu Asp Gly
          35                  40                  45

 cag aag ctg act tgt agc gtg tgt cta cca aag gac agg cag aag cag      192
 Gln Lys Leu Thr Cys Ser Val Cys Leu Pro Lys Asp Arg Gln Lys Gln
      50                  55                  60

 gag gat ctc ggc cat gat taa                                          213
 Glu Asp Leu Gly His Asp 
  65                  70





      <210> 1009
      <211> 198
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(198)

      <400> 1009
  atg ctg gac ctg tcc aag tca ttc ttt ggt ctc ttg aca ctc tgg tca      48
  Met Leu Asp Leu Ser Lys Ser Phe Phe Gly Leu Leu Thr Leu Trp Ser
    1               5                  10                  15

 ttt ggc acc ttc cca gct ttc cag agt cat ggt cac aaa tcc cta tca       96
 Phe Gly Thr Phe Pro Ala Phe Gln Ser His Gly His Lys Ser Leu Ser
              20                  25                  30

 gag gtg atc aaa gat cgt ggt tca aag cct gat gca cca gaa atg tgg      144
 Glu Val Ile Lys Asp Arg Gly Ser Lys Pro Asp Ala Pro Glu Met Trp
          35                  40                  45

 gct aaa gct gca gcc aat gca tcc act gcc cct ttc tct tct gtc agt      192
 Ala Lys Ala Ala Ala Asn Ala Ser Thr Ala Pro Phe Ser Ser Val Ser
      50                  55                  60

 atc tga                                                              198
 Ile 
  65





      <210> 1010
      <211> 318
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(318)

      <400> 1010
  atg gtt ttg gtt tgt ttg ttt ctc ccc ctg ccc caa aac cca caa cag      48
  Met Val Leu Val Cys Leu Phe Leu Pro Leu Pro Gln Asn Pro Gln Gln
    1               5                  10                  15

 tcc ctg gac cct gct gat cag aat agt tgc act cac cga tgc agc agc       96
 Ser Leu Asp Pro Ala Asp Gln Asn Ser Cys Thr His Arg Cys Ser Ser
              20                  25                  30

 aga aac acc tct tgc cca aga acc ctg gac cct ctg att gga ata gtt      144
 Arg Asn Thr Ser Cys Pro Arg Thr Leu Asp Pro Leu Ile Gly Ile Val
          35                  40                  45

 gtg ctc acc gat gca gca gca gaa aca cta gtt ttc ctc cta gat cac      192
 Val Leu Thr Asp Ala Ala Ala Glu Thr Leu Val Phe Leu Leu Asp His
      50                  55                  60

 aag gag gac caa gga atg ttg gat tta gtg gcc ctt gcc aat gca ttc      240
 Lys Glu Asp Gln Gly Met Leu Asp Leu Val Ala Leu Ala Asn Ala Phe
  65                  70                  75                  80

 tca aaa acc tgc acc ctt gcc tgt ctt cct aga aca caa aga gga cca      288
 Ser Lys Thr Cys Thr Leu Ala Cys Leu Pro Arg Thr Gln Arg Gly Pro
                  85                  90                  95

 aga aaa atc aga ttt agt ggc cct tac tga                              318
 Arg Lys Ile Arg Phe Ser Gly Pro Tyr 
             100                 105





      <210> 1011
      <211> 1053
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(1053)

      <400> 1011
  atg gct gtg gtc atc cct gct gcc ttg gga aca gct gct ctg gtg ccc      48
  Met Ala Val Val Ile Pro Ala Ala Leu Gly Thr Ala Ala Leu Val Pro
    1               5                  10                  15

 tgg tcc atc ctg agg ggg aag gca cca agg tac tgg ctc ctc cca tta       96
 Trp Ser Ile Leu Arg Gly Lys Ala Pro Arg Tyr Trp Leu Leu Pro Leu
              20                  25                  30

 ctt ctg gac cca gat aaa gtg cca atc att agt gca agg gat ctg act      144
 Leu Leu Asp Pro Asp Lys Val Pro Ile Ile Ser Ala Arg Asp Leu Thr
          35                  40                  45

 tct cca gat gct gcc ctg gcc agt ctg aca gct cag tct gga ggg tta      192
 Ser Pro Asp Ala Ala Leu Ala Ser Leu Thr Ala Gln Ser Gly Gly Leu
      50                  55                  60

 gag gag tta cac ctc aag gct gcc agt ttt gag tgg ggt cca gaa cag      240
 Glu Glu Leu His Leu Lys Ala Ala Ser Phe Glu Trp Gly Pro Glu Gln
  65                  70                  75                  80

 aag aag gct ctg cac cag gtc cag gct gct atg cca gct tct ctg cca      288
 Lys Lys Ala Leu His Gln Val Gln Ala Ala Met Pro Ala Ser Leu Pro
                  85                  90                  95

 ctt ggg cca tac gac cca gca gat cca atg gtg ctt gag gtg tca gtg      336
 Leu Gly Pro Tyr Asp Pro Ala Asp Pro Met Val Leu Glu Val Ser Val
             100                 105                 110

 gca gaa aga gat gct gtt tgg agc ctt tgg cag gcc ccc ata ggt gga      384
 Ala Glu Arg Asp Ala Val Trp Ser Leu Trp Gln Ala Pro Ile Gly Gly
         115                 120                 125

 cca cag cag agg cct cta gga ttt ttg agc aag aga cag ctc ttg gcc      432
 Pro Gln Gln Arg Pro Leu Gly Phe Leu Ser Lys Arg Gln Leu Leu Ala
     130                 135                 140

 tgt tac tgg gct ttg gtg gaa act gaa cgt ttg acg atg ggt cat caa      480
 Cys Tyr Trp Ala Leu Val Glu Thr Glu Arg Leu Thr Met Gly His Gln
 145                 150                 155                 160

 gtc acc ata cga cct gaa ctg cct gtt atg aac tgg gtg ctt tct gac      528
 Val Thr Ile Arg Pro Glu Leu Pro Val Met Asn Trp Val Leu Ser Asp
                 165                 170                 175

 tca tct agc cat aaa agg ttt atc ctc act gga ata gac att tac tcc      576
 Ser Ser Ser His Lys Arg Phe Ile Leu Thr Gly Ile Asp Ile Tyr Ser
             180                 185                 190

 aga tat gga ttt gcc tat cct gca cac aat gct tct gcc aag act acc      624
 Arg Tyr Gly Phe Ala Tyr Pro Ala His Asn Ala Ser Ala Lys Thr Thr
         195                 200                 205

 atc cgt gga cac aca gaa tgc gtt atc cac cgt cac ggt att cca cac      672
 Ile Arg Gly His Thr Glu Cys Val Ile His Arg His Gly Ile Pro His
     210                 215                 220

 agc att gcc tct gac caa ggc act cac ttt atg gct gaa gaa gtg tgg      720
 Ser Ile Ala Ser Asp Gln Gly Thr His Phe Met Ala Glu Glu Val Trp
 225                 230                 235                 240

 cag tgg gct cat gct cat gga att cac tgg tct tac gat att ccc cat      768
 Gln Trp Ala His Ala His Gly Ile His Trp Ser Tyr Asp Ile Pro His
                 245                 250                 255

 cat cct gag gca gct gga tta ata gaa tgg tgg aat ggc ctt ttg aaa      816
 His Pro Glu Ala Ala Gly Leu Ile Glu Trp Trp Asn Gly Leu Leu Lys
             260                 265                 270

 tca caa tta caa tgc caa cta ggt gat aat act ttg cag ggc tgg ggc      864
 Ser Gln Leu Gln Cys Gln Leu Gly Asp Asn Thr Leu Gln Gly Trp Gly
         275                 280                 285

 aaa gtt ctc cag aag gcc atg tat gct ctg aat cag cat caa ata tat      912
 Lys Val Leu Gln Lys Ala Met Tyr Ala Leu Asn Gln His Gln Ile Tyr
     290                 295                 300

 ggt att gtt tct ccc ata gcc aga att cac ggg tcc agg aat caa gag      960
 Gly Ile Val Ser Pro Ile Ala Arg Ile His Gly Ser Arg Asn Gln Glu
 305                 310                 315                 320

 gtg gaa gtg gat gtg gta cca cat gcc atc acc cct agt gat cca cta     1008
 Val Glu Val Asp Val Val Pro His Ala Ile Thr Pro Ser Asp Pro Leu
                 325                 330                 335

 gca aaa ttt ttg ctt cct gtt ccc cat tac att ctg gtg gcc tag         1053
 Ala Lys Phe Leu Leu Pro Val Pro His Tyr Ile Leu Val Ala 
             340                 345                 350





      <210> 1012
      <211> 954
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(954)

      <400> 1012
  atg agg ctg ggg ctc cag cag ccc ctc ctc ttg gct ctc agc ctg gtc      48
  Met Arg Leu Gly Leu Gln Gln Pro Leu Leu Leu Ala Leu Ser Leu Val
    1               5                  10                  15

 aca gat gca aag cat ttc tca cag ctg ctg ctg aga cac gga ggg gaa       96
 Thr Asp Ala Lys His Phe Ser Gln Leu Leu Leu Arg His Gly Gly Glu
              20                  25                  30

 ctg gtg att cca tta aaa gca aaa caa agg ctg gga aca gtg tac act      144
 Leu Val Ile Pro Leu Lys Ala Lys Gln Arg Leu Gly Thr Val Tyr Thr
          35                  40                  45

 ttc cgt tca gcc atc gtc aca gca cgt gct gtg tgg gtg cgg cca cgt      192
 Phe Arg Ser Ala Ile Val Thr Ala Arg Ala Val Trp Val Arg Pro Arg
      50                  55                  60

 atg gat cgc aga gcc gac ctc agc tca gcg acg cag agt gct tct gct      240
 Met Asp Arg Arg Ala Asp Leu Ser Ser Ala Thr Gln Ser Ala Ser Ala
  65                  70                  75                  80

 gaa aaa ttt gga ggg agg gtt agt gct ggc cac tgt gca ctg ccg ctg      288
 Glu Lys Phe Gly Gly Arg Val Ser Ala Gly His Cys Ala Leu Pro Leu
                  85                  90                  95

 cca gca cgc ccg gtc aca gcc agt gtc tat ggg cga ctg gcg cgg ctg      336
 Pro Ala Arg Pro Val Thr Ala Ser Val Tyr Gly Arg Leu Ala Arg Leu
             100                 105                 110

 cga ggc tgt cta gag gac tcc tac cct tct gct ctg agt gcg caa gtc      384
 Arg Gly Cys Leu Glu Asp Ser Tyr Pro Ser Ala Leu Ser Ala Gln Val
         115                 120                 125

 ttc ctg gac tct ccg gct gtg ggc tgt ggt ttg gaa acg agg ttg ttc      432
 Phe Leu Asp Ser Pro Ala Val Gly Cys Gly Leu Glu Thr Arg Leu Phe
     130                 135                 140

 ata gag gct gct ctg ggg cca cca tgc agg gca acg gtg acg tcc aga      480
 Ile Glu Ala Ala Leu Gly Pro Pro Cys Arg Ala Thr Val Thr Ser Arg
 145                 150                 155                 160

 ggc cac ctg ctt gac atc tcc atc acc aaa tct cca gga aga ccc tgt      528
 Gly His Leu Leu Asp Ile Ser Ile Thr Lys Ser Pro Gly Arg Pro Cys
                 165                 170                 175

 ttc cta tct gtg tgc ctc cat ggc agt gac cag caa aag cgc aag ggt      576
 Phe Leu Ser Val Cys Leu His Gly Ser Asp Gln Gln Lys Arg Lys Gly
             180                 185                 190

 gcc gca gcc acg gcg aaa aga aag tcc aag ggt gga ggg gtg aac gtg      624
 Ala Ala Ala Thr Ala Lys Arg Lys Ser Lys Gly Gly Gly Val Asn Val
         195                 200                 205

 gag gga cgt ctg tgc acc tgg ccc cct gaa gac cca ccc aaa tcc tgg      672
 Glu Gly Arg Leu Cys Thr Trp Pro Pro Glu Asp Pro Pro Lys Ser Trp
     210                 215                 220

 tct ctg gcc ttc ggc ccc ctg caa gag aag acc acg gag ctc aac ctc      720
 Ser Leu Ala Phe Gly Pro Leu Gln Glu Lys Thr Thr Glu Leu Asn Leu
 225                 230                 235                 240

 cac ccg cgg tgc tgg gca cgc tgc ttg agc cac tgg gag ctg cca cca      768
 His Pro Arg Cys Trp Ala Arg Cys Leu Ser His Trp Glu Leu Pro Pro
                 245                 250                 255

 ggg ccc cgg gga agg gcc cag gcc ccg gac tgg act gga tct aag tcg      816
 Gly Pro Arg Gly Arg Ala Gln Ala Pro Asp Trp Thr Gly Ser Lys Ser
             260                 265                 270

 ttt agg gaa cag ttg ctt acc ttc acg ctg tgg ggt gtt caa gag aag      864
 Phe Arg Glu Gln Leu Leu Thr Phe Thr Leu Trp Gly Val Gln Glu Lys
         275                 280                 285

 att agc aaa cat caa gca aat caa ggt aag gag gct cct gcc tac acg      912
 Ile Ser Lys His Gln Ala Asn Gln Gly Lys Glu Ala Pro Ala Tyr Thr
     290                 295                 300

 ggt ttg gag gac tcg gac cct ggg ggg ctg tgc gct gtg tag              954
 Gly Leu Glu Asp Ser Asp Pro Gly Gly Leu Cys Ala Val 
 305                 310                 315





      <210> 1013
      <211> 972
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(972)

      <400> 1013
  atg gag cag cct gcc atc tta att atc ttc atg ccc atc ttt acc atc      48
  Met Glu Gln Pro Ala Ile Leu Ile Ile Phe Met Pro Ile Phe Thr Ile
    1               5                  10                  15

 atg act atg gcc act cct cct ctc agc aat gat ggt gaa ctt ggc agt       96
 Met Thr Met Ala Thr Pro Pro Leu Ser Asn Asp Gly Glu Leu Gly Ser
              20                  25                  30

 atc gaa ccc aaa cag cct ttc tct ccc cat tac ctg caa cgt cag ctt      144
 Ile Glu Pro Lys Gln Pro Phe Ser Pro His Tyr Leu Gln Arg Gln Leu
          35                  40                  45

 ttc tgc ttc tca cac aac tct gcc cag gct cca ttg tgc cat gcg gtg      192
 Phe Cys Phe Ser His Asn Ser Ala Gln Ala Pro Leu Cys His Ala Val
      50                  55                  60

 aag caa tct aag agc gag ggc atc aca cac aat gtc gaa agg ccc ttg      240
 Lys Gln Ser Lys Ser Glu Gly Ile Thr His Asn Val Glu Arg Pro Leu
  65                  70                  75                  80

 gca gcc aca ggg tca cca cct ggc act cca atg caa gca aac ctt ctt      288
 Ala Ala Thr Gly Ser Pro Pro Gly Thr Pro Met Gln Ala Asn Leu Leu
                  85                  90                  95

 cag tca atc acc atg cac ctc cct aag atc ctc cag ggc ctt cct gga      336
 Gln Ser Ile Thr Met His Leu Pro Lys Ile Leu Gln Gly Leu Pro Gly
             100                 105                 110

 agc tgg tgg ctg gct gtc aag cag ggc ccc cag aac caa cag ggg aag      384
 Ser Trp Trp Leu Ala Val Lys Gln Gly Pro Gln Asn Gln Gln Gly Lys
         115                 120                 125

 ttg gtt gct aat ggc aac agt ctt ggg agc aag gaa aga aag aaa tca      432
 Leu Val Ala Asn Gly Asn Ser Leu Gly Ser Lys Glu Arg Lys Lys Ser
     130                 135                 140

 tct gtc aaa ggt tac caa gct att aag tgg gaa agc ttg gtg gag aag      480
 Ser Val Lys Gly Tyr Gln Ala Ile Lys Trp Glu Ser Leu Val Glu Lys
 145                 150                 155                 160

 gat gat ttc cgg act cgc tgt cca gtg atc cat ctg ctg cag gtg gaa      528
 Asp Asp Phe Arg Thr Arg Cys Pro Val Ile His Leu Leu Gln Val Glu
                 165                 170                 175

 tcc ttc cgc cac aca aat gcc tcc aag acc ggc agt tcc gag gtt ggc      576
 Ser Phe Arg His Thr Asn Ala Ser Lys Thr Gly Ser Ser Glu Val Gly
             180                 185                 190

 aga acc cgt tgc ttg ttg ggg att gtc ctg gat gtg ggg gat gga tgt      624
 Arg Thr Arg Cys Leu Leu Gly Ile Val Leu Asp Val Gly Asp Gly Cys
         195                 200                 205

 gtg aac aag aga gct gtg gtc cct gct tcc tgg agg ttt gtc acc tgt      672
 Val Asn Lys Arg Ala Val Val Pro Ala Ser Trp Arg Phe Val Thr Cys
     210                 215                 220

 ggg gaa gca gat gac tcc att agt acc tac aag atc caa cgt gac aag      720
 Gly Glu Ala Asp Asp Ser Ile Ser Thr Tyr Lys Ile Gln Arg Asp Lys
 225                 230                 235                 240

 ggt gag ccc cca gaa cct gaa atc caa gtc cca gcc cat aag ggt tcc      768
 Gly Glu Pro Pro Glu Pro Glu Ile Gln Val Pro Ala His Lys Gly Ser
                 245                 250                 255

 gtg aac acg ctc atg tgc ttg ttc tta cta gac aaa gat aac gaa tca      816
 Val Asn Thr Leu Met Cys Leu Phe Leu Leu Asp Lys Asp Asn Glu Ser
             260                 265                 270

 ctg tgt tca atc act gtg gat gct ctg atc agc caa gcc agc ctg agt      864
 Leu Cys Ser Ile Thr Val Asp Ala Leu Ile Ser Gln Ala Ser Leu Ser
         275                 280                 285

 tcg gcc tca ctg gag cca aca gga agg cag agc cag ttc cag aaa gga      912
 Ser Ala Ser Leu Glu Pro Thr Gly Arg Gln Ser Gln Phe Gln Lys Gly
     290                 295                 300

 gag tca ggt tta gtc ccc aaa gaa gag gga atc cat gct gaa cat gca      960
 Glu Ser Gly Leu Val Pro Lys Glu Glu Gly Ile His Ala Glu His Ala
 305                 310                 315                 320

 aaa tca tgt tag                                                      972
 Lys Ser Cys 






      <210> 1014
      <211> 744
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(744)

      <400> 1014
  atg ggc cgg gcg tgg tgg ctc aca cct gta atc cca gca ctt tgg gag      48
  Met Gly Arg Ala Trp Trp Leu Thr Pro Val Ile Pro Ala Leu Trp Glu
    1               5                  10                  15

 gcc aag gct ggc aga aca cga gga gga agc atg caa gca aaa gag gtg       96
 Ala Lys Ala Gly Arg Thr Arg Gly Gly Ser Met Gln Ala Lys Glu Val
              20                  25                  30

 gga agt gga gtg cac gag tgc tgg aac cag ctg acc aat tca gtg cca      144
 Gly Ser Gly Val His Glu Cys Trp Asn Gln Leu Thr Asn Ser Val Pro
          35                  40                  45

 gca gga tca aac ttc act cac tct gac ctg cct cat tgc acc cct tgc      192
 Ala Gly Ser Asn Phe Thr His Ser Asp Leu Pro His Cys Thr Pro Cys
      50                  55                  60

 gga agg gag cac aca ggt gag tgg gtg cag gag cca cag cta gcc ctt      240
 Gly Arg Glu His Thr Gly Glu Trp Val Gln Glu Pro Gln Leu Ala Leu
  65                  70                  75                  80

 ttg ggc act ggc gca agc gaa ctc cat gca gga cct gca gca tct agt      288
 Leu Gly Thr Gly Ala Ser Glu Leu His Ala Gly Pro Ala Ala Ser Ser
                  85                  90                  95

 tgg gag tgc atg aga ccc ctg aag ccc cag agg gct gtg gct cag gct      336
 Trp Glu Cys Met Arg Pro Leu Lys Pro Gln Arg Ala Val Ala Gln Ala
             100                 105                 110

 gtg gtt tca gag ggt gca agc ctc aag ccc tgg cag ctt cca tgg ggt      384
 Val Val Ser Glu Gly Ala Ser Leu Lys Pro Trp Gln Leu Pro Trp Gly
         115                 120                 125

 gtt gag cct gcc agt gca aag aag tca aga att ggg gtt tgg gag cct      432
 Val Glu Pro Ala Ser Ala Lys Lys Ser Arg Ile Gly Val Trp Glu Pro
     130                 135                 140

 ccg cct gga ttc cag agg atg tat gga aac acc tgg atg tcc agg cag      480
 Pro Pro Gly Phe Gln Arg Met Tyr Gly Asn Thr Trp Met Ser Arg Gln
 145                 150                 155                 160

 aag ttt gct gca ggg gca ggg atc tca tgg gga act tct tct agg gca      528
 Lys Phe Ala Ala Gly Ala Gly Ile Ser Trp Gly Thr Ser Ser Arg Ala
                 165                 170                 175

 gtg cag gag gga aat gtg tgg ttg gag ccc cca cac aga gtt cct act      576
 Val Gln Glu Gly Asn Val Trp Leu Glu Pro Pro His Arg Val Pro Thr
             180                 185                 190

 ggg gca aca cct agt tgg gct gtg aga aga aag cca cca tcc tcc aga      624
 Gly Ala Thr Pro Ser Trp Ala Val Arg Arg Lys Pro Pro Ser Ser Arg
         195                 200                 205

 ccc cag aat gat aga tcc atc gat cac ttg tac cgt gca cct gga aaa      672
 Pro Gln Asn Asp Arg Ser Ile Asp His Leu Tyr Arg Ala Pro Gly Lys
     210                 215                 220

 gcc aca gac act cat gcc tgc cat gac agc agc cag gag agg ggt tat      720
 Ala Thr Asp Thr His Ala Cys His Asp Ser Ser Gln Glu Arg Gly Tyr
 225                 230                 235                 240

 acc ctg caa agc cac aga ggc tga                                      744
 Thr Leu Gln Ser His Arg Gly 
                 245





      <210> 1015
      <211> 465
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(465)

      <400> 1015
  atg ctg gtt tgc tgc acc cat cag cct gtc acc tac att cgg tat tct      48
  Met Leu Val Cys Cys Thr His Gln Pro Val Thr Tyr Ile Arg Tyr Ser
    1               5                  10                  15

 ccc aat gtt att cct ccc cta gcc cca cac acc ctg cag gcc ctg tta       96
 Pro Asn Val Ile Pro Pro Leu Ala Pro His Thr Leu Gln Ala Leu Leu
              20                  25                  30

 ttt ctt gtc ttc tac gag ctt tta aat ttg ttt gct ctt gag ggt gga      144
 Phe Leu Val Phe Tyr Glu Leu Leu Asn Leu Phe Ala Leu Glu Gly Gly
          35                  40                  45

 gcc aag att gcc gaa gag gag cag ctc cag tct aca gct ccc agc cct      192
 Ala Lys Ile Ala Glu Glu Glu Gln Leu Gln Ser Thr Ala Pro Ser Pro
      50                  55                  60

 ctg ctg ctg ata ccc agg cac acg ggg tct gga gtg gac ttc aag caa      240
 Leu Leu Leu Ile Pro Arg His Thr Gly Ser Gly Val Asp Phe Lys Gln
  65                  70                  75                  80

 act cca aca gac ctg cag ctg agg gtc ctg aat gtt aga agg aaa act      288
 Thr Pro Thr Asp Leu Gln Leu Arg Val Leu Asn Val Arg Arg Lys Thr
                  85                  90                  95

 aac aaa cag aaa gga cat cca cac caa aaa ccc ctc tgt acg tca cca      336
 Asn Lys Gln Lys Gly His Pro His Gln Lys Pro Leu Cys Thr Ser Pro
             100                 105                 110

 tca tca aag acc aaa gga atg cag ctc ctc acc aca acg gaa caa agt      384
 Ser Ser Lys Thr Lys Gly Met Gln Leu Leu Thr Thr Thr Glu Gln Ser
         115                 120                 125

 tgg aca gag aat gac ttt gac aag ttg aca aaa gat ggc ttc aga aga      432
 Trp Thr Glu Asn Asp Phe Asp Lys Leu Thr Lys Asp Gly Phe Arg Arg
     130                 135                 140

 tca aac aaa tct gag cta aag gaa gaa gtt tga                          465
 Ser Asn Lys Ser Glu Leu Lys Glu Glu Val 
 145                 150





      <210> 1016
      <211> 807
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(807)

      <400> 1016
  atg aag ccc cgc gcg cgc gga tgg cgg ggc ttg gcg gcg ctg tgg atg      48
  Met Lys Pro Arg Ala Arg Gly Trp Arg Gly Leu Ala Ala Leu Trp Met
    1               5                  10                  15

 ctg ctg gcg cag gtg gcc gag cag gtg agt ccc ggg cgc tcc cac cag       96
 Leu Leu Ala Gln Val Ala Glu Gln Val Ser Pro Gly Arg Ser His Gln
              20                  25                  30

 cgc gga aac cgc ggg tcc gga cag ctg gag gcg agt ccc ccg cgg ctc      144
 Arg Gly Asn Arg Gly Ser Gly Gln Leu Glu Ala Ser Pro Pro Arg Leu
          35                  40                  45

 ctc tcc cgc gga ccc cgc cgt ctc acc gcg atg tcg ccg ctg ttt tcc      192
 Leu Ser Arg Gly Pro Arg Arg Leu Thr Ala Met Ser Pro Leu Phe Ser
      50                  55                  60

 gca ggc acc tgc gtg cgc cat ggg acc cgc agc ggc agc gcc tgg gag      240
 Ala Gly Thr Cys Val Arg His Gly Thr Arg Ser Gly Ser Ala Trp Glu
  65                  70                  75                  80

 ccc gag cgt ccc gcg tcc tcc tcc acc cgc gga gcg gcc ggg ctg gat      288
 Pro Glu Arg Pro Ala Ser Ser Ser Thr Arg Gly Ala Ala Gly Leu Asp
                  85                  90                  95

 gga aaa ggg cgg gac atg gat gaa gct gga aac cat cgt tct cag caa      336
 Gly Lys Gly Arg Asp Met Asp Glu Ala Gly Asn His Arg Ser Gln Gln
             100                 105                 110

 act aac aca gga aca gaa aac caa aca ctg cat gtt ctc act caa tat      384
 Thr Asn Thr Gly Thr Glu Asn Gln Thr Leu His Val Leu Thr Gln Tyr
         115                 120                 125

 gac ctg gtc tct gcc tac gag gtt gac cac agg ggc gat tac gtg tcc      432
 Asp Leu Val Ser Ala Tyr Glu Val Asp His Arg Gly Asp Tyr Val Ser
     130                 135                 140

 cat gaa atc atg cac cat cag cgg cgg aga aga gca gtg gcc gtg tcc      480
 His Glu Ile Met His His Gln Arg Arg Arg Arg Ala Val Ala Val Ser
 145                 150                 155                 160

 gag gtt gag tct ctt cac ctt cgg ctg aaa ggc ccc agg cac gac ttc      528
 Glu Val Glu Ser Leu His Leu Arg Leu Lys Gly Pro Arg His Asp Phe
                 165                 170                 175

 cac atg gat ctg agg act tcc agc agc cta gtg gct cct ggc ttt att      576
 His Met Asp Leu Arg Thr Ser Ser Ser Leu Val Ala Pro Gly Phe Ile
             180                 185                 190

 gtg cag acg ttg gga aag aca ggc act aag tct gtg cag act tta ccg      624
 Val Gln Thr Leu Gly Lys Thr Gly Thr Lys Ser Val Gln Thr Leu Pro
         195                 200                 205

 cca gag gac ttc tgt ttc tat caa ggc tct ttg cga tca cac aga aac      672
 Pro Glu Asp Phe Cys Phe Tyr Gln Gly Ser Leu Arg Ser His Arg Asn
     210                 215                 220

 tcg ctc agt ggc cct ttc aac ctg cca agg ctt ggt gag tac agc gca      720
 Ser Leu Ser Gly Pro Phe Asn Leu Pro Arg Leu Gly Glu Tyr Ser Ala
 225                 230                 235                 240

 agc ccc aga att att gtg gac gag cac ttc agc ttg aaa ctt gtg tat      768
 Ser Pro Arg Ile Ile Val Asp Glu His Phe Ser Leu Lys Leu Val Tyr
                 245                 250                 255

 aag aac cgc tgg cca aat ctg aat tct tta gct tct tag                  807
 Lys Asn Arg Trp Pro Asn Leu Asn Ser Leu Ala Ser 
             260                 265





      <210> 1017
      <211> 474
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(474)

      <400> 1017
  atg ccc cga gtc agg aaa cta aaa tac ctc ttg gtc tgg gta gac act      48
  Met Pro Arg Val Arg Lys Leu Lys Tyr Leu Leu Val Trp Val Asp Thr
    1               5                  10                  15

 ttc act gga tgg gta gag gcc ttt ccc aca ggg tct gag aag tcc act       96
 Phe Thr Gly Trp Val Glu Ala Phe Pro Thr Gly Ser Glu Lys Ser Thr
              20                  25                  30

 gca atc att tct tcc ctt ctg tca gac ata att cct tgg ttt ggc ctt      144
 Ala Ile Ile Ser Ser Leu Leu Ser Asp Ile Ile Pro Trp Phe Gly Leu
          35                  40                  45

 ccc acg tct ata cag tcc aat aac aga cca gct ttt att agt caa atc      192
 Pro Thr Ser Ile Gln Ser Asn Asn Arg Pro Ala Phe Ile Ser Gln Ile
      50                  55                  60

 acc caa gca gtt tct cag gct ctt ggt att cag tgg aac cgt cat aac      240
 Thr Gln Ala Val Ser Gln Ala Leu Gly Ile Gln Trp Asn Arg His Asn
  65                  70                  75                  80

 cct tac cgt tct caa tct tca gga aag gta aaa tgg act att ggt ctt      288
 Pro Tyr Arg Ser Gln Ser Ser Gly Lys Val Lys Trp Thr Ile Gly Leu
                  85                  90                  95

 tta aaa aca cac ctc acc aag ctc agc ctc caa ctt aaa aag gac tgg      336
 Leu Lys Thr His Leu Thr Lys Leu Ser Leu Gln Leu Lys Lys Asp Trp
             100                 105                 110

 aca ata ctt tta cca ctt gcc ctt ctc aga att cag gcc tgt cct cag      384
 Thr Ile Leu Leu Pro Leu Ala Leu Leu Arg Ile Gln Ala Cys Pro Gln
         115                 120                 125

 gat gct aca ggg tac agc cca ttt gag ctc ctg tat gga cgt tcc att      432
 Asp Ala Thr Gly Tyr Ser Pro Phe Glu Leu Leu Tyr Gly Arg Ser Ile
     130                 135                 140

 tta tta ggc ccc agt atc att cca gac acc agc cca act tga              474
 Leu Leu Gly Pro Ser Ile Ile Pro Asp Thr Ser Pro Thr 
 145                 150                 155





      <210> 1018
      <211> 177
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(177)

      <400> 1018
  atg ctt gtg acc ctg cag ctc ctc aaa gcc cag atg ttg aca gct gcc      48
  Met Leu Val Thr Leu Gln Leu Leu Lys Ala Gln Met Leu Thr Ala Ala
    1               5                  10                  15

 tct gga ggg tta tgg gag cct gtg aat gcc aac atc ccc att gcc tgc       96
 Ser Gly Gly Leu Trp Glu Pro Val Asn Ala Asn Ile Pro Ile Ala Cys
              20                  25                  30

 agc ggc tgc tcc cat cct ggc ttc ctg gtg gga ctt ttc cat gaa ttg      144
 Ser Gly Cys Ser His Pro Gly Phe Leu Val Gly Leu Phe His Glu Leu
          35                  40                  45

 ggg aat ctg ctt tct gat tcc aag gcc tat taa                          177
 Gly Asn Leu Leu Ser Asp Ser Lys Ala Tyr 
      50                  55





      <210> 1019
      <211> 624
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(624)

      <400> 1019
  atg gtc cac tat ttc cta agg gtg tcc tac gtg gct ctg acc ttg ggc      48
  Met Val His Tyr Phe Leu Arg Val Ser Tyr Val Ala Leu Thr Leu Gly
    1               5                  10                  15

 agc ctg gct ggc aga ggg aga caa aaa caa tca tca gtg gca aat ggt       96
 Ser Leu Ala Gly Arg Gly Arg Gln Lys Gln Ser Ser Val Ala Asn Gly
              20                  25                  30

 act tgc agc aaa gca aca cca aga ccc agc ttc aca ctc agg aca gaa      144
 Thr Cys Ser Lys Ala Thr Pro Arg Pro Ser Phe Thr Leu Arg Thr Glu
          35                  40                  45

 cac tgc atg tcc tcc tca tgg ttg cca gtg ttc tac acg ttc agg gga      192
 His Cys Met Ser Ser Ser Trp Leu Pro Val Phe Tyr Thr Phe Arg Gly
      50                  55                  60

 act tct cta ggc atc tct aaa aga aag gca gca gcc cca gtc agg gcc      240
 Thr Ser Leu Gly Ile Ser Lys Arg Lys Ala Ala Ala Pro Val Arg Ala
  65                  70                  75                  80

 tta gag ata aaa cac cca tct ccc tgg aac aga gca cct tgg gga agg      288
 Leu Glu Ile Lys His Pro Ser Pro Trp Asn Arg Ala Pro Trp Gly Arg
                  85                  90                  95

 ggc aac tgt ggg tat aga ttc agc aga ctt gaa gtt tcc tgc ctg cca      336
 Gly Asn Cys Gly Tyr Arg Phe Ser Arg Leu Glu Val Ser Cys Leu Pro
             100                 105                 110

 gct gtg aag aaa gca gca gat atc cca gca gag cac tcg agc tct gca      384
 Ala Val Lys Lys Ala Ala Asp Ile Pro Ala Glu His Ser Ser Ser Ala
         115                 120                 125

 aag gga cag att gcc tcc tca aga gac acc tcc cag aca ggg gtt gac      432
 Lys Gly Gln Ile Ala Ser Ser Arg Asp Thr Ser Gln Thr Gly Val Asp
     130                 135                 140

 aga cac ctc ata cag gag agc tcc aac tgg cat ctg gca agt gcc cct      480
 Arg His Leu Ile Gln Glu Ser Ser Asn Trp His Leu Ala Ser Ala Pro
 145                 150                 155                 160

 ctg gaa cga agc tgc cag agg aag gaa cag gca gca atc ttt gct att      528
 Leu Glu Arg Ser Cys Gln Arg Lys Glu Gln Ala Ala Ile Phe Ala Ile
                 165                 170                 175

 ctg cag cct ctg ctg gtg ata agc agg caa aca ggg tct gga gtg gac      576
 Leu Gln Pro Leu Leu Val Ile Ser Arg Gln Thr Gly Ser Gly Val Asp
             180                 185                 190

 ctc cag caa att cca aca gac gct gca gca gag ggt cct gac tgt tag      624
 Leu Gln Gln Ile Pro Thr Asp Ala Ala Ala Glu Gly Pro Asp Cys 
         195                 200                 205





      <210> 1020
      <211> 183
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(183)

      <400> 1020
  atg ggt ctg ccg cgt cac ctg ctg caa gcc tgc acg ctc gcg gga ccg      48
  Met Gly Leu Pro Arg His Leu Leu Gln Ala Cys Thr Leu Ala Gly Pro
    1               5                  10                  15

 tgg cta ctg gag gct tct ccc cac cag tgt gct ctc tgc cac tac ttc       96
 Trp Leu Leu Glu Ala Ser Pro His Gln Cys Ala Leu Cys His Tyr Phe
              20                  25                  30

 ctt tgt ctc tgt ggc ttc gtg ctg tct ggc tgg gct aag att tcc agc      144
 Leu Cys Leu Cys Gly Phe Val Leu Ser Gly Trp Ala Lys Ile Ser Ser
          35                  40                  45

 ttt gaa gat gga tca gtg ggc atc tca ggc cct ctc tga                  183
 Phe Glu Asp Gly Ser Val Gly Ile Ser Gly Pro Leu 
      50                  55                  60





      <210> 1021
      <211> 273
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(273)

      <400> 1021
  atg cct gct act tgg cct tgt gta cgc tcg cgc tcg tgc gct tgt gcg      48
  Met Pro Ala Thr Trp Pro Cys Val Arg Ser Arg Ser Cys Ala Cys Ala
    1               5                  10                  15

 ctc tct ctc gct ctc gct ctc tct ctc atg ctg att ctg cag gca ttc       96
 Leu Ser Leu Ala Leu Ala Leu Ser Leu Met Leu Ile Leu Gln Ala Phe
              20                  25                  30

 tac agg cct ccc atg tcc cag gag cca gct ctg tcc aca gtg ctc ttc      144
 Tyr Arg Pro Pro Met Ser Gln Glu Pro Ala Leu Ser Thr Val Leu Phe
          35                  40                  45

 ctg ctc ctg ctc ctg gcc aac cct cca acc aag gtg tct agg agc cac      192
 Leu Leu Leu Leu Leu Ala Asn Pro Pro Thr Lys Val Ser Arg Ser His
      50                  55                  60

 agg gaa gag cgg gtt ctc ttg cta gtt gct ctt cca cta ggc tgt gac      240
 Arg Glu Glu Arg Val Leu Leu Leu Val Ala Leu Pro Leu Gly Cys Asp
  65                  70                  75                  80

 acg ctg gcc gag ctc cgc ctc cac cgg ctc tga                          273
 Thr Leu Ala Glu Leu Arg Leu His Arg Leu 
                  85                  90





      <210> 1022
      <211> 681
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(681)

      <400> 1022
  atg ctg gtt gca gtg tgg gag gct ctg ctg ggg ctg cat gtt cca tgg      48
  Met Leu Val Ala Val Trp Glu Ala Leu Leu Gly Leu His Val Pro Trp
    1               5                  10                  15

 agc cag caa ggg ctg gaa gca ggc agg agc ccc act ctt ctg ggc aca       96
 Ser Gln Gln Gly Leu Glu Ala Gly Arg Ser Pro Thr Leu Leu Gly Thr
              20                  25                  30

 gct gca gct acc caa gtt gcg gct gca gac ctg ggc atc tct gca ctc      144
 Ala Ala Ala Thr Gln Val Ala Ala Ala Asp Leu Gly Ile Ser Ala Leu
          35                  40                  45

 tcg ggg gcc tgg gaa ggc tcc cgt gcc cct gca ggc tca ggg tgt ctg      192
 Ser Gly Ala Trp Glu Gly Ser Arg Ala Pro Ala Gly Ser Gly Cys Leu
      50                  55                  60

 ctt cca atg tct gga ctc tca ctg ctc ctg gtg cct gct ctg att tca      240
 Leu Pro Met Ser Gly Leu Ser Leu Leu Leu Val Pro Ala Leu Ile Ser
  65                  70                  75                  80

 gag caa ggc cta gat aat ata tta ctt agc ctt gag aaa ctg aga aat      288
 Glu Gln Gly Leu Asp Asn Ile Leu Leu Ser Leu Glu Lys Leu Arg Asn
                  85                  90                  95

 ccc cca ctg tgt cac ctt cta gag ccc ctg tca acc ctt tgc aac tcc      336
 Pro Pro Leu Cys His Leu Leu Glu Pro Leu Ser Thr Leu Cys Asn Ser
             100                 105                 110

 aag aga caa gtc act cct act ttc cag aaa aca ttc aga agc aag cac      384
 Lys Arg Gln Val Thr Pro Thr Phe Gln Lys Thr Phe Arg Ser Lys His
         115                 120                 125

 cag ccc ttc ccc aga ggt caa gca gca gaa agg gcc ttc cac tgc agt      432
 Gln Pro Phe Pro Arg Gly Gln Ala Ala Glu Arg Ala Phe His Cys Ser
     130                 135                 140

 aaa cat ttg ttg aac aac tac ttc ctg caa gtc act gga caa gta aca      480
 Lys His Leu Leu Asn Asn Tyr Phe Leu Gln Val Thr Gly Gln Val Thr
 145                 150                 155                 160

 tgg atg cag ctg gca gcc att atc ctt agc aaa cta atg cag gaa cag      528
 Trp Met Gln Leu Ala Ala Ile Ile Leu Ser Lys Leu Met Gln Glu Gln
                 165                 170                 175

 aaa acc aaa tac cag atg ttc tca ctt tat aag tgg gag cta aat gat      576
 Lys Thr Lys Tyr Gln Met Phe Ser Leu Tyr Lys Trp Glu Leu Asn Asp
             180                 185                 190

 gag aac aaa cag aca cat aga ggg gaa caa cag aca cag gtg cct act      624
 Glu Asn Lys Gln Thr His Arg Gly Glu Gln Gln Thr Gln Val Pro Thr
         195                 200                 205

 gga gag tgg agg gtg gaa aaa gga aga gga tca ggg aaa ata att aat      672
 Gly Glu Trp Arg Val Glu Lys Gly Arg Gly Ser Gly Lys Ile Ile Asn
     210                 215                 220

 gag tac tag                                                          681
 Glu Tyr 
 225





      <210> 1023
      <211> 798
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(798)

      <400> 1023
  atg ctg acg ccg ggt ctc aca cct ctc ctg ggt ggc ctt tca aga gct      48
  Met Leu Thr Pro Gly Leu Thr Pro Leu Leu Gly Gly Leu Ser Arg Ala
    1               5                  10                  15

 ctg ggc gct cag ggg ctg ccg cct ctt gca aat ttc ctc ctg gga aac       96
 Leu Gly Ala Gln Gly Leu Pro Pro Leu Ala Asn Phe Leu Leu Gly Asn
              20                  25                  30

 aga ggc ttg gac gcc cat att aac ttg tca ctg cat ctc cga agt gag      144
 Arg Gly Leu Asp Ala His Ile Asn Leu Ser Leu His Leu Arg Ser Glu
          35                  40                  45

 gag gcc cct ttg gaa gag aca gag gcg gcg gcg acc cac gag tcc cgt      192
 Glu Ala Pro Leu Glu Glu Thr Glu Ala Ala Ala Thr His Glu Ser Arg
      50                  55                  60

 tcc gga ggc tac ggg tct gag ccg gcg aga gaa aga gcg agc agc caa      240
 Ser Gly Gly Tyr Gly Ser Glu Pro Ala Arg Glu Arg Ala Ser Ser Gln
  65                  70                  75                  80

 gga agg aaa gga gac agc agc gaa gga agg aga gaa gaa ggg cgc aag      288
 Gly Arg Lys Gly Asp Ser Ser Glu Gly Arg Arg Glu Glu Gly Arg Lys
                  85                  90                  95

 ggt ccc aag acg tct cca ccg aga ggc agc tgc cac cct gct cgc gag      336
 Gly Pro Lys Thr Ser Pro Pro Arg Gly Ser Cys His Pro Ala Arg Glu
             100                 105                 110

 cac cgc agt gtc acc cgc gac gca gca gag gtg cgg caa gag ccc ccg      384
 His Arg Ser Val Thr Arg Asp Ala Ala Glu Val Arg Gln Glu Pro Pro
         115                 120                 125

 aaa ggt ctc tct tgg ggt gac agt cac cgc tgc cca gaa ggc ccc cgg      432
 Lys Gly Leu Ser Trp Gly Asp Ser His Arg Cys Pro Glu Gly Pro Arg
     130                 135                 140

 act gag agc acc tta gcg cct gcg ggt ctg cac atg ctc cgt gag cta      480
 Thr Glu Ser Thr Leu Ala Pro Ala Gly Leu His Met Leu Arg Glu Leu
 145                 150                 155                 160

 gat aga ggc aag gct gtg gcc gtg ggg cgc ggg cgc cgg gac gcg cgg      528
 Asp Arg Gly Lys Ala Val Ala Val Gly Arg Gly Arg Arg Asp Ala Arg
                 165                 170                 175

 ctg gcg ggc cgg gca ggg ctg cgc tcg gga gcg gcc gcc gcg ctt ccc      576
 Leu Ala Gly Arg Ala Gly Leu Arg Ser Gly Ala Ala Ala Ala Leu Pro
             180                 185                 190

 ggg aag gct gcg ctg gct gcg ggg ctc agc gca ggg gag gac agg ctg      624
 Gly Lys Ala Ala Leu Ala Ala Gly Leu Ser Ala Gly Glu Asp Arg Leu
         195                 200                 205

 ctg ccg gcg ctg ctg cgg cgc gcg ctg aca gcc ggg gcc gcc ccg gcg      672
 Leu Pro Ala Leu Leu Arg Arg Ala Leu Thr Ala Gly Ala Ala Pro Ala
     210                 215                 220

 cgc cca ttg gtc cac ggg cca cca ggc act gag ctg cga tgc tcc cca      720
 Arg Pro Leu Val His Gly Pro Pro Gly Thr Glu Leu Arg Cys Ser Pro
 225                 230                 235                 240

 cct ccc cac ggc tct ctc aac aca ttt cct ctt ttg gtt act gct gtc      768
 Pro Pro His Gly Ser Leu Asn Thr Phe Pro Leu Leu Val Thr Ala Val
                 245                 250                 255

 atc ctg gaa gcc ttc atg cct acc ctc tga                              798
 Ile Leu Glu Ala Phe Met Pro Thr Leu 
             260                 265





      <210> 1024
      <211> 327
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(327)

      <400> 1024
  atg agg gat caa cag tcg aaa ctg aag ctg ctc ttg ctc tgt gtc ttc      48
  Met Arg Asp Gln Gln Ser Lys Leu Lys Leu Leu Leu Leu Cys Val Phe
    1               5                  10                  15

 tct atg tgc ata aag cgt tgt tcc atc cag tgc ctg cat gag tcg tgc       96
 Ser Met Cys Ile Lys Arg Cys Ser Ile Gln Cys Leu His Glu Ser Cys
              20                  25                  30

 ctg aaa atc atg tgt cca gtg aca att atg ttg act gtc agt gaa tgt      144
 Leu Lys Ile Met Cys Pro Val Thr Ile Met Leu Thr Val Ser Glu Cys
          35                  40                  45

 cca agt cag tgt gtg ttc aag ggg cag cca gct gac att tgc ctg caa      192
 Pro Ser Gln Cys Val Phe Lys Gly Gln Pro Ala Asp Ile Cys Leu Gln
      50                  55                  60

 tgt gga tgt ggc agc aca tcc tgc cag tgt ggc aga ggg ggg acc ctg      240
 Cys Gly Cys Gly Ser Thr Ser Cys Gln Cys Gly Arg Gly Gly Thr Leu
  65                  70                  75                  80

 gcc tca gca tgg gaa tgt tcc ctg gaa ggc tca gtc ctt tca tca ttc      288
 Ala Ser Ala Trp Glu Cys Ser Leu Glu Gly Ser Val Leu Ser Ser Phe
                  85                  90                  95

 agg tta tca tgg cgt cat cat tcg tgt aat gta ctg tga                  327
 Arg Leu Ser Trp Arg His His Ser Cys Asn Val Leu 
             100                 105





      <210> 1025
      <211> 360
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(360)

      <400> 1025
  atg ccc agc cta ggc agt ttc ttt atc tcc cta tca aac caa tcc tgt      48
  Met Pro Ser Leu Gly Ser Phe Phe Ile Ser Leu Ser Asn Gln Ser Cys
    1               5                  10                  15

 cta ccc atg cat aaa aag ata ata cta tcc tcc tac ctg tct gag caa       96
 Leu Pro Met His Lys Lys Ile Ile Leu Ser Ser Tyr Leu Ser Glu Gln
              20                  25                  30

 ctc cag ctt ctt cag ttc ttc att tac ttg ctg ctg gtg tct tgg cta      144
 Leu Gln Leu Leu Gln Phe Phe Ile Tyr Leu Leu Leu Val Ser Trp Leu
          35                  40                  45

 gca atc tgg gag gcc aga tcc act cac gcc aca aac act atg agc act      192
 Ala Ile Trp Glu Ala Arg Ser Thr His Ala Thr Asn Thr Met Ser Thr
      50                  55                  60

 gat acc cac ctc aca ggg ctc ctt aag gcc atg acc aag gtt tgc aag      240
 Asp Thr His Leu Thr Gly Leu Leu Lys Ala Met Thr Lys Val Cys Lys
  65                  70                  75                  80

 aac tcg gaa cag tct agc ggg aag tat gaa gct cca atg gag gct gag      288
 Asn Ser Glu Gln Ser Ser Gly Lys Tyr Glu Ala Pro Met Glu Ala Glu
                  85                  90                  95

 aag gca ggc cca gca gca gac gag gag aaa gaa cca gag gcc ctg aca      336
 Lys Ala Gly Pro Ala Ala Asp Glu Glu Lys Glu Pro Glu Ala Leu Thr
             100                 105                 110

 gga ccc cag tac cta cac aac taa                                      360
 Gly Pro Gln Tyr Leu His Asn 
         115





      <210> 1026
      <211> 597
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(597)

      <400> 1026
  atg agg aag ctt agc tcc cct gtg ctg ctg ggc tcc ttg gca ggc gtg      48
  Met Arg Lys Leu Ser Ser Pro Val Leu Leu Gly Ser Leu Ala Gly Val
    1               5                  10                  15

 gct cac ttg ccc ttg gtc tct tgg gcc tgg agc tgc cca ata ctc agg       96
 Ala His Leu Pro Leu Val Ser Trp Ala Trp Ser Cys Pro Ile Leu Arg
              20                  25                  30

 gac acc aac acc cgc tca ggc cag agt gtg gac aaa gcc cca gcc gca      144
 Asp Thr Asn Thr Arg Ser Gly Gln Ser Val Asp Lys Ala Pro Ala Ala
          35                  40                  45

 aac gat ccc acc tca ggc act aac gag tgg ctg gag ctg ctg ttc ccc      192
 Asn Asp Pro Thr Ser Gly Thr Asn Glu Trp Leu Glu Leu Leu Phe Pro
      50                  55                  60

 tct ccc cac aag gga tgg aaa gga cgg tct cca gag ctg ccc ttc ctg      240
 Ser Pro His Lys Gly Trp Lys Gly Arg Ser Pro Glu Leu Pro Phe Leu
  65                  70                  75                  80

 cag agc tgg tgt gag gac agg gag gca ctg aac act gac acg gga gtt      288
 Gln Ser Trp Cys Glu Asp Arg Glu Ala Leu Asn Thr Asp Thr Gly Val
                  85                  90                  95

 tct atg agc atg gat tac ttg tgc aaa tca aaa caa aac aaa cgg atg      336
 Ser Met Ser Met Asp Tyr Leu Cys Lys Ser Lys Gln Asn Lys Arg Met
             100                 105                 110

 gct cat ccg gca aac atc cat ggg cag ggt tgg tgt cgg gtg ctg gac      384
 Ala His Pro Ala Asn Ile His Gly Gln Gly Trp Cys Arg Val Leu Asp
         115                 120                 125

 gca gag atg aat gga ggg ctc tgg cct cag cgg ctc aca gtc tgg cat      432
 Ala Glu Met Asn Gly Gly Leu Trp Pro Gln Arg Leu Thr Val Trp His
     130                 135                 140

 gac tcg gcc cag gag gag atg ggg cag atg ctg cag aag gag ggt tca      480
 Asp Ser Ala Gln Glu Glu Met Gly Gln Met Leu Gln Lys Glu Gly Ser
 145                 150                 155                 160

 tgc ccc tcc act gct gcc cat gac tcg agg gtc agg gaa gaa gag gaa      528
 Cys Pro Ser Thr Ala Ala His Asp Ser Arg Val Arg Glu Glu Glu Glu
                 165                 170                 175

 gtg cca gac cgg gga aga gcc att gaa ggc ctc tcc aat gcc cag tgc      576
 Val Pro Asp Arg Gly Arg Ala Ile Glu Gly Leu Ser Asn Ala Gln Cys
             180                 185                 190

 aaa gct cgg agc cag gtt tag                                          597
 Lys Ala Arg Ser Gln Val 
         195





      <210> 1027
      <211> 417
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(417)

      <400> 1027
  atg agg gcc tcg gtg cta gtc tcc ttc aag gcc acc gtg gtc agc cca      48
  Met Arg Ala Ser Val Leu Val Ser Phe Lys Ala Thr Val Val Ser Pro
    1               5                  10                  15

 ttc act ctc ggg ctc gag ggc tgc tcg ttg tcg gag agc aca atc acg       96
 Phe Thr Leu Gly Leu Glu Gly Cys Ser Leu Ser Glu Ser Thr Ile Thr
              20                  25                  30

 tca gct acg tgg tgg ctg tac ctg aac gct ggt cct agc cct gat gaa      144
 Ser Ala Thr Trp Trp Leu Tyr Leu Asn Ala Gly Pro Ser Pro Asp Glu
          35                  40                  45

 gca gct tct cac cag aga cct ggg cgt gga cag aaa ggt ccc att ccc      192
 Ala Ala Ser His Gln Arg Pro Gly Arg Gly Gln Lys Gly Pro Ile Pro
      50                  55                  60

 acc tcg gag aag gaa atg gag ttg ttt gcc ggg agc tgc ccc aag gct      240
 Thr Ser Glu Lys Glu Met Glu Leu Phe Ala Gly Ser Cys Pro Lys Ala
  65                  70                  75                  80

 gtc att tgg tgg ggc ggg agc atc ctg ctg tca gat cac atg ctg cct      288
 Val Ile Trp Trp Gly Gly Ser Ile Leu Leu Ser Asp His Met Leu Pro
                  85                  90                  95

 ctt cag agc cag ccg ccc aca tcc agc agc ccc caa aac cca gat ggc      336
 Leu Gln Ser Gln Pro Pro Thr Ser Ser Ser Pro Gln Asn Pro Asp Gly
             100                 105                 110

 agc agc acc acg gcc tcc aga ggc aag atg gat gct ctg aca gga tgc      384
 Ser Ser Thr Thr Ala Ser Arg Gly Lys Met Asp Ala Leu Thr Gly Cys
         115                 120                 125

 aac ctt gaa ggg gat agg agc atg cag gag tga                          417
 Asn Leu Glu Gly Asp Arg Ser Met Gln Glu 
     130                 135





      <210> 1028
      <211> 168
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(168)

      <400> 1028
  atg gct gca ctg ctg tcg ttg atg gca ggg atg gcc act gtg ctg gca      48
  Met Ala Ala Leu Leu Ser Leu Met Ala Gly Met Ala Thr Val Leu Ala
    1               5                  10                  15

 ctc agg cag gat cca cca gag ttc acg gtg tgg ttc ctg ctg ttc ctg       96
 Leu Arg Gln Asp Pro Pro Glu Phe Thr Val Trp Phe Leu Leu Phe Leu
              20                  25                  30

 gac ctc acg acg gag ctt gga gcc tgg gag gaa tgg cca cag ttt tca      144
 Asp Leu Thr Thr Glu Leu Gly Ala Trp Glu Glu Trp Pro Gln Phe Ser
          35                  40                  45

 cca aat gct caa gag gat gct tga                                      168
 Pro Asn Ala Gln Glu Asp Ala 
      50                  55





      <210> 1029
      <211> 912
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(912)

      <400> 1029
  atg gcc gca ctg gca atg gcc gca ctg gcg atg gcc aca ctg acg atg      48
  Met Ala Ala Leu Ala Met Ala Ala Leu Ala Met Ala Thr Leu Thr Met
    1               5                  10                  15

 gcc gca ctg atg atg gca ttg ggt ccc acg tgc acc gac gtg ggg acg       96
 Ala Ala Leu Met Met Ala Leu Gly Pro Thr Cys Thr Asp Val Gly Thr
              20                  25                  30

 ctc act att gca gca ccg aca agg ggc acc aac acg ggg atg ttc aca      144
 Leu Thr Ile Ala Ala Pro Thr Arg Gly Thr Asn Thr Gly Met Phe Thr
          35                  40                  45

 att cca gca ccg aca tgg gga cgc tca cta ttc cag cac cga cac ggg      192
 Ile Pro Ala Pro Thr Trp Gly Arg Ser Leu Phe Gln His Arg His Gly
      50                  55                  60

 gat gct cac tat tcc agc acc gac gtg ggg acg ctc gct att tca gca      240
 Asp Ala His Tyr Ser Ser Thr Asp Val Gly Thr Leu Ala Ile Ser Ala
  65                  70                  75                  80

 ccg aca agg ggc acc gac acg ggg acg ctc act att cca gca ccg aca      288
 Pro Thr Arg Gly Thr Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr
                  85                  90                  95

 agg ggc acc gac acg ggg aca ctc act att cca gca ccg aca cgg gga      336
 Arg Gly Thr Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr Arg Gly
             100                 105                 110

 cgt tca cta ttt cag cac cga cac ggg gac gat cac tat tcc agc acc      384
 Arg Ser Leu Phe Gln His Arg His Gly Asp Asp His Tyr Ser Ser Thr
         115                 120                 125

 gac acg ggg acg ttc act att tca gca ccg aca cgg gga cga tca cta      432
 Asp Thr Gly Thr Phe Thr Ile Ser Ala Pro Thr Arg Gly Arg Ser Leu
     130                 135                 140

 ttc cag cac cga cac ggg gac gct cac tat tcc agc acc gac aag ggg      480
 Phe Gln His Arg His Gly Asp Ala His Tyr Ser Ser Thr Asp Lys Gly
 145                 150                 155                 160

 cac cga cat ggg gat gct cac tat tcc agc act gac aag ggg cac cga      528
 His Arg His Gly Asp Ala His Tyr Ser Ser Thr Asp Lys Gly His Arg
                 165                 170                 175

 tac ggg gac gcc cac tct acc agc acc gac acg ggg acg ctc act att      576
 Tyr Gly Asp Ala His Ser Thr Ser Thr Asp Thr Gly Thr Leu Thr Ile
             180                 185                 190

 gca gca ccg aca agg ggc acc gac atg ggg acg ctc act att cca gca      624
 Ala Ala Pro Thr Arg Gly Thr Asp Met Gly Thr Leu Thr Ile Pro Ala
         195                 200                 205

 ccg aca cgg ggc acc gac atg ggg acg ctc act att cca gca ccg aca      672
 Pro Thr Arg Gly Thr Asp Met Gly Thr Leu Thr Ile Pro Ala Pro Thr
     210                 215                 220

 cgg ggt cgc tca cta ttc cag cac cga cac ggg gac act cac tat tcc      720
 Arg Gly Arg Ser Leu Phe Gln His Arg His Gly Asp Thr His Tyr Ser
 225                 230                 235                 240

 agc acc gac acg ggg cac cga cac ggg gac gct cac tat tcc agc acc      768
 Ser Thr Asp Thr Gly His Arg His Gly Asp Ala His Tyr Ser Ser Thr
                 245                 250                 255

 gac acg ggg acg ctc act att cca gca ccg aca cgg ggc acc gac acg      816
 Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr Arg Gly Thr Asp Thr
             260                 265                 270

 ggg acg ctc act gtt cca gca ccg ata cgg ggc acc aac atg agg acg      864
 Gly Thr Leu Thr Val Pro Ala Pro Ile Arg Gly Thr Asn Met Arg Thr
         275                 280                 285

 ctc act att gca gca ccg ata cag gga tgc tca cta ttc cag cgc taa      912
 Leu Thr Ile Ala Ala Pro Ile Gln Gly Cys Ser Leu Phe Gln Arg 
     290                 295                 300





      <210> 1030
      <211> 612
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(612)

      <400> 1030
  atg gct gtg aaa ggg gag ctt ctc ctg gga gtt gcg gaa gcc gct gtt      48
  Met Ala Val Lys Gly Glu Leu Leu Leu Gly Val Ala Glu Ala Ala Val
    1               5                  10                  15

 gtg cag cat cca gga ctc gcg gta ctg ctc ctt gag ctg ctg cat ctt       96
 Val Gln His Pro Gly Leu Ala Val Leu Leu Leu Glu Leu Leu His Leu
              20                  25                  30

 gtg ggc gcg cac gat gct cag gca ctc cag ctc gat gct gcg cag ctc      144
 Val Gly Ala His Asp Ala Gln Ala Leu Gln Leu Asp Ala Ala Gln Leu
          35                  40                  45

 ttc gtt cag cag ctc cag ctc ctt gtc cac gct ctc agg gtc act ctt      192
 Phe Val Gln Gln Leu Gln Leu Leu Val His Ala Leu Arg Val Thr Leu
      50                  55                  60

 gcc ggc gtc cag ggg gcc gct agg gta gta cag gcc gta agg ggt ggc      240
 Ala Gly Val Gln Gly Ala Ala Arg Val Val Gln Ala Val Arg Gly Gly
  65                  70                  75                  80

 gct ctt cac ctg gca ctt gag ctc cag gag ctc gcg gaa gcg ctc gca      288
 Ala Leu His Leu Ala Leu Glu Leu Gln Glu Leu Ala Glu Ala Leu Ala
                  85                  90                  95

 ctc gtc cac cgg gat ccc cag gta gtc ggc gtc cgt gca gtc ggc cga      336
 Leu Val His Arg Asp Pro Gln Val Val Gly Val Arg Ala Val Gly Arg
             100                 105                 110

 aat gaa aga ctc gtt gct gaa ggg cag gtc gcc gct gcc caa ggt gtc      384
 Asn Glu Arg Leu Val Ala Glu Gly Gln Val Ala Ala Ala Gln Gly Val
         115                 120                 125

 ctg gct gca ggt gag ctt cct ctg ccc cgc cag cgg gtt gga gga tgc      432
 Leu Ala Ala Gly Glu Leu Pro Leu Pro Arg Gln Arg Val Gly Gly Cys
     130                 135                 140

 ggt ggc gtc gtc gcc att gtt ctc ttg ctc cga gct ctc gtc att acg      480
 Gly Gly Val Val Ala Ile Val Leu Leu Leu Arg Ala Leu Val Ile Thr
 145                 150                 155                 160

 ggt gct ctc gtc ggt ccg ccc cac acc gct gtc ctt ctc gtg ctg gtt      528
 Gly Ala Leu Val Gly Pro Pro His Thr Ala Val Leu Leu Val Leu Val
                 165                 170                 175

 gga caa gat ggt ggc tgt atc tgt ggt ccc acc gtc ttc gtc gtg ctt      576
 Gly Gln Asp Gly Gly Cys Ile Cys Gly Pro Thr Val Phe Val Val Leu
             180                 185                 190

 ctt ctg cat aaa cac aag aac aaa ggg tca cag tga                      612
 Leu Leu His Lys His Lys Asn Lys Gly Ser Gln 
         195                 200





      <210> 1031
      <211> 126
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(126)

      <400> 1031
  atg ctt aag gaa ctg ttg ctt ctg ctg ctc tat caa ctg ggc ccg ctg      48
  Met Leu Lys Glu Leu Leu Leu Leu Leu Leu Tyr Gln Leu Gly Pro Leu
    1               5                  10                  15

 atc aat gag cat ctg ctt cat gat ggc tgc ttg ggg ctg gct gcc cag       96
 Ile Asn Glu His Leu Leu His Asp Gly Cys Leu Gly Leu Ala Ala Gln
              20                  25                  30

 gaa gcc ggg gcc tgc ggg act ggc tcc tga                              126
 Glu Ala Gly Ala Cys Gly Thr Gly Ser 
          35                  40





      <210> 1032
      <211> 258
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(258)

      <400> 1032
  atg aac aga gac ggc acg acc tgg ttg cag cgg ctg agg tgg gtg atg      48
  Met Asn Arg Asp Gly Thr Thr Trp Leu Gln Arg Leu Arg Trp Val Met
    1               5                  10                  15

 ctg ccc cac ctg cag atg cta acc ctg tgc atc caa agc ccc aga aaa       96
 Leu Pro His Leu Gln Met Leu Thr Leu Cys Ile Gln Ser Pro Arg Lys
              20                  25                  30

 cca cct gaa agt tac tac aag gaa gaa ctc aga agc cat gaa agt tac      144
 Pro Pro Glu Ser Tyr Tyr Lys Glu Glu Leu Arg Ser His Glu Ser Tyr
          35                  40                  45

 tac aag gaa gag aac tca gaa gcc atg aaa gtt act aca agg aag aga      192
 Tyr Lys Glu Glu Asn Ser Glu Ala Met Lys Val Thr Thr Arg Lys Arg
      50                  55                  60

 act cag aag cca tgg ggc cca cag tta cca cgc aga gac caa gct gcc      240
 Thr Gln Lys Pro Trp Gly Pro Gln Leu Pro Arg Arg Asp Gln Ala Ala
  65                  70                  75                  80

 tgc tgc tgg atg ctc tga                                              258
 Cys Cys Trp Met Leu 
                  85





      <210> 1033
      <211> 546
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(546)

      <400> 1033
  atg cag att ctg att cag tgg ctc tgg gag tct act cgt tcc gct ctc      48
  Met Gln Ile Leu Ile Gln Trp Leu Trp Glu Ser Thr Arg Ser Ala Leu
    1               5                  10                  15

 gca tgc tgc aag tct act cta aag gat ccc cat cag gcg ccc cgg agg       96
 Ala Cys Cys Lys Ser Thr Leu Lys Asp Pro His Gln Ala Pro Arg Arg
              20                  25                  30

 agg tct gtc aca cct gct gcc aag cgc cac caa tgc ccc ttc ccg ggc      144
 Arg Ser Val Thr Pro Ala Ala Lys Arg His Gln Cys Pro Phe Pro Gly
          35                  40                  45

 tgc acc aaa gcc tat tac aag tcg tcg cac ctc aag tcc cac cag cgc      192
 Cys Thr Lys Ala Tyr Tyr Lys Ser Ser His Leu Lys Ser His Gln Arg
      50                  55                  60

 acc cac acg ggt gag cgc cct ttc tcc tgc gac tgg ctc gac tgc gac      240
 Thr His Thr Gly Glu Arg Pro Phe Ser Cys Asp Trp Leu Asp Cys Asp
  65                  70                  75                  80

 aag aag ttt acg cgt tcc gac gag ctg gcc cgc cac tac agg acg cac      288
 Lys Lys Phe Thr Arg Ser Asp Glu Leu Ala Arg His Tyr Arg Thr His
                  85                  90                  95

 acg ggc gag aaa cgc ttc tcc tgc ccc ctc tgc ccc aag cag ttc tcc      336
 Thr Gly Glu Lys Arg Phe Ser Cys Pro Leu Cys Pro Lys Gln Phe Ser
             100                 105                 110

 cgg agc gac cac ctg acc aag cat gct cgc cgc cac cca acc tat cat      384
 Arg Ser Asp His Leu Thr Lys His Ala Arg Arg His Pro Thr Tyr His
         115                 120                 125

 cca gat atg atc gag tac cgg gga cgt cgt cga act ccc cgc atc gac      432
 Pro Asp Met Ile Glu Tyr Arg Gly Arg Arg Arg Thr Pro Arg Ile Asp
     130                 135                 140

 ccg cca ctc acc agc gag acg gca act tcc cac cat cat acc cga agt      480
 Pro Pro Leu Thr Ser Glu Thr Ala Thr Ser His His His Thr Arg Ser
 145                 150                 155                 160

 gtg ttc tac cta cag att aga gta aaa cct gat gtc cag gct aca ttt      528
 Val Phe Tyr Leu Gln Ile Arg Val Lys Pro Asp Val Gln Ala Thr Phe
                 165                 170                 175

 ttt gct ctt aat att taa                                              546
 Phe Ala Leu Asn Ile 
             180





      <210> 1034
      <211> 132
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(132)

      <400> 1034
  atg gtg atc cca ctc ttc ttt gtg ttt cag cca cca cta ggg cag ctc      48
  Met Val Ile Pro Leu Phe Phe Val Phe Gln Pro Pro Leu Gly Gln Leu
    1               5                  10                  15

 ctg gca caa ctc ttg tcc ctg gca gtt cca ata cag ggg cca cag ctt       96
 Leu Ala Gln Leu Leu Ser Leu Ala Val Pro Ile Gln Gly Pro Gln Leu
              20                  25                  30

 ccc cag gtg gaa gtg caa cga caa gag gta gaa taa                      132
 Pro Gln Val Glu Val Gln Arg Gln Glu Val Glu 
          35                  40





      <210> 1035
      <211> 768
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(768)

      <400> 1035
  atg cgc ccc cga gcc cca gcc tgc gcc gcc gcg gcg ctc ggg ctc tgc      48
  Met Arg Pro Arg Ala Pro Ala Cys Ala Ala Ala Ala Leu Gly Leu Cys
    1               5                  10                  15

 agc ctt ctg ctg ctg ctc gcg ccc ggg cac gcg tgc ccc gcg ggc tgc       96
 Ser Leu Leu Leu Leu Leu Ala Pro Gly His Ala Cys Pro Ala Gly Cys
              20                  25                  30

 gcc tgc acc gac ccg cac acc gtg gac tgc cgc gac cgc ggg ctg ccc      144
 Ala Cys Thr Asp Pro His Thr Val Asp Cys Arg Asp Arg Gly Leu Pro
          35                  40                  45

 agc gtg cca gac cct ttc ccc ctg gac gtg cgc aag ctg ctg gtg gcc      192
 Ser Val Pro Asp Pro Phe Pro Leu Asp Val Arg Lys Leu Leu Val Ala
      50                  55                  60

 ggc aac cgc atc cag cgg atc ccc gag gac ttc ttc atc ttc tac ggc      240
 Gly Asn Arg Ile Gln Arg Ile Pro Glu Asp Phe Phe Ile Phe Tyr Gly
  65                  70                  75                  80

 gac ctg gtc tac ctg gac ttc agg aac aac tcg ctg cgc tcg ctg gag      288
 Asp Leu Val Tyr Leu Asp Phe Arg Asn Asn Ser Leu Arg Ser Leu Glu
                  85                  90                  95

 gag ggc acg ttc agc ggc tcg gcc aag ctc gtg ttc ctc gac ctc agc      336
 Glu Gly Thr Phe Ser Gly Ser Ala Lys Leu Val Phe Leu Asp Leu Ser
             100                 105                 110

 tac aac aac ttg acc cag ctg ggc gcc ggc gcc ttc cgc tcg gcc ggg      384
 Tyr Asn Asn Leu Thr Gln Leu Gly Ala Gly Ala Phe Arg Ser Ala Gly
         115                 120                 125

 agg ctg gtg aag ctt agc ctg gct aac aac aac ctg gtg ggc gtg cac      432
 Arg Leu Val Lys Leu Ser Leu Ala Asn Asn Asn Leu Val Gly Val His
     130                 135                 140

 gag gac gcc ttc gag acc ctg gag tcg ctg cag gtg ctg gag ctc aac      480
 Glu Asp Ala Phe Glu Thr Leu Glu Ser Leu Gln Val Leu Glu Leu Asn
 145                 150                 155                 160

 gac aac aac ctg cgc agc ctc agc gtg gcc gcc ctg gcc gcg ctg ccc      528
 Asp Asn Asn Leu Arg Ser Leu Ser Val Ala Ala Leu Ala Ala Leu Pro
                 165                 170                 175

 gcg ctg cgc tcc ctg cgt ctg gac ggg aac ccc tgg ctg tgc gac tgt      576
 Ala Leu Arg Ser Leu Arg Leu Asp Gly Asn Pro Trp Leu Cys Asp Cys
             180                 185                 190

 gac ttc gcc cac ctc ttc tcc tgg atc cag gag aac gca tcc aaa ctg      624
 Asp Phe Ala His Leu Phe Ser Trp Ile Gln Glu Asn Ala Ser Lys Leu
         195                 200                 205

 ccc aaa gga ctg gcg ggt gtg gat tac tta tgc gtc cct ggt aag cgg      672
 Pro Lys Gly Leu Ala Gly Val Asp Tyr Leu Cys Val Pro Gly Lys Arg
     210                 215                 220

 aat gca gcc tac tct atg gga aac ggc cgt att ctc agt acc gtg cac      720
 Asn Ala Ala Tyr Ser Met Gly Asn Gly Arg Ile Leu Ser Thr Val His
 225                 230                 235                 240

 ggg gag tca gcc agt tcc aag ggc tct cca gca gct tcc cga gcc taa      768
 Gly Glu Ser Ala Ser Ser Lys Gly Ser Pro Ala Ala Ser Arg Ala 
                 245                 250                 255





      <210> 1036
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(264)

      <400> 1036
  atg ggc atc tac cag atg tac ttg tgc ttc ctg ctg gcc gtg ctg ctg      48
  Met Gly Ile Tyr Gln Met Tyr Leu Cys Phe Leu Leu Ala Val Leu Leu
    1               5                  10                  15

 cag ctc tac gtg gcc acg gag gcc atc ctc att gca ctg gtt ggg gcc       96
 Gln Leu Tyr Val Ala Thr Glu Ala Ile Leu Ile Ala Leu Val Gly Ala
              20                  25                  30

 acg cca tcc tac cac tgg gac ctg gca gag ctc ctg cca aat cag agc      144
 Thr Pro Ser Tyr His Trp Asp Leu Ala Glu Leu Leu Pro Asn Gln Ser
          35                  40                  45

 cac ggt aac cag tca gct ggt gaa gac cag gcc ttt ggg gac tgg ctc      192
 His Gly Asn Gln Ser Ala Gly Glu Asp Gln Ala Phe Gly Asp Trp Leu
      50                  55                  60

 ctg aca gcc aac ggc agt gag atc cat aag cac gtg cat ttc agc agc      240
 Leu Thr Ala Asn Gly Ser Glu Ile His Lys His Val His Phe Ser Ser
  65                  70                  75                  80

 agc ttc acc tcc atc gcc tcg gag                                      264
 Ser Phe Thr Ser Ile Ala Ser Glu 
                  85





      <210> 1037
      <211> 204
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(204)

      <400> 1037
  atg ccc ctg act gct gcg gcc tcc act gtg ttt cga atg acg aat ttc      48
  Met Pro Leu Thr Ala Ala Ala Ser Thr Val Phe Arg Met Thr Asn Phe
    1               5                  10                  15

 tta atg gcc ttg tcc ttg ggc atg cat cgg gca cat gct cag tgc acg       96
 Leu Met Ala Leu Ser Leu Gly Met His Arg Ala His Ala Gln Cys Thr
              20                  25                  30

 aaa gtt ttc cac tgt ttt tgg aac ttt gtc ggc aaa cag ctc gaa gga      144
 Lys Val Phe His Cys Phe Trp Asn Phe Val Gly Lys Gln Leu Glu Gly
          35                  40                  45

 gct gca tgg gcc aaa gga gtt acc atc aac aat gat gtc aaa aga aca      192
 Ala Ala Trp Ala Lys Gly Val Thr Ile Asn Asn Asp Val Lys Arg Thr
      50                  55                  60

 cag tgg cgt tga                                                      204
 Gln Trp Arg 
  65





      <210> 1038
      <211> 387
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(387)

      <400> 1038
  atg gcc ttt gga ggg cag ttg ttt gca tat gcc tca cgg agt att cat      48
  Met Ala Phe Gly Gly Gln Leu Phe Ala Tyr Ala Ser Arg Ser Ile His
    1               5                  10                  15

 aca gct ttc ctg ttc tgc tcc gag cca ttg gct tac tac cgc att cag       96
 Thr Ala Phe Leu Phe Cys Ser Glu Pro Leu Ala Tyr Tyr Arg Ile Gln
              20                  25                  30

 ttg gtg aag act agg gaa aga ctg gac aaa ttt gcc agc ata aga att      144
 Leu Val Lys Thr Arg Glu Arg Leu Asp Lys Phe Ala Ser Ile Arg Ile
          35                  40                  45

 cca ggg agc aag aaa gag aga cct cca ctt ccc aac ctg aag act gca      192
 Pro Gly Ser Lys Lys Glu Arg Pro Pro Leu Pro Asn Leu Lys Thr Ala
      50                  55                  60

 ttt gca agc agt gat tgc tca gca gca cct tta gag atg atg gag aac      240
 Phe Ala Ser Ser Asp Cys Ser Ala Ala Pro Leu Glu Met Met Glu Asn
  65                  70                  75                  80

 ttt cca aag cca ctg tca gag aat gaa ctc tta gaa ctt ttt gaa aaa      288
 Phe Pro Lys Pro Leu Ser Glu Asn Glu Leu Leu Glu Leu Phe Glu Lys
                  85                  90                  95

 atg atg aag tcc cca ctg aag tca tac ttg gga gtc ata gtt gat ctc      336
 Met Met Lys Ser Pro Leu Lys Ser Tyr Leu Gly Val Ile Val Asp Leu
             100                 105                 110

 att aag gca tca gtc aca tcc att tac ttc tct atc ttc att agc tct      384
 Ile Lys Ala Ser Val Thr Ser Ile Tyr Phe Ser Ile Phe Ile Ser Ser
         115                 120                 125

 taa                                                                  387
 






      <210> 1039
      <211> 234
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(234)

      <400> 1039
  atg tcc gag ttt ctc ctc gcc tta ctc act ctc tcg gga tta ttg ccg      48
  Met Ser Glu Phe Leu Leu Ala Leu Leu Thr Leu Ser Gly Leu Leu Pro
    1               5                  10                  15

 att gcc agg gtg ctg acc gtg gga gcc gac cga ggt tat gaa gag cat       96
 Ile Ala Arg Val Leu Thr Val Gly Ala Asp Arg Gly Tyr Glu Glu His
              20                  25                  30

 cta aac aga gtg cca aaa agg cag ctt gga gta atc aac cct ttt aaa      144
 Leu Asn Arg Val Pro Lys Arg Gln Leu Gly Val Ile Asn Pro Phe Lys
          35                  40                  45

 cac tat tta att tat att gct gga cct gca gca ttg tgg aag aat ata      192
 His Tyr Leu Ile Tyr Ile Ala Gly Pro Ala Ala Leu Trp Lys Asn Ile
      50                  55                  60

 ctt tac ttc aac cag aga aat tac ctt gga aat gct aca tga              234
 Leu Tyr Phe Asn Gln Arg Asn Tyr Leu Gly Asn Ala Thr 
  65                  70                  75





      <210> 1040
      <211> 450
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(450)

      <400> 1040
  atg aca ttc ctg att ctg agt att gct cca gta ctt gcc gtg aca gga      48
  Met Thr Phe Leu Ile Leu Ser Ile Ala Pro Val Leu Ala Val Thr Gly
    1               5                  10                  15

 atg att gaa acc gca gca atg act gga ttt gcc aac aaa gat aag caa       96
 Met Ile Glu Thr Ala Ala Met Thr Gly Phe Ala Asn Lys Asp Lys Gln
              20                  25                  30

 gaa ctt aag cat gct gga aag ata gca act gaa gct ttg gag aat ata      144
 Glu Leu Lys His Ala Gly Lys Ile Ala Thr Glu Ala Leu Glu Asn Ile
          35                  40                  45

 cgt act ata gtg tca tta aca agg gaa aaa gcc ttc gag caa atg tat      192
 Arg Thr Ile Val Ser Leu Thr Arg Glu Lys Ala Phe Glu Gln Met Tyr
      50                  55                  60

 gaa gag atg ctt cag act caa cac aga aat acc tcg aag aaa gca cag      240
 Glu Glu Met Leu Gln Thr Gln His Arg Asn Thr Ser Lys Lys Ala Gln
  65                  70                  75                  80

 att att gga agc tgt tat gca ttc agc cat gcc ttt ata tat ttt gcc      288
 Ile Ile Gly Ser Cys Tyr Ala Phe Ser His Ala Phe Ile Tyr Phe Ala
                  85                  90                  95

 tat gcg gca ggg ttt cga ttt gga gcc tat tta att caa gct gga cga      336
 Tyr Ala Ala Gly Phe Arg Phe Gly Ala Tyr Leu Ile Gln Ala Gly Arg
             100                 105                 110

 atg acc cca gag ggc atg ttc ata gat tat ccg gaa gag aca gac aag      384
 Met Thr Pro Glu Gly Met Phe Ile Asp Tyr Pro Glu Glu Thr Asp Lys
         115                 120                 125

 gac aag ata aga agg cta aat caa cca ctg aag gga cct aaa gaa gag      432
 Asp Lys Ile Arg Arg Leu Asn Gln Pro Leu Lys Gly Pro Lys Glu Glu
     130                 135                 140

 aaa tca aag gac agt tga                                              450
 Lys Ser Lys Asp Ser 
 145





      <210> 1041
      <211> 210
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> CDS
      <222> (1)..(210)

      <400> 1041
  atg agt cag tac aaa gtc acc aca ata gta cca tgc tcc atg ttt gct      48
  Met Ser Gln Tyr Lys Val Thr Thr Ile Val Pro Cys Ser Met Phe Ala
    1               5                  10                  15

 atc acc ctt gtt aca aac acc tca gtc tcc gtt gag cct atc atc aga       96
 Ile Thr Leu Val Thr Asn Thr Ser Val Ser Val Glu Pro Ile Ile Arg
              20                  25                  30

 cag tta aca agg aag gtg ggt gtc atg aac agg aca agt cag tca ctc      144
 Gln Leu Thr Arg Lys Val Gly Val Met Asn Arg Thr Ser Gln Ser Leu
          35                  40                  45

 cat ctt ctg ggt cgc act gca ttc tct tca tac ctc aat gat ggc atg      192
 His Leu Leu Gly Arg Thr Ala Phe Ser Ser Tyr Leu Asn Asp Gly Met
      50                  55                  60

 gaa gat att gtg gtc taa                                              210
 Glu Asp Ile Val Val 
  65



      <210> 1042
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1042
 Met Pro Ala Val Ser Arg Lys Gln Leu Arg Ser Ile Phe Ile Leu Ile
   1               5                  10                  15    
 Pro Ile Leu Ile Leu Met Ala Val Arg Ser Thr Ser Leu Glu Trp Gly
              20                  25                  30        
 Met Arg Gln Pro Ser Lys Lys Arg Ser Leu Glu Lys Leu Arg Leu Val
          35                  40                  45            
 Arg Ala Leu Gly Trp Ser Leu Gly Arg Phe Thr Arg Leu Gln Arg Glu
      50                  55                  60                
 Glu Leu Val Leu Ser Arg Thr Arg Val Val Thr Trp Gly Phe Asn Leu
  65                  70                  75                  80
 Ser Ser Gly Cys Ile Lys Ala Phe Pro His Lys Arg Thr Asp Val Val
                  85                  90                  95    
 Thr Val Ala His His Ala Thr Val Tyr Phe His Gln Glu Lys Lys Ala
             100                 105                 110        
 Phe His Gly Ser Leu Thr Glu Asp Met Lys Pro Phe Thr Ile
         115                 120                 125    



      <210> 1043
      <211> 194
      <212> PRT
      <213> Homo sapiens


      <400> 1043
 Met Glu Thr Trp Ser Gly Pro Ala Gly Ala Gln Gly Tyr Ala Leu Met
   1               5                  10                  15    
 Cys Val Leu Met Trp Leu Glu Ser Glu Gly Val Arg Lys Gly Pro Ser
              20                  25                  30        
 Gly Ser Cys Leu Arg Ser Cys Arg Leu Thr Phe Gly Gly Ala Glu Lys
          35                  40                  45            
 Ala Ala Trp Lys Ser Asp Leu Gly Thr Ser Leu Gly Ile Ile Arg Ala
      50                  55                  60                
 His Ser Glu Asp Arg Thr Glu Gln Asp Gln Arg Val Val Trp Phe Gly
  65                  70                  75                  80
 Val Ser Ala Val Gly Gly Gly Asp Gly Arg Gln Glu Thr Asp Phe Gly
                  85                  90                  95    
 Leu Asp Ser Tyr Lys Glu Leu Val Met Gly Ser Lys Ala Phe Gln Gln
             100                 105                 110        
 Arg Asp Ile Pro Ser Gly Cys Glu Val Ala Cys Cys Asp Pro Ala Arg
         115                 120                 125            
 Leu Trp Gln Glu Gln Pro Arg His Met Asp Ser Glu Glu Ser Leu Arg
     130                 135                 140                
 Ile Arg Thr His Glu Cys Leu Leu Ala Phe Gln Ile Gln Lys Ser Gly
 145                 150                 155                 160
 His Phe Phe His Arg Asn Ser Leu Ser Pro Arg Ser Leu Val Tyr Glu
                 165                 170                 175    
 Ser Glu Phe Ser Thr Ile Glu Pro Ser Leu Asp Met Tyr Asp Glu Asn
             180                 185                 190        
 Lys Thr
        



      <210> 1044
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1044
 Met Ala Gly Ser Met Leu Leu Lys Ala Leu Leu Asp Val Thr Leu Leu
   1               5                  10                  15    
 Ser Thr Ala Ser Ile Thr Gly Ala Leu Gly Leu Asn Thr Ser Ala Ile
              20                  25                  30        
 Ser Pro Phe Val Ser Ser Met Asp Thr Val Asn Asn Gly Leu Ser Thr
          35                  40                  45            
 Pro Ala Leu Cys Gln Ser Gln Gly Val Gly Trp Gly Asp Thr Glu Glu
      50                  55                  60                
 Asn Ile Phe Leu Leu Asp Ala Cys Cys Ala Asn Ser Pro Leu
  65                  70                  75            



      <210> 1045
      <211> 254
      <212> PRT
      <213> Homo sapiens


      <400> 1045
 Met Ser Leu Leu Pro Ile Tyr Thr Gln Leu Leu Ser Leu Ser Ser Ser
   1               5                  10                  15    
 Ala Ser Gly Glu Val Ile Tyr Ser Gly Ser Gly Thr Val Tyr Tyr Gly
              20                  25                  30        
 Arg Ile Arg Ser Trp Glu Glu Gly Ile Leu Asn Val Pro Gly Leu Val
          35                  40                  45            
 Ser Ser Leu Ser His Pro Ala Asn Gly Cys Thr Leu Ser Met Asn Cys
      50                  55                  60                
 Cys Val Met Phe Thr Arg Arg Tyr Gly Val Lys Gly Gly Leu Asp Gly
  65                  70                  75                  80
 Asn Gly Ser Tyr Gln Val Glu Arg Pro Cys Gly Leu Thr Gly Leu Glu
                  85                  90                  95    
 Asn Pro Glu Leu Asn Ala Gly Leu Asn Ser Ser Val Ser Asp Ala Thr
             100                 105                 110        
 Glu Ile Gln Asp Lys Ile Lys Phe Leu Ala Ser Leu Trp Leu Leu Cys
         115                 120                 125            
 Gly Ser Pro Ser Cys Cys Trp Gly Leu Leu Leu Leu Ser Phe His Pro
     130                 135                 140                
 Met Gln Ala Asp Ala Val Thr Gln Gly Ser Tyr Ser Phe Ser Phe Val
 145                 150                 155                 160
 Trp Leu Phe Ile Ser Phe Gly Val Ser Cys Asn Arg Ile Pro Ser Cys
                 165                 170                 175    
 Thr Val Asp Cys Ser Ser Ala Asp Ile Trp Gln His Pro Trp Pro Leu
             180                 185                 190        
 Leu Asn Gly Tyr Cys Phe His Asn Ile Tyr Ser Gln Tyr Glu Leu Leu
         195                 200                 205            
 Leu Tyr Gly Met Tyr Lys Arg Val His Tyr Leu Asn Thr Val Glu Lys
     210                 215                 220                
 Lys Asp Leu Leu Gly Thr Lys Ala Asp Glu Tyr Leu Ser Trp Val Ala
 225                 230                 235                 240
 Leu Asp Thr Thr Met Leu Gly Leu Trp Ser Val Ala Gln Arg
                 245                 250                



      <210> 1046
      <211> 112
      <212> PRT
      <213> Homo sapiens


      <400> 1046
 Met Pro Thr Ser Ser Cys Leu Phe Leu Met Pro Cys Leu Leu Ala Ser
   1               5                  10                  15    
 Gly Leu Ala Leu Pro Cys Cys Pro Lys Glu Phe Leu Leu Leu Leu Pro
              20                  25                  30        
 Leu Pro Pro Pro Pro His Cys Tyr Met Leu Arg Ser Pro Val His Cys
          35                  40                  45            
 Ala Thr Asp Lys Glu Gly Ile Leu Ala Pro Lys His Phe Gln Ala Ala
      50                  55                  60                
 Ala Gly Glu Ala Arg Thr Ser Thr Asp Arg Ser Gly Ala Gln Ala Gln
  65                  70                  75                  80
 Arg Ser Val Thr Pro Cys Gln Trp His Ser Val Gln Asp Ser Ser Thr
                  85                  90                  95    
 Tyr Ser Ser Val Val Val Val Val Val Ala Ala Ala Ala Glu Thr Leu
             100                 105                 110        





      <210> 1047
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1047
 Met Leu Ala Ser Pro Pro Leu Phe Ser Leu Leu Ser Ser Leu Pro Leu
   1               5                  10                  15    
 Phe Leu Pro Ser Thr Val Val Gly Asn Thr Val Asn Asp Ser Asn Gly
              20                  25                  30        
 Val Lys Gly Glu Ile Ile Lys Arg Ile Ile Lys Pro Gln Asn Trp Lys
          35                  40                  45            
 Ala Ile Tyr Ala Thr Ser Thr Tyr Gly Ala Pro Thr Ala Pro Ala Pro
      50                  55                  60                
 Pro Ile Ala Val Asn Glu Met Ser Ile Pro Leu Ala Thr Ala Thr Ser
  65                  70                  75                  80
 Gly Thr Gln Asp Leu Ala Leu Leu Pro Ala Gly Asn Cys Ser Trp Tyr
                  85                  90                  95    
 Pro Ser Ser Lys Ala Pro
             100        



      <210> 1048
      <211> 346
      <212> PRT
      <213> Homo sapiens


      <400> 1048
 Met Trp Asn Gly Met Leu Val Leu Val Ala Gln Ala Gly Gly Asp Thr
   1               5                  10                  15    
 Leu Lys Val Thr Gly His Tyr Val Lys Cys Val Phe Leu Leu Phe Val
              20                  25                  30        
 Ser His Leu Leu Ser Glu Pro Leu Ser Arg Thr Val Asp His Gly Met
          35                  40                  45            
 Phe Glu Asn Leu Asn Thr Ala Leu Thr Pro Lys Leu Gln Ala Ser Arg
      50                  55                  60                
 Ser Phe Pro His Leu Ser Lys Pro Val Ala Pro Gly Ser Ala Leu Trp
  65                  70                  75                  80
 Ala Leu Glu Asp Lys Gly Leu Ala Asn Ser Gln Leu Cys Gly Ser Ser
                  85                  90                  95    
 Gly Ser Leu Asp Leu Thr Leu Ala Gln Gly Gln Gln Arg Gly Lys Gly
             100                 105                 110        
 Thr Pro Gly Gln Leu Phe Ser Glu Pro Pro Ser Leu Arg Arg Arg Val
         115                 120                 125            
 Val Pro Val His Ile Met Met Ala His Pro Glu Thr Val Ile Gly Arg
     130                 135                 140                
 Val Gly Arg Ala Phe Ser Gln Gly Thr Gly His Leu Val Gln Glu Lys
 145                 150                 155                 160
 Glu Arg Ser Pro Leu Ala Ala Lys Ser Pro Arg Ile Arg Ile Thr Pro
                 165                 170                 175    
 Leu Gln Asp Leu Leu Val Thr Gly Arg Gln His Asn Arg Pro Leu Val
             180                 185                 190        
 Gly Asp Leu Lys Val Gly Cys Arg Asn Gln Leu Arg Leu Asp Glu Pro
         195                 200                 205            
 Val Gly Ser Gln Asp Ser Leu Leu Glu Ile Thr Phe Arg Ser Gly Ala
     210                 215                 220                
 Leu Pro Val Leu Cys Asp Pro Thr Thr Pro Lys Pro Glu Asp Leu His
 225                 230                 235                 240
 Ser Pro Pro Leu Gly Ala Gly Leu Ala Asp Phe Ala His Pro Ala Gly
                 245                 250                 255    
 Ser Pro Leu Gly Arg Arg Asp Cys Leu Val Lys Leu Glu Cys Phe Arg
             260                 265                 270        
 Phe Leu Pro Pro Glu Asp Thr Pro Pro Pro Ala Gln Gly Glu Ala Leu
         275                 280                 285            
 Leu Gly Gly Leu Glu Leu Ile Lys Phe Arg Glu Ser Gly Ile Ala Ser
     290                 295                 300                
 Glu Tyr Glu Ser Asn Thr Asp Glu Ser Glu Glu Arg Asp Ser Trp Ser
 305                 310                 315                 320
 Gln Glu Glu Leu Pro Arg Leu Leu Asn Val Leu Gln Arg Gln Glu Leu
                 325                 330                 335    
 Gly Asp Gly Leu Asp Asp Glu Ile Ala Val
             340                 345    



      <210> 1049
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 1049
 Met Leu Tyr Leu Tyr Ile Ile Ile Val Ser Val Leu Gln Val Lys Glu
   1               5                  10                  15    
 Arg Lys Ile Tyr Ala Asn His Asn Val Ser Leu Glu Val Ile Lys Ile
              20                  25                  30        
 Asp Lys Lys Gln Ser Asn Tyr Ala Lys Tyr Gly Tyr Met Asn Gln Asp
          35                  40                  45            
 Asp Leu Gly Leu Leu Leu Ser Gly Lys Asn Gly Ile Val Leu Glu Glu
      50                  55                  60                
 Lys
  65



      <210> 1050
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 1050
 Met Leu Leu Leu Ser Gln Thr Leu Cys Leu Gly Glu Gln Val Leu Leu
   1               5                  10                  15    
 Gly Ala Trp Leu Val Trp Gly Pro Ser Arg Asp Pro Arg Pro Leu Pro
              20                  25                  30        
 Tyr Leu Cys His Asp Glu Pro Tyr Thr Phe Asp Ile Asn Leu Ser Val
          35                  40                  45            
 Asn Leu Lys Gly Pro Gly Asn Arg Leu Gly Glu Pro Ile Pro Ile Ser
      50                  55                  60                
 Lys Ala His Glu His Ile Phe Gly Met Val Leu Met Asn Asp Trp Ser
  65                  70                  75                  80
 Gly Asn Tyr Trp Ser Ser Val Pro Val Lys Met Thr Gly Lys Glu Leu
                  85                  90                  95    
 Gly Thr Trp Gly Asn Phe Ile Lys Ala Glu Asp Trp Cys Arg Ser Lys
             100                 105                 110        
 Gly Ala Val Met Ala Leu Pro Arg Ala Val Thr Pro Thr Arg Ala Ile
         115                 120                 125            
 Asn Glu Ser Thr Ile Gly Ala Ala Gly Val Asp Asn Glu Val Ser Ser
     130                 135                 140                
 Thr Gly
 145    



      <210> 1051
      <211> 51
      <212> PRT
      <213> Homo sapiens


      <400> 1051
 Met Arg Leu Gly Lys Gly Asn Arg Ser Thr Ala Trp Ala Ser Ser Phe
   1               5                  10                  15    
 Arg Thr Gln Leu Pro Val Leu Leu Leu Ser Phe Leu Arg Phe Thr Leu
              20                  25                  30        
 Trp Val Gly Thr Ala Leu Ser Lys Ala Lys Asn Gln Asn Gly Tyr Lys
          35                  40                  45            
 Ser Arg Glu
      50    



      <210> 1052
      <211> 312
      <212> PRT
      <213> Homo sapiens


      <400> 1052
 Met Leu Leu Ala Gln Ile Arg Thr Val Met Trp Val Cys Trp Ile Phe
   1               5                  10                  15    
 Ile Pro Thr Leu Pro Gly Lys Leu Thr Ser Val Gly Thr Leu Val Ala
              20                  25                  30        
 Arg Leu Ser Ser Gly Phe Trp Gln Asn Leu Ala Asn Gly Met Pro Met
          35                  40                  45            
 Glu Lys Ser Ser Ile Tyr Glu Met Phe Gly Asn Glu Cys Cys Phe Ser
      50                  55                  60                
 Thr Gly Glu Val Ile Lys Ile Thr Gly Leu Lys Val Lys Lys Ile Ile
  65                  70                  75                  80
 Ala Glu Ile Cys Glu Gln Ile Glu Gly Cys Glu Ser Leu Gln Pro Phe
                  85                  90                  95    
 Glu Leu Pro Met Asn Phe Pro Gly Thr Phe Val Lys Arg Ser Lys Glu
             100                 105                 110        
 Cys Leu Phe Lys Ile Val Ala Asp Lys Thr Pro Tyr Leu Thr Met Glu
         115                 120                 125            
 Glu Ile Thr Arg Thr Ile His Ile Gly Pro Ser Arg Leu Gly His Pro
     130                 135                 140                
 Cys Phe Tyr His Gln Lys Asp Ile Lys Leu Glu Asn Leu Ile Ile Lys
 145                 150                 155                 160
 Gln Gly Glu Gln Ile Met Leu Asn Ser Val Glu Glu Ile Asp Gly Glu
                 165                 170                 175    
 Ile Met Val Ser Cys Ala Val Ala Arg Asn His Gln Thr His Ser Phe
             180                 185                 190        
 Asn Leu Pro Leu Ser Gln Glu Gly Glu Phe Tyr Glu Cys Glu Asp Glu
         195                 200                 205            
 Arg Ile Tyr Thr Leu Lys Glu Ile Val Glu Trp Lys Ile Pro Lys Asn
     210                 215                 220                
 Arg Thr Arg Thr Val Asn Leu Thr Asp Phe Ser Asn Lys Trp Asp Ser
 225                 230                 235                 240
 Thr Asn Pro Phe Pro Lys Asp Phe Tyr Gly Thr Leu Ile Leu Lys Pro
                 245                 250                 255    
 Val Tyr Glu Ile Gln Gly Val Met Lys Cys Glu Tyr Pro Leu Arg Met
             260                 265                 270        
 Met Phe Tyr Glu His Glu His Tyr Gly Val Trp Glu Arg Lys Ile Leu
         275                 280                 285            
 Glu Pro Glu Glu Trp Glu Ser Val Phe Ile Ser Thr Ile Glu Pro Val
     290                 295                 300                
 Arg Val Arg Phe Leu Ile Asn Gln
 305                 310        



      <210> 1053
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1053
 Met Met Leu Gly Leu Ala Phe Leu Ala Trp Leu Thr Ala Lys Ala Ser
   1               5                  10                  15    
 His Leu Thr Ser Lys Val Ala Leu Leu Glu Pro Ile Leu His Ser Thr
              20                  25                  30        
 Ala Arg Lys Ile Phe Leu Lys Cys Lys Ser Asp Cys Val Pro Pro Leu
          35                  40                  45            
 Leu Glu Pro Leu Leu Cys Leu Ser Val Ala Leu Met Leu Lys Asp Pro
      50                  55                  60                
 Arg Thr Leu Ser Leu Phe
  65                  70



      <210> 1054
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1054
 Met Leu Lys Met Ser Val Lys Pro Pro Leu Leu Ala Ala Val Ser Leu
   1               5                  10                  15    
 Glu Gln Phe Pro Leu Leu Phe Gly Val Ile Ser Thr Trp Val Arg Lys
              20                  25                  30        
 Leu Ser His Thr Arg Ile Tyr Leu Cys Asn Thr Ile Ser Lys Arg Gln
          35                  40                  45            
 Thr Leu Ala Leu Val Asn Gly Lys Ala Phe Leu Ala Ser His Ile Cys
      50                  55                  60                
 Glu Leu Tyr Arg Tyr Val Ile Ser Phe Asp Leu Ile His Pro Phe Pro
  65                  70                  75                  80
 Phe Ala His Ile Glu Glu Val Lys Gln Met Lys Gly Leu Lys Glu Ala
                  85                  90                  95    
 His Leu Ser Met Lys Val Leu Met Glu Ala Ser Cys Phe Thr Tyr Asp
             100                 105                 110        
 Glu Asn Gly Glu Ser Thr Ser Phe Asp Arg Lys Leu His Phe Phe Gly
         115                 120                 125            
 Thr Glu Asn Arg His Asn Ser His Tyr Val Trp Leu
     130                 135                 140



      <210> 1055
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 1055
 Met Ala His Gly Ala Cys Ala Ala Val Ala Phe Gln Pro Ala Pro Leu
   1               5                  10                  15    
 Ala Leu Arg Ala Ser Thr Leu Ile Trp Ile Lys Ala Ala Ser Ser Ala
              20                  25                  30        
 Thr Ala Lys Val His Val Ile Gly Met Arg Ala Thr Cys Val Ser Glu
          35                  40                  45            
 Ser Val Trp Asp Phe Arg Ala Ala Cys Asn Cys Ser Leu Thr Gln Pro
      50                  55                  60                
 Gln Pro Thr Asp Thr Ser Ser Val Val Lys Thr Glu Gln Arg Asn Ser
  65                  70                  75                  80
 Ala Ser Arg Lys Arg Gln Gly Gln Leu Thr Lys Ser Ser Lys Val Trp
                  85                  90                  95    
 Ser His Gly Arg Cys Asn Leu Tyr Lys Arg Leu Gln Cys Cys Val Arg
             100                 105                 110        
 Ser Asp Ala Phe Ala Glu Trp Ala Trp Arg Ala Gly Arg Lys Glu Ser
         115                 120                 125            
 Glu Ser Ala Met Met Val Leu Leu Leu Lys Thr Ser Asp Thr Gly Thr
     130                 135                 140                
 Leu Thr
 145    



      <210> 1056
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 1056
 Met Met Gly Asn Met Val Arg Pro Val Asn Ser Met Ser Met Asn Leu
   1               5                  10                  15    
 Leu Leu His Phe Phe Ser Cys Lys Val Ser Ala Leu Val Arg Gly Asp
              20                  25                  30        
 Ala Val Trp Asn Thr Met Met Val Asp Lys Ala Phe Arg Lys Ser Thr
          35                  40                  45            
 Asp Gly Ser Leu Gly Arg Ser Ile Ser Tyr Arg Thr Gly Lys Pro Ile
      50                  55                  60                
 Ser Gly Val Val Pro Ala Tyr His Ala Glu Pro Ser Val Asn Gln Ala
  65                  70                  75                  80
 Leu Val Phe Cys Ser Ser Val Asn
                  85            



      <210> 1057
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 1057
 Met Ala Pro Leu Pro Ser Thr Leu Ala Trp Pro Val Gln Ala Phe Phe
   1               5                  10                  15    
 Ala Phe Lys Lys Met Lys Leu Leu Pro Lys Gln Glu Lys Asn Val Arg
              20                  25                  30        
 His Ser Ala Cys Leu Pro Glu Ser Ser Leu Glu Asp Val Gln Lys Val
          35                  40                  45            
 Lys Val Leu His His Gln Ser Lys Phe Ser His Gln Ala Pro
      50                  55                  60        



      <210> 1058
      <211> 206
      <212> PRT
      <213> Homo sapiens


      <400> 1058
 Met Cys Glu Cys Ile Ile Arg Arg Ile Trp Leu Gln Phe Leu Leu Leu
   1               5                  10                  15    
 Ser Ala Ser Glu Lys Ala Gln Lys Gly Val Arg Asp Pro Leu Asn Gly
              20                  25                  30        
 His Ile Gln Gln Ile Leu Leu Val Lys Asn Asn Phe Gly Ser Gly Lys
          35                  40                  45            
 Gln Thr Leu Glu Ala Leu Glu Thr Gly Lys Ala Gly Gln Ile Glu Cys
      50                  55                  60                
 Leu Ile Gly Leu Ala Ser Ser Val Val Tyr Glu Asp Thr Leu Lys Lys
  65                  70                  75                  80
 Ile Val Gln Val Glu Ile Ser Arg Pro Leu Val His Ala Pro Tyr Val
                  85                  90                  95    
 Lys Gly Ile Thr Gly Arg Pro Thr Ala Pro Gly Asp Glu Ala Ile Trp
             100                 105                 110        
 Thr Glu Lys Glu Phe Leu Thr Ser Glu Gly Ala Pro Ile Lys Tyr Pro
         115                 120                 125            
 Glu Ala Ile Arg Arg Leu Leu Leu Ala Val Gln Lys Pro Lys Glu Asn
     130                 135                 140                
 Arg Ser Cys Lys Leu Gln Met Val Leu Gln Met Glu Pro Gln Met Gln
 145                 150                 155                 160
 Pro Met Thr Lys Ile Tyr Trp Gly Pro Leu Asp Trp Pro Ala Ser Pro
                 165                 170                 175    
 Cys Ser Asp Val Asp Asp Ile Glu Gly Asn Pro Pro Glu Glu Ile Ser
             180                 185                 190        
 Thr Ala Gln Pro Leu Leu His Pro Asn Ser Ala Val Ser Ser
         195                 200                 205    



      <210> 1059
      <211> 96
      <212> PRT
      <213> Homo sapiens


      <400> 1059
 Met Thr Asn Ile Pro Thr Pro Leu His Leu Cys Pro Leu Tyr Leu Phe
   1               5                  10                  15    
 Leu Ser Thr Thr Lys Val Phe Pro Ala Thr Ile Leu Ala Cys Pro His
              20                  25                  30        
 Gly Ala Leu His Leu Pro Pro His His Gly Pro Gln Asp Ser Ser Phe
          35                  40                  45            
 Glu Asn Asp Asn Tyr Ser Val Ile Lys Lys Val Lys Phe Thr His Ile
      50                  55                  60                
 His Trp Met Ser Thr Thr Gly Val Gly Phe Gln Arg Ala Ser Asp Thr
  65                  70                  75                  80
 Arg Arg Gln Lys His Gln Glu Ala Pro Ser Ser Ser Leu Val Gln Gln
                  85                  90                  95    





      <210> 1060
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1060
 Met Ala Phe Leu Leu Trp Thr Ser Leu Cys Asp Asp Val Leu Leu Leu
   1               5                  10                  15    
 Gln Leu Ser Cys Asn His Lys Glu Met Ala Ala Asn Asn Gln Gly Trp
              20                  25                  30        
 Gln Ser Glu Lys Met Val Arg Ala Trp Thr Tyr Asp Asp Ile Thr Lys
          35                  40                  45            
 Pro Leu Asn Tyr Leu Val Thr Asp Leu Leu Ser Leu Gly Pro Pro Thr
      50                  55                  60                
 Ser Arg Asp Phe Val Lys Arg Asp Lys Ser Asn Val Gln Ile Ala
  65                  70                  75                



      <210> 1061
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 1061
 Met Leu Gly Pro Leu Ala Ser Leu Ser His Leu Pro Gly Val Pro Ala
   1               5                  10                  15    
 Leu Ser Leu Cys Cys Ser Val Ala Gly Tyr Phe Ala Ser Cys Tyr His
              20                  25                  30        
 Leu Pro Glu Ser Tyr Ala Ala Pro Pro Glu Val Lys Pro Arg Pro Leu
          35                  40                  45            
 Pro Pro Pro Pro Ser Val Pro Thr Pro Pro Pro Glu Pro Pro Thr Ser
      50                  55                  60                
 Leu Asn Ala Pro Ile Gly Thr Pro Thr Phe Asn Ala Ala Thr Gly Ala
  65                  70                  75                  80
 Ser Thr Ser Pro His Thr Ala Ser Ala Thr Met Cys Ser Tyr Ala Thr
                  85                  90                  95    
 Asn Ala Thr Asn Ala Ala Thr Ser Ala Leu Thr Ser Pro Arg Ala Ala
             100                 105                 110        
 Thr Gly Ala Thr Tyr Ser Tyr Ile Ala Thr Gly Ala Thr Thr Arg Ser
         115                 120                 125            
 Tyr Ala Thr Thr Ser Ala Pro Thr Ser Pro Lys Ala Ala Asn Gly Ala
     130                 135                 140                
 Pro Thr Ser Pro His Thr Val Thr Gly Ala Thr Thr Cys Ser Tyr Thr
 145                 150                 155                 160
 Thr Thr Ser Thr Pro Thr Ser Pro Thr Leu Pro Gln Ala Pro Pro Leu
                 165                 170                 175    
 Pro Pro Thr Pro Pro Leu Ala Tyr Thr Gly Asn Gln Ser Pro Arg Ile
             180                 185                 190        
 Asn Leu Trp Thr Thr Ser Ala Pro Ile Ser Val Arg Pro Ala Gly His
         195                 200                 205            
 Leu Pro Gly Val Ala Ala Ser Gly Val Ala Gly Ser Ser Ser Pro Pro
     210                 215                 220                
 Thr Ala Arg Gly Val Cys Ala Lys Ile Arg Ser Asn Cys Asp Glu Gln
 225                 230                 235                 240
 Arg Gln Ala Gln Ala Pro Leu
                 245        



      <210> 1062
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1062
 Met Pro Thr Leu Thr Leu Leu Phe Asn Thr Val Leu Glu Val Leu Ala
   1               5                  10                  15    
 Arg Thr Ile Arg Gln Glu Lys Lys Ile Lys Asp Leu Lys Ile Ser Lys
              20                  25                  30        
 Glu Glu Val Lys Leu Ser Leu Phe Asp Asp Asp Met Ile Leu Tyr Leu
          35                  40                  45            
 Glu Asn Pro Lys Asp Ser Ser Arg Lys Leu Leu Lys Leu Val Asn Glu
      50                  55                  60                
 Phe Ser Lys Val Ser Gly Tyr Lys Ile Asn Val His Lys Ser Val Ala
  65                  70                  75                  80
 Leu Leu Tyr Thr Asn Ser Asp Gln Ala Glu Asn Gln Ile Lys Asn Ser
                  85                  90                  95    
 Thr Thr Phe Thr Ile Ala Ala Lys Lys
             100                 105



      <210> 1063
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1063
 Met Leu Leu Cys Ile Asp Val Leu Leu Leu Pro Val Val Ala Ala Gly
   1               5                  10                  15    
 Ser Asn Asn Gly Gly Gly Gly Thr Glu Thr Cys Glu Gly Ser Asp Gly
              20                  25                  30        
 Asp Leu Ile Thr Glu Ala Leu Thr Asp Ala Thr Ala Glu Ile Tyr Asn
          35                  40                  45            
 Ser Ser Glu Gly Ile Glu Ala Arg Glu Lys Arg Arg Glu Gly Asp Met
      50                  55                  60                
 Ala Arg
  65    



      <210> 1064
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 1064
 Met Asp Pro Arg Leu Leu Leu Ser Leu Ala Ala Tyr Leu Phe Asn Leu
   1               5                  10                  15    
 Ala Tyr Gln Ser Lys Glu Val Glu Thr Glu Ile Ser Leu Phe Pro Gly
              20                  25                  30        
 Ala Asp Arg Thr Glu His Lys Ile Trp Glu Ile Leu Lys Ala Lys Leu
          35                  40                  45            
 Ile Ala Met Ser Phe Glu Glu Ser Gln Ser Glu Ala Thr Ser Phe Thr
      50                  55                  60                
 Thr Ser Val Cys Pro Thr Ile Val Ile Ile Asp Phe Pro Ser Lys Asp
  65                  70                  75                  80
 Gln Ile Arg Glu Val Leu Ser
                  85        



      <210> 1065
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1065
 Met Arg Ser Val Ser Gln His Ala Pro Val Gly Arg Met Arg Ala Phe
   1               5                  10                  15    
 Phe Ala Pro Gln Val Gln Val Ala Leu Cys Leu Arg Pro Pro Ser Leu
              20                  25                  30        
 Glu Leu Ser Thr His Asn Ser Pro Gly Ser His Ala Val Asn Val Phe
          35                  40                  45            
 Leu Met Thr Val Cys Leu Tyr Leu Thr Val Leu Leu Thr Asn Asn Leu
      50                  55                  60                
 Leu Gly Ser Lys Gly Gln His Leu Leu Ser Lys Ala Gln Glu Glu Phe
  65                  70                  75                  80
 Glu Val Asn Gly Phe Ala Ile Val Thr Ile Asn Gly Cys Tyr Ile Lys
                  85                  90                  95    
 Phe Ser Val Ile Phe Val Cys Asp Ser Thr Val Val Trp Val Asn Val
             100                 105                 110        
 His Arg His Asn Trp Leu Asn Pro Lys Ser Leu Ile Ser
         115                 120                 125



      <210> 1066
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1066
 Met Leu Ala Leu Tyr Phe Leu Ile Cys Ile Gln Cys Asn Tyr Thr Phe
   1               5                  10                  15    
 Ser Glu Asp Ser Pro Ala Tyr Leu Pro Arg Ile Pro Pro Gly Lys Val
              20                  25                  30        
 Arg Arg Phe Ala Phe Cys Ile Lys Lys Leu Glu Asn Phe Pro Val Gly
          35                  40                  45            
 Pro Gly Val Ala Pro Pro Val Ser Gly Val Asp Leu Val Pro Ala Glu
      50                  55                  60                
 Thr Ala
  65    



      <210> 1067
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 1067
 Met Asn Thr Trp Ile Phe Cys Leu Ser Phe Met Ala Asn Ser Ser Thr
   1               5                  10                  15    
 Phe Leu Lys Ala Leu Glu Cys Ser Leu Asp Phe His Gly Asn Glu Ala
              20                  25                  30        
 Phe His Ser Ser Tyr Asp Glu Ala Gly Asn Ala Ile Leu Gly Lys Arg
          35                  40                  45            
 Ser Ser Lys Gly Asn Ile Cys Arg Thr Ser Ala Ser Lys Val Arg Gly
      50                  55                  60                
 Lys Leu Arg Gln Leu Lys Thr Phe Gln Ser
  65                  70                



      <210> 1068
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 1068
 Met Val Ser Arg Ala Phe Leu Gly Trp Val Phe Ala Leu Glu Ile Val
   1               5                  10                  15    
 Tyr Ala Phe Val Ile Val Gln Met Val Glu Leu Leu Asp Thr Ala Ala
              20                  25                  30        
 Asn Ile Ala Lys Tyr Ser Thr Arg Gly Ala Asn Ala Ser Ile
          35                  40                  45    



      <210> 1069
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1069
 Met Leu Ser Gln Gln Leu Leu Val Gln Leu Trp Ala Ala Val Gln Ala
   1               5                  10                  15    
 Val Tyr Ser Ile Leu Gly Gln Val Leu Ala Asn Ile Trp Met Pro Trp
              20                  25                  30        
 Gly Ile Arg Ala Cys Ser Ala Met Val Ala Phe Val Ala Lys Arg Leu
          35                  40                  45            
 Cys Ala Ile Arg Arg Arg Glu Glu Leu Ala Gln Gln Asn Leu Val Gln
      50                  55                  60                
 Gly Glu Gly His Arg Lys Arg Ala Val Met Gly Pro Gln Gln Glu Cys
  65                  70                  75                  80
 Met Glu Glu Asp Ala Tyr Cys Leu Asp Leu Asp Arg Arg Leu Gly Lys
                  85                  90                  95    
 Met Gln Asp Asn Trp Lys Pro
             100            



      <210> 1070
      <211> 258
      <212> PRT
      <213> Homo sapiens


      <400> 1070
 Met Leu His Leu Cys Met Cys Ala Leu Leu Val Leu Leu Gly Glu Val
   1               5                  10                  15    
 Val Thr Ala Leu Val His Ala Asp Cys His Arg Arg Glu Ala Ala Ala
              20                  25                  30        
 Ile Pro Leu Trp Ile Gly Lys Thr Leu Glu Gly Gln Trp Arg Ala Ser
          35                  40                  45            
 His Ile Arg Glu Leu Asn Cys Gly Ser Leu Val Val Leu Ser Arg Thr
      50                  55                  60                
 Leu Pro Pro Ala Pro Gly Asn Ala Ala Ala Pro Glu Arg Leu Glu Ala
  65                  70                  75                  80
 Leu Lys Tyr Gln Arg Ile Lys Lys Pro Lys Lys Ser Ser Lys Gly Ser
                  85                  90                  95    
 Ser Lys Ser Lys Lys Arg Ser Gly Leu Leu Val Asn Lys Gly Met Thr
             100                 105                 110        
 Gly Pro His Val Asp Leu Arg Trp Ser Cys Tyr Gln Phe Cys Gly Gly
         115                 120                 125            
 Ile Phe Gln Met Ser Val Phe Ser Pro Gly Pro Phe Pro Glu Val Met
     130                 135                 140                
 Ala Asp Ile Ser Ser Cys Gln Leu Asn Val His Leu Gly Val Ser Tyr
 145                 150                 155                 160
 Ala Phe Thr Met Ser Lys Ala Glu Leu Leu Ile Ser Leu Ser Arg Ser
                 165                 170                 175    
 Ala Ser Pro Gln Leu Phe Leu Gly Leu Ile Thr Ser Thr Asp Asp Ser
             180                 185                 190        
 Ala Ser Gln Thr Gln Gln Leu Pro Asn Ser Gln Val Leu Trp Pro Asp
         195                 200                 205            
 Glu Ala Val Cys Leu Arg Lys Lys Lys Arg His Ser Arg Pro Asp Pro
     210                 215                 220                
 Phe Ala Arg Leu Ser Asp Leu Cys His Arg Gln Leu Pro Glu Asp Gln
 225                 230                 235                 240
 Thr Ala Ile Leu Asn Ser Val Asp His Asp Asp Pro Gly His Ala Thr
                 245                 250                 255    
 Leu Leu
        



      <210> 1071
      <211> 155
      <212> PRT
      <213> Homo sapiens


      <400> 1071
 Met His Phe Ser Ile Arg Cys Ala Ser Gln Arg Ile Pro Cys Arg Gly
   1               5                  10                  15    
 Asn Leu Leu Leu Leu Leu Ser Val Leu Trp Trp Leu Ile Ala Ala Ser
              20                  25                  30        
 Arg Phe Lys Lys Ser His Leu Ser Gly Ser Leu Arg Gly Arg Lys Glu
          35                  40                  45            
 Val Arg Ala Lys Ser Ser Asp Trp Leu Pro Arg Phe Gly Asn Leu Lys
      50                  55                  60                
 Arg Ala His Ile Phe Arg Pro Thr Ser Ile Glu Leu Pro Ser Thr Arg
  65                  70                  75                  80
 Lys Gly Pro Lys Trp Arg Ala Lys Val Cys Gly Cys Pro Tyr Arg Gly
                  85                  90                  95    
 Thr Ser Arg Cys Met Cys Val Trp Pro Arg Gln Ser Ser Ala Arg Gly
             100                 105                 110        
 Leu Gln Cys Leu Gly Ser Glu His His Thr Arg Ser Ile Glu Glu Glu
         115                 120                 125            
 Met Leu Cys Pro Leu Gln His Trp Gly Ser Val Ala Gly Arg Arg Leu
     130                 135                 140                
 Leu Phe Asn Ser His Ser Leu Glu Asp Ser Val
 145                 150                 155



      <210> 1072
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1072
 Met Cys Phe Phe Val Ile Val Val Val Thr Pro Ile Thr Asn Val Gly
   1               5                  10                  15    
 His Gln Asp Leu Ala Leu Lys Ser Ser Thr Asn Thr Val Val Asn Thr
              20                  25                  30        
 Thr Gly Phe Leu Leu Asn Phe Asp Ile Ser Val Arg Leu Met Pro Asp
          35                  40                  45            
 Glu Arg Leu Gly Pro Gly Phe Asp Asp His Gly Leu Arg Glu Glu Pro
      50                  55                  60                
 Glu Cys Gly Pro Asp Ala Lys Trp Glu Met Ala Ala Asn Cys Ile Gly
  65                  70                  75                  80
 Ser Ala Lys Glu Glu Ser Ala Asn Pro Arg Cys Ser Lys Ile Asn Cys
                  85                  90                  95    
 Asn His Leu Thr Val Leu Leu
             100            



      <210> 1073
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1073
 Met Gln Cys Phe Ser Phe Ile Lys Thr Met Met Ile Leu Phe Asn Leu
   1               5                  10                  15    
 Leu Ile Phe Val Ser Thr Asp Ile Val Asp Ser Leu Gly Leu Pro Ile
              20                  25                  30        
 Gly Ala Gly Thr Gly Gly Pro Glu Asn Arg Arg Ala Pro Pro Lys Phe
          35                  40                  45            
 Thr Tyr His Arg Arg Lys Phe Ser Thr Glu Glu Ile Leu Leu Tyr Asp
      50                  55                  60                
 Gly Glu Leu Lys Gly Gly Arg Ala Tyr Leu Ser Ser Glu Gln Gln Ser
  65                  70                  75                  80
 Leu Phe Ile Arg Gln Thr Phe Ile Val
                  85                



      <210> 1074
      <211> 273
      <212> PRT
      <213> Homo sapiens


      <400> 1074
 Met Leu Pro Cys Leu Ala Leu Leu Leu Leu Met Glu Leu Ser Val Cys
   1               5                  10                  15    
 Thr Val Ala Gly Asp Gly Gly Glu Glu Gln Thr Leu Ser Thr Glu Ala
              20                  25                  30        
 Glu Thr Trp Val Ile Val Ala Leu Glu Glu Gly Ala Gly Pro Ser Ile
          35                  40                  45            
 Gln Leu Gln Leu Gln Glu Val Lys Thr Gly Lys Ala Ser Gln Phe Phe
      50                  55                  60                
 Gly Leu Met Gly Lys Arg Val Gly Gly Arg Pro Leu Ile Gln Pro Arg
  65                  70                  75                  80
 Arg Lys Lys Ala Glu Gly Arg Asn Gly Leu Gly Ser Val Val Cys Ser
                  85                  90                  95    
 Val Ala Ser Leu Val Cys Gln Gln Ala Lys Ser Pro Phe Ala Glu Ser
             100                 105                 110        
 Gln Arg Asn Thr Glu Gln Pro Trp Ser Tyr Pro Gln Val Gly Lys Gln
         115                 120                 125            
 Ala Trp Asp Thr Asp Pro Ile Gln Ala Thr Ser Leu Arg Pro Lys Gln
     130                 135                 140                
 Gln Phe Leu Arg Thr Ser Val Cys Ser Val His Lys Gly Arg Ser Gln
 145                 150                 155                 160
 Asp Ser Pro Glu Gly Asp Gly Leu Pro Lys Gly Tyr Cys Thr Cys Gln
                 165                 170                 175    
 Ser Gln Glu Gln Gln Arg Asn Asp Arg Gln Ile Pro Arg Leu Trp Pro
             180                 185                 190        
 Val Ile Ser Tyr Ala Phe Ile Pro Leu Leu Arg Thr Thr Glu Lys Val
         195                 200                 205            
 Pro Glu Gln Met Pro Ser Leu Trp Gln Asn Leu Glu Ile Leu Gln Leu
     210                 215                 220                
 Ile Ala Ile Met Val Lys Ala Glu Glu Pro Lys Thr Thr His His Val
 225                 230                 235                 240
 Pro Ala Glu Met Asp Leu Ala Val Phe Glu His Ala Tyr Gly Ile Pro
                 245                 250                 255    
 Glu Gln Ser Gln Glu Gly Gln Gly Tyr Pro Pro Asn Leu Thr Pro Asp
             260                 265                 270        
 Ala
    



      <210> 1075
      <211> 334
      <212> PRT
      <213> Homo sapiens


      <400> 1075
 Met Ala Ala Glu Leu Asn Gly Leu Leu Trp Arg Leu Gly Trp Ala Gly
   1               5                  10                  15    
 Leu Gly Gly Pro Phe Gln Ala Pro Lys Glu Glu Gly Ser Cys Cys Asn
              20                  25                  30        
 Lys Lys Gln Asp Val Gln Gly Ala Gly Ser Ser Tyr Asn Cys Arg Phe
          35                  40                  45            
 Phe Val Leu Pro Cys Cys Phe Phe Asp Phe Ile Gly Arg Tyr Ser Arg
      50                  55                  60                
 Arg Gln Ser Lys Lys Thr Gln Tyr Arg Glu Tyr Leu Asp Phe Ile Lys
  65                  70                  75                  80
 Glu Val Gly Phe Thr Cys Gly Phe His Val Asp Glu Asp Cys Leu Arg
                  85                  90                  95    
 Ile Pro Ser Thr Lys Arg Val Cys Leu Val Gly Lys Ser Arg Thr Tyr
             100                 105                 110        
 Pro Ser Ser Arg Glu Ala Ser Val Asp Glu Lys Arg Thr Gln Tyr Ile
         115                 120                 125            
 Lys Ser Arg Arg Gly Cys Pro Val Ser Pro Pro Gly Trp Glu Leu Ser
     130                 135                 140                
 Pro Ser Pro Arg Trp Val Ala Ala Gly Ser Ala Gly His Cys Asp Gly
 145                 150                 155                 160
 Gln Gln Ala Leu Asp Ala Arg Val Gly Glu Lys Ala Glu Arg Val Arg
                 165                 170                 175    
 Asn Cys Ala Ala Leu Pro Arg Asp Phe Ile Asp Gln Val Val Leu Gln
             180                 185                 190        
 Val Ala Asn Leu Leu Leu Gly Gly Lys Gln Leu Asn Thr Arg Ser Ser
         195                 200                 205            
 Arg Asn Gly Ser Leu Lys Thr Trp Asn Gly Gly Glu Ser Leu Ser Leu
     210                 215                 220                
 Ala Glu Val Ala Asn Glu Leu Asp Thr Glu Thr Leu Arg Arg Leu Lys
 225                 230                 235                 240
 Arg Glu Cys Gly Gly Leu Gln Thr Leu Leu Arg Asn Ser His Gln Val
                 245                 250                 255    
 Phe Gln Val Val Asn Gly Arg Val His Ile Arg Asp Trp Arg Glu Glu
             260                 265                 270        
 Thr Leu Trp Lys Thr Lys Gln Pro Glu Ala Lys Gln Arg Leu Leu Ser
         275                 280                 285            
 Glu Ala Cys Lys Thr Arg Leu Cys Trp Phe Phe Met His His Pro Asp
     290                 295                 300                
 Gly Cys Ala Leu Ser Thr Asp Cys Cys Pro Phe Ala His Gly Pro Ala
 305                 310                 315                 320
 Glu Leu Arg Pro Pro Arg Thr Thr Pro Arg Lys Lys Ile Ser
                 325                 330                



      <210> 1076
      <211> 291
      <212> PRT
      <213> Homo sapiens


      <400> 1076
 Met Ala Pro Val Gln Thr Leu Arg Thr Ser Thr Ala Thr Leu Leu Phe
   1               5                  10                  15    
 Met Met Val Asn Ile Glu Asp Val Tyr Gly Asn Thr Ala Leu His Asp
              20                  25                  30        
 Ala Val Tyr Asp Lys Gly Thr Ser Leu Ala Gly Ser Leu Leu Ser His
          35                  40                  45            
 His Ala Asn Thr Glu Ala Leu Asn Lys Glu Ser Phe Thr Ala Ile Gln
      50                  55                  60                
 Arg Ala Phe Ser Asn Leu Leu Val Gly Asn Leu Ser Ile Glu His Asp
  65                  70                  75                  80
 Leu Lys Val Ala Ser Glu Glu Lys Gln Glu Thr Leu Glu Arg Ser Glu
                  85                  90                  95    
 Asn Lys Gln Pro Glu Glu Lys Glu Tyr Ile Gln Glu Ile Lys Ser Ile
             100                 105                 110        
 Arg Glu Ile Asn Ala Asn Phe Glu Lys Ser Ala Arg Leu Asn Glu Glu
         115                 120                 125            
 Met Thr Thr Lys Thr Met Ser Gln Tyr Cys Gln Gln Leu Asn Gly Leu
     130                 135                 140                
 Lys Ala Glu Asn Thr Arg Leu Asn Ser Lys Leu Glu Lys Glu Glu His
 145                 150                 155                 160
 His Thr Asp Gly Leu Glu Ala Glu Val Glu Phe Phe His Ser Arg Leu
                 165                 170                 175    
 Ala Ala Ala Ile Asn Glu His Asn Glu Ser Leu Glu Thr Lys Asp Leu
             180                 185                 190        
 Glu Leu Val Leu Gln Arg Ala His Asn Phe Ser Val His Lys Lys Ile
         195                 200                 205            
 Ser Ser Thr Val Ser Gln Leu Lys Asp Lys Asn Glu Leu Leu Thr Glu
     210                 215                 220                
 Gln Phe Ser Lys Ala Gln Met Lys Phe Asn Thr Leu Lys Gly Lys Leu
 225                 230                 235                 240
 His Glu Ile Arg Asp Ala Leu Arg Glu Lys Thr Leu Ala Leu Glu Ser
                 245                 250                 255    
 Val Gln Met Asp Gln Arg Gln Ala Gln His Arg Ile Lys Glu Met Glu
             260                 265                 270        
 Gln Ile His Pro Asn Glu Glu Thr Lys Gly Val Asp Pro Pro Glu Ser
         275                 280                 285            
 Thr Thr Val
     290    



      <210> 1077
      <211> 143
      <212> PRT
      <213> Homo sapiens


      <400> 1077
 Met Thr Leu Lys Gly Gly Glu Leu Pro Ile Pro Arg Gly Ala Phe Leu
   1               5                  10                  15    
 Ile Leu Leu Leu Ser Pro Val Ser Thr Asp Gln Ala Asn Thr Thr Thr
              20                  25                  30        
 Ala Glu Ile His Ser Gln Leu Thr Pro Arg Leu Asn Leu Thr Ile Leu
          35                  40                  45            
 Ser Ser Gln Lys Asn Ala Glu Thr Asn Ala Ile His His Ile Gln Tyr
      50                  55                  60                
 Asn Val Asp Gly Lys Cys Trp Ala Arg Pro Gln Lys Gln Cys Thr Met
  65                  70                  75                  80
 Tyr Thr Gly Arg Gly Gln Val Phe Ser Arg Gly Ser Arg Thr Ile Glu
                  85                  90                  95    
 Ile Thr Asn Gln Thr Ile Ser Lys Gln Thr Ser Tyr Ser Lys Glu Ile
             100                 105                 110        
 Pro Leu Ser Ile Gln Glu Asn Ala Gln Met Gly Leu Arg Ile Tyr Ser
         115                 120                 125            
 Ala Pro Ala Tyr Ala His Gln His Thr Gly Ile His Ser Pro Ala
     130                 135                 140            



      <210> 1078
      <211> 129
      <212> PRT
      <213> Homo sapiens


      <400> 1078
 Met Gly Pro Tyr Trp Val Trp Leu Cys Leu Ala Ala Gly Ser Pro Asn
   1               5                  10                  15    
 Thr Glu Asp Met His Ile Ser Ala Gly Leu Thr Met Val Ile Cys Pro
              20                  25                  30        
 Asn Pro Arg Ile Gln Arg Leu Lys Thr Lys Tyr Ser His Thr Lys Ala
          35                  40                  45            
 Thr Gln Leu Thr Ala Tyr Cys Gln Leu Lys Gln Lys His Arg Tyr Ser
      50                  55                  60                
 Ser Glu Glu Tyr Tyr Arg Thr Gln Ser Leu His Asn Val Thr Phe Ile
  65                  70                  75                  80
 Asn Met Gln Asp Thr Ile Gln Asn Asp Ser Ile Tyr Lys Glu Pro Glu
                  85                  90                  95    
 Glu Tyr Asp Pro Phe Ser Arg Glu Lys Thr Phe Asn Arg Asn Gln Ser
             100                 105                 110        
 Gln Asn Asp Thr Asn Val Gln Thr His Lys Glu Gln Thr Asn Glu Thr
         115                 120                 125            
 Glu
    



      <210> 1079
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1079
 Met Ala Ala Leu Leu Leu Arg His Val Gly Val Val Ile Ala Ser Glu
   1               5                  10                  15    
 Arg Thr Leu Ala Leu Ser Phe Val Ser Glu Met Leu Phe Leu Trp Glu
              20                  25                  30        
 Ser Trp Pro Lys Lys Arg Trp Asn Gly Ser Gly Ile Arg Thr Gln Val
          35                  40                  45            
 Gln Thr Val Pro Tyr Leu Pro Thr Ser Leu Ser Arg Val Gly Val Phe
      50                  55                  60                
 Leu Cys Arg Cys Pro Ser Ala Thr Met Ala Leu Gly Trp Gln Leu Cys
  65                  70                  75                  80
 Glu Glu Leu Ser Leu Pro Asn Leu Gly Leu Glu Ala Val Ile Leu Ser
                  85                  90                  95    
 Pro Tyr Trp Ala Leu Ile Cys Ala Glu Gly Gln Leu Leu Ala Pro Pro
             100                 105                 110        
 Ser Trp Asp Ile Gly Asn Asn Ala Ser Ser Val Ala Ser Ala Leu Gly
         115                 120                 125            
 Thr Gly Gly Glu Ala Leu Gly Thr Thr Ala Trp Leu Ser Asp Asp Leu
     130                 135                 140                
 His Trp Leu Val Phe Ser Ala Phe Thr
 145                 150            



      <210> 1080
      <211> 234
      <212> PRT
      <213> Homo sapiens


      <400> 1080
 Met Tyr Leu Phe Leu Cys Pro Pro Leu Ala Leu Val Gln Cys Ala Leu
   1               5                  10                  15    
 Lys Asp Pro Arg Ser Lys Tyr Ser Leu Gly Gly Arg Thr Thr Leu Ile
              20                  25                  30        
 Ile Thr Leu Gln Gly Ser Gly Lys Lys Asn Asn Ile Pro His Pro Ser
          35                  40                  45            
 Ser Leu Ser Glu Arg Val Met Thr Ala Lys Asp Gly Phe Val Ser Arg
      50                  55                  60                
 Cys His Leu Leu Met Gln Pro Lys Gln Gln Glu Asn Gly Cys Trp Pro
  65                  70                  75                  80
 Thr Leu Gln Asp Ser Leu Leu Cys Thr Ala Leu Val Asp Lys Leu Leu
                  85                  90                  95    
 Val Phe Leu Gly Arg Cys Phe Cys Thr Ala Val Glu Val Val Met Leu
             100                 105                 110        
 Val Thr Cys Arg Thr Ala Ala Ala Val Ser Ala Phe Leu Ile Val Gly
         115                 120                 125            
 Arg Val Ser Ser Pro Val Cys Arg Ala Val Ser Val Gln Pro Trp Thr
     130                 135                 140                
 Leu Thr Ala Asp His Thr Pro Gly Arg Tyr Cys Leu Lys Leu Val Cys
 145                 150                 155                 160
 Arg Gln Leu Cys Leu Cys Leu Leu Ala Glu Phe Ser Glu Lys Gly Thr
                 165                 170                 175    
 Ile Cys Leu His Gln Asn Phe Met Cys Thr Phe Ala Ala Ile Ser Ile
             180                 185                 190        
 Glu Ser Glu Asp Thr Thr Glu Gln Leu Ala Gly Ser Phe Leu Ile Ile
         195                 200                 205            
 Phe Trp Lys Val Asp Pro Glu Leu Leu Cys His Arg Ser Gln Thr Ala
     210                 215                 220                
 Lys Glu Asn Val Asp Ile Trp Gly Ser Leu
 225                 230                



      <210> 1081
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 1081
 Met Ala Leu Ile Thr Trp Leu Pro Arg Pro Thr Trp Pro Leu Asp Phe
   1               5                  10                  15    
 Gln Leu Tyr Glu Thr Met Trp Val Lys Gln Ala Tyr Tyr Leu Pro Phe
              20                  25                  30        
 Thr Thr Gly Glu Thr Gly Trp Arg Ala Tyr Val Asn His Pro Arg Phe
          35                  40                  45            
 Pro Ser Cys Gln Val Val Val Pro Glu Pro Glu Pro Val Ser Ala Ala
      50                  55                  60                
 Ser Lys Ala His Ala Leu Pro Pro Pro Gln Ala Ser Glu Gly Arg Ala
  65                  70                  75                  80
 Val Asp Gly Thr Ser Arg Gln Glu Thr Met Lys Leu Ser Ser Thr Val
                  85                  90                  95    
 His Gly Ser His Gly Leu Pro Gly Cys Gln Ala Ala Ser Arg Ile Pro
             100                 105                 110        
 Asp Glu
        



      <210> 1082
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 1082
 Met Arg Lys Ile Val Val Gly Leu Thr Phe Leu Ile Thr Arg Thr Cys
   1               5                  10                  15    
 Val Val Lys Ala Ser Thr Ala Ser Ser His Thr Glu Asp Cys Phe Gln
              20                  25                  30        
 Cys Ile Pro Gln Val Thr Glu Leu Gln Ala Val Leu Glu Ile Ile Thr
          35                  40                  45            
 Asn Lys Thr Gly Gln Ala Leu Thr Val Leu Ala Arg Gln Glu Thr Gln
      50                  55                  60                
 Met Arg Asn Ala Ile Tyr Gln Asn Arg Leu Ala Leu Asp Tyr Leu Leu
  65                  70                  75                  80
 Ala Ala Lys Gly Gly Val Cys Gly Lys Phe Asn Leu Thr Asn Cys Cys
                  85                  90                  95    
 Leu His Ile Asp Asp Gln Gly Gln Val Val Glu Asp Ile Val Lys Asp
             100                 105                 110        
 Ile Thr Lys Leu Ala His Val Gln Cys Glu Pro Phe Thr Asp Thr Cys
         115                 120                 125            
 Trp Ser Leu Pro Leu Gly Gln Gly Asn Thr Val Val Asn Glu Ser Gln
     130                 135                 140                
 Lys Ser Asp Val Lys Val Arg Ser Lys Ser Asp Arg Gly
 145                 150                 155        



      <210> 1083
      <211> 155
      <212> PRT
      <213> Homo sapiens


      <400> 1083
 Met Trp Ala Lys Val Leu His Leu Met Leu Gly Trp Lys Asn Leu Lys
   1               5                  10                  15    
 Ala Ala Leu His Leu Pro Ser Cys Cys Gly Leu Ser Gln Arg Leu Arg
              20                  25                  30        
 Lys Pro Gly Asp Arg Lys Gln Asn Ala Asn Pro Lys Ser His Leu Ala
          35                  40                  45            
 Lys Leu Ser Phe Ile Val Asn Ile Phe Thr Ile Trp Gly Lys Leu Lys
      50                  55                  60                
 Ser Cys Phe Pro Leu Gly Thr Ala Lys Thr Ile Ile Ser Met Tyr Leu
  65                  70                  75                  80
 His Pro Ser Ser Arg Ser Pro Tyr Pro Leu Pro Tyr Phe Tyr Arg Gly
                  85                  90                  95    
 Leu Leu Tyr Gly Asp Cys Arg Lys Pro Ala Ser Val Ala Asn Thr Trp
             100                 105                 110        
 Arg Arg Ala Arg Ser Leu Ala Gln Arg Phe His Gly Ala Gln Val Arg
         115                 120                 125            
 Ser Ser Lys Lys Ser Leu Gln Thr Ser Ala Pro Gly Ser Arg Phe Pro
     130                 135                 140                
 Leu Gln Tyr Gly Ser Arg Leu Lys Gln Pro Glu
 145                 150                 155



      <210> 1084
      <211> 261
      <212> PRT
      <213> Homo sapiens


      <400> 1084
 Met His Val Gln Gly Lys Ala Ala Ile Leu Gly Arg His Phe Ser Ile
   1               5                  10                  15    
 Ser Ser Leu Leu Pro Gly Ala Leu Leu Leu Leu Thr Val Ile Lys Gly
              20                  25                  30        
 His Thr His Pro Glu Glu Lys Ser Pro Gly Ala His Glu Lys Ala Val
          35                  40                  45            
 Thr Gly Glu Pro Lys Cys Leu Gly Ala Leu Pro Tyr Cys Asp Ser Gly
      50                  55                  60                
 Gly Lys Lys Ala Thr Lys Lys Lys Asp Ala Gly Glu Met Arg Ser Arg
  65                  70                  75                  80
 Ile Lys Asp Gly Val Leu Val Leu Lys Cys Ile Ser Leu Gln Val Gly
                  85                  90                  95    
 Leu Ala Ser Trp Ile Val Ser Trp Leu Arg Thr Glu Ala Thr Gly Tyr
             100                 105                 110        
 Thr Phe Ala Leu Leu Pro Pro Gly Thr His His Thr Glu Gln Thr Pro
         115                 120                 125            
 Ser Lys His Glu Gln Asn Gly Ala Glu Leu Phe Cys Asn Cys Val Ser
     130                 135                 140                
 Cys Phe Glu Asp Pro Cys Pro Cys Gln Val Pro Gly Thr Gln Pro Gly
 145                 150                 155                 160
 Asn Arg Leu Ser Glu Glu His Gln Ala Ser Ser Gln Ala Asp Val Thr
                 165                 170                 175    
 Asn Ser Ser Ala Pro Lys Gln Pro His Pro Pro Pro Ala Pro Cys Lys
             180                 185                 190        
 Val Ser Val His Ile Ala Glu Leu Gly Glu Ile Val Cys Gln Ser Leu
         195                 200                 205            
 His Lys Thr Gly Ala Ser Asp Leu Cys Glu Val His Lys Val Glu Val
     210                 215                 220                
 Met Ser Glu Arg Asp His Glu Arg Phe Lys Tyr Gly Tyr Gly Val Ile
 225                 230                 235                 240
 Ser Val Ile Thr Asn Ser Leu Lys Ile Lys Glu Ser Gly Asn Lys Leu
                 245                 250                 255    
 Ala Cys Cys Arg Gln
             260    



      <210> 1085
      <211> 194
      <212> PRT
      <213> Homo sapiens


      <400> 1085
 Met Ser Leu Leu Gln Val Lys Ser Pro Thr Trp Phe Arg Lys Ala Ile
   1               5                  10                  15    
 Cys Leu Leu Leu Arg Ser Ala Ala His Gly Leu Ser Ala Pro Asp Arg
              20                  25                  30        
 Tyr Thr Ser Leu Pro Leu Gln Ser Pro Asp Gln Glu Arg Gly Gly Phe
          35                  40                  45            
 Thr Ser Gly Gly His Gln Gly Ser Val Met Ser Arg Glu Leu Glu Cys
      50                  55                  60                
 Gly His Leu Gly Arg Ser Gly Gly Asp Gly Asp Thr Glu Trp Gln Gly
  65                  70                  75                  80
 Glu Ile Ser His Pro Asn Ser Ile Thr Leu Pro Ala Gln Ser Pro Leu
                  85                  90                  95    
 Lys Pro Phe Ser Ser Leu Phe Thr Gly Ile Met Ile His Ser Asn Ile
             100                 105                 110        
 Gln Leu Thr Gln Pro Phe Lys Asn Val Lys Ile Ile Leu Gly Ser Glu
         115                 120                 125            
 Ala Val Gln Lys Gln Gly Val Gly Cys Phe Ser Cys Gly Leu Ser Cys
     130                 135                 140                
 Gly Asp Leu Tyr Ala Lys His Arg Leu Ser Leu Ser Ser Ala Ala Arg
 145                 150                 155                 160
 Ser Pro Asp Pro Gln Gln Thr Ser Phe Pro Val Pro Val Thr Gly Leu
                 165                 170                 175    
 Ser Leu Ser Ser Ala Asn His Gly Val Leu Val Arg Pro Thr Ala Thr
             180                 185                 190        
 Lys Met
        



      <210> 1086
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1086
 Met Ser Arg Lys Val Val Leu Val Thr Ser Thr Leu Leu Leu Ile Ser
   1               5                  10                  15    
 Arg Ser Ser Ser Ala Thr Met Leu Ser Leu Gln Asp Arg Asp Ala His
              20                  25                  30        
 Asp Pro Gln Leu Gly Trp Pro Leu Trp Asp Leu Arg Gly Ser Pro Ser
          35                  40                  45            
 Leu Glu Ala Asp Arg Ser Arg Glu Ala Ser Asp Leu Thr Ala Leu Gly
      50                  55                  60                
 Arg Gln Gln Leu Lys Ala Tyr Glu Leu Leu Gln Pro Gln Gln Leu Gly
  65                  70                  75                  80
 Gly Ala Cys His Leu Val Gly Lys Leu Ala Asn Val Arg Asn Pro Glu
                  85                  90                  95    
 Thr Ser
        



      <210> 1087
      <211> 199
      <212> PRT
      <213> Homo sapiens


      <400> 1087
 Met Ala Lys Gly Trp Pro His Cys Leu Arg Val Val Ala Ala Val Val
   1               5                  10                  15    
 Val Leu Val Ser Glu Ala Val Lys Leu Ile Gln Gly Arg Asp Leu Thr
              20                  25                  30        
 Val Trp Thr Ser His Asp Val Asn Gly Ile Leu Thr Ala Lys Gly Asp
          35                  40                  45            
 Leu Trp Leu Ser Asp Asn His Leu Leu Lys Tyr Gln Ala Leu Leu Leu
      50                  55                  60                
 Glu Gly Pro Val Leu Arg Leu Cys Thr Cys Ala Thr Leu Asn Pro Ala
  65                  70                  75                  80
 Thr Phe Leu Pro Asp Asn Lys Glu Lys Ile Glu His Asn Cys Gln Gln
                  85                  90                  95    
 Val Ile Val Gln Thr Tyr Ala Ala Gln Gly Asp Pro Leu Glu Val Pro
             100                 105                 110        
 Leu Thr Asp Pro Asp Leu Thr Leu Cys Thr Asp Gly Ser Ser Phe Val
         115                 120                 125            
 Glu Lys Gly Leu Arg Lys Val Gly Ile Lys Ala Val Lys Leu Gln Ile
     130                 135                 140                
 Ile Leu Gln Met Glu Pro Gln Met Pro Ser Met Thr Lys Ser Tyr Arg
 145                 150                 155                 160
 Gly Pro Leu Asp Arg Pro Ala Ser Pro Cys Ser Asn Val Asn Asp Ile
                 165                 170                 175    
 Glu Gly Thr Pro Pro Glu Glu Ile Ser Thr Ala Gln Pro Leu Leu Cys
             180                 185                 190        
 Pro Asn Ser Gly Gly Ser Ser
         195                



      <210> 1088
      <211> 45
      <212> PRT
      <213> Homo sapiens


      <400> 1088
 Met Leu Cys Leu Pro Ala Val Leu Pro Gly Ala Leu Leu Pro Leu Val
   1               5                  10                  15    
 Trp Pro Phe Ala Glu Cys Thr Gly Glu Phe Gly Ala Ala Ala Asp Ser
              20                  25                  30        
 Gly Asp Val Ala Arg Ala Ala Gly Tyr Gln Gln Cys Arg
          35                  40                  45



      <210> 1089
      <211> 378
      <212> PRT
      <213> Homo sapiens


      <400> 1089
 Met Arg Ser Leu Pro Ser Leu Gly Gly Leu Ala Leu Leu Cys Cys Ala
   1               5                  10                  15    
 Ala Ala Ala Ala Ala Ala Ala Val Ala Ser Ala Ala Ser Ala Gly Asn
              20                  25                  30        
 Val Thr Gly Gly Gly Gly Ala Ala Gly Gln Gly Asp Gly Ser His Gly
          35                  40                  45            
 Pro Gly Pro Glu Asp Arg Ala Pro Ala Arg His Arg Pro Pro Thr Pro
      50                  55                  60                
 Gly Cys Asp Phe Ser Ser Pro Val Pro Gly Asp His Pro Ser Leu Gly
  65                  70                  75                  80
 Asp Cys Trp Thr Leu Phe His His Leu Ser Gly Ala Ala Arg Pro Leu
                  85                  90                  95    
 Ala Asp His Pro Ser Gly Gly Gly Thr His Phe Asp His Leu Ser Gly
             100                 105                 110        
 Ala Asp Gln Thr Arg Ala Asp His Pro Phe Asp Asp His Trp Pro Gly
         115                 120                 125            
 Ala Asp His Pro Cys Ser Asp His Arg Thr Gly Ala His Asp Ser Pro
     130                 135                 140                
 Asp Pro Asp Pro Arg Ser Pro Gln Gln Gln Gln Gln Gln Arg Pro Pro
 145                 150                 155                 160
 His Pro Thr Cys His Arg Gly Pro Leu Phe Ala Ser Ser Arg Met Ala
                 165                 170                 175    
 Gln Val Lys Leu Glu Leu Ser Cys Val Met Leu Pro Val Thr Ala Val
             180                 185                 190        
 Met Val Leu Leu Arg Thr Gly Leu Asn Arg Arg His Phe Lys Lys Ala
         195                 200                 205            
 Asn Ala Lys Met Glu Ile Pro Lys Thr Ala Ile Val Gln Phe Trp Leu
     210                 215                 220                
 Val Ile Ser Gln Ile Arg Gln Arg Ser Ser Cys Tyr Ser Thr Ile Asp
 225                 230                 235                 240
 Pro Thr Arg Phe Glu Tyr Val Phe Gln Leu Asp Tyr Ile Leu Gln Leu
                 245                 250                 255    
 Lys Ser Lys Tyr Leu Pro Leu Thr Gln Pro Val Met Asn Leu Arg Val
             260                 265                 270        
 Ser Glu Ala Val Lys Thr Gly Arg Lys Ile Val Met Gly Arg Glu Arg
         275                 280                 285            
 Met Lys Ile Val Ile Arg Ser Lys Met Ser Gly Tyr Ser Gln Ile Trp
     290                 295                 300                
 Gln Cys Val Leu Leu Gln Met Ile Glu Leu Glu Glu Thr Thr Phe Leu
 305                 310                 315                 320
 Trp Asn Asp Asp Arg Ile Tyr Gln Lys Leu His Thr Ser Thr Gln Leu
                 325                 330                 335    
 Ser Trp Ile Pro Val His Thr Met Lys Pro Glu Val Val Met Met Ala
             340                 345                 350        
 Phe Met Asn Leu Lys Glu Ala Ala Gly Phe His His Thr Thr Val Ser
         355                 360                 365            
 Pro Lys Lys Ser Asn Pro Cys Lys Lys Gly
     370                 375            



      <210> 1090
      <211> 81
      <212> PRT
      <213> Homo sapiens


      <400> 1090
 Met Val Ser Ala Ala Gln Gly Gln Ala Leu Tyr Leu Leu Leu Cys Ala
   1               5                  10                  15    
 Arg Glu Phe His Thr Ala Thr Val Gln Ser Arg Asn Gln Pro Glu Pro
              20                  25                  30        
 Ala His Gly Val Asn Tyr Ser Val Lys Thr Glu Ala His Ser Thr Gly
          35                  40                  45            
 Thr Thr Ala Glu Pro Leu Ser Ser Gln Asp Arg Ala Val Arg Gly His
      50                  55                  60                
 Asn Thr Asp Ser His Val Gln Thr Pro Asp Leu Gly Glu Asp Thr Ala
  65                  70                  75                  80
 Leu
    



      <210> 1091
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 1091
 Met Leu His Thr Leu Glu Leu Leu Phe Leu Leu Lys Ile Asn Pro Leu
   1               5                  10                  15    
 Leu Ser Phe Phe Phe Leu Gln Leu Val Glu Phe Phe Pro Asp Lys Asp
              20                  25                  30        
 Lys Gly Glu Thr Ser Glu Gly Gly Ala Glu Ser Phe Ser Ser Glu Ser
          35                  40                  45            
 Pro Gly Glu Asn Gln Leu Tyr Ser Glu Met Gln Phe Phe Tyr Leu Cys
      50                  55                  60                
 Glu Gln Arg Ala Val Val Pro Thr Glu Ser Trp Val Gly Leu Ile Asn
  65                  70                  75                  80
 Leu Phe Phe Met Ala Ser Trp Met Lys His Ser Gly Lys Leu Trp Ser
                  85                  90                  95    
 Lys Arg Asn
            



      <210> 1092
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1092
 Met Val Leu Met Cys Gly Val Arg Cys Leu Val Trp Gly Met Phe Met
   1               5                  10                  15    
 Gly Tyr Val Pro Lys Asp Leu Arg Thr Tyr Gln Val Leu Glu Tyr Leu
              20                  25                  30        
 Ser Ser Ser Cys Val Pro Ala Ala Gly Leu Gln Asp Gly Trp Val Leu
          35                  40                  45            
 Gly Asp His Ala Val Ala Glu Glu Ala Gly Tyr Ser Pro Gln Ala Arg
      50                  55                  60                
 Asp Ser Pro Leu Pro Val His Thr Asn Lys Val Leu Leu Glu His Ser
  65                  70                  75                  80
 His Thr Tyr Phe Ser Ala Tyr Cys Leu Trp Leu Leu Ser Cys Tyr Ile
                  85                  90                  95    
 Gly Glu Leu Asn Ser Cys Asp Arg Asp Leu Trp Pro Ala Met Leu Asn
             100                 105                 110        
 Tyr Leu Pro Ser Gly Pro Arg Glu Lys Gln Lys Lys Cys
         115                 120                 125



      <210> 1093
      <211> 43
      <212> PRT
      <213> Homo sapiens


      <400> 1093
 Met Gln Lys Ile Trp Thr Pro Asp Thr Leu Leu Ser Tyr Leu Gln Val
   1               5                  10                  15    
 Leu Leu Cys Ser Val Leu Pro Asn His Phe Leu Lys Asn Ile Tyr Leu
              20                  25                  30        
 Cys Thr Lys His Thr Arg Ser Ala Gln Pro His
          35                  40            



      <210> 1094
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 1094
 Met Ala Leu Ser Leu Phe Ala Val Gln Ser Lys Ser Arg Ile Cys Phe
   1               5                  10                  15    
 Ala Val Cys Val Leu Lys Leu Val Pro Cys Glu Leu Leu Ser Ala Pro
              20                  25                  30        
 Cys Gln Ala Val Ser Gly Gly Val Ser Leu Cys Glu Asp Ala Val Phe
          35                  40                  45            
 Ser Asp Gly Leu Ser Cys Gln Arg Val Ala Ser Val Arg Leu Ser Phe
      50                  55                  60                
 Leu Leu Leu Arg Asn Pro Arg Ala Arg Arg Ala Val Ser Ala Gly Asp
  65                  70                  75                  80
 Trp Cys Ser Glu Ala Ala Gly Ile Lys Leu Ala Trp Ala Ala Ala Val
                  85                  90                  95    
 Gly Ser Glu Cys Ser Ile Pro Arg Gly Ala Ala Pro Ala Ala Asp Asp
             100                 105                 110        
 Met Gly Pro
         115



      <210> 1095
      <211> 300
      <212> PRT
      <213> Homo sapiens


      <400> 1095
 Met Pro Gly Arg Leu Leu Leu Thr Leu Leu Arg Phe Gly Gly His Gly
   1               5                  10                  15    
 Ala Val Gln Leu Glu Arg Leu Cys Pro Lys Ile Cys Val Val Pro Val
              20                  25                  30        
 Ser Leu Pro Phe Gly Gln Asn Ala His Gln Ile Ala Glu Phe Gly Pro
          35                  40                  45            
 Gly Arg Leu Gly Asn Arg Pro Arg Arg Asn Gly Trp Asp Leu Ile Gly
      50                  55                  60                
 Gly Gln Arg Leu Pro Val Arg Pro Leu Leu Glu Leu Pro Ala Leu Met
  65                  70                  75                  80
 Trp Ala Gly Arg Pro Lys Gly Glu Ser Arg Leu Arg Leu Leu Val Lys
                  85                  90                  95    
 Trp Glu Asn Gly Leu Asp Arg Gly Arg Ser Ile Ser Ile His Lys Ala
             100                 105                 110        
 His Gly Gly Asp Gly Cys Phe Pro Glu Lys Ser Leu Leu Lys Arg Arg
         115                 120                 125            
 Ser Pro Arg Pro Phe Gly Ser Pro Ile Gly Val Leu Arg Ala Cys Lys
     130                 135                 140                
 Ser Cys Ser Arg Ser Ser Pro Arg Ser Leu Ser Arg Val Thr Arg Glu
 145                 150                 155                 160
 Gly Pro Arg Gly Ile Leu Leu Arg Lys Thr Phe Gln Cys Leu Lys Asp
                 165                 170                 175    
 Tyr Phe Leu Thr Tyr Tyr Thr Ser Ser Lys Val Val Pro Val Lys Val
             180                 185                 190        
 Pro Cys Arg Gln Val Leu Thr Ile Asp Lys Cys Ser Leu Pro Arg Ser
         195                 200                 205            
 Ser His Arg Asn Ala Arg Thr Val Ser Asn Asp Phe Pro Arg Lys Ser
     210                 215                 220                
 Cys Ser Arg Glu Arg Cys Thr His Cys Met Arg Pro Pro Glu Gly Arg
 225                 230                 235                 240
 Arg Pro Pro Asn Gly Asn Met Asn Ser Trp Lys Trp Pro Ser Gly Asp
                 245                 250                 255    
 Val Val Val Thr Gln Phe Leu Tyr Ser Asp Thr Phe Asn Asn Val Ser
             260                 265                 270        
 Gln Phe Ala Gly Leu Ser Arg Met Leu Pro Gln Glu Ala Asn Ser Gln
         275                 280                 285            
 Arg Pro Asp Ala Arg Leu Pro Ala Asp Glu Gln Lys
     290                 295                 300



      <210> 1096
      <211> 380
      <212> PRT
      <213> Homo sapiens


      <400> 1096
 Met Ala Val Met Ile Ile Thr Ile Ile Ser Val Leu Ser Cys Asp Gly
   1               5                  10                  15    
 Leu Ser Phe Thr Leu Asp Lys Gly Gly Pro Gln Met Glu Lys Gly His
              20                  25                  30        
 Gln Arg His Val Ala Arg Gly Gly Lys Gln Ala Ser Asn Ser Pro Asn
          35                  40                  45            
 His Leu Gly Thr Thr Lys Tyr Thr Pro Ser Thr His Thr Phe Pro Pro
      50                  55                  60                
 Asn Asn Arg Val Phe Ala Ile Ser Ser Val Ala Thr Arg Gln Pro Cys
  65                  70                  75                  80
 Ser Thr Gly Arg Arg Gly Trp Glu Pro Gly Ile Ile Val Phe Lys Ser
                  85                  90                  95    
 Cys Gln Val Ile Pro Ile Ala Ala Lys Val Ala Asn Pro Ala Phe Ser
             100                 105                 110        
 Trp Lys Ser Pro Phe Gly Ser Thr Glu Arg Lys Thr Pro Val Lys Lys
         115                 120                 125            
 Leu Ala Pro Glu Phe Ser Lys Val Lys Thr Lys Thr Pro Lys His Ser
     130                 135                 140                
 Pro Ile Lys Glu Glu Pro Cys Gly Ser Leu Ser Glu Thr Val Cys Lys
 145                 150                 155                 160
 Arg Glu Leu Arg Ser Gln Glu Thr Pro Glu Lys Pro Arg Ser Ser Val
                 165                 170                 175    
 Asp Thr Pro Pro Arg Leu Ser Thr Pro Gln Lys Gly Pro Ser Thr His
             180                 185                 190        
 Pro Lys Glu Lys Ala Phe Ser Ser Glu Ile Glu Asp Leu Pro Tyr Leu
         195                 200                 205            
 Ser Thr Thr Glu Met Tyr Leu Cys Arg Trp His Gln Pro Pro Pro Ser
     210                 215                 220                
 Pro Leu Pro Leu Arg Glu Ser Ser Pro Lys Lys Glu Glu Thr Val Ala
 225                 230                 235                 240
 Ile Pro Ser Trp Arg Asp His Ser Val Glu Pro Leu Arg Asp Pro Asn
                 245                 250                 255    
 Pro Ser Asp Leu Leu Glu Asn Leu Asp Asp Ser Val Phe Ser Lys Arg
             260                 265                 270        
 His Ala Lys Leu Glu Leu Asp Glu Lys Arg Arg Lys Arg Trp Asp Ile
         275                 280                 285            
 Gln Arg Ile Arg Glu Gln Arg Ile Leu Gln Arg Leu Gln Leu Arg Met
     290                 295                 300                
 Tyr Lys Lys Lys Gly Ile Gln Glu Ser Glu Pro Glu Val Thr Ser Phe
 305                 310                 315                 320
 Phe Pro Glu Pro Asp Asp Val Glu Ser Leu Met Ile Thr Pro Phe Leu
                 325                 330                 335    
 Pro Val Val Ala Phe Gly Arg Pro Leu Pro Lys Leu Thr Pro Gln Asn
             340                 345                 350        
 Phe Glu Leu Pro Trp Leu Asp Glu Arg Ser Arg Cys Arg Leu Glu Ile
         355                 360                 365            
 Gln Lys Lys Gln Thr Pro His Arg Thr Cys Arg Lys
     370                 375                 380



      <210> 1097
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 1097
 Met Pro Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu
   1               5                  10                  15    
 Leu Arg Asn Arg Val Glu Asp Pro Phe Ser Ser Leu Gly Thr Phe Ser
              20                  25                  30        
 Ser Ser Lys Met Ala Phe Lys Pro Lys Met Glu Glu Gly Trp Leu Ile
          35                  40                  45            
 Ile Ser Pro Leu Ser Lys Trp Asp Pro Arg Val Val Pro Glu Val Tyr
      50                  55                  60                
 Lys Thr Gly Phe Arg Gly Asp Lys Thr Glu Ile Gln Gly His Arg Asn
  65                  70                  75                  80
 Ala Arg Ser Pro Tyr Cys Ala Gly Leu His Asp Ala Ile Ala Leu His
                  85                  90                  95    
 Gly Ala Arg Ala Gly Arg Ala Glu Pro Ala Phe Asn Cys Glu Glu Ile
             100                 105                 110        
 Pro Thr His Gln Thr Glu Gly His Phe Leu Lys His Trp Leu Leu Pro
         115                 120                 125            
 Tyr Lys Asn Val Asn Val Ile Phe Asp Lys Asp
     130                 135                



      <210> 1098
      <211> 187
      <212> PRT
      <213> Homo sapiens


      <400> 1098
 Met Thr Val Leu Phe Leu Gln Val Cys Trp Gly Arg Thr Leu Ala Gly
   1               5                  10                  15    
 Arg Gln Ala Leu Glu Pro Leu Val Ser Ala Gln Thr Gln Pro Leu Ser
              20                  25                  30        
 Gly Ala Gly Thr His Ser Ser His Lys His Arg His Leu Val Ala Tyr
          35                  40                  45            
 Ser Pro Leu Leu Pro Ser Ala Gly Pro Ile Ser Pro Leu Pro Thr Arg
      50                  55                  60                
 Gly Lys Glu Leu Ala Gly Thr Ala Val Pro Gly Leu Gly Cys Pro Cys
  65                  70                  75                  80
 Leu Ser Asp Ser Glu Ser Arg Asp Ala Leu Asp His His Ile Leu Asp
                  85                  90                  95    
 Ser Pro Gln Leu Lys Gly Ile Ser Ala Gly Phe Ser Arg Gln Glu Gly
             100                 105                 110        
 His Val Ser Pro Val Phe Val Val Leu Pro Val His Val Ser Thr Tyr
         115                 120                 125            
 Gly Asn Ile Leu Gly Phe His Ala His Ser Pro Ser Leu Pro Glu Ala
     130                 135                 140                
 Ser Glu Gln Leu Leu Val Gln Gly Arg Asn Asn Ser Asn Met Leu Asn
 145                 150                 155                 160
 Leu Gly Leu Lys Thr His Ser Lys Gly Ala Phe Ile Gly Lys Asn Ser
                 165                 170                 175    
 Thr Arg Ile Lys Leu Glu Pro Asn Leu Ile Ile
             180                 185        



      <210> 1099
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1099
 Met Gln Gln Met Val Ser Ala Ala Ser Ser Trp Ala Leu Pro Trp Ser
   1               5                  10                  15    
 Val Ser Ser Leu Leu Leu Glu Ile Cys Lys Phe His Pro Lys Ile Lys
              20                  25                  30        
 Val Glu His Ala Gly Leu Ser Ile Asp Asp Val Ala Lys Lys Leu Gly
          35                  40                  45            
 Glu Met Trp Tyr Asp Thr Ala Ala Asp Asp Lys Gln Pro
      50                  55                  60    



      <210> 1100
      <211> 417
      <212> PRT
      <213> Homo sapiens


      <400> 1100
 Met Val Val Val Met Val Met Val Val Arg Val Val Val Val Val Met
   1               5                  10                  15    
 Met Val Val Val Gly Asp Asn Gly Asp Gly Gly Asp Gly Glu Gly Asp
              20                  25                  30        
 Met Asp Leu Arg Gly Arg Cys Val Phe Leu Thr Thr Asp Gly Gln Asp
          35                  40                  45            
 Gly Pro Ser Pro Arg Phe Thr Cys Lys Pro His Ser Arg Leu Glu Pro
      50                  55                  60                
 Pro Arg Ala Gly Ile Ala Ser Arg Ser Ser Asp Gln Thr Trp Arg Met
  65                  70                  75                  80
 Val Val Ala Thr Ala Arg Gln Met Pro Val Asp Gly Lys Glu Asn Ser
                  85                  90                  95    
 Ala Ile Gln Thr Arg Asn Glu Leu Ala Trp Ser Arg Lys Tyr Ala Gly
             100                 105                 110        
 Lys Ala Leu Gly Val Thr Pro Pro Pro Ser Ala Leu Thr Pro Val Ala
         115                 120                 125            
 Leu Ile Glu Glu Pro Lys Gln Leu Asp Ile Gln Ser Leu Pro Phe Gln
     130                 135                 140                
 Pro Ile Leu Asp Arg Leu Lys Ile Lys Asp Lys Arg Gln Leu Val Pro
 145                 150                 155                 160
 Ser Tyr Leu Gly Gly Met His Thr Val Thr Glu Gly Leu Ala Gly Arg
                 165                 170                 175    
 Gln Val Leu Leu Gln Gln Val Gln Gly Gly Ala Trp Glu Ser Ala Phe
             180                 185                 190        
 Leu Thr Cys Pro Trp Ala Met Ala Ala Ala Ala Pro Gly Pro Thr Leu
         195                 200                 205            
 Thr Met Leu Gln Pro Ser Ile Ser Ala Val Gly Phe Ser Gln Met Ala
     210                 215                 220                
 Met Gly Pro His Val Gln Gly Arg Ala Ser Lys Leu Ser Ile Tyr Val
 225                 230                 235                 240
 Asn Pro Arg Arg Gln Leu Ser Thr Thr Thr Ala Met Gly Asp Glu Leu
                 245                 250                 255    
 Asn Asp Leu Tyr Cys Gly Thr Ser Arg Gln Leu Phe Ser Ser Leu Cys
             260                 265                 270        
 Asn Lys Lys Glu Pro Ala Ala Lys Ala Ala Pro Ala Ala Pro Leu Ser
         275                 280                 285            
 Ser Pro Gly Pro Pro Ala Leu Gly His Ala Gly His Gly Arg Gln Leu
     290                 295                 300                
 Leu Leu Glu Arg Ser Leu Thr Leu Phe His Leu Tyr Glu Leu Leu Lys
 305                 310                 315                 320
 Tyr Pro Arg Ala Ser Pro Gly Leu Trp Pro Pro Arg Val Trp Met Pro
                 325                 330                 335    
 His Ser Leu Thr Cys Gly Thr Phe Trp Val Pro Met Ile Met Met Arg
             340                 345                 350        
 Phe Cys Ala His Val Ala Ser Gly Leu Leu Arg Pro Pro Phe Asn Gln
         355                 360                 365            
 Val Phe Ala His Leu Ser Pro Ala Gln Gly Arg His Pro Gly Glu Asn
     370                 375                 380                
 Gly Ile Ile Val Leu Thr Ser Arg Ala Ala Val Gly Phe Asp Val Pro
 385                 390                 395                 400
 His Val Thr Val Ser Asn Arg Val Ala His Ser Gly Cys Pro Trp Leu
                 405                 410                 415    
 Arg
    



      <210> 1101
      <211> 112
      <212> PRT
      <213> Homo sapiens


      <400> 1101
 Met Ser Gln Leu Ser Leu Leu Val Arg Ala Val Val Lys Leu Leu Gln
   1               5                  10                  15    
 Pro Leu Pro His Phe Trp Glu Ala Phe Trp Ala Val Ala Lys Ala Leu
              20                  25                  30        
 Lys Asp Ala Asp Leu Gly Ala Lys Asp Pro His Pro Ala Gly Leu Ala
          35                  40                  45            
 Gly Ser Leu Ala Trp Pro Pro Asp Pro Leu Leu Leu Leu Leu Asp Pro
      50                  55                  60                
 Ser Lys Gln Asp Gln Cys Ser Ala His Ser Thr Ala Leu Arg Leu Val
  65                  70                  75                  80
 Arg Asn His Phe Tyr Ser Gln Ser Gln Arg Pro Lys Cys Thr Arg Glu
                  85                  90                  95    
 Ala Ala Ala Thr Pro Ala Leu Thr Glu Asn Leu Glu Asn Leu Glu Val
             100                 105                 110        





      <210> 1102
      <211> 446
      <212> PRT
      <213> Homo sapiens


      <400> 1102
 Met Leu Arg Pro Ala Pro Thr Leu Ile Leu Leu Leu His Ser Phe Leu
   1               5                  10                  15    
 Ala Leu Phe Val His Phe Val Gln Phe Phe Val Gln Asp Ala Lys Asn
              20                  25                  30        
 Leu Ala Thr Leu Pro Leu Ala Thr Val Gly Thr Arg Lys Lys Glu Glu
          35                  40                  45            
 Arg Val Thr Leu Arg Ile Asp Gly Ala Gly Leu Asp Pro Arg Val Asn
      50                  55                  60                
 Ile Leu Val Arg Gly Glu Val Tyr Lys Cys Ser Pro Glu Pro Val Phe
  65                  70                  75                  80
 Gln Thr Phe Tyr Asp Glu Leu Asn Val Pro Ala Pro Glu Ile Pro Gly
                  85                  90                  95    
 Lys Thr Arg Asn Leu Phe Leu Gln Leu Ala Glu His Ile Thr Gln Ser
             100                 105                 110        
 Leu Asn Ile Ser Ser Cys Cys Phe Cys Cys Cys Ser Leu Asn His Cys
         115                 120                 125            
 Val Leu Gly Ala Gly Gly Leu Lys Pro Ala Val Thr Lys Cys Leu Arg
     130                 135                 140                
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
 145                 150                 155                 160
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
                 165                 170                 175    
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
             180                 185                 190        
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
         195                 200                 205            
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
     210                 215                 220                
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
 225                 230                 235                 240
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly
                 245                 250                 255    
 Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly Leu Ala Val Thr
             260                 265                 270        
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
         275                 280                 285            
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly
     290                 295                 300                
 Leu Ala Val Thr Lys Cys Leu Cys Thr Gly Thr Gly Leu Ala Val Thr
 305                 310                 315                 320
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg
                 325                 330                 335    
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
             340                 345                 350        
 Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr
         355                 360                 365            
 Lys Cys Leu Arg Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Cys
     370                 375                 380                
 Thr Gly Thr Gly Leu Ala Val Thr Lys Cys Leu Arg Thr Gly Thr Gly
 385                 390                 395                 400
 Leu Asp Ser Leu Ala Tyr Arg Leu Pro Cys Val Ile Pro Leu Lys Gln
                 405                 410                 415    
 Gly Thr Cys Pro Gly Phe Leu Leu Met Ala Asn Leu Pro Leu Met Leu
             420                 425                 430        
 Ala Ser Leu Ser Tyr Thr Lys Phe Glu Val Phe Leu Val Ser
         435                 440                 445    



      <210> 1103
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 1103
 Met Ala Phe Thr Phe Ala Ala Phe Cys Tyr Met Leu Ala Leu Leu Leu
   1               5                  10                  15    
 Thr Ala Ala Leu Ile Phe Phe Ala Ile Trp His His Asp Leu Cys Phe
              20                  25                  30        
 Gly Glu Leu Leu Glu Gln His Thr Glu Glu Leu Val Gln Leu Ser Ala
          35                  40                  45            
 Cys Lys Lys Pro Pro Asn Glu Gly Ile Leu Ser Ser Lys Ile Leu Ser
      50                  55                  60                
 Lys Ser Ser Leu Trp Asn Leu Ile Ser Tyr Phe Lys Lys
  65                  70                  75        



      <210> 1104
      <211> 193
      <212> PRT
      <213> Homo sapiens


      <400> 1104
 Met Glu Leu Leu Val Ala Ser Lys Thr Ile Ile Val Ile Pro Thr Ile
   1               5                  10                  15    
 Ala Phe Ile Lys Ala Arg Met Ser Glu Met Ile Phe Arg Arg Ile Lys
              20                  25                  30        
 Met Pro Trp Leu Trp Leu Asp Leu Trp Tyr Leu Met Phe Lys Glu Gly
          35                  40                  45            
 Trp Glu His Lys Lys Ser Leu Gln Ile Leu His Thr Phe Thr Asn Ser
      50                  55                  60                
 Val Ile Ala Glu Arg Ala Asn Glu Met Asn Ala Asn Glu Asp Cys Arg
  65                  70                  75                  80
 Gly Asp Gly Arg Gly Ser Ala Pro Ser Lys Asn Lys Arg Arg Ala Phe
                  85                  90                  95    
 Leu Asp Leu Leu Leu Ser Val Thr Asp Asp Glu Gly Asn Arg Leu Ser
             100                 105                 110        
 His Glu Asp Ile Arg Glu Glu Val Asp Thr Phe Met Phe Glu Ala Gly
         115                 120                 125            
 Ala Gly Cys Asn Cys Pro Gly Ser Ser Cys Glu Leu Lys Val Gly Val
     130                 135                 140                
 Leu Pro Cys Ser Thr Ser Val Pro Arg Cys Phe Thr Phe Ala Leu Ser
 145                 150                 155                 160
 Cys Phe Leu Gln Leu Ala Asp Glu Met Lys Ser Glu Val Gln Gln Thr
                 165                 170                 175    
 Pro Leu Met His Leu Asp Gln Ala Ser Ala His Lys Phe Lys Glu Ser
             180                 185                 190        
 Tyr
    



      <210> 1105
      <211> 68
      <212> PRT
      <213> Homo sapiens


      <400> 1105
 Met Pro Ala Phe Thr Cys Thr Ala Val Phe Cys Val Ser Leu Pro Ala
   1               5                  10                  15    
 Ser Phe Asn Lys Thr Cys Lys Arg Pro Lys Thr Val Glu Thr Val Leu
              20                  25                  30        
 Asp Lys Asp Gln Met Pro Met Val Lys Leu Leu Leu Cys Ser Ala Ser
          35                  40                  45            
 Trp Glu Ala Pro Asn Val Ala His Lys Glu Cys Trp Gly Asn Leu Ala
      50                  55                  60                
 Gln Glu Leu Ser
  65            



      <210> 1106
      <211> 40
      <212> PRT
      <213> Homo sapiens


      <400> 1106
 Met Thr Arg Gln Ser Leu Met Gly Gln Gly Ile Phe Pro Ala Phe Leu
   1               5                  10                  15    
 Thr Val Leu Gln Ala Trp His Thr Lys Glu Ala Tyr Gly His Lys Pro
              20                  25                  30        
 Met Ile Asn Leu Thr Leu Lys Leu
          35                  40



      <210> 1107
      <211> 190
      <212> PRT
      <213> Homo sapiens


      <400> 1107
 Met Asn Gly Phe Ser Leu Gly Glu Leu Cys Trp Leu Phe Cys Cys Pro
   1               5                  10                  15    
 Pro Cys Pro Ser Arg Ile Ala Ala Lys Leu Ala Phe Leu Pro Pro Glu
              20                  25                  30        
 Pro Thr Tyr Thr Val Leu Ala Pro Glu Gln Arg Gly Ala Gly Ala Ser
          35                  40                  45            
 Ala Pro Ala Pro Ala Gln Ala Thr Ala Ala Ala Ala Ala Ala Gln Pro
      50                  55                  60                
 Ala Pro Gln Gln Pro Glu Glu Gly Ala Gly Ala Gly Pro Gly Ala Cys
  65                  70                  75                  80
 Ser Leu His Leu Ser Glu Arg Ala Asp Trp Gln Tyr Ser Gln Arg Glu
                  85                  90                  95    
 Leu Asp Ala Val Glu Val Phe Phe Ser Arg Thr Ala Arg Asp Asn Arg
             100                 105                 110        
 Leu Gly Cys Met Phe Val Arg Cys Ala Pro Ser Ser Arg Tyr Thr Leu
         115                 120                 125            
 Leu Phe Ser His Gly Asn Ala Val Asp Leu Gly Gln Met Cys Ser Phe
     130                 135                 140                
 Tyr Ile Gly Leu Gly Ser Arg Ile Asn Cys Asn Ile Phe Ser Tyr Asp
 145                 150                 155                 160
 Tyr Ser Gly Tyr Gly Val Ser Ser Gly Lys Pro Ser Glu Lys Asn Leu
                 165                 170                 175    
 Tyr Ala Asp Ile Asp Ala Ala Trp Gln Ala Leu Arg Thr Arg
             180                 185                 190



      <210> 1108
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 1108
 Met Gly Ser Phe Leu Ala Leu Ser Ala Ser Arg Leu Leu Arg Thr Leu
   1               5                  10                  15    
 Ser Ile Phe Glu Asp Gln Tyr Phe Leu Val Asp Phe Tyr Ala Pro Thr
              20                  25                  30        
 Ala Ala Val Glu Ser Met Val Glu His Leu Ser Arg Asp Ile Asp Val
          35                  40                  45            
 Ile Arg Gly Asn Ile Val Lys His Pro Leu Thr Gln Glu Leu Lys Glu
      50                  55                  60                
 Cys Glu Gly Ile Val Pro Val Pro Leu Ala Glu Lys Leu Tyr Ser Thr
  65                  70                  75                  80
 Lys Lys Arg Lys Lys Met Gly Glu Asp Glu Val Val Ser Gln Asn Ser
                  85                  90                  95    
 His Leu His Leu Phe Leu Gly Leu Leu Gly Ala Asp Trp Lys Asp Leu
             100                 105                 110        
 Thr Ser Pro Ser Pro Phe Pro Gly Gly Ala Leu His Lys Val Ser Val
         115                 120                 125            
 Thr Ile Thr Asp Asp Gly Thr Ser Ala His Lys Met Leu Gly Glu Val
     130                 135                 140                
 Pro Val Leu Gly Ile Ser Glu Lys Gln Glu Gly Ala Glu Ser Ser Gly
 145                 150                 155                 160
 Leu Cys Phe Val Phe Asn His Gly Lys Thr Gly Gly Trp Arg Asp Val
                 165                 170                 175    
 Gln Glu Met Pro Lys Ala Pro Gly Gly Pro Gly Leu Pro Ala Leu Ala
             180                 185                 190        
 Gln Arg Leu Leu Pro Leu
         195            



      <210> 1109
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 1109
 Met Asp Lys Ser Leu Leu Leu Glu Leu Pro Ile Leu Leu Cys Cys Phe
   1               5                  10                  15    
 Arg Ala Leu Ser Gly Ser Leu Ser Met Arg Asn Asp Ala Val Ile Glu
              20                  25                  30        
 Ile Ile Gln Cys Arg Met Cys His Leu Gln Phe Pro Gly Glu Lys Cys
          35                  40                  45            
 Ser Arg Gly Arg Gly Ile Cys Thr Ala Thr Thr Glu Glu Ala Cys Met
      50                  55                  60                
 Val Gly Arg Met Phe Lys Arg Asp Gly Asn Pro Trp Leu Thr Phe Met
  65                  70                  75                  80
 Gly Cys Leu Lys Asn Cys Ala Asp Val Lys Gly Ile Arg Trp Ser Val
                  85                  90                  95    
 Tyr Leu Val Asn Phe Arg Cys Cys Arg Ser His Asp Leu Cys Asn Glu
             100                 105                 110        
 Asp Leu
        



      <210> 1110
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 1110
 Met Glu Ala Cys Cys Leu Leu Gln Leu Pro Gln Arg Leu Leu Leu Leu
   1               5                  10                  15    
 Gly Ala Ala Ala Leu Thr Ala Thr Ala Leu Glu Thr Ala Asp Leu Ala
              20                  25                  30        
 Glu Leu Cys Gly Gln Thr Trp Gln Gly Asp Gly Leu Leu Leu Arg Ser
          35                  40                  45            
 His Ala Ala Ser Arg Arg Phe Tyr Phe Val Ala Pro Asp Thr Asp Cys
      50                  55                  60                
 Gly Leu Trp Val Gln Ala Ala Ala Pro Gly Asp Arg Ile Arg Phe Gln
  65                  70                  75                  80
 Phe Arg Phe Phe Leu Val Tyr Ser Leu Thr Pro Ala Pro Pro Ala Leu
                  85                  90                  95    
 Asn Thr Ser Ser Pro Ala Pro Ala Asp Pro Cys Ala Pro Gly Ser Tyr
             100                 105                 110        
 Leu Gln Phe Tyr Glu Gly Pro Pro Gly Ala Pro Arg Pro Leu Gly Ser
         115                 120                 125            
 Pro Leu Cys Gly Leu Asn Ile Pro Val Pro Val Ala Ser Ser Gly Pro
     130                 135                 140                
 Phe Leu Gly Leu Arg Leu Val Thr Arg Gly Arg Gln Pro Arg Val Asp
 145                 150                 155                 160
 Phe Val Gly Glu Val Thr Ser Phe Arg Leu Gly Glu Leu Gly Leu Lys
                 165                 170                 175    
 Ala Gly Thr Gly Pro Ser Ala Glu Ala Met Arg Asp Trp Gly His Ser
             180                 185                 190        
 Gly Gly Pro Gly Pro Cys Gly Ala Tyr Phe Arg Cys Gln Asn Gly Arg
         195                 200                 205            
 Cys Ile Pro Ser Ser Leu Val Cys Asp Pro Trp Gly Met Asp Asn Cys
     210                 215                 220                
 Gly Asp Gly Ser Asp Gln Gly Ser Trp Ser Pro Ala Asp Cys Arg Gly
 225                 230                 235                 240
 Gln Gly Pro Met Gly Arg Gln Glu Arg Gly Lys Arg Lys Cys Gly Ile
                 245                 250                 255    
 Gly Leu Gly Gln Gly Leu Glu Gly Gln Ser Ser Gln Gly Gln Asn Tyr
             260                 265                 270        
 Ala Ala Asp Asp Leu Ile Arg Arg Ile Pro Asn Asp Ala Leu Val Val
         275                 280                 285            
 Glu Thr Phe Ala Lys Trp Asp Leu Ala Trp Arg Pro Lys Thr Phe Lys
     290                 295                 300                
 Gly Asp Ile Leu Cys Leu Thr Gly Trp Cys Leu Gly Pro Trp Leu Pro
 305                 310                 315                 320
 Asp Val Ser Leu Arg Ala Leu Ser Val Thr Leu Lys Thr Tyr Phe Glu
                 325                 330                 335    
 Asn His Gln Ser Ser Leu Ile Pro Thr Leu Tyr Arg Ser Gly Asn
             340                 345                 350    



      <210> 1111
      <211> 375
      <212> PRT
      <213> Homo sapiens


      <400> 1111
 Met Glu Glu Ala Ala Val Gly Met Gln Leu Gly Pro Ile Ser Leu Ala
   1               5                  10                  15    
 Leu Ser Ser Leu Cys Leu Gly Ala Phe Pro Ser Gln Gln Ala Leu Ile
              20                  25                  30        
 Pro Gly Ser Thr Gly Thr Leu Arg Ser Pro Ala Leu Gly Gly Thr Glu
          35                  40                  45            
 Gly Val Ser Leu Trp His His Thr Cys Pro Ser Thr Leu Asn Pro Cys
      50                  55                  60                
 Gln Glu Asp Pro Gly Lys Thr Glu Glu Gly Glu Gln Met Val Thr Met
  65                  70                  75                  80
 Ala Ile Thr Asp Lys Cys Thr Glu Gln Val Lys Glu Gln Arg Gln Glu
                  85                  90                  95    
 Arg Ala Glu Met Val Gln Thr Thr Phe Thr Glu Ser Trp Trp Cys Phe
             100                 105                 110        
 Thr Ala Thr Val Leu Gly Pro Leu Ala Trp Ser Val Lys Met Gly Cys
         115                 120                 125            
 Ala His Gly Lys Trp Pro Leu Ala Gln Pro Trp Lys Gln Gln Leu Glu
     130                 135                 140                
 Glu Ala Cys Gly Leu Ser Leu Ser Thr Arg Leu Leu Leu Cys Lys Thr
 145                 150                 155                 160
 Glu Ala Arg His Asp Gln Ile Leu Thr Pro Ser Ser Gly Pro Glu Thr
                 165                 170                 175    
 Lys Pro Val Ser Ser Phe Phe Gln Ser Leu Pro Leu Leu Pro Gln Ser
             180                 185                 190        
 Thr Pro Ala Asp Leu Pro Leu Thr Arg Ala Thr Arg Gly Leu Tyr Arg
         195                 200                 205            
 Asn Gln Thr Arg Arg Gln Gly Pro Glu Leu Glu Ala Asp Val Trp Asp
     210                 215                 220                
 Asp Glu Gly Thr Asn Ile Ala Thr Ile Pro Trp Leu Arg Ser Cys Cys
 225                 230                 235                 240
 Trp Leu Val Leu Thr Ser Gln Gly Tyr Ile Asp Ser Leu Asn Asn Cys
                 245                 250                 255    
 Ala Lys Ala Thr Ser Asp Thr Ile Leu Lys Asn Leu Gln Asp Gln Ser
             260                 265                 270        
 Leu Glu Gly Cys Arg Arg Gly Glu Phe Arg Lys Ala Thr Ala Lys Asn
         275                 280                 285            
 Ser Arg Thr Ser Pro Arg Ala Pro Ser Trp Lys Pro Leu Ser Gly Pro
     290                 295                 300                
 Lys Gly Gln His Tyr Val Ser Gln Gly Gly Asp Lys Pro Ser Gly Thr
 305                 310                 315                 320
 Tyr Pro Met Gly Lys His Leu Gly Lys Gln Gln His Leu Val Leu Val
                 325                 330                 335    
 Pro Glu Glu Ser Ser Asp His Val Ala Trp Arg Ile Leu Gly Tyr Arg
             340                 345                 350        
 Asp Pro Asp Ala Gly Ser Arg Thr Pro Arg Met Ser Glu Val Ser Thr
         355                 360                 365            
 His Val Pro Arg Lys Asp Lys
     370                 375



      <210> 1112
      <211> 210
      <212> PRT
      <213> Homo sapiens


      <400> 1112
 Met Ala Glu Val Thr Leu Cys Asp Ile Gln Gly Lys Ile Arg Gln Gly
   1               5                  10                  15    
 Met Gln Leu Ala Trp Trp Leu Leu Leu Ala Ile Cys Ser Gly Ser Leu
              20                  25                  30        
 Gln Leu Pro Ser Lys Lys Phe Gly Phe His Glu Glu Gly His His Met
          35                  40                  45            
 Glu Lys Thr Ile Gln Arg Asp His Met Glu Arg Phe Lys Ser Cys Gly
      50                  55                  60                
 Ala Ala Thr Arg Glu Arg Gln Ile Ser Ile Trp Leu Gly Lys Ala Leu
  65                  70                  75                  80
 Leu Leu Leu Leu Val Asp Trp Lys Gly His Lys Asp Thr Phe Trp Gly
                  85                  90                  95    
 Lys His Pro Glu Met Ser Ser Gln Lys Thr Ser Asp Gly Tyr Gly Val
             100                 105                 110        
 Lys Thr Ser Leu Phe Trp Asn Gly Gly Ala Pro Glu Cys Asn Ala Phe
         115                 120                 125            
 Ser Glu Val Lys Tyr Lys Ser Thr Lys Pro Cys Ala Glu Leu Pro Ile
     130                 135                 140                
 Val Gln Ala Ser Glu Pro Ile His Pro Pro Leu Thr Lys Arg Lys Lys
 145                 150                 155                 160
 Gln Asn Gln Glu Cys Asp Cys Met Glu Leu Gln Glu Gly Lys Pro Val
                 165                 170                 175    
 Val Arg Asn Pro Leu Pro Ser Cys Asp Thr Phe Pro Glu Lys Ile Arg
             180                 185                 190        
 Gly Ile His Val Val Gly Ser Asn Arg Trp Ile Arg Lys Asn Val Val
         195                 200                 205            
 Leu Gly
     210



      <210> 1113
      <211> 360
      <212> PRT
      <213> Homo sapiens


      <400> 1113
 Met Leu Arg Ser Gly Ala Val Ala Gly Arg Leu Trp Leu His Leu Gly
   1               5                  10                  15    
 Val Ser Leu Ala Gln Pro Val Ser Asp Ser Ser Lys Thr Gln Gly Pro
              20                  25                  30        
 Val Ala Thr Glu Pro Asp Lys Asp Gln Gly Ser Val Val Pro Gly Leu
          35                  40                  45            
 Leu Lys Gly Gln Gly Pro Met Val Gln Glu Pro Leu Lys Lys Gln Val
      50                  55                  60                
 Ser Val Val Pro Gly Pro Pro Lys Asp Leu Gly Pro Met Ile Pro Leu
  65                  70                  75                  80
 Pro Val Lys Asp Gln Asp His Thr Val Pro Glu Pro Leu Lys Asn Glu
                  85                  90                  95    
 Ser His Cys Tyr Leu Ser Thr Ser Gln Gly Pro Ser Ala Leu Gly Pro
             100                 105                 110        
 Ser Ser Ser Lys Glu Ser Lys Ser Tyr Val Ser Ala Lys Ser Pro Val
         115                 120                 125            
 Lys Asp Glu Gly Pro Met Val Ser Ala Ser Val Lys Asp Gln Gly Pro
     130                 135                 140                
 Met Val Ser Ala Pro Val Lys Asp Gln Gly Pro Ile Val Pro Ala Pro
 145                 150                 155                 160
 Val Lys Gly Glu Gly Pro Ile Val Pro Ala Pro Val Lys Asp Glu Gly
                 165                 170                 175    
 Pro Met Val Ser Ala Pro Ile Lys Asp Gln Asp Pro Met Val Pro Glu
             180                 185                 190        
 His Pro Lys Asp Glu Ser Ala Met Ala Thr Ala Pro Ile Lys Asn Gln
         195                 200                 205            
 Gly Ser Met Val Ser Glu Pro Val Lys Asn Gln Gly Leu Val Val Ser
     210                 215                 220                
 Gly Pro Val Lys Asp Gln Asp Val Val Val Pro Glu His Ala Lys Val
 225                 230                 235                 240
 His Asp Ser Ala Val Val Ala Pro Val Lys Asn Gln Gly Pro Val Val
                 245                 250                 255    
 Pro Glu Ser Val Lys Asn Gln Asp Pro Ile Leu Pro Val Leu Val Lys
             260                 265                 270        
 Asp Gln Gly Pro Thr Val Leu Gln Pro Pro Lys Asn Gln Gly Arg Ile
         275                 280                 285            
 Val Pro Glu Pro Leu Lys Asn Gln Val Pro Ile Val Pro Val Pro Leu
     290                 295                 300                
 Lys Asp Gln Asp Pro Leu Val Pro Val Pro Ala Lys Asp Gln Gly Pro
 305                 310                 315                 320
 Ala Val Pro Glu Pro Leu Lys Thr Gln Gly Pro Arg Asp Pro Gln Leu
                 325                 330                 335    
 Pro Thr Val Ser Pro Leu Pro Arg Val Met Ile Pro Thr Ala Pro His
             340                 345                 350        
 Thr Glu Tyr Ile Glu Ser Ser Pro
         355                 360



      <210> 1114
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1114
 Met Met Arg Arg Gly Leu Pro Leu Ala Gly Trp Val Phe Gly Arg Pro
   1               5                  10                  15    
 Phe His Pro His Cys Leu Leu Leu Ala Arg Asn Ile Ala Asp Pro Gln
              20                  25                  30        
 Asp Ala Ala Arg Arg Glu Asp Leu Ser Gln Lys Pro Thr Ser Lys Met
          35                  40                  45            
 Gly Lys Val Arg Pro Leu Leu Ser Gly Gly Ile Cys Glu Ile Lys Ile
      50                  55                  60                
 Gln Asn Val Gly Leu Arg Pro Glu Ser Val Thr Lys Asp Arg Gly Ser
  65                  70                  75                  80
 Phe Thr Glu Thr Gln Arg Glu Lys Glu Lys Ser Leu Lys His Phe
                  85                  90                  95



      <210> 1115
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1115
 Met Pro Gly Phe Ser Thr Thr Arg Leu Pro Arg Ala Cys Ala Gly Val
   1               5                  10                  15    
 Arg Arg Leu Pro Thr Ile Thr Leu Thr Phe Thr Phe Pro Ile Leu Ala
              20                  25                  30        
 Tyr Leu Ala Arg Ile Gln Val Leu Leu His Val Ser Arg Gln Pro Asn
          35                  40                  45            
 Thr Leu Leu Ser Asp Gly Asp Glu Gly Gln Lys His Leu Gly Ile Ser
      50                  55                  60                
 Gly Ser Asn Ala Gly Ser Gly Lys Met Leu Gln Gly Gly Asp Cys Gln
  65                  70                  75                  80
 Val Pro Glu Pro Gly Leu Thr Gly Ser Ala Gln Asp Glu Ala Ala Thr
                  85                  90                  95    
 Gly Asn Pro Asn Val Lys
             100        



      <210> 1116
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1116
 Met Val Val Phe Val Gly Arg Arg Leu Pro Ala Leu Leu Gly Leu Phe
   1               5                  10                  15    
 Lys Lys Lys Gly Val Ile Ala Leu Phe Cys Arg Gln Tyr Asp Ile Ile
              20                  25                  30        
 Lys Asp Asn Glu Pro Asn Asn Asn Lys Glu Lys Thr Lys Ser Ala Ser
          35                  40                  45            
 Glu Thr Ser Thr Pro Glu His Gln Gly Gly Gly Leu Leu Arg Ser Lys
      50                  55                  60                
 Pro Cys Lys Lys Ala Ile His Asn
  65                  70        



      <210> 1117
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1117
 Met Gly Val Val Pro Leu Ala Ser Lys Ile Leu Ser Cys Leu Pro Leu
   1               5                  10                  15    
 Gly Arg Gly Ala Cys Lys Pro Arg Thr Tyr Leu Ile Gly Leu Pro Lys
              20                  25                  30        
 Pro Asp Val Lys Gly Arg Leu Pro Gln Gly Leu Asp Gly Leu Trp Arg
          35                  40                  45            
 Glu Gln Ala Pro Ala Ser Asp Ser Gln Ala Thr Tyr Phe Trp Lys Gly
      50                  55                  60                
 Pro Met Leu Arg Val Glu Ile Pro Ser Val Asp Ala Arg Gly Arg Leu
  65                  70                  75                  80
 Glu Asp Met Gly Ser Gly Ser Ala Cys Gly Trp Ser Gln Cys Gly Arg
                  85                  90                  95    
 Cys Arg Asp Gly Arg Val Gln Met Ser Cys Arg Trp Gly Asn Thr Gly
             100                 105                 110        
 Tyr Leu Arg Ser Glu Val Gly Thr Ser Leu Ser Asn His
         115                 120                 125



      <210> 1118
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1118
 Met Lys Leu Cys Val Thr Val Leu Ser Leu Leu Val Leu Val Ala Ala
   1               5                  10                  15    
 Phe Cys Ser Leu Ala Leu Ser Ala Pro Ile Lys Leu Gly Ala Tyr Gly
              20                  25                  30        
 Gly Gln Val Ile Asn Gly Val Leu Ala Gln Val Gln Leu Thr Val Gly
          35                  40                  45            
 Pro Val Gly Pro Trp Ile His Pro Val Val Ile Ser Pro Met Thr Glu
      50                  55                  60                
 Cys Val Ile Gly Ile Asp Ile Phe Asn Ser Trp Gln Asn Pro Tyr Ile
  65                  70                  75                  80
 Gly Ser Leu Thr Gly Ile Asp Leu Ala Asn Ala Phe Phe Ser Ile Pro
                  85                  90                  95    
 Val His Lys Ala His Gln Lys Gln Phe Ala Phe Ser Trp Gln Gly Gln
             100                 105                 110        
 Gln Tyr Thr Phe Thr Val Leu Pro His Gly Tyr Ile Asn Ser Pro Ala
         115                 120                 125            
 Leu Arg His Asn Leu Ile Gln Arg Asp Leu Asp His Phe Leu Leu Leu
     130                 135                 140                
 Lys Asp Ile Thr Leu Val His Tyr Asn Asp Ile Met Met Ile Gly Ser
 145                 150                 155                 160
 Ser Glu Gln Lys Val Ala Asn Thr Leu Asp Leu Leu Pro Pro Leu Ser
                 165                 170                 175    
 Pro Pro Asn Gly Pro Met Asn Lys Val Ala Met Val Ala Gly Met Glu
             180                 185                 190        
 Ala Thr His Gly Phe Ser Lys Ile Asp Phe His Ser Pro Arg Leu Thr
         195                 200                 205            
 Trp Leu Trp Pro Leu Leu Ser Val Gln Phe Ala Asn Arg Arg Asp Gln
     210                 215                 220                
 Tyr
 225



      <210> 1119
      <211> 216
      <212> PRT
      <213> Homo sapiens


      <400> 1119
 Met Asp Ile Met Thr Lys Ser Glu Asp Ser Gly Gln Thr Ala Trp Leu
   1               5                  10                  15    
 Gln Ile Thr Ala Leu Leu Pro Met Thr Trp Val Thr Trp Thr Phe Leu
              20                  25                  30        
 Glu Ser Asn Val Cys Ile Pro Arg Asn Gln Gly Gly Pro Glu Ala Leu
          35                  40                  45            
 Ala Thr Gly Leu Arg Val Leu Val Thr Phe Met Asn Val Asp Trp Glu
      50                  55                  60                
 Thr Glu Gln Asp Ser Val Lys Lys Glu Lys Glu Arg Lys Lys Lys Lys
  65                  70                  75                  80
 Glu Arg Lys Lys Lys Lys Glu Arg Lys Lys Gly Arg Lys Glu Gly Arg
                  85                  90                  95    
 Lys Glu Arg Glu Lys Lys Lys Lys Lys Glu Lys Glu Lys Lys Lys Lys
             100                 105                 110        
 Lys Lys Lys Glu Lys Glu Lys Lys Lys Lys Lys Lys Lys Lys Lys Arg
         115                 120                 125            
 Arg Lys Glu Gly Arg Lys Glu Gly Arg Glu Gly Arg Lys Glu Ser Arg
     130                 135                 140                
 Lys Glu Leu Pro Glu Thr Ala Glu Phe Ile Lys Asn Arg Gly Leu Ile
 145                 150                 155                 160
 Asp Ser Gln Phe Ser Met Ala Gly Glu Thr Ser Gly Asn Leu Gln Ser
                 165                 170                 175    
 Trp Arg Lys Arg Lys Gln Ile His Pro Ser Ser Cys Gly Ser Arg Lys
             180                 185                 190        
 Glu Lys Asn Glu Ser Arg Ala Lys Gly Glu Ala Pro Tyr Lys Thr Ile
         195                 200                 205            
 Arg Ser Cys Glu Asn Ser Leu Ser
     210                 215    



      <210> 1120
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 1120
 Met Ala Ser Arg Arg Gly Leu Arg Trp Cys Cys Leu Ala Leu Pro Gly
   1               5                  10                  15    
 Arg Arg Val Ser Arg Leu Arg Ser Pro Arg Pro Pro Ala Leu Phe Pro
              20                  25                  30        
 Pro Arg Cys Cys Pro Phe Cys Val Cys Val Leu Ala Ser Ser Leu Arg
          35                  40                  45            
 Ala Val Cys Ala Gly Gly Arg Leu Leu Val Arg Gly Ala Ala Ala Cys
      50                  55                  60                
 Cys Ser Val Arg Gly Ala Leu Arg Ser Val Leu Pro Gly Ala Ala Cys
  65                  70                  75                  80
 Ala Cys Ala Asn Leu Arg Asn Ala Gly Leu Ala Leu Ser Asn Cys Val
                  85                  90                  95    
 Asn Gly Phe Glu Asp Gln Glu Pro Gly Pro Gly Asp Gly Thr Arg Val
             100                 105                 110        
 Leu Leu Trp Ser Arg Val Gln Arg Thr Arg Ser Thr Pro Ala Arg Asp
         115                 120                 125            
 Arg Ser Thr Arg Arg Arg Lys Gly Lys Gly Gly Glu Pro Asn His Pro
     130                 135                 140                
 Arg Lys Asp Val Gln Gln Lys Asn Val Gln Thr Thr
 145                 150                 155    



      <210> 1121
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 1121
 Met Ile Gly Phe Leu Val Val Pro Ser Phe Cys Leu Met Asp Ser Cys
   1               5                  10                  15    
 Leu Leu Ala Val Ser Ser His Gly Arg Glu Gln Lys Asp Gln Ala Ser
              20                  25                  30        
 Pro Leu Leu Pro Leu Leu Glu Gly His Arg Pro His His Glu Ala Leu
          35                  40                  45            
 His Pro Asp Gln Cys Pro Lys Ala Pro Pro Phe Asn Asn Ile Pro Leu
      50                  55                  60                
 Glu Thr Ser Val Lys Gly Glu Asn Val Tyr Phe Lys Val Tyr Phe Gln
  65                  70                  75                  80
 Leu Leu Lys Ile Ala Lys Lys Pro Phe Ser Trp Asn His His Leu Pro
                  85                  90                  95    
 Val Ile Arg Gln Asn Asp Lys His Lys Gly Lys Glu Glu Arg Tyr Leu
             100                 105                 110        
 Val Cys Ser Pro Ser Leu Leu Glu Asn Met Glu Leu Phe Val Trp Pro
         115                 120                 125            
 Gly Val Thr Met Ala Lys Leu Glu Ala Phe Thr Met Phe Pro Ser Val
     130                 135                 140                
 Leu Leu Ala Leu Leu Gln Met Asn Lys Gly Met Ile Leu Asp Lys Arg
 145                 150                 155                 160
 Ile Asn Val Gly Ile Glu His Ile Lys His Ser Gly Ser Gln Asp Ser
                 165                 170                 175    
 Phe Leu Lys His Val Lys Glu Asn Asp Gln Lys Lys Lys Pro Lys Arg
             180                 185                 190        
 Arg Val Pro Gly Leu Asn
         195            



      <210> 1122
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1122
 Met Arg Pro Leu Leu Leu Leu Ala Leu Leu Gly Trp Leu Leu Leu Ala
   1               5                  10                  15    
 Glu Ala Lys Gly Asp Ala Lys Pro Glu Ala Leu Pro Gly Met Gly His
              20                  25                  30        
 Leu Gln Gly Cys Pro Glu Lys Gly Ile Asp Cys Gly Gln Ser Gln Gln
          35                  40                  45            
 Ser Gln Ala Glu Val Ala Val Leu Ser Met Ala Phe Ser Ser Phe Ser
      50                  55                  60                
 Leu Pro Ser Trp Arg Thr
  65                  70



      <210> 1123
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 1123
 Met Trp Ala Gly Val Cys Ala Tyr Arg Val Val Glu Thr Leu Ser Val
   1               5                  10                  15    
 Ala Pro Ala Leu Thr Asn Cys Thr Lys His Ser Asn Phe Glu Asn Lys
              20                  25                  30        
 Arg Gly Asn Glu Asn Thr Gln Thr Cys Gln Tyr Thr Ile Gln Tyr Tyr
          35                  40                  45            
 Met Asn Asn Arg Asn Ser Ile Met Lys Ser Asp Phe Ser Thr Leu Lys
      50                  55                  60                
 Glu Ser Glu Thr Ala Phe Gln Lys Thr Gln Leu Leu Cys Glu Cys Ser
  65                  70                  75                  80
 Thr Arg Gly Ser Lys Val Asn Arg Asn Phe Ile Ser Trp
                  85                  90            



      <210> 1124
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1124
 Met Leu Ala Arg Gly Lys Glu Ser Ala Phe Pro Tyr Arg Leu Ile Val
   1               5                  10                  15    
 Phe Phe Ile Phe Leu Ile Leu His Lys Ser Asp Arg Thr Asp Ser Val
              20                  25                  30        
 Asp Ser Thr Leu Val Pro Gly Phe Ile Arg Asp Ile Ile Tyr Gln Val
          35                  40                  45            
 Leu Gln Cys Thr Thr Ala Arg Gln Ile Leu Cys Ser Phe Asn Val Lys
      50                  55                  60                
 Arg Glu Ser Gln Gly Asp Phe Gly Arg Thr Gln Lys Glu Glu Phe Phe
  65                  70                  75                  80
 Thr Ser Asp Gly His Ser Leu Thr Asp Arg Ala Gly Val Lys Leu Gln
                  85                  90                  95    
 Asp Tyr Leu Phe Pro Gly Ala Pro Asp Glu Ser Gly Gln Glu Glu Gly
             100                 105                 110        
 Gly Gly Gly Ala Ser Val Ser Gly Trp Gly Ser Glu Val Arg Leu His
         115                 120                 125            
 Ala Leu Lys Glu Ser Phe Gln Val Ser Ser Trp Leu Arg Leu Lys Thr
     130                 135                 140                
 Pro Ala Ser Val Leu Ile
 145                 150



      <210> 1125
      <211> 149
      <212> PRT
      <213> Homo sapiens


      <400> 1125
 Met Ala Ala Ala Ala Val Ile Leu Arg Ile Leu Leu Leu Leu Leu Leu
   1               5                  10                  15    
 Leu Phe Gln Tyr Ser Leu Arg Pro Gln Thr Lys Met Pro Val Gln Ser
              20                  25                  30        
 Asp Pro Leu Pro Tyr Ala Ala Pro Cys Gly Ile Cys Thr Pro Asp Leu
          35                  40                  45            
 Val Val Phe Leu Ala Cys Ala Asn Gln Arg Leu Lys Glu Arg Leu Leu
      50                  55                  60                
 Lys Arg Ala Glu Gln Gln Gly Arg Pro Asp Asp Asn Val Lys Ala Thr
  65                  70                  75                  80
 Gln Arg Arg Leu Met Asn Phe Lys Gln Asn Ala Ala Pro Leu Val Lys
                  85                  90                  95    
 Tyr Phe Gln Glu Lys Gly Leu Ile Met Thr Leu Ser Val Asp Met Pro
             100                 105                 110        
 Asp His Asp Ile Phe Pro Tyr Pro Gly Tyr His Ser Arg His Cys Lys
         115                 120                 125            
 Glu Tyr Lys Asp Asp Val Glu Pro Asp Pro Val Phe Arg Glu Phe Val
     130                 135                 140                
 Thr Gln Ala Gln Arg
 145                



      <210> 1126
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 1126
 Met Leu Leu Phe Val His Leu Trp Leu Cys His Gln Gly Asp Leu Thr
   1               5                  10                  15    
 Ser Ala Leu Asp Ser Val Glu Leu Asp Ile Leu Cys Asn Glu Glu Ile
              20                  25                  30        
 Leu Gly Lys Asp His Thr Leu Lys Phe Val Val Val Thr Arg Trp Arg
          35                  40                  45            
 Phe Lys Gly Ala Gly Asn Gly His Val Ala Lys Ala Leu Gln Glu Arg
      50                  55                  60                
 Ala Glu Val Ser Leu Thr Leu Gln Val Ser Phe Ala Pro Asn Ser Ala
  65                  70                  75                  80
 Ser Glu Glu Arg Ala Ala Val
                  85        



      <210> 1127
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 1127
 Met Ser Leu Lys Met Leu Ile Ala Leu Arg Glu Arg Leu Leu Leu Ser
   1               5                  10                  15    
 Leu Leu Pro Ala His Ile Ala Met Glu Met Lys Ala Glu Ile Ile Gln
              20                  25                  30        
 Arg Leu Gln Gly Pro Lys Ala Gly Gln Met Glu Asn Thr Asn Asn Phe
          35                  40                  45            
 His Asn Leu Tyr Val Lys Arg His Thr Asn Val Arg Tyr Asp Ala Met
      50                  55                  60                
 Leu Ala Pro Trp Leu Val Trp Glu Ser Ala
  65                  70                



      <210> 1128
      <211> 242
      <212> PRT
      <213> Homo sapiens


      <400> 1128
 Met Pro Ala Ser Ser Thr Val His Val Leu Gln Leu Leu Arg Glu Leu
   1               5                  10                  15    
 Leu Ala Phe Val Leu Leu Ser Tyr Thr Val Leu Ser Arg Gly Ala Ala
              20                  25                  30        
 Ala Gly Arg Leu Asp His Leu Leu Pro Gly Asn Ser Leu Gln Ala Leu
          35                  40                  45            
 Ala Arg Thr Glu Ser Pro Pro Thr Arg Gln Arg His Gly Ala Arg Leu
      50                  55                  60                
 Ser Ser Ala Pro Asp Pro Pro Pro Arg Pro Gln Ala Leu His Met Pro
  65                  70                  75                  80
 Arg Pro Ala Arg Lys Phe Arg Arg Leu Val Ala Leu Arg Gly Arg Tyr
                  85                  90                  95    
 Ser Leu Cys Pro Lys Pro Arg Pro Leu Ser Pro Cys Leu Pro Asn Pro
             100                 105                 110        
 Asp Cys Phe Leu Gly Trp Gly Arg Gly Tyr Gly Ala Arg Arg Ser Gln
         115                 120                 125            
 Val Glu Ala Val Pro Arg Ser Ala Leu Thr Lys Leu Arg His Phe Arg
     130                 135                 140                
 Arg Val Arg Leu Ala Ser Ala Arg Cys Thr Met Ala Ala Leu Lys Ser
 145                 150                 155                 160
 Trp Leu Ser Arg Ser Val Thr Ser Phe Phe Arg Tyr Arg Cys Gly Arg
                 165                 170                 175    
 Val Glu Gly Thr Gly Pro Glu Gly Gly Thr Asp Ala Asp Ser Ala Val
             180                 185                 190        
 Ala Arg Pro Thr Ala Pro Ala Phe Leu Thr Arg Ser Ser Leu Val Arg
         195                 200                 205            
 Pro Ala Gly Ser Arg Arg Leu Ala Pro Val Gly Arg Thr Glu Asp Ser
     210                 215                 220                
 Pro Ala Ser Ala Pro Trp Val Lys Pro Gly Phe Leu Phe Ser Ser Ser
 225                 230                 235                 240
 Ile Phe
        



      <210> 1129
      <211> 179
      <212> PRT
      <213> Homo sapiens


      <400> 1129
 Met Lys Leu Thr Val Met Gln Ile Pro Gln Cys Phe Ser Phe Ser Leu
   1               5                  10                  15    
 Val Met Trp Gln Asn Trp Tyr Ser Val Glu Thr Thr Gln Gly Asn Gly
              20                  25                  30        
 Thr Glu Phe Pro Leu Gly Lys Gly Glu Cys Ala Glu Glu Thr Ser Ile
          35                  40                  45            
 Ser Met Gly Ser Pro Thr Thr Glu Ser Asp Leu Arg Glu Lys Thr Pro
      50                  55                  60                
 Glu Asp Asn Ser Arg Val Phe Gln Tyr Gln Gly Tyr Gly Ile Val Ser
  65                  70                  75                  80
 Ile Val Thr Asp Phe Ala Leu Gln Leu Ile Arg Gly Leu Arg Leu Arg
                  85                  90                  95    
 Ser Val Phe Arg Arg Leu Thr Gly His Leu Glu Leu Cys Val Gln Ser
             100                 105                 110        
 Tyr Ala Arg Lys Asn Glu Ala Tyr Asn Thr Arg Tyr Lys His Tyr Glu
         115                 120                 125            
 Gln Val Lys Ser Lys Ser Gln Glu Arg Glu Val Asn Thr Asp Lys Thr
     130                 135                 140                
 Cys Ile Ala Met Ser Leu Asp Met Lys Lys Ser Leu Val His Gly Tyr
 145                 150                 155                 160
 Glu Glu Ile Leu Asn Ile His Leu Leu Ile Tyr Phe Ile Ser Cys Lys
                 165                 170                 175    
 Leu Phe Leu
            



      <210> 1130
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 1130
 Met Trp Ser Leu Lys Leu Val His Phe Ile Trp Val Ala His Thr Ser
   1               5                  10                  15    
 Phe Cys Asn Gln Leu Pro Thr Ile Trp Cys Arg Val Gly Thr Asp Thr
              20                  25                  30        
 Ala Gly Ser Phe Leu His Ala Ala Phe Phe Leu Leu Ala Phe Ser Ile
          35                  40                  45            
 Glu Gly Ala Gly Met Met Ser Asp Gln Ser Ala Arg Pro Ser Leu Gln
      50                  55                  60                
 Pro Tyr Asn Gln Thr Ile Arg Ser Lys Gly Ser Ser Leu Leu Pro Val
  65                  70                  75                  80
 Arg Ser Arg Trp Val Trp Gln Leu Glu Val Thr Cys Glu Val Asp Gly
                  85                  90                  95    
 Thr Thr Gly Trp Arg Glu His Arg Phe Leu Asn Leu Phe Leu Glu Lys
             100                 105                 110        
 Ala His Leu Leu Thr Arg Asn Pro Ile
         115                 120    



      <210> 1131
      <211> 238
      <212> PRT
      <213> Homo sapiens


      <400> 1131
 Met Ala Val Leu Ala Ala Asp Pro Pro Arg Phe Gln Ser Thr Lys Ser
   1               5                  10                  15    
 Arg Tyr Ser Ala Val Trp Leu Leu Leu Ala Phe Ser Leu Asp Gln Leu
              20                  25                  30        
 Ser Ser Thr Ser Ser Cys Thr Ser His Thr Ile Thr Lys Tyr Asn Lys
          35                  40                  45            
 Ser Ile Thr Cys His His Thr Thr Ile Leu Gly Ser Pro Ala Met Thr
      50                  55                  60                
 Thr Ser Val Pro Ile Asn Gln Ser Asn Pro Gly Tyr Lys Met Leu Val
  65                  70                  75                  80
 Pro Gln Thr Arg Asp Ala Glu Trp Glu Asp Glu Arg Lys Trp Ala Arg
                  85                  90                  95    
 Arg Gly Pro Thr Ala Asn Pro Ala Pro Gln Leu Pro Ala Thr Ser Ser
             100                 105                 110        
 Leu Cys Thr Gly Lys Lys Arg Asn Ser Thr His Phe Ser Ala Asn Thr
         115                 120                 125            
 Ser Asp Pro Leu Leu Ala Asn Asp Leu Pro Asn Phe Ser Pro Ala Ala
     130                 135                 140                
 Ser Ala Ser Gln Cys Ser Gly Pro Arg Ser Leu Thr Gln Ala Ala Ala
 145                 150                 155                 160
 Gly Ser Phe Gln Arg Pro Val His Ala Pro Glu Thr Pro Arg Gly Arg
                 165                 170                 175    
 Arg Gly Arg Gly Tyr Met Gly Asn Gly Ser Cys Val Thr Thr Ser Thr
             180                 185                 190        
 Leu Ala Arg Gln Arg Leu Asp Glu Glu Pro Pro Pro Asp Gln Phe Val
         195                 200                 205            
 Asn Ile Pro Ala Val Thr Lys Asn Met Ser Trp Ile Arg Arg Arg Arg
     210                 215                 220                
 Gly Ala Gly Arg Met Ile Phe Lys Gln Lys Leu Asn Val Gln
 225                 230                 235            



      <210> 1132
      <211> 174
      <212> PRT
      <213> Homo sapiens


      <400> 1132
 Met Ala Glu Leu Ala Val Leu Thr Leu Phe Leu Ser Val Leu Cys Phe
   1               5                  10                  15    
 Ser Arg Met Cys Met Ser Gln Phe Asp Ile Phe Tyr Tyr Arg Lys Lys
              20                  25                  30        
 Ala Thr Ala Tyr Thr Lys Gln Arg Arg Asp Gly Lys Gly Thr Tyr Arg
          35                  40                  45            
 Ala Lys Gly Lys Tyr Thr Arg Ile Asn Thr Ala Phe Glu Ser Lys Pro
      50                  55                  60                
 Glu Gln Cys Leu Ala Ala Arg Pro Ile Ala Pro Glu Ser Asn Arg Arg
  65                  70                  75                  80
 Ser Ser Ala Trp Pro Pro Gly Thr Arg Lys Asn Gly Lys Ala Pro Gly
                  85                  90                  95    
 Tyr Arg Tyr Phe Pro Ala Gly Asn Ser Glu Phe Gly Cys Glu Cys Ala
             100                 105                 110        
 Trp Lys Gly Glu Gly Ser Gly Ser Pro Arg Asn Leu Ser Arg Pro Ser
         115                 120                 125            
 Phe Ser Leu Thr Phe Pro Val Val Phe Phe Lys Gln Thr His Thr Lys
     130                 135                 140                
 Leu Ser Val Leu Trp Lys Leu Pro Val Ala Thr Lys Cys Met Gly Asn
 145                 150                 155                 160
 Glu Arg Ser His Leu Ala His Asp Val Ala Leu Leu Thr Pro
                 165                 170                



      <210> 1133
      <211> 44
      <212> PRT
      <213> Homo sapiens


      <400> 1133
 Met Val Phe Phe Gln Ser Val Val Asn Ser Phe Ser Met Phe Thr Leu
   1               5                  10                  15    
 Asn Leu Leu Ser Trp Ser Cys Leu Glu Val Leu Asp Val Asn Lys Glu
              20                  25                  30        
 Glu Lys Glu Tyr Ala Val Thr Gly Ala Ser Tyr Ser
          35                  40                



      <210> 1134
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1134
 Met Ala Trp Met Ala Leu Leu Tyr Pro Thr Leu Pro Ser Thr Ser Leu
   1               5                  10                  15    
 Tyr Thr Lys Val Ala Pro Gly Thr Gln Phe Ser Ser Leu Gly Val Ala
              20                  25                  30        
 Thr Lys Asp Pro Ser Lys Leu Lys Ala Gly Lys Thr Lys Lys His Thr
          35                  40                  45            
 Leu Arg Gly Gln Ser Thr Lys Leu Ala Lys Leu Ala Ala Gly Leu Pro
      50                  55                  60                
 Ser Phe Pro Ser Ala Thr Gln Leu Ile Tyr Ala Leu Gly Val Ala Glu
  65                  70                  75                  80
 Gln Tyr Arg Gly Arg Asp Gln Val Gly Thr Arg Ser Leu Val Tyr Pro
                  85                  90                  95    
 Glu Cys Leu Pro Trp Thr Val Asn Leu Thr Asp Ile Lys Gln Cys Val
             100                 105                 110        
 Thr Ala Glu Ser Leu Leu Lys
         115                



      <210> 1135
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1135
 Met Val Ser Arg Ala Cys Phe Pro Phe Ile Phe Cys Leu Asp Cys Val
   1               5                  10                  15    
 Phe Glu Leu Tyr Gln Phe Val Glu Lys Gln Arg Asp Val Lys Asp Ser
              20                  25                  30        
 Asn Leu Arg Phe Ile Ser Leu Ser Arg Asp Asn Thr Leu Asn Pro Gly
          35                  40                  45            
 Ile Phe His Asp Asn Ala Asn Thr Ser Cys Ile Asn Gln Thr Lys Ile
      50                  55                  60                
 Glu Gln Glu Phe Ile Ile Lys Asn Lys Gln Lys Lys Ser Thr Ser His
  65                  70                  75                  80





      <210> 1136
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1136
 Met Lys Val Leu Ala Phe Asn Ile Thr Tyr Glu Val Pro Val Val Leu
   1               5                  10                  15    
 Leu Leu Val Arg Val Ala Glu Val Ser Asp Thr Val Glu Gly Trp Leu
              20                  25                  30        
 Leu Val Thr Ala Glu Ala Val Ser Glu Ala Cys Ser Glu Val Asp Gly
          35                  40                  45            
 Phe Glu Leu Leu Met Glu Ala Leu Val Ala Cys Asp Ser Ile Leu Ala
      50                  55                  60                
 Glu Val Asn Trp Glu Ser Ile Arg Ile Phe Phe Ile Glu Leu Ser Leu
  65                  70                  75                  80
 Gly Trp Thr Glu Ile Thr Tyr Phe Val
                  85                



      <210> 1137
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1137
 Met Trp Ile Val Cys Pro Phe Leu Phe Glu Cys Lys Leu Pro Arg Gly
   1               5                  10                  15    
 Lys Thr Trp Leu Val Phe Leu Thr Ala Thr Phe Leu Glu Cys Ser Arg
              20                  25                  30        
 His Thr Asn Arg Lys Gln Ser Leu Glu Ile Cys Ala Asp Lys Ser Lys
          35                  40                  45            
 Lys Glu Lys Ser Gln Arg Asp Asn Glu Phe Leu Ser Tyr Ile Ser Glu
      50                  55                  60                
 His Leu Pro Asn Ala Arg Asp Asn Ala Gly Cys Cys Ala Val Asn Asp
  65                  70                  75                  80
 Lys Glu Asp Thr Val Leu Pro Leu Lys Ser Asp Gly Ser Asn Cys Asp
                  85                  90                  95    
 Cys Leu Pro Ala Arg Met Leu Leu Glu Asn Arg Gly Glu Glu Leu Ala
             100                 105                 110        
 Ser Ala Trp Arg Asn Arg Ser Arg Glu His Trp Arg Leu Gln Val Lys
         115                 120                 125            
 Asn Glu
     130



      <210> 1138
      <211> 44
      <212> PRT
      <213> Homo sapiens


      <400> 1138
 Met Glu Thr Val Leu Thr Thr Arg Lys Leu Gly Trp Gly Leu Leu Leu
   1               5                  10                  15    
 Phe Pro Pro Ser Gln Leu Gln Gln Gly Gln Ala Gly Lys His Glu Leu
              20                  25                  30        
 Asn Gln Phe Ile Ser Asn Cys Ala Ser Ser Ser Lys
          35                  40                



      <210> 1139
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 1139
 Met Ser Ala Met Ala Ile Val Ala Ile Cys Met Val Leu Tyr Thr Asn
   1               5                  10                  15    
 Arg Lys Glu Gly Ala Ser Thr Leu Val Thr Asp Gly Glu Arg Ser Ser
              20                  25                  30        
 Gln Leu Leu Thr Phe Thr Val Leu Ile Arg Ser Val Leu Ser Leu Pro
          35                  40                  45            
 Ile Met Arg Gly Thr Ser Trp Thr Thr Phe Gln Pro Ile Gln
      50                  55                  60        



      <210> 1140
      <211> 112
      <212> PRT
      <213> Homo sapiens


      <400> 1140
 Met Ala Gln Arg Cys Val Cys Val Leu Ala Leu Val Ala Met Leu Leu
   1               5                  10                  15    
 Leu Val Phe Pro Thr Val Ser Arg Ser Met Gly Pro Arg Ser Gly Glu
              20                  25                  30        
 His Gln Arg Ala Ser Arg Ile Pro Ser Gln Phe Ser Lys Glu Glu Arg
          35                  40                  45            
 Val Ala Met Lys Glu Ala Leu Lys Gly Gln Pro Val Thr Pro Arg Phe
      50                  55                  60                
 Arg Arg Lys Ala Ser Ala Thr Ala Ala Gly Ala Pro Thr Arg Thr Pro
  65                  70                  75                  80
 Ala Arg Pro Gln His Pro Ser Gln His Ile Val Pro Leu Ser Gly Asp
                  85                  90                  95    
 Ala Thr Leu Pro Pro Tyr Leu Ala Pro Gly Thr Leu Val Cys Pro Ala
             100                 105                 110        





      <210> 1141
      <211> 304
      <212> PRT
      <213> Homo sapiens


      <400> 1141
 Met Lys Lys Ile Pro Leu Ser Ala Ile Thr Leu Thr Phe Leu Ser Gly
   1               5                  10                  15    
 Met Leu Gln Asp Pro Asp Asp Arg Pro Gly Leu Gly Glu Pro Ala Arg
              20                  25                  30        
 Ser Val Asn Gly Ser Asp Gly Gly Leu Ser Cys Leu Glu Asp Leu Asp
          35                  40                  45            
 Thr Gly Ile Gly Glu Pro Gly Gln Asp Ser Thr Ala Phe Met Ile Pro
      50                  55                  60                
 Gly His Arg Asp Arg Glu Pro Gln Gln His Leu Phe Gln Asp Asp Pro
  65                  70                  75                  80
 Ala Asn Cys Lys Val Ala Phe Gly Leu Phe Leu Ser Asn Cys Gln Thr
                  85                  90                  95    
 Leu Ser Gln Gly Glu Glu Glu Ala Asn Gly Arg Ala Gly Val Leu Pro
             100                 105                 110        
 Thr Arg Arg Pro Asn Gln Asp Pro Pro Thr Thr Arg Ala Asp Cys Glu
         115                 120                 125            
 Pro Thr Arg Val Asp Asp Asp Lys Gly Lys Asp Leu Tyr Ala Glu Pro
     130                 135                 140                
 Leu Leu Arg Ser Glu Pro His Arg Glu Ile Pro Ala Thr Val Pro Glu
 145                 150                 155                 160
 Pro Phe Gly Leu Gly Leu Lys Pro Ser Asn Pro Ser Pro Glu Ser Thr
                 165                 170                 175    
 Ser Glu Ser Asn Gly Pro Leu Gly Cys Lys Pro Leu Lys Ala Ala Val
             180                 185                 190        
 Tyr Gly Thr Ala Phe Val Leu Cys Ala Leu Tyr Ser Thr Cys His Leu
         195                 200                 205            
 Leu Gly Ala Arg Glu Met Ala Val Ala Asn Ala Arg Ser Pro Arg Arg
     210                 215                 220                
 His Pro Phe Leu Ser Gly His Arg Gly Ala Pro Gly Asn Ala Ala Ser
 225                 230                 235                 240
 Asp Ala Cys Asp Ser Val Thr Arg Leu Asp Phe Asn Pro Lys Arg Ile
                 245                 250                 255    
 Lys Gln Pro Phe Arg Pro Thr Val Asn Gln Pro Gln Lys Met Val Thr
             260                 265                 270        
 Pro Gln Gly Ile Ala Ala Leu Asn Glu Val Asp Arg Ile Ser Phe Leu
         275                 280                 285            
 Trp Glu His Ile Arg Asn Ala Gln Ser Gln Ala Ser Pro Gln Ile Tyr
     290                 295                 300                





      <210> 1142
      <211> 207
      <212> PRT
      <213> Homo sapiens


      <400> 1142
 Met Ile Val Val Leu Pro Ser Arg Met His Tyr Leu Cys Ile Arg Leu
   1               5                  10                  15    
 Ala Pro Ser Ser Asn Phe Leu Ser Leu Leu Asp His Met Met His Pro
              20                  25                  30        
 Asp Ser Ile Phe Asn Pro Arg Ile Cys Met Ser Val Ala Gln Leu Leu
          35                  40                  45            
 Leu Gly Val Thr Tyr Tyr Asp Pro Thr Thr Trp Thr Leu Gln Gly Ala
      50                  55                  60                
 Ser Gln Leu Pro Ala Val Pro Glu Thr Ser Leu Phe Asn Ser Ala Leu
  65                  70                  75                  80
 Asp Ser Met Gly Ser Ser Gly Ile Ala Thr Thr Ala Ile Arg Lys Lys
                  85                  90                  95    
 His Arg Lys Gly Lys Ser Lys Glu Glu Glu Glu Asp Glu Glu Asp Arg
             100                 105                 110        
 Glu Glu Lys Met Leu Tyr Ser Ser Glu Arg Cys Ser Val Lys Leu Ala
         115                 120                 125            
 Leu Arg Val Arg Glu Ala Cys Asp Leu Lys Thr Glu Asn Trp Glu Glu
     130                 135                 140                
 Thr Leu Tyr Pro Val Leu Leu Ala Gly Phe Asp Arg Ser Arg Ser Cys
 145                 150                 155                 160
 Lys Arg Ala Gly Asp Phe Arg Leu Val Val Lys Gly Leu Arg Ile His
                 165                 170                 175    
 Lys Val Arg Asn Ser Met Asn Thr Glu Lys Val Phe Lys Arg Tyr Ser
             180                 185                 190        
 Ala Ala Ser Glu Phe Asn Trp Gly Gln Leu Glu Leu Gln Asp Val
         195                 200                 205        



      <210> 1143
      <211> 101
      <212> PRT
      <213> Homo sapiens


      <400> 1143
 Met Met Ser Ser Leu Ala Leu Ala Phe Ser His Cys Val Leu Phe Gly
   1               5                  10                  15    
 Glu Leu Cys Tyr Val Ala Leu Ala Phe Asn Ser Gly Ser Val Phe Arg
              20                  25                  30        
 Asn Glu Leu Leu Pro Leu Phe Lys Glu Tyr Gly Lys Ser Lys Ile Gln
          35                  40                  45            
 Arg Cys Ala Ala Glu Gly Gly Ser Leu Pro Ile Glu Lys Tyr His Val
      50                  55                  60                
 His Gln Gly Pro Ala Val Asn Ile Ser Ala Thr Ser Ser Gly Gly Asp
  65                  70                  75                  80
 Asp Gly Leu Met Thr Thr Ser Met Asp Ser Lys Glu Glu Gly Ile Leu
                  85                  90                  95    
 Ser Ala Leu Cys Ser
             100    



      <210> 1144
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1144
 Met Gly Leu Ala Ala Asn Lys Leu Phe Met Leu Glu Ile Phe Tyr Phe
   1               5                  10                  15    
 Ala Phe Pro Phe Pro Leu Leu Ser Ala Ala Phe Ala Leu Pro Ser Gly
              20                  25                  30        
 Gly Ser Glu Ser Gly Arg Ser Thr Pro Ser Leu Ser Val Leu Ser Asp
          35                  40                  45            
 Ser Lys Pro Pro Pro Ser Thr Tyr Gln Gln Ala Pro Arg His Phe His
      50                  55                  60                
 Val Pro Asp Glu Gly Gly Ile Trp Ser Gln Gly Gly Leu Ile Trp Gly
  65                  70                  75                  80
 Leu Gly Val Cys Arg Ser Leu Gly Ala Ser Ser Cys Leu Met Ile Leu
                  85                  90                  95    
 Asn Leu Asp Thr Gly Val Lys Asp Asn Ile Tyr Arg Lys Pro Pro Ile
             100                 105                 110        
 Tyr Arg Gln His Gly Pro Ile Pro Ser Thr Pro Pro Phe Pro Gln Ala
         115                 120                 125            
 Asp Arg Gly Asn Phe Met Gly Tyr Arg Ile Gly Lys Cys Ile Leu Asn
     130                 135                 140                
 Cys Lys Val Leu Cys Thr
 145                 150



      <210> 1145
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 1145
 Met Cys Met Tyr Leu Phe Phe Leu Asp Phe Ser Ile Val Ser Val Thr
   1               5                  10                  15    
 Val Leu Leu Asp Phe Met Thr Arg Asp Arg Arg Glu Trp Ala Glu Glu
              20                  25                  30        
 Trp Arg Val Gly Leu Arg Lys Leu Val Ala Gly His Leu Cys Asp Ser
          35                  40                  45            
 Gly Ala Ser Gly Gly Trp Tyr Arg Ser Val Arg Gly Cys His Pro Val
      50                  55                  60                
 Cys Leu Ser Thr Ser Cys Val Thr Gly Cys Glu Glu Val Asn Gly Thr
  65                  70                  75                  80
 Val Glu Cys Glu Ala Val Ser
                  85        



      <210> 1146
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1146
 Met Ser Phe Leu Ile Trp Gly Ala Gln Leu Ala Glu Pro Phe Ala Pro
   1               5                  10                  15    
 Leu Ala Thr Ala Trp Thr Val Ser Lys Glu Leu Ser Pro Ser Ala Phe
              20                  25                  30        
 Cys Pro Pro Gly Cys Gln Leu Trp Leu Leu Lys Arg Leu Pro Pro Ala
          35                  40                  45            
 Ala Val Tyr Thr Ala Ser Gly Arg Gly Lys Glu Pro Gln Thr Phe Gln
      50                  55                  60                
 Ile Ala Ser Ser Arg Asn Lys Leu Phe Val Ala Asp Gly Ser Leu Leu
  65                  70                  75                  80
 Ser Leu Gly Ile Lys Met Ala Ala Glu Pro Val Glu Asp Asn Cys Ile
                  85                  90                  95    
 Asn Phe Val Ala Met Lys Phe Ile Asp Asn Thr Leu Tyr Phe Ile Ala
             100                 105                 110        
 Glu Asp Asp Gly Lys Val Glu Met Asn Leu Phe Phe Phe Ala Asn
         115                 120                 125        



      <210> 1147
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1147
 Met Ala Pro Ala Leu Trp Arg Ala Cys Asn Gly Leu Met Ala Ala Phe
   1               5                  10                  15    
 Phe Ala Leu Ala Ala Leu Val Gln Arg Cys Ser Thr Gly Leu Asp Gly
              20                  25                  30        
 Pro Leu Gly Pro Lys Pro Ala Gly Pro Ser Ser Ile Val Ala Ala Pro
          35                  40                  45            
 Ala Leu Leu Phe Lys Glu His Phe Leu Leu Cys Asn Ser Thr Ile Cys
      50                  55                  60                
 His Ala Asn Phe Thr Leu Gly Leu His Thr Val Ala Leu Gln Pro Pro
  65                  70                  75                  80
 Ile His Ile Phe Thr Met Pro Arg Pro Val Glu Tyr Gly Leu Cys Phe
                  85                  90                  95    
 Phe Thr Leu Pro Lys Ser Gln Asn Ala Val Ala Gly Ser Asp Cys Leu
             100                 105                 110        
 Ser Val Cys Ala Asp Pro Asn His Cys Gly
         115                 120        



      <210> 1148
      <211> 235
      <212> PRT
      <213> Homo sapiens


      <400> 1148
 Met Trp Phe Leu Tyr Gly Arg Phe Ile Pro Val Ser Leu Ala Phe Gly
   1               5                  10                  15    
 Glu Ile Ala Ser Glu Trp Cys Asn Arg Ala Phe Glu Ile Gln Ser Asp
              20                  25                  30        
 Ser Ser Arg His Ser Thr Lys Ala Leu Gly Cys Ser Ile Lys Gln Asp
          35                  40                  45            
 Leu Glu Glu Asp Thr Phe Thr Ser Thr Cys Asn Leu Phe Ser Val Phe
      50                  55                  60                
 Phe Leu Asn Val Ser Ala Arg Lys Arg Leu Lys Asp Asp Phe Phe Phe
  65                  70                  75                  80
 Leu Tyr Leu Ser Gly Glu Ser Leu Ser Ile Arg Ser Glu Gly Glu Leu
                  85                  90                  95    
 Phe Val Met Gly Phe Leu Val Met Gln Ala Arg Ser Lys Gly Gly Gly
             100                 105                 110        
 Met Ser Thr Met Glu Glu Gly Val Glu Val Pro Leu Asp Gly Arg Trp
         115                 120                 125            
 Phe Leu Trp Glu Lys Leu Pro Glu Glu Pro Ile Thr His Asp Arg Glu
     130                 135                 140                
 Arg Leu Ser Ser Phe Leu Phe Ile Leu Trp Ser Ser Asn Pro Asp Pro
 145                 150                 155                 160
 Ser Gly Ser Trp Tyr Thr Asp Thr Gly Ile Ser Arg Pro Ser Thr Glu
                 165                 170                 175    
 Asn Asp Arg Gly Tyr Lys Val Lys Ala Leu Gly Phe Ala Gly Lys Ala
             180                 185                 190        
 Leu Leu Ala Ser Lys Gly Phe Pro Ser Asn Asp Lys Ser Val Phe Pro
         195                 200                 205            
 Thr Ser Ser Ala Ala Pro Pro Met Pro Gly Ala Asp Glu Pro Ala Ser
     210                 215                 220                
 Gly Pro Val Ser Ser Gly Thr Val Ser Gly Thr
 225                 230                 235



      <210> 1149
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1149
 Met His Leu Leu Gln Ala Ala Leu Leu Leu Ala Val Pro Cys Leu Leu
   1               5                  10                  15    
 Cys Tyr Val Ala Val Gly Tyr Ala Phe Ser Val Leu Leu Thr Leu Leu
              20                  25                  30        
 Leu Thr Ala Pro Ala Leu Leu Pro Asp Asp Phe Glu Gly Phe Asn Ile
          35                  40                  45            
 Arg Glu Lys Thr Gly Trp Tyr Gly Lys Lys Glu Gly Met Val Thr Leu
      50                  55                  60                
 Ser Asn Pro Gln Val Ala Arg Glu Lys Glu Gln Phe Asn Asp Leu Tyr
  65                  70                  75                  80
 Phe Asn Ala Lys Gln Ala Glu Gln Lys Gly Tyr Leu Asn Thr Ala Arg
                  85                  90                  95    
 Arg Glu Ala Ser Leu Ala Phe Lys Val Thr Glu Thr Thr His Asn Lys
             100                 105                 110        
 Ser Gly Leu Ile Thr Glu Ser
         115                



      <210> 1150
      <211> 264
      <212> PRT
      <213> Homo sapiens


      <400> 1150
 Met Leu Ser Val Leu Arg Lys Cys Ser Leu Leu Pro Leu Ser Ala Ala
   1               5                  10                  15    
 Cys Leu Gln Leu Ala Pro Leu Pro Gly His Ser Gly Glu Ala Glu Ala
              20                  25                  30        
 Ala Val Ser Glu Lys Glu Ala Lys Pro Glu Lys Gly Asp Ala Ala Ile
          35                  40                  45            
 Leu Ile Thr Arg Phe Arg Ala Trp Ala Thr Val Gly Gly Arg Glu Ile
      50                  55                  60                
 Tyr Val Lys Gly Phe Val His Tyr Lys Val Arg Ala Leu Phe Pro Cys
  65                  70                  75                  80
 Glu Lys Pro Pro Arg Pro Thr Glu Met Ser Arg His His Ser Arg Phe
                  85                  90                  95    
 Glu Arg Asp Tyr Arg Val Gly Trp Asp Arg Arg Glu Trp Ser Val Asn
             100                 105                 110        
 Gly Thr His Gly Thr Thr Ser Ile Cys Ser Val Thr Ser Gly Ala Gly
         115                 120                 125            
 Gly Gly Thr Ala Ser Ser Leu Ser Val Arg Pro Gly Leu Leu Pro Leu
     130                 135                 140                
 Pro Val Val Pro Ser Arg Leu Pro Thr Pro Ala Thr Ala Pro Ala Pro
 145                 150                 155                 160
 Cys Thr Thr Gly Ser Ser Glu Ala Ile Thr Ser Leu Val Ala Ser Ser
                 165                 170                 175    
 Ala Ser Ala Val Thr Thr Lys Gly Gln Pro Leu Asp Leu Leu Ala Thr
             180                 185                 190        
 Ser Gly Arg Arg Ser Ala Gly Pro Ala Val Gly His Met Glu Asn Gly
         195                 200                 205            
 Ser Arg Trp Asn Arg Leu Leu Gly Ala Pro Ala Ala Ala Leu Gln Ala
     210                 215                 220                
 Arg Ser Cys Leu Ala Gly Arg Lys Phe Thr Ala Lys His Ser Gly Arg
 225                 230                 235                 240
 Val Arg Pro Leu Arg Lys Arg Val Val Val Asp Thr Arg Ala Val Glu
                 245                 250                 255    
 Glu Arg Phe Cys Gly Pro Phe Leu
             260                



      <210> 1151
      <211> 215
      <212> PRT
      <213> Homo sapiens


      <400> 1151
 Met Arg Arg Arg Arg Gly Gly Cys Gly Val Arg Ala Arg Ala Ala Leu
   1               5                  10                  15    
 Leu Leu Leu Pro Lys Thr Ala Val Gly Leu Ala Gln Arg Arg Val Arg
              20                  25                  30        
 Leu Pro Glu Pro Arg Pro Gln Arg Gly Val Thr Gly Ser Gly Leu Cys
          35                  40                  45            
 Ser Arg Val Pro Gly Pro Met Ser Gly Thr Ala Leu Ala Glu Ala Gly
      50                  55                  60                
 Gly Arg Arg Leu Glu Gly Gly Val Gly Ala Ser Ser Arg Arg Pro Ala
  65                  70                  75                  80
 Trp Thr Asp Ser His His Cys Pro His Ala Ala Leu Val Pro Ala Val
                  85                  90                  95    
 Leu Arg Ser Arg Met Pro Gly Gly Gly Asp Val Ala Asn Gly Pro Gly
             100                 105                 110        
 Leu Gly Gly Ala Ala Val Gln Val Pro Gln Asp Val Glu Asp Phe Arg
         115                 120                 125            
 Gly Gly Ala Gly Ala Gly Gly Ala Gln Ala His Leu Ala Gln Glu Pro
     130                 135                 140                
 Asn His Ser Leu Ser Trp Arg Ser Asn Tyr Ser Ala Ala Ala Pro Ser
 145                 150                 155                 160
 Pro Pro Gly His Ala Arg Val Gln Ala Gly Cys Cys Arg Gly Pro Asp
                 165                 170                 175    
 Pro Val Asp Asp Arg Leu Leu Thr Pro Ala Arg Pro Pro Pro Arg Pro
             180                 185                 190        
 Leu Thr Ala Ser Gln Gly Gly Pro Ser Asp Glu Gln Gly Ala Gly Gly
         195                 200                 205            
 Arg Thr Gly Gly Pro Pro Ala
     210                 215



      <210> 1152
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1152
 Met Ala Ala Ser Ala Ala Leu Ser Ala Ala Ala Ala Ala Ala Ala Leu
   1               5                  10                  15    
 Ser Gly Leu Ala Val Arg Leu Ser Arg Ser Ala Ala Ala Arg Gly Ser
              20                  25                  30        
 Tyr Gly Ala Phe Cys Lys Gly Leu Thr Arg Thr Leu Leu Thr Phe Phe
          35                  40                  45            
 Asp Leu Ala Trp Arg Leu Arg Met Asn Phe Pro Tyr Phe Tyr Ile Val
      50                  55                  60                
 Ala Ser Val Met Leu Asn Val Arg Leu Gln Ala Leu Ala Phe Val Gly
  65                  70                  75                  80
 Glu Lys Pro Lys Thr Gly Thr Lys Ser Glu Thr Glu Pro Gln Glu Glu
                  85                  90                  95    
 Ala Leu Phe Leu Ser Tyr Gln Cys Pro Leu Glu Arg Gln Gly Ile Gly
             100                 105                 110        
 Leu Glu Glu Trp Trp Asn Gly Ile Ala Lys Met Glu Asp Asp Pro Val
         115                 120                 125            
 Leu Ser Gly
     130    



      <210> 1153
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1153
 Met Ala Ala Arg Val Leu Arg Ala Arg Gly Ala Ala Trp Ala Gly Gly
   1               5                  10                  15    
 Leu Leu Gln Arg Ala Ala Pro Cys Ser Leu Leu Pro Arg Leu Arg Ala
              20                  25                  30        
 Leu Thr Gly Ala Thr Arg Gly Gln Gly Gln Gly Gln Arg Ala Pro Glu
          35                  40                  45            
 Ala Ala Gly Pro Gly Arg Arg Leu Leu Gly Pro Arg Arg Arg Leu Phe
      50                  55                  60                
 Gln Ala
  65    



      <210> 1154
      <211> 252
      <212> PRT
      <213> Homo sapiens


      <400> 1154
 Met Arg Arg Arg Pro Leu Ala Cys Leu Ala Leu Leu Ala His Leu Leu
   1               5                  10                  15    
 Pro Pro Cys His Cys Gly Lys Pro Leu Gln Gln Glu Leu His Ser Leu
              20                  25                  30        
 Gly Ala Ala Leu Ala Glu Lys Leu Asp Arg Leu Ala Thr Ala Leu Ala
          35                  40                  45            
 Gly Leu Ala Gln Glu Val Ala Thr Met Arg Thr Gln Gly Ala Ser Pro
      50                  55                  60                
 Pro Ala Ala Ser Ala Asp Ala Asp Val Pro Thr Ser Gly Val Ala Pro
  65                  70                  75                  80
 Asp Gly Ile Pro Glu Arg Pro Lys Glu Pro Ser Ser Leu Leu Gly Gly
                  85                  90                  95    
 Val Gln Arg Ala Leu Gln Glu Glu Leu Trp Gly Glu Gly Ser Gln Gly
             100                 105                 110        
 Arg Thr Gly Phe Gln Ser Phe His Gln Arg Gly Ile Val Ala Val Arg
         115                 120                 125            
 Pro Leu Leu Gly Val Leu His Thr Pro Ser Asp Cys Glu Ile Gln Asp
     130                 135                 140                
 Leu Ser Leu Val Lys Arg His Phe Lys Asp Gln Ser Leu Glu Pro Thr
 145                 150                 155                 160
 Glu Cys His Leu Ala Leu Arg Phe Ser Ala Ser Trp Thr Ser Met Ser
                 165                 170                 175    
 His Leu Gln Ser Asp Cys Arg Phe Leu Thr Asp Arg Trp His Met Leu
             180                 185                 190        
 Asp Ile Ser Val Leu Leu Thr Gly Thr Gly Thr Phe Trp Ala His Thr
         195                 200                 205            
 Gly Asp Ile Leu Gly Thr Tyr Trp Val Leu Asn Thr Arg Tyr Thr Phe
     210                 215                 220                
 Phe Gly Lys Ile Ile Arg Ser Pro Ile Ala Ser Glu Ala His Ala Asp
 225                 230                 235                 240
 Ser Ser Gln Leu Tyr Val Cys Ser Leu Ala Leu Ser
                 245                 250        



      <210> 1155
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 1155
 Met Pro Val Asn Tyr Ala Leu Cys Trp Thr Val Phe Val Leu Pro Glu
   1               5                  10                  15    
 Ala Ala Thr Arg Pro Val Leu Glu Pro His Leu Glu Thr Ser Met Thr
              20                  25                  30        
 Met Ile Ser Leu Ser Gly Ala Gly Phe Ile Lys Leu Asn Met Gln Trp
          35                  40                  45            
 Lys Leu Leu Asn Lys Val Gln Pro Gln Leu Val
      50                  55                



      <210> 1156
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1156
 Met Cys Ile Val Tyr Leu Leu Cys Asp Arg Ile Val Leu Ala Ser Glu
   1               5                  10                  15    
 Gln Gly Cys Lys Asp Val Ser Ala His Pro Arg Asn Pro Asp Tyr Glu
              20                  25                  30        
 Glu Ser Gly Glu Ser Ser Ser Ser Gly Gly Ser Glu Leu Glu Pro Ser
          35                  40                  45            
 Gly His Gln Leu Phe Cys Leu Glu Tyr Glu Ala Asp Ser Gly Glu Val
      50                  55                  60                
 Thr Ser Val Ile Val Tyr Gln Gly Asp Asp Pro Gly Lys Val Ser Glu
  65                  70                  75                  80
 Lys Val Ser Ala His Thr Pro Leu Asp Pro Pro Met Arg Glu Ala Leu
                  85                  90                  95    
 Lys Leu Arg Ile Gln Glu Glu Ile Ala Lys Arg Gln Ser Gln His
             100                 105                 110    



      <210> 1157
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 1157
 Met Arg Ile Arg Arg Thr Pro Ala Leu Ser Gly Ala Gly Phe Val Leu
   1               5                  10                  15    
 His Leu Leu Ser Arg Gln Asp Leu Leu Leu Ser Glu Asp Glu Ile Pro
              20                  25                  30        
 Ser Gly Arg Gly Glu Ser Leu Arg Asp Val Gly Gly Gly Gly Gly Ser
          35                  40                  45            
 Gly Ser Gly Tyr Ser Ala Ala Arg Gly Gly Pro Trp Pro Trp Pro Gly
      50                  55                  60                
 Val Ala Gly Leu Ser Ser Arg Arg Pro Arg Ala Ala Ser Gln Ser Gly
  65                  70                  75                  80
 Pro Thr Ser Gly Lys Glu Leu Thr Ser Asp
                  85                  90



      <210> 1158
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1158
 Met Val Val Gly Thr Ile Ser Gly Phe Leu Leu Leu Ala Asp His Thr
   1               5                  10                  15    
 Ile Leu Glu His His Leu Asn Tyr Ser Tyr Arg Gly Gly Ser Ile Arg
              20                  25                  30        
 Glu Lys Asp Asn Ser Val Ser Glu Glu Asn Thr Ser Phe Phe Leu Leu
          35                  40                  45            
 Lys Gln Glu Asp Asp Leu Asp Phe Ile Gln Arg Lys Leu Gln Ile Leu
      50                  55                  60                
 Ile Ile Leu Thr Leu Arg Ser Thr Asn Asn Phe Tyr Leu Lys Tyr Thr
  65                  70                  75                  80
 Gln Tyr Glu Thr Lys Gly Asn Met Pro Gln Lys Thr Pro Arg Asn His
                  85                  90                  95    
 Met Tyr Ile Lys Gly Met Ala Lys Glu Thr Tyr
             100                 105        



      <210> 1159
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 1159
 Met Ala His Leu Val Phe Gly Ser Phe Ala Val Ser Pro Tyr Thr Trp
   1               5                  10                  15    
 Phe Leu Leu Cys Pro Glu Ala Trp Val Thr Gln Gln Thr His Gly Asn
              20                  25                  30        
 Leu Gly Asp Ile Arg Asn Leu Leu Ile Trp Ile Lys Lys Asn Leu Leu
          35                  40                  45            
 Lys Glu Arg Pro Glu Leu Phe Ile Gln Gly Asp Ser Val Arg Pro Gly
      50                  55                  60                
 Ile Leu Val Leu Ile Asn Asp Ala Asp Trp Glu Leu Leu Gly Glu Leu
  65                  70                  75                  80
 Asp Tyr Gln Leu Gln Asp Gln Asp Ser Val Leu Phe Ile Ser Thr Leu
                  85                  90                  95    
 His Gly Gly
            



      <210> 1160
      <211> 141
      <212> PRT
      <213> Homo sapiens


      <400> 1160
 Met His Phe Glu Ser Val His Ser Leu Val Phe Tyr Ser Ile Thr Ser
   1               5                  10                  15    
 Ile Phe Leu Phe Ala Gln Tyr Leu Ile Ile Thr Leu Ser Lys Ile Thr
              20                  25                  30        
 Arg Asn Ser Ser Val Arg Lys Ala Glu Gly Lys Asn His Arg Leu Glu
          35                  40                  45            
 Val Val Trp Pro Tyr Pro Asp Glu Lys Lys Ile Gln Gln Gln Asp Ile
      50                  55                  60                
 Lys Gln Asp Phe Ile Ser Glu Val Met Ala Asp Gly Gly Ser Lys Val
  65                  70                  75                  80
 Gly His Ile Phe Ile Thr Arg Val Gln Val Thr Asn Asn Ile Val Leu
                  85                  90                  95    
 Ser Trp Ile Asn Glu Val Gln Lys Lys Ser Arg Arg His Arg Leu Glu
             100                 105                 110        
 Ile Lys Leu Glu Gly Lys Ile Asp Gln Thr Asp Val Gly Gly Val Arg
         115                 120                 125            
 Gly Gly Asp Asn Arg Met Val Ser Asn Ser Thr Leu Asp
     130                 135                 140    



      <210> 1161
      <211> 254
      <212> PRT
      <213> Homo sapiens


      <400> 1161
 Met Trp Gly Ile Gly Leu Gly Leu Val Trp Leu Ala Phe Leu Asp Arg
   1               5                  10                  15    
 Ser Gly Gln Glu Leu Lys Thr Val Thr Pro Val Ser Leu Gln Leu Phe
              20                  25                  30        
 Leu Met Gly Phe Leu Phe Ala Ser Gln Met His Leu His Arg Thr Trp
          35                  40                  45            
 Ile Leu Asn Cys Val Thr Trp Arg Gly Arg Cys Glu Arg Ala Met Leu
      50                  55                  60                
 Leu Ala Gln Pro Val Pro Val Ser Val Ser Val Val Ser Arg Pro Phe
  65                  70                  75                  80
 Cys Glu Pro Ser Val Lys Leu Phe Val Leu Gln Ser Ala Arg Lys Asn
                  85                  90                  95    
 Ile Leu Lys Val Lys Gln Trp Lys Arg Val Ile Ser Phe Glu Glu Gly
             100                 105                 110        
 Gly Ile Glu Leu Leu Gln Ala Arg Met Asp Pro Pro Leu Leu Thr Tyr
         115                 120                 125            
 Phe Gly Ala Asp Val Leu Trp Cys Arg Asp Ser Asp Thr Phe Pro Arg
     130                 135                 140                
 Glu His Gly Asn Trp Glu Ser Glu Lys Arg Tyr His Leu Val Ala Ser
 145                 150                 155                 160
 Met Leu Gln Thr Val Ile Asp Thr Glu Lys Gln Ala Thr Leu Gln Ala
                 165                 170                 175    
 Ala Glu Arg Phe Gly Asp Glu Leu Cys Ile Thr Cys Ser Ile Arg Lys
             180                 185                 190        
 Gly Gly Glu Tyr Tyr Pro Thr Gly Arg Glu Ala Val Pro Val Asn Asp
         195                 200                 205            
 Arg Lys Trp Asp Pro Asn His Glu Met Glu Ala Gly Arg Arg Arg His
     210                 215                 220                
 Phe Gln Val Cys Val Ile Glu Gly Leu Arg Lys Thr Lys Asn Lys Leu
 225                 230                 235                 240
 Ser Met Ile Asn Gln Glu Phe Asp Glu Asn Pro Ile Ala Phe
                 245                 250                



      <210> 1162
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1162
 Met Asp Ile Arg Thr Arg Trp Leu Thr Pro Val Ile Leu Ala Leu Trp
   1               5                  10                  15    
 Glu Ala Glu Gly His Leu Ala Phe Arg Asp Val Ala Ile Glu Phe Pro
              20                  25                  30        
 Gln Glu Glu Trp Lys Cys Leu Asp Pro Ala Gln Arg Thr Leu Tyr Arg
          35                  40                  45            
 Glu Val Met Val Glu Asn Tyr Arg Asn Leu Val Phe Leu Gly Ile Cys
      50                  55                  60                
 Leu Pro Asp Leu Ser Val Ile Ser Met Leu Glu Gln Arg Arg Asp Pro
  65                  70                  75                  80
 Arg Asn Leu Gln Ser Glu Val Lys Ile Ala Asn Asn Pro Gly Gly Arg
                  85                  90                  95    
 Glu Cys Ile Lys Gly Val Asn Ala Ala Pro Leu Cys Gly Phe Gly Val
             100                 105                 110        
 Arg His Pro His Arg Glu Lys Arg Ile Phe Arg Gly Val Glu Leu Gly
         115                 120                 125            
 Arg Gln Glu Tyr Pro Val Ser
     130                 135



      <210> 1163
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1163
 Met Ile Gly Lys Ile Trp Leu Thr Ile Leu Phe Ile Phe Arg Met Leu
   1               5                  10                  15    
 Val Leu Gly Val Ala Ala Glu Asp Val Trp Asn Asp Glu Gln Ser Gly
              20                  25                  30        
 Phe Ile Cys Asn Thr Glu Gln Pro Gly Cys Arg Asn Val Cys Tyr Asp
          35                  40                  45            
 Gln Ala Phe Pro Ile Ser Leu Ile Arg Tyr Trp Val Leu Gln Val Ile
      50                  55                  60                
 Phe Val Ser Ser Pro Ser Leu Val Tyr Met Gly His Ala Leu Tyr Arg
  65                  70                  75                  80
 Leu Arg Val Leu Glu Glu Glu Arg Gln Arg Met Lys Ala Gln Leu Arg
                  85                  90                  95    
 Val Glu Leu Glu Glu Ala Ala Asp Ser Lys Arg Glu Gln Phe Arg Arg
             100                 105                 110        
 Tyr Leu Glu Lys Ser Gly Val Leu Asp Thr Leu Thr Lys Glu Gln Leu
         115                 120                 125            
 Glu Lys
     130



      <210> 1164
      <211> 210
      <212> PRT
      <213> Homo sapiens


      <400> 1164
 Met Gly Trp Gly Trp Gly His Leu Cys Leu Arg Ser Ala Val Ala Cys
   1               5                  10                  15    
 Leu Ala Trp Glu Ala Trp Arg Ser Ser Arg Asp Pro Gly His Cys Ile
              20                  25                  30        
 Thr Gln Val Ala Leu Ser Asp Gln Gly Ser Pro Gly Leu Arg Ser Val
          35                  40                  45            
 Leu Thr Leu Gly Met Met Ser Ser Ser His Gly Gly Lys Ser Ser Asp
      50                  55                  60                
 Thr Ala Lys Ala Glu Asp His Leu Gly Thr Thr Leu Ser His Leu Asp
  65                  70                  75                  80
 Arg Thr Gly His Arg Glu Leu Ser Gly Leu Glu Glu Glu Thr Ser Gln
                  85                  90                  95    
 Gly Cys Gly Gly Glu Glu Gly Gln Pro Gln Ser His Cys Lys Ser Ser
             100                 105                 110        
 Leu Arg Pro Gly Asp Ser Glu Ala Glu Thr Met Ser Pro Ala Arg Gly
         115                 120                 125            
 Ser Gly Ser Asp Thr Thr Gly Ala Ser Phe Gln Glu Glu Arg Arg Ile
     130                 135                 140                
 Pro Val Lys Gln Gln Leu His Val Arg Gly Leu Gly Arg Thr Gln Asp
 145                 150                 155                 160
 Cys Leu Thr Gly Trp Gly Arg Cys Gly Arg Lys Leu Ser Gly Arg Ala
                 165                 170                 175    
 Phe Ser Gln Gly Glu Asp Phe Leu Gly Pro Phe Gln Leu Trp Asp Ser
             180                 185                 190        
 Gly Ile Gly Val Ile Val Thr Gln Gln Leu Glu Met Thr Gln Ala Leu
         195                 200                 205            
 Ser Asp
     210



      <210> 1165
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 1165
 Met Leu Met Pro Gly Leu Ser Ala Cys Val Arg Asp Cys Val Ala Phe
   1               5                  10                  15    
 Leu Gln Ala Val Val Leu Gly Asp Pro Ser Pro Ala Ala Gln Cys Gln
              20                  25                  30        
 Asp Thr Trp Thr Leu Ala Ala Ser Ala Asp Gly Thr Cys Lys Ala Val
          35                  40                  45            
 Gly Thr Glu Asp Gly Ser Val Tyr Phe Ile Ser Val Tyr Asp Lys Glu
      50                  55                  60                
 Ser Pro Gln Val Val His Lys Ala Phe Leu Ser Glu Ser Ser Val Gln
  65                  70                  75                  80
 His Val Val Tyr Asp Gln Gln Gly Ile Phe Leu Leu Val Gly Thr Ala
                  85                  90                  95    
 Glu Gly Lys Val Phe Ile Ile Asn Ala Asn Ser Ser Ser Ser Phe Gln
             100                 105                 110        
 Ile Ile Gly Phe Thr Glu Val Ala Lys Asp Ile Leu Gln Ile Ser Thr
         115                 120                 125            
 Val Ser Leu Leu Glu Thr Asp Ile Val Glu Val Met Val Leu Ser Ser
     130                 135                 140                
 Leu Pro Glu Ala Gly Arg Ser Arg Leu Glu Met Phe Thr Leu Pro Thr
 145                 150                 155                 160
 Leu Leu Pro Gln Gly Arg Leu Lys Asp Glu Ile Ile Leu Lys Tyr Leu
                 165                 170                 175    
 Tyr Glu Leu Glu His Ala Leu Ser Ser Ala Val Leu Gly Phe Gln Ser
             180                 185                 190        
 Asn Gln Ile Tyr Gly Phe Cys Ser Gln Val Pro Tyr Ile Cys Ser Tyr
         195                 200                 205            
 Leu Leu Pro Glu Glu Glu His Thr Gly Ile Tyr Ile Leu Lys Pro Tyr
     210                 215                 220                
 Lys Lys Val Gln Ser Arg Gln Tyr Gly Pro Gly Leu Leu Tyr Leu Ser
 225                 230                 235                 240
 Ser His Gly Leu Trp Leu Ile Thr Ile Ala Lys Cys Gly Ile Leu Cys
                 245                 250                 255    
 Ile Arg Asp Val Tyr Thr Leu Gly His Gly Ile Gln Ser Met Arg Ile
             260                 265                 270        
 Ser Met Asp Gly Gln Asn Ile Leu Val Asn Gly Arg Asp Asp Gly Thr
         275                 280                 285            
 Leu Val Tyr Leu Lys Trp Lys Tyr Val Gln Tyr Ser Thr Cys Leu Ser
     290                 295                 300                
 Phe Ser Thr Met Tyr Gln Lys Gln Lys Ala Ser Thr Asp Leu Ser Gln
 305                 310                 315                 320
 Asp Glu Leu Val Leu Thr Asp Val Lys Lys Glu Ile Pro Trp Ile Gln
                 325                 330                 335    
 Gln Lys Ser Gln Glu Val Phe Val Lys His Gly Val Gly Leu Lys
             340                 345                 350    



      <210> 1166
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1166
 Met Pro Cys Glu Ser Leu Lys Leu Lys Ala Phe Phe Val Arg Val Leu
   1               5                  10                  15    
 Val Leu Thr Ala Lys Leu Asn Ile Thr Gln Leu Asp Gly Gln Thr Ala
              20                  25                  30        
 Glu Leu Ala Pro Thr Gly Arg Arg Ser Glu Ser Leu Leu Leu Glu Asp
          35                  40                  45            
 Lys Gln Arg Glu His Ser Glu Gly Lys Asn Glu Asn Asn Thr Glu Arg
      50                  55                  60                
 Pro Arg Lys Asn Gln Gly Asn Thr Glu Tyr Ser Asn His Phe
  65                  70                  75            



      <210> 1167
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1167
 Met Gly Arg Asn Leu Lys Gln His Gln Ala Gln Arg Gln Gln Val Pro
   1               5                  10                  15    
 Val Thr Ala Leu Met Leu Trp Ala Leu Ile Gly Ala Ala Leu Ala Pro
              20                  25                  30        
 Leu His Thr Gln Glu Pro Lys Lys Gly Asp Glu Glu Lys Met Ser Pro
          35                  40                  45            
 Ala Ile Ser Pro Pro Leu Pro Ser Ala Leu Ile Ser Pro Gly Gln Asn
      50                  55                  60                
 Asn Lys Glu Glu Thr Glu Val Leu Pro Glu Pro Pro Pro Pro Ile Asp
  65                  70                  75                  80
 Arg Lys Lys Asp Arg Gly Tyr Ala Thr Thr Ile Ser Pro Cys Leu Lys
                  85                  90                  95    
 Gln Ala Glu Leu Lys Gly
             100        



      <210> 1168
      <211> 368
      <212> PRT
      <213> Homo sapiens


      <400> 1168
 Met Leu Tyr Trp Leu Met Pro Lys Gly Lys Leu Leu Trp Ile Ala Ser
   1               5                  10                  15    
 Phe Leu Thr Arg Leu Gln Gly Ile Gln His Thr Leu Pro Arg Val Glu
              20                  25                  30        
 Glu Lys Ser Ile Gln Ser Val Lys Asp Asp Asn Ile Tyr His Pro His
          35                  40                  45            
 Pro Arg Pro Arg Ile Ala Val Val Gly Ser Ser Ser Thr Val Ile Ser
      50                  55                  60                
 Tyr Ser Pro Gly Glu Tyr Ala Phe Thr Asn Gly Thr Ser Arg Cys Pro
  65                  70                  75                  80
 Ser Leu Ser Leu Ala Ala Gly Pro Arg Leu Ile Thr Asn Gly Pro Trp
                  85                  90                  95    
 Glu Ala His Glu Val Gln Arg Glu Ser Thr Ile Ala Leu Met Lys Leu
             100                 105                 110        
 Leu Gln Val Leu Glu Gln Lys Val Arg Leu Arg Glu Gly His Ser Leu
         115                 120                 125            
 Gly Thr Val Lys Met Ser Lys Asn Ile Asn Pro Met Gly His Val Ser
     130                 135                 140                
 Asn Pro Pro Thr Ser Tyr Pro Asp Glu Leu Ile Thr Lys Gln Val Cys
 145                 150                 155                 160
 Pro Gly Ser His Pro Lys Arg Pro Gly Glu Val Lys His Asn Glu Glu
                 165                 170                 175    
 Val Pro Thr Ser Gln Asp Arg Asp Thr Cys Thr Thr Gln Glu Thr Gln
             180                 185                 190        
 Tyr Ser Val Arg Lys Ile Ile Ser Ala Glu Asp Asp Phe Thr Val Lys
         195                 200                 205            
 Asn Tyr Asn His Ile Arg Asn Lys Phe Thr Ile Pro Ser Arg Lys Gly
     210                 215                 220                
 Gln Gln Ala His Arg Ala Trp Leu Asn Lys Ala Ile Pro Gln Pro Met
 225                 230                 235                 240
 Pro Thr Ser Ala Thr Ser Leu Leu Ala Ala Leu Val Arg Ala Ala Lys
                 245                 250                 255    
 His Arg Asn Gln Gln Pro Gln Asp Leu Ala Gln Ser Ser Ser His His
             260                 265                 270        
 Ile Tyr Leu Phe Ile Thr Ile Thr Phe Gly Ser Leu Arg Asp Ser Glu
         275                 280                 285            
 Leu Lys Ser Lys Arg Gly Pro Asp Pro Gln Leu Ser Leu Glu Leu Glu
     290                 295                 300                
 Met Val Ala Lys Ala Lys Ala Val Lys Pro Glu Asn Ser Arg Arg Trp
 305                 310                 315                 320
 Phe Ser Gly Asn Gln Leu Gly Ser Ile Ile Asn Ser Pro Lys Lys Gly
                 325                 330                 335    
 Ser Ala Val Leu Glu Gly Thr Phe Gln Glu Lys Gln Lys Trp Asp Ala
             340                 345                 350        
 Arg Leu Thr Lys Gly Asp Cys Leu Ala Thr Asn Val Leu Asn Arg Val
         355                 360                 365            





      <210> 1169
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1169
 Met Ser Thr Val Phe Thr Ala Val Pro Ser Leu Trp Leu Gly Val Ser
   1               5                  10                  15    
 Gly Ala Asp Asp Arg Pro Pro Gln Pro Asp Ser Val Pro Thr Val Ala
              20                  25                  30        
 Val Cys Gly Gly Ser Asp Asp Arg Leu Pro Gln Pro Asp Ser Val Pro
          35                  40                  45            
 Thr Val Ala Val Cys Arg Gly Ser Asn Asp Arg Pro Pro Gln Pro Asp
      50                  55                  60                
 Ser Val Leu Thr Val Ser Val Cys Val Gly Ala Asp Asp Arg Pro Pro
  65                  70                  75                  80
 Gln Pro Asp Ser Gly Phe Ser Trp Ala Thr Ser Gln Cys His Lys Glu
                  85                  90                  95    
 Asn His Ser Gly Ala Leu Glu Arg Gly Lys Ala
             100                 105        



      <210> 1170
      <211> 314
      <212> PRT
      <213> Homo sapiens


      <400> 1170
 Met Ala Ala Cys Val Met Leu Leu Pro Gly Leu Ser Ser Leu Ile Cys
   1               5                  10                  15    
 Leu Gln Glu Pro Asp Thr Thr Ser Pro Thr Pro Cys Ile Arg Gly Pro
              20                  25                  30        
 Glu Ala Leu Cys Gly Glu Gly Pro Phe Trp Pro Leu Ser Ser Val Ala
          35                  40                  45            
 Asp Gly Tyr Val Val Leu Leu His Met Thr Arg Thr Ile Ser Lys Phe
      50                  55                  60                
 Leu Asn Thr Phe Gln Glu Phe Leu Thr Ile Lys Ala Leu Gly Ser Gly
  65                  70                  75                  80
 Ser Asp Asn Arg Val Gly Ser Phe Leu Arg Gln Gln Lys Cys Gly Trp
                  85                  90                  95    
 Val Pro Gln Ala Ala Asp Glu Thr Arg Arg Ile Tyr Cys Arg Val Thr
             100                 105                 110        
 Tyr Leu Asn Ser Glu Thr Val Ser Gly Arg Cys Arg Asn Glu Arg Gln
         115                 120                 125            
 Ile Ser Asn Thr Leu Ser Gly Val Leu Pro Ile Pro His Ser Leu Ile
     130                 135                 140                
 Asn Ala Gly Phe Thr Val Glu Lys Pro Trp Phe Gly Val Thr Thr Glu
 145                 150                 155                 160
 Glu Asn Phe Gln Lys Asp Val Arg Thr His Glu Gln Glu Arg Trp Asn
                 165                 170                 175    
 Leu Arg Thr Ala Glu Lys His Lys Glu Glu Pro Ala Met Glu Glu Met
             180                 185                 190        
 Asn Pro Glu Arg Arg Ser Ser Ser Ser Leu Ala Val Phe His Glu Leu
         195                 200                 205            
 Gly Ala Tyr Arg His Leu Ser Ala Ile Thr Asn Phe Met Leu Thr Tyr
     210                 215                 220                
 Gln Pro Gln His Cys Leu Asn Ile Asn Leu Thr Pro Ala Phe Ile Gln
 225                 230                 235                 240
 Ile Arg Gly Trp Ile Val Glu Ile Glu Gly Glu Glu Leu Gln Ser Tyr
                 245                 250                 255    
 Ser Lys Gln Lys Ala Ser Gln Asn Ile Val Gly Ile Tyr Asn Val Met
             260                 265                 270        
 His Asn Gln Ser Val Gln Val Ser Glu Asn Leu Arg Leu Thr Cys Ala
         275                 280                 285            
 Ala Gly Cys Ala Tyr Phe Arg His Leu Lys His Gln Arg Pro Lys Asp
     290                 295                 300                
 Gly Thr Tyr Phe Ser Asp Lys Ile Lys Thr
 305                 310                



      <210> 1171
      <211> 182
      <212> PRT
      <213> Homo sapiens


      <400> 1171
 Met Ala Ala Val Ala Leu Ala Ser Gly Thr Arg Leu Gly Leu Val Leu
   1               5                  10                  15    
 Glu Leu Leu Pro Gly Gln Pro Ala Leu Pro Arg Ala Arg Arg Glu Ser
              20                  25                  30        
 Val Thr Phe Glu Asp Val Ala Val Tyr Phe Ser Glu Asn Glu Trp Ile
          35                  40                  45            
 Gly Leu Gly Pro Ala Gln Arg Ala Leu Tyr Arg Asp Val Met Leu Glu
      50                  55                  60                
 Asn Tyr Gly Ala Val Ala Ser Leu Ala Ala Phe Pro Phe Pro Lys Pro
  65                  70                  75                  80
 Ala Leu Ile Ser Gln Leu Glu Arg Gly Glu Thr Pro Trp Cys Ser Val
                  85                  90                  95    
 Pro Arg Gly Ala Leu Asp Gly Glu Ala Pro Arg Gly Ile Ser Ser Val
             100                 105                 110        
 Glu Lys Ser Trp Ala Pro Ser Leu Phe Pro Gly Thr Arg Tyr Asp Ile
         115                 120                 125            
 Glu Phe His Asp Tyr Ala Cys Thr Leu Gly Tyr Asn Pro Pro Gly Gly
     130                 135                 140                
 Arg Thr Ser Ile Val Ser Phe Phe Val Leu Pro Thr Glu Pro Val Gly
 145                 150                 155                 160
 Asp Leu His Thr Gly Ala Leu Gln Ser Val Leu Ile Glu Leu Leu Lys
                 165                 170                 175    
 Ala Ala Ser Leu Gln Ser
             180        



      <210> 1172
      <211> 128
      <212> PRT
      <213> Homo sapiens


      <400> 1172
 Met Ala Cys Arg Val Leu Gln Gly Leu Pro Phe Ala Cys Leu Ser Ser
   1               5                  10                  15    
 Pro Ile Cys Ser His Ser Ala Leu Thr Leu Asp His Ser Leu Leu Cys
              20                  25                  30        
 Leu Asn Phe Phe Phe Asn Pro Tyr Ala Leu Leu Pro Asn Phe Tyr Leu
          35                  40                  45            
 Phe Gly Lys Phe Gln Leu Arg Ile Pro Ser Ser Gly Lys Pro Phe Leu
      50                  55                  60                
 Thr Ser Glu Asp Gln Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val
  65                  70                  75                  80
 Val Gly Asn Gly Thr Tyr Gly Gln Val Tyr Lys Val Arg Arg Met Val
                  85                  90                  95    
 Trp Lys Tyr Asp Leu His Ile Cys Arg Ala Val Leu Gly Gly Val Glu
             100                 105                 110        
 Gly Ser Arg Phe Leu Val Cys Arg Ser Glu Gly Gly Tyr Gly Arg Cys
         115                 120                 125            





      <210> 1173
      <211> 143
      <212> PRT
      <213> Homo sapiens


      <400> 1173
 Met Leu Leu Pro Leu Phe Leu Leu Ile His Thr Gly Ile Gly Pro Ser
   1               5                  10                  15    
 Tyr Ser Ala Ser Asp Arg Ala Glu Pro Arg Pro Ser Pro Gly Gly Arg
              20                  25                  30        
 Leu Thr Ala Arg Ile Trp Ile Lys Gly Val Lys Glu Asp Gly Gly Thr
          35                  40                  45            
 Met Gln Gly Ala Val Asp Trp Gly Glu Gly Val Glu Asp Ala Gln Asp
      50                  55                  60                
 Ala Ser Leu Arg Ala Ile Arg Leu Gln Thr Asn Gly Ile Arg His Gly
  65                  70                  75                  80
 Ile Pro Trp Val Val Arg Pro Ser Leu Glu Arg Gln Pro Leu Asp Arg
                  85                  90                  95    
 Gly Trp Val Ser Ala Ile Leu Ala Cys Pro Pro Pro Arg Cys Pro Gly
             100                 105                 110        
 Leu Arg Pro Glu Arg Arg Pro Arg Met Arg Ser Val Arg Arg Gly Ser
         115                 120                 125            
 Thr Thr Ser Val Ala Gly Gln Ser Gln Val Glu Gln Gly Gly Cys
     130                 135                 140            



      <210> 1174
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1174
 Met Ser Ser Glu Val Val Ala Leu Leu Cys Trp Ala Cys Ser Thr Cys
   1               5                  10                  15    
 Asp Arg Leu Gly Gln Gln Arg Gly Ala Gly Glu Gly Gln Gly Ala Gly
              20                  25                  30        
 Leu Pro Gln Glu Asp Ala Gly Ala Ala Pro Met Arg Leu Gln Gln His
          35                  40                  45            
 Ala Thr Ala Ile Asp Lys Asn Pro Ala Ser Ile Ser Ser Arg Ala Thr
      50                  55                  60                
 Ala Gln Leu Arg Gly Phe Pro Val Cys His Thr Ala Ala Ala Thr Arg
  65                  70                  75                  80
 Asp Pro Ser Val Arg His Trp Gln Gln Leu Ser Ala Pro Gln Gln His
                  85                  90                  95    
 Ser Gly His Ala Leu Ala His Thr Leu Arg Thr Ile Ser Ala Val Ala
             100                 105                 110        
 Thr Asn Ala Arg Gly
         115        



      <210> 1175
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 1175
 Met Gln Ala Gly Leu Ala Arg Ala Met Val Leu Ala Ala Gly Trp Ser
   1               5                  10                  15    
 Arg Val Ala Ser Ala Gly Ala Ala Gly Asp Thr Ser Pro Val Pro Arg
              20                  25                  30        
 Ala Leu Ser Asp Leu Arg Ile Thr Gln Lys Cys Gly Leu Leu Val Pro
          35                  40                  45            
 Lys Ala Val Ser Trp Lys Ser Leu Phe Leu Phe Pro Ile Thr Val Glu
      50                  55                  60                
 Leu
  65



      <210> 1176
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1176
 Met Ala Ala Ala Ala Leu Pro Pro Arg Pro Leu Leu Leu Leu Pro Leu
   1               5                  10                  15    
 Val Leu Leu Leu Ser Gly Arg Pro Thr Arg Ala Asp Ser Lys Gly Lys
              20                  25                  30        
 Leu Leu Ala Thr Val Thr Gln Arg Leu Pro Gly Leu Gln Gln Ala Leu
          35                  40                  45            
 Gly His Gly Phe His Gly Pro Leu Gly Thr Gly Gly Leu Leu Tyr Pro
      50                  55                  60                
 Met Asn Ala Ala Ala Leu Ala Thr Arg Leu Ala Ser Asp Val Leu Ala
  65                  70                  75                  80
 Arg Asp Arg Val His Pro Leu Glu Asp
                  85                



      <210> 1177
      <211> 164
      <212> PRT
      <213> Homo sapiens


      <400> 1177
 Met Ala Ala Val Val Ala Ala Thr Arg Trp Trp Gln Leu Leu Leu Gly
   1               5                  10                  15    
 Ala Gln Arg Arg Val Asp Gly Gly Leu Gly Ala Arg Ser Ser Pro Thr
              20                  25                  30        
 Ser Cys Ser Cys Ser Trp Thr Thr Asn His Ser Arg His Leu Gly Pro
          35                  40                  45            
 Pro Gly Pro Pro Ala Gly Leu Gln Ser Tyr Leu Thr Ala Val Ser Val
      50                  55                  60                
 Leu Trp Arg Met Leu Ser Glu Ala Ala Thr Pro Gly Gly Leu His Leu
  65                  70                  75                  80
 Ser Arg Arg Ala His Val Val Cys Glu Asp Trp Asp Asp Thr Glu Tyr
                  85                  90                  95    
 Gln Thr Val Leu Gly Arg Arg Cys Arg Ser Ala Pro Val Cys Trp Leu
             100                 105                 110        
 Arg Pro Ala Glu Thr Leu Thr Gly Ala Phe Arg Pro Thr Cys Ala Asp
         115                 120                 125            
 Gln Trp Gly Pro Arg Pro His Pro Arg Ala Gly Gln Ser Trp Leu Ser
     130                 135                 140                
 Glu Leu Glu Gly Ala Gly Ser Val Lys Tyr Thr Asp Leu Glu Asp Leu
 145                 150                 155                 160
 Val Lys Glu Lys
                



      <210> 1178
      <211> 375
      <212> PRT
      <213> Homo sapiens


      <400> 1178
 Met Leu Leu Pro Met Leu Arg Thr Ser Cys Ser Thr Phe Leu Thr Ala
   1               5                  10                  15    
 Leu Leu Gly Gly Ser Gln Thr Met Gly Trp Thr Thr Ala Ala Ser Leu
              20                  25                  30        
 Asp Met Gly Ala Pro Gly Gln Cys Arg Ala Ser Arg Val Gln Gly Gln
          35                  40                  45            
 Gly Thr Val Ser Ser Pro Lys Glu Gly Gln Asp Phe Asn Ala Phe Cys
      50                  55                  60                
 Cys Cys Leu Leu Ala Gly Ala Glu Glu Ala Ser Gly Pro His Arg Glu
  65                  70                  75                  80
 Thr Gln Ala Ser Leu Gln Pro Ser Ser Glu Pro Asn Glu Val Val Cys
                  85                  90                  95    
 Ser Ala Gln Gln Gln Leu Leu Gln Leu Leu Thr Pro Arg Ile His Pro
             100                 105                 110        
 Lys Arg His Arg Ala Leu Ser Arg Gly Asn Gln Pro Ser Val Phe Lys
         115                 120                 125            
 Thr His Pro Val Leu Gln Ala Ala Pro Thr Ser Ser Lys Ala Gln Ala
     130                 135                 140                
 Ser Val Ala Gly Glu Ala Glu Leu Thr Thr Ala Arg Asn Ser Pro Ser
 145                 150                 155                 160
 Arg Gly Ser Lys Pro Pro Glu Pro Thr Leu Phe Cys Val Phe Ser Val
                 165                 170                 175    
 Gln Leu Pro Ala Pro Arg Pro Val Ile Gly His Leu Pro Leu Ala Ser
             180                 185                 190        
 Ile Thr His Gln Pro Pro Ala Val Met Ala Ala Ala Leu Gly Met Leu
         195                 200                 205            
 Asn Pro Asp Arg Pro Ser His Ala Glu Asp Ala Gln Arg His His Lys
     210                 215                 220                
 Gln Ser Pro Glu Leu Trp Glu Tyr Thr Ala Ser Phe Pro Glu Phe Arg
 225                 230                 235                 240
 Leu Glu Pro Ser Lys Val Tyr Pro Ser Ala Thr Cys Ser Leu Thr Leu
                 245                 250                 255    
 Gln Gly Trp Pro Gln Thr Thr Thr Leu Cys Thr Leu Gly Arg Arg Gln
             260                 265                 270        
 Gln Gln Ser Pro Ser Gln His Asn His Met Gln Ile Glu Glu Ala Thr
         275                 280                 285            
 Ile Thr Asp Leu Gly Ser Pro Ala Gln Arg Glu Ala Ala Asp Val Ser
     290                 295                 300                
 Ala Ser Arg Thr Ser Thr Glu Gly Thr Gly Arg Leu Val Cys Ile Pro
 305                 310                 315                 320
 Asp Gln Gln His Gln Lys Gly Ser Pro Glu Arg Trp Pro Gly Asn Ala
                 325                 330                 335    
 Met Pro Arg Val Arg Arg Met His Arg Ala Ser His Pro Glu Trp Cys
             340                 345                 350        
 Gly Leu Ala Ala Pro Lys Ser Arg Gln Met His Asp Gly Arg Arg Thr
         355                 360                 365            
 Ala Ala Glu Arg Ala Thr Gln
     370                 375



      <210> 1179
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1179
 Met Ala Ser Ser Ala Leu Thr Leu Gly Gln Leu Gly Trp Leu Gly His
   1               5                  10                  15    
 Ala Ala Trp Ala Ala Pro Arg Ala Gly Ala Cys Ser Leu Leu Thr Ala
              20                  25                  30        
 Pro Trp Leu Cys Gly Ala Leu Cys Thr Glu Arg Leu Tyr Pro Leu Ser
          35                  40                  45            
 Trp Gln Ala Glu Leu Arg Pro Arg Leu Ala Cys Arg Glu Arg Arg Arg
      50                  55                  60                
 Pro Gly Arg Ala Arg Ser Arg Glu Trp Thr Leu Gly Lys Gly Trp Gln
  65                  70                  75                  80
 Leu Gly Pro Ser Glu Pro Gly Glu Asp Leu Leu Ser Glu Gly Phe Asn
                  85                  90                  95    
 Pro Leu Ala Lys Pro Ser Ser Ala Lys Ser Leu Leu Asn Lys Lys Ser
             100                 105                 110        
 Asp Gly Gly Val Lys Gly Ile Phe Leu Ser Leu Leu Val Cys Phe Lys
         115                 120                 125            
 Pro Asp Ala Phe Val Leu Arg Thr Glu Gly Ser Ala Gly Leu Arg Gly
     130                 135                 140                
 Lys
 145



      <210> 1180
      <211> 185
      <212> PRT
      <213> Homo sapiens


      <400> 1180
 Met Glu Pro Arg Ala Leu Val Thr Ala Leu Ser Leu Gly Leu Ser Leu
   1               5                  10                  15    
 Cys Ser Leu Gly Leu Leu Val Thr Ala Ile Phe Thr Asp His Trp Tyr
              20                  25                  30        
 Glu Thr Asp Pro Arg Arg His Lys Glu Ser Cys Glu Arg Ser Arg Ala
          35                  40                  45            
 Gly Ala Asp Pro Pro Asp Gln Lys Asn Arg Leu Met Pro Leu Ser His
      50                  55                  60                
 Leu Pro Leu Arg Asp Ser Pro Pro Leu Gly Arg Arg Leu Leu Pro Gly
  65                  70                  75                  80
 Gly Pro Gly Arg Ala Asp Pro Glu Ser Trp Arg Ser Leu Leu Gly Leu
                  85                  90                  95    
 Gly Gly Leu Asp Ala Glu Cys Gly Arg Pro Leu Phe Ala Thr Tyr Ser
             100                 105                 110        
 Gly Leu Trp Arg Lys Cys Tyr Phe Leu Gly Ile Asp Arg Asp Ile Asp
         115                 120                 125            
 Thr Leu Ile Leu Lys Asp Leu Gly Arg Asp Leu Glu Met Pro Val Glu
     130                 135                 140                
 Leu Leu Glu Glu Leu Asp Thr Trp Glu Ile Val Ile Lys Ala Ala Lys
 145                 150                 155                 160
 Asp Arg Gly Pro Cys Pro Asp Cys His Phe Leu Leu Leu Pro Leu Met
                 165                 170                 175    
 Ala Leu Gly Phe Gly Phe Phe Leu Pro
             180                 185



      <210> 1181
      <211> 243
      <212> PRT
      <213> Homo sapiens


      <400> 1181
 Met Asn Val Thr Arg Arg Trp Ala Arg Ser Cys Phe Gly Cys Ile Thr
   1               5                  10                  15    
 Leu Leu Val Pro Glu Val Trp Glu Leu Ala Phe Ser Glu Ala Ile Gln
              20                  25                  30        
 Ser Arg Ala Asn Ser His Cys Gln Tyr Tyr Met Gly Leu Lys Gln Ile
          35                  40                  45            
 Pro Pro Asn Asp Leu Ile Asn Ser Leu Asn Glu Lys Arg Gln Lys Glu
      50                  55                  60                
 Glu Val Phe Cys Asp Arg Arg Tyr Ala Asp Gly Leu Arg Arg Pro Asp
  65                  70                  75                  80
 Pro Gln Gly Lys Gly Gln Gln Leu Gly Arg Arg Ala Val Pro Leu Tyr
                  85                  90                  95    
 Arg Phe Pro Arg Lys Arg Ala Arg Gly Asn Gly His Gly Trp Trp Val
             100                 105                 110        
 Cys Pro Gln Gln Arg Leu Ala Val Ala Ile Arg Ser Pro Asp Val Leu
         115                 120                 125            
 Gly Ile Ala Val Ala Pro Gly Lys Trp Ala Leu Asp Ala Gly Val Gly
     130                 135                 140                
 Lys Pro Ser Leu Gly Ala Arg Val Ala Gly Ala Glu Gly Arg Arg Gly
 145                 150                 155                 160
 Gly Lys Leu Ala Gly Glu Glu Trp Glu Gly Asp Gln Gly Gln Gln Gln
                 165                 170                 175    
 Gly Leu Leu Arg Gly Ala Val Glu Glu Leu Ser Pro Gly Arg Gly Lys
             180                 185                 190        
 Asp Gln Ala Thr Ser Pro Lys Glu Pro Asp Phe Ser Pro Ser Ala Gly
         195                 200                 205            
 Val Pro Glu Pro Gly Tyr Val Gly Thr Ala Pro Cys Lys Val Ser Ile
     210                 215                 220                
 Met Gln Val Arg Glu Asp Thr Arg Ile Ser Lys Arg Thr Asp Leu Asn
 225                 230                 235                 240
 Ala Glu Leu
            



      <210> 1182
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 1182
 Met Lys Thr Lys Tyr Ser Glu Val Ala Phe Ala Met Ala Thr Gly Ser
   1               5                  10                  15    
 Ser Trp Gly Leu Val Pro Val Leu Leu Gln Gly Leu Arg Ser Ile Ser
              20                  25                  30        
 His Trp Leu Gly Leu Ser Leu Phe Leu Pro Leu His Leu Glu Leu Leu
          35                  40                  45            
 Ser Phe Leu Trp Phe Gly Ala Asp Trp Val Gly Ser Gly Leu Arg Val
      50                  55                  60                
 Ile Ala Leu Gly Ile Pro Ser Glu Gly Ala Asn Leu Arg Phe Leu Arg
  65                  70                  75                  80
 Gly Pro Asp Ser Gln Gly Arg Ala Leu Ser Pro Glu Ala Ser Ala Ser
                  85                  90                  95    
 Thr Cys Met Val His Arg Lys Gly Ser Trp Ala Gln Asn Leu Glu Asn
             100                 105                 110        
 Arg Leu Leu Leu Thr Ile Gln Gln Arg Gln Pro Val Leu His Ser Pro
         115                 120                 125            
 Ser Leu Cys Cys Asp Pro Ser Leu Leu Leu Leu Ala Val Pro Asn Ala
     130                 135                 140                
 Lys Gln Ala Phe His Ser Gly Gln Pro Gly Arg Gln Gly Leu Arg Val
 145                 150                 155                 160
 Glu Ala Pro Gly Ser Leu Ser Ser Leu Cys Leu Ser Leu Ala Val Ala
                 165                 170                 175    
 Leu Ala Ile Asn Trp Asn Tyr Val Ile Ile Tyr Lys Thr Gly Ala Ile
             180                 185                 190        
 Thr Gly Leu Trp Gln Asp Trp Pro Thr Arg Val Thr Ala Cys Phe His
         195                 200                 205            
 Gln Pro Lys Trp Thr Gly Arg Glu Cys Gly Pro Ser Ala Arg Ile Trp
     210                 215                 220                
 Glu Arg Arg Trp Gly Met Glu Ser His Ala Glu Val Glu Gly Lys Met
 225                 230                 235                 240
 Asp Leu Asp Ala Ile Ser Glu
                 245        



      <210> 1183
      <211> 165
      <212> PRT
      <213> Homo sapiens


      <400> 1183
 Met Pro His Cys Ser Arg Val Ser Leu Leu Ser Leu Leu Ser Leu Leu
   1               5                  10                  15    
 Pro Gly Thr Pro Thr Gly Gln Leu Glu Ala Ser Leu Gln Gly Ala Gly
              20                  25                  30        
 Ala Tyr Pro Pro Leu Glu Gly Arg Lys Lys Thr Asn Ser Ser Leu His
          35                  40                  45            
 Ala Phe Glu Ala Gly Leu Ser Thr Lys Asp Leu Leu Asn Gln Phe Thr
      50                  55                  60                
 Thr Ser Asn Arg Met Gln Ala Val Leu Arg Asn Gly Ser Gln Arg Ser
  65                  70                  75                  80
 Thr Glu Lys Gly Cys Leu Lys Ala Glu Ala Gly Asp Val Ser Leu Leu
                  85                  90                  95    
 Lys Met Glu Ile Gly Pro Ser Ser Phe Ser Val Glu Ser Glu Val Pro
             100                 105                 110        
 Arg Pro Ser Gln Cys Gly Leu Cys Gln His Glu Ala Gln Pro Ala Val
         115                 120                 125            
 Ser Thr Ser Arg Gly Thr Arg Ser Ile Glu Glu Glu Tyr Gln Leu Glu
     130                 135                 140                
 Gln Leu Pro Val Pro Ser Ala His Ser Thr Gly Arg Gly Asp Arg Ser
 145                 150                 155                 160
 Ser Leu Lys Ser His
                 165



      <210> 1184
      <211> 81
      <212> PRT
      <213> Homo sapiens


      <400> 1184
 Met Ser Arg Ser Ser Lys Val Val Leu Gly Leu Ser Val Leu Leu Thr
   1               5                  10                  15    
 Ala Ala Thr Val Ala Gly Val His Val Lys Gln Gln Trp Asp Gln Gln
              20                  25                  30        
 Arg Leu Arg Asp Gly Val Ile Arg Asp Ile Glu Arg Gln Ile Arg Lys
          35                  40                  45            
 Lys Glu Asn Ile Arg Leu Leu Gly Glu Gln Ile Ile Leu Thr Glu Gln
      50                  55                  60                
 Leu Glu Ala Glu Arg Glu Lys Met Leu Leu Ala Lys Gly Ser Gln Lys
  65                  70                  75                  80
 Ser
    



      <210> 1185
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1185
 Met Gly Arg Val Ser Gly Leu Val Pro Ser Arg Phe Leu Thr Leu Leu
   1               5                  10                  15    
 Ala His Leu Val Val Val Ile Thr Leu Phe Trp Ser Arg Asp Ser Asn
              20                  25                  30        
 Ile Gln Ala Cys Leu Pro Leu Thr Phe Thr Pro Glu Glu Tyr Asp Lys
          35                  40                  45            
 Gln Asp Ile Gln Leu Val Ala Ala Leu Ser Val Thr Leu Gly Leu Phe
      50                  55                  60                
 Ala Val Glu Leu Ala Gly Phe Leu Ser Gly Val Ser Met Phe Asn Ser
  65                  70                  75                  80
 Thr Gln Ser Leu Ile Cys Ile Leu Ser Ala Cys Pro Pro Phe Pro His
                  85                  90                  95    
 Asp Pro Leu Leu Ser Gly Leu Pro Ser Ala Thr
             100                 105        



      <210> 1186
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1186
 Met Gln Leu Gln Gly Leu Ser Asn Tyr Cys Lys Ala Gln Cys Gly Leu
   1               5                  10                  15    
 Ile Gln Ile Gln Ala Leu Leu Leu Ser Ala Leu Pro Trp Glu Val Ala
              20                  25                  30        
 Leu Tyr Cys Leu Gly Pro Glu Ser Asn Thr Gln Glu Leu Ser Asn Tyr
          35                  40                  45            
 Leu Pro Asp Phe Gly His Val
      50                  55



      <210> 1187
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1187
 Met Leu Leu Leu Pro Trp Leu Thr Ala Gly Trp Thr Leu Ile Leu Cys
   1               5                  10                  15    
 Thr Asp Leu Pro Thr Pro Gln Met Pro Leu Pro Tyr Trp His Tyr Arg
              20                  25                  30        
 Pro Tyr Arg His Leu Thr Ala Pro Arg Asp Gln Thr Val Thr Asp Cys
          35                  40                  45            
 Thr Ile Val Met Ser Thr Leu Arg Glu Glu Ala Ala Leu Glu Phe Ile
      50                  55                  60                
 Thr Gln Arg Cys Pro Ala Trp Val Gly Thr Gly Lys Lys Glu Cys Ser
  65                  70                  75                  80
 Val Lys Ser Asn Leu Val Val Pro Ser Asp Lys His Leu Pro Ile Thr
                  85                  90                  95    
 Gly Ala Ser Thr Thr Val Ala Gly Leu Leu Ile Gln Ala Thr Arg Leu
             100                 105                 110        
 Pro Ala Gly Ala Gly Leu Pro Gly Thr Leu Pro Thr Thr Val Ala Glu
         115                 120                 125            
 Gly Arg Thr Val Leu Glu Gly Pro Val Ser Gly Asn Glu Ile Leu Gln
     130                 135                 140                
 Ile
 145



      <210> 1188
      <211> 209
      <212> PRT
      <213> Homo sapiens


      <400> 1188
 Met Leu Pro Val Ala Pro Val Trp Val Cys Gly Cys Ala Ala Ser Leu
   1               5                  10                  15    
 Ala Ala Glu Ala Ala His Gly Phe Leu Gln Gly Arg Asp Trp Ala Val
              20                  25                  30        
 Gly Val Lys Trp Ser Arg Lys Ala Gln Ala Ala Phe Pro Gly Arg Arg
          35                  40                  45            
 Glu Ser Ile Thr Glu Thr Arg Val Ala Glu Ala Ala His Val Ser Lys
      50                  55                  60                
 Pro Gln Met Ala Arg Ser Ala Gly Glu Thr Leu Arg Asp His Gly Ala
  65                  70                  75                  80
 Arg Gly Asn Cys Lys Ala Gly Arg Gly Thr Arg Pro Ser Tyr Cys Pro
                  85                  90                  95    
 Glu Ala Leu Val Met Ala Gly Ala Arg Leu Ala Arg Ala Tyr Asn Gly
             100                 105                 110        
 Cys Leu Glu Glu Ala Gly Arg Pro Gln Arg Trp Phe Val Thr Leu Arg
         115                 120                 125            
 Arg Ala Met Val Thr Ser Pro Asp Ala Phe Trp Ser Trp Gln Ala Lys
     130                 135                 140                
 Cys Gln Gly His Gln Arg Glu Gly Lys Glu Phe Glu Leu Asp Phe Phe
 145                 150                 155                 160
 Asp Leu Gln Pro Asn Ala Ser Ser Leu Ile Tyr Ser Cys Thr Arg Val
                 165                 170                 175    
 Tyr Ile Leu Ser Glu Cys Leu Arg Glu Cys Gly Glu Gly Ile Pro Ala
             180                 185                 190        
 Lys Gln Ser Glu Gly Tyr Ala Ser Pro Ser Asp Gln Leu Leu Ala Ser
         195                 200                 205            
 Leu
    



      <210> 1189
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1189
 Met Glu Leu Ala Ile Leu Val Leu Ile Val Arg Val Ile Ile His Leu
   1               5                  10                  15    
 Asn Ile Glu Lys Gly Pro Gln Arg Lys Lys Lys Pro Glu Cys Arg Thr
              20                  25                  30        
 Ala His Ala Ile Gln Gln Val Lys Phe Met Lys His Val Thr Val Thr
          35                  40                  45            
 Cys Arg His Gly Thr Val Trp Val Val Ser Pro Ile Val Lys Pro Ala
      50                  55                  60                
 Pro Asp Ile Val Leu Ala Ala Gly Arg Asn Arg Thr Val Glu Val Phe
  65                  70                  75                  80
 Asp Leu Asn Ala Gly Cys Ser Ala Ala Val Ile Ala Glu Ala His Ser
                  85                  90                  95    
 Arg Pro Val His Gln Ile Cys Gln Asn Lys Val Ser Lys Phe Leu Asp
             100                 105                 110        
 Asn Met Tyr His Leu
         115        



      <210> 1190
      <211> 432
      <212> PRT
      <213> Homo sapiens


      <400> 1190
 Met Trp Met Leu Leu Pro Ala Leu Val Leu Cys Leu Asp Pro Gln Gly
   1               5                  10                  15    
 Pro Pro Arg Pro Gly Leu Tyr Ser Gln Thr Pro Arg Leu Leu Gly Gly
              20                  25                  30        
 Pro Asp Lys Gly Val Val Tyr Gly Leu Asp Asp Glu Val Gln Val Gln
          35                  40                  45            
 Gly Val Leu Asn Gln Val Leu Gly Val Ala Pro Leu Gln Val Gly Val
      50                  55                  60                
 Arg Gln Glu Val Ala Gly Leu Leu Ala Ala Leu Val Glu Ala Val Gly
  65                  70                  75                  80
 Val Ala Asp Gln Gln Ala Ala Leu Leu Ala Arg Pro His Gln His Arg
                  85                  90                  95    
 Leu Leu Glu Ala His Ala Arg Arg Val Ala Ala Ala Ala Gly Arg Arg
             100                 105                 110        
 His His Gln Pro Arg Ser Ala Val Leu Arg Ala Arg Gly Gly Gln Ser
         115                 120                 125            
 Ser Ala Arg Gly Val Arg Val Asn Gly Pro Gln Ala Asp Gly Gln Pro
     130                 135                 140                
 Ala Arg Arg Glu Glu His Val Pro Gly Asp Pro Ala Ala Arg Val Val
 145                 150                 155                 160
 Ala Thr Arg Ala Gln Leu Arg Leu Glu Ala Gly Ala Ala Val Val Ala
                 165                 170                 175    
 Gly Arg Val Val Asp Asp Pro Arg Gly Ala Pro Gly Gly Arg Glu Val
             180                 185                 190        
 Val Ala Gly Gln Glu Gly Ala Ala Val Asp Val Glu Glu Leu Gly Val
         195                 200                 205            
 Val Gln Arg Arg Arg Gly Val Glu Leu Val Gly Leu Gln Gln Glu Val
     210                 215                 220                
 Gly His Arg Gly Ala Val Ala Arg Gln Gly Cys Arg Ala Arg Leu Gln
 225                 230                 235                 240
 Leu Glu Gln Leu Cys Arg Trp Asp His Gly Val Ala Tyr Gly Ala Gln
                 245                 250                 255    
 Arg Pro Leu Gly His Gly Arg Gly Arg Pro Arg Ala Thr Gln Pro Gly
             260                 265                 270        
 Leu Gln Arg Val Glu Gln Leu Gln Phe Ile Leu Gln His Gln Val Arg
         275                 280                 285            
 Ala Leu Gln Glu Leu Pro Glu Gln Leu Gly Ala His Gly Ala Pro Leu
     290                 295                 300                
 Gly Ala Gly Arg His Gly Arg Gln Val Pro Gly Gln Glu Leu Gln Ala
 305                 310                 315                 320
 Ala Leu Ala Gln Gly Leu Val Pro Gly Ala His Arg Val Val Val Pro
                 325                 330                 335    
 Ala His Arg Arg Ala Arg Ala Ser Arg Gln Val Arg Ala His Val Val
             340                 345                 350        
 Gly His Ala Ala Leu Gln Gly Gly His Ala Val Leu Gly Gly Gln Ser
         355                 360                 365            
 Val Gln Gly Asp Gly Leu Gly Gln Gln His Gly Gln Leu Pro Ala Val
     370                 375                 380                
 Gln Val Pro Ala Gly Glu Thr Glu Arg Trp Gly Gly Val Arg Ala Val
 385                 390                 395                 400
 Pro Thr Ser Gln Asp Arg Phe Phe Arg Val His Arg Gly Pro Gly Leu
                 405                 410                 415    
 Glu Leu Glu Leu His Cys Pro Gly Ala Asn Thr Val Glu Ala Pro Pro
             420                 425                 430        





      <210> 1191
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1191
 Met Leu Arg Ser Cys Ala Ala Arg Leu Arg Thr Leu Gly Ala Leu Cys
   1               5                  10                  15    
 Leu Pro Pro Val Gly Arg Arg Leu Pro Gly Ser Glu Pro Arg Pro Glu
              20                  25                  30        
 Leu Leu His Gln Ala Ala Asn Ile Ser Gly Phe Gln Thr Leu Leu Lys
          35                  40                  45            
 Gly Ser Glu Lys Gly Lys Ser Lys Val Val Gly Gly Gly Gln Gly Asn
      50                  55                  60                
 Arg Gln Ile Ala Lys Gly His Thr Asp Thr Lys Pro Glu Arg Thr His
  65                  70                  75                  80
 Ser Leu Ser Gln Asp Glu Ser Gly Pro Cys Arg Ala Lys Arg Ser Tyr
                  85                  90                  95    
 Ala Met Gly Leu Gln Ala Thr Pro Pro Arg Thr
             100                 105        



      <210> 1192
      <211> 166
      <212> PRT
      <213> Homo sapiens


      <400> 1192
 Met Ser Phe Thr Val Ser Met Ala Ile Gly Leu Val Leu Gly Gly Phe
   1               5                  10                  15    
 Ile Trp Ala Val Phe Ile Cys Leu Ser Arg Arg Arg Arg Ala Ser Ala
              20                  25                  30        
 Pro Ile Ser Gln Trp Ser Ser Ser Arg Arg Ser Arg Ser Ser Tyr Thr
          35                  40                  45            
 His Gly Leu Asn Arg Thr Gly Phe Tyr Arg His Ser Gly Cys Glu Arg
      50                  55                  60                
 Arg Ser Asn Leu Ser Leu Ala Ser Leu Thr Phe Gln Arg Gln Ala Ser
  65                  70                  75                  80
 Leu Glu Gln Ala Asn Ser Phe Pro Arg Lys Ser Ser Phe Arg Ala Ser
                  85                  90                  95    
 Thr Phe His Pro Phe Leu Gln Cys Pro Pro Leu Pro Val Glu Thr Glu
             100                 105                 110        
 Ser Gln Leu Val Thr Leu Pro Ser Ser Asn Ile Ser Pro Thr Ile Ser
         115                 120                 125            
 Thr Ser His Ser Leu Ser Arg Pro Asp Tyr Trp Ser Ser Asn Ser Leu
     130                 135                 140                
 Arg Val Gly Leu Ser Thr Pro Pro Pro Pro Ala Tyr Glu Ser Ile Ile
 145                 150                 155                 160
 Lys Ala Phe Pro Asp Ser
                 165    



      <210> 1193
      <211> 246
      <212> PRT
      <213> Homo sapiens


      <400> 1193
 Met Ala Ala Ala Ala Ile Pro Ala Leu Leu Leu Cys Leu Pro Leu Leu
   1               5                  10                  15    
 Phe Leu Leu Phe Gly Trp Ser Arg Ala Arg Arg Asp Asp Pro His Ser
              20                  25                  30        
 Leu Cys Tyr Asp Ile Thr Val Ile Pro Lys Phe Arg Pro Gly Pro Arg
          35                  40                  45            
 Trp Cys Ala Val Gln Gly Gln Val Asp Glu Lys Thr Phe Leu His Tyr
      50                  55                  60                
 Asp Cys Gly Asn Lys Thr Val Thr Pro Val Ser Pro Leu Gly Lys Lys
  65                  70                  75                  80
 Leu Asn Val Thr Met Ala Trp Lys Ala Gln Asn Pro Val Leu Arg Glu
                  85                  90                  95    
 Val Val Asp Ile Leu Thr Glu Gln Leu Leu Asp Ile Gln Leu Glu Asn
             100                 105                 110        
 Tyr Thr Pro Lys Glu Pro Leu Thr Leu Gln Ala Arg Met Ser Cys Glu
         115                 120                 125            
 Gln Lys Ala Glu Gly His Ser Ser Gly Ser Trp Gln Phe Ser Ile Asp
     130                 135                 140                
 Gly Gln Thr Phe Leu Leu Phe Asp Ser Glu Lys Arg Met Trp Thr Thr
 145                 150                 155                 160
 Val His Pro Gly Ala Arg Lys Met Lys Glu Lys Trp Glu Asn Asp Lys
                 165                 170                 175    
 Asp Val Ala Met Ser Phe His Tyr Ile Ser Met Gly Asp Cys Ile Gly
             180                 185                 190        
 Trp Leu Glu Asp Phe Leu Met Gly Met Asp Ser Thr Leu Glu Pro Ser
         195                 200                 205            
 Ala Gly Ala Pro Leu Ala Met Ser Ser Gly Thr Thr Gln Leu Arg Ala
     210                 215                 220                
 Thr Ala Thr Thr Leu Ile Leu Cys Cys Leu Leu Ile Ile Leu Pro Cys
 225                 230                 235                 240
 Phe Ile Leu Pro Gly Ile
                 245    



      <210> 1194
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1194
 Met Asn Leu Lys Lys Leu Leu Leu Leu Gln Thr Asn Gly Leu Trp Gly
   1               5                  10                  15    
 Thr Val Leu Pro Phe Arg Lys Glu Arg Val Phe Asn Asp Glu Lys Glu
              20                  25                  30        
 Val Ser Leu Asn Gly Glu Asp Asp Tyr Val Thr Glu Glu Val Glu Gly
          35                  40                  45            
 Leu Lys Met Asp Ser Ala Leu Gly Pro Cys Arg Asp Cys Lys Thr Pro
      50                  55                  60                
 Cys Thr Thr
  65        



      <210> 1195
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1195
 Met Lys Pro Arg Thr Leu Thr Val Leu Gln Phe Leu Met Met Val Trp
   1               5                  10                  15    
 Leu Gly Phe Val Pro Ser Val Val Gln Thr Tyr Pro Glu Phe Pro Pro
              20                  25                  30        
 Ser Gly Gly Phe Thr Val Ser Leu Thr Pro Gly Val Asn Leu Gln Ile
          35                  40                  45            
 Phe Thr Met Ile Val Thr Val His Lys Ser Asn Ala Ser Gly Val Val
      50                  55                  60                
 Cys Ser Ser Trp Trp Val Pro Gly Leu Ala Asp Phe Arg Ser Glu Ala
  65                  70                  75                  80
 Ala Asp Leu Leu Val Lys Gly Phe Lys Glu Ala Ile Asn Gln Tyr Gly
                  85                  90                  95    
 Pro Gly Ser Pro Phe Val Met Gly Leu Leu Lys Asn Val Ala Val Ser
             100                 105                 110        
 Ser Arg Met Ile Pro Thr Asp Trp Asp Ala Leu Thr Arg Ala Cys Leu
         115                 120                 125            
 Thr Pro Ala Gln Phe Leu Gln Phe Lys Thr Trp Trp Ala Asp Glu Ala
     130                 135                 140                
 Ser Ile Gln Ala Ala Cys Asn Ala Gln Ala Gln Pro Gln Ile Asn Ile
 145                 150                 155                 160
 Thr Ala Asp Gln Leu Leu Gly Ile Gly Ser Trp Ala Gly
                 165                 170            



      <210> 1196
      <211> 206
      <212> PRT
      <213> Homo sapiens


      <400> 1196
 Met Pro Thr Pro Glu Ser Leu Glu Leu Leu Pro Met Leu Leu His Met
   1               5                  10                  15    
 Ala Asn Gly Thr Leu Trp Leu Cys Leu Gln Ile Leu Arg Cys Gly Asp
              20                  25                  30        
 Asp Pro Gly Ser Pro Gly Gly Ala Ser Val Ile Thr Arg Val Leu Leu
          35                  40                  45            
 Ser Glu Arg Glu Ala Gly Lys Ser Glu Ser Glu Asn Gly Arg Ser Glu
      50                  55                  60                
 Asn Arg Ser Arg Gly Phe Asn Leu Glu Glu Leu Arg Ser Pro Gln Arg
  65                  70                  75                  80
 Phe Tyr Gln Ser Glu Leu Ala Ser Leu Ala Tyr His Ser Ala Asn Asp
                  85                  90                  95    
 Thr His Ala Ser Ser Leu Pro His Leu Gln Lys Leu Val Val Gln Thr
             100                 105                 110        
 Arg Thr Val Glu Glu Ile Ile Leu Phe Pro Gln Leu Ser Ile Pro Leu
         115                 120                 125            
 Gln Phe His Ser Cys Pro Met Thr Asp Phe Thr Lys Pro Gly Phe Ala
     130                 135                 140                
 Ala Met Leu Arg Val Ser Glu Leu Gly Arg Asp Gly Ser His Thr Ala
 145                 150                 155                 160
 Arg Gly Arg Ile His Pro Lys Gly Val Ser Glu Glu Ala Asn Leu Leu
                 165                 170                 175    
 Arg Ala Leu Phe Val Met Gln Pro Asn Leu Ala Arg Leu Thr Glu Tyr
             180                 185                 190        
 Pro Val Ile Ser Ser Pro Ala Tyr Val Phe Glu Phe Ile Ser
         195                 200                 205    



      <210> 1197
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 1197
 Met Lys Val Ser Ala Ala Leu Leu Cys Leu Leu Leu Met Ala Ala Thr
   1               5                  10                  15    
 Phe Ser Pro Gln Gly Leu Ala Gln Pro Val Leu Gly Gly Asp Ser Gly
              20                  25                  30        
 Ala Ala Thr Ala Thr Thr Leu Pro Leu Phe Gly Glu Ile Ile Gln Asn
          35                  40                  45            
 Glu Glu Leu Phe Leu Thr Val Gly Val Lys Asp Ile Ser Gly Arg Ser
      50                  55                  60                
 Gly Glu Gly Glu Thr Ile Ala
  65                  70    



      <210> 1198
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 1198
 Met Met Arg Thr Gln Cys Leu Leu Gly Leu Arg Thr Phe Val Ala Phe
   1               5                  10                  15    
 Ala Ala Lys Leu Trp Ser Phe Phe Ile Tyr Leu Leu Arg Arg Gln Ile
              20                  25                  30        
 Arg Thr His Met Gln Pro Glu Ile Ala Arg Leu Asp Thr Gly Ala Leu
          35                  40                  45            
 Ser Asp Leu Ile Met Ala Gln Gly Glu Lys Lys Gly Arg Ser
      50                  55                  60        



      <210> 1199
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1199
 Met Leu Val Val Ala Phe Gly Leu Leu Val Leu Tyr Ile Leu Leu Ala
   1               5                  10                  15    
 Ser Ser Trp Lys Arg Pro Glu Pro Gly Ile Leu Thr Asp Arg Gln Gly
              20                  25                  30        
 Pro Ser Pro Ser Asp His Ser Ala Ala His His Ala Ala Asp Ala Lys
          35                  40                  45            
 Val Val Val Ser Ser Val Gln Gln Pro Trp Glu Pro Leu Pro Pro Ser
      50                  55                  60                
 Glu Gly Phe Leu Ala Glu Thr His Ile Ala Ser Pro Gly Pro Thr Met
  65                  70                  75                  80
 Ala Ala Cys Leu Ala Gln Pro Ser Val Leu Cys His Ala Arg Ala
                  85                  90                  95



      <210> 1200
      <211> 123
      <212> PRT
      <213> Homo sapiens


      <400> 1200
 Met Ala Ile Ile Thr Val Asn Cys Lys Ala Leu Met Met Thr Ile Glu
   1               5                  10                  15    
 Arg Gln Ile Asp Leu Phe Leu Leu Ile Val Thr Val Leu Asn Val Ala
              20                  25                  30        
 Gly Val Met Gly Thr Gln Ile Ser His Leu Val Met Ala Leu Pro Gly
          35                  40                  45            
 Trp Met Leu Ala Gln Leu Gly Pro Asp Ala Ser Ile Asn Leu Arg His
      50                  55                  60                
 Ser Ala Val Glu Ile Lys Val Arg Asn Cys Leu Asn Trp Cys Trp Ser
  65                  70                  75                  80
 Arg Leu Val Ser Met Gly Tyr Gln Phe Ser Arg Glu Cys Gly Arg Gln
                  85                  90                  95    
 Phe His Leu Leu Pro Ala Tyr Ala Ala Asn Ser Pro Ser Tyr Thr Ser
             100                 105                 110        
 Ser His Asp Leu Ser Ser Ser Leu Gln Thr His
         115                 120            



      <210> 1201
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1201
 Met Val His Ile Ser Arg Leu Pro Gly Gly Phe Leu Ile Leu Gln Glu
   1               5                  10                  15    
 Val Arg Lys Lys Gly Lys Leu Lys His Ser Thr Gly Lys Leu Glu Leu
              20                  25                  30        
 Lys Ala Ala His Pro Trp Arg Ile Met Gly Pro Glu Asp Glu Ala Ala
          35                  40                  45            
 Gln Ser Val Asp Ser Ile Thr Asn Gln Thr Ser Leu Leu Ile Pro Val
      50                  55                  60                
 Pro Pro Gln Trp Pro Leu Thr His Ile Asp Gly Ala Ser Asp Cys Leu
  65                  70                  75                  80
 Gly Leu Val Pro Pro Met Pro Arg Lys
                  85                



      <210> 1202
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 1202
 Met Pro Phe Val Met Ser Ser Asn Thr Leu Thr Leu Met Ala Phe Met
   1               5                  10                  15    
 Pro Leu Ser Leu Ser Leu Asn Trp Arg Ala Thr Ser Ile Pro Asp Pro
              20                  25                  30        
 Arg Thr Leu Gln Lys Ser His Lys Ser Lys Leu His His Arg Tyr Asp
          35                  40                  45            
 Pro Thr Pro Trp Glu Ser Tyr His Ser Met Lys Asn Phe Arg Gln Asp
      50                  55                  60                
 Leu Val His Ser Arg Phe Leu Pro Ile Ala Asn Glu Ala Glu Val Ser
  65                  70                  75                  80
 Leu Ser Val Lys Glu Ile Asn Ile Gly Tyr Gln Glu Pro Gln Arg Leu
                  85                  90                  95    
 Ile Leu Ser
            



      <210> 1203
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1203
 Met Ser Pro Cys Ile Ser Phe Ala Thr Ala Phe Ser Phe Val Ile Tyr
   1               5                  10                  15    
 Tyr Leu Leu Gly Ser Ser Ser Leu Ile His Gly Tyr Ala Tyr Leu Ile
              20                  25                  30        
 Val Phe Lys Asp Asp Cys Ser Lys Ile Cys Arg Gln Ala Leu Lys Phe
          35                  40                  45            
 Leu Met Gln Ile Trp Ala Gln Pro Leu Ile Asn Leu Gln Met Ala Asn
      50                  55                  60                
 Ala Ser Leu Tyr Glu His Val Glu Arg Met His Leu Ile Gly Lys Ser
  65                  70                  75                  80
 Trp Glu Gln Leu Lys Leu Leu Gly Asp Tyr Leu Gly Pro Cys Trp Ser
                  85                  90                  95    
 Gly Ala Leu Lys Glu Leu Arg Arg Arg Ala Gly Leu Asp Ser Ala Ser
             100                 105                 110        
 Leu Lys Thr Ala Ser Ser Ile Leu Ala Ala Val Leu Pro Glu Pro Gly
         115                 120                 125            
 Phe Leu Gly Ala Arg Tyr Asn Leu Leu Leu Glu Met Ile Lys Ala Asn
     130                 135                 140                
 Tyr Ile Thr Leu Gly Thr Asn Pro Leu
 145                 150            



      <210> 1204
      <211> 52
      <212> PRT
      <213> Homo sapiens


      <400> 1204
 Met Ala Arg Ser Arg Trp Ser Leu Ser Ser Glu Leu Leu Gly Phe Phe
   1               5                  10                  15    
 Leu Ala Asn Cys Val Ser Phe Phe Asn Cys Ala His Val Gly Gly Ser
              20                  25                  30        
 Ala Phe Leu Val Asp Gly Asn Phe Ile Cys Ser Ser Asp Ile Thr Ile
          35                  40                  45            
 Leu Phe Ile Leu
      50        



      <210> 1205
      <211> 85
      <212> PRT
      <213> Homo sapiens


      <400> 1205
 Met Pro Leu Asp Leu Leu Leu Ser Met Gln Pro Pro Ala Val Phe Leu
   1               5                  10                  15    
 Leu Val Pro Gly Ile Asp Pro Thr Lys Pro Tyr Ala Ser Pro Leu Gly
              20                  25                  30        
 Lys Leu Lys Thr Arg Gln Pro Ser Glu Leu Ala Arg Ala Ala Ser Pro
          35                  40                  45            
 Gln Leu Ser Ser Gln Glu Pro Ser Val Ala Ser Thr Ala Trp Ala Ala
      50                  55                  60                
 Gly Gly Leu Gly Arg Pro Leu Ile Leu Thr Ser Thr Arg Ala Glu Ala
  65                  70                  75                  80
 Ala Ser Phe Asp Val
                  85



      <210> 1206
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1206
 Met Pro Leu Pro Leu Glu Pro Leu Gly Cys Val Gln Leu Leu Val Leu
   1               5                  10                  15    
 Gln Val Ser Thr Ser Asp His Thr Lys Arg Cys Pro Pro Pro Thr Leu
              20                  25                  30        
 Pro Ser Ala Thr Thr His Ile Arg Arg Leu Gly Thr His Ser Ser Leu
          35                  40                  45            
 Pro Pro Ser Gly Thr Asp Pro Glu Arg Glu Cys Asn Arg Ser Asn Asn
      50                  55                  60                
 Ile Thr Ser Glu Met Arg Leu Gln Gly Gln Asn Asp Ala Cys Leu Gly
  65                  70                  75                  80
 His Pro Ser Pro Ala Leu Ser Ile Ala Pro Ser Asp Gly Ser Gln Leu
                  85                  90                  95    
 Pro Cys Asp Glu Val Pro Tyr Gly Glu Ala His Val Thr Arg Tyr Cys
             100                 105                 110        
 Lys Ser Pro Leu Thr Asn Ser His Leu Glu Thr Glu Ala Gln Tyr Asn
         115                 120                 125            
 Ser Leu
     130



      <210> 1207
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1207
 Met Met Val Ile Thr Phe Thr Glu Tyr Leu Leu Cys Thr Cys Ala Glu
   1               5                  10                  15    
 Cys Tyr Leu Val Leu Ile Gly Thr Met Thr Gly Glu Glu Asp Leu Ser
              20                  25                  30        
 Val Glu Glu Asp Glu Glu Val Leu Thr Leu Leu Tyr Asp Pro Cys Leu
          35                  40                  45            
 Asn Cys Tyr Phe Asp Pro Gln Thr Gly Lys Tyr Tyr Glu Leu Val
      50                  55                  60            



      <210> 1208
      <211> 312
      <212> PRT
      <213> Homo sapiens


      <400> 1208
 Met Ala Leu Arg Leu Val Ile Pro Ala Leu Trp Glu Ala Glu Leu Val
   1               5                  10                  15    
 Gly Ala Leu Met Leu Ala Ala Leu Ser His Leu His Arg Phe Leu Leu
              20                  25                  30        
 Ser Met Trp Val Leu Pro Pro Gly Thr Phe Thr Asp Ala Phe Pro Gly
          35                  40                  45            
 Leu Leu Phe His Phe Pro Arg Arg Ser Gln Lys Asp Cys Leu Leu Gly
      50                  55                  60                
 Leu Ser Lys Ser Asp Gln Arg Ala Met Ala Cys Tyr Phe Gly Ile Leu
  65                  70                  75                  80
 Leu Ile Val Ser Ala Thr Leu Cys Phe Gly Met Asn Tyr Tyr Leu Asp
                  85                  90                  95    
 Glu Phe Ala Asn Leu Leu Asp Glu Leu Leu Met Lys Ile Asn Gly Leu
             100                 105                 110        
 Ser Asp Ser Leu Gln Leu Pro Leu Leu Glu Lys Thr Ser Asn Asn Thr
         115                 120                 125            
 Gly Glu Ala Arg Thr Glu Glu Ser Pro Leu Val Asp Ile Ser Ser Tyr
     130                 135                 140                
 Gln Ala Ala Glu Met Val Met Met Ala Arg Thr Leu Ala Thr Cys Leu
 145                 150                 155                 160
 Gln His Ala Gln Gly Leu Gly Phe Glu Ala Cys Leu Pro Ile Leu Ser
                 165                 170                 175    
 Ala Pro His Ala Leu Ser His Trp Thr Leu Thr Thr Cys Leu Trp Gln
             180                 185                 190        
 Leu Gly Phe Met Ser Ala Val Leu Ile Leu Lys Tyr Thr Arg Ala Leu
         195                 200                 205            
 Leu Ala Gln Gly Gln Phe Ser Gly Pro Phe Val Ile Asp Lys Gly Val
     210                 215                 220                
 Arg Leu Glu Leu Ile Gly Leu Ile Ser Arg Val Trp Glu Val Ser Glu
 225                 230                 235                 240
 Gln Glu Asn Ser Lys Glu Glu Val Tyr Arg His Glu Glu Gly Ile Thr
                 245                 250                 255    
 Val Ile Ser Asp Leu Leu Leu Gly Arg Gln Trp Gln Gln Gly His Lys
             260                 265                 270        
 Gly Ile Cys Leu Gln Leu Met Leu Pro Phe Ser Arg Gly Lys His Arg
         275                 280                 285            
 Thr Ser Gly Ala Phe Leu Met Phe Ser Leu Glu Leu Phe Thr Val Ala
     290                 295                 300                
 Gln Leu Val Pro Ile Ser Gly Ser
 305                 310        



      <210> 1209
      <211> 228
      <212> PRT
      <213> Homo sapiens


      <400> 1209
 Met Ala Arg Pro Pro Arg Gln His Pro Gly Val Trp Ala Ser Leu Leu
   1               5                  10                  15    
 Leu Leu Leu Leu Thr Gly Pro Ala Ala Cys Ala Ala Ser Pro Ala Asp
              20                  25                  30        
 Asp Gly Ala Gly Pro Gly Gly Arg Gly Pro Arg Gly Arg Ala Arg Gly
          35                  40                  45            
 Asp Thr Gly Ala Asp Glu Ala Val Pro Arg His Asp Ser Ser Tyr Gly
      50                  55                  60                
 Thr Phe Ala Gly Glu Phe Tyr Asp Leu Arg Tyr Leu Ser Glu Glu Asp
  65                  70                  75                  80
 Ser Thr Thr Ile Arg Trp Val Leu Val Glu Ile Tyr Gly Lys Pro Gly
                  85                  90                  95    
 Cys Asn Ala Glu Thr Cys Asp Tyr Phe Leu Ser Tyr Arg Met Ile Gly
             100                 105                 110        
 Ala Asp Val Glu Phe Glu Leu Ser Ala Asp Thr Asp Gly Trp Val Ala
         115                 120                 125            
 Val Gly Phe Ser Ser Asp Lys Lys Met Gly Gly Asp Asp Val Met Ala
     130                 135                 140                
 Cys Val His Asp Asp Asn Gly Arg Val Arg Ile Gln His Phe Tyr Asn
 145                 150                 155                 160
 Val Gly Gln Trp Ala Lys Glu Ile Gln Arg Asn Pro Ala Arg Asp Glu
                 165                 170                 175    
 Glu Gly Val Phe Glu Asn Asn Arg Val Thr Cys Arg Phe Lys Arg Pro
             180                 185                 190        
 Val Asn Val Pro Arg Asp Glu Thr Ile Val Asp Leu His Leu Ser Trp
         195                 200                 205            
 Tyr Tyr Leu Phe Ala Trp Gly Pro Ala Ile Gln Gly Lys Leu Thr Phe
     210                 215                 220                
 Gln His Leu Asp
 225            



      <210> 1210
      <211> 104
      <212> PRT
      <213> Homo sapiens


      <400> 1210
 Met Trp Val Leu Asp Val Arg Phe Leu Val Asn Met Tyr His Phe Leu
   1               5                  10                  15    
 Thr Ile Ile Arg Ser Gln Asn Pro Lys Leu Asn Asn Leu Lys Val Lys
              20                  25                  30        
 Arg Asn Val Thr Pro Lys Ile Ala Leu Leu Pro Phe Thr Lys His Glu
          35                  40                  45            
 Asp Gly Lys Ala Lys Glu Tyr Leu Arg Asn Asn Ser Leu Met Ile Leu
      50                  55                  60                
 Gln Lys Leu Ser Pro Lys Thr Asp Asp Leu Val Leu Val Gln Lys Arg
  65                  70                  75                  80
 Gln Thr His Gly Asn Lys Phe Cys Val Glu Leu Leu His Asp Ile Asp
                  85                  90                  95    
 Ala Val Ser Thr Glu Ser Ser Trp
             100                



      <210> 1211
      <211> 460
      <212> PRT
      <213> Homo sapiens


      <400> 1211
 Met His Ala Ala Ala Asn Gln Thr Pro Gly Ser Arg Ala Trp Ala His
   1               5                  10                  15    
 Gln Arg Gln Cys Gly Val Gln Gly Leu Leu Val Leu Trp Ser His Pro
              20                  25                  30        
 Leu Met Leu Val Ser Thr Tyr Pro Ser Val Ser Pro Glu Val Asp Ser
          35                  40                  45            
 Val Gly Ser Trp Ser Asp Pro Ala Gly Cys Asp Pro Gln Asp Arg Met
      50                  55                  60                
 Val Leu Asp Ser Gly Ser Gln Ala Tyr Asp Gln Ala Pro Thr Ser Pro
  65                  70                  75                  80
 Pro Thr Ser Leu Leu Ser Leu Arg His Arg Leu Lys His Ser Asp Arg
                  85                  90                  95    
 Asp Gly Pro Pro Leu Tyr Pro Trp Ser Gln Ser Leu Ala Leu Pro Val
             100                 105                 110        
 Ala Leu Ala Val Pro Pro Ala Leu Gln Pro Gln Pro Glu Gln Gln Ser
         115                 120                 125            
 Phe Ser Gln Met His Leu Gly His Arg Gly His Met Arg Arg Ser Glu
     130                 135                 140                
 Ser Thr Tyr Ser Val Asn Ser Thr Gly Arg Arg Gly Arg Gly Thr Leu
 145                 150                 155                 160
 Gly Gln Pro Pro Pro Gly Arg Arg Trp Asn Pro Gly Pro Ala Ser Gln
                 165                 170                 175    
 Gly Thr Gly Thr Asp Cys Cys Ala Pro Pro Asp Trp Val Arg Glu Ala
             180                 185                 190        
 Pro Pro Met Gly Leu Ser Phe Ser Gly Met Gln Gly Ile Leu Pro Ala
         195                 200                 205            
 Pro Arg Val Ser His Gly Ser Thr Pro Ser Ser Gly His Gln Ser Pro
     210                 215                 220                
 Gln Glu Lys Gly Ser Arg Pro Pro Pro Gly Pro Ser Glu Lys Gln Thr
 225                 230                 235                 240
 Ala Arg Met Leu Lys Glu His Gln Gly Asp Arg Asn Thr Gln Thr Val
                 245                 250                 255    
 Glu Ala Gln Ser Lys Gln Leu His Val Leu Gly Ala Tyr Leu Glu Leu
             260                 265                 270        
 Leu Ser Arg Ala Ser Val Cys Ser Pro Gln Pro Thr Ser Val Gly Gln
         275                 280                 285            
 Gln Ala Thr Gln Leu Arg His Ile Gln Pro Val Gly Gly His Asp Val
     290                 295                 300                
 Leu Gln Leu Leu Pro Val Ala Cys Gln Val Leu His Lys Asn Ala Gln
 305                 310                 315                 320
 Asp Ala Val Gln Val His Leu Val Leu Ala Glu Leu Thr Trp Gln Arg
                 325                 330                 335    
 Gly Val Cys Leu Ala Ala Leu Gly Ala Arg Ala Val Leu Pro Ala Arg
             340                 345                 350        
 Ser Ala Pro Gly Pro Gly Arg Ala Gly Gly Arg Thr Asp Ala Gln Arg
         355                 360                 365            
 Gly Gly Trp Cys Ser Arg Ala Glu Gln Arg Ser Ala Pro Gln Glu Arg
     370                 375                 380                
 Leu Leu Ala Glu Gln His Ala Val Gln Val Cys Thr Ser Asp Leu Trp
 385                 390                 395                 400
 Ser Ala Asp Arg Thr Glu Ala Leu Ser Arg Gln Ser Ser Glu Asp Ser
                 405                 410                 415    
 Thr Gln Ser Arg Arg Lys Val Gln Cys Pro Ala Leu His Pro Pro His
             420                 425                 430        
 Val Thr Thr Ser Arg Leu His Asp Leu Val Val Gly Gln Asp Val Glu
         435                 440                 445            
 Ser Glu Gly Ser Asp Thr Asp Asp Pro Asn Pro Val
     450                 455                 460



      <210> 1212
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1212
 Met Lys Val Leu Leu Leu Thr Gly Leu Gly Ala Leu Phe Phe Ala Tyr
   1               5                  10                  15    
 Tyr Trp Asp Asp Asn Phe Asp Pro Ala Ser Leu Gln Gly Ala Arg Val
              20                  25                  30        
 Leu Leu Thr Gly Ala Asn Ala Gly Val Gly Glu Glu Leu Ala Tyr His
          35                  40                  45            
 Tyr Ala Arg Leu Gly Ser His Leu Val Leu Thr Ala His Thr Glu Ala
      50                  55                  60                
 Leu Leu Gln Lys Val Val Gly Asn Cys Arg Lys Leu Gly Ala Pro Lys
  65                  70                  75                  80
 Val Phe Tyr Ile Ala Ala Asp Met Ala Ser Pro Glu Ala Pro Glu Ser
                  85                  90                  95    
 Val Val Gln Phe Ala Leu Asp Lys Leu Gly Glu Gly Leu Gly Leu Lys
             100                 105                 110        
 Pro Gly Val Arg Asp Arg Gly Leu Gly Leu Arg Asp Arg Thr Arg Ile
         115                 120                 125            
 Gly Leu Trp Val Trp Pro Gln
     130                 135



      <210> 1213
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 1213
 Met Leu Phe Leu Ala Leu Leu Leu Leu Pro Val Val Val Ala Phe Ala
   1               5                  10                  15    
 Arg Ala Glu Ala Glu Glu Asp Gly Asp Leu Gln Cys Leu Ala Thr Leu
              20                  25                  30        
 Lys Asn Gly Arg Lys Ile Cys Leu Asp Leu Gln Ala Leu Leu Tyr Lys
          35                  40                  45            
 Lys Ile Ile Lys Glu His Leu Glu Ser
      50                  55        



      <210> 1214
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1214
 Met Gly Leu Gly Ala Arg Gly Ala Trp Ala Ala Leu Leu Leu Gly Thr
   1               5                  10                  15    
 Leu Gln Val Leu Ala Leu Leu Gly Ala Ala His Glu Ser Ala Ala Met
              20                  25                  30        
 Ala Gly Ala Arg Gln Leu Arg Ser Val Lys Gly Thr Ala Ala Arg Ser
          35                  40                  45            
 Pro Val Ala Leu Val Val Ala Ser Lys Val Val Thr Gly
      50                  55                  60    



      <210> 1215
      <211> 239
      <212> PRT
      <213> Homo sapiens


      <400> 1215
 Met Thr Val Met Ala Leu Leu Pro Leu Ser Thr Phe Pro Phe Cys Phe
   1               5                  10                  15    
 Phe Cys Phe Gln Trp Asn Thr Lys Ser Arg Glu Ser Ile Gln Glu Pro
              20                  25                  30        
 Arg Ser Asp Tyr Tyr Asn His Glu Val Pro Asp Ile Asp Leu Ser Asp
          35                  40                  45            
 Cys Glu Phe Pro His Val Ile Glu Ile Tyr Asp Phe Pro Gln Glu Phe
      50                  55                  60                
 His Thr Glu Asp Leu Leu Arg Val Phe Cys Ser Tyr Gln Lys Lys Gly
  65                  70                  75                  80
 Phe Asp Ile Lys Trp Val Asp Asp Thr His Ala Leu Gly Val Phe Ser
                  85                  90                  95    
 Ser Pro Ile Thr Ala Arg Asp Ala Leu Gly Ile Lys His Thr Met Val
             100                 105                 110        
 Lys Ile Arg Pro Leu Ser Gln Ala Thr Arg Ala Ala Lys Ala Lys Ala
         115                 120                 125            
 Arg Ala Tyr Ala Glu Phe Leu Gln Pro Ala Lys Glu Arg Pro Glu Thr
     130                 135                 140                
 Ser Ala Ala Leu Ala Arg Arg Leu Val Ile Ser Ala Leu Gly Val Arg
 145                 150                 155                 160
 Ser Lys Gln Ser Lys Thr Glu Arg Glu Ala Glu Leu Lys Lys Leu Gln
                 165                 170                 175    
 Glu Ala Arg Gly Phe Arg Gln Ser His Cys Leu Ser Pro Gln Phe Leu
             180                 185                 190        
 Glu Ser Val Lys Ala Ile Tyr Ser Glu Asn Ser Thr Tyr Arg Lys Val
         195                 200                 205            
 His Gln His Ala Ala Pro Leu Glu Val Phe Val Leu Asn Val Trp Leu
     210                 215                 220                
 Cys Lys Gly His Phe Ser Asp Ala Ile Lys Asn Asp Ser Val Asp
 225                 230                 235                



      <210> 1216
      <211> 288
      <212> PRT
      <213> Homo sapiens


      <400> 1216
 Met Gly Pro Glu Tyr Gln Thr Glu Lys Pro Arg Leu Trp Pro Gly Ala
   1               5                  10                  15    
 Cys Phe Gln Cys Leu Ser Leu Leu Pro Val Leu Leu Gly Arg Thr Ile
              20                  25                  30        
 Gln Ala Gly Ser Gln Val Met Arg Gly Glu Ala Leu Pro Val Val Ile
          35                  40                  45            
 Leu Pro Ala Lys Ala Arg Ala Arg Thr Asp Pro Gly Leu Thr Pro Lys
      50                  55                  60                
 Pro Met Leu Phe Arg Phe Gly Val Lys Phe Gln Asn Gln Thr Tyr Val
  65                  70                  75                  80
 Phe Val Leu Gln Leu Ala Lys Pro Gly Ala Met Glu Asn Pro Asp Ala
                  85                  90                  95    
 Cys Leu Pro Gly Arg Pro Cys Trp Ile Cys Tyr Leu Gly Pro Val Gln
             100                 105                 110        
 Ala Ile Glu Tyr Ser Tyr Ala Ile Leu Gly Pro Ser Val Gln Glu Arg
         115                 120                 125            
 Gln Arg Glu Glu Arg Gly Lys Gly Trp Glu Glu Glu Gly Arg Lys Glu
     130                 135                 140                
 Glu Arg Thr Asn Pro Cys Ile Lys Gly Ser Trp His Pro Met Val Phe
 145                 150                 155                 160
 Ala Phe Leu Glu Thr Thr Cys His Val Val Arg Lys Pro Arg His Pro
                 165                 170                 175    
 Ala Glu Lys Val Pro Cys Asp Ala Ala Ala Ala Ala Ala Ala Ser Ala
             180                 185                 190        
 Leu Gly Ser Thr Ala Leu Lys Glu Pro Thr Val Gln Thr Ala Thr Asn
         195                 200                 205            
 Gly His Leu Ile Leu Asp Phe Ser His Val Leu Pro Ala Val Gln Ser
     210                 215                 220                
 Ser Ile Pro Pro Ser Gly Gln Pro Arg Glu Lys Gly Phe Ser Val Leu
 225                 230                 235                 240
 His Gly Ala Arg Arg Arg Leu Glu Gln Ser Arg Gln Ala Val Pro Ser
                 245                 250                 255    
 Pro Asn Arg Pro Gln Gln Phe His Trp Ile Arg Pro Val Ala Glu Ser
             260                 265                 270        
 Ala Arg Ser Ala Arg Leu Leu Leu Asp Ala Arg Leu Thr Leu Met Leu
         275                 280                 285            





      <210> 1217
      <211> 49
      <212> PRT
      <213> Homo sapiens


      <400> 1217
 Met Ala Cys Asp Ser Ser Asn Ser Asn Ser Trp Lys Thr Leu Ser Ala
   1               5                  10                  15    
 Ala Ser Leu Val Thr Gly Pro Pro Trp Tyr Ile Tyr Leu Trp Pro Pro
              20                  25                  30        
 Gly Val Thr Leu Leu Phe Thr Thr Met Val Cys Glu Trp Phe Cys Gln
          35                  40                  45            
 Arg
    



      <210> 1218
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1218
 Met Arg Lys Leu Ile Ala Gly Leu Ile Phe Leu Lys Ile Trp Thr Cys
   1               5                  10                  15    
 Thr Val Arg Thr Ser Thr Asp Leu Leu Gln Thr Glu Gly Cys Ser Gln
              20                  25                  30        
 Tyr Ile His Gln Val Thr Glu Val Leu Lys Val Ser Ile Ile Gly Gln
          35                  40                  45            
 Tyr Cys Ile Ala Arg Glu Gly Lys Gly Phe Thr His Pro Val Arg Arg
      50                  55                  60                
 Leu Ser Cys Leu Arg Gln Lys Leu Tyr Asn Gly Thr Thr Lys Thr Val
  65                  70                  75                  80
 Thr Trp Trp Asn Ser Asn Tyr Thr Glu Arg Asn Pro Phe Ser Lys Phe
                  85                  90                  95    
 Pro Lys Leu Gln Thr Val Trp Ala His Pro Glu Phe His Trp Asp Trp
             100                 105                 110        
 Met Ala Pro Thr Arg Leu Tyr Trp Ile Cys Gly His Arg Ala Tyr Ala
         115                 120                 125            
 Lys Leu Pro Asp Gln Trp Thr Gly Ser Cys Val Ile Ser Thr Ile Lys
     130                 135                 140                
 Pro Ser Phe Phe Leu Leu Pro Ile Lys Thr Gly Glu Leu Leu Gly Phe
 145                 150                 155                 160
 Pro Val Tyr Ala Ser His Glu Lys Arg Ser Ile Ala Ile
                 165                 170            



      <210> 1219
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1219
 Met Ala Val Gly Leu Val Phe Lys Val Ala Arg Leu Tyr Tyr Asn Tyr
   1               5                  10                  15    
 Gly Leu Leu Leu Phe Thr Val Ala Pro Lys Cys Gly Val Glu Leu Lys
              20                  25                  30        
 Gly Lys Leu Leu Leu Leu Tyr Leu Glu Ile Gln Val Ser Gln Arg Pro
          35                  40                  45            
 Arg Glu Gln Asn Gly Phe Leu Gly Thr Leu His Gly Pro Thr Thr Gln
      50                  55                  60                
 Ile Gln Leu Arg Ile His Thr Val Leu Leu Asn Cys Pro Ile Cys Gly
  65                  70                  75                  80
 Ser Asp Trp Asp Pro Pro Val Glu Ser Gly Glu Gln Ile Phe Phe Ile
                  85                  90                  95    
 Phe Met
        



      <210> 1220
      <211> 182
      <212> PRT
      <213> Homo sapiens


      <400> 1220
 Met Gln Val Leu Val Lys Phe Arg Phe Leu Val Cys Ser Trp Leu Ser
   1               5                  10                  15    
 Ser Cys Cys Ile Leu His Met Leu Gly Ser Val Cys Pro Gly Gly Leu
              20                  25                  30        
 Leu Gly Cys Ala Phe Cys Gly Ser Arg Glu Leu Leu Val Gly Ala Leu
          35                  40                  45            
 Leu Leu Trp Thr Lys Pro Ser Pro Gln Leu Ser Pro Val Pro Ala Ser
      50                  55                  60                
 Gln Arg Leu Ser Ser Leu Ser Leu Met Pro Pro Leu Pro Gln Pro Gln
  65                  70                  75                  80
 His Leu Thr Pro Thr Ser Ile Glu Thr Leu Leu Trp Asn Val Glu Arg
                  85                  90                  95    
 Pro Trp Arg Met Lys His His Ala Asp Thr Gly Ile Gly Gly Trp Asn
             100                 105                 110        
 Gly Gly Gly Lys Glu His Arg Tyr Arg Gly Ala Gly Tyr Val Gly Lys
         115                 120                 125            
 Asp Pro Ala Trp Lys Trp Ile His Gln Arg Gln Leu Pro Gln Leu Met
     130                 135                 140                
 Pro Gly Pro Leu Leu Arg Asp Arg Val Thr His Ser His Ser Val Arg
 145                 150                 155                 160
 Ile Glu Lys Asp Ile Gly Ser Leu Gly Ala Val Val Pro Ala Tyr Val
                 165                 170                 175    
 Cys Lys Glu His Asn Cys
             180        



      <210> 1221
      <211> 350
      <212> PRT
      <213> Homo sapiens


      <400> 1221
 Met Ser Ile Ala Val Thr Thr Met Val Ala Ala Ala Ala Cys Lys Pro
   1               5                  10                  15    
 Trp Val Arg Val Pro Ser Ala Arg Gln Cys Arg Arg Ser Leu Glu Ala
              20                  25                  30        
 Pro His Glu Leu Ser Asp Trp Arg Ser Pro Phe Thr Leu Gly Leu Ser
          35                  40                  45            
 Asp Leu Val Cys Lys Met Trp Asp Gly Thr Thr Pro Lys Ala Ala Gly
      50                  55                  60                
 Lys Asp Leu Ser Phe Leu His Gln Gln Leu Thr Pro Val Gln Ala His
  65                  70                  75                  80
 Pro Leu Leu Glu Thr Leu Pro Gln Leu Pro Ser Gln Arg Pro Ser Glu
                  85                  90                  95    
 Pro Glu Leu Gly Ile Ser Lys Asp Arg Arg Pro Cys Thr Asp Leu Leu
             100                 105                 110        
 Ser Val Leu Arg Trp Lys Gln His Ile Val Trp Glu Thr Gly Cys Gln
         115                 120                 125            
 Thr Glu Lys His Phe Arg Gly Arg Asp Val Ser Thr Glu Gly Asp Thr
     130                 135                 140                
 Tyr Ala Cys Leu Asp Val Ile Leu Asn Val Ala Cys Leu Asp His Gly
 145                 150                 155                 160
 Lys Ser Glu His Ser Pro Lys Ser Pro Ser Thr Gln Ser Glu Glu Gln
                 165                 170                 175    
 Thr Leu Arg Gly Arg Gly Gln Ala Val Ala Asp Trp Pro Pro Gly Ala
             180                 185                 190        
 Gly Ala Cys Pro Gly Pro Ser Ala Arg Leu Cys Arg Gly Thr Met Gly
         195                 200                 205            
 Val Pro Ser Ala Ser Glu His Leu Lys Arg Ala Ala Leu Gly Gly Lys
     210                 215                 220                
 Arg Arg Cys Gly Glu Ala His Gly Leu Leu Arg Arg His Leu Ala Gln
 225                 230                 235                 240
 Asp Ser Ala Ala Ser Leu Gln Pro Glu Ala Trp Gly Glu Glu Gly Ala
                 245                 250                 255    
 Glu Ile Gly Pro Cys Gln Ala Asn Ser Ser Glu Asn Gly Gln Cys Pro
             260                 265                 270        
 Ala Pro Arg Gln Gly Arg Glu Gly Arg Pro Phe Arg Gln Leu Trp Ala
         275                 280                 285            
 Gly Ser Gly Cys Gly Pro Thr Gly Met Leu Gly Cys Gly Pro Gln Ala
     290                 295                 300                
 Tyr His Leu Leu Arg Pro Glu Ala Thr Pro Val Ala Ser Asn Gln Lys
 305                 310                 315                 320
 Ala Lys Gly Gln Asp Asp Gly Gly Arg Pro Asp Thr Pro Lys Gly Ser
                 325                 330                 335    
 Thr Cys Leu Ser Pro Asp Thr Leu Ser His Arg Trp Gly Asn
             340                 345                 350



      <210> 1222
      <211> 426
      <212> PRT
      <213> Homo sapiens


      <400> 1222
 Met Ala Ala Gly Pro Ile Arg Val Val Leu Val Leu Leu Gly Val Leu
   1               5                  10                  15    
 Ser Val Cys Ala Ala Ser Gly His Gly Leu Gly Ala His Arg Val Cys
              20                  25                  30        
 Arg Ala Gly Ala Cys Val Ala Ser Arg Asn Arg Arg Ala Leu Arg Asp
          35                  40                  45            
 Ser Arg Thr Arg Ala Leu Leu Phe Tyr Gly Thr Asp Phe Arg Ala Ser
      50                  55                  60                
 Ala Ala Pro Leu Pro Arg Leu Ala His Gln Ser Trp Ala Leu Leu His
  65                  70                  75                  80
 Glu Glu Ser Pro Leu Asn Asn Phe Leu Leu Ser His Gly Pro Gly Ile
                  85                  90                  95    
 Arg Leu Phe Asn Leu Thr Ser Thr Phe Ser Arg His Ser Asp Tyr Pro
             100                 105                 110        
 Leu Ser Leu Gln Trp Leu Pro Gly Thr Ala Tyr Leu Arg Arg Pro Val
         115                 120                 125            
 Pro Pro Pro Met Glu Arg Ala Glu Trp Arg Arg Arg Gly Tyr Ala Pro
     130                 135                 140                
 Leu Leu Tyr Leu Gln Ser His Cys Asp Val Pro Ala Asp Arg Asp Arg
 145                 150                 155                 160
 Tyr Val Arg Glu Leu Met Arg His Ile Pro Val Asp Ser Tyr Gly Lys
                 165                 170                 175    
 Cys Leu Gln Asn Arg Glu Leu Pro Thr Ala Arg Leu Gln Asp Thr Ala
             180                 185                 190        
 Thr Ala Thr Thr Glu Asp Pro Glu Leu Leu Ala Phe Leu Ser Arg Tyr
         195                 200                 205            
 Lys Phe His Leu Ala Leu Glu Asn Ala Ile Cys Asn Asp Tyr Met Thr
     210                 215                 220                
 Glu Lys Leu Trp Arg Pro Met His Leu Gly Ala Val Pro Val Tyr Arg
 225                 230                 235                 240
 Gly Ser Pro Ser Val Arg Asp Trp Met Pro Asn Asn His Ser Val Ile
                 245                 250                 255    
 Leu Ile Asp Asp Phe Glu Ser Pro Gln Lys Leu Ala Glu Phe Ile Asp
             260                 265                 270        
 Phe Leu Asp Lys Asn Asp Glu Glu Tyr Met Lys Tyr Leu Ala Tyr Lys
         275                 280                 285            
 Gln Pro Gly Gly Ile Thr Asn Gln Phe Leu Leu Asp Ser Leu Lys His
     290                 295                 300                
 Arg Glu Trp Gly Val Asn Asp Pro Leu Leu Pro Asn Tyr Leu Asn Gly
 305                 310                 315                 320
 Phe Glu Cys Phe Val Cys Asp Tyr Glu Leu Ala Arg Leu Asp Ala Glu
                 325                 330                 335    
 Lys Ala His Ala Ala Ser Pro Gly Asp Ser Pro Val Phe Glu Pro His
             340                 345                 350        
 Ile Ala Gln Pro Ser His Met Asp Cys Pro Val Pro Thr Pro Gly Phe
         355                 360                 365            
 Gly Asn Val Glu Glu Ile Pro Glu Asn Asp Ser Trp Lys Glu Met Trp
     370                 375                 380                
 Leu Gln Asp Tyr Trp Gln Gly Leu Asp Gln Gly Glu Ala Leu Thr Ala
 385                 390                 395                 400
 Met Ile His Asn Asn Glu Thr Glu Gln Thr Lys Phe Trp Asp Tyr Leu
                 405                 410                 415    
 His Glu Ile Phe Met Lys Arg Gln His Leu
             420                 425    



      <210> 1223
      <211> 270
      <212> PRT
      <213> Homo sapiens


      <400> 1223
 Met Arg Pro Ala Ala Leu Arg Gly Ala Leu Leu Gly Cys Leu Cys Leu
   1               5                  10                  15    
 Ala Leu Leu Cys Leu Gly Gly Ala Asp Lys Arg Leu Arg Pro Trp Leu
              20                  25                  30        
 Leu Cys Ser Phe Tyr Gly Ser Gly Ile Leu Arg Leu Asn Phe His Pro
          35                  40                  45            
 Arg Leu Glu Pro Ile Lys Val Lys Tyr Pro Ser Gly Lys Arg Gln Gln
      50                  55                  60                
 Leu Pro Arg Ala Leu Ala Trp Gln Gly Gly Asp Gly Ala Arg Ala Ala
  65                  70                  75                  80
 Ile Leu Gln Pro Pro Gly Ser Leu Leu Arg Pro Ala Gln Ala Pro Arg
                  85                  90                  95    
 Ser Arg Pro Pro Leu Gly Ala Gly Ser Val Leu Ser Ile Ala Ala Thr
             100                 105                 110        
 Arg Arg Pro Leu Arg Pro Leu Ala Ser Asp Ile Pro Ser Gly Arg Pro
         115                 120                 125            
 Pro Val Pro Val Arg Ala Ser Val Tyr Phe Leu Ser Tyr Tyr Gln Tyr
     130                 135                 140                
 Ser Thr Ser Arg Lys Gly Lys Phe Lys Asn Ala Asn Arg Thr Val Ala
 145                 150                 155                 160
 Gly Thr Met Glu Lys Asp Arg Gly Gly Ala Tyr Gly Asn Arg Val Leu
                 165                 170                 175    
 Pro Ile Ala Gln Leu Val Ile Val Ser Thr Leu Ala Cys Ala Glu Ala
             180                 185                 190        
 Val Arg Cys Ser Ala Leu Thr Asn Glu Gly Leu Val Gln Arg Glu Asp
         195                 200                 205            
 Ser Ala Leu Gly Ser Glu Arg Met Gly Glu Arg Gly Pro Gly Ala Leu
     210                 215                 220                
 Gln Phe Gln Leu Val Leu Met Ala Gly Trp Cys Ser Ser Val Glu Leu
 225                 230                 235                 240
 Ser Arg Val Cys Cys Met Ala Ala Gly Ala Asp Gly Trp Leu Val Phe
                 245                 250                 255    
 Phe Arg Gly Ala Leu Pro Cys Leu Leu His Gly Ser Arg Cys
             260                 265                 270



      <210> 1224
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 1224
 Met Leu Tyr Ala Leu Asn Ile Leu Arg Thr Val Leu Gly Arg Ala Arg
   1               5                  10                  15    
 Thr Leu Ser Leu Asn His Arg Cys Arg Leu Leu Leu Leu Ser Leu Leu
              20                  25                  30        
 Val Leu His Cys Val Arg Ser Val Arg Ser Trp Tyr Leu Phe Cys Glu
          35                  40                  45            
 Ala Ala Ala Glu Lys Thr Leu Ala Phe Ala Met Ala Glu Glu Lys Pro
      50                  55                  60                
 Lys Ala Leu Ser Met Gly Gln Ile Arg Phe Arg Phe Asp Ser Gln Pro
  65                  70                  75                  80
 Ile Asn Glu Thr Asp Thr Pro Ala Gln Val Glu Met Glu Asp Ile Asp
                  85                  90                  95    
 Ile Ile Asp Val Phe His Gln Gln Ile Gly Gly Val Tyr
             100                 105                



      <210> 1225
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1225
 Met Leu Lys Gly Leu Val Ala Leu Lys Pro Val Phe Leu Trp Met His
   1               5                  10                  15    
 Ile Lys Cys Ser Cys Gly Ala Leu Ala Leu Glu Pro Gln Asp Leu Ala
              20                  25                  30        
 Gln Ser Gln Ile Lys Ala Pro Leu Thr Asn Leu Thr Gly Leu Ser Leu
          35                  40                  45            
 Arg Pro Asp Asp Met Gln Gln Val Trp Arg Leu Leu His Lys Pro Ser
      50                  55                  60                
 His Pro Ser Val His Pro Val Pro His Pro Leu Leu Arg Leu Leu Cys
  65                  70                  75                  80
 Pro Asn Met Gln Val Pro Asp Ala Ser Ser Lys Ala Ala Ser His Pro
                  85                  90                  95    
 Thr Phe Ser Leu Ala Asn His Ile His Ser Gly Phe Glu Cys Tyr Leu
             100                 105                 110        
 Ser Thr Asn Pro Asn Tyr Pro Gln Asp Ser Val Cys Tyr Leu Met His
         115                 120                 125            
 Cys Asp Lys Ser Leu Leu Leu Lys Pro Ala Ser Met
     130                 135                 140



      <210> 1226
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1226
 Met Asp Thr Gly Phe Cys Leu Gln Val Thr Leu Leu Pro Leu Cys Leu
   1               5                  10                  15    
 Phe Arg Ala Gly Ser Gln Gln Arg Gly Glu Glu Thr Ala Pro His Val
              20                  25                  30        
 Lys Asp Lys Pro Tyr Asn Leu Trp Ile Lys Gln Arg Gln Glu Phe Trp
          35                  40                  45            
 Arg Tyr Ser Ala Pro Gly Thr Val Pro Thr Thr Ser Ala Ile Pro Gly
      50                  55                  60                
 Glu Thr Glu Trp Gly Arg Leu Pro Gln Trp Ser Thr Ala Trp Ser Glu
  65                  70                  75                  80
 Thr Ala Gln His Gly Trp Pro Ala Ala Arg Gln Ser Arg Ile Thr Val
                  85                  90                  95    
 Leu His Gln Gln Pro Gln Cys Asp Pro Gly Pro Glu Val Thr Ser Glu
             100                 105                 110        
 Gln Leu Pro Gly Val Ile Asn Trp Ile Arg Asn Cys Lys Cys Leu Cys
         115                 120                 125            
 Gly Gln Leu Ile Ser Thr Met Gly Ser Pro Lys Ser Gln Leu Leu Ser
     130                 135                 140                
 Gln Arg Gln
 145        



      <210> 1227
      <211> 254
      <212> PRT
      <213> Homo sapiens


      <400> 1227
 Met Ala Cys Leu Ile Ala Ser Pro Thr Leu Pro Leu Val Leu Ser Ser
   1               5                  10                  15    
 Leu Met Gly Val Leu His Ile Pro Pro Met Leu Phe Leu Arg Lys Leu
              20                  25                  30        
 Pro Glu Val Ile Leu Tyr Pro Lys Ile Leu Thr Ala Tyr Glu Ile His
          35                  40                  45            
 Lys Leu Ile Gln Pro Arg Lys Glu Ala Lys Gly Ile Ser Arg Leu Arg
      50                  55                  60                
 Lys Gly Lys Gly Lys Ser Lys Glu Thr Ser Thr Asn Trp Arg Arg Val
  65                  70                  75                  80
 Thr Gly Phe Gly Arg Ser Thr Gly Val Gly Ser Ser Val Gly Cys Leu
                  85                  90                  95    
 Leu Leu Asn Gly Ser Tyr Leu Gly Trp Asn Trp Ala Gly Glu Ala Ser
             100                 105                 110        
 Gly Thr Lys Glu Asp Lys Pro Gln Gly Ala Glu Gly Ala Val Ser Gly
         115                 120                 125            
 Leu Gly Gln Pro Arg Lys Gly Leu Pro Gln Cys Ser Gly Gly Leu Lys
     130                 135                 140                
 Gly Ser Ser Ser Thr Ala Thr Val Gly Ser Lys Ala Glu Glu Ala Pro
 145                 150                 155                 160
 Arg Val Ser Gln Gly Cys Glu Gly Cys Gln His Ala Val Thr Ser Gln
                 165                 170                 175    
 Leu His Leu Leu Lys Ser Lys Lys Thr Leu Glu Ala Val Leu Thr Ser
             180                 185                 190        
 Phe Leu His Gln Cys Gly Arg Lys Ser Phe Lys Thr Val Pro Met Thr
         195                 200                 205            
 Phe Ala Phe Arg Tyr Trp Gly Lys Arg Arg Arg Leu Ser Gly Thr Gln
     210                 215                 220                
 Thr Arg Arg Leu Asn Val Glu Lys Leu Phe Gln Gln His Ile Leu His
 225                 230                 235                 240
 Pro Arg Pro Phe Leu Glu Ile Pro Asn Pro Ser Met Pro Leu
                 245                 250                



      <210> 1228
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1228
 Met Gly Thr Pro Pro Glu Phe Leu Phe Pro Leu Gly Gln Pro Ile Gly
   1               5                  10                  15    
 Leu Cys Trp Ser Leu Leu Ala Arg Met Leu His Ser Asn Gly Phe Phe
              20                  25                  30        
 Arg Leu Leu Gly Asp Asp Ser Ile Ser Val Ala Arg Arg Cys Lys Pro
          35                  40                  45            
 Thr Ser Phe Phe Gln Ser Leu Glu Leu Leu Met Leu Ser Arg Ile Val
      50                  55                  60                
 Asp Leu
  65    



      <210> 1229
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 1229
 Met Gln Leu Arg Met Met Cys Ala Ser Leu Phe Ala Ile Thr Ser Gly
   1               5                  10                  15    
 Ser Gln His Asp Leu Arg Cys Ser Phe Thr Val Cys His Pro Phe Ser
              20                  25                  30        
 Met Ala Val Tyr Phe Val Tyr Gln Ile Lys Arg Asn Gly Met Thr Ala
          35                  40                  45            
 Glu Ala His Ser Val His Leu Trp Thr His Asn Ser Thr Leu Leu Gly
      50                  55                  60                
 Glu Leu Leu Tyr His Pro Gly Ser Lys Asp His Leu Cys Lys Ser Glu
  65                  70                  75                  80
 Gly Lys Leu Cys Arg Ile Lys Ala Glu Val Ser Arg Asn Phe Gln Tyr
                  85                  90                  95    
 Tyr Gly Ala Tyr Ala Ser Leu Leu Arg Leu Met Glu Val Phe Arg Lys
             100                 105                 110        
 Glu Lys Glu Ser Gln Thr Ala Tyr Thr Glu Cys Glu Glu Gly Glu Glu
         115                 120                 125            
 Asn Thr Gln Gly Phe
     130            



      <210> 1230
      <211> 193
      <212> PRT
      <213> Homo sapiens


      <400> 1230
 Met Gln Lys Lys Pro Glu Ala His Leu Pro Gln Ile Ile His Leu Leu
   1               5                  10                  15    
 Gly Leu Leu Leu Ser Val Lys Leu Leu Pro Leu Ala Ser Leu Pro Trp
              20                  25                  30        
 Ile Lys Asp Gln Leu Lys Tyr Gly Ser Val Asn Ser Ser Leu Trp Arg
          35                  40                  45            
 Glu Gly Met Lys Arg Asn Leu Gly Gln Glu Glu His Glu Pro Ala Ser
      50                  55                  60                
 Ile Ile His Phe Tyr Arg Lys Ala Ser Gly Tyr Ala Gln Ala Cys Gly
  65                  70                  75                  80
 Gln Met Ser Met Phe Ala Val Arg Pro Phe Gln His Lys His Met Val
                  85                  90                  95    
 Trp Ser Val Ser Pro Ala Ser Pro Ser Val Leu Gly Ala Pro Ser His
             100                 105                 110        
 Thr Asn Ala Pro Val Gly Pro Cys Ser Leu His Pro Gln Ser Glu Gly
         115                 120                 125            
 Asn Trp Arg Gly Ala Val Leu Tyr Gln Asn Ile Ser Ser Ser Trp Val
     130                 135                 140                
 Ser Ser Leu Leu Ala Phe Gly Leu Asp Leu Thr Pro Ser Ala Leu Met
 145                 150                 155                 160
 Val Leu Ser Pro Leu Asp Ser Asp Cys Asn Trp Thr Leu Ala Leu Leu
                 165                 170                 175    
 Gly Leu Gln Leu Ala Asp Cys Arg Ser Gly Leu Phe Gln Pro Val Ile
             180                 185                 190        
 Leu
    



      <210> 1231
      <211> 189
      <212> PRT
      <213> Homo sapiens


      <400> 1231
 Met Thr Val Gly Val Gly Phe His Pro Leu Ile Ala Gln Trp Thr Val
   1               5                  10                  15    
 Cys Cys Gln Met Glu Gln Pro Val Arg Ser Thr Arg Met Pro Tyr Gly
              20                  25                  30        
 Gly Ser Lys Ile Asp Pro Gly Gly Lys Val Ala Gly Thr Pro Gly Pro
          35                  40                  45            
 His Val Arg Arg Ala Leu Ser Leu Cys Leu Glu Asp Glu Arg Arg Ala
      50                  55                  60                
 Asn Cys Thr Leu Lys Glu Arg Pro Ser Thr Cys Asp Asn Pro Gly Pro
  65                  70                  75                  80
 Cys Val Thr Ala Asp Glu His Lys Cys Ser Gln Arg Ser Thr Val Gln
                  85                  90                  95    
 Pro Leu Thr Val Arg Gly Glu Ala Ile Ser Cys Arg Gly Pro His Ser
             100                 105                 110        
 Glu Val Arg Thr Glu Ser Glu Ala Pro Ser His Gly Lys Cys Arg His
         115                 120                 125            
 Leu Thr Asp Leu Ile Leu Ser Lys Gln Glu Gly Ala Gly Leu Ser His
     130                 135                 140                
 Ser Leu Lys Leu Lys Met Gly Phe Cys Ala Ile Val Ile Ile Pro Pro
 145                 150                 155                 160
 Leu Glu Thr Gly Glu Phe Arg Thr Pro Ile Lys Arg Leu Thr Gln Gly
                 165                 170                 175    
 His Tyr Gln Pro Tyr Ile Tyr Asn Ser Arg Thr Arg Val
             180                 185                



      <210> 1232
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1232
 Met Ala Phe Asn Leu Ala Phe Cys Ala Pro Gly Ala Trp Ala Ala His
   1               5                  10                  15    
 Leu Gly Leu Ala Asp Gly Thr Val Phe Gln Trp Leu Lys Glu Gln Leu
              20                  25                  30        
 Ser Gln Ala Glu Ala Gly Gly Ser Asn Pro Ser Ala Val Leu His Gly
          35                  40                  45            
 His Val Arg Met Arg Thr Gly Arg Glu Leu Leu Arg His Arg Asp Phe
      50                  55                  60                
 Ser Ser Leu Leu Leu Gln Arg Leu Ile Ser Ala Ile Gly Trp
  65                  70                  75            



      <210> 1233
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1233
 Met Gly Phe Ser Ser Pro Gly Pro Ser Arg Gly Thr Ser Ser Leu Leu
   1               5                  10                  15    
 Leu Ser Ala Trp Leu Ile Ala Leu Pro Pro Ser Ser Val Ala Arg Gly
              20                  25                  30        
 Arg Ser Glu Gly Val Ala Val Lys Leu Pro Phe Leu Leu Met Ala Leu
          35                  40                  45            
 Ile Ala Val Pro Phe Ala Pro Ala Asp Arg Ala Pro Ala Ala Pro Ala
      50                  55                  60                
 Ala Pro Ala Ala Asp Gln Gly Ser Trp Cys Leu Cys Gln Leu Asn Gly
  65                  70                  75                  80
 Ala Ala Asp Leu Glu Val Ser Glu Gly Pro His Pro Ala Arg Gly Arg
                  85                  90                  95    
 Gly Pro Arg Val Arg Asp Ser Arg Asp Trp Arg Arg Gly Arg Val Phe
             100                 105                 110        
 Ala Gly Gln Lys Arg Asp Ser Glu Ser Pro Gly Thr Asp Pro Gly Ala
         115                 120                 125            
 Val Leu Gly Gln Gly Trp Leu Cys
     130                 135    



      <210> 1234
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1234
 Met Ala Ala Arg Trp Arg Phe Trp Cys Val Ser Val Thr Met Val Val
   1               5                  10                  15    
 Ala Leu Leu Ile Val Cys Asp Val Pro Ser Ala Ser Ala Gln Arg Lys
              20                  25                  30        
 Lys Glu Val Arg Thr Arg Phe Pro Ala Ala Trp Ala Phe Pro Asn Asp
          35                  40                  45            
 Trp Gly Leu Arg Gly Ser Val Arg Leu Phe Pro Ala Pro Phe Pro Cys
      50                  55                  60                
 Arg Phe Tyr Ala Phe Gly Gly Phe Asn Tyr Ala Val Phe Gly Val Val
  65                  70                  75                  80
 Glu Phe Val Arg Glu Gly Thr Val Thr Leu Cys Leu Leu Gly Met
                  85                  90                  95



      <210> 1235
      <211> 221
      <212> PRT
      <213> Homo sapiens


      <400> 1235
 Met Ala Asp Asn Leu Tyr Val Tyr Ala Val Leu Val Cys Cys Val Gly
   1               5                  10                  15    
 Ile Leu Ser Ile Leu Leu Phe Met Leu Val Ile Val Trp Gln Ser Val
              20                  25                  30        
 Phe Asn Lys Arg Lys Ser Arg Gly Gln Asn Ala Leu Arg Met Gln Ser
          35                  40                  45            
 Arg Glu Gln Gly Leu Ser Lys Arg Leu Arg Asp Leu Tyr Thr Gly Ser
      50                  55                  60                
 Thr Gln Lys Leu Leu Glu Ala Ile Val Gly Phe Phe Phe Ser Phe Leu
  65                  70                  75                  80
 Phe Cys Asn Lys Ser Ala Phe Gly Phe Thr Gly Asn Phe Phe Phe Tyr
                  85                  90                  95    
 Ser Ser Gly Glu Thr Val Thr Ser Val Thr Ser Leu Ala Pro Leu Gln
             100                 105                 110        
 Pro Lys Lys Gly Lys Arg Gln Lys Glu Lys Pro Asp Ile Pro Pro Ala
         115                 120                 125            
 Val Pro Ala Lys Ala Pro Ile Ala Pro Thr Phe His Lys Pro Lys Leu
     130                 135                 140                
 Leu Lys Pro Gln Arg Lys Val Thr Leu Val His Met His Ser Pro Leu
 145                 150                 155                 160
 Leu Leu Arg Gly Val Met Tyr Val Ser Trp Arg Glu Glu Arg Met Leu
                 165                 170                 175    
 Arg Leu Gln Lys Gly Trp Ala Cys Gly Lys Gln Lys Pro Phe Ala Phe
             180                 185                 190        
 Met Ala Ser Ser Ser Leu Glu Arg Ala Gly Ile Ser Ala Phe Gly Lys
         195                 200                 205            
 Leu Asp Val Ile Lys Ile Ile Pro Leu Pro His Trp Lys
     210                 215                 220    



      <210> 1236
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1236
 Met Arg Trp Glu Pro Glu His Val Cys Pro Ala Cys Lys Ala Leu His
   1               5                  10                  15    
 Asn Leu Ala Leu Leu Ile Pro Leu Pro Val Thr Leu Phe Ala Pro Ala
              20                  25                  30        
 Ala Ser Leu Ala Val His Ser Phe Val Leu Pro Lys Asp Asp Val Ala
          35                  40                  45            
 Pro Tyr Phe Lys Thr Glu Pro Gly Leu Pro Gln Ile His Leu Glu Gly
      50                  55                  60                
 Asn Arg Leu Val Leu Thr Cys Leu Ala Glu Gly Ser Trp Pro Leu Glu
  65                  70                  75                  80
 Phe Lys Trp Met Arg Asp Asp Ser Glu Leu Thr Thr Tyr Ser Ser Glu
                  85                  90                  95    
 Tyr Lys
        



      <210> 1237
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1237
 Met Arg Lys Phe Thr Lys Ser Leu Gly Ser Val Ser Met Asn Ala Phe
   1               5                  10                  15    
 Ser Phe Leu Leu Asn Phe Val Leu Leu Leu Pro Lys Phe Ser Gly Ala
              20                  25                  30        
 Arg Arg Glu Gln Gly Ser Cys Arg Leu Gln Val Ala Pro Pro Ile Ser
          35                  40                  45            
 Asp Arg Ile Arg Tyr Ser Thr Lys Trp Arg Pro Asn Arg Asp Phe Lys
      50                  55                  60                
 Asp Met Lys Lys Lys Val Cys Trp Ser Arg Gly Thr Glu Ile Asp Lys
  65                  70                  75                  80
 Val Asn Gly Asp Pro Arg Glu Lys Leu Thr Gln Leu Gln Gln Leu Val
                  85                  90                  95    
 Lys Glu Gln Trp Asp Ala Gly Leu Arg Glu Glu Ser Ala Pro Gly Ile
             100                 105                 110        
 Leu Gln Cys Leu Leu Leu Gln Lys Ser Pro Glu Asp Gly Asp Cys Tyr
         115                 120                 125            
 Met Ile
     130



      <210> 1238
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 1238
 Met Thr Leu Gly Val Ser Ala Val Pro Ala Ala Arg Leu Leu Leu Phe
   1               5                  10                  15    
 Trp Gly Arg Gly Leu Ala Arg Ala Gly Val Gly Leu Gly Glu Ala Arg
              20                  25                  30        
 Val Glu Ala Gly Ala Leu Leu Arg Ala Arg Arg Ile Phe Thr Phe Pro
          35                  40                  45            
 Leu Ile Ser Leu Thr Glu Ala Gly Cys Arg Ala Phe Ala Ser Ser Asp
      50                  55                  60                
 Trp Trp Asn Cys Leu His Pro Gly Pro Gly Leu Pro Gly Gly Gly Gly
  65                  70                  75                  80
 Gly Gly Gly Gly Ala Gly Thr Arg Asp Gly Asp Leu Ala Ser Ser Leu
                  85                  90                  95    
 Leu Ser Arg Pro Gln Tyr Pro Ser Cys Leu Leu Pro Gly Asp Pro Leu
             100                 105                 110        
 Gly Ala Leu Pro Met Arg Ala Arg Glu Lys Gly Ala Ser Gly Thr Glu
         115                 120                 125            
 Arg Pro Arg Leu Gly Glu Gly Arg Arg Val Gly Gly Ala Arg Leu Leu
     130                 135                 140                
 Arg Thr Lys Ser Gly Phe Ala Arg Asn Pro Arg Arg Ser Leu Pro Ala
 145                 150                 155                 160
 Arg Arg Ser Cys Gly Met Arg Trp Gly Cys Gly Asp Ala Cys Thr Ile
                 165                 170                 175    
 Ser Ala Gln Ala Ser Arg Glu Trp
             180                



      <210> 1239
      <211> 314
      <212> PRT
      <213> Homo sapiens


      <400> 1239
 Met Ala Ile Asn Met Arg Met Gln Thr Leu Arg Ile Leu Thr Ala Leu
   1               5                  10                  15    
 Leu Cys Pro Cys Glu Ser Gly Leu Lys Asn Val Ser Ser Asp Val His
              20                  25                  30        
 Arg Pro Ser Phe Glu Lys Gln Asp Ser Ser Pro Arg Ala Arg Pro Glu
          35                  40                  45            
 Gly Arg Gly Gly Lys Glu Pro Gly Ser Gly Ser Arg Arg Pro Leu Leu
      50                  55                  60                
 Leu Val Ala Glu Gln Gln Glu Ile Gln Lys Thr Gly Gly Leu Gly Gln
  65                  70                  75                  80
 Ala Pro Ala Leu Asp Ile Thr Arg Arg Ser Leu His Ser Thr Lys Leu
                  85                  90                  95    
 Pro Gln Leu Glu Asn Gly Ala Ala Gly Pro His Arg Gly Gly Gly Thr
             100                 105                 110        
 Lys Lys Met Asp Val Arg Ala Pro Ser Ala Gly Leu Gly Gly Gly Gly
         115                 120                 125            
 Gly Asn Arg Met Pro Ser Gln Asn Leu His Leu Ala Asn Ala Leu Ala
     130                 135                 140                
 Ala Ala Gly Asp Leu Pro Lys Val Thr Pro Ala Glu Ser Gln Gly Glu
 145                 150                 155                 160
 Asp Arg Lys Ala Val Asn Leu Ala Gly Lys Ser Leu Pro Tyr Leu Pro
                 165                 170                 175    
 Leu Ser Val His Leu His Cys Phe Val Pro Leu Gln Ser Ser Ile Phe
             180                 185                 190        
 His Ser Cys Gln Gly Lys Lys Leu Glu Gly Ser Leu Ser Asn Gly Ser
         195                 200                 205            
 Leu Arg Asp Arg Ser Leu Ser Asn Gly Ser Leu Arg Asp Arg Ser Leu
     210                 215                 220                
 Ser Ser Gly Ser Leu Arg Asp Arg Ser Leu Ser Ser Gly Ser Leu Gly
 225                 230                 235                 240
 Asp Arg Ser Leu Cys Ala Leu Ser Glu Glu Ala Gln Ala Ala Ala Leu
                 245                 250                 255    
 Gln Asp Glu Ala Pro Lys Ala Ser Ser Glu Glu Trp Gln Glu Ala His
             260                 265                 270        
 Pro Thr Val His Leu Thr Gln Leu Leu Thr Gly Pro Lys Phe Leu Leu
         275                 280                 285            
 Pro Thr Leu Cys Leu Gln Glu Trp Ile Ser Val Leu Met Gln Gln Glu
     290                 295                 300                
 Gly Phe Gly Ser Ala Glu Thr Tyr Arg Val
 305                 310                



      <210> 1240
      <211> 346
      <212> PRT
      <213> Homo sapiens


      <400> 1240
 Met Thr Trp Arg Ala Ala Ala Ser Thr Cys Ala Ala Leu Leu Ile Leu
   1               5                  10                  15    
 Leu Trp Ala Leu Thr Thr Glu Gly Asp Leu Lys Val Glu Met Met Ala
              20                  25                  30        
 Gly Gly Thr Gln Ile Thr Pro Leu Asn Asp Asn Val Thr Ile Phe Cys
          35                  40                  45            
 Asn Ile Phe Tyr Ser Gln Pro Leu Asn Ile Thr Ser Met Gly Ile Thr
      50                  55                  60                
 Trp Phe Trp Lys Ser Leu Thr Phe Asp Lys Glu Val Lys Val Phe Glu
  65                  70                  75                  80
 Phe Phe Gly Asp His Gln Glu Ala Phe Arg Pro Gly Ala Ile Val Ser
                  85                  90                  95    
 Pro Trp Arg Leu Lys Ser Gly Asp Ala Ser Leu Arg Leu Pro Gly Ile
             100                 105                 110        
 Gln Leu Glu Glu Ala Gly Glu Tyr Arg Cys Glu Val Val Val Thr Pro
         115                 120                 125            
 Leu Lys Ala Gln Gly Thr Val Gln Leu Glu Val Val Ala Ser Pro Ala
     130                 135                 140                
 Ser Arg Leu Leu Leu Asp Gln Val Gly Met Lys Glu Asn Glu Asp Lys
 145                 150                 155                 160
 Tyr Met Cys Glu Ser Ser Gly Phe Tyr Pro Glu Ala Ile Asn Ile Thr
                 165                 170                 175    
 Trp Glu Lys Gln Thr Gln Lys Phe Pro His Pro Ile Glu Ile Ser Glu
             180                 185                 190        
 Asp Val Ile Thr Gly Pro Thr Ile Lys Asn Met Asp Gly Thr Phe Asn
         195                 200                 205            
 Val Thr Ser Cys Leu Lys Leu Asn Ser Ser Gln Glu Asp Pro Gly Thr
     210                 215                 220                
 Val Tyr Gln Cys Val Val Arg His Ala Ser Leu His Thr Pro Leu Arg
 225                 230                 235                 240
 Ser Asn Phe Thr Leu Thr Ala Ala Arg His Ser Leu Ser Gly Met Phe
                 245                 250                 255    
 Ile Pro His Ile Asn Asn Ser Ile Glu Gly Gln Leu Ile Leu Lys Asp
             260                 265                 270        
 Lys Phe Ile Thr Gln Thr Ala Pro Asp Ile Arg Arg Lys Leu Glu Lys
         275                 280                 285            
 Gln Ala Met Gly Leu Asp Ser Thr Leu Gln Asn Leu Leu Lys Val Ala
     290                 295                 300                
 Thr Ser Val Phe Tyr Asn Arg Asp Gln Glu Glu Ala Gln Gly Lys Glu
 305                 310                 315                 320
 Arg Lys His Lys Lys Lys Ala Glu Thr Leu Val Ala Thr Leu Tyr Lys
                 325                 330                 335    
 Thr Gln Tyr Pro Gln Glu Pro Ser Ser Ser
             340                 345    



      <210> 1241
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 1241
 Met Met Ile Leu Met Met Met Val Leu Ser Pro Gln Leu Pro Ser Pro
   1               5                  10                  15    
 Lys Gly Ala Ser Arg Glu Ala Ile Gly Val Gly Arg Ser Asp Pro Leu
              20                  25                  30        
 Ser Arg His Leu Glu Thr Arg Phe Pro Gly Lys Ala Ala Lys Ala Ser
          35                  40                  45            
 Tyr Phe Phe Leu Gln Leu Ser Gln Gln Met Leu Lys Leu Leu Pro Gln
      50                  55                  60                
 Ala Asn Thr Leu Arg Gly Gly Ile His Ser Ala Ile Cys Phe Phe Leu
  65                  70                  75                  80
 Lys Val Glu Glu Glu Gln Lys Ser Pro Leu Ser Lys Arg Asn Met Gly
                  85                  90                  95    
 Ser Met Ala Ser Glu Gly Cys Ile Leu His Leu Asn Ala Val Trp Arg
             100                 105                 110        
 Glu Gly Met Cys Tyr Gly Leu Asn Cys Val Ser Arg Asn Ser Tyr Val
         115                 120                 125            
 Glu Gly Leu Ser Pro Asn Val Met Ala Leu Ala Gly Thr Lys Arg Ala
     130                 135                 140                
 Ala Ser Glu Gln Thr Thr Ser Leu His Thr Glu Gly Ile Thr Asp Arg
 145                 150                 155                 160
 Phe Arg Arg Gln Thr Gln Glu Ala Ala His Thr Pro Ser Ala Thr Ala
                 165                 170                 175    
 Ala Val Thr Pro Arg Ile Asp Ser Arg Ser Gln Asn Ile Leu Pro Val
             180                 185                 190        
 Ala Ser Ala Asn Asp Leu Pro Gln Gly Thr Ile Arg Glu Gln Thr Asn
         195                 200                 205            
 Pro Glu Lys Pro Thr
     210            



      <210> 1242
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1242
 Met His Arg Val Leu Arg Leu Cys Pro Leu Leu Gly His Pro Val Trp
   1               5                  10                  15    
 Ser Leu Ala Ala Leu Ala Phe Ala Leu Trp Ile Gln Gly Gly Lys Ser
              20                  25                  30        
 Glu Leu Gly Ser Cys Ser Pro Ser Ser Gly Ser Trp Asp Leu Gly Gln
          35                  40                  45            
 Ala Gly Lys Glu Leu Asn Cys Gly Gly Arg Gly Ala Pro Lys Trp Ile
      50                  55                  60                
 Ser Gly Thr Ser Ala Pro Asp Pro Gly His Pro Ala Arg Tyr Ser Ala
  65                  70                  75                  80





      <210> 1243
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 1243
 Met Ala Gly Pro Gly Ser Pro Arg Arg Ala Ser Arg Gly Ala Ser Ala
   1               5                  10                  15    
 Leu Leu Ala Ala Ala Leu Leu Tyr Ala Ala Leu Gly Asp Val Val Arg
              20                  25                  30        
 Ser Glu Gln Gln Ile Pro Leu Ser Val Cys Asn Ile Gln Ile Gln Ala
          35                  40                  45            
 Leu Gln Val Ile Phe Ile Glu Leu Leu Trp Gly Leu Ala Ala Tyr Ile
      50                  55                  60                
 His Val Tyr Leu Val Asn Glu Gln Val His Glu Trp Gly Gln Glu Tyr
  65                  70                  75                  80
 Gly Asn Glu
            



      <210> 1244
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1244
 Met Ser Gly Trp Leu Gly Leu Val Ser Ser Leu His Arg Leu Leu Val
   1               5                  10                  15    
 Ser Pro Cys Pro Gly Arg Thr Val Gly Leu Gln Arg Arg Lys Arg Leu
              20                  25                  30        
 Lys Ser Gly Ser Ser Arg Met Ser Phe Pro Val Thr Arg Arg Pro Arg
          35                  40                  45            
 Glu Gln Thr Pro His Pro Asp Ile Val Ala Ala Ile Pro Ser Gly Thr
      50                  55                  60                
 Asp Asp Phe Gln Gly His Arg Ser Lys Glu Lys Glu Asn Trp Lys Pro
  65                  70                  75                  80
 Met Cys Leu Asn Arg Phe Ile Leu Glu Glu Cys Ile Ala Ala Asp Asp
                  85                  90                  95    
 Phe Arg Ile Arg Gly Leu Glu Pro Asn Pro Gln Tyr Leu Gln Gly Lys
             100                 105                 110        
 Pro Thr Gln Val Ser Glu Ser Leu Arg Leu Leu Arg Asn Asp Thr Gln
         115                 120                 125            
 Asp Pro Asn Ile Lys Thr Arg Tyr Ile Met Asn Leu Ala Lys Thr Ile
     130                 135                 140                
 Gln Arg Ser Pro Asp Lys
 145                 150



      <210> 1245
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 1245
 Met Arg Leu His Trp Gln Leu Leu Gln Gly Leu Ala Arg Ala Trp Glu
   1               5                  10                  15    
 Leu Gly Ser Ala Cys Ala Ser Ala Val Met Thr Pro Leu Leu Arg Asn
              20                  25                  30        
 Phe Glu Pro Ser Phe Ser Pro Ser Pro Ile Glu Lys Pro Ser Ala Pro
          35                  40                  45            
 Ser Ser Gly Gln Ser Ser Gln Leu Gln Thr Gln Val Gln Pro Pro Ala
      50                  55                  60                
 Glu Arg Gly Ala Ala Ser Met Pro Gly Pro Ala Ser Leu Pro Leu Ser
  65                  70                  75                  80
 Thr Gly Pro Ser Gln Pro Leu Arg Cys Ser Pro Arg Val Leu Cys Ser
                  85                  90                  95    
 Arg Val Leu Ala Leu Arg Arg Arg Glu Pro Pro Gly Glu Thr Glu Ala
             100                 105                 110        
 Met Gly Pro Asp Ala Arg Ala Gly Asp Asp Ser Glu His Thr Val Ser
         115                 120                 125            
 Arg Glu Pro Pro Gly Glu Thr Glu Ala Met Gly Pro Asp Ala
     130                 135                 140        



      <210> 1246
      <211> 285
      <212> PRT
      <213> Homo sapiens


      <400> 1246
 Met Glu Ser Phe Leu Leu Leu Leu Ser Ala Thr Ser Tyr Phe Val Tyr
   1               5                  10                  15    
 Gly Val Gly Val Leu Ser Pro Leu Cys Phe Leu Asn Lys Leu Ala Phe
              20                  25                  30        
 Thr Leu His Cys Gly Leu Ala Leu Asn Ser Phe Leu Arg Glu Ile Gln
          35                  40                  45            
 Glu Pro Ser Leu Gly Val Trp Ile Gly Thr Pro Ala Leu Lys His Ile
      50                  55                  60                
 Pro Gly Asn His Arg Arg Asp Phe Ser Ala Glu Thr Leu Thr Gln Arg
  65                  70                  75                  80
 Leu Pro Leu Gly Ser Ser Pro Pro Gly His Ser His Pro Leu Thr Asn
                  85                  90                  95    
 His Gln Tyr Lys Ser Asn Ser Gln Tyr Lys Ala Lys Ala Pro Asn Pro
             100                 105                 110        
 Ile Ser Arg Val Ser Val Pro Phe Ser Gln Leu Leu Thr Gly Leu Lys
         115                 120                 125            
 Ser Leu Gln His Thr His Thr Pro His Asn His Tyr Ser Glu Val Gly
     130                 135                 140                
 Val Ser Val Gln Val Gln Thr His Ile Tyr Asp Tyr Leu Leu Phe Leu
 145                 150                 155                 160
 Thr Ile Ile Leu Asp Ile Asn Tyr Leu Ala Lys Lys Asn Gln Lys Ser
                 165                 170                 175    
 Ile Phe Phe Val Val Met Arg Leu Cys Leu Leu Arg Asn Ser Ser Ser
             180                 185                 190        
 Val Gln Lys Leu Ser Asn Met Val Leu Lys Ala Phe Glu Asn Leu Ile
         195                 200                 205            
 Ser Pro Ser Ala Val Thr Phe Leu Asn Val Ala Ile Ala Val Thr His
     210                 215                 220                
 Thr Leu Lys Thr Leu His Ser Ala Val Asp Ser Ile Val Leu Leu Leu
 225                 230                 235                 240
 Ser Trp Ser Ile Gly Lys Arg His Thr Ala Lys Val Arg Ala Ala Gly
                 245                 250                 255    
 Glu Leu Ile Ile Pro Gly Thr Pro Leu Leu Leu Ser Glu Tyr Pro Ser
             260                 265                 270        
 Asp Gln Ser Glu Arg Ser Ser Glu Arg Gly His Ala Ala
         275                 280                 285



      <210> 1247
      <211> 262
      <212> PRT
      <213> Homo sapiens


      <400> 1247
 Met Gly Arg Glu Arg Asp Pro Ser Gly Trp Thr Trp Leu Leu Arg Cys
   1               5                  10                  15    
 Ala Ala Ala Ala Cys Ala Leu Leu Leu Gly Ser Gln Arg Gln Glu Thr
              20                  25                  30        
 Gln Leu Leu Leu Ser Glu His Ser Asp Pro Asp Ile Glu His Arg Val
          35                  40                  45            
 Arg Gly Glu Pro Lys Arg Thr Thr Arg Trp Leu Gly Val Glu Cys Trp
      50                  55                  60                
 Arg Gln Gly Val Ile Asn Ile Glu Thr Lys Ala Gln Glu Gln Leu Gln
  65                  70                  75                  80
 Pro Lys Gly Lys Lys Val Ser Ser Leu Leu Thr Ala Leu Pro Gly Ser
                  85                  90                  95    
 Ile Asp Glu Leu Ser Leu Lys Arg Asp Val Lys Glu Ser Ile Ser Leu
             100                 105                 110        
 Pro Ala Val Pro Phe Gln Ile Glu Leu Leu Leu Ile Ser Lys Ile Asn
         115                 120                 125            
 Met Gln Thr Arg Leu Leu Gln Leu Pro Leu Lys Phe Ala Val Ala Ala
     130                 135                 140                
 Ala Ser Ser Arg Phe Asn Pro Arg Pro Pro Val Ile Gly Gln Leu Leu
 145                 150                 155                 160
 Arg Gly Lys Lys Ser Thr Pro Trp Gln Pro Asp Lys Pro Ile Lys Ser
                 165                 170                 175    
 Pro Ala Gly Val Thr Ala Ala Thr Leu Gln Ala Gly Val Gly Trp Ala
             180                 185                 190        
 Glu Glu Gln Ser Gly His Cys Ala Gln Val His Ser Leu Gly Val Asp
         195                 200                 205            
 Ser Ser Cys Trp Ser Pro Arg Ser Gly Tyr Thr Tyr Val His His Pro
     210                 215                 220                
 Val His Thr Pro Thr Leu Cys Ala Leu Val Gly Ser Gly Gly Glu Arg
 225                 230                 235                 240
 Gly Gly Gly Glu Gly Glu Lys His Ile Gly Leu Glu Glu Gln Glu Pro
                 245                 250                 255    
 Gln Lys Arg Val Leu Asn
             260        



      <210> 1248
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1248
 Met Pro Leu Pro Trp Val Ala Phe Cys Ser Val Asp Met Val Pro Thr
   1               5                  10                  15    
 Leu Lys Ala Cys Cys Ala Val Leu Val Leu Thr Ser Gly Phe Gly Arg
              20                  25                  30        
 Lys Glu Glu Met Asn Arg Asn Ile Met Glu Asp Gln Pro Ile Thr Gly
          35                  40                  45            
 Ile Leu Ala Cys Val Gln Ala Gln Cys Pro Val Leu Glu Leu Asp Val
      50                  55                  60                
 Cys Val Ala Ser Ser Pro Ala Ile Lys Tyr Cys Val Asp Leu Gly His
  65                  70                  75                  80
 Ser Asp Val Asp Pro Ile Leu Gln Gly Ser Pro Pro Pro Thr Glu Ala
                  85                  90                  95    
 Gln Asp Gly Gln Val Thr Phe
             100            



      <210> 1249
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1249
 Met Ser Leu Lys Thr Thr Cys Ala His Val Leu Val Arg Lys Ser Leu
   1               5                  10                  15    
 Leu Phe Ile Pro Thr Ala Lys Gly Pro Val Ile Asn Ala Pro Leu Pro
              20                  25                  30        
 Gln Arg Leu Arg Ser Asn Thr Ala Pro Ile Arg Thr Leu His Ala Pro
          35                  40                  45            
 Ser Val His Arg Pro Thr Gly Arg Glu Ser Met Pro Arg Thr Arg Leu
      50                  55                  60                
 Thr Arg Ala Arg Thr Ser Pro Asp Thr Thr Gly Ser Asp Lys Thr Pro
  65                  70                  75                  80
 His Pro Arg Pro Lys Thr Leu Pro Ile Gln Thr Arg Ser Cys Ala Asp
                  85                  90                  95    
 Ser Gly Lys Leu Ser Gly Lys Asp Arg Glu Ala Arg Arg Gly Pro Arg
             100                 105                 110        
 Ser Leu Pro Gly Ile Ala Ser Ser Asp Cys Gly Arg Arg Ser Met Arg
         115                 120                 125            
 Ser Gln Gly Cys Ala His Arg Ser Val Ser Asp Arg Ser Gly His Asn
     130                 135                 140                
 Gly Cys Gly Asn His Ser
 145                 150



      <210> 1250
      <211> 301
      <212> PRT
      <213> Homo sapiens


      <400> 1250
 Met Gly Trp Ala Arg Trp Leu Thr Pro Val Ile Pro Ala Leu Trp Glu
   1               5                  10                  15    
 Ala Glu Val Gly Gly Ser Pro Lys Ser Pro Tyr Ile Leu Asp Ser Tyr
              20                  25                  30        
 Glu Leu Thr Arg Ala Ser Thr Leu Thr Leu Ile Thr Thr Thr Pro Met
          35                  40                  45            
 Cys Leu Ser Ser Leu Arg Leu Pro Glu Thr Pro Val Asn His Leu Gly
      50                  55                  60                
 Leu Glu Ser Arg Ala Pro Glu His Leu Ala Val Leu Ala Arg Ser Asn
  65                  70                  75                  80
 Ala Pro Thr Ala Gly Gly Arg Arg Arg Arg Glu Asp Arg Arg Glu Asp
                  85                  90                  95    
 Val Arg Ser Arg Ala Arg Arg Gly Gly Phe Gly Cys Pro Pro Ser Ser
             100                 105                 110        
 Gly Ala Cys Arg Ser Asn Trp Val Trp Ile Cys Thr Val Lys Glu Gly
         115                 120                 125            
 Gly Arg Glu Gly Arg Gly Gly Arg Gly Arg Arg Val Gln Leu Ala Ala
     130                 135                 140                
 Val Ala Gly Thr Val Ala Pro Ala Ala Ala Pro Lys Asn Pro Pro Pro
 145                 150                 155                 160
 Arg Phe Arg Trp Ser Val Trp Ala Arg Asp Gly Val Lys Glu Arg Val
                 165                 170                 175    
 Pro Leu Gln Ala Gly Val Gly Gly Gly Gln Ala Val Gln Arg Arg Glu
             180                 185                 190        
 Thr Ala Arg Arg Ser Arg Gly Trp Leu Leu Arg Ile Trp Asp Ser Ile
         195                 200                 205            
 Gly Arg Asp Arg Ser Leu Gly Gly Asn Gly Phe Phe Thr Thr Ala Asp
     210                 215                 220                
 Gln Arg Phe Asp Phe Ala Val Leu Trp Leu Val Ala Phe Arg Ile Asn
 225                 230                 235                 240
 Ser Asp Lys Leu Gly Ser Ser Leu Asn Ala Val Pro Arg Ile Cys Ser
                 245                 250                 255    
 Ile Pro Ser Thr Pro Arg Tyr Val Ala Leu Arg Ser Ala Leu Gly Arg
             260                 265                 270        
 Arg Leu Gln Leu Gly Tyr Leu Ala Thr Asn Gly His Arg Phe Asn Arg
         275                 280                 285            
 Ile Gly Ser Phe Gly Leu Arg Val Met Asp Gln Cys Cys
     290                 295                 300    



      <210> 1251
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1251
 Met Gln Pro Gly Ala Arg Glu Gln Lys Ala Gly Leu Val Leu Lys Leu
   1               5                  10                  15    
 Leu Pro Tyr Leu Ser Cys Leu Gln Ala Val Cys Glu Ser Ile Arg Ser
              20                  25                  30        
 Trp Tyr Pro Val Thr Leu Ser Ser Ser Thr Asp Lys Glu Ser Leu Asn
          35                  40                  45            
 Leu Val Val Leu Arg Gln Leu Gly Leu Arg Ile Leu Leu Arg Leu Lys
      50                  55                  60                
 Ile Arg Asp
  65        



      <210> 1252
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 1252
 Met Met Arg Leu Ser Leu Val Val Leu Lys Val Ala Val Thr Leu Lys
   1               5                  10                  15    
 Asn Asp Phe Pro Gly Asn Gln Asn Ile Gln Val Gly Leu Lys Leu Ala
              20                  25                  30        
 Ala Lys Gln Glu Leu Trp Gln Ala Gly Glu Asp Ser Asp Ala Trp Asn
          35                  40                  45            
 Phe Leu Ser Tyr Arg Pro Thr Pro Asp Leu Lys Ala Ser Val Lys Val
      50                  55                  60                
 Ser Gly Cys Gln Ser Ala Glu Leu Ser Gly Lys Met Met Met Asn Glu
  65                  70                  75                  80
 Val Leu Ala Ala Ser Cys Val Pro Gly Leu Val Glu Ile Asn Glu Thr
                  85                  90                  95    
 Asp Val Leu Gln Ser Ser Asn Val His His Ile Gly Ser Cys Leu Arg
             100                 105                 110        
 Lys Arg
        



      <210> 1253
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1253
 Met Thr Trp Val Gln Asn Asp Arg Met Gly Val Arg Cys Phe Leu Met
   1               5                  10                  15    
 Leu Val His Ala Cys Trp Lys Ala Val Met Ser Leu Ile Cys Arg Asn
              20                  25                  30        
 Glu Glu Tyr His Gly Asn Leu Ser Val Gly Pro Thr Ala Val Ser Gln
          35                  40                  45            
 Phe Pro Gln Phe Phe Thr Ala Leu Ile Phe Gln Glu Asp Ile Ser Phe
      50                  55                  60                
 Arg Gly Lys Lys Ser Glu Ala Pro Glu Gln Pro Val Ile Cys Leu Gly
  65                  70                  75                  80
 Trp Leu Leu Trp Val Pro Gly Arg Leu
                  85                



      <210> 1254
      <211> 244
      <212> PRT
      <213> Homo sapiens


      <400> 1254
 Met Leu Arg Thr Trp Ser Ser Leu Pro Trp Thr Arg Phe Arg Val Cys
   1               5                  10                  15    
 Leu Leu Ser Leu Ser Leu Phe Leu Trp Ala Asn Arg Leu Glu Asp Ser
              20                  25                  30        
 Arg Ser Cys Gln Pro Asn Pro Met Ser Leu Thr Thr Leu Pro Gly His
          35                  40                  45            
 Arg Leu Lys Glu Ala Val Trp Leu Pro Ala Pro Ser Arg Ala Leu Ala
      50                  55                  60                
 Ser Val Lys Met Pro Thr Ser Trp Glu Asp Gln Pro Leu Lys Ser Pro
  65                  70                  75                  80
 Ile Val Lys Ala Gly Ser Asp Arg Gly Thr Lys Arg Glu Glu Glu His
                  85                  90                  95    
 Glu Ile Ile Leu Glu Pro Val Pro Leu Leu Ala Gln Thr Leu Glu Met
             100                 105                 110        
 Val Ser Gln Leu Val Arg Met Gln Leu Ala Ser Leu Pro Ser Asn Leu
         115                 120                 125            
 Ser Thr Pro Cys Thr Met Ser Pro His Leu Asp Pro Asn Gln Leu Gly
     130                 135                 140                
 Ile Leu Leu Lys Val Leu Arg Lys Glu Lys Glu Asp Gly Asp Tyr Pro
 145                 150                 155                 160
 Asp Met Met Ala Thr His Pro Ser Ser Arg Tyr Glu Ala Cys Ser Ser
                 165                 170                 175    
 Gly Ile Thr Leu Glu Lys Pro Glu Lys Leu Arg Ser Gly Lys Val Lys
             180                 185                 190        
 Glu Glu Val Asp Ser Leu Ile Gly Ser Ala Phe Pro Val Thr Pro Gln
         195                 200                 205            
 Gly Gly Trp Gln Arg Gln Ser Trp Phe Gly Lys Asp Arg Asp Gln Lys
     210                 215                 220                
 Arg Asp Glu Gln Val Ser Ala Thr Asp Ser Phe Glu Glu Tyr Phe Asn
 225                 230                 235                 240
 Gly Leu Met Pro
                



      <210> 1255
      <211> 42
      <212> PRT
      <213> Homo sapiens


      <400> 1255
 Met Pro Arg Ala Phe Val His Thr Arg Phe Leu Arg Cys Ile Phe Phe
   1               5                  10                  15    
 Phe Lys His Gln Pro Glu Pro Gly Gly Leu Met His Thr Val Glu Asp
              20                  25                  30        
 Thr Gln Lys Pro Lys Tyr Leu Gln Arg Leu
          35                  40        



      <210> 1256
      <211> 224
      <212> PRT
      <213> Homo sapiens


      <400> 1256
 Met Thr Ala Phe Ala Leu Ser Met Leu Ser Ala His His Leu Leu Pro
   1               5                  10                  15    
 Leu Pro Leu Gln Trp Leu Thr Leu Glu Thr Lys Thr Lys Thr Pro Gln
              20                  25                  30        
 Pro Phe Ser Ser Thr Ser Gln Ile Ser Thr Asp Lys Asp Lys Gly Leu
          35                  40                  45            
 Asn Pro Gln Leu Leu Lys Met Asp Pro Gly His Met Gly Trp Ser Asp
      50                  55                  60                
 Thr Pro Ala Gln Leu Ser Ala Gly Glu Glu Ala Gln Lys Arg Phe Lys
  65                  70                  75                  80
 Pro Ala Thr Ser Glu Ala Leu Asp Leu Glu Pro Glu Thr Pro Thr Ser
                  85                  90                  95    
 His Tyr Thr Cys Glu Pro Val Glu Asp Leu Asn Tyr Leu Phe Lys Arg
             100                 105                 110        
 Gln Ser Lys Asp Lys Val Asn Gly Phe Leu Leu Ser Tyr Pro Val Asn
         115                 120                 125            
 Cys Glu Leu Pro Lys Lys Arg Asn Arg Val Phe Leu Leu Phe Phe Thr
     130                 135                 140                
 Leu Asn Val His Arg Tyr Ala Thr Gln Lys Ala Thr His Arg Arg Gln
 145                 150                 155                 160
 Val Ala Tyr Val Thr Cys Thr Val Val Gln Glu Ser Gln Val Thr Ile
                 165                 170                 175    
 Pro Thr Met Val Ser Arg Leu Gly Leu Ala Gln Lys His Pro Leu Ser
             180                 185                 190        
 Leu Gly Gly Leu Ile Leu Leu Thr Thr Gly His Leu Pro Asp His Glu
         195                 200                 205            
 Tyr Ser Ala Asn Cys Pro Arg Val Thr Lys Ala Ala Gln Ser Arg Val
     210                 215                 220                





      <210> 1257
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 1257
 Met Gly Pro Ala Thr Trp Trp Val Leu Glu Ala Leu Asp Leu Asp Leu
   1               5                  10                  15    
 Ala Gly Ala Leu Val Gly Ala Trp Glu Val Asp Arg Pro Val Lys Gly
              20                  25                  30        
 Ala Leu Ser Ser Gln Lys Pro Asp Arg Phe Glu Gly Lys Gly Thr Pro
          35                  40                  45            
 Glu Glu Phe Gly Pro Arg Val Ala Cys Asp Gln Leu Phe Arg Glu Ser
      50                  55                  60                
 Ser Val Ser His Cys Gly Ser Thr Trp Lys Lys Lys Gln Lys Gln Ser
  65                  70                  75                  80
 Gly Lys Gly Arg Asn Ser Pro Glu Gln Glu Lys Lys Phe Leu Leu Lys
                  85                  90                  95    
 His Leu Phe Cys Phe Pro Val Pro Gly Ile Ser Ile Ile His
             100                 105                 110



      <210> 1258
      <211> 241
      <212> PRT
      <213> Homo sapiens


      <400> 1258
 Met Arg Gly Leu Val Val Phe Leu Ala Val Phe Ala Leu Ser Glu Val
   1               5                  10                  15    
 Asn Ala Ile Thr Arg Val Pro Leu His Lys Gly Lys Ser Leu Arg Arg
              20                  25                  30        
 Ala Leu Lys Glu Arg Arg Leu Leu Glu Asp Phe Leu Arg Asn His His
          35                  40                  45            
 Tyr Ala Val Ser Arg Lys His Ser Ser Ser Gly Val Val Ala Ser Glu
      50                  55                  60                
 Ser Leu Thr Asn Tyr Leu Asp Cys Gln Tyr Phe Gly Lys Ile Tyr Ile
  65                  70                  75                  80
 Gly Thr Leu Pro Gln Lys Phe Thr Leu Val Phe Asp Thr Gly Ser Pro
                  85                  90                  95    
 Asp Ile Trp Val Pro Ser Val Tyr Cys Asn Ser Asp Ala Cys Gln Arg
             100                 105                 110        
 Ile Ala Ser Ile Glu Ala Ile Phe Leu Gln Gly Leu Leu Arg Gly Ser
         115                 120                 125            
 Ala Leu Ala Gly Thr Val Ser Gly Glu Lys Ile Leu Arg Ala Pro Leu
     130                 135                 140                
 Thr Leu Gly Leu Cys Phe Arg Lys Pro Pro Thr Leu Arg Ser Val Gln
 145                 150                 155                 160
 Val Leu His Pro Gln Asn Met Gly Lys Ser Leu Ser Ile Gln Tyr Gly
                 165                 170                 175    
 Thr Gly Ser Met Arg Gly Leu Leu Gly Tyr Asp Thr Val Thr Asp Leu
             180                 185                 190        
 Val Glu Val Met Ile Leu Leu Gln Val Ser Asn Ile Val Asp Pro His
         195                 200                 205            
 Gln Thr Val Gly Leu Ser Thr Gln Glu Pro Gly Asp Val Phe Thr Tyr
     210                 215                 220                
 Ser Glu Phe Asp Gly Ile Leu Gly Leu Ala Tyr Pro Ser Leu Ala Ser
 225                 230                 235                 240
 Glu
    



      <210> 1259
      <211> 132
      <212> PRT
      <213> Homo sapiens


      <400> 1259
 Met Gly Val Leu Leu Ala Leu Gly Leu Glu Ala Gly Val Arg Leu Ala
   1               5                  10                  15    
 Phe Leu Ala Ala Gln Pro Gly Gln Ser Ser Lys Thr Ala Ala Ala Ala
              20                  25                  30        
 Phe Thr Leu Trp Pro Arg Ala Leu Gly Gly Val Ala Gln Val Ala Pro
          35                  40                  45            
 Thr Arg Arg Phe Ser Pro Val Ser His Leu Lys Arg Lys Glu Ser Trp
      50                  55                  60                
 Gly Ala Ser Cys Ala Asp Ser Ala Pro Val Ala Trp Ser Arg Trp Ala
  65                  70                  75                  80
 Leu Gly Val Gly Gln Gly Trp Cys Arg Arg Gln His Lys Ala Thr Gly
                  85                  90                  95    
 Ser Met His Ser Phe Ala Gln Gln Ala Phe Ala Ser Phe Pro Glu Glu
             100                 105                 110        
 Val Lys Glu Ala Thr Arg Asn Leu Gly Ala Val Glu Pro Ile Gly Asp
         115                 120                 125            
 Ser Arg Leu Cys
     130        



      <210> 1260
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 1260
 Met Ile Phe Cys Leu Ile Leu Asp Ile Cys Ser Leu Leu Thr Glu Ser
   1               5                  10                  15    
 Lys Ser Val Asn Tyr Gln Ile Gln Ser Asn His Gly Ser Ser Pro Val
              20                  25                  30        
 Ser Val Val Thr Ser Lys Pro Ser Ser Asp Gln Lys Phe Ala Gln Thr
          35                  40                  45            
 Arg Phe Gln Thr Glu Ile Cys Arg Ala Ser Glu Ser Gln Arg Glu Leu
      50                  55                  60                
 Thr Thr Ile Ser Val Ala Ser Arg Lys Gln Trp Thr Ser
  65                  70                  75        



      <210> 1261
      <211> 169
      <212> PRT
      <213> Homo sapiens


      <400> 1261
 Met Val Ile Val Gly Leu Ala Ala Gly Val Leu Leu Val Gly Pro Gly
   1               5                  10                  15    
 Asp Gly Gly Leu Ile Ser Glu Gly Val Val Arg Glu Asp Leu Met Cys
              20                  25                  30        
 Gly Val Trp Ser Ala Gly Thr Trp Ser Val Gly Thr Ala Glu Arg Cys
          35                  40                  45            
 Leu Glu Lys Pro Gly Ala Leu His Val Ile Glu Gly Pro Leu Asp Ser
      50                  55                  60                
 Trp Asp Gly Pro Val Met Pro Asn Gly Pro Val Lys Asn His Lys Gly
  65                  70                  75                  80
 Glu Gln Gln Glu Val Pro Ser Lys His Pro Gln Met Ala Leu Glu Ile
                  85                  90                  95    
 Cys Leu Cys Leu Asp Phe Leu Tyr Tyr Pro Phe Leu Arg Gly Asp Ala
             100                 105                 110        
 Ser Ala Gly Pro Val Thr Trp Cys Thr Thr Ser Asp Thr Ile Ile Leu
         115                 120                 125            
 Gln Gln His Arg Thr Leu Thr Ser Gln Gly Val Asp Asp Phe Leu Lys
     130                 135                 140                
 Ala Lys Ala Thr Phe Lys Ala Ser Asp Phe Ile Asp Ala Leu Val Leu
 145                 150                 155                 160
 Ser Lys Phe Leu Glu Ala Leu Ile Glu
                 165                



      <210> 1262
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1262
 Met Gly His Val Ala Arg Ser Met Trp Arg Arg Ser Leu Leu Leu Thr
   1               5                  10                  15    
 Ser Ala Glu Ser Gln Gly Leu Thr Gln Asp Glu Lys Pro His Phe Ile
              20                  25                  30        
 Lys Gly Ser Ser Val Val Ser His Asp Pro Pro Glu Gly Trp Gly Val
          35                  40                  45            
 Gly Ile Trp Leu Leu Leu Pro Pro Lys Gly Gly Leu Trp Gly Thr Arg
      50                  55                  60                
 Leu Ile Tyr Pro Arg Thr Gln Glu Gly Thr Val Ser Ala Met Cys Lys
  65                  70                  75                  80
 Met Gly Gly Asn Pro Gln Ala Ser Ser Gln Met Gln Ser Ser Asp Ile
                  85                  90                  95    
 Gly Val Lys Ser Gly Leu Gly Gln Glu Leu Phe
             100                 105        



      <210> 1263
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1263
 Met Lys Pro Val Ser Arg Arg Thr Leu Asp Trp Ile Tyr Ser Val Leu
   1               5                  10                  15    
 Leu Leu Ala Ile Val Leu Ile Ser Trp Gly Cys Ile Ile Tyr Ala Ser
              20                  25                  30        
 Met Val Ser Ala Arg Arg Gln Leu Arg Lys Lys Tyr Pro Asp Lys Ile
          35                  40                  45            
 Phe Gly Thr Asn Glu Asn Leu
      50                  55



      <210> 1264
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1264
 Met Trp Met Asp Ala Gly Trp Leu Leu Gly Ser Trp Leu Thr Trp Ala
   1               5                  10                  15    
 Gly Ser Gln Gly Pro Val Phe Arg Ala Arg Ala Ile Gln Ile Cys Pro
              20                  25                  30        
 Ser Ala Lys Leu Arg Phe Thr Val Glu Glu Pro Leu Gly Lys Asn Asn
          35                  40                  45            
 Asp Ile Ile Leu Leu Ser Val Lys Pro Leu Leu Cys Ser Phe Cys Asp
      50                  55                  60                
 Ser Lys Gly Lys Thr Asp Glu Ser Asn Glu Ala Gln Arg Gly Gln Glu
  65                  70                  75                  80
 Ala Val Thr Gln Glu Asp His Thr Gly Arg Pro Gly Gly Lys Gln Ile
                  85                  90                  95    
 Ser Gln Asp Arg Arg Ala Asn Lys Ser His Met Gly Lys Gly Ser Glu
             100                 105                 110        
 Lys Ser Tyr Asn Ile Cys Asn Thr Lys Asp Leu Val Leu Tyr Val
         115                 120                 125        



      <210> 1265
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1265
 Met Leu Val Pro Val Leu Ile Leu Ser Pro Cys Leu Val Gly Ile Glu
   1               5                  10                  15    
 Pro Trp Glu Val Ser Pro His Thr Asn Ser Thr Ser Ser Tyr Glu Ser
              20                  25                  30        
 Thr Pro Lys Ser Tyr Pro Leu Gly Thr Ala Ala Lys Ala Ala Ser Gly
          35                  40                  45            
 Gln Ser Pro Ser Thr Thr Ser Pro Leu Pro Glu Thr Ala Pro Ser Thr
      50                  55                  60                
 Leu His Glu Arg Gly Leu Glu Asn Val Val Cys Ser Asp Lys Asp Leu
  65                  70                  75                  80
 Arg Gln Ala Thr Gly Tyr Ser Ala Ala Glu Lys Ser Lys Pro Pro Gly
                  85                  90                  95    
 Leu Cys Thr Arg Ala Phe Cys Pro Glu Ala Ile Pro Asp Ala Gln Asp
             100                 105                 110        
 Trp Val Lys Cys Gln Pro Leu Gly Ser Leu Ser Ala Leu Asn Phe
         115                 120                 125        



      <210> 1266
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1266
 Met Met His Ala Lys Phe Ile Phe Val Ala Ile Glu Thr Phe Met Asp
   1               5                  10                  15    
 Val Ala Phe Ala Val Phe Leu Pro Pro Gly Pro Leu Gly Ile Pro Val
              20                  25                  30        
 Gln Cys Ile Lys Pro Tyr His Gly Met Ala Gly Thr Gln Cys Ser Thr
          35                  40                  45            
 Gly Asn Glu Glu Cys Glu Pro Val Gly Pro Ala Ala Pro Asp Asn Ala
      50                  55                  60                
 Ala Ser Ser Asp Asn Thr Asp Asn Leu Phe Leu Ala Met Leu Ser Val
  65                  70                  75                  80
 Val His Cys Asn Ser Cys Lys Asp Ala Lys Leu Glu His Lys Leu
                  85                  90                  95



      <210> 1267
      <211> 275
      <212> PRT
      <213> Homo sapiens


      <400> 1267
 Met Ala Phe Leu Thr Asn Val Leu Ala Phe His Phe Ile Phe Val Phe
   1               5                  10                  15    
 Val Lys Glu Gly Lys Pro Glu Lys Phe Ser Phe Gly Leu Leu Asp Leu
              20                  25                  30        
 Pro Phe Arg Val Gly Val Pro Phe Asn Ile Pro Leu Glu Phe Gln Asp
          35                  40                  45            
 Glu Phe Gly His Thr Ser Gln Leu Val Thr Asp Ile Gln Pro Val Leu
      50                  55                  60                
 Glu Ala Ser Gly Leu Ser Leu His Tyr Glu Glu Ile Thr Asn Gly Pro
  65                  70                  75                  80
 Asn Cys Val Ile Arg Gly Val Thr Ala Lys Gly Pro Val Asn Ser Cys
                  85                  90                  95    
 Gln Gly Lys Val Glu Val Leu Asp Glu Ser Asp Asn Ile Thr Ala Gln
             100                 105                 110        
 Pro Lys Leu Ile Val His Cys Lys Ser Cys Lys Asp Val Ala Pro Val
         115                 120                 125            
 Glu Lys Thr Ile Lys Leu Leu Pro Ser Ser His Val Ala Arg Leu Gln
     130                 135                 140                
 Ile Phe Ser Val Glu Gly Gln Lys Ala Ile Gln Ile Lys His Gln Asp
 145                 150                 155                 160
 Glu Val Asn Trp Ile Ala Gly Asp Ile Met His Asn Leu Ile Phe Gln
                 165                 170                 175    
 Met Tyr Asp Glu Gly Glu Arg Glu Ile Asn Ile Thr Ser Ala Leu Ala
             180                 185                 190        
 Glu Lys Ile Lys Val Asn Trp Thr Pro Glu Ile Asn Lys Glu His Leu
         195                 200                 205            
 Leu Gln Gly Leu Leu Pro Asp Val Gln Val Pro Thr Ser Val Lys Asp
     210                 215                 220                
 Met Arg Tyr Cys Gln Val Ser Phe Gln Asp Asp His Val Ser Leu Glu
 225                 230                 235                 240
 Ser Ala Phe Thr Val Ser Tyr Asn Asn Tyr Arg Ser Val Arg Lys Ser
                 245                 250                 255    
 Asp Ser Ser Ile Phe Thr Lys Phe Phe Ile Phe Phe Val Asn Cys Trp
             260                 265                 270        
 Gly Trp Thr
         275



      <210> 1268
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1268
 Met Leu Ala Ser Pro Leu Trp Leu Gln Ala Leu Ser Leu Ala Ala Gly
   1               5                  10                  15    
 Thr Trp Arg Pro Arg Leu Gly Ser Gly Gln Ala Gly Asn Ser Glu Met
              20                  25                  30        
 Arg Ala Gly Phe Leu Pro Gly Ala Gly Ser Gln Val Arg Ala Gln Leu
          35                  40                  45            
 Gln Asp Arg Leu Pro Lys Thr Thr Glu Thr Lys Gly Ala Leu Trp Pro
      50                  55                  60                
 His Thr Glu Leu Cys Gly Met Trp Ser Ile Ala Pro Gly Ala Glu Asn
  65                  70                  75                  80
 Gln Glu Leu Gln Ile Asp Ser Pro Leu Leu Gly Gln Leu Ser Asn Gln
                  85                  90                  95    
 Val Trp Arg Glu Asp Gly Tyr Gly Lys Ala Phe Arg Leu Arg Thr Leu
             100                 105                 110        
 Ser Ser Met Gly Ile Thr Glu Glu Ala Asn Glu Asn Val Leu Ile
         115                 120                 125        



      <210> 1269
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1269
 Met Lys Lys Gly Met Phe Cys Phe Arg Arg Glu Phe Gly Phe Leu Phe
   1               5                  10                  15    
 Thr Phe Leu Tyr Met Gln Ile Thr Tyr Ser Ala Ile Val Gly Ile Cys
              20                  25                  30        
 Leu Asp Leu Ser Ser Ala Tyr Cys Asn Ser Ala Ser Arg Ile Asn Pro
          35                  40                  45            
 Gly Ile Thr Arg Met Thr Ala Val Asp Gln Trp Gln Leu Lys Pro Trp
      50                  55                  60                
 Ile Lys Gly Asp Ser Leu Leu His Asn Tyr Glu Glu Ser Ser Ala Lys
  65                  70                  75                  80
 Arg Phe Phe Ser Met Pro Leu Phe Trp Lys Arg Asn Leu Ile Pro Arg
                  85                  90                  95    
 Asp His Asn Phe Arg Arg Ala Asn Lys Glu Glu Val Gly Lys Lys Lys
             100                 105                 110        
 Thr Cys Leu Asp Ser His Glu Gly Gln Ile Asn Thr Pro Asn Gly Ser
         115                 120                 125            
 Arg Thr
     130



      <210> 1270
      <211> 196
      <212> PRT
      <213> Homo sapiens


      <400> 1270
 Met Arg Thr Gln Val Pro Gly Val Pro Gly Trp Val Leu Leu Val Phe
   1               5                  10                  15    
 Thr Ala Leu Gly Leu Thr His Tyr Ser Val Ser Gln Glu Arg Ile Arg
              20                  25                  30        
 Pro Glu Ile Cys Val Pro Arg Gly Gly Gly Glu Arg Arg Arg Lys Glu
          35                  40                  45            
 Gly Asn Ser Ser Thr Gly Phe Arg Ala Gly Ser Trp Gly Ala Gln Ala
      50                  55                  60                
 Gly Cys Gly Gly Gln Ser Arg Ala Ala Thr Pro Gly Arg Ile Leu Arg
  65                  70                  75                  80
 Ala Pro Thr Ala Pro Leu Pro Glu Arg Leu Pro Pro Ser Pro Gly Ser
                  85                  90                  95    
 Gly Arg Cys Ala Gly Arg Gly Ala Arg Val Arg Arg Ala Ala Gly Glu
             100                 105                 110        
 Thr Arg Trp Ala Asp Pro Arg Ala Ala Leu Asp Arg Thr Asp Leu Pro
         115                 120                 125            
 Ile Asn Tyr Arg Asp Glu Lys Ser Ser Gly Ile Arg Lys Arg Glu Leu
     130                 135                 140                
 Ile Pro Trp Leu Ala Ala Ile Ala Pro Val His Gly Ala Thr Tyr Met
 145                 150                 155                 160
 Cys Asp Ile Arg Val Arg Ser His Leu Thr Thr Arg Phe Leu Asp Ala
                 165                 170                 175    
 Ala Ala Thr Val Ile Gln Thr Tyr Arg His Ser Pro Ala Pro Gly Pro
             180                 185                 190        
 Leu His Gly Leu
         195    



      <210> 1271
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1271
 Met Pro Leu Pro Pro Asp Phe Ala Cys Gly Phe Val Ile Leu Val Gly
   1               5                  10                  15    
 Pro Leu Arg Leu Leu Ala Ala Arg Asp Val Pro Val Asp Pro Val Glu
              20                  25                  30        
 Arg Glu Glu Ala Trp Lys Gly Thr Thr Ile Phe Leu Asp Val Gly Leu
          35                  40                  45            
 Leu Leu Ser Cys Arg Thr Met Cys Tyr Arg Gly Ala Phe Val Leu Gly
      50                  55                  60                
 Trp Ser Val Val Leu Leu Ile Leu Glu Lys Arg Thr Leu Met Met Gly
  65                  70                  75                  80
 Met Arg Leu Pro Leu Leu Pro Ala Asp Ala Ser Pro His Val Ile Glu
                  85                  90                  95    
 Asp Phe Ala Asn Pro Lys Trp Asn Arg Arg Glu Asn Asp Gly Gln Leu
             100                 105                 110        
 Asp Arg Thr Gln Gly Glu Thr Gln Lys Glu Thr His Gln Arg Pro Ala
         115                 120                 125            
 Asp Lys Gln Glu Ile Pro Phe
     130                 135



      <210> 1272
      <211> 104
      <212> PRT
      <213> Homo sapiens


      <400> 1272
 Met Arg Gly Val Leu Arg Val Leu Gly Asn Leu Gln Met Ala Ala Ala
   1               5                  10                  15    
 Gly Arg Asn Trp Gln Cys Gln Gly Thr Ser Ser Glu Arg Thr Ala Glu
              20                  25                  30        
 Gly Ala Asp Leu Ala Ser Val Leu Arg Met Lys His Ala Val Gln Gly
          35                  40                  45            
 Ser Lys Leu Gln Val Asn Ser Lys His Glu Ala Ala Thr Leu Glu Met
      50                  55                  60                
 Gly Cys Leu His Arg Leu Gly Leu Trp Ala Ala Ile Leu Cys Gln Ala
  65                  70                  75                  80
 Asp Ala Leu Pro Pro Ala Pro Leu Thr Trp Ala Ser His Phe Leu Ser
                  85                  90                  95    
 Pro Trp Pro Pro Ala Pro His Val
             100                



      <210> 1273
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1273
 Met Ser Pro Leu Arg Pro Leu Leu Leu Ala Leu Ala Leu Ala Ser Val
   1               5                  10                  15    
 Pro Cys Ala Gln Gly Ala Cys Pro Ala Ser Ala Asp Leu Lys His Ser
              20                  25                  30        
 Asp Gly Thr Arg Thr Cys Ala Lys Leu Tyr Asp Lys Ser Asp Pro Tyr
          35                  40                  45            
 Tyr Glu Asn Cys Cys Gly Gly Ala Glu Leu Ser Leu Glu Ser Gly Ala
      50                  55                  60                
 Asp Leu Pro Tyr Leu Pro Ser Asn Trp Ala Asn Thr Ala Ser Ser Leu
  65                  70                  75                  80
 Val Val Ala Pro Arg Cys Glu Leu Thr Val Trp Ser Arg Gln Gly Lys
                  85                  90                  95    
 Ala Gly Lys Thr His Lys Phe Ser Ala Gly Thr Tyr Pro Arg Leu Glu
             100                 105                 110        
 Glu Tyr Arg Arg Gly Ile Leu Gly Asp Trp Ser Asn Ala Ile Ser Ala
         115                 120                 125            
 Leu Tyr Cys Arg Cys Pro Ala Ala Gln Ser Ser Glu Pro Thr Pro Gly
     130                 135                 140                
 Pro Gly Pro Ser Ser Ala
 145                 150



      <210> 1274
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1274
 Met Ala Ser Phe Trp Val Trp Ala Gln Cys His Ile Phe His His Phe
   1               5                  10                  15    
 Leu Met Tyr Pro Thr Ser Thr Glu Glu Thr Ala Trp Arg Glu Cys Lys
              20                  25                  30        
 Arg Lys Ala Glu Lys Asp Glu Ile Ala Ile His Phe Thr Arg Asp Ala
          35                  40                  45            
 Phe Lys Asn Ile Ser Lys Leu Leu Ala Asn Gln Ser Arg Lys Asp Leu
      50                  55                  60                
 Asp Pro Ala Arg Asp Leu Leu Val Leu Ser Gln Gly His Gln Thr Asn
  65                  70                  75                  80
 Ile Leu Asp Ile Ile Leu Ile His Lys Glu Ala Leu Thr Lys Val Thr
                  85                  90                  95    
 Glu Asn Arg Gln His Val Ala Glu Gly Lys Thr Glu Val Gln Arg Leu
             100                 105                 110        
 Met Val Ser Leu Ser Gln Glu Gln Asp Phe Phe Gly His Phe Gly
         115                 120                 125        



      <210> 1275
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1275
 Met Lys Ile Phe Phe Phe Ala Phe Leu Met Lys Leu Ser Ile Phe Ile
   1               5                  10                  15    
 Met Val Leu Ala Ile Thr Gly Met Cys Cys Glu Ala Ala Leu Lys Ala
              20                  25                  30        
 Ser Asp Lys Glu Lys Thr Cys Ala Leu Pro Phe Leu Ser Pro Ser Leu
          35                  40                  45            
 Glu Ser Val Thr Ser Asp Lys Val Gly His Ser Asp Leu Tyr Arg Val
      50                  55                  60                
 Gln Gly Ile
  65        



      <210> 1276
      <211> 141
      <212> PRT
      <213> Homo sapiens


      <400> 1276
 Met Arg Arg Ile Ile Val Gly Leu Ile Phe Leu Ile Ile Trp Ala Cys
   1               5                  10                  15    
 Ile Val Lys Thr Ser Thr Asp Phe Pro His Met Glu Asp Cys Ser Gln
              20                  25                  30        
 Cys Ile His Gln Val Thr Glu Arg Ser Ile Ala Ile Gly Asn Trp Gln
          35                  40                  45            
 Asp Asp Glu Trp Leu Pro Glu Arg Ile Thr Gln Tyr Tyr Gly Pro Ala
      50                  55                  60                
 Thr Trp Ala Gln Tyr Gly Ser Trp Gly Tyr Tyr Asn Pro Ile Tyr Met
  65                  70                  75                  80
 Leu Asn Gln Met Ile Trp Leu Gln Ala Val Leu Glu Ile Thr Thr Asn
                  85                  90                  95    
 Lys Thr Gly Arg Ala Leu Thr Ile Leu Ala Trp Gln Glu Thr Gln Met
             100                 105                 110        
 Arg Asn Pro Thr Tyr Gln Asp Arg Leu Ala Leu Asp Tyr Leu Leu Ala
         115                 120                 125            
 Ala Glu Gly Gly Val Cys Gly Lys Phe Asn Leu Thr Asn
     130                 135                 140    



      <210> 1277
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 1277
 Met His Tyr Leu Ile Cys Ser Ser Lys Ser Ser Ser Pro Ile Thr Arg
   1               5                  10                  15    
 Arg Ile Leu Tyr Cys Thr Leu Ile Leu Pro Met Tyr His Leu Glu Pro
              20                  25                  30        
 Phe Phe Ser Tyr Ile Phe Leu Asn Leu Gln Leu Met Ile Leu Gln Val
          35                  40                  45            
 Leu His Leu Tyr Trp Gly Tyr Tyr Ile Leu Lys Met Leu Asn Arg Cys
      50                  55                  60                
 Ile Phe Met Lys Arg Ser Gln His Gln Pro His Gln Pro Gln Asp Ser
  65                  70                  75                  80
 Ser Ser Arg Trp Tyr Asn Gln Gln Leu Pro Gly Pro Ala Thr Tyr Pro
                  85                  90                  95    
 Glu Leu Gly Asp Gln Thr Phe Met Thr Val Arg Leu Asn Met Pro Ser
             100                 105                 110        
 Arg Val Ala Gly Gly Gly Tyr Ser Thr Pro Gly Ser Gln Cys Ser Ser
         115                 120                 125            
 Ala Ile Ile Leu Gln Gln Thr Ser Pro Pro His Gly Ala Glu Thr Asp
     130                 135                 140                
 Thr Asp Thr Met Leu Tyr Val Asp Ala Ala Glu Leu
 145                 150                 155    



      <210> 1278
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1278
 Met Ser Ser Trp Ala Val Gly Asp Leu Pro Gly Leu Leu Leu Val Cys
   1               5                  10                  15    
 Cys Leu Val Thr Pro Gly Gly Leu His Gly Asp Cys His Gly Ala Tyr
              20                  25                  30        
 Gly Ala Gln Ser Asp Pro Asp Ser Gln Gln Ala Gln Lys Pro Asp Leu
          35                  40                  45            
 Ala Val Ala Gly Lys Thr Asp Thr Gly Thr Lys Gly His
      50                  55                  60    



      <210> 1279
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 1279
 Met Ser Thr Cys Leu Thr Glu Gln Gln Asn Phe Leu Arg Ile Leu Asn
   1               5                  10                  15    
 Gln Leu Leu Leu Ser Ser Ile Phe Leu Leu Leu Ser Leu Thr Leu Phe
              20                  25                  30        
 Ser Asn Met Ile Trp Asp Gln Ser Ile Asp Glu Thr Val Ser Thr Lys
          35                  40                  45            
 Gly Tyr Thr Cys Gln Gln Phe Cys His Asp Ser Thr Pro Asn Lys Gly
      50                  55                  60                
 Asp Arg Val Thr Tyr Asn Leu Thr Arg Pro Pro Tyr Cys Cys Val Pro
  65                  70                  75                  80
 Phe Pro Leu Ala Gly Thr Gly Pro Gln Ile Leu Tyr Leu Ser Arg Leu
                  85                  90                  95    
 Ala Ser Asn Leu Glu Leu Leu Lys Arg Gly Lys Gly Arg Gly Glu Gln
             100                 105                 110        
 Arg Lys Glu Glu Val Thr Cys Gly Met Val Arg Lys Val Lys Arg Pro
         115                 120                 125            
 Ser Asn Lys Glu Glu Glu Gln Ala Leu Thr
     130                 135            



      <210> 1280
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 1280
 Met Cys Cys Trp Pro Leu Leu Leu Leu Trp Gly Leu Leu Pro Gly Thr
   1               5                  10                  15    
 Ala Ala Gly Gly Ser Gly Arg Thr Tyr Pro His Arg Thr Leu Leu Asp
              20                  25                  30        
 Ser Glu Gly Lys Tyr Trp Leu Gly Trp Ser Gln Arg Gly Ser Gln Ile
          35                  40                  45            
 Ala Phe Arg Leu Gln Val Arg Thr Ala Gly Tyr Val Gly Phe Gly Phe
      50                  55                  60                
 Ser Pro Thr Gly Ala Met Ala Ser Ala Asp Ile Val Val Gly Gly Val
  65                  70                  75                  80
 Ala His Gly Arg Pro Tyr Leu Gln Thr Pro Pro Arg Leu His Thr Cys
                  85                  90                  95    
 Asn Thr Pro Arg Phe Ile Pro Asp Gly Lys Gly Glu Gly Pro Arg Leu
             100                 105                 110        
 Trp Leu Trp Gly Pro Asn Gly Thr Ala Leu Arg Gly Gly Lys Gly Gln
         115                 120                 125            
 Ser Ala Leu Val Arg Arg Gly Leu Ala Val
     130                 135            



      <210> 1281
      <211> 217
      <212> PRT
      <213> Homo sapiens


      <400> 1281
 Met Gly Thr Gln Thr Leu Ala Ile Phe Gly Ser Ala Val Gly Cys Leu
   1               5                  10                  15    
 Ala Gln Ala Leu Trp Val Gly Ser Ile Trp Gly Lys Gly His Gln Glu
              20                  25                  30        
 Lys Leu His Leu Gly Ser Pro Trp Leu Ala Leu Pro Gly Ala Ala Gly
          35                  40                  45            
 Ala Glu Cys Pro Leu Ser Arg Thr Ser Glu Pro Ser Gly Arg His Glu
      50                  55                  60                
 Asn Met Cys Ser Trp Lys Pro Gln Lys His Pro Gly Asp Gly Asp Leu
  65                  70                  75                  80
 Cys Lys Leu Ser Arg Pro Gly Tyr Phe Asp Leu Glu Gly Asn Gly Gly
                  85                  90                  95    
 Ala Gly Glu Phe Cys Pro Ala Val Pro Arg Gly Ser Leu His Thr Thr
             100                 105                 110        
 Asp Pro Tyr Ala Ser Lys Val Gly Ala Leu Ala Gly Ser Ser Cys Thr
         115                 120                 125            
 Ser Cys Arg Val Asp Ala Gly Arg Cys Cys Leu Thr Arg Ile Leu Gly
     130                 135                 140                
 Asp Thr Asp Pro Gly Ser Ser Gln Arg Phe Gln Pro Ala Val Gly Leu
 145                 150                 155                 160
 Asp Pro Cys Ile Leu Ser Arg Phe Ile Phe Gln Val Ala Arg Arg Cys
                 165                 170                 175    
 Trp Ser Gly Asn Gln Lys Ala Tyr Glu Ile Ile Cys Gln Thr Met Gln
             180                 185                 190        
 Glu Asn Ser Thr Leu Val Val Thr Leu Pro His Lys Val Glu Asp Glu
         195                 200                 205            
 Arg Val Leu Gln Gln Ala Leu Gln Leu
     210                 215        



      <210> 1282
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1282
 Met Arg Glu Gly Trp Cys Trp His Phe Lys Thr Val Phe Ala Ile Leu
   1               5                  10                  15    
 Phe Ser Ala Ser Val Ser Asp Met Lys Leu Lys Pro Gly Thr Val Ile
              20                  25                  30        
 Ala His Arg Ile Phe Gly Ser Tyr Glu Val Ala Asn Phe Glu Val Pro
          35                  40                  45            
 Val Glu Ala Gly Val Ile Leu Phe Gln Tyr Leu Lys Ser Ser Tyr Leu
      50                  55                  60                
 Gly Gly Gly Lys Asn Gly Ser Glu Ala Lys Val Val Thr Gly Lys Thr
  65                  70                  75                  80
 Ala Ala Val Thr Pro Ile Ser Gln Asp Lys Gly Met Leu Gly His Ser
                  85                  90                  95    
 Cys Gly Leu Asp Asn Ile His Gly Phe Val Cys Val Gln Met Val Thr
             100                 105                 110        
 Glu Trp Pro Phe Leu Arg Leu Ala Phe His Gly Ile Val Asp Val
         115                 120                 125        



      <210> 1283
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1283
 Met Met Gln Phe Phe Leu Val Thr Leu Trp Ala Thr Asp Leu Gln Leu
   1               5                  10                  15    
 Pro Ile Pro Pro Thr Ser Ile Ala Arg Val Gln Ala His Cys Arg Arg
              20                  25                  30        
 His Pro Asp Tyr Ser Gly Ala Asp Leu Thr Ala Thr Met Thr Val Cys
          35                  40                  45            
 Ser Ala Pro Thr Phe Ser Arg Val Pro Ile Ser Cys Pro Thr Phe Lys
      50                  55                  60                
 Lys Asn Glu Val Met Leu Pro Ala Ser Gly Val His Ser Leu Met His
  65                  70                  75                  80
 Tyr Leu Ile Lys Asp Thr Glu Ala His
                  85                



      <210> 1284
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 1284
 Met Ala Leu Arg Ser Leu Met Phe Leu Ala Arg Phe Ala His Gln Pro
   1               5                  10                  15    
 Asn Thr Ser Gln Thr Leu Ile Val Ser Ile Gln Pro Leu Glu Asp Thr
              20                  25                  30        
 Glu His Leu Thr Phe Met Leu Ile Lys Ser Pro Gln Ala Pro Glu Glu
          35                  40                  45            
 Leu Ser Glu His Leu Ser Ile Ser Tyr Ser Trp Asp Gln Phe Gly Lys
      50                  55                  60                
 Thr His Ala Leu Leu Ser Phe Cys Arg His Lys Thr Pro Ala Leu Ala
  65                  70                  75                  80
 Lys Pro Gln Arg Pro Gln Glu Tyr Cys Thr Cys Tyr Glu
                  85                  90            



      <210> 1285
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1285
 Met Leu Pro Ser Lys Leu Arg Gln Pro Phe Thr Leu Leu Ile Thr Lys
   1               5                  10                  15    
 Leu Gln Gln Pro Phe Thr Leu Leu Ile Met Thr Gly Gly Ala Gln His
              20                  25                  30        
 Ala Leu Lys Pro Pro Ser Ile Cys Ser Arg His Pro Thr Val Ala Ser
          35                  40                  45            
 Pro Glu Ser Ser Glu Ile Cys Leu Leu Leu Phe Pro Phe Ser Cys Ser
      50                  55                  60                
 Phe Leu Gln Glu Pro Arg Arg Ser Leu Phe Pro Met Pro Ser Val Glu
  65                  70                  75                  80
 Ser Ala Arg Cys Asp Leu Thr Ser Leu Asn Thr Phe Ile Thr Ile His
                  85                  90                  95    
 His Leu His Gly Asn Ser Gln Gly His Ala His Lys Pro Glu Leu Val
             100                 105                 110        
 Leu Asp Leu Ala Pro Glu Gln Arg Ala Leu Ala Thr Asn Tyr Cys Ser
         115                 120                 125            
 Phe Met Leu Glu Leu Ser His Arg Thr Thr Asp Met Val Phe Thr Leu
     130                 135                 140                
 Asn Pro Trp Pro Gln Thr Pro Thr Ile
 145                 150            



      <210> 1286
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 1286
 Met Ala Leu Leu Leu Cys Phe Val Leu Leu Cys Gly Val Val Ala Phe
   1               5                  10                  15    
 Val Ser Val Leu Ser Ser Val Thr Arg Phe Gln Lys Pro Trp Ala Ala
              20                  25                  30        
 Ser Phe Gln Val Ser Ser Arg Pro Gly Gly Glu Ala Glu Leu Gln Thr
          35                  40                  45            
 Pro Leu Phe Asn Gly His Gly Ala Ala Arg Cys Leu Gly Ser Ala Arg
      50                  55                  60                
 Leu Pro Leu Gly Lys Arg Arg
  65                  70    



      <210> 1287
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1287
 Met Ala Leu Gly Lys Val Leu Ala Met Ala Leu Val Leu Ala Leu Ala
   1               5                  10                  15    
 Val Leu Gly Ser Leu Ser Pro Gly Ala Arg Ala Gly Asp Cys Lys Gly
              20                  25                  30        
 Gln Arg Gln Val Leu Arg Glu Ala Pro Gly Phe Val Thr Asp Gly Ala
          35                  40                  45            
 Gly Asn Tyr Ser Val Asn Gly Asn Cys Glu Trp Leu Ile Glu Glu Pro
      50                  55                  60                
 Cys Pro Ser Gly Ser Phe Ser Val Lys Thr Cys Gly Leu Thr Trp Gly
  65                  70                  75                  80
 Ile Ala Glu Ile Arg Gly Ile Cys Thr Arg Glu Gln Lys Gly Ile Pro
                  85                  90                  95    
 Gly Lys Asn Ser Cys Ala Lys Ala Gly Lys Arg Glu Ser Asp Ala Phe
             100                 105                 110        
 Glu Glu Leu Glu Ile Gln Cys Val Lys Thr
         115                 120        



      <210> 1288
      <211> 365
      <212> PRT
      <213> Homo sapiens


      <400> 1288
 Met Val Ala Cys Phe Leu Gln Ile Ile Ser Phe Tyr Tyr Val Phe Phe
   1               5                  10                  15    
 Phe Tyr Ser Thr Gln Ile Arg Asn Gln Ser Lys Ala Ser Gly Ser Gly
              20                  25                  30        
 Leu Cys Glu Gly Asp Glu Val Val Ser Ile Asn Gly Asn Pro Cys Ala
          35                  40                  45            
 Asp Leu Thr Tyr Pro Glu Val Ile Lys Leu Met Glu Ser Ile Thr Asp
      50                  55                  60                
 Ser Leu Gln Met Leu Ile Lys Arg Pro Ser Ser Gly Ile Ser Glu Ala
  65                  70                  75                  80
 Leu Ile Ser Glu Asn Glu Asn Lys Asn Leu Glu His Leu Thr His Gly
                  85                  90                  95    
 Gly Tyr Val Glu Ser Thr Thr Leu Gln Ile Arg Pro Ala Thr Lys Thr
             100                 105                 110        
 Gln Cys Thr Glu Phe Phe Leu Ala Pro Val Lys Thr Glu Val Pro Leu
         115                 120                 125            
 Ala Glu Asn Gln Arg Ser Gly Pro Asp Cys Ala Gly Ser Leu Lys Glu
     130                 135                 140                
 Glu Thr Gly Pro Ser Tyr Gln Arg Ala Pro Gln Met Pro Asp Ser Gln
 145                 150                 155                 160
 Arg Gly Arg Val Ala Glu Glu Leu Ile Leu Arg Glu Lys Val Glu Ala
                 165                 170                 175    
 Val Gln Pro Gly Pro Val Val Glu Leu Gln Leu Ser Leu Ser Gln Glu
             180                 185                 190        
 Arg His Lys Gly Ala Ser Gly Pro Leu Val Ala Leu Pro Gly Ala Glu
         195                 200                 205            
 Lys Ser Lys Ser Pro Asp Pro Asp Pro Asn Leu Ser His Asp Arg Ile
     210                 215                 220                
 Val His Ile Asn Ser Ile Pro Thr Asn Glu Lys Ala Asp Pro Phe Leu
 225                 230                 235                 240
 Arg Ser Ser Lys Ile Ile Gln Ile Ser Ser Gly Arg Glu Leu Arg Val
                 245                 250                 255    
 Ile Gln Glu Ser Glu Ala Gly Asp Ala Gly Leu Pro Arg Val Glu Val
             260                 265                 270        
 Ile Leu Asp Cys Ser Asp Arg Gln Lys Thr Glu Gly Cys Arg Leu Gln
         275                 280                 285            
 Ala Gly Lys Glu Cys Val Asp Ser Pro Val Glu Gly Gly Gln Ser Glu
     290                 295                 300                
 Ala Pro Pro Ser Leu Val Ser Phe Ala Val Ser Ser Glu Gly Thr Glu
 305                 310                 315                 320
 Gln Gly Glu Asp Pro Arg Ser Glu Lys Asp His Ser Arg Pro His Lys
                 325                 330                 335    
 His Arg Ala Arg His Ala Arg Lys Phe Cys Leu Gly Phe Gln Lys Gly
             340                 345                 350        
 Leu Gly Ser Trp Gly His Phe Ala Ala Ser Leu Leu Ala
         355                 360                 365



      <210> 1289
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 1289
 Met Ala Val Leu Pro Glu Asp Pro Ala Ala Glu Phe His Leu Ile Leu
   1               5                  10                  15    
 Ile Ser Leu Ser Pro Leu Leu Ser Leu Gly Leu Val Phe Ala Thr Ile
              20                  25                  30        
 Pro Val Ser Ala Lys Trp Gly Leu Glu Val Ile Asn Ser Asn Trp Cys
          35                  40                  45            
 Met Gly Cys Ala Pro Glu Leu Gly Cys Ser Gln Thr Lys Leu Ser Val
      50                  55                  60                
 Tyr Met Glu Cys Leu Glu Gly Ile Cys His Glu Ser Val Ala Asn Cys
  65                  70                  75                  80
 Thr Asn Gln Glu Ser Trp Leu Val Gly Glu Lys Thr Leu Thr Leu Thr
                  85                  90                  95    
 Leu Leu Ser Gln Leu Leu Val Gln Ile Met Pro Tyr Thr Tyr Ser Val
             100                 105                 110        
 Tyr Thr Leu Leu Ser Cys Ser Glu Gly Ser Gln Cys Ser Ser Ala Val
         115                 120                 125            
 Arg Ala Glu Ser His Phe
     130                



      <210> 1290
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1290
 Met Glu Tyr Val Leu Asn Ser Ser Thr Trp Arg Thr Phe Leu Glu Ala
   1               5                  10                  15    
 Leu Tyr Thr Ser Trp Leu Tyr Leu Leu Gln Val Pro Pro Ala Cys Ala
              20                  25                  30        
 Leu Cys Ser Ser Cys Ala Asn Asn Leu Arg Glu Thr Cys Ala Glu Ala
          35                  40                  45            
 His Leu His Thr Cys Ala Trp
      50                  55



      <210> 1291
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1291
 Met Pro Ser Leu Tyr Ala Phe Ile Ile Met Val Leu Thr Thr Ile Thr
   1               5                  10                  15    
 Leu Leu Cys Thr Ser Val Ile Thr Leu Pro Val Ser Ser Thr Pro Val
              20                  25                  30        
 Thr Arg Ala Ser Gln Ser Pro Asn Pro Thr Ala Lys Ala Leu Thr Ala
          35                  40                  45            
 Gly Leu Cys Gly Ser Ser Ser Gln Val His Gly Gln Lys Ala Ala Trp
      50                  55                  60                
 Glu Asp Pro Val Glu Trp Val Arg Asp Thr Leu Pro Trp Pro Ser Ala
  65                  70                  75                  80
 Gln Gln Asp Gln Ser Lys Leu Tyr His Leu Pro Pro Pro Thr Val Gly
                  85                  90                  95    
 Pro His Ser Ile Ala Ser Pro Pro Glu Asp Arg Thr Val Lys Asp Ser
             100                 105                 110        
 Thr Pro Ser Ser Leu Asp Ser Asp Pro Leu Met Ala Met Leu Leu Lys
         115                 120                 125            
 Leu Gln Glu Ala Ala Asn Tyr Ile Glu Ser Pro Asp Arg Glu Thr Ile
     130                 135                 140                
 Leu Asp Pro Asn Leu Gln Ala Thr Leu
 145                 150            



      <210> 1292
      <211> 92
      <212> PRT
      <213> Homo sapiens


      <400> 1292
 Met Thr Ser Val Ser Thr Gln Leu Ser Leu Val Leu Met Ser Leu Leu
   1               5                  10                  15    
 Leu Val Leu Pro Val Val Glu Ala Val Glu Ala Gly Asp Ala Val Ala
              20                  25                  30        
 Leu Leu Leu Gly Val Val Leu Ser Ile Thr Gly Ile Cys Ala Ala Arg
          35                  40                  45            
 Glu Tyr Met His Glu Lys Glu Met Asp Arg Phe Tyr Gln Arg Val Ala
      50                  55                  60                
 Phe Asn Val Ile Asp Gln Leu Ala Val Thr Cys Asn Val Pro Phe His
  65                  70                  75                  80
 Trp Glu Gln Cys Met Phe Gln Lys Glu Arg Gly Ile
                  85                  90        



      <210> 1293
      <211> 73
      <212> PRT
      <213> Homo sapiens


      <400> 1293
 Met Pro Trp Ala Pro Ser Val Cys Leu Arg Leu Cys Gly Ile Pro Ala
   1               5                  10                  15    
 Leu Thr Leu Gly Thr Cys Ala Pro Ser Lys Pro Thr Trp His Thr Arg
              20                  25                  30        
 Arg Glu Gly Leu Ser His Leu His Thr Val Arg Pro Phe Ser Val Leu
          35                  40                  45            
 Val Gly Ser His Gly Gln Gln Gln Lys Leu Leu Ser Pro Phe Val Thr
      50                  55                  60                
 Ser Glu Arg Leu Pro Thr Cys Ile Phe
  65                  70            



      <210> 1294
      <211> 81
      <212> PRT
      <213> Homo sapiens


      <400> 1294
 Met Thr Ile His Ile Leu Ile Leu Leu Leu Leu Leu Ala Phe Ser Ala
   1               5                  10                  15    
 Gln Gly Asp Leu Asp Thr Ala Ala Arg Arg Gly Gln His Gln Val Pro
              20                  25                  30        
 Gln His Arg Gly His Val Cys Tyr Leu Gly Glu Pro Ser Gly Lys Ala
          35                  40                  45            
 Ser His Glu Pro Gln Asp Pro Tyr Ser Tyr Gly Arg Arg Arg Trp Arg
      50                  55                  60                
 Glu Ala Glu Ala Arg Leu Gly Ser Gln Asp Ser Gly Leu Gln Arg Gly
  65                  70                  75                  80
 Gly
    



      <210> 1295
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 1295
 Met Arg Ala Ala Arg Arg Leu Pro Phe Phe Met Ala Arg Ala Trp Tyr
   1               5                  10                  15    
 His Leu Pro Arg Gly Ala Glu Pro Ala Ile Ser Asp Cys Ala Ser His
              20                  25                  30        
 Val Cys Gly Phe Leu Gly Pro Thr Ala Gly Asp Asn Gly Arg Ser Gly
          35                  40                  45            
 Leu Gly Glu Pro Arg Leu Ser Pro Gly Val Leu Ala Gly Ser
      50                  55                  60        



      <210> 1296
      <211> 258
      <212> PRT
      <213> Homo sapiens


      <400> 1296
 Met Ala Gly Ala Val Ser Leu Leu Gly Val Val Gly Leu Leu Leu Val
   1               5                  10                  15    
 Ser Ala Leu Ser Gly Val Leu Gly Asp Arg Ala Asn Pro Asp Leu Arg
              20                  25                  30        
 Ala His Pro Gly Asn Ala Ala His Pro Gly Ser Gly Ala Thr Glu Pro
          35                  40                  45            
 Arg Arg Arg Pro Pro Leu Lys Asp Gln Arg Glu Arg Thr Arg Ala Gly
      50                  55                  60                
 Ser Leu Pro Leu Gly Ala Leu Tyr Thr Ala Ala Val Ala Ala Phe Val
  65                  70                  75                  80
 Leu Tyr Lys Cys Leu Gln Gly Lys Asp Glu Thr Ala Val Leu His Glu
                  85                  90                  95    
 Glu Ala Ser Lys Gln Gln Pro Leu Gln Ser Glu Gln Gln Leu Ala Gln
             100                 105                 110        
 Leu Thr Gln Gln Leu Ala Gln Thr Glu Gln His Leu Asn Asn Leu Met
         115                 120                 125            
 Ala Gln Leu Asp Pro Leu Phe Glu Arg Val Thr Thr Leu Ala Gly Ala
     130                 135                 140                
 Gln Gln Glu Leu Leu Asn Met Lys Leu Trp Thr Ile His Glu Leu Leu
 145                 150                 155                 160
 Gln Asp Ser Lys Pro Asp Lys Asp Met Glu Ala Ser Glu Pro Gly Glu
                 165                 170                 175    
 Gly Ser Gly Gly Glu Ser Ala Gly Gly Gly Asp Lys Val Ser Glu Thr
             180                 185                 190        
 Gly Thr Phe Leu Ile Ser Pro His Thr Glu Ala Ser Arg Pro Leu Pro
         195                 200                 205            
 Glu Asp Phe Cys Leu Lys Glu Asp Glu Glu Glu Ile Gly Asp Ser Gln
     210                 215                 220                
 Ala Trp Glu Glu Pro Thr Asn Trp Ser Thr Glu Thr Trp Asn Leu Ala
 225                 230                 235                 240
 Thr Ser Trp Glu Val Pro Lys Asp Asn Trp Ala Phe Leu Lys Ser Cys
                 245                 250                 255    
 Pro Tyr
        



      <210> 1297
      <211> 53
      <212> PRT
      <213> Homo sapiens


      <400> 1297
 Met Ala Phe Phe Phe Ile Arg Thr Leu Val Phe Ala Glu Glu Leu Phe
   1               5                  10                  15    
 Gln Lys Pro Tyr Arg Ala Met Val Gly Leu Gln Leu Phe Thr Asn Ala
              20                  25                  30        
 Phe His Ser Phe Met Pro Lys Asn Met Tyr Gly Thr Arg Ile Lys Lys
          35                  40                  45            
 Lys Arg Leu Pro Glu
      50            



      <210> 1298
      <211> 459
      <212> PRT
      <213> Homo sapiens


      <400> 1298
 Met Ala Thr Asp Gln Leu Met Val Lys Trp Lys Leu Gly Leu Gln Ala
   1               5                  10                  15    
 Leu Leu Gly Leu Arg Ile Leu Pro Ala Asp Thr Gln Ala Glu Glu Cys
              20                  25                  30        
 Glu Leu Ser Ala Pro Lys Lys Gln Leu Arg Thr Phe His Ser Lys Ser
          35                  40                  45            
 Lys Gln Gln Lys Ser Ala Gln Arg Val Glu Arg Lys Pro Pro Arg Leu
      50                  55                  60                
 Glu Gly Glu Ala Asp Thr Arg Thr Val Lys Asp Asp Thr Ala Glu Glu
  65                  70                  75                  80
 Trp Ala Ala Gly Gly Met Leu Trp Leu Glu Gln Ser Glu Ser Leu Phe
                  85                  90                  95    
 Glu Glu Val Glu Phe Lys Pro Gly Phe Val Tyr Arg Lys Val Leu Arg
             100                 105                 110        
 Ala Lys Gly Val Val Lys Lys Cys Val Ser Arg Thr Gln Ala Leu Val
         115                 120                 125            
 Gly Phe Ser Tyr Gly Asp Thr Lys Val Val Ser Thr Ser Phe Ile Thr
     130                 135                 140                
 Pro Val Gly Gly Ala Met Pro Cys Pro Leu Leu Gln Val Gly Asp Tyr
 145                 150                 155                 160
 Val Phe Ala Lys Ile Val Ile Pro Lys Gly Phe Asp Phe Tyr Val Pro
                 165                 170                 175    
 Ala Ile Val Ile Ala Leu Pro Asn Lys His Val Ala Thr Glu Lys Phe
             180                 185                 190        
 Tyr Thr Val Leu Lys Cys Asn Asn Arg Arg Gly Val Cys Pro Gln Asp
         195                 200                 205            
 Pro Ser Val Ala Pro Ala Gly Ser Met Ser Leu Thr Ser Ser Gln Val
     210                 215                 220                
 Glu Asp Ser Leu Leu Pro Glu Cys Gly Leu Cys Ala Phe Thr Arg Leu
 225                 230                 235                 240
 Ser Ile Leu Pro Gly Gln Leu Phe Leu Ala Leu Ser His Leu Gly Asn
                 245                 250                 255    
 Ser Lys Thr Glu Leu Lys Arg Gln His His His Val Met Ser Gln His
             260                 265                 270        
 Pro Ser Pro Pro Arg Thr Gly Pro Tyr Thr Gln Val Leu Arg Ala Val
         275                 280                 285            
 Gly Gly Ser Gln Thr Pro Lys Ala Arg Gly Asn Glu Leu Ser Gly Pro
     290                 295                 300                
 Lys Pro Ser Leu Lys His Trp Val His Ser Ala Pro Glu Thr Pro Phe
 305                 310                 315                 320
 His Gly Lys Arg Asp Val Gly Lys Glu Leu Arg Ser Ser Arg Gly Asp
                 325                 330                 335    
 Gly Leu Asp Ile Ser Val Asp Pro Ala Ala Ile Lys Ala Gly Glu Asp
             340                 345                 350        
 Val Glu Ala Arg Asn Ser Ala Phe Leu Phe Trp Pro Leu Lys Glu Ala
         355                 360                 365            
 Asp Thr Gln Asp Ser Arg Glu Pro Arg Arg Glu Lys Pro Arg Arg Lys
     370                 375                 380                
 Lys Arg Pro Ala Lys Gln Pro Leu Gln Gln Ala Ala Pro Ser Asp Ser
 385                 390                 395                 400
 Asp Gly Ser Ser His Gly Ile Ser Ser His Gly Ser Cys Gln Gly Thr
                 405                 410                 415    
 His Pro Glu Pro Arg Cys Thr Arg Pro Ser Phe Asp Val Phe Asn Asp
             420                 425                 430        
 Ser Ala Tyr Phe Ser Val Met Glu Glu Val Ala Ile Thr Thr Val Asn
         435                 440                 445            
 Phe His Leu Gln Pro Ile Gln Asn Gly Ser Asn
     450                 455                



      <210> 1299
      <211> 285
      <212> PRT
      <213> Homo sapiens


      <400> 1299
 Met Ala Arg Arg Gly Val Ala Ser Phe Leu Thr Ser Phe Leu Ser Gly
   1               5                  10                  15    
 Val Pro Ala Glu Ala Leu Gln Pro Pro Val Thr Val Gln Ser Pro Pro
              20                  25                  30        
 Ala Gly Gly Ser Pro Arg Asp Arg Cys Leu Ser Gly Ser His Leu Glu
          35                  40                  45            
 Glu Pro Glu Leu Gln Pro Gly Ala Ala Arg Gly Gly Gln Pro Ser Pro
      50                  55                  60                
 Leu Ser Thr His Ser Ser Gln Leu His Leu Arg Ala Pro Ala Leu Thr
  65                  70                  75                  80
 Val Glu Asp Leu Arg Ala Gln Ala Ser Leu Ser Lys Asp Ser Pro Trp
                  85                  90                  95    
 Gly Pro Trp Leu Pro Glu Leu Leu Gly Cys Leu Gly Pro Pro Leu Thr
             100                 105                 110        
 Leu Gln Cys Arg Glu Gly Cys Thr Pro Lys Pro Ala Val Pro Thr Val
         115                 120                 125            
 Ser Leu Ala Glu Gly Trp Gly Glu Ile Ala Glu Glu Ala Pro Gly Gly
     130                 135                 140                
 Lys Arg Ala Lys Asp Arg Thr Tyr Gly Glu Thr Ser Arg Gly Gly Ser
 145                 150                 155                 160
 Glu Pro Gln Pro Pro Gly Glu Arg Glu Asn Val Ser Glu Ala Met Lys
                 165                 170                 175    
 Arg Pro Phe Pro Asp Ala Ala Glu Gly Ala Glu Glu Glu Pro Pro Pro
             180                 185                 190        
 Ser Ala Gly Gln Arg Glu Gly Asp Val Thr Phe Glu Asn Ser Ala Ser
         195                 200                 205            
 Pro Ala Gln Pro Gly Glu Lys Leu Ala Pro Lys Gly Phe Leu Gln Arg
     210                 215                 220                
 Leu Val Gln Ala Pro Glu Gly Ser Ala Asp Trp Thr Arg Phe Pro Ala
 225                 230                 235                 240
 Trp Ser Lys Ala Ala Asp Ala Pro Ser Phe Leu Trp Leu Leu Arg Leu
                 245                 250                 255    
 Ser Pro Leu Ala Pro Gln Met Ala Lys Lys His Met Lys Arg Cys Ser
             260                 265                 270        
 Pro Ser Leu Val Ile Arg Asp Cys Lys Ser Asn Leu Gln
         275                 280                 285



      <210> 1300
      <211> 181
      <212> PRT
      <213> Homo sapiens


      <400> 1300
 Met Leu Phe Arg Asn Arg Phe Leu Leu Leu Leu Ala Leu Ala Ala Leu
   1               5                  10                  15    
 Leu Ala Phe Val Ser Leu Ser Leu Gln Phe Trp Ser Ser Leu Ser Ser
              20                  25                  30        
 Gly Glu Glu Ser Gln Ala Asp Thr Leu Glu Tyr Gln Val Leu Cys Ala
          35                  40                  45            
 Gly Thr Gly Pro Phe Pro Ala Phe Leu Leu Glu Pro Gly Leu His Ile
      50                  55                  60                
 Asp Pro Val His Leu Ile Pro Val Ser Thr Pro Lys Asn Gly Met Ser
  65                  70                  75                  80
 Ser Lys Ser Arg Lys Arg Ile Met Pro Asp Pro Val Thr Glu Pro Pro
                  85                  90                  95    
 Val Thr Asp Pro Val Tyr Glu Ala Leu Leu Tyr Cys Asn Ile Pro Ser
             100                 105                 110        
 Val Ala Glu Arg Ser Met Glu Gly His Ala Pro His His Phe Lys Leu
         115                 120                 125            
 Val Ser Val His Val Phe Ile Arg His Gly Asp Arg Tyr Pro Leu Tyr
     130                 135                 140                
 Val Ile Pro Lys Thr Lys Arg Pro Glu Ile Asp Cys Thr Leu Val Ala
 145                 150                 155                 160
 Asn Arg Ala Pro Val Thr Val Met Pro Gly Pro Ser Asn Gly Ala Ile
                 165                 170                 175    
 Phe Gly Ala Pro Ile
             180    



      <210> 1301
      <211> 483
      <212> PRT
      <213> Homo sapiens


      <400> 1301
 Met His Val Leu Leu Ala Leu Ser Gly Arg Gly Cys Leu Val Leu Arg
   1               5                  10                  15    
 His Val Val Met Gly Ser His Ser Pro Cys Ala His Thr Pro Cys Ala
              20                  25                  30        
 Pro Pro Ala Pro Thr Gly Ala Lys Arg Thr Leu Ala Ala Ser Gly Ser
          35                  40                  45            
 Gln Ser Ser Asn Gly Pro Glu Pro Gly Gly Gln Gln Leu Lys Thr Arg
      50                  55                  60                
 Thr Leu Ser Gly Met Ala Ser Lys Thr Thr Thr Thr Ile Ile Pro Lys
  65                  70                  75                  80
 Arg Ile Ala His Ser Pro Ser Leu Gln Ser Leu Lys Lys Pro Ile Ile
                  85                  90                  95    
 Pro Lys Glu Phe Gly Gly Lys Val Pro Thr Val Ile Arg Gln Arg Tyr
             100                 105                 110        
 Leu Asn Leu Phe Ile Glu Glu Cys Leu Lys Phe Cys Thr Ser Asn Gln
         115                 120                 125            
 Glu Ala Ile Glu Lys Ala Leu Asn Glu Glu Lys Val Ala Tyr Asp Arg
     130                 135                 140                
 Ser Pro Ser Lys Asn Ile Tyr Leu Asn Val Ala Val Asn Thr Leu Lys
 145                 150                 155                 160
 Lys Leu Arg Gly Leu Ala Pro Ser Ala Val Pro Gly Leu Ser Lys Thr
                 165                 170                 175    
 Ser Gly Arg Arg Val Val Ser His Glu Val Val Leu Gly Gly Arg Leu
             180                 185                 190        
 Ala Ala Lys Thr Ser Phe Ser Leu Ser Arg Pro Ser Ser Pro Arg Val
         195                 200                 205            
 Glu Asp Leu Lys Gly Ala Ala Leu Tyr Ser Arg Leu Arg Glu Tyr Leu
     210                 215                 220                
 Leu Thr Gln Asp Gln Leu Lys Glu Asn Gly Tyr Pro Phe Pro His Pro
 225                 230                 235                 240
 Glu Arg Pro Gly Gly Ala Ile Ile Phe Thr Ala Glu Glu Lys Arg Pro
                 245                 250                 255    
 Lys Asp Cys Glu Ser Leu Ala Cys Asp Gly Leu Val Ala Gly Gly Trp
             260                 265                 270        
 Glu Thr Gln Tyr Met Cys Cys Ser Ala Ala Ala Gly Ser Val Gly Cys
         275                 280                 285            
 Gln Val Ala Lys Gln His Val Gln Asp Gly Arg Lys Glu Arg Leu Glu
     290                 295                 300                
 Gly Phe Val Lys Thr Phe Glu Lys Glu Leu Ser Gly Asp Thr His Pro
 305                 310                 315                 320
 Gly Ile Tyr Ala Leu Asp Cys Glu Met Ser Tyr Thr Thr Tyr Gly Leu
                 325                 330                 335    
 Glu Leu Thr Arg Val Thr Val Val Asp Thr Asp Val His Val Val Tyr
             340                 345                 350        
 Asp Thr Phe Val Lys Pro Asp Asn Glu Ile Val Asp Tyr Asn Thr Arg
         355                 360                 365            
 Phe Ser Gly Val Thr Glu Ala Asp Leu Ala Asp Thr Ser Val Thr Leu
     370                 375                 380                
 Arg Asp Val Gln Ala Val Leu Leu Ser Met Phe Ser Ala Asp Thr Ile
 385                 390                 395                 400
 Leu Ile Gly His Ser Leu Glu Ser Asp Leu Leu Ala Leu Lys Val Ile
                 405                 410                 415    
 His Ser Thr Val Val Asp Thr Ser Val Leu Phe Pro His Arg Leu Gly
             420                 425                 430        
 Leu Pro Tyr Lys Arg Ser Leu Arg Asn Leu Met Ala Asp Tyr Leu Arg
         435                 440                 445            
 Gln Ile Ile Gln Asp Asn Val Asp Gly His Ser Ser Ser Glu Asp Ala
     450                 455                 460                
 Gly Ala Cys Met His Leu Val Ile Trp Lys Val Arg Glu Asp Ala Lys
 465                 470                 475                 480
 Thr Lys Arg
            



      <210> 1302
      <211> 405
      <212> PRT
      <213> Homo sapiens


      <400> 1302
 Met Lys Ala Gly Thr Ile Ser Ile Ile Leu Ser Thr Trp Leu Val Leu
   1               5                  10                  15    
 Cys Leu Thr Gln Ile Ile Val Asn Ile Ile His Asn Thr Ser Asp Tyr
              20                  25                  30        
 His Pro Lys Val Leu Arg Phe Leu Asn Val Ala Phe Asp Gly Thr Gly
          35                  40                  45            
 Asp Cys Leu Ile Ala Gly Asp His Gln Gly Asn Ile Tyr Val Phe Asp
      50                  55                  60                
 Leu His Gly Asn Ser Leu Lys Tyr Ile Val Leu Val Ile Leu Met Asp
  65                  70                  75                  80
 Val Phe Thr Asp Val Glu Ile Phe Cys Asp Ile Leu Glu Ala Ala Asn
                  85                  90                  95    
 Lys Arg Gly Val Phe Val Cys Val Leu Leu Asp Gln Gly Gly Val Lys
             100                 105                 110        
 Leu Phe Gln Glu Met Cys Asp Lys Val Gln Ile Ser Asp Ser His Leu
         115                 120                 125            
 Lys Asn Ile Ser Ile Arg Ser Val Glu Gly Glu Ile Tyr Cys Ala Lys
     130                 135                 140                
 Ser Gly Arg Lys Phe Ala Gly Gln Ile Arg Glu Lys Phe Ile Ile Ser
 145                 150                 155                 160
 Asp Trp Arg Phe Val Leu Ser Gly Ser Tyr Arg Ile His Gly Glu Gln
                 165                 170                 175    
 Gly Leu Ser Glu Val Gln Thr Ser Ser Arg Cys Ser Asp Thr Asn Thr
             180                 185                 190        
 Pro Ser Ser Ser Gln Lys Val Ser Leu Cys Pro Glu Leu Glu Leu His
         195                 200                 205            
 His Ile Asp Gly Val Arg Gly Lys Lys Cys Gly Pro Phe Leu Ala Arg
     210                 215                 220                
 Ile Pro Ala Gly Ser Phe Thr Trp Leu Cys Gly His Val His Arg Asn
 225                 230                 235                 240
 Ile Leu Ser Lys Phe Thr Gly Gln Ala Val Glu Leu Phe Asp Glu Glu
                 245                 250                 255    
 Phe Arg His Leu Tyr Ala Ser Ser Lys Pro Val Met Gly Leu Lys Ser
             260                 265                 270        
 Pro Arg Leu Val Ala Pro Val Pro Pro Gly Ala Ala Pro Ala Asn Gly
         275                 280                 285            
 Arg Leu Ser Ser Ser Ser Gly Ser Ala Ser Asp Arg Thr Ser Ser Asn
     290                 295                 300                
 Pro Phe Ser Gly Arg Ser Ala Gly Ser His Pro Gly Thr Arg Ser Val
 305                 310                 315                 320
 Ser Ala Ser Ser Gly Pro Cys Ser Pro Ala Ala Pro His Pro Pro Pro
                 325                 330                 335    
 Pro Pro Arg Phe Gln Pro His Gln Gly Pro Trp Gly Ala Pro Ser Pro
             340                 345                 350        
 Gln Ala His Leu Ser Pro Arg Pro His Asp Gly Pro Pro Ala Ala Val
         355                 360                 365            
 Tyr Ser Asn Leu Gly Ala Tyr Arg Pro Thr Arg Leu Gln Leu Glu Gln
     370                 375                 380                
 Leu Gly Leu Val Pro Arg Leu Thr Pro Thr Trp Arg Pro Phe Leu Gln
 385                 390                 395                 400
 Ala Ser Pro His Phe
                 405



      <210> 1303
      <211> 387
      <212> PRT
      <213> Homo sapiens


      <400> 1303
 Met Ser His Cys Ala Arg Pro Tyr Leu Val Leu Leu Pro Val Asn Phe
   1               5                  10                  15    
 Leu Phe Leu Ala Phe Phe Ile Leu Ser Pro Leu Thr Gln Asp Leu Ala
              20                  25                  30        
 Gln Ile Met Met Ile Asn Lys Val Gly Ile Asn Val Thr Tyr Ile Lys
          35                  40                  45            
 Glu Arg Ile Leu Asp Pro Ser Pro Gly Gly Val Pro Lys Met Pro Pro
      50                  55                  60                
 Ala Trp Ser Gly Glu Ser Met Asp Arg Gly Val Val Gly Leu Gly Ser
  65                  70                  75                  80
 Thr Lys Thr Gln Arg Gly Ala Arg Ala Pro Pro Pro Gln Thr Ala Glu
                  85                  90                  95    
 Gly Arg Glu Gly Ala Pro Gly Ala Val Val Ala Met Ala Pro Asp Cys
             100                 105                 110        
 Phe Lys His Asp Phe Phe Arg Tyr Thr Ile Phe Asp Ser Ser Glu Lys
         115                 120                 125            
 Thr Arg Asp Ala Ser Ala Val Ile Leu Gln Gly Gly Lys Gln Arg Thr
     130                 135                 140                
 Ser Thr Ser Arg Arg Gly Pro Leu Ala Ser Gly Ser Leu Ser Ile Phe
 145                 150                 155                 160
 Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys
                 165                 170                 175    
 Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro
             180                 185                 190        
 Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg
         195                 200                 205            
 Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser
     210                 215                 220                
 Thr Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr
 225                 230                 235                 240
 Gln Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln
                 245                 250                 255    
 Tyr Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr
             260                 265                 270        
 Ser Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser
         275                 280                 285            
 Gln Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln
     290                 295                 300                
 Gly Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly
 305                 310                 315                 320
 Arg Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg
                 325                 330                 335    
 Ile His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile
             340                 345                 350        
 His Thr Phe Lys Pro Arg Ser Thr Gln Tyr Leu Gln Gly Arg Ile His
         355                 360                 365            
 Thr Phe Lys Pro Arg Ser Thr Gln Tyr Ser Gln Gly Arg Ile His Thr
     370                 375                 380                
 Phe Lys Cys
 385        



      <210> 1304
      <211> 383
      <212> PRT
      <213> Homo sapiens


      <400> 1304
 Met Val Val Cys Gln Leu Ser Thr Val Trp Ile Leu Asp Trp Ala Gln
   1               5                  10                  15    
 Gln Gln Thr Gly Ser Asp Ser Lys Ser Val Glu Ile Met Gly Glu Ala
              20                  25                  30        
 Ala Ile Arg Phe Arg Ser Ala Glu Lys Val Gln Cys Ala Pro Thr Ser
          35                  40                  45            
 Pro Thr Val His Gln Val Leu Glu Ser Arg Pro Cys Pro Ile Gly Pro
      50                  55                  60                
 Thr Trp Ala Ser Tyr Ser Cys Ser Pro Ala Cys Pro Ala Phe Leu Gly
  65                  70                  75                  80
 Lys Pro Trp Ser Gly Glu Gly Gly Val Gln Leu Pro Asp Pro Gly Ser
                  85                  90                  95    
 Gly Phe Thr Pro Leu Gly Phe Gly Ile Cys His Arg Glu Ser Arg Lys
             100                 105                 110        
 Gly Pro Val Gln Leu Pro Ser Thr Arg Lys Glu Lys Asp Glu Gln Thr
         115                 120                 125            
 Glu Asn Gln Gln Leu Phe Phe Ile Arg Gln Arg Thr Glu Ser Pro Gly
     130                 135                 140                
 Lys Ala Arg Pro Pro Asn Leu Glu Thr Gln Thr Ser Gly Phe Gln Glu
 145                 150                 155                 160
 Pro Gln Leu Thr Gly Ala Glu Pro Leu Arg Gly Gln Cys His Gly Leu
                 165                 170                 175    
 Glu Leu Pro Leu Met Asn Phe Trp Arg Cys His Leu Asp Asn Leu Gln
             180                 185                 190        
 Ala Glu Ala Ala Ala Asp Gly Glu Ser Leu Val Cys Ser Cys Tyr Gln
         195                 200                 205            
 Leu Pro Glu Thr Leu Glu Gly Arg Ala Leu Leu Trp Gln Asp Thr Trp
     210                 215                 220                
 Gly Asp Gly Leu Gly Gly Glu Ile Pro Glu Val Gln Gly Ala Ser Phe
 225                 230                 235                 240
 Arg Gly Trp Lys Glu Val Thr Ser Leu Phe Asn Lys Asp Asp Glu Gln
                 245                 250                 255    
 His Leu Leu Glu Arg Cys Lys Ser Pro Lys Ser Lys Gly Thr Asn Leu
             260                 265                 270        
 Arg Leu Lys Glu Glu Leu Lys Ala Glu Lys Lys Ser Gly Phe Trp Asp
         275                 280                 285            
 Asn Leu Val Leu Lys Gln Asn Ile Gln Ser Lys Lys Pro Asp Glu Ile
     290                 295                 300                
 Glu Gly Trp Glu Pro Pro Lys Leu Ala Leu Glu Asp Ile Ser Ala Asp
 305                 310                 315                 320
 Pro Glu Asp Thr Val Gly Gly His Pro Ser Trp Ser Gly Trp Glu Asp
                 325                 330                 335    
 Asp Ala Lys Gly Ser Thr Lys Tyr Thr Ser Leu Ala Ser Ser Ala Asn
             340                 345                 350        
 Ser Ser Arg Trp Ser Leu Arg Ala Ala Gly Arg Leu Val Ser Ile Arg
         355                 360                 365            
 Arg Gln Ser Lys Gly His Leu Thr Asp Ser Pro Glu Glu Ala Glu
     370                 375                 380            



      <210> 1305
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 1305
 Met Leu Leu Ala Ser Leu Trp Gly Leu Ser Cys Lys Trp Cys Cys Val
   1               5                  10                  15    
 Arg Ala Lys Glu Arg Gln His Ile Thr Glu Leu Gln Thr Pro Glu His
              20                  25                  30        
 Ser Glu Pro Glu Gly Ile Gly His Leu Gln Ala Ala Thr Glu Ala Val
          35                  40                  45            
 Leu Pro His Ser Thr Gln Asn Leu Ile Thr Lys Arg Asn Leu Met Val
      50                  55                  60                
 Gln Val Thr Gln Ser Phe Lys Val Ala Phe Phe His Gly
  65                  70                  75        



      <210> 1306
      <211> 303
      <212> PRT
      <213> Homo sapiens


      <400> 1306
 Met Ala Val Val Ala Val Thr Val Ala Val Ala Val Ala Val Ala Met
   1               5                  10                  15    
 Ser Val Val Val Ala Val Ala Val Ala Gly Gly Trp Val Ala Met Ala
              20                  25                  30        
 Ala Ala Val Ala Val Val Val Ser Thr Ala Gly Val Val Ala Glu Val
          35                  40                  45            
 Ser Thr Ile Pro Ser Pro Pro His Arg Ser Ala Leu Ser Pro Pro Leu
      50                  55                  60                
 Pro Leu Pro Thr Gly Gln His Tyr Pro Leu Pro Leu Pro Thr Val Glu
  65                  70                  75                  80
 Gly Ala Pro Gly Gln Arg Cys Asp Gln His Val Met Gly His Gly Leu
                  85                  90                  95    
 Leu Thr Ala Ser Gly Leu Gly Leu Ser Arg Val Gly Pro Pro Ala Val
             100                 105                 110        
 Gln Cys Gly Lys Val Gly Thr Ser Ile Leu Thr Ala Val Gly Ala Arg
         115                 120                 125            
 Pro Gly Ser Asp Lys Leu Phe Leu Ser Gly His Lys Arg Thr Gln Thr
     130                 135                 140                
 Leu Glu Leu Lys Glu Thr Phe Gly Pro Lys Ser Cys Lys Gly Ser Phe
 145                 150                 155                 160
 Glu Cys Lys Asp Leu Gly Thr Thr Pro Asp Arg Leu His Pro Ala Gln
                 165                 170                 175    
 Arg Gly Glu Thr Gln Arg Pro Gln Pro Leu Arg Thr Arg Ala Ser Gly
             180                 185                 190        
 Ser Arg Gly Ser Arg Ser Val Leu Gln Ser Ile Ser Ala Gly Phe Ser
         195                 200                 205            
 Pro Ala Thr Val Ser Leu Phe Ser Ser Pro Pro Ser Pro Ser Pro Pro
     210                 215                 220                
 Pro Pro Thr Pro Gln Leu Glu Gln Asn Asn Asn Arg Ala Leu Ala Ser
 225                 230                 235                 240
 Arg Arg Asn Cys Thr Asp Ile Ser Arg Thr Glu Ala Met Ser Ser Arg
                 245                 250                 255    
 Arg Pro Ser Asn Trp Gly Ser Arg Ala Arg Arg Arg Ser Gln Leu Asn
             260                 265                 270        
 Asp Ile Arg Phe Leu Val Pro Val Lys Lys Gln Ile Pro Leu Gly Pro
         275                 280                 285            
 Pro Ala Leu Pro Glu Lys Gly Gln Gln Leu Leu Glu Pro Ala Arg
     290                 295                 300            



      <210> 1307
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1307
 Met Ala Arg Ser Val Gln Trp Met Gly Arg Thr Arg Phe Ile Pro Val
   1               5                  10                  15    
 Phe Gln Thr Ile Pro Ile Gly Ser Asn Ile Leu Leu Arg Lys Pro Tyr
              20                  25                  30        
 Ser Asp Leu Ala Gly Leu Trp Gln Ser Val Asn Leu Thr Phe Arg Phe
          35                  40                  45            
 Val Arg Gly Leu Gly Ser Asp Asn Pro Leu Val Thr Met Gln Arg Ser
      50                  55                  60                
 Phe Tyr Gly Ile Leu Phe Pro Lys Ala Ser Val Leu Phe Ala
  65                  70                  75            



      <210> 1308
      <211> 322
      <212> PRT
      <213> Homo sapiens


      <400> 1308
 Met Leu Ala Gly Ala Gly Thr Leu Cys Pro Trp Leu Ala Val Phe Ala
   1               5                  10                  15    
 Pro Leu Trp Trp Leu Gly Ala Pro Thr Leu Ser Ser Arg Ser Leu Cys
              20                  25                  30        
 Phe Cys Pro Gly Leu Ala Ser Ile Ser Thr Gln Ala Leu Ser Thr Leu
          35                  40                  45            
 Gln Leu Ala Leu Trp Pro Ser Gln Glu Pro Thr Val Val His Pro Leu
      50                  55                  60                
 Cys Gly Glu Pro Ser Cys Arg Pro Cys Thr Pro Ser Thr Asp Thr Asp
  65                  70                  75                  80
 His Lys Ala Ser Pro Arg Lys Ala Pro Glu Ser Asp Gln Asp Pro Pro
                  85                  90                  95    
 Arg Glu Pro Ala Lys Asn Thr Asp Ala Trp Leu Pro Pro Gly Ser Pro
             100                 105                 110        
 Asn Leu Ala His Ser Glu Asn Trp Pro Val Pro Leu Thr Asp Val Pro
         115                 120                 125            
 Lys Gly Leu Ser Val Val Glu Tyr Glu Asp Pro Gly Asp Gly Cys Trp
     130                 135                 140                
 Asp Ser Gln Arg Trp Thr Leu Thr Ala Ser Arg Gly Ala Lys Glu Gly
 145                 150                 155                 160
 Gln Cys Gly Val Cys Cys Lys Pro Gln Pro Thr Leu Leu Glu His Leu
                 165                 170                 175    
 Leu Tyr Thr Lys Arg Phe His Thr Val Lys Ala Arg Leu Gln Ala Met
             180                 185                 190        
 Ser Ser Ser Gln Thr Glu Thr Pro Arg Pro Pro Arg His Gln Gly Asp
         195                 200                 205            
 Ala Ala Thr Glu Ala Thr Arg Glu Ala Arg Gly His Leu Cys Gly Arg
     210                 215                 220                
 Pro Arg Ala Glu Asp Pro Gln Arg Cys Leu Pro Thr Ser Leu Ala Gln
 225                 230                 235                 240
 Cys Val Leu Tyr Pro Ala Tyr Pro Leu Ala Asn Val Leu Ser Gly Pro
                 245                 250                 255    
 Ala Trp Ser Arg Val Thr Gly Lys Trp Leu Trp Leu Asp Leu Asn Pro
             260                 265                 270        
 Gly Gln Pro Ser Lys Leu Ser Pro Asp Val Thr Ile Met Gln Val Lys
         275                 280                 285            
 Glu Val Leu Gly Lys Ile Lys Asp Tyr Leu Lys Arg Met Lys Ile Lys
     290                 295                 300                
 Leu Glu Asn Met Met Met Ser Arg Glu Gly Pro Gly Ala Pro Asp Arg
 305                 310                 315                 320
 Arg Pro
        



      <210> 1309
      <211> 274
      <212> PRT
      <213> Homo sapiens


      <400> 1309
 Met Arg Gly Ala Arg Gly Ala Trp Asp Phe Leu Cys Val Leu Leu Leu
   1               5                  10                  15    
 Leu Leu Arg Val Gln Thr Gly Gly Thr Pro Arg Leu Ala Pro Arg Pro
              20                  25                  30        
 Cys Asp Tyr Ser Ala Lys Pro Val Pro Gly Arg Val Val Pro Ala Arg
          35                  40                  45            
 Val His Pro Glu Arg Gly Leu Arg Ala Leu Ser Ala Arg Ala Phe Gln
      50                  55                  60                
 Pro Pro Gly Arg Leu Gln Val Ala Leu Gly Leu Ser Gly Ala Leu Pro
  65                  70                  75                  80
 Arg Ser Pro Ala Arg Gly Asp Pro Ser Cys Trp Trp Trp Gly Thr Arg
                  85                  90                  95    
 Ile Arg Gly Ser Ser Gly Met Gly Thr Ala Arg Gly Glu Leu Lys Val
             100                 105                 110        
 Met Ala Pro Val Asp Glu Ala Cys Ala Leu Gln Val Ala Leu Gly Ser
         115                 120                 125            
 Arg Ala Leu Ser Cys His Pro Leu Gly Ile Pro His Trp Ala Leu Asn
     130                 135                 140                
 Lys Met Ala Ile Leu Gly Ile Glu Glu Asp Ile Glu Leu Thr Lys Ala
 145                 150                 155                 160
 Leu Gly Asn Arg Ser Phe Glu Ser Asn Leu Lys Lys Leu Asp Leu Leu
                 165                 170                 175    
 Ser Leu Glu Lys Ile Ser Leu Tyr Ile Met Ala Phe Leu Ala Phe Trp
             180                 185                 190        
 Phe Ser Glu Thr His Pro Leu Ile Asp Ala Leu Trp Glu Val Val Pro
         195                 200                 205            
 Glu Leu Tyr Val His Asn Gly Glu Cys Val Val Cys Ile Phe Lys Gly
     210                 215                 220                
 Gln Gly Cys Val Glu Glu His Arg Leu Ser Arg Glu Asp Ile Cys Cys
 225                 230                 235                 240
 Phe Ser Leu Thr Thr Asn Gly Ser Ser Glu Asp Leu Thr Gly Leu Val
                 245                 250                 255    
 Trp Ala Val Asp Val Gly Ser Gly Leu Ser Asp Val Val His Gln Ile
             260                 265                 270        
 Glu Val
        



      <210> 1310
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1310
 Met Arg Pro Ala Val Arg Ala Ala Gly His Val Asp Ala Val Leu Ala
   1               5                  10                  15    
 Thr Ile Leu Leu Val Ala Leu Leu Ala Gln Ala Gly Asp Glu Val Val
              20                  25                  30        
 His Gln Ala Leu Asp Val Leu Leu Gln His Ala Gly Leu Val Gln Pro
          35                  40                  45            
 Arg Arg Ala Ala Leu Ile Ala Gln Leu Leu Glu Asp Ala His Ala His
      50                  55                  60                
 Arg Ala Arg Pro Leu Gly Ala Val Gln Glu His Val Glu Glu Asp Asp
  65                  70                  75                  80
 His Met Gly Arg Leu Pro Gly Tyr Gly Ile Glu Val Arg Pro Ser Leu
                  85                  90                  95    
 Ala Leu Thr Pro Glu Ser Leu Ile Thr
             100                 105



      <210> 1311
      <211> 270
      <212> PRT
      <213> Homo sapiens


      <400> 1311
 Met Asp Ser Ile Thr Leu Thr Thr Gln Asn Ile Phe Thr Ser Met Ile
   1               5                  10                  15    
 Ala Ile Ser Thr Pro Leu Ala Trp Val Gln Ser Thr Gln Pro Asn Lys
              20                  25                  30        
 Ser Ser Ala Val Ser Trp Ser Arg Val Gly Ala Gln Leu Arg Thr Pro
          35                  40                  45            
 Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Gly Thr Thr Gly Gln
      50                  55                  60                
 Cys Ser Asp Pro Gln Pro Asn Arg Arg Gly Ala Asp Pro Arg Gly Pro
  65                  70                  75                  80
 Thr Pro Leu Ser Leu Leu Pro Arg Arg Arg Arg Arg Gln Pro Ala Pro
                  85                  90                  95    
 Asp Pro Ser Val Ala Pro Pro Arg Trp Pro Pro Gly Pro Gly Asn Cys
             100                 105                 110        
 Gln Ile Gly Arg Tyr His Pro Arg Ala Cys Arg Gly Arg Ala Arg Arg
         115                 120                 125            
 Arg Arg Ala Phe Glu Ala Pro Ala Ala Asn Arg Val Thr Arg Asp Ser
     130                 135                 140                
 Trp Pro Gly Ala Gly Gly Gly Gly Gly Gly Arg Arg Ser Pro Arg Pro
 145                 150                 155                 160
 Glu Arg Pro Ala Ala Pro Thr Pro Ala Pro Leu His Pro Arg Gln Pro
                 165                 170                 175    
 Asp Gly Ser Leu Arg Gly Val His Trp Ser Lys Gln Val Pro Leu Arg
             180                 185                 190        
 Ala Arg Ala Leu Trp Glu Val Leu Gln Val Trp Arg Pro Gly Val Ser
         195                 200                 205            
 Ser Gly Arg Cys Trp Pro Asp Cys Pro Arg Cys Phe Pro Gly Ser Leu
     210                 215                 220                
 Ile Ser Ser Pro Gly Ser Thr His Leu Pro Gln Ser Lys His Gln Leu
 225                 230                 235                 240
 Thr Ile Thr Thr Arg Phe Thr Cys Arg Leu Pro Pro Thr Ile Ile Thr
                 245                 250                 255    
 Pro Leu Asn Gly Pro Cys Asp Tyr Leu Gln Glu Ser Gly Ile
             260                 265                 270



      <210> 1312
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1312
 Met Ala Arg Cys Val Ile Ile Tyr Trp Phe Trp Ala Val Ala Ser Gly
   1               5                  10                  15    
 Leu Val Gly Trp Ser Gly Thr Trp Lys Lys His Asp Trp Lys Ile Gly
              20                  25                  30        
 Asp Lys Glu Ile Arg Gly Arg Gly Met Trp Met Asp Leu Ser Glu Trp
          35                  40                  45            
 Ser Lys Thr Val Lys Ile Phe Val Ser Leu Val Ser Val His Gln Arg
      50                  55                  60                
 Val Thr Ser Ala Glu Glu Asp Phe Asp Ser Gln Val Asp Arg Met Thr
  65                  70                  75                  80
 His Ser Val Asp Thr Thr Gln Pro Leu Thr Pro Ala Ala Pro Val Ile
                  85                  90                  95    
 Thr Gln Trp Ala His Glu Gln Ile Gly His Gly Gly Arg Asp Gly Gly
             100                 105                 110        
 Tyr Ala Trp Ser Gln Gln His Gly Leu Thr Phe Ile Lys Ala Asp Leu
         115                 120                 125            
 Ala Thr Ala Ile Ala Glu Cys Pro Ile Tyr Gln Gln His Arg Pro Lys
     130                 135                 140                
 Pro Ser Pro
 145        



      <210> 1313
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1313
 Met Leu Ala Asn Pro Leu Phe Phe Ile Ser Leu Thr Thr Thr Leu Val
   1               5                  10                  15    
 His Pro Trp Ser Asp Lys Pro Cys Val Pro His Leu Leu Gln Arg Asp
              20                  25                  30        
 Ser Tyr Tyr Val Tyr Thr Gln Gln Glu Leu Lys Glu Lys Leu Tyr Gln
          35                  40                  45            
 Glu Ile Ile Ser Tyr Phe Asp Lys Gly Lys Val Ser Ile Gly Leu Phe
      50                  55                  60                
 Leu Tyr
  65    



      <210> 1314
      <211> 112
      <212> PRT
      <213> Homo sapiens


      <400> 1314
 Met Arg Glu Leu Ala Leu Gly Ile Leu Ile Leu Ser Ser Ser Gly Ser
   1               5                  10                  15    
 Ser Ala Leu Ala Gly Ala Val Phe Gly Gly Ser Asp Pro Val Gly Ser
              20                  25                  30        
 Trp Thr Gln Gly Ser Lys Val Ser Lys Ala Ser Ala Leu Thr Ser Leu
          35                  40                  45            
 Cys Thr Thr Asp Thr Gly Pro Met Pro Leu Thr His Pro Asn His Gly
      50                  55                  60                
 Pro Asp Thr Leu Gln Arg Trp Thr Ser Ser Gln Thr Pro Thr Ser Leu
  65                  70                  75                  80
 Ser Ser Lys Leu Asn Pro Glu Pro Glu Ala Asp Ala Ala Ser Ile Leu
                  85                  90                  95    
 Ile Ala Thr Ser Ile Leu Tyr Lys Gln Ser Asp Pro Tyr Leu Asp Ser
             100                 105                 110        





      <210> 1315
      <211> 359
      <212> PRT
      <213> Homo sapiens


      <400> 1315
 Met Leu Leu Lys Trp Pro Trp Ala Val Val Leu Ala Arg Gln Gly Leu
   1               5                  10                  15    
 Cys Ala Leu Arg Ala Met Gln Gly Ala Val Glu Ala Pro Arg Ser Ser
              20                  25                  30        
 Pro Arg Ala Tyr Glu Gly Arg Leu Lys Asp Gln Arg Glu Gly Pro Arg
          35                  40                  45            
 Ala Leu Phe Trp Glu Pro Gln Asp Phe Thr Ser Ser Gly Ile His Lys
      50                  55                  60                
 Ala Gly Leu Gly Ser Pro Arg Met Gly Pro Tyr Leu Gly Leu Pro Asp
  65                  70                  75                  80
 Ser Gln Glu Val Gln Ala Pro Leu Ala Leu Trp Lys Pro Leu Gly Trp
                  85                  90                  95    
 Lys Gln Gln Gln His Glu Lys Pro Ala Leu Ala Pro Gly Gly Gln Arg
             100                 105                 110        
 Leu Gly Pro Arg Asp Pro Ala Leu Ala Leu Leu Arg Gly Leu Pro Arg
         115                 120                 125            
 Ala Gly Arg Tyr Thr Thr Leu Pro Pro Gly Gly Ala Trp Ser Ser Ala
     130                 135                 140                
 Thr Val Arg Leu Val Val Trp Arg Arg Ala Pro Gly Pro Val Asn Trp
 145                 150                 155                 160
 Asn Glu Ser Ala His Pro Phe Ser Ser Tyr Pro Ala Ala Gln Arg Met
                 165                 170                 175    
 Trp Lys Asn Gly Asp Ala Gly Asn Cys Asn Ala Gly Tyr Leu Asp Asp
             180                 185                 190        
 Thr Gly Ser Phe Leu Asp Asp Leu Leu Leu Ser Pro Cys Gly Val Phe
         195                 200                 205            
 Ser Lys Ser Pro Thr Thr Pro Ser Phe Arg Phe Pro Ile Cys Ser Arg
     210                 215                 220                
 Ser Glu Glu Leu Thr Val Gly Pro Val Leu Cys Pro Arg Pro Gln Ala
 225                 230                 235                 240
 Leu Ala Pro Asp Ala Ala Ala Glu Pro Gly Ala Arg Ser Ser Pro Ala
                 245                 250                 255    
 His Leu Gln Val Trp Val Phe Cys Gly Pro Arg Ser Asn Pro Gln His
             260                 265                 270        
 Tyr Glu Ala Trp Ser Gln Gly Glu Arg Pro Gly Ile Gly Phe Arg Arg
         275                 280                 285            
 Pro Gly Pro Ser Leu Leu Cys Arg Ser Leu Gly Ala Gly Thr Asp Ser
     290                 295                 300                
 Ala Lys Arg Lys Gly Asn Tyr Pro Ile Glu Met Glu Arg Ser Ala Asp
 305                 310                 315                 320
 Thr Pro Ala Ala Gln Ser Trp Asn Thr Arg His Pro Ser Leu Glu Lys
                 325                 330                 335    
 Val Val Leu Ser Ser His Gly Pro Ser Val Thr Leu Ser Thr Tyr Gly
             340                 345                 350        
 Gln Cys Leu Trp Ser Lys Gly
         355                



      <210> 1316
      <211> 158
      <212> PRT
      <213> Homo sapiens


      <400> 1316
 Met Thr Glu Thr Leu Phe Leu Leu Arg Leu Cys Pro Leu Leu Leu Asp
   1               5                  10                  15    
 Pro Asn Gly Ile Ser Tyr Pro Ile Pro Val Trp Leu Asn Leu Gly Lys
              20                  25                  30        
 Leu Phe Pro Arg Gly Val Arg Asn Thr Gly Ala Gln Lys His Trp Leu
          35                  40                  45            
 Thr Glu Gly Ala Ala Lys Glu His Cys Val Ser Asp Asp Ser Glu His
      50                  55                  60                
 Phe Glu Ser Trp Arg Ala Ala Gln Val Ile Tyr Phe Pro Trp Val Ala
  65                  70                  75                  80
 Tyr Thr Arg Phe Phe Pro Leu Pro Tyr Glu Gly Gln Tyr Lys Pro Leu
                  85                  90                  95    
 Asp Leu Thr Arg Ser Gly His Val Pro Ala Cys Thr Ile His Asp Thr
             100                 105                 110        
 Phe Leu Phe Tyr Ser Leu Ala Met Arg Glu Cys His Pro Tyr Pro Asp
         115                 120                 125            
 Ala Ser His Leu Ser His Ile Gln Asp Ser Glu Ser Pro Ser Pro Leu
     130                 135                 140                
 Gln Gln Ile Pro Ile Ala Gln Arg His Thr Pro Pro Tyr Glu
 145                 150                 155            



      <210> 1317
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 1317
 Met Thr Phe Pro Val Ala Val Ala Gln Met Leu Cys Pro His Thr Lys
   1               5                  10                  15    
 Ala Leu Ile Leu Tyr Tyr Ser Leu Ser Phe Ala Cys Leu Val Thr Phe
              20                  25                  30        
 Val Arg Ser Ser Gln Lys Gly Ser Leu Ala Met Val Thr Lys Asn Val
          35                  40                  45            
 Lys Gly Lys Ser Met Leu Gln Arg Lys Leu Leu Ser Leu His Ser Thr
      50                  55                  60                
 Pro Leu Ser Ala Phe Ile Ile Ala Ser His Thr Lys His Val Val Tyr
  65                  70                  75                  80
 Lys Ile Lys Ala Leu Leu Phe Leu Arg Asn Ser Lys Met Phe Trp Tyr
                  85                  90                  95    
 Ala Asn Ile Ser Asn Ser Leu Ser Thr Ser Met Gln Asn Thr Asp Ser
             100                 105                 110        
 Asp Glu Pro Lys Arg Ser Tyr Glu Val Gly Ile Leu Arg Pro Thr Val
         115                 120                 125            
 Gln Thr Arg Lys Leu Ser His Ala Asp Val Asp Lys Val Glu Leu Gly
     130                 135                 140                
 Ile Pro Pro Thr Val Gly Gly Ser Phe Cys Lys Val Asn Ile Asn Thr
 145                 150                 155                 160
 Cys Ser Arg Asn Lys His Glu Asp Arg Ile Ser Val
                 165                 170        



      <210> 1318
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 1318
 Met Met Asp Cys Gly Leu Arg Phe Met Gly Cys Thr Ile Leu Ala Leu
   1               5                  10                  15    
 Thr Cys Val His Val Ala Pro Leu Met Ser Ala Thr Glu Gln Glu Thr
              20                  25                  30        
 Gly Lys Thr Thr His Met Ile Phe Arg Gln Leu Glu Glu Glu Glu Glu
          35                  40                  45            
 Asn Ala Phe Pro Ala Val Pro Glu Lys Pro Val Leu Gln Thr Ala Asn
      50                  55                  60                
 Met Val Trp Asn Lys Val Leu Thr Leu Thr Trp Tyr Leu Val Leu Ile
  65                  70                  75                  80
 Leu Arg Leu Tyr Glu Tyr Ser Thr Asp Phe Ser Thr Pro Lys Lys Ser
                  85                  90                  95    
 Phe Arg Ser Lys Ala Thr Phe Asn Ile Gln Thr Ile Ser Thr Ser Val
             100                 105                 110        
 Ala Pro Thr Pro Thr Ala Ile Phe Glu Thr Asp Met Ala Leu Lys Glu
         115                 120                 125            
 Ala Arg Ile Thr Leu
     130            



      <210> 1319
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1319
 Met Pro Tyr Trp Phe Ser Val Thr Leu Leu Leu Leu Gln Ile Phe Pro
   1               5                  10                  15    
 Leu Leu Asn Phe Pro Tyr Ile Thr Leu Arg Asp Cys Ala Ile Gly His
              20                  25                  30        
 Cys Trp Asp Val Thr Glu Arg Pro Phe Glu Asp Lys Gly Pro Lys Asn
          35                  40                  45            
 Ser Ser Gly Asp Ser Ala Trp Pro Val Leu Val Met Gly Lys Pro Gly
      50                  55                  60                
 Ala Ser Pro Ser His Gly Leu Gly Glu Ala Ser Ser Ala Glu Gly Gln
  65                  70                  75                  80
 Ser Ser His Asn Ser Pro Leu Leu Ala Val Ser Thr Ser Gln Thr Gly
                  85                  90                  95    
 Ala Arg Thr Arg Asn Asn Ser Gln His Leu Arg Ile Lys Ser Pro Leu
             100                 105                 110        
 Leu Asp Ala Leu Val Phe Pro Asp Tyr Arg Pro Thr Trp Ser Leu Phe
         115                 120                 125            
 Glu Gly Val Ala Ala Met Gly
     130                 135



      <210> 1320
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1320
 Met Val Thr Val Leu Val Cys Trp Ala Leu Gln Val Leu Gln Leu Tyr
   1               5                  10                  15    
 Gln Ile Thr Gln Ile Asn His Gly Leu Met Met Val Gly Pro Ser Gly
              20                  25                  30        
 Ser Gly Lys Ser Met Ala Trp Arg Val Leu Leu Lys Ala Leu Glu Arg
          35                  40                  45            
 Leu Glu Gly Val Glu Gly Val Ala His Ile Ile Asp Pro Lys Ala Ile
      50                  55                  60                
 Ser Lys Asp His Leu Tyr Gly Thr Leu Asp Pro Asn Thr Arg Glu Trp
  65                  70                  75                  80
 Thr Asp Gly Leu Phe Thr His Val Leu Arg Lys Tyr Val Phe Phe Asp
                  85                  90                  95    
 Leu Cys Leu Cys Ser Pro Gly Tyr Gly Arg
             100                 105    



      <210> 1321
      <211> 51
      <212> PRT
      <213> Homo sapiens


      <400> 1321
 Met Leu Leu Leu Ser Trp Thr Val Leu Glu Ala Arg Gln Trp Leu Leu
   1               5                  10                  15    
 Ser Thr Met Asp Glu Val Ala Phe Lys Asp Lys Glu Gln Val Gln Ser
              20                  25                  30        
 Thr His Ser Pro Ala Pro Glu Lys Arg Lys Val Asn Gly Ser Ala Phe
          35                  40                  45            
 Arg Gln Pro
      50    



      <210> 1322
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1322
 Met Asp Trp Ile Gln Leu Arg Lys Phe Trp Ile Phe Phe Ser Trp Cys
   1               5                  10                  15    
 Thr Glu Glu Lys Arg Arg Asp Val Glu Phe Ser Asp Leu Leu Glu Arg
              20                  25                  30        
 Glu Glu Leu Ser Thr Glu Gly Ser Val Leu Ser Leu Leu Pro Tyr Gly
          35                  40                  45            
 Lys Ser Thr Val Val Leu Leu Gly Tyr His Pro Leu Gln Asn Leu Lys
      50                  55                  60                
 Thr Arg Glu Ala Ser Cys Val Asn Glu Leu Ile Lys Pro Leu
  65                  70                  75            



      <210> 1323
      <211> 165
      <212> PRT
      <213> Homo sapiens


      <400> 1323
 Met Lys Ile Ala Ala Leu Leu Gly Cys Met Met Met Ala Ala Arg Cys
   1               5                  10                  15    
 Gly Thr Leu Ser Ala Met Arg Asp Leu Ser Phe Ser Asp Glu Asn Arg
              20                  25                  30        
 Arg Leu Ala Val Gly Thr Ala Ala Ala Ala Val Ser Thr His Lys Gly
          35                  40                  45            
 Val Trp Leu Trp Ser Leu Phe Val Cys Pro Ser Arg Leu Pro Pro Phe
      50                  55                  60                
 Ser Lys Asp Gln His His Pro Ser Ser Phe Gln Ala Lys Asn Pro Gly
  65                  70                  75                  80
 Val Ile Leu Asp Phe Ser Phe Phe Pro Ile Pro His Trp Ala Tyr Glu
                  85                  90                  95    
 Gln Ile Leu Ser Ala Leu Leu Gln Ala Lys Cys Gly Ile Gly Lys Lys
             100                 105                 110        
 Glu Lys Leu Gln Asn Ile Pro Gln Ile Gln Leu Leu Leu Thr Asn Thr
         115                 120                 125            
 Ile Leu Val Thr Leu Val Gln Thr Pro Ser Ile Ala Pro Leu Asp Leu
     130                 135                 140                
 Arg Val Cys Cys Leu Thr Cys Phe Tyr Ala Ser Leu Leu Val Asp Asn
 145                 150                 155                 160
 Ile Gln Gln Ile Ile
                 165



      <210> 1324
      <211> 298
      <212> PRT
      <213> Homo sapiens


      <400> 1324
 Met Pro Gly Pro Met Ser Leu Trp Leu Leu Leu Leu Val Leu Pro Leu
   1               5                  10                  15    
 Ser Leu Glu His Ser Asp Leu Arg Ile Cys Phe Pro Gly Gln Val Val
              20                  25                  30        
 Ser Met Glu Ser Ser Ser Thr Gly Phe Ile Trp Thr Asp Val Arg Ala
          35                  40                  45            
 Trp Gln Thr Ser Asn Arg His Val Ser Ser Trp Arg Glu Pro Arg His
      50                  55                  60                
 Ser Arg Met Pro Pro Gly Ala Gly Leu Met Glu Arg Ile Gln Ala Ile
  65                  70                  75                  80
 Ala Gln Asn Val Ser Asp Ile Ala Val Lys Val Asp Gln Ile Leu Arg
                  85                  90                  95    
 His Ser Leu Leu Leu His Ser Lys Val Ser Glu Gly Arg Arg Asp Gln
             100                 105                 110        
 Cys Glu Ala Pro Ser Asp Pro Lys Phe Pro Asp Cys Ser Gly Lys Val
         115                 120                 125            
 Glu Trp Met Arg Ala Arg Trp Thr Ser Asp Pro Cys Tyr Ala Phe Phe
     130                 135                 140                
 Gly Val Asp Gly Thr Glu Cys Ser Phe Leu Ile Tyr Leu Ser Glu Val
 145                 150                 155                 160
 Glu Trp Phe Cys Pro Pro Leu Pro Trp Arg Asn Gln Thr Ala Ala Gln
                 165                 170                 175    
 Arg Ala Pro Lys Pro Leu Pro Lys Val Gln Ala Val Phe Arg Ser Asn
             180                 185                 190        
 Leu Ser His Leu Leu Asp Leu Met Gly Ser Gly Lys Glu Ser Leu Ile
         195                 200                 205            
 Phe Met Lys Lys Arg Thr Lys Arg Leu Thr Ala Gln Trp Ala Leu Ala
     210                 215                 220                
 Ala Gln Arg Leu Ala Gln Lys Leu Gly Ala Thr Gln Arg Asp Gln Lys
 225                 230                 235                 240
 Gln Ile Leu Val His Ile Gly Phe Leu Thr Glu Glu Ser Gly Asp Val
                 245                 250                 255    
 Phe Ser Pro Arg Val Leu Lys Gly Gly Pro Leu Gly Glu Met Val Gln
             260                 265                 270        
 Trp Ala Asp Ile Leu Thr Ala Leu Tyr Val Leu Gly His Gly Leu Arg
         275                 280                 285            
 Val Thr Val Ser Leu Lys Glu Leu Gln Arg
     290                 295            



      <210> 1325
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 1325
 Met Thr Cys Ser Gly Val Leu Ala Gln Leu Pro Ile Trp Ser Gly Ile
   1               5                  10                  15    
 Ser Leu Ala Leu Leu Arg Leu Arg Leu Ser Gln Glu Leu Glu Glu Glu
              20                  25                  30        
 Val Glu Asp Glu Asp Glu Lys Glu Glu Glu Lys Glu Arg Ser Ser Ser
          35                  40                  45            
 Gln Arg Thr Pro Ser Gly Cys Arg Gly Lys Gln Arg Arg Arg Arg Leu
      50                  55                  60                
 Gly His Arg Arg Arg Leu Gly Ser His Gly Arg Arg Gly Arg Arg Arg
  65                  70                  75                  80
 Arg Gly Arg Asp Pro Val Ser Glu Asp Cys Glu Ser Pro Arg Arg Gly
                  85                  90                  95    
 Arg Gly Arg Gly Gln Gly Ala Pro Thr His Arg Gly Thr Ser Gly Lys
             100                 105                 110        
 Glu Pro Ala Gly Gln Gly Gly Val Trp Gly Ala Gly Ser Glu Lys Arg
         115                 120                 125            
 Ala Gln Ala Leu Gly Pro Ser Pro Gly Ile Ala Arg Arg Gly Ile His
     130                 135                 140                
 Pro Ala Leu Pro Leu Ser Cys
 145                 150    



      <210> 1326
      <211> 123
      <212> PRT
      <213> Homo sapiens


      <400> 1326
 Met Val His Pro Met Leu Val Asp Gly Leu Gly Arg Leu Tyr Glu Gln
   1               5                  10                  15    
 Ile Leu Leu Trp Ile Leu Phe Pro Ala Trp Lys Ala Ala Ser Val Leu
              20                  25                  30        
 Lys Val Gln Ser Glu Cys Ala Leu Thr Leu Ala Leu Ala Gln Val Cys
          35                  40                  45            
 Ala Val Glu Ala Val Ala Val Gly Gly Val Val Thr Ala Gly Arg Lys
      50                  55                  60                
 Met Leu Asn Ser Ser Glu Gln Arg Arg Pro His Gly Val Leu Asp Ser
  65                  70                  75                  80
 Val Trp Pro Gly Ile His Gly Ala Leu Cys Ala Gly Arg Trp Leu Arg
                  85                  90                  95    
 Thr Val Ser Ile Ser Leu Pro Ser Met Leu Asn Glu Gly Val Phe Arg
             100                 105                 110        
 Ile Ser Lys Thr Arg Lys Glu Gln Phe Leu Ser
         115                 120            



      <210> 1327
      <211> 141
      <212> PRT
      <213> Homo sapiens


      <400> 1327
 Met Leu Leu Leu Trp Val Ser Val Val Ala Ala Leu Ala Leu Ala Val
   1               5                  10                  15    
 Leu Ala Pro Gly Ala Gly Glu Gln Arg Arg Arg Ala Ala Lys Ala Pro
              20                  25                  30        
 Asn Val Val Leu Val Val Ser Asp Ser Phe Phe Ser Cys Ser Ser Leu
          35                  40                  45            
 Pro Arg Ile Glu Ser Ala Leu Val Arg Val Thr Ser Cys Leu His Thr
      50                  55                  60                
 Ala Asn Ser Asn Val His Phe Leu Ala Ser Phe Gln Val Ser Tyr Ile
  65                  70                  75                  80
 Pro Glu Lys Ala Ser Leu Ser Thr Leu Ser Asn Asp Gly Arg Leu Thr
                  85                  90                  95    
 Phe His Pro Gly Ser Gln Val Val Lys Leu Pro Phe Ile Asn Phe Met
             100                 105                 110        
 Lys Thr Arg Gly Thr Ser Phe Leu Asn Ala Tyr Thr Asn Ser Pro Ile
         115                 120                 125            
 Cys Cys Pro Ser Arg Ala Glu Cys Lys Leu Asn Leu Lys
     130                 135                 140    



      <210> 1328
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1328
 Met Pro Val Trp Trp Arg Arg Arg Arg Leu Arg Ala Arg Ser Trp Ala
   1               5                  10                  15    
 Leu Arg Gly Gln Lys Ala Thr Leu Pro Val Pro Pro Arg Pro Thr Ser
              20                  25                  30        
 Phe Pro His Lys Pro Phe Ala Gln Ser Arg Phe Val Ser Asn His Leu
          35                  40                  45            
 Glu Gly Leu Ala Asp Leu Ser Pro Ser Thr Pro Val Arg Cys Pro Leu
      50                  55                  60                
 Leu Arg Asn Trp Ala Arg Ala Phe
  65                  70        



      <210> 1329
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1329
 Met Ala Ala Gly Cys Leu Leu Ala Leu Thr Leu Thr Leu Phe Gln Ser
   1               5                  10                  15    
 Leu Leu Ile Gly Pro Ser Ser Glu Glu Pro Phe Pro Ser Ala Val Thr
              20                  25                  30        
 Ala Gln Thr Arg Phe Ile Pro Arg Tyr Trp Met His Leu Thr Ala Phe
          35                  40                  45            
 Arg Leu Asp Ala Cys Trp Leu Pro Ala Ala Glu Arg Ala Val His Ala
      50                  55                  60                
 Gly Gly Ser Gln Val Ser Val Gln Glu Ser Gly Gly Cys Thr Phe Tyr
  65                  70                  75                  80
 Pro Gly Glu Gly Glu Cys Leu Ile Phe Val Val Ile Glu Leu Gln
                  85                  90                  95



      <210> 1330
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1330
 Met Leu Pro Leu Gln Val Arg Arg Pro Gly Ala Ala Ala Gly Leu Leu
   1               5                  10                  15    
 Trp Arg Leu Ala Ser Arg Arg Cys Arg Cys Thr Gly His Cys Tyr Phe
              20                  25                  30        
 Pro Val Phe Ala Ser Val Leu Leu Val Cys Gly Glu Met Pro Ser Arg
          35                  40                  45            
 Arg Pro Leu Ser Pro Thr Pro Ser Pro Arg Gly Gly Pro Glu Phe Gln
      50                  55                  60                
 Pro Leu Leu Pro Gln Gly Asn Ile Leu Gly Asn Gln Val Phe Pro Gly
  65                  70                  75                  80
 Arg Ile
        



      <210> 1331
      <211> 192
      <212> PRT
      <213> Homo sapiens


      <400> 1331
 Met Gly Pro Val Ser Leu Leu Met Gln Asn Pro Val Thr Lys Leu Gln
   1               5                  10                  15    
 Leu Cys Gly His Ala Trp Leu Phe Trp Gly Leu Trp Gly Ala Leu Ala
              20                  25                  30        
 Ile Gly Gly Gln Arg Leu Gly Gly Gly His Leu Leu Asp Asp Arg Ala
          35                  40                  45            
 Ser Pro Val His Leu Leu Ala Gly Val Glu Gly Gly Val Gly Gly Gly
      50                  55                  60                
 Thr Gln Val Asn Ile His Gly Val Ser Ser Gln Ser His Asp Gly Gly
  65                  70                  75                  80
 Gly Val Ala Pro Pro Leu Gly Val Asp Ala Leu Leu Glu His Leu Cys
                  85                  90                  95    
 Arg Gly Arg Arg Glu Leu Gly Val Glu Gly His Ala Gly Gly Gly Gly
             100                 105                 110        
 Ala His Asp Pro Phe Arg Thr Arg Leu Ser Ser Gly Phe Arg Leu Gly
         115                 120                 125            
 Ser Leu Val Asp Glu Arg Met Pro Val Pro Gln Leu Leu Ala Ser Val
     130                 135                 140                
 Phe Leu Val Glu Gly Pro Glu Arg Gln Ala Gly Thr Pro Ala Pro Thr
 145                 150                 155                 160
 Tyr Leu Ser Lys Lys Val Ala Arg Ser Leu Arg Ser Lys Thr Leu Cys
                 165                 170                 175    
 Phe Thr Pro Ala His Arg Trp Gln Phe Ile Ser Trp Pro Arg Val Met
             180                 185                 190        





      <210> 1332
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 1332
 Met Val Ile Leu Asn Ala Leu Gln Arg Arg Ala Phe Leu Cys Ala Ala
   1               5                  10                  15    
 Asn Val Lys Ile Pro Arg Leu Arg Ile Lys Val Lys Thr Lys Glu Ala
              20                  25                  30        
 Ser Ala Gln Val Val Lys Glu Glu Cys Asn Lys Tyr Leu Leu Phe Leu
          35                  40                  45            
 Leu Pro Val Pro Ser Ala Gly Leu Leu Pro Ser Ile Met Glu Ile Ala
      50                  55                  60                
 Asp Pro Phe Ser Ser Phe Gly Ser Glu Asp Lys Cys Tyr Thr Leu Thr
  65                  70                  75                  80
 Pro Pro Leu Pro Arg His Thr Glu Lys Ser Ser Asp Ser Gln Glu Lys
                  85                  90                  95    
 Gly His Phe Glu Ala Gly Val Glu Pro Lys Ser Arg Gly Ser Thr Pro
             100                 105                 110        
 Gly Gln Tyr Pro Gly Ile Gly Cys Phe Ala Arg Phe Arg Glu Tyr Gln
         115                 120                 125            
 Ile Gly Met Arg His Leu Thr Thr Arg Pro Ala Met His Arg Ala Gln
     130                 135                 140                
 Val Leu Phe Pro Leu Ser Phe
 145                 150    



      <210> 1333
      <211> 183
      <212> PRT
      <213> Homo sapiens


      <400> 1333
 Met Gly Thr Val Gly Ser Gly Ala Phe Arg Ser Thr Leu Ser Phe Ile
   1               5                  10                  15    
 Trp Thr Trp Gln Phe Phe Pro Asp Asp Pro Pro Gly Leu Pro Glu Gln
              20                  25                  30        
 Ser Gly Lys Tyr Ser Trp Leu Trp Ala Gln Ser Arg Ala Leu Pro Arg
          35                  40                  45            
 Asp Ser Thr Gly Trp Ala Arg Pro Asp Val Gly Val Leu Asp Ala Gly
      50                  55                  60                
 Pro Ala Ala Ile Leu Gln Pro Gln Gly Thr Glu Gly Gln Ala Ala Gly
  65                  70                  75                  80
 Asp Ser Glu Leu Thr Val Gly Ala Gly Pro Ala Gly Phe Thr Ala Cys
                  85                  90                  95    
 Ser Pro Leu Ser Gly Cys Arg Thr Pro Tyr Thr His His Phe Pro Ala
             100                 105                 110        
 Ser Arg Met Ser Cys His Leu Asn Cys Ala Ser Pro Arg Thr Tyr Arg
         115                 120                 125            
 Ser Gln Gly Asn Arg Gly Cys Glu Arg Val Ala Arg Gly Ser Gln Ser
     130                 135                 140                
 Gly Gly Gly Glu Arg Gly Asp Gly Ser Gln Val Pro Val Pro Ala Pro
 145                 150                 155                 160
 Ala Arg Asp Lys Asp Pro Pro Asn Ala Arg Ser His Ala Leu Leu Ser
                 165                 170                 175    
 Cys Pro Leu Gln Leu Arg Ala
             180            



      <210> 1334
      <211> 149
      <212> PRT
      <213> Homo sapiens


      <400> 1334
 Met Arg Glu Lys Gln His Leu Lys Glu Ala Ala Thr Ser His Ala Phe
   1               5                  10                  15    
 His Val Leu Val Thr Val Ile Val Val Leu Ser Lys Leu Gly Leu Ser
              20                  25                  30        
 Cys Phe Arg Asp Glu Asn Asn Lys Glu Asn Tyr Pro Asp Ala Gly Ala
          35                  40                  45            
 Leu Val Glu Glu His Ala Pro Pro Ser Trp Glu Pro Gln Gln Gln Asn
      50                  55                  60                
 Val Glu Ala Thr Val Leu Val Asp Ser Val Leu Arg Pro Ser Met Gly
  65                  70                  75                  80
 Asn Phe Lys Ser Arg Lys Pro Lys Ser Ile Phe Lys Ala Glu Ser Gly
                  85                  90                  95    
 Arg Ser His Gly Glu Ser Gln Val Ala Ala Leu Ser Ser Gln Ala Phe
             100                 105                 110        
 Ala Lys Thr Val Glu Gly Ser Lys Asp Met Ser Asp Ser Gly Ile Gln
         115                 120                 125            
 Glu Leu Pro Pro Asn Leu Ser Ser Met Tyr Cys Trp Met Trp Lys Gly
     130                 135                 140                
 Trp Glu Asn Gly Ser
 145                



      <210> 1335
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1335
 Met Ile Leu Thr Met Leu Leu Met Leu Lys Leu Cys Thr Glu Val Arg
   1               5                  10                  15    
 Val Ala Asn Glu Leu Asn Ala Arg Arg Arg Ser Phe Thr Glu Gln Glu
              20                  25                  30        
 Val Leu Ile Cys Ala Trp Pro Ile Arg Ser Asp Gly Thr Arg Ser Gly
          35                  40                  45            
 Val Ser Ser Val Cys Val Ala Cys Thr Gln Asn Thr Pro Phe Gln Phe
      50                  55                  60                
 Cys Cys Asp Ser Gly Thr Glu Val Thr Val Cys Cys Phe Gln Pro Leu
  65                  70                  75                  80





      <210> 1336
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1336
 Met Thr Ile Cys Val Ser Leu Gly Phe Met Arg Ser Leu Cys Asn Ser
   1               5                  10                  15    
 Ala Ser Cys Leu Tyr Asn Val Glu Ile Thr Ala Ser Leu Met Glu Trp
              20                  25                  30        
 Pro Gly Val Leu Lys Lys Val Ala Gln Glu Pro Ile Trp Ile Trp Arg
          35                  40                  45            
 Ile Val Val Ser Tyr Tyr Asp Arg Arg Ser Asp Gly Leu Thr Gln Thr
      50                  55                  60                
 Arg Asp Ala Leu Leu Arg Pro Trp Ser Ser Ser Glu Arg Glu His Leu
  65                  70                  75                  80
 Met Asp Leu Leu Asn Val Lys Ser Met Pro Lys Glu Pro Arg Gln Glu
                  85                  90                  95    
 Glu Leu Cys His Gln Thr Phe
             100            



      <210> 1337
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1337
 Met Tyr Lys Ala Gln Phe Leu Ala Ala Ser Pro Gly Arg Cys Leu Gly
   1               5                  10                  15    
 Leu Leu Ala Ala Ser Asn His His Ala Lys Ser Ile His Gly Phe Arg
              20                  25                  30        
 Arg Leu Val Lys Thr Met Arg Asn Arg Pro Glu Glu Gln Asn Lys Gly
          35                  40                  45            
 Ile Ser Ser Tyr Thr Lys Arg Val Asn Ala Val Thr Lys Gly Phe Trp
      50                  55                  60                
 Ala Asp Pro Gln Leu Pro Arg Leu Glu Asn Ser Gly Cys Pro Gln Gly
  65                  70                  75                  80
 Pro Leu Lys Val Pro Trp Arg Val Ala Val Asn Ala Phe Trp Lys Arg
                  85                  90                  95    
 Ala Val Gln Glu Lys Lys Glu Leu Tyr Val His Lys Val Gln Ala
             100                 105                 110    



      <210> 1338
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1338
 Met Gly Leu Ile Ala Val Thr Val Thr Ala Ala Thr Ala Gly Val Ala
   1               5                  10                  15    
 Leu His Lys Ser Ile Gln Thr Val His Phe Val Asp Lys Trp Gln Lys
              20                  25                  30        
 Phe Tyr Ser Asp Val Glu Phe Ser Val Lys Glu Gly Glu Lys Lys Gln
          35                  40                  45            
 Ala Thr Trp Lys Ala Tyr Leu Arg Thr Ser Ser Met Lys Ile Ser Pro
      50                  55                  60                
 Asn Ser Arg Glu Asp Asn Ile Arg Ile Gln Glu Thr Gln Arg Thr Pro
  65                  70                  75                  80
 Val Arg Tyr Tyr Thr Arg Gln Leu Cys Ala Arg His Thr Val Ile Arg
                  85                  90                  95    
 Leu Ser Thr Ile Lys Val Lys Gly Arg Ile Ile His Asp Glu His Ala
             100                 105                 110        
 Tyr Lys Asn Pro Gln Glu Arg Arg Gly Ser His Pro Gln Ser Lys Leu
         115                 120                 125            
 Ile Arg Leu Thr Val Asp Leu Ser Ala Glu Thr Leu
     130                 135                 140



      <210> 1339
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1339
 Met Ser Leu Ala Asn Val Tyr Leu Leu Ser Phe Ile Val Leu Phe Arg
   1               5                  10                  15    
 Gly Phe Leu Pro Leu Ser Ser Tyr Glu Thr Asn Val Phe Leu Thr Val
              20                  25                  30        
 Asn Trp Val Arg Phe Pro Asp Leu Ser Phe Pro Asn Glu Ser Phe Pro
          35                  40                  45            
 Gln Thr Gln Ile Phe Ser His Leu Cys Ile Ile Asp Asn
      50                  55                  60    



      <210> 1340
      <211> 205
      <212> PRT
      <213> Homo sapiens


      <400> 1340
 Met Pro Ile His Leu Ser Ile Ile Met Tyr Ser Leu Cys Phe Val Val
   1               5                  10                  15    
 Tyr Ile Cys Ile Asp Phe Thr Asn Gly Cys Asp Leu Val Gly Ser Ser
              20                  25                  30        
 Ser Leu His Asn Met Leu Val Cys Lys Thr Phe Val Gln Gln Asn Cys
          35                  40                  45            
 Arg Cys Ser Val Glu Ser Thr Gly Asp Cys Ser Asp Thr Lys Asp Lys
      50                  55                  60                
 Tyr Ala His Met Thr Leu Thr Asp Lys Thr Leu Phe Arg Lys Thr Gly
  65                  70                  75                  80
 Lys Glu Glu Pro Arg Asn His Ala Thr Thr Pro Tyr Tyr Lys Lys Pro
                  85                  90                  95    
 Leu Tyr Gly Ile Ser His Lys Val Met Glu Lys Lys Asn Pro Pro Ser
             100                 105                 110        
 Gly Asp Leu Leu Asn Thr Thr Gly Ala Ala Thr Asn Ser Asp Pro Asn
         115                 120                 125            
 Ile Tyr Phe Leu Ile Gln Glu Met Phe Tyr Met Leu Asn Thr Leu Thr
     130                 135                 140                
 Ser Asn Arg Ser Gln Leu His Ser Lys Val Asp Leu Leu Ser Leu Lys
 145                 150                 155                 160
 Val Glu Ala Val Tyr Pro Val Glu Lys Val Glu Glu Val Trp His Cys
                 165                 170                 175    
 Glu Cys Ile Pro Ser Asn Asp Glu Gln Cys His Cys Pro Asn Arg Lys
             180                 185                 190        
 Lys Cys Asn Ile Leu Lys Lys Ala Lys Lys Val Glu Lys
         195                 200                 205



      <210> 1341
      <211> 354
      <212> PRT
      <213> Homo sapiens


      <400> 1341
 Met Leu Ser Met Leu Ala Ala Gly Leu Leu Cys Val Pro Trp Val Pro
   1               5                  10                  15    
 Gln Ser His Thr Ala Thr Arg Asn Gln Ser Leu Leu Val Met Gly Leu
              20                  25                  30        
 Gln Arg Ser Pro Lys Met Ser Ser Arg Ala Leu Leu Val Gly Ala Ile
          35                  40                  45            
 Gly Asp Glu Glu Glu Trp Val Thr Leu Tyr Glu Glu Glu Asn Glu Pro
      50                  55                  60                
 Asp Ala Gln Met Leu Glu Ile Pro Asn Leu Thr Pro Tyr Thr His Tyr
  65                  70                  75                  80
 Arg Phe Arg Met Lys Gln Val Asn Ile Val Gly Pro Ser Pro Tyr Ser
                  85                  90                  95    
 Pro Ser Ser Arg Val Ile Gln Thr Leu Gln Ala Pro Pro Asp Val Ala
             100                 105                 110        
 Pro Thr Ser Val Thr Val Arg Thr Ala Ser Glu Thr Ser Leu Arg Leu
         115                 120                 125            
 Arg Trp Val Pro Leu Pro Asp Ser Gln Tyr Asn Gly Asn Pro Glu Ser
     130                 135                 140                
 Val Gly Tyr Arg Ile Lys Tyr Trp Arg Ser Asp Leu Gln Ser Ser Ala
 145                 150                 155                 160
 Val Ala Gln Val Val Ser Asp Arg Leu Glu Arg Glu Phe Thr Ile Glu
                 165                 170                 175    
 Glu Leu Glu Glu Trp Met Glu Tyr Glu Leu Gln Met Gln Ala Phe Asn
             180                 185                 190        
 Ala Val Gly Ala Gly Pro Trp Ser Glu Val Val Arg Gly Arg Thr Arg
         195                 200                 205            
 Glu Ser Val Pro Ser Ala Ala Pro Glu Asn Val Ser Ala Glu Ala Val
     210                 215                 220                
 Ser Ser Thr Gln Ile Leu Leu Thr Trp Thr Ser Val Pro Glu Gln Asp
 225                 230                 235                 240
 Gln Asn Gly Leu Ile Leu Gly Tyr Lys Ile Leu Phe Arg Ala Lys Asp
                 245                 250                 255    
 Leu Asp Pro Glu Pro Arg Ser His Ile Val Arg Gly Asn His Thr Gln
             260                 265                 270        
 Ser Ala Leu Leu Ala Gly Leu Arg Lys Phe Val Leu Tyr Glu Leu Gln
         275                 280                 285            
 Val Leu Ala Phe Thr Arg Ile Gly Asn Gly Val Pro Ser Thr Pro Leu
     290                 295                 300                
 Ile Leu Glu Arg Thr Lys Asp Asp Ala Pro Gly Pro Pro Val Arg Leu
 305                 310                 315                 320
 Val Phe Pro Glu Val Arg Leu Thr Ser Val Arg Ile Val Trp Gln Pro
                 325                 330                 335    
 Pro Glu Glu Pro Asn Gly Ile Ile Leu Glu Lys Ile Gln Thr Ile Ser
             340                 345                 350        
 Arg Ala
        



      <210> 1342
      <211> 274
      <212> PRT
      <213> Homo sapiens


      <400> 1342
 Met Arg Ala Leu Lys Leu Gln Arg Arg Lys Ser Phe Trp Ile Val Val
   1               5                  10                  15    
 Ala Trp Glu Ala Phe Val Gln Leu Val Asn Tyr Glu Cys Lys Val Gly
              20                  25                  30        
 Glu Trp Lys Gly Leu Ala His Cys Val Ser Gln Asn Asn Lys Tyr Arg
          35                  40                  45            
 Thr Thr Tyr Ile Ile Ala Gly Val Pro Asn Pro Gln Glu Pro Gly Tyr
      50                  55                  60                
 Thr Ala Gly Gly Gln Leu Lys Gly Asn Asp Leu Thr Val Leu His Leu
  65                  70                  75                  80
 Leu Val Ile Glu Gly Lys Trp Glu Ala Val Arg Lys Phe Pro Phe Lys
                  85                  90                  95    
 Lys Tyr Ile Val Asn Thr Ala Ile Val Lys Glu Ala Arg Lys Tyr Trp
             100                 105                 110        
 Val Glu Glu Gly Ser Ser Leu Ala Lys Ala Thr Arg Ser Asn Pro Gly
         115                 120                 125            
 Tyr Leu Gln Pro Tyr Met Arg Thr Gly Ile Pro Val Phe Ala Pro Pro
     130                 135                 140                
 Lys Leu Pro Phe Gly Pro Pro Cys Pro Leu Ser Cys Thr His Ile Asn
 145                 150                 155                 160
 Pro Lys Pro Gln Ala Pro Glu Ala Asp Gln Gln Leu Pro Ile His Leu
                 165                 170                 175    
 Ala Glu Ser His Phe His His Ser Ile Lys Pro Arg Ile His Pro Ser
             180                 185                 190        
 Ser Pro Cys Val Thr Arg Phe Phe Leu Asp Ala Glu Arg Glu Leu Gly
         195                 200                 205            
 Ile Gln Lys Ala Val Pro Trp Ser Phe Thr Leu Val Lys Lys Gln Lys
     210                 215                 220                
 Ser Leu Gly Leu Pro Ser Val Gln Asp Phe Gly Ser Val Tyr Lys Met
 225                 230                 235                 240
 Asn Ile Trp Ser Asp Val Ala Cys Cys Asp Pro Gln Leu Gln Gln Pro
                 245                 250                 255    
 Ala Ala Ser Ala Gln Thr Ser Ala Ile Ser Gln Leu Ser Arg Val Thr
             260                 265                 270        
 Glu Ser
        



      <210> 1343
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1343
 Met Ser His Asn Thr Val Leu Cys Val Leu His Leu Gln Cys Tyr Ala
   1               5                  10                  15    
 Ile Pro Phe Ser Cys Val His Ser Glu Thr Glu Ala Ile Cys Asp Pro
              20                  25                  30        
 Ser Ser Ser Cys Leu Ala Leu Gln Ser Thr Gly Ser Thr Asp Leu Thr
          35                  40                  45            
 Ile Asn Tyr Lys Tyr Asn Ile Arg Asn Ser Asp Thr Arg Leu Cys Asn
      50                  55                  60                
 Ile Gly Cys
  65        



      <210> 1344
      <211> 186
      <212> PRT
      <213> Homo sapiens


      <400> 1344
 Met Ala Gly Trp Met Thr Ile Leu Glu Gly Val Pro Gly Leu Ala Gly
   1               5                  10                  15    
 Phe Leu Phe Leu Pro Leu Lys His Pro Ser Pro Asp Pro Gln Ser Lys
              20                  25                  30        
 Gly Thr Gly Glu Thr Ser Arg Gln Ile Ala Ser Arg Gln Lys Leu Arg
          35                  40                  45            
 Ser Trp Leu Gly Asn Ser Val Gln Arg Glu Arg Ala Cys Thr Gly Arg
      50                  55                  60                
 Thr Glu Arg Val His Leu Arg Ile Thr Pro Gly Asp Asp Ser Arg Lys
  65                  70                  75                  80
 Arg Ser Ser Ala Ser His Tyr Arg Val Ala Gly Ile Ser Arg Leu Thr
                  85                  90                  95    
 Leu Ser Leu Asp Arg Glu Gln Leu Tyr Leu Glu Gln Ser Thr Glu Gly
             100                 105                 110        
 Pro Glu Gln Asp Lys Arg Glu Gly Lys Ser Ala Arg Ser Ser Ser Arg
         115                 120                 125            
 Glu Pro Thr Gly Gln Pro Arg Thr Leu Leu Gly Gly Met Arg Ala Arg
     130                 135                 140                
 Lys Arg Lys Thr Leu Val Leu Gly Pro Phe Pro Arg Val Ile Ser Gly
 145                 150                 155                 160
 Ser Asn Ala Lys Met Asp Thr Leu Ser Pro Ala Cys Ala Cys Ala Phe
                 165                 170                 175    
 Ala Leu Tyr Gly Ile Pro Lys Pro Ala Ala
             180                 185    



      <210> 1345
      <211> 279
      <212> PRT
      <213> Homo sapiens


      <400> 1345
 Met Ala Glu Ile Leu Leu Phe Cys Ser Leu Leu Cys Ser Gln Gly Leu
   1               5                  10                  15    
 Glu Gln Gly Phe Tyr Arg Trp Ser Asp Glu His Thr Thr Pro Ser Pro
              20                  25                  30        
 Ala Glu Pro Gly Lys Arg Gly Glu Leu Pro Gly Gln Phe Gly Ala Thr
          35                  40                  45            
 Phe Cys Leu Pro Asp Leu Val Arg Tyr Asp Gly His Ser Ala Ser Asn
      50                  55                  60                
 Ile Arg Glu Arg Arg Ala Arg Ile Ala Arg Gly Arg Trp Asp Arg Val
  65                  70                  75                  80
 Pro Asp Val Ala Thr Arg Arg Gly Leu Leu Leu Pro Ala Val Ser Gly
                  85                  90                  95    
 Lys Val Arg Gly Arg Arg Arg Pro Ser Asn Val Gly Phe Gly Asn Cys
             100                 105                 110        
 Glu Tyr Phe Thr Leu Arg Arg Ala Pro Ser Gly Asn Ala Thr Gln Asn
         115                 120                 125            
 Arg Gly Leu Leu Ser Pro Ala Gly Ala Ser Leu Pro Phe Ser Thr Arg
     130                 135                 140                
 Asn Lys Gln Pro Ala Val Pro Ala Ala Ala Gly Arg Ala Ala Glu His
 145                 150                 155                 160
 Ala Pro Gly Ala Gly Pro Gly Arg Asp Ser Gly Ala Gly Thr Ala Pro
                 165                 170                 175    
 Pro Ala Ser Ala Arg Gly Ile Val Arg Pro Pro Ser Ser Leu Ser Cys
             180                 185                 190        
 Arg Ala Arg Arg Arg Arg Arg Arg Arg Gly Glu Thr Arg Pro Phe Gly
         195                 200                 205            
 Gly Thr Ser Ser Pro Gly Arg Arg Gly Gly Ala Gly Arg Leu Ser Gln
     210                 215                 220                
 Arg Gly Gly Ser Ser Ala Ala Arg Pro Ala Gly Ser Ala Ala Ala Phe
 225                 230                 235                 240
 Glu Pro Pro Ser Gln Arg Gln Ser Pro Pro His Asn Ala Pro Arg Arg
                 245                 250                 255    
 Ala Ala Phe Glu Lys Ala Ala Arg Leu Val Gln Asp Gly Glu Leu Asp
             260                 265                 270        
 Gln Leu Pro Asp Glu Ser Glu
         275                



      <210> 1346
      <211> 199
      <212> PRT
      <213> Homo sapiens


      <400> 1346
 Met Thr Ala Phe Trp Phe Leu Leu Tyr Gly Ser Cys Gln Ile Val Ala
   1               5                  10                  15    
 Tyr Asn Ala Thr His Ala Val Glu His Glu Glu Leu Pro Gly Cys Arg
              20                  25                  30        
 Glu Gly Glu Pro Gly Gln Arg Pro Pro Arg Ser Val Thr Cys Leu Leu
          35                  40                  45            
 Glu Lys Ile Ser Ser Glu Val Gln Ala Val Leu Ser Leu Cys Pro His
      50                  55                  60                
 Pro Gln Ile Tyr Pro Leu Arg Arg Gln Phe Asp Ala Met Glu Thr Thr
  65                  70                  75                  80
 Gly Pro Leu Leu Val Asp Phe Glu Pro Ile Ala Leu Gln Val Leu His
                  85                  90                  95    
 Gln Asp Thr Ala Asn Val Lys Ala Ser Leu Gln Ala Leu Glu Glu Lys
             100                 105                 110        
 Ala Arg Arg Pro Ser Leu Glu Pro Lys Arg Leu Pro Pro Pro Thr Val
         115                 120                 125            
 Gln Thr Phe Pro His Ser Glu Ser Phe Gln Glu Gly Arg Cys Asn Gly
     130                 135                 140                
 Val Leu His Gln Asp Ile Ala Asn Val Gln Val Ser Leu Gln Glu Phe
 145                 150                 155                 160
 Gln Glu Lys Pro Arg Arg Pro Ser Leu Glu Pro Lys Pro Leu Pro Pro
                 165                 170                 175    
 Pro His Arg Ser Asp Leu Pro Pro Gln Pro Gly Phe Pro Glu Arg Ser
             180                 185                 190        
 Tyr Asn Gly Val Leu Arg Tyr
         195                



      <210> 1347
      <211> 398
      <212> PRT
      <213> Homo sapiens


      <400> 1347
 Met Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val
   1               5                  10                  15    
 Leu Ser Val Val Ser Val Leu Ser Val Val Asn Val Pro Ser Val Val
              20                  25                  30        
 Ser Val Pro Ser Leu Val Ser Val Pro Ser Leu Val Ser Met Leu Ser
          35                  40                  45            
 Val Phe Ser Val Leu Ser Val Cys Ala Leu Ser Met Val Ser Val Leu
      50                  55                  60                
 Ala Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val Val Asn
  65                  70                  75                  80
 Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val Phe Ser Val
                  85                  90                  95    
 Val Ser Val Phe Ser Val Val Ser Val Leu Ser Met Val Ser Val Leu
             100                 105                 110        
 Ser Met Asp Ser Val Leu Ser Val Val Ser Val Leu Ser Val Gly Ser
         115                 120                 125            
 Val Leu Ser Leu Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val
     130                 135                 140                
 Val Ser Val Leu Ser Leu Val Ser Val Leu Ser Val Val Ser Val Leu
 145                 150                 155                 160
 Ser Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Leu Val Ser
                 165                 170                 175    
 Val Leu Ser Val Val Ser Val Leu Ser Val Val Ser Val Leu Ser Val
             180                 185                 190        
 Val Ser Val Leu Ser Val Asp Ser Val Leu Ser Val Val Ser Val Leu
         195                 200                 205            
 Ser Val Val Ser Val Leu Ser Val Val Ser Val Phe Ser Val Val Ser
     210                 215                 220                
 Met Phe Pro Met Val Ala Leu Val Gln Trp Thr Glu Ser Val Gly Leu
 225                 230                 235                 240
 Thr Leu Val Ser Arg Asp Leu Thr Ser Met Gln Leu Lys Thr Pro Ser
                 245                 250                 255    
 Gly Gln Val Leu Ser Phe Cys Ile Leu Gln Leu Phe Pro Phe Thr Ser
             260                 265                 270        
 Glu Ser Lys Arg Met Gly Val Ile Val Arg Asp Glu Ser Thr Ala Glu
         275                 280                 285            
 Ile Thr Phe Tyr Met Lys Gly Ala Asp Val Ala Met Ser Pro Ile Val
     290                 295                 300                
 Gln Tyr Asn Asp Trp Leu Glu Glu Glu Cys Gly Asn Met Ala Arg Glu
 305                 310                 315                 320
 Gly Leu Arg Thr Leu Val Val Ala Lys Lys Ala Leu Thr Glu Glu Gln
                 325                 330                 335    
 Tyr Gln Asp Phe Glu Ser Arg Tyr Thr Gln Ala Lys Leu Ser Met His
             340                 345                 350        
 Asp Arg Ser Leu Lys Val Ala Ala Val Val Glu Ser Leu Glu Arg Glu
         355                 360                 365            
 Met Glu Leu Leu Cys Leu Thr Gly Val Glu Asp Gln Leu Gln Ala Asp
     370                 375                 380                
 Val Arg Pro Thr Leu Glu Met Leu Arg Asn Ala Gly Ile Lys
 385                 390                 395            



      <210> 1348
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1348
 Met Ala Trp Ser Thr Cys Gln Leu Leu Trp Arg Leu Cys Met Ser Cys
   1               5                  10                  15    
 Tyr Gly Asn Gln Ala Leu Ser Lys Lys Leu Glu Gln Ser His Trp His
              20                  25                  30        
 Ser Asn Cys Cys Ile Leu Asn Thr Gly Pro Asp Val Leu Glu Ala Leu
          35                  40                  45            
 Glu Ser Leu Ser Pro Ser Gly Val Asp Ser Gly Ser Met Val Ser Gly
      50                  55                  60                
 Gly Val Gly Gln Val Lys Arg Ser Ser Leu Tyr Val Ser Thr Ser Ser
  65                  70                  75                  80
 Gly Asn Ala Glu Gly Gly Ile Cys Glu Lys Ala Gln Pro Ser Asn Asn
                  85                  90                  95    
 Gly Ser Ser Lys Thr Asp Asn Lys Val Pro Phe Gly Tyr Thr Gln Arg
             100                 105                 110        
 Glu Lys Gln Leu Lys Thr Lys Thr Ser Val Gly Glu Lys Gln Arg
         115                 120                 125        



      <210> 1349
      <211> 207
      <212> PRT
      <213> Homo sapiens


      <400> 1349
 Met Pro Ala Leu Glu Thr Val Ala Gly Val Ala Val Leu Arg Trp Leu
   1               5                  10                  15    
 Ile Ser Asn Thr Ser Leu Met Val Arg Phe Arg Gly Ile Arg Ser Leu
              20                  25                  30        
 Leu Ala Arg Pro Gly Cys Tyr Val Pro Thr Ala Pro His Lys Leu Cys
          35                  40                  45            
 Tyr His Gly Ala Thr Ile Ala Gly His Val Pro Val Cys Pro Thr Leu
      50                  55                  60                
 Ala Trp Gly Gly Trp Pro Ser Thr Trp Glu Arg Leu Ser Thr Arg Ser
  65                  70                  75                  80
 Leu His Trp Thr Arg Ser Ala Pro Ala Ala Cys Pro Gly Thr Thr Leu
                  85                  90                  95    
 Val Thr Ile Phe Pro Phe Pro Gly His Trp Val Asp Asp Ala Lys Glu
             100                 105                 110        
 Leu Val Ala Gly Asp Gly Leu Gly Val Gln Val His Gly Asp Arg Leu
         115                 120                 125            
 Pro Leu Gln Val Leu Ile Gly Leu Val Glu Gly Phe Glu Asp Leu Ala
     130                 135                 140                
 Lys Ile Pro Ala Arg Ser Leu Glu Arg Val Thr His Leu Arg Phe Ala
 145                 150                 155                 160
 Ala Ala Arg Ile Pro Asp Asp Glu His Gly Val Ala Asp Leu Gln Gln
                 165                 170                 175    
 Leu Leu Gln Leu His His Leu Gln His Glu Ala Val Leu Arg Leu Gln
             180                 185                 190        
 Leu Glu Leu His Asp Ala Leu Leu Asp Asp Leu Gly Arg His Gly
         195                 200                 205        



      <210> 1350
      <211> 81
      <212> PRT
      <213> Homo sapiens


      <400> 1350
 Met Arg Arg Phe Arg Glu Leu Met Ser Leu Val Leu Val Leu Thr His
   1               5                  10                  15    
 Asp Ala Ser Asn Lys Asp Asn Arg Ala Ile Ser Val Ala Pro Glu Glu
              20                  25                  30        
 Gln Val Pro Ala Ser Ser Gln Asn Arg His Ser Ile Phe Ala Ala Ala
          35                  40                  45            
 Ser Glu Leu Trp Ala Arg Val Gln Lys Arg Gly Ala Gln Arg Pro Val
      50                  55                  60                
 Ser Ser Asn Thr Gly Trp Pro Pro Val Glu Asp Met Arg Met Thr Asp
  65                  70                  75                  80
 Ala
    



      <210> 1351
      <211> 84
      <212> PRT
      <213> Homo sapiens


      <400> 1351
 Met Leu Phe Pro Ala Ala Phe Ile Gly Leu Phe Val Phe Leu Tyr Gly
   1               5                  10                  15    
 Val Thr Thr Leu Asp His Ser Gln Val Ser Lys Glu Val Cys Gln Ala
              20                  25                  30        
 Thr Asp Ile Ile Met Cys Pro Val Cys Asp Lys Tyr Cys Pro Phe Met
          35                  40                  45            
 Arg Leu Ser Asp Ser Cys Val Tyr Ala Lys Val Ile Ser Asn Cys Ser
      50                  55                  60                
 Ile Leu Asp Glu Leu Asn Leu Thr Tyr Thr Phe Leu Arg Asp Glu Arg
  65                  70                  75                  80
 Ser Ser Val Phe
                



      <210> 1352
      <211> 284
      <212> PRT
      <213> Homo sapiens


      <400> 1352
 Met Gly Gln Val His Val Leu Leu Trp Leu Arg Lys Ala Phe Ile Leu
   1               5                  10                  15    
 Ser Pro Val His Tyr Pro Phe Lys Val Gln Asn Ser Lys Met Pro Glu
              20                  25                  30        
 Met Val Arg Arg Gly Leu Gly Gln Tyr Pro Glu His His His Gln Glu
          35                  40                  45            
 Ala Trp Lys Gln Leu Thr Val Pro Leu Asp Val Ala Cys Gly Pro Pro
      50                  55                  60                
 Glu Ile Ser Glu Arg His Arg Asp Val Trp Phe Asp Pro Glu Gln Phe
  65                  70                  75                  80
 Cys Asp Tyr Leu Val Ala Gly Pro Gly Ala Arg His Phe Pro Pro Pro
                  85                  90                  95    
 Ser Leu Val Phe Arg Leu Gln Asn Glu Asn Ser Cys Thr Tyr Phe Thr
             100                 105                 110        
 Gly Leu Ala Ala Glu Phe Asn Gly Pro Trp Arg Gln Gly Arg His Gln
         115                 120                 125            
 Glu Tyr Gln Glu Gln Leu Leu Pro Glu Arg Val Gly Gly Leu Gln Ser
     130                 135                 140                
 Pro Gln Lys Ser Leu Pro Asn Leu Phe Pro Ser Gly Phe Asn Ile Thr
 145                 150                 155                 160
 Leu Arg Trp Gly Gly Gly Arg Arg Gln Val Met Phe Thr Leu Leu Arg
                 165                 170                 175    
 Pro Glu Leu Pro Lys Gly Phe Asn Gln Ser Phe Glu Ser Ala Pro Gly
             180                 185                 190        
 Pro Glu Ser Gln Asn Asn Asn Gln Gly Ser Leu Pro Asp Leu Gln Gly
         195                 200                 205            
 Trp Asp Arg Lys Gln Ser Met Glu Val Ile Ala Met Ala Phe Pro Glu
     210                 215                 220                
 Glu Leu Glu Lys Asn Leu Gln Phe Arg Gly Glu His Trp Arg Leu Pro
 225                 230                 235                 240
 Lys Lys Leu Cys Gly Ser Glu Phe Thr Ala Lys Gln Lys Asp Pro Val
                 245                 250                 255    
 Gly Leu Pro Asp Ser Gly Leu Pro Thr Gly Asn Lys Glu Asp Arg Leu
             260                 265                 270        
 Ser Asp Arg Gly Ala Glu Glu Lys Arg Ile Gln Glu
         275                 280                



      <210> 1353
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 1353
 Met Ala Ala Ile Leu Val Pro Ser Ala Leu Ala Thr Val Leu Glu Val
   1               5                  10                  15    
 Leu Ala Arg Ala Ile Arg Gln Glu Lys Glu Ile Asn Gly Ile Gln Ile
              20                  25                  30        
 Ser Glu Glu Glu Val Lys Leu Leu Pro Phe Val Gly Asp Met Ile Val
          35                  40                  45            
 Tyr Leu Glu Asn Pro Lys Asp Ser Ser Arg Lys Leu Leu Glu Leu Ile
      50                  55                  60                
 Lys Glu Phe Ser Lys Val Ser Glu Tyr Lys Ile Asn Val Tyr Lys Ser
  65                  70                  75                  80
 Val Ala Leu Leu Tyr Thr Asn Ser Asp Gln Ala Glu Lys Gln Ile Lys
                  85                  90                  95    
 Asn Ser Ile Pro Phe Thr Ile Ala Ala Lys Ile Lys
             100                 105            



      <210> 1354
      <211> 345
      <212> PRT
      <213> Homo sapiens


      <400> 1354
 Met Leu Leu Leu Val Trp Gly Ser Val Ile Arg Val Gly Lys Ala Phe
   1               5                  10                  15    
 Arg Glu Asp Ser Gly Gly Leu Leu Phe Arg Glu Val Ala Pro Lys Lys
              20                  25                  30        
 Leu Leu Val Asp Cys Trp Cys Ser Glu Gly Glu Glu Val Lys Glu Glu
          35                  40                  45            
 Asp Lys Lys Glu Gln Pro Gln Leu Ser Gly Val Ala Pro Ser Ala Leu
      50                  55                  60                
 Pro Arg Cys Pro Asp Thr Arg Arg Trp Ala Ser Met Glu His Asn Thr
  65                  70                  75                  80
 His Ala Ala Pro Phe Thr Gly Glu Thr Thr Val Pro Glu His Val Trp
                  85                  90                  95    
 Ser Pro Ser Gln Val Lys Pro Leu Cys Ala Gly Thr Val Trp Pro Leu
             100                 105                 110        
 Thr Pro Ala Gly Thr Gly Val Cys Ser Gln Arg Asp Gln Gln Leu Lys
         115                 120                 125            
 Leu Arg Ser Leu Ala Thr Ala Gly Ser Pro Gln Thr His Gly Arg Thr
     130                 135                 140                
 Arg Ser Pro Ala Gly Thr Leu Trp Gly Gly Val Val Ser Arg Leu Phe
 145                 150                 155                 160
 Leu Tyr Asp Phe Gly Lys Gln Val Gly Gly Cys Gly Arg Pro Gln His
                 165                 170                 175    
 Arg Gly Thr Arg Val Ser Gln Leu Leu Leu Pro Met Ser Cys Ala Ala
             180                 185                 190        
 Pro Ala Pro Gly Ser Ile Leu Asn Pro Arg Ala Glu Pro Lys Gln Pro
         195                 200                 205            
 Asn Lys Gly Ala Gly Asp Ala Gly Leu Gln Gly Gly Ala Gln Gln Arg
     210                 215                 220                
 Lys Asp Arg Ala Ala Pro Arg Val Ser Pro Leu Thr Ile Ser Val Arg
 225                 230                 235                 240
 Lys Pro Arg Asp Gly Leu Gln Arg Glu Glu Glu Gln Gly Ala Val Leu
                 245                 250                 255    
 Arg Trp Lys Glu Arg Ala Pro Glu Leu Cys Ser Arg Ala Cys Ala Trp
             260                 265                 270        
 Pro Gly Val Asp Leu Ala Pro His Phe Ser Gly Ser Gly Arg Ala Leu
         275                 280                 285            
 Leu Met Ala Gln Asp Ser Leu Val Gln Gln His Ser Val Gln Val Gly
     290                 295                 300                
 Leu Gly Gln Thr Lys Arg Leu Pro Asp Gly Arg Leu Ala Ala Leu Leu
 305                 310                 315                 320
 Thr Ala Glu Ser Ala Ala Ala Ala Val Ser Arg Asp Gly Ser Gln Glu
                 325                 330                 335    
 Ser Leu Gln Gln Glu Gly Trp Cys Arg
             340                 345



      <210> 1355
      <211> 320
      <212> PRT
      <213> Homo sapiens


      <400> 1355
 Met Ser Leu Pro Ala Lys Leu Leu Cys Leu Leu Gln Ala Val His Ile
   1               5                  10                  15    
 Asp Pro Ala Leu Asp Gly His Gln Pro Arg Asp Gly Val Leu Val Gln
              20                  25                  30        
 Ser Gln Ala Ala Gln Val Asn Ser Arg Glu Gln Glu Phe Lys Gly Asn
          35                  40                  45            
 Ser His Ser Leu Thr Val Ser Leu Gln Leu Thr Thr Leu Ser Arg Asp
      50                  55                  60                
 Lys Gln Glu Gly Cys Gly Gly Phe Ser Gly Gly Asn Pro Ala Leu Tyr
  65                  70                  75                  80
 Ala Lys Tyr Leu Gln Cys Val Arg Ala Ala Gly Ser Glu Ile Asp Ala
                  85                  90                  95    
 Trp Asp Gly Asp Glu Gln Thr Thr Val Pro Thr His Leu Ile Ser Val
             100                 105                 110        
 Lys Trp Arg Val Gln His Val Ser Asn Thr Ala Ile Pro Thr Val His
         115                 120                 125            
 Tyr Val Gln Pro Gln Lys Thr Val Arg Gly Ile Asp Glu Glu Arg Pro
     130                 135                 140                
 Ile Pro Pro Trp Glu Thr Lys Asp Ser Phe Met Ile Glu Pro Leu Gly
 145                 150                 155                 160
 Val Gly Phe Arg Asn Leu His Leu His Ala Ala Arg Ile Phe Lys Glu
                 165                 170                 175    
 Leu Leu Pro Thr Glu Leu Pro Lys Gly Cys Gln Trp Val Gln Gln Leu
             180                 185                 190        
 Lys Ser Ser Glu Asp Ser Leu Glu Glu Pro Phe Gln Phe Lys His Val
         195                 200                 205            
 Phe Ile Leu Pro Leu Val Ile His Leu Ser Lys Thr His Gln Ile Ile
     210                 215                 220                
 Leu Asp Ala Leu Ser Ser Met Pro Ala Leu Gly Ser Phe Pro Pro Ser
 225                 230                 235                 240
 Gln Glu Ser Arg His Ala Met Lys Gly Tyr Leu Asn Ala Ile Glu Gln
                 245                 250                 255    
 Ser Trp Glu Ala Lys Ala Thr Ser His Ser Gly Ser Pro Phe Thr Arg
             260                 265                 270        
 Glu Lys Ser Val Glu Glu Glu Asp Trp Val Cys Phe Phe Leu Ile Lys
         275                 280                 285            
 Arg Gly Thr Asp Thr Leu Gly Pro Met Glu Ile Ile Thr Cys Phe Arg
     290                 295                 300                
 Asp Ala Glu Gly Ser Ile Ala Asn Arg Leu Phe His Pro Pro Pro Thr
 305                 310                 315                 320





      <210> 1356
      <211> 64
      <212> PRT
      <213> Homo sapiens


      <400> 1356
 Met Gln Gln Glu Ser Ala Ser His Leu Arg Thr Glu Arg Tyr Phe Leu
   1               5                  10                  15    
 His Gln Pro Leu Ala Leu Trp Lys Pro Ser Phe Ile Leu Phe Thr Gln
              20                  25                  30        
 Leu Leu Trp Ser Glu Leu Ser Ser Phe Val Asp His Thr Tyr Gly Asn
          35                  40                  45            
 Gln Glu Pro His Thr Val Ser Leu Tyr Gln Leu Gly Val Val His Lys
      50                  55                  60                





      <210> 1357
      <211> 124
      <212> PRT
      <213> Homo sapiens


      <400> 1357
 Met Asp Lys Arg Lys Ala Ser Gly Gly Pro Phe Pro Lys Pro Gln Pro
   1               5                  10                  15    
 Ile Thr Asn Phe Tyr Leu Cys Leu Arg Leu Phe Met Phe Phe Leu Ser
              20                  25                  30        
 Ile Pro Thr Pro Thr Pro Thr Ile Lys Ala Ser Met Gly Pro Ile Leu
          35                  40                  45            
 Phe Gly Asp Lys Phe Val Gly Thr His Leu Gln Leu Ser Gln Ile Pro
      50                  55                  60                
 Ala Arg Thr Leu Glu His Leu Gln His Asn Ala Pro Pro Val Thr Thr
  65                  70                  75                  80
 Arg Tyr Phe Leu Lys Glu Gln Glu Ser Glu Lys Ser Thr Ile Ser Glu
                  85                  90                  95    
 Ser Phe Lys Gln Cys Thr Cys Thr Ser Ile Cys Lys Gln Ile Ile Gln
             100                 105                 110        
 Lys Lys Ile Pro Thr Asn Cys Leu Ile Asn Cys Ser
         115                 120                



      <210> 1358
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1358
 Met Gly Lys Ala Met Leu Gln Leu Leu Ile Arg Ala His Trp Thr Val
   1               5                  10                  15    
 Phe Pro Cys Glu His Glu Asp Asn Ala Ala Ser Val Ser Val Thr Leu
              20                  25                  30        
 Cys Ser Asp Leu Ala Gly Gly Glu Val Val Ser Ala Val Leu Thr Gly
          35                  40                  45            
 Gln Ser Val Val Gln Thr Glu Lys Glu Ile Asp Arg Ser Ser Lys Pro
      50                  55                  60                
 Pro Ala Cys Leu Val Ala Pro Gln Val Val Phe Cys Ser Glu Val Leu
  65                  70                  75                  80
 Arg Val Asp Glu Ser Tyr His Arg Lys Tyr Pro Val Gln Leu Arg Pro
                  85                  90                  95    
 Val His Ile Ala Ala Lys
             100        



      <210> 1359
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 1359
 Met Val Lys Thr Gln Ile Cys Leu Leu Cys Ser His Phe Pro Phe Cys
   1               5                  10                  15    
 Gln Leu Asp Ile Glu Asp Ala Glu Gly Leu Glu Asp Asn Gly Ser Trp
              20                  25                  30        
 Val Lys Glu Val Trp Val Ser Glu Leu Leu His Glu Ala Val Pro Thr
          35                  40                  45            
 Leu Val Lys Lys Gly Thr Leu Phe Ser Ser Ser Cys Tyr Arg Ala Leu
      50                  55                  60                
 Arg Cys Thr Glu Leu Gln Gln Thr Gln Gly Ile Gln Gly Tyr Val Glu
  65                  70                  75                  80
 Lys Pro Leu Thr Thr Val Gln Gly Ala Glu Asp Ile Asn Asp Val Met
                  85                  90                  95    
 Ser Thr Gln Pro Ala Leu Arg Ile Leu Gln Glu Lys Asn Thr Glu Ile
             100                 105                 110        
 Thr Pro Asp Arg Trp Cys Phe Leu Ser Ser Ser Ile Lys Leu Ala His
         115                 120                 125            
 Gln Ala Arg Asn Phe Val Glu Glu Leu Ala
     130                 135            



      <210> 1360
      <211> 60
      <212> PRT
      <213> Homo sapiens


      <400> 1360
 Met Thr Gly Leu Arg Phe Phe Leu Glu Leu Phe Glu Thr Ala Thr Leu
   1               5                  10                  15    
 Gly Ala Val Phe Thr Ser Gly Ser Leu Phe Thr Val His Ala Gln Lys
              20                  25                  30        
 Pro Val Asp His Gly Leu Gly Ser Cys Lys Thr Ser Leu Lys Asp Arg
          35                  40                  45            
 Thr Trp Ser Leu Thr Arg Phe Val Cys Ile Ser Pro
      50                  55                  60



      <210> 1361
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 1361
 Met Cys Thr Thr Leu Phe Leu Leu Ser Thr Leu Ala Met Leu Trp Arg
   1               5                  10                  15    
 Arg Arg Phe Ala Asn Arg Val Gln Pro Glu Pro Ser Asp Val Asp Gly
              20                  25                  30        
 Ala Ala Arg Gly Ser Ser Leu Asp Ala Asp Pro Gln Ser Ser Gly Ser
          35                  40                  45            
 Gln Gly Gln Gly Pro Gly Glu Arg Thr Gly Trp Gln Pro Ala Ala Gln
      50                  55                  60                
 Leu Glu Met Arg Ser Leu Val Gln Ser Ala Ser Val Ser Lys Ala Gly
  65                  70                  75                  80
 Lys Gly Ser Ser Ser Ser His Gly Val Ala Ala Ala Leu Asn Gln Asp
                  85                  90                  95    
 Leu Asp Pro Asp Pro Lys Cys His Val Phe Asn His Ile Leu Leu Arg
             100                 105                 110        
 Ala Gln Ser Arg Ala Ser Phe Leu
         115                 120



      <210> 1362
      <211> 175
      <212> PRT
      <213> Homo sapiens


      <400> 1362
 Met Ala Leu Ser Ala Thr Leu Lys Leu Gln Ile Tyr Phe Leu Ala Gln
   1               5                  10                  15    
 Thr Thr Cys Asn Thr Leu Val Trp His Leu Ala Gly Cys Ala Cys Arg
              20                  25                  30        
 Thr Ala Gly Trp Leu Arg Ala Pro Ala Gln Trp Gly Trp Ala Leu Ala
          35                  40                  45            
 Thr Cys Ile Glu Ala Ala Leu Leu Asn Phe Ser Leu Thr Cys Phe Met
      50                  55                  60                
 Lys Val Asn Ser Ala Gly Thr Pro Arg Gly Ser Gly Glu Pro Thr Leu
  65                  70                  75                  80
 Pro Met Ile Gly Ala Leu Gly Trp His Ala Glu Phe Asn Gly Gly Ala
                  85                  90                  95    
 Arg Glu Arg Gly Met Pro Glu Asn Gln Gly Tyr Tyr Leu Ala Leu Val
             100                 105                 110        
 Gln Ser Phe Cys Ser Gln His Arg Pro Asp Ser Met Gln Asn Pro Leu
         115                 120                 125            
 Gln Thr Pro Glu Glu Val Gln Thr Arg Ser Val Pro Val Leu Met Val
     130                 135                 140                
 Leu His Glu Lys Val Gln Thr Arg Ser Val Pro Val Leu Met Val Leu
 145                 150                 155                 160
 His Glu Lys Ala Ser Asp Pro Thr Gly Ser Ile Gly Glu Ser Ala
                 165                 170                 175



      <210> 1363
      <211> 175
      <212> PRT
      <213> Homo sapiens


      <400> 1363
 Met Thr Lys Ala Leu Gly Ala Met Lys Ile Glu Ala Thr Leu Asp Ile
   1               5                  10                  15    
 Ser Ser Trp Ala Glu Arg Gly Ser Cys Ser Leu Ala Phe Leu Ile Pro
              20                  25                  30        
 Gln Leu Phe Pro Met Leu Thr Pro Cys Ser Lys Leu His Trp Leu Ser
          35                  40                  45            
 Leu Leu Leu Ala Trp Thr Ser Ile Ser Gln Tyr Ile Thr Gly Ser Leu
      50                  55                  60                
 Leu Glu Ala Thr Thr Ser Leu Gly Ala Arg Ser Gly Leu Leu Ser Thr
  65                  70                  75                  80
 Phe Gly Gly Ser Thr Gly Arg Met Met Leu Lys Ala Ser Ala Glu Glu
                  85                  90                  95    
 Met Thr Lys Tyr His Ser Asp Asp Tyr Ile Lys Ser Leu His Ser Ile
             100                 105                 110        
 His Pro Asp Asn Met Ser Glu Tyr Ser Gln Gln Ala Gln Arg Phe Asn
         115                 120                 125            
 Ile Gly Glu Asp Cys Pro Val Phe His Gly Leu Phe Glu Phe Arg Gln
     130                 135                 140                
 Leu Ser Val Gly Gly Ser Val Ala Ser Ser Val Lys Leu Asn Glu Trp
 145                 150                 155                 160
 Gln Thr Asp Ile Thr Met Asn Gln Thr Ala Pro Cys Lys Glu Val
                 165                 170                 175



      <210> 1364
      <211> 164
      <212> PRT
      <213> Homo sapiens


      <400> 1364
 Met Gly Trp Val Trp Gly Leu Val Arg Phe Thr Leu Glu Leu Phe His
   1               5                  10                  15    
 Thr Asp Asn Glu Glu Glu Gln Gln Tyr Ser Glu Val Thr Glu Glu Val
              20                  25                  30        
 Thr Glu His Val Tyr Leu Pro Ala Glu Ala Lys Ala Ala Lys Glu Gly
          35                  40                  45            
 Glu Phe His Pro Tyr Pro Ser Ala Ser Pro His Tyr Tyr Phe Glu Glu
      50                  55                  60                
 Asn Asp Ser Pro Asp Leu Ser Phe Pro Glu Asp Thr Gly Arg Lys Val
  65                  70                  75                  80
 Val Ala Pro Ala Gly Ile Gln Gln Ala Arg Gln Glu Gly Asp Leu Glu
                  85                  90                  95    
 Ala Trp Gln Phe Pro Val Arg Ile His Pro Pro Asp Gln Gln Gly Ser
             100                 105                 110        
 Ile Thr Ala Thr Phe Glu Pro Phe Pro Phe Lys Leu Leu Arg Glu Leu
         115                 120                 125            
 Lys Gln Ala Ile Asn Glu Tyr Gly Pro Gly Ser Pro Leu Val Ile Gly
     130                 135                 140                
 Leu Leu Lys Asn Val Thr Val Ser Ser Gln Met Ile Pro Thr Asp Trp
 145                 150                 155                 160
 Asp Ala Leu Thr
                



      <210> 1365
      <211> 276
      <212> PRT
      <213> Homo sapiens


      <400> 1365
 Met Met Leu Leu Leu Leu Ala Leu Leu Gly Ala Gly Leu Leu Gly Ala
   1               5                  10                  15    
 Ser Leu Leu Thr Ser Trp His Ala Pro Ala Arg Asn Lys Ile Pro Arg
              20                  25                  30        
 Ala Gln Lys Trp Arg Glu Glu Pro Asp Leu Asp Pro Lys Pro Ile Leu
          35                  40                  45            
 Glu Leu Pro Leu Ala Glu Leu Ala Gln Gln Leu Arg Thr Glu Glu Leu
      50                  55                  60                
 Ser Leu Glu Ser Ile Leu Cys Ser Tyr Leu Lys Gln Ala Leu Lys Val
  65                  70                  75                  80
 His Gln Glu Val Asn Cys Leu Met Asp Phe Leu Gly Glu Cys Glu Glu
                  85                  90                  95    
 Glu Leu Gln Ala Leu Lys Lys Leu Lys Lys Ser Glu Arg Gly Leu Leu
             100                 105                 110        
 Tyr Gly Val Pro Met Ser Leu Lys Asp Thr Tyr Asp Ser Met Phe Leu
         115                 120                 125            
 Glu Lys Pro Ala Thr Lys Asp Gly Val Ile Met Lys Val Leu Lys Ala
     130                 135                 140                
 Gln Gly Ala Ile Pro Phe Val Lys Thr Asn Ile Pro Leu Thr Leu Leu
 145                 150                 155                 160
 Arg Ser Leu Lys Arg Ala Ser Trp Ala Leu Asn Ala Ala Thr Pro Ile
                 165                 170                 175    
 Tyr Gly Gln Met Leu Ser Pro Leu Asn Leu Lys Lys Thr Cys Gly Gly
             180                 185                 190        
 Ser Ser Gly Val Thr Thr Val Ala Gly Pro Met Ala Gln Asp Val Glu
         195                 200                 205            
 Ser Leu Ala Leu Cys Leu Gln Ala Leu Leu Ser Glu Asp Met Tyr Arg
     210                 215                 220                
 Leu Asp Pro Thr Val Leu Gln Met Pro Phe Arg Glu Glu Val Tyr Thr
 225                 230                 235                 240
 Ser Asn Arg Pro Leu Arg Ile Gly Tyr Tyr Glu Ser Asp Gly Tyr Ile
                 245                 250                 255    
 Gln Pro Ser Pro Ser Met Ala Arg Ala Val Gln Leu Thr Ser Trp Leu
             260                 265                 270        
 Leu Gln Asp Ala
         275    



      <210> 1366
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1366
 Met Cys Arg Gly Lys Thr Phe Pro Ser Ile His Leu Trp Thr Arg Leu
   1               5                  10                  15    
 Leu Ser Ala Leu Ala Gly Leu Leu Tyr Ala Ser Ala Ile Val Ala His
              20                  25                  30        
 Asp Arg His Pro Glu Tyr Leu Leu Arg Ala Thr Pro Trp Phe Leu Thr
          35                  40                  45            
 Ser Leu Gly Arg Ala Ala Leu Asp Leu Ala Ile Ile Phe Leu Ser Cys
      50                  55                  60                
 Val Met Lys Ser Lys Met Arg Gln Ala Leu Gly Phe Ala Lys Glu Ala
  65                  70                  75                  80
 Arg Glu Ser Pro Asp Thr Gln Ala Leu Leu Thr Cys Ala Glu Lys Glu
                  85                  90                  95    
 Glu Glu Asn Gln Glu Val Arg Asn Glu Asp Lys Val Ser Leu Ala Gly
             100                 105                 110        
 Lys Leu Trp Ser Gln Gln Gln Tyr Leu Glu Lys Gln Gln Asp Thr Ala
         115                 120                 125            
 Asp Gly Arg Val Lys Ala Ala Cys Arg Val Phe Ser Ala Gly Asp Ser
     130                 135                 140                
 Asp Ser Cys Pro Val Ser Leu Arg Glu
 145                 150            



      <210> 1367
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1367
 Met Arg Ala Gly Ile Leu Val Cys Phe Val Tyr Gly Val Pro Leu Met
   1               5                  10                  15    
 Pro Pro Pro Asn Ala Ala Glu Lys Leu Ser Lys Val Lys Ala Lys Glu
              20                  25                  30        
 Glu Ser Trp Asp Ala Ile Val Gly Ser Glu Asp Tyr Glu Leu Asn Cys
          35                  40                  45            
 Val Pro Cys Ile Cys Glu Pro Ser Ala Val Leu Arg Leu Ala Ser Leu
      50                  55                  60                
 Lys Asp Ala Thr Gln Met Asn Asn Ala Val Pro Thr Ser Pro Leu Leu
  65                  70                  75                  80
 Gln Gln Met Gly His Pro His Ser Tyr Pro Asn Leu Gly Gln Ile Ser
                  85                  90                  95    
 Asn Pro Tyr Glu Gln Gln Pro Pro Gly Lys Glu Leu Asn Lys Tyr Ala
             100                 105                 110        
 Ser Leu Lys Ala Val Gly Ile
         115                



      <210> 1368
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1368
 Met Asn Leu Leu Glu Tyr Phe Leu Ala Leu Thr Ser Phe Ile Leu Arg
   1               5                  10                  15    
 Cys Ser Tyr Trp Ile Phe Pro Ser Ala Asn Asn Met Glu Val Pro Ile
              20                  25                  30        
 Gln Gly Gln Ile Ile Pro Gly Phe Ile Trp Ser Cys Leu Lys Val Lys
          35                  40                  45            
 Ser Leu Glu Phe Leu Met Ile Pro Phe Leu Tyr Gly Leu Gln Phe Asp
      50                  55                  60                
 Arg Trp Glu Phe Ser Thr Leu Lys Lys Thr Leu Ile Leu Met Ala Gly
  65                  70                  75                  80
 Gln Phe Gln Trp Ile Leu Ala Ser Leu Ser Gly Leu Arg Phe Cys Leu
                  85                  90                  95    
 Leu Phe Leu Gln Asn Asn Leu Gly Ser
             100                 105



      <210> 1369
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1369
 Met Val Val Cys Leu Leu Leu Arg Phe Cys Lys Thr His Gly Arg Ala
   1               5                  10                  15    
 Ile Leu Leu Tyr Ser Lys Ala Leu Arg Tyr Asp Gly Tyr Arg Thr Leu
              20                  25                  30        
 Cys Val Ala Phe Lys Glu Ile Ala Pro Asp Asp Tyr Glu Arg Ile Asn
          35                  40                  45            
 Ser Gln Leu Ile Glu Ala Lys Met Ala Leu Gln Asp Arg Glu Glu Lys
      50                  55                  60                
 Met Glu Lys Val Phe Asp Asp Ile Glu Thr Asn Met Asn Leu Ile Gly
  65                  70                  75                  80
 Ala Thr Ala Val Glu Asp Lys Tyr Leu Glu Asn Asp Thr Leu Ile Ile
                  85                  90                  95    
 Leu Met Thr Ser Val Leu Gly Lys Pro Glu Asp Pro Ser Cys Pro
             100                 105                 110    



      <210> 1370
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1370
 Met Gln Val Pro Ala Trp Leu Val His Cys Val Ile Phe Leu Ser Gln
   1               5                  10                  15    
 Ser Ile Asp Thr Glu Leu Lys Leu Asp Pro Leu Gly Thr Val Ser Arg
              20                  25                  30        
 Ile Phe Asp Ser Arg Arg Phe Gln Asp Met Asp Val Gly Pro Asn Ser
          35                  40                  45            
 Ile Ala Asn Lys Leu Ala Pro Pro Gly Arg Pro Thr Glu Arg Gly Gly
      50                  55                  60                
 Leu Phe Lys Cys Ser Val Pro Leu Arg Thr Val Arg Gly Cys Arg Ala
  65                  70                  75                  80
 Gly Leu Arg Gly Thr Glu Thr Val Pro Ser Ser Leu Gln Arg Gln Ala
                  85                  90                  95    
 Gly Trp Ser Arg Asp Leu Gly Ala Pro Ala Val Arg Thr Ala Pro Arg
             100                 105                 110        
 Glu Ser Arg Phe Gly Asn Phe Leu Glu His Leu Glu Leu
         115                 120                 125



      <210> 1371
      <211> 52
      <212> PRT
      <213> Homo sapiens


      <400> 1371
 Met Val Arg Lys Lys Ala Val Val Ser Ala Phe Gln Ser Trp Trp Val
   1               5                  10                  15    
 Leu Leu Gly Ile Phe Met Thr Lys Ile Glu Asn Val His Val Ala Glu
              20                  25                  30        
 Val Leu Pro Thr Gln Gly Thr Val Asp Ser Leu Gly Val Gln Ile Thr
          35                  40                  45            
 Glu His Val Pro
      50        



      <210> 1372
      <211> 216
      <212> PRT
      <213> Homo sapiens


      <400> 1372
 Met Asp Glu Arg Phe Asn Lys Trp Leu Leu Thr Pro Val Leu Thr Leu
   1               5                  10                  15    
 Leu Phe Val Val Ile Met Tyr Gln Tyr Val Ser Pro Ser Cys Thr Ser
              20                  25                  30        
 Ser Cys Thr Asn Phe Gly Glu Gln Pro Arg Ala Gly Glu Ala Gly Pro
          35                  40                  45            
 Pro Ala Val Pro Gly Pro Ala Arg Arg Ala Gln Ala Pro Pro Glu Glu
      50                  55                  60                
 Trp Glu Arg Arg Pro Gln Leu Pro Pro Pro Pro Arg Gly Pro Pro Glu
  65                  70                  75                  80
 Gly Pro Arg Gly Ala Ala Ala Pro Glu Glu Glu Asp Glu Glu Pro Gly
                  85                  90                  95    
 Asp Pro Arg Glu Gly Glu Glu Glu Glu Glu Glu Asp Glu Pro Asp Pro
             100                 105                 110        
 Glu Ala Pro Glu Asn Gly Ser Leu Pro Arg Phe Val Pro Arg Phe Asn
         115                 120                 125            
 Phe Ser Leu Lys Asp Leu Thr Arg Phe Val Asp Phe Asn Ile Lys Gly
     130                 135                 140                
 Arg Asp Val Ile Val Phe Leu His Ile Gln Lys Thr Gly Gly Thr Thr
 145                 150                 155                 160
 Phe Gly Arg His Leu Val Lys Asn Ile Arg Leu Glu Gln Pro Cys Ser
                 165                 170                 175    
 Cys Lys Ala Val Leu Thr Gln Ser Asp Pro Ala Leu Pro Ala Pro Ala
             180                 185                 190        
 Asp Gly Phe Leu Ala Ser Ser Ala Val Gly Ala Val Ala Leu Gly Arg
         195                 200                 205            
 Asp Glu Lys Pro Pro Asp Ser Ala
     210                 215    



      <210> 1373
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1373
 Met Arg Ala Pro Gln Gly Pro Ala Leu Phe Leu Leu Arg Leu Leu Arg
   1               5                  10                  15    
 Gly Trp Met Leu His Ala Pro Lys Ser Arg Lys Arg Arg His Pro Ala
              20                  25                  30        
 Phe Pro Ala Cys Ser Ile Gly Leu Pro Trp Thr Arg Arg Val Glu Gln
          35                  40                  45            
 Lys Glu Gln Arg Gly Arg Trp Glu Pro Trp Gly Val Arg Leu Ala Pro
      50                  55                  60                
 Glu Lys Leu Thr Ser Thr Cys Arg Lys Asn Cys Leu Phe Ser Leu Pro
  65                  70                  75                  80
 Cys Leu Glu Gln Ala Leu Leu Thr Asp His Ser Cys Trp Ala Gln Arg
                  85                  90                  95    
 Ser Leu Cys Thr Arg Asp Phe Arg Lys Leu Leu Leu Thr Tyr Gly Ser
             100                 105                 110        
 Trp Ser Gly Ser Ala Trp Ser Lys Leu Thr Thr Trp Ser Glu Gln Ile
         115                 120                 125            
 Gly Ala Phe Ala Phe Pro Ser Ser Thr Asn Thr Gly His Val Asp Thr
     130                 135                 140                
 Ser Glu Gly Arg Ala Lys Arg Ala Pro Gly Arg Gly Arg Val His Thr
 145                 150                 155                 160
 Phe Thr Lys Gln Ile Val Arg Lys Arg Ile Glu Ser Lys Ser Glu Ala
                 165                 170                 175    
 Thr Trp Lys Leu Glu Glu Asn Thr Pro Gly Phe Val Gln His Gly Pro
             180                 185                 190        
 Ala Leu Met Gln Gly Glu Gly Ala Val Arg Asn Arg Asp Cys Ser Phe
         195                 200                 205            
 Ser Leu Asp Pro Thr Ala Lys Lys Pro His Gly Thr Glu Leu Gln Leu
     210                 215                 220                
 Thr
 225



      <210> 1374
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 1374
 Met Val Ala His Glu Val Gly Val Leu Ala Ala Leu Thr Ala Leu Gln
   1               5                  10                  15    
 Val Val Ser Gly Asp Gly Glu Gly His Leu Cys Gly Val Gln Gly Ala
              20                  25                  30        
 Leu Gln Pro Leu Leu Leu Gly Gln Glu Gln Val Gly Leu Arg Ser Gln
          35                  40                  45            
 Arg Leu His Leu Thr Leu Gln Leu Arg Leu Pro Ala Val Arg Val Leu
      50                  55                  60                
 Gln Ser Leu Ala His Cys Ala Arg Gly Val Leu Leu Arg Ala Leu Arg
  65                  70                  75                  80
 Gln Arg Leu Gly Leu Cys Gly Gln Leu Leu Ala Leu Val Pro Leu Pro
                  85                  90                  95    
 Leu Arg Leu Val Ala Val Gly Glu Gly Leu Val Val Ala Ser Ile Ala
             100                 105                 110        
 Val Leu Glu Pro Leu Leu Gln Gln Gly Gly Gly Arg Ser Cys Ala Ala
         115                 120                 125            
 Glu Ala Ala Leu Lys Ala Ile Gln Gly Gln Ala Ala Trp Arg Arg Leu
     130                 135                 140                
 Asp Gly Gln Glu Ala Pro Gln Asp Thr Ser Glu Ser Pro
 145                 150                 155        



      <210> 1375
      <211> 365
      <212> PRT
      <213> Homo sapiens


      <400> 1375
 Met Ser Leu Trp Lys Lys Thr Val Tyr Arg Ser Leu Cys Leu Ala Leu
   1               5                  10                  15    
 Ala Leu Leu Val Ala Val Thr Val Phe Gln Arg Ser Leu Thr Pro Gly
              20                  25                  30        
 Gln Phe Leu Gln Glu Pro Pro Pro Pro Thr Leu Glu Pro Gln Lys Ala
          35                  40                  45            
 Gln Lys Pro Asn Gly Gln Leu Val Asn Pro Asn Asn Phe Trp Lys Asn
      50                  55                  60                
 Pro Lys Asp Val Leu Glu Pro Gln Phe Arg Gln Phe Leu Phe Tyr Arg
  65                  70                  75                  80
 His Cys Arg Tyr Phe Pro Met Leu Leu Asn His Pro Glu Lys Cys Arg
                  85                  90                  95    
 Gly Asp Val Tyr Leu Leu Val Val Val Lys Ser Val Ile Thr Gln His
             100                 105                 110        
 Asp Arg Arg Glu Ala Ile Arg Gln Thr Trp Ala Arg Ala Ala Val Arg
         115                 120                 125            
 Gly Trp Gly Pro Ser Ala Val Arg Thr Leu Phe Leu Leu Gly Thr Ala
     130                 135                 140                
 Ser Lys Gln Glu Glu Arg Thr His Tyr Gln Gln Leu Leu Ala Tyr Glu
 145                 150                 155                 160
 Asp Ala Leu Tyr Gly Asp Ile Leu Gln Trp Gly Phe Leu Asp Thr Phe
                 165                 170                 175    
 Phe Asn Leu Thr Leu Lys Glu Ile His Phe Leu Lys Trp Leu Asp Ile
             180                 185                 190        
 Tyr Cys Pro His Val Pro Phe Ile Phe Lys Gly Asp Asp Asp Val Phe
         195                 200                 205            
 Val Asn Pro Thr Asn Leu Leu Glu Phe Leu Ala Asp Arg Gln Pro Gln
     210                 215                 220                
 Glu Asn Leu Phe Val Gly Asp Val Leu Gln His Ala Arg Pro Ile Arg
 225                 230                 235                 240
 Arg Lys Asp Asn Lys Tyr Tyr Ile Pro Gly Ala Leu Tyr Gly Lys Ala
                 245                 250                 255    
 Ser Tyr Pro Pro Tyr Ala Gly Gly Gly Gly Phe Leu Met Ala Gly Ser
             260                 265                 270        
 Leu Ala Arg Arg Leu His His Ala Cys Asp Thr Leu Glu Leu Tyr Pro
         275                 280                 285            
 Ile Asp Asp Val Phe Leu Gly Met Cys Leu Glu Val Leu Gly Val Gln
     290                 295                 300                
 Pro Thr Ala His Glu Gly Phe Lys Thr Phe Gly Ile Ser Arg Asn Arg
 305                 310                 315                 320
 Asn Ser Arg Met Asn Lys Glu Pro Cys Phe Phe Arg Ala Met Leu Val
                 325                 330                 335    
 Val His Lys Leu Leu Pro Pro Glu Leu Leu Ala Met Trp Gly Leu Val
             340                 345                 350        
 His Ser Asn Leu Thr Cys Ser Arg Lys Leu Gln Val Leu
         355                 360                 365



      <210> 1376
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 1376
 Met Ser Leu Leu Gly Ala Cys Thr Ser Arg Leu Cys Thr Leu Cys Gly
   1               5                  10                  15    
 Ala His Ala Gly Ser Ala Pro Ala Ala Leu Pro Gly Pro Gln Leu Trp
              20                  25                  30        
 Ile His Arg Ser Leu Ser Ser Met Ala Leu Gln Asp Thr Arg Glu Glu
          35                  40                  45            
 Leu Pro Lys Thr Ala Ala Pro Leu Gln Thr Leu Ser Asp Gly Pro Cys
      50                  55                  60                
 Thr Ser Ala His Ser Thr Glu Cys Asp Gln Leu Trp Ser Ser Ile Gln
  65                  70                  75                  80
 Asn Gly Pro Leu Leu Ala Gly Pro
                  85            



      <210> 1377
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1377
 Met Leu Leu Gly Pro Arg Ser Thr Tyr Thr Gly Met His Ser Leu Arg
   1               5                  10                  15    
 Arg Ala Thr Leu Val Leu Leu Leu Met Thr Val Thr Arg Arg Phe Glu
              20                  25                  30        
 Lys Asn Asp Arg Gly Gly Ala Asp Glu Thr Thr Glu Gln Asp Gly Ile
          35                  40                  45            
 Ile Phe Lys Ser Glu Cys Phe Glu Asp Leu Gly Ala Glu Glu Arg Leu
      50                  55                  60                
 Ala Asn Arg Ser Gln Thr Leu Leu
  65                  70        



      <210> 1378
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 1378
 Met Leu Ser Met His Leu Leu His Ser Phe Asn Val Tyr Leu Trp Gly
   1               5                  10                  15    
 His Leu Leu Tyr Ile Pro Leu Tyr Ala Ser Tyr Ile Pro Val Leu Ser
              20                  25                  30        
 Asn Lys Arg Met Asp Lys Ala Arg Arg Gly Thr Lys Asn Val Leu Arg
          35                  40                  45            
 Lys Lys Ser Phe Leu Thr Glu Thr Arg Thr Lys Glu Arg Arg Phe Pro
      50                  55                  60                
 Ser Thr Ile His Ala His Asn Gln Ala Leu Cys Lys Pro Leu Tyr Leu
  65                  70                  75                  80
 Ile Gln Ser Leu Gln Leu Tyr His Lys Gly Phe Val Lys Ile Gln Arg
                  85                  90                  95    
 Val His Ala
            



      <210> 1379
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 1379
 Met Arg Leu Phe Leu Ser Leu Pro Val Leu Val Val Val Leu Ser Ile
   1               5                  10                  15    
 Val Leu Glu Glu Val Ser Asn Pro Phe Asp Gly Leu Glu Glu Leu Gly
              20                  25                  30        
 Lys Thr Leu Glu Asp Tyr Thr Arg Glu Phe Ile Asn Arg Ile Thr Gln
          35                  40                  45            
 Ser Glu Leu Pro Ala Lys Met Trp Asp Trp Phe Ser Glu Thr Phe Arg
      50                  55                  60                
 Lys Val Lys Glu Lys Leu Lys Thr Asp Ser
  65                  70                



      <210> 1380
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1380
 Met Ala Arg Cys Leu Gly Gln Gly Ala Pro Gly Val Trp Ala Val Leu
   1               5                  10                  15    
 Leu Ala Ala Ile Asn Gln Trp Ser Thr Glu His Ala Leu Lys Ile Trp
              20                  25                  30        
 Leu Gln Lys Tyr Ile Tyr Trp Tyr Gly Glu Cys Ser Arg Tyr Ile Ser
          35                  40                  45            
 Glu Lys Ser Cys Cys Val Ala Leu Ser Tyr Arg Lys Leu Glu Lys Asn
      50                  55                  60                
 Pro Glu Lys Glu Glu Glu His Trp Ala Arg Leu Gln Arg Tyr Ser Leu
  65                  70                  75                  80
 Ser Leu Gln Arg Glu Asn Phe Lys Lys
                  85                



      <210> 1381
      <211> 116
      <212> PRT
      <213> Homo sapiens


      <400> 1381
 Met Arg Glu Tyr Gly Arg Ala Leu Lys Leu Arg Val Leu Pro Leu Val
   1               5                  10                  15    
 Cys Val His Gly Gln Glu Ala Gly Ala Pro Trp His Thr Gly Gly Gln
              20                  25                  30        
 Val His Asp Val Leu Gln Tyr Gly Ile Ile Ala Glu Glu Asn Lys Asn
          35                  40                  45            
 Leu Gln Pro Gln Gly Asp Glu Asp Pro Gly Lys Phe Lys Glu Ala Glu
      50                  55                  60                
 Leu Lys Met Arg Lys Gln Phe Gly Met Pro Glu Gly Glu Lys Leu Val
  65                  70                  75                  80
 Asn Tyr Tyr Ser Cys Ser Tyr Trp Lys Gly Arg Val Pro Arg Gln Gly
                  85                  90                  95    
 Trp Leu Tyr Leu Thr Val Asn His Leu Cys Phe Tyr Ser Phe Leu Leu
             100                 105                 110        
 Gly Lys Glu Arg
         115    



      <210> 1382
      <211> 259
      <212> PRT
      <213> Homo sapiens


      <400> 1382
 Met Val Phe Asp Ser Pro Gln Glu Ala Ala Val Ile Ser Leu Leu Phe
   1               5                  10                  15    
 Ala His Trp Leu Gly Met Cys Ser Ser Ala Ala Gly Ile Pro Leu Ala
              20                  25                  30        
 Ser Ser Ser Thr Ser Met Gln Arg Lys Glu Glu Gln Gln Arg Gly Cys
          35                  40                  45            
 Ile Ser Arg Ile Ala Trp Pro Leu Arg Pro Glu His Pro Ser Pro Ser
      50                  55                  60                
 Leu Leu Glu Asn Val Pro Ser Ala Ala Gly Ser Gly Gly Lys Arg Gly
  65                  70                  75                  80
 Thr Thr Ile Glu Arg Ala Ser Ser Asn Thr Ser Pro Thr Trp His Arg
                  85                  90                  95    
 Tyr Ser Leu Arg Thr Asn Ser His Pro Lys Gly Lys Arg Gly Pro Val
             100                 105                 110        
 Gln Ser Ser Val Val Cys Pro Pro Leu His Gln Tyr Ser His Leu Ile
         115                 120                 125            
 Gln Arg Gly Thr Ala Asn Leu Gly Leu Gln Ala Ser Pro Leu Leu Leu
     130                 135                 140                
 Thr Gln Val Thr Glu Leu Arg Leu Pro Ile Leu Thr Ala Ala Arg Arg
 145                 150                 155                 160
 Phe His Ala Asp Pro Val Gly Met Gly Val Ser Ala Leu Ile Pro Leu
                 165                 170                 175    
 Cys Ile Leu His Glu Trp Leu Asp Phe His Gly Leu His Ser Ala Lys
             180                 185                 190        
 Asp Ser Cys Ala Glu Ser Tyr Gly Thr Ala Asp Leu Pro Ile Asn Gln
         195                 200                 205            
 His Asp Leu Leu Arg Arg Arg Ala Arg Leu Arg Arg Lys Arg Thr Gln
     210                 215                 220                
 Ala Arg Leu Val Gly Trp Asn Pro Ser Cys Ala Ala Glu Gln Leu Glu
 225                 230                 235                 240
 His Val Thr Gln Pro Pro Pro Asn Val Arg Lys Ala His Ser Pro Val
                 245                 250                 255    
 Pro Arg Thr
            



      <210> 1383
      <211> 401
      <212> PRT
      <213> Homo sapiens


      <400> 1383
 Met Ala Leu Ser Lys Ala Thr Gln Pro Ala Gly Thr Met Leu Ser Ile
   1               5                  10                  15    
 Leu Leu Asn Ala Ser Leu Ala Ser Gln Ala Phe Ser Gly Met Asp Ala
              20                  25                  30        
 Pro Leu Phe Glu Cys Glu Val Phe Glu Ala Gly Ala Ala Gln Leu Ser
          35                  40                  45            
 Asp Ser Arg Arg Gly Leu Leu Thr Gly Pro Leu Pro Arg Leu Leu Ala
      50                  55                  60                
 Gln Phe Thr Val His Ser Pro Val Ala Pro Leu Asn Pro Cys Arg Phe
  65                  70                  75                  80
 Pro His His Arg Leu Pro Leu Asp Trp Leu Pro Thr Ser Gln Asn Arg
                  85                  90                  95    
 Gly Arg Glu Glu Thr Ser Ala Met Met Gln Ala Arg Asn Ala Lys Leu
             100                 105                 110        
 Pro Asp Ile Met Trp Leu Thr Gln Gly His Pro Thr Met Ala Leu Ala
         115                 120                 125            
 Phe Leu Ser Ala Trp Phe Asp Leu Leu Ile Pro Pro Gly Glu Asn Val
     130                 135                 140                
 Thr Val Lys Gly Gly Val Gln Glu Ala Ser Gly Thr Gln Arg Gly Leu
 145                 150                 155                 160
 Ser Gly Tyr Thr Ile Arg His Arg Arg Ser Leu Gly Ser Glu Cys Leu
                 165                 170                 175    
 Arg Ser His Asn Lys Cys Pro Glu Glu Ala Glu Phe Lys Gly Cys Cys
             180                 185                 190        
 Pro Gly Ser Ala Ser Cys Ala Leu Phe Gln Gly Ser Ala Ser Asp Val
         195                 200                 205            
 Gln Thr Gln Ser Ser His His Pro Val Val Gln Gly Thr Val Phe Glu
     210                 215                 220                
 Ala Met Lys His Gln Lys Ala Arg Trp Ser Tyr Val Leu Lys Ala Gly
 225                 230                 235                 240
 Arg Cys Thr Glu Gln Gln Leu Ile Ile Arg Leu Glu Thr Leu Ala Gly
                 245                 250                 255    
 Pro Leu Ala Gln Cys Pro Pro Pro Ala Pro Pro Ala Glu Asn Arg Met
             260                 265                 270        
 Trp Val Ser Gly Ala Pro Ala Ala Phe Pro Ala Ser Pro Asp Cys Val
         275                 280                 285            
 Gln Gly Asp Lys Gly Ala Asp Glu Arg Glu Ile Ser Gly Gly Thr Asp
     290                 295                 300                
 Thr Ala Ala Ala Glu Glu Glu Thr Asp Ala Leu Gly Ser Ser Ser Gln
 305                 310                 315                 320
 Ala Trp Asn Pro Gly Pro Trp Thr Pro Lys Pro Trp Gly Ser Pro Met
                 325                 330                 335    
 Gly Gln Trp Ala Thr Leu Thr Leu Thr Leu Ser Ser Leu Ala Thr Gln
             340                 345                 350        
 Thr Thr Pro Gly Leu Val Lys Ala Val Ile Pro Leu Thr Arg Glu Leu
         355                 360                 365            
 Gly Ile Phe Arg Leu Ala Arg Lys Lys Glu Asn Arg Gly Gln Ser Val
     370                 375                 380                
 Ser His Leu Ser Met Pro Gly Glu Thr Gly Ala Pro His Val His Val
 385                 390                 395                 400
 Lys
    



      <210> 1384
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1384
 Met Ala Cys Pro Gln Leu Pro Pro Leu Leu Leu Leu Val Leu Val Val
   1               5                  10                  15    
 Leu Leu Lys Ala Gly Val Asn Tyr Asn Thr Pro Phe Thr Gly Asp Thr
              20                  25                  30        
 Gly Pro Arg Glu Leu His Arg Asn Pro Ser Val Val Val Val Val Cys
          35                  40                  45            
 Leu Leu Val Ser Leu Leu Leu Ile Gly Ser Val Val Met Ala Val Arg
      50                  55                  60                
 Phe Cys His Arg Asn Glu Ser Lys Phe Glu Asn Leu Asp Glu Val Ser
  65                  70                  75                  80
 Met Trp Phe Trp Glu Leu Val Asp Ser Gly Leu Ala Pro Val Ser Pro
                  85                  90                  95    
 Leu Gly Gly Gly Ile Ile Arg Arg Gly Phe Ser Gly Thr Pro Leu Leu
             100                 105                 110        
 Pro Ser Leu Pro Ser Arg Leu Val Leu Pro Gly Glu Val Glu Pro Ser
         115                 120                 125            
 Thr His Val Val Phe Thr Ile Glu Ala
     130                 135        



      <210> 1385
      <211> 257
      <212> PRT
      <213> Homo sapiens


      <400> 1385
 Met Leu Thr Leu Trp Arg Gln Leu Phe Phe Phe Leu Gln Phe Phe Lys
   1               5                  10                  15    
 Lys Tyr Leu Thr Pro Glu Lys Arg Ala Asp Met Ile Met Val Ser Met
              20                  25                  30        
 Glu Ala Met Thr Asn Thr Ser Arg Arg Asp Ile Ser Ala Ala Ser Lys
          35                  40                  45            
 Met Leu Lys Met Ile Leu Lys Tyr Thr Ile Pro Glu Ile Gly Lys Val
      50                  55                  60                
 Leu Glu Ile Ile Gln Tyr Ile His Tyr His Met Asn Ser Ile Thr Glu
  65                  70                  75                  80
 Thr Thr Ala Gln Lys Thr Ile Lys Lys Ile Leu Tyr Leu Leu Ser Gln
                  85                  90                  95    
 Tyr Tyr Thr Glu Val Ile Leu Thr Ala Thr Arg Ala Ile His Glu Leu
             100                 105                 110        
 Leu Leu Glu Pro Ser Arg Gln Met Glu Val Gln Ser Phe Phe Ser Ser
         115                 120                 125            
 Leu Phe Met Ala Leu Leu Phe Gln Ile Ser Phe Leu Val Val Glu Gly
     130                 135                 140                
 Asp Ala Glu Thr Ser Arg Asp Gln Gln His Ile Ala Glu Trp Met Asp
 145                 150                 155                 160
 Pro Ile Ser Ser Thr Met Glu Ala Leu Lys Thr Leu Ile Gln Ser Ser
                 165                 170                 175    
 Gly Tyr Gly Asp Cys Val Ser Ser Ile Gln Arg His Gly Val Trp Gly
             180                 185                 190        
 Leu Leu Val Asn Pro Glu Arg His Tyr Gly Gly Val Thr Leu Pro Ala
         195                 200                 205            
 Arg Ser Val Val Ile Asn Asn Cys Trp His Asn Arg Pro Leu Phe Ser
     210                 215                 220                
 Ser Ile Ile Arg Phe Leu Gln Asp Pro Asp Leu Gln Glu Ser Leu Asn
 225                 230                 235                 240
 Gly Pro Cys Val Pro Asp Arg Gly Asp Trp Leu Leu Ala Gly Gly Gly
                 245                 250                 255    
 Arg
    



      <210> 1386
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1386
 Met Trp Gly His Ser Cys Ala Leu Arg Val Gln Ala Pro Leu Val Leu
   1               5                  10                  15    
 Leu Gln Val Pro Phe Trp Leu Val Asp Thr Gln Met Thr Ala Pro Arg
              20                  25                  30        
 Ala Gly Val Gly Met Pro Arg Leu Pro Pro Ala Pro Gly Pro Leu Ser
          35                  40                  45            
 Thr Thr Val Ile Pro Gly Ala Ala Pro Thr Leu Ser Val Pro Thr Pro
      50                  55                  60                
 Gly Gln Val Gly Gln Leu Gly Ala Gln Gly Ser Trp Asn Thr Pro Gln
  65                  70                  75                  80
 Val Pro Val Leu Pro Val Phe Leu Gln Pro Pro Val Val Ser Met Pro
                  85                  90                  95    
 Gly Pro Arg Leu Arg Ile Thr
             100            



      <210> 1387
      <211> 297
      <212> PRT
      <213> Homo sapiens


      <400> 1387
 Met Pro Leu Pro Leu Ile Arg Leu Val Pro Ser Gly Val Arg Leu Leu
   1               5                  10                  15    
 Gln Asn Ala Phe Phe Val Ala Gln Arg Pro Ser Val Ser His Gln Lys
              20                  25                  30        
 Cys Asn Gly Arg Ile Gly Leu Met Glu Pro Leu Ala Val Ala Pro Gly
          35                  40                  45            
 Pro Phe Phe Lys Pro Ile Phe Arg Pro His Pro Leu Lys Ile Arg Glu
      50                  55                  60                
 Phe Gln Gly Arg Gly His Gln Ala Arg Val Asn Phe Ala Gly Glu Lys
  65                  70                  75                  80
 Leu His Arg Ala Cys Cys Gly Arg Gly Arg Leu Cys Arg Glu His Arg
                  85                  90                  95    
 Val Leu Ala Leu Pro Leu Ser Ser Thr Leu Pro Tyr Arg Asp Cys Ala
             100                 105                 110        
 Pro Gly Cys Ile Leu His Phe Pro Pro Phe Val His Arg Tyr Glu Val
         115                 120                 125            
 Asp Asp Ile Asp Glu Glu Gly Lys Ala Arg His Thr Val Ser Leu Arg
     130                 135                 140                
 Arg Ile Ile Pro Leu Thr Arg Trp Lys Ala Asn Pro Glu Thr Asp Pro
 145                 150                 155                 160
 Glu Ala Leu Leu Val Lys Glu Lys Thr Met Phe Ser Gly Cys Cys Asp
                 165                 170                 175    
 Leu Gly Asp Ser Thr Ala Asn Thr Gly Ser Leu Gly Ile His Leu Val
             180                 185                 190        
 Thr Glu Leu Ile Gln Ala Lys Arg Ser Pro Val Gly Thr Phe Pro Phe
         195                 200                 205            
 Glu Asn Met Cys Lys Gly Pro Lys Gly Tyr Arg Pro Leu Ala Ser Pro
     210                 215                 220                
 Gly Ser Leu Gly Lys Pro Gln Val Ser Gly Phe Pro Ser Ala Ala Pro
 225                 230                 235                 240
 Gly Glu Pro Ala Leu Arg Gln Glu Ala Pro Ala Leu Asn Pro Arg Leu
                 245                 250                 255    
 Leu Pro Pro His Ala Pro Gly Asp Met Gly His Lys Pro Pro Glu Ala
             260                 265                 270        
 Arg Ile Pro Ala Cys His His Leu Gly Cys Pro Arg Ser Ser Glu His
         275                 280                 285            
 Arg Val Pro Glu Arg Gln Gln Thr Leu
     290                 295        



      <210> 1388
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1388
 Met Lys Thr Leu Leu Ala Arg Ala Ser Arg Phe Leu Ala Leu Pro Arg
   1               5                  10                  15    
 Thr Ser Phe Asn Ala Leu Ser Lys Ser His Asn Leu Leu Gly Phe Lys
              20                  25                  30        
 Asp Ile Arg Ser Asn Val Glu Ala Leu Ala Gln Lys Thr Gln Pro Ser
          35                  40                  45            
 Val Phe Pro Lys Glu Ser Val Gln Val Thr Pro Val Cys Tyr Thr Lys
      50                  55                  60                
 Gly Asp Arg Glu Ser Val Gln Lys Cys Pro Leu Ile Phe Arg Ser His
  65                  70                  75                  80
 Ser Ala Thr Glu Gln Val Ser Ile Arg Arg Gly Val Ile Val Arg Val
                  85                  90                  95    
 Ala Lys Trp Arg Gly Glu Ser His Ile His Gly Gly Pro Asp Val Pro
             100                 105                 110        
 Gly Leu Val Leu Asp Thr Ser Tyr Glu Thr Ser Pro Leu Ile His Thr
         115                 120                 125            
 Pro Ala Leu Arg Val Tyr Tyr Ile Gly Glu Asp Ile Ala Met Glu Gln
     130                 135                 140                
 Val Thr Asn Leu Ala Phe Pro Leu Leu Tyr Ser Asn Ser His Arg Val
 145                 150                 155                 160
 Ser Glu Pro Gly Glu Leu Gly Phe Trp Gly Pro Gly Glu Ser Val Met
                 165                 170                 175    
 Pro Ala Asp Ala Val Ser Val Pro Cys Thr Cys His Pro Gly Ser Tyr
             180                 185                 190        
 Gly Val Gln Pro Leu Val Leu Arg Ile Gln Gly Tyr Ser Gly Thr Gly
         195                 200                 205            
 Arg Trp Ile Ser Ala Ser Ala Met Ser Cys Ile Ile Ser Asp Arg Asn
     210                 215                 220                
 Gly
 225



      <210> 1389
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 1389
 Met Lys Phe Leu Ala Val Leu Val Leu Leu Gly Val Ser Ile Phe Leu
   1               5                  10                  15    
 Val Ser Ala Gln Asn Pro Thr Thr Ala Ala Pro Ala Asp Thr Tyr Pro
              20                  25                  30        
 Ala Thr Gly Pro Ala Asp Asp Glu Ala Pro Asp Ala Glu Thr Thr Ala
          35                  40                  45            
 Ala Ala Thr Thr Ala Thr Thr Ala Ala Pro Thr Thr Ala Thr Thr Ala
      50                  55                  60                
 Ala Ser Thr Thr Ala Arg Lys Asp Ile Pro Gly Thr Ala Leu Met Glu
  65                  70                  75                  80
 Ser Leu Leu Leu Gln Ser Thr Val Leu Cys Ser Met Met Gly Leu Gly
                  85                  90                  95    
 Glu Lys Leu Gln Val Val Val Asn Asp Asp Lys Arg Gly Phe Trp Val
             100                 105                 110        
 Ser Pro Pro Pro Ser Gln Pro Pro Pro Tyr Cys Val Pro Ser Ser Pro
         115                 120                 125            
 Ser Leu Leu Ser Ser Ser Leu Val His Met Phe Leu Asp Leu Ile Tyr
     130                 135                 140                
 Phe Cys Thr Leu Cys Gly Cys Ala Thr Val Gly Pro
 145                 150                 155    



      <210> 1390
      <211> 104
      <212> PRT
      <213> Homo sapiens


      <400> 1390
 Met Leu Arg Ala Leu Ile Phe Ser Asp Asn Leu Ile Met Phe Ile Val
   1               5                  10                  15    
 Leu Ile Val Tyr Lys Phe Ile Gly Ala Ile Asn Met Pro Val Leu Ser
              20                  25                  30        
 Val Pro Glu Lys Ser Val Val Gly Ile Lys Phe Asn Gly Ala Ala Lys
          35                  40                  45            
 Gly Glu Gln Gln Glu Glu Ala Gly Thr Cys Ser Asp Cys Gln Ile Leu
      50                  55                  60                
 Val Ala Pro Ser Gly Leu Leu Pro Arg Pro Pro Ser Leu Gln Pro Arg
  65                  70                  75                  80
 Leu Leu Met Arg Ile Gly Leu Gln Ser Gly Leu Ser Ser Gly Ser Ser
                  85                  90                  95    
 Pro Asp Gly Ser Leu His Trp Leu
             100                



      <210> 1391
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 1391
 Met Trp Leu Leu Gly Pro Leu Cys Leu Leu Leu Ser Ser Ala Ala Glu
   1               5                  10                  15    
 Val Leu Thr His Gly Ser Tyr Gly Asp Lys Ile Leu Pro Ala Asn Glu
              20                  25                  30        
 Met Arg Arg Leu Ile Asn Phe Glu Leu Gly Leu Val Ser Leu Thr Pro
          35                  40                  45            
 Val Ala Ala Gln Gly Glu Ser Ala Gly Gly Asn Leu Gln Glu Gln Leu
      50                  55                  60                
 Arg Ala Ser His Met Asp Gly Lys Arg Met
  65                  70                



      <210> 1392
      <211> 128
      <212> PRT
      <213> Homo sapiens


      <400> 1392
 Met Ala Arg Ala Leu Cys Arg Leu Pro Arg Arg Gly Leu Trp Leu Leu
   1               5                  10                  15    
 Leu Gly Gly Arg Pro Gln Gly Thr Gly Glu Ala Glu Gly Ala Asp Arg
              20                  25                  30        
 Cys Cys Ala Ser Arg Arg Gly Arg Asp Gly Phe Gly Asp Val Gly Glu
          35                  40                  45            
 Arg Ala Phe Trp Lys Ala Trp Gly Glu Ser Ala Leu His Thr Gly Glu
      50                  55                  60                
 Leu Val Phe Arg Arg Lys Asn Arg Thr Arg Gly Ser Pro Ala Pro His
  65                  70                  75                  80
 Leu Val Ser Gln Ala Val Arg Arg Gly Asp Cys Gln Arg Arg Leu Pro
                  85                  90                  95    
 Ser Leu Gly Arg Pro Ala Leu Gln Asn Leu Gln Thr Gly Thr Leu Gln
             100                 105                 110        
 Lys Thr Gln Cys Ser Gly Ile Arg Thr Thr Ala Gly Leu Tyr Gly Asn
         115                 120                 125            





      <210> 1393
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1393
 Met Pro Phe Leu Ala Cys Leu Ser Phe Ala Asp Leu Leu Phe Lys Ser
   1               5                  10                  15    
 Leu Pro Glu Asn Ala His Thr Leu Val Phe Ser Phe Leu Leu Pro Ser
              20                  25                  30        
 Ser Leu Tyr Phe Phe Ile Arg Asn Ile Thr Val His Asp Gly Ser Leu
          35                  40                  45            
 Pro Gly Asn Leu Ala Cys Ser Gln Asp Trp Arg Phe Thr Pro Arg Leu
      50                  55                  60                
 His Leu
  65    



      <210> 1394
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1394
 Met Val Arg Pro Lys Thr Lys Lys Lys Phe Leu Leu Ser Leu Glu Lys
   1               5                  10                  15    
 Tyr Ser Glu Thr Asn Phe Thr Leu Leu Arg Val Cys Phe Leu Phe Leu
              20                  25                  30        
 Leu Leu Leu His Gly Gly Gly Thr Gly Gln Arg Lys Glu Glu Glu Pro
          35                  40                  45            
 Ala Phe Leu Gly Thr Arg Lys Ala Thr Gly Gln Ala Arg Gly Ser Ser
      50                  55                  60                
 Met Phe Pro Asn Ser His Arg Trp Gln Ile Thr Phe Pro Gln Ala Gln
  65                  70                  75                  80
 Arg Arg Glu Asn Tyr Pro Leu Lys Glu Thr Glu Arg Ser Phe Asn Thr
                  85                  90                  95    
 Lys Gln Gly Arg Glu Phe Gln Lys Leu Pro Leu Val Ser Glu Ala Phe
             100                 105                 110        
 Tyr Cys Gln His Thr Phe Arg Val Asn Leu Lys Val Gly Ile Tyr Thr
         115                 120                 125            
 Arg Leu Glu Ile Lys Ser Arg Leu Asp
     130                 135        



      <210> 1395
      <211> 218
      <212> PRT
      <213> Homo sapiens


      <400> 1395
 Met Trp Leu Gln Ala Val Ser Leu Gln Leu Met Ile His Leu Thr Ala
   1               5                  10                  15    
 Arg Gly Thr Asp Glu Ile Lys Ala Gln Arg Arg Ala Ser Cys Asp Gln
              20                  25                  30        
 Leu Pro Ala Lys Phe Pro Ala Leu Gly Leu Ser Lys Cys Leu Leu Leu
          35                  40                  45            
 Glu Glu Ala Gln Ala Lys Thr Trp Glu Thr Asp Ser Pro Gly His Asp
      50                  55                  60                
 Val Thr Lys Val Ala Pro Cys His Ser Gln Leu Tyr Ser His Gln Leu
  65                  70                  75                  80
 Ser Asn Pro Arg Glu Lys Gly Ala Pro Ile Ser Asn Cys Phe Arg Thr
                  85                  90                  95    
 Arg Lys Ser Lys Arg His Pro Leu Cys Cys Tyr Leu Leu Leu Pro Pro
             100                 105                 110        
 His Gln Leu Thr Cys Phe His Leu Pro Tyr Ile Pro Asn Trp Asn Ala
         115                 120                 125            
 His Pro Thr Met His Ser Ser Pro Ala Ala Ser Pro Phe Gly Pro Gly
     130                 135                 140                
 Ile Glu Asp Thr Ile Leu Ile Ile Pro Pro Ser Gly Pro Ala Ser Ser
 145                 150                 155                 160
 Lys Thr Arg Ser Asp Gly Asn Lys Leu Ala Thr Leu Asn Ala Ile Val
                 165                 170                 175    
 Asn Val Thr Asn Val Asp Lys Glu Ser Phe Gln Lys Pro Lys Arg Asp
             180                 185                 190        
 Thr Glu Glu Ser Leu Lys Pro Ala Gly Asn Val Gly Thr Leu Phe Arg
         195                 200                 205            
 Asn Cys Gly Gln Val Pro Gln Glu Lys Lys
     210                 215            



      <210> 1396
      <211> 366
      <212> PRT
      <213> Homo sapiens


      <400> 1396
 Met Gly Pro Ala Trp Val Gln Asp Pro Leu Thr Gly Ala Leu Trp Leu
   1               5                  10                  15    
 Pro Val Leu Trp Ala Leu Leu Ser Gln Val Tyr Cys Phe His Asp Pro
              20                  25                  30        
 Pro Gly Trp Arg Phe Thr Ser Ser Glu Ile Val Ile Pro Arg Lys Val
          35                  40                  45            
 Pro His Arg Arg Gly Gly Val Glu Met Pro Asp Gln Leu Ser Tyr Ser
      50                  55                  60                
 Met His Phe Arg Gly Arg Arg His Val Ile His Met Lys Leu Lys Lys
  65                  70                  75                  80
 Asn Met Met Pro Arg His Leu Pro Val Phe Thr Asn Asn Asp Gln Gly
                  85                  90                  95    
 Ala Met Gln Glu Asn Tyr Pro Phe Val Pro Arg Asp Cys Tyr Tyr Asp
             100                 105                 110        
 Cys Tyr Leu Glu Gly Val Pro Gly Ser Val Ala Thr Leu Asp Thr Cys
         115                 120                 125            
 Arg Gly Gly Leu Arg Gly Met Leu Gln Val Asp Asp Leu Thr Tyr Glu
     130                 135                 140                
 Ile Lys Pro Leu Glu Ala Phe Ser Lys Phe Glu Tyr Val Val Ser Leu
 145                 150                 155                 160
 Leu Val Ser Glu Glu Arg Pro Gly Glu Val Ser Arg Cys Lys Thr Glu
                 165                 170                 175    
 Gly Glu Glu Ile Asp Gln Glu Ser Glu Lys Glu Ser Leu Val Arg Gly
             180                 185                 190        
 Asn Ile Met Asn Gly Phe His Lys Phe His Met Ile Pro Gln Leu Phe
         195                 200                 205            
 Leu His Gln Ile Asp Leu Glu Thr Val Ser Val Met Pro Ala Leu Thr
     210                 215                 220                
 Glu Tyr Ala Thr Pro Thr Gly Glu Gln Ser Pro Arg Cys Gly Asp Asn
 225                 230                 235                 240
 Ile Lys Asn Gln Arg Glu Glu Cys Asp Cys Gly Ser Leu Lys Asp Cys
                 245                 250                 255    
 Ala Ser Asp Arg Cys Cys Glu Thr Ser Cys Thr Leu Ser Leu Gly Ser
             260                 265                 270        
 Val Cys Asn Thr Gly Leu Cys Cys His Lys Cys Lys Tyr Ala Ala Pro
         275                 280                 285            
 Gly Val Val Cys Arg Asp Leu Gly Gly Ile Cys Asp Leu Pro Lys Tyr
     290                 295                 300                
 Cys Asp Gly Lys Lys Glu Glu Cys Pro Asn Asp Ile Tyr Ile Gln Asp
 305                 310                 315                 320
 Gly Thr Pro Cys Ser Ala Val Ser Val Cys Ile Arg Gly Asn Cys Ser
                 325                 330                 335    
 Asp Arg Asp Met Gln Cys Gln Ala Leu Phe Gly Tyr Gln Val Lys Asp
             340                 345                 350        
 Gly Ser Pro Ala Cys Tyr Gln Lys Leu Asn Arg Ile Gly Asn
         355                 360                 365    



      <210> 1397
      <211> 186
      <212> PRT
      <213> Homo sapiens


      <400> 1397
 Met Val Ala Val Arg Cys Ala Phe Val Phe Leu Gly Val Phe Val Arg
   1               5                  10                  15    
 Ser Val Ala Leu Pro His Pro Glu Gly Glu Leu His Arg Gly Met His
              20                  25                  30        
 Arg Ala Leu Leu Ser Ala Ala Asp Arg Gly Pro Asp Gln Pro Arg Val
          35                  40                  45            
 Arg Lys Asp Phe Gln Ala Leu Glu Pro Ser Gly Gly Gly Lys Gln Arg
      50                  55                  60                
 Arg Ser Val Pro Val Ser Asp Pro Arg Arg Ala Leu Leu Gly Ser Asn
  65                  70                  75                  80
 Leu Glu Pro Ser Gly Phe Arg Ser Gln Glu Lys Ser Pro Pro Asn Cys
                  85                  90                  95    
 Asp Pro Pro Asn Cys Asp Gln Gly Ser Ala Ile Ala Arg Phe Ser Leu
             100                 105                 110        
 Pro Asp Leu Gly Thr Gln Glu Arg Pro Arg Gln Pro Gln Pro Arg Gly
         115                 120                 125            
 Gly Ser Val Pro Gly Pro Gln Ser Gly Gln Leu Ser Pro Ser Gly Asn
     130                 135                 140                
 Arg Gly Tyr Glu Asn Phe Arg Leu Trp Gly Pro Val Pro Met Lys Glu
 145                 150                 155                 160
 Asn Phe Pro Glu Gly Val Arg Thr Lys Glu Ser Arg Ser Phe Ser Gly
                 165                 170                 175    
 Leu Ile Ala Lys Met Met Arg Thr Phe Arg
             180                 185    



      <210> 1398
      <211> 86
      <212> PRT
      <213> Homo sapiens


      <400> 1398
 Met Lys Val Ser Leu Val Thr Leu Ala Arg Val Val Leu Leu Phe Met
   1               5                  10                  15    
 Val Asp Asn Gly Ala Asp Asp Trp Arg Ile Ala Met Thr Tyr Glu Arg
              20                  25                  30        
 Ile Phe Phe Ile Cys Leu Glu Ile Leu Val Cys Ala Ile His Pro Ile
          35                  40                  45            
 Pro Gly Asn Tyr Thr Phe Thr Trp Thr Ala Arg Leu Ala Phe Ser Tyr
      50                  55                  60                
 Ala Pro Ser Thr Thr Thr Ala Asp Tyr Leu Ile Met Asp Asn Cys Arg
  65                  70                  75                  80
 Met Asp Cys Pro Ser Leu
                  85    



      <210> 1399
      <211> 445
      <212> PRT
      <213> Homo sapiens


      <400> 1399
 Met Leu Phe Val Gln Ala Leu Leu Ser Gly Leu Phe Ser Thr Pro Leu
   1               5                  10                  15    
 Asn Pro Leu Leu Gly Ser Ala Val Phe Ile Met Ser Tyr Ala Arg Pro
              20                  25                  30        
 Leu Lys Phe Trp Glu Arg Asp Tyr Asn Leu Leu Ile Cys Leu His Asn
          35                  40                  45            
 Gly Ala Val Leu Asp Gly Val Asp Leu Val Ala Gln Gly Glu His Glu
      50                  55                  60                
 Gln Val His Pro Leu Phe Thr Phe Leu Ala Asn Arg Leu Val Ala Leu
  65                  70                  75                  80
 Ser Leu Asn Ser Thr Lys Arg Val Asp His Ser Asn Thr Arg Leu Val
                  85                  90                  95    
 Thr Gln Leu Asp Arg Asn Pro Ala His Thr Val Trp Gly Pro Gly Ala
             100                 105                 110        
 Gly Pro Leu Gly Asn Tyr Gly Pro Gly Asp Cys Phe Val Leu Ala Ser
         115                 120                 125            
 Asp Tyr Leu Asn Ala Leu Val His Leu Ile Glu Val Gly Asn Gly Leu
     130                 135                 140                
 Val Thr Phe Gln Leu Arg Gly Leu Glu Phe Arg Gly Glu Pro Gln Asp
 145                 150                 155                 160
 Gln Ala Arg Arg Trp Leu Ala Trp Glu Val Thr Ala Ser Lys Tyr Val
                 165                 170                 175    
 Leu Glu Gly Tyr Ser Ile Ser Asp Asn Asn Ala Ala Ser Met Leu Gln
             180                 185                 190        
 Val Phe Asp Leu Arg Lys Ile Leu Ile Thr Tyr Tyr Val Lys Ser Ile
         195                 200                 205            
 Ile Tyr Tyr Val Ser Arg Ser Pro Lys Leu Glu Val Trp Leu Ser His
     210                 215                 220                
 Glu Gly Ile Thr Ala Ala Leu Arg Pro Val Arg Val Pro Ala Met Pro
 225                 230                 235                 240
 Thr Ser Asp Pro Thr Phe Ser Leu Ser Val Asp Glu Asp Tyr Asp Leu
                 245                 250                 255    
 Arg Leu Ser Gly Leu Ser Leu Pro Ser Phe Cys Ala Val His Leu Glu
             260                 265                 270        
 Trp Ile Gln Tyr Cys Ala Ser Gln Arg Ser Leu Glu Pro Phe Leu Tyr
         275                 280                 285            
 Gly Leu His Ala Leu Phe Lys Gly Asp Phe Arg Ile Thr Ser Pro Arg
     290                 295                 300                
 Asp Glu Trp Val Phe Ala Asp Met Asp Leu Leu His Arg Val Val Ala
 305                 310                 315                 320
 Pro Gly Val Arg Met Ala Leu Lys Leu His Gln Asp His Phe Thr Ser
                 325                 330                 335    
 Pro Asp Glu Tyr Glu Glu Pro Ala Ala Leu Tyr Asp Ala Ile Ala Ala
             340                 345                 350        
 Asn Glu Glu Arg Leu Val Ile Ser His Glu Gly Asp Gln His Gly Ala
         355                 360                 365            
 Ala Pro Ser Ser Ala Thr Arg Pro Pro Cys Trp Leu Arg His Val Leu
     370                 375                 380                
 Asp Asp Ala Ser Asp Glu Tyr Lys Ile Ile Met Leu Asn Arg Arg His
 385                 390                 395                 400
 Leu Ser Phe Arg Val Ile Lys Val Asn Arg Glu Cys Val Arg Gly Leu
                 405                 410                 415    
 Trp Gln Ser Val Ser Glu Leu Val Phe Leu Arg Asn Arg Asn Pro Glu
             420                 425                 430        
 Arg Gly Ser Ile Gln Asn Ala Lys Gln Ala Phe Ala Thr
         435                 440                 445



      <210> 1400
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1400
 Met Ala Cys Tyr Leu Leu Val Ala Asn Ile Leu Leu Val Asn Leu Leu
   1               5                  10                  15    
 Ile Ala Val Phe Asn Asn Thr Phe Phe Glu Val Lys Ser Ile Ser Asn
              20                  25                  30        
 Gln Val Trp Lys Phe Gln Arg Tyr Gln Leu Ile Met Thr Phe His Glu
          35                  40                  45            
 Arg Pro Val Leu Pro Pro Pro Leu Ile Ile Phe Ser His Met Thr Met
      50                  55                  60                
 Ile Phe Gln His Leu Cys Cys Arg Trp Arg Lys His Glu Ser Asp Pro
  65                  70                  75                  80
 Asp Glu Arg Asp Tyr Gly Leu Arg Thr Leu Ala Asn Val Glu Glu His
                  85                  90                  95    
 Gly Ile Gln Asn Gln Gly Gln Arg Asp Ala Leu Met Asn Asp Ser Leu
             100                 105                 110        
 Gln Trp Ile Thr Cys
         115        



      <210> 1401
      <211> 406
      <212> PRT
      <213> Homo sapiens


      <400> 1401
 Met Gly Leu Ala Gln Glu Leu Asp Trp Ser Phe Ala Lys Val Ala Ser
   1               5                  10                  15    
 Ser Cys Trp Lys Thr Gln Ala Ser Trp Cys Ile Ser Phe Leu Lys Leu
              20                  25                  30        
 Thr Pro Gly Trp Leu Gly Arg Gly Gly Val Leu Leu Leu Ala Pro Ala
          35                  40                  45            
 Gln Trp Leu Pro Thr Ala Ile Thr Leu Ser Leu Ala Thr Ala Asp Phe
      50                  55                  60                
 Ser Met Ala Val Ser Met Ala Thr Gly Val His Gly Lys Cys Leu Arg
  65                  70                  75                  80
 Ser Pro Phe Ser Asn Glu Cys Gly Val Gln Val Leu Cys Leu Asp Ala
                  85                  90                  95    
 Glu Leu Gly Thr Pro Pro Cys Arg Pro Asn Ser Phe Met Leu Val Arg
             100                 105                 110        
 Glu Ser Lys Thr Leu Trp Glu Gly Ile Gln Pro Asp Ala Gln Pro Asp
         115                 120                 125            
 Gly Pro His Ala Pro Ala Leu Arg Gln Gln Thr Leu Gln Val Pro Leu
     130                 135                 140                
 Leu Pro Lys Gln Ile His Pro Glu Gly Glu Pro Asp Thr Pro His Glu
 145                 150                 155                 160
 Ser Gln Ala Trp Ser His Gly Ala Gly Pro Ser Phe Pro Ser Val Pro
                 165                 170                 175    
 Pro Ile Pro Gly Gly Leu Thr Ile Gly Ser Ser Lys Val Lys Ala Leu
             180                 185                 190        
 Lys Thr Gly Ser Asn Glu Thr Ala Met Leu Lys Ser Pro Ser Leu Gln
         195                 200                 205            
 Pro Cys Lys Leu Lys Ala Lys His Phe Leu Arg Cys Met Asn Ser Tyr
     210                 215                 220                
 Ser Ala Leu Ala Gly Leu Gly Arg Gly Arg Ile Ala Leu Ala Gln Thr
 225                 230                 235                 240
 Ala Gly Val Leu Arg Ser Leu Glu Gln Glu Glu Pro Phe Asp Leu Ser
                 245                 250                 255    
 Gln Lys Arg Arg Ala Lys Val Pro Val Phe Gln Ser Asp Gly Glu Ser
             260                 265                 270        
 Ala Gln Gly Ser His Cys His Glu Glu Glu Glu Glu Asp Asn Cys Tyr
         275                 280                 285            
 Glu Val Glu Pro Tyr Ser Pro Gly Leu Ala Pro Gln Ser Gln Gln Leu
     290                 295                 300                
 Cys Thr Pro Glu Asp Leu Ser Thr Lys Ser Glu His Ala Pro Glu Val
 305                 310                 315                 320
 Leu Glu Glu Ala Cys Lys Glu Glu Lys Glu Asp Ala Ser Lys Gly Glu
                 325                 330                 335    
 Trp Glu Lys Arg Ser Lys Gly Asp Leu Gly Ala Glu Gly Gly Gln Glu
             340                 345                 350        
 Arg Asp Cys Ala Gly Arg Asp Glu Cys Leu Ser Leu Arg Ala Phe Gln
         355                 360                 365            
 Ser Thr Arg Arg Gly Pro Ser Phe Ser Asp Tyr Leu Tyr Phe Lys His
     370                 375                 380                
 Arg Asp Glu Ser Leu Lys Glu Leu Leu Glu Arg Lys Met Glu Lys Gln
 385                 390                 395                 400
 Ala Val Leu Leu Gly Ile
                 405    



      <210> 1402
      <211> 387
      <212> PRT
      <213> Homo sapiens


      <400> 1402
 Met Pro Ala Val Leu Ser Ala Ile Pro Asn Thr Trp Leu Val Leu Ser
   1               5                  10                  15    
 Ile Cys Ile Pro Ser His Ser Val Pro Gly Pro Gly Ser Ser Lys Ala
              20                  25                  30        
 Ala Ser Pro Phe Pro Pro Ala Leu Leu Ala Pro Cys Arg Ser Thr Ser
          35                  40                  45            
 Gly His Arg His Leu Ser Pro Ser Leu Ala Arg Thr Thr Lys Pro Leu
      50                  55                  60                
 Ser Ser Thr Lys Gly Thr Arg Ser Ser Gln Pro Tyr Met Ala Pro Ile
  65                  70                  75                  80
 Ile Ile Leu Ser Ala Gly Ser Pro Ala Leu Asn His Leu Tyr Met Cys
                  85                  90                  95    
 Ile Ala Gly Cys Gln Gln Met Ile His Glu Thr Gln Gln Thr Asp Ala
             100                 105                 110        
 Leu Val Gly Thr Gly Asn Arg Arg Ile Glu Arg His Gly Gly Ile Arg
         115                 120                 125            
 Cys Lys Asn Gln Arg Ala Trp Ala Val Asp Ser Gly Ser Asn Tyr Asp
     130                 135                 140                
 Gln Gly His Glu Val Gln Gln Ile Pro Arg Leu Gly Glu Ile Lys Ala
 145                 150                 155                 160
 Trp Phe Trp His Ile Asp Ile Thr Phe Ser Lys Ser Arg Phe Ser Asp
                 165                 170                 175    
 Ser Leu Gln Thr Tyr Trp Ile Arg Pro Ser Lys Gly Gly Ala Gln Pro
             180                 185                 190        
 Ser Val Leu Gln Gly Ala Leu Gln Arg Pro Ser Leu Cys Val Ala Ser
         195                 200                 205            
 Gly Glu Phe Val Gly Arg Gly Leu His Asn Trp Gly Leu Leu Arg Asp
     210                 215                 220                
 Ser His Pro Met Thr Ile Trp His Ser Ser Glu Leu Glu Leu Pro Cys
 225                 230                 235                 240
 Ile Phe Ser Gln Glu Glu Glu Glu Gly Gly Thr Thr Pro Pro Ser Ala
                 245                 250                 255    
 Gln Asn Ile Gly Ile Glu Trp Arg His Asn Lys Arg Leu Ser Pro Gly
             260                 265                 270        
 Ser Asn His Lys Met Ile Lys His Phe His Ser Lys Cys Arg Thr Glu
         275                 280                 285            
 Thr Val Met Thr Glu Glu Glu Glu Trp Lys Pro Met Asp Pro Ser Lys
     290                 295                 300                
 Met Arg Cys Ser Phe Phe Gln Asn Gly Lys Glu Ser Glu Lys Glu Lys
 305                 310                 315                 320
 Val Pro Thr Arg Ser Leu Leu Ala Gln Val Ile Ile Pro Leu Val Asn
                 325                 330                 335    
 Tyr Arg Cys Phe Leu Gln Gln Leu Leu Phe Arg Ala Leu Ser Cys Tyr
             340                 345                 350        
 Gln Arg Val His Cys Asn Gln Ile Phe Pro Ala Glu Arg His Gly His
         355                 360                 365            
 Tyr Gly Leu Ser Thr Phe Pro Gly Met Ala Leu Leu Gly Gln Leu Trp
     370                 375                 380                
 Glu Lys Gly
 385        



      <210> 1403
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1403
 Met Ser Gly Phe Glu Val Phe Ala Phe Phe Phe Tyr Cys Ile Phe Ala
   1               5                  10                  15    
 Ser Leu Ser Ile Tyr Gly Tyr Arg Lys Leu Ile Leu Gly Val Glu Glu
              20                  25                  30        
 Gln Met Phe Cys His Cys His Ile Leu Leu Asp Thr Asp Trp Arg Thr
          35                  40                  45            
 Ile Gly Met Tyr Val Glu Glu Ser Thr His Ile Leu Ser Ser Glu His
      50                  55                  60                
 Phe Asp Gly Ile Asn His Lys Leu His Ala Arg Thr Ile Cys Phe Thr
  65                  70                  75                  80
 Lys Ala Tyr Leu Lys Ser Thr Ala Asn Gly Tyr Tyr Phe Thr Glu
                  85                  90                  95



      <210> 1404
      <211> 284
      <212> PRT
      <213> Homo sapiens


      <400> 1404
 Met Ala Leu Arg Arg Leu Gly Ala Ala Leu Leu Leu Leu Pro Leu Leu
   1               5                  10                  15    
 Ala Ala Val Glu Gly Met Ala Glu Leu Ala Gly Gln Glu Ala Asn Val
              20                  25                  30        
 Asn Asn Gly Ser His Val Tyr Cys Thr Leu Gln Phe Ser Asn His Phe
          35                  40                  45            
 Thr Val Tyr Glu Val Leu Arg Thr Ile Arg Ser Ser Leu Trp Phe Thr
      50                  55                  60                
 Thr Cys Cys Thr Val Asp Lys Pro Lys Lys Lys Arg Ile Ser Asp Gln
  65                  70                  75                  80
 Thr Trp Gly Leu Arg Pro Leu Gly Lys Ala Ser Trp Gly Thr Leu Cys
                  85                  90                  95    
 Tyr Asn Phe Ser Phe Ser Phe Gly Asn Glu His Phe Ser Asp Arg Ser
             100                 105                 110        
 Gln Gly Val Gly Gly Val Pro Gly Trp Gln Pro Gln Phe Leu Ala Leu
         115                 120                 125            
 Arg Gln Leu Ser Phe Gly Ser Trp Gly Ile Trp Arg Leu Thr Ala Val
     130                 135                 140                
 Ser Arg Ser Gly Ala Thr Gly Ala Pro Arg Val Pro Arg Ala Leu Gly
 145                 150                 155                 160
 Val Glu Gly Ser Pro Gly Ala Trp Leu Leu Ala Gly Ala Leu Trp Asn
                 165                 170                 175    
 Met Ala Glu Leu Phe Glu Pro Gln Leu Leu Glu Leu Tyr Asn Glu Val
             180                 185                 190        
 Arg Gln Gly Val Leu Glu Glu Ala Thr Ser Lys Met Ile Leu Lys Glu
         195                 200                 205            
 Glu Pro Gly Glu Glu Ala Ala Arg Gln Pro Phe Gln Ala Thr Gly Thr
     210                 215                 220                
 Ala Ser Ala Lys Ile Arg Ile Gly Gly Pro Gly Pro Glu Leu Ala Ser
 225                 230                 235                 240
 Leu Gln Ile Arg Leu His Asp Ser Ser Gln Trp Pro Ala Gly Gly Val
                 245                 250                 255    
 Phe Ser Arg Leu Pro Asp Gly Ile Cys Pro Lys Met Gly Lys Pro Arg
             260                 265                 270        
 Pro Lys Glu Asp Lys Asp Leu Cys Lys Val Thr Gln
         275                 280                



      <210> 1405
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1405
 Met Arg Thr Trp Arg Lys Gly Ser Pro Ala Glu Leu Ser Phe Ala Leu
   1               5                  10                  15    
 Leu Pro Leu Leu Gly Pro Gln His Leu Cys Pro Glu Pro Leu His Pro
              20                  25                  30        
 Pro Ala Leu Ser Gly Ser Ser Ser Phe Ala Ser Arg Ala Pro Trp Gly
          35                  40                  45            
 Asp Glu Ala Ala Ser Val Ala Ser Val Thr Ser Leu Lys Val Leu Val
      50                  55                  60                
 Asn Gly Val Pro Ser Arg Val Ser Ile Gln His Pro Leu Glu His
  65                  70                  75                



      <210> 1406
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 1406
 Met Ser Val Leu Glu Glu Asn Arg Pro Phe Ala Gln Gln Leu Ser Asn
   1               5                  10                  15    
 Val Tyr Phe Thr Ile Leu Ser Leu Phe Cys Phe Lys Leu Phe Val Lys
              20                  25                  30        
 Ile Ser Leu Ala Ile Leu Ser His Phe Tyr Ile Val Lys Gly Asn Arg
          35                  40                  45            
 Lys Glu Ala Ala Arg Ile Ala Ala Glu Phe Tyr Gly Val Thr Gln Gly
      50                  55                  60                
 Gln Glu Gln Leu Tyr Phe His Lys Ser Ser
  65                  70                



      <210> 1407
      <211> 305
      <212> PRT
      <213> Homo sapiens


      <400> 1407
 Met Ser Arg Asp His Arg Leu Leu Cys Leu Leu Gly Leu Cys Cys Val
   1               5                  10                  15    
 Ala Asp Ala Ser Lys Gln Pro Phe Arg Lys Ser Gly Ile Pro Arg Gly
              20                  25                  30        
 Tyr Thr Leu His Leu Arg Pro Ser Gly Tyr Asn Pro Asn Ser Gly Cys
          35                  40                  45            
 Gly Trp Arg Gln Ser Tyr Tyr Thr Met Leu Pro Ser Lys Leu His Phe
      50                  55                  60                
 Ile Trp Asn Arg Cys Gly Trp Gln Ala Glu Pro Leu Asn Thr Ala Ile
  65                  70                  75                  80
 Gln Val Asn His Ala Asp Leu Leu Glu His Ala Gly Pro Arg Gly Gly
                  85                  90                  95    
 Pro His Tyr Arg Phe Pro His Ser Gly Asp Gly Glu Asn Leu Ile Cys
             100                 105                 110        
 Leu Arg Ser Thr Ala Ser Val Cys Lys Gly Pro Ile Gln Val Gln Ile
         115                 120                 125            
 Gly Val Leu Thr Arg Thr Val Phe Gly Ala Ala Pro Leu Gln Thr Glu
     130                 135                 140                
 Pro His Gly Gln Ala Leu Met Gly Gly Gln Arg Thr Gln Asp Lys Ser
 145                 150                 155                 160
 Gln Thr Arg Glu Met Thr Glu Phe Leu Asn Ala Leu Gln Lys Leu Asn
                 165                 170                 175    
 Gln Asp Leu Leu Glu His Ser Trp Glu Glu Gly Asn Lys Gln Ile Pro
             180                 185                 190        
 Glu Gly Asp Asn Gly Gly Ser Arg Ser Leu Gln Pro Arg Cys Tyr Ser
         195                 200                 205            
 Asp Met Lys Pro Phe Thr Gln Ile Phe Leu Tyr Asn Gly Val Ser Pro
     210                 215                 220                
 Gln Ser Gly His Gly Ser Thr Val Glu Asp Val Glu Phe Ala Ala Arg
 225                 230                 235                 240
 His Gly Val Lys Gln Pro His Ala Gln Gln Ser Cys Arg His Tyr Leu
                 245                 250                 255    
 Ala Ala Ala Thr Met Ile Val Asp Arg Thr Leu Leu Leu Ala Pro Val
             260                 265                 270        
 Leu Phe Ala Phe His His Asp Trp Lys Leu Pro Glu Ala Ser Pro Ala
         275                 280                 285            
 Ala Asp Ala Gly Val Met Leu Leu Val Gln Pro Ala Glu Pro Trp Ala
     290                 295                 300                
 Lys
 305



      <210> 1408
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 1408
 Met Ala Pro Ala Leu Leu Ser Gly Val Ser Val Leu Leu Arg Leu Tyr
   1               5                  10                  15    
 Val Ala Pro Pro Gln Ala Gly Pro Thr Ala Trp Leu Ala Leu Pro His
              20                  25                  30        
 Ser Glu Leu Pro Glu Ser Val Pro Arg Asp Pro Ser Arg Cys Tyr Glu
          35                  40                  45            
 Ala Ser Tyr Asp Pro Ala Ser Glu Ile Pro Ala Cys His Phe Tyr Arg
      50                  55                  60                
 Thr Leu Ser Val Pro Arg Gly Glu Gln Thr Pro Val Cys Val Ala Val
  65                  70                  75                  80
 Asn Ser Val Leu Cys Pro Phe Thr Leu Thr Lys Gly Leu Cys Lys Gln
                  85                  90                  95    
 Leu Asp Met Gly Ile Ala Ala Arg Arg Arg Leu Ala Ser
             100                 105                



      <210> 1409
      <211> 81
      <212> PRT
      <213> Homo sapiens


      <400> 1409
 Met Ala Leu Lys Ile Met Leu Gln Ala Ile Phe Val Gly Leu Asn Gly
   1               5                  10                  15    
 Ile Glu Thr Gly Arg Thr Pro Ala Ser Pro Gln Ser Gly Thr Ser Arg
              20                  25                  30        
 Glu Met Trp Ala Gln Glu Pro Val Thr Gln Glu Glu Arg Val Gly Lys
          35                  40                  45            
 Leu Thr Ser Phe Leu Trp Ala Glu Gly Gly Gly Gly Cys Ser Lys Gly
      50                  55                  60                
 Ala Leu Leu Gly Arg Ser Ala Leu Val Leu Ala Ala Ala Val Ala Ala
  65                  70                  75                  80
 Glu
    



      <210> 1410
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1410
 Met Ala Ser Arg Gly Val Val Gly Ile Phe Phe Leu Ser Ala Val Pro
   1               5                  10                  15    
 Leu Val Cys Leu Glu Leu Arg Arg Gly Ile Pro Asp Ile Gly Met Leu
              20                  25                  30        
 His Arg Thr Thr Ala Ser Ser Ala Ala Trp Leu Arg Ser Ser Phe Asp
          35                  40                  45            
 Tyr Asn Ser Gln Thr Ala Ser Pro Leu Pro Pro His Phe Arg Ser
      50                  55                  60            



      <210> 1411
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1411
 Met Ala Tyr Cys Ser Thr Cys Leu Phe Phe Tyr Val Phe Gln Val Lys
   1               5                  10                  15    
 Asn Arg Phe Tyr Arg Leu Phe Glu Phe Arg Lys Met Ile Gly Asn Arg
              20                  25                  30        
 Glu Arg Cys Gln Asn Leu Val Ser Ser Asp Tyr Pro Val His Ile Asp
          35                  40                  45            
 Lys Ile Glu Glu Gln Ser Asp Cys Lys Ile Leu Asp Gly His Phe Val
      50                  55                  60                
 Ser Pro Met Ala His Tyr Val Pro Asp Ile Met Pro Ile Glu Ser Val
  65                  70                  75                  80
 Ile Ala Ser Asn Asp Lys Ile Val Ile His Val Trp Ala Phe Glu Lys
                  85                  90                  95    
 Phe Phe Ser Gln Glu Glu Ile Ile Leu
             100                 105



      <210> 1412
      <211> 478
      <212> PRT
      <213> Homo sapiens


      <400> 1412
 Met Ala Leu Leu Ala Ser Val Ala Leu Pro Trp Leu Phe Trp Leu Pro
   1               5                  10                  15    
 Leu Gln Pro Ser Phe Met Leu Leu Asp Ser Thr Ala His Ala Ala Pro
              20                  25                  30        
 Gln Arg Lys Trp Leu Leu Leu Leu Ala Ser Ser Gly Leu Gly Asp Val
          35                  40                  45            
 Gly Asp Asp Asp Ser His Gly Lys His Gly Lys His Asn Arg Gly Thr
      50                  55                  60                
 Leu Tyr Cys Val Tyr Pro Asn Leu Thr Asn Leu Glu Phe Cys Gly Val
  65                  70                  75                  80
 Val Ser Gln Glu Pro Pro Cys Ser Ala Gln Leu Leu Ala Ala Val Leu
                  85                  90                  95    
 Gly Trp Glu Val Gln Leu Ser Ala Ser Glu Ser Glu Gly Ser Arg Asn
             100                 105                 110        
 Glu Glu Asn Leu Gln Glu Leu Pro Arg Thr Val Thr Cys Leu Ile Pro
         115                 120                 125            
 Cys Ser His Pro Cys Ser Met Asn Lys Ile Ile Ala Gln Cys Pro Ile
     130                 135                 140                
 Arg Gly Gln Asn Tyr Pro Leu Val Gly Asn Cys Cys Thr Ser Gly Arg
 145                 150                 155                 160
 Trp Ser Asn Ile Ser Pro Glu Lys Glu Ala Arg Ala Arg Ser Tyr Glu
                 165                 170                 175    
 Pro Leu Lys Asp Leu Lys Gln Gly Arg Val Val Ser Gly Ala Tyr Lys
             180                 185                 190        
 Asn Arg Asn Thr Glu Lys Pro Gly Cys Met Gly Arg Lys Pro Met Ser
         195                 200                 205            
 Asp Pro Gln Leu Pro Lys Arg His Asn Gln Ile Trp Phe Trp Lys Glu
     210                 215                 220                
 His Ser Ile Gly His Met Lys Gly Pro Glu Glu Ala Gly Asp Tyr Lys
 225                 230                 235                 240
 Thr Val Ala Gln Val Leu Gln Pro Met Leu Arg His Leu Arg Gly Leu
                 245                 250                 255    
 Ala Val Asn His Asp Asn Phe Phe Glu Ile Trp Leu Gln Leu Leu Thr
             260                 265                 270        
 Ile Cys Arg Val Leu Thr Glu Val Gly Gly Glu Ser Val Asp Glu Trp
         275                 280                 285            
 Gln Ala Ala Glu Arg Pro Val Lys Glu Ser Trp Gly His Phe Asn Met
     290                 295                 300                
 Ala Leu Phe Ser Gly His Thr Gly Ala Val Gly Ala Ser Lys Pro Trp
 305                 310                 315                 320
 Ala Gln Ala Ser His Gly Tyr Lys Pro Glu Asp Glu Pro Gln Val Gln
                 325                 330                 335    
 Ala Val Thr Tyr Ser Ile Ser Arg Asp Phe Glu Gln Ser Ser Gln Ser
             340                 345                 350        
 Ser Thr Met Ala Glu Leu Ile Tyr Thr Pro Thr Glu Ser Val Ala Ile
         355                 360                 365            
 Thr Ile Thr Ala Pro Pro Gly Gly Pro Leu Lys Leu Ala Leu Cys Glu
     370                 375                 380                
 Gly Glu Ser Trp Thr Ser Gln His Ile Phe Leu Ser His Ile Tyr Ser
 385                 390                 395                 400
 Gln Ala Ile Phe Val Ser Lys Arg Phe His Thr Leu Asp Val Lys Leu
                 405                 410                 415    
 Ser Phe Arg Arg Lys Phe Gly Asp Arg Asp Thr Gln Gly Glu Arg His
             420                 425                 430        
 Val Glu Val Lys Ile Lys Asn Thr Thr Val Leu Leu Gln Ala Lys Glu
         435                 440                 445            
 Cys Gln Gly Pro Pro Ala Asn His Gln Glu Ala Gln Gly Glu Ala Gln
     450                 455                 460                
 Asn Glu Phe Phe Leu Thr Asp Leu Arg Arg Asn Gln Arg Cys
 465                 470                 475            



      <210> 1413
      <211> 116
      <212> PRT
      <213> Homo sapiens


      <400> 1413
 Met Thr Ala Glu Phe Leu Ser Leu Leu Cys Leu Gly Ser Leu Pro Glu
   1               5                  10                  15    
 Pro Leu Leu Ser Val Asn Val Asp Pro Gly Met Thr Pro Gly Leu Arg
              20                  25                  30        
 Thr Leu Arg Cys Leu Thr Pro Tyr Asn Gly Thr Glu Cys Ile Val Ile
          35                  40                  45            
 Ala Leu Leu Lys Met Gly Ile Pro Glu Pro Leu Gln Val Arg Gln Val
      50                  55                  60                
 Arg Lys Asn Gln Thr Asp Phe Met Leu Trp Asn Val Thr Ser Asn Asp
  65                  70                  75                  80
 Ser Gly Asn Tyr Ser Cys Val Tyr Tyr Leu Ser Asn Ser Ser His Leu
                  85                  90                  95    
 Ala Ser Phe Pro Ser Asn Lys Leu Glu Ile Trp Val Thr Ala Ala Lys
             100                 105                 110        
 Lys Arg Ser Ser
         115    



      <210> 1414
      <211> 302
      <212> PRT
      <213> Homo sapiens


      <400> 1414
 Met Ala Thr Leu Leu Leu Ala Val Val Thr Pro His Leu His Ser His
   1               5                  10                  15    
 Asn Met Gly Thr Cys Gly Tyr Tyr Thr His Thr Ala Thr Leu Trp Ser
              20                  25                  30        
 Ser Val Ser Ser Pro Gly Ala Leu Val Leu Thr Arg Gly His Arg Leu
          35                  40                  45            
 Leu Ser Asn Ser Val Thr Ser Thr Val Leu Ile Asn Ile Cys Ile Ser
      50                  55                  60                
 Gly Cys Met Leu Leu His Val Gly Thr Thr Ala His Val Ala Val Glu
  65                  70                  75                  80
 His Leu Ile Gly Gly Val Gln Asp Asp Glu Asp Leu Glu Met Thr Ile
                  85                  90                  95    
 Gly Cys His Gly Glu Glu Met Ile Gly Asp Leu Asp Lys Asn Ser Phe
             100                 105                 110        
 Gly Ala Gly Gly Leu Cys Ile Gly Glu Arg Val Gly Gly Pro Gly Cys
         115                 120                 125            
 Cys Glu Val Leu Ile Arg Met Thr Pro Thr Glu Asp Val Gly Glu Glu
     130                 135                 140                
 Arg Ser Asp Met Lys Gly Ile Gln Leu Ser Met Gln Glu Arg Thr Arg
 145                 150                 155                 160
 Cys Arg Gln Phe Pro Glu Gly Arg Arg His Gln Leu Gly His Leu Leu
                 165                 170                 175    
 Gln Gly Gly Leu Gly Arg Gly Glu Ala Trp Lys Tyr His Gln Ile Trp
             180                 185                 190        
 Glu Glu Gly His Trp Leu Leu Arg Glu Gln Pro Arg Gly Val Glu Ala
         195                 200                 205            
 Leu Phe Trp Arg Gly Asp Thr Glu Asp Pro Ser Leu Phe Pro Tyr Thr
     210                 215                 220                
 Ala Pro Ile Gln Lys Val Glu Phe Leu Phe Gln Pro Ser Ile Lys His
 225                 230                 235                 240
 Thr Glu Asn Phe Pro Leu Ile His Asp Phe Tyr Thr Gly Lys Ser Glu
                 245                 250                 255    
 Ile Lys Val Ala Asn Gln Leu Ser His His Leu Gly Phe Pro Asp Arg
             260                 265                 270        
 Arg Pro Val Pro Thr Ser Ile Tyr Arg Lys His Trp Glu Tyr Leu Lys
         275                 280                 285            
 Gly Glu Leu Ser Leu Lys Thr Ala Arg Asp Lys Gly Val Lys
     290                 295                 300        



      <210> 1415
      <211> 312
      <212> PRT
      <213> Homo sapiens


      <400> 1415
 Met Gly Cys Thr Leu Gln Ser Gly Cys Leu Leu Leu Leu Arg Arg Gly
   1               5                  10                  15    
 Gln Ala Gln Met Arg Lys Phe His Thr Tyr Asp Leu Asp Leu Thr Ile
              20                  25                  30        
 Ser His Cys Leu His Arg Glu Ala Ser Ile Arg Ser Asn Trp Gln Ala
          35                  40                  45            
 Gly Thr His Ser Ser Asp Thr Val Ile Ser Leu Leu Gln Phe Pro Met
      50                  55                  60                
 Ile Arg Gly Glu Lys Ser Phe Gly Ile Phe Val Pro Glu Ser His Gln
  65                  70                  75                  80
 Asn Arg Tyr Phe Ser Tyr Val Lys Arg Leu Leu Leu Leu Thr Gln Ser
                  85                  90                  95    
 Met Val Thr Met Leu Met Lys Pro Gly Glu Leu Arg Arg Phe Ser His
             100                 105                 110        
 Gly Pro Ser Gln Val Lys Ala Val Leu Glu Asn Ser Phe Arg Ala Trp
         115                 120                 125            
 Gly Gly Ser Val Val Leu Asp Trp Leu Glu Ser His Ala Glu Gln Gln
     130                 135                 140                
 Glu Asp Arg Ser Leu Leu Glu Glu Thr Ala Pro Pro Gly Cys Thr Leu
 145                 150                 155                 160
 Gln Gly Gly His Arg Ala Tyr His Pro Glu Ala Ala Asp Gly Thr Ala
                 165                 170                 175    
 Leu Phe Glu Leu Tyr Cys Pro Gly Glu Arg Ser Leu His Leu Asp Leu
             180                 185                 190        
 Gln Glu Phe Tyr Arg Leu Val Trp Ser Gly His Ser Arg Thr Val Leu
         195                 200                 205            
 Gly Trp Ala Asp Cys Glu Tyr Gly Val Leu Ser Gly Gly Ala Pro Ala
     210                 215                 220                
 Gly Ala Gly Gln Ile Leu Gly Ala Leu Thr Lys Gly His Ala Leu Gln
 225                 230                 235                 240
 Met Arg Phe Asp Gln Arg Phe Ser Arg Ile Pro Glu Glu Leu Cys Thr
                 245                 250                 255    
 Ser Lys Pro Val Arg Pro Gln Gln Asn Lys Tyr Leu Ser Ser Val Pro
             260                 265                 270        
 Leu Ser Ala Asn Gln Ala Val Ser Gln Ser Tyr Trp Leu Ser Phe Lys
         275                 280                 285            
 Ile Tyr Arg Glu Ser Asn Leu Thr Ile Phe Ala Val Pro Met Val Pro
     290                 295                 300                
 Ala Thr Ile Thr Pro Pro Pro Asp
 305                 310        



      <210> 1416
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 1416
 Met Thr Pro Phe Leu Gly Val Ile Ser Gln Leu Leu Gly Gly Arg Leu
   1               5                  10                  15    
 Leu Ile Ser Asp Leu Phe His His Gly Lys Gly Ser Gly Leu Ser Ser
              20                  25                  30        
 Pro Glu Gln Thr Leu Thr Leu Asp Met Gly Leu Leu Ile Leu His Ala
          35                  40                  45            
 Met Leu Leu Pro Arg Leu Pro Ser Val Asp Ser Arg Asn Ala Leu Pro
      50                  55                  60                
 Thr Ile Met Val Phe His Thr Ala Leu Leu Leu Thr Lys Ala Leu Thr
  65                  70                  75                  80
 Leu Gln Leu Arg Thr Arg Ile His Gly Ser Arg Asn Gln Gly Val Glu
                  85                  90                  95    
 Met Glu Val Ala Pro Leu Pro Ile Thr Pro Ser Asp Arg Leu Ala Lys
             100                 105                 110        
 Phe Leu Pro Pro Val Pro Ala Thr Leu Cys Ser Ala Gly Leu Lys Val
         115                 120                 125            
 Leu Val Pro Glu Gly Gly Met Leu Ser Leu Gly Asp Thr Thr Met Ile
     130                 135                 140                
 Pro Leu Asn Leu Lys Leu Arg Trp Pro Pro Ser His Phe Gly Leu Pro
 145                 150                 155                 160
 Leu Ser Gln Gln Ser Lys Lys Gly Val Ile Val Leu Ala Gly Val Thr
                 165                 170                 175    
 Asp Pro Asp Tyr Gln Asp Glu Ile Ser Leu Leu Leu His Asn Gly Gly
             180                 185                 190        
 Met Glu Glu Tyr Ala Trp Asn Thr Gly Asp Pro Leu Gly Arg Leu Leu
         195                 200                 205            
 Val Leu Ala Cys Pro Val Ile Lys Val Asn Gly Lys Leu Gln Gln Pro
     210                 215                 220                
 Asn Pro Gly Arg Thr Thr Asn Ala Pro Asn Pro Leu Gly Met Lys Ile
 225                 230                 235                 240
 Trp Val Thr Pro Pro Gly Lys
                 245        



      <210> 1417
      <211> 251
      <212> PRT
      <213> Homo sapiens


      <400> 1417
 Met Glu Ser Leu Gly Gly Trp Val Pro Met Val Met Phe Cys Cys Ser
   1               5                  10                  15    
 Arg Thr Arg Cys Glu Thr Phe Trp Ala Val Cys Gly Phe Glu Leu Cys
              20                  25                  30        
 Leu Cys Leu Phe Ala Ser Arg Phe Leu Leu Pro Val Gln Met Ser Val
          35                  40                  45            
 Trp Val Gln Gly Ser Pro Gly Ala Ser Ile Pro Glu Phe Val Val Val
      50                  55                  60                
 Cys Glu Asp Ile Phe Ser Gly Thr Gly Val Val Leu Gln Pro Val Thr
  65                  70                  75                  80
 Thr Val Glu Phe Val Cys Lys Ile Lys Met Gln Gly Phe Pro Met Leu
                  85                  90                  95    
 Trp Glu Thr Gln Ser Ser Pro Gly Gly Arg Val Ser Gly Trp Phe Ser
             100                 105                 110        
 Leu Thr Ser Gln Cys Ala Val Gly His Pro Leu Pro Leu Pro Leu Ser
         115                 120                 125            
 Val Gly Ser Arg Pro Glu Gln Pro Lys Ala His Gln Trp Ser Gln Leu
     130                 135                 140                
 Pro Gln Trp Glu Leu Lys Cys Pro Leu Ser Pro Cys Gly His Leu Ile
 145                 150                 155                 160
 Cys Trp Ile Leu Ser Gln Asn Gly Gly Arg Ala Met Gly Lys Gly Gln
                 165                 170                 175    
 Val His Trp Pro Leu Ser Pro Gly Glu Gln Pro Glu Val Arg Ala Val
             180                 185                 190        
 Pro Gly Asn Lys Lys Asp Ser Lys Asp Leu Glu Gln Ile Trp Ser Thr
         195                 200                 205            
 Val Ser Trp Arg Ser Arg Ala Arg Ile Ala Ala Cys Lys Gly Glu Gly
     210                 215                 220                
 Ala Glu Lys Ala Arg Trp Thr Glu Arg Asp Arg Cys Gly Pro Phe Arg
 225                 230                 235                 240
 Asp Pro Asp Gln Cys Leu Met Ala Ser Asp Val
                 245                 250    



      <210> 1418
      <211> 132
      <212> PRT
      <213> Homo sapiens


      <400> 1418
 Met Val Leu Phe Glu Thr Thr Ile Ile Ser Ala Val Thr Phe Cys Ser
   1               5                  10                  15    
 Val Leu Leu Ser Ala Tyr Leu Glu Leu Glu Asn Pro His Leu Pro Phe
              20                  25                  30        
 Glu Val His Val Ser Phe Ser Pro Leu Ala Leu Val Tyr Arg Val Trp
          35                  40                  45            
 Asn Asp Leu Ser Leu Asn Val Ile Gly Thr Lys Ser Ser His Trp Ala
      50                  55                  60                
 Trp Thr Phe Phe Trp His Thr Thr Pro Glu Glu Gly Trp Gly Glu Leu
  65                  70                  75                  80
 Ile Glu Ala Asp Thr Leu Thr Ala Glu Lys Val Thr Asp Asp Arg Glu
                  85                  90                  95    
 Glu Gly Asp Arg Lys Pro Lys Ser Gln Cys Arg Val Leu Gln Tyr Asn
             100                 105                 110        
 Val Ser Met Glu Pro His Asp Asp Ser Glu Leu Ser Glu Lys Asn Lys
         115                 120                 125            
 Leu Tyr Cys Phe
     130        



      <210> 1419
      <211> 97
      <212> PRT
      <213> Homo sapiens


      <400> 1419
 Met Lys Arg Phe Leu Phe Leu Leu Leu Thr Ile Ser Leu Leu Val Met
   1               5                  10                  15    
 Val Gln Arg Ser Leu Asp Val Gln Glu Cys Lys Glu Asp Arg Thr Leu
              20                  25                  30        
 Pro Phe Gln Lys Gln Leu Glu Ser Gln Lys Arg Leu Leu Phe Gln Glu
          35                  40                  45            
 Ala Ala Leu Val Ala Ser Gln Val Pro Arg Gly Glu Ser Val Gln Gln
      50                  55                  60                
 Thr Gly Ala Ile Lys Phe Leu Ile Lys Asn Ser Leu Ile Thr Ile Lys
  65                  70                  75                  80
 Thr Ser Leu Ile Ser Ile Lys Asn Ser Ser Ser Cys Ser Ser Ile Lys
                  85                  90                  95    
 His
    



      <210> 1420
      <211> 186
      <212> PRT
      <213> Homo sapiens


      <400> 1420
 Met Asp Cys Arg Val His Met Arg Pro Ile Gly Leu Thr Trp Val Leu
   1               5                  10                  15    
 Gln Leu Thr Leu Ala Trp Ile Leu Leu Glu Ala Cys Gly Gly Ser Arg
              20                  25                  30        
 Pro Leu Gln Ala Arg Ser Gln Gln His His Gly Leu Ala Ala Asp Leu
          35                  40                  45            
 Gly Lys Gly Lys Leu His Leu Ala Asp Ala Asn Pro Ser Trp Asn Thr
      50                  55                  60                
 Ser Asn Val Pro Phe Ala Val Ala Ser Ala Cys Gly Tyr Trp Gly Phe
  65                  70                  75                  80
 Ala Asn Cys Glu Asp Asp Ile Thr Cys Gly Pro Thr Trp Leu Pro Leu
                  85                  90                  95    
 Ser Glu Lys Arg Gly Cys Glu Pro Ser Cys Leu Thr Tyr Gly Gln Thr
             100                 105                 110        
 Phe Ala Asp Gly Thr Asp Leu Cys Arg Ser Ala Leu Gly His Ala Leu
         115                 120                 125            
 Pro Val Ala Ala Pro Gly Ala Arg His Cys Phe Asn Ile Ser Ile Ser
     130                 135                 140                
 Ala Val Pro Arg Pro Arg Pro Gly Arg Arg Gly Arg Glu Ala Pro Ser
 145                 150                 155                 160
 Arg Arg Ser Arg Ser Pro Arg Thr Ser Ile Leu Asp Ala Ala Gly Ser
                 165                 170                 175    
 Gly Ser Gly Ser Gly Ser Gly Ser Gly Pro
             180                 185    



      <210> 1421
      <211> 180
      <212> PRT
      <213> Homo sapiens


      <400> 1421
 Met Val Ala Ser Met Ile Ala Met Val Leu Glu Leu Val Val Val Leu
   1               5                  10                  15    
 Leu Ser Pro Asn Ile Ser His Phe Gly Arg Glu Ala Leu Gln Ile Ile
              20                  25                  30        
 Ser Ile Ile Gln Arg Pro Val Lys Ser Tyr Arg His Ile His Arg Ile
          35                  40                  45            
 Thr Ala Leu Lys Thr Leu Leu Lys Leu Met Lys Thr Ile Tyr Gly Gln
      50                  55                  60                
 Cys Ile Phe Lys Ser Ser Arg Ser Gly Glu Lys Thr Glu Thr Lys Lys
  65                  70                  75                  80
 Lys Phe Gln Tyr Asn Glu Leu Gly Cys Phe Asp Gln Arg Phe His Gly
                  85                  90                  95    
 Leu Asn Tyr Ser Thr Leu Val Lys Val Ser Ser Pro Lys Pro Leu Leu
             100                 105                 110        
 Lys Leu Thr Tyr Ile Val Pro Glu Leu His Ala Cys Ala Pro Arg Ala
         115                 120                 125            
 Asp Val Leu Pro Gln Glu Gln Val Ile Lys Ser His Cys Val Asp His
     130                 135                 140                
 Val Glu Glu Leu Phe Glu Tyr Leu Gln Asp Asp Leu Arg Val Gln Ala
 145                 150                 155                 160
 Leu Val Thr His Asp Cys Met Lys Gly Ile His Leu Ala Asp Asp Ser
                 165                 170                 175    
 Phe Gln Ala Val
             180



      <210> 1422
      <211> 343
      <212> PRT
      <213> Homo sapiens


      <400> 1422
 Met Leu Asp Ala Pro Cys Pro Gln Thr Leu Asp Ser Lys Phe Phe Gly
   1               5                  10                  15    
 Phe Trp Thr Leu Gly Phe Thr Pro Val Val Cys Gln Gly Leu Leu Ser
              20                  25                  30        
 Leu Trp Pro Gln Thr Lys Gly Cys Thr Val Ser Phe Pro Thr Phe Glu
          35                  40                  45            
 Val Leu Gly Leu Gly Leu Ala Ser Leu Leu Phe Ser Leu Gln Thr Ala
      50                  55                  60                
 Tyr Cys Gly Ala Ser Thr Ser Asp Cys Pro Leu Trp Glu Val Ala Ala
  65                  70                  75                  80
 Pro Ser Ser Ser Gln Arg Ala Ser Ser Gly Val Thr Glu Leu Thr Arg
                  85                  90                  95    
 Val Thr Pro Val Asp Leu Gln Ile Glu Val Arg Thr Gln Gln Gly Ser
             100                 105                 110        
 Leu Pro Gly Lys Asn Ser Leu Pro Ser Lys Val Ser Asn Arg Pro Trp
         115                 120                 125            
 Leu Gly Pro Lys Cys Glu Thr Ile Val Lys Ser Gly Gly Gln Ser His
     130                 135                 140                
 Leu Val Lys Tyr Ser Pro Gly Phe Leu Leu Glu Cys Glu Ala Thr Val
 145                 150                 155                 160
 Lys Ser Ala Gly Gln Ser His Leu Gly Lys Tyr Ser Pro Gly Phe Leu
                 165                 170                 175    
 Val Arg Gly Leu Lys Pro Gly Cys Val Lys Glu Ser Cys Leu Ile Ser
             180                 185                 190        
 Ser Glu Val Gln Leu Ser Gln Phe Thr Pro Asn Lys Leu His Asp Phe
         195                 200                 205            
 Ile Thr Asp Arg Gly Gln Lys Leu Lys Glu Gly Gly Pro Asn Ala Pro
     210                 215                 220                
 Gly Thr Leu Val Lys Cys Arg Lys Ser Ser Arg Ala Arg Arg Ser Arg
 225                 230                 235                 240
 Ser Trp Glu Thr Arg Pro Ser Leu Arg Asn Gly Asp Asp Val Asn Arg
                 245                 250                 255    
 Val Ser Ile Glu Trp Leu Gly Asp Arg Val Gly Ile Ser Gln Glu Glu
             260                 265                 270        
 Val Ala Ala Gln Gly Leu Ala Gly Ser Pro Ala Gln Thr Ser Pro Gly
         275                 280                 285            
 Gln Arg Arg Ser Ala Ala Gln Ala Leu Thr Ala Arg Leu Gln Gly Cys
     290                 295                 300                
 Gly Trp Arg Val Pro Ala Cys Pro Ala Leu Ala Leu Gly Glu Gly Arg
 305                 310                 315                 320
 Thr Pro Arg Asp Gly Arg Gly Arg Thr Ser Ala Ser Gly Ser Leu Glu
                 325                 330                 335    
 Ser Pro Pro Cys Asn Ser Thr
             340            



      <210> 1423
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1423
 Met His Gly Gly Ile Ser Arg Ala Glu Cys His Leu Val Thr Val Leu
   1               5                  10                  15    
 Leu Leu Pro Leu Thr Lys Thr Ala His Thr His Arg Gln Asn Lys Lys
              20                  25                  30        
 Gly Gly Ala Ala Leu Lys Cys Cys Pro Phe Asn Pro His Cys Asn Cys
          35                  40                  45            
 Asn Cys Met Ala Lys Leu Cys Leu Pro Arg Asn Asp Thr Ser Asp Arg
      50                  55                  60                
 Gly Glu Lys Thr Thr His Ala Ala Asp Glu Val Leu Ile Thr Lys Phe
  65                  70                  75                  80
 Pro Asn Pro Trp Lys Ala Ala Val Lys Ser Lys Lys Leu Arg Ser Ser
                  85                  90                  95    
 Thr Asn Pro Asn Glu Lys Asn Ala Lys Ser Ser Thr Pro Thr His Ile
             100                 105                 110        
 Thr Ile Arg Leu Lys Pro Gln Thr Glu Thr Leu Lys Ser Ser Asp Arg
         115                 120                 125            
 Gly Ala Thr Cys His Glu Arg Gly Ser
     130                 135        



      <210> 1424
      <211> 216
      <212> PRT
      <213> Homo sapiens


      <400> 1424
 Met Glu Ala Asp Thr Pro Ser Pro Arg Lys Phe Tyr Asp Leu Trp Ile
   1               5                  10                  15    
 Ser Tyr Ala Ser Asn Val Ile Phe Ser Val Arg Ala Phe Leu Gly Thr
              20                  25                  30        
 Leu Phe Thr Ile Ala Arg Pro Ala Pro Thr Leu Phe Ser Thr Leu Leu
          35                  40                  45            
 Ser Pro Leu Ala Val Val Thr Pro Asn Val Leu Cys Ile Leu Phe Leu
      50                  55                  60                
 Tyr Ile Val His Trp Gly Ser Thr Tyr Glu Asp Pro Gly Pro Ala Glu
  65                  70                  75                  80
 Arg Val Asp Asn Glu Asp Ser Gln Ala Thr Val Thr His Gly Glu Ala
                  85                  90                  95    
 Leu Ser Ile Trp Pro Ala Cys Lys Arg Arg Asn Val Leu Ala Ser Gly
             100                 105                 110        
 Leu Gly Gly Ile Ser Phe Ser Ser Tyr Gln Val Thr Leu Ser Pro Gly
         115                 120                 125            
 Ile Val Glu Lys Phe Val Ala Thr Gly Met Pro Ser Asn Gly Gly Ser
     130                 135                 140                
 Leu Tyr Thr Cys Ala Leu Lys Asn Leu Lys Gln Asn Lys Ser Phe Gly
 145                 150                 155                 160
 Lys Tyr Met Trp Val Pro Glu Thr Ser Gln Lys Thr Ser Ala Phe Asn
                 165                 170                 175    
 Pro Leu Val Leu Gly Thr Asn Glu Lys Leu Ile Trp Pro Arg Asp Pro
             180                 185                 190        
 Gly Arg Thr Leu Gly Ala Leu Phe Pro Trp Ala Ala Gly Leu Phe Leu
         195                 200                 205            
 Glu Thr Ser Leu Thr Gln Asp Thr
     210                 215    



      <210> 1425
      <211> 332
      <212> PRT
      <213> Homo sapiens


      <400> 1425
 Met Gly Leu Leu Met His Leu Thr Phe Arg Ile Pro Trp Pro Ser Pro
   1               5                  10                  15    
 Val Tyr Leu Asn Cys Val Arg Thr Leu Thr Leu Pro Asp Ser Trp Ala
              20                  25                  30        
 Lys Ser Ala Asn Thr Lys Asn Ile Pro Cys Asp Phe Leu Asn Thr Val
          35                  40                  45            
 Leu Lys Val Lys Glu Arg Thr Ala Ala Arg Ile Val Glu Val Gln Ser
      50                  55                  60                
 Arg Val Lys Leu Leu His His His Arg Val Arg Val Lys Leu Pro His
  65                  70                  75                  80
 His Ser Ile Lys Val Ala Ser Ser Arg Ala Thr Met Lys Leu Arg Thr
                  85                  90                  95    
 Val Cys Val Pro Phe Pro Phe Ile Pro Gln Val Pro Ala Ser Val Ser
             100                 105                 110        
 Ser Met Asp Ala Ala Ala Val Asn Gly Ala Leu Leu Phe Gly Glu His
         115                 120                 125            
 Arg Pro Arg Thr Val Pro Val Leu Ser Val Asn Lys Tyr Thr Arg Arg
     130                 135                 140                
 Pro Ser Ser Ser Gly Ile Val Leu Val Arg Thr Thr Val Pro Gly Met
 145                 150                 155                 160
 Phe Ser Ser Phe Ile Ile Ile His Pro Tyr Thr Ala Leu Pro Met Ser
                 165                 170                 175    
 Lys Phe Thr Arg Lys Leu Pro Asn Lys Thr His Cys Ser Ala Thr Lys
             180                 185                 190        
 Val Ser Glu Glu Asp Ser Val Glu Arg Ala Gln Gly Glu Glu Arg Ile
         195                 200                 205            
 Arg Ala Gly Phe Ser Gly Glu Ser Ser Gly Arg Glu Ala Tyr Pro Cys
     210                 215                 220                
 Arg Ile Gln Trp Arg Glu Leu Arg Asp Arg Ser Val Ser Val Gln Asp
 225                 230                 235                 240
 Ser Val Glu Thr Ala Gln Gly Glu Lys Arg Ile Arg Ala Gly Phe Ser
                 245                 250                 255    
 Gly Glu Ser Ser Gly Thr Gly Ala Tyr Pro Cys Arg Ile Gln Gly Arg
             260                 265                 270        
 Leu Arg Ser Ala Asp Val His Gln Ala His His Thr Tyr Met His Thr
         275                 280                 285            
 Val His Gln Ala Cys Thr Asp Thr Gln Leu Thr His Ala Val Pro Leu
     290                 295                 300                
 Glu Gln Arg Gln Arg Tyr Thr Leu Asn Met Glu Ala Cys Tyr Leu Ile
 305                 310                 315                 320
 Cys Ile His Cys Thr Arg Cys Lys Asp Lys Gln Met
                 325                 330        



      <210> 1426
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1426
 Met Gln Gln Lys Arg Lys Lys Pro Ser Gln Gly Leu Val Gly Leu Ser
   1               5                  10                  15    
 Gly Gly Leu Leu Leu Val Trp Leu Leu Leu Thr Ala Ala Ser Gly Tyr
              20                  25                  30        
 Gly Arg Leu Gly His Ala Glu Gln Asp Glu Met Val Pro His Leu Val
          35                  40                  45            
 Lys Leu Phe Asp Phe Pro Gly His Arg Val Ser Gln Ile Tyr Thr Gly
      50                  55                  60                
 Tyr Thr Cys Ser Phe Ala Ile Ser Glu Val Gly Gly Leu Phe Phe Gln
  65                  70                  75                  80
 Gly Ala Thr Asn Thr Ser Arg Glu Ser Thr Thr Tyr Pro Lys Ala Val
                  85                  90                  95    
 Gln Asp Leu Cys Gly Trp Ile Ile Gln Ser Leu Ala Cys Gly Lys Ser
             100                 105                 110        
 Ser Ile Ile Val Ala Thr Glu Arg Ala Pro
         115                 120        



      <210> 1427
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 1427
 Met Asn Arg Leu Arg Pro Arg Ala Leu Arg Cys Ile Tyr Leu Cys Ala
   1               5                  10                  15    
 Trp Gln Leu Ala Arg Gly Asp Arg Gln Ser Trp Arg Leu Ala Ile Leu
              20                  25                  30        
 Glu Gly Gly Arg Arg Pro Met Cys Pro Leu Gly Leu Trp Pro Arg Arg
          35                  40                  45            
 Ala Asp Gly Asp Val Glu Val Ala Asp Arg Ala Phe Ser Glu Leu Leu
      50                  55                  60                
 Ala Lys Arg Pro Val Ser Pro Tyr Ser Gly Tyr Asn Gly Gln Leu Leu
  65                  70                  75                  80
 Thr Ser Val Tyr Gln Pro Thr Glu Met Ala Leu Met His Lys Val Pro
                  85                  90                  95    
 Ser Ser Glu Gly Met Glu Ser Asn Trp Arg Gln Arg Asp His Ala Val
             100                 105                 110        
 Tyr Val Val Ile Gln Met Arg Asn
         115                 120



      <210> 1428
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1428
 Met Ala Leu Arg His Leu Ala Leu Leu Ala Gly Leu Leu Val Gly Val
   1               5                  10                  15    
 Ala Ser Lys Ser Met Glu Asn Thr Asp Thr Asp Val Pro Ala Pro Glu
              20                  25                  30        
 Val Leu Thr Arg Ser Thr Ala Gly Val Arg Gly Ala Cys Ala Ser Gln
          35                  40                  45            
 Arg Gly Ala Leu Arg Cys Leu Leu Gly Glu Arg Leu Leu Arg Asn Gly
      50                  55                  60                
 Trp Val Arg Arg Gly Pro His Gly Pro Gln Gly Thr Glu Gly His Pro
  65                  70                  75                  80
 Met Leu Thr Pro Glu Glu Ala Gly Ala Ala Asp Ile Glu Met Cys Ser
                  85                  90                  95    
 His Gly Thr Pro Gln Pro Leu Leu Leu Trp Ala
             100                 105        



      <210> 1429
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1429
 Met Met Pro Thr Pro Leu Leu Met Leu Leu Pro Val Ala Thr Thr Gly
   1               5                  10                  15    
 His Arg Cys Arg Leu Leu Leu Cys Ala Gln Cys Asp Glu Ile Glu Met
              20                  25                  30        
 Ala Asn Glu His Thr Leu Ile His Pro Ala Ser Ile Glu Asp Pro Leu
          35                  40                  45            
 Glu Ala Arg Pro Met Ser Asp Glu Asp Pro Glu Asp Glu Asp Ala Leu
      50                  55                  60                
 Pro Ala Arg Ser Tyr Lys Thr Asn Arg Lys Gly Arg Ile Cys Asn Arg
  65                  70                  75                  80
 Asp His Lys Trp Ser Ala Lys Pro Lys Val Tyr Arg Asn Gly Gln Thr
                  85                  90                  95    
 Cys Ser Lys Gly Pro Ala Cys
             100            



      <210> 1430
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 1430
 Met Ala Ser Leu Ser Thr Ser Leu Ser Ile Arg Ile Leu Arg Ile Pro
   1               5                  10                  15    
 Phe Leu Pro Leu Leu Pro Ser Leu Leu Ser Gln Lys Pro Val Tyr Thr
              20                  25                  30        
 Ala Cys Leu Leu Arg Ser Lys Ala Lys Pro Trp Gly Trp Gly Gln Gln
          35                  40                  45            
 Ala Phe Asn Arg Ala Asp Pro Ser Leu Ser Ile Pro Asn Leu Val Val
      50                  55                  60                
 Arg Arg Gly Ser Val Glu Gly Ser Arg Ala Ser Trp Gly Gly Ala Phe
  65                  70                  75                  80
 Ile Met Cys Ser Lys Leu Gly Arg Ser Ile Leu Leu Glu Glu Ala Met
                  85                  90                  95    
 Ala Arg Glu Asp Ala Lys Pro His Val Gly Val Asp Gly Leu Tyr Leu
             100                 105                 110        
 Ala Tyr Gln Leu His Gly Phe Phe Lys Val Arg Leu Leu Val Arg Val
         115                 120                 125            
 Gly Phe Arg Val Gln Leu Ser Phe Lys Leu Glu Gly Trp Val
     130                 135                 140        



      <210> 1431
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 1431
 Met Gln Phe Met Ser Tyr Lys Ser Ser Gln Ile His Trp Leu Ser Thr
   1               5                  10                  15    
 Leu Asp Ala Leu Thr Phe Leu Val Ser Ala Phe Pro Cys Cys Ser Met
              20                  25                  30        
 Val Thr Asp Arg Glu Leu Ile Lys Arg Lys Thr Lys Gly Thr Leu Asn
          35                  40                  45            
 Ser Glu Tyr Val Cys Ala Asp Thr Gly Ile Tyr Arg Lys Glu Thr Tyr
      50                  55                  60                
 Gln Asn Met Asn Pro Asp Tyr Leu Trp Asp Lys Cys Leu
  65                  70                  75        



      <210> 1432
      <211> 64
      <212> PRT
      <213> Homo sapiens


      <400> 1432
 Met Lys Ser Met Leu Lys Leu Phe Leu Val Gly Leu Ile Asp Leu Pro
   1               5                  10                  15    
 Leu Lys Val Leu Gln Gln Arg Ser Thr Phe Phe Met Val Ser Gly Ser
              20                  25                  30        
 Pro Ala Glu Ile His Ser His Ser Arg Ile Gly Asn Lys Ala Ile Arg
          35                  40                  45            
 Ser Glu Phe Pro Leu Leu Asn Glu Thr Leu Ala Ser Ser Glu His Glu
      50                  55                  60                





      <210> 1433
      <211> 159
      <212> PRT
      <213> Homo sapiens


      <400> 1433
 Met Ala Leu Ala Ser Ala Leu Leu Leu Ile Thr Phe Gln Phe Ile Ala
   1               5                  10                  15    
 Thr Phe Ser Thr Leu Val Pro Leu Val Asp Cys Ser Ser Val Leu Gln
              20                  25                  30        
 Glu Arg Asn Asp Leu Thr Glu Val Ala Leu Gln Lys Val Phe Asn Phe
          35                  40                  45            
 Ser Thr Ser His Ile Phe Glu Thr Arg Val Ala Gly Arg Met Val Ala
      50                  55                  60                
 Asp Met Cys Arg Ala Ala Val Lys Lys Val Thr Arg Arg Gln Arg Arg
  65                  70                  75                  80
 Cys Glu Glu Ala Gly Ile Val Gly Glu Gly Arg Thr Gly Gly Ser Lys
                  85                  90                  95    
 Glu Thr Ser Gln Gly Thr Pro Pro Lys Thr Asn Ser Leu Cys Pro Ala
             100                 105                 110        
 Ser Pro Met Arg Lys Ser Pro Arg Arg Thr Leu Glu Lys Gly Ser Pro
         115                 120                 125            
 Leu Ser Leu Gly Ala Gly Ala Leu Ala Thr Gln Gly Pro Pro Gly Gly
     130                 135                 140                
 Lys Thr Thr Thr Arg Thr Leu Arg Glu Lys Gln Met Arg Arg Thr
 145                 150                 155                



      <210> 1434
      <211> 320
      <212> PRT
      <213> Homo sapiens


      <400> 1434
 Met Lys Asn Ser Leu Leu Gln Leu Arg Leu Val Arg Leu Ile Gln Ala
   1               5                  10                  15    
 Asn Leu Ser Val Leu Arg Pro Gly Ser Ala Met Ser Pro Arg Pro Pro
              20                  25                  30        
 His Gln Pro Val Ser Leu Glu Pro Ala Ala Glu Leu Met Trp Gln Ile
          35                  40                  45            
 Arg Ala Phe Gln Glu Phe Leu Arg Gln His Glu Glu Ala Thr Ser Thr
      50                  55                  60                
 Leu Ser Asn Leu Gln Trp Gly Pro Leu Glu Gly Gly Leu Phe Leu Gly
  65                  70                  75                  80
 Met Leu Val Thr Arg Ser Arg Ala Ser Leu Pro Asn Gly Pro Ala Ala
                  85                  90                  95    
 Gly Leu Thr Gly Pro Arg Ala Pro Leu Leu Ala Pro Val Val Gln Thr
             100                 105                 110        
 Thr Ile Ile Ile Lys Val Pro Trp Val Ile Met Glu Ile Glu Glu Arg
         115                 120                 125            
 Lys Val Asp Leu Leu Leu Asp Thr Gly Thr Gly Leu Ser Val Leu Leu
     130                 135                 140                
 Leu Asn Pro Gly Pro Leu Ser Ser Leu Ser Met Thr Cys Leu Leu Gln
 145                 150                 155                 160
 Gly Tyr Leu Gly Glu Asp Trp Gln Met Asp Phe Thr His Met Pro Lys
                 165                 170                 175    
 Glu Leu Lys Gln Leu Leu Lys Ala Gln Ser His Glu Pro Gly Pro Pro
             180                 185                 190        
 Leu Phe Asn Pro Gly Asp Leu Val Leu Val Lys Gly Phe Glu Gln Trp
         195                 200                 205            
 Gly Asn Gln Thr Ala Leu Ser Leu Gln Gly Ser Ile Pro Ala Val Gly
     210                 215                 220                
 Glu Lys Val Phe Phe Thr Asn Arg Gln Leu Val Tyr Leu Asp Ala Ile
 225                 230                 235                 240
 Ser Glu Ala Cys Ala Arg Ala Gly Ser Cys Ile Ala Val Pro Arg Ser
                 245                 250                 255    
 Pro Glu Glu Asn Glu Ala Ile Ala Arg Phe Leu Lys Lys Tyr Asn Met
             260                 265                 270        
 Tyr Ala Tyr Met Ala Leu Ala Lys Gly Pro Ser Pro Gly Asp Phe Cys
         275                 280                 285            
 Tyr Leu Asp Glu Ala Pro Val Asp Tyr Thr Asn Arg Cys Pro Gly Glu
     290                 295                 300                
 Leu Ile Gly Gln Gly Asn Glu Lys Cys Leu Glu Met Tyr Thr Val Glu
 305                 310                 315                 320





      <210> 1435
      <211> 113
      <212> PRT
      <213> Homo sapiens


      <400> 1435
 Met Gly Leu Leu Gly Gln Asp Leu Phe Val Thr Ser Phe Leu Cys Pro
   1               5                  10                  15    
 Thr Trp Pro Ser Pro Ser Gly Ala His Gly Leu Arg Glu Glu Pro Glu
              20                  25                  30        
 Phe Val Thr Ala Arg Ala Gly Glu Ser Val Val Leu Arg Cys Asp Val
          35                  40                  45            
 Ile His Pro Val Thr Gly Gln Pro Pro Pro Tyr Val Val Glu Trp Phe
      50                  55                  60                
 Lys Phe Gly Val Pro Ile Pro Ile Phe Ile Lys Phe Gly Tyr Tyr Pro
  65                  70                  75                  80
 Pro His Val Asp Pro Glu Tyr Ala Asp Val Ala Leu Met Pro Thr His
                  85                  90                  95    
 Ser Val Leu Ser Phe Trp Pro Ala Ala Tyr Leu Leu Gly His Trp Leu
             100                 105                 110        
 Trp
    



      <210> 1436
      <211> 422
      <212> PRT
      <213> Homo sapiens


      <400> 1436
 Met Cys Leu Arg Ala Arg Gly Gly Ala Leu Ala Leu Leu Thr Ala Thr
   1               5                  10                  15    
 Gly Leu Leu Leu Arg Arg Pro Glu Leu Thr Arg Pro Glu Cys Arg Leu
              20                  25                  30        
 Arg Ala Gly Ala Ala Ser Trp Trp Leu Met Ala Val Pro Phe Leu Phe
          35                  40                  45            
 Ala Ser Leu Gly Pro Glu Glu Glu Gly Val Ser Cys Val Ser Ser Leu
      50                  55                  60                
 Thr Cys Val His Ile Val Met Thr Val Lys Leu Ala Gly Pro Leu Phe
  65                  70                  75                  80
 Gly Leu Ser Trp Gly Cys Leu Asp Gly Gly Leu Gln Met Ser Arg Ala
                  85                  90                  95    
 Ser Gly Cys Ile Pro Asp Pro Gln Asp Pro Phe Val Val Gly Arg Asn
             100                 105                 110        
 Cys Leu Pro Leu Arg Pro Gly Asn His Pro Phe Pro Lys Arg Leu Pro
         115                 120                 125            
 Cys Ala Leu Trp Gly Thr Arg Arg Arg Arg Glu Gln Cys Glu Pro Phe
     130                 135                 140                
 Gly Tyr Thr Ser Pro Pro Arg Ala Gly Val Glu Trp Glu Thr Gly Ser
 145                 150                 155                 160
 His Cys Gly Cys Gly Gln Pro Asp Arg Arg Pro Gln Ile Asp Ser Gly
                 165                 170                 175    
 Ser Pro Phe His Ser Ser Lys His Ile Gly Gly Gly Ser Leu Gln Gln
             180                 185                 190        
 Pro Arg Ala Cys Thr Arg Tyr Tyr Ser Cys Gln Lys Thr Pro Ser Gly
         195                 200                 205            
 Leu Ser Arg Pro His Cys Cys Ala Glu Asp Val Val Asp Thr Arg Glu
     210                 215                 220                
 Gly Ser Glu Glu Ser Thr Gly Lys Gln Leu Gly Thr Leu Pro Leu Asn
 225                 230                 235                 240
 Gly Ala Gly Ser Gln Ala Leu Gly Leu Leu Cys Gly His Arg Gln Arg
                 245                 250                 255    
 Asn Ser Leu Asp Ser Gly Pro Ser Val Thr Ser Val Gln Ser Leu Phe
             260                 265                 270        
 Ser Arg Arg Leu Ser His Gln Ser Thr Arg Ile Ser Gln Ala Pro Ala
         275                 280                 285            
 Met Gly His Val Leu Ala Lys Gly Ala Val Gly Ala Gln Pro Leu Val
     290                 295                 300                
 Cys Ile Trp Gln Cys Gly Asp Thr His Glu Lys Phe Pro Ser Thr Ser
 305                 310                 315                 320
 Val His Asn Ser Lys Thr Leu Glu Met Met Gln Val Pro Val Asn Lys
                 325                 330                 335    
 Lys Gly Ser Gly Cys Pro Val Pro Gly Glu Arg Cys Ser Cys Tyr Gln
             340                 345                 350        
 Ser Ser Ala Val Ala Trp Phe Leu Ser Trp Gly Leu Thr Ser Leu Leu
         355                 360                 365            
 Gly Pro Gly Thr Trp Gly Ile Ala Ala Ala Cys Arg Leu Ala Ser Gly
     370                 375                 380                
 His Leu Gln Gly Arg Asn Leu Leu Asp Val Arg Val Ser His Ser Ile
 385                 390                 395                 400
 Arg Pro Gly Asp Pro Gly Gly Gln Gln Gln Ser His Thr Leu Phe Cys
                 405                 410                 415    
 Val Leu Ile Thr Lys His
             420        



      <210> 1437
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1437
 Met Pro Leu Val Met Pro Pro Leu Ala Ala Ala Pro Leu Leu Thr Trp
   1               5                  10                  15    
 Gln Arg His Thr Val Gly Thr Trp Asp Lys Ser Gly Thr Ser Glu Gly
              20                  25                  30        
 Ser Ala Ser Pro Pro Ser His Ala Thr Gly Trp Ile Thr Ala Pro Lys
          35                  40                  45            
 Gly Leu Gly Ser Arg Lys Ser Arg Leu Asn Pro Gly Phe Phe Leu Gln
      50                  55                  60                
 Lys Pro His His Cys Ser Cys Ala Asn Leu Val Val Gln Pro Ala Phe
  65                  70                  75                  80





      <210> 1438
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1438
 Met Ser Pro Val Ser Leu Cys Arg Leu Leu Cys Ala Leu Lys Ser Leu
   1               5                  10                  15    
 His Gly Thr Ser Gln Glu Thr Ser Ile Leu Gln Asp Asp Arg Lys Phe
              20                  25                  30        
 Cys Gln Leu Tyr Pro Leu Pro Lys Phe Pro Gln Ile Ala Gln Leu Ser
          35                  40                  45            
 Cys Asp Leu Val Ile Val Ile Pro Ser Lys Arg Arg Gly Cys Ile Phe
      50                  55                  60                
 Phe Lys Ser Ala Ala Ser Lys Ala Trp Ala Gly Gly Thr Leu Ala Gln
  65                  70                  75                  80
 Leu Pro Gly Glu Ser Val Ala Gln Ser Leu Val Leu Arg Gln Val Val
                  85                  90                  95    
 Thr Lys Thr Arg Asp Gln Pro Glu Arg Ala Gly Val Glu Ile Glu Pro
             100                 105                 110        
 Gln Glu Pro Pro Arg Leu Arg Leu Pro Thr Ile Cys Glu Thr Glu Phe
         115                 120                 125            
 Asn Ser Val Val Ile Thr Asn Ile Tyr Phe Asn Arg Met Thr Leu Asn
     130                 135                 140                
 Glu Ile Glu
 145        



      <210> 1439
      <211> 152
      <212> PRT
      <213> Homo sapiens


      <400> 1439
 Met Pro Arg Ala Thr Ser Ser Pro Ser Arg Val Leu Leu Gly Cys Ala
   1               5                  10                  15    
 Leu Leu Thr Ala Met Ala Ala Gly Gln Glu Gly Lys Ala Ala Ala Gly
              20                  25                  30        
 Asp Gly Thr Gln Ser Leu Ala Glu Leu Lys Val Lys Gly Gln Lys Arg
          35                  40                  45            
 Thr Arg Phe Pro Arg Glu Thr Glu Cys Arg Val Ser Lys Glu Leu Val
      50                  55                  60                
 Lys Leu Gly Leu Asp Gln Val Val Gly Ala Leu Arg Ser Ser Ala Thr
  65                  70                  75                  80
 Arg Leu Pro Ala Glu Ser Ser Glu Asn Lys Lys Pro Met Ala Lys Pro
                  85                  90                  95    
 Asp Asp Leu Leu Lys Phe Thr Ala Leu Asp Leu Asn Leu Ser Arg Ser
             100                 105                 110        
 Thr Lys Thr Arg Thr Pro Pro Cys Leu Ile Asn Asp Leu Glu Tyr Arg
         115                 120                 125            
 Ile Asp Gly Ser Ala Leu Ser Leu Arg Gln Gln Gln Arg Pro Phe Lys
     130                 135                 140                
 Thr Arg Leu Gln Ala Leu Lys Cys
 145                 150        



      <210> 1440
      <211> 295
      <212> PRT
      <213> Homo sapiens


      <400> 1440
 Met Arg Ile Arg Arg Trp Ser Leu Met Phe Asp Ser Val Trp Pro Met
   1               5                  10                  15    
 Cys Ala Phe Tyr Ser Trp Ala Lys Ala Ser Arg Thr Phe Leu Lys Ala
              20                  25                  30        
 Asp Gly Leu Pro Arg Arg Lys Gln Trp Val Leu Val Glu Ala Leu Ala
          35                  40                  45            
 Gly Gly Gly Val Leu Gly Val Lys Gln Ile Thr Ile Gln Val Leu Phe
      50                  55                  60                
 Glu Val Leu Leu Arg Arg Gly Lys Glu Ser Glu Thr Tyr Thr Lys Met
  65                  70                  75                  80
 Tyr Arg Arg Leu Gly Pro Glu Arg Cys Arg Arg Ser Lys Tyr Ala Gly
                  85                  90                  95    
 Val Glu Arg Ile Val Asp Lys Arg Lys Asn Lys Lys Gly Lys Trp Glu
             100                 105                 110        
 Tyr Leu Ile Arg Trp Lys Gly Tyr Gly Ser Thr Glu Asp Thr Trp Glu
         115                 120                 125            
 Pro Glu His His Leu Leu His Cys Glu Glu Phe Ile Asp Glu Phe Asn
     130                 135                 140                
 Gly Leu His Met Ser Lys Asp Lys Arg Ile Lys Ser Gly Lys Gln Ser
 145                 150                 155                 160
 Ser Thr Ser Lys Leu Leu Arg Asp Ser Arg Gly Pro Ser Val Glu Lys
                 165                 170                 175    
 Leu Ser His Arg Pro Ser Asp Pro Gly Lys Ser Lys Gly Thr Ser His
             180                 185                 190        
 Lys Arg Lys Arg Ile Asn Pro Pro Leu Ala Lys Pro Lys Lys Gly Tyr
         195                 200                 205            
 Ser Gly Lys Pro Ser Ser Gly Gly Asp Arg Ala Thr Lys Thr Val Ser
     210                 215                 220                
 Tyr Arg Thr Thr Pro Ser Gly Leu Gln Ile Met Pro Leu Lys Lys Ser
 225                 230                 235                 240
 Gln Asn Gly Met Glu Asn Gly Asp Ala Gly Ser Glu Lys Asp Glu Arg
                 245                 250                 255    
 His Phe Gly Asn Gly Ser His Gln Pro Gly Leu Asp Leu Asn Asp His
             260                 265                 270        
 Val Gly Glu Gln Asp Met Gly Glu Cys Asp Val Asn His Ala Thr Leu
         275                 280                 285            
 Ala Glu Asn Gly Leu Gly Leu
     290                 295



      <210> 1441
      <211> 258
      <212> PRT
      <213> Homo sapiens


      <400> 1441
 Met Pro Ser Leu Lys Ala Asn Phe Asp Leu Leu Ala Cys Leu Arg Gly
   1               5                  10                  15    
 Val Gly Ser Ser Thr Leu Leu Leu Trp Pro Ala Val Leu Gly Ala Gln
              20                  25                  30        
 Thr Arg Gln Ala Gly Val Asn Glu Gly Arg Ser Gln Val Ala Asp Phe
          35                  40                  45            
 Leu Arg Ile Pro Val Thr Gly Cys Pro Glu Gln Arg Arg Asn Pro Pro
      50                  55                  60                
 Ser Pro Pro Ala Pro Leu Gly Thr Gly Gly Pro Ala Glu Glu Arg Leu
  65                  70                  75                  80
 Gln Phe Pro Gly Val Ala Gly Ser Arg Arg Gly Arg Gly Arg Ile Leu
                  85                  90                  95    
 Arg Ala Gly Gly Ile Gly Arg Ala Ser Pro Gly Glu Gly Thr Gly Ala
             100                 105                 110        
 Pro Arg Pro Arg Ala Gly Gln Gly Arg Gly Gly Pro Gly Lys Pro Glu
         115                 120                 125            
 Ser Gly Gly Gly Gly Pro Val Ala Leu Arg Pro Gly Asp Cys Thr Cys
     130                 135                 140                
 Cys Val Leu Lys Ser Gln Pro Arg Gln Gln Arg Arg Gly Ala Cys Ser
 145                 150                 155                 160
 Ala Met Ala Phe Arg Val Arg Leu Arg Val Arg Gln Ser Val Arg Pro
                 165                 170                 175    
 Pro Arg Gly Val Ile Val Ala Ala Leu Gln Arg Pro Glu Thr Gln Gly
             180                 185                 190        
 Pro Ala Pro Ser Ser Ala Arg Pro Asp Cys Gly Pro Glu Ser Arg Gly
         195                 200                 205            
 Gly Leu Ala Leu Trp Arg Arg Leu Arg Gly Tyr Ala Ser Arg Asp Arg
     210                 215                 220                
 Val Leu Cys Asn Arg Arg Cys Pro His Ala Ala Arg Phe Pro Ser Lys
 225                 230                 235                 240
 Arg Thr Pro Ser Gly Ser Pro His Leu His Leu Met Ser Ser Trp Ala
                 245                 250                 255    
 Val Pro
        



      <210> 1442
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 1442
 Met Arg Glu Trp Glu Val Ala Val Pro Gln Thr Leu Ser Pro Ala Leu
   1               5                  10                  15    
 Ser Leu Ala Ala Arg Ala Ala Ser Leu Phe Leu Leu Ala Leu Trp Asp
              20                  25                  30        
 Gly Lys Val Leu Ala Cys Phe Phe Ala Pro Thr Lys Tyr Glu Leu Ala
          35                  40                  45            
 Thr Gln Ser Trp Pro Lys Lys Gly Tyr Gln Thr Leu Glu Ser Ala Leu
      50                  55                  60                
 Asp Cys Cys Arg Lys Leu Leu Ala Gly Leu His Leu Ala Gly Leu Leu
  65                  70                  75                  80
 Ser Val Gln Ala Val Asn Gln Ser Leu Leu Glu Ser Trp Gly Ala Pro
                  85                  90                  95    
 His Pro Ala Glu Pro Val Val Cys Ala Gly Ala Ala Trp Pro Arg Leu
             100                 105                 110        
 Met Gly Leu Lys Tyr Pro Val Ser Phe Gly Lys Ser Ala Glu Phe His
         115                 120                 125            
 Glu Gly Asp Val Gln Met Pro Leu Glu Lys Leu Trp Glu Gly Ala Glu
     130                 135                 140                
 His Cys Ser Arg Tyr Pro Glu Thr His Pro Asn His Pro Ser Gly Ala
 145                 150                 155                 160
 Thr Val Asn Val Val Ala Leu Phe Pro Gly Val Leu Arg Ile Gln Ala
                 165                 170                 175    
 Pro His Pro Thr His Tyr His Pro Thr His Pro Thr His Pro Pro Phe
             180                 185                 190        
 Leu Arg Pro Leu Pro Gln Ala Glu Asp Gly Asp Ile His Val Pro Asp
         195                 200                 205            
 Ser Thr Thr Glu Lys Gly His Leu Ala Pro Ser Leu Ala Ser Asn Met
     210                 215                 220                
 Cys Ser Pro Ser Asp Asp Ala Asn Ala Tyr Asp Asp Asn Asp Asp Glu
 225                 230                 235                 240
 Asn Asp Asp His Asp Asp Asn
                 245        



      <210> 1443
      <211> 356
      <212> PRT
      <213> Homo sapiens


      <400> 1443
 Met Glu Glu Ser Arg Gly Pro Leu Gly Ala Gly Asp Thr Gly Val Phe
   1               5                  10                  15    
 Thr Leu Arg Val Lys Leu Val Val His Val Trp Phe Val Asn Ala Leu
              20                  25                  30        
 Phe Ile Ser Leu Leu Asp Ser Asp Leu Lys Asp Ser Asn Thr His Ser
          35                  40                  45            
 Val Ser Pro Ser Ala Trp His Ile Leu Gly Thr Arg Leu Phe Pro Glu
      50                  55                  60                
 His Thr Ala Leu Glu Asn Val Ala Ala Pro Gly Gly Cys Arg Ala Leu
  65                  70                  75                  80
 Cys Trp Thr Gln Asn Ala Ser Cys Pro Leu Leu Pro Gly Thr Leu Thr
                  85                  90                  95    
 Pro Glu Pro Pro Ser His Ser Phe Pro Ala Pro Gly Ala Lys Ser Gly
             100                 105                 110        
 Ala Cys Val Trp Val Gly Glu Gly Gly Thr Val Asn Ser Glu Val Thr
         115                 120                 125            
 Trp Met Leu Glu Phe Thr Asp Ser Asn Ile Leu Ser Cys Cys Ser Thr
     130                 135                 140                
 Ser Ala Gly Ile Cys Ser Asp Phe Cys Gly Met Cys Pro Tyr Pro Gly
 145                 150                 155                 160
 Ile Ile Ser Ser Ser Gln Gly Ala Gly Trp Gln Glu Asn Val Gln Thr
                 165                 170                 175    
 Ser Tyr Leu Pro Ser Pro Asn Gly Asn Arg Lys Gly Leu Pro Arg Ser
             180                 185                 190        
 Ser Leu Ser Pro Ile Ile Ala Lys Trp Trp Ala Cys Asp Leu Lys Thr
         195                 200                 205            
 Gln Leu Glu Pro Pro Gly Ala Gly Ala Arg Gln Pro Pro Leu Pro Pro
     210                 215                 220                
 Asp Ser Pro Arg Tyr Cys Met Ile Ser Asp Leu Phe Ile Asp Asn Tyr
 225                 230                 235                 240
 Gln Val Lys Cys Ile Asn Gly Lys Met Cys Tyr Val Gln Lys Gln Pro
                 245                 250                 255    
 Ala Pro His Ser His Arg Met Ser Pro Glu Glu Val Ser Ala His Asp
             260                 265                 270        
 Ala Leu Ile Ser Lys Glu Ser Asn Thr Pro Lys Ile Asp His Cys Ser
         275                 280                 285            
 Ser Pro Ser Ser Ser Glu Asp Ser Gly Ile Asn Ala Ile Gly Ala His
     290                 295                 300                
 Tyr Val Glu Ser Cys Asp Glu Asp Thr Glu Glu Gly Ala Glu Leu Ser
 305                 310                 315                 320
 Ser Glu Glu Asp Tyr Ser Pro Glu Ser Ser Trp Glu Pro Asp Glu Cys
                 325                 330                 335    
 Thr Leu Leu Ser Pro Ser Gln Ser Asp Leu Glu Val Ile Glu Thr Ile
             340                 345                 350        
 Glu Thr Thr Val
         355    



      <210> 1444
      <211> 206
      <212> PRT
      <213> Homo sapiens


      <400> 1444
 Met Ala Ile Pro Val Leu Met Ala Val Glu Glu Leu Ile Gln Leu Val
   1               5                  10                  15    
 Gln Leu Leu Phe Leu Ala Val Asn His Ile His Thr Met Ala His Leu
              20                  25                  30        
 Ala Gln Arg Val Ser Ile Ser Ile Asn Arg Lys Ser Asn Leu Tyr Pro
          35                  40                  45            
 Ser Pro Asp Pro Gly Phe Gln Gly Leu Leu Gln Pro Met Gln Ile Gln
      50                  55                  60                
 Lys Trp Ser Ala Gln Ala Cys Gly Arg Ala Thr Val Ile Leu Gly His
  65                  70                  75                  80
 Met Thr Tyr Val Gly His Lys Lys Glu Ile Leu Gly Lys His Ser Gln
                  85                  90                  95    
 Glu Ala Leu Leu Asp Asn Val Gln Glu Ala Arg Ala Gln Leu Asp Thr
             100                 105                 110        
 Leu Val Ser Pro Gly Leu Pro Leu Phe Leu Ser Leu Asn Leu Arg Ala
         115                 120                 125            
 Glu Leu Pro Gly Met Phe Ile Lys Asp Leu Gln Tyr Pro Arg Tyr Trp
     130                 135                 140                
 Gly Asn Ser Gly Asn Arg Thr Phe Leu Ala Pro Ala Ala Ser Ile Asp
 145                 150                 155                 160
 Ile Ala Pro Glu Ala Met Glu Val Leu Gln Leu Gly Thr Leu Asn His
                 165                 170                 175    
 Arg Gln Leu Gln Ser Lys Leu Lys Ser Arg Thr Thr Leu Glu Gly Cys
             180                 185                 190        
 Thr Pro Leu Glu Gly Thr Gln Gly Arg Glu Ala Gly Ile Cys
         195                 200                 205    



      <210> 1445
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 1445
 Met Ala Ser Glu Thr Leu Pro Gly Gly Ser Ile Met Leu Leu Gly Val
   1               5                  10                  15    
 Met Leu Lys Pro Phe Val Phe Leu Glu Ser Val Val Arg Leu Val Met
              20                  25                  30        
 Asp Glu Gly Tyr Leu Met Gly Asn Gly Pro Pro Ile Arg Glu Val Val
          35                  40                  45            
 Ser Glu Lys Tyr Ser Cys Glu Glu Asn Thr Glu Glu Asn Lys Glu Ser
      50                  55                  60                
 Arg Leu Met Val Leu Thr Leu Glu Ser Val Glu Glu Asn Arg Ala Leu
  65                  70                  75                  80
 Thr Ala Ala Glu Gly Met Thr Tyr Ser Phe Ala Gly Phe Leu Arg Phe
                  85                  90                  95    
 Gln Ala Asn Thr Leu Tyr Ile Leu Asp Trp Trp Ser Gln Arg Glu Ala
             100                 105                 110        
 Gly Ala Gly Ala Tyr Arg Leu Gly Pro Ala Ser Pro Gln Gly Thr Leu
         115                 120                 125            
 Leu Gly Asp Lys Ala Arg Gly Pro Gly Gln Gly His Arg Gly Gly Ala
     130                 135                 140                
 Phe Pro Asp Ala Asp Asp Val Ala Val Leu Thr Asp Gly Lys Glu Asn
 145                 150                 155                 160
 Gly Cys Ser Pro Ser Ser Ile Thr Ser Ser Gly Leu Trp Thr Thr Arg
                 165                 170                 175    
 Pro Arg Ile Pro Gly Gly Gly Pro
             180                



      <210> 1446
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1446
 Met Arg Pro Tyr Ala Ala Leu Gly Val Thr Trp Ile Leu Gly Ala Gly
   1               5                  10                  15    
 Leu Leu Val Glu Ile Tyr Thr Asp Trp Ala Asn His Tyr Leu Ala Lys
              20                  25                  30        
 Ser Gly His Lys Arg Leu Ile Arg Asp Leu Gln Gln Asp Val Thr Asp
          35                  40                  45            
 Gly Val Leu Leu Ala Gln Ile Ile Gln Val Val Ala Pro Cys His Met
      50                  55                  60                
 Gly Leu Pro Ile Ser Ala Cys Phe Leu Asn Ala Ser Met Gly Glu Ser
  65                  70                  75                  80
 Phe Trp Asn Lys Ser Ala Asn Lys Met Thr Thr Leu Pro Gln Leu Ser
                  85                  90                  95    
 Leu Glu Asp Gly Ser Ser Met Thr Asn Glu Lys Ile Glu Asp Ile Asn
             100                 105                 110        
 Gly Cys Pro Lys Asn Arg Ser Gln Met Asn Thr Arg Ile
         115                 120                 125



      <210> 1447
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1447
 Met Gly Ile Ser Leu Thr Phe Phe Arg Ser Ser Ala Leu Arg Ala Ser
   1               5                  10                  15    
 Val Ser Leu Leu Leu Pro Leu Ser Glu Pro Arg Asp Val Pro Arg Ala
              20                  25                  30        
 Val Arg Pro Leu Phe Val Ser Leu Phe Asp Val Pro Gly Pro Arg Asn
          35                  40                  45            
 Gln Val Ile Thr Val Ala Arg Ile Ile Gly Lys Leu Arg Asn His Pro
      50                  55                  60                
 Val Gly Ile Thr Glu Pro Ala Gly Ser Pro Ser Trp Ala Ser Leu Leu
  65                  70                  75                  80
 Ala Pro Cys Tyr Arg Arg Pro Gly His Pro Arg Gln Gly Pro Ser Asp
                  85                  90                  95    
 Pro Ala Ser Pro His Pro Leu
             100            



      <210> 1448
      <211> 100
      <212> PRT
      <213> Homo sapiens


      <400> 1448
 Met Thr Cys Ser Asn His Arg Leu Ser Lys Arg Ala Pro Ser Leu Arg
   1               5                  10                  15    
 Leu Ala Leu Trp Val Phe Ala Phe Gln Pro Asn Leu Leu Arg Ile Ala
              20                  25                  30        
 Arg Gly Gly Thr Val Val Phe Leu Thr Gln Trp Ala Val Pro Ala Pro
          35                  40                  45            
 Leu Ser Cys Thr Gly Asn Ser Arg Leu Arg Val Gln Trp Arg Arg Lys
      50                  55                  60                
 Ala Gly Thr Leu Leu Asp Ser Leu Ser Asn Thr Gly Ile Glu Gly Val
  65                  70                  75                  80
 Cys Leu Val Glu Leu Asn Asn Val Gly Glu Lys Gln Val Glu Asn Leu
                  85                  90                  95    
 Gln Gly Ala Ala
             100



      <210> 1449
      <211> 152
      <212> PRT
      <213> Homo sapiens


      <400> 1449
 Met Pro Ala Ser Leu Val Val Phe Leu Cys His Cys Ser Met Gln Val
   1               5                  10                  15    
 Ala Phe Gly Ala Ala Asp Cys Met Arg Gln Gly Asn Asp His Gly Thr
              20                  25                  30        
 Gln Tyr Arg Ser Ala Ile Tyr Pro Thr Ser Ala Lys Gln Met Glu Ala
          35                  40                  45            
 Ala Leu Ser Ser Lys Lys Asn Tyr Gln Lys Ser Gly Thr Ala Met Glu
      50                  55                  60                
 His Gly Thr Ala Thr Glu His Gly Phe Leu Pro Ile Arg Val Leu His
  65                  70                  75                  80
 Arg Glu Leu Leu Ser Pro Phe Pro Ala Trp Arg Pro Gln His Glu Gly
                  85                  90                  95    
 Gln Val Phe Ser Phe Ser Gly Thr Lys Val Ser Leu Cys Val Pro His
             100                 105                 110        
 Pro Asp Glu Ser Ala Trp Gly Tyr Ser Ser Glu Gln Ile Ser Ala Asn
         115                 120                 125            
 Val Ala Met Glu Arg Lys Gly Ala Ser Val Leu Phe Trp Asp Val Leu
     130                 135                 140                
 Ser His Thr Leu Val Gly Arg Ser
 145                 150        



      <210> 1450
      <211> 249
      <212> PRT
      <213> Homo sapiens


      <400> 1450
 Met Ala Ala Met Leu Glu Asn Leu Leu Phe Val Phe Leu Leu Val Gly
   1               5                  10                  15    
 Ala Gly Leu Phe Cys Thr Met Glu Pro Glu Pro Val Gln Pro Gly Met
              20                  25                  30        
 Leu Ile Asp Val Cys Lys Tyr Leu Gly Ser Leu Gln Tyr Arg Val Trp
          35                  40                  45            
 Lys Lys Met Leu Ala Ser Val Glu Ser Val Pro Phe Ser Phe Asp Pro
      50                  55                  60                
 Asn Thr Ala Ala Gly Trp Leu Ser Val Ser Asp Asp Leu Thr Ser Val
  65                  70                  75                  80
 Thr Asn His Gly Tyr Arg Val Gln Val Glu Asn Pro Glu Arg Phe Ser
                  85                  90                  95    
 Ser Ala Pro Cys Leu Leu Gly Ser Arg Val Phe Ser Gln Gly Ser His
             100                 105                 110        
 Ala Trp Glu Val Ala Leu Gly Gly Leu Gln Ser Trp Arg Val Gly Val
         115                 120                 125            
 Val Arg Val Arg Gln Asp Ser Gly Ala Glu Gly His Ser His Ser Cys
     130                 135                 140                
 Tyr His Asp Thr Arg Ser Gly Phe Trp Tyr Val Cys Arg Thr Gln Gly
 145                 150                 155                 160
 Val Glu Gly Asp His Cys Val Thr Ser Asp Pro Ala Thr Ser Pro Leu
                 165                 170                 175    
 Val Leu Ala Ile Pro Arg Arg Leu Arg Val Glu Leu Glu Cys Glu Glu
             180                 185                 190        
 Gly Glu Leu Ser Phe Tyr Asp Ala Glu Arg His Cys His Leu Tyr Thr
         195                 200                 205            
 Phe His Ala Arg Phe Gly Glu Val Arg Pro Tyr Phe Tyr Leu Gly Gly
     210                 215                 220                
 Ala Arg Gly Ala Gly Pro Pro Glu Pro Leu Arg Ile Cys Pro Leu His
 225                 230                 235                 240
 Ile Ser Val Lys Glu Glu Leu Asp Gly
                 245                



      <210> 1451
      <211> 168
      <212> PRT
      <213> Homo sapiens


      <400> 1451
 Met Phe Pro Leu Ile Ser Ser His His Leu Trp Trp Gly Gly Leu Arg
   1               5                  10                  15    
 Arg Thr Val Cys Leu Asn Leu Pro Val Leu Thr Leu Gln His Phe Gln
              20                  25                  30        
 His Met His Ile Lys Val Gly Asp Arg Ala Glu Leu Arg Arg Ala Phe
          35                  40                  45            
 Thr Gln Thr Asp Val Ala Thr Phe Ser Glu Leu Thr Gly Asp Val Asn
      50                  55                  60                
 Pro Leu His Leu Asn Glu Asp Phe Ala Lys His Thr Lys Phe Gly Asn
  65                  70                  75                  80
 Thr Ile Val His Gly Val Leu Ile Asn Gly Leu Ile Ser Ala Leu Leu
                  85                  90                  95    
 Gly Thr Lys Met Pro Gly Pro Gly Cys Val Phe Leu Ser Gln Glu Ile
             100                 105                 110        
 Ser Phe Pro Ala Pro Leu Tyr Ile Gly Glu Val Val Leu Ala Ser Ala
         115                 120                 125            
 Glu Val Lys Lys Leu Lys Arg Phe Ile Ala Ile Ile Ala Val Ser Cys
     130                 135                 140                
 Ser Val Ile Glu Ser Lys Lys Thr Val Met Glu Gly Trp Val Lys Val
 145                 150                 155                 160
 Met Val Pro Glu Ala Ser Lys Ser
                 165            



      <210> 1452
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 1452
 Met Val Thr Glu Ala Ala Thr Gly Leu Leu Leu Thr Thr Leu Gln Gly
   1               5                  10                  15    
 Leu Phe Leu Val Thr Asp Asp Ser Cys Cys Leu Ser Ala Ile Gly His
              20                  25                  30        
 Thr Ile Gln Phe Ser Leu Ala Lys Gln Gln Leu Pro Ala Leu Gly Thr
          35                  40                  45            
 Lys Val Asp Ala Arg Ala Val Gly Val Gly His Thr Glu Leu Pro Phe
      50                  55                  60                
 Met Cys Val Gln Ser Gly Lys Leu Gly Lys Tyr Lys Thr Gln Thr Gln
  65                  70                  75                  80
 Leu Met Glu
            



      <210> 1453
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 1453
 Met Lys Asp Phe Ala Glu Phe Lys Gln Arg Lys Ala Asn Cys Val Met
   1               5                  10                  15    
 Arg Leu Val Thr Val Trp Ile Leu Asn Pro Leu Phe Cys His Ala Leu
              20                  25                  30        
 Trp Lys Phe Leu Leu Tyr Phe Ile Glu Trp Asp Ala Ala Pro Ile His
          35                  40                  45            
 Glu Ser Gln Ile Lys Ala Asn Ser Ile
      50                  55        



      <210> 1454
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1454
 Met Leu Gln Ala Leu Leu Gln Ala Leu Ser Ile Leu Thr Ile Thr Ala
   1               5                  10                  15    
 Gly Gly Leu Ser Tyr Asp Gly Pro Val Leu Gln Met Arg Thr Gln Glu
              20                  25                  30        
 Arg Glu Val Thr Lys Gly Trp Trp Leu Val Lys Gly Leu Leu Glu Ala
          35                  40                  45            
 Ala Glu Ala Val Pro Lys Arg Cys Tyr Trp Ser Pro Ile Ser Ile Leu
      50                  55                  60                
 Phe Ser Ser Ile Asn Lys Ile Thr Pro Lys Ala Trp Met His Thr Gly
  65                  70                  75                  80
 Gly Trp Ala Leu Glu Gln Pro Leu Cys Thr Gln Asn Trp Lys Ala Thr
                  85                  90                  95    
 Pro Thr Thr Gly Leu Leu Ala Leu Gln Gly Leu Ser Ala Gln Ser Thr
             100                 105                 110        
 Arg Gln Gln Cys Glu Arg Glu Lys Glu Arg Gln Arg Arg Val
         115                 120                 125    



      <210> 1455
      <211> 85
      <212> PRT
      <213> Homo sapiens


      <400> 1455
 Met Val Phe Cys Gln Thr Leu Val Ala Thr Val Cys Ala Phe Ser Glu
   1               5                  10                  15    
 Gln Leu Met Ala Ala Leu Asn Gln Met Phe Asp Asn Ser Lys Glu Asn
              20                  25                  30        
 Glu Met Glu Thr Trp Glu Ala Ser Arg Arg Trp Leu Asp Gln Ile Ala
          35                  40                  45            
 Asn Ala Gly Val Leu Phe His Phe Gln Ser Leu Leu Ser Pro Asn Leu
      50                  55                  60                
 Ser Lys Asp Thr Gly Cys Cys Glu Thr Lys Ala Pro Ile Glu Met Asp
  65                  70                  75                  80
 Val Leu Glu Gln Ala
                  85



      <210> 1456
      <211> 162
      <212> PRT
      <213> Homo sapiens


      <400> 1456
 Met Arg Leu Glu Val Leu Thr Leu Leu Leu Phe Leu Glu Arg Lys His
   1               5                  10                  15    
 Ser Ile Phe His His Glu Asp Glu Leu Asn Leu Ala Asp Ser Glu Val
              20                  25                  30        
 Asp Asn Gln Lys Arg Gly Lys Arg His Tyr Glu Glu Lys Gln Lys Glu
          35                  40                  45            
 His Leu Asp Thr Leu Asn Lys Lys Lys Arg Glu Leu Asp Met Lys Glu
      50                  55                  60                
 Lys Glu Leu Glu Glu Lys Met Ser Gln Ala Arg Gln Ile Cys Pro Glu
  65                  70                  75                  80
 Arg Ile Glu Val Glu Lys Ser Ala Ser Ile Leu Asp Lys Glu Ile Asn
                  85                  90                  95    
 Arg Leu Arg Gln Lys Ile Gln Ala Glu His Ala Ser His Gly Asp Arg
             100                 105                 110        
 Glu Glu Ile Met Arg Ala Gln Val Leu Lys Lys Glu Tyr Leu Asp Leu
         115                 120                 125            
 Asn Cys Ile Ser Thr Thr Tyr Leu Cys Asp Phe Gly Lys Leu Ala Ile
     130                 135                 140                
 Ser Leu Asn Phe Asn Phe Leu Ile His Lys Met Gly Ile Val Leu Lys
 145                 150                 155                 160
 Ile Lys
        



      <210> 1457
      <211> 256
      <212> PRT
      <213> Homo sapiens


      <400> 1457
 Met Ala Leu Ile Pro Leu Pro Ile Ser Phe Ser Leu Pro Leu Ala Ala
   1               5                  10                  15    
 Leu Trp Ala Thr Ala Phe Ala Ile Leu Gln Val Ala Trp Pro Asp Leu
              20                  25                  30        
 Leu Gly Pro His Pro Leu Arg Glu Leu Arg Asp Thr Gly Ser Gly His
          35                  40                  45            
 Thr Gln Cys Asp Phe His Met Met Ala Ala Gly Pro Asp Phe Val Val
      50                  55                  60                
 Met Ser Arg Pro Leu Asn Glu Gly Pro Asp His Asn Gln Asn Ala Gly
  65                  70                  75                  80
 Ser Val Ser Cys Tyr Leu Gln Asn Pro Ile His Lys Arg Glu Phe Cys
                  85                  90                  95    
 Leu Leu Val Gly Glu Arg Ser Ala Leu Glu His Leu Ser Thr Glu Leu
             100                 105                 110        
 Asp Glu Phe Lys Gly Tyr Thr Arg Gln Gln Phe Cys His Glu Ser Thr
         115                 120                 125            
 Pro Asn Lys Gly Val Arg Val Ile Tyr Asn Pro Thr His Pro Pro Tyr
     130                 135                 140                
 Cys Cys Ala Gln Phe Pro Leu Ala Ala Thr Gly Pro His Ile Leu Tyr
 145                 150                 155                 160
 Ser Ser Asn Ser Glu Leu Phe Lys Arg Gly Lys Gly Arg Gly Glu Gln
                 165                 170                 175    
 Arg Lys Glu Glu Val Thr Trp Asn Ala Glu Lys Val Trp Glu Val Arg
             180                 185                 190        
 Ser Ala Ser Val Arg Leu Pro Thr Val Gly Glu Val Arg Ser Ala Ser
         195                 200                 205            
 Pro Gln Leu Leu Pro Cys Leu Gly Ser Glu Glu His Leu Cys Pro Ala
     210                 215                 220                
 Ala His Cys Trp Gln Met Arg Ser Ala Ser Ala Arg Pro Pro Pro His
 225                 230                 235                 240
 Leu Gly Cys Glu Glu Arg Val Cys Pro Ala Ala Ala Leu Phe Gly Lys
                 245                 250                 255    





      <210> 1458
      <211> 307
      <212> PRT
      <213> Homo sapiens


      <400> 1458
 Met Ala Ala Met Val Leu Gly Thr Leu Tyr Cys Ile Ser Cys Leu Val
   1               5                  10                  15    
 Leu Ala Leu Gly Val Lys Glu Gln Leu Gly Gly Gln Gln Ala Ile Ser
              20                  25                  30        
 Ala Ala Val Ser Gly Asn Ile Gly Ser Trp Ser Arg Arg Cys Val Pro
          35                  40                  45            
 Pro Val Leu Phe Pro Trp Pro Leu Asp Ser Asp Ser Val Gly His Lys
      50                  55                  60                
 Lys Ser Asp Pro Ile Arg Ile Ile Asn Phe His Met Leu Asn Lys Asn
  65                  70                  75                  80
 Val Cys Met Glu Met Leu Asn Arg Leu Glu Ala Gln Arg Lys Gly Arg
                  85                  90                  95    
 Arg Thr Lys Gln Val Thr Arg Gln Thr Gln Leu Tyr Pro Glu Ala Ser
             100                 105                 110        
 Gly Leu Pro Glu Val Ser Gly Leu Leu Gly Phe Arg Ser Leu Phe Arg
         115                 120                 125            
 Arg Pro Gly Phe Pro Gly Arg Arg Ala Pro Cys Gly Ala Arg Thr Gln
     130                 135                 140                
 Gly Trp Ala Arg Arg Ala Glu Val Leu Gly Arg Ala Val Glu Pro Pro
 145                 150                 155                 160
 Pro Gly Arg Cys Trp Ser Thr Pro Pro Val Ala Pro Pro Ala Arg Ser
                 165                 170                 175    
 Ala Ser Ala Ala Ala Met Gly Val Gln Val Glu Thr Ile Ser Pro Gly
             180                 185                 190        
 Asp Gly Arg Thr Phe Pro Lys Arg Gly Gln Thr Cys Val Val His Tyr
         195                 200                 205            
 Thr Gly Glu Ser His Trp Leu Ala Trp Leu Leu Met Pro Ala Pro Ala
     210                 215                 220                
 Pro Pro Thr His Ala Pro Ser Gly Tyr Cys Val Asp Asn Gly Leu Leu
 225                 230                 235                 240
 Gly Ala Lys Ala Glu Thr Gly His Trp Leu Tyr Pro Ser Leu Cys Gln
                 245                 250                 255    
 Leu Cys Asp Thr His Leu Ile Thr Tyr His Pro Thr His Phe Gly Gly
             260                 265                 270        
 Leu Leu Phe Ser Phe Arg Thr Arg Leu Trp Glu Ile Leu Ser Leu Asp
         275                 280                 285            
 Ser Arg Asn Pro Asn Ile Thr Ala Thr Thr Gln Pro Cys Pro Ala Lys
     290                 295                 300                
 Ile Ser Pro
 305        



      <210> 1459
      <211> 42
      <212> PRT
      <213> Homo sapiens


      <400> 1459
 Met Ala Phe Glu Leu Arg Ala Pro Leu His Phe Val Tyr Ala Ile Gly
   1               5                  10                  15    
 Gln Leu Ile Val Leu Cys Asn Ser Asp Gln Ser Thr Cys Leu Gln Ile
              20                  25                  30        
 Val Thr Ile Leu Pro Phe Ser His Pro Arg
          35                  40        



      <210> 1460
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 1460
 Met Ser Gln Met His Phe Cys Leu Leu Gln Ile Met Tyr Gly Val Val
   1               5                  10                  15    
 Phe Cys Asp Glu His Ser Ala Val Pro Gly Pro Ser Cys Gln Asp Ser
              20                  25                  30        
 Gln Leu Ile Gly Ala Cys Ile Asp Cys Ser Leu Leu Phe Leu Gln Asn
          35                  40                  45            
 Pro Tyr Pro Ser Ile His Pro Ser Ile His Pro Ser Ile His Pro Ser
      50                  55                  60                
 Ile Gln Leu Ser Ile Tyr Pro Ser Ile Leu Pro Ser Ile Gln Ser Thr
  65                  70                  75                  80
 Cys Val Leu Asn Val Tyr Tyr Glu Pro Leu Ala Thr Arg Asn Pro Thr
                  85                  90                  95    
 Ser Thr Gln Ile Ile Arg Val Thr Glu Ser Leu Ile Arg Ile Leu Lys
             100                 105                 110        
 Glu Gly Glu Thr Val Gly Thr Gly Ser Thr Pro Gln Ser Leu Val Asn
         115                 120                 125            
 Asn Phe Leu Leu Ser Phe Ile Asn Ile Ala Met Ile Glu Met Thr Phe
     130                 135                 140                
 His Glu Gln Gln Gly Arg Ile Val Glu Glu Asn Glu Lys Leu Ser Leu
 145                 150                 155                 160
 Met Gln Leu Glu Pro Gly Ile Cys Cys Gly Glu Gly Val Ala Glu Val
                 165                 170                 175    
 Tyr Ser Asp Ser Phe Glu Ala Leu Lys Ile Leu Lys Val Lys Ala Leu
             180                 185                 190        
 Gln Thr His Ala Val Lys Pro Leu Val Arg Phe Leu Ser Lys Arg Leu
         195                 200                 205            





      <210> 1461
      <211> 214
      <212> PRT
      <213> Homo sapiens


      <400> 1461
 Met Val Val Thr Val Met Met Val Val Met Val Met Met Val Thr Ile
   1               5                  10                  15    
 Val Val Met Met Met Val Val Leu Val Ile Val Met Lys Leu Leu Val
              20                  25                  30        
 Met Thr Thr Asn Thr Trp Ala Asp Ser Cys Ile Ala Val Ala Ile Cys
          35                  40                  45            
 Gln Val Leu Tyr Glu Val Thr Met Asn Ala Cys Tyr Met Pro Gly Gly
      50                  55                  60                
 Met Trp Pro Val Asn Gly Val His Ser Arg Gly Asp Val Arg Tyr Arg
  65                  70                  75                  80
 Cys Gln Phe Val Thr Asp Glu Ser Thr Asp Ser Pro Arg Val Phe Ile
                  85                  90                  95    
 Met Glu Ala Cys Ala Pro Asp Cys Ala Gln His Asn Ser Trp Ala Ala
             100                 105                 110        
 Arg Val Gly Gln Gly Arg Ala Asn Asp Thr Phe Pro Leu Ala Lys Glu
         115                 120                 125            
 Asp Thr Pro Glu Ala Lys Cys Ser Met Arg Gln Pro Gly Ile Gln Ala
     130                 135                 140                
 Thr Ser Ser Val Ala Gly Arg Gln Pro Gly Ala Phe Ser Glu Glu Lys
 145                 150                 155                 160
 Gly Pro Val Ile Ile Pro Gln Met Leu Ser Glu Leu Trp Ala Gln Gly
                 165                 170                 175    
 Asn Arg Pro Ile Met Val Leu Pro Glu Gly Leu His Leu Leu Tyr Thr
             180                 185                 190        
 Arg His Lys Ile Arg Leu Pro Arg Glu Glu Pro Ser Asp Ser Val Gln
         195                 200                 205            
 Arg Ala His Val Thr Ile
     210                



      <210> 1462
      <211> 269
      <212> PRT
      <213> Homo sapiens


      <400> 1462
 Met Pro Arg Gln Asp Leu Pro Arg Ser Arg Leu Gly Phe Leu Gly Leu
   1               5                  10                  15    
 Gly Gly Cys Gly Leu Ile Val Lys His Gly Met Thr Leu Arg Asn Trp
              20                  25                  30        
 Ala Ser Phe Phe Val Val Phe Gln Ala Trp Ser Leu Met Ile Leu Gln
          35                  40                  45            
 Val Leu Gly Asp Met Leu Asn Ile Tyr Tyr Ala Tyr Ile Gln Ala Thr
      50                  55                  60                
 Leu Thr Leu Lys Val Asp Val Ala Pro Arg Leu Phe Phe Pro Glu Gly
  65                  70                  75                  80
 Gly Ala Leu Lys Glu His Phe Ser Ser Met Asp Ser Phe Gln Leu Arg
                  85                  90                  95    
 Glu Ala Gly Gly Thr Arg Ile Pro Arg Pro Ala Leu Ile Tyr Gly Arg
             100                 105                 110        
 Ala Val Val Thr Arg Thr Val Thr Lys Ala Gln Ser Leu Arg Ser Ala
         115                 120                 125            
 Leu Ala Trp Ala Ala Leu Gly Cys Lys His Pro Val Leu Ser Thr Leu
     130                 135                 140                
 Cys Glu Glu Ser Gln Gln Gly Ala Trp Thr Glu Met Ala Ala Pro Arg
 145                 150                 155                 160
 Trp Gly Val Cys Ser Ala Cys Ser Pro Arg Pro Pro Asp Ser Val Arg
                 165                 170                 175    
 Leu Arg Ser Gln Val Cys Thr Ser Ser Leu Ser Ser Asn Phe Ala Ser
             180                 185                 190        
 Leu Asp Cys Val Thr Tyr Lys Ala Leu Ser Thr Thr Arg Leu Tyr Asp
         195                 200                 205            
 Ser Val Tyr Trp Asn Lys Lys Pro Val Arg Gln Val Tyr His Pro Val
     210                 215                 220                
 Asp Glu Phe Thr Ala Leu Thr Leu Gly Val Gly Asp Ser Val Tyr Ser
 225                 230                 235                 240
 Ser Ser Arg His Ser Leu Phe Leu Leu Asp Gly Lys Val Leu Leu Leu
                 245                 250                 255    
 Val Pro Trp Ser Gly Pro Ala Asn Gly Thr Glu Trp Lys
             260                 265                



      <210> 1463
      <211> 267
      <212> PRT
      <213> Homo sapiens


      <400> 1463
 Met Val Leu Asn Phe Trp Ala Leu Met Ile Leu Ser Pro Gly Ser Gly
   1               5                  10                  15    
 Val Thr Ile Phe Ser Ser Thr Phe Leu Leu Thr Arg Glu Asn Pro Thr
              20                  25                  30        
 Arg Leu Pro Pro Phe Cys Pro Ser Trp Pro Pro Pro Asn Val Leu Phe
          35                  40                  45            
 Pro Ser Leu Gly Arg Leu Arg Ala Pro Ser Phe Pro Pro Thr Pro Ala
      50                  55                  60                
 Arg Val Gln Asn His Glu Pro Gly Thr Leu His Leu Leu Leu Arg Ala
  65                  70                  75                  80
 Phe Trp Ser Ile Pro Val Gly Arg Val Pro Val Leu Thr Ser Val Ala
                  85                  90                  95    
 Gln Ser Ser Leu His Glu Glu Ile Ser Asp Phe Tyr Glu Tyr Met Ser
             100                 105                 110        
 Pro Arg Pro Glu Glu Glu Lys Met Arg Met Glu Val Val Asn Arg Ile
         115                 120                 125            
 Glu Ser Val Ile Lys Glu Leu Trp Pro Ser Ala Asp Val Gln Ile Phe
     130                 135                 140                
 Gly Ser Phe Lys Thr Gly Leu Tyr Leu Pro Thr Ser Asp Ile Asp Leu
 145                 150                 155                 160
 Val Val Phe Gly Lys Trp Glu Asn Leu Pro Leu Trp Thr Leu Glu Glu
                 165                 170                 175    
 Ala Leu Arg Lys His Lys Val Ala Asp Glu Asp Ser Val Lys Val Leu
             180                 185                 190        
 Asp Lys Ala Thr Val Pro Ile Ile Lys Leu Thr Asp Ser Phe Thr Glu
         195                 200                 205            
 Val Lys Val Asp Ile Ser Phe Asn Val Gln Asn Gly Val Arg Ala Ala
     210                 215                 220                
 Asp Leu Ile Lys Asp Phe Thr Lys Ala Ala Gly Cys Thr Ser Met Ala
 225                 230                 235                 240
 Leu Glu Ser Ala Ser Gly Glu Gly Leu Arg Lys Leu Thr Ile Thr Val
                 245                 250                 255    
 Gly Ala Glu Gly Gly Ala Gly Met Leu His Lys
             260                 265        



      <210> 1464
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 1464
 Met Ala Ala Phe Ala Gly Thr Ala Ile Leu Leu Met Asp Phe Gly Val
   1               5                  10                  15    
 Thr Asn Arg Asp Val Asp Arg Gly Tyr Leu Ala Val Leu Thr Ile Phe
              20                  25                  30        
 Thr Val Leu Glu Phe Phe Thr Ala Val Ile Ala Met His Phe Gly Cys
          35                  40                  45            
 Gln Ala Ile His Ala Gln Ala Ser Ala Pro Val Ile Phe Leu Pro Asn
      50                  55                  60                
 Ala Phe Ser Ala Asp Phe Asn Ile Pro Ser Pro Ala Ala Ser Ala Pro
  65                  70                  75                  80
 Pro Ala Tyr Asp Asn Val Ala Tyr Ala Gln Gly Val Val
                  85                  90            



      <210> 1465
      <211> 128
      <212> PRT
      <213> Homo sapiens


      <400> 1465
 Met Leu Cys Ile Ala Ile His Ile Leu Phe Leu Leu Asn Arg Phe Ile
   1               5                  10                  15    
 Ala Asp Asn Gln Met Asn His Ala Cys Met Leu Phe Val Glu Asn Tyr
              20                  25                  30        
 Gly Gln Lys Ile Ile Lys Lys Asn Leu Cys Arg Asn Phe Met Leu His
          35                  40                  45            
 Leu Val Ser Met His Asp Phe Asn Leu Ile Ser Ile Met Ser Ile Asp
      50                  55                  60                
 Lys Ala Val Thr Lys Leu Arg Glu Met Gln Gln Lys Leu Glu Lys Gly
  65                  70                  75                  80
 Glu Ser Ala Ser Pro Ala Asn Glu Glu Ile Thr Glu Glu Gln Asn Gly
                  85                  90                  95    
 Thr Ala Asn Gly Phe Ser Glu Ile Asn Ser Lys Glu Lys Ala Leu Glu
             100                 105                 110        
 Thr Asp Ser Val Ser Gly Val Ser Lys Gln Ser Lys Lys Gln Lys Leu
         115                 120                 125            





      <210> 1466
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1466
 Met Leu Phe Ala Ala Phe Gly Arg Pro His Val Gly Ala Val His Leu
   1               5                  10                  15    
 Val Val Gly Cys Ala Trp Lys Glu Lys Trp Leu Asp Val Arg Ala His
              20                  25                  30        
 Thr Asp Ser Pro Thr Val Ala Asn Asp Leu Pro Gly Glu Ser Gly Thr
          35                  40                  45            
 Trp Lys Glu His Asp Trp Lys Ile Ser Asp Lys Glu Thr Glu Gly Thr
      50                  55                  60                
 Glu Arg Arg Asp Thr Leu Asp Arg Asp Leu Pro Ser Leu Tyr Val Thr
  65                  70                  75                  80
 Leu Leu Pro Lys Leu Ala Ser Val Asp Ser Gln Asn Ala Val Pro Thr
                  85                  90                  95    
 Val Thr Val Cys His Thr Ala Leu Leu Leu Ser Glu Glu Leu Pro Ser
             100                 105                 110        
 Gln Gln Arg Lys Tyr Gly Asn Glu Pro Met Leu Met Glu Phe Pro Gly
         115                 120                 125            
 Thr Thr Met Leu Pro Thr Ile Leu Lys Gln Leu Val
     130                 135                 140



      <210> 1467
      <211> 249
      <212> PRT
      <213> Homo sapiens


      <400> 1467
 Met Thr Cys His Leu Gly Trp Leu Ala Glu Ile Arg Leu Trp Leu Gln
   1               5                  10                  15    
 Val Trp Val Gly Ala Ser Leu Pro Asn Asp Leu Met Pro Asp His Phe
              20                  25                  30        
 Arg Asp Ile Gly Leu Gly Tyr Pro Asn His Ile Leu Ala Gln Pro Gly
          35                  40                  45            
 Gln Leu Gln Arg Phe Lys Arg Ser Leu Ser Leu Lys Thr Ile Leu Arg
      50                  55                  60                
 Ser Lys Ser Leu Glu Asn Phe Phe Leu Arg Ser Gly Ser Glu Leu Lys
  65                  70                  75                  80
 Cys Pro Thr Glu Val Leu Leu Thr Pro Pro Thr Pro Leu Pro Pro Pro
                  85                  90                  95    
 Ser Pro Pro Pro Thr Ala Ser Asp Arg Gly Leu Ala Thr Pro Ser Pro
             100                 105                 110        
 Ser Pro Cys Pro Val Pro Arg Pro Leu Ala Ala Leu Lys Pro Val Arg
         115                 120                 125            
 Leu His Ser Phe Gln Glu His Val Phe Lys Arg Ala Ser Pro Cys Glu
     130                 135                 140                
 Leu Cys His Gln Leu Ile Val Gly Asn Ser Lys Gln Gly Leu Arg Cys
 145                 150                 155                 160
 Lys Met Cys Lys Val Ser Val His Leu Trp Cys Ser Glu Glu Ile Ser
                 165                 170                 175    
 His Gln Gln Cys Pro Gly Lys Thr Ser Thr Ser Phe Arg Arg Asn Phe
             180                 185                 190        
 Ser Ser Pro Leu Leu Val His Glu Pro Pro Pro Val Cys Ala Thr Ser
         195                 200                 205            
 Lys Glu Ser Pro Pro Thr Asp Val Val Thr Leu Cys Arg Cys Ala Gln
     210                 215                 220                
 Val Ser Arg Ser Trp Arg Leu Asn Phe Ser Arg Asp Gly Gly Ser Val
 225                 230                 235                 240
 Leu Thr Pro Lys Val Pro Lys Leu Leu
                 245                



      <210> 1468
      <211> 396
      <212> PRT
      <213> Homo sapiens


      <400> 1468
 Met Gln Leu Leu Arg Glu Trp Pro Gly Val Ile Leu Arg Ala Gly Thr
   1               5                  10                  15    
 Thr Leu Ser Val Leu Pro Trp Ala Leu Gln Glu Arg Trp Arg Val Thr
              20                  25                  30        
 Ala Glu Gln Ser Lys Ala Glu Ser Met Gln Arg Ala Leu Glu Glu Gln
          35                  40                  45            
 Arg Lys Val Thr Ala Gln Gln Met Ala Met Glu Arg Ala Glu Leu Glu
      50                  55                  60                
 Arg Ala Lys Ser Ala Leu Leu Glu Glu Gln Lys Ser Val Met Leu Lys
  65                  70                  75                  80
 Cys Gly Glu Glu Arg Arg Arg Leu Ala Ala Glu Trp Ala Glu Phe Ser
                  85                  90                  95    
 Ala Gln Gln Lys Leu Ser Lys Glu Arg Ala Glu Arg Glu Ala Glu Arg
             100                 105                 110        
 Ala Leu Gln Val Asp Thr Gln Arg Glu Gly Thr Leu Ile Ser Leu Ala
         115                 120                 125            
 Lys Glu Gln Ala Glu Leu Lys Ile Arg Ala Ser Glu Leu Arg Ala Glu
     130                 135                 140                
 Glu Lys Gln Leu Ala Ala Glu Arg Ala Ala Leu Glu Gln Glu Arg Gln
 145                 150                 155                 160
 Glu Leu Arg Leu Glu Lys Glu Arg Ile Asn Ala Thr Ala Leu Arg Val
                 165                 170                 175    
 Lys Leu Arg Ala Glu Glu Val Glu Ser Met Ser Lys Val Ala Ser Glu
             180                 185                 190        
 Lys Tyr Glu Glu Gly Glu Arg Ala Leu Arg Glu Ala Gln Gln Val Gln
         195                 200                 205            
 Ala Glu Gln Gln Ala Arg Leu Gln Ala Val Gln Gln Gln Gln Glu Arg
     210                 215                 220                
 Leu Arg Lys Gln Arg Gln Arg Met Arg Glu Gly Glu Arg Gly Val Pro
 225                 230                 235                 240
 Pro Ala Lys Ala Pro Gln Tyr Trp Asp Ala Asp Ile Phe Arg Gly His
                 245                 250                 255    
 Thr Ala Pro Phe Trp Leu Ser Val Val Leu Glu Ala Gln Lys Arg Lys
             260                 265                 270        
 Cys Thr Arg Gly Val Tyr Lys His Ser Asn Ser Arg Asn Cys Ser Glu
         275                 280                 285            
 Gln Ala Leu Gln Leu Cys Leu Gly Lys Leu Asn Leu Thr Glu Pro Gly
     290                 295                 300                
 Gly Pro Ser Gly Asn Phe Arg Val Gly Pro Ile Ser Ile Ala Thr Arg
 305                 310                 315                 320
 Asn Ser Pro Arg His Ala Leu Ala Leu Leu Leu Met Arg Glu Arg Ala
                 325                 330                 335    
 Ile Cys Val Leu Glu Ile Pro Thr Ala Lys Lys Asp Ser Ser Lys Ile
             340                 345                 350        
 Ala His Phe His Val Thr Lys His His Gln Arg Leu Thr Gly His Leu
         355                 360                 365            
 Pro Leu Arg Ser Arg Ala Thr Asn Gly Glu Trp Gln Lys Val Thr Asn
     370                 375                 380                
 Asp Leu Pro Gly Val Leu Phe Phe Ser Leu Ala Tyr
 385                 390                 395    



      <210> 1469
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 1469
 Met Arg Val Ile Val Ala Ser Ser Gln Met Arg Trp Leu Val Leu Thr
   1               5                  10                  15    
 Arg Ala His Val Met Lys Ser Ala Thr Cys Cys Ser Cys Val Arg Leu
              20                  25                  30        
 Thr Val Leu Asp Thr Ser Thr Leu Ile Ala Cys Pro Gln Tyr Val Phe
          35                  40                  45            
 Val His Tyr Val Phe His Val Ala Glu Ser Val Cys Arg His Arg Thr
      50                  55                  60                
 Leu Gln His Met His Ile Phe Cys Ser Met His Leu Ile Gln Thr Thr
  65                  70                  75                  80
 Met Glu Leu Phe Lys Thr Thr Glu Leu Lys Gln Phe Ser Val Ser Arg
                  85                  90                  95    
 Ala Leu Leu Ser Asn Pro Gly Leu Glu Ser Ser Lys Arg Gln Arg Gly
             100                 105                 110        
 Pro Ala Ala Leu Ala Thr Asp Gln Glu Ala Ser Arg Leu Gly Arg Glu
         115                 120                 125            
 Arg Arg Gln Asp Thr Cys Thr Arg Gly Ser Arg Leu Arg Gly Pro Val
     130                 135                 140                
 Pro Thr Ala Pro Leu Ser Arg Arg Asp Pro His Thr Ser Cys Pro Pro
 145                 150                 155                 160
 Pro Gly Gly Ala Tyr Asp Arg His Ser Val Gly Gln Gln Pro Arg Leu
                 165                 170                 175    
 Pro Pro Pro Ser Ala Cys Val Trp Gly Asn Glu Ala Pro Arg Gly Pro
             180                 185                 190        
 Pro Leu Asn Leu Val Ala Pro Arg Asn Asp Val Arg Arg Thr Leu Arg
         195                 200                 205            
 Arg Leu Asn Gln Trp
     210            



      <210> 1470
      <211> 264
      <212> PRT
      <213> Homo sapiens


      <400> 1470
 Met Ala Pro Ala Ser Arg Leu Leu Ala Leu Trp Ala Leu Ala Ala Val
   1               5                  10                  15    
 Ala Leu Pro Gly Ser Gly Ala Glu Gly Asp Gly Gly Trp Arg Pro Gly
              20                  25                  30        
 Gly Pro Gly Ala Val Ala Glu Glu Glu Arg Cys Thr Val Glu Arg Arg
          35                  40                  45            
 Ala Asp Leu Thr Tyr Ala Glu Phe Val Gln Gln Tyr Ala Phe Val Arg
      50                  55                  60                
 Pro Val Ile Leu Gln Gly Leu Thr Asp Asn Ser Arg Phe Arg Ala Leu
  65                  70                  75                  80
 Cys Ser Arg Asp Arg Leu Leu Ala Ser Phe Gly Asp Arg Val Val Arg
                  85                  90                  95    
 Leu Ser Thr Ala Asn Thr Tyr Ser Tyr His Lys Val Asp Leu Pro Phe
             100                 105                 110        
 Gln Glu Tyr Val Glu Gln Leu Leu His Pro Gln Asp Pro Thr Ser Leu
         115                 120                 125            
 Gly Asn Asp Thr Leu Tyr Phe Phe Gly Asp Asn Asn Phe Thr Glu Trp
     130                 135                 140                
 Ala Ser Leu Phe Arg His Tyr Ser Pro Pro Pro Phe Gly Leu Leu Gly
 145                 150                 155                 160
 Thr Ala Pro Ala Tyr Ser Phe Gly Ile Ala Gly Ala Gly Ser Gly Val
                 165                 170                 175    
 Pro Phe His Trp His Gly Pro Gly Tyr Ser Glu Val Ile Tyr Gly Arg
             180                 185                 190        
 Lys Arg Trp Phe Leu Tyr Pro Pro Glu Lys Thr Pro Glu Phe His Pro
         195                 200                 205            
 Asn Lys Thr Thr Leu Ala Trp Leu Arg Asp Thr Tyr Pro Ala Leu Pro
     210                 215                 220                
 Pro Ser Ala Arg Pro Leu Glu Cys Thr Ile Arg Ala Gly Glu Val Leu
 225                 230                 235                 240
 Tyr Phe Pro Asp Arg Trp Trp His Ala Thr Leu Asn Leu Asp Thr Ser
                 245                 250                 255    
 Val Phe Ile Ser Thr Phe Leu Gly
             260                



      <210> 1471
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1471
 Met Ala Leu Asp Phe Val Asn Val Leu Leu Cys Gln Leu Ala Glu Val
   1               5                  10                  15    
 Thr Leu Gly Val Leu Arg Glu Glu Gly Ala Ser Leu Leu Val Ala Leu
              20                  25                  30        
 Gly Ser Ala Leu Phe Pro Ser Ala Ala Ala Val Gly Lys Gln Gly Ser
          35                  40                  45            
 Met Gly Gly Cys Phe His Ser Ser Ser Glu Ser Glu Pro Arg Asp Gln
      50                  55                  60                
 Arg Asn Gly Pro Asn Asn Pro Glu Cys Asp Glu Lys Pro Leu Leu Pro
  65                  70                  75                  80
 Trp Leu
        



      <210> 1472
      <211> 43
      <212> PRT
      <213> Homo sapiens


      <400> 1472
 Met Ile Ala Ile Tyr Gly Thr Asn Phe Cys Thr Ser Ala Arg Asn Ala
   1               5                  10                  15    
 Phe Phe Leu Leu Met Arg Asn Ile Ile Arg Ser Gly Ile Ile Ile Ile
              20                  25                  30        
 Phe Leu Leu Pro Pro Ala Ser Ser Pro Ser Pro
          35                  40            



      <210> 1473
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1473
 Met Ala Ala Asn Thr Trp Leu Leu Ala Ser Met Trp Leu Gly Pro Leu
   1               5                  10                  15    
 Ser Thr Cys Pro Asn Lys Thr Ser Ala Asp Ile Gly Asp Ile Met Ser
              20                  25                  30        
 Ser Val Asn Tyr Ile Thr Arg Leu Ser Leu Thr His Ile Ser Asn Gly
          35                  40                  45            
 Ser Phe Gly Leu Leu Val Lys Val Thr Phe Thr Lys Leu Ser Ser Val
      50                  55                  60                
 Lys His Leu Ser Gly Phe Pro Glu Leu Ser Ala Ser Gly Phe Ser Ser
  65                  70                  75                  80
 Lys Arg Thr Leu Val Phe Ile Leu Pro Leu Ala Ala Pro Phe Ser Val
                  85                  90                  95    
 Gly Leu Glu Ala Cys Pro Leu Ala Gly Lys Arg Leu Lys Gly Ser Val
             100                 105                 110        
 Cys Pro Glu Leu Glu Phe Pro Leu Trp Lys Lys His Arg Val Phe Ser
         115                 120                 125            
 Gln Ser Leu Pro Tyr Lys Thr His Ala Phe Asn Glu Glu Arg Leu Gln
     130                 135                 140                
 Glu
 145



      <210> 1474
      <211> 188
      <212> PRT
      <213> Homo sapiens


      <400> 1474
 Met Leu Leu Thr Thr Val Leu Tyr Phe Pro Leu Asp Ala Lys Ala Cys
   1               5                  10                  15    
 Phe Gln Leu Phe Tyr Leu Ile Gln Ser Ser Leu Cys Lys Gly Arg Thr
              20                  25                  30        
 Leu Tyr Ser Val Val Arg Asp Ala Lys Ile Val Leu Asp Val Asn Lys
          35                  40                  45            
 Thr Arg Gln Ile Ala Gln Glu Ile Val Lys Gly Met Gly Tyr Leu His
      50                  55                  60                
 Ala Lys Gly Ile Leu His Lys Asp Leu Lys Ser Lys Asn Val Phe Tyr
  65                  70                  75                  80
 Asp Asn Gly Lys Val Val Ile Thr Asp Phe Gly Leu Phe Ser Ile Ser
                  85                  90                  95    
 Gly Val Leu Gln Ala Gly Arg Arg Glu Asp Lys Leu Arg Ile Gln Asn
             100                 105                 110        
 Gly Trp Leu Cys His Leu Ala Pro Glu Ile Ile Arg Gln Leu Ser Pro
         115                 120                 125            
 Asp Thr Glu Glu Asp Lys Leu Pro Phe Ser Lys His Ser Asp Val Phe
     130                 135                 140                
 Ala Leu Gly Glu Met Leu Ala Ala Phe Thr Glu Ser Glu Pro Val Gly
 145                 150                 155                 160
 Met Lys Ala Glu Asn Gly His Gln Gln His Pro Glu Glu Val Glu Ala
                 165                 170                 175    
 Ile Glu Leu Asp Asp Gly Leu Asn Leu Gly Gly Ala
             180                 185            



      <210> 1475
      <211> 430
      <212> PRT
      <213> Homo sapiens


      <400> 1475
 Met Leu Asp Leu Tyr Ala Gly Ala Leu Phe Val His Ile Cys Leu Gly
   1               5                  10                  15    
 Trp Asn Phe Tyr Leu Ser Thr Ile Leu Thr Leu Gly Ile Thr Ala Leu
              20                  25                  30        
 Tyr Thr Ile Ala Gly Gly Leu Ala Ala Val Ile Tyr Thr Asp Ala Leu
          35                  40                  45            
 Gln Thr Leu Ile Met Val Val Gly Ala Val Ile Leu Thr Ile Lys Gly
      50                  55                  60                
 Thr Ala Leu Ala Gly Arg Gly Tyr Pro Pro Cys Cys Pro Ala Val Thr
  65                  70                  75                  80
 Ser Ser Gly Pro Gly Lys Glu Leu Thr Gln Glu Leu Arg Ala Ser His
                  85                  90                  95    
 Thr Arg Ile Gly Ser Ala Leu Asp Ala Phe Asp Gln Ile Gly Gly Tyr
             100                 105                 110        
 Gly Gln Leu Glu Ala Ala Tyr Ala Gln Ala Ile Pro Ser Arg Thr Ile
         115                 120                 125            
 Ala Asn Thr Thr Cys His Leu Pro Arg Thr Asp Ala Met His Met Phe
     130                 135                 140                
 Arg Asp Pro His Thr Gly Asp Leu Pro Trp Thr Gly Met Thr Phe Gly
 145                 150                 155                 160
 Leu Thr Ile Met Ala Thr Trp Tyr Trp Cys Thr Asp Gln Val Leu Arg
                 165                 170                 175    
 Leu Arg Gln Phe Gly Val Trp Asp Ser Glu Gly Thr Arg Met Leu Leu
             180                 185                 190        
 Gly Gly Pro Ala Ile Gly His Gly Ala Gly Ile Leu Gly Gln Ser Trp
         195                 200                 205            
 Ala Ala Gly Ile Arg Lys Gln Ala Gly Tyr Leu Thr Ser Leu Gly Leu
     210                 215                 220                
 Pro Val Val Gly Ala Ser His Gly Trp Ala Ser Val Ser Gly Arg Ala
 225                 230                 235                 240
 Leu Asp Ala Val Ser Ser Arg Ala Val Ile Val Gln Arg Ser Leu Ser
                 245                 250                 255    
 Ala Arg Asp Leu Asn His Ala Lys Ala Gly Ser Ile Leu Ala Ser Tyr
             260                 265                 270        
 Leu Lys Met Leu Pro Met Gly Leu Ile Ile Met Pro Gly Met Ile Ser
         275                 280                 285            
 Arg Ala Leu Phe Pro Gly Met Pro Leu Arg Leu Thr Leu Cys Asp Met
     290                 295                 300                
 Arg Tyr Ser Ser Trp Asn Cys Arg Ser Asn Ile Ser Thr Thr Trp Pro
 305                 310                 315                 320
 Asp Ser Thr Glu Ile Thr Phe Arg Ser Val Arg Ala Ala Asp His Val
                 325                 330                 335    
 Lys Leu Gln Gln Arg Glu Gly Ala Leu Val Arg His Met Thr Leu Leu
             340                 345                 350        
 Pro Pro Pro Ser Pro Arg Ala Pro Ile Ala Ala Gly Pro Gln Thr Val
         355                 360                 365            
 Ala Thr Gly Pro Trp Asp Gln Glu Val Asn Gly Gly Arg Glu Gln Val
     370                 375                 380                
 Ala Gly Pro Ala Val Arg Glu Glu Gln Met Val Lys Ala Gly Ala Gly
 385                 390                 395                 400
 His Gly Arg Pro Gln Glu Gly Gln Gly Glu Pro Gly Trp Asn Pro Ser
                 405                 410                 415    
 Val Glu Asp Gly Gln Gly His Pro Glu Val Glu Ser Gln Val
             420                 425                 430



      <210> 1476
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 1476
 Met Asp Leu Trp Tyr Ser Cys Asn Leu Val Val Leu Pro Ala Leu Leu
   1               5                  10                  15    
 Glu Glu Leu Ala Gln Met Asn Ser Val Asp Ser Lys Ala Gln Ile Glu
              20                  25                  30        
 Gly Leu Ala Pro Asp Ala Cys Tyr Ala Arg Pro Gln Val Ile Thr Ile
          35                  40                  45            
 Asn His Thr Ala Ile Glu Gln Ala His Ser Gln Glu Val Ile Ala Ile
      50                  55                  60                
 Gln Pro Trp Asn Glu Lys Thr His Gly Glu Cys Ser Leu Arg Gly Asn
  65                  70                  75                  80
 Ser Gly Val Pro Asn Asp Ala Leu Ser Val Asp Trp Ala Ser Ser Ile
                  85                  90                  95    
 Thr Leu Ile Arg Val Lys Glu Arg Lys Ile Tyr Arg Glu Val Val Glu
             100                 105                 110        
 Ser Glu Ser Glu Asp Ser Leu Val Pro Glu Pro Val Leu Leu Asn Thr
         115                 120                 125            
 Val His Ala Ala Glu Lys Glu Lys Gln Val
     130                 135            



      <210> 1477
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1477
 Met Val Ala Trp Pro Cys Pro Met Ile Ala Glu Leu Leu Trp Thr Ala
   1               5                  10                  15    
 Pro Glu Leu Leu Pro Gly Pro Gly Arg Pro Gly Arg Arg Thr Leu Thr
              20                  25                  30        
 Gly Asp Ile Phe Ser Thr Gly Ile Ile Leu Gln Glu Val Leu Thr Arg
          35                  40                  45            
 Ala His Ser Thr Ala Pro Arg Asp Phe Gln Trp Lys Pro Ser Ala Thr
      50                  55                  60                
 Leu Pro Glu
  65        



      <210> 1478
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1478
 Met Met Ile Pro Leu Asn Trp Lys Leu Thr Leu Pro Pro Gly Leu Phe
   1               5                  10                  15    
 Gly Leu Leu Leu Pro Leu Ser Gln Gln Ala Lys Lys Gly Val Thr Val
              20                  25                  30        
 Leu Ala Gly Val Ile Gly Pro Asp Ser Gln Asp Glu Ile Ser Leu Leu
          35                  40                  45            
 Leu His Ser Gly Gly Lys Glu Glu Tyr Ala Trp Asn Thr Gly Gly Pro
      50                  55                  60                
 Leu Gly Gly Leu Leu Val Leu Pro Cys Pro Met Phe Lys Val Asn Gly
  65                  70                  75                  80
 Lys Leu Gln Gln Pro Asn Pro Asp Arg Thr Thr Lys Asp Pro Asp Pro
                  85                  90                  95    
 Ser Gly Met Lys Val Trp Ile Thr Leu Pro Gly Glu Lys Pro Gln Pro
             100                 105                 110        
 Ala Glu Val Leu Ala Glu Gly Lys Gly Asn Thr Glu Trp Val Val Glu
         115                 120                 125            
 Glu Cys Ser His Gln Tyr Gln Leu Gln Pro Arg Asp Gln Leu Gln Lys
     130                 135                 140                
 Arg Gly Leu
 145        



      <210> 1479
      <211> 189
      <212> PRT
      <213> Homo sapiens


      <400> 1479
 Met Pro Phe Leu Thr Leu Pro Trp Cys Leu Ala Gly Pro Pro Gly Leu
   1               5                  10                  15    
 Val Arg Asn Leu Gln Val Thr Asp Arg Ser Asn Thr Ser Ile Thr Leu
              20                  25                  30        
 Ser Trp Ala Gly Pro Asp Thr Gln Glu Gly Asp Glu Ala Gln Gly Tyr
          35                  40                  45            
 Val Val Glu Leu Cys Ser Ser Asp Ser Leu Gln Trp Leu Pro Cys His
      50                  55                  60                
 Val Gly Thr Val Pro Val Thr Thr Tyr Thr Ala Lys Gly Leu Arg Pro
  65                  70                  75                  80
 Gly Glu Gly Tyr Phe Val Arg Val Thr Ala Val Asn Glu Gly Gly Gln
                  85                  90                  95    
 Ser Gln Pro Ser Ala Leu Asp Thr Leu Val Gln Ala Met Pro Val Thr
             100                 105                 110        
 Val Cys Pro Lys Phe Leu Val Asp Ser Ser Thr Lys Asp Leu Leu Thr
         115                 120                 125            
 Val Lys Val Gly Asp Thr Val Arg Val Pro Val Ser Phe Glu Ser Val
     130                 135                 140                
 Leu Val Glu Ile Thr Asp Trp Ala Cys Gly Asn Gln Val Arg Asp Met
 145                 150                 155                 160
 Arg Gln Glu Gly Phe Arg Ser Ser Leu Lys Val Leu Pro Ser Leu Gly
                 165                 170                 175    
 Gly Trp Val Ala Ile Leu Leu Gln Ala Cys Lys Ser Leu
             180                 185                



      <210> 1480
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1480
 Met Gly Leu Met Gln Arg Thr Ala His Trp Ala Arg Ala Ser Pro Gly
   1               5                  10                  15    
 Gly Ile Leu Val Met Lys Ser Cys Ser Pro Thr Cys Pro Asn Ser Thr
              20                  25                  30        
 Val Ser Ser Asp Ser Arg Ala Leu Ser Val Ser Cys Cys Gln Gly Ser
          35                  40                  45            
 Gln Cys Asn Arg Ser Ala Ala Ala Gly Leu Val Gly Ser Pro Gly Thr
      50                  55                  60                
 Leu Trp Ala Ser Ile Ala Ala Ser Gln Leu Trp Ala Leu Leu Gln Ala
  65                  70                  75                  80
 Ala Arg
        



      <210> 1481
      <211> 163
      <212> PRT
      <213> Homo sapiens


      <400> 1481
 Met Met Val Val Leu Leu Gly Ala Thr Thr Leu Val Leu Val Ala Val
   1               5                  10                  15    
 Ala Pro Trp Val Leu Ser Ala Ala Ala Gly Glu Arg Arg Gly Gly Glu
              20                  25                  30        
 Ser Trp Arg Arg Ala Gly Gly Arg Ala Arg Ser Trp Ala Thr Gly Ala
          35                  40                  45            
 Ala Met Leu Leu Gly Ala Thr Asp Ala Gln Ser Gly Lys Pro Ser Val
      50                  55                  60                
 His Phe Ala Ala Pro Lys Ile Lys Pro Asp Leu Gly Ser Gln Ile Asn
  65                  70                  75                  80
 Gln Glu Lys Val Val Phe Trp Val Leu Ser Cys Arg Leu Pro Val Ala
                  85                  90                  95    
 Val Tyr Gly Ser Ser Gly Ala Pro Gly Ser His Pro Arg Glu Met Ala
             100                 105                 110        
 Val Pro Glu Leu Cys Val Glu Phe Asp Ser Phe Arg Glu Thr His Gln
         115                 120                 125            
 Ile Leu Leu Val Tyr Phe Val Cys Gly Pro Arg Gln Leu Phe Phe Gln
     130                 135                 140                
 Cys Gly Pro Arg Lys Pro Lys Arg Val Asp Thr Leu Asp Ala Asp Glu
 145                 150                 155                 160
 Ala Cys Arg
            



      <210> 1482
      <211> 222
      <212> PRT
      <213> Homo sapiens


      <400> 1482
 Met Leu Leu Cys Thr Ala Arg Leu Val Gly Leu Gln Leu Leu Ile Ser
   1               5                  10                  15    
 Cys Cys Trp Ala Phe Ala Cys His Ser Thr Glu Ser Ser Pro Asp Phe
              20                  25                  30        
 Thr Leu Pro Gly Asp Tyr Leu Leu Ala Gly Leu Phe Pro Leu His Ser
          35                  40                  45            
 Gly Cys Leu Gln Val Arg His Arg Pro Glu Val Thr Leu Cys Asp Arg
      50                  55                  60                
 Ser Cys Ser Phe Asn Glu His Gly Tyr His Leu Phe Gln Ala Met Arg
  65                  70                  75                  80
 Leu Gly Val Glu Glu Ile Asn Asn Ser Thr Ala Leu Leu Pro Asn Ile
                  85                  90                  95    
 Thr Leu Gly Tyr Gln Leu Tyr Asp Val Cys Ser Asp Ser Ala Asn Val
             100                 105                 110        
 Tyr Ala Thr Leu Arg Val Leu Ser Leu Pro Gly Gln His His Ile Glu
         115                 120                 125            
 Leu Gln Gly Asp Leu Leu His Tyr Ser Pro Thr Val Leu Ala Val Ile
     130                 135                 140                
 Gly Pro Asp Ser Thr Asn Arg Ala Ala Thr Thr Ala Ala Leu Leu Ser
 145                 150                 155                 160
 Pro Phe Leu Val Pro Met Ser Cys Phe Gln Ile Pro Ala Ser Thr Leu
                 165                 170                 175    
 Met Gly Lys Pro Ile Leu Leu Gly Asn Tyr Cys His Ser Ala Val Pro
             180                 185                 190        
 Leu Leu Pro Ser Thr Ser Leu Leu Pro Pro Glu Val Pro Leu Pro Leu
         195                 200                 205            
 Leu Gly Met Asp Ile Leu Asp Gly Arg Cys Gly Ser Cys Leu
     210                 215                 220        



      <210> 1483
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1483
 Met Thr Leu Gln Phe Thr Gln Ala Ser Leu His Leu Phe Phe Gln Val
   1               5                  10                  15    
 Val Tyr Ile Leu Glu Lys Lys His Ser Arg Ala Ala Thr Gly Phe Leu
              20                  25                  30        
 Lys Leu Leu Ala Asp Lys Asn Ser Glu Leu Phe Arg Lys Tyr Ala Leu
          35                  40                  45            
 Phe Ser Pro Ser Asp His Arg Val Pro Arg Ile Tyr Val Pro Leu Lys
      50                  55                  60                
 Asp Cys Pro Gln Asp Phe Val Ala Arg Pro Lys Asp Tyr Ala Asn Thr
  65                  70                  75                  80
 Leu Phe Ile Cys Arg Ile Val Asp Trp Lys Glu Asp Cys Asn Phe Ala
                  85                  90                  95    
 Leu Gly
        



      <210> 1484
      <211> 101
      <212> PRT
      <213> Homo sapiens


      <400> 1484
 Met Gly Gly Ile Arg Ala Leu Leu Pro Ser Leu Gly Val Ala Pro Gly
   1               5                  10                  15    
 Cys Cys Leu Gly Gly Leu Leu Met Val Thr Ser Ser Ser Pro Arg Pro
              20                  25                  30        
 Arg Tyr Arg Ile Gln Ser Leu Gly His Leu Asp Thr Glu Leu Ser Ser
          35                  40                  45            
 Tyr Gly Asn Thr Leu Phe Glu Glu Pro Met Lys Gln Cys Gln Ala Gly
      50                  55                  60                
 Thr Arg Ile Ser Ser Asp Phe Phe Glu Glu Glu Ser Leu Phe Leu His
  65                  70                  75                  80
 Ser Gln Ala Met Ser Glu Trp Asn Lys Lys Asn Arg Val Pro Phe Tyr
                  85                  90                  95    
 Glu Ile Leu Ser Ala
             100    



      <210> 1485
      <211> 334
      <212> PRT
      <213> Homo sapiens


      <400> 1485
 Met Leu Leu Leu Val Gly Leu Ile Leu Ala Ile Lys Val Arg Asn Gln
   1               5                  10                  15    
 Asp Ser Ala Gly Ala Ile Asp Lys Pro Gly Leu Ser Ala Thr Trp Lys
              20                  25                  30        
 Glu Thr Gly Gln His Leu Trp Gly Lys Asp Leu His Ile Pro Trp Arg
          35                  40                  45            
 Pro Gly Asn Cys Ala Gln Thr Glu Val Ile Glu Ala Lys Arg Cys Asn
      50                  55                  60                
 Gly Tyr Ser Val Ile Asp Gly Glu Thr Leu Glu Glu Ile Glu Ala Gly
  65                  70                  75                  80
 Lys Leu Ser Lys Asn Trp Thr Ala Gln Thr Cys Glu Leu Phe Ala Leu
                  85                  90                  95    
 Ser Gln Ala Leu Lys Tyr Leu Gln Asn Gln Glu Gly Ala Ile Tyr Thr
             100                 105                 110        
 Asn Ser Lys Tyr Ala Phe Gly Val Ala His Thr Phe Gly Lys Ile Trp
         115                 120                 125            
 Thr Glu Arg Ala Ser Pro Lys Ser Ser Ser Lys Asn Ser His Asn Glu
     130                 135                 140                
 Thr Val Val Pro Pro Pro Ser Asn Glu Lys Thr Lys Val Ala Ile Val
 145                 150                 155                 160
 Lys Val Lys Asp Leu Lys Gln Thr Leu Ala Thr Glu Thr Gly Tyr Gln
                 165                 170                 175    
 Asp Val Asn Ala Trp Leu Glu Trp Ile Lys Tyr Ser Ile Arg Thr Leu
             180                 185                 190        
 Asn Lys Ser Asn Cys Tyr Ala Cys Ala His Ser Arg Pro Glu Ala Gln
         195                 200                 205            
 Ile Val Pro Phe Pro Leu Gly Trp Ser Phe Ser Gln Arg Gly Met Gly
     210                 215                 220                
 Cys Met Val Ala Leu Phe Gln Gly Ser Thr Ala Trp Cys Asn Lys Ser
 225                 230                 235                 240
 Cys Gln Ser Leu Ser Leu Leu Tyr Pro Lys Val Gln His Leu Ala Gly
                 245                 250                 255    
 Gln Pro Pro Arg Thr Ile Gln Leu Pro Ser Pro Asp Thr Lys Phe Thr
             260                 265                 270        
 Ser Cys Leu Ser Gln Gln Gly Gly Asn Leu Ala Leu Leu Gly Asn Leu
         275                 280                 285            
 Lys Asp Ala Val Ser Leu Arg Leu Ser Lys Ser Leu Pro Ile Ser Gln
     290                 295                 300                
 Pro Leu Tyr Asn Pro Glu Gln Ile Tyr Gly Gly Ile Val Val Asp Leu
 305                 310                 315                 320
 Tyr Arg Thr Leu Cys Gln Val Thr Gly Ala Ala Leu Val Leu
                 325                 330                



      <210> 1486
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1486
 Met Ala Trp Gln Arg Ala Leu Leu Gln Leu Ala Gly Pro Ser Phe His
   1               5                  10                  15    
 Ala Val Leu Leu Val Ala Gly Arg Ser Asp Gly Arg Lys Gly Ser Leu
              20                  25                  30        
 Asp Thr Asp Val Ala His Val Trp Leu Pro Pro Asn Ala Leu Ile Leu
          35                  40                  45            
 Glu Gly Pro Asp Ser Phe Gln Met Gly Ala Val Thr Ala Ser Phe Pro
      50                  55                  60                
 Glu Ser Ser Arg Gln Ala Ala Arg Pro Ser Gly Gly Ala Ala Gln Gly
  65                  70                  75                  80
 Leu Ser Leu Pro Leu Gly Glu Val Pro Leu Thr Ser Phe Arg Val Leu
                  85                  90                  95    
 Leu Cys Val Val Arg Ala Leu
             100            



      <210> 1487
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 1487
 Met Ser Val Cys Met Ser Val Ser Gly Pro Leu Ala Leu Ala Cys Ala
   1               5                  10                  15    
 Cys Arg Pro Leu Ser Leu Gly Leu Ser Ser Val Cys Thr Cys Pro Tyr
              20                  25                  30        
 Val Asn Met Pro Gln Asn Ile Asp Leu Gly Asn His Lys Leu Lys Met
          35                  40                  45            
 Glu Ala Pro Gln Met Glu Gly Val Trp Ile Pro Lys Ala Pro Leu Ala
      50                  55                  60                
 Ala Glu Pro Pro Ala Asp Gln Ala Tyr Pro Val Gln Gly Arg Asp Gln
  65                  70                  75                  80
 Gly Gly Lys Glu Tyr Glu Glu Ala Arg Thr Gly Trp Phe Ala Ser Arg
                  85                  90                  95    
 Ser Glu Lys Asn Thr Glu Ser Pro Glu Ile Cys Ile Pro Gln Glu Ser
             100                 105                 110        
 Glu Glu Ala Thr Ala Ser Lys Gln
         115                 120



      <210> 1488
      <211> 400
      <212> PRT
      <213> Homo sapiens


      <400> 1488
 Met Asp Ser Ala Pro Leu Phe Pro Arg Pro His Leu Phe Gln Asn Leu
   1               5                  10                  15    
 Leu Leu Phe Leu Trp Ala Leu Leu Asn Cys Gly Leu Gly Val Ser Ala
              20                  25                  30        
 Gln Asp Cys Pro Pro Gly Ala Val Pro Phe Arg Asp Leu Gln Cys Ala
          35                  40                  45            
 Leu Tyr Asn Gly Arg Pro Val Leu Gly Thr Gln Lys Thr Tyr Gln Trp
      50                  55                  60                
 Val Pro Phe His Gly Ala Pro Asn Gln Cys Asp Leu Asn Cys Leu Ala
  65                  70                  75                  80
 Glu Gly His Ala Phe Tyr His Ser Phe Gly Arg Val Leu Asp Gly Thr
                  85                  90                  95    
 Ala Cys Ser Pro Gly Ala Gln Gly Val Cys Val Ala Gly Arg Cys Leu
             100                 105                 110        
 Ser Ala Gly Cys Asp Gly Leu Leu Gly Ser Gly Ala Leu Glu Asp Arg
         115                 120                 125            
 Cys Gly Arg Cys Gly Gly Ala Asn Asp Ser Cys Leu Phe Val Gln Arg
     130                 135                 140                
 Val Phe Arg Asp Ala Gly Ala Phe Ala Gly Tyr Trp Asn Val Thr Leu
 145                 150                 155                 160
 Ile Pro Glu Gly Ala Arg His Ile Arg Val Glu His Arg Ser Arg Asn
                 165                 170                 175    
 His Leu Gly Ile Leu Gly Ser Leu Met Gly Gly Asp Gly Arg Tyr Val
             180                 185                 190        
 Leu Asn Gly His Trp Val Val Ser Pro Pro Gly Thr Tyr Glu Ala Ala
         195                 200                 205            
 Gly Thr His Val Val Tyr Thr Arg Asp Thr Gly Pro Gln Glu Thr Leu
     210                 215                 220                
 Gln Ala Ala Gly Pro Thr Ser His Asp Leu Leu Leu Gln Val Leu Leu
 225                 230                 235                 240
 Gln Glu Pro Asn Pro Gly Ile Glu Phe Glu Phe Trp Leu Pro Arg Glu
                 245                 250                 255    
 Arg Tyr Ser Pro Phe Gln Ala Arg Val Gln Ala Leu Gly Trp Pro Leu
             260                 265                 270        
 Arg Gln Pro Gln Pro Arg Gly Val Glu Pro Gln Pro Pro Ala Ala Pro
         275                 280                 285            
 Ala Val Thr Pro Ala Gln Thr Pro Thr Leu Ala Pro Val Phe Gln Ala
     290                 295                 300                
 Arg Val Leu Gly His His His Gln Ala Gln Glu Thr Arg Tyr Glu Val
 305                 310                 315                 320
 Arg Ile Gln Leu Val Tyr Lys Asn Arg Ser Pro Leu Arg Ala Arg Glu
                 325                 330                 335    
 Tyr Val Trp Ala Pro Gly His Cys Pro Cys Pro Met Leu Ala Pro His
             340                 345                 350        
 Arg Asp Tyr Leu Met Ala Val Gln Arg Leu Val Ser Pro Asp Gly Thr
         355                 360                 365            
 Gln Asp Gln Leu Leu Leu Pro His Ala Gly Tyr Ala Arg Pro Trp Ser
     370                 375                 380                
 Pro Ala Glu Asp Ser Arg Ile Arg Leu Thr Ala Arg Arg Cys Pro Gly
 385                 390                 395                 400





      <210> 1489
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1489
 Met Lys Leu Ser Tyr Cys Ile Cys Ala Pro Phe Phe Arg Tyr Gln Leu
   1               5                  10                  15    
 Phe Leu Ala Ser Cys Leu Gly Val Gln Leu Ile Met Gly Met Leu Ser
              20                  25                  30        
 Glu Lys Pro Arg Ser Gly Thr Pro Ala Glu Val Ala Ala Cys Glu Arg
          35                  40                  45            
 Val Gln Gln Lys Ala Ala Val Thr Leu Ala Arg Leu Ser Arg Asp Pro
      50                  55                  60                
 Asp Val Ala Arg Glu Ala Val Arg Leu Ser Cys Met Ser Arg Leu Ile
  65                  70                  75                  80
 Glu Leu Cys Arg Ser Pro Ser Glu Arg Asn Ser Ser Asp Ala Val Leu
                  85                  90                  95    
 Val Ala Cys Leu Lys Lys Val Leu Ala Leu Val Phe Lys Glu His Lys
             100                 105                 110        
 Gly Glu Val Met Asp Leu Lys Ile Leu Gln Ala Val Ser Gln
         115                 120                 125    



      <210> 1490
      <211> 237
      <212> PRT
      <213> Homo sapiens


      <400> 1490
 Met Gly Pro Val Pro Leu Val Trp Ala Met Ser Gln Leu Ser Leu Ser
   1               5                  10                  15    
 Ala Lys Met Asp Arg Arg Arg Thr Gly Val Met Met Thr Ser Thr Pro
              20                  25                  30        
 Ile Thr Trp Gly Thr Leu Glu Lys Thr Met Gln Glu Ala Glu Lys Leu
          35                  40                  45            
 Leu Glu Arg Gln Gly Gln Lys Lys Pro Leu Ile Pro Cys Ser Trp Pro
      50                  55                  60                
 Trp Arg Lys Gly Pro Ile Gln Glu Thr Ile Trp Lys Ala Ala Leu Leu
  65                  70                  75                  80
 Phe Thr Asn Gly Ser Ile Arg Val Gly Thr Leu Ser Asn Thr Ser Thr
                  85                  90                  95    
 Ala Thr Gln His Ser Leu Asn Val Thr Phe Val Lys Asn Ile Thr Thr
             100                 105                 110        
 Gln Phe Met Val Cys Gly Phe Asn Pro Tyr Val Phe Leu Ala Ala Lys
         115                 120                 125            
 Ala Asp Gln Leu Gln Val Val Val Ser His Thr Thr Thr Ala Ser Gln
     130                 135                 140                
 Glu Arg Val Arg Ala Gln Gly Cys Leu Leu Pro Pro Gln Cys Gln Cys
 145                 150                 155                 160
 Pro Leu Pro Arg Lys Val Lys Ser Ala Glu Gln Gly Ala Glu Ser Thr
                 165                 170                 175    
 Leu Arg Lys Ala Gly Ser Leu Val Ser Arg Leu Pro Cys Gln Arg Glu
             180                 185                 190        
 Thr Gly Lys Thr Ile Glu Gly Lys Phe Leu Leu Ser Gln Gly Glu Gly
         195                 200                 205            
 Tyr Arg Glu Thr Ala Gln Lys Leu Glu Ser Ser Ile Glu Met Phe Leu
     210                 215                 220                
 Ala Tyr Val Ala Cys Thr Ile Arg Phe Pro Ala Val Leu
 225                 230                 235        



      <210> 1491
      <211> 211
      <212> PRT
      <213> Homo sapiens


      <400> 1491
 Met Leu Thr Phe Lys Val Leu Leu Phe Leu Glu Ser Phe His Pro Ser
   1               5                  10                  15    
 Arg Phe Glu Ala Ile Thr Arg Val Leu Leu Lys Pro Leu Ala Asp Val
              20                  25                  30        
 Arg Gly Pro Leu Met Pro Ser Leu Met Ala Ala Lys Thr Ser His Ser
          35                  40                  45            
 Thr Val Trp Cys Gln Arg Arg Glu Thr Ser Asp Phe Asn Phe Ala Ser
      50                  55                  60                
 Leu Leu Gly Arg Glu Phe Tyr Lys Gln Arg Ser Thr Val Leu Val Pro
  65                  70                  75                  80
 Leu Ala Thr Val Met Gly Ala Gly Ala Ser Val Thr Thr Ala Phe Phe
                  85                  90                  95    
 Pro Met Asn Asn Glu Val Leu Ser Asp Leu Lys Gly Gly Gln Asp Ser
             100                 105                 110        
 Gly Leu Lys Glu Ala Asn Arg Lys Ile Gly Thr Gln Cys Ser Leu Pro
         115                 120                 125            
 Val Ala Lys Tyr Leu Asn Ser Pro Ser Ser Cys Glu Leu Thr Asp Phe
     130                 135                 140                
 His Leu Ile Ile Gln Ser Lys Ile Ser Arg Asn Asn Val Arg Gln Gln
 145                 150                 155                 160
 Leu Ser Arg Arg Ala Gln Gln Arg Tyr Ser Glu Trp Arg Val Gly Leu
                 165                 170                 175    
 Lys Glu Gly Ser Gln Glu Leu Ala Ser Leu Ser Gly Ser Gly Ser Glu
             180                 185                 190        
 Asp Asp Gly Thr Ala Val His Gln Gln Pro Lys Ala Trp Thr Gly Ala
         195                 200                 205            
 Leu Val Glu
     210    



      <210> 1492
      <211> 124
      <212> PRT
      <213> Homo sapiens


      <400> 1492
 Met Leu Phe Pro Pro Arg Trp Thr Gly Ala Ala Gly Ala Gly Ala Trp
   1               5                  10                  15    
 Leu Arg Tyr Arg Gly Cys Leu Leu Leu Cys Arg Ser Pro Thr Leu Ser
              20                  25                  30        
 Leu Ser Ser Leu Arg Pro Asp Gly Pro Ala Gln Ser Ser Arg Val Val
          35                  40                  45            
 Phe Arg Val Ala Ala Arg Arg Lys Asp Gly Pro His Thr Leu Gly Glu
      50                  55                  60                
 Arg Asp Ser Gln Lys His Thr Gln Thr Leu Glu Lys Gly Arg Tyr Lys
  65                  70                  75                  80
 Ser Pro Asp Thr Arg Ala His Thr His Gly Glu Ile His Pro Val Thr
                  85                  90                  95    
 Trp Glu His Thr Tyr Thr Pro Ala Phe Pro Pro Thr Thr Pro Gly His
             100                 105                 110        
 Thr Ser Thr Asp Pro Lys Pro Asn Pro Thr Pro Glu
         115                 120                



      <210> 1493
      <211> 289
      <212> PRT
      <213> Homo sapiens


      <400> 1493
 Met Leu Phe Ala Ala Ile Leu Leu Ser Arg Trp Asp Val Thr Ser Ser
   1               5                  10                  15    
 Leu Val Leu Gln Leu Gly Arg His Leu Thr Ser Ile Cys Glu Ser Ala
              20                  25                  30        
 Gly Ser Leu Glu Ser Arg Pro Cys Ser Ser Cys Ser Gly Asp Lys Leu
          35                  40                  45            
 Cys Ile Pro Ser Ser Glu Pro Glu Ala Gly His Pro Gly Pro Ser Pro
      50                  55                  60                
 Gly Ala Pro Tyr Lys Gly Val Gly Glu Ser Ala Pro Leu Pro Arg Phe
  65                  70                  75                  80
 Leu Phe Pro Trp Leu Pro Asn Arg Arg Gly Met Thr Ala Asp Glu Ser
                  85                  90                  95    
 Val Cys Val Ala Ala Thr Gln Thr Val Ser Asn Ile Pro Pro Ala Ser
             100                 105                 110        
 Arg Pro Gly Leu Ser Leu Gln Arg Pro Asn Leu Leu Thr Asp Ala Pro
         115                 120                 125            
 Leu Pro Arg Ser Ala Ser Ile Trp Ser Asn Cys Gln Val Asp Ser Asn
     130                 135                 140                
 Cys Cys Ser Ala Ala Pro Lys Arg Thr Val Ala Asn Thr Asp Ile Val
 145                 150                 155                 160
 Arg Leu Ser Trp Val Cys Leu Tyr Gln Glu Cys Glu Asn Gly Pro Asn
                 165                 170                 175    
 Thr Val Asn Trp Tyr Gln Lys Trp Gly Val Ala Glu Asn Ile Pro Glu
             180                 185                 190        
 Asn Val Lys Ala Thr Leu Glu Leu Gly Asn Gly Pro Thr Leu Glu Gln
         195                 200                 205            
 Phe Gly Gly Leu Arg Arg Arg Gln Glu Asn Val Arg Val Phe Ser Tyr
     210                 215                 220                
 Gln Asn Gln Ser Ile Lys Phe Gly Lys Arg Met His Ala Ser Asn Ala
 225                 230                 235                 240
 Thr Phe Val Arg Leu Cys Lys Ala Thr Arg Ile Met Lys Asn Gln Arg
                 245                 250                 255    
 Asn Met Lys Pro Lys Glu His Asn Lys Leu Leu Ile Ser Asp Leu Lys
             260                 265                 270        
 Glu Leu Asp Ile Val Tyr Gly His Thr Thr Leu Asn Met Pro Asn Pro
         275                 280                 285            
 Val
    



      <210> 1494
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1494
 Met Gly Leu Leu Ile Trp Gly Tyr Leu Tyr Leu Trp Val Glu Thr Leu
   1               5                  10                  15    
 Thr Thr Cys Gly Gly Asn Pro Thr Ala Leu Glu Pro Lys Glu Ser Asn
              20                  25                  30        
 Gly Cys Asn Lys Cys Thr Gly Leu Ser Ala Leu Arg Gln Gly Asn Arg
          35                  40                  45            
 Gly Gln Arg Gly Pro Ser Lys Lys Ser Trp Met Trp Pro Ile Pro Ser
      50                  55                  60                
 Pro Ser Cys Phe Leu Glu Met Arg Lys Ser Arg Lys Gly His Arg Gly
  65                  70                  75                  80
 Phe Arg Asn Asp Arg Gly Asp Asp Ser Phe Asp Val Trp Ser Ser Ser
                  85                  90                  95    
 Arg Pro Leu Pro Thr Pro Lys Arg Lys Leu Asp
             100                 105        



      <210> 1495
      <211> 141
      <212> PRT
      <213> Homo sapiens


      <400> 1495
 Met His Ser Gly Ala Trp His Asn Ser Ile Ser His Tyr Val Ala Val
   1               5                  10                  15    
 Leu Leu Leu Cys Leu Phe Pro His Leu Glu Thr Glu His Asn Ser Ala
              20                  25                  30        
 Ser Val Asp Ser Ile Ser Gly His Val Leu Gln Gln Asp Ala Thr Asp
          35                  40                  45            
 Gln Asn Leu Ala Lys Cys Glu Val His Gln Pro Arg Met Leu Thr Ala
      50                  55                  60                
 Ser Val Pro His Pro Ser Leu Val Ala Cys Asp Pro Gln Lys Asn Gly
  65                  70                  75                  80
 Lys Asp Phe Leu Val Ser Pro Trp Gly Leu Gln Gly Gly Gly Gly Lys
                  85                  90                  95    
 Ala Arg Gln Leu Gln Leu Ser Gly Ser Arg Gly Arg Arg Trp Ala Arg
             100                 105                 110        
 Arg Pro Pro Ser Glu Val Val Ala Ala Cys Glu Ser Pro Arg Arg Gly
         115                 120                 125            
 Gly Ser Ser Phe Gln Ile Glu Ala Lys Arg Pro Val Thr
     130                 135                 140    



      <210> 1496
      <211> 280
      <212> PRT
      <213> Homo sapiens


      <400> 1496
 Met Arg Asp Gly Pro Ile Leu Pro Ala Tyr Ile Phe Leu Leu Ser Trp
   1               5                  10                  15    
 Met Leu Pro Ala Leu Glu His Arg Thr Pro Ser Ser Ser Val Leu Arg
              20                  25                  30        
 Leu Gly Leu Ala Leu Leu Ala Pro Gln Leu Ala Asp Ser Leu Leu Trp
          35                  40                  45            
 Asp Leu Val Ile Val Pro Ile Thr Lys Leu Lys Ser Gln Gln Ala Pro
      50                  55                  60                
 Gly Gly Glu Val Glu Ser Val Thr Tyr Glu Glu Val Gln Tyr Thr Gln
  65                  70                  75                  80
 Lys Glu Leu Phe Glu Phe Pro Asn Leu Tyr Lys Gln Gln Ser Gly Glu
                  85                  90                  95    
 Gln Ala Trp Glu Trp Ile Leu Arg Val Trp Asp Asn Gly Gly Arg Asn
             100                 105                 110        
 Ile Glu Leu Asp Gln Phe Glu Phe Ile Asp Leu Asp Asn Gln Ser Cys
         115                 120                 125            
 His Gly Gly Arg Asp Gly Gly Tyr Ala Trp Ala Gln Glu His Gly Leu
     130                 135                 140                
 Pro Leu Thr Lys Ala Asp Leu Ala Met Ala Thr Ala Glu Cys Pro Ile
 145                 150                 155                 160
 Phe Gln Gln Gln Arg Pro Thr Leu Ser Thr Gln Tyr Gly Thr Ile Pro
                 165                 170                 175    
 Arg Gly Asp Gln Pro Ala Thr Trp Trp Gln Val Asn Tyr Ile Gly Pro
             180                 185                 190        
 Leu Pro Ser Trp Lys Trp Arg Arg Phe Val Leu Thr Gly Ile Asp Thr
         195                 200                 205            
 Tyr Ser Gly Tyr Ser Leu Pro Ile Leu His Ala Met Leu Leu Pro Arg
     210                 215                 220                
 Leu Pro Ser Met Asp Ser Arg Asn Ala Ser Ser Thr Ile Ile Val Phe
 225                 230                 235                 240
 His Thr Ala Leu Pro Leu Thr Lys Ala Leu Thr Leu Gln Leu Lys Lys
                 245                 250                 255    
 Cys Gly Ser Gly Leu Met Leu Met Glu Phe Thr Gly Leu Asn Met Phe
             260                 265                 270        
 Pro Ile Val Leu Lys Gln Leu Asp
         275                 280



      <210> 1497
      <211> 116
      <212> PRT
      <213> Homo sapiens


      <400> 1497
 Met Asp Thr Leu Val Leu Val Ser Val Ile Leu Ile Thr Arg Arg Gly
   1               5                  10                  15    
 Pro Ala His Leu Gly Ala His Cys Gly Gly Gly Leu Val Leu Met Gln
              20                  25                  30        
 Val Leu Met Glu Leu Leu Glu Leu Ala Val Ala Phe Ala Glu Gln Glu
          35                  40                  45            
 Gln Leu Cys Leu Trp Phe Leu Arg Ile Glu Lys Pro Pro Pro Ala Ser
      50                  55                  60                
 Lys Val Leu Glu Asp Thr Val Gly Arg His Gln Arg Ala Phe Ser Asp
  65                  70                  75                  80
 His Leu Phe Ser Arg Lys Tyr Ser Trp Glu Val Gln Asn Asn Ser Pro
                  85                  90                  95    
 Leu Arg Pro Val Leu Asp Glu Met Val Val Ser Asn Thr His Ser Glu
             100                 105                 110        
 Thr Leu Gly Val
         115    



      <210> 1498
      <211> 311
      <212> PRT
      <213> Homo sapiens


      <400> 1498
 Met Asp Leu Ala His Leu Cys Leu Val Phe His Tyr Gln Asn Thr Lys
   1               5                  10                  15    
 His Val Gly Val Ile Tyr Ile Leu Leu Leu Lys Val Ile Val Ile Ala
              20                  25                  30        
 Lys Leu Leu Glu Ala Gly Thr Ala Ala Val Ala Ile Leu Thr Val Leu
          35                  40                  45            
 His Asn Leu Ser Leu Thr Ala Leu Ser Leu Glu Glu Gly Gly Gly Asp
      50                  55                  60                
 His Gln Gln Gly Lys His Arg Pro Pro Val Leu Leu Asn Leu Arg Cys
  65                  70                  75                  80
 Ser Arg Val Cys Val Asp Pro Leu Arg Thr His Gln Gly Leu Cys Asp
                  85                  90                  95    
 Phe Leu Val Ala Ala Glu Ala Leu Arg Lys Arg Arg Arg Trp Leu Cys
             100                 105                 110        
 Val Trp Ala His Arg Ala Arg Pro Ala His Val His Ala Pro Ala Gly
         115                 120                 125            
 Pro Ala Ala Leu Thr Tyr Thr Leu Pro Gln Gly Pro Pro Pro Leu Arg
     130                 135                 140                
 Thr Arg Ser Arg Arg Ala His His Pro Arg Val His Ala Pro Ala Gly
 145                 150                 155                 160
 Pro Ala Thr Leu Thr Tyr Thr Leu Pro Gln Gly Pro Pro Arg Ser Arg
                 165                 170                 175    
 His Val His Gly Arg His Gly Ala Pro Arg Cys Pro Glu Ser Pro Ala
             180                 185                 190        
 Arg Thr Pro Arg Cys Pro Ser Leu Ser Arg Val Thr Cys Thr Asp Ala
         195                 200                 205            
 Thr Val Pro Leu Ala Val Pro Ser His Leu His Asp Ala Thr Val Pro
     210                 215                 220                
 Leu Ala Val Leu Gly His Leu His Asp Ala Thr Val Pro Leu Ala Val
 225                 230                 235                 240
 Leu Ile His Leu His Ala Ser Pro Val Ser Ser Leu His Arg Asp Tyr
                 245                 250                 255    
 Asp Gly Thr Phe Pro Ile His Val Ala Cys Leu Ser Leu Glu Pro Thr
             260                 265                 270        
 Ala Leu Ala Thr Arg Gly Phe Val Met Gly Val Phe Cys Glu Glu Asp
         275                 280                 285            
 Val Asn Phe Leu Pro Val Leu Thr Pro Ser Ser Val Lys Gly Asp Leu
     290                 295                 300                
 Leu Gln Ala Gly Gly Ser Gly
 305                 310    



      <210> 1499
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 1499
 Met Ala Pro Ala Leu Trp Arg Ala Cys Asn Gly Leu Met Ala Ala Phe
   1               5                  10                  15    
 Phe Ala Leu Ala Ala Leu Val Gln Val Val Tyr Thr Ile Pro Ala Val
              20                  25                  30        
 Leu Thr Leu Leu Val Gly Leu Asn Pro Glu Val Thr Ala Met Lys Ser
          35                  40                  45            
 Asp Phe Tyr Leu Arg Tyr Tyr Val Gly His Lys Gly Lys Phe Ser His
      50                  55                  60                
 Glu Phe Leu Glu Phe Glu Phe
  65                  70    



      <210> 1500
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1500
 Met Phe Leu Val Leu Met Arg Thr Val Cys Ile Leu Trp Gln Leu Asp
   1               5                  10                  15    
 Glu Val Phe Tyr Ser Ser Ser Arg Ile Ser Glu Ser Ile Lys Ala Val
              20                  25                  30        
 Asp Leu Ser Glu Lys Cys Val Glu Glu Ile Met Met Trp Thr Phe Asn
          35                  40                  45            
 Pro Ala Val Leu Thr Lys Ala Asn Ile Val Arg Ser Gly Asp Ala Ala
      50                  55                  60                
 Gln Gly Ala Glu Gly Gly Thr Ser Gln Phe Gln Val Gly Asp Leu Val
  65                  70                  75                  80
 Gln Val Cys Tyr Asp Leu Glu Arg Ile Lys Leu Leu Gln Arg Gly His
                  85                  90                  95    
 Gly Glu Trp Ala Glu Ala Met Leu Pro
             100                 105



      <210> 1501
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1501
 Met Leu Ala Met Leu Ala Leu Lys Thr Gly Val Met Trp Pro Gln Ala
   1               5                  10                  15    
 Lys Glu His Gln Trp Pro Pro Glu Ala Gly Arg Glu Asp Lys Glu Asn
              20                  25                  30        
 Ala Leu Leu Pro Glu Gln Pro Ser Cys Tyr Tyr Ser Ile Gln Phe Pro
          35                  40                  45            
 Asp Gly Lys Gly Ile Leu Ser Arg Trp Arg Leu Ile Leu Pro Lys Gln
      50                  55                  60                
 Ile Gly Asn Phe Gln Ser Cys Cys Gln Tyr Gly Ser Ala Val
  65                  70                  75            



      <210> 1502
      <211> 210
      <212> PRT
      <213> Homo sapiens


      <400> 1502
 Met Leu Ala Ser Val Glu Glu Arg Ser Leu Ser Ile Pro Gly Ile Trp
   1               5                  10                  15    
 Gly Ser Gly Lys Ser Glu Ala Leu Trp Leu Trp Pro Arg Lys Met Leu
              20                  25                  30        
 Glu Ala Trp Trp Gly Val Leu Cys Val His Cys Pro Thr Cys Leu Gly
          35                  40                  45            
 Ala Leu Ala Ser Pro Pro Met Leu Arg Leu Ala Val Pro Leu Pro Gln
      50                  55                  60                
 Ala Ser Lys Val Trp Ser Glu Ser Ile Lys Asp Thr Glu Ala Gly Leu
  65                  70                  75                  80
 Pro Leu Ala Ser Leu Trp Thr Thr Gly Gly Leu Leu Pro Met Gln Phe
                  85                  90                  95    
 Glu Ser Ala Asn Ile Asp Gln Gly Leu Leu Cys Ala Arg Pro Arg Gly
             100                 105                 110        
 Arg Ala Pro Gly Pro Glu Val His Gly Gln His Trp Met Gly Phe Trp
         115                 120                 125            
 Val Pro His Arg Ala Glu Ala Glu Lys Asp Arg Ala Leu Ala Met Pro
     130                 135                 140                
 Thr Gly Ile Phe Leu Ala Leu Pro Pro Pro Arg Asp Val Val Gln Glu
 145                 150                 155                 160
 His Trp Leu Leu Gly Gly Pro Ile Leu Pro Glu Leu Gly Val Phe Cys
                 165                 170                 175    
 Lys Pro Val Gln Ser Gly Glu Gly Leu Gly Gly Leu Leu Thr Val Thr
             180                 185                 190        
 Ser Ala Ala Gly Gly Gln Ser Gly Ala Ser Ser Thr Cys Ser Val Leu
         195                 200                 205            
 Gly Leu
     210



      <210> 1503
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 1503
 Met Leu Leu Phe Pro Ile Pro Asp Val Val Met Val Val Trp Leu Cys
   1               5                  10                  15    
 Phe Ile Gln Met Thr Cys Glu Thr Asn Pro Ala Leu Thr Ala Gly Ile
              20                  25                  30        
 Val Thr Phe Met Phe Ser Phe Pro Gly Tyr Ile Ser Phe Gln Leu Arg
          35                  40                  45            
 Ser Leu Glu Lys Cys Leu Cys Lys Glu Gln Arg Arg Asn Glu Gly Asp
      50                  55                  60                
 Leu Phe His Arg Leu Trp His Ile Met Asn Glu Ile Leu Asp Leu Arg
  65                  70                  75                  80
 Arg Gln Val Leu Val Gly His Leu Thr His Asp Arg Met Lys Asp Val
                  85                  90                  95    
 Lys Arg His Ile Thr Ala Arg Leu Asp Trp Gly Asn Glu Gln Leu Gly
             100                 105                 110        
 Leu Asp Leu Val Pro Arg Lys Glu Tyr Ala Met Val Asp Pro Glu Asp
         115                 120                 125            
 Ile Ser Ile Thr Glu Leu Tyr Arg Leu Val Glu Ser Arg Ala Leu Ile
     130                 135                 140                
 Gln Asn Lys Trp Asn Ala Tyr Gln Met Glu Asp Leu Lys Ala Glu Leu
 145                 150                 155                 160
 Glu Asn Gly Thr Gln Asp Leu Val Thr Ala Lys Ser Gln Leu Ser Val
                 165                 170                 175    
 His Arg Lys Arg Glu Glu Thr Lys Leu Met Glu Pro Lys Tyr Pro Pro
             180                 185                 190        
 Arg Arg Glu Glu Val Ile Glu Glu Tyr Trp Tyr Pro Ala Ser Ser His
         195                 200                 205            
 Gln Ile Lys Asp Phe
     210            



      <210> 1504
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1504
 Met Ser Val Leu Ser Phe Pro Ile Thr Val Phe Ser Tyr Ala Trp Ser
   1               5                  10                  15    
 Ser Leu Pro Phe Met Thr Phe Glu Lys Ile Ser Gly Arg Ser Gln Asn
              20                  25                  30        
 Phe Lys Val Gln Phe Glu Ser Leu Val Arg Tyr Asp Leu Ser Glu Cys
          35                  40                  45            
 Leu Leu Cys Gly Leu Leu Asp Asp Thr Asp Asn Ile His Tyr Asn Asn
      50                  55                  60                
 Lys Leu His Lys Leu Lys Leu Lys Thr Cys Glu Tyr Ala Lys Glu Thr
  65                  70                  75                  80
 Asn Tyr Ile Ser Leu Gly Glu Ser Ser Val Asn Gln Ala Lys Gly Leu
                  85                  90                  95    
 Glu Ala Lys Cys Arg Leu Arg Gly Gly Val Lys
             100                 105        



      <210> 1505
      <211> 161
      <212> PRT
      <213> Homo sapiens


      <400> 1505
 Met Gly Gly Val Ala Gln Val Arg Trp Leu Leu Trp Gln Leu Arg Leu
   1               5                  10                  15    
 Pro Leu Arg Ala Ala Ala Pro Arg Pro Pro Ser Asp Asn Gln Leu Leu
              20                  25                  30        
 Lys Leu Pro Phe Pro Gly Ile Cys Pro Asp Trp Ile Ile Asn Tyr Val
          35                  40                  45            
 Ile Asn Leu Leu Pro Thr Leu Lys Asp Met Ile Leu Tyr Ser Pro Leu
      50                  55                  60                
 Val Ser Arg Ser Ser Ser Asn Ser Phe Asn Glu Phe Leu Tyr Leu Arg
  65                  70                  75                  80
 Gly Arg Leu Gln Arg Gln Gly Phe Val Pro Gly Ser Pro Gly Asn Lys
                  85                  90                  95    
 Asp Leu Phe Tyr Thr Leu Glu Gln Ile Asp Gln Val Val Asp Leu Arg
             100                 105                 110        
 His Leu Thr Ser Glu Gly Phe Gln Glu Met Pro Leu Gln Asn Met Leu
         115                 120                 125            
 Leu Trp Tyr Thr Asp Tyr Phe Gln Leu Lys Ala Leu Lys Asp Gln Gln
     130                 135                 140                
 Met Gln Gly Gly Gly Glu Thr Cys Gly Thr Asp Val Asp Gln Pro Pro
 145                 150                 155                 160
 Asp
    



      <210> 1506
      <211> 424
      <212> PRT
      <213> Homo sapiens


      <400> 1506
 Met His Leu Val Ser Phe Gly Ser Pro Asp Glu Gln Phe Glu Ile Ala
   1               5                  10                  15    
 Val Ile Leu Ser His Arg Tyr Ser Gln Phe Leu Leu Leu Thr Val Val
              20                  25                  30        
 Ile Phe Tyr Lys Val Gly His Val Thr Gly Val Trp Leu Ala Cys Asn
          35                  40                  45            
 Arg Ser Pro Leu Leu Leu Leu Leu Leu Leu Lys Pro Leu Ala Gly Gly
      50                  55                  60                
 Gly Ala Gln Arg Gln Ala Asp Ala Gly Ala Arg Gly Lys Tyr Val Trp
  65                  70                  75                  80
 Lys Glu Ile Lys Val Met Asn Lys Gly Ser Val Ser Leu Ala Ile His
                  85                  90                  95    
 Ser Cys Ala Phe Val Ile Glu Gln Glu Glu Lys Lys Lys Thr Glu Ala
             100                 105                 110        
 His Lys Glu Gly Asp Gly Val Lys Arg Ala Asp Lys Ile Leu Gly Val
         115                 120                 125            
 Thr Lys Asp Pro Gly Thr Ile Ala Gly Leu Asn Val Val Arg Ile Ile
     130                 135                 140                
 Asn Glu Pro Thr Ala Ala Ser Ile Ala Tyr Gly Thr Asp Lys Lys Phe
 145                 150                 155                 160
 Gly Ala Glu Arg His Val Leu Ile Tyr Asp Leu Arg Asp Glu Ile Phe
                 165                 170                 175    
 Asp Val Ser Val Leu Thr Leu Glu Asp Glu Ile Phe Glu Ile Lys Ser
             180                 185                 190        
 Thr Ala Gly Asp Thr His Leu Gly Glu Glu Asp Phe Asp Asn Gln Met
         195                 200                 205            
 Ile Asn His Phe Ile Ala Glu Phe Lys Tyr Lys His Lys Asp Ser Arg
     210                 215                 220                
 Ala Asp Ile Tyr Thr Ser Ile Thr His Ala Gln Phe Glu Glu Leu Asn
 225                 230                 235                 240
 Ala Val Leu Phe Arg Gly Thr Gln Asp Pro Ile Glu Ile Ala Leu Gln
                 245                 250                 255    
 Asp Thr Lys Leu Asp Lys Leu Gln Ile His Val Ile Val Leu Thr Gln
             260                 265                 270        
 Thr Phe Thr Thr Tyr Pro Asp Asn Gln Pro Asp Val Leu Ile Gln Val
         275                 280                 285            
 Tyr Glu Gly Glu Ser Ala Ile Thr Lys Asp Asn Asn Leu Leu Val Ile
     290                 295                 300                
 Gln Gly Lys Phe Glu Leu Thr Gly Ile Leu Pro Ala Pro Phe Ala Val
 305                 310                 315                 320
 Pro Gln Ile Lys Val Thr Cys Asp Ile Asp Val Asn Ser Ser Leu Asn
                 325                 330                 335    
 Ile Ser Ala Val Gly Lys Ser Thr Glu Lys Glu Asn Lys Ile Ile Ile
             340                 345                 350        
 Thr Asn Asp Gln Gly His Leu Ser Lys Glu Asp Ile Glu Asn Met Val
         355                 360                 365            
 Gln Glu Ala Glu Tyr Lys Ala Glu Asp Glu Lys Gln Lys Asn Lys Val
     370                 375                 380                
 Ala Ser Lys Asn Ser Leu Asp Ser Tyr Ala Phe Asn Met Lys Ala Thr
 385                 390                 395                 400
 Glu Lys Leu Gln Gly Lys Ile Asn Asn Lys Asp Lys Gln Lys Ile Leu
                 405                 410                 415    
 Asp Lys Cys Asn Lys Ile Ile Asn
             420                



      <210> 1507
      <211> 84
      <212> PRT
      <213> Homo sapiens


      <400> 1507
 Met Lys Met Met Ile Met Met Gly Ile Val Val Leu Met Gly Val Ala
   1               5                  10                  15    
 Cys Ser Ala Ile Leu Met Tyr Ile Phe Cys Thr Asp Cys Trp Leu Ile
              20                  25                  30        
 Ala Val Leu Tyr Phe Thr Trp Leu Val Phe Asp Trp Asn Thr Pro Lys
          35                  40                  45            
 Lys Glu Ile Gln Asn Val Cys Asn Glu Lys Gly Lys Gly Pro Leu Tyr
      50                  55                  60                
 Ile Ser Gln Val Val Leu Asn Pro Pro Gly Thr Met Met Met Arg Ile
  65                  70                  75                  80
 Val Ala Ile Tyr
                



      <210> 1508
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1508
 Met Lys Ser Gly Ala Glu Pro Lys Pro Val Pro Ser Ser Pro Cys Leu
   1               5                  10                  15    
 Arg Ser Phe Leu Leu Leu Thr Trp Arg Gly Ala Pro Ala Leu Pro Ala
              20                  25                  30        
 Arg Trp Cys Arg Gly Pro Ser Arg Leu Gln Gln Trp Gly Thr Gly Thr
          35                  40                  45            
 Ser Trp Thr Lys Asp Glu Asp Ala Ser Ser Met Cys Glu Gln Lys Ala
      50                  55                  60                
 Ala Cys Val Arg Ser Ala Glu Gln Pro Ala Arg Phe His Lys Gly Pro
  65                  70                  75                  80
 Pro Ala Gly Asp Cys His Gly Ala Pro Ser Tyr Pro Phe Trp His Gln
                  85                  90                  95    
 Gln Leu His Pro Gln Ala His Ser Gly
             100                 105



      <210> 1509
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 1509
 Met Ala Ile His Trp Leu Ala Leu Tyr Phe Gly Thr Ile Val Ile Val
   1               5                  10                  15    
 Pro Asn Gly Ser Gln Met Ser Lys Thr Leu Arg Asn Asn Ser Glu Ser
              20                  25                  30        
 Leu Ala Gly Lys Pro His Leu Asn Ala Ala His Thr Phe Met Ile His
          35                  40                  45            
 Tyr Lys Gly Phe Lys Gly Lys Ala Asn Ala Asp Leu Gln Leu Gly Leu
      50                  55                  60                
 Lys
  65



      <210> 1510
      <211> 171
      <212> PRT
      <213> Homo sapiens


      <400> 1510
 Met Gly Leu Arg Pro Thr Cys Ile Thr His Cys Ile Phe Val Leu Ile
   1               5                  10                  15    
 Leu Cys Ser Val Val Lys Asp Ile Val Glu Asn Val Lys Lys Ala Met
              20                  25                  30        
 Asn Asn Ser Asp Arg Lys Lys Gly Lys His Leu Cys Phe Ser Ile Ala
          35                  40                  45            
 Leu Lys Val Arg Leu Leu Glu Lys Leu Asn Ser Ser Val Ser Met Glu
      50                  55                  60                
 His Val Thr Glu Asp Tyr Gly Val Thr Met Thr Thr Ile Tyr Asp Leu
  65                  70                  75                  80
 Lys Asn Lys Asp Lys Leu Leu Lys Phe His Ala Glu Asn Leu Tyr Ser
                  85                  90                  95    
 Glu Lys Ala Ser Ala Asp His Glu Gly Ala Glu Gln Phe Thr Asp Glu
             100                 105                 110        
 Phe Ala Lys Val Ile Ala Asp Gly Asn Leu Met Pro Glu Gln Val Tyr
         115                 120                 125            
 Asn Ala Val Lys Thr Ser Leu Phe Trp Cys Met Val Pro Glu Arg His
     130                 135                 140                
 Trp Pro Gln Leu Met Arg Gln Leu Leu Gln Glu Leu Arg Met Pro Lys
 145                 150                 155                 160
 Thr Glu Gln Leu Cys Trp Asp Val Leu Met Gln
                 165                 170    



      <210> 1511
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1511
 Met Ala Ala Leu Ser Arg Ala Leu Gly Pro Leu Arg Thr Pro Ala Pro
   1               5                  10                  15    
 Pro Leu Trp Ile Gly Leu Phe Leu Val Ala Thr Gly Ser Gln Gln Ser
              20                  25                  30        
 Leu Ala Gln Pro Leu Pro Gly Asn Thr Thr Glu Ala Thr Pro Arg Ser
          35                  40                  45            
 Leu Arg Ala Ser Gly Ser Leu Cys Gly Pro His Ala Lys Ala Pro Tyr
      50                  55                  60                
 Leu Cys Glu Ala Thr His Glu Pro Ala Ala Ala Arg Ile Arg Ala Gln
  65                  70                  75                  80
 Val Pro Asp Thr Arg Trp Ser Arg Val Gly Gly Gln Arg Phe Tyr Ser
                  85                  90                  95    
 Arg Val Leu Ser Pro Leu His Arg Gly Pro Ser Gly His Thr Glu Ala
             100                 105                 110        
 Ser Ala Gln Arg Ser His Met Gly Lys Leu Lys Glu Pro Gln Pro Gln
         115                 120                 125            
 Asp His Lys Pro Gly Leu Gly Ala Ser
     130                 135        



      <210> 1512
      <211> 183
      <212> PRT
      <213> Homo sapiens


      <400> 1512
 Met Ser Leu Gly Leu Gly Ala Leu Ala Ala Thr Gln Ala Ala Leu Thr
   1               5                  10                  15    
 Thr Leu Arg Leu Cys Pro Cys Lys Phe Asp Ser Tyr Pro Tyr Gln Trp
              20                  25                  30        
 Ala Pro Glu Gly Leu Pro Met Pro His Leu Pro Lys Val Leu Cys Arg
          35                  40                  45            
 Asn Gly Asn Gly Val Glu Gly Ser Arg Glu Glu Ser Leu Leu Thr Val
      50                  55                  60                
 Leu Arg Gly Arg Gln Gly Asn Gly Gly Ala Gly Thr Ile Tyr Val Thr
  65                  70                  75                  80
 Val Thr Leu Val Lys Ile Asn Gly Glu Lys Tyr Ala Leu Pro Ala Gly
                  85                  90                  95    
 Gly Thr Gln Lys Val Pro Trp Ser Ser Thr Ala Cys Val Ser Glu Trp
             100                 105                 110        
 Thr Gly Lys Lys Leu Tyr Leu Leu Pro Val Lys Gly Gly Lys Tyr Leu
         115                 120                 125            
 Val Glu Asp Asn Phe Asn Tyr Gly Leu Tyr Val Arg Thr Ser Leu Tyr
     130                 135                 140                
 Leu Gln Pro Leu Pro Phe Ser Trp Ile Pro Gly Leu His Ser Ser Phe
 145                 150                 155                 160
 Gln Pro Asp Asn Cys Ser Gln Cys Pro Trp Pro Pro Gln Arg His Pro
                 165                 170                 175    
 Val Tyr Ser Lys His Leu Leu
             180            



      <210> 1513
      <211> 308
      <212> PRT
      <213> Homo sapiens


      <400> 1513
 Met Leu Gly Thr Leu Leu Trp Met Arg Gly Leu Pro Leu Glu Gly Ala
   1               5                  10                  15    
 Ala Glu Asp Trp Gln Leu Gln Met Leu Glu Gln Ala Ser Leu Trp Leu
              20                  25                  30        
 Gly Arg Ser Phe Leu Leu Ala Gly Phe Leu Val Ser Ser Ser Cys Pro
          35                  40                  45            
 Ser Leu Glu Gln Ala Ala Lys Gly Glu Gly Cys Ser Pro Ile Pro Cys
      50                  55                  60                
 Phe Ala His Cys Leu Asp Ser Leu Met Val Val Arg Glu Ala Ser Ala
  65                  70                  75                  80
 Ala Gln Ala Ser Leu Ser Gln Val Leu Pro Gln Leu Arg Tyr Leu His
                  85                  90                  95    
 Ile Phe Leu Glu Gln Val His Thr His Phe Gln Glu Gln Ser Val Gly
             100                 105                 110        
 Glu Arg Gly Ala Ala Ile Gln Leu Ala Glu Gly Leu Ala Arg Gln Leu
         115                 120                 125            
 Cys Thr Asp Cys Gln Leu Asn Lys Leu Phe Tyr Arg Glu Glu Phe Val
     130                 135                 140                
 Leu Ala Thr Leu Leu Asp Pro Cys Phe Lys Gly Lys Ile Glu Ala Ile
 145                 150                 155                 160
 Leu Pro Trp Gly Pro Thr Asp Ile Asp His Trp Lys Gln Val Leu Val
                 165                 170                 175    
 Tyr Lys Val Lys Glu Ile Arg Val Ser Glu Tyr Ser Leu Asn Ser Pro
             180                 185                 190        
 Ser Pro Leu Gln Ser Pro Arg Gly Leu Cys Val Asp Pro Thr Arg Val
         195                 200                 205            
 Ala Lys Ser Ser Gly Val Glu Gly Arg Ser Gln Gly Glu Pro Leu Gln
     210                 215                 220                
 Ser Ser Ser His Ser Gly Ala Phe Leu Leu Ala Gln Arg Glu Lys Gly
 225                 230                 235                 240
 Leu Leu Glu Ser Met Gly Leu Leu Ala Ser Glu Arg Ser Gly Gly Ser
                 245                 250                 255    
 Leu Ser Thr Lys Ser His Trp Ala Ser Ile Ile Val Lys Lys Tyr Leu
             260                 265                 270        
 Trp Glu Asn Glu Thr Val Gly Ala Gln Asp Asp Pro Leu Ala Tyr Trp
         275                 280                 285            
 Glu Lys Lys Arg Glu Ala Trp Pro Pro Ser Ile Cys Leu Thr Pro His
     290                 295                 300                
 Arg Ser Leu Leu
 305            



      <210> 1514
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 1514
 Met Lys Trp Lys Ala Leu Phe Thr Ala Ala Ile Leu Gln Ala Gln Leu
   1               5                  10                  15    
 Pro Ile Thr Gly Gly His Leu Ala Gln Pro Glu Gly Pro Ala Leu Thr
              20                  25                  30        
 Glu His Gly Ala Asp Glu Thr Met Cys Leu Val Lys Ser Pro Pro Arg
          35                  40                  45            
 Ala Ala Pro Ser Gln Gln Glu Cys Leu Leu Leu Thr Ser Phe Pro Ile
      50                  55                  60                
 Val Gly Ala Gln Leu Cys Cys Lys Pro Leu Ala Ser Thr Met Phe Ser
  65                  70                  75                  80
 Ser Pro Ala Gln Lys Arg Gly Thr Val Arg Gln Ser Ala Thr Gln Arg
                  85                  90                  95    
 Gly Leu Asp Thr Glu Gly Cys Asp Gly Ala Phe Ala Ala
             100                 105                



      <210> 1515
      <211> 242
      <212> PRT
      <213> Homo sapiens


      <400> 1515
 Met Phe Leu Leu Pro Ala Val Cys Ser Val Leu Gly Ala Gly Asp Ser
   1               5                  10                  15    
 Ala Val Lys Glu Pro Val Cys Pro His Gly Ala Asn Ser Val Trp Gly
              20                  25                  30        
 Lys Thr Ala Asn Ala Gln Ala Ala Ile Cys Cys Arg Val Val Met Thr
          35                  40                  45            
 Ile Gly Thr Ser Ala Arg Cys Arg Arg Ala Val Ser Ser Thr Glu Leu
      50                  55                  60                
 Ser Ala Leu Glu Asn Ile Cys Lys Ala Ile Ile Lys Glu Lys Gln Pro
  65                  70                  75                  80
 Phe Glu Arg Leu Glu Val Ser Lys Glu Ile Leu Leu Glu Met Phe Lys
                  85                  90                  95    
 Tyr Asn Lys Phe Lys Cys Arg Ile Leu Asn Glu Lys Val Asn Thr Ala
             100                 105                 110        
 Thr Thr Thr Val Tyr Arg Cys Gly Pro Leu Ile Asp Leu Cys Lys Gly
         115                 120                 125            
 Pro His Val Arg His Thr Gly Lys Ile Lys Thr Ile Lys Ile Phe Lys
     130                 135                 140                
 Asn Ser Ser Thr Tyr Trp Glu Gly Asn Pro Glu Met Glu Thr Leu Gln
 145                 150                 155                 160
 Arg Ile Tyr Gly Ile Ser Phe Pro Asp Asn Lys Met Met Arg Asp Trp
                 165                 170                 175    
 Glu Lys Phe Gln Glu Glu Ala Lys Asn Arg Asp His Arg Lys Ile Gly
             180                 185                 190        
 Lys His Asp Ser Gln Val Ile Trp Gln Phe Gln Arg Lys Glu Glu Lys
         195                 200                 205            
 Thr Asn Ser Ala Lys Tyr Leu Leu Val Leu Gln Val His Arg Cys Lys
     210                 215                 220                
 Thr Asp Val Ala Asp Glu Gln Glu Gln Gly Leu Ile Val Arg Val Thr
 225                 230                 235                 240
 Lys Leu
        



      <210> 1516
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1516
 Met Gly Phe Val Gly Thr Trp Ala Cys Ile Ala Pro Cys Gly Ala Ser
   1               5                  10                  15    
 His Met Ser Val Leu Leu His Asn Arg Ser Gln Cys Val Gln Lys Leu
              20                  25                  30        
 Gly Met Arg Cys Gly Leu Gln Gly Ala Pro Pro Pro Arg Ala Gly Trp
          35                  40                  45            
 Pro Ala Ala Thr Ser Ser Arg Ile Ala Val Thr Cys Trp Leu Thr Ala
      50                  55                  60                
 Ile Leu Val Leu Ala Leu Cys Glu Glu Val Thr Val Tyr Arg Met Thr
  65                  70                  75                  80
 Gly Gly Asn Lys Gln His Arg Thr Trp Ile Leu Gly Thr Arg Glu Thr
                  85                  90                  95    
 Gly Leu Leu Pro Gly Glu Pro Phe Gln Ala Val Ala Tyr Glu Asp Gly
             100                 105                 110        
 Val Asp Glu Thr Thr Ala Asn Leu Leu Thr
         115                 120        



      <210> 1517
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 1517
 Met Lys Val Thr Ser Pro Met Leu Leu Leu Ala Glu Gly Leu Leu Pro
   1               5                  10                  15    
 Val Leu Val Arg Gly Thr Gly Thr His Pro Ser Ala Cys Asp Pro Asp
              20                  25                  30        
 Leu His Pro Pro Arg Pro Ile Pro Gly Gln Gly Leu Glu Cys Phe Gln
          35                  40                  45            
 Cys Tyr Gly Val Leu Asp Pro Ser Leu Cys His Pro Val Ser Tyr Pro
      50                  55                  60                
 Met Gln Ala Gln Ser Cys Pro Ser Ser Val Val Thr Gly Thr Ile Asp
  65                  70                  75                  80
 Glu Ile Glu Asp Arg Leu Ile Asp Ser Lys Ile Glu Lys Leu Asp Met
                  85                  90                  95    
 Thr Cys Cys Glu Asn Ser Leu Arg Asn Lys Ala Ala Thr Val Arg Arg
             100                 105                 110        
 Gly Leu Trp Cys Gln Ala Val Arg Glu Leu Leu Leu Ser Leu Ser Pro
         115                 120                 125            
 Phe Leu Trp Ala Leu Leu
     130                



      <210> 1518
      <211> 123
      <212> PRT
      <213> Homo sapiens


      <400> 1518
 Met Val Ala Ser Phe Arg Glu Ser Arg Val Leu Leu Leu Gly Phe Val
   1               5                  10                  15    
 Val Arg Val Leu Thr Phe Asp Phe Leu Thr Gln Val Val Arg Val Gly
              20                  25                  30        
 Ser Glu Cys Gly Asp Glu Leu Ile Arg Leu Tyr Ser Phe Thr Asp Glu
          35                  40                  45            
 Lys Ala Asn Tyr Leu Gln Gln Gly Asn Asn His Arg Pro Ile His Lys
      50                  55                  60                
 Asp His Phe Trp Leu Ile Tyr Gly Thr Leu Phe Tyr Leu Val Asn Phe
  65                  70                  75                  80
 Gly Arg Tyr Leu Ser Leu Arg Asp Gly Pro Thr Cys Ser Val Arg Ala
                  85                  90                  95    
 Pro Ser Ala Ala Thr Glu Glu Leu Ala Ala Pro Gln His Phe Gly Phe
             100                 105                 110        
 Ile Pro Phe Ser Ala Pro Val Leu Met Lys Thr
         115                 120            



      <210> 1519
      <211> 218
      <212> PRT
      <213> Homo sapiens


      <400> 1519
 Met Leu Leu Thr Gln Ser Leu Phe Gly Gly Leu Phe Thr Gln Thr Arg
   1               5                  10                  15    
 Met Lys Phe Gly Gly Ser Gly Asp Leu Pro Trp Glu Ile Asn Pro Leu
              20                  25                  30        
 Ser Ser Cys Ser Leu Leu His Glu Lys Ala Pro Pro Thr Thr Ser Gly
          35                  40                  45            
 Pro Gln Thr Asp Gln Pro Lys Lys His Leu Thr Asn Phe Lys Ser Asp
      50                  55                  60                
 Val Asp Arg Ala Ala Glu Arg His Leu Gln Gly Val Met Leu Ala Gln
  65                  70                  75                  80
 Met Gly Glu Glu Gly Thr Leu Leu Thr Ser Asp His Glu Lys Arg Val
                  85                  90                  95    
 Gly Asn Lys Phe Cys Ile Asp Lys Gly Glu His Asn Lys Leu Arg Leu
             100                 105                 110        
 Thr Tyr Lys His Glu Tyr Asn Ser Lys Tyr Ser Gly Thr Asn Gly Gly
         115                 120                 125            
 Arg Glu His Leu Gly Arg Leu Leu Ala Ala Ala Ala Phe Gln Met Glu
     130                 135                 140                
 Ala Lys Ala Glu Thr Arg Arg Ala Cys Gly Leu Asp Asn Gly Gly Gly
 145                 150                 155                 160
 Lys Lys Thr Lys Gly Asn Thr Arg Val Trp Ala Arg Gly Ser Pro Asn
                 165                 170                 175    
 Lys Glu Arg Cys Ser Val Asn Phe Gly Gly Glu Thr Leu Asn Ala Lys
             180                 185                 190        
 Gln Glu Thr Thr Lys Asn Lys Leu Arg Cys Leu Ser Val Leu Pro Lys
         195                 200                 205            
 Thr Asn Lys Ala Ser Gly Asp Leu Gln Thr
     210                 215            



      <210> 1520
      <211> 220
      <212> PRT
      <213> Homo sapiens


      <400> 1520
 Met Phe Leu Gln Phe Ala Leu Gly Lys Val Ala Ile Leu Ala His Phe
   1               5                  10                  15    
 Thr Tyr Phe Gly Lys Asn Leu Ser Phe Ala Lys Gly Ser Ser Phe Arg
              20                  25                  30        
 Arg Ala Asp Asn Lys Leu Trp Glu Leu Thr Ser Ser Trp Val Leu Pro
          35                  40                  45            
 Met Ala Ala Thr Thr Val Ser Phe Trp Lys Ile Trp Lys Glu Lys Thr
      50                  55                  60                
 Thr Lys Thr Gln Glu Thr Thr Thr Ile His Gln Asn Asn Asn Lys Ile
  65                  70                  75                  80
 Tyr Phe Glu Thr Val Asn Ser Leu Lys Tyr Glu Ser Leu Pro Tyr Lys
                  85                  90                  95    
 Met Arg Gln Lys Gly Gln Glu Lys Lys Thr Ile Glu Val Phe Lys Glu
             100                 105                 110        
 Asn Gln Gln Thr Arg Glu Ala Ser Gly Pro Pro Gly Gly Ala Ala Gly
         115                 120                 125            
 Arg Ala Pro Pro Pro Pro Asp Pro Pro Pro Gln Ile Thr Ser Gln Arg
     130                 135                 140                
 Val Ala Gly Phe Val Phe Pro Leu Pro Pro Ser Arg Gln Pro Pro Gly
 145                 150                 155                 160
 Leu Gln Gln Pro Pro Asp Pro Pro Leu Arg Pro Pro Leu Lys Arg Arg
                 165                 170                 175    
 Arg Ala Pro Glu Gly Val Asp Ser Ala Met Leu His Arg Asn Leu Leu
             180                 185                 190        
 Gln Pro Gln Thr Asn Ser Ser Ser Ser Ser Gly Gly Gly Gly Ser Ser
         195                 200                 205            
 Ser Ser Ser Ile Ser Ser Ser Ser Phe Ser Gln Cys
     210                 215                 220



      <210> 1521
      <211> 97
      <212> PRT
      <213> Homo sapiens


      <400> 1521
 Met Val Pro Arg Ala Leu Trp Lys Leu Leu Pro Ile Leu Gly Tyr Leu
   1               5                  10                  15    
 Gln Pro Asp Leu Gly Val Val Val Thr Ser Thr Ala Ile Arg His Pro
              20                  25                  30        
 Pro Gln Ser Ala Glu Gln Thr Leu Leu Pro Leu Lys Phe Phe Asp Thr
          35                  40                  45            
 Thr Phe Thr Asn Ser Gln Arg Lys Val Ala Pro Asp Thr Glu Ala Arg
      50                  55                  60                
 Leu Trp Ser Asp Lys Lys Pro Arg Asp Arg Arg Ser Tyr Ser Val Ile
  65                  70                  75                  80
 Ile Gln Leu Ser Thr Glu Asp Cys Val Pro Lys Lys Arg Cys Pro Pro
                  85                  90                  95    
 Pro
    



      <210> 1522
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 1522
 Met Cys Ser Ile Pro Arg His Leu Leu Pro Leu Val Leu Pro Val Ala
   1               5                  10                  15    
 Leu Leu Leu Cys Ala Leu Glu Pro Leu Lys His Arg Gly Leu Glu Arg
              20                  25                  30        
 Leu Ile Arg His Pro Gln His Leu Glu Arg Gly Leu Ala His Lys Thr
          35                  40                  45            
 Ala Met Asn Gly Gln Pro
      50                



      <210> 1523
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1523
 Met Ala Pro Leu Ser Ile Ile Pro Thr Leu Tyr Val His Val Tyr Pro
   1               5                  10                  15    
 Leu Leu Pro Leu Ile Ala Pro Phe Ile Glu Lys Leu Ser Val His Val
              20                  25                  30        
 Ile Glu Gly Asp His Arg Thr Leu Leu Glu Gly Ser Gly Leu Glu Ser
          35                  40                  45            
 Ile Ile Ser Thr Leu Ala Glu Pro Arg Val Ser Val Arg Glu Gly
      50                  55                  60            



      <210> 1524
      <211> 244
      <212> PRT
      <213> Homo sapiens


      <400> 1524
 Met Ala Arg Ala Val His Trp Pro Leu Leu Val Met Ala Gly Val Ala
   1               5                  10                  15    
 Gly Thr Gln Gly Arg Lys Trp Lys Leu Lys Asn Glu Val Thr Leu His
              20                  25                  30        
 Ile Pro Tyr Met Ala Lys Ile Gln Asn Thr Asn Asp Thr Lys Tyr Trp
          35                  40                  45            
 Arg Val Glu Glu Gln Glu Phe Ser Phe Ile Ala Val Arg Cys Phe Leu
      50                  55                  60                
 Thr Glu Thr Thr Leu Asn Tyr Gln Lys Ile Leu Ser Val Arg Pro Gly
  65                  70                  75                  80
 Thr Lys Leu Ala Thr Ala Ser His Val Ser Gly Leu Gly Leu Gln Thr
                  85                  90                  95    
 Pro Pro Phe Gly Leu Ala Gln His Leu Ile Arg Pro His Ala Phe Leu
             100                 105                 110        
 Ala Pro Lys Asp Pro Leu Thr Ser Phe Thr Glu Arg Asn Ser Arg Ser
         115                 120                 125            
 Gly Lys Thr Arg Cys Arg Ser Lys Lys Cys Ala Met Arg Val Val Lys
     130                 135                 140                
 Ser Tyr Ser Ala Ile Leu Pro Lys Lys Arg Glu Ser Val Leu Thr Lys
 145                 150                 155                 160
 Thr Leu Leu Val Ala Pro Thr Asn Glu Gln Thr Asp Pro Val Leu Arg
                 165                 170                 175    
 Met Cys Cys Gly Lys Thr Gly Leu Lys Lys Gly Ala Gly Phe Thr Leu
             180                 185                 190        
 Glu Ser Arg Gly Gln Arg Arg Met Arg Ala Gly Cys Pro Thr Leu Cys
         195                 200                 205            
 Val Arg Ala Arg Val Thr Glu Thr Asp Pro Ser Ile Cys Arg Phe Val
     210                 215                 220                
 Gly Ile Leu Phe Leu Met Leu Ala Phe Asp Tyr Gln Ser Val Ala Cys
 225                 230                 235                 240
 Ser Leu Phe Arg
                



      <210> 1525
      <211> 53
      <212> PRT
      <213> Homo sapiens


      <400> 1525
 Met Phe Phe Ser Ala Ala Leu Arg Ala Arg Ala Ala Gly Leu Thr Ala
   1               5                  10                  15    
 His Trp Ile Ser Phe Glu Asp Arg Arg Ser Glu Gly Gly Thr Ser Arg
              20                  25                  30        
 Phe Lys Pro Ser Asp Leu Asp Ala Phe Arg Leu Gln His Thr Gly Glu
          35                  40                  45            
 Leu Trp Leu Ala Ser
      50            



      <210> 1526
      <211> 201
      <212> PRT
      <213> Homo sapiens


      <400> 1526
 Met Tyr Trp Ala Ser Thr Thr Pro Ala Thr Arg Ala His Thr Leu Ala
   1               5                  10                  15    
 Leu Ala Thr Ala Thr Thr Leu Ala Thr Val Ala Arg Cys Met Asp Gly
              20                  25                  30        
 Ala Leu Met Ser Val Pro Ala Gly Lys Lys His Arg Asp Trp Asp Ser
          35                  40                  45            
 Gln Lys Arg Arg Ile Pro Glu His His Gly Gln Ala Ser Asp Ala Pro
      50                  55                  60                
 Pro Pro Leu Gly Pro Thr His Thr His Arg Gly Glu Arg Ala Gly Ser
  65                  70                  75                  80
 Phe Leu Gly Glu Ser Leu Gln Leu Cys Gly Ala Gly Gly Ala Ala Trp
                  85                  90                  95    
 Trp Gly Ser Leu Phe Ala Arg Asp Val Glu Gln Leu Ser Ala Gly Gly
             100                 105                 110        
 Arg Glu Gly Ile Val Lys Leu Lys Val Ala Phe Leu Cys Thr Val Arg
         115                 120                 125            
 Ser Cys Ser Leu Cys Ser Ile Thr Gly Thr Leu Ser Gly Val His Lys
     130                 135                 140                
 Ala Lys Phe Ala Glu Arg Gly Phe Ala Glu Arg Trp Gly Arg Ala His
 145                 150                 155                 160
 Leu Thr Trp His Gln Ile Ser His His Ala Pro Phe Pro Phe Pro Asp
                 165                 170                 175    
 Tyr Ala Phe His Pro Phe Ile Val Ala Ile Leu His Ser His Glu Asp
             180                 185                 190        
 Asp Tyr Ala Val Ser Cys Glu Ser Ser
         195                 200    



      <210> 1527
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 1527
 Met Val Leu Val Ala Trp Pro Gly Ala Leu Cys Trp Val Gly Glu Gly
   1               5                  10                  15    
 Tyr Trp Gln His Leu Trp Phe Gly Glu Gly Val Arg Pro Pro Arg Cys
              20                  25                  30        
 Phe Ala Thr Cys Ile Ala Pro Asn Gln Cys Lys Gly Ile Leu Lys Val
          35                  40                  45            
 Leu Val Leu Met Lys Ala Met Leu Met Arg Lys Leu Pro Lys Trp Ala
      50                  55                  60                
 Leu Phe Gln Glu Leu Asp Cys His Val Ser Arg Asp Pro Gln Val Ala
  65                  70                  75                  80
 Asn Ser Ala Leu Met Cys Leu Lys Arg Gln Gly Ser Gly Cys Met Arg
                  85                  90                  95    
 Ser Arg Leu Ser Glu Glu Asp Glu Tyr Gly Arg Asp Lys Glu Asp Phe
             100                 105                 110        
 Pro Val Ile Glu Glu Arg Leu Pro Ser Gln Gly Leu Trp Phe Trp Ser
         115                 120                 125            
 Ser Ser Ser Arg Val Val Phe Pro Val Ser Gly Ser Thr Leu Asn Ile
     130                 135                 140                
 Gly Arg Thr Ser Glu Trp Trp Pro Lys Val Pro Arg Leu Pro Ala Leu
 145                 150                 155                 160
 Pro Lys Leu Pro Phe Asn Gln Leu Gly Glu Glu Gly Glu Gly Ala Glu
                 165                 170                 175    
 Ala Val Gly Phe Ser Val Asp Gly Lys Thr Glu Arg Ile Glu Gly Val
             180                 185                 190        
 Arg Gln Val Ala Glu Lys Arg Met Gly Arg Ala Thr Asp Val Gly Ser
         195                 200                 205            
 Ile Gln Glu Ala Cys
     210            



      <210> 1528
      <211> 227
      <212> PRT
      <213> Homo sapiens


      <400> 1528
 Met Pro Trp Ala Ala Ser Ser Leu Ala Met Pro Trp Ala Ala Ser Ser
   1               5                  10                  15    
 Leu Ala Met Pro Trp Ala Ala Ser Ser Leu Ala Met Pro Trp Ala Ala
              20                  25                  30        
 Ser Ser Leu Ala Met Pro Leu Ser Ala Ala Ser Leu Ala Met Ser Cys
          35                  40                  45            
 Thr Val Ser Ser Leu Ala Met Ser Leu Trp Pro Val Ala Glu Gln Ile
      50                  55                  60                
 Asn Phe Thr Thr Glu Val Gly His Thr Gly Leu Cys Gly Pro Pro Leu
  65                  70                  75                  80
 Leu Leu Glu Phe Val Ser Val Gly Pro Thr Gly Gly Asn Ser Gly Ala
                  85                  90                  95    
 Gly Ala Thr Pro Leu Ala Leu Gln Val Leu His Leu Ser Ser Gly Asp
             100                 105                 110        
 Asn Lys Ala Asp Pro Gly Met Ala Leu Lys Leu Leu Leu Gly Ile Tyr
         115                 120                 125            
 Met Val Glu Ser Met Glu Asn Cys Phe Asn Ser Ser Phe Met Ser Ser
     130                 135                 140                
 Val Gly Ile Gly Leu Val Ile Leu Val Ile Val Phe Cys Ser Asp Phe
 145                 150                 155                 160
 Asn Lys Lys Leu Val Glu Glu Pro Glu Gly Leu Trp Lys Arg His Pro
                 165                 170                 175    
 Ala Val Asp Thr Glu Val Gln Glu Asn Asn Gly Ala Pro Ser Glu Lys
             180                 185                 190        
 Ala Val Pro Arg Asn Lys Glu Ala Leu Met Val Ala Arg Gly Lys Asp
         195                 200                 205            
 Ser Cys His Glu Ala Val His Met Arg Val Ser Gly Cys Ile Asp Thr
     210                 215                 220                
 His Thr Ser
 225        



      <210> 1529
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1529
 Met Pro Gly Arg Leu Thr Leu Leu Ala Ser Val Leu Ala Thr Gly Cys
   1               5                  10                  15    
 Ile Lys Gln Thr Leu Leu Leu Gln Tyr Leu Thr Thr Cys Thr Ile Gln
              20                  25                  30        
 Gln Ile Ser Ser Thr Thr Lys Ser Gln Gln Met Val Gln Leu Val Phe
          35                  40                  45            
 Asn Glu Gln Lys Ala Phe Val
      50                  55



      <210> 1530
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 1530
 Met Pro Phe Leu Thr Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Ser
   1               5                  10                  15    
 Thr Ile Thr Ile Val Ala Gly Pro Asp Phe Asn Pro Ala Ser His Ile
              20                  25                  30        
 Ile Pro Asp Thr Thr Pro Asp Pro His Asp Cys Ile Ser Leu Ile His
          35                  40                  45            
 Leu Thr Phe Ile Pro Phe Pro His Ile Ser Phe Phe Pro Val Pro His
      50                  55                  60                
 Pro Asp His Thr Trp Phe Ile Asp Gly Ser Ser Thr Arg Pro Asn Cys
  65                  70                  75                  80
 His Ser Pro Ala Lys Ala Gly Tyr Ala Ile Val Ser Ser Thr Phe Ile
                  85                  90                  95    
 Ile Glu Ala Thr Ala Leu Pro Pro Ser Thr Thr Ser Gln Gln Ala Lys
             100                 105                 110        
 Leu Ile Ala Leu Thr Gln Ala Leu Thr Leu Ala Lys Gly Leu Leu Val
         115                 120                 125            
 Asn Ile Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Gln Tyr His His
     130                 135                 140                
 Ala Val Ile Trp Ala Glu Arg Asn Phe Leu Thr Thr
 145                 150                 155    



      <210> 1531
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 1531
 Met Thr Leu Gly Phe Gly Leu Ser Arg Arg Pro Ser Leu Leu Val Gly
   1               5                  10                  15    
 Gly Leu Glu Pro Arg Leu Trp His Gln Ala Asp Leu Ala Ala Asp Gln
              20                  25                  30        
 Leu Ser Glu Val Gly Gln Gly Gly Phe Asn Asn Ile Thr Pro Val Phe
          35                  40                  45            
 Lys Arg Gly Asn Cys Ile Glu Gly Gly Glu Gly Thr Cys Gln Gly His
      50                  55                  60                
 Thr Asp Asp Lys Arg Arg Ala Leu Ser Cys Gln Pro Thr Lys Gln Met
  65                  70                  75                  80
 Val Gln Gln Pro Asp Leu Lys Glu Gly Pro Gly Glu Glu Glu Lys Gly
                  85                  90                  95    
 Ser Leu Ala Ser Leu Ser Phe Gly Ser Gly Ser Gly Pro Arg Asp His
             100                 105                 110        
 Tyr Ser Ile Cys Tyr Pro Thr Leu Pro
         115                 120    



      <210> 1532
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1532
 Met Ser Arg Leu Pro Val Ala His Leu Ser Val Cys Ile Leu Gly Phe
   1               5                  10                  15    
 Val Asn Val Leu Asn Gln Lys Met Pro Glu Tyr Ser Gln Ser Thr Asn
              20                  25                  30        
 Leu Ser Val Val Leu Phe Leu Trp Asp His Val Gln Ser Leu Asn Ser
          35                  40                  45            
 Ile Thr Cys Val Ser Thr Val Ile Lys Leu Asn Cys Ser Trp Gly Cys
      50                  55                  60                
 Tyr Leu Trp Leu Thr Ser Met Thr
  65                  70        



      <210> 1533
      <211> 181
      <212> PRT
      <213> Homo sapiens


      <400> 1533
 Met Asp Lys Phe Trp Trp His Ala Ala Trp Gly Leu Cys Leu Val Pro
   1               5                  10                  15    
 Leu Ser Leu Ala Gln Ile Gly Glu Cys Pro Pro Gln Pro Gly Gln Gln
              20                  25                  30        
 Asp Gly Cys Gly Val Leu Ser Ala Asp Pro Ala Ala Ala Pro Pro Ala
          35                  40                  45            
 Glu Ser Ala Leu Gly Asp Trp Ser Gln Pro Gln Ser Arg Glu Lys Ser
      50                  55                  60                
 Leu Asp Thr Arg Ala Thr Ser Gly Thr Leu Glu Leu Gly Leu Gln Tyr
  65                  70                  75                  80
 Leu Ile Gln Thr Gly Ser Val Leu Cys Gly Gly Tyr Gly Gly Glu Gly
                  85                  90                  95    
 Leu Arg Val Ser Leu Arg Tyr Val Phe Ile Ser Ser Arg Lys Thr Asn
             100                 105                 110        
 Glu Tyr Ser Lys Leu Gly Pro Val Lys Trp Gly Val Ala Glu Lys Ile
         115                 120                 125            
 Pro Lys Asn Val Glu Thr Ala Leu Glu Leu Gly Asn Arg Pro His Phe
     130                 135                 140                
 Gln Ile Phe Gly Thr Val Leu Thr Leu Glu Val Leu Pro Glu Thr Arg
 145                 150                 155                 160
 Ser Leu Pro Pro Ala Pro Cys Phe His Gly Pro Phe Ala Gln His His
                 165                 170                 175    
 Leu Glu Glu Val Gln
             180    



      <210> 1534
      <211> 165
      <212> PRT
      <213> Homo sapiens


      <400> 1534
 Met Pro Gly Pro Thr Gly Thr Lys Phe Ser Ile Phe Val Phe Trp Val
   1               5                  10                  15    
 Ala Val Leu Ser His Gln Asp Asp Trp Val Leu Ala Arg Pro Asn Arg
              20                  25                  30        
 Leu His Asp Gly Lys Lys Ala Lys Gln Leu Ile Ala Gln Arg Lys Leu
          35                  40                  45            
 Glu Asp Arg Trp Cys Ile Arg Gly Arg Ala Glu Leu Glu Gln Asp Ile
      50                  55                  60                
 Leu Asp Ser Ala Ala Val Thr Ile Ile Gln Lys Trp His Ile Lys Gly
  65                  70                  75                  80
 Arg Pro Ala Leu His Pro Ala Gly Val Leu Gly His Val Glu Ala Pro
                  85                  90                  95    
 Phe Ser Leu Val Leu Gln Leu Glu Arg Ser Arg Phe Leu Lys Asn Arg
             100                 105                 110        
 Trp Glu Ser Ala Gly Ala Arg Tyr Pro Gly Arg Glu Glu Gly Asn Glu
         115                 120                 125            
 Ile Arg His Arg Gly Cys Gly Asp Arg Gly Ser Gln Glu Ala Ala Val
     130                 135                 140                
 Arg Cys Lys Gly Pro Pro Thr Arg Pro Ala Val Glu Leu Pro Pro Arg
 145                 150                 155                 160
 Leu Pro Val Leu Ser
                 165



      <210> 1535
      <211> 248
      <212> PRT
      <213> Homo sapiens


      <400> 1535
 Met Ser Ile Lys Leu Phe Leu Gln Thr Val Val Pro Leu Leu Cys Gly
   1               5                  10                  15    
 Ser Ile Leu Thr Phe Gly Leu Trp Ile Gly Thr Leu Leu Pro Ala Pro
              20                  25                  30        
 Thr Ser Val Lys Asn His Gln Glu Lys Leu Pro Gly Trp Arg Lys Glu
          35                  40                  45            
 Lys Asp Leu Ser Leu Trp Leu Ser Leu Ser Lys Gln Gln Lys Arg Asn
      50                  55                  60                
 Ser Trp Thr Leu Met Phe His Lys His Lys Pro Val Ala Ser Pro Val
  65                  70                  75                  80
 Arg Lys Ala Val Gly Glu Glu Ala Gly Ala Glu Arg Ala Thr Pro His
                  85                  90                  95    
 Asn Leu Asp Met Ala Thr Leu Ser Tyr Thr Arg Asp Gly Ser Glu Ser
             100                 105                 110        
 Ser Val Trp Ile Gln Glu His Val Leu Glu Trp Asn Ala Lys Glu Asp
         115                 120                 125            
 Ala Cys Ser Arg Gly Gln Ser Ala Leu Arg Ala Arg Ser Pro Gly Arg
     130                 135                 140                
 Ala Val Ile Gln Ala Gln Gly Trp Asn Lys Ala Gly Phe Pro Val Gln
 145                 150                 155                 160
 Thr Pro Ile Gly Pro Ile Asn Thr Arg Gly Trp Thr Arg Thr Lys Asp
                 165                 170                 175    
 Met Arg Ile Val Trp Gly Cys Arg His Val Gln Ala Lys Lys Leu Ala
             180                 185                 190        
 Gln Gln Ile Ala Cys Leu Glu Asp Phe Gly Trp Lys Ala Ser Ser Glu
         195                 200                 205            
 Ser His His Leu Lys Asp Leu Leu Ser Ser Lys Val Met Thr Val Val
     210                 215                 220                
 Ala Arg Asn Met Val Thr Ser Ser Tyr Gln Glu His Ile Ser Lys Ile
 225                 230                 235                 240
 Leu Tyr His Arg Arg Thr Lys Thr
                 245            



      <210> 1536
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 1536
 Met Val Ile Pro Val Ala Phe Leu Pro Leu Pro Leu Thr Cys Leu Ala
   1               5                  10                  15    
 Thr Trp Leu Pro Pro His Asn Pro Thr Cys Val Glu His His Gly Ala
              20                  25                  30        
 Leu His Leu Gln Ile Lys Arg Leu Gly Trp Glu Ser Gln Cys Phe Ala
          35                  40                  45            
 Gly Tyr Val Asn Asp Thr Pro Gly Gln Thr Asn Pro Val Asn Ser Met
      50                  55                  60                
 Gln Ile Lys His His Leu Leu Gln Arg Leu His Ile Pro Gly Cys Gly
  65                  70                  75                  80
 Cys His Trp Leu Lys Pro Gln Glu Ser Gln Arg Lys Gly Val Ser Asp
                  85                  90                  95    
 Pro Leu Asp Ala Ile Cys Arg Gly Gln Leu Pro Glu Leu Arg Lys Glu
             100                 105                 110        
 Asp Arg Asn Ala Asp Arg Gly Ser Gly Arg Arg Met Glu Lys Val Gln
         115                 120                 125            
 Cys Thr Thr Ser Phe Trp Asp Ile Glu Phe Trp Leu Pro Val Gly Thr
     130                 135                 140                
 Tyr Glu Phe Thr Tyr Arg Ile Pro Phe Val Asn Val Leu Ile Ile Tyr
 145                 150                 155                 160
 Leu Val Pro Glu Cys His Cys Arg Pro Arg Ala Phe Ile Ser Val His
                 165                 170                 175    
 Ile Cys Ala Gly Cys Arg Glu Gln
             180                



      <210> 1537
      <211> 321
      <212> PRT
      <213> Homo sapiens


      <400> 1537
 Met Met Ile Ala Gly Ile Ala Ala Leu Leu Leu Trp Leu Leu Val Leu
   1               5                  10                  15    
 Ala Ala Pro Ile Ala Gly Glu Leu Ala Ala Ala Val Arg Arg Pro Gly
              20                  25                  30        
 Pro Arg Ala Pro Phe Pro Thr Gly Met Gly Glu Arg Asn Ser Gly Phe
          35                  40                  45            
 Val Glu Leu Ser Gly Arg Trp Gly Arg Val Phe Thr Val Arg Leu Gly
      50                  55                  60                
 Pro Arg Pro Ala Val Val Leu Cys Gly Tyr Ala Ala Leu Arg Asp Ala
  65                  70                  75                  80
 Leu Val Leu Gln Ala Asp Ala Val Ser Gly Arg Gly Ser Met Ala Val
                  85                  90                  95    
 Phe Glu Arg Phe Thr Arg Gly Asn Arg Ile Leu Phe Ser Asn Arg Pro
             100                 105                 110        
 Cys Trp Trp Thr Leu Arg Asn Phe Ala Leu Gly Ala Pro Lys Lys Phe
         115                 120                 125            
 Gly Leu Gly Thr Arg Thr Ile Glu Ala Arg Val Leu Asp Glu Ala Ala
     130                 135                 140                
 Cys Leu Leu Asp Glu Phe Gln Ala Thr Ile Ala Ser Ala Trp Pro Gly
 145                 150                 155                 160
 Gly Arg Lys Gly Leu Val Trp Glu Trp Pro Leu Asp Cys Gln Asp Gly
                 165                 170                 175    
 Ala Thr Gly Lys Tyr Leu Gly Gly Arg Lys Pro Val Ser Pro Trp Gly
             180                 185                 190        
 Trp Leu Gly Ala Gly Pro Arg Val Met Thr Thr Val Leu Phe Leu Pro
         195                 200                 205            
 Pro Gly Ala Pro Phe Asp Pro Val Arg Leu Leu Gly Asn Ala Val Ser
     210                 215                 220                
 Asn Val Thr Cys Ser Cys Leu Arg Glu Pro Leu Trp Leu Arg Gly Pro
 225                 230                 235                 240
 Gly Val Pro Glu Val Leu Asn Leu Leu Ser Asp Asn Phe Arg Ile Met
                 245                 250                 255    
 Ser Ser Lys Trp Gly Glu Gly Gln Glu Leu Asp Pro Val Val Gly Gln
             260                 265                 270        
 Arg Pro Val Pro Ser Pro Asp Asp His Val Gln Trp Pro Tyr Thr Asn
         275                 280                 285            
 Ala Val Leu Leu Glu Ile Gln Arg Phe Ile Ser Val Val Pro Arg Thr
     290                 295                 300                
 Leu Thr Leu Asp Thr His Leu His Ser His Cys Leu Ala Lys Gly Ala
 305                 310                 315                 320
 His
    



      <210> 1538
      <211> 243
      <212> PRT
      <213> Homo sapiens


      <400> 1538
 Met Arg Thr Lys Thr Gln Gln Leu Arg Phe Arg Gln Arg Lys Gln Ile
   1               5                  10                  15    
 Pro Glu Ser Ala Gln Ser Leu Leu Leu Leu Leu Leu Leu Leu Ser Ala
              20                  25                  30        
 Ala Ser Ala Ala Gly Gly Ile Ala Asn Thr Leu Thr Gln Ala Leu Ala
          35                  40                  45            
 Leu Asn Arg Asp Met Phe Ala Ala Glu Cys Pro Arg Ser Glu Ile Ala
      50                  55                  60                
 Val Glu Ile Thr Thr Thr Glu Leu Gly Ser Leu Asn Ala Met Asp Phe
  65                  70                  75                  80
 Gly Ile Ala Gly Thr Lys Trp Trp Gln Leu Met Pro Lys Thr Arg Phe
                  85                  90                  95    
 Tyr Leu Asn Gly Trp Met Phe Leu Leu Met Cys Ser Ala Ala Glu Phe
             100                 105                 110        
 Ser Val Gln Ala Leu Thr Gly Ala Gln Lys Leu Arg Phe Ile Phe Ile
         115                 120                 125            
 Ser Ser Ser Val Thr Ala Pro Gly Ala Ser Gly Ser Arg Asn His Leu
     130                 135                 140                
 Gln Val Ala Leu Lys Val Arg Leu Val Arg Pro Thr Val Asn Arg Lys
 145                 150                 155                 160
 Leu Leu Gly Ala Gly Thr Gly Ser Leu Pro Arg Lys Glu Ala Arg Arg
                 165                 170                 175    
 Glu Arg Phe Leu Asp Gly Asp Gln Asp Gly Asp Glu Gly Pro Arg Gln
             180                 185                 190        
 Pro Ser Met Gly Leu Pro His Lys Gln Val Gln Asn Arg Ala Met Ala
         195                 200                 205            
 Lys Val Val Ile Thr Phe Ala Pro Thr Asn Ala Met Gln Leu Ala Arg
     210                 215                 220                
 Ser Pro Lys Thr Leu Asn Phe Met Lys Ile Ile Gly Glu Met Glu Ser
 225                 230                 235                 240
 Val Leu Glu
            



      <210> 1539
      <211> 96
      <212> PRT
      <213> Homo sapiens


      <400> 1539
 Met Gly Met Ser Leu Val Ala Ile Leu Val Leu Thr Ala Lys Pro His
   1               5                  10                  15    
 Gly Ser Lys Gln Gln Lys Val Val Thr Asn Gln Gly Phe Ser Ser Pro
              20                  25                  30        
 Leu Leu Lys Ala Val Val Asp Pro Lys Asp Thr Ala Gly Met Met Gly
          35                  40                  45            
 Pro Ala Asp Lys Val Lys Lys Val Thr Arg Gly Gly Lys Leu Thr Asp
      50                  55                  60                
 Gly Thr Tyr Phe Gly Lys Ile Thr Lys Gln Arg Asp Leu Lys Ala Gly
  65                  70                  75                  80
 Phe Pro Ser Val Leu Glu Ala Leu Cys Gln Glu Glu Asp Pro Arg Ala
                  85                  90                  95    





      <210> 1540
      <211> 175
      <212> PRT
      <213> Homo sapiens


      <400> 1540
 Met Arg Leu Pro Ser Leu Val Leu Trp Thr Lys Gln Thr Val Glu Trp
   1               5                  10                  15    
 Leu Leu Gly Val Cys Ile Lys Gly Gln Thr Val Ala Phe Thr Leu Cys
              20                  25                  30        
 Thr Ile Thr Pro Leu Leu His Ser Pro Tyr Pro Phe Phe Asn Leu Phe
          35                  40                  45            
 Val Ser Gly Glu Leu Leu Ile Arg Leu Leu Cys Leu Leu Met Ile Cys
      50                  55                  60                
 His Val Ile Leu Lys Gly Thr Gly Ala Leu Gly Arg Gly Trp Gln Pro
  65                  70                  75                  80
 Gly Cys Glu Arg Ala Lys Lys Glu Gln Glu His Gln Leu Gly Cys Leu
                  85                  90                  95    
 Ser Leu Ser Pro Asp Thr Cys His Ser Pro Ser Arg Gly Thr Trp Pro
             100                 105                 110        
 Tyr Gln Arg Asp Met Lys Cys Cys Pro Asn Gly Gly Arg Asn Ala Ala
         115                 120                 125            
 Thr Leu His Ala Ala Glu Ser Leu Leu Arg Lys Met Gly Arg His Val
     130                 135                 140                
 Ser Glu Asn Ile Tyr Leu Ser Pro Thr Phe Ser Ser Tyr Lys Gly Thr
 145                 150                 155                 160
 Val Trp Gly Pro Ala Gly Leu Val Gly Pro Ala Asp Arg Glu His
                 165                 170                 175



      <210> 1541
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1541
 Met Arg Pro Lys Ile Thr Asp Gly Ser Gly Ser Ala Phe Gln Trp Asp
   1               5                  10                  15    
 Leu Ala Arg Phe Trp His Gln Phe Cys Gln Leu Thr Thr Ile Leu Tyr
              20                  25                  30        
 Trp Leu Trp Tyr Cys Ile Phe Tyr Ser Ala Cys Asn Asp Met Tyr Lys
          35                  40                  45            
 Gly Leu Leu Ser Thr Lys Val Ser Val Met Cys Glu Ser Pro Gly Phe
      50                  55                  60                
 Leu Asn
  65    



      <210> 1542
      <211> 196
      <212> PRT
      <213> Homo sapiens


      <400> 1542
 Met Val Gln Asp Ala Gly Ser Cys Gly Ser Leu Ala Pro Pro Arg Pro
   1               5                  10                  15    
 Leu Val Leu Leu Leu Leu Thr Arg Phe Ala Gln Ala Ala Ser Ser Asp
              20                  25                  30        
 Gly Trp Gly Leu Cys Tyr Pro Gln His Gln Ala Thr Ser Val Gly Ala
          35                  40                  45            
 His Gly Gln Ala Arg Gln Leu Gly Pro Trp Val Trp Pro Trp Pro Asp
      50                  55                  60                
 Ala Pro Ser Thr Gly Ser Arg Leu Leu Leu Leu Leu Leu Ser Ser Met
  65                  70                  75                  80
 Asp Ser Leu Asp Cys Met Val Gly Val Ser Asp Gln Cys Asn Trp Lys
                  85                  90                  95    
 Pro Thr Asn Thr Gly Arg Ser Leu Val Ser Asn Tyr Gln Ser Ile Thr
             100                 105                 110        
 Cys Gly Arg Ser Lys Leu Leu Glu Asp Gly Ser Trp Val Glu Ser Val
         115                 120                 125            
 Ala Tyr Glu Leu Pro Val Asn Arg Lys Ile Gln Ala Asp Asp Glu Glu
     130                 135                 140                
 Ser Leu Ser Arg Met Val Val Gly Lys Phe Gln Gly Leu Cys Ala Thr
 145                 150                 155                 160
 Trp Thr Gly Ala Asn Gly Arg Lys Trp Cys His Asn Ile Gln Lys Lys
                 165                 170                 175    
 Asn Lys Asn Thr Ala Trp His Leu Thr Ala His Glu Glu Phe Pro Pro
             180                 185                 190        
 Ser Ser Leu Lys
         195    



      <210> 1543
      <211> 207
      <212> PRT
      <213> Homo sapiens


      <400> 1543
 Met Pro Leu Gln Arg Trp Ile Phe Arg Gly Glu Gly Leu Cys Val Trp
   1               5                  10                  15    
 Leu Lys Glu Trp Thr Leu Ser Thr Gly Gln Ala Phe Gln Gly Ala Ser
              20                  25                  30        
 Gln Leu Gln Cys Lys Pro Thr Ala Leu Ala Gly Arg Gly Pro Val Pro
          35                  40                  45            
 His Met Ala Leu His Gly Thr Gln Glu Gln Trp Gln Val Val Met Glu
      50                  55                  60                
 Pro Ala Ser Leu Ile Asn Thr Ile Pro Thr Arg Lys Cys Ser Gly Val
  65                  70                  75                  80
 Val Leu Ser Asn Thr Ile Ala Thr Ser Cys Cys Asp Tyr Arg Ala Leu
                  85                  90                  95    
 Ser Val Gly Leu Glu Leu Arg Cys Ala Pro Ser Arg Leu Leu Ser Thr
             100                 105                 110        
 Ala Cys Arg Gln Gln Lys Leu Gln Ile Ser Gly Arg Ser Lys Gly Cys
         115                 120                 125            
 Ser Arg Lys Thr Ser Gly Leu Glu Asp Gln Gly Leu Thr Lys Asp Ala
     130                 135                 140                
 Glu Pro Lys His Ser Thr Phe Ser Phe Ser Gly Leu Ser Pro Leu Cys
 145                 150                 155                 160
 Gly Arg Gly Pro Leu Arg Pro Met Gly Thr Leu Glu Val Phe Tyr Ala
                 165                 170                 175    
 Lys Val Pro Thr Ala Ser Gly Thr Val Leu Ser Leu Leu Gly Trp Thr
             180                 185                 190        
 Ser Glu Asn Gly Arg Ala Pro Asp Phe Gly Gln Cys Gln Gly His
         195                 200                 205        



      <210> 1544
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 1544
 Met Asp Phe Ser Ala Leu Ile Trp Pro Thr Ile Phe Ser Cys Gln Trp
   1               5                  10                  15    
 Ala Ser Val Phe Leu Val Leu His Met Lys Met Ser Arg Ser Pro Leu
              20                  25                  30        
 Leu Lys Glu Arg Val Pro Asp Leu Ser Trp Ala His Gln Ile Gln Tyr
          35                  40                  45            
 Leu Pro Gly Ile Arg Lys Arg Trp Arg Glu
      50                  55            



      <210> 1545
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 1545
 Met Glu Glu Glu Thr Arg Val His Ile Ser Thr Asp Pro Leu Cys Leu
   1               5                  10                  15    
 Leu Val Phe Ala Leu Leu Leu Cys Cys Ser Lys Asn Val Leu Glu Val
              20                  25                  30        
 Val Ser Ser Ser Ser Ser Asn Thr Gly Gln Gly Ser Pro Arg Ala Ala
          35                  40                  45            
 Ser Ala Phe Asp Leu Val His Ile Gln Thr Leu Pro Val Leu His Thr
      50                  55                  60                
 Leu
  65



      <210> 1546
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1546
 Met Pro Gly Leu Thr Leu Gln Gly Tyr Val Ile Leu Gln Ile Leu Val
   1               5                  10                  15    
 Asp Leu Gly Asp Thr Leu Ser Pro Ile Arg Trp Arg Arg His Val Thr
              20                  25                  30        
 His Met Val Trp Pro Leu Met Thr Glu Gln Ala Met Asp Thr Gly Pro
          35                  40                  45            
 Arg Arg Asp His Ser Leu Thr Gly His Glu His Glu Phe Arg Tyr Met
      50                  55                  60                
 Pro Gln Lys Asp Glu Pro Gly Trp Phe Cys Asn Gln Gln Pro Leu Gln
  65                  70                  75                  80
 Thr Ser Leu Gly Gly Ser Lys Glu Leu Thr Pro Asp Glu Glu Lys Asp
                  85                  90                  95    
 Gln Pro Gln Thr His Ser Ser Ser Ser His Phe Gln Thr His Gly Arg
             100                 105                 110        
 Arg Gln Asp Pro Leu Lys Glu Glu Pro Ser Glu Lys Lys Gly Lys Ala
         115                 120                 125            
 Lys Arg Asn
     130    



      <210> 1547
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 1547
 Met Asn Asp Lys Ala Ile Phe Lys Thr Leu Phe Leu Phe Phe Pro Gln
   1               5                  10                  15    
 Ser Leu Val Leu Ile Ser Lys Leu Pro Tyr Ile His Phe Phe His Thr
              20                  25                  30        
 Val Leu Lys Gln Ile Ala Pro Glu Tyr Phe Glu Lys Asn Glu Pro Tyr
          35                  40                  45            
 Leu Glu Ala Gly Thr Asp Ser His Met Ser
      50                  55            



      <210> 1548
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1548
 Met Val Phe His Thr Ala Leu Pro Leu Thr Lys Ala Leu Thr Leu Arg
   1               5                  10                  15    
 Leu Lys Asn Cys Asn Ser Gly Leu Met Leu Thr Glu Phe Thr Gly Leu
              20                  25                  30        
 Thr Met Phe Pro Ile Ile Gln Gly Trp Gly Lys Val Leu Gln Lys Ala
          35                  40                  45            
 Val Tyr Ala Leu Asn Gln Arg Pro Ile Tyr Gly Ala Val Ser Pro Thr
      50                  55                  60                
 Asp Arg Ile His Met Ser Arg Asn Gln Gly Val Glu Val Glu Val Ala
  65                  70                  75                  80
 Pro Leu Thr Ile Thr Pro Gly Asp Pro Leu Ala Lys Val Leu Leu Pro
                  85                  90                  95    
 Phe Pro Val Thr Leu Leu Ser Ala Gly
             100                 105



      <210> 1549
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1549
 Met Glu Phe Phe Cys Trp Phe Trp Asp Phe Trp Gly Trp Leu Leu Asn
   1               5                  10                  15    
 Met Ile Arg Pro Lys Asp Ala Lys Asp Pro Pro Ser Asn Ser Met Glu
              20                  25                  30        
 Asn Thr Asp Ser Pro Arg Cys Glu Leu Phe Arg Glu Leu Cys Lys Ile
          35                  40                  45            
 Asn Ala Phe Asp Thr Pro Asp Ser Leu Leu Met Arg Asp Lys Glu Phe
      50                  55                  60                
 Ser Asp Phe Val His Asn Ile Phe Asp His Met Trp Arg Thr Lys Glu
  65                  70                  75                  80
 His Asn Glu Ala Gly Trp Leu Leu Leu Ser Leu Val Asp Lys Val Met
                  85                  90                  95    
 Lys Glu Asn Tyr Glu Leu Arg Asp Ser Val Ser Trp Leu Gln Lys Gln
             100                 105                 110        
 Ile Met Ser Leu Lys Tyr Ala Asn Ile Ala Leu Ser Glu Ser Leu Ile
         115                 120                 125            
 Ser Cys Arg Glu Arg Ala Lys Ile Val Lys Lys Gln Thr Gln Val Ala
     130                 135                 140                
 Asp Leu Gln
 145        



      <210> 1550
      <211> 69
      <212> PRT
      <213> Homo sapiens


      <400> 1550
 Met Met Ala Tyr Leu Val Val Ser Gly Leu Phe Leu Thr Arg Leu Arg
   1               5                  10                  15    
 Arg Pro Ile Glu Ser Ser Arg Asn Lys Lys Gly Pro Ser Arg Leu Val
              20                  25                  30        
 Cys Leu Tyr Glu Ser Lys Glu Thr Phe Pro Lys Ser Pro Thr Thr Asp
          35                  40                  45            
 Phe Pro Ser Tyr Leu Ile Gly Trp Asn Gly Tyr Leu Thr Met Pro Lys
      50                  55                  60                
 Ala Ile Thr Ala Lys
  65                



      <210> 1551
      <211> 306
      <212> PRT
      <213> Homo sapiens


      <400> 1551
 Met Gly Leu Leu Pro Arg Ala Pro Leu Gly Leu Cys Phe Leu His Pro
   1               5                  10                  15    
 Ser Ala Ala Leu Leu Ser His Pro Ser Cys Gly Ser Ser Asp Pro Lys
              20                  25                  30        
 Cys Ser Ser Thr Gln His Ser Arg Ser Asp Gln Val Lys Thr Ile Pro
          35                  40                  45            
 Ala Phe Ser Asn Lys Ser Asn Thr Arg Thr Tyr Thr Leu His Pro Ser
      50                  55                  60                
 Pro Tyr Thr Glu Lys Asn His His Arg Lys Gly Ala Pro Glu Gly Asn
  65                  70                  75                  80
 Ser Ser Ala Pro Ser Ser His Leu Pro Ala Leu Ala Cys Ile Cys Ile
                  85                  90                  95    
 His Pro His Thr Ala Asn Pro Leu Pro Ala Leu Met Gly Gln Asp Gln
             100                 105                 110        
 Gly Ala Glu Ile Lys Gly Lys Asn Arg Glu Gln Arg Cys Arg Thr Gln
         115                 120                 125            
 Leu Ser Leu Glu Lys Tyr Leu Thr Tyr Thr Ile Val Thr Tyr Val Leu
     130                 135                 140                
 Val His Val Pro Gln Gln Thr Gln Leu Leu Gly Val Ser Gly Ile Ser
 145                 150                 155                 160
 Gly Ile Cys Thr Lys Met Leu Ser Leu Lys Ser Gly Val Ala His Ser
                 165                 170                 175    
 Pro Val Ala His Glu Asn Pro Glu Phe Phe Val Arg Leu Asp Gly Thr
             180                 185                 190        
 Leu Thr Tyr Asn Asp Ala Ala Val Leu Glu Asn Ser Leu Ala Val Val
         195                 200                 205            
 Gln Lys Val Lys Cys Arg Val Thr Thr Trp Pro Cys Ser Ser Thr Pro
     210                 215                 220                
 Met Gly Met Tyr Val His Thr Lys Thr Cys Thr Arg Met Leu Thr Val
 225                 230                 235                 240
 Thr Pro Phe Val Leu Ala Lys Val Arg Leu Thr Ala Ser Arg Arg Glu
                 245                 250                 255    
 Gln Arg Val Ser Gly Ser Glu Thr Ala Phe Leu Gly Leu Glu Val Lys
             260                 265                 270        
 Asp Val Arg Leu Val Gln Tyr Leu Pro Ser Ala Gln Gly Lys Pro Gly
         275                 280                 285            
 Glu Ser Leu Ala Pro Gly Pro Gly Gly Phe Cys Pro Val Arg Ser Glu
     290                 295                 300                
 Gly Gly
 305    



      <210> 1552
      <211> 268
      <212> PRT
      <213> Homo sapiens


      <400> 1552
 Met Leu Leu Pro Arg Lys Leu Thr Leu Ser Tyr Phe Leu Ala Leu Ile
   1               5                  10                  15    
 Ile Ala Gln Lys Glu Gln Gly Leu Leu Arg Asn Arg Gly Ser Val Gln
              20                  25                  30        
 Pro Glu Gly Met His Arg Ala Glu Glu Asp Pro Cys Gly Cys Gly Leu
          35                  40                  45            
 Phe Ser Arg Pro Lys Asp Lys Ala Val Cys Ala Gly Leu Ile Cys Thr
      50                  55                  60                
 Ala Leu Ala Arg Met Ala Leu Leu Arg Glu Thr Asn Arg Ser Asn Ala
  65                  70                  75                  80
 Lys Leu Pro Ser Gln Phe Gln Ser Gln Arg Gln Ala Arg Ala Thr Val
                  85                  90                  95    
 Gln Thr Gln Leu Pro Met Ser Thr Lys Lys Arg Arg Lys Leu Glu Met
             100                 105                 110        
 Gln Leu Val Leu Pro Cys Trp Pro Leu Ser Phe Ser Pro Pro Gly Leu
         115                 120                 125            
 Arg Arg Thr Ser Cys Val Cys Trp Lys Glu Gly Asp Glu Val Ile Gln
     130                 135                 140                
 Leu Asn Lys Pro Gly Thr Asn Thr Thr Lys Arg Asn Glu Arg Ile Thr
 145                 150                 155                 160
 Glu Pro Ser Cys Pro Asp Ala Arg Glu Trp Gly Pro Val Gly Trp Gly
                 165                 170                 175    
 Arg Ala Ala Arg Asp Pro Arg Thr Arg Thr His Glu Gly Ser Ile Ser
             180                 185                 190        
 Asn Arg Pro Gly Gly Val Asp Leu Gly Pro Leu Gly Leu Thr Ser Ser
         195                 200                 205            
 His Gly Glu Asp Thr Asp Ala Glu Asp Thr Ser Glu Arg Ala Trp Gly
     210                 215                 220                
 Lys Leu Thr Arg Arg Arg Asn Met Ser Leu Pro Cys Ser Arg His Gly
 225                 230                 235                 240
 Val Pro Gly Lys Pro Ala Ser Glu Leu Tyr Phe Arg Ala Leu Cys Lys
                 245                 250                 255    
 Gln Cys Tyr Leu Asp Lys Arg Thr Gln Ser Asn Ala
             260                 265            



      <210> 1553
      <211> 353
      <212> PRT
      <213> Homo sapiens


      <400> 1553
 Met Gly Phe Trp Phe Leu Asn Trp Thr Arg Ser Ala Phe Gln Gly Asp
   1               5                  10                  15    
 Val Ala Leu His Pro Val Asp Asn Asn Asp Arg Gln Thr His Gly His
              20                  25                  30        
 Pro Arg Leu Ser Leu Val Gln Leu Glu Val Gly Gly Ser Glu Gly His
          35                  40                  45            
 Arg Thr Arg Val Val Lys Ala Glu Glu Leu Ser Leu Ser Gly Ser Ile
      50                  55                  60                
 Ala Val Ile Leu Cys Leu Gln Lys Glu Arg Cys Glu Ile Gln Gly Leu
  65                  70                  75                  80
 Ile Ile Leu Lys Phe Leu Arg Lys Gly Asn Gly Thr Arg Ile Ala Glu
                  85                  90                  95    
 Thr Ile Leu Lys Lys Lys Thr Lys Val Gly Gly Thr Ile Leu Ser Asp
             100                 105                 110        
 Phe Lys Met Asn Lys Ala Arg Val Leu Glu Ile Val Trp Tyr Leu Trp
         115                 120                 125            
 Ser Asn Arg Cys Met Asn Gln Trp Asn Arg Ile Glu Asp Pro Glu Thr
     130                 135                 140                
 Asp Pro Gln Thr Asn Gly Ala Leu Ala Ile Gly His Pro Gln Thr Lys
 145                 150                 155                 160
 Gln Ile Lys Leu Thr Asn Arg Pro Gln Ser Leu Asn Leu Asn Leu Arg
                 165                 170                 175    
 Pro Asp Met Lys Met Asn Ser Lys Trp Ile Val Asp Leu Asn Val Lys
             180                 185                 190        
 Ser Gln Gly Cys Glu Asn Cys Leu Gln Lys Gly Ser Phe Gln Leu Val
         195                 200                 205            
 Phe Thr Ser Phe Gly Arg Glu His Ala Ala Asn Val Asn Gln Glu Ser
     210                 215                 220                
 Lys Ser Gln Thr Glu Glu Ala Leu Asn Gly Val Ile Gly Gly Arg Ser
 225                 230                 235                 240
 Asp Phe Gln Leu Ser Val His Asp Gly Ser Lys Pro Thr Pro Thr Met
                 245                 250                 255    
 Glu Thr Gln Pro Val Phe Asp Gly Asp Asp Ile Tyr Gly Arg Lys Arg
             260                 265                 270        
 Ser Pro Trp Ser Gly Lys Ser Phe Cys Glu Glu Pro Gly Leu Glu Leu
         275                 280                 285            
 Asp Leu Glu Ser Gly Gly Glu Glu Ser Glu Cys Ser Arg Gln Gly Ala
     290                 295                 300                
 Gly Met Asp Lys Arg Gly Met Arg Trp Gln Asp Tyr Glu Gln Lys Ile
 305                 310                 315                 320
 Tyr Asp Phe Glu Pro Ala Gly Arg Ile Leu His Asp Asn Gln Leu Met
                 325                 330                 335    
 Ser Val Leu Ser Leu Val Pro Phe Lys Leu Thr Cys Ser Pro Ala Leu
             340                 345                 350        
 Ser
    



      <210> 1554
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1554
 Met Glu Leu Gly Val Gln Ser Gly Arg Leu Phe Met Thr Phe Phe Thr
   1               5                  10                  15    
 Val Pro Val His Tyr Phe Ala Phe Arg Ala Cys Cys Ser Cys Ser Ser
              20                  25                  30        
 Ser Lys Lys Ser Arg Pro Leu Ser Ser Thr Ala Asn Thr Phe Ser Pro
          35                  40                  45            
 Arg His Leu Leu Ser His Leu Arg Asn Lys Gln Pro Ala Ser Gln Glu
      50                  55                  60                
 Glu Met Val Glu Thr Ile Thr Tyr Ile Ile Arg Lys Ile Lys Gln Glu
  65                  70                  75                  80
 Gln Asp Thr Lys Lys Glu Gln Leu Glu Asn Lys Lys Glu Phe Leu Val
                  85                  90                  95    
 Leu Lys Asp Ile Ala Gly Cys Ala Tyr Leu Lys Gly Arg Cys Tyr Ala
             100                 105                 110        
 Val Leu Tyr Phe Ala Ala Ser Phe Pro Pro Asp Val Thr Thr Gly Pro
         115                 120                 125            
 Ala Gly Tyr Ser Cys Gly Pro
     130                 135



      <210> 1555
      <211> 159
      <212> PRT
      <213> Homo sapiens


      <400> 1555
 Met Gly Trp Glu Ser Val Leu Gln Glu Leu Trp Ala Leu Val Phe Leu
   1               5                  10                  15    
 Met Cys Gln Cys Gln Cys Glu Gly Asp Tyr Thr Asp Asp Glu Gly Glu
              20                  25                  30        
 Glu Asn Gln Ile Val Asn Thr Thr Gly Glu Asn Leu Lys Ser Val Leu
          35                  40                  45            
 Met Asn Ile Lys Gln Gly Glu Glu Asn Gln Gly Ser Ser Leu Pro His
      50                  55                  60                
 Arg His Glu Arg Thr Ser Ser Met Thr Thr Ser Pro Ile Thr Ser Pro
  65                  70                  75                  80
 Gly Leu Gln Arg Gln Pro Pro Gln Ser Phe Leu Val Met Tyr Gln Arg
                  85                  90                  95    
 Ile Pro Asp Gly Arg Asn Pro Glu Thr Ser Ser Ser Glu Ser Asn Lys
             100                 105                 110        
 Leu Gln Leu Arg Cys Pro Thr Gly Pro Lys Pro Pro Leu Arg Leu Gly
         115                 120                 125            
 Val Leu Phe Gln Ala Gln Val Ile Val Ser Arg Ile Tyr Val Leu Ala
     130                 135                 140                
 Ala Val Lys Leu Met Leu Ala Cys Val Phe Lys Ala Asn Arg Thr
 145                 150                 155                



      <210> 1556
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 1556
 Met Lys Arg Ser Thr Ser Cys Gly Ala Val Tyr Arg Met Leu Val Ser
   1               5                  10                  15    
 Ile Arg Ile Leu Arg Ser Leu Leu Phe Leu Arg Gly Pro Arg Ala Leu
              20                  25                  30        
 Gly Gly Gly Leu Gly Gln Ile Trp Tyr Leu Val Thr Arg Ser Asn Ser
          35                  40                  45            
 Thr Ile Cys Cys Ile Trp Asn Gly Lys Gly Ala Gln Asn Pro Gly Arg
      50                  55                  60                
 Thr Glu Asp Ile Arg Cys Tyr Asp Asn Lys Met Glu Ser Thr Arg Ala
  65                  70                  75                  80
 Gln Glu Leu
            



      <210> 1557
      <211> 297
      <212> PRT
      <213> Homo sapiens


      <400> 1557
 Met Arg Pro Ser Gly Thr Ala Gly Ala Ala Leu Leu Ala Leu Leu Ala
   1               5                  10                  15    
 Ala Leu Cys Pro Ala Ser Arg Ala Leu Glu Glu Lys Lys Ala Ala Gln
              20                  25                  30        
 Asp Arg Arg Gln Trp Ala Lys Ala Gly Cys Trp Ser Pro Arg Ser Ser
          35                  40                  45            
 Phe Pro Ser Val Glu Ser Gln Pro Arg Pro Gly Ser Trp Glu Asn Ser
      50                  55                  60                
 Ser Thr Thr Thr Cys Gly Ser Arg Gly Gly Val Val Leu Ala Ala Val
  65                  70                  75                  80
 Ser Phe Leu Val Gly Lys Arg Gln Gly Leu Ala Arg Gln Ser Arg Ser
                  85                  90                  95    
 Ile Ala Ile Leu Asp Lys Pro Leu Ile Leu Lys Phe Thr Leu Ile Lys
             100                 105                 110        
 Asn Cys Leu Asn Ser Asn Cys Ile Ser Leu Met Ala Lys Ser Thr Lys
         115                 120                 125            
 Ile Tyr Leu Ala Lys Ala Glu Gln Lys Val Gln Gln Phe Asp Glu Val
     130                 135                 140                
 Gly Gln His Glu Glu Ser Val Leu Leu Leu Tyr Thr Asp Gly Asp Ala
 145                 150                 155                 160
 Glu Ile Gln Asn Ser Pro His Val Ser Arg Phe Glu Ser His Cys Ala
                 165                 170                 175    
 Leu Leu Trp Ile Arg Ile Arg Gln Leu Ser Leu Val Pro Thr Arg Lys
             180                 185                 190        
 Val Ala Tyr Trp Lys Val Leu Leu Gln Gly Ala Leu Ser Ser Ala Ser
         195                 200                 205            
 Gly Leu Glu Val Gly Ser Val Glu Thr Thr His Ser Ile Ser Gln Thr
     210                 215                 220                
 Asn Thr Lys Asp Val Met Gly Met Asp Val Asn Thr Gly Val Asn Thr
 225                 230                 235                 240
 Arg Ser Ala Pro Arg Glu Glu Trp Ser Lys Arg Met Glu Trp Gln Met
                 245                 250                 255    
 Lys Leu Trp Asp Leu Ser Lys Leu Leu Lys Gln Leu His Leu His Phe
             260                 265                 270        
 Leu Val Gly Thr Met Glu Leu Ser Ala Val Leu Ser Ser Glu Gly Cys
         275                 280                 285            
 Gly Leu Asp Glu Val Cys Trp Cys Met
     290                 295        



      <210> 1558
      <211> 170
      <212> PRT
      <213> Homo sapiens


      <400> 1558
 Met Ala Leu Leu Ser Thr Ser Ala Ala Pro Val Thr Leu Phe Leu Leu
   1               5                  10                  15    
 Ile Val Thr Leu Glu Trp Leu Gln Asp Glu His Asp Pro Leu Glu Met
              20                  25                  30        
 Glu Thr Ser Ser Glu Asp Ala Leu Leu Arg Ser Leu Ile Gly Arg Phe
          35                  40                  45            
 Asp His His Gln Ser Thr Glu Val Trp Glu Ser Arg Asn Leu Ser Phe
      50                  55                  60                
 Gln Glu Ser Val Ala Phe Glu Asp Val Ala Val Tyr Phe Thr Thr Lys
  65                  70                  75                  80
 Glu Trp Ala Ile Met Val Pro Ala Glu Arg Ala Leu Tyr Arg Asp Val
                  85                  90                  95    
 Met Leu Glu Asn Tyr Glu Ala Val Ala Phe Val Val Leu Lys Asp Ile
             100                 105                 110        
 Leu Arg Ser Cys Ser His Thr Tyr Thr Gly Cys Ser Gln Leu Gln Ser
         115                 120                 125            
 Leu Phe Ile Phe Pro Cys Ser Gly Leu Glu Val Ala Glu Asp Leu Ala
     130                 135                 140                
 Pro Glu Pro Leu Trp Ser Ile Ser Gly His Lys Gly Gly Glu Leu Glu
 145                 150                 155                 160
 Ser Trp Met Ser Val Leu Asn Ser Ser Ser
                 165                 170



      <210> 1559
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 1559
 Met Leu Leu Cys Met Thr His Phe Met Ala Arg Trp Val Arg Lys His
   1               5                  10                  15    
 Pro Val His Asp Lys Gln Phe Arg Phe His Ala Ala Leu Asp Leu Leu
              20                  25                  30        
 Gly His Met Ala Gln Val Ala Glu Gln Phe Ala Arg Gln Pro Gly Pro
          35                  40                  45            
 Val Ala Glu Pro Ser Leu Ile Leu Asp Pro Thr Gln Asn Trp Gln Pro
      50                  55                  60                
 Phe Gly Ser Leu Asp Lys Trp Ala Arg Val Thr His Pro Asn Glu Glu
  65                  70                  75                  80
 Cys Val Ala Ser Lys Ile Gln Thr Ser Pro Leu Gly Ile Val Pro Pro
                  85                  90                  95    
 Ser Trp Leu
            



      <210> 1560
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 1560
 Met Ala Tyr Leu Ser Lys Val Ile Asp Val Val Ala Lys Thr Trp Pro
   1               5                  10                  15    
 His Cys Leu Trp Val Val Val Ser Val Ala Val Leu Val Ser Glu Ala
              20                  25                  30        
 Val Lys Ile Ile Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp
          35                  40                  45            
 Val Asp Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp Leu Pro Asp Asn
      50                  55                  60                
 Cys Leu Leu Lys Tyr Gln Pro Leu Leu Leu Glu Gly Pro Val Leu Ile
  65                  70                  75                  80
 Glu Ala Val Lys Leu Gln Ile Val Leu Gln Met Glu Pro Gln Met Gln
                  85                  90                  95    
 Ser Met Thr Lys Ile Tyr Arg Gly Pro Leu Asp Gln Pro Ala Ser Pro
             100                 105                 110        
 Cys Ser Asn Val Asn Asp Ile Glu Gly Thr Pro Pro Lys Glu Ile Ser
         115                 120                 125            
 Thr Ala Ser Pro Leu Leu Cys Pro Asn Ser Ala Gly Ser Ser
     130                 135                 140        



      <210> 1561
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 1561
 Met Leu Trp Leu Ala Leu Ser Ser Ala Ala Ala Ala Gln Pro Ser Gly
   1               5                  10                  15    
 Arg Phe Phe Gln Gly Asn Ser Ser Ser Trp Leu Val Asn Pro His Asp
              20                  25                  30        
 Glu Phe Pro Asn Leu Ser Thr Glu Glu Asp Met Lys Ala Glu Thr Leu
          35                  40                  45            
 Gly Ile Asn Asn Ile Asn Thr Ser Pro Pro Gly Lys Ala Glu Lys Val
      50                  55                  60                
 Gln Glu Ile Met Leu Leu Asp Glu Gly Glu His Ala Gly Asn Leu Ile
  65                  70                  75                  80
 Glu Ser Ala Asp Phe Gly His Asp Asp Asn Pro Thr Ile Thr Ala Thr
                  85                  90                  95    
 Gly Asp Gln Leu Ser Arg Val Leu Cys Ile Gly Glu Gly Leu Asp Ser
             100                 105                 110        
 Val Ala Val Lys Glu Thr Lys Gly Tyr
         115                 120    



      <210> 1562
      <211> 176
      <212> PRT
      <213> Homo sapiens


      <400> 1562
 Met Ile Val Val Gly Val Met Leu Gly Ser Ser Tyr Val Ser Val Ser
   1               5                  10                  15    
 Phe Leu Ser His Cys Glu Tyr Phe Ile Ala Asn Lys Ile Gly Tyr Lys
              20                  25                  30        
 Asn Val Tyr Ser Phe Phe Ala Leu Asn Thr Leu Ser Phe Ser Arg Leu
          35                  40                  45            
 Ser Leu Phe His Pro Ser Pro Arg Lys Gly Arg Leu Val Gln Leu Leu
      50                  55                  60                
 Asn Thr Tyr Leu Pro Arg Val Glu Pro Ala Tyr Val Lys Thr Ser Asp
  65                  70                  75                  80
 Glu Thr Lys Ile Ala Lys Gly Ser Leu Arg Gly Leu Lys Leu Glu Glu
                  85                  90                  95    
 Ile Lys Leu Cys Lys His Cys Phe Pro Arg Thr Ser Gln Lys Glu Tyr
             100                 105                 110        
 Val Met Pro His Asp Asn Lys Leu Leu Gln Ser Thr Ser Asn Thr Thr
         115                 120                 125            
 Lys Ile Asn Leu Met Ser Cys Tyr His Val Arg Glu His Tyr Lys Ile
     130                 135                 140                
 Ile Glu Asn Asn Asn Asn Ala Val Ile Phe Thr Ile Tyr Leu Pro Phe
 145                 150                 155                 160
 Ile Asn Leu Asp Asp Asp His Leu Leu Phe Asn Phe Val Gln Ser Thr
                 165                 170                 175    





      <210> 1563
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1563
 Met Ala Pro Leu Tyr Phe Leu Thr Phe Ala Ala Leu Leu Pro Leu Cys
   1               5                  10                  15    
 Ala Leu Arg Leu Ser Thr His Pro Gln Arg Lys Thr Arg His Leu Phe
              20                  25                  30        
 Phe Val Glu Arg Ile Gly Phe Arg Ile Gln Arg Pro Val Gln Gln Arg
          35                  40                  45            
 Arg Ser Leu Cys Arg Gly Leu Leu Pro Asp Phe His Leu Leu Ile Ile
      50                  55                  60                
 Ala Ser Leu Ile Asn Asn Ile Ser Gly Thr Leu Thr Phe Arg His Ala
  65                  70                  75                  80
 Leu Phe Arg Lys Arg Phe Arg His His Ala Tyr Pro Thr Pro Arg Ala
                  85                  90                  95    
 Gly Val Tyr Asp Pro Thr Ala Asn Ala Asn Ser His Tyr Trp Gln His
             100                 105                 110        
 Pro Gln Gln His Gly Leu Gly Gly Ser Glu Lys Ile Lys Asp Leu Val
         115                 120                 125            
 Asp Pro Gln His Ser Met Ala Ala
     130                 135    



      <210> 1564
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1564
 Met Ser Phe Asp Trp Met Ala Tyr Ile Val Ser His Ile Leu Leu Val
   1               5                  10                  15    
 Val Gly Phe Tyr Tyr Met Phe Leu Asn Asn Asp Val Phe Ile Leu Val
              20                  25                  30        
 Cys Arg Ile Ile Phe Ser Thr Pro Leu Ala Val Ile Ala Tyr Phe Leu
          35                  40                  45            
 Ile Trp Phe Val Pro Asp Phe Pro His Gly Gln Thr Tyr Trp Tyr Leu
      50                  55                  60                
 Leu Phe Tyr Cys Leu Phe Glu Thr Met Val Thr Cys Phe His Val Pro
  65                  70                  75                  80
 Tyr Ser Ala Leu Thr Met Phe Ile Ser Thr Glu Gln Thr Glu Arg Asp
                  85                  90                  95    
 Ser Ala Thr Ala Tyr Leu Phe Ile Arg Asp Lys Leu Met Gly Ala Ala
             100                 105                 110        
 Gly Asn Arg Arg Thr Gly Lys Asp Arg Glu Ser Ala Val Ser Gly Lys
         115                 120                 125            
 Val Thr Asp Arg Thr Val Arg Thr Trp Ile Gly Glu Ala Val Ala Ala
     130                 135                 140                
 Ala Ala Ala Asp Gly Val Thr Phe Ser Val Pro Val Thr Pro His Thr
 145                 150                 155                 160
 Phe Arg His Ser Tyr Ala Met His Met Leu Tyr Ala Gly Ile Pro Leu
                 165                 170                 175    
 Lys Val Leu Gln Ser Leu Met Gly His Lys Ser Ile Ser Ser Thr Glu
             180                 185                 190        
 Val Tyr Thr Lys Val Phe Ala Leu Asp Val Ala Ala Arg His Arg Val
         195                 200                 205            
 Gln Phe Ala Met Pro Glu Ser Asp Ala Val Ala Met Leu Lys Gln Leu
     210                 215                 220                
 Ser
 225



      <210> 1565
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 1565
 Met Phe Pro Ala His Gln Gln Met Ala Val Leu Asp Ala Val Leu Ala
   1               5                  10                  15    
 Phe Asp Leu Arg Phe Leu Val Thr Arg Lys Phe Trp Arg Pro Trp Ser
              20                  25                  30        
 Arg Gly Leu Asn His Ile Thr Ser Glu Gln Glu Ala Arg Val Glu Asn
          35                  40                  45            
 Cys Val Leu Pro Ser Ser Phe Thr Val Phe Asn Gly Trp Asn Lys Cys
      50                  55                  60                
 Val Lys Val Gly Ser Leu Val Leu Gly Lys Leu His Ser Gly Ser Gly
  65                  70                  75                  80
 Asn His Cys Asp Asn Ser Ser Gln Ser Ser Gln Val Trp Gly Leu Thr
                  85                  90                  95    
 Thr Gln Ala Pro Arg Pro Ile Pro Ala Leu Arg Ser Ser Gln Gly Ala
             100                 105                 110        
 Gly Leu Asp Asp Glu Phe Ile Ser Pro Gln Leu Cys Ala Phe Asn Cys
         115                 120                 125            
 Ser Val Ser Ala Ala Glu Ala Phe Gly Arg Ile Phe Arg Ala
     130                 135                 140        



      <210> 1566
      <211> 353
      <212> PRT
      <213> Homo sapiens


      <400> 1566
 Met Pro Val Arg Lys Ile Ile Arg Ile Lys Leu Val Tyr Gln Ile Leu
   1               5                  10                  15    
 Thr Ala Phe Phe Thr His Ile Arg Asp His Ser Gly Ile Phe Ala Asp
              20                  25                  30        
 Pro Arg Ile Ala Ile Met Trp Pro Pro Val Arg Arg His Phe Ala Thr
          35                  40                  45            
 Asp Lys Ala His Leu Phe Cys Gln Ile Arg Thr Arg Thr Cys Gly Phe
      50                  55                  60                
 Ile Asn Arg Lys Pro Asp His Phe Ala Glu Gln Ile Pro Gln Ser Gln
  65                  70                  75                  80
 Ile Asp Thr Arg Asn Arg Ile His His Gln Ala Thr Arg Ala Gly Val
                  85                  90                  95    
 Ile Gln Gly Gly Thr Glu His Leu Ile Val Asp Gln Phe Asp Ile Thr
             100                 105                 110        
 Asp Thr Phe Thr Leu Asn Glu Thr Val Lys Met Phe Phe Asp Asn Lys
         115                 120                 125            
 Thr Ala His Phe Thr Gly Cys Arg Asn Gly Glu Ser Gly Leu Ala Val
     130                 135                 140                
 Phe Cys Phe Asp Phe Asn Asn Gln Arg Ala Arg Pro Asp Leu Ala Lys
 145                 150                 155                 160
 Glu Met Gly Phe Ile Gly Gly Lys Met Pro Thr His Trp Gly Pro His
                 165                 170                 175    
 Asp Gly Asp Ala Gly Ile Arg Lys Asp Ala Ala Met Val Ala Asp Met
             180                 185                 190        
 Arg Glu Lys Cys Gly Glu Asp Phe Trp Leu Met Leu Asp Cys Trp Met
         195                 200                 205            
 Ser Gln Asp Val Asn Tyr Ala Thr Lys Leu Ala His Ala Cys Ala Pro
     210                 215                 220                
 Tyr Asn Leu Lys Trp Ile Glu Glu Cys Leu Pro Pro Gln Gln Tyr Glu
 225                 230                 235                 240
 Ser Tyr Arg Glu Leu Lys Arg Asn Ala Pro Val Gly Met Met Val Thr
                 245                 250                 255    
 Ser Gly Glu His His Gly Thr Leu Gln Ser Phe Arg Thr Leu Ser Glu
             260                 265                 270        
 Thr Gly Ile Asp Ile Met Gln Pro Asp Val Gly Trp Cys Gly Gly Leu
         275                 280                 285            
 Thr Thr Leu Val Glu Ile Ala Ala Ile Ala Lys Ser Arg Gly Gln Leu
     290                 295                 300                
 Val Val Pro His Gly Ser Ser Val Tyr Ser His His Ala Val Ile Thr
 305                 310                 315                 320
 Phe Thr Asn Thr Pro Phe Lys Glu Phe Leu Met Thr Ser Pro Asp Cys
                 325                 330                 335    
 Ser Thr Met Arg Pro Gln Phe Asp Pro Arg Gly Tyr Ser Arg Val Gly
             340                 345                 350        
 Pro
    



      <210> 1567
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1567
 Met Pro Asn Phe Phe Ile Asp Arg Pro Ile Phe Ala Trp Val Ile Ala
   1               5                  10                  15    
 Ile Ile Ile Met Leu Ala Gly Gly Leu Ala Ile Leu Lys Leu Pro Val
              20                  25                  30        
 Ala Gln Tyr Pro Thr Ile Ala Pro Pro Ala Val Thr Ile Ser Ala Ser
          35                  40                  45            
 Tyr Pro Gly Ala Asp Ala Lys Thr Val Gln Asp Thr Val Thr Gln Val
      50                  55                  60                
 Ile Glu Gln Asn Met Asn Gly Ile Asp Asn Leu Met Tyr Met Ser Ser
  65                  70                  75                  80
 Asn Ser Asp Ser Thr Gly Thr Val Gln Ile Thr Leu Thr Phe Glu Ser
                  85                  90                  95    
 Gly Thr Asp Ala Asp Ile Ala Gln Val Gln Val Gln Asn Lys Leu Gln
             100                 105                 110        
 Leu Ala Ile Lys Leu Asn Ala Ala Arg Ser Ser Ala Ala Arg
         115                 120                 125    



      <210> 1568
      <211> 201
      <212> PRT
      <213> Homo sapiens


      <400> 1568
 Met Val Leu Ala Tyr Leu His Gln Ala Ala Ala Glu Leu Ala Leu Leu
   1               5                  10                  15    
 Leu Asp Cys Glu Val Ile Glu Ala Asn Lys Leu Thr Phe Cys Ile Ser
              20                  25                  30        
 Gln Phe Gly Phe Trp Glu Asn Arg Ala Phe Cys Asn His Arg His Met
          35                  40                  45            
 Ser Leu Gly Asn Arg Gly Pro Gln Gly Val Asp Gly Lys Met Pro Pro
      50                  55                  60                
 Lys Leu Gly Ser Ala Ala Phe Val Gly Ser Ile Ile Gly Leu Phe Thr
  65                  70                  75                  80
 Gln Ser Pro Gly Ser Arg Lys Lys Ala Thr Lys Ala Ser Ser Val Val
                  85                  90                  95    
 Val Ala Gln Cys Pro Ala Val Pro Trp Ala Pro Thr Thr Ala Ala Gly
             100                 105                 110        
 Val Ser His Ala Ser Cys Arg Val Val Gln Arg Glu Leu Phe Arg Ser
         115                 120                 125            
 Leu Asp Tyr Met Val Thr Val Asp Ser Asp Thr Leu Ala Ser Asp Ala
     130                 135                 140                
 Ala Arg Leu Thr Cys Arg His Ala Leu Gly Asn Gln Ser His Ala Asp
 145                 150                 155                 160
 Ser Leu Ile Asp Asn Thr Ser Gly Thr Val Gly His Thr Asp Asn Gln
                 165                 170                 175    
 Thr Asp Asn Thr Ser Gly Ile Val Phe Gln Thr Asn Ser Gln Thr Asp
             180                 185                 190        
 Asp Thr Ser Gly Thr Val Val Arg Ile
         195                 200    



      <210> 1569
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 1569
 Met Val Met Thr Phe Leu Gly Phe Leu Phe Ala Ser Ser Thr Gln Asp
   1               5                  10                  15    
 Leu Glu Leu Lys Glu Pro Ala Thr Val Lys His Gln Trp Glu His Arg
              20                  25                  30        
 Tyr Thr His Thr Pro Ile Pro Asn Arg Asn Ser Leu Leu Leu Ser Lys
          35                  40                  45            
 Gly Pro Arg Lys Ala Gln Gln Lys Lys Thr Glu Lys Ser Trp Arg Val
      50                  55                  60                
 Gly Ala Leu Leu Gln Ser Asn Thr Thr Pro Thr Leu Pro Ala Arg Ala
  65                  70                  75                  80
 Lys Arg Gln Glu Arg Ser Asn Leu Gly Val Arg Leu Tyr Ala Cys Cys
                  85                  90                  95    
 Gly Leu Leu Leu Cys Pro Ala Tyr Pro Gln His Phe Ala His Gly Tyr
             100                 105                 110        
 Val Asp Lys Ile Pro Gly Tyr Pro Gly Arg Ala Gly Thr Leu Thr Gly
         115                 120                 125            
 Leu His Pro Met Gln Val Cys Arg Cys Arg Arg
     130                 135                



      <210> 1570
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1570
 Met Thr Leu Ser Phe Phe Trp Pro Leu Pro Leu Val Leu Leu Val Leu
   1               5                  10                  15    
 Gly Ala Leu Leu Leu Ala Ile Ile Trp Thr Arg Leu Glu Glu Tyr Arg
              20                  25                  30        
 Trp Pro Ile Cys Thr Phe Ile Gly Met Thr Leu Val Met Asn Ala Asn
          35                  40                  45            
 Asp Cys Cys Cys Asp Gly Ala Cys Ser Ser Thr Pro Thr Leu Ser Glu
      50                  55                  60                
 Asn Val Ser Gly Thr Arg Tyr Ser Trp Lys Val Ser Gly Met Asp Cys
  65                  70                  75                  80
 Ala Ala Cys Ala Arg Lys Val Glu Asn Ala Val Arg Gln Leu Ala Gly
                  85                  90                  95    
 Val Asn Gln Val Gln Val Leu Phe Ala Thr Glu Lys Leu Val Val Asp
             100                 105                 110        
 Ala Asp Asn Asp Ile Arg Ala Gln Leu Asn Leu Arg Cys Lys Lys Gln
         115                 120                 125            
 Ala Ile Pro Cys Ala Met Asn Arg Pro Pro Lys Asn Arg Lys His His
     130                 135                 140                
 Ala
 145



      <210> 1571
      <211> 191
      <212> PRT
      <213> Homo sapiens


      <400> 1571
 Met Lys Ala Ser Trp Val His Leu Ala Leu Cys Leu Ala His Ser Ala
   1               5                  10                  15    
 Arg Gly Ala Asp Leu Arg Pro Gln Ser Arg Gly Cys Ser Gly Ala Ala
              20                  25                  30        
 Met Gly Glu Glu Pro Gly Ser Glu Ser Pro Pro Ser Ala Ala Gln Ser
          35                  40                  45            
 Arg Asp Pro Glu Leu Thr Glu Pro Pro Thr Leu Met Thr Arg Ser Ser
      50                  55                  60                
 Pro Cys Ala Asn Asp Ala Ser Ile Lys Leu Leu Asn Glu Gly Arg Ser
  65                  70                  75                  80
 Ser Pro Ala Cys Gly Ala Val Met Phe Ser Ala Ala Leu Met Ser Arg
                  85                  90                  95    
 Pro Gly Leu Phe Gln Arg Glu Arg Ser Ser Leu Leu Leu Thr Ser Ala
             100                 105                 110        
 Val Ala Val Phe Leu Gly Arg Ala Val Asn Arg Glu Tyr Leu Gly Ser
         115                 120                 125            
 Asp Gly Tyr Arg Arg Leu Ser Pro Trp Ala Ala Ser Arg Gly Pro Tyr
     130                 135                 140                
 Ala Ser Cys Ala Gly Arg Pro Gly Leu Cys Arg Glu Cys Val Gly Gly
 145                 150                 155                 160
 Arg Thr Val His Pro Gly Pro Pro Pro Val Lys Cys Ser Thr Leu Thr
                 165                 170                 175    
 Thr Ala Ala Pro Pro Arg Ser Pro Gly Gln Ile Leu Lys Leu Pro
             180                 185                 190    



      <210> 1572
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 1572
 Met Val Gln Leu Asp Ala Cys Leu Ser Trp Ala Leu Met Gly Trp Ile
   1               5                  10                  15    
 Cys Leu Leu Arg Leu Cys Ser Ala Gly Leu Trp Gly Ser Arg Ser Leu
              20                  25                  30        
 Gly Val Ser Trp Ala Ser Cys Ser Cys Thr Phe Ser Glu Asp Asp Lys
          35                  40                  45            
 Val Gln Ala Cys Lys Gly Glu Cys Gly Cys
      50                  55            



      <210> 1573
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 1573
 Met Val Ala Ser Leu Val Phe Ser Asp Leu Gly Phe Leu Ala Ser Gln
   1               5                  10                  15    
 Ile Pro Arg Asn Gly Ile Leu Gly His Val Val Gln Trp Gln Ala Phe
              20                  25                  30        
 Ser Pro Ile Gly Ser Gly Asn Gly Arg Leu Ala Gly Ser Gly Ala Gln
          35                  40                  45            
 Gln Thr Pro Tyr Arg Ile Arg Ser Asp Gly Ser Gln Arg Arg Val Cys
      50                  55                  60                
 Asp Gly Gly Lys Thr Ala Val Val Asp Ile Ala Glu Asp Lys Glu His
  65                  70                  75                  80
 Asn Leu Leu Glu Ala Leu Trp Ser Cys Pro Pro Pro Glu Lys Leu Ile
                  85                  90                  95    
 Gln Val Thr Leu Gly Gln Ala Cys Ala Leu Leu Ile Pro Leu Gln Leu
             100                 105                 110        
 Met Leu Ser
         115



      <210> 1574
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1574
 Met Pro Arg Gly Leu Leu Leu Val Leu Pro Ala Pro Ala Leu Gly Ser
   1               5                  10                  15    
 Arg Gln Leu Gly Pro Arg Cys Trp Gln Ala Arg Pro Gly Leu Ala Gly
              20                  25                  30        
 Ser Gly Gly Arg Cys Pro Cys Arg Glu Gly Pro Lys Pro Gly Ser Ala
          35                  40                  45            
 Leu Glu Asp Ala Pro Glu Gly Pro His Lys Gln Cys Pro Arg Leu Asp
      50                  55                  60                
 Trp Ser Cys Leu Ser Ile Val Pro Lys Gln Gly Ser Phe Ser His
  65                  70                  75                



      <210> 1575
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1575
 Met Pro Thr Phe Thr Leu Leu Phe Ser Ile Leu Leu Glu Val Leu Ala
   1               5                  10                  15    
 Arg Ala Val Arg Gln Glu Lys Glu Thr Lys Ala Ile Gln Ile Ser Asn
              20                  25                  30        
 Glu Glu Val Lys Leu Ser Leu Phe Ala His Asp Met Ile Thr Tyr Leu
          35                  40                  45            
 Glu Asn Ser Lys Asp Ser Ser Lys Lys Leu Leu Asp Leu Ile Lys Glu
      50                  55                  60                
 Phe Ser Lys Val Ser Gly Tyr Lys Ile Asn Val Gln Lys Ser Val Ala
  65                  70                  75                  80
 Leu Leu Tyr Thr Asn Ser Asn Gln Ala Glu Asn Gln Ile Lys Thr Ser
                  85                  90                  95    
 Thr Pro Phe Ile Thr Ala Ala Lys Asn Asn Ile Ile Lys Tyr Leu Gly
             100                 105                 110        
 Ile Tyr Leu Ile Lys Glu Val Lys Asp Leu Tyr Arg Glu Asn Tyr Gln
         115                 120                 125            
 Thr Leu Leu Asn Glu Ile Ile Asp Asp Thr Asn Lys
     130                 135                 140



      <210> 1576
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1576
 Met Trp Thr Ser Ala Pro Asn Ile Asp Ala Leu Leu Thr Lys Leu Ala
   1               5                  10                  15    
 Ala Leu Ala Leu Cys Thr Leu Leu Tyr Gln Leu Glu Asp Glu Ser Ala
              20                  25                  30        
 His Leu Asp Glu Met Pro Leu Met Met Ser Glu Glu Gly Phe Glu Asn
          35                  40                  45            
 Glu Glu Ser Asp Tyr His Thr Leu Pro Arg Ala Arg Ile Met Gln Arg
      50                  55                  60                
 Lys Arg Gly Leu Glu Trp Phe Val Cys Asp Gly Trp Lys Phe Leu Cys
  65                  70                  75                  80
 Thr Arg Phe Val Ile His Cys Tyr Leu Ile Ser Leu Tyr Ala Lys Val
                  85                  90                  95    
 Thr Tyr Lys Val Ser Phe
             100        



      <210> 1577
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 1577
 Met Thr Thr Ser Gly Arg His Gly Leu Trp Trp Ser Arg Leu Val Gly
   1               5                  10                  15    
 Val Thr Ala Cys Gly Cys Ser Gly Cys Cys Gly Ile Thr Ala Thr Leu
              20                  25                  30        
 Gly Ala Ala Arg Val Ser His Gly Gln Gly Thr Ala Ala Pro Asp Pro
          35                  40                  45            
 Ser Ala Trp Leu Ser Leu Leu Leu Ala Ser Arg Val Pro Leu Arg Val
      50                  55                  60                
 Val Gly Gly Leu Gln Gly Ser Val Gly Gly Trp Lys Met Asn Trp Ser
  65                  70                  75                  80
 Met Thr Pro Lys Ala Leu Cys Gln Val Leu Thr Ser His Tyr Leu Ser
                  85                  90                  95    
 Lys Gln Pro Leu Glu Ile Lys Ile Ile Ser Thr Ile Leu Pro Met Lys
             100                 105                 110        
 Lys Leu Lys Phe Asn Lys Thr Ala Phe Glu Gly Tyr Glu Glu Asn Pro
         115                 120                 125            
 Asp Phe Pro Ala Tyr Thr Gly Ser His Arg Ser Gln Glu Leu Leu Arg
     130                 135                 140                
 Gln Gln Thr Gln Pro Ser Pro Leu Gly Phe Ala Asn Thr Gly Ser Leu
 145                 150                 155                 160
 Cys Ser Ser Met Gly Leu Trp Lys Gly Gly Met Pro Pro Pro Ala Cys
                 165                 170                 175    
 Met Pro Gly Val Arg Gly Ser Pro Arg Val Cys Arg Gly Glu Gly Tyr
             180                 185                 190        
 Lys Pro Lys Gln Ala Ile Gly Val Ile Leu Phe Leu Arg Lys Val Ser
         195                 200                 205            
 Arg Leu Lys Asp Phe Trp Phe Glu Gln His Pro Leu Trp Met His Gln
     210                 215                 220                
 Ala Lys Val Thr Thr Phe Asp Gln Pro Ser Glu Lys Ala Phe Ala Gly
 225                 230                 235                 240
 Pro Arg Ser Glu Glu Leu Ala Gly Thr Gly Ser Leu Leu Pro Ala Gly
                 245                 250                 255    
 Leu His Cys Arg Gly Pro Val Gly Arg Leu His Arg Gln Pro Leu Ser
             260                 265                 270        
 Val Ala Arg Gln Ala Val Leu Val Thr Arg Ala Tyr Arg Leu Trp Phe
         275                 280                 285            
 Arg Thr Ala Glu Gly Glu Arg Arg Val Gly Gln Gly Thr Pro Thr Arg
     290                 295                 300                
 Arg Cys Ser Asp Gln Ser Glu Asn Val Arg Gln Leu Pro His Arg Asp
 305                 310                 315                 320
 Leu His Arg Glu Gly Val Glu Gly Thr Ser Lys Ser Asp Gly Thr Arg
                 325                 330                 335    
 Asp Pro Arg Gly Arg Gly Ser Arg Arg Pro Gln Gln Ala Gln Arg
             340                 345                 350    



      <210> 1578
      <211> 242
      <212> PRT
      <213> Homo sapiens


      <400> 1578
 Met Lys Ile Met Ile Phe Thr Met Ala Cys Glu Ala Leu Leu Tyr Asp
   1               5                  10                  15    
 Leu Ala Leu Pro Cys Leu Ser Ser Phe Ile Pro Thr Leu Met Pro Thr
              20                  25                  30        
 Thr Leu Met Ser Phe Gln Gly Leu Glu Tyr Ala Lys Leu Phe Pro Ala
          35                  40                  45            
 Ser Thr Ser Phe Tyr Val Leu Phe Pro Leu Ser Arg Glu Tyr Leu Gln
      50                  55                  60                
 Tyr Pro Asp Phe Leu Ile Leu Tyr Leu Val Val Phe Tyr Val Ser Phe
  65                  70                  75                  80
 Asn Ser Gln Phe Lys Tyr His Leu Leu Lys Lys Ser Ser Asp Leu Pro
                  85                  90                  95    
 Gly Lys Lys Asn Leu Leu Thr Leu Asp Ile Glu Gln Glu Thr Ile His
             100                 105                 110        
 Val Arg Glu Val Lys Asp Ile Pro Asn Val Leu Val Gly Thr Ala Phe
         115                 120                 125            
 Asn Val Asp Asp Gly Asn Gly Gly Phe Val Val His Trp Leu Asn Asn
     130                 135                 140                
 Lys Glu Phe His Phe Thr Ser Ser Thr Glu Val Phe Met His Gln Leu
 145                 150                 155                 160
 Arg Lys Leu Ser Asp Lys Gln Val Asp His Glu Asn Asp Asp Ala Asp
                 165                 170                 175    
 Arg Glu Asp Glu Glu His Ser Gln Glu Asp Arg Glu Arg Gly Leu His
             180                 185                 190        
 Met Lys Leu Asp His Glu Asn Leu Arg Gln Val Gln Asp His Gln Asn
         195                 200                 205            
 Met Lys Met Glu Lys Glu Lys Glu Val Leu Glu Leu Thr His Asp Leu
     210                 215                 220                
 Val Tyr Gln Cys His Cys Leu Arg Phe Cys Leu Ile Gly Arg Leu Lys
 225                 230                 235                 240
 Cys Cys
        



      <210> 1579
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1579
 Met Ser Ile Leu Arg Thr Leu Leu Ala Ala Phe Leu Arg Leu Gln Leu
   1               5                  10                  15    
 Arg Pro Trp Leu Lys Asp Ala Gln Ser Phe Arg Leu His Gly Lys Thr
              20                  25                  30        
 Ser Ser Thr Ala Met His Gln Gly Gln Gly Glu Val Leu Leu Gln His
          35                  40                  45            
 Arg Ser Ala Asp Leu Arg Gly Leu Ile Val Ala Arg Met Leu Leu Val
      50                  55                  60                
 Ser Lys Pro Gln Arg Gly Asn His Arg Thr Thr Ser Trp Phe Ser Val
  65                  70                  75                  80
 Phe Gln Cys Ile Gln Leu Leu Ile Tyr Leu Ala Lys Lys Thr Tyr Leu
                  85                  90                  95    
 Arg Arg Ala Glu Gln Arg Pro Glu Leu Leu Glu Asp Ser Ala Trp Thr
             100                 105                 110        
 Trp Ser Ser Gln Arg Leu Ala Thr Trp Lys Arg Ile Gln Arg Thr Gly
         115                 120                 125            
 Gln Asn Thr Trp Ala Ser Glu Gly Ile Val His Leu Pro Ile Tyr Cys
     130                 135                 140                
 Pro
 145



      <210> 1580
      <211> 326
      <212> PRT
      <213> Homo sapiens


      <400> 1580
 Met Ser Phe Phe Leu Val Thr Val Asn Ile Leu Leu His Ser Ala Glu
   1               5                  10                  15    
 Glu Leu Arg Ala His Pro Phe Thr Asp Val Thr Leu Ser Cys His Phe
              20                  25                  30        
 Ser Phe Val Lys Gly Thr Glu Asn Leu Glu Phe Ser Trp Glu Arg Glu
          35                  40                  45            
 Asp Ile Lys Gln Ala Tyr Glu Val Glu Asp Asn Lys Glu Tyr Tyr Leu
      50                  55                  60                
 Leu Phe Lys Tyr Leu Asp Phe Phe Glu Val Phe Ser Lys Leu Val Tyr
  65                  70                  75                  80
 Gln Phe His Asn Asn Thr Glu Gln Leu Glu Asp Gln Asn Ser Leu Tyr
                  85                  90                  95    
 Glu Gly Arg Val Ser Val Asp Gln Ala Glu Ile Ser Glu Gly Thr Leu
             100                 105                 110        
 Ser Leu Leu Leu Arg Asn Val Asp Phe Met Asp Glu Ala Ile Tyr Lys
         115                 120                 125            
 Cys Ser Ala Ile Thr Pro Asp Gly Arg Gly Glu Ser Thr Ile Lys Leu
     130                 135                 140                
 Ile Val Glu Glu Arg Asp Leu Ser Asn His Ser Ile Val Glu Ile Leu
 145                 150                 155                 160
 Glu Glu Gln Met Asn Gly Phe Tyr Arg Val Phe Ser Ile Leu Lys Tyr
                 165                 170                 175    
 Pro Val Lys Leu Asn Glu Lys Tyr Leu Cys His Ile Thr Glu Thr Asp
             180                 185                 190        
 Val Asn Asn Gln Leu Phe Arg Ile Ile His Lys Tyr Pro Ser Pro Val
         195                 200                 205            
 Val Pro Thr Arg Lys Pro Trp Asp Thr Tyr Pro Ile Pro Trp Val Phe
     210                 215                 220                
 Pro Tyr Pro Ser Leu His Leu Leu Thr His Phe Leu Ile Glu Thr Leu
 225                 230                 235                 240
 Leu Phe Lys Tyr Leu Asn Ser Gly Ser Leu Asn Asn Gly Pro Pro Lys
                 245                 250                 255    
 Tyr Val Tyr Ile Leu Ile Leu Glu Pro Val Asn Val Thr Leu Leu Asp
             260                 265                 270        
 Glu Lys Lys Val Phe Ala Glu His Leu Leu Glu Val Gly Ser Asn Gln
         275                 280                 285            
 Pro Ser Ser His Ser Val Thr Lys His Ile Tyr Ala His Thr Glu Ser
     290                 295                 300                
 Ser Gly Asn Ser Thr Pro Pro Pro Ala Lys Thr Gln Asn Leu Thr Val
 305                 310                 315                 320
 Gly Leu Leu Ala Ser Tyr
                 325    



      <210> 1581
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1581
 Met Val Val Val Glu Gly Met Phe Val Ile Val Ala Gln Leu Lys Gly
   1               5                  10                  15    
 Phe Gln Gly Gly Cys Lys Ile Phe Ile Ile Val Glu Leu Arg Ile Leu
              20                  25                  30        
 Phe Thr Leu Ala Phe Pro Ile Pro Phe His Ile Ser Asp Val Lys Glu
          35                  40                  45            
 Ala Met Leu Ser Val Ile Leu Ser Met Ser Cys Ser Ala Ile Met Ser
      50                  55                  60                
 Pro Gln Pro Val Asn Glu Ser Lys Leu Phe Arg Asp Val Thr Ser Pro
  65                  70                  75                  80
 Asn Lys Arg Leu Asn Arg Phe Glu Trp Pro Lys Asn Glu Lys Pro Ala
                  85                  90                  95    
 Asn Val Asp Lys Asp Ala Glu Phe Glu Leu Phe Glu Glu Asn Asp Leu
             100                 105                 110        
 Ser Asp Asp Leu Glu Leu Glu
         115                



      <210> 1582
      <211> 39
      <212> PRT
      <213> Homo sapiens


      <400> 1582
 Met Lys Gly Gly Gly Ser Leu Ile Ala Thr Ala Leu Leu Leu Arg Thr
   1               5                  10                  15    
 Gly Asn Leu Leu Asp Pro Val Asp Asn Asp Lys Cys Ile Gly Gln Ser
              20                  25                  30        
 Asp Phe His Trp Met Ile Gly
          35                



      <210> 1583
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1583
 Met Ala Gly Ala Cys Trp Leu Met Ala Phe Gln Tyr Trp Val Val Lys
   1               5                  10                  15    
 Leu Leu Val Val Lys Ser Ala Tyr Gly Leu Leu Lys Ala Leu Ala Asn
              20                  25                  30        
 Gly Ile Gly Ile Ser Glu Val Ala Lys Thr Trp Asn Pro Gly Glu Lys
          35                  40                  45            
 Lys Arg Leu Pro Ala Met Ser Pro Ser Glu Ser Ile Leu Pro Ser Val
      50                  55                  60                
 Ser Thr Phe Ala Ser Pro Tyr Arg Lys Arg Arg Leu Gln Glu Arg
  65                  70                  75                



      <210> 1584
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1584
 Met Leu Val Val Leu Ala Leu Thr Leu Phe Ser Phe Thr Val Val Val
   1               5                  10                  15    
 Leu Asn Ser Ile Arg Ala Met Val Pro Ser Glu Arg Ile Phe Lys Ala
              20                  25                  30        
 Lys Asp Leu Leu Ser Arg Lys Ile His Ile His Ile Tyr Asp Lys Asn
          35                  40                  45            
 Ile Ala Tyr Glu Ser Ala Val Pro Ile Met Pro Val Ile Pro Gln Thr
      50                  55                  60                
 Gly Ser Pro Thr Tyr Thr Ser Ser Ala Ala Leu Pro Gln Cys Leu Thr
  65                  70                  75                  80
 Pro Gly Asn Thr Ile His Ser Val Ala Ile Val Asn Gly Ser Ser Trp
                  85                  90                  95    
 Ser Ser Ala Leu Arg Ser Gln Cys Asp His Arg Leu His Thr Cys Ser
             100                 105                 110        
 Phe Thr Leu Val Pro Gln Arg His Pro His Thr Gln Leu Ile
         115                 120                 125    



      <210> 1585
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 1585
 Met Ile Ser Val Gln Leu Phe Val Phe Pro Pro Leu Gly Gly Val Met
   1               5                  10                  15    
 Val Leu Gln Cys Ser Leu Phe Ala Asn Thr Tyr Ile Lys Ser Trp Glu
              20                  25                  30        
 Asn Gly Asn Thr Arg Phe Arg Glu Leu Pro Leu Ala Ser Leu Cys Thr
          35                  40                  45            
 Thr Ser Leu Ser Glu Thr Glu Ser Gly Pro Pro Ala Gln Glu His Arg
      50                  55                  60                
 Asp Gln Pro Gly Ser Arg Pro Trp Ala Ala Ala Ala Thr Gln Gly Arg
  65                  70                  75                  80
 Glu Gln Leu Glu Ala Leu Val Phe Ala His Arg Ala Lys Arg Asn Ser
                  85                  90                  95    
 Ser Arg Leu Cys Ser Ser Pro Gly Ser Ala Leu Gly Ile Ser His Gly
             100                 105                 110        
 Leu Ala Leu Cys Gly Lys Pro Glu Arg Arg Leu Leu Trp Ala Ser Pro
         115                 120                 125            
 Pro Pro Leu Pro Glu Pro Glu Pro Ala Leu Ala Cys Ile Gln Ala Ser
     130                 135                 140                
 Tyr Phe Arg Leu Thr Ser Gly Pro Val Gly Gln Met Leu Ala Ala Gly
 145                 150                 155                 160
 Glu Cys Leu His Ala Lys Arg Pro Lys Ser Arg Ala Cys Pro Val Gly
                 165                 170                 175    
 Leu Leu Arg Leu Leu Thr Arg Val Ser Gly Arg Ala Asp Ser Ala Ser
             180                 185                 190        
 Pro Leu Phe Arg Gly Ser
         195            



      <210> 1586
      <211> 96
      <212> PRT
      <213> Homo sapiens


      <400> 1586
 Met Gly Trp Pro Arg Asp Arg Glu Leu Leu Ile Lys Ile Ser Val Lys
   1               5                  10                  15    
 Ala Ala Cys Ala Ala Leu Val Leu Gly Gly Leu Trp Cys Arg Val Cys
              20                  25                  30        
 Cys Gly Val Pro Arg Arg Arg Cys Cys Phe Thr Gly Gly Ser Ile Leu
          35                  40                  45            
 Val Leu Ala Gly Ser Glu Glu Gly Ser Glu Glu Asn Ser Gly Gly Arg
      50                  55                  60                
 Met Lys Glu Gly Thr Val Ser Pro Ser Pro Ser Ala Leu Glu Ala Ala
  65                  70                  75                  80
 Thr Ser Ala Phe Gln Leu Gly Trp Ser Tyr Arg Gly Asp Gly Val Gly
                  85                  90                  95    





      <210> 1587
      <211> 229
      <212> PRT
      <213> Homo sapiens


      <400> 1587
 Met Val Ala Met Ala Ser Ser Trp Met Ser Glu Trp Ala Leu Ala Thr
   1               5                  10                  15    
 Val Cys Arg Arg Thr Leu Pro His Phe Ser Ser Leu Leu Phe Cys Gln
              20                  25                  30        
 Ser Thr Pro Leu Pro Ser Phe Pro Val Thr Tyr Thr Ile Ser Pro Val
          35                  40                  45            
 Ser Ala Phe His Ser Ala His Ile Ser Asp Thr Leu Lys Thr Gln Glu
      50                  55                  60                
 Lys Asp Thr Cys Ser Ile Phe Val Gly Asn Glu Asn Ser Ser Asp Asp
  65                  70                  75                  80
 Phe Arg Arg Ser Gln Pro Thr Gly Met Ser Gln Gly Lys Val Ser Pro
                  85                  90                  95    
 Val Ile Leu Gly Gly Pro Arg Gln Gln Met Asp Lys Arg Ser His Ser
             100                 105                 110        
 Gly Cys Ser Gln Ala Lys Ser Trp Ser Gln Arg Gly Ala Ala Leu Glu
         115                 120                 125            
 Glu Glu Thr Thr Thr Pro Pro Val Pro Thr Phe Asn Lys His Tyr Tyr
     130                 135                 140                
 Leu Tyr Met Gln Asn Ala Ala Leu Ala Ala Glu Lys Lys Arg Asn Ile
 145                 150                 155                 160
 Asn Leu Met Trp Gly Pro Gln Gln Gly Leu Glu Pro Ser Thr Leu Val
                 165                 170                 175    
 Tyr Leu His Ala Cys Ser Leu Ala Arg Pro His Arg Ser Asp Arg His
             180                 185                 190        
 Asn Lys Ala Ile Val Thr Pro Ala His Gln Ala Arg Gly Gly Cys Pro
         195                 200                 205            
 Ser Pro Gly Trp His Leu Lys Ala Val Asn Ala Gly Leu Ser Arg Arg
     210                 215                 220                
 Glu Ala Thr Val Ser
 225                



      <210> 1588
      <211> 100
      <212> PRT
      <213> Homo sapiens


      <400> 1588
 Met Lys Val Leu Arg Phe Thr Leu Glu Leu Val Gly Ala Met Gly Cys
   1               5                  10                  15    
 Thr Ala Ala Gly Ser Asp Gln Arg Gln Leu Cys Val Leu Glu Gly Phe
              20                  25                  30        
 Leu His Gln Thr Gly Leu Ser Trp Phe Ala Lys Asp Arg Lys Pro Asn
          35                  40                  45            
 Ser Lys Trp Leu Lys Ser Lys Thr Glu Phe Thr Gly Thr Phe Asp Arg
      50                  55                  60                
 Met Val Cys Gly Val Gly Trp Pro Gln Ala Ile Val His Asn Gln Pro
  65                  70                  75                  80
 Leu Gln Asn Ala Leu Leu Ser Ser Pro Trp Ala Val Phe Val Ser Thr
                  85                  90                  95    
 Phe Leu Ile Tyr
             100



      <210> 1589
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 1589
 Met Lys Lys Val Leu Ala Met Phe Leu Phe Pro Val Leu Gly Leu Ile
   1               5                  10                  15    
 Asp Ser Arg Ser Asn Asp Leu Leu His Gln Ile Leu Arg Val Gly Ala
              20                  25                  30        
 Met Asp Ala Val Arg Ile Leu His Cys Thr Val Ser His Phe Arg Met
          35                  40                  45            
 Pro Ser Ile Leu Phe Pro Ser Asp Pro Leu Met Pro His Ile Gln Val
      50                  55                  60                
 Gln Lys Lys His Leu Glu Glu Trp Arg Lys Val Glu Glu Val Ser Leu
  65                  70                  75                  80
 Asn Ser Leu Gly Asp His Leu Glu Ala Gly Asn Thr Val Val
                  85                  90                



      <210> 1590
      <211> 84
      <212> PRT
      <213> Homo sapiens


      <400> 1590
 Met Ser Ala Leu Thr Asn Met Thr Lys Glu Pro Trp Asn Thr Phe Ile
   1               5                  10                  15    
 Leu Ile Thr Tyr Leu Leu Pro Tyr Met Leu Leu Ser Asp Arg Thr His
              20                  25                  30        
 Leu Gln Ser Lys Phe Phe Thr Lys Ala Ser Gly Ile Asn Gln Ser Glu
          35                  40                  45            
 Ser Trp Ala Val Gln Glu Gly Pro Gly Asp Ile Pro Ala Leu Pro Arg
      50                  55                  60                
 His Asp Tyr Gln Asn Thr Ile Asp Gly Thr Val Phe Phe His Gln Glu
  65                  70                  75                  80
 Ala His Asp Val
                



      <210> 1591
      <211> 152
      <212> PRT
      <213> Homo sapiens


      <400> 1591
 Met Pro Arg Leu Gly Met Leu Trp Trp Leu Leu Phe Val Leu Met Leu
   1               5                  10                  15    
 Leu Leu Phe Thr Leu Asp Leu Cys Thr Ala Phe Asp Arg Tyr Lys Gly
              20                  25                  30        
 Gln Thr Leu Ala Pro Phe Pro Gln Cys Leu Gln Glu Pro Ala Gly Gly
          35                  40                  45            
 Ala Glu Pro Glu Gly Leu Lys Glu Gly Glu Thr Arg Met Ser Ala Gly
      50                  55                  60                
 Leu Pro Arg Lys Thr Tyr Pro Gly Val Leu Ser Leu Lys Ala Gln Ser
  65                  70                  75                  80
 Ser Glu Leu Val Trp Lys Trp Pro Leu Thr Cys Gly Leu Asp Thr Trp
                  85                  90                  95    
 Asp Phe Asp Thr Trp Lys Leu Leu Lys Arg Gln Met Ala Glu Asp Phe
             100                 105                 110        
 Met Glu Ala Lys Lys Lys Pro Thr Pro Asn Ser Val Ala Pro Gly Thr
         115                 120                 125            
 Met Leu Gly Thr His Phe Gly Asp Ser Ser Thr Ser Ala Ala Ser Leu
     130                 135                 140                
 Cys Tyr Glu Asp Leu Leu Ala Ala
 145                 150        



      <210> 1592
      <211> 314
      <212> PRT
      <213> Homo sapiens


      <400> 1592
 Met Leu Ser Phe Val Pro Ser Leu Ile Leu Cys Leu Leu Cys Pro Ser
   1               5                  10                  15    
 Met Glu Leu Gln Gly Ser Ser Met Gly Thr Ser Arg Pro Leu Met Ser
              20                  25                  30        
 Ala Ser Ser Glu Ala Ser Gly Gly Val Ser Met Phe Val Trp Arg Asn
          35                  40                  45            
 Val Glu Pro Cys Ser Val Ala Val Phe Ser Trp Tyr Ser Val Pro Phe
      50                  55                  60                
 Leu Thr Pro Pro Cys Ser Arg Val Arg Pro Ser Asn Leu Pro Val Thr
  65                  70                  75                  80
 Gln Trp Pro Pro Thr Arg Ala Lys Asn Leu Pro Ser Arg Gln Leu Leu
                  85                  90                  95    
 Leu Thr Ser Val His Gln Ala Gln Ser Leu Ser Ala Leu Cys Lys Glu
             100                 105                 110        
 Gln Asp Ser Ser Ser Glu Lys Asp Gly Arg Ser Pro Asn Lys Trp Asp
         115                 120                 125            
 Lys Asp His Ile Trp Trp Pro Met Ser Gly Gly His Asp Leu Gln Gln
     130                 135                 140                
 Ala Ala Pro Gly Pro Gly Arg Ala His Gln Gly His Pro Tyr Gln Asp
 145                 150                 155                 160
 Asn Trp Thr Ile Ser Gln Ile Leu Ser Glu Arg Trp Tyr Thr Leu Gly
                 165                 170                 175    
 Pro Asn Glu Met Gln Lys Tyr His Asp Leu Ala Phe Gln His Met Ala
             180                 185                 190        
 Gly Glu Asp Thr Ala Ser Asp Glu Glu His Met Val Ile His Glu Glu
         195                 200                 205            
 Glu Gly Val Met Met Ser Leu Leu Met Thr Ala Leu Ala Pro Leu Thr
     210                 215                 220                
 Leu Ile Ser Ser Ser Arg Ile Phe Gly Lys Val Tyr Gly Pro Thr Pro
 225                 230                 235                 240
 Ser Ser Ser Tyr Thr Tyr Ser Asp Ala Ser Ser Ser Thr Leu Ala Pro
                 245                 250                 255    
 Thr Ser Phe Leu Leu Gly Pro Gly Ala Phe Lys Ala Gln Glu Ser Gly
             260                 265                 270        
 Glu Ala Glu Asp Gly Leu Arg Lys Leu Glu Thr Glu Lys Ala Leu Ser
         275                 280                 285            
 Ser Ser Leu His Ala Pro Trp Thr Ser Ala Gly Pro Asp His Ala Ala
     290                 295                 300                
 Leu Pro Gly Pro Leu Leu Leu Pro Val His
 305                 310                



      <210> 1593
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 1593
 Met Ser Ala Tyr Cys Phe Gln Phe Thr Ser Ser Gln Phe Tyr Tyr Gln
   1               5                  10                  15    
 Lys Arg Lys Leu Leu Phe Phe Leu Ala Ala Leu Gln Leu Ile Leu Ala
              20                  25                  30        
 Lys Ile Ile Ile Glu Ser Ser Val Ser His Phe Thr Ile Gln Leu Cys
          35                  40                  45            
 Gln Leu Leu Pro Asn Asp Gly Ile Tyr Ala Ser Ser Leu Phe Ile Val
      50                  55                  60                
 Ala Gly Lys Leu Arg Pro Pro Arg Thr Arg Asn Asn Lys Ala Arg Lys
  65                  70                  75                  80
 Thr Glu Ser Glu Pro Arg Gly Leu Leu Ala Thr Gly Arg Gly Gly Ser
                  85                  90                  95    
 Ser Met Glu Thr Gly Glu Arg Ala Arg Leu Ile Leu Ile Leu Val Leu
             100                 105                 110        
 Gln Leu Leu Leu Arg Ile Arg Arg Asn Arg Gln Gln Arg Cys Arg Arg
         115                 120                 125            
 Val Leu Ser His Arg Ser Leu Phe Pro Arg
     130                 135            



      <210> 1594
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 1594
 Met Pro Ser Gly Lys Ile Leu Cys Ile His Cys Leu Gly Leu Leu Lys
   1               5                  10                  15    
 Pro Leu Leu Cys Ala Ala Leu Pro Pro Thr Gly Leu Leu Asn Gly Phe
              20                  25                  30        
 Pro Leu Arg Glu Pro Leu Gln Pro Val Val Ser Arg Gln Ala Leu Gly
          35                  40                  45            
 His Gln Ala Gly Glu Ser Arg Gly His Thr Gln Arg Cys Lys Val Thr
      50                  55                  60                
 Arg Leu Ser Ser Trp Gln Val Leu Val Gly Ala Ala Val Pro Cys Ser
  65                  70                  75                  80
 Gly Ala Arg Asp Arg Val Pro Val Pro Arg His Val Pro Gln Ala Cys
                  85                  90                  95    
 Leu Gln Gly Arg Val Gln Thr Gly Arg Leu Asp Trp Arg Gly His Ala
             100                 105                 110        
 Cys Ser Ala Ser Pro Asn Ala Val Pro Thr Val Gly Gly Thr Val Thr
         115                 120                 125            
 Gly Leu Gly Gly Val Gln Gly Gly Gly Asp Glu
     130                 135                



      <210> 1595
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1595
 Met Val Ser Gly Gln Ala Gly Arg Ala Ser Gly Gly Ala Asp Ile Thr
   1               5                  10                  15    
 Pro Phe Val Phe Lys Pro Phe Leu Val Phe Leu Val Ser Ser Leu Ser
              20                  25                  30        
 Leu Gly Ser Thr Ser Ser Glu Gly Leu Glu Ala Val Ser Leu Leu Leu
          35                  40                  45            
 Gly Pro Gly Ser Ser Glu Leu Tyr Ser Pro Pro Lys Asp Arg Lys Arg
      50                  55                  60                
 Thr Ser Thr Phe Cys Leu Asn Val Cys Arg Glu Asn Val Met Lys Asp
  65                  70                  75                  80
 Val Ser Ile Ala Ile Val Leu Phe Gln Leu Ala Val Ala Gly Gly Pro
                  85                  90                  95    
 His Glu Ser Pro Val Cys Tyr Ala Asn Gly
             100                 105    



      <210> 1596
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 1596
 Met Glu Trp Arg Leu Leu Ser Ala Phe Val Ala Cys Val Cys Gly Lys
   1               5                  10                  15    
 Ala Leu Cys Asp Val Leu Ser Pro Val Asp Ser Val His Ser Phe Ser
              20                  25                  30        
 Ala Leu Phe Val Leu Ala Leu Thr Gln Asp Lys Lys Asn Trp Gly Pro
          35                  40                  45            
 Glu Lys Leu Gly His Ala Ala Val Arg Val Lys Val Cys Thr Thr Pro
      50                  55                  60                
 Lys Pro Thr Cys Pro Tyr Ala Asp His Val Leu Pro Leu Thr Leu Asn
  65                  70                  75                  80
 Gly Phe Val Pro Leu Pro Ala Asn Ala Leu
                  85                  90



      <210> 1597
      <211> 201
      <212> PRT
      <213> Homo sapiens


      <400> 1597
 Met Ile Ser Val Thr Leu Ser Phe Ile Leu Met Phe Gly Asn Ser Met
   1               5                  10                  15    
 Tyr Leu Ser Ser Ser Tyr Ser Ser Ser Leu Leu Met Thr Trp Ile Lys
              20                  25                  30        
 Leu His Lys Ala Asn Val Leu Cys Ala Asp Leu Glu Leu Ala Asn Thr
          35                  40                  45            
 Asp Glu Tyr Asn Val Pro Phe Val Ser Ala Gly Ile Asp Ser Arg Thr
      50                  55                  60                
 Pro Pro Thr Pro Val Asp Thr Lys Ile Cys Arg Cys Ser Ser Phe Leu
  65                  70                  75                  80
 Tyr Lys Met Ala Ile Ile Leu Lys Arg Asn Glu Ile Gln Lys Leu Gly
                  85                  90                  95    
 Val Ser Lys Leu Asn Phe Trp Glu Ser Lys Asp Val Ser Gly Lys Ser
             100                 105                 110        
 Lys Asn Trp Gln Lys Thr Leu Arg Lys Arg Val Gln Gly Asn Ala Leu
         115                 120                 125            
 His Ala Val Gly Leu Val Ser Thr Ile Pro Ser Lys Lys Ala Ala His
     130                 135                 140                
 Ala Gly Ser Ser Ser Arg Asp Leu Thr Asp Ala Leu Leu Gly Leu Gly
 145                 150                 155                 160
 Ser Pro Gly Lys Ser Pro Leu Leu Phe Thr Asp Leu Leu Ala His Asn
                 165                 170                 175    
 Pro Gly Val Ser Gln Pro Pro Pro His Gly Asn Arg Thr Trp Glu Val
             180                 185                 190        
 His Ser Ser Tyr Ile Gly Ser Met Ile
         195                 200    



      <210> 1598
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1598
 Met Ala Ala Leu Ala Met Ala Ala Leu Ala Met Ala Thr Leu Thr Met
   1               5                  10                  15    
 Ala Ala Leu Met Met Ala Leu Val His Ala Ala Pro Ala Val His Ala
              20                  25                  30        
 Ala Pro Ala Ile His Gln Leu Pro Gly Gly Leu Pro Arg Ala Ile His
          35                  40                  45            
 Thr Ser Met Ser Val Ser Ile Ser Ser Ser Phe Ser Pro Thr Ser Asp
      50                  55                  60                
 Ala Pro Ser Ala Ala Leu Arg Val Pro Gln Ser Phe Ser Arg Lys Pro
  65                  70                  75                  80
 Thr Leu Cys Leu Ala Pro Gly Tyr Pro Met Pro Cys Ala Leu Pro Pro
                  85                  90                  95    
 Pro Asp Ser Ser Glu Gly Gly Phe Arg Gly Ile Phe Ala Ser Ser Glu
             100                 105                 110        
 Gly Gly Phe Arg Gly Ile Phe Ala Ser Ser Glu Gly Gly Phe Arg Gly
         115                 120                 125            
 Ile Phe Ala Ser Ser Glu Asp Ser Ser Ser Gln Ser Ser Pro Glu Arg
     130                 135                 140                
 Leu Leu Tyr Thr Thr Phe Leu Trp Ser Ser Gly Gly Pro Ala Ile Arg
 145                 150                 155                 160
 Ser Pro Leu Lys Asp Ala Cys Val Ala Ser Ser Thr Trp
                 165                 170            



      <210> 1599
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1599
 Met Gly Ser Ala Pro Ala Thr Leu Thr Leu Pro Phe Pro Leu Leu Leu
   1               5                  10                  15    
 Ser Ser Ser Ser Phe Pro Thr Thr Ser Ser Ala Thr His Asn Lys Thr
              20                  25                  30        
 Leu Thr Glu Tyr Pro Ser Arg Thr Leu Leu Ser Ile Arg Thr Ser Arg
          35                  40                  45            
 Lys Asn His Gly Leu Cys Thr Met Gly Thr Gln Asn Lys Glu Lys Lys
      50                  55                  60                
 Glu Lys Tyr Leu Gly Met Leu Tyr Thr Asn Asn Met Pro Glu Ala Asn
  65                  70                  75                  80
 Arg Ser Thr Asn Cys Met Ser Pro Gly Asp Leu Asp Cys Thr Asp Thr
                  85                  90                  95    
 Ser Trp Ile Leu Pro Ser Arg Pro Asp Ala Gly Gly Arg Phe Pro Ile
             100                 105                 110        
 Arg Thr Pro Pro Cys Val Leu Val Val His Lys Pro Ser Arg His Cys
         115                 120                 125            
 Arg Glu Leu Lys Ser His Gly Phe Val His Ser Val Asp Thr Asp Ala
     130                 135                 140                
 His Pro Val Pro Gly Thr Val Val Asp Ile Glu Lys Thr Ala Asn Ile
 145                 150                 155                 160
 Gln Thr Thr Ser Cys Tyr Cys Ala His Cys His Gly Gly
                 165                 170            



      <210> 1600
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1600
 Met Arg Val Gly Ala Cys Ala Leu Cys Pro Leu Gly Cys Gln Ser Leu
   1               5                  10                  15    
 Leu Gly His Pro Val Gln Gly Trp Ser Gly Gly Gly Leu Leu Lys Glu
              20                  25                  30        
 Val Ala Leu Leu Ser Pro Ala Leu Phe Leu Thr Leu Thr Asp Trp Pro
          35                  40                  45            
 Asn Ser Thr Gln Thr Asn Ser Met Cys Gly Arg Val Pro Val Tyr Lys
      50                  55                  60                
 Lys Glu Met Ala Thr Ser Arg Asp Thr Val Lys Thr Thr Ala Ile His
  65                  70                  75                  80
 Val Ser
        



      <210> 1601
      <211> 264
      <212> PRT
      <213> Homo sapiens


      <400> 1601
 Met Pro His Ser Leu Gln Thr Leu Ile Leu Phe Gly Leu Ser Leu Ala
   1               5                  10                  15    
 Asn Arg Asn Phe Ile Ile Gly Thr Ser Asp Ala Ala Val Tyr His Leu
              20                  25                  30        
 Thr Thr Asp Gly Thr Lys Leu Glu Lys Leu Phe Val Glu Pro Lys Asp
          35                  40                  45            
 Ala Ile Cys Ala Ile Ser Cys His Pro Tyr Gln Pro Leu Ile Ala Ile
      50                  55                  60                
 Gly Ser Ile Cys Gly Met Ile Lys Val Trp Asn Tyr Glu Asn Lys Gln
  65                  70                  75                  80
 Tyr Leu Phe Ser Arg Val Phe Glu Lys Gly Leu Gly Val Gln Ser Leu
                  85                  90                  95    
 Thr Tyr Asn Pro Glu Gly Ala Leu Leu Gly Ala Gly Phe Thr Glu Gly
             100                 105                 110        
 Thr Val Tyr Ile Leu Asp Ala Met Ser Leu Glu Asn Glu Ser Pro Glu
         115                 120                 125            
 Pro Phe Lys Tyr Ser Arg Thr Ser Val Thr His Ile Ser Phe Ser His
     130                 135                 140                
 Asp Ser Gln Tyr Met Ala Thr Ala Asp Arg Ser Phe Thr Val Ala Val
 145                 150                 155                 160
 Tyr Met Leu Val Val Arg Asn Gly Gln Arg Val Trp Glu Tyr Leu Ala
                 165                 170                 175    
 Arg Leu Arg Ser His Arg Lys Ser Ile Arg Ser Leu Leu Phe Gly Val
             180                 185                 190        
 Tyr Leu Asp Ser Asn Glu Pro Arg Leu Leu Ser Leu Gly Thr Asp Arg
         195                 200                 205            
 Leu Leu Val Ser Cys Leu Val Phe Val Asp Leu Val Ala Lys Thr Val
     210                 215                 220                
 Ser His Ser Cys Asp Ile Pro Gly Ile Leu His Arg Ala Arg Pro Thr
 225                 230                 235                 240
 Val Arg Val Phe Val Gly Glu Asn Glu Cys Thr Val Lys Asp His Lys
                 245                 250                 255    
 Pro Leu Gln Val Gly Ile Leu Pro
             260                



      <210> 1602
      <211> 371
      <212> PRT
      <213> Homo sapiens


      <400> 1602
 Met Ala Met Asn Leu Leu Val Leu Met Ser Thr Leu Val Ala Gly Ser
   1               5                  10                  15    
 Ser Ala Gly Glu Val Pro Asp Leu Gln His Pro Met Gln Arg Gly Ser
              20                  25                  30        
 Thr Ala Cys Ile Asn His Pro Arg Gly His Glu Glu Arg Pro Gln Gln
          35                  40                  45            
 Ser Gly Gly Ser Ser Phe Ser Ser Gly Phe Thr Ala Gly Asp Gly Val
      50                  55                  60                
 Ser Gly Ala Thr His Arg Arg Phe Thr Pro Thr Lys Cys His Pro Met
  65                  70                  75                  80
 Arg Lys Leu Arg Glu Lys Leu Ser Asn Leu Pro Lys Val Thr Tyr Leu
                  85                  90                  95    
 Ala Met His Lys Ser Cys Leu His Thr Arg Tyr Trp Asp Pro Gln Arg
             100                 105                 110        
 Leu Thr Lys Leu Gly Leu His Leu Arg Cys Leu Leu Ser Lys Thr Lys
         115                 120                 125            
 Leu Gly Lys Thr Ala Ser Asp Gly Phe Pro Ser Gly Glu Pro Glu Thr
     130                 135                 140                
 Val Gln Thr Gln Gly Pro Val Arg Arg Pro Thr Pro Arg Pro Ser Ala
 145                 150                 155                 160
 Pro Glu Arg Gly Arg His Ser Ala Leu Asn Ser Glu Gly Thr Arg Asp
                 165                 170                 175    
 Arg Ala Glu Leu Gly Cys Gly Gln Pro Thr Ala Ser Arg Arg Lys Val
             180                 185                 190        
 Gly Gly Pro Arg Leu Leu Arg Gly Pro Thr Asp Pro Cys Val Arg Arg
         195                 200                 205            
 Val Ala Pro Arg Ala Met Gly Ser Ala Ala Arg Arg Pro Arg Ala Thr
     210                 215                 220                
 Ser Leu Arg Pro Glu His Val Ala Pro Ala Glu Ala Thr Ser Gly Phe
 225                 230                 235                 240
 Tyr Thr Cys Trp Ala Ala Gly Glu Val Leu Pro His His Arg Arg Leu
                 245                 250                 255    
 Leu Ala Thr Gln Glu Thr Trp Ala Gly Ser Phe Pro Ala Val Arg Gly
             260                 265                 270        
 Pro Arg Ala Pro Arg Ser Gly Glu Cys Glu Lys Arg Asn Cys Asp Leu
         275                 280                 285            
 Ala Ala His Ser Ala Ser Ala Ile Gly Ser Gly Ser Leu Arg Gly Ala
     290                 295                 300                
 Arg Ala Pro Arg Cys Asp Cys Ser Arg Asp Gly Thr Ser Gln Gly Arg
 305                 310                 315                 320
 Ala Arg Glu Ile Trp Cys Val Pro Thr Pro Asn Pro Pro Leu Glu Ala
                 325                 330                 335    
 Ser Leu Thr Thr Arg Pro Gln Ala Ser Arg Leu Pro Val Ser Glu Val
             340                 345                 350        
 Val Pro Asn Arg Asn Ala Leu Lys Val Leu Ser Lys Ala Pro Phe Ile
         355                 360                 365            
 His Asp Leu
     370    



      <210> 1603
      <211> 158
      <212> PRT
      <213> Homo sapiens


      <400> 1603
 Met Leu Ala Trp Ile Ile Lys Leu Ile Gly Ser Phe Leu Gln Val Val
   1               5                  10                  15    
 Ser Ser Gln Thr Phe Leu Pro Val Thr Glu Val Leu Glu Lys Leu Thr
              20                  25                  30        
 Asn Val Ser Ser Lys Gln Ala Asn Cys Thr Lys Tyr Thr Lys His Thr
          35                  40                  45            
 Val Gln Tyr Asn Leu Ser His Ser Asp Ser Asp Ser Gln Lys Leu Thr
      50                  55                  60                
 Leu Glu Leu Arg Asp Gly Asn Asn Asn Val Lys Lys Glu Ala Ala Ala
  65                  70                  75                  80
 Gly Ser Ala Val Tyr Ser Lys Gly Lys Pro Pro Glu Leu Glu Thr Gly
                  85                  90                  95    
 Trp Lys Glu Gln Val Thr Ala His Lys Glu Arg Gly Pro Trp Leu Ser
             100                 105                 110        
 Asp Ser Thr Cys Arg Thr Ile Lys Cys Arg Lys Lys Glu Val Asn Ser
         115                 120                 125            
 Glu Glu Pro Gly Ile Gln Pro Thr Leu Asp Asn Thr Gln Ser His Gly
     130                 135                 140                
 Thr Tyr Leu Tyr Glu Lys Lys Leu Leu Ser Ser Cys His Ser
 145                 150                 155            



      <210> 1604
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 1604
 Met Asp Phe Arg Lys Trp Ala Tyr Thr Val Thr Lys Ser Met Ala Phe
   1               5                  10                  15    
 Ala Leu Pro Leu Phe Ile Ser Phe Leu Leu Ser Phe Leu Asn Asp Leu
              20                  25                  30        
 Glu Gly Lys Ser Lys Asp Ser Gln Gly Glu Leu Lys Ala Met Lys Arg
          35                  40                  45            
 Val Ala Glu Gly Ser Glu Glu Gln Glu Gly Gln Val Asp Ile Arg Ala
      50                  55                  60                
 Leu Val Asp Gln Gln Ala His Ser Ala Leu Glu Ala Glu Ala His Leu
  65                  70                  75                  80
 Cys Gln Ala Ala Thr Ser Gly Thr Ile Leu Arg Pro Arg Leu Gln Asp
                  85                  90                  95    
 Leu Gly Gly Leu Asp Leu Ala Gly Ile Gln Glu Met Phe Val Glu Ser
             100                 105                 110        
 Met Asn Glu Arg Met Asn Thr Met Arg Lys Phe Ser Asn Arg Tyr Leu
         115                 120                 125            
 Leu Asn Glu His Arg His Gln Ser Asp Tyr Gly Leu Pro Pro Thr Arg
     130                 135                 140                
 Pro Arg Ser Ser Thr Leu
 145                 150



      <210> 1605
      <211> 85
      <212> PRT
      <213> Homo sapiens


      <400> 1605
 Met Trp Asp Pro Arg Ala Lys Met Arg Ala Ser Leu Thr Phe Thr Pro
   1               5                  10                  15    
 Leu Val Ala Ser Ala Ser Pro Val Leu Gly Thr Arg Arg Ala Phe Val
              20                  25                  30        
 Gly Ala Val Leu Ser Leu Pro Gly Ser Gln Ala Leu Gln Cys Arg Gly
          35                  40                  45            
 Asn Arg Ile Ser Thr Gly Ser Trp Phe Ala Ser Tyr His Trp Asp Leu
      50                  55                  60                
 Leu Ile Gln Ser Val Leu Glu Tyr Glu Gln Arg Ile Tyr Lys Asn Ala
  65                  70                  75                  80
 Asp Arg Glu Pro Cys
                  85



      <210> 1606
      <211> 325
      <212> PRT
      <213> Homo sapiens


      <400> 1606
 Met His Ala Ala Ser Ala Leu His Leu Leu Pro Leu Ala Leu Arg Glu
   1               5                  10                  15    
 Pro Ala Ala Arg Arg Ser Ile Arg Arg Arg Asp Gly Thr Phe Asn Tyr
              20                  25                  30        
 Ser Pro Asp Val Tyr Cys Thr Lys Tyr Asp Glu Ala Thr Gly Pro Leu
          35                  40                  45            
 Pro Gly Gly Arg Arg Gly Ala Ser Gly His Gly Gly Leu Gln Asn Gly
      50                  55                  60                
 Gln Thr Thr Val Glu Gly Ser Ile Glu Gly Gln Ser Ala Gly Ala Ala
  65                  70                  75                  80
 Ser His Ala Met Ile Glu Lys Ile Leu Ser Glu Glu Pro Arg Trp Gln
                  85                  90                  95    
 Glu Thr Ala Tyr Val Leu Gly Asn Tyr Lys Thr Glu Pro Cys Lys Lys
             100                 105                 110        
 Pro Pro Arg Leu Cys Arg Gln Gly Tyr Ala Cys Pro Tyr Tyr His Asn
         115                 120                 125            
 Ser Lys Asp Arg Gly Arg Ser Pro Arg Lys His Lys Tyr Arg Ser Ser
     130                 135                 140                
 Pro Cys Pro Asn Val Lys His Gly Asp Glu Trp Gly Asp Pro Gly Lys
 145                 150                 155                 160
 Cys Glu Asn Gly Asp Ala Cys Gln Tyr Cys His Thr Arg Thr Glu Gln
                 165                 170                 175    
 Gln Phe His Pro Glu Ile Tyr Lys Ser Thr Lys Cys Asn Asp Met Gln
             180                 185                 190        
 Gln Ser Gly Ser Cys Pro Arg Gly Pro Phe Cys Ala Phe Ala His Val
         195                 200                 205            
 Glu Gln Pro Pro Leu Ser Asp Asp Leu Gln Pro Ser Ser Ala Val Ser
     210                 215                 220                
 Ser Pro Thr Gln Pro Gly Pro Val Leu Tyr Met Pro Ser Ala Ala Gly
 225                 230                 235                 240
 Asp Ser Val Pro Val Ser Pro Ser Ser Pro His Ala Pro Asp Leu Ser
                 245                 250                 255    
 Ala Leu Leu Cys Arg Asn Ser Ser Leu Gly Ser Pro Ser Asn Leu Cys
             260                 265                 270        
 Gly Ser Pro Pro Gly Ser Ile Arg Lys Pro Pro Asn Leu Glu Gly Ile
         275                 280                 285            
 Val Phe Pro Gly Glu Ser Gly Leu Ala Pro Gly Ser Tyr Lys Lys Ala
     290                 295                 300                
 Pro Gly Phe Glu Arg Glu Asp Gln Val Gly Ala Glu Tyr Leu Lys Asn
 305                 310                 315                 320
 Phe Lys Cys Gln Asp
                 325



      <210> 1607
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 1607
 Met Pro Thr Trp Gly Ala Leu Arg Leu Gly Gly Val Pro Ser Leu Val
   1               5                  10                  15    
 Thr Pro Leu Ser Leu Pro Leu Ile Gly Leu Leu Pro Ser Thr Tyr Val
              20                  25                  30        
 Lys Met Leu Leu Ser Ala Arg Asp Met Leu Thr Leu Gln Thr Ser Gly
          35                  40                  45            
 Glu Leu Glu Phe Glu Pro Arg Ala Phe Phe Thr Thr Ile Ser Val Val
      50                  55                  60                
 Ser Gly Ser Thr Leu Gln Ala Gly Gln Pro Ala Ser Arg Gly Leu Pro
  65                  70                  75                  80
 Trp Gly Trp Asn Val Cys Arg Met Pro Leu
                  85                  90



      <210> 1608
      <211> 51
      <212> PRT
      <213> Homo sapiens


      <400> 1608
 Met Glu Gln Leu Cys Ile Leu Thr Val Val Val Ala Asn Ala Thr Phe
   1               5                  10                  15    
 Thr Cys Ile Phe Ser Ser Lys Pro Thr Met Asp Thr Gln Leu Ala Ser
              20                  25                  30        
 Phe Leu Leu Ala Ser Asp Leu Pro Met Met Ile Pro Asp Ser Lys Arg
          35                  40                  45            
 Phe Pro Phe
      50    



      <210> 1609
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 1609
 Met Val Leu Ile Ser Cys Tyr Ser Leu Ala Phe Glu Ser Leu Ile Val
   1               5                  10                  15    
 Leu Lys Lys Ala Ile Ile Glu Ala Ala Val Arg Ile Ala Val Gln Pro
              20                  25                  30        
 Arg Gln Phe Asn Leu Ser Asp Thr Asp Lys Ile Glu Tyr Ser Glu Met
          35                  40                  45            
 Arg Lys Lys Leu Glu Val Thr Gly Cys Gln Ser Ser Ser Leu Pro Leu
      50                  55                  60                
 Thr Gly Cys Val Thr Leu Ser Lys Pro Ser Thr Ser Val Trp Asp His
  65                  70                  75                  80
 Thr Arg Ser Ala Gly Leu Asn Leu Leu Glu Met Met Gly Leu Phe Glu
                  85                  90                  95    
 Asn Glu Asn Glu Glu Pro Asn Ser Pro Gln Lys Asp Met Leu Asn Asp
             100                 105                 110        
 Thr His Asn Val Lys Pro Pro Thr Phe Leu Ile Gln Thr Tyr Ser Gln
         115                 120                 125            
 Gln Leu Thr Tyr Phe Ala Asp Lys Thr Ala Thr Ile Gln Arg
     130                 135                 140        



      <210> 1610
      <211> 414
      <212> PRT
      <213> Homo sapiens


      <400> 1610
 Met Arg Gly Ser Lys Arg Gln Ala Ser Gly Leu Tyr Tyr Ile Ile Ala
   1               5                  10                  15    
 Cys Leu Cys Trp His Val Ala Ile Arg Pro Gly Gly Thr Ala Ile Asn
              20                  25                  30        
 Lys Pro Gly Val Ile Arg Val Arg Asn Arg Glu Glu Gly Asn Val Gly
          35                  40                  45            
 Lys Trp Gly Glu Arg Gln Val Asp Gln Arg Asp Ala Val Met Arg Val
      50                  55                  60                
 Lys Cys Gly Ile Arg Asn Asn Val Arg Gly His Ile Glu Val Arg Ala
  65                  70                  75                  80
 Arg Asn Asn Gly Asn Cys Gly Arg Leu Asn Lys Glu Ala Ser Glu Ala
                  85                  90                  95    
 Ile Gly Gln Cys Gln Ser Ser Ala Ala Lys Pro Arg Arg Ser Gly Lys
             100                 105                 110        
 Glu Ser Ala Glu Ser Leu Gly Pro Glu Phe Gln Gly Leu Trp Glu Trp
         115                 120                 125            
 Leu Pro Gly Thr Arg Ala Asn Gln Arg Met Gly Pro Glu Val Asn Pro
     130                 135                 140                
 Gln Lys Thr Val Ala Ala Leu Gln Lys Arg Asn Leu Ile Ile Glu Arg
 145                 150                 155                 160
 Lys Thr Asn Lys Gln Lys Val Thr Thr Ala Ser Ser Thr Thr Thr Thr
                 165                 170                 175    
 Thr Thr Thr Ile Lys Ala Pro Thr Lys Ala Pro Ser Lys Gly Gln Gln
             180                 185                 190        
 Pro Gln Arg Pro Lys Leu Asp Lys Leu Thr Lys Met Arg Lys Asn Gln
         195                 200                 205            
 Gln Lys Met Leu Lys Thr Gln Lys Ala Arg Val Pro Leu Leu Leu Gln
     210                 215                 220                
 Met Ile Thr Gly Leu Gln Cys Leu Ser Ile Lys Asp Ala Glu Leu Asp
 225                 230                 235                 240
 Arg Gly Ser Asp Gly Arg Leu Asp Arg Asn Arg Ser Ala Arg Gln Lys
                 245                 250                 255    
 Ile Asn Lys Val Ile Gln Asp Leu Tyr Ser Thr Leu Asp Gln Val Asp
             260                 265                 270        
 Leu Val Asp Phe Tyr Arg Thr Leu Tyr Ala Lys Ser Thr Glu Tyr Thr
         275                 280                 285            
 Phe Phe Ser Gly Pro His Gly Thr Tyr Ser Lys Ile Asp His Ile Ile
     290                 295                 300                
 Gly Ser Lys Thr Leu Leu Ser Lys Cys Lys Gly Thr Glu Ile Ile Thr
 305                 310                 315                 320
 Asn Ser Pro Ser Glu Tyr Ser Ala Ile Lys Leu Glu Leu Arg Val Thr
                 325                 330                 335    
 Lys Leu Thr Gln Asn His Thr Ile Ser Trp Lys Leu Asn Asn Leu Ile
             340                 345                 350        
 Leu Asn Asp Ser Trp Val Asn Asn Glu Thr Lys Ala Glu Ile Lys Lys
         355                 360                 365            
 Val Phe Glu Thr Asn Gly Asn Lys Glu Thr Thr Tyr Gln Asn Leu Trp
     370                 375                 380                
 Asp Thr Asp Lys Ala Val Leu Arg Gly Lys Phe Ile Ala Leu Asn Thr
 385                 390                 395                 400
 His Ile Arg Lys Leu Lys Lys Ser Gln Ile Asp Thr Leu Pro
                 405                 410                



      <210> 1611
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1611
 Met Ile Leu Met Thr Ala Pro Val Thr Ser Ser Ile Ser Cys Thr Thr
   1               5                  10                  15    
 Glu Ile Leu Met Leu Ile Ser Ile Leu Leu Leu Ser Leu Met Gln Glu
              20                  25                  30        
 Asp Gln Asp Asn Thr Val Ala Leu Gly Ala Glu His Gly Gln Ala Leu
          35                  40                  45            
 Asn Ala Glu Ser Ser Lys Leu Ala Phe Val Phe Ser Cys Trp Phe Gln
      50                  55                  60                
 Ala Glu Glu Ser Leu Trp Asn Arg Thr Ala Gln Ala Leu Leu Gly Lys
  65                  70                  75                  80
 Ala Gly Tyr Gly His Leu Leu Arg Trp Gly Ala Tyr Gly Asp Ser Ser
                  85                  90                  95    
 Asn Arg Arg Thr Ala Asn Asp Ser Val Lys Tyr Phe Val Leu Phe Leu
             100                 105                 110        
 Ser Leu Lys His Met Gln Leu Pro Cys Cys Asp Asn Gly Phe Lys Gln
         115                 120                 125            
 Glu Ser Phe
     130    



      <210> 1612
      <211> 241
      <212> PRT
      <213> Homo sapiens


      <400> 1612
 Met Gly Gln Val Trp Cys Leu Val Cys Ile Thr Leu Glu Leu Phe His
   1               5                  10                  15    
 Thr Asp Asn Glu Glu Glu Gln Glu Tyr Ser Glu Val Thr Lys Glu Val
              20                  25                  30        
 Thr Glu His Val Tyr Leu Pro Ala Lys Ala Lys Ala Ala Lys Glu Gly
          35                  40                  45            
 Glu Val His Pro Tyr Pro Ser Ala Pro Pro Pro Tyr Tyr Phe Glu Asp
      50                  55                  60                
 Lys Asp Pro Pro Asp Leu Ser Phe Leu Glu Asp Thr Gly Gln Lys Val
  65                  70                  75                  80
 Val Ala Pro Ala Gly Ile Gln Gln Ala Arg Arg Glu Gly Asp Leu Glu
                  85                  90                  95    
 Ala Trp Gln Phe Pro Val Arg Ile His Pro Pro Asp Gln Gln Gly Asn
             100                 105                 110        
 Ile Ile Ala Thr Phe Glu Pro Phe Pro Phe Lys Phe Gly Lys Ala His
         115                 120                 125            
 Ser Val Asp Tyr Ile Lys Ala Cys Asp Gly Ile Gly Gly Asn Leu His
     130                 135                 140                
 Lys Ala Thr Leu Leu Ala Gln Ala Leu Ala Gly Leu Arg Val Asp Lys
 145                 150                 155                 160
 Gly Asn Thr Pro Phe Pro Gly Ala Cys Phe Asn Cys Gly Lys His Gly
                 165                 170                 175    
 His Thr Lys Lys Glu Cys Arg Lys Asn Gln Arg Val Arg Leu Pro Asp
             180                 185                 190        
 Arg Gly Lys Lys Lys Thr Val Glu Pro Glu Ile Cys Pro Lys Cys Lys
         195                 200                 205            
 Lys Gly Lys His Trp Ala Ser Gln Cys His Ser Lys Phe Asp Lys Glu
     210                 215                 220                
 Arg Asn Pro Ile Ser Gly Asn Ala Met Arg Gly Pro Ser Arg Ala Leu
 225                 230                 235                 240
 Phe
    



      <210> 1613
      <211> 221
      <212> PRT
      <213> Homo sapiens


      <400> 1613
 Met Ile Thr Leu Ala Ala Arg His Arg Ala Thr Leu Leu Leu Leu Leu
   1               5                  10                  15    
 Val Thr His Thr His Met His Met His Ala Cys Cys Met His Thr His
              20                  25                  30        
 Thr Pro Gly Lys Ser Pro Glu Val Ala Ile Pro Val Tyr Ile Pro Ala
          35                  40                  45            
 Asn Ser Ala Gln Gly Phe His Phe Leu His Arg Gly Gln Ala Leu Leu
      50                  55                  60                
 Asp Gln Ala Ala Ser Trp Asp Asp Gln Ile Arg Ala Leu Gly Cys Asp
  65                  70                  75                  80
 Glu Gly Asn Pro Phe Val Lys Leu Lys Gly Glu Leu Ser Ala Ala Ala
                  85                  90                  95    
 Phe Leu Ser Thr Leu Arg Ile Pro Glu Ile Gly Gln Ala Leu Leu Leu
             100                 105                 110        
 Gly Ser Ser Val Pro Arg Asp Leu Thr Phe Ser Gly Gly Asp His Asp
         115                 120                 125            
 Tyr Leu Leu Glu Gly Ser Arg Gly Ser Ala Arg Arg Thr Gly Gly Leu
     130                 135                 140                
 Lys Met Ser Arg Lys Pro Glu Asn Ser Leu Arg His Cys His Arg Gly
 145                 150                 155                 160
 Ala Leu Gln His Leu Lys Arg Asp Ser Gly Gln Ala Ser Ala Gly Arg
                 165                 170                 175    
 His Leu Ser Phe Gly Phe Ala Gln Ser Ser Val Arg Ser Glu Leu Ser
             180                 185                 190        
 Leu Trp His Ser Leu His Phe Pro Leu Asn Gly Gln Asn Asn Pro Val
         195                 200                 205            
 Asn Ala Pro Pro Glu Arg Ala Asp Trp Ile Leu Ala Met
     210                 215                 220    



      <210> 1614
      <211> 305
      <212> PRT
      <213> Homo sapiens


      <400> 1614
 Met Ser Thr Ala Val Val Val Lys Val Val Leu Cys Thr Val Ala Pro
   1               5                  10                  15    
 Gly Arg Gly Ser Ala Pro Ser Leu Ser Ser Cys Leu Asp Trp Lys Val
              20                  25                  30        
 Asn Gly Ala Glu Gly Ser His Asn Lys Asp Leu Phe Val Leu Thr Tyr
          35                  40                  45            
 Gly Ala Leu Val Ala Gln Leu Cys Lys Asp Tyr Glu Lys Asp Glu Asp
      50                  55                  60                
 Val Asn Gln Tyr Leu Asp Lys Met Gly Tyr Gly Ile Gly Thr Arg Leu
  65                  70                  75                  80
 Val Glu Asp Phe Leu Ala Arg Ser Cys Val Gly Arg Cys His Ser Tyr
                  85                  90                  95    
 Ser Glu Ile Ile Asp Ile Ile Ala Gln Asp Met Glu Arg Gly Phe Cys
             100                 105                 110        
 Ala Leu His Ile Asp Thr Glu Gly Arg Tyr Glu Trp Trp Thr Thr Ser
         115                 120                 125            
 Thr Gln Leu Gln Ser Thr Leu Pro Arg Ala Ala Gln Cys Ser Val Tyr
     130                 135                 140                
 Gln Lys Gln Pro Asp Arg Lys Ser Leu Thr Val Gly Gln Lys Ile Glu
 145                 150                 155                 160
 Val Gly Asn Pro Gly Ile Gly Thr Glu Gln Ser Pro Gln Gly Leu Val
                 165                 170                 175    
 Arg Phe Ala Thr Gln Ala Phe Leu Thr Thr His Arg Ala Glu Gly Leu
             180                 185                 190        
 Gln Gln Ser Gln Val Lys Gly Ser Val Ile His Leu Lys Ser Gln Asp
         195                 200                 205            
 Lys Cys Gly Glu His Arg Phe Thr Thr Asn Gln Val Glu Thr Gly Asp
     210                 215                 220                
 Pro Val Arg Glu Ser Ser Ser Gln His Ser Val Gly Arg Gly Gly Pro
 225                 230                 235                 240
 Lys Asp Ile Gln Ile Gln Gly Ala Asn Val Pro Val Arg Gln Cys Asn
                 245                 250                 255    
 Leu Leu Trp Arg Ile Thr Leu Gly Pro Leu Glu Thr Pro His Leu Glu
             260                 265                 270        
 Phe Ser Gly Glu Cys Ser Leu Leu Ala Ala Met Glu Ala Pro Glu His
         275                 280                 285            
 Thr Trp Asp Gln Glu Lys Ser Asp Ile Pro Glu Pro Pro His Arg Ser
     290                 295                 300                
 Ser
 305



      <210> 1615
      <211> 230
      <212> PRT
      <213> Homo sapiens


      <400> 1615
 Met Glu Ala Val Leu Phe Pro Ala Cys Leu Cys His Arg Val Leu Leu
   1               5                  10                  15    
 Cys Ser Leu Ser Leu Lys Ala Ser Ser Val Ser Gly Pro Leu Arg Arg
              20                  25                  30        
 Pro Val Cys Met Asn Gln Arg Leu Asp Ser Ala Ser Val Thr Ile Thr
          35                  40                  45            
 Val Trp Tyr His Glu Glu Gly Cys Phe Leu Tyr Gly Ser Arg Gln Asn
      50                  55                  60                
 Glu Tyr Leu Lys Ser Arg Ala Pro Gly Glu Met Lys Asn Gln Gly Ser
  65                  70                  75                  80
 Ser Glu Gln Arg Leu Lys Asp His Leu Asn Lys Asp Ile His Ile Tyr
                  85                  90                  95    
 Thr Thr Asp Asp Leu Ala Ser Met Glu Glu Trp Arg Asn Gln Ile Pro
             100                 105                 110        
 Lys Glu Glu His Tyr Gly Leu Gln Leu His Pro Ala Ile His Gln Leu
         115                 120                 125            
 Lys Thr Glu Glu Cys Asn His Thr Gln Thr Asp Phe Phe Thr Arg Gln
     130                 135                 140                
 Phe Leu Pro Leu Glu Arg Val Gln Ile Leu Lys Ser Ile Ile Tyr Lys
 145                 150                 155                 160
 Pro Leu Leu Tyr Leu Pro Leu Phe Glu Ser Lys Gln Lys Tyr Lys Glu
                 165                 170                 175    
 Ser Asp Pro Gln Met Ser Arg Phe Ile Leu Pro Tyr Leu Ser Val Gln
             180                 185                 190        
 Ser Met Ala Asn His Pro Met Asp Gly Gln Ser Gln Gly Pro Asn Gln
         195                 200                 205            
 Gly Val Leu Tyr Glu Gln Ala Glu Gly Leu Gln Trp Leu Phe Val Gly
     210                 215                 220                
 Phe Trp Leu Glu Leu Asn
 225                 230



      <210> 1616
      <211> 187
      <212> PRT
      <213> Homo sapiens


      <400> 1616
 Met Lys Asp Trp Ser Tyr Gly Asp Ser Gly Pro Leu Ala Leu Leu Ile
   1               5                  10                  15    
 Arg Met Lys Thr Leu Leu Phe Gly Val Trp Thr Leu Leu Ala Leu Ile
              20                  25                  30        
 Leu Cys Pro Glu Pro Pro Glu Gln Val Ile Leu Glu Leu Gln Pro Ala
          35                  40                  45            
 Trp Val Ala Val Asp Glu Ala Phe Thr Val Lys Cys His Val Pro Ser
      50                  55                  60                
 Val Ala Pro Leu Glu Ser Leu Thr Leu Ala Leu Leu Gln Gly Asn Gln
  65                  70                  75                  80
 Glu Leu His Arg Lys Asn Phe Thr Ser Leu Ala Val Ala Ser Gln Arg
                  85                  90                  95    
 Ala Glu Val Ile Ile Ser Val Arg Ala Gln Lys Glu Asn Asp Arg Cys
             100                 105                 110        
 Asn Ser Ser Cys His Ala Glu Leu Asp Leu Ser Leu Gln Gly Phe Pro
         115                 120                 125            
 Pro Pro Ile Leu Glu Leu Lys Glu Ser Tyr Pro Leu Ala Gly Thr Asp
     130                 135                 140                
 Ile Asn Val Thr Cys Ser Gly His Val Leu Thr Ser Pro Ser Pro Thr
 145                 150                 155                 160
 Leu Arg Leu Gln Gly Ala Pro Asp Leu Pro Ala Gly Glu Pro Ala Trp
                 165                 170                 175    
 Leu Leu Leu Thr Ala Arg Glu Glu Asp Asp Gly
             180                 185        



      <210> 1617
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1617
 Met Met Gly Asn Ile Val Arg Pro Val Asn Ser Met Ser Leu Ser Pro
   1               5                  10                  15    
 Leu Leu Pro Leu Phe Ser Cys Lys Val Ser Val Leu Val Arg Gly Asn
              20                  25                  30        
 Ala Val Trp Asn Thr Met Met Val Asp Lys Ala Phe His Asp Ser Thr
          35                  40                  45            
 Asp Gly Ser Leu Gly Arg Ser Ile Val Cys Arg Ile Gly Lys Pro Leu
      50                  55                  60                
 Ser Arg Gly Ser Val Tyr Ser Thr Glu Gly Lys Leu Leu Leu Val Gly
  65                  70                  75                  80
 Leu Met Asp Arg Asn Glu Glu Lys Ala Phe Val Lys Ser Met Ala Ala
                  85                  90                  95    
 Tyr Arg Val Pro Gly Asp Val Leu Ile Cys Pro Ser Asn Glu Thr Thr
             100                 105                 110        
 Ser Gly Ile Ala Ala Ala Ile Gly Ile Thr Thr Trp Leu Thr Leu
         115                 120                 125        



      <210> 1618
      <211> 195
      <212> PRT
      <213> Homo sapiens


      <400> 1618
 Met Lys Leu Phe Gln Phe Leu Lys Leu Thr Asn Trp Val Leu Pro Lys
   1               5                  10                  15    
 Ile Thr Lys Phe Ile Pro Ile Glu Gly Ala Glu Asn Val Phe Thr Asp
              20                  25                  30        
 Gly Ser Ser Asn Gly Lys Ala Ser Tyr Ser Gly Ser Lys Cys Lys Val
          35                  40                  45            
 Phe Gln Thr Pro Tyr Thr Leu Ala Pro Lys Val Glu Leu Val Ala Val
      50                  55                  60                
 Ile Glu Val Leu Thr Ala Phe Asp Met His Ile Asn Val Ile Ser Asp
  65                  70                  75                  80
 Ser Ser Tyr Val Val His Ser Thr Gln Leu Thr Glu Asn Ala Gln Leu
                  85                  90                  95    
 Arg Phe His Thr Asp Glu Gln Leu Ile Thr Leu Phe Thr Gln Leu Gln
             100                 105                 110        
 Thr Ala Val Arg Ser Arg Met Ala His Thr Pro Leu Pro Gly Leu Leu
         115                 120                 125            
 Thr Ala Gly Asn Gln Met Ala Asp Arg Leu Val Ala Thr Ala Ile Ser
     130                 135                 140                
 Asn Ala Arg His Phe Arg Asn Leu Thr His Val Asn Ala Ser Gly Leu
 145                 150                 155                 160
 Lys Arg Arg Tyr Ser Ile Thr Trp Lys Lys Ala Lys Ala Ile Ile Gln
                 165                 170                 175    
 His Cys Pro Thr Cys His Met Val His Ser Ser Ser Phe Thr Gly Gly
             180                 185                 190        
 Val Asn Pro
         195



      <210> 1619
      <211> 161
      <212> PRT
      <213> Homo sapiens


      <400> 1619
 Met Ala Thr Arg Val Gln Ala Arg Ala Cys Leu Leu Pro Ala Leu Ala
   1               5                  10                  15    
 Pro Arg Ile Pro Thr Leu Glu Arg Asn Glu Phe Arg Ala Trp Thr Asp
              20                  25                  30        
 Ile Lys Pro Val Lys Pro Ile Lys Ala Lys Pro Gln Tyr Lys Pro Pro
          35                  40                  45            
 Asp Asp Lys Met Val His Glu Thr Ser Tyr Ser Ala Gln Phe Lys Gly
      50                  55                  60                
 Glu Ala Ser Lys Pro Thr Thr Ala Asp Asn Lys Val Ile Asp Arg Arg
  65                  70                  75                  80
 Arg Ile Arg Ser Leu Tyr Ser Glu Pro Phe Lys Glu Pro Pro Lys Val
                  85                  90                  95    
 Glu Lys Pro Ser Val Gln Ser Ser Lys Pro Lys Lys Thr Ser Ala Ser
             100                 105                 110        
 His Lys Pro Thr Arg Lys Ala Lys Asp Lys Gln Ala Val Ser Gly Gln
         115                 120                 125            
 Ala Ala Lys Lys Lys Ser Ala Glu Gly Pro Ser Thr Thr Lys Pro Asp
     130                 135                 140                
 Asp Lys Glu Gln Ser Lys Glu Met Asn Asn Lys Leu Ala Glu Ala Lys
 145                 150                 155                 160
 Glu
    



      <210> 1620
      <211> 181
      <212> PRT
      <213> Homo sapiens


      <400> 1620
 Met Ala Leu Ala Leu Ser Gly Leu Lys Leu Cys Thr Arg Leu Leu Ser
   1               5                  10                  15    
 Ile Leu Thr Glu Glu Ile Trp Lys Pro Ser Thr Ala Ala Pro Tyr Arg
              20                  25                  30        
 Tyr Pro Lys Gly Lys Cys Met His Ala Val Arg Asp Asp Glu His Cys
          35                  40                  45            
 Val Trp Lys Leu Leu Lys Gly Thr His Val Ser Ser Ala Ala Asp Ser
      50                  55                  60                
 Ser Glu Glu Thr Pro Arg Glu Phe Glu Thr Ala Glu Gly Gly Arg Val
  65                  70                  75                  80
 Pro Gln Gln Pro Thr Leu Gln Leu Arg Pro Leu Lys Phe Ser Ala Thr
                  85                  90                  95    
 Phe Leu Asn Tyr Asp Asp Gly Thr Glu Ala Leu Glu Gly Ser His Leu
             100                 105                 110        
 Pro Glu Gly Val Gly Ser Ser Ser Arg Ala Glu Val Phe Leu Gly Val
         115                 120                 125            
 Leu Glu His Val Pro Leu Leu Leu Tyr Ile Leu Ala Ala Lys Thr Leu
     130                 135                 140                
 Ile Leu Cys Leu Thr Phe Ala Gly Val Lys Met Tyr Gln Arg Lys Arg
 145                 150                 155                 160
 Leu Glu Ala Lys Gln Gln Lys Leu Glu Ala Glu Arg Lys Lys Gln Ser
                 165                 170                 175    
 Glu Lys Lys Asp Asn
             180    



      <210> 1621
      <211> 164
      <212> PRT
      <213> Homo sapiens


      <400> 1621
 Met Leu Ser Lys Ser Gln Cys Leu Lys Leu Val Thr Leu Lys Ala His
   1               5                  10                  15    
 Leu Val Leu Tyr Ser Thr Val Thr Lys Val Val Leu Lys Gly Asn Tyr
              20                  25                  30        
 Pro Val Asp Ile Tyr Leu Val Pro Val Thr Phe Arg Lys Leu Phe Gly
          35                  40                  45            
 Ser Trp Arg Glu Asn Ala Arg Asp Lys Met Ile Ser Val Tyr Glu Asn
      50                  55                  60                
 Trp Lys Leu Val Gln Leu Arg Thr Ser Lys Leu Lys Tyr Glu Arg Gln
  65                  70                  75                  80
 Arg Thr His Val Val Lys Asp Val Pro Val Ala Leu Phe Leu Ser Leu
                  85                  90                  95    
 Arg Asn Phe Glu Ala Gly Ser Tyr Gln Met Leu Phe Thr Val Ser Gly
             100                 105                 110        
 Glu Gln Arg Leu Lys Lys Glu Leu Thr Leu Ala Val Val Leu Ile Gly
         115                 120                 125            
 Val His Pro Gly Tyr Glu Gly Leu Leu Ala Ser Pro Ser Asn Gln Thr
     130                 135                 140                
 Leu Thr Tyr Ser Phe Thr Asp Asn Glu Arg Gly Ser Gln Gly Val Gln
 145                 150                 155                 160
 Ile Phe Met Val
                



      <210> 1622
      <211> 158
      <212> PRT
      <213> Homo sapiens


      <400> 1622
 Met Ala Arg Leu Glu Ala Leu Gly Pro Leu Gly Leu Cys Thr Pro Thr
   1               5                  10                  15    
 Pro Ser His Leu Ala Cys Leu Leu Ile Phe Met Gly Ala Trp Gly Asp
              20                  25                  30        
 Gln Leu Trp Leu Leu Val Ile Val Ala Gln Val Thr Val His Thr Ser
          35                  40                  45            
 Trp Asp Gln Asp Ile Arg Ala Leu Arg Arg Val Lys Gly Pro Ser Gly
      50                  55                  60                
 Pro Ser Leu Leu Leu Thr Ala Gly Lys Cys Lys Arg Val Asp Gln Ser
  65                  70                  75                  80
 Thr Lys Gly Ser Leu Gly Arg His Arg Lys Ser Val Ile Val Met Pro
                  85                  90                  95    
 Leu Glu Gly Val Leu Val Met Gly Asp Cys Leu Phe Ala Gly Asp Pro
             100                 105                 110        
 Met Tyr Leu Leu Ile Ala Glu Ala Gly Glu Cys Thr Pro Phe Gln Glu
         115                 120                 125            
 Ile Lys Met Gly Gln Asn Ser Glu Arg Ser Glu Ile Pro Lys Val Leu
     130                 135                 140                
 Leu Ser Leu Gln Gln Thr Asn Phe Cys Cys Lys Asn Leu Thr
 145                 150                 155            



      <210> 1623
      <211> 251
      <212> PRT
      <213> Homo sapiens


      <400> 1623
 Met Gly Ser Trp Leu Gln Gly Leu Arg Ala Met Val Phe Ala Leu Asn
   1               5                  10                  15    
 Tyr Met Val Thr Arg Val Arg Asn Lys Lys Asp Pro Pro Thr Thr Ser
              20                  25                  30        
 Gly Pro Gln Thr His Gln Pro Lys Lys His Leu Thr Asn Phe Lys Ser
          35                  40                  45            
 Glu Thr Lys Glu Thr Arg Phe Ile Cys Gly Pro Lys Thr Pro Ala Pro
      50                  55                  60                
 Leu Met Asp Trp Glu Gly Ser Leu Pro Leu Met Phe Asn His Cys Arg
  65                  70                  75                  80
 Asp Thr Ser Leu Ile Ile His Pro Cys Phe Gln Gly Val Arg Pro Cys
                  85                  90                  95    
 Arg Asp Ala Cys Leu Ser Pro Ser Pro Leu Ala Ala Ser Pro Ala Phe
             100                 105                 110        
 Leu Gly Lys Gly Gln Val Pro Leu Asn Pro Phe Phe Thr Leu Ser Gly
         115                 120                 125            
 Lys Ser Arg Phe Ser Gly Gly Gly Ala Ser Thr Pro Thr Pro Ser Phe
     130                 135                 140                
 His Val Ser Thr Pro Ser Leu Leu Phe Trp Gly Arg Gly Lys Tyr Pro
 145                 150                 155                 160
 Ser Thr Pro Ser Ser Pro Leu Val Ala Ser Pro Ala Phe Leu Gly Lys
                 165                 170                 175    
 Gly Gln Val Pro Leu Asn Pro Phe Phe Thr Leu Ser Gly Lys Ser Arg
             180                 185                 190        
 Phe Ser Gly Glu Gly Ala Lys Ala Pro Glu Thr Ile Thr Asp Ala Glu
         195                 200                 205            
 Leu Arg Val Thr Leu Thr Val Glu Ala Ala Val Cys Ser Thr Ile Ala
     210                 215                 220                
 Leu Ser Leu Gly Trp Glu Ile Leu Pro Arg His Trp Gly Lys Glu Glu
 225                 230                 235                 240
 Val Thr Lys Thr Ile Tyr Tyr Pro Val Ile Pro
                 245                 250    



      <210> 1624
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 1624
 Met Gly Leu Ile Val Val Thr Leu Phe Val Ser Ser Ile Thr Pro Gly
   1               5                  10                  15    
 Thr Glu Arg Val Gln Ala Gly Thr Asp Pro Ser Leu Ser Phe Glu Ile
              20                  25                  30        
 Gln Gln Lys Ile Leu Met Glu Glu Glu Asp Thr Lys Arg Glu Val Pro
          35                  40                  45            
 Lys Glu Asp Gly Val Gly Asp Val Gln His Phe Gly Arg Gly Gly Arg
      50                  55                  60                
 Lys
  65



      <210> 1625
      <211> 100
      <212> PRT
      <213> Homo sapiens


      <400> 1625
 Met Asp Arg Cys Pro Ser Ile Leu Pro Leu Pro Val Arg Leu Val Phe
   1               5                  10                  15    
 Gln Ile Leu Leu Thr Gly Gly Ser Cys Ala Glu Gly Met Lys His Arg
              20                  25                  30        
 Val Gln Arg Ser Val Gly Lys Ser Pro Gly Arg Asp Leu Arg Gln Glu
          35                  40                  45            
 Gly Ser Leu Glu Lys Trp Arg Cys Ala Trp Cys Val Ala Leu Arg Val
      50                  55                  60                
 Cys Glu His Ala Leu Val Asp Leu Arg Leu Asp Tyr Arg Ala Ser Leu
  65                  70                  75                  80
 Ser Glu Gly Ser Val Met Leu Ser Tyr Ala Ile His Leu Asn Ser Ala
                  85                  90                  95    
 Ala His Arg Leu
             100



      <210> 1626
      <211> 210
      <212> PRT
      <213> Homo sapiens


      <400> 1626
 Met Trp Leu Pro Ala Val Ala Leu Leu Ala Gly Ser Gly Trp Cys Pro
   1               5                  10                  15    
 Gly Pro Arg Pro Pro Val Pro Ser Ser Gln Arg Ser Leu Val Gln Arg
              20                  25                  30        
 Lys Leu Lys Gln Ala Pro Pro Ala Gly Leu Leu Gln Gln Ile Pro Tyr
          35                  40                  45            
 Pro Leu Glu Gln Asn Ser Lys Pro Val Leu Trp Lys Trp Thr Trp Thr
      50                  55                  60                
 Ala Gln Thr Glu Leu Gly Gln Ser Gln Glu Ala Gly His Arg Leu Leu
  65                  70                  75                  80
 Gly Pro Asp Pro Glu Leu Asp Ala Glu Ser Leu Gly Arg Lys Ser Gly
                  85                  90                  95    
 Leu Gln Gly Pro Trp Ala Ala Gly Met Glu Ala Gly Ser Ser Leu Asp
             100                 105                 110        
 Thr Gly Ser Ser Leu Ser Thr Asp Arg Tyr Arg Thr Lys Lys Asn Ile
         115                 120                 125            
 Ser Val Glu Ile Asn Glu Met Lys Asn Arg Lys Thr Ile Pro Thr Ile
     130                 135                 140                
 Asn Glu Thr Lys Pro Asp Ser Leu Arg Arg Pro Val Lys Val Ile Thr
 145                 150                 155                 160
 Leu Trp Ser Asp Arg Ser Arg Arg Lys Arg Glu Lys Thr Gln Ile Thr
                 165                 170                 175    
 Asn Thr Arg Asn Glu Asn Ser Asp Thr Ala Thr Asp Ser Ala Ala Leu
             180                 185                 190        
 Leu Leu Gly Leu Pro Phe Thr His Met Gln Ala Tyr Leu Pro Ala Pro
         195                 200                 205            
 Pro Ala
     210



      <210> 1627
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1627
 Met Ala Ala Ser Trp Asn Cys Leu Arg Trp Arg Ser Arg Ala Leu Leu
   1               5                  10                  15    
 Trp Thr Ala Ala Leu Leu Cys Ser Pro Ala Ala Ala Lys Ser Val Leu
              20                  25                  30        
 Ser Ile Ala Asp Gly Asp Glu Ile Glu Arg Trp Glu Trp Lys Gly Asn
          35                  40                  45            
 Phe Thr Leu Lys Gly Val Gln Ile Leu Cys Pro Arg Glu Ile Arg Gly
      50                  55                  60                
 Asn Thr Phe Glu Glu Val Gly Leu Arg Thr Phe Phe Leu Lys Thr Lys
  65                  70                  75                  80
 Ala Ser Tyr Ser Ser Val Ser Ser Gly Asn Glu Arg Asp Pro Asp Leu
                  85                  90                  95    
 Leu Arg Glu Pro Ala Ala Pro Gln Ser Ser Pro Leu Gln Asn Pro Lys
             100                 105                 110        
 Gly Asp Cys Gly Arg Arg Ile Cys Phe Phe Ala Pro Asn Lys Lys Gln
         115                 120                 125            
 Gly Phe Met Leu Leu Leu Val
     130                 135



      <210> 1628
      <211> 342
      <212> PRT
      <213> Homo sapiens


      <400> 1628
 Met Ala Arg Ser Glu Gly Ala Trp Val Gly Cys Lys Leu Ala Val Gln
   1               5                  10                  15    
 Leu Ser His His Met Ser Leu Ala Trp Leu Lys Val Thr Thr Thr Val
              20                  25                  30        
 Lys Met Leu Leu Cys Glu Ala Leu Phe Gln Gly Thr Tyr Pro Gln Lys
          35                  40                  45            
 Val Tyr Cys Leu Pro Gly Val Val Pro Leu Thr His Asp Ile Gln Ile
      50                  55                  60                
 Ser Ile Val Ile Leu Arg Ile Phe Lys Cys Leu Arg Ile Val Lys Leu
  65                  70                  75                  80
 Trp Gln Ile Gln Leu Leu Gln Asn Pro Thr Val Ser Phe Glu Gly Pro
                  85                  90                  95    
 Ser Ser Leu Gly Asp Gly Ile Ser Ser Pro Thr Leu Glu Glu Pro His
             100                 105                 110        
 Lys Ser Gln Ser His Leu Gly Asn Leu Pro Asn Pro Gly Glu Met Leu
         115                 120                 125            
 Asp Asp Val Cys Leu Gln Asn Leu Asn Gln Ser Thr Val Phe Pro Asn
     130                 135                 140                
 Arg Glu Leu Arg Glu Gln Arg Glu Ala Gly Glu Glu Asp Arg Ser Leu
 145                 150                 155                 160
 Arg Asn Pro Arg Arg His Leu Gln Gly Trp Val Leu Pro Ser Pro Leu
                 165                 170                 175    
 Ser Pro Ser Pro Val Leu Phe His Gly Ala Ser Ala Glu His Ala Asp
             180                 185                 190        
 Lys Thr His Pro Ala Gly Asn Arg Trp His His Cys Trp Gln Thr Leu
         195                 200                 205            
 Glu Ala Phe Ala Ile Thr Asn Glu Asn Glu Gly Arg Cys Tyr Gln Ser
     210                 215                 220                
 Glu Ala Arg Arg Glu Arg Cys Glu Asp Asn Met Arg Gly Cys Arg Arg
 225                 230                 235                 240
 Thr Val Pro Val Gln Val Leu Glu Ile Lys Arg Leu Pro Ser Gln Lys
                 245                 250                 255    
 Tyr Cys Tyr Asp Ala Lys Arg Gly Pro Asn Leu Leu Ser Pro Thr Pro
             260                 265                 270        
 Ala Lys Leu Leu Tyr Trp Cys Leu Met Gly Gly Lys Arg Ile Ile Leu
         275                 280                 285            
 Thr Arg Ser Pro Gly Thr Trp Asp Leu Val Leu Ala Leu His Leu Cys
     290                 295                 300                
 Leu Gly Asn Thr Arg Leu Ala Gly Glu Ala Lys Ser Thr Ala Thr Arg
 305                 310                 315                 320
 Leu Phe Leu Ile Leu Ala Pro Pro Ala Pro Ala Gln His Pro Thr Glu
                 325                 330                 335    
 His Ala Gly Cys Val Gln
             340        



      <210> 1629
      <211> 193
      <212> PRT
      <213> Homo sapiens


      <400> 1629
 Met Trp Thr Ile Phe Gly Trp Ile Leu Glu Leu Leu Leu Thr Gly Leu
   1               5                  10                  15    
 Ala Asn Glu Leu Asp Val Lys Val Lys Lys Glu Thr Ser Lys Glu Ile
              20                  25                  30        
 Ser Lys Gly Pro Gln Lys Pro Leu Gly Tyr Gln Phe Cys Pro Leu Gln
          35                  40                  45            
 Ala Val Gly Gly Gly Glu Phe Gly Leu Thr Arg Val His Val Pro Phe
      50                  55                  60                
 Ser Phe Ser Asp Leu Lys Gln Ile Lys Ala Asp Leu Gly Lys Phe Ser
  65                  70                  75                  80
 Glu Asp Pro Asp Ser Tyr Ile Asp Val Leu His Gly Leu Gly Gln Asn
                  85                  90                  95    
 Phe Asp Leu Thr Trp Arg Asp Val Met Leu Leu Leu Asp Gln Thr Leu
             100                 105                 110        
 Ala Phe Asn Glu Lys Asn Val Ala Leu Ala Ala Ala Arg Glu Phe Gly
         115                 120                 125            
 Asp Thr Trp Tyr Leu Ser Gln Val Asn Asp Arg Met Thr Ala Lys Glu
     130                 135                 140                
 Arg Asp Lys Phe Pro Thr Gly Gln Gln Ala Ile Leu Ser Met Asp Ser
 145                 150                 155                 160
 His Trp Asp Leu Asp Ser Asp His Gly Asp Trp Ser Arg Lys His Leu
                 165                 170                 175    
 Leu Thr Cys Val Leu Glu Gly Leu Arg Ile Ile Arg Glu Lys Ala Met
             180                 185                 190        
 Asn
    



      <210> 1630
      <211> 211
      <212> PRT
      <213> Homo sapiens


      <400> 1630
 Met Asp Thr Ser Pro Leu Cys Phe Ser Ile Leu Leu Val Leu Cys Ile
   1               5                  10                  15    
 Phe Ile Gln Ser Ser Ala Leu Gly Gln Ser Leu Lys Pro Gly Leu Gly
              20                  25                  30        
 Ile Ile Pro Gln Leu Gly Thr Leu Gly Val Leu Leu Phe Met Pro Trp
          35                  40                  45            
 Pro Pro Pro Leu Cys Arg Ile Glu Gly Leu Pro Phe Leu Arg Leu Met
      50                  55                  60                
 Ile Gly Lys Val Leu Lys Gln Glu Glu Leu Gln Glu Gly Thr Arg Ala
  65                  70                  75                  80
 Pro Gly Thr Ala Glu Ile Asn His Gly Ser Leu Arg Glu Thr Leu Gly
                  85                  90                  95    
 Glu Lys Arg Asp Pro Asp Leu Glu Leu Lys Asp Leu Gly Leu Ser Pro
             100                 105                 110        
 Ser Ser Ile Thr Ser Gln His Val Ala Leu Asn Lys Ser Leu Lys Ala
         115                 120                 125            
 Cys Arg Pro Arg Ser Val Ile Ser Lys Glu Lys Ile Thr Ile Ile Glu
     130                 135                 140                
 Thr Pro Leu Gly Cys Phe Glu Gly Glu Met Arg Pro His Gly Tyr Ser
 145                 150                 155                 160
 Asp Ala Ser Leu Arg Ala Pro His Ala Gln Leu Leu His Ala Ser Ala
                 165                 170                 175    
 Thr Met Gln Pro Ile Trp Ile Met Asp Cys Tyr Glu Ala Cys Trp Gln
             180                 185                 190        
 Pro Ser Ile Arg Thr Lys Leu Tyr Ala His Trp Val Val Phe Ala Arg
         195                 200                 205            
 Met Leu Cys
     210    



      <210> 1631
      <211> 224
      <212> PRT
      <213> Homo sapiens


      <400> 1631
 Met Gly Ala Asp Pro Leu Trp Leu Gly Ala Val Leu Thr Ile Val Arg
   1               5                  10                  15    
 Leu Lys Glu Val Ser Pro Leu Pro Leu Asn Leu Lys Arg Leu Tyr Lys
              20                  25                  30        
 Glu Thr Leu Glu Ile Glu Pro Ile Leu Ile Ile Ile Ser Pro Gly Ala
          35                  40                  45            
 Asp Pro Ser Gln Glu Leu Gln Glu Leu Ala Asn Ala Glu Arg Ser Gly
      50                  55                  60                
 Glu Cys Tyr His Gln Val Ala Met Gly Gln Gly Gln Ala Asp Leu Ala
  65                  70                  75                  80
 Ile Gln Met Leu Lys Glu Cys Ala Arg Asn Gly Asp Trp Leu Cys Leu
                  85                  90                  95    
 Lys Asn Leu His Leu Val Val Ser Trp Leu Pro Val Leu Glu Lys Ser
             100                 105                 110        
 Pro Pro Gly Leu Lys Lys Asn Leu Met Arg Thr Tyr Glu Ser Trp Thr
         115                 120                 125            
 Pro Glu Gln Ile Ser Lys Lys Asp Asn Thr His Arg Ala His Ala Leu
     130                 135                 140                
 Phe Ser Leu Ala Trp Phe His Ala Ala Cys Gln Glu Arg Arg Asn Tyr
 145                 150                 155                 160
 Ile Pro Gln Met Arg Ile Ser Pro His Glu Pro Thr Pro Pro Gly Pro
                 165                 170                 175    
 Trp Val Arg Asn Thr Glu Leu Cys Gly Val Cys Thr Ala Ala Ala Gln
             180                 185                 190        
 Ser Phe Gln Arg Lys Glu Gln Ala Ala Ile Ser Ala Val Ser Gln Pro
         195                 200                 205            
 Ser Leu Val Met Pro Pro Asp Thr Gly Lys Ile Lys Ala Thr Arg Val
     210                 215                 220                





      <210> 1632
      <211> 250
      <212> PRT
      <213> Homo sapiens


      <400> 1632
 Met Met Leu Lys Ile Met Leu Val Val Val Met Val Val Ile Thr Leu
   1               5                  10                  15    
 Val Val Met Val Ile Met Val Val Val Val Gly Asp Asp Arg Gly Asp
              20                  25                  30        
 Asp Ser Gly Ser Gly Asp Gly Gly Gly Gly Ser Gly Asp Asp Gly Asn
          35                  40                  45            
 Ser Gly Arg Tyr Pro Thr Ser Cys Glu Thr Gln Arg Ser Cys Ser Ser
      50                  55                  60                
 Arg Ile Gln Arg Asn Leu Ala Gly Lys Glu Arg Pro Lys Ala Glu Pro
  65                  70                  75                  80
 Asn Gly Ala Arg Phe Tyr Gly Ser Val Ile Leu Cys Pro Asp Ala Ala
                  85                  90                  95    
 Gly Pro Ala Gly Glu Glu Ser Gln Met Val Ser Ile Lys Leu Met Phe
             100                 105                 110        
 Asp Ser Gly His Val Tyr Phe Gly Glu Leu His Glu His Leu Gly Leu
         115                 120                 125            
 Ala Ser Phe Pro Gln Ala Thr Pro Val Thr Cys Trp His Lys Ile Asn
     130                 135                 140                
 His Asn Ile Gln Thr Lys Gln Tyr Leu Gln Gly Ala Met Gly Pro Pro
 145                 150                 155                 160
 Arg Pro Ser Lys Ile Lys Val Pro Val Gly Gly His Ser Ala Ala Pro
                 165                 170                 175    
 Gln Val Arg Ile Val Ser Glu Leu Lys Asn Gly Ser Asn Trp Pro Lys
             180                 185                 190        
 Met Leu Lys Phe Ile Ala Gly Ile Thr Gly Thr Val Cys Ser Asn Leu
         195                 200                 205            
 Gly Gly Phe Ser Leu Arg Glu Ser Val Ala Ala Ala Phe Leu Leu Ile
     210                 215                 220                
 Glu Thr Thr Leu Ser Leu Gln Leu Arg Trp Gly Arg Phe Ser Tyr Leu
 225                 230                 235                 240
 Arg Ala Glu Arg Arg Leu Phe Gly Val Phe
                 245                 250



      <210> 1633
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 1633
 Met Ala Met Ser Ser Leu Thr Ser Arg Thr Val Gly Val Leu Cys Phe
   1               5                  10                  15    
 Gly Leu Gly Thr Pro Gln Leu Gln Ser Leu Pro Arg Thr Ala Ser Val
              20                  25                  30        
 Gly Gly Leu Pro Leu Ala Glu Leu Pro His Gly Ser Leu Glu Lys Glu
          35                  40                  45            
 Trp Val Val His Leu Lys Met Phe Pro His Pro Ser Gln Pro His Phe
      50                  55                  60                
 Ser Asp Asp Pro Ser Ile Gln Pro Asn Ser Arg Tyr Ser Gly Asn Thr
  65                  70                  75                  80
 Asn Ile Asn Ser Val Arg Ala Ser Cys Pro Leu Leu Pro Arg Cys Ser
                  85                  90                  95    
 Glu Ser His Thr Gly Leu Leu Glu Ser Glu Pro Ala Arg Ala
             100                 105                 110



      <210> 1634
      <211> 91
      <212> PRT
      <213> Homo sapiens


      <400> 1634
 Met Ala Val Lys Leu Leu Val Phe Ile Val Ile Val Asn Cys Leu Phe
   1               5                  10                  15    
 Ser Arg Leu Leu Gln Asn Trp Lys Lys Gly Gly Cys Glu Trp Asp Lys
              20                  25                  30        
 Leu Leu Tyr Asn Ala Met Lys Phe Thr Val Val Thr Lys Asn Gln Ser
          35                  40                  45            
 Val Phe Leu Asn Lys Leu Phe Leu Asp Ser Cys Lys Pro Leu Val Asn
      50                  55                  60                
 Phe Gln Ser Pro Glu Lys Val Asp Ser Asp Ile Ser Val Ser Phe Leu
  65                  70                  75                  80
 Phe Phe Leu Asn Glu Lys Tyr Lys Gln Tyr Thr
                  85                  90    



      <210> 1635
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 1635
 Met Gly Ala Thr Phe Trp Leu Leu Val Gly Leu Val Ser Pro Val Val
   1               5                  10                  15    
 Ser Tyr Leu Ile Ala Leu Thr Asp Leu Thr Leu Glu Ile Leu Ser Leu
              20                  25                  30        
 Gln Gly Pro Cys Arg Arg Trp Asp Leu Pro Gln Arg Met Pro Gln Gly
          35                  40                  45            
 Met Phe Leu Leu Gly Ala Lys Gln Ser Phe Ser Gln Ile Leu Glu Arg
      50                  55                  60                
 Lys Leu Leu Gly Ser Cys Leu
  65                  70    



      <210> 1636
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1636
 Met Ala Arg Asn Arg Gly Phe Leu Ser Ala Val Phe Cys Phe Thr Ala
   1               5                  10                  15    
 Pro Ser Gly Thr Asp Glu Arg Gly Ala Thr Val Trp Leu Pro Pro His
              20                  25                  30        
 Leu Thr His Leu Ser Ala Gln Asp Gly Ser Lys Ala Gln Glu Thr His
          35                  40                  45            
 Trp Thr Arg Glu Glu Val Leu Ile Cys Glu Gly Gln Pro Ala Thr Thr
      50                  55                  60                
 Leu Thr Val Gly Asn Leu Ala Glu Asp Ser Pro Arg Tyr Ser Pro Asp
  65                  70                  75                  80
 Arg Leu
        



      <210> 1637
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1637
 Met Ala Tyr Leu Ser Lys Glu Ile Asp Val Val Ala Lys Gly Trp Pro
   1               5                  10                  15    
 His Cys Leu Trp Val Val Val Ala Val Ala Val Leu Val Ser Glu Ala
              20                  25                  30        
 Val Lys Ile Leu Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp
          35                  40                  45            
 Val Asn Gly Ile Leu Thr Ala Lys Gly Asp Leu Cys Gln Arg Thr Phe
      50                  55                  60                
 Val Ser Ser Arg Ile Glu Ala Val Lys Leu Gln Ile Val Pro Gln Met
  65                  70                  75                  80
 Glu Pro Gln Met Gln Pro Met Thr Lys Ile Tyr Cys Gly Ser Leu Asp
                  85                  90                  95    
 Trp Pro Ala Ser Pro Cys Ser Asn Val Asn Asp Ile Glu Gly Thr Pro
             100                 105                 110        
 Pro Glu Glu Ile Ser Thr Ala Gln Pro Leu Leu Cys Pro Asn Ser Ala
         115                 120                 125            
 Gly Ser Ser
     130    



      <210> 1638
      <211> 227
      <212> PRT
      <213> Homo sapiens


      <400> 1638
 Met Ser Tyr Ser Cys Pro Ser Leu Pro Ser Pro Gly Ser Phe Thr Cys
   1               5                  10                  15    
 Leu Leu Leu Leu Val Val Lys Leu Lys Gln Thr Val Leu Pro Gly Leu
              20                  25                  30        
 Arg Ala Leu Gly Leu Gly Arg Gly Gln Ser Gly His Gln Pro Asn Trp
          35                  40                  45            
 Trp Phe Gly Met Leu Val Pro Glu Ile Trp Pro Val Ser Arg Thr Gly
      50                  55                  60                
 Ser Gly Ala Gln Ala Val Ala Asp His Val Val Gln Val Leu Phe Cys
  65                  70                  75                  80
 Phe Ser Gly Arg Ser Ala Glu Trp Glu Glu Leu Trp Val Leu Pro Arg
                  85                  90                  95    
 Arg Thr Leu Trp Gln His Arg Ser Glu Lys Lys Lys Ser Ser Glu Ala
             100                 105                 110        
 Ala Glu Glu Asp Leu Arg Thr Met Glu Glu Gln Val Arg Gly Thr Trp
         115                 120                 125            
 Gly Glu Thr Val Gln Gly Gly Ser Lys Gly Gly Glu Arg Asn Gly Ala
     130                 135                 140                
 Thr Ser Glu Ser Glu Glu Asp Asn Glu Leu Asp Cys Asp Pro Leu Arg
 145                 150                 155                 160
 Glu Ser Gln Gly Pro Gln His Ser Glu Arg Met Gly Ser His Ser Arg
                 165                 170                 175    
 Ala Pro Gly Cys Ala Phe Thr His Cys Ile Pro Glu Glu Pro Ser Thr
             180                 185                 190        
 Ser Thr Arg Arg Arg Lys Thr Glu Gly Lys Val Pro Ser Leu Met Lys
         195                 200                 205            
 Phe Ser Leu Asp Pro Thr Thr Ala Tyr Glu Glu Tyr Leu His Tyr Ala
     210                 215                 220                
 Val Lys Leu
 225        



      <210> 1639
      <211> 276
      <212> PRT
      <213> Homo sapiens


      <400> 1639
 Met Ala Tyr Lys Val Val Trp Ala Cys Ala Arg Ala Leu Met Ala Trp
   1               5                  10                  15    
 Gly Gly Ile His Ile Leu Tyr Asn Gly His Gly Ala Ala Leu Arg Gly
              20                  25                  30        
 His His His Gln Gly Ser Ala Leu Asp Pro Pro Cys Ser Cys Pro Leu
          35                  40                  45            
 Leu Ala Ser Pro Leu Leu Cys Ser Ala Arg Lys Leu Ser Pro Val Ala
      50                  55                  60                
 Gly Leu Leu Gln Val Leu Asn Gln Leu Pro Phe Ala Glu Trp Pro Val
  65                  70                  75                  80
 Glu Gly Ser Asp Pro Ser Asp Tyr Val Ala Phe Pro Gly Thr Pro Ser
                  85                  90                  95    
 Leu Leu Gly Ala Gln Ala Pro Trp Ile Val Lys Ala Gly Gly Ala Ala
             100                 105                 110        
 Gln Ser Ile Pro Pro Arg Thr Ser Arg Tyr Gly Gln Gln Arg Ala Ala
         115                 120                 125            
 Asn Cys His Leu Arg Ala Pro His Pro Gly Arg Pro Arg Gly Leu Asn
     130                 135                 140                
 Leu Ala Leu Ser Thr Trp Gly Glu Arg Gly Gly Arg Arg Val Val Leu
 145                 150                 155                 160
 Val Val Cys Val Phe Leu Ile Ile Glu Asn Gln Lys Pro Asp Thr Leu
                 165                 170                 175    
 Ser Thr Thr Ser Gly Asp Val Leu Cys Gly Ile Phe Cys Pro Cys Gly
             180                 185                 190        
 Val Gln Pro Ser Ile Leu Lys Gln Ser Ser Ser Phe Asp Leu Asp Ser
         195                 200                 205            
 Thr Asn Ser Tyr Ala Met Ser Thr Leu Leu Ser Leu Asp Leu Ser Thr
     210                 215                 220                
 Glu Glu Pro Asn Leu Arg Val Leu Gly Asp Trp Gln Ala Gln Gly Glu
 225                 230                 235                 240
 Arg Pro Leu Leu Val Gly Thr Glu Thr Glu His Leu Gln Ala Pro Glu
                 245                 250                 255    
 Leu Ser Pro Ala Arg Ser Leu Leu Gln Ser Cys Thr Gly Ser His Val
             260                 265                 270        
 Pro Ala Gln Met
         275    



      <210> 1640
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 1640
 Met Ala Leu Ala Arg Ala Ala Ile Leu Leu Leu Pro Leu Ala Ser Val
   1               5                  10                  15    
 Glu Lys Ala Ser Cys Phe Arg Phe Thr Ile Ser Met Asn Glu Glu Lys
              20                  25                  30        
 Val Ala Arg Phe Gln Ala Gln Ile Gln Asn Gly Asp Lys Gly Lys Lys
          35                  40                  45            
 Pro Asn Val His Asn Ser Pro Lys Ala Lys Ile Glu Phe Phe Gln Tyr
      50                  55                  60                
 Arg Cys Tyr Thr Arg Asp Trp Pro Gln Pro Val Ala Phe Asn Tyr Gln
  65                  70                  75                  80
 Gln Ser Thr Arg Lys Trp Pro Leu Lys Asp Arg Lys Ser Lys Gly Leu
                  85                  90                  95    
 Gly Leu Lys Pro Val Gly Gly Ala Arg Glu Leu Ser Gly Thr Ile Lys
             100                 105                 110        
 Glu Ile Leu Gly Thr Ala Gln Ser Val Gly Cys Asn Val Asp Gly His
         115                 120                 125            
 Tyr Pro His Asp Ile Ile Asp Asp Ile Asn Ser Gly Ala Val Glu Cys
     130                 135                 140                
 Pro Ala Ser
 145        



      <210> 1641
      <211> 336
      <212> PRT
      <213> Homo sapiens


      <400> 1641
 Met Ala Val Ala Thr Ala Ala Ala Val Leu Ala Ala Leu Gly Gly Ala
   1               5                  10                  15    
 Leu Trp Leu Ala Ala Arg Arg Phe Val Gly Pro Arg Val Gln Arg Leu
              20                  25                  30        
 Arg Arg Gly Gly Asp Pro Gly Leu Met His Gly Lys Thr Val Leu Ile
          35                  40                  45            
 Thr Gly Ala Asn Ser Gly Leu Gly Arg Ala Thr Ala Ala Glu Leu Leu
      50                  55                  60                
 Arg Leu Gly Ala Arg Val Ile Met Gly Cys Arg Asp Arg Ala Arg Ala
  65                  70                  75                  80
 Glu Glu Ala Ala Gly Gln Leu Arg Arg Glu Leu Arg Gln Ala Ala Glu
                  85                  90                  95    
 Cys Gly Pro Glu Pro Gly Val Ser Gly Val Gly Glu Leu Ile Val Arg
             100                 105                 110        
 Glu Leu Asp Leu Ala Ser Leu Arg Ser Val Arg Ala Phe Cys Gln Glu
         115                 120                 125            
 Met Leu Gln Glu Glu Pro Arg Leu Asp Val Leu Ile Asn Asn Ala Gly
     130                 135                 140                
 Ile Phe Gln Cys Pro Tyr Met Lys Thr Glu Asp Gly Phe Glu Met Gln
 145                 150                 155                 160
 Phe Gly Val Asn His Leu Gly His Phe Leu Leu Thr Asn Leu Leu Leu
                 165                 170                 175    
 Gly Leu Leu Lys Ser Ser Ala Pro Ser Arg Ile Val Val Val Ser Ser
             180                 185                 190        
 Lys Leu Tyr Lys Tyr Gly Asp Ile Asn Phe Asp Asp Leu Asn Ser Glu
         195                 200                 205            
 Gln Ser Tyr Asn Lys Ser Phe Cys Tyr Ser Arg Ser Lys Leu Ala Asn
     210                 215                 220                
 Ile Leu Phe Thr Arg Glu Leu Ala Arg Arg Leu Glu Gly Thr Asn Val
 225                 230                 235                 240
 Thr Val Asn Val Leu His Pro Gly Ile Val Arg Thr Asn Leu Gly Arg
                 245                 250                 255    
 His Ile His Ile Pro Leu Leu Val Lys Pro Leu Phe Asn Leu Val Ser
             260                 265                 270        
 Trp Ala Phe Phe Lys Thr Pro Val Glu Gly Ala Gln Thr Ser Ile Tyr
         275                 280                 285            
 Leu Ala Ser Ser Pro Glu Val Glu Gly Val Ser Gly Arg Tyr Phe Gly
     290                 295                 300                
 Asp Cys Lys Glu Glu Glu Leu Leu Pro Lys Ala Met Asp Glu Ser Val
 305                 310                 315                 320
 Ala Arg Lys Leu Trp Asp Ile Ser Glu Val Met Val Gly Leu Leu Lys
                 325                 330                 335    





      <210> 1642
      <211> 200
      <212> PRT
      <213> Homo sapiens


      <400> 1642
 Met Gln Val Met Thr Leu Leu Cys Leu Ala Phe Val Ile Gly Ile Lys
   1               5                  10                  15    
 Ser Ser Ala Lys Glu Thr Pro Pro Arg Trp Asn Phe Lys His Gln Arg
              20                  25                  30        
 Lys Gly Arg Gly Asn Phe Arg Asp Gly Arg Val Gln Val Leu Tyr Cys
          35                  40                  45            
 Lys Val Gly Val Trp Ser Leu Asp Phe Gln Ala Thr Glu Ala Gln Phe
      50                  55                  60                
 Tyr Pro Gln Ile Lys Val Leu Gly Pro Ser Ser Phe Thr Ser Pro Asp
  65                  70                  75                  80
 Ile Leu Thr Leu Asn Phe Leu Thr Ile Leu Asp Val Phe Asp Ala Phe
                  85                  90                  95    
 Lys Asp Pro Pro Asn Ile Ile Arg Asp Gly Arg Pro Val Phe Arg Leu
             100                 105                 110        
 Ser Gln Ser Gly Gln Leu Glu Phe Leu Leu Glu Val Gly Val Leu Lys
         115                 120                 125            
 Val Thr Lys Leu Ala Asp Ser Ser Ser Ser Ser Ser Ser Arg Thr Glu
     130                 135                 140                
 Glu Pro Ala His Met Pro Asn Pro Leu Pro Pro Ile Leu Ala Ser Glu
 145                 150                 155                 160
 Gln Ala Thr Leu Glu Ala Gln Glu Ser Ala Cys Leu Asp Leu Leu Thr
                 165                 170                 175    
 Leu Val Thr Val Asp Thr Ile Leu Gly Ser Lys Asn Arg Asp Ala Trp
             180                 185                 190        
 Pro Ser Thr Ala Thr Thr Gly Gly
         195                 200



      <210> 1643
      <211> 255
      <212> PRT
      <213> Homo sapiens


      <400> 1643
 Met Leu Leu Phe Thr Lys Ser Ser Trp Gln Leu Ser Leu Cys Asn Ala
   1               5                  10                  15    
 Phe Glu Ser Thr Leu Ser Pro Lys Tyr Ser Tyr Trp Gly Thr Gly Val
              20                  25                  30        
 Ser Gly Asp Ser Ser His Ser Leu Ala Thr Ala Ser Arg Ser Asn Ser
          35                  40                  45            
 Ala Leu Ser Cys Gly Tyr Ala Leu Gly Val Ala Asp Ala Ala Gly Ser
      50                  55                  60                
 Ala Gly Gly Ala Leu Trp Gln Arg Glu Gly Ile Ala His Arg Arg Cys
  65                  70                  75                  80
 Arg Trp Val His Gly Ser Val Leu Arg Gly Gly Arg Gly Val Ser Asn
                  85                  90                  95    
 Ala Lys Leu Arg Gln Gln Lys Gln Gln Pro Gln Arg Thr Gln Lys Pro
             100                 105                 110        
 Glu Leu Leu Gly Gly Gly Gly Trp Arg Asp Pro Glu Arg Gly Thr Ala
         115                 120                 125            
 Ala Gly Cys Pro Ala Val Gly Ala Pro Ala Arg Gln Gly His Gln Arg
     130                 135                 140                
 Ala Pro Trp Ser Ser Arg Asn Ala Ser Val Trp Glu Asp Ala Ile Ala
 145                 150                 155                 160
 Lys Arg Thr Trp Cys Ser Gly Ser Ile Cys Val Lys Glu Lys His Pro
                 165                 170                 175    
 Leu Leu Ser Arg Pro Gly Lys Gly Val Ser Leu Ser Pro Gly Glu Phe
             180                 185                 190        
 Arg Glu Asp Ser Thr Pro Pro Pro Leu Val Pro Ala Val Ile Arg Arg
         195                 200                 205            
 Pro Ile Leu Leu Pro Val Met Leu Cys Phe Ser Gly His Ala Ser Ser
     210                 215                 220                
 Pro Leu Ser Tyr Thr Ile Leu Tyr Thr Trp Leu Cys Leu Leu Asp Ser
 225                 230                 235                 240
 Thr Ser Lys Leu Val Lys Val Leu Lys Val Ser Asp Met Gln Lys
                 245                 250                 255



      <210> 1644
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1644
 Met Lys Gly Asn Ser Glu Gln Cys Leu Leu Leu Cys Thr Leu Gly Arg
   1               5                  10                  15    
 Thr Val Val Ala Thr Leu Tyr Thr Arg Thr Asn Cys Gly Cys Cys Leu
              20                  25                  30        
 Gln Gly Asp Glu Gln Leu Ile Cys Ile Glu Arg Leu Leu Arg Gln Val
          35                  40                  45            
 Ala Cys Leu Leu Asp Glu Leu Cys Thr Asp Leu Arg Glu Asp Leu Asn
      50                  55                  60                
 Ser Tyr Arg Ser Cys Gly Asp Leu Ile Ile His Ser His Ile Val
  65                  70                  75                



      <210> 1645
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1645
 Met Leu Leu Val Val Leu Gly Pro Gly Ile Gly Leu Gln Leu Ser Leu
   1               5                  10                  15    
 Val Glu Glu Val His Val Leu Ala Gln Arg Arg Ala Met Gln Leu Ser
              20                  25                  30        
 Leu Gly Asp Val Val His Val Val Val Ser Glu Cys Val Leu Arg Leu
          35                  40                  45            
 Leu Asp Gly Leu Gln Phe Pro Met Gln Ile Gln Cys Phe Phe Cys Phe
      50                  55                  60                
 Phe Gly Ser Ala Thr Trp Asn Leu Tyr Val Gln Asp Gly Ala Ile Ser
  65                  70                  75                  80
 Ala Met Thr Thr Glu Asn Val Pro Leu Ser His Glu Glu Glu Gly Val
                  85                  90                  95    
 Gly Val Thr Glu Ile Gln Ile Thr Ala Tyr Ala Ala Ala Ala Ser Leu
             100                 105                 110        
 Gly Leu Ala Thr Gln Trp Gly Cys Arg Thr Pro Cys Trp Cys Ser Arg
         115                 120                 125            
 Met Ser Ala Met Asp Pro Val Ile
     130                 135    



      <210> 1646
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 1646
 Met Trp Trp Ala Asp Ile Leu Gly Leu Leu Leu Leu Thr Cys Leu Val
   1               5                  10                  15    
 His Cys Met Gln Ile Lys Ser Asp Ala Gln Ser Ser Arg Leu Pro Asn
              20                  25                  30        
 Ala Gln Tyr Trp Glu Glu Arg Asn Lys Glu Ser Lys Ala Asn Gln Val
          35                  40                  45            
 Asn Met Leu Pro Trp Lys Lys Arg Val Cys Tyr Gln Glu Phe Tyr Ala
      50                  55                  60                
 Ser Gly Ser Ile Glu Val His Arg Val Ser His Trp Gln His Leu Asp
  65                  70                  75                  80
 Leu Gly Glu Ala Thr Phe Lys Gln Gln Gln Gln Gln Gln Gln
                  85                  90                



      <210> 1647
      <211> 240
      <212> PRT
      <213> Homo sapiens


      <400> 1647
 Met Ala Val Phe Ile Ser Arg Cys Ala Leu Thr Ala Ser Leu Ala Cys
   1               5                  10                  15    
 Ser Phe Thr Leu Leu Ala Val Ser Pro Val Ile Ser Glu Ala Pro Ile
              20                  25                  30        
 Tyr Leu Ala Tyr Leu Glu Ser Met Arg Ser Gly Gln Asp Leu Ser Phe
          35                  40                  45            
 Phe Met Gly Ser Glu Gln Arg Ala Gly Pro Ser Ala Gly Asn Ala Leu
      50                  55                  60                
 Met Asp Ala Ile Glu Val Ala Met Asp Gln Val Pro Gly Glu Glu Thr
  65                  70                  75                  80
 Glu Ala Lys Gln Gly Gln Ser Ala Leu Gln Arg Arg His Ser Gln Arg
                  85                  90                  95    
 Ala Ala Ala Ala Leu Leu His Cys Lys Ala Gln Ala Glu Ala Ser Ser
             100                 105                 110        
 Ala Ala Lys Trp Ser Ser His Lys Asn His Asp Ala Gly Ser Glu Gly
         115                 120                 125            
 Thr Ile Gln Thr Ala Ser Thr Lys Leu His Val His Pro Val Cys Pro
     130                 135                 140                
 Ser Glu Ala Leu Ala Ile Ala Cys Trp Asn Arg Thr Thr Gln Phe Thr
 145                 150                 155                 160
 Asp Arg Ser Ser Pro Arg Leu Lys Pro Ile Leu Leu Ile Lys Val Pro
                 165                 170                 175    
 Ala Lys Pro Asp Leu Val Ala Thr Leu Ser Gln Tyr Ala Gln Val Leu
             180                 185                 190        
 Leu Met Gly Ile Asp Val Ser Tyr Leu Lys Glu Pro Pro His Phe His
         195                 200                 205            
 Arg Ala Ala Pro His Val Ala Thr Pro Ser Ile Ser Gln Val Ser Thr
     210                 215                 220                
 Thr Leu Leu Pro Asp His Ala Ala Ala Ala Gln Glu Pro Val Lys Thr
 225                 230                 235                 240





      <210> 1648
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 1648
 Met Ser Leu Thr Val Pro Phe Ile Thr Ala Ile Pro Thr Leu Ile Cys
   1               5                  10                  15    
 Glu Val Thr Asn Ala Val Arg Arg Gln Gly Asp Ser Ile Val Thr Leu
              20                  25                  30        
 Lys Ala Phe Cys Pro Leu Leu Ser Gln Cys Arg Ile Glu Asn Thr Gly
          35                  40                  45            
 Asn Pro Lys Ala Thr Lys Ser Phe Ile His Gly Glu Cys Gln His Ser
      50                  55                  60                
 Val Gln Glu Glu Glu His Tyr Leu His Lys Asn Ser Pro Val Asn Ser
  65                  70                  75                  80
 Ser Arg Phe Thr Phe Thr Ser Glu Thr Pro Asp Phe Arg Met His Ile
                  85                  90                  95    
 Gln Asn Glu Gln Tyr Ile Glu Val Glu Ile Thr Gln Thr
             100                 105                



      <210> 1649
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 1649
 Met Leu Pro Pro Ser Leu Gly Leu Tyr Gln Ser Asn Tyr Leu Ala Leu
   1               5                  10                  15    
 Cys Leu Leu Tyr Thr Cys Tyr Ala Ala Pro Ser Arg Asp Val Tyr Ser
              20                  25                  30        
 Arg Ser Leu Pro Glu Leu Thr Ser Glu Leu Ser Glu Ser Ser Glu Thr
          35                  40                  45            
 Ser Ile Ser Glu Lys Ser Asp Ser Ser Asn Glu Ser Ser Ala Lys Asn
      50                  55                  60                
 Ser Ser Arg Met Met Leu Thr Ser Arg Val Gly Met Leu Arg Phe Leu
  65                  70                  75                  80
 Gly Leu Asp Ile Leu Ser Asp
                  85        



      <210> 1650
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 1650
 Met Trp Asn Leu Pro Pro Tyr Ser Val Ile Leu Lys Val Tyr Thr Leu
   1               5                  10                  15    
 Ala Thr Thr Ile Ala Phe Ala Gln Tyr Ser Gln His Lys Pro Ser Leu
              20                  25                  30        
 Asp Arg Asn Glu Thr Ala Asp Leu Gln Ala Ala Leu Leu His
          35                  40                  45    



      <210> 1651
      <211> 84
      <212> PRT
      <213> Homo sapiens


      <400> 1651
 Met Thr Arg Ser Arg Ser Leu Arg Ala Ala Ile Leu Ala Pro Arg Leu
   1               5                  10                  15    
 Arg Leu Leu Leu Gly Trp Gln Pro Leu His Ser Gly Tyr Ser Pro Gly
              20                  25                  30        
 Ser Phe Leu Leu Pro Gly Pro Gly Thr Ala Thr Ser Ala Ser Ala Pro
          35                  40                  45            
 Leu Arg Arg Asp Pro Leu Arg Gln Leu Asp Thr Arg Arg Arg Phe Pro
      50                  55                  60                
 Lys Gly Gly Ile Gly Gly Leu Ala Gly Arg Gly Arg Asp Lys Arg Arg
  65                  70                  75                  80
 Gly Leu Val Ala
                



      <210> 1652
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1652
 Met Gln Cys Cys Leu Leu Leu Arg Trp Leu Ala Ser Ala Leu Leu Arg
   1               5                  10                  15    
 Leu Leu Gly Ala Ala Thr Glu Lys Arg Glu Arg Val Lys Arg Ala Glu
              20                  25                  30        
 Thr Gly Cys Cys His His Thr Thr Glu Gly Gly Pro Gly Ala Gln Pro
          35                  40                  45            
 Ala Glu Gly Leu Arg Asp Arg Trp Glu Gln Asp Pro Thr Thr Arg Pro
      50                  55                  60                
 Met Glu Glu Glu Val Gly Arg Ser Gln Lys Gly Glu Glu Lys Glu Arg
  65                  70                  75                  80
 Lys Gly Gly Glu Leu Asn Glu Lys Gly Gly Arg Val Glu Lys Val Leu
                  85                  90                  95    
 Ser Ser Phe Arg Ser Thr Val Glu Gln Cys Ser Ser Trp Ser Thr Asn
             100                 105                 110        
 Cys Leu Asp Phe Ile Leu Ala
         115                



      <210> 1653
      <211> 154
      <212> PRT
      <213> Homo sapiens


      <400> 1653
 Met Ala Cys Trp Val Asn Gly Leu Leu Ala Cys Gln Cys Leu Ser Val
   1               5                  10                  15    
 Cys Phe Pro Ala Ser Val Leu Leu Trp Lys Pro Ser Asp Tyr Gln Pro
              20                  25                  30        
 Leu Val Ser Ser Ser Ala Lys Leu Thr Leu Glu Asn Pro Phe Leu Asn
          35                  40                  45            
 Met Asp Leu Gln Cys Thr Gly Ser Glu Met His Cys Leu Phe Ile Lys
      50                  55                  60                
 Val Leu His Phe Cys Ser Cys Leu Cys Pro Glu Leu Arg Asn Arg Arg
  65                  70                  75                  80
 Ser Thr Ala Asp Asn Leu Glu Trp Asn Lys Gly Asp Val Phe Glu Ala
                  85                  90                  95    
 Leu Pro Leu Glu Asp Val Leu Gly Arg Ser Pro Ala Gln Gln His Ala
             100                 105                 110        
 Ala Gly Pro His Leu Gly Arg Asp Phe Leu Ile Ser Lys Ser Leu Gly
         115                 120                 125            
 Glu Ile Gly Glu Arg Ile Glu Ile Ser Thr Lys Glu Cys Leu Ile Tyr
     130                 135                 140                
 Glu Leu Met Leu Asn Leu His Leu Thr Asp
 145                 150                



      <210> 1654
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 1654
 Met Gln Trp Ile Thr Val Ile Val His Phe Gln Cys Leu Leu Pro Pro
   1               5                  10                  15    
 Ser Thr Lys Tyr Glu Leu His Ala Trp Leu Ile Tyr Asp Phe Gly Tyr
              20                  25                  30        
 Tyr Arg Phe Met Cys Val Val His Tyr Phe Val Thr Val Ile Lys Val
          35                  40                  45            
 Lys Tyr
      50



      <210> 1655
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 1655
 Met Ala Gly His Ser Leu Phe Leu Glu Ile Lys Phe Tyr Trp Asn Thr
   1               5                  10                  15    
 Ala Thr Leu Ile Cys Leu Leu Ile Val Tyr Gly Cys Phe His Pro Thr
              20                  25                  30        
 Arg Ala Glu Leu Ser Ser Cys Asp Ile Ala Arg Trp Pro Ala Lys Pro
          35                  40                  45            
 Lys Ile Phe Thr Asn Trp Cys Pro Lys Asn Lys Phe Ala Asn Pro Leu
      50                  55                  60                
 Thr Ile Arg Ser Ser Ser Pro Ser Tyr Thr Val Gln Lys Cys Asn Thr
  65                  70                  75                  80
 Ile Thr Tyr Thr Asn Asn Ala Gly Pro Arg Val Ser Thr Lys Glu Asp
                  85                  90                  95    
 Leu Thr Gln Pro Asp Arg Trp Gly Tyr Pro Ser Cys Ala Gly Phe Arg
             100                 105                 110        
 Ala Asn Lys Arg Leu Glu Lys Glu Met Leu Ala Thr Ile Leu Asp Ser
         115                 120                 125            
 Thr Glu Asp Glu Asn Asn Pro Gln Ala Leu Phe Asp Ser Thr Phe Ser
     130                 135                 140                
 Ser Thr Ile Thr Cys Ala Ala Tyr Cys Ile Gln Glu Ile
 145                 150                 155        



      <210> 1656
      <211> 51
      <212> PRT
      <213> Homo sapiens


      <400> 1656
 Met Thr Val Gln Lys Ala Leu Ser Ala Phe Leu Ile Val Leu Thr Cys
   1               5                  10                  15    
 Gly Ser Ser Phe Leu Glu Val Trp Glu Lys Gln Ser Lys Pro Asp Glu
              20                  25                  30        
 Lys Arg Leu Trp Ile Ser Gln Leu Phe Arg Glu Gln Val Gln Met Ala
          35                  40                  45            
 Phe Met Asn
      50    



      <210> 1657
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 1657
 Met Thr Ser Ile Leu Leu Phe Ile Tyr Asp Trp Ile Pro Gly Leu Val
   1               5                  10                  15    
 Ala Thr Cys Trp Ile Ala Pro Asp Leu Val Ala Pro His Trp Lys Val
              20                  25                  30        
 Leu Ser Arg Val His Gln Ala Ser Val Gly Ile Val Glu Val Asn Pro
          35                  40                  45            
 Thr Ser Arg Ile Asp Gly Phe Ala Glu Ile Trp Thr Val Pro Met Asn
      50                  55                  60                
 Pro Leu Lys Val Leu Leu Leu Gln Trp Ser Leu Phe Thr Cys Tyr Ser
  65                  70                  75                  80
 Arg Gly Gly
            



      <210> 1658
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1658
 Met Val Cys Pro Glu Pro His Pro Ala Leu Cys Lys Pro Gln Pro Cys
   1               5                  10                  15    
 Ser Val Ala Phe Leu Ala Leu His Ala Leu Gln Arg Phe Thr Trp Leu
              20                  25                  30        
 Leu Ala His Val Thr Cys Ser Cys Phe Val Thr Glu Thr Leu Phe Ser
          35                  40                  45            
 Val Gly Thr Glu Tyr Ala Asn Val Tyr Leu Ser Pro His Lys His Pro
      50                  55                  60                
 Ser Ser Gln Arg Ala Ala Gly Asp Ser His Asn Ser Lys Ser Ala Val
  65                  70                  75                  80
 Glu Val Ile Thr Ser Thr Val Glu Asp Ser His Leu Trp Lys Gly Phe
                  85                  90                  95    
 Gly Val Asp Val Ser His Ser
             100            



      <210> 1659
      <211> 239
      <212> PRT
      <213> Homo sapiens


      <400> 1659
 Met Val Cys Ile Leu Ser Leu Leu Ile Arg Leu Ser Leu Asp Glu Gln
   1               5                  10                  15    
 Thr Cys Ala Leu Thr Ser Ser His Ile Gln Glu Trp Gly Pro Lys Arg
              20                  25                  30        
 Glu Ile Arg Arg Lys Arg Pro Leu Pro Thr Lys Phe Ser Gly Ala Asp
          35                  40                  45            
 Asn Asp Lys Asn Ser Ser His Lys Arg Ser Ala Ser Ile Thr Lys Pro
      50                  55                  60                
 Leu Ser Gln Pro Ser Thr Leu Pro Arg Asp Val Arg Arg Pro Pro Ser
  65                  70                  75                  80
 Gly His Arg Leu Pro Asn Asp Phe Gly Cys Pro Gly Pro Ala Pro Glu
                  85                  90                  95    
 Pro Arg Thr Pro Pro Ala Ser Phe Arg Lys Leu Arg Thr Tyr Pro Ala
             100                 105                 110        
 Ala Thr Leu Ser Thr Ala Thr Ala Ala Asp Ser Ala Phe Leu Leu Pro
         115                 120                 125            
 Arg Lys Cys Ser Phe Ser Ala Glu Ala Cys Arg Cys Val Arg Glu Asn
     130                 135                 140                
 Phe Arg Val Lys Pro Pro Leu Arg Pro Glu Gly Ala Arg Arg Arg Ser
 145                 150                 155                 160
 Gly Ala Pro Leu Leu Phe Pro Leu Lys Thr Leu Leu Gly Leu Leu Ala
                 165                 170                 175    
 Val Glu Glu Gln Leu Pro Ala Leu Leu Ser Ile Pro Arg His Asn Ser
             180                 185                 190        
 Gly Leu Leu Trp Pro Ser Pro Ala Leu Gln Glu Leu Ala Phe Asp His
         195                 200                 205            
 Pro Pro Val Met Phe Pro Glu Arg Gly Thr Ile Asn Val Asn Tyr Leu
     210                 215                 220                
 Gln Val Val Leu Ala Pro Gly Phe Arg His Cys Ala Tyr Thr Glu
 225                 230                 235                



      <210> 1660
      <211> 237
      <212> PRT
      <213> Homo sapiens


      <400> 1660
 Met Val Pro Ser Ser Thr Gly Ser Lys Val Ala Tyr Gly Lys Gln Ser
   1               5                  10                  15    
 Met Cys Leu Met Ala Leu Cys Met Trp Val Met Ser Phe Arg Ala Ser
              20                  25                  30        
 Pro Phe Val Leu Ala Ala Leu His Leu Lys Asn Gln Gly Gly Arg Gln
          35                  40                  45            
 Ile Cys Gly Lys Lys Gly Glu Lys Asp Thr Gly Asp Thr Glu Thr Ser
      50                  55                  60                
 Lys Ser Leu Arg Arg Pro Leu Phe Ile Ser Leu Thr Ala Val Asn Gln
  65                  70                  75                  80
 Ser Ala Ala Tyr Thr Pro Ser His Ser Ser Thr Asn Thr Thr Arg Ser
                  85                  90                  95    
 Lys Gly Thr Asp Ala Leu Thr Glu Thr Gln Val Ser Ser Gly Asn Trp
             100                 105                 110        
 Gly Met Asn Glu Ala Leu Ser His Leu Glu Val Gln Ala Leu Asp Phe
         115                 120                 125            
 Asp Ser Val Gly Leu Gly Phe Lys Leu Lys Ile Leu Pro Ala Thr Ala
     130                 135                 140                
 Gly Cys Thr Cys His Trp Gln Val Pro His Phe Asn Asn Asp Asp Asp
 145                 150                 155                 160
 Asn Ser Asn Ile Ser Ser Ser Pro Gln Pro Tyr Met Gln Pro Tyr Gln
                 165                 170                 175    
 Asn Pro Gly Ser Leu Gly Phe Gly Ala Arg Ser Ile Ala Phe Met Tyr
             180                 185                 190        
 His Asp Val Gln Asn Lys Arg Phe Lys Phe Pro Lys Ala Ala Ile Thr
         195                 200                 205            
 Arg Gly His Lys Lys Leu Ala Asn Pro Phe Lys Ser Lys Ser Val Lys
     210                 215                 220                
 Ile Leu Arg Val Gly Ile Leu Leu Leu Gly Lys Pro Val
 225                 230                 235        



      <210> 1661
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1661
 Met Ala Ala Val His Ser Leu Pro Thr Ala Gly Leu Phe Ser Thr Phe
   1               5                  10                  15    
 Gly Leu His Arg Asn Ala Ala Gly Ser Leu Gly Ala Gly Leu Gly Leu
              20                  25                  30        
 Ala Cys Arg Glu Met Leu Gln Arg Lys Ser Arg Gln Leu Gly Leu Val
          35                  40                  45            
 Ser Ala Asp Leu Leu Gln Trp Arg Arg Arg Arg Arg Arg His Arg His
      50                  55                  60                
 Leu Ala Val Ser Leu Gly Arg Arg Arg Leu Tyr Ser Ala Cys Arg Pro
  65                  70                  75                  80
 Thr Asp Tyr Pro Ser Arg Ile Tyr Ala Pro Arg Ile Leu Arg Ser Ser
                  85                  90                  95    
 Ala Leu Ser Leu Ser Ser Leu Ala Gly Ala Pro Thr Gly Gly Leu Ile
             100                 105                 110        
 Gly Tyr Ile Ala Ala
         115        



      <210> 1662
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1662
 Met Arg Arg Gln Thr Val Asn Lys Gln Gly Ile Gln Ala Leu Cys Leu
   1               5                  10                  15    
 Ala Leu Cys Ile Leu Ile His Thr Leu Leu Ser Arg Asp Ser Lys Ala
              20                  25                  30        
 Lys Glu Val Glu Asp Leu Glu Leu Phe Met Pro Glu Glu Ala Ala Gly
          35                  40                  45            
 Arg Gly Arg Thr Arg Trp Met Asn Glu Arg Thr Asn Glu Arg Thr Asn
      50                  55                  60                
 Glu Arg Thr Asn Glu Arg Thr Asn Thr Lys Gly His Ser Asn Gln Cys
  65                  70                  75                  80





      <210> 1663
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1663
 Met Val Pro Leu Pro Lys Gln Ser Leu Lys Phe Phe Cys Ala Leu Glu
   1               5                  10                  15    
 Val Val Leu Pro Ser Cys Asp Cys Arg Ser Pro Gly Ile Gly Leu Val
              20                  25                  30        
 Glu Glu Pro Met Asp Lys Val Glu Glu Ala Ser Ser Pro Lys Gly Ala
          35                  40                  45            
 Ile Pro Ser Val Pro Thr Pro Ser Asp Lys Trp Val Gln Asp Tyr Ile
      50                  55                  60                
 Lys Asp Met Lys Glu Asn
  65                  70



      <210> 1664
      <211> 113
      <212> PRT
      <213> Homo sapiens


      <400> 1664
 Met Ser Gln Val Met Phe His Ala Met Cys Val Pro Gln Cys Leu Thr
   1               5                  10                  15    
 Ile Tyr Leu Leu Lys Asn Ile Trp Ile Ser Ile Ser Ile Lys Leu Thr
              20                  25                  30        
 Cys Ile Ser Asn Arg Val Asp Lys Leu Leu Leu Lys Gly Pro Asp Ala
          35                  40                  45            
 Ser Gly Ala Arg Ala Pro Ala Ser Arg Ser Thr Thr Arg Leu Glu Arg
      50                  55                  60                
 Gly Ala Cys Thr Tyr Gln Thr Gly Arg Ser His Val Pro Ala Pro Leu
  65                  70                  75                  80
 Ser Gln Arg Asn Cys Leu Arg Trp Lys Pro Thr Arg Thr Thr Ala Pro
                  85                  90                  95    
 Gly Ser Arg Ala Arg Asn Glu Ser Pro Glu Tyr Gln Ala Ala Ala Lys
             100                 105                 110        
 Gln
    



      <210> 1665
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 1665
 Met Pro Phe Gln Val Trp Arg Ala Ala Cys Ala Ser Leu Ala Ala Ala
   1               5                  10                  15    
 Pro Ser Tyr Gly Ala Leu Glu His Asn Cys Val Val Leu Arg Tyr Leu
              20                  25                  30        
 Met Gly Phe Leu His Thr Gly Pro Pro Thr Val Thr Leu Ala Ser Ala
          35                  40                  45            
 Thr Arg Leu Ala Leu Ala Asn Gly Met
      50                  55        



      <210> 1666
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 1666
 Met Met His Leu Leu Gly Phe Cys Gly Gly Leu Ser Lys Leu Thr Ile
   1               5                  10                  15    
 Met Ala Glu Gly Glu Gly Gly Ala Ser Thr Ser His Gly Trp Lys Gln
              20                  25                  30        
 Glu Glu Glu Phe Lys Thr Gly Cys Ser Met Pro Leu Glu Ser Leu Arg
          35                  40                  45            
 Thr Gln Arg Ser Glu Phe Thr Leu Ala Met Phe Ile His Thr Lys Leu
      50                  55                  60                
 Gln Thr Leu Glu His Val Thr Glu Ala Leu Phe Arg Ala Lys Phe Lys
  65                  70                  75                  80
 Phe Ser Glu Cys Pro Lys Ser His Ile Ser Lys Lys Cys Asp Phe Thr
                  85                  90                  95    
 Lys Phe Asn Ala Tyr Thr Phe
             100            



      <210> 1667
      <211> 402
      <212> PRT
      <213> Homo sapiens


      <400> 1667
 Met Val Cys Ala Arg Ala Ala Leu Gly Pro Gly Ala Leu Trp Ala Ala
   1               5                  10                  15    
 Ala Trp Gly Val Leu Leu Leu Thr Ala Pro Ala Gly Ala Gln Arg Gly
              20                  25                  30        
 Arg Lys Lys Val Val His Val Leu Glu Gly Glu Ser Gly Ser Val Val
          35                  40                  45            
 Val Gln Thr Ala Pro Gly Gln Val Val Ser His Arg Gly Gly Thr Ile
      50                  55                  60                
 Val Leu Pro Cys Arg Tyr His Tyr Glu Ala Ala Ala His Gly His Asp
  65                  70                  75                  80
 Gly Val Arg Leu Lys Trp Thr Lys Val Val Asp Pro Leu Ala Phe Thr
                  85                  90                  95    
 Asp Val Phe Val Ala Leu Gly Pro Gln His Arg Ala Phe Gly Ser Tyr
             100                 105                 110        
 Arg Gly Arg Ala Glu Leu Gln Gly Asp Gly Pro Gly Asp Ala Ser Leu
         115                 120                 125            
 Val Leu Arg Asn Val Thr Leu Gln Asp Tyr Gly Arg Tyr Glu Cys Glu
     130                 135                 140                
 Val Thr Asn Glu Leu Glu Asp Asp Ala Gly Met Val Lys Leu Asp Leu
 145                 150                 155                 160
 Glu Gly Val Val Phe Pro Tyr His Pro Arg Gly Gly Arg Tyr Lys Leu
                 165                 170                 175    
 Thr Phe Ala Glu Ala Gln Arg Ala Cys Ala Glu Gln Asp Gly Ile Leu
             180                 185                 190        
 Ala Ser Ala Glu Gln Leu His Ala Ala Trp Arg Asp Gly Leu Asp Trp
         195                 200                 205            
 Cys Asn Ala Gly Trp Leu Arg Asp Gly Ser Val Gln Tyr Pro Val Asn
     210                 215                 220                
 Arg Pro Arg Glu Pro Cys Gly Gly Leu Gly Gly Thr Gly Ser Ala Gly
 225                 230                 235                 240
 Gly Gly Gly Asp Ala Asn Gly Gly Leu Arg Asn Tyr Gly Tyr Arg His
                 245                 250                 255    
 Asn Ala Glu Glu Arg Tyr Asp Ala Phe Cys Phe Thr Ser Asn Leu Pro
             260                 265                 270        
 Gly Arg Val Phe Phe Leu Lys Pro Leu Arg Pro Val Pro Phe Ser Gly
         275                 280                 285            
 Ala Ala Arg Ala Cys Ala Ala Arg Gly Ala Ala Val Ala Lys Val Gly
     290                 295                 300                
 Gln Leu Phe Ala Ala Trp Lys Leu Gln Leu Leu Asp Arg Cys Thr Ala
 305                 310                 315                 320
 Gly Trp Leu Ala Asp Gly Ser Ala Arg Tyr Pro Ile Val Asn Pro Arg
                 325                 330                 335    
 Ala Arg Cys Gly Gly Arg Arg Pro Gly Val Arg Ser Leu Gly Phe Pro
             340                 345                 350        
 Asp Ala Thr Arg Arg Leu Phe Gly Val Tyr Cys Tyr Arg Ala Pro Gly
         355                 360                 365            
 Ala Pro Asp Pro Ala Pro Gly Gly Trp Gly Trp Gly Trp Ala Gly Gly
     370                 375                 380                
 Gly Gly Trp Ala Gly Gly Ala Arg Asp Pro Ala Ala Trp Thr Pro Leu
 385                 390                 395                 400
 His Val
        



      <210> 1668
      <211> 256
      <212> PRT
      <213> Homo sapiens


      <400> 1668
 Met Arg Ser Gly Ala Ala Pro Ala Pro Ala Leu Gly Ala Ala Cys Leu
   1               5                  10                  15    
 Leu Leu Val Leu Ala Met Leu Gly Leu Ser Val Leu Glu Gly Ala Ser
              20                  25                  30        
 Trp Glu Ser Gln Gln Lys Ser Thr Leu Ser Ser Val Leu His Val Val
          35                  40                  45            
 Asp His Ser Phe Val Asn Leu Ser Ile Phe Pro Ser Ile His Leu Leu
      50                  55                  60                
 Ile Tyr Pro Leu Asn Tyr Pro Ser Thr Cys Ser Ser Ile His Pro Ser
  65                  70                  75                  80
 Ile His Pro Pro Ile His Pro Ser Thr His Gln Thr Ile His Pro Ser
                  85                  90                  95    
 Ile His Ser Pro Thr Lys Pro Ser Ile His Pro Ser Ile Gln Val Gln
             100                 105                 110        
 Asp His Pro Ser Ile His Pro Ser Ile His Pro Pro Asn His Pro Ser
         115                 120                 125            
 Ile His Pro Ser Ile His Pro Pro Thr Arg Pro Ser Ile His Pro Ser
     130                 135                 140                
 Ile His Pro Ser Ile His Pro Ser Ile His Pro Ser Ile His Gln Thr
 145                 150                 155                 160
 Ile His Pro Pro Thr Arg Thr Ile Tyr Pro Ser Ile Tyr Pro Ser Ile
                 165                 170                 175    
 His Pro Ser Ile His Pro Ser Ile His Pro Ser Thr Lys Pro Ser Ile
             180                 185                 190        
 His Pro Pro Asn Arg Pro Ser Ile His Pro Ser Ile His Pro Ser Ile
         195                 200                 205            
 His Pro Ser Ile His Pro Ser Ile His Pro Pro Asn His Pro Ser Ile
     210                 215                 220                
 His Pro Ser Ile His Pro Ser Ile His Pro Pro Thr His Pro Ser Ile
 225                 230                 235                 240
 Asn Pro Ser Ile His Pro Phe Ile Tyr Gln Ser Ile His Ser Ser Ile
                 245                 250                 255    





      <210> 1669
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1669
 Met Ala Gly Leu Asn Cys Gly Val Ser Ile Ala Leu Leu Gly Val Leu
   1               5                  10                  15    
 Leu Leu Gly Ala Ala Arg Leu Pro Arg Gly Ala Val Thr Leu Val Asn
              20                  25                  30        
 Val Ser Ser Thr Met Thr Ile Leu Val Asp Ile Val Ser Ser Ile Met
          35                  40                  45            
 Ala Phe Leu Ile Asp Ile Thr Pro Phe Lys Gly Tyr Phe Gly Glu Leu
      50                  55                  60                
 Ser Val Met Asp Ile Leu Ile Asp Ile Ile Pro Pro Gly Ser Cys Pro
  65                  70                  75                  80
 Gly Pro Ser Gly Ala Ala Arg Lys Glu Gln Gly Val Ser Gln Leu Val
                  85                  90                  95    
 Val Ile Leu Gln Thr Thr Val Lys Gln Arg Met Asp Cys Cys Gln Ser
             100                 105                 110        
 Ile Gly Ser Lys Gly Ser Asp Gly Gly Gly Glu Asp Ile Gly Asp Gly
         115                 120                 125            
 Gly Gly Ala Asp Ala Leu Pro Asp
     130                 135    



      <210> 1670
      <211> 335
      <212> PRT
      <213> Homo sapiens


      <400> 1670
 Met Ala Arg Ala Gly Leu Ser Trp Val Phe Leu Phe Pro Gln Val Leu
   1               5                  10                  15    
 Leu Leu Gln Ala Ile Val Thr Val Pro Glu Leu Gln Leu Ser Thr Ser
              20                  25                  30        
 Trp Val Asp Phe Arg Thr Cys Phe Val Ser Gln Gln Arg Val Trp Glu
          35                  40                  45            
 Val Tyr Leu Met His Leu Ser Ser Cys Arg Ser Tyr Trp Ala Thr Glu
      50                  55                  60                
 Thr Gly Glu Lys Met Thr Pro Gln Glu Gly Ser Ser Lys Leu Tyr Lys
  65                  70                  75                  80
 Ala Thr Leu Val Val Gln Glu Val Leu Gly Lys Lys Gly Val Gly Ser
                  85                  90                  95    
 Ser Thr Leu Leu Leu Trp Pro Ala Val Leu Gly Ala Gln Thr Arg Gln
             100                 105                 110        
 Ala Gly Val Asn Glu Gly Arg Ser Gln Val Ala Asp Phe Leu Arg Ile
         115                 120                 125            
 Pro Val Thr Gly Cys Pro Glu Gln Arg Arg Asn Pro Pro Ser Pro Pro
     130                 135                 140                
 Ala Pro Leu Gly Thr Gly Gly Pro Ala Glu Glu Arg Leu Gln Phe Pro
 145                 150                 155                 160
 Gly Val Ala Gly Ser Arg Arg Gly Arg Gly Arg Ile Leu Arg Ala Gly
                 165                 170                 175    
 Gly Ile Gly Arg Ala Ser Pro Gly Glu Gly Thr Gly Ala Pro Arg Pro
             180                 185                 190        
 Arg Ala Gly Gln Gly Arg Gly Gly Pro Gly Lys Pro Glu Ser Gly Gly
         195                 200                 205            
 Gly Gly Pro Val Ala Leu Arg Pro Gly Asp Cys Thr Cys Cys Val Leu
     210                 215                 220                
 Lys Ser Gln Pro Arg Gln Gln Arg Arg Gly Ala Cys Ser Ala Met Ala
 225                 230                 235                 240
 Phe Arg Val Arg Leu Arg Val Arg Gln Ser Val Arg Pro Pro Arg Gly
                 245                 250                 255    
 Val Ile Val Ala Ala Leu Gln Arg Pro Glu Thr Gln Gly Pro Ala Pro
             260                 265                 270        
 Ser Ser Ala Arg Pro Asp Cys Gly Pro Glu Ser Arg Gly Gly Leu Ala
         275                 280                 285            
 Leu Trp Arg Arg Leu Arg Gly Tyr Ala Ser Arg Asp Arg Val Leu Cys
     290                 295                 300                
 Asn Arg Arg Cys Pro His Ala Ala Arg Phe Pro Ser Lys Arg Thr Pro
 305                 310                 315                 320
 Ser Gly Ser Pro His Leu His Leu Met Ser Ser Trp Ala Val Pro
                 325                 330                 335



      <210> 1671
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 1671
 Met Val Ala Ala Thr Pro Lys Met Ala Ala Ser Leu Leu Phe Ser Asp
   1               5                  10                  15    
 Leu Gly Phe Leu Ala Ser Trp Ile Pro Lys Asn Gly Thr Leu Gly His
              20                  25                  30        
 Ala Val Ser Val Ile Ala Leu Leu Glu Ala Val Gly His Gly Arg Glu
          35                  40                  45            
 Pro Trp Asn Pro Ala Thr Ser Val Gln Leu Asp
      50                  55                



      <210> 1672
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1672
 Met Glu Thr Phe Tyr Phe Gly Ile Val Leu Arg Ala Ala Cys Ile Leu
   1               5                  10                  15    
 Val Asp Thr Ser Leu Ser Val Phe Ile Gln Met Asp Asn Gln Gly Tyr
              20                  25                  30        
 Cys Gly Ala Asp Ile Lys Ala Leu Cys Thr Glu Ala Ala Leu Ile Ala
          35                  40                  45            
 Leu Arg Arg Arg Tyr Pro Gln Ile Tyr Ala Ser Ser His Lys Leu Gln
      50                  55                  60                
 Leu Asp Val Ser Ser Ile Val Leu Ser Ala Gln Asp Phe Tyr His Ala
  65                  70                  75                  80
 Met Gln Asn Ile Val Pro Ala Ser Gln Arg Ala Val Met Ser Ser Gly
                  85                  90                  95    
 His Ala Leu Ser Pro Ile Ile Arg Pro Leu Leu Glu Arg Ser Phe Asn
             100                 105                 110        
 Asn Ile Leu Ala Val Leu Gln Lys Val Phe Pro His Ala Glu Ile Ser
         115                 120                 125            
 Gln Ser Asp Lys Lys Glu Gly Trp Asn Ala Val Ala
     130                 135                 140



      <210> 1673
      <211> 166
      <212> PRT
      <213> Homo sapiens


      <400> 1673
 Met Leu Leu Pro Leu Leu Ser Leu Leu Leu Asn Leu Lys Arg Val Val
   1               5                  10                  15    
 Ile Glu Ser Glu Gly Gly Gly Tyr Cys Tyr Ala Arg Lys Arg Cys Glu
              20                  25                  30        
 Tyr Thr Gly Asn Glu Ile Leu Lys Gly Val Ala Val Gln Met Leu Asp
          35                  40                  45            
 Gln Arg Asp Tyr Asp Ser Phe Asn Gln Val Ala Gly Leu Leu Lys Ala
      50                  55                  60                
 Tyr Pro Ser His Gly Ala Phe Glu Val Ala Pro Val Thr Ile Gln Asn
  65                  70                  75                  80
 Leu Val Ser Gly Arg Pro Thr Gln His Glu His Arg Leu Arg Ala Gly
                  85                  90                  95    
 Thr Leu Pro Pro Phe Pro Ala Asn Glu Gln Val Pro Gln Leu Leu Pro
             100                 105                 110        
 Arg Asp Leu Leu Thr Ser Gly Ala Ala Gly Asn Pro Phe Asp Ala Glu
         115                 120                 125            
 Asn Ser Gly Asp Ser His Ser Leu Gln Pro Ala Gly Pro Ser Val Thr
     130                 135                 140                
 Asp Arg Lys Arg Leu His Pro Leu Leu Arg His Leu Cys Arg Asn Glu
 145                 150                 155                 160
 Phe Thr Gly Ser Leu Met
                 165    



      <210> 1674
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 1674
 Met Pro Cys Ser Pro Arg Ser Gly Ser Pro Gly Phe Ala Ser Pro Phe
   1               5                  10                  15    
 Leu His Leu Ala Thr Ser Gln Val Gly Phe Gln Leu Leu Leu Leu Phe
              20                  25                  30        
 Leu Gly Cys Ile Leu Pro Tyr Pro Pro Pro Ala Ile Met Met Glu Leu
          35                  40                  45            
 Ala Val Cys Ser Gln Ile Leu Pro Glu Glu Asn Asn Glu His Glu Ser
      50                  55                  60                
 Pro Gln Glu Arg Val Glu Gly Gly Glu Thr Glu Lys Asp Pro Asp Arg
  65                  70                  75                  80
 Gln Lys Trp Lys Asp Lys Thr Ala Thr Ala Leu Lys Glu Val Ser Val
                  85                  90                  95    
 Pro Gln Lys Thr Gly Arg Ser Cys Asp Trp Leu Glu Arg Thr Asn Gln
             100                 105                 110        
 Met Trp Ile Asn Ile Glu Lys Asn Ser Trp Met Val Ser Trp Ile Leu
         115                 120                 125            
 Glu Glu Asp Gln Val
     130            



      <210> 1675
      <211> 178
      <212> PRT
      <213> Homo sapiens


      <400> 1675
 Met Leu Arg Arg Leu Gly Ala Gln Ala Ala Val Ala Leu Cys Val Gln
   1               5                  10                  15    
 Ala Ala Ala Ala Trp Gln Pro Pro Ser Pro Leu Ala Leu Pro Ala Ser
              20                  25                  30        
 Gln Asn Gln Gly Gln Val Ser Gln Trp Leu Arg Ser Ser Gln Ser Phe
          35                  40                  45            
 Cys Pro Ala Ala Ala Ala Ala Gln Glu Pro Glu Leu Arg Thr Arg Arg
      50                  55                  60                
 Ser Ala Pro His Gly Val Thr Ala Glu Cys Pro Cys Gln Arg Pro Arg
  65                  70                  75                  80
 Ser Pro Ser Gly Gly Gly Val Gly Glu Arg His Gly Leu Gly Ala Leu
                  85                  90                  95    
 Arg Leu Gly Ala Leu Ala Ile Pro Arg Pro Thr Arg Pro Cys Thr Ser
             100                 105                 110        
 Ser Pro Pro Gly His Leu Ser Cys Ser Arg Leu Leu Cys Ala Gly Ser
         115                 120                 125            
 Ser Leu Gln Ala Thr Pro Glu Pro Ala Arg Thr Pro His Ile Ser Glu
     130                 135                 140                
 Pro Gly Pro Asp Val Pro Val Ala Ala Ala Lys Pro Gly Gly Leu Pro
 145                 150                 155                 160
 Cys Ser Ser Cys Thr Gly Ala Gly Thr Gly Pro Gln Pro His Pro Arg
                 165                 170                 175    
 Trp Leu
        



      <210> 1676
      <211> 170
      <212> PRT
      <213> Homo sapiens


      <400> 1676
 Met Lys Pro Phe Trp Leu Val Leu Pro Val Arg Ser Val Ser Phe Gln
   1               5                  10                  15    
 Gln Cys Gln Leu Gln Glu Gln Leu Asn Pro Ala Ser Asn Phe Ser Ser
              20                  25                  30        
 Ala Gly Arg Ala Ser Phe Ile Leu Leu Pro Trp Thr Pro Ala Leu Ala
          35                  40                  45            
 Ala Arg Ala Leu Ser Ser Glu Leu Ser Val Gln Ala His Arg Pro Leu
      50                  55                  60                
 Leu Ser Gly Gly His Ile Thr Glu Thr Val Ile Leu Asn Arg Ser Leu
  65                  70                  75                  80
 Glu Arg Glu Ile Gln Ala Ser Pro Ser His Leu His Ser Arg Lys Glu
                  85                  90                  95    
 Gln Arg Glu Ile Glu Lys Ile Lys Gln Arg Ala Phe Ile Pro Glu Ile
             100                 105                 110        
 Thr Gln Leu Cys Ala Lys Ser Ser Leu Leu Asn Ala Lys Ala Leu His
         115                 120                 125            
 His Gln Asn Asn Cys Phe Asn Gln Glu Gly Glu Glu Pro Met Pro Gln
     130                 135                 140                
 Gln Ser Pro Glu Ser His Thr Asp Thr Ser Cys Ile Ser Lys Ser Leu
 145                 150                 155                 160
 Leu Leu Ser Pro Pro His Val Ser Leu Pro
                 165                 170



      <210> 1677
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1677
 Met Pro Asp Leu Phe Phe His Val Ser Phe Ile Leu Ile Leu Lys Thr
   1               5                  10                  15    
 Val Ser Phe Met Ile Tyr Leu Asn Glu Glu Arg Thr Ala Glu Trp Met
              20                  25                  30        
 Ile Leu Ile Phe Pro Cys Phe Ser Leu Glu Cys Met Ile Gly Trp Cys
          35                  40                  45            
 Asn Ser Ala Ser Ser Asp Leu
      50                  55



      <210> 1678
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 1678
 Met Ala Asn Trp Lys Gly Phe Pro Phe Trp His Gln Leu Ile Phe Ala
   1               5                  10                  15    
 Gly Ile Ala Ala Leu Lys Ile Glu Ile Lys Arg Val Lys Lys Ser Glu
              20                  25                  30        
 Gln Phe Met Ala Gln Lys Gln Leu Pro Val Phe Leu Asp Phe Thr Gly
          35                  40                  45            
 His Leu
      50



      <210> 1679
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 1679
 Met Ala Gln Ile Leu Tyr Gln Ile Ala Leu Val Asn Gln Cys Phe Leu
   1               5                  10                  15    
 Thr Leu Ile Gly Lys Glu Ser Ala Ser Glu Leu Pro Gly Ser Phe Val
              20                  25                  30        
 Lys Lys Ala Asp Ser Trp Ala Gln Pro His Leu Leu Asn Glu Asn Val
          35                  40                  45            
 Trp Arg Asn Gln Lys Leu Tyr Leu Ala Lys Asp Glu Leu Thr Pro Asn
      50                  55                  60                
 Ser Lys Arg Phe Glu Leu Ala Pro Lys His Lys Pro His Lys Tyr Pro
  65                  70                  75                  80
 Asn Lys Ala Ile Asn Leu Gly Leu Leu Ser Phe Ala Cys Asn His Lys
                  85                  90                  95    
 Leu Glu Pro Lys Phe Val Pro Ser Ser Val Ile Asn Met His Lys Leu
             100                 105                 110        
 Leu Gly Val
         115



      <210> 1680
      <211> 162
      <212> PRT
      <213> Homo sapiens


      <400> 1680
 Met Gly Thr Lys Leu Gln Ser Trp Thr Phe Trp Leu Cys Leu Leu Cys
   1               5                  10                  15    
 Asn Gly Ile Arg Ser Thr Gly Leu Gly Arg Gln Leu Asp Asn Gly Asp
              20                  25                  30        
 Arg Met Ser Gly Gln Ser Trp Phe His Ser Met Leu Val Asn Glu Leu
          35                  40                  45            
 Ser Pro Gly Ser Leu Gln Ser Ser Gly Pro Gln Leu Thr Val Glu Leu
      50                  55                  60                
 Glu Val Pro Gln His Pro Pro Leu Pro Pro Ser Arg Ala Pro Leu Leu
  65                  70                  75                  80
 Leu Leu Asn Gly Glu Arg Met Glu Pro Thr Leu Glu Thr Arg Asp Leu
                  85                  90                  95    
 Ala Lys Trp Val Gly Gln Glu Val Pro Gly Lys Arg Gln Thr Glu Leu
             100                 105                 110        
 Gln Asn Ala Trp Leu Leu Leu Leu Asn Gly Trp Gly Glu Arg Asp Thr
         115                 120                 125            
 Ala Cys Asp Gly Thr Asp Lys Pro Val Gln Ile Ala Leu Asp Ser Leu
     130                 135                 140                
 Thr Asp Thr Val Ser Leu Lys His Ile Ala His Leu Phe Leu Phe Val
 145                 150                 155                 160
 Ile Leu
        



      <210> 1681
      <211> 180
      <212> PRT
      <213> Homo sapiens


      <400> 1681
 Met Pro Tyr Pro Pro Ser Thr Ile Met Val Phe His Thr Ala Leu Pro
   1               5                  10                  15    
 Leu Thr Thr Ala Leu Thr Leu Arg Leu Lys Lys Cys Gly Thr Val Leu
              20                  25                  30        
 Ile Leu Met Glu Phe Thr Gly Leu Thr Met Phe Pro Ile Ile Leu Lys
          35                  40                  45            
 Gln Val Glu Cys Pro Phe Glu Val Thr Leu Thr Thr Pro Thr Ile Ala
      50                  55                  60                
 Leu Glu Thr Asn Lys Cys Thr Gln Thr Thr Ala Thr Tyr Leu Leu Leu
  65                  70                  75                  80
 Ala Glu Arg Ile Leu Arg Glu Lys Gln Asp Lys Glu Ile Gln Ile Ser
                  85                  90                  95    
 Ser Ala Ser Pro Arg Asn Ser Lys Ala Gln Leu Arg Asn His Arg Glu
             100                 105                 110        
 Leu Arg Leu Thr Ala Leu Lys Glu Lys Glu Lys Val Gln Phe Gln Met
         115                 120                 125            
 Val Tyr Asn Lys Ala Val Gln Leu Ala Leu Asn Lys Gly Ile Thr Ser
     130                 135                 140                
 Ile Cys Lys Ala Glu Asp Ser Pro Ser Ala Glu Pro Glu Asn Gly Leu
 145                 150                 155                 160
 Tyr His Ser Gly Ser Glu Gly Arg Gly Arg Arg Arg Lys Gly Gly Leu
                 165                 170                 175    
 Arg Lys Glu His
             180



      <210> 1682
      <211> 416
      <212> PRT
      <213> Homo sapiens


      <400> 1682
 Met Gly Lys Val His Tyr Leu Val Lys Ser Val Pro Phe Leu Phe Leu
   1               5                  10                  15    
 Val Val Met Asp Val Leu Val Met Val Asp Cys Cys Asp Gly Phe Val
              20                  25                  30        
 Gly Ser Ile Pro Leu Asp Pro Lys Ala Gln Gln Gly Leu Gln Lys Ile
          35                  40                  45            
 Val Lys Asp Leu Lys Ala Gln Gly Leu Val Lys Pro Cys Asn Ser Pro
      50                  55                  60                
 Cys Asn Thr Pro Ile Leu Gly Val Gln Lys Pro Asn Gly Gln Trp Arg
  65                  70                  75                  80
 Leu Val Gln Asp Leu Arg Ile Ile Asn Glu Ala Leu Val Pro Leu Tyr
                  85                  90                  95    
 Pro Ala Val Pro Asn Pro Tyr Thr Leu Leu Ser Gln Ile Pro Glu Glu
             100                 105                 110        
 Ala Glu Trp Phe Thr Val Leu Gly Leu Lys Asp Asp Phe Phe Cys Ile
         115                 120                 125            
 Pro Val His Pro Asp Ser Gln Phe Leu Phe Ala Phe Glu Glu Pro Ser
     130                 135                 140                
 Asn Pro Thr Ser Gln Leu Thr Trp Thr Val Leu Pro Lys Gly Phe Arg
 145                 150                 155                 160
 Asp Ser Pro His Leu Phe Gly Gln Val Leu Ala Gln Asn Leu Ser Gln
                 165                 170                 175    
 Phe Ser Tyr Leu Asp Thr Leu Val Leu Arg Tyr Val Asp Asp Leu Leu
             180                 185                 190        
 Leu Ala Ala Arg Ser Glu Thr Leu Cys His Gln Ala Thr Gln Ala Leu
         195                 200                 205            
 Leu Asn Phe Leu Thr Thr Cys Gly Tyr Lys Val Ser Lys Pro Lys Ala
     210                 215                 220                
 Gln Leu Cys Ser Gln Glu Val Thr Tyr Leu Gly Leu Lys Leu Ser Lys
 225                 230                 235                 240
 Gly Thr Arg Ala Leu Ile Arg Trp Thr Pro Glu Ala Glu Ala Ala Phe
                 245                 250                 255    
 Gln Ala Leu Lys Arg Ala Leu Thr Gln Ala Pro Val Leu Ser Leu Pro
             260                 265                 270        
 Thr Gly Gln Asp Phe Ser Leu Tyr Val Thr Glu Lys Thr Gly Ile Ala
         275                 280                 285            
 Leu Gly Val Leu Thr Gln Val Gln Gly Met Ser Leu Gln Pro Met Ala
     290                 295                 300                
 Tyr Leu Ser Lys Glu Ile Asp Val Ala Ala Lys Gly Trp Pro His Cys
 305                 310                 315                 320
 Leu Gln Val Val Val Ala Val Ala Val Leu Val Ser Glu Ala Val Lys
                 325                 330                 335    
 Ile Ile Gln Gly Arg Asp Leu Thr Val Trp Thr Ser His Asp Val Lys
             340                 345                 350        
 Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp Leu Ser Asp Asn Cys Leu
         355                 360                 365            
 Leu Lys Tyr Gln Ala Leu Leu Leu Glu Arg Pro Val Leu Gln Leu His
     370                 375                 380                
 Thr Cys Ala Thr Leu Asn Pro Ala Thr Phe Leu Pro Asp Asn Glu Glu
 385                 390                 395                 400
 Lys Val Glu Tyr Asn Cys Gln Gln Val Ile Ala Gln Thr Tyr Ala Thr
                 405                 410                 415    





      <210> 1683
      <211> 197
      <212> PRT
      <213> Homo sapiens


      <400> 1683
 Met Asn Gly Asn Met His Leu Arg Phe Trp Phe Cys Gln Ala Ala Leu
   1               5                  10                  15    
 Leu Tyr Tyr Arg His Phe Gln Leu Glu Glu His Thr Leu Ser Tyr Met
              20                  25                  30        
 Glu Lys Pro Gln Ala Leu Ile Asp Leu Met Gln Ser Ile Phe Leu Thr
          35                  40                  45            
 His Asn Pro Thr Trp Ala Asp Cys Lys Gln Leu Leu Leu Ser Leu Phe
      50                  55                  60                
 Asn Thr Glu Glu His Arg Arg Val Ile Gln Ala Ala His Gln Arg Leu
  65                  70                  75                  80
 Glu Lys Asn Ala Pro Val Gly Thr Gly Asp Val Arg Gln Cys Ala Arg
                  85                  90                  95    
 Gln Ala Leu Pro Ile Glu Thr Asp Pro Gly Trp Asp Pro Asn Gln Ala
             100                 105                 110        
 Gln Asp Leu Leu Lys Leu Leu Arg Tyr Gln Glu Ala Leu Ile Gln Gly
         115                 120                 125            
 Ile Lys Thr Glu Gly Lys Lys Ala Thr Asn Thr Gly Lys Val Ser Glu
     130                 135                 140                
 Val Tyr Gln Lys Pro Asp Glu Ser Pro Ser Glu Phe Tyr Gly Arg Leu
 145                 150                 155                 160
 Arg Gln Ala Tyr Arg His Tyr Thr Pro Phe Asp Pro Glu Ala Ala Gly
                 165                 170                 175    
 Asn Arg Cys Met Val Asn Ala Ala Phe Val Ser Gln Ala Gln Asn Asp
             180                 185                 190        
 Ile Lys Arg Lys Leu
         195        



      <210> 1684
      <211> 327
      <212> PRT
      <213> Homo sapiens


      <400> 1684
 Met Gly Trp Arg Gly Leu Ile Ala Ala Leu Pro Leu Leu Ser Leu Val
   1               5                  10                  15    
 Gln Pro Ala Leu Gly Thr Ser Ser Lys Asp Glu Asp Val Gly Arg Ser
              20                  25                  30        
 Trp Ser Ala Asp Cys His Thr Cys Asp Gln Leu Ala Gln Asp Met Ala
          35                  40                  45            
 Glu Glu Ala Ala Gln Asn Ile Ser Asp Asp Gln Glu Arg Cys Leu Gln
      50                  55                  60                
 Ala Ala Cys Cys Leu Ser Phe Gly Gly Glu Leu Ser Val Ser Thr Asp
  65                  70                  75                  80
 Lys Ser Trp Gly Leu His Leu Cys Ser Cys Ser Pro Pro Gly Gly Gly
                  85                  90                  95    
 Leu Trp Val Glu Val Tyr Ala Asn His Val Leu Leu Met Ser Asp Gly
             100                 105                 110        
 Lys Cys Gly Cys Pro Trp Cys Ala Leu Asn Gly Lys Ala Glu Asp Arg
         115                 120                 125            
 Glu Ser Gln Ser Pro Ser Ser Ser Ala Ser Arg Gln Lys Asn Ile Trp
     130                 135                 140                
 Lys Thr Thr Ser Glu Ala Ala Leu Ser Val Val Asn Glu Lys Thr Gln
 145                 150                 155                 160
 Ala Val Val Asn Glu Lys Thr Gln Ala Pro Leu Asp Cys Asp Asn Ser
                 165                 170                 175    
 Ala Asp Ser Leu Arg Val Phe Ala Asp Ser Ser Ile Gly Glu Asn Trp
             180                 185                 190        
 Thr Leu Gln Met Val Cys Asp Pro Asp Thr Trp Met Arg Gly Pro Ser
         195                 200                 205            
 Ser His Gly Leu Pro Pro Gly Ile Pro Arg Thr Pro Ser Phe Thr Ala
     210                 215                 220                
 Ser Gln Ser Gly Ser Glu Ile Leu Tyr Pro Pro Thr Gln His Pro Pro
 225                 230                 235                 240
 Val Ala Ile Leu Ala Arg Asn Ser Asp Asn Phe Met Asn Pro Val Leu
                 245                 250                 255    
 Asn Cys Ser Leu Glu Val Glu Ala Arg Ala Pro Pro Asn Leu Gly Phe
             260                 265                 270        
 Arg Val His Met Ala Ser Gly Glu Ala Leu Cys Leu Met Met Asp Phe
         275                 280                 285            
 Gly Asp Ser Ser Gly Val Glu Met Arg Leu His Asn Met Ser Glu Ala
     290                 295                 300                
 Met Ala Val Thr Ala Tyr His Gln Tyr Ser Lys Gly Asp Leu Leu Ala
 305                 310                 315                 320
 Ser Leu Val Thr His Leu Leu
                 325        



      <210> 1685
      <211> 40
      <212> PRT
      <213> Homo sapiens


      <400> 1685
 Met Ala Ile Thr Leu Cys Ser Ile Pro Thr Leu Ala Ala Asp Ser Cys
   1               5                  10                  15    
 Gln Ala Val Ser Asn Pro Val Asp Glu Ala Thr Trp Gln Ala Ser Asp
              20                  25                  30        
 Cys Cys Leu Pro Ser Asn Ser Gln
          35                  40



      <210> 1686
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 1686
 Met Trp Leu Leu Ile Ile Cys Cys Lys Ser Ala Ser Ala Leu Val Ile
   1               5                  10                  15    
 Cys Trp Ile Lys Lys Phe His Pro Val Phe Glu Glu Ser Leu Leu Tyr
              20                  25                  30        
 Leu Leu Gln Glu Gly Ser Leu Cys Tyr Leu Gln Arg Lys Lys Thr Asp
          35                  40                  45            
 Phe Ile Phe Leu Val His Leu Leu Val Gly Gln Gly Gly Met Glu Phe
      50                  55                  60                
 Glu Leu Val Phe Arg Phe Thr Asp Pro Thr Tyr Val Phe Phe Ser Arg
  65                  70                  75                  80
 Gly Phe Ser Val Ile Leu Lys Gln Thr Glu Ser Tyr Ile Ile Tyr Gln
                  85                  90                  95    
 Tyr Phe Arg Lys Arg Glu Thr Lys Val Met Ala Val Leu Ala Lys Leu
             100                 105                 110        
 Ile Leu Lys Leu Asn Lys Ser
         115                



      <210> 1687
      <211> 91
      <212> PRT
      <213> Homo sapiens


      <400> 1687
 Met Met Ser Thr Leu Thr Val Leu Lys His Met Leu Thr Pro Ala Leu
   1               5                  10                  15    
 Ala Ser Arg Leu Gln Arg Leu Ala Lys Asp Leu Leu Lys Gln Val Gln
              20                  25                  30        
 Val Gln Asp Ser Gly Ser Trp Ala Asn Asn Lys Val Ser Ala Leu Asp
          35                  40                  45            
 Arg Thr Leu Gly Glu Ile Thr Arg Ile Leu Glu Lys Glu Ile Val Leu
      50                  55                  60                
 Asn Tyr Ile Leu Ala Ser Asp Ser Thr Val Val Trp Arg Asn Arg Lys
  65                  70                  75                  80
 Gln Pro Ile Gln Cys Gly Ile Val Ala Glu Leu
                  85                  90    



      <210> 1688
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 1688
 Met Leu Asn Phe Ala Gly Pro Val Thr Gln Gln Phe Val Ser Phe Phe
   1               5                  10                  15    
 Val Leu Leu Ala Val Asn Thr Phe Met Pro Arg Arg Val Ala Leu Lys
              20                  25                  30        
 Thr Pro Asp Glu Leu Ala Asp Val Phe Pro Ile Ser Cys Asn Gln Ile
          35                  40                  45            
 Gln Tyr Leu Ser Tyr Gly Thr Ser Ile Gly Asp Val Asp Val
      50                  55                  60        



      <210> 1689
      <211> 431
      <212> PRT
      <213> Homo sapiens


      <400> 1689
 Met Gly Phe Thr Val Leu Leu Ala Ser Thr Phe Leu Cys Leu Phe Leu
   1               5                  10                  15    
 Ala Pro Leu Val Cys Arg Phe Leu Val Ser Ile Pro Lys Phe Ser Ser
              20                  25                  30        
 Phe Cys Ser Phe Thr Phe Lys Ser Thr Pro Arg Gln Asp Gln Asp Leu
          35                  40                  45            
 Leu Ala Phe Leu Glu Met Trp Ala Leu Cys Arg Asp Asp Arg Ser Gln
      50                  55                  60                
 Cys Leu Glu Pro Ser Pro Asn Thr Ala Glu Leu Glu Pro Ala Gln Ser
  65                  70                  75                  80
 Ser Gln Val Ile Lys Glu Asn Pro Leu Gly Pro Gln Arg Tyr Asp His
                  85                  90                  95    
 Trp Thr Tyr Arg Val Ala Ser Ala Gly Thr Lys Ile Cys His Ser Leu
             100                 105                 110        
 Leu Lys Pro Pro Pro Met Gly Ser Pro Pro Phe Thr Val Gly Ser His
         115                 120                 125            
 Arg Asn Cys His Ala Ser Glu Pro Asp Pro Ala Gln Ala Leu Arg Ser
     130                 135                 140                
 Val Thr Cys His Leu Gly Asp Gly Val Pro Val Ile Leu Phe Thr Leu
 145                 150                 155                 160
 Phe Pro Ala Asp Ser Pro Ser Leu Arg Ala His Val Pro Gly His Gly
                 165                 170                 175    
 Pro Ser Ala Ala Leu Glu Ala Ala Gly Thr Ser Arg Cys Ser Ala Ser
             180                 185                 190        
 Lys Arg Ala Arg Gly Asp Arg Thr Asp Lys Glu Gly Leu His Ala Lys
         195                 200                 205            
 Val Pro Leu Pro Ser Gln Ala Pro Arg Val Pro Leu Arg Ser Pro Ser
     210                 215                 220                
 Leu Tyr Leu Ile Ser Met Asn Gly Ile Val Ile His Ala Ala Leu Asp
 225                 230                 235                 240
 Ser Ala Leu Val His Lys Glu Ser Thr Gln Glu Arg Met Ala Ala Val
                 245                 250                 255    
 Ser Pro Thr Thr Arg Cys Gln Glu Ser Val Thr Phe Glu Asp Val Ala
             260                 265                 270        
 Val Val Phe Thr Asp Glu Glu Trp Ser Arg Leu Val Pro Ile Gln Arg
         275                 280                 285            
 Asp Leu Tyr Lys Glu Val Met Leu Glu Asn Tyr Asn Ser Ile Val Ser
     290                 295                 300                
 Leu Ala Pro Pro Pro Pro Ser Lys Asn Gln Leu Ser Leu Ile His Met
 305                 310                 315                 320
 Phe Pro Thr Trp Met Arg Thr Gly Leu Glu Ala Leu Gln Ala Tyr Val
                 325                 330                 335    
 Glu Ile Pro Leu Gln Pro Lys Val Ser Lys Gly Thr Pro Val Leu Arg
             340                 345                 350        
 Gly Ala Val Leu Arg Ser His Cys Gly Thr Leu Gln Gln Val Ile Leu
         355                 360                 365            
 Pro Leu Gly Pro Ser Phe Leu Ser Ala Asn Gly Asn Ser Gln Gln Ser
     370                 375                 380                
 Pro His Thr Gly Gly Trp Cys Glu Leu Ala Lys Thr Thr Asp Val Ser
 385                 390                 395                 400
 Met Lys Leu Leu Ala Leu Ser Pro Ala Leu Pro Ile Pro Gly Asn Lys
                 405                 410                 415    
 Leu Ser Phe Met Gln Glu Ala Asp Ser Ser Val Glu Thr Asp Ala
             420                 425                 430    



      <210> 1690
      <211> 86
      <212> PRT
      <213> Homo sapiens


      <400> 1690
 Met Phe Arg Leu Ile Leu Leu Pro Val Leu Lys Leu Gln Gly Asp Ile
   1               5                  10                  15    
 Asp Gln Gln Glu Met Ile Pro Ser Lys Lys Asn Ala Val Leu Val Asp
              20                  25                  30        
 Gly Val Val Leu Asn Gly Pro Thr Thr Asp Ala Lys Ala Gly Glu Lys
          35                  40                  45            
 Phe Val Glu Glu Ala Cys Arg Leu Ile Met Glu Glu Val Val Leu Lys
      50                  55                  60                
 Ala Thr Asp Val Asn Glu Lys Pro Leu Lys Pro Leu Ile Phe Phe Pro
  65                  70                  75                  80
 Tyr Asp Thr Cys Leu Phe
                  85    



      <210> 1691
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1691
 Met Ala Val Ala Leu Ser Ile Ile Leu Pro Leu Gly Ala Gly Cys Lys
   1               5                  10                  15    
 Ala Ala Glu Gly Arg Ser Tyr Ser Thr Leu Gly Pro Ser Asn Glu Pro
              20                  25                  30        
 His Tyr Ser Glu Gly Ser Ile Ser Met Gln Ser Glu Ser Pro Ala Gly
          35                  40                  45            
 Thr Trp Leu Cys Arg Ala Pro Gly Asp Leu Phe Ala Phe Thr Ser Lys
      50                  55                  60                
 Val Pro Lys Thr Glu Ala Lys Met Gln Glu Ala Thr Gly Pro Phe Ala
  65                  70                  75                  80
 Gln Leu Gln Val Tyr Asn Leu Pro Val Leu Leu Asn Ser Trp Asn Ser
                  85                  90                  95    
 Asp Met Gly His Phe Gln Thr Ser Pro Asp Ile Thr Glu Pro Gln Tyr
             100                 105                 110        
 Leu Leu Asp Val Ile
         115        



      <210> 1692
      <211> 154
      <212> PRT
      <213> Homo sapiens


      <400> 1692
 Met Arg Ile Pro Pro Ser Arg Pro Ala Arg Gly Leu Trp Thr Arg Trp
   1               5                  10                  15    
 Val Pro Val Thr Val Leu Pro Gly Cys Val Gly Cys Arg Thr Val Ala
              20                  25                  30        
 Ala Leu Ala Ser Trp Thr Val Arg Asp Val Lys Glu Arg Ile Phe Ala
          35                  40                  45            
 Glu Thr Gly Phe Pro Val Ser Glu Gln Arg Leu Trp Arg Gly Gly Arg
      50                  55                  60                
 Glu Leu Ser Asp Trp Ile Lys Ile Gly Asp Leu Thr Ser Lys Asn Cys
  65                  70                  75                  80
 His Leu Phe Val Asn Leu Gln Ser Lys Gly Leu Lys Gly Gly Gly Arg
                  85                  90                  95    
 Phe Gly Gln Thr Thr Pro Pro Leu Val Asp Phe Leu Lys Asp Ile Leu
             100                 105                 110        
 Arg Arg Tyr Pro Glu Gly Gly Gln Ile Leu Lys Ile Ile Val Gln Gly
         115                 120                 125            
 Phe Thr Arg Gln Pro Thr Asn Gln Pro Thr Asn Gln Pro Ala Ser Gln
     130                 135                 140                
 Pro Thr Gly Gln Pro Asn Thr Phe Tyr Asp
 145                 150                



      <210> 1693
      <211> 290
      <212> PRT
      <213> Homo sapiens


      <400> 1693
 Met Val Met Leu Gln Ile Pro Val Ala Ser Thr Arg Gly Leu Leu Ala
   1               5                  10                  15    
 Pro Ile Trp Ala Thr Cys Thr Thr Arg Arg Val Gly Leu His Thr Ala
              20                  25                  30        
 Ala Gly Pro Gly Gly Asn Arg Ala Leu Ile Ala Pro Gly Ile Val Phe
          35                  40                  45            
 His Arg Ile Ser Gln Thr Pro Asn Leu Gln Val Leu Glu Thr Leu Lys
      50                  55                  60                
 Glu Ser Pro Phe Pro Leu Val Glu Thr Arg Gly Arg Asn Lys Gln Val
  65                  70                  75                  80
 Glu Ser Gln Gly Tyr Ser Phe Gln Pro Met Gly Leu Gly Leu Gln His
                  85                  90                  95    
 Thr Lys Leu Thr Ser Arg Lys Ala Ile Phe Leu Asp Arg Phe Arg Pro
             100                 105                 110        
 Gly Ile Gly Trp Thr Asp His Met Ile Gln His Pro Asn Trp Arg Ser
         115                 120                 125            
 Leu Asn Asn Arg Lys Arg Glu Lys Ile Phe Ser Asn Gly Gln Leu Asn
     130                 135                 140                
 Ser Leu Lys Pro Gln Phe Lys Pro Ile Leu Ser Ala Trp Phe Phe Asn
 145                 150                 155                 160
 Asp Asn Asn Ser Ser Gln Gly His Gly Gln Lys Arg Ser Pro Cys Ser
                 165                 170                 175    
 Glu Glu Ala Gln Leu Phe Gln Arg Leu Lys Pro Trp Ile Phe Phe Ser
             180                 185                 190        
 Gly Pro Val Ser Ser Arg Ala Ser Cys Ser Ala Thr Val Arg Lys Phe
         195                 200                 205            
 His Val Tyr Val Phe Gly Leu His Ala Gly Asp Phe Arg Pro Thr Ala
     210                 215                 220                
 Val Ala Met Ala Ala Phe Pro Glu Gly Lys Glu Pro Lys Gly Ile Thr
 225                 230                 235                 240
 Asp Thr Leu Pro Asp Arg Gly Ala Phe Met Ala Ala Thr Ile Thr Ala
                 245                 250                 255    
 Thr Ser Ser Glu Pro Ser Pro Arg Ile Arg Gly Val Ala Val Asp Ser
             260                 265                 270        
 Lys Met Lys Cys His Leu Cys Gly Ala Thr Val Gly Asp Leu Val Pro
         275                 280                 285            
 Asn Thr
     290



      <210> 1694
      <211> 44
      <212> PRT
      <213> Homo sapiens


      <400> 1694
 Met Thr Leu Leu Leu Leu Pro Leu Leu Leu Ala Ser Leu Leu Ala Ser
   1               5                  10                  15    
 Cys Ser Cys Asn Lys Gly Gln Val Val Ser Met Gly Thr Val Tyr Pro
              20                  25                  30        
 Ala Ile Gly Glu Gly Tyr Asp Leu Pro Gln Thr Leu
          35                  40                



      <210> 1695
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 1695
 Met Arg Leu Trp Leu Leu Leu Ser Arg Val Pro Pro Gly Ser Leu His
   1               5                  10                  15    
 Ala Leu Pro Val Arg Gly Arg Asp Ala Asn Pro Ser Val Pro Thr Ala
              20                  25                  30        
 Asp Pro Glu Pro Gly Lys Thr Ala Pro Gly Ala Ser Arg Glu Leu Ser
          35                  40                  45            
 Ser Ser Gly Arg Gly Gly Arg Ser Ser Cys Gly Gly His Thr Leu Asp
      50                  55                  60                
 Glu Val Arg Ala Trp Pro Ala Pro Ala Ser Gly Ala Arg Glu Ala Glu
  65                  70                  75                  80
 Glu Arg Asp Gly Gly Gly Asn Ala Arg Ala Gly Ala Leu Pro Asp Gly
                  85                  90                  95    
 Trp Met Glu Ala Met Gln Asp Lys Phe Leu Leu Lys Ser Ile Leu Cys
             100                 105                 110        
 Phe Gly Leu Glu Asp Arg Thr Tyr
         115                 120



      <210> 1696
      <211> 180
      <212> PRT
      <213> Homo sapiens


      <400> 1696
 Met Leu Thr Gln Asn Ser Arg Val Asn Leu Gln Glu Glu Ala Ile Val
   1               5                  10                  15    
 Gly Gly Ser Leu Ile Ala Pro Phe Phe Leu Val Leu Val Phe Glu Leu
              20                  25                  30        
 Leu Tyr Val Phe Glu Leu Leu Tyr Ala Gly Val Val Arg Ala Cys Glu
          35                  40                  45            
 Glu Leu Met Leu Ser Leu Glu Thr Gln Gly Lys Trp Ala Thr Glu Gln
      50                  55                  60                
 Met Glu Lys Ile Cys Leu His Cys Lys Cys Pro Gln Glu Glu His Met
  65                  70                  75                  80
 Val Thr Val Met Pro Leu Glu Met Glu Lys Thr Ile Ser Lys Leu Met
                  85                  90                  95    
 Phe Asp Phe Gln Arg Asn Ser Thr Ser Asp Asp Asp Ser Gly Cys Ala
             100                 105                 110        
 Leu Glu Glu Tyr Ala Trp Val Pro Pro Gly Leu Lys Pro Glu Gln Ala
         115                 120                 125            
 Phe Cys Cys Gly Ile Val Ile Lys Ile Gln Val Arg Pro Ser Gly Val
     130                 135                 140                
 Leu Trp Leu Cys Gly Ala Cys Gly Ser Tyr Ser Gly Pro Gln Met Glu
 145                 150                 155                 160
 Pro Leu Asp Ser Glu Ser Ser Asn Ala Pro Ser Arg Leu Trp Asp Tyr
                 165                 170                 175    
 Leu Leu Lys Tyr
             180



      <210> 1697
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 1697
 Met Gln Leu Leu Gly Phe Ser Lys Lys Val Met Ile Ile Lys Leu Leu
   1               5                  10                  15    
 Leu Arg Lys Ala Asp Leu Glu Trp Asn Met Gly Trp Thr Gly Gln Gly
              20                  25                  30        
 Met Glu Gly Gly Gly Glu Ala Arg Gly Lys Trp Trp Ser Ile Ala Val
          35                  40                  45            
 Asn Asn Thr Gly Ser Gly Ala Ile Met Ala Arg Ala Lys Pro Gly Ser
      50                  55                  60                
 Ala Ile Phe Gly Leu Thr Glu Gly Arg Met Leu Gln Leu Asn Pro Ala
  65                  70                  75                  80
 Lys Ser Trp Glu Ala Ala Gln Leu Gly Ser Val Phe Ile Leu Val Pro
                  85                  90                  95    
 Val Arg Pro Ser Leu Leu Arg Met Ala Thr Trp Lys Lys Gln Gly Phe
             100                 105                 110        
 Trp Ala Ala Leu Ser Met Val Pro
         115                 120



      <210> 1698
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1698
 Met Ala Pro Trp Thr Leu Ser Arg Cys Cys His Cys Val Met Gly Trp
   1               5                  10                  15    
 Val Pro Val Leu Leu Ile Thr Phe Val Val Ile Trp Ser Tyr Tyr Ala
              20                  25                  30        
 Tyr Val Val Glu Leu Cys Val Phe Thr Ile Phe Gly Asn Glu Glu Asn
          35                  40                  45            
 Gly Lys Thr Val Phe Tyr Leu Asn Ser Thr Cys Pro Ile Leu Lys Arg
      50                  55                  60                
 Asn Val Met Glu Lys Asn Ser Ala Lys Lys Asp Asn Lys Lys Phe
  65                  70                  75                



      <210> 1699
      <211> 271
      <212> PRT
      <213> Homo sapiens


      <400> 1699
 Met Leu Ala Val Leu Thr Ala Phe Ala Arg Ser Arg Arg Leu Leu Cys
   1               5                  10                  15    
 Leu Gly Ser His Phe Gly Arg Thr Ser Gly Ala Leu Gln Pro Thr Ala
              20                  25                  30        
 Ala Leu Trp Glu Pro Leu Ser Gly Leu Ala Lys Thr Gly Ala Val Ser
          35                  40                  45            
 Leu Ser Leu Gln Gly Asp Leu Ser Gln Thr Leu Ser Ser Val Val Gly
      50                  55                  60                
 Arg Asp Arg Asn Ala Lys Lys Gly Glu Met Ile Met Leu Val Asn Val
  65                  70                  75                  80
 Ala Gly Thr His Ala Asn Gly Leu Ser Pro His Asp Gly Glu Asp Gly
                  85                  90                  95    
 Cys Gln Asp Ile Ser His Ile Gly Leu Gly His Thr Gln Val Ile Ser
             100                 105                 110        
 Phe His Phe Asn Tyr Leu Leu Lys Gly Pro Ile Phe Thr Tyr Thr His
         115                 120                 125            
 Ile Pro Arg Asp Trp Arg Thr Ala Thr Ser Ser Glu Ser Leu Cys Val
     130                 135                 140                
 Ser Gly Ser Gly Asn Ala Ile Lys Ala Glu Tyr Phe Glu Ser Pro Phe
 145                 150                 155                 160
 Lys Asn Ser Glu Ala Thr Asn Glu Thr Thr Val Leu Ala Pro His Glu
                 165                 170                 175    
 Thr Ile Phe Arg Ala Glu Asp Leu Ser Val Ile Leu Lys Ala Tyr Val
             180                 185                 190        
 Leu Val Thr Ser Leu Thr Pro Leu Arg Ala Phe Ile His Ser Thr Gly
         195                 200                 205            
 Thr Val Trp Asn Pro Pro Lys Lys Lys Arg Phe Thr Val Lys Pro Ala
     210                 215                 220                
 Ser Pro Trp Ser His Gln Gly Lys Val Tyr Ala Gly Met Arg Met Gly
 225                 230                 235                 240
 Pro Ser Tyr Gly Leu Glu Lys Ser Lys Cys Cys Phe Ser Glu Leu Asp
                 245                 250                 255    
 Pro Gly Ser Val Leu Pro Val Asn Phe Thr Glu Ala Leu Lys Asn
             260                 265                 270    



      <210> 1700
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1700
 Met Leu Thr Ser Ala Phe Leu Phe Ile Leu Thr Leu Pro Phe Ala His
   1               5                  10                  15    
 Ser Ser Phe Lys Leu Asn Val Thr Ser Ser Glu Lys Pro Ser Leu Thr
              20                  25                  30        
 Pro Lys Leu Arg Asn Met Gln Ala Glu Ser Arg Thr Pro Phe Gly Leu
          35                  40                  45            
 Asp Ile Val Glu Glu Ser Leu Tyr Leu Lys Glu Leu Gln
      50                  55                  60    



      <210> 1701
      <211> 177
      <212> PRT
      <213> Homo sapiens


      <400> 1701
 Met Ala Ala Arg His Leu Gly Ala Pro Gly Ala Leu Ala Ala Val Leu
   1               5                  10                  15    
 Gly Thr Pro Ala Leu Pro Arg Arg Arg Ser Arg Pro Leu Met Asn Phe
              20                  25                  30        
 Asp Arg Pro Ala Asn Ser Gly Arg Trp Lys Arg Glu Asn Cys Pro Leu
          35                  40                  45            
 Pro Glu Gly Ala Gly Lys Arg Glu Val Lys Thr Gln Ala Ala Gly Thr
      50                  55                  60                
 Val Arg Asp Ala Arg Val Pro Ser Phe Cys Leu Ala Glu Gly Gln Thr
  65                  70                  75                  80
 Ser Ala Ser Gly Ser Pro His Ile Arg Val Ser Gly Asp Thr Gln Leu
                  85                  90                  95    
 Leu Leu Leu Arg Pro Pro Pro Pro Pro Arg Arg Lys His Gln Thr Ser
             100                 105                 110        
 Gly Asp Asp Gly Asp Ala Ser Leu Val Arg Trp Glu Leu Pro Val Thr
         115                 120                 125            
 Val Leu Gly Ala Leu Ala Gln Arg Ser Ser Ser Ala Leu Thr Gly Ser
     130                 135                 140                
 Ala Asp Val Pro Arg Arg Arg Arg Trp Pro Pro Arg Ser Leu Arg Val
 145                 150                 155                 160
 Thr Gln Phe Phe Thr Pro Ala Arg Thr Ala Gly Arg Arg Gly Lys Ala
                 165                 170                 175    
 Ser
    



      <210> 1702
      <211> 236
      <212> PRT
      <213> Homo sapiens


      <400> 1702
 Met Gly Lys Ser Trp Leu Leu Pro Val Leu Leu Ala Val Tyr Phe Ile
   1               5                  10                  15    
 Leu Val Tyr Trp Glu Glu Leu Ser Val Ala Pro Gly Asn Gly Leu Lys
              20                  25                  30        
 Ser Arg Val His Ile Asn Leu Ser Ser Leu Ser Pro Arg Gly Arg Gly
          35                  40                  45            
 Ile Gly Gly Thr Arg Trp Val Gln Pro Asp Arg Glu Asp Ser Pro Ser
      50                  55                  60                
 Val Val Leu Leu Pro Val Gln Val Trp Glu Asn Ala Gly Ser Val Ser
  65                  70                  75                  80
 Leu Cys Leu Ser Pro Thr Lys Ser Pro Ser Leu Phe Ser Asn Glu Leu
                  85                  90                  95    
 Gln Gly Leu Gly Lys Thr Ile Ser Ser Ser Ala Arg Val Ala Trp Ile
             100                 105                 110        
 Ser Ser Gly Lys Thr Pro Ser His Ser Tyr Thr Ala Leu Trp Ala Ile
         115                 120                 125            
 Leu Leu Thr Lys Ser Ala Ser Val Leu Arg Thr Phe Met Asn Leu Ser
     130                 135                 140                
 His Asp Trp Pro Phe Leu Lys Gly Ser Met Gly Val Ser Tyr Phe Asn
 145                 150                 155                 160
 Ala His Phe Pro Met Gly Lys Glu Gln Ser Val Asn Leu Tyr Cys Met
                 165                 170                 175    
 Thr Leu Gln Gly Lys Val Leu Ile Asp Val Phe Asp Ser Pro Pro Leu
             180                 185                 190        
 Tyr Asp Asp Val Lys Val His Phe Phe Ser Ser Leu Tyr Leu Pro Arg
         195                 200                 205            
 Asn Glu Leu Asp Asn Pro His Lys Gln Lys Ala Trp Thr Ile Tyr Pro
     210                 215                 220                
 Pro Glu Phe Ala Val Glu Ile Leu Phe Gly Lys Lys
 225                 230                 235    



      <210> 1703
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1703
 Met Pro Arg Pro Ala Leu Ala Arg Ala Arg Cys Val His Pro Leu Thr
   1               5                  10                  15    
 Cys Ala His Cys Leu Ala Leu Pro Ser Glu Met Asn Pro Val Pro Gln
              20                  25                  30        
 Met Glu Met Gln Lys Ser Pro Val Phe Cys Val Ala Gln Ala Gly Ser
          35                  40                  45            
 Cys Arg Pro Glu Leu Phe Ile Phe Gly His Leu Arg Glu Asp Cys Phe
      50                  55                  60                
 Gln Ser Trp Ile Arg Asp
  65                  70



      <210> 1704
      <211> 248
      <212> PRT
      <213> Homo sapiens


      <400> 1704
 Met Asp Phe Val Ala Val Ile Lys Val Thr Asn Leu Lys Ile Gly Arg
   1               5                  10                  15    
 Ala Ala Leu Ser Ile Gln Asn Phe Pro Ile Arg Ser Leu Leu Ile Val
              20                  25                  30        
 Thr Phe Leu Trp Thr Leu Leu Asp Val Glu Pro Gly Glu Leu Val Glu
          35                  40                  45            
 Pro Thr Gln Thr Ser Asp Leu Gln Lys Cys Glu Val Gln Thr Gln Ser
      50                  55                  60                
 Glu Glu Arg Glu Asp Leu Ala Ala Ser Gly Glu Lys Leu Lys Trp Met
  65                  70                  75                  80
 Ser Asn Lys Leu Ser Asn Gln Glu Pro Pro Ser Ala Ala Pro Arg Phe
                  85                  90                  95    
 Ala Asp Lys Glu Val Lys Ala Thr Glu Glu Lys Trp Arg Glu Lys Gly
             100                 105                 110        
 Arg Leu Thr Trp Gly Pro Lys Ala Gln Pro Asp Ser Arg Phe Gly Leu
         115                 120                 125            
 Gly Arg Cys Leu Ala Pro Arg Ala Gln Ala Glu Gly Ala Gly Ala Ala
     130                 135                 140                
 Gln Ser Arg Asp Ser Thr Tyr Arg Gly Leu Glu Thr Pro Leu Ala Ala
 145                 150                 155                 160
 Arg Pro Pro Arg Cys Ala Pro Cys Cys His Arg Ser Glu Arg Arg Arg
                 165                 170                 175    
 His Ala Pro Arg Cys Leu Leu Val Leu Glu Thr Glu Gly Asn Leu Arg
             180                 185                 190        
 His Arg Arg Gly Lys Gly Asn Val Thr Thr Glu Thr Lys Ile Gly Met
         195                 200                 205            
 Met Gln Ser Gln Ala Asn Glu Trp Gln Gln Pro Pro Glu Ala Gly Arg
     210                 215                 220                
 Gly Lys Glu Gly Ile Leu Ser Lys Ser Phe Ser Arg Lys His Asn Pro
 225                 230                 235                 240
 Ala Phe Ile Leu Ile Ser Val Gln
                 245            



      <210> 1705
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 1705
 Met Arg Phe Cys Gly Phe Pro Gly Leu Gly Lys Ala Gly Lys Trp Trp
   1               5                  10                  15    
 Leu Val Ala Ala Asn Trp Ala Ala Leu Lys Gly Asn Pro Arg Gln Val
              20                  25                  30        
 Asp Tyr Leu Gly Lys Gln Leu Glu Gln Trp Ser Trp Ala Ala Ser Pro
          35                  40                  45            
 Arg Ser Ser Arg Glu Leu Lys Met Arg Ser Gly Asp Arg Leu Arg Met
      50                  55                  60                
 Tyr Glu Pro Cys Gly Ser Arg Ala Leu Phe Ser Leu Leu Arg Asn Arg
  65                  70                  75                  80
 Asn Asn Thr Cys Leu Thr Glu Leu Leu Lys Ser Ser Thr Glu Ile Met
                  85                  90                  95    
 Thr Ala Ser Val Asn Cys Lys Ala Met Arg Asp Val Ala Asp Arg Ser
             100                 105                 110        
 Arg Val Ala Val Thr Leu Ser Trp Ser Tyr Thr Val Glu Lys Glu Ala
         115                 120                 125            
 Leu Thr Gln Thr Arg Glu Ile Phe Pro Cys Lys Arg Cys Pro His Val
     130                 135                 140                
 Val Gly Thr Ser Tyr Phe Lys Glu Asp Ile Pro Val Glu Tyr Lys Ile
 145                 150                 155                 160
 Ile Cys Val Thr Met Glu Arg Asp Gln Gly Ser Thr Leu Lys Phe Gln
                 165                 170                 175    
 Gly Cys Leu Ser Pro Pro Lys Thr Gly Leu Leu Ala Ala Val Glu Gly
             180                 185                 190        
 Arg Gly Thr Glu Asp Arg Arg Thr Trp Leu Ala Arg Pro Ala Leu Ala
         195                 200                 205            
 Val Thr Thr Val Met
     210            



      <210> 1706
      <211> 230
      <212> PRT
      <213> Homo sapiens


      <400> 1706
 Met Glu Val Ala Ala Phe Gly Lys Gln Lys Leu Arg Val Ala Trp Ser
   1               5                  10                  15    
 Leu Gln Val Leu Phe Arg Leu Met Ala Val Glu Ile Trp Asn Ser Lys
              20                  25                  30        
 Pro Ala Val Ile His Lys Asn Trp Cys Arg Pro Ala Gly Gln Ala Asn
          35                  40                  45            
 Tyr Arg Asn Lys Asp Val Pro Phe His Ser Asp Thr Arg Gly Leu Ala
      50                  55                  60                
 Leu Ser Arg Gln Leu Lys Asn Leu Arg Val Thr Lys Gly Pro Glu Tyr
  65                  70                  75                  80
 Gln Glu Glu Gly Leu Glu Met Glu Arg Ser Gly Ala Gln Ile Glu Asn
                  85                  90                  95    
 Gln Leu Glu Lys Gly Ser Leu Val Leu Asn Ile Lys Thr Tyr Asn Lys
             100                 105                 110        
 Gly Glu Arg Thr Gly Gln Asn Ala Ser Val Glu Met Ser Lys Thr Glu
         115                 120                 125            
 Gly Ala Gly Gly Cys Trp Gly Lys Glu Gln His Pro Val Gly Leu Pro
     130                 135                 140                
 Arg Thr Thr Gly Pro Met Gln Ser Ser Val Pro Pro Gly Ser Gly Gly
 145                 150                 155                 160
 Met Val Ser Gly Ala Ser Pro Ala Gly Pro Gly Phe Leu Gly Ser Gln
                 165                 170                 175    
 Pro Gln Ala Ala Ile Met Lys Gln Met Leu Ile Asp Gln Arg Ala Gln
             180                 185                 190        
 Leu Ile Glu Gln Gln Lys Gln Gln Phe Leu Arg Glu Gln Arg Gln Gln
         195                 200                 205            
 Gln Gln Gln Gln Gln Gln Gln Ile Leu Ala Glu Gln Tyr Leu Lys Glu
     210                 215                 220                
 Gln Asp Ser Ala Asp Val
 225                 230



      <210> 1707
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 1707
 Met Ala Arg Pro His Thr His Leu Leu Met Gln Pro Leu Leu Leu Cys
   1               5                  10                  15    
 Thr Trp Leu Ala Leu Gly Arg His Gly Ile Trp Thr Ser Ser Glu Arg
              20                  25                  30        
 Gln Ala Gln Pro Ala Arg Pro Ser Gly Trp Lys Glu Pro Ser Gly Pro
          35                  40                  45            
 Lys Gln Asn Ser Gly Tyr Val Ser Tyr Ile Asp Arg Arg Phe Pro Leu
      50                  55                  60                
 Lys Thr Gly Ser Arg Val Pro Ile Leu Asp Asp Glu Gly Asn Lys Ser
  65                  70                  75                  80
 Arg Thr Asp Ala Asn Tyr Asp Phe Glu Pro Leu Glu Pro Val Asn Ser
                  85                  90                  95    
 Val Ser Lys Gln Leu Met
             100        



      <210> 1708
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 1708
 Met Val Pro Leu Cys Gln Val Arg Val Ala Gly Val Arg Ala Gly Leu
   1               5                  10                  15    
 Ala Leu Val Ser Arg Thr Ser Pro Leu Ala Pro Asn Leu Ala Gly Val
              20                  25                  30        
 Leu Gly Ser Gly Ala Pro Pro Pro Pro Pro Pro Gly Pro Ser Cys Leu
          35                  40                  45            
 Arg Ala Leu Leu Arg Leu Pro Gln Gln Lys Ser Gly Pro Leu Arg Glu
      50                  55                  60                
 Leu Leu Ser Ala His Gly Ser Lys Asp Gly Leu Val Leu Lys Ala Pro
  65                  70                  75                  80
 Pro Pro Phe Met Thr Thr Ser Phe Pro Asp Tyr Ser Phe
                  85                  90            



      <210> 1709
      <211> 255
      <212> PRT
      <213> Homo sapiens


      <400> 1709
 Met Lys Ala Leu Leu Ala Leu Pro Leu Leu Leu Leu Leu Ser Thr Pro
   1               5                  10                  15    
 Pro Cys Ala Pro Gln Val Ser Gly Ile Arg Gly Asp Ala Leu Glu Arg
              20                  25                  30        
 Phe Cys Leu Gln Gln Pro Leu Asp Cys Asp Asp Ile Tyr Ala Gln Gly
          35                  40                  45            
 Tyr Gln Ser Asp Gly Val Tyr Leu Ile Tyr Pro Ser Gly Pro Ser Val
      50                  55                  60                
 Pro Val Pro Val Phe Cys Asp Met Thr Thr Glu Gly Gly Lys Trp Thr
  65                  70                  75                  80
 Val Phe Gln Lys Arg Phe Asn Gly Ser Val Ser Phe Phe Arg Gly Trp
                  85                  90                  95    
 Asn Asp Tyr Lys Leu Gly Phe Gly Arg Ala Asp Gly Glu Tyr Trp Leu
             100                 105                 110        
 Gly Leu Gln Asn Met His Leu Leu Thr Leu Lys Gln Lys Tyr Glu Leu
         115                 120                 125            
 Arg Val Asp Leu Glu Asp Phe Glu Asn Asn Thr Ala Tyr Ala Lys Tyr
     130                 135                 140                
 Ala Asp Phe Ser Ile Ser Pro Asn Ala Val Ser Ala Glu Glu Asp Gly
 145                 150                 155                 160
 Tyr Thr Leu Phe Val Ala Gly Phe Glu Asp Gly Gly Ala Gly Asp Ser
                 165                 170                 175    
 Leu Ser Tyr His Ser Gly Gln Lys Phe Ser Thr Phe Asp Arg Asp Gln
             180                 185                 190        
 Asp Leu Phe Val Gln Asn Cys Ala Ala Leu Ser Ser Gly Ala Phe Trp
         195                 200                 205            
 Phe Arg Ser Cys His Phe Ala Asn Leu Asn Gly Phe Tyr Leu Gly Gly
     210                 215                 220                
 Ser His Leu Ser Tyr Ala Asn Gly Ile Asn Trp Ala Gln Trp Lys Gly
 225                 230                 235                 240
 Phe Tyr Tyr Ser Leu Lys Arg Thr Glu Met Lys Ile Arg Arg Ala
                 245                 250                 255



      <210> 1710
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 1710
 Met Leu Leu Gly Thr Ala Ala Ala Ser Gln Leu Trp Leu Trp Ala His
   1               5                  10                  15    
 Ala Ser Leu Arg Ser Gln Gly Pro Gly Ser Pro Gln Cys Pro Gln Ala
              20                  25                  30        
 Gln Lys Cys Leu Phe Leu Leu Pro Val Leu Phe Pro Leu Leu Val Pro
          35                  40                  45            
 Ala Pro Val Trp Ser Lys Val Val Ala Lys Pro Gly Arg Cys Cys Asn
      50                  55                  60                
 Leu Ala Arg Leu Trp Val Leu Thr Ser Thr Gly Met Gly Ser Glu Val
  65                  70                  75                  80
 Val Val
        



      <210> 1711
      <211> 343
      <212> PRT
      <213> Homo sapiens


      <400> 1711
 Met Leu Ser Trp Ala Ser Thr Gly Gly Leu Arg Leu Met Ala Ala Met
   1               5                  10                  15    
 Ala Phe Phe Ile Cys Val Gly Arg Val Val Ser Gln Trp Glu Asp Asp
              20                  25                  30        
 Asp Glu Gly Glu Asp Met Thr Thr Lys His Gly Phe Gly Phe Leu Leu
          35                  40                  45            
 Gln Leu Leu Leu Gly Ser Tyr Gln Gly Ile Ser Ser Ala Cys Glu Leu
      50                  55                  60                
 Leu Gly Ala Arg Leu Arg Leu Lys Asn Asn Asn Asn Asn Asn Asn Asn
  65                  70                  75                  80
 Asn Asn Asn Asn Asn Asn Asn Lys Val Leu Ala Gly Cys Phe Tyr Val
                  85                  90                  95    
 Phe Ile Lys Pro Ala Leu Phe Thr Ser Glu Thr Leu Met Lys Thr Thr
             100                 105                 110        
 Ala Ala Arg Ala Pro Cys Ile Leu Val Gly Leu Cys Asp Tyr Phe Trp
         115                 120                 125            
 Pro Met Asp Ala Trp Leu Leu Asp Pro Thr Asp Gly Phe Ser Pro Val
     130                 135                 140                
 Thr Pro Pro Ala Phe Tyr Leu Asp Thr Ser Arg Gly Ala Arg Val Ala
 145                 150                 155                 160
 Leu Ala Lys Lys Glu Ala Trp His Pro Arg Arg Pro Gly Pro Ala Ala
                 165                 170                 175    
 Ala Ala Ala Gly Ala Glu Leu Gly Leu Gly Lys Pro Ala Asp Arg Val
             180                 185                 190        
 Leu Arg Arg Ser Ser Thr Ser Arg Ala Ala Pro Pro Pro Arg Val Pro
         195                 200                 205            
 Glu Ser Ala Ala Leu Gly Ala Gly Pro Ala Pro Ala Pro Arg Leu Pro
     210                 215                 220                
 Arg Lys Arg Gly Gly Pro Ser Pro Gly Arg Glu Ala Ala Thr Ala Glu
 225                 230                 235                 240
 Leu Arg Thr Leu Trp Phe Asn Lys Phe Leu Val Arg Glu Asp Ala Ala
                 245                 250                 255    
 Gln Leu Val Glu Ser Glu Ser His Gly Val Lys Leu Ala Leu Pro Ala
             260                 265                 270        
 His Ala Asp Leu Gly Leu Pro Gly Cys Pro Gly Arg Gln Arg Pro Pro
         275                 280                 285            
 Leu Ser Ser Trp Leu Thr Pro Ile Pro Pro Glu Glu Asp Val Cys Gln
     290                 295                 300                
 Gly Arg Arg Val Gln Leu Leu Ala Ser Ala Leu Asp Asn Pro Gln Pro
 305                 310                 315                 320
 Gln Pro Leu Pro Ser Leu Leu Pro Cys Ser Gln Pro His Ala Gly Gly
                 325                 330                 335    
 Ala Thr Trp Asp Thr Ser Ser
             340            



      <210> 1712
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 1712
 Met Gln Ser Leu Gly Val Val Leu Tyr Val Leu Val Cys Gly Ala Leu
   1               5                  10                  15    
 Pro Phe Asp Gly Ser Thr Leu Gln Asn Leu Arg Ala Arg Val Leu Ser
              20                  25                  30        
 Gly Lys Phe Arg Ile Pro Phe Phe Met Ser Thr Asp Leu Leu Tyr Ser
          35                  40                  45            
 Val Phe Ala Ala Leu Val Asn Ser Ile Thr Ile
      50                  55                



      <210> 1713
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 1713
 Met Lys Leu Leu Gly Ile Ile Gln Arg Gln Pro Leu Leu Val Ile Cys
   1               5                  10                  15    
 Val Ala Leu Gly Phe Val Leu Ala Val Thr Met Thr Arg Glu Ala Ile
              20                  25                  30        
 Asp Glu Phe Arg Arg Phe Gln Arg Asp Lys Glu Val Asn Ser Gln Leu
          35                  40                  45            
 Tyr Ser Lys Leu Thr Glu Ile Phe Val Arg Thr Leu Ala Glu Tyr Lys
      50                  55                  60                
 Asn Gly Arg Glu Thr Leu Glu Thr Ile His Asp Lys Glu Tyr Thr Leu
  65                  70                  75                  80
 Tyr Lys Asn Ser Val Glu Lys Ser Val Asp Asn Thr Ala Thr Ala Cys
                  85                  90                  95    
 Asn Asn Lys Ile Asn Pro Glu Glu Gly Glu Ile Ala Asn Phe Gln Asn
             100                 105                 110        
 Tyr Gln Ile Ile Ile Val Ser Arg Val Ile Gly Met Ala Cys Gly Glu
         115                 120                 125            
 His Ser Val Asn Cys Gly Ser Gln Glu Arg Lys Lys Phe Gln Ile Gln
     130                 135                 140                
 Met Lys Val Leu Ser Leu Val
 145                 150    



      <210> 1714
      <211> 294
      <212> PRT
      <213> Homo sapiens


      <400> 1714
 Met Met Val Trp Trp Phe Phe Ser Leu Leu Asn Leu Ile Thr Ser Asn
   1               5                  10                  15    
 Gly His Thr Met Asp Arg Cys Arg Gln Gly Gly Gly Glu Tyr Glu Val
              20                  25                  30        
 Phe Ala Val Leu Gln Gly Arg Thr Leu Phe Leu Glu Arg Tyr Ile Phe
          35                  40                  45            
 Asn Gly Ser Gly Tyr Ile Cys Ser Pro Lys Ala Leu Asn Lys Asp Ile
      50                  55                  60                
 His Ser Ser Ala Ile Pro Ser Ser His Arg Leu Lys Ser Asp Glu Leu
  65                  70                  75                  80
 Cys Ser Arg Arg Asn Gln Phe His Gly Lys Thr Gly Ser Val Val Ala
                  85                  90                  95    
 Gly Ser Leu Glu Pro Lys Leu Thr Cys Lys Trp Arg Arg Leu Tyr Leu
             100                 105                 110        
 Phe Leu Arg Ile Gly Phe Val Lys Asp Glu Arg Arg Lys Gln Glu Gly
         115                 120                 125            
 Pro Gly Asn Pro Lys Ser Met Ser Gly Asn Gly Lys Glu Gly Glu Glu
     130                 135                 140                
 Gly Lys Pro Pro Arg Arg Glu Arg Gly Lys Gln Lys Asn Ile Lys Arg
 145                 150                 155                 160
 Glu Asn Ser Arg Arg Tyr Lys Ala Thr Arg Gly Glu Asn Thr Leu Gly
                 165                 170                 175    
 Glu Glu Arg Arg Lys Gly Thr Val Glu Val Glu Val Lys Val Lys Val
             180                 185                 190        
 Val Val Met Val Glu Glu Asp Lys Glu Glu Asp Asp Glu Phe Ser Leu
         195                 200                 205            
 Gly Gln Thr Lys Phe Asn Ser Leu Glu Ser Ile Leu Gly Asn Arg Val
     210                 215                 220                
 Arg Leu His Gln Lys Lys Thr Lys Lys Lys Lys Lys Lys Lys Lys Lys
 225                 230                 235                 240
 Lys Lys Lys Lys Glu Glu Glu Glu Glu Glu Lys Glu Glu Glu Glu Glu
                 245                 250                 255    
 Glu Glu Gly Glu Asp His Gln Thr Pro Lys Cys Trp Arg Ile Gln Gly
             260                 265                 270        
 Pro Val Leu Ser Leu Leu Leu Phe Ser Val Asn Thr Leu His Leu Cys
         275                 280                 285            
 Asp Pro Thr Gln Ser His
     290                



      <210> 1715
      <211> 178
      <212> PRT
      <213> Homo sapiens


      <400> 1715
 Met Pro Gly Ser Ala Tyr Phe Lys Thr Leu Ile Ser Thr Ile Trp Ile
   1               5                  10                  15    
 Thr Trp Trp Leu Ala Ala Ile Phe Trp Phe Ser Gly Pro Gln Ser Tyr
              20                  25                  30        
 His Pro Gly Leu Ser Leu Val Ile Ser Met Ser Gly Arg Glu Asp Ser
          35                  40                  45            
 Gln Ser Thr Glu Ala Ala Ala Gly Ile Glu Met Ser Pro Thr His Ile
      50                  55                  60                
 Ser Val Cys Trp Val Ser Ser Met Pro Met Ser Ser Val Lys Gly Ala
  65                  70                  75                  80
 Val Ala Cys Arg Leu Trp Met Pro Phe Arg Lys Ala Ala Ser Gln Pro
                  85                  90                  95    
 Leu Val Ser Ser Lys Asn Glu Glu Met Glu Glu Lys Lys Lys Gln Glu
             100                 105                 110        
 Glu Lys Glu Glu Glu Glu Arg Lys Lys Gly Arg Glu Arg Gly Arg Glu
         115                 120                 125            
 Glu Glu Glu Glu Glu Arg Lys Lys Gly Arg Glu Arg Gly Arg Glu Glu
     130                 135                 140                
 Glu Glu Glu Glu Glu Lys Arg Lys Glu Lys Lys Arg Asn His Gln Val
 145                 150                 155                 160
 Asn Tyr Glu Val Gly Gly Asp Gln Thr Leu Asn Ser Ala Ser Arg Cys
                 165                 170                 175    
 Leu Glu
        



      <210> 1716
      <211> 231
      <212> PRT
      <213> Homo sapiens


      <400> 1716
 Met Ala Ser Arg Trp Ala Gln Ala Leu Cys Leu Leu Gly Gly Thr Val
   1               5                  10                  15    
 Pro Gly Gln Pro Thr Pro Leu Ser Ala Gly Glu Ala Ala Arg Ser Gly
              20                  25                  30        
 Gln Ser Leu Ser Asn Gln Phe Gln Pro Val Ser Ser Val Val Lys Trp
          35                  40                  45            
 Asp Glu Arg Ala Tyr Pro Gln Lys Asp Tyr Ala Leu Gly Gly Arg Trp
      50                  55                  60                
 Ala Gln Asn Asp Glu Asp Gly Ala Asn Leu Asn Pro Thr Cys Asn Leu
  65                  70                  75                  80
 Glu Met Ile Pro Ala Asn Pro Glu Ser Cys Ile Arg Phe Leu Gly Glu
                  85                  90                  95    
 Asp Arg Ser Met Ile Arg Arg Ala Ala Met Thr Ile Trp Glu Arg Glu
             100                 105                 110        
 His Pro Pro Gly Gln Asn Val Pro Ala Ala Glu Gln Lys Leu Ala Ala
         115                 120                 125            
 Thr Asp Pro Gln Trp Asp Ser Asn Asn Ala Ala Tyr Trp Arg Asn Met
     130                 135                 140                
 Gln Asp Leu Gly Glu Leu Ile Ile Lys Gly Thr Gln Lys Ser Val Phe
 145                 150                 155                 160
 Arg Ile Gln Asn Ile Pro Lys Ala Phe Tyr Ile Gln Gln Gly Lys Asp
                 165                 170                 175    
 Glu Gly Pro Thr Glu Phe Leu Glu Arg Leu Lys Glu Gln Ala Arg Ile
             180                 185                 190        
 Tyr Ala Gly Leu Gly Leu Glu Asp Pro Leu Gly Gln Gly Met Leu Lys
         195                 200                 205            
 Leu His Phe Val Thr Asn Ser Trp Pro Asp Ile Thr Lys His Val Ile
     210                 215                 220                
 Glu Asn Arg Glu Leu Glu Arg
 225                 230    



      <210> 1717
      <211> 85
      <212> PRT
      <213> Homo sapiens


      <400> 1717
 Met Ala Ser Arg Trp Ala Gln Ala Leu Cys Leu Leu Gly Gly Thr Val
   1               5                  10                  15    
 Pro Gly Gln Pro Thr Pro Leu Ser Ala Gly Glu Ala Ala Ser Leu Val
              20                  25                  30        
 Gly Cys Asp Arg Ile Arg Leu Asp Leu Ala Glu Tyr Gly Phe Thr Phe
          35                  40                  45            
 Gln Ser Val Lys Glu Lys Phe Val Asp Phe Arg Lys Ala Phe Gly Val
      50                  55                  60                
 Leu Gly Asn Cys Ser Cys Gln Leu Leu Lys Met Pro Cys Val Cys Pro
  65                  70                  75                  80
 His Lys Gly Met Gln
                  85



      <210> 1718
      <211> 267
      <212> PRT
      <213> Homo sapiens


      <400> 1718
 Met Ala Glu Ser Lys Ala Glu Met Ala Gly Pro Asn Thr Arg Ile Trp
   1               5                  10                  15    
 His Leu Leu Ser Arg Phe Leu Leu Ser Cys Phe Phe Gly Ala Phe Gln
              20                  25                  30        
 Thr Ala Glu Phe Gln Cys Cys Pro Leu Ala Gly Arg Cys Leu Arg His
          35                  40                  45            
 Gly Lys Gly Phe His Ile Ser Cys Gly Ala Gly Thr Gly Gln Gly Ala
      50                  55                  60                
 Gly Glu Glu Lys Val Thr Leu Thr Asp Ala Val Pro Ala Leu Trp Ser
  65                  70                  75                  80
 Ser Trp Val Gly Ser Lys Ala Ile Val Thr Gln His Gly Asn Asp Ser
                  85                  90                  95    
 Leu Glu Gln Leu Asn Lys Gln Pro His Ile Leu Ile Val Asn Thr Glu
             100                 105                 110        
 Thr Leu Lys Val Val Asn Ser Pro Glu Leu Thr Lys Ser Arg Lys Leu
         115                 120                 125            
 Glu Ala Asn Val Pro Cys Gly Ala Glu Ala Ala Ser Ser Leu Ser Ser
     130                 135                 140                
 Pro Ala Leu Val Arg Gly Asn Trp Asn Ile Leu Gly Val Val Val Met
 145                 150                 155                 160
 Val Cys Leu Gly Gln Ser Glu Val Leu Val Arg Arg Lys Val Lys Glu
                 165                 170                 175    
 Asp Thr Leu Phe Leu Asn His Ile Asp Pro Leu Trp Val Ser Gln Gly
             180                 185                 190        
 Lys Ala Gly Ser Met Pro Arg Arg Ala His Gly Thr Gln Gly Ala Val
         195                 200                 205            
 Glu Thr Tyr Ala Val Asn Arg Glu Lys Pro Ser Thr Gln Arg His His
     210                 215                 220                
 Gly Ile Tyr His Val Ala Ile Gln Lys Ala Phe Gly Glu Leu Leu Ile
 225                 230                 235                 240
 Tyr Ser Thr Val Lys Asn Asn Leu Leu Arg Asn Ala Ala Ser Thr Gln
                 245                 250                 255    
 Gln Pro Ala Ala Leu Asn Asn Gln Lys Thr Lys
             260                 265        



      <210> 1719
      <211> 96
      <212> PRT
      <213> Homo sapiens


      <400> 1719
 Met Val Val Pro Ile Phe Gln Val Leu Thr Leu Cys Ser Leu Pro Ser
   1               5                  10                  15    
 Ala Phe Cys Ala Thr Ser Ile Asn Asp His Lys Asn Pro Ser Glu Ala
              20                  25                  30        
 Ala Leu Leu Thr Ala Cys Pro Ile Pro Gln Asp Trp Arg Val Ala Thr
          35                  40                  45            
 Ala Gly Glu Pro Lys Gly Thr Thr Arg Leu Pro Gly Pro Pro Ala Pro
      50                  55                  60                
 Gly Ser Ala Gly Phe Gly Lys Arg Glu Lys Glu Gln Lys Ala Lys Leu
  65                  70                  75                  80
 Pro Gly Gly Arg Arg Pro Ser Ala Ala His Ser Ala Asn Ala Thr Glu
                  85                  90                  95    





      <210> 1720
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1720
 Met Lys Cys His Leu Cys Cys Phe Leu Leu Val Lys Val Gln Leu Thr
   1               5                  10                  15    
 His Leu Thr His Ile Phe Val Ile Tyr Ala Phe Leu Tyr Gly Asn Phe
              20                  25                  30        
 Leu Ala Leu Thr Tyr Phe Trp Leu Trp Asn Leu Ser Thr Met Ile Ser
          35                  40                  45            
 Ser Pro Cys Trp Ile Ile Pro Asp Ser Asn Ser Arg Met Leu His Ser
      50                  55                  60                
 Leu Lys His Leu Asp Ala
  65                  70



      <210> 1721
      <211> 371
      <212> PRT
      <213> Homo sapiens


      <400> 1721
 Met Gln Ser Pro Ser Arg Gly Leu Arg Gln Asn Thr Cys Val Cys Leu
   1               5                  10                  15    
 Leu Leu Leu Ser Ile Ala Gln Ser Gly Ser Glu Gly Arg Thr Trp Gln
              20                  25                  30        
 Val Val Leu Cys Val Arg Asn Ala Ala Met Asp Cys Asp Gly Thr Pro
          35                  40                  45            
 Glu Asn Lys Val Leu Leu Leu Gln Gly Lys Asn Thr Lys Glu Glu Thr
      50                  55                  60                
 Glu Val Leu Pro Lys Pro Pro Pro Thr Ile Asn Trp Lys Lys Asp Lys
  65                  70                  75                  80
 Gly Tyr Thr Ile Ala Met Glu Pro Cys Leu Arg Gln Ala Ala Leu Glu
                  85                  90                  95    
 Gly Glu Leu Phe Ala Cys Leu Val Met Gln Asp Arg Gln Gly Asn Gln
             100                 105                 110        
 Val Tyr Glu Pro Ile Ser Ser Asp Ala Asp Lys Glu Ile Arg Lys Ser
         115                 120                 125            
 Ile Arg Glu Asn Arg Gly Thr Ser Pro Leu Thr Lys Gly Leu Ile Glu
     130                 135                 140                
 Thr Ile Ala Asp Asn Leu His Met Thr Pro Trp Asp Trp Ser Val Leu
 145                 150                 155                 160
 Ala Lys Thr Thr Leu Lys Ile Ala Val Ser Asp Tyr Ala Gly His Ile
                 165                 170                 175    
 Glu His Ala Leu Pro Ala Asp Lys Leu Leu Gln Phe Leu Pro His Thr
             180                 185                 190        
 Pro Val Val Met Pro Thr Lys Val Val His Phe Pro Ile Ser Asn Thr
         195                 200                 205            
 Leu Met Leu Phe Ala Asp Gly Ser Ser Lys Asn Gly Lys Ala Ala Ile
     210                 215                 220                
 Gly Gly Asn Pro Gln Gly Gln Ala Ile Glu His Gly His Ser Thr Leu
 225                 230                 235                 240
 Asn Met Leu Asn Met Leu Thr Arg Ser Gly Phe Thr Phe Thr Gln Arg
                 245                 250                 255    
 Ala Glu Val Gly Ala Leu Ile Leu Ala Leu Glu Thr Phe Ser Phe Gln
             260                 265                 270        
 Pro Ile Asn Ile Asp Ser Asp Ser Ala Tyr Ala Val Tyr Leu Leu Gln
         275                 280                 285            
 Asn Leu Glu Thr Ala Leu Ile Glu Ser Ala Leu Glu Pro Asn Leu Tyr
     290                 295                 300                
 Ala Leu Phe Leu Gln Thr Ser Ala Ile Ala Asp Gln Ser Arg Cys Ile
 305                 310                 315                 320
 Lys Ser Tyr His Gly Val Ala Arg Thr Gln Pro Ser Arg Arg Asn Glu
                 325                 330                 335    
 Gly Asn Asp Pro Thr Gly Pro Ala Ala Pro Asp Asp Ala Thr Ser Leu
             340                 345                 350        
 Asp Asp Thr Ser Pro Gly His Tyr Leu Gly Asp Ala Glu Asp Asp Asn
         355                 360                 365            
 Pro Gly Gly
     370    



      <210> 1722
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 1722
 Met Val Phe His Thr Ala Leu Pro Leu Thr Thr Ala Leu Thr Leu Arg
   1               5                  10                  15    
 Leu Lys Lys Cys Gly Thr Val Leu Ile Leu Met Glu Phe Thr Gly Leu
              20                  25                  30        
 Thr Met Phe Pro Ile Ile Leu Lys Gln Gly Trp Gly Lys Val Ile Gln
          35                  40                  45            
 Arg Ala Val Tyr Ala Leu Asn Gln His Pro Ile Tyr Gly Thr Val Ser
      50                  55                  60                
 Pro Ile Ala Arg Ile His Arg Ser Arg Asn Gln Gly Val Glu Val Glu
  65                  70                  75                  80
 Val Ala Pro Leu Ser Ile Thr Ser Asn Asp Thr Leu Ala Lys Phe Leu
                  85                  90                  95    
 Phe Pro Val Pro Met Thr Leu Tyr Ser Ala Gly Leu Glu Val Ser Val
             100                 105                 110        
 Pro Glu Gly Gly Met Leu Pro Thr Gly Glu Thr Ile Thr Ile Gln Phe
         115                 120                 125            
 Asn Trp Lys Leu Arg Leu Pro Pro Gly His Phe Ser Tyr Leu Ser Gln
     130                 135                 140                
 Gln Ala Lys Lys Gly Val Thr Val Leu Val Gly Val Ile Phe Pro Asp
 145                 150                 155                 160
 Tyr Gln Asp Glu Ile Ser Leu Leu His His Ser Glu Ala Lys Glu Glu
                 165                 170                 175    
 Tyr Val Trp Asn Thr Gly Val Arg Ala Ser Leu Ser Phe Thr Met Pro
             180                 185                 190        
 Cys Asp Glu Gly His Trp Glu Thr Ala Thr Ala Leu Phe Arg Gln Asn
         195                 200                 205            
 Cys Lys Trp Val Pro Asp Pro Ser Gly Met Lys Val Trp Val Thr Pro
     210                 215                 220                
 Pro Gly Lys Lys Pro Arg Pro Ala Glu Val Leu Ala Glu Val Lys Gly
 225                 230                 235                 240
 Asn Thr Glu Trp Val Val Glu
                 245        



      <210> 1723
      <211> 165
      <212> PRT
      <213> Homo sapiens


      <400> 1723
 Met Ala Glu Ala Asp Ser Arg Ser Tyr Phe Phe Leu Pro Phe Ile Leu
   1               5                  10                  15    
 Ser Leu Ile Leu Leu Lys Gly Asp Leu Gly Leu Ser Phe Met Asp Arg
              20                  25                  30        
 Ser Asn Ile Leu Ala Leu Arg Leu Leu Arg Val Asn Trp Met His Leu
          35                  40                  45            
 Glu Tyr Gly Ile Phe Asn Leu His Glu Asp Ser Met Ala Tyr Ala Trp
      50                  55                  60                
 Ser Ala Gln Asn Arg Ala Arg His Thr Gly Asn Ala His Glu His Arg
  65                  70                  75                  80
 Leu Ser His Ser Ala Ala Lys Gly Thr Gly Gly Leu Val Lys Gly Lys
                  85                  90                  95    
 Lys Leu Ala Glu Gly Pro Gln Ile Pro Gln Arg His Ala Thr Val Leu
             100                 105                 110        
 Arg Leu Thr Leu Lys Ser Leu His Ala Asp Glu Ser His Cys Pro Asn
         115                 120                 125            
 Leu Phe Gln Arg Gln Ala Leu Pro Gln Leu Val Asn Ser Tyr Tyr His
     130                 135                 140                
 Pro Gly Asp Lys Glu Pro Ala Lys Leu Thr Val Val Gly Ile Lys Pro
 145                 150                 155                 160
 His Pro Gln Gly Lys
                 165



      <210> 1724
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 1724
 Met Gly Ser Thr Ser Arg Pro Leu Leu Ile Phe Thr Thr Cys Leu Lys
   1               5                  10                  15    
 Leu Phe Ser Gln Leu Val Val Asn Ala Ser Arg Leu Ala Thr His Pro
              20                  25                  30        
 Ser Gly Gln Trp Ala Pro Ile Trp Pro Met Ala Gly Pro Glu Met Pro
          35                  40                  45            
 Ser Lys Ser Gln Gly Leu Glu Leu Gly Pro His Lys Ala Ala Pro Val
      50                  55                  60                
 Pro Gln Ala Thr Met Asp Leu His Leu Asp Ala Leu Arg Ser His Glu
  65                  70                  75                  80
 Ser Ala Ser Asn Ser Ser Ser Gly Ser Ser Ser Arg Gly Asp Gln Lys
                  85                  90                  95    
 Gly His Tyr Leu Cys Met Asn Asn Asn Gly Asn Gln Asp Thr Met Leu
             100                 105                 110        
 Gly Ser Pro Trp Cys Gly His Phe Pro Ser His Lys Pro His Thr Gly
         115                 120                 125            
 Leu Pro Leu Arg Leu Phe His Arg Cys Thr Ile Thr Ser Asn Val Cys
     130                 135                 140                
 Ile Ala Ala Pro Ser Ser Gln
 145                 150    



      <210> 1725
      <211> 497
      <212> PRT
      <213> Homo sapiens


      <400> 1725
 Met Val Phe Phe Thr Thr Leu Phe Ile Leu Val Gly Ala Pro Ala Ala
   1               5                  10                  15    
 Pro Ser Val Lys Pro Gln Gln Gln Gln Glu Pro Leu Ala Ala Val Arg
              20                  25                  30        
 Pro Pro Leu Gly Asp Leu Ser Thr Lys Asp Leu Gly Asp Pro Ser Met
          35                  40                  45            
 Asp Lys Ala Ala Val Lys Ile Gln Ala Ala Phe Lys Gly Tyr Lys Val
      50                  55                  60                
 Arg Lys Glu Met Lys Gln Gln Glu Gly Pro Met Phe Ser His Thr Phe
  65                  70                  75                  80
 Gly Asp Thr Glu Ala Gln Cys Val Val Ala Ser Lys Ala Asp Val Arg
                  85                  90                  95    
 Ala Arg Trp Leu Lys Asp Gly Val Glu Leu Thr Asp Gly Arg His His
             100                 105                 110        
 His Ile Asp Gln Leu Gly Asp Gly Thr Cys Ser Leu Leu Ile Thr Gly
         115                 120                 125            
 Leu Gly Arg Ala Asp Ala Gly Cys Tyr Thr Cys Gln Val Ser Asn Lys
     130                 135                 140                
 Phe Gly Gln Val Thr His Ser Ala Cys Val Val Val Ser Gly Ser Glu
 145                 150                 155                 160
 Ser Glu Ala Glu Ser Ser Ser Gly Gly Glu Leu Asp Asp Ala Phe Arg
                 165                 170                 175    
 Arg Ala Ala Arg Arg Leu His Arg Leu Phe Arg Thr Lys Ser Pro Ala
             180                 185                 190        
 Glu Val Ser Asp Glu Glu Leu Phe Leu Ser Ala Asp Glu Gly Pro Ala
         195                 200                 205            
 Glu Pro Glu Glu Pro Ala Asp Trp Gln Thr Tyr Arg Glu Asp Glu His
     210                 215                 220                
 Phe Ile Cys Ile Arg Phe Glu Ala Leu Thr Glu Ala Ala Arg Arg Asn
 225                 230                 235                 240
 Val Lys Glu Ala Pro Val Phe Leu Thr Glu Leu Gln Asn Gln Glu Val
                 245                 250                 255    
 Gln Asp Gly Tyr Pro Val Ser Phe Asp Cys Val Val Thr Gly Gln Pro
             260                 265                 270        
 Met Pro Ser Val Arg Trp Phe Lys Asp Gly Lys Leu Leu Glu Glu Asp
         275                 280                 285            
 Asp His Tyr Met Ile Asn Glu Asp Gln Gln Gly Gly His Gln Leu Ile
     290                 295                 300                
 Ile Thr Ala Val Val Pro Ala Asp Met Gly Val Tyr Arg Cys Leu Ala
 305                 310                 315                 320
 Glu Asn Ser Met Gly Val Ser Ser Thr Lys Ala Glu Leu Arg Val Asp
                 325                 330                 335    
 Cys Glu Tyr Cys Val Trp Phe Gly Val Ser Arg Arg Gly Ala Arg Leu
             340                 345                 350        
 Arg Gly Asn Arg Glu Lys Arg Arg Ala Leu Leu Tyr Lys Arg His Asn
         355                 360                 365            
 Leu Ala Gln Ala Leu Val Ala Pro Ile Leu Leu Ser Val Val Met Asn
     370                 375                 380                
 Leu Thr Ser Phe Asp Thr Ser Pro Ala Ile Asn Thr Glu Glu Asp Ser
 385                 390                 395                 400
 Val Ala Lys Pro Val Arg Phe Leu Pro Thr Thr Lys Gln Gln Thr Pro
                 405                 410                 415    
 Ala Gly Cys Pro Gln Ser Asn Ser Asn Thr Val Tyr Leu Glu Ile Val
             420                 425                 430        
 Asn Pro Ile Lys Gly Ser Gly Pro Gly Leu Pro Leu Leu Leu Tyr Thr
         435                 440                 445            
 Pro Trp Leu Thr Leu Val Phe Pro Gln Val Ala Leu Val Ser Trp His
     450                 455                 460                
 Ala Pro Ser Leu Gly Lys Lys Gln Asn Pro Pro Met Asp Asn Ser Arg
 465                 470                 475                 480
 Met Asn Val Leu Pro Asn Ala Arg Gly Ala Phe Ser Gly Leu Ala Ile
                 485                 490                 495    
 His
    



      <210> 1726
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1726
 Met Leu Asn Thr Gly Asn Thr Leu Leu Leu Val Phe Arg Thr Val Arg
   1               5                  10                  15    
 Asp Asn Tyr Cys Ile Leu His Phe Ala Asp Glu Glu Thr Arg Thr Asn
              20                  25                  30        
 Arg Lys Met Lys Leu Leu Lys Asn Ser Ile Ser Glu Leu Lys Ile Ile
          35                  40                  45            
 Lys Lys Ser Gly Leu Asn Thr Tyr Leu Thr Leu Glu Phe Ser Leu Gln
      50                  55                  60                
 Tyr Pro
  65    



      <210> 1727
      <211> 267
      <212> PRT
      <213> Homo sapiens


      <400> 1727
 Met Val Cys Ser Pro Ala Leu Thr Cys Leu Pro Ala Thr Leu Met His
   1               5                  10                  15    
 Trp Gly Pro Pro Ala Ile Gly Gly Pro Leu Leu Leu Thr Lys Ser Ser
              20                  25                  30        
 Ala Ser Val Ile Ser Ile Ala Ala Gly Asp Ser Met Ser Phe Ser Leu
          35                  40                  45            
 Leu Gly Leu Leu Leu Val Ser Pro Phe Val Ser Lys Val Lys Gly Leu
      50                  55                  60                
 Arg Leu Gln Arg Asp Asp Phe Glu Ile Leu Lys Val Ile Gly Arg Gly
  65                  70                  75                  80
 Ala Phe Gly Glu Val Thr Met Val Arg Gln Arg Asp Thr Gly Gln Ile
                  85                  90                  95    
 Phe Ala Met Lys Met Leu His Lys Trp Glu Met Leu Lys Arg Ala Glu
             100                 105                 110        
 Thr Ala Cys Phe Arg Glu Glu Arg Asp Val Leu Val Lys Gly Asp Ser
         115                 120                 125            
 Arg Trp Val Thr Thr Leu His Tyr Ala Phe Gln Asp Glu Glu Tyr Leu
     130                 135                 140                
 Tyr Leu Val Met Asp Tyr Tyr Ala Gly Gly Asp Leu Leu Thr Leu Leu
 145                 150                 155                 160
 Ser Arg Phe Glu Asp Arg Leu Pro Pro Glu Leu Ala Gln Phe Tyr Leu
                 165                 170                 175    
 Ala Glu Met Val Leu Ala Ile His Ser Leu His Gln Leu Gly Tyr Val
             180                 185                 190        
 His Arg Asp Val Lys Pro Asp Asn Val Leu Leu Asp Val Asn Gly His
         195                 200                 205            
 Ile Arg Leu Ala Asp Phe Gly Ser Cys Leu Arg Leu Asn Thr Asn Gly
     210                 215                 220                
 Met Val Asp Ser Ser Val Ala Val Gly Thr Pro Asp Tyr Ile Ser Pro
 225                 230                 235                 240
 Glu Ile Leu Gln Ala Met Glu Glu Gly Lys Gly His Tyr Gly Pro Gln
                 245                 250                 255    
 Cys Asp Trp Trp Ser Leu Gly Gly Leu Arg Leu
             260                 265        



      <210> 1728
      <211> 372
      <212> PRT
      <213> Homo sapiens


      <400> 1728
 Met Ala Val Arg Ser Arg Arg Pro Trp Met Ser Val Ala Leu Gly Leu
   1               5                  10                  15    
 Val Leu Gly Phe Thr Ala Ala Ser Trp Leu Ile Ala Pro Arg Val Ala
              20                  25                  30        
 Glu Leu Ser Glu Arg Lys Arg Arg Gly Ser Ser Leu Cys Ser Tyr Tyr
          35                  40                  45            
 Gly Arg Ser Ala Ala Gly Pro Arg Ala Gly Ala Gln Gln Pro Leu Pro
      50                  55                  60                
 Gln Pro Gln Ser Arg Pro Arg Gln Glu Gln Ser Pro Pro Pro Ala Arg
  65                  70                  75                  80
 Gln Asp Leu Gln Gly Pro Pro Leu Pro Glu Ala Ala Pro Gly Ile Thr
                  85                  90                  95    
 Ser Phe Arg Ser Ser Pro Trp Gln Gln Pro Pro Pro Leu Gln Gln Arg
             100                 105                 110        
 Arg Arg Gly Arg Glu Pro Glu Gly Ala Thr Gly Leu Pro Gly Ala Pro
         115                 120                 125            
 Ala Ala Glu Gly Glu Pro Glu Glu Glu Asp Gly Gly Ala Ala Gly Gln
     130                 135                 140                
 Arg Arg Asp Gly Arg Pro Gly Ser Ser His Asn Gly Ser Gly Asp Gly
 145                 150                 155                 160
 Gly Ala Ala Ala Pro Ser Ala Arg Pro Arg Asp Phe Leu Tyr Val Gly
                 165                 170                 175    
 Val Met Thr Ala Gln Lys Tyr Leu Gly Ser Arg Ala Leu Ala Ala Gln
             180                 185                 190        
 Arg Thr Trp Ala Arg Phe Ile Pro Gly Arg Val Glu Phe Phe Ser Ser
         195                 200                 205            
 Gln Gln Pro Pro Asn Ala Gly Gln Pro Pro Pro Pro Leu Pro Val Ile
     210                 215                 220                
 Ala Leu Pro Gly Val Asp Asp Ser Tyr Pro Pro Gln Lys Lys Ser Phe
 225                 230                 235                 240
 Met Met Ile Lys Tyr Met His Asp His Tyr Leu Asp Lys Tyr Glu Trp
                 245                 250                 255    
 Phe Met Arg Ala Asp Asp Asp Val Tyr Ile Lys Gly Asp Lys Leu Glu
             260                 265                 270        
 Glu Phe Leu Arg Ser Leu Asn Ser Ser Lys Pro Leu Tyr Leu Gly Gln
         275                 280                 285            
 Thr Gly Leu Gly Asn Ile Glu Glu Leu Gly Lys Leu Gly Leu Glu Pro
     290                 295                 300                
 Gly Glu Asn Phe Cys Met Gly Gly Pro Gly Met Ile Phe Ser Arg Glu
 305                 310                 315                 320
 Val Leu Arg Arg Met Val Pro His Ile Gly Glu Cys Leu Arg Glu Met
                 325                 330                 335    
 Tyr Thr Thr His Glu Asp Val Glu Val Gly Arg Cys Val Arg Arg Phe
             340                 345                 350        
 Gly Gly Thr Gln Cys Val Trp Ser Tyr Glu Glu Pro Ile Phe Pro Leu
         355                 360                 365            
 Lys Thr Phe Asn
     370        



      <210> 1729
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1729
 Met Ala Lys Val Ser Val Ser Val Leu Leu Ile Ala Gly Ala Gly Val
   1               5                  10                  15    
 Val Ala His Val Arg Gly Arg Leu Cys Pro Gly Glu Leu Leu Arg Thr
              20                  25                  30        
 His Ser Gln Thr Gly Leu Lys Gln Phe Thr Leu Leu Gln Ser Leu Val
          35                  40                  45            
 Met Arg Arg Ala Thr Pro Gln His Phe Thr Gly Asp Tyr Cys Glu His
      50                  55                  60                
 Trp Arg Pro Pro His Pro Val Gly Ser Leu Ser Ala Ala Ala Tyr Leu
  65                  70                  75                  80
 Leu Pro Pro Asp Phe Gly Glu Phe Ile Gln Leu Leu Lys Thr Gly Met
                  85                  90                  95    
 Ala Cys Pro Leu Thr Ser Thr Gln Tyr Arg His Lys Val Pro Ile Lys
             100                 105                 110        
 Leu Ala Ser Arg Lys Thr Trp Lys Glu Gly Glu Glu Thr Ser Gly Leu
         115                 120                 125            
 Thr Ser Arg
     130    



      <210> 1730
      <211> 92
      <212> PRT
      <213> Homo sapiens


      <400> 1730
 Met Ser Gly Asp Leu Lys Met Val Thr Arg Leu Pro Leu Tyr Leu Phe
   1               5                  10                  15    
 Ile Gly Tyr Leu Pro Asp Ile Thr Leu Lys Ala Phe Asn Lys Ile Phe
              20                  25                  30        
 Ser Ser Leu Phe Leu Met Cys Leu Ser Asp Thr Val Leu Leu Trp Thr
          35                  40                  45            
 Thr Gln Pro Ala Leu Asp Ser Val Gly Ala Gln Thr Leu Val Asp Ser
      50                  55                  60                
 Phe Leu Pro Leu Pro Trp His Gln Ala Gln Asn Leu Ser Gln Asn Arg
  65                  70                  75                  80
 Tyr Ala Lys Glu Phe Asn Glu Phe His Gly Asn Phe
                  85                  90        



      <210> 1731
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 1731
 Met Arg Asn Leu Val Ser Gly Ser Leu Gly Met Phe Val Ala Leu Trp
   1               5                  10                  15    
 Leu Lys Trp Leu Lys Pro Ala Leu Ser Leu Ser Pro Ser Ser Trp Gly
              20                  25                  30        
 His Thr Ser Leu Gln Lys Arg Met Trp Gln Phe Pro Pro Gln Gln Gln
          35                  40                  45            
 Pro Ala Gly Ala Ser Ser Asp Ser Pro Leu Glu Glu Val Ser Ser Ser
      50                  55                  60                
 Leu His Ser Arg Cys Leu Pro Pro Ala Ala Ala Leu Val Asp Asp Cys
  65                  70                  75                  80
 Arg Asn Thr Gly Tyr Leu Pro Gln Val Ser Leu Gln Ile His Gln Pro
                  85                  90                  95    
 Phe Thr Cys Asp Lys Leu Ser Gln Glu Val Ala Pro Lys
             100                 105                



      <210> 1732
      <211> 443
      <212> PRT
      <213> Homo sapiens


      <400> 1732
 Met Cys His Arg Ala Thr Val Lys Ser Arg Phe Ala Leu Val Cys His
   1               5                  10                  15    
 Ala Trp Ile Ala Asn Ser Lys Arg Met Asn Val Cys Cys Leu Leu Thr
              20                  25                  30        
 Leu Phe Leu Ile Cys Pro Leu Leu Ser Arg Arg Pro Val Ile Leu Ser
          35                  40                  45            
 Pro Thr Met Glu Glu Gly His Gly Leu Asp Leu Thr Tyr Ile Thr Glu
      50                  55                  60                
 Arg Ile Ile Ala Val Ser Phe Pro Ala Gly Cys Ser Glu Glu Ser Tyr
  65                  70                  75                  80
 Leu His Asn Leu Gln Glu Val Thr Arg Met Leu Lys Ser Lys His Gly
                  85                  90                  95    
 Asp Asn Tyr Leu Ile Met Asp Val Gly Trp Pro Glu Leu His Ala Pro
             100                 105                 110        
 Pro Leu Asp Lys Met Cys Thr Ile Cys Lys Ala Gln Glu Ser Trp Leu
         115                 120                 125            
 Asn Ser Asn Leu Gln His Val Val Val Ile His Cys Arg His Gln Gly
     130                 135                 140                
 Val Lys Phe Asp Phe Leu Asn Val Phe Ser Gly Asn Gln Leu Arg Ser
 145                 150                 155                 160
 Trp Cys Leu Pro Gly Arg Lys Pro Thr Pro Asn Ala Asp Gln Ala Leu
                 165                 170                 175    
 Asp Arg Phe Ala Met Lys Lys Phe Tyr Asp Asp Lys Val Ser Ala Leu
             180                 185                 190        
 Met Gln Pro Ser Gln Lys Arg Tyr Val Gln Phe Leu Ser Gly Leu Leu
         195                 200                 205            
 Ser Gly Ser Val Lys Met Asn Ala Ser Pro Leu Phe Leu His Phe Val
     210                 215                 220                
 Ile Leu His Gly Thr Pro Asn Phe Asp Thr Gly Gly Val Cys Arg Pro
 225                 230                 235                 240
 Phe Leu Lys Leu Tyr Gln Ala Met Gln Pro Val Tyr Thr Ser Gly Ile
                 245                 250                 255    
 Tyr Asn Val Gly Pro Glu Asn Pro Ser Arg Ile Cys Ile Val Ile Glu
             260                 265                 270        
 Pro Ala Gln Leu Leu Lys Gly Asp Val Met Val Lys Cys Tyr His Lys
         275                 280                 285            
 Lys Tyr Arg Ser Ala Thr Arg Asp Val Ile Phe Arg Leu Gln Phe His
     290                 295                 300                
 Thr Gly Ala Val Gln Gly Tyr Gly Leu Val Phe Gly Lys Glu Asp Leu
 305                 310                 315                 320
 Asp Asn Ala Ser Lys Asp Asp Arg Phe Pro Asp Tyr Gly Lys Val Glu
                 325                 330                 335    
 Leu Val Phe Ser Ala Thr Pro Glu Lys Ile Gln Gly Ser Glu His Leu
             340                 345                 350        
 Tyr Asn Asp His Gly Val Ile Val Asp Tyr Asn Thr Thr Asp Pro Leu
         355                 360                 365            
 Ile Arg Trp Asp Ser Tyr Glu Asn Leu Ser Ala Asp Gly Glu Gly Leu
     370                 375                 380                
 Val Gly Trp Asn Phe Asn Ser Arg Asn Cys Cys Asn Pro Asn Thr Pro
 385                 390                 395                 400
 Arg Pro Glu Val Glu Thr His Arg Trp Asn Val Asp Ala Ser Met Ile
                 405                 410                 415    
 Ser Glu Ala His Glu His Pro Gln Gly Gly Gly Val Thr Gly Glu Asp
             420                 425                 430        
 Ser Glu Arg Ala Gln Asp Trp Tyr Pro Asp Ala
         435                 440            



      <210> 1733
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 1733
 Met Gly Ser Pro Gly Cys Trp Leu Leu Pro Leu Ser Leu Cys Ala Glu
   1               5                  10                  15    
 Leu Pro Val Cys Gly Pro Ser Ile Gln Leu Ala Ala Trp Thr Lys Trp
              20                  25                  30        
 Gly Pro Gly Ala Val Gly Ala Leu Ile Ala Gly Gly Ala Gln Leu Gly
          35                  40                  45            
 Pro Gln Leu Gly Gln Arg Val Gln Gly Met Ala Pro Gln Val Gly Ser
      50                  55                  60                
 Gly Gly Val Arg Trp Arg Ser Gly Arg Pro Leu Trp Leu Ser Phe Glu
  65                  70                  75                  80
 Gly Ile Gln Val Asp Gly Arg
                  85        



      <210> 1734
      <211> 343
      <212> PRT
      <213> Homo sapiens


      <400> 1734
 Met Trp Pro Leu Thr Ala Leu Leu Leu Leu Val Pro Ser Ser Gly Gln
   1               5                  10                  15    
 Ala Ala Thr Leu Glu Lys Pro Ile Leu Ser Leu His Pro Pro Trp Thr
              20                  25                  30        
 Thr Ile Phe Lys Gly Glu Arg Val Thr Leu Lys Cys Asp Gly Tyr His
          35                  40                  45            
 Pro Leu Leu Leu Glu Leu Gln Pro Ile Ser Thr Leu Trp Tyr Leu Gly
      50                  55                  60                
 His Leu Leu Leu Pro Ser His Lys Lys Ser Ile Glu Val Gln Thr Pro
  65                  70                  75                  80
 Gly Val Tyr Arg Cys Gln Thr Arg Gly Ala Pro Val Ser Asp Pro Ile
                  85                  90                  95    
 His Leu Ser Val Ser Asn Asp Trp Leu Ile Leu Gln Val Pro Tyr Ala
             100                 105                 110        
 Pro Val Phe Glu Gly Glu Pro Leu Val Leu Arg Cys Arg Gly Trp Tyr
         115                 120                 125            
 Asp Lys Val Val Tyr Lys Leu His Tyr Tyr His Asp Gly Gln Ala Val
     130                 135                 140                
 Arg Tyr Phe His Ser Ser Ala Asn Tyr Thr Val Leu Gln Ala Arg Ala
 145                 150                 155                 160
 Ser Asp Ser Gly Arg Tyr Gln Cys Ser Gly Thr Met Arg Ile Pro Val
                 165                 170                 175    
 Glu Ser Ala Pro Met Phe Ser Ala Lys Val Ala Val Thr Val Gln Glu
             180                 185                 190        
 Leu Phe Arg Ala Pro Val Leu Arg Val Met Gly Pro Arg Glu Ala Arg
         195                 200                 205            
 Gly Ala Ala Leu Gly Gly Val Val Leu Arg Cys Asp Thr Arg Leu His
     210                 215                 220                
 Pro Gln Lys Arg Asp Thr Pro Leu Gln Phe Ala Phe Tyr Lys Tyr Ser
 225                 230                 235                 240
 Arg Ala Val Arg Arg Phe Asp Trp Gly Ala Glu Tyr Thr Val Pro Glu
                 245                 250                 255    
 Pro Glu Val Glu Glu Leu Glu Ser Tyr Trp Cys Glu Ala Ala Thr Ala
             260                 265                 270        
 Thr Arg Ser Val Arg Lys Arg Ser Pro Trp Leu Gln Leu Pro Gly Pro
         275                 280                 285            
 Gly Glu Cys Leu His Thr Leu Pro Asp Ala Asp Pro Gly Gly Gln Pro
     290                 295                 300                
 Cys Phe Arg Leu Ser Ala Pro Thr Asn His Pro Arg Glu Leu Glu Glu
 305                 310                 315                 320
 Asn Ala Cys Gly Tyr Lys Leu Leu Cys Glu Val Glu Ile Val Ser His
                 325                 330                 335    
 Tyr Thr Ser Trp Ala Leu Leu
             340            



      <210> 1735
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1735
 Met Ala Met Val Val Leu Gly Leu Ser Pro Ile Pro Trp Gln Ala Leu
   1               5                  10                  15    
 Val Ser Cys Pro Leu Arg Cys Leu Phe Leu Ser Glu Gln Asp Pro Val
              20                  25                  30        
 Gln Gly Thr Thr Leu His Val Val Thr Pro Ala Gln His Pro Leu Pro
          35                  40                  45            
 Gly Asp Ser Ser Arg Leu Ser Leu Phe His Thr Gln Phe Gly Gly Leu
      50                  55                  60                
 His Val Thr Arg Asp Leu His Ser Ser Gln Lys Glu Ser His Ala Ala
  65                  70                  75                  80
 Ala Ala Cys Val Trp Arg His Phe Pro Gly Leu Tyr Ile Thr Ala Arg
                  85                  90                  95    
 Arg Asp Ser Gln Ala Asp Asp Ser Val Ala Lys Val Thr Asn Glu Leu
             100                 105                 110        
 Gly Glu Asn Glu Asn Leu Gly Thr Val Glu Gln Met Glu Asn Ala Arg
         115                 120                 125            
 Val Ser Ala Cys Gly Arg Leu Leu
     130                 135    



      <210> 1736
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1736
 Met Thr Ser Leu Arg Pro Ala Ile Ser Ala Leu Leu Ala Gly Cys Ala
   1               5                  10                  15    
 Ser Leu Ala Val Ala Glu Arg Glu Val Ala Leu Trp Leu Trp Thr Gly
              20                  25                  30        
 Ile Val Phe Val Gln Trp Thr Lys Ala Glu Asn Pro Glu Ala Asp Cys
          35                  40                  45            
 Pro Val Ala Ala Ala Pro Gln Asp Pro Glu Gly Ser Gln Ser Gln Pro
      50                  55                  60                
 Glu Thr Thr His Gly Cys Cys Gly Pro Leu Asp His Gly Gly Met Glu
  65                  70                  75                  80
 Met Gly Cys Ala Leu Ser Arg Asp Ser Gly Leu Gln His Val Trp Ala
                  85                  90                  95    
 Ala Ala Trp Lys Leu Ala Ser Leu Gly Ala Leu Gly Asp Ser Pro
             100                 105                 110    



      <210> 1737
      <211> 304
      <212> PRT
      <213> Homo sapiens


      <400> 1737
 Met Phe Ser Val Leu Ser Tyr Gly Arg Leu Val Ala Arg Ala Val Leu
   1               5                  10                  15    
 Gly Gly Leu Ser Gln Thr Asp Pro Arg Ala Gly Gly Gly Gly Gly Gly
              20                  25                  30        
 Asp Tyr Gly Leu Val Thr Ala Gly Cys Gly Phe Gly Lys Asp Phe Arg
          35                  40                  45            
 Lys Gly Leu Leu Lys Lys Gly Ala Cys Tyr Gly Asp Asp Ala Cys Phe
      50                  55                  60                
 Val Ala Arg His Arg Ser Ala Asp Val Leu Gly Val Ala Asp Gly Val
  65                  70                  75                  80
 Gly Gly Trp Arg Asp Tyr Gly Val Asp Pro Ser Gln Phe Ser Gly Thr
                  85                  90                  95    
 Leu Met Arg Thr Cys Glu Arg Leu Val Lys Glu Gly Arg Phe Val Pro
             100                 105                 110        
 Ser Asn Pro Ile Gly Ile Leu Thr Thr Ser Tyr Cys Glu Leu Leu Gln
         115                 120                 125            
 Asn Lys Val Pro Leu Leu Gly Ser Ser Thr Ala Cys Ile Val Val Leu
     130                 135                 140                
 Asp Arg Thr Ser His Arg Leu His Thr Ala Asn Leu Gly Asp Ser Gly
 145                 150                 155                 160
 Phe Leu Val Val Arg Gly Gly Glu Val Val His Arg Ser Asp Glu Gln
                 165                 170                 175    
 Gln His Tyr Phe Asn Thr Pro Phe Gln Leu Ser Ile Ala Pro Pro Glu
             180                 185                 190        
 Ala Glu Gly Val Val Leu Ser Asp Ser Pro Asp Ala Ala Asp Ser Thr
         195                 200                 205            
 Ser Phe Asp Val Gln Leu Gly Asp Ile Ile Leu Thr Ala Thr Asp Gly
     210                 215                 220                
 Leu Phe Asp Asn Met Pro Asp Tyr Met Ile Leu Gln Glu Leu Lys Lys
 225                 230                 235                 240
 Leu Lys Asn Ser Asn Tyr Glu Ser Ile Gln Gln Thr Ala Arg Ser Ile
                 245                 250                 255    
 Ala Glu Gln Ala His Glu Leu Ala Tyr Asp Pro Asn Tyr Met Ser Pro
             260                 265                 270        
 Phe Ala Gln Phe Ala Cys Asp Asn Gly Leu Asn Val Arg Gly Gly Lys
         275                 280                 285            
 Pro Asp Asp Ile Thr Val Leu Leu Ser Ile Val Ala Glu Tyr Thr Asp
     290                 295                 300                





      <210> 1738
      <211> 217
      <212> PRT
      <213> Homo sapiens


      <400> 1738
 Met Thr Gly Val Gly Trp Ser Leu Val Phe Leu Phe Ser Pro Val Glu
   1               5                  10                  15    
 Ser Leu Lys Lys Leu Glu Leu Tyr Phe Leu Leu Thr Pro Glu Asn Glu
              20                  25                  30        
 Ala Val Gly Lys Ser Trp Ile Val Lys Arg Ser Tyr Glu Asp Phe Arg
          35                  40                  45            
 Val Leu Asp Lys His Leu His Leu Cys Ile Tyr Asp Arg Arg Phe Ser
      50                  55                  60                
 Gln Leu Ser Glu Leu Pro Arg Ser Asp Thr Leu Lys Asp Ser Pro Glu
  65                  70                  75                  80
 Ile Asp Asn Lys Gly Asn His Leu Leu Val His Glu Glu Ser Ser Ile
                  85                  90                  95    
 Asn Thr Pro Ala Val Gly Ala Ala His Val Ile Lys Arg Tyr Thr Ala
             100                 105                 110        
 Arg Ala Pro Asp Glu Leu Thr Leu Glu Val Gly Asp Ile Val Ser Val
         115                 120                 125            
 Ile Asp Met Pro Pro Lys Val Leu Ser Thr Trp Trp Arg Gly Lys His
     130                 135                 140                
 Gly Phe Gln Val Gly Leu Phe Pro Gly His Cys Val Glu Leu Ile Asn
 145                 150                 155                 160
 Gln Lys Val Pro Gln Ser Val Thr Asn Ser Val Pro Lys Pro Gly Phe
                 165                 170                 175    
 Lys Ala Gln Gly Gln His Ala Ala Glu Asp Phe Gly Met Val His Asp
             180                 185                 190        
 Glu Ser Ser Leu Asp Ile Ser Ser Leu Ala Ser Tyr Cys Tyr Gly Thr
         195                 200                 205            
 Leu Ala Asn Cys Phe Ile Ser Leu Pro
     210                 215        



      <210> 1739
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1739
 Met Gln Leu Ala Arg Ser Ser Leu Gly Leu Phe Leu Ile Asn Cys Ser
   1               5                  10                  15    
 Val Ser Lys Thr Thr Leu Pro Val Leu Thr Leu Phe Thr Lys Asp Pro
              20                  25                  30        
 Arg Pro Leu Cys Gly Glu Ala Lys Glu Val Leu Lys Pro Tyr Ser Asn
          35                  40                  45            
 Arg Phe Ile Leu Gln Glu Val Asn Val Thr Leu Pro Glu Asn Ser Ala
      50                  55                  60                
 Trp Tyr Glu Arg Tyr Lys Phe Asp Ile Pro Val Phe His Leu Cys Gly
  65                  70                  75                  80
 Gln Phe Leu Met Met His Gln Glu Asn Thr Ser Lys Leu Asp Lys Gln
                  85                  90                  95    
 Leu Leu Lys Leu Glu Gln Gln Ser Thr Gly Gly
             100                 105        



      <210> 1740
      <211> 326
      <212> PRT
      <213> Homo sapiens


      <400> 1740
 Met Pro Ser Gly Pro Ile Gly Phe Trp Arg Gln His Ile Ser His Leu
   1               5                  10                  15    
 Gly Met Leu Leu Trp Ser Thr Tyr Gln Val Thr Gln Lys Ala Thr Ser
              20                  25                  30        
 Phe Glu Trp Gly Pro Glu Gln Lys Asn Ala Leu Gln Gln Val Gln Ala
          35                  40                  45            
 Ala Val Gln Ala Ser Leu Pro Phe Gly Pro Tyr Asp Pro Ala Asp Pro
      50                  55                  60                
 Met Arg Gln Pro Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Glu His
  65                  70                  75                  80
 Leu Thr Met Gly His Gln Val Thr Met Gln Pro Glu Leu Pro Ile Met
                  85                  90                  95    
 Asn Trp Leu Leu Ser Asp Pro Ser Ser Arg Lys Pro Ala Leu Thr Ala
             100                 105                 110        
 Ser Trp Gly Val Leu Tyr Asp Gln Leu Ile Glu Glu Glu Asn Thr Arg
         115                 120                 125            
 Asp Trp Phe Thr Gly Gly Ser Ala Pro Tyr Ala Gly Thr Thr Pro Lys
     130                 135                 140                
 Trp Thr Ala Val Ala Leu Gln Pro Arg Ser Arg Thr Ser Leu Lys Asp
 145                 150                 155                 160
 Ser Ser Glu Gly Lys Ser Ser Gln Trp Ala Glu Leu Arg Ala Val His
                 165                 170                 175    
 Leu Val Ala His Phe Val Trp Lys Glu Lys Trp Ser Asp Val Arg Leu
             180                 185                 190        
 Tyr Thr Asp Ser Trp Ala Val Ala Asn Gly Leu Ala Gly Trp Ser Gly
         195                 200                 205            
 Ser Trp Lys Lys His Asp Trp Lys Ile Gly Asp Lys Glu Ile Trp Gly
     210                 215                 220                
 Arg Gly Met Trp Met Asp Leu Ser Glu Trp Ser Lys Thr Gly Lys Ile
 225                 230                 235                 240
 Phe Val Ser His Val Ser Ala His Gln Arg Val Thr Ser Ala Glu Glu
                 245                 250                 255    
 Asp Phe Asn Asn Gln Val Asp Lys Met Thr Cys Ala Val Asp Thr Thr
             260                 265                 270        
 Gln Leu Leu Ser Pro Ala Thr Pro Ala Ile Val Gln Trp Ala His Glu
         275                 280                 285            
 Gln Ser Gly His Gly Gly Arg Asp Gly Gly Tyr Thr Trp Ala Gln Gln
     290                 295                 300                
 Gln Gly Leu Pro Leu Thr Lys Ala Asp Leu Ala Met Ala Thr Ala Glu
 305                 310                 315                 320
 Cys Pro Ile Cys Gln Gln
                 325    



      <210> 1741
      <211> 491
      <212> PRT
      <213> Homo sapiens


      <400> 1741
 Met Ala Ala Leu Leu Pro Pro Leu Thr Asp Gly Trp Thr Trp Leu Cys
   1               5                  10                  15    
 Cys Leu Gly Arg Gly Pro Glu Ser Gly Asp Thr Trp Val Ala Val Leu
              20                  25                  30        
 His Thr Gln Gly Pro Val Asp Gly Ser Leu Tyr Ala Lys Val Arg Lys
          35                  40                  45            
 Lys Ser Ser Ser Asp Pro Gly Ile Pro Gly Gly Pro Gln Ala Ile Pro
      50                  55                  60                
 Ala Thr Asn Ser Pro Asp His Ser Asp His Thr Leu Ser Val Ser Ser
  65                  70                  75                  80
 Asp Ser Gly His Ser Thr Ala Ser Ala Arg Thr Asp Lys Thr Glu Glu
                  85                  90                  95    
 Arg Leu Ala Pro Gly Thr Arg Arg Gly Leu Ser Ala Gln Glu Lys Ala
             100                 105                 110        
 Glu Leu Asp Gln Leu Leu Ser Gly Phe Gly Leu Glu Asp Pro Gly Ser
         115                 120                 125            
 Ser Leu Lys Glu Met Thr Asp Ala Arg Ser Lys Tyr Ser Gly Thr Arg
     130                 135                 140                
 His Val Val Pro Ala Gln Val His Val Asn Gly Asp Ala Ala Leu Lys
 145                 150                 155                 160
 Asp Arg Glu Thr Asp Ile Leu Asp Asp Glu Met Pro His His Asp Leu
                 165                 170                 175    
 His Ser Val Asp Ser Leu Gly Thr Leu Ser Ser Ser Glu Gly Pro Gln
             180                 185                 190        
 Ser Ala Thr Trp Ser Ser Gln Asn Ser Leu Leu Ser Asp Gly Phe Gly
         195                 200                 205            
 Ser Asn Val Gly Glu Asp Pro Gln Gly Thr Leu Val Pro Asp Leu Gly
     210                 215                 220                
 Leu Gly Met Asp Gly Pro Tyr Glu Arg Glu Arg Thr Phe Gly Ser Arg
 225                 230                 235                 240
 Glu Pro Lys Gln Pro Gln Pro Leu Leu Arg Lys Pro Ser Val Ser Ala
                 245                 250                 255    
 Gln Met Gln Ala Tyr Gly Gln Ser Ser Tyr Ser Thr Gln Thr Trp Val
             260                 265                 270        
 Arg Gln Gln Gln Met Val Val Ala His Gln Tyr Ser Phe Ala Pro Asp
         275                 280                 285            
 Gly Glu Ala Arg Leu Val Ser Arg Cys Pro Ala Asp Asn Pro Gly Leu
     290                 295                 300                
 Val Gln Ala Gln Pro Arg Val Pro Leu Thr Pro Thr Arg Gly Thr Ser
 305                 310                 315                 320
 Ser Arg Val Ala Val Gln Arg Gly Val Gly Ser Gly Pro His Pro Pro
                 325                 330                 335    
 Asp Thr Gln Gln Pro Ser Pro Ser Lys Ala Phe Lys Pro Arg Phe Pro
             340                 345                 350        
 Gly Asp Gln Val Val Asn Gly Ala Gly Pro Glu Leu Ser Thr Gly Pro
         355                 360                 365            
 Ser Pro Gly Ser Pro Thr Leu Asp Ile Asp Gln Ser Ile Glu Gln Leu
     370                 375                 380                
 Asn Arg Leu Ile Leu Glu Leu Asp Pro Thr Phe Glu Pro Ile Pro Thr
 385                 390                 395                 400
 His Met Asn Ala Leu Gly Ser Gln Ala Asn Gly Ser Val Ser Pro Asp
                 405                 410                 415    
 Ser Val Gly Gly Gly Leu Arg Ala Ser Ser Arg Leu Pro Asp Thr Gly
             420                 425                 430        
 Glu Gly Pro Ser Arg Ala Thr Gly Arg Gln Gly Val Leu Ala His Val
         435                 440                 445            
 Ile Val Leu Ser Thr Pro Ala Ala Gly Thr Ser Leu Cys Leu Thr Val
     450                 455                 460                
 Val Leu Met Glu Val Ser Val Asp Tyr Val Ala Cys Pro Gly Ser His
 465                 470                 475                 480
 Gly Thr Cys Ile Val Glu Gln Lys Ser Val Pro
                 485                 490    



      <210> 1742
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1742
 Met Lys Val Val Leu Arg Gly Leu Cys Arg Ser Ile Leu Leu Ala Leu
   1               5                  10                  15    
 Pro Ser Leu Gly Thr Leu Gln Lys Phe Val Asp Asp Leu Phe Glu Thr
              20                  25                  30        
 Ile Phe Ser Thr Ala His Arg Gly Ser Ala Leu Pro Leu Ala Ile Lys
          35                  40                  45            
 Tyr Met Phe Asp Phe Leu Asp Glu Gln Ala Asp Lys His Gly Ile His
      50                  55                  60                
 Asp Pro His Val Arg His Thr Trp Lys Ser Asn Cys Arg Thr Val Pro
  65                  70                  75                  80
 Lys Arg Lys Pro Tyr Asn Gln Ser Ala Pro Lys Glu Lys Leu Ile Pro
                  85                  90                  95    
 Ser Asp Ile Ala His Ser Gln Ala Tyr Leu Ala Thr Ser Asp Ser
             100                 105                 110    



      <210> 1743
      <211> 118
      <212> PRT
      <213> Homo sapiens


      <400> 1743
 Met Leu Ala Asn Leu Ser Pro Ser Thr Phe Ile Leu Leu Ser Arg Met
   1               5                  10                  15    
 Cys Arg Gly Tyr Val His His Leu Asn Gly Pro Val Phe Cys Arg Leu
              20                  25                  30        
 Thr Phe Leu Ser Ser Ser Gly Asn Val Phe Ser Pro Leu Cys Ala Ser
          35                  40                  45            
 Ser Pro Ser Ser Ile His Lys Val Tyr Tyr Pro Glu Leu Phe Val Trp
      50                  55                  60                
 Val Ser Gln Glu Pro Phe Pro Asn Lys Asp Met Glu Gly Arg Leu Pro
  65                  70                  75                  80
 Lys Lys Ala Ser Pro Ala Val Leu Gly Leu Val Ser His Lys Asp Met
                  85                  90                  95    
 Leu Pro Gly Val Gly Thr Val Asp His Gly Ile Gln Val Phe Cys Tyr
             100                 105                 110        
 Phe Lys Phe Phe Leu Leu
         115            



      <210> 1744
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 1744
 Met Ala Arg Pro Gln Pro Ala Ala Trp Cys Ser Val Arg Ala Leu Ala
   1               5                  10                  15    
 Gly Leu Pro Gly Ala Leu Gly Ser Ser His Asn Ser Val Ser Asn Ser
              20                  25                  30        
 Leu Arg Pro Arg Cys Glu Ser Cys Gly Ala Val Phe His Ser Glu Cys
          35                  40                  45            
 Lys Glu Lys Ser Val Pro Cys Pro Arg Cys Val Arg Arg Glu Leu Gln
      50                  55                  60                
 Lys Lys Gln Lys Ser Phe Trp Gln Arg Leu Asn Met Asp Glu Ser Leu
  65                  70                  75                  80
 Glu Glu Ala Cys Thr Met Phe Glu Leu Ser Tyr Gln Asn Thr
                  85                  90                



      <210> 1745
      <211> 155
      <212> PRT
      <213> Homo sapiens


      <400> 1745
 Met Gln Leu Gly Gly Leu Ala Val Gly Leu Gly Phe Leu Gly Ser Arg
   1               5                  10                  15    
 Asp Glu Leu Leu Thr Gly Pro Ser Thr Leu Ile Pro Asp Gly Val Gln
              20                  25                  30        
 Lys Ala Pro Gly Gln Val Gly Glu Arg Leu Ala Gln Glu Ala Lys Ser
          35                  40                  45            
 Val Ser Leu Ser Ala Leu Pro Phe Asp Leu Tyr Phe Ser Tyr Tyr Asn
      50                  55                  60                
 Phe Lys Asp Thr Ile Val Leu Pro Lys Gly Ser Gln Lys Ser Asp Arg
  65                  70                  75                  80
 Val Val Ala Cys Pro Glu Ser His Asn Glu Ser Gly Leu Ser Cys Ser
                  85                  90                  95    
 His Ser Leu Gly Asp His Phe Ser Ala Phe Thr Pro Pro Phe Ile His
             100                 105                 110        
 Ala His Asn Asp Leu Leu Ser Thr His Tyr Val Ala Gly Thr Val Leu
         115                 120                 125            
 Gly Ala Arg Asp Thr Asp Asn Asp Thr Asp Lys Val Pro Ala Ile Val
     130                 135                 140                
 Ala Phe Glu Thr Gly Thr Ala Gln Val Tyr Lys
 145                 150                 155



      <210> 1746
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1746
 Met Ala Pro Asp Thr Lys Leu Leu Leu Ser Ser Arg Gly Ala Arg Cys
   1               5                  10                  15    
 Ala Thr Leu Leu Ala Leu Leu Pro Gln Ala Leu Val Gly Gln Ala Phe
              20                  25                  30        
 Gln Asp Glu Lys Val Cys Leu Pro Val Gln Gln Val Glu Ala Ser Glu
          35                  40                  45            
 His Ile Gln Gly Pro Asp Arg Val Gly Val Gln Ala Glu Gly Leu Ser
      50                  55                  60                
 Val Asp His Gly Asp Val Leu Gln Gln Ala Val Glu Gln Gly Asp Leu
  65                  70                  75                  80
 Leu Lys Val Lys Asp Glu Asp Asp Ala Ala Lys Leu Gly Ala Pro Lys
                  85                  90                  95    
 Val Arg Ile Ser Ser Ser Gly Pro Gly Pro Gln Trp His Arg Asp Val
             100                 105                 110        
 His Ser Gln Leu Glu Leu Gly Val Ser Leu
         115                 120        



      <210> 1747
      <211> 433
      <212> PRT
      <213> Homo sapiens


      <400> 1747
 Met Val Ala Pro Ala Ala Arg Val Phe Leu Arg Ala Val Arg Ala Ala
   1               5                  10                  15    
 Leu Thr Ser Thr Val Pro Asp Leu Leu Cys Leu Leu Ala Arg Gly Ser
              20                  25                  30        
 Pro Arg Gly Leu Ala Ser Gly Arg Leu Pro Leu Ala Val His Ser Ala
          35                  40                  45            
 Gln His Gly Pro Gly Ser Gly Ala Pro Trp Leu Arg Ile Ala Arg Arg
      50                  55                  60                
 Ala Leu Arg Phe Val Leu Ser Lys His Trp Gly Asp Asp Cys Tyr Leu
  65                  70                  75                  80
 Thr Asn Arg Leu Trp Gln Asp Leu Lys Pro Pro Ser His Val Glu Asn
                  85                  90                  95    
 Gly Gln Glu Leu Arg Leu Ala Pro Pro Val Gln Trp Ala Leu Gln Pro
             100                 105                 110        
 Lys Asn Leu Glu Arg Val Tyr Val Asp Thr Gln Val Ser Ala Ser Gly
         115                 120                 125            
 Asp Phe Leu Arg Gly Arg Ala Arg Gly Thr Ala Gly Pro Gly Gly Ser
     130                 135                 140                
 Gly Ser Gly Ser Pro Arg Gly Arg Gly Arg Leu Arg Arg Pro Gly Arg
 145                 150                 155                 160
 Ser Pro Gly Ala Ala Pro Ser Ser Val Ser Arg Gly Arg Lys Glu Ala
                 165                 170                 175    
 Thr Gln Ala Arg Ser Arg Ala Arg Gly Arg Arg Gly Gly Ala Val Ala
             180                 185                 190        
 Arg Val Cys Arg Pro Glu Ser Arg Gln Arg Ser His Leu Ser Pro Pro
         195                 200                 205            
 Gly Ser Gly Ala Pro Arg Gly Gln Ala Ser Ala Arg Leu Lys Thr Glu
     210                 215                 220                
 Val Arg His Ala Gly Pro Leu Val Gly Gly Ser His Pro Ala Tyr Arg
 225                 230                 235                 240
 Gly Asn Gly Ala Ser Arg Gln Leu Arg Leu Gln Pro Gly Arg Glu Arg
                 245                 250                 255    
 Ser Ala Gly Ser Leu Gln Arg Leu Glu Ser Glu Glu Lys Gly His Ser
             260                 265                 270        
 Leu Glu Met Asp Arg Ala Glu Phe Leu Lys Gly Ile Ala Val Glu Arg
         275                 280                 285            
 Asp Pro Leu Gln Asn Gln Gln Arg Pro Gly Ser Leu Ser Ser Ser Thr
     290                 295                 300                
 Gly Asp Gly Ser Lys Met Lys Cys Leu Lys Leu Arg Arg Arg Phe Thr
 305                 310                 315                 320
 Phe Ala His Thr Arg Thr Ala Gly Pro Asp Pro His Arg Asp Ala Asp
                 325                 330                 335    
 Thr Arg Ala Leu Ala Leu Pro Gly Glu Arg Arg Thr Gln Gly Leu Ser
             340                 345                 350        
 Gly Gln Tyr Ala Pro Ser Arg Asn Asn Gln Phe Cys Leu Val Leu Phe
         355                 360                 365            
 Thr Val Ala Arg Arg Ser Trp Ile Phe Ala Asn Thr Asn Leu Leu Arg
     370                 375                 380                
 Ala Pro Ala Gln Trp Glu Ala Ile Gly Ala Gly Leu Val Leu Glu Thr
 385                 390                 395                 400
 Gly Leu Met Gly Gly Val Glu Val Met Asp Ala Glu Trp Pro Pro Val
                 405                 410                 415    
 Leu Glu Val Asp Leu Met Gly Gly Val Glu Ala Met Asp Ala Lys Ser
             420                 425                 430        
 Ser
    



      <210> 1748
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 1748
 Met Asp Val Ala Thr Cys Phe Leu Asn Phe Ser Ala Ala Thr Ser Leu
   1               5                  10                  15    
 Ala Met Leu Ala Pro Ile Ser Thr Leu Met Ser Ile Pro Ile Phe Ser
              20                  25                  30        
 Arg Met Met Ser Glu Met Ser Phe Ser Pro Ser Gly Pro Ser Ser Met
          35                  40                  45            
 Pro Tyr Lys Asp Ala Lys
      50                



      <210> 1749
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1749
 Met Val Met Ala Ser Val Met Gln Lys Ile Ile Pro Arg Tyr Ser Leu
   1               5                  10                  15    
 Ala Gln Trp Leu Leu Cys Asn Gly Ser Leu Arg Trp Tyr Gln His Ser
              20                  25                  30        
 Thr Val Glu Glu Ser Arg Ile Leu Ala Gly Asn Gln Gln Lys Glu Lys
          35                  40                  45            
 Ser Lys Lys Asp Arg Lys Tyr Asn Gly His Thr Glu Ser Lys Pro Leu
      50                  55                  60                
 Thr Ile Pro Lys Asp Ile Asp Leu Arg Leu Glu Thr Lys Ser Val Thr
  65                  70                  75                  80
 Glu Val Asp Thr Leu Ala Leu His Tyr Phe Pro Glu Tyr Gln Gln Pro
                  85                  90                  95    
 Gly Tyr Ser Val Arg Pro Glu Lys Phe Met Leu Phe Phe Ser Ser Thr
             100                 105                 110        
 Leu Val His Arg Asn Ser Ser Thr Ala Gln Asp Gln Ala Thr Val Thr
         115                 120                 125            
 Ala Val Thr Leu Leu Lys Ser Leu Gly
     130                 135        



      <210> 1750
      <211> 185
      <212> PRT
      <213> Homo sapiens


      <400> 1750
 Met Thr Pro Gly Pro Ala Ser Pro Thr His Gln Pro Leu Ala Thr Gln
   1               5                  10                  15    
 Leu Leu Ile Thr Leu Tyr Met Ala Gly Ala Ala Ala Arg Trp Asp Leu
              20                  25                  30        
 Cys Ile Asp Gln Ala Val Val Phe Ile Glu Asp Ala Ile Gln Val Lys
          35                  40                  45            
 Arg Thr Glu Gly Gly Ala Ser Gly His Gly Ser Ser Ser Val Pro Gly
      50                  55                  60                
 Gly Leu Val Phe Cys Ile Leu Asp Ala Phe Ala Ala Leu Met His Arg
  65                  70                  75                  80
 Val Leu Arg Pro Val Val Asp His Pro Ile Leu Gly Gly Leu Asp Leu
                  85                  90                  95    
 Val Thr Cys Phe Tyr Leu Ile Glu Tyr Ser Lys Ser Asp Glu Met Ser
             100                 105                 110        
 Leu Pro Arg Leu Gly Trp Thr Asp Gly Asp Phe Gln Leu Val Ser Leu
         115                 120                 125            
 Leu Ser Gly Ser Ser Cys Leu Leu Ala Leu Val Lys Pro Ala Thr Ile
     130                 135                 140                
 Cys Thr Glu Gly Ala Arg Thr Tyr Val Thr Ala Thr Leu Val Leu Gly
 145                 150                 155                 160
 Val Ser Ala Ser Lys Ala Trp Thr Pro Asp His Ser Pro Ala Leu Glu
                 165                 170                 175    
 Val Asn Glu Glu Thr Ala Pro Asn Met
             180                 185



      <210> 1751
      <211> 311
      <212> PRT
      <213> Homo sapiens


      <400> 1751
 Met Ser Leu Lys Ala Met Asp Cys Phe Leu Cys Ile Leu Met Leu Ser
   1               5                  10                  15    
 Pro Arg Pro Ala Pro Gly Gln Ala Leu Trp Ala Gln Gly Gln Lys Gly
              20                  25                  30        
 Ala Arg Lys Tyr His Cys Met Arg Gln Arg Ser Gly Ala Val Thr Glu
          35                  40                  45            
 Met Val Pro Cys Ala Pro Glu Leu Thr Thr Arg Val Ser Arg Val Val
      50                  55                  60                
 Thr Ala Gly Val Glu Pro Asp Leu Val Ala Ser Gly Leu Met Leu Ser
  65                  70                  75                  80
 Leu Arg Ser Thr Met Ala Phe Pro Trp Val Val Trp Pro Lys Ile Arg
                  85                  90                  95    
 Val Cys Ile His Gln Ala Thr Ala Ile Tyr Gln Ala Leu Cys Ser Leu
             100                 105                 110        
 Trp Gly Tyr Arg Leu Glu Arg Ala Ser Pro Cys Thr Pro Leu Leu Leu
         115                 120                 125            
 Ser Ser Ile Pro Asp Arg Gln Ile Leu Pro Gly Ala Ser Ile Pro Gly
     130                 135                 140                
 Phe Ser Leu Ser Ala Pro Pro Leu Ala Trp Leu His Gln Glu Arg Leu
 145                 150                 155                 160
 Phe Pro Tyr Gly Cys Cys Gly Cys Leu Cys Phe Leu Ala Pro Phe Gln
                 165                 170                 175    
 Ala Lys Cys Ser Leu Ala Arg Lys Pro Phe Pro Gly Ala Gln Ala Phe
             180                 185                 190        
 Val Pro Ser Arg Ala Gly Thr Asn Arg Gly Cys Asp Gln Lys Phe Pro
         195                 200                 205            
 Leu Gly Thr Ile Ser Ala Thr Leu Pro Ile Ile Leu Thr Leu Pro Leu
     210                 215                 220                
 Phe Ala Ser Thr Asp His Tyr Phe Leu His Ala Gly His Ser Asp Pro
 225                 230                 235                 240
 Leu Phe Met Thr Glu Thr Phe Val Ser Ser Phe Lys Ala Leu Leu Ser
                 245                 250                 255    
 Ser Trp Cys Glu Glu Leu Gly Arg Leu Leu Leu Leu Arg His Gln Lys
             260                 265                 270        
 Ser Arg Gln Ser Asp Pro Pro Gly Lys Leu Pro Met Gln Pro Pro Leu
         275                 280                 285            
 Ser Ser Met Ser Ser Met Lys Pro Thr Leu Ser His Arg Ile Ile Leu
     290                 295                 300                
 Leu Ser Ser Ser Tyr Val Ser
 305                 310    



      <210> 1752
      <211> 158
      <212> PRT
      <213> Homo sapiens


      <400> 1752
 Met Gly Leu Trp Ala Leu Trp Gly His Leu Ala Ala Arg Ser Leu Gly
   1               5                  10                  15    
 Ala Val Gly Gly Trp Arg Glu Val Met Leu Gly Arg Asn Gly Gly Thr
              20                  25                  30        
 Arg Ala Ser Lys Ala Gln Leu Ala Arg Ala Gly Ile Val Arg Asn Ala
          35                  40                  45            
 Gly Val Ser Asp His Ala Gln Pro Arg Pro Ser Leu Met Thr Ser Glu
      50                  55                  60                
 Lys Thr Ala Ala Leu Pro Leu Thr Gln Asp Lys Leu Ala Thr Gly Asn
  65                  70                  75                  80
 Glu Val Asn Arg Arg Ala Ala Gly His Gln Ala Glu Gln Ser His Ser
                  85                  90                  95    
 Phe Thr Pro Leu Val Leu Thr Val Tyr Pro Leu Glu Ala Arg Ser Trp
             100                 105                 110        
 Gly Ala Val Ser Glu Gln Ala Gln Lys His Glu Ala Gly Ser Leu Thr
         115                 120                 125            
 Ser Gly Thr Ser Leu Gln Gly Thr Ser Ser Asn Leu Leu Thr Gln Ser
     130                 135                 140                
 Gly Tyr Gln Ala Pro Ser Arg Ser Asp Phe Ser Val Gly Leu
 145                 150                 155            



      <210> 1753
      <211> 258
      <212> PRT
      <213> Homo sapiens


      <400> 1753
 Met Thr Pro Pro Lys Leu Arg Ala Ser Leu Ser Pro Ser Leu Leu Leu
   1               5                  10                  15    
 Leu Leu Ser Gly Cys Leu Leu Ala Ala Ala Arg Arg Glu Lys Gly Ala
              20                  25                  30        
 Ala Ser Asn Val Ala Glu Pro Val Pro Gly Pro Thr Gly Cys Ser Ser
          35                  40                  45            
 Gly Arg Phe Leu Ser Pro Glu Gln His Ala Cys Ser Trp Gln Leu Leu
      50                  55                  60                
 Leu Pro Ala Pro Glu Ala Ala Ala Gly Ser Glu Leu Ala Leu Arg Cys
  65                  70                  75                  80
 Gln Ser Pro Asp Gly Ala Arg His Gln Cys Ala Tyr Arg Gly His Pro
                  85                  90                  95    
 Glu Arg Cys Ala Ala Tyr Ala Ala Arg Arg Ala His Phe Trp Lys Gln
             100                 105                 110        
 Val Leu Gly Gly Leu Arg Lys Lys Arg Arg Pro Cys His Asp Pro Ala
         115                 120                 125            
 Pro Leu Gln Ala Arg Leu Cys Ala Gly Lys Lys Gly His Gly Ala Glu
     130                 135                 140                
 Leu Arg Leu Val Pro Arg Ala Ser Pro Pro Ala Arg Pro Thr Val Ala
 145                 150                 155                 160
 Gly Phe Ala Gly Glu Ser Lys Pro Arg Ala Arg Asn Arg Gly Arg Thr
                 165                 170                 175    
 Arg Glu Arg Ala Ser Gly Pro Ala Ala Gly Thr Pro Pro Pro Gln Ser
             180                 185                 190        
 Ala Pro Pro Lys Glu Asn Pro Ser Glu Arg Lys Thr Asn Glu Gly Lys
         195                 200                 205            
 Arg Lys Ala Ala Leu Val Pro Asn Glu Glu Arg Pro Met Gly Thr Gly
     210                 215                 220                
 Pro Asp Pro Asp Gly Leu Asp Gly Asn Ala Glu Leu Thr Glu Thr Tyr
 225                 230                 235                 240
 Cys Ala Glu Lys Trp His Ser Leu Cys Asn Phe Phe Val Asn Phe Trp
                 245                 250                 255    
 Asn Gly
        



      <210> 1754
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 1754
 Met Ala Asp Trp Glu Leu Trp Leu Thr Ala Ala Met Leu Ser Ile Met
   1               5                  10                  15    
 Ile Glu Tyr Cys Ile Thr Phe Cys Glu Leu Lys Gln Lys Leu Asp Glu
              20                  25                  30        
 Glu Gly Ser Lys Cys Ser Ile Leu Ser Lys His Gln Gln Phe Val Glu
          35                  40                  45            
 His Cys Cys Met Arg Cys Cys Ser Pro Phe Thr Phe Leu Val Asn Thr
      50                  55                  60                
 Lys Arg Gln Cys Gly Asp Cys Lys Phe Asn Val Cys Lys Ser Cys Cys
  65                  70                  75                  80
 Ser Tyr Gln Lys His Glu Lys Ala Trp Val Cys Cys Val Cys Gln Gln
                  85                  90                  95    
 Ala Arg Asn Leu Ser Arg Lys Glu Ile His Glu Ile Cys Gly Ile Phe
             100                 105                 110        
 Leu His Pro Glu Met Ser Leu Arg Pro Cys Leu Thr Glu Lys Tyr Val
         115                 120                 125            
 Phe Gln Ser Thr Thr Asp Val Trp Pro Val Ser Gly Gln Ser Phe Met
     130                 135                 140                
 Leu Tyr Leu Asp His Ile Leu Val Phe
 145                 150            



      <210> 1755
      <211> 216
      <212> PRT
      <213> Homo sapiens


      <400> 1755
 Met Leu Arg His Leu Gly Ser Gln Ala Ala Val Ala Leu Cys Val Gln
   1               5                  10                  15    
 Ala Ala Ala Ala Trp Gln Pro Pro Ser Pro Leu Ala Leu Leu Ala Ser
              20                  25                  30        
 Gln Lys Gln Gly His Val Ser Gln Trp Leu Gln Pro Ser Gln Ala Phe
          35                  40                  45            
 Cys Pro Ala Ala Ala Ala Ala Gln Glu Arg Glu Leu Arg Thr His Arg
      50                  55                  60                
 Ser Thr Pro His Glu Val Thr Ala Glu Cys Pro Tyr Lys Arg Leu Arg
  65                  70                  75                  80
 Ser Pro Ser Gly Ile Met Ala Gln Val Ala Asp Ser Thr Leu Pro Met
                  85                  90                  95    
 Glu Asp Glu Glu Ser Met Glu Asp Glu Glu Ser Val Glu Asp Asp Ser
             100                 105                 110        
 Val Glu Ser Arg Met Val Val Thr Phe Leu Ile Ser Ala Leu Glu Ser
         115                 120                 125            
 Thr Phe Asp Asp Leu Thr Ala Glu Glu Glu Ala Val Ser Ser Lys Cys
     130                 135                 140                
 Val Asn Leu Ala Lys Asp Asn Gln Val Ile Gln Gln Glu Leu Leu Ser
 145                 150                 155                 160
 Met Lys Lys Val Gln Gln Glu Cys Glu Lys Leu Glu Glu Asn Gln Lys
                 165                 170                 175    
 Met Leu Glu Glu Glu Ile Leu Asn Leu Lys Thr His Met Glu Asn Ser
             180                 185                 190        
 Ile Val Glu Leu Ser Glu Leu Gln Glu Tyr Lys Ser Glu Leu Asp Glu
         195                 200                 205            
 Arg Ala Met Gln Ala Val Glu Lys
     210                 215    



      <210> 1756
      <211> 163
      <212> PRT
      <213> Homo sapiens


      <400> 1756
 Met Asp Arg Cys Pro Ser Ile Leu Pro Leu Pro Val Arg Leu Val Phe
   1               5                  10                  15    
 Gln Ile Leu Leu Thr Gly Gly Ser Cys Ala Glu Glu Thr Gln Val Gln
              20                  25                  30        
 Glu Pro Val Ser Ile Cys Glu Ser Arg Asp Gly Lys His Val Arg Gly
          35                  40                  45            
 Asp Gln Arg Ser Val Ser Leu Ala His Ser Lys Gly Glu Phe Arg Ser
      50                  55                  60                
 Val Ser Ala Val Gln Ser Pro Gly Val Ser Leu Glu Asp Gly Pro Asn
  65                  70                  75                  80
 Ser Leu Lys Lys Trp Ile Leu Lys Leu Asn Thr Asn Ile Met Asn Arg
                  85                  90                  95    
 Arg Lys Tyr Leu Gly Lys Pro Met Cys Asn Met Leu Thr Asp Val Leu
             100                 105                 110        
 Ala Leu Pro Met Leu Ser Asp Ser Thr Met Leu Ser Asp Ser Ser Gly
         115                 120                 125            
 Pro Ser His Ala Leu Ala Arg Gly Arg Ser Gly Arg Ala Met Leu Thr
     130                 135                 140                
 Gly Ala Ala Glu Ser Gln Gln Pro Phe Ser Arg Glu Gly Val Ser Ser
 145                 150                 155                 160
 Ile Trp Lys
            



      <210> 1757
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 1757
 Met Leu Trp Ile Gly Ser Val Asn Ile His Phe Thr Leu Lys Gln Tyr
   1               5                  10                  15    
 Pro Leu Ile Ser Phe Leu Ala Val Met Lys Leu Asp Met Asn Asn Leu
              20                  25                  30        
 Phe Phe Asn Val Ala Asp Val Ile Gly Ile Ala Phe Tyr His Phe Val
          35                  40                  45            
 Ser Thr Gln Phe Pro Ile Phe Asn Leu Ser Asp
      50                  55                



      <210> 1758
      <211> 491
      <212> PRT
      <213> Homo sapiens


      <400> 1758
 Met Ile Leu Leu Gln Leu Leu Gln Leu Leu Gly Arg Val Cys Gly Cys
   1               5                  10                  15    
 Leu Val Leu Trp Gln Arg Thr Pro Ala Arg Val Glu His Pro Gly His
              20                  25                  30        
 Gln Gly Ser Gln Gly His Pro Ile Asn Arg Pro Met Thr Val Ser Glu
          35                  40                  45            
 Lys Arg Ser Trp Gly Gly Val Leu Ser Ala Gly Thr Arg Pro Ala Asn
      50                  55                  60                
 Phe Val Val Glu Ser Pro Ile Ser Val Gly Ser Gly Arg Tyr Phe Phe
  65                  70                  75                  80
 Lys Arg Ala Val Asp Phe Glu Thr Gly Gly Gly Glu Ser Ser Lys Gln
                  85                  90                  95    
 Tyr Ala Phe Leu Cys Ser Glu Glu Arg Met Ser Glu Val Phe Lys Asp
             100                 105                 110        
 Glu Leu Met Asn Leu Ile Tyr Arg Thr Pro Val Thr Gln Lys Ala Leu
         115                 120                 125            
 Thr Val Glu Arg Phe Phe Pro Val Leu Leu Ser Thr Pro Glu Thr Val
     130                 135                 140                
 Leu Thr Cys Phe His Ser Leu Gln Val Ala Gly Gln Gln Ala Asp Ser
 145                 150                 155                 160
 Ser Ser Ala Ala Val Ser Ser Leu Phe Gln Thr Val Lys Ala Lys Asn
                 165                 170                 175    
 Val Ala Ala Gly Pro Arg Glu Val Ala Ile Leu Leu Arg Ile Ile Pro
             180                 185                 190        
 Trp Thr Thr Ala Ser Ser Phe Asp Phe Val Pro Phe Ser Pro Ser Leu
         195                 200                 205            
 His Leu Leu Thr Leu Ile Leu Ser Gly Glu Val Glu Gly Glu Ser Ile
     210                 215                 220                
 Pro Val Gly Glu Leu Ala Val Val Ser Gly Thr Gln Trp Gln Val Thr
 225                 230                 235                 240
 Thr Val Trp Gly Cys Gln Leu Leu Pro His Pro Ile Pro Leu Arg Ala
                 245                 250                 255    
 Ser Arg Glu Arg Glu Pro Gly Arg Ala Ala Arg Leu Ala Glu Thr Ser
             260                 265                 270        
 Leu Arg Pro Gln Gln Glu Ser Phe Tyr Ser Phe Pro Glu Thr Val Thr
         275                 280                 285            
 Ser Phe Pro Asp Arg Leu Leu Gly Ala Phe Cys Cys Arg Pro Thr Arg
     290                 295                 300                
 Gln Leu Pro Ala Ser Pro Ala Arg Phe Asp Phe Ile Leu Ala Ala Ala
 305                 310                 315                 320
 Phe Ser Leu Thr Gly Gly Leu Ser Arg Arg Asn Leu Ala Leu Leu Ser
                 325                 330                 335    
 Asn Leu Glu Leu Glu His Ser Val Thr Glu Gly Lys Gly Arg Gly Phe
             340                 345                 350        
 Gln Leu Leu Glu Leu Gly Asn Cys Ala Gly Leu Ser Gln Arg Ala Ile
         355                 360                 365            
 Cys Gly Ser Glu Gly Ala Lys Leu Gln Cys Ser Glu Gly Ala Glu Ala
     370                 375                 380                
 Pro Gly Ala Gln Glu Phe Phe Gly Cys Val Arg Ile His Gln Phe Pro
 385                 390                 395                 400
 Ala Ser Leu Arg Met Thr Gly Lys Ser Gly Glu Thr Arg Cys Pro Pro
                 405                 410                 415    
 Asn Val Gly Gly Lys Leu Glu Pro Leu Ser Gln His Leu Trp Lys Gly
             420                 425                 430        
 Phe Asn Ala Ser Trp Ala Val Lys Phe Ser Ala Trp Thr Leu His Ser
         435                 440                 445            
 Val Leu Ser Ala Pro Phe Ala Ser Val Pro Ala Leu Val Pro Asn Pro
     450                 455                 460                
 Leu Asp Glu Glu Pro Arg Cys Ala His Leu Trp Ile Pro Ser Ala Lys
 465                 470                 475                 480
 His Gly Val Gln His Leu Thr His Gly Cys Cys
                 485                 490    



      <210> 1759
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 1759
 Met Ile Leu Gly Ser Leu Ala Phe Tyr Leu Val Gln Leu Thr Gly Ser
   1               5                  10                  15    
 Glu Thr Gly Gln Ala Ser Arg Leu Arg Ser Ser Pro Gln Ala Arg Gln
              20                  25                  30        
 Ser Gly Lys Asp Glu Thr His Ser Asp Pro Thr Gly Arg Glu Ala Cys
          35                  40                  45            
 Glu Ala Asp Ser Thr Trp Ala His Pro Asp Gln Val Thr Gly Arg Gly
      50                  55                  60                
 Leu Gly Glu Ser Gly His Pro Ser Gly Leu Gln Leu Pro Glu Val Glu
  65                  70                  75                  80
 Gly Asp Gln Ala Val Pro Thr Thr Phe Arg Thr Ser Ala Gly Gln Gly
                  85                  90                  95    
 Ser Ala Pro Ala Pro Arg Thr Leu Gly Pro Leu Ser Gln Ala Arg Glu
             100                 105                 110        
 Lys Gln Glu Cys Lys Thr Trp Val Leu Pro Gly Ala Ser Phe Thr Trp
         115                 120                 125            
 His Arg Lys Ala Leu Glu Arg Ser Glu Glu Lys Thr Thr Asn Leu Leu
     130                 135                 140                
 Gly Gln Lys Lys
 145            



      <210> 1760
      <211> 195
      <212> PRT
      <213> Homo sapiens


      <400> 1760
 Met Arg Val Lys Arg Leu Leu Lys Ala Gly Val Ile Ser Ala Leu Ala
   1               5                  10                  15    
 Cys Met Val Lys Ala Asp Ser Ala Ile Leu Thr Asp Gln Thr Lys Glu
              20                  25                  30        
 Leu Leu Ala Arg Val Phe Leu Ala Leu Cys Asp Asn Pro Lys Asp Arg
          35                  40                  45            
 Gly Thr Ile Val Ala Gln Gly Gly Gly Lys Ala Leu Ile Pro Leu Ala
      50                  55                  60                
 Leu Glu Gly Thr Asp Val Gly Lys Val Lys Ala Ala His Ala Leu Ala
  65                  70                  75                  80
 Lys Ile Ala Ala Val Ser Asn Pro Asp Ile Ala Phe Pro Gly Glu Arg
                  85                  90                  95    
 Val Tyr Glu Val Val Arg Pro Leu Val Arg Leu Leu Asp Thr Gln Arg
             100                 105                 110        
 Asp Gly Leu Gln Asn Tyr Glu Ala Leu Leu Gly Leu Thr Asn Leu Ser
         115                 120                 125            
 Gly Arg Ser Asp Lys Leu Arg Gln Lys Ile Phe Lys Glu Arg Ala Leu
     130                 135                 140                
 Pro Asp Ile Glu Asn Tyr Met Phe Glu Asn His Asp Gln Leu Arg Gln
 145                 150                 155                 160
 Ala Ala Thr Glu Cys Met Cys Asn Met Val Leu His Lys Glu Glu Lys
                 165                 170                 175    
 Ala Phe Ile Ser Met Ser Ser Glu Gln His Asn Leu Glu Leu Asn Lys
             180                 185                 190        
 Pro Ser Gly
         195



      <210> 1761
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 1761
 Met Gly Ile Met Leu Cys Leu Pro Ala Leu Leu Ser Glu Leu Ser Ala
   1               5                  10                  15    
 Cys Tyr Ala Gly Glu Gly Ala Val Cys Gln Phe Ala Pro Gln Asn Ala
              20                  25                  30        
 Ser Gln Lys Pro Phe Gln Asp Pro Phe Ile Val Arg Ala Glu Asn Leu
          35                  40                  45            
 Pro His Arg Ser Arg His Val Asn Leu Tyr Leu Ala His Pro Asp Gly
      50                  55                  60                
 His Gly Ile Ser Met Phe Tyr Ser Thr Phe Ser Leu Glu His Cys Glu
  65                  70                  75                  80
 Gly Gln Ala Gln Gln Met Ala His Gln Phe Asp Gln Asp Arg Glu Leu
                  85                  90                  95    
 Tyr Gly Glu Phe Lys Pro Lys Glu Ser Leu Leu Asn Arg Leu Thr Tyr
             100                 105                 110        
 Pro Asp
        



      <210> 1762
      <211> 132
      <212> PRT
      <213> Homo sapiens


      <400> 1762
 Met Ala Pro Ser Arg Arg Pro Thr Gly Cys Ala Leu Leu Gln Ala Trp
   1               5                  10                  15    
 Gly Leu Ile Leu Thr Ser Pro Arg Gln Gln Gln Pro Phe Ile Phe Pro
              20                  25                  30        
 Thr Lys Gly Arg Glu Asn Lys Arg Trp Lys Ser Arg Thr Phe Ser Thr
          35                  40                  45            
 Leu Glu Pro Ser Ala Gln Ile His Gly Trp Gln Glu Leu Asp Phe Ser
      50                  55                  60                
 Gly Gln Trp Leu Lys Asp Leu Gln Ala Thr Leu Glu Lys Gly His Glu
  65                  70                  75                  80
 Val Ala Ser Asp Thr Ser Ser Ile Ser Cys Ser Trp Gly Ser Leu Leu
                  85                  90                  95    
 Ser Gln Met Val Gln Met Leu Gln Ser Leu Thr Ser Arg His Lys Arg
             100                 105                 110        
 Asn Val Leu Glu Ala Ile Gln His Cys Pro Gln Cys Arg Arg Met Ser
         115                 120                 125            
 Arg Ser Val Cys
     130        



      <210> 1763
      <211> 116
      <212> PRT
      <213> Homo sapiens


      <400> 1763
 Met Thr Ala Cys Trp Gln Pro Ser Leu Thr Leu Gly Ala Ser Ser Ala
   1               5                  10                  15    
 Leu Ala Pro Thr Leu Ala Thr Leu Glu Glu Pro Phe Ser Pro Pro Leu
              20                  25                  30        
 His Cys Gly Ser Pro Phe Leu Gly Trp Pro Arg Pro Glu Pro Ala Pro
          35                  40                  45            
 Ser Ala Cys Gly Glu Val Trp Arg Glu Arg Arg Glu Arg Glu Pro Gly
      50                  55                  60                
 Leu Cys Ala Ala Leu Ala Gly Gln His Thr Thr Gly Thr Ser Pro Gly
  65                  70                  75                  80
 Glu Leu Arg His Ser Asn Thr Pro Leu Ala Glu Thr Pro Thr Ile Leu
                  85                  90                  95    
 Ser Leu Thr Glu Thr Glu Lys Asp Leu Lys Asp Ser Ser His Leu Val
             100                 105                 110        
 Ala Val Lys Gly
         115    



      <210> 1764
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1764
 Met Ser Trp Leu Arg Ala Asp Met Arg Met Arg Met Ala Leu Pro Leu
   1               5                  10                  15    
 Leu Val Gly Ile Ala His Ala Ala Ile Ala Val Asp Val Asp Phe Thr
              20                  25                  30        
 Arg Arg Glu Ala Ile Ala Lys Glu His Val Glu Glu Val Phe Arg Gly
          35                  40                  45            
 Asp Val Ser Leu Lys Ala Val Val Glu Ile Pro Met Thr Met Leu Asp
      50                  55                  60                
 Leu Thr Ala
  65        



      <210> 1765
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1765
 Met Val Gly Asn Val Ser Leu Leu Met His Ser Phe Phe Tyr Leu Ile
   1               5                  10                  15    
 Phe Gln Phe Gly Asp Phe Pro Gly Leu Asp Pro Arg Ser Ser Phe His
              20                  25                  30        
 Cys Cys Glu Ala Phe Thr His Thr Tyr Asp Phe Ser Tyr His Val Glu
          35                  40                  45            
 Val Asp Cys Tyr Ser Asp Asp Ser Phe Met Glu Tyr Leu Leu Leu Leu
      50                  55                  60                
 Asn Tyr Ile Thr Lys Ile Asn Ile Gln Lys Trp Lys Tyr Phe Asp Arg
  65                  70                  75                  80
 Glu Tyr Glu Met Ala Leu Thr Thr Tyr Tyr Cys Ile Val Phe Leu Lys
                  85                  90                  95    
 Gly Tyr Ile Ile Leu Gly Leu Ser Lys Phe
             100                 105    



      <210> 1766
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 1766
 Met Ala Glu Leu Gly Tyr Arg Leu Arg Ala Gly Ser Pro Leu Leu Thr
   1               5                  10                  15    
 Val Leu Ala Val Thr Met Phe Thr Ser Gly Asp Ile Pro Phe Val Thr
              20                  25                  30        
 Gln Asn Leu Ala Ala Lys Gln Leu Gly Val Ala Ser Cys Glu Lys Glu
          35                  40                  45            
 Met Leu Ala Ala Gly Ile Phe Gln Ala Gly Ile Ser Ile Ala Gln Lys
      50                  55                  60                
 Asn Ile Leu Gly Met Phe Pro Ser Ala Arg Gln Ser Glu Gly Leu Ser
  65                  70                  75                  80
 Gly Met Ala Trp Cys Pro Glu Lys Arg Ser Cys Ala Ser Cys Pro His
                  85                  90                  95    
 Pro Ser Pro Thr Leu Pro Pro Glu Ala Ser Leu Thr Ala Leu Asn Ala
             100                 105                 110        
 Gln Cys Gly Tyr Arg Leu Pro Cys Ala Phe Glu Pro Gln Glu Ala Gly
         115                 120                 125            
 Glu Tyr Gly Met Cys Asp Ala
     130                 135



      <210> 1767
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1767
 Met Glu Gln Cys Leu Ala Leu Arg Lys Pro Ser Gly Asn Ala Ile Ser
   1               5                  10                  15    
 Ser Leu Leu Ile Ile Leu Thr Arg Thr Leu Pro Leu Val Ala Ile His
              20                  25                  30        
 Lys Pro Ala Thr Asn Ser Asn Lys Val Leu Asp Ala Pro Phe Val Leu
          35                  40                  45            
 Ile Phe Val Leu Asn Val Pro Glu Gly His Leu Trp Lys Lys Met Gln
      50                  55                  60                
 Val Phe Lys Ser His Gln Leu Gln Ile Met Ala Thr Pro Cys Pro Ala
  65                  70                  75                  80
 Leu Arg Met Glu Ala Lys Thr Ile Pro Ser Glu Ile Val Phe Pro Cys
                  85                  90                  95    
 Gln Asp Gly Asp Cys Val Val Ala Leu Phe
             100                 105    



      <210> 1768
      <211> 204
      <212> PRT
      <213> Homo sapiens


      <400> 1768
 Met Leu Leu Ile Leu Met Leu Ser Leu Ser Phe Asn Glu Gln Pro Val
   1               5                  10                  15    
 Leu Pro Ser Thr His Gln Ala Asp Ser Thr Lys His Gly Arg Gly Leu
              20                  25                  30        
 Ser Pro Glu Ser Pro Arg Cys Arg Val Pro Lys Pro Glu Phe Gln Gln
          35                  40                  45            
 Val Leu Gln Gly Pro Leu Thr Arg Glu His Cys Ala Trp Gly Glu Lys
      50                  55                  60                
 Gly Arg Arg Ala Gly Ala Val Glu Gly Ile Arg Arg Gly Asn Gly Ser
  65                  70                  75                  80
 Ile Pro Gln Gln Gln Gly Ala Arg Pro Ser Val Arg Thr His Pro Ser
                  85                  90                  95    
 Ser Gly Ile Leu Leu Phe Leu Ser Gly Gln Ser Leu Gly Cys Cys Pro
             100                 105                 110        
 Thr Arg Met Glu Arg Ile His Ala Pro Met Val Leu Ser Thr Gly Trp
         115                 120                 125            
 Cys Leu Ala Arg Tyr Thr Ala Asp Leu Leu Glu Val Leu Lys Thr Asn
     130                 135                 140                
 Tyr Gly Ile Pro Ser Ala Cys Phe Ser Gln Pro Pro Thr Ala Ala Gln
 145                 150                 155                 160
 Leu Leu Arg Asp Pro Arg Ala Ile Trp Gly Pro Lys Met Val Pro Lys
                 165                 170                 175    
 Trp Ser Lys Pro His Arg Val Ser Trp Arg Ala Ala Arg His Pro Pro
             180                 185                 190        
 Trp Thr His Val Thr Leu Glu Gly Gly Tyr Gly Glu
         195                 200                



      <210> 1769
      <211> 242
      <212> PRT
      <213> Homo sapiens


      <400> 1769
 Met Ser Ser Val Leu Ser Ala Phe Ser Gly Leu Leu Thr Cys Gly Met
   1               5                  10                  15    
 Val Glu Tyr Leu Phe Val Cys Ser Leu Ser Cys Ser Tyr Tyr Leu Gln
              20                  25                  30        
 Tyr Val Lys Gly Met Pro Ala Pro Ala Met Pro Leu Pro Ala Met Thr
          35                  40                  45            
 Pro Gln Cys Ser Lys Asp Lys Ala Leu Leu Cys Pro Cys Ala Ile Cys
      50                  55                  60                
 Pro Ser Pro Ala Leu Val His Gly Val Tyr Asp Cys Ser Val Thr Pro
  65                  70                  75                  80
 Ala Pro Thr Ser Ser Ala Cys Arg Arg Gly Thr Ala Ala Leu Val Gln
                  85                  90                  95    
 Ala Gly Phe Ser Arg Phe Arg Thr Gln Ile Leu Ser Ile Ser Phe Lys
             100                 105                 110        
 Gln Pro Glu Gln Asn Leu Glu Leu Gly Lys Val Lys Glu Gly Thr Gln
         115                 120                 125            
 His Thr Thr Ala Pro Val Ala Arg Phe Thr Leu Gly Lys Ala Gly Trp
     130                 135                 140                
 Trp Leu Pro Asp Thr Ala Ser Ser His Tyr Phe Gln Lys Cys Pro Glu
 145                 150                 155                 160
 Asn Asn Ser Ile His Val Thr Gln Cys Ala Lys His Arg Tyr Ile Leu
                 165                 170                 175    
 Pro Leu Tyr Cys Pro Gly Ser Leu Pro Lys Val Arg Ala Gly Ser Val
             180                 185                 190        
 His Pro Ser Ser Val Tyr Ser Ile Pro Pro Leu Pro Ala Tyr His Ile
         195                 200                 205            
 Lys Leu Ala Glu Ser Asn Lys Gly Val Ala Pro Gly Thr Arg Gln Pro
     210                 215                 220                
 Gly Leu Gly Ser Gly Cys Ile Arg Ala Gly Ile Trp Leu Tyr His Thr
 225                 230                 235                 240
 Leu Ala
        



      <210> 1770
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 1770
 Met Ser His Arg Thr Arg Leu Thr Gly Gly Phe Leu Thr Leu Phe Gly
   1               5                  10                  15    
 Tyr Ile Thr Ser Val Asn Lys Gly Lys Leu Thr Thr Gly Thr His Thr
              20                  25                  30        
 Lys Lys Glu Glu Asn Ser Thr Asn Lys Met Gly Glu Val Asn Ser Glu
          35                  40                  45            
 Val Phe Leu Ser Ile Ile Lys Ala Glu Ala Val Val Pro Val Gly Pro
      50                  55                  60                
 Ala Asn Arg Ser Gln Met Leu Asn Ser Ala Gly Ser Phe Phe His Gly
  65                  70                  75                  80
 Thr Leu Lys Asn Asp Ala Leu Arg Leu Gly Gln Thr Ser Val Asn Phe
                  85                  90                  95    
 Ser Arg Asp Gly Thr Arg Phe Lys Arg Pro Lys Lys Arg Pro Gly Ala
             100                 105                 110        
 Ser Glu Gly Asn Ile Gly Phe Ile Trp Gly Ile Leu Gln Gly Gly Pro
         115                 120                 125            
 Val Ala Ala Gly Trp Thr Glu Leu Gln Pro Leu Ile Lys Ser Met Gln
     130                 135                 140                
 Phe Thr
 145    



      <210> 1771
      <211> 45
      <212> PRT
      <213> Homo sapiens


      <400> 1771
 Met Leu Pro Phe Thr Ala Val Leu Ser Ala Ala Trp Met Glu Val Glu
   1               5                  10                  15    
 Pro Val Ser Tyr Gly Gln Glu Ala His Ile Ile Lys Ser Val Cys Leu
              20                  25                  30        
 Gln Phe Lys Ala Pro Gly Leu Gly Asp Tyr Leu Leu Glu
          35                  40                  45



      <210> 1772
      <211> 73
      <212> PRT
      <213> Homo sapiens


      <400> 1772
 Met Leu Lys Gln Val Val Gly Leu Glu Gly Leu Leu Cys Val Phe Thr
   1               5                  10                  15    
 Val Val Lys Cys Ser Asn His Leu Ala Pro Lys Ala Cys Ala Ser Ala
              20                  25                  30        
 Gly Ile Ser Ser Gln Ser Thr Leu Cys Gly Pro Val Val Gly Asp Arg
          35                  40                  45            
 Cys Ser Ser Ala Phe Glu Arg Ile His Pro Met Pro Phe Phe Arg Val
      50                  55                  60                
 Ile Phe Thr Ala Ala Val Val Asn Leu
  65                  70            



      <210> 1773
      <211> 56
      <212> PRT
      <213> Homo sapiens


      <400> 1773
 Met Lys Leu Arg Thr Leu Leu Asp Leu Ser Leu Leu Ile Leu Ser Val
   1               5                  10                  15    
 Ile Ser Pro Gly Lys Pro Ser Lys Glu Leu Ser Ser Phe Ser Arg Asp
              20                  25                  30        
 Leu Arg Glu Asn Ser Pro Glu Phe Ser Val His Val Thr Gln Ala Leu
          35                  40                  45            
 Asn Ala Val Thr Cys Thr Glu Arg
      50                  55    



      <210> 1774
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 1774
 Met Tyr Met Leu Leu Gln Ala Phe Trp Leu Trp Gln Glu Thr Leu Lys
   1               5                  10                  15    
 Thr Ile Leu Leu Tyr Lys Phe Thr Lys Pro Pro Ala Asn Thr Pro Val
              20                  25                  30        
 Leu Gly Val Asn Ala Gln Val Cys His Ser Cys Leu Ala Ala Leu Arg
          35                  40                  45            
 Ile Arg Lys Val Asn Gly His Lys Arg Asn Phe Lys Ala Gln Pro Pro
      50                  55                  60                
 Asn Gly Lys Leu Pro Leu Val Leu Gly Cys Leu Cys Leu Leu Thr Asp
  65                  70                  75                  80
 Leu Ile His Ala Leu Gly Tyr Asp Cys Arg Arg Asp Phe Pro Val Ser
                  85                  90                  95    
 Leu Glu Tyr Ala Glu Leu Val Phe Leu Phe Val Val Ala Tyr
             100                 105                 110



      <210> 1775
      <211> 76
      <212> PRT
      <213> Homo sapiens


      <400> 1775
 Met Leu His Leu Leu Gly Met Ala Thr Trp Leu Leu Pro Ala Val Ile
   1               5                  10                  15    
 Lys Thr Arg Ile Ser Gln Trp Arg Pro Ile Val Gly Arg Pro Arg Lys
              20                  25                  30        
 Ala Gly Glu Thr Glu Glu Glu Gly Val Arg Gly Leu Glu Arg Gln Pro
          35                  40                  45            
 Gln Gly Glu Glu Val Arg Gln Glu Glu Arg Gln Met Ala Val His Val
      50                  55                  60                
 Ser His Asp Ser Gln Gly Pro Gly Val Gly Lys His
  65                  70                  75    



      <210> 1776
      <211> 230
      <212> PRT
      <213> Homo sapiens


      <400> 1776
 Met Pro Gly Ser Arg Leu Ser His Thr Pro Ser Tyr Leu Ile Leu Leu
   1               5                  10                  15    
 Leu Pro Pro Pro Pro Leu Leu Pro Leu Val His Lys Pro Leu Leu Gly
              20                  25                  30        
 Ser Leu Ala Ala Ser Arg Phe Leu Lys Met Arg Val Leu Ala Glu Ile
          35                  40                  45            
 Ala Glu Glu Thr Gln Gly Arg Ser Gln Val Ile Ser Leu Cys Pro Asn
      50                  55                  60                
 Pro Gln Asp Thr Gln Ala Ser Ala Ala Val Lys Ser Lys Ala Gln Gly
  65                  70                  75                  80
 Met Leu Glu Gly Glu Gly Ala Ala Gly Gly Lys Gly Leu Arg Arg Ala
                  85                  90                  95    
 Arg Glu Lys Gln Leu Gly Trp Pro Ser Pro Cys Glu Val Val Thr Thr
             100                 105                 110        
 Gly Met Asn Ala Glu Pro Gly Ala Pro Val Leu Val Leu Ala Ala Ser
         115                 120                 125            
 Pro Gly Gln Leu Ala Ser Arg Ala His Trp Gly Cys Thr Ala Val Cys
     130                 135                 140                
 Ile Lys Ala Pro Val Gly Glu Gln Pro Pro Met Ala Gln Ser Asp Gly
 145                 150                 155                 160
 Lys Ser Pro Gly Ala Glu Glu Pro Ser Leu Asp Arg Asn Ile Glu Gly
                 165                 170                 175    
 Lys Leu His Gly Arg Gln Ala Gln Ser Ala Thr Ser Leu Ile Thr Ala
             180                 185                 190        
 Val Leu Ser Ala Glu Leu Gly Leu Gly Leu Asn Ile Ile Leu Lys Pro
         195                 200                 205            
 Val Leu Gln Glu Ser Ser Ala His Gln Ser Ala Ser Gly Pro Glu Ser
     210                 215                 220                
 Lys Pro Val Phe Arg Cys
 225                 230



      <210> 1777
      <211> 100
      <212> PRT
      <213> Homo sapiens


      <400> 1777
 Met Leu Gly Ser Arg Trp Ala Pro Pro Leu Pro Leu Leu Leu Thr Ala
   1               5                  10                  15    
 Leu Glu Pro Ala Leu Leu Gly Pro Ala Leu Gly Gly His Asp Arg Gly
              20                  25                  30        
 Trp Leu Val Asp Ser Ala Pro Leu Gln Ser Pro Gln Glu Ala Val Pro
          35                  40                  45            
 Val Gly Cys Gln Leu Gly Arg Leu Ser Glu Thr Ser Gln Glu Ala Met
      50                  55                  60                
 Ala His Lys Glu Glu Asn Ser Asn Leu Gly Ala Thr Val Ala Ala Leu
  65                  70                  75                  80
 Gln Glu Ala Asn Glu Arg Pro Glu Lys Arg Val Trp Glu Ser Gly Asn
                  85                  90                  95    
 Ala Ala Asp Pro
             100



      <210> 1778
      <211> 276
      <212> PRT
      <213> Homo sapiens


      <400> 1778
 Met Arg Arg Lys Asn Leu Thr Glu Val Thr Glu Phe Val Phe Leu Gly
   1               5                  10                  15    
 Phe Ser Arg Phe His Lys His His Ile Thr Leu Phe Val Val Phe Leu
              20                  25                  30        
 Ile Leu Tyr Thr Leu Thr Val Ala Gly Asn Ala Ile Ile Met Thr Ile
          35                  40                  45            
 Ile Cys Ile Asp Arg His Leu His Thr Pro Met Tyr Phe Phe Leu Ser
      50                  55                  60                
 Met Leu Ala Ser Ser Lys Thr Val Tyr Thr Leu Phe Ile Ile Pro Gln
  65                  70                  75                  80
 Met Leu Ser Ser Phe Val Thr Gln Thr Gln Pro Ile Ser Leu Ala Gly
                  85                  90                  95    
 Cys Thr Thr Gln Thr Phe Phe Phe Val Thr Leu Ala Ile Asn Asn Cys
             100                 105                 110        
 Phe Leu Leu Thr Val Met Gly Tyr Asp His Tyr Met Ala Ile Cys Asn
         115                 120                 125            
 Pro Leu Arg Tyr Arg Val Ile Thr Ser Lys Lys Val Cys Val Gln Leu
     130                 135                 140                
 Val Cys Gly Ala Phe Ser Ile Gly Leu Ala Met Ala Ala Val Gln Val
 145                 150                 155                 160
 Thr Ser Ile Phe Thr Leu Pro Phe Cys His Thr Val Val Gly His Phe
                 165                 170                 175    
 Phe Cys Asp Ile Leu Pro Val Met Lys Leu Ser Cys Ile Asn Thr Thr
             180                 185                 190        
 Ile Asn Glu Ile Ile Asn Phe Val Val Arg Leu Phe Val Ile Leu Val
         195                 200                 205            
 Pro Met Gly Leu Val Phe Ile Ser Tyr Val Leu Ile Ile Ser Thr Val
     210                 215                 220                
 Leu Lys Ile Ala Ser Ala Glu Gly Trp Lys Lys Thr Phe Ala Thr Cys
 225                 230                 235                 240
 Ala Phe His Leu Thr Val Val Ile Val His Tyr Gly Cys Ala Ser Ile
                 245                 250                 255    
 Ala Tyr Leu Met Pro Lys Ser Glu Asn Ser Ile Glu Gln Asp Leu Leu
             260                 265                 270        
 Leu Ser Val Thr
         275    



      <210> 1779
      <211> 280
      <212> PRT
      <213> Homo sapiens


      <400> 1779
 Met Ala Leu Gly Trp Ala Ala Cys Leu Gly Thr Thr Phe Ser Arg Leu
   1               5                  10                  15    
 Cys Leu Tyr Gly Ser Thr Gly Gln Lys Gly Arg Asp Ser Lys Thr Ala
              20                  25                  30        
 Lys Arg Arg Arg Leu Pro Gly Ser Glu Ser Ala Phe Ile Glu Ile Val
          35                  40                  45            
 Phe Gly Val Trp Glu Gln Cys Phe His Met Ile Phe Gly Gly Thr His
      50                  55                  60                
 Phe Lys Lys Asp Glu Asp Pro Val Ile Pro Met Asp Ile Ile Lys Pro
  65                  70                  75                  80
 Ser Pro Val Ile Ala Ser Pro Thr Val Ser Pro Ser Leu Gln Arg Arg
                  85                  90                  95    
 Ala Phe Ser Glu Leu Leu Ser Asp Ala Ser Ala Pro His Ala Ser Ala
             100                 105                 110        
 Phe Pro Met Ala Ile Glu Tyr Asp Ala Ser Ser Gly Pro Pro Met Glu
         115                 120                 125            
 His Ser Pro Leu Ser Ala Phe Gly Leu Tyr Thr Gln Lys Lys Phe Phe
     130                 135                 140                
 Gln Ala Asn His Pro Thr Ser Ser Pro Pro Val Ser Thr Gly Pro Leu
 145                 150                 155                 160
 Lys Ser Arg Cys Gln Gly Gly Ile Arg Cys Ala Arg His Ile Tyr Cys
                 165                 170                 175    
 Val Glu Asn Pro Gly Lys Asp Asn Gly Ala Gly Ala Gly Ile Asp Arg
             180                 185                 190        
 Lys Gly Pro Gln Ile Met Thr Leu Val Lys Gly Glu Arg Glu Arg Arg
         195                 200                 205            
 Lys Thr Gly Leu Glu Ala Pro Gln Arg Trp Ala Ser Thr Ser Val His
     210                 215                 220                
 Thr Met His Asp His Trp Leu Arg Ala Val Tyr Gly Glu His Ala Leu
 225                 230                 235                 240
 Val Thr Asn Gly Val Gly Glu Pro Glu Gly Gln Gly Gln Gly Leu Ala
                 245                 250                 255    
 Val Asn Tyr Ala Pro Gln Ser Arg Ser Glu Arg His Ile Phe Pro Val
             260                 265                 270        
 Thr Ala Ala Gly Gly Phe Arg Val
         275                 280



      <210> 1780
      <211> 159
      <212> PRT
      <213> Homo sapiens


      <400> 1780
 Met His Trp Gly Ala Pro Ser Lys His Leu Ala Leu Ala Ile Leu Pro
   1               5                  10                  15    
 Thr Ser Pro Leu Arg Lys Leu Ala Leu Leu Tyr Ser His Pro His Leu
              20                  25                  30        
 Lys Asn Trp Asp Pro Arg Leu Pro Ser Thr Trp Arg Ser Pro Gly Lys
          35                  40                  45            
 Gly Asp Arg Lys Leu Val Trp Ala Gly Asp Ala Gly Gly Leu Ala Glu
      50                  55                  60                
 Val Arg His Leu Gln Gly Val Phe Arg Ser Arg Thr Ser Asp Ala Lys
  65                  70                  75                  80
 Arg Ala Asp Gly Gly His Arg Arg Arg Ser Pro Arg Ser Leu Phe Ala
                  85                  90                  95    
 Ser Ala Gln Glu Gly Ala Gln Leu Ala Lys Arg Leu Glu Gly Gln Arg
             100                 105                 110        
 Ile Ser Ala Gly Phe Pro Gln Ala Pro Ala Thr Pro Asp Pro Ala Leu
         115                 120                 125            
 Arg Arg Arg Gln Glu Asn Val Cys Arg Glu Ser Leu Glu Gly Thr Val
     130                 135                 140                
 Arg Lys Ser Lys Lys Lys Pro Asn Gln Gln Arg Thr Pro Ala Asn
 145                 150                 155                



      <210> 1781
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1781
 Met Lys Gln Asn Ala Met Leu Lys Arg Ser Arg Phe Leu Leu Leu Leu
   1               5                  10                  15    
 Pro Ser Pro Ala Pro Pro Ala Gln Gln Arg Arg Ala Glu Pro Ser Ala
              20                  25                  30        
 Ala Ala Leu Leu Arg Ser Asp Gln Glu Glu Ala Gly Thr Asp Gly Glu
          35                  40                  45            
 His Ile Trp Lys Gly Glu Met Leu Gln Glu Leu Asp Thr Ala Gly Lys
      50                  55                  60                
 Gly Ser Trp His Thr Ser
  65                  70



      <210> 1782
      <211> 226
      <212> PRT
      <213> Homo sapiens


      <400> 1782
 Met Ala His Trp Ala Val Ser Leu Leu Val Arg Phe Phe Met Lys Ile
   1               5                  10                  15    
 Arg Asp Ser Phe Pro Leu Pro Ile Arg Ser Arg Arg Gly Arg Gly Tyr
              20                  25                  30        
 Pro Arg Pro Leu Ala Pro Thr Leu Ala Val Gln Glu Gln Thr Val Ala
          35                  40                  45            
 Gln Asp Leu Val His Leu His Ser Asp Val Gly Asp Val Leu Gly Asn
      50                  55                  60                
 Ser Leu Asp Pro Leu His Glu Ala Gly Pro Arg Gly His Pro Lys Trp
  65                  70                  75                  80
 Glu Lys Pro Glu Ala Gln Phe Lys Leu Arg Leu Ser Leu Tyr Lys Val
                  85                  90                  95    
 Leu Val Phe Met Ala Ala His Asn Gly Asn Ser Met Lys Asp Phe Ser
             100                 105                 110        
 Asn Leu Gly Ser Val Arg Val Cys Lys Pro His Leu Ser Ser Ser Ser
         115                 120                 125            
 Glu Pro Ser Cys Gln Ser Arg Gly Pro Met Glu Asp Ala Val Gly Trp
     130                 135                 140                
 Ala Pro Gln Lys Gln Ser Leu Gly Gln Gly Phe Glu Gly Thr Phe Cys
 145                 150                 155                 160
 Ala Asp Gly Glu Trp Arg Val Pro Gln Ala Pro Gly Arg Glu Leu Ala
                 165                 170                 175    
 Ser Gln Arg Arg His Gln Glu Ala Glu Ser Glu Glu Ala Asp Ala Gln
             180                 185                 190        
 Asp Lys Lys Pro Ala Glu Arg Lys Glu Ala Gly Gln Glu Gly Arg Lys
         195                 200                 205            
 Gly His Arg Ala Leu Thr Leu His His Val Pro Ala Ala Gln Met Phe
     210                 215                 220                
 Tyr Glu
 225    



      <210> 1783
      <211> 353
      <212> PRT
      <213> Homo sapiens


      <400> 1783
 Met Asn Arg Thr Thr Phe Phe Leu Glu Gly Leu Ser Val Leu Ile Ser
   1               5                  10                  15    
 Ser Trp Phe Arg Leu Leu Arg Gln Lys His Lys Ser His Asp Pro Ser
              20                  25                  30        
 Gly Arg Glu Arg Ala Ala Ser Glu Pro Ala Ser Gln Ser Ser Glu Arg
          35                  40                  45            
 Lys His Arg Thr Arg Gln Glu Pro Ala Arg Gln Lys Gln Pro Gly Glu
      50                  55                  60                
 Ile Tyr Gly Gln Gln Arg Ala Pro Tyr Glu Lys Ser Val Ala Gly Lys
  65                  70                  75                  80
 Arg Gly Pro Pro Gly Ser Tyr Phe Lys Ser Val Leu Arg Asp Val Val
                  85                  90                  95    
 Gly Gly Trp Leu Gly Pro Arg Arg Ser Phe Ala Asn Gln Lys Gln Gly
             100                 105                 110        
 Gly Tyr Lys Asn Asp Arg Gln Glu Thr Gln Arg Thr Arg Lys Leu His
         115                 120                 125            
 Asn Ile Leu Glu Asp Lys Pro Tyr Gly Glu Ile Asn Gln Ile Phe Leu
     130                 135                 140                
 Gln Val Gly Gln Arg Lys Asn Gly Tyr Ala Arg Pro Gln Lys Ser Cys
 145                 150                 155                 160
 Leu Pro Cys Asn Ile Phe Gln Tyr Val Phe Gln Lys Lys Met Lys Glu
                 165                 170                 175    
 Lys Thr Lys Lys Glu Lys Lys Trp Asn Leu Gly Asn Thr Arg Ile Lys
             180                 185                 190        
 Pro Glu Lys Gly Lys Glu Asn Met Gly Lys Val Val Arg Phe Ile Val
         195                 200                 205            
 Arg Ala Lys Leu Thr Cys Val Gly Ser Leu Ile Ile Lys Glu Asp Arg
     210                 215                 220                
 Glu Gln Ala Glu Ala Val Lys Gly Asp Ser Leu Glu Ala Leu Arg Gln
 225                 230                 235                 240
 Val Ala Asn Ala Ser Arg Glu Ala Asp Leu Met Leu Leu Gln Trp Val
                 245                 250                 255    
 Tyr Phe Ser Ser Val Ala Gln Leu Glu Cys Asp Ile Gln Glu Val Asp
             260                 265                 270        
 Cys Gln Ala Cys Lys Leu Arg Glu Lys Tyr Ala Thr Leu Asn His Asp
         275                 280                 285            
 Gly Leu Ile Ser Arg Pro Pro Gly Asn Cys Ile Glu Glu Gly Lys Phe
     290                 295                 300                
 Lys Ala Met Glu Thr Lys Ser Val Leu Thr Gly Phe Thr Val Gly Ile
 305                 310                 315                 320
 Trp Thr Arg Ser Glu Lys Arg Ile Met Val Ser Glu Gln Pro Leu Val
                 325                 330                 335    
 Ala Glu Cys Gln Lys Leu Lys Lys Ser Glu Ala Thr Leu Leu Val Phe
             340                 345                 350        
 Ser
    



      <210> 1784
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1784
 Met Ser Pro Arg Arg Arg Trp Leu Phe Gly Gly Ser Glu Glu Arg Leu
   1               5                  10                  15    
 Leu Leu Leu Leu Leu Leu Leu Val Ala Pro Leu Gln Asn Glu Pro Arg
              20                  25                  30        
 Arg Gln Ser Pro Phe Cys Gln Leu Arg Gly Gly Ala Arg Phe Gly Ser
          35                  40                  45            
 Ala Val Leu Met Ala Arg Ile Tyr Arg Ser Trp Arg Glu Asp Lys Leu
      50                  55                  60                
 Ser Ser Gly Cys Leu Arg Tyr Cys Val Ala Glu Pro Phe Gln
  65                  70                  75            



      <210> 1785
      <211> 64
      <212> PRT
      <213> Homo sapiens


      <400> 1785
 Met Ser Cys Pro Val Pro Asn Phe Ser Asn Gly Arg Phe Thr Thr Phe
   1               5                  10                  15    
 Met Val Ser Cys Phe Phe Lys Thr Ala Arg Val Ser Thr Thr Phe Phe
              20                  25                  30        
 Pro Leu Ala Phe Phe Leu Phe Arg Thr Leu Glu Ser Ile Thr Tyr Pro
          35                  40                  45            
 Leu Ser His Asn Leu Ile Val Ile Asp Ile Glu Cys Leu Cys Ser Asp
      50                  55                  60                





      <210> 1786
      <211> 171
      <212> PRT
      <213> Homo sapiens


      <400> 1786
 Met Ser Pro Leu Arg Ser Met Leu Pro Arg Ala Leu Leu Leu Ser Pro
   1               5                  10                  15    
 Leu Pro Leu Ala Leu Ser Leu Val Lys Arg Ala Ala Pro Phe Pro Arg
              20                  25                  30        
 Phe Pro Ser Gly Phe Ser Trp Phe Arg Gln Pro Gly Gln Thr Ser Leu
          35                  40                  45            
 Leu Pro His Asp Gly Arg Ile Pro Glu Gln Pro Cys Ser Pro Leu Arg
      50                  55                  60                
 Glu Arg Lys Pro Gly Ala Gly Met Asp Ala Pro Ser Thr Lys Cys Asp
  65                  70                  75                  80
 Val Leu Lys Gln Ala Ala Pro Tyr Arg Thr Ala Asn Arg Ala Glu Arg
                  85                  90                  95    
 Ala Pro Leu Leu Pro Ser Ser Ala His Arg Thr Ala Ser Pro Arg Leu
             100                 105                 110        
 Phe Phe Ala Val Cys Leu Cys Gln Val Tyr Pro Thr Pro Pro Lys Ser
         115                 120                 125            
 Pro Leu Leu Ser Ala Asn Thr Ala Val Ser Arg Val Leu Gln Gln Asp
     130                 135                 140                
 Leu Thr Ser Cys Ile Glu Gln Tyr Gly Leu Glu Ala Pro Phe Leu Leu
 145                 150                 155                 160
 Pro His Pro Val Leu Ile Pro Ala Gln Asp Val
                 165                 170    



      <210> 1787
      <211> 293
      <212> PRT
      <213> Homo sapiens


      <400> 1787
 Met Val Leu Leu Leu Leu Val Ala Ile Pro Leu Leu Val His Ser Ser
   1               5                  10                  15    
 Arg Gly Pro Ala His Tyr Glu Met Leu Gly Arg Cys Arg Met Val Cys
              20                  25                  30        
 Asp Pro His Gly Pro Arg Gly Pro Gly Pro Asp Gly Ala Pro Ala Ser
          35                  40                  45            
 Val Pro Pro Phe Pro Pro Gly Ala Lys Gly Glu Val Gly Arg Arg Gly
      50                  55                  60                
 Lys Ala Gly Leu Arg Gly Pro Pro Gly Pro Pro Gly Pro Arg Gly Pro
  65                  70                  75                  80
 Pro Gly Glu Pro Gly Arg Pro Gly Pro Pro Gly Pro Pro Gly Pro Gly
                  85                  90                  95    
 Pro Gly Gly Val Ala Pro Ala Ala Gly Tyr Val Pro Arg Ile Ala Phe
             100                 105                 110        
 Tyr Ala Gly Leu Arg Arg Pro His Glu Gly Tyr Glu Val Leu Arg Phe
         115                 120                 125            
 Asp Asp Val Val Thr Asn Val Gly Asn Ala Tyr Glu Ala Ala Ser Gly
     130                 135                 140                
 Lys Phe Thr Cys Pro Met Pro Gly Val Tyr Phe Phe Ala Tyr His Val
 145                 150                 155                 160
 Leu Met Arg Gly Gly Asp Gly Thr Ser Met Trp Ala Asp Leu Met Lys
                 165                 170                 175    
 Asn Gly Gln Gly Trp Gly Pro Arg Thr Ala Leu Pro Ser Ala Glu Ser
             180                 185                 190        
 Val Ala Trp Gln Leu Lys Gly Gln Pro Gly Ala Ser Ala Ile Ile Cys
         195                 200                 205            
 Leu Leu Arg Val Thr Val Ile Gln Trp Glu Ser Leu Val Val Pro Pro
     210                 215                 220                
 Phe Ser Thr Tyr Gly Cys Gly Pro Gln Glu Asp Asp Gly Leu Arg Phe
 225                 230                 235                 240
 Cys Ser Gly Ala Ser Pro Val Ala Gly Asn Cys Asn Pro Gln Asp Asp
                 245                 250                 255    
 Ala Arg Ala Gln Leu Pro Ser Phe Tyr Val Ala Glu Phe Met Leu Pro
             260                 265                 270        
 Cys Thr Glu Gln Thr Leu Ser Leu Thr Gln Pro Cys Pro Ser Pro Cys
         275                 280                 285            
 Pro Val Ile Pro Glu
     290            



      <210> 1788
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 1788
 Met Ala Ile Gln Arg Val Leu Gln Ile Gln Glu Arg Leu Met Ser Trp
   1               5                  10                  15    
 Leu Phe Val Val Ile Asp Arg Val Cys Ser Ser Ser Gln Gly Val Phe
              20                  25                  30        
 Met Thr Gly Trp Lys Cys Asp Leu Gly Lys Gln Glu Ala Val Ala Gly
          35                  40                  45            
 Glu Asn Asn Leu Ser Glu His Glu Lys Lys Ala Thr Gln Thr Thr Pro
      50                  55                  60                
 Gln Pro Ser Asp Ser Pro Glu Ile Trp Tyr Arg Ser Ala Ser Lys Thr
  65                  70                  75                  80
 Leu Gly Trp Met Asp Gln Cys Phe Pro Asp Leu Pro Asp Pro Lys Glu
                  85                  90                  95    
 His Leu Gly His Leu Leu Glu His Arg Cys Gln Ala Pro Ala Leu Glu
             100                 105                 110        
 Leu Leu Leu Pro Gln Ile Cys Thr His Leu Gly Asn Thr Arg Ser Asp
         115                 120                 125            
 Glu Phe Gly Gln Val Leu
     130                



      <210> 1789
      <211> 309
      <212> PRT
      <213> Homo sapiens


      <400> 1789
 Met Ala Ala Phe Ala Ala Gly Pro Leu Cys Met Pro Val Cys His Leu
   1               5                  10                  15    
 Cys Val Ser Leu Asp Val Ala Gln Trp Asn Ile Gly Ser Leu Arg Thr
              20                  25                  30        
 Ile Leu Asp Met Val Glu Arg Glu Cys Gly Thr Ile Ile Glu Gly Val
          35                  40                  45            
 Asn Thr Pro Tyr Leu Tyr Phe Gly Met Trp Lys Thr Thr Phe Ala Trp
      50                  55                  60                
 His Thr Glu Asp Met Asp Leu Tyr Ser Ile Asn Tyr Leu His Phe Gly
  65                  70                  75                  80
 Glu Pro Lys Ser Trp Asp Arg Leu Pro Cys Ala Glu Ser Pro Cys Gly
                  85                  90                  95    
 Ala Gly Ser Gly Glu Gln Pro Ala Arg Arg Pro Ser Gln Thr Glu Ala
             100                 105                 110        
 Gly Gly Ser Gly Thr Trp Glu Val Gly Asp Gln Pro Ala Ala Gly Leu
         115                 120                 125            
 Arg Ile Ser Glu Glu Thr Glu Arg Leu Lys Ile Ser Leu Ala Met Arg
     130                 135                 140                
 Ile Glu Thr Arg Ala Ser Thr Cys Asn Phe Pro Pro Pro Thr Ser Arg
 145                 150                 155                 160
 Ser Pro Phe Cys His Pro Gly Arg Gly Gly Arg Ser Ala Gly Asp Cys
                 165                 170                 175    
 Gly Pro Pro Pro Arg Ala Glu Ala Leu Ala Leu Thr Ala Ala Gly Lys
             180                 185                 190        
 Pro Asp Gly Gly Ser Ala Cys Ser Trp Gly Cys Arg Asp Ser Arg Gly
         195                 200                 205            
 Arg Arg Glu Leu Met Gly His Gly Gln Leu Leu Ala Leu Ala Pro Arg
     210                 215                 220                
 Arg Arg Glu Glu Gly Pro Pro Glu Glu Cys Arg Gly Ala Ser Ala Val
 225                 230                 235                 240
 Trp Leu Gln Val Ala Leu Ser Gly Pro Thr Met Ala Ser Ala Leu Ser
                 245                 250                 255    
 Leu Gly Val Gly Pro Arg Ser Leu Val Gly Asp Gly Ala Gly Glu Pro
             260                 265                 270        
 Val Pro Gly Ser Ser Leu Lys Ala His Gly Val Ala Arg Trp Arg Pro
         275                 280                 285            
 Gly Thr Leu Val Trp Val Cys Thr Ala Ala Ala Gly Glu Pro Thr Thr
     290                 295                 300                
 Gly Thr Ser Ser Phe
 305                



      <210> 1790
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1790
 Met Leu Pro Val Phe Met Leu Leu Leu Pro Met Ala Cys Ala Leu Ser
   1               5                  10                  15    
 Arg Gln Gly Tyr Asn Tyr Lys Ser Pro Ser Thr Asn Lys Asn Asn Gly
              20                  25                  30        
 Cys Ile Gln Gln Leu Asp Ser Pro Phe Val Lys Leu Tyr Thr Asp Thr
          35                  40                  45            
 Val Leu Asn Ala Glu Ala Asn Gln Asn Pro Glu Ile Leu Lys Tyr Gly
      50                  55                  60                
 Ile Tyr Asn Tyr Lys Lys Gln Gln Glu Thr Lys Glu Glu Tyr Lys Tyr
  65                  70                  75                  80
 Asn His Ala Leu Cys Phe Lys Thr Phe
                  85                



      <210> 1791
      <211> 113
      <212> PRT
      <213> Homo sapiens


      <400> 1791
 Met Asn Ser Leu Ser Trp Gly Ala Ala Asn Ala Val Leu Leu Leu Leu
   1               5                  10                  15    
 Leu Leu Ala Trp Ala Ser Pro Thr Phe Ile Ser Ile Asn Arg Gly Val
              20                  25                  30        
 Arg Val Met Lys Gly His Ser Ala Phe Leu Ser Gly Asp Asp Leu Lys
          35                  40                  45            
 Phe Ala Ile Pro Lys Glu Lys Asp Ala Cys Lys Val Glu Val Val Met
      50                  55                  60                
 Asn Glu Pro Ile Thr Gln Arg Val Gly Lys Leu Thr Pro Gln Val Phe
  65                  70                  75                  80
 Asp Cys His Phe Leu Pro Asn Glu Val Lys Tyr Val His Asn Gly Cys
                  85                  90                  95    
 Pro Ile Leu Asp Glu Asp Thr Val Lys Leu Arg Leu Tyr Ser Val Leu
             100                 105                 110        
 Ile
    



      <210> 1792
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 1792
 Met Leu Val Val Tyr Ser Ser Ala Thr Val Val Arg Leu Leu Pro Cys
   1               5                  10                  15    
 Ala Cys Phe His Leu Glu Leu Ser Leu Leu Gln Phe Cys Glu Asp Ala
              20                  25                  30        
 Ala Tyr Asp Trp Val Thr Asp Thr Pro Glu Ile Arg Ile Lys Ser Lys
          35                  40                  45            
 Leu Asn Lys Thr His Arg Val Gln Arg Asp Phe Asp Lys Asp Arg Lys
      50                  55                  60                
 Leu Ala Val Gly Gln Ser Glu Ser Pro Gly His Pro Thr Ser Glu Lys
  65                  70                  75                  80
 Pro Pro Ser Thr Ser Ser Ser Ala Gly Ser Pro Glu Ala Phe Arg Lys
                  85                  90                  95    
 Leu Ile Gln Tyr Leu Ala Pro Arg Arg Pro Cys His
             100                 105            



      <210> 1793
      <211> 413
      <212> PRT
      <213> Homo sapiens


      <400> 1793
 Met Val Ser Val Val Gly Ala Gly His Gln Arg Glu Leu Leu His Ala
   1               5                  10                  15    
 Trp Leu Leu Gly Ala Arg Ala Cys Gly Pro Leu Ala Cys Leu Thr Val
              20                  25                  30        
 Val Gly Gly Gly Ser Asp Arg Asp Cys Ser Met Thr Arg Val Val Gly
          35                  40                  45            
 Gln Gly Leu Ser Arg Ala Ala Pro Phe Ala Val Trp Gly Pro Ala Pro
      50                  55                  60                
 Ala Ala Ala Leu Ala Leu Ala Trp Asn Leu Val Leu Ser Arg Thr Cys
  65                  70                  75                  80
 Pro Asp Ser Ala Met Ala Leu Ala Leu Leu Cys Leu Val Pro Gly Pro
                  85                  90                  95    
 Asp Pro Asp Pro Asp Pro Phe Leu Ala Leu His Trp Ser Phe Pro Gly
             100                 105                 110        
 Pro Glu Leu Ala Val Val Cys Pro Cys Phe Gly Pro Glu Val Asp Leu
         115                 120                 125            
 Glu Val Ser Trp Pro Arg Cys Asn Met Ala Leu His Trp Pro Val Ser
     130                 135                 140                
 Ala Leu Pro Leu Pro Ser Pro Cys Pro Ala Leu Pro Cys Pro Ser Thr
 145                 150                 155                 160
 Asp Pro Ala Thr Leu Phe Pro Arg Pro Thr Leu Pro Trp Leu Cys Pro
                 165                 170                 175    
 Gly Ser Val Leu Ala Leu Ala Pro Ala Leu Pro Trp Thr Cys Ser Asp
             180                 185                 190        
 Thr Ala Ser Ala Leu Ala Leu Ala Trp Leu Ile Leu Gly Ile Ser Pro
         195                 200                 205            
 Ala Leu Ser Val Asp Arg Leu Leu Ser Cys Pro Ala Leu Ala Ile Pro
     210                 215                 220                
 Cys Pro Ala Leu Pro Cys Pro Asp Ser Ala Leu Thr Gln Pro Trp Pro
 225                 230                 235                 240
 Trp His Cys Pro Trp Ser Cys His Ile Ser Cys Pro Val Pro Thr Leu
                 245                 250                 255    
 Ala Leu Ala Leu Thr Leu Thr Leu Leu Trp Pro Cys Pro Cys Pro Asn
             260                 265                 270        
 Ala Ala Pro Gly Pro Val Met Thr Leu Pro Trp Thr Cys Pro Gly Pro
         275                 280                 285            
 Gly Pro Ser Leu Leu Glu Thr Leu Pro Trp Phe Ser His Gly Pro Asp
     290                 295                 300                
 Pro Glu Met Pro Gly Pro Thr Leu Ala Leu Pro Cys Ser Gly Pro Cys
 305                 310                 315                 320
 Pro Asp Ser Gly Pro Val Thr Asp Leu Ala Pro Ala Leu Leu Leu Val
                 325                 330                 335    
 Leu Pro Trp Pro Arg Pro Cys Leu Gly Pro Ala Leu Thr Leu Ser Trp
             340                 345                 350        
 Thr Leu Ala Val Pro Arg Thr Cys Thr Val Leu Ala Leu Val Leu Leu
         355                 360                 365            
 Leu Pro Gln Thr Trp Ser Cys Pro Gly Arg Phe Tyr Gly Pro Gly Pro
     370                 375                 380                
 Gly Pro Ala Gln Val Leu Ala Leu Ala Trp Pro Cys Pro Gly Pro Ala
 385                 390                 395                 400
 Leu Pro Trp Pro Tyr Ala Phe Leu Ala Leu Pro Trp Pro
                 405                 410            



      <210> 1794
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1794
 Met Gly Pro Thr Ser Gly Pro Ser Leu Leu Leu Leu Leu Leu Thr His
   1               5                  10                  15    
 Leu Pro Leu Ala Leu Gly Ser Pro Ile Cys Gly Arg Leu Arg Pro Val
              20                  25                  30        
 Glu Ser Ala Glu Leu Ser Pro Gly Thr Leu Cys Ser Gln Glu Leu His
          35                  40                  45            
 Ala Gly Gln Gly Ser Gly Ala Thr Val Ser Leu Gln Ile Trp His Ile
      50                  55                  60                
 Trp Gly Gly Gln Glu Lys Thr Pro Leu Gly Trp Ala Leu His Gly Val
  65                  70                  75                  80
 Leu Gly Tyr Ile Asn Lys Pro Glu Arg Asp Lys Asp Pro Cys Pro Met
                  85                  90                  95    
 Gly Ala Asn Ser Pro Arg Glu Asp Asn Lys Pro
             100                 105        



      <210> 1795
      <211> 240
      <212> PRT
      <213> Homo sapiens


      <400> 1795
 Met Trp Leu Leu Pro Ala Leu Leu Leu Leu Cys Leu Ser Gly Asn Thr
   1               5                  10                  15    
 Gln Val Ser Leu Ala Ile Phe Pro Leu Ser Phe Arg Gln Thr Ala Ala
              20                  25                  30        
 Asp Gly Ala Ile Trp Met Glu Thr Trp Asp Ser Gly Leu Cys Phe Pro
          35                  40                  45            
 Gly Cys Leu Ser Leu Lys Gly Pro Gly Ser Val Thr Gly Thr Ala Gly
      50                  55                  60                
 Asp Ser Leu Thr Val Trp Cys Gln Tyr Glu Ser Met Tyr Lys Gly Tyr
  65                  70                  75                  80
 Asn Lys Tyr Trp Cys Arg Gly Gln Tyr Asp Thr Ser Cys Glu Ser Ile
                  85                  90                  95    
 Val Glu Thr Lys Gly Glu Glu Lys Val Glu Arg Asn Gly Arg Val Ser
             100                 105                 110        
 Ile Arg Asp His Pro Glu Ala Leu Ala Phe Thr Val Thr Met Gln Asn
         115                 120                 125            
 Leu Asn Glu Asp Asp Ala Gly Ser Tyr Trp Cys Lys Ile Gln Thr Val
     130                 135                 140                
 Trp Val Leu Asp Ser Trp Ser Arg Asp Pro Ser Asp Leu Val Arg Val
 145                 150                 155                 160
 Tyr Val Ser Pro Ala Ile Thr Thr Pro Arg Arg Thr Thr His Pro Ala
                 165                 170                 175    
 Thr Pro Pro Ile Phe Leu Val Val Asn Pro Gly Arg Asn Leu Ser Thr
             180                 185                 190        
 Gly Glu Val Leu Thr Gln Asn Ser Gly Phe Arg Leu Ser Ser Pro His
         195                 200                 205            
 Phe Leu Leu Val Val Leu Leu Lys Leu Pro Leu Leu Leu Ser Met Leu
     210                 215                 220                
 Gly Ala Val Phe Trp Val Asn Arg Pro Gln Trp Ala Pro Pro Gly Arg
 225                 230                 235                 240





      <210> 1796
      <211> 265
      <212> PRT
      <213> Homo sapiens


      <400> 1796
 Met Pro Pro Ala Pro Lys Ala Phe Ser Gly Leu Leu Leu Phe Leu Cys
   1               5                  10                  15    
 Ile Gln Ala Cys Gly Phe Thr Pro Thr Gln Asn Trp Gln Ile Asn Phe
              20                  25                  30        
 Ile His Met Pro His Val Cys Lys Phe Lys Tyr Leu Leu Val Trp Ile
          35                  40                  45            
 Asn Thr Phe Ala Gly Trp Ile Glu Ala Phe Pro Thr Ser Ser Glu Lys
      50                  55                  60                
 Ala Thr Ala Val Ile Tyr Ser Leu Leu Thr Asp Ile Ile Pro Leu Arg
  65                  70                  75                  80
 Gly Leu Pro Thr Ser Ile Gln Ser Asp Asn Gly Leu Ala Phe Ile Ser
                  85                  90                  95    
 Gln Ile Thr Gln Ala Val Ser Gln Ala Leu Asp Ile Gln Trp Lys Leu
             100                 105                 110        
 His Ile Pro Tyr His Pro Gln Ser Pro Gly Lys Val Glu Trp Met Asn
         115                 120                 125            
 Gly Leu Leu Lys Thr Asn Leu Thr Lys Leu Asn Leu Gln Leu Lys Lys
     130                 135                 140                
 Asp Trp Thr Leu Leu Leu Pro Leu Ala Leu Leu Arg Ile Arg Ala Cys
 145                 150                 155                 160
 Leu Arg Tyr Ala Ile Gly Tyr Ser Pro Phe Lys Leu Leu Tyr Gly Cys
                 165                 170                 175    
 Thr Phe Leu His Gly Pro Asn Leu Val Pro Asp Thr Ser Pro Leu Gly
             180                 185                 190        
 Asn Tyr Leu Pro Val Leu Gln Gln Ala Arg Gln Glu Ile Arg Gln Ala
         195                 200                 205            
 Ala Asn Leu Leu Leu Pro Thr Pro Asp Ser Gln Pro Tyr Lys Asp Thr
     210                 215                 220                
 Leu Ala Gly Arg Ser Val Leu Val Lys Ser Leu Thr Pro Gln Thr Leu
 225                 230                 235                 240
 Gln Pro Trp Trp Thr Arg Pro Tyr Leu Val Ile Tyr Ser Thr Pro Thr
                 245                 250                 255    
 Ala Val His Leu Gln Asp Pro Pro His
             260                 265



      <210> 1797
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 1797
 Met Val Leu Ile Leu Arg Phe Leu Thr Val Ile Arg Gly Thr Asn Met
   1               5                  10                  15    
 Glu Glu Ala Arg Leu His Pro Arg Glu Ile Asn Ser His Val Ala His
              20                  25                  30        
 Thr Lys Pro Val Trp Trp Ser Leu His Thr Asp Thr His Glu Ile Trp
          35                  40                  45            
 Cys Cys Asp Ser Asp Arg Gly Thr Ser Leu Arg Arg Ser Ile Pro Cys
      50                  55                  60                
 Pro Pro Ala Phe Cys Ser Trp Leu Lys Thr Asp Ala Ala Arg Ser Pro
  65                  70                  75                  80
 Arg Lys Pro Leu Asp His His Gly Cys Arg Ala Ser Ala Met Gln Glu
                  85                  90                  95    
 Trp Thr His Ala Glu Asn Trp Tyr Lys Glu Trp Asp Ile Val Thr Lys
             100                 105                 110        
 Ile Pro Glu Asn Val Glu Ala Ala Leu Glu Phe Gly Asn Arg Gln Arg
         115                 120                 125            
 Leu Glu Asp Cys Gly Gly Leu Ser Arg Arg Lys Glu Asp Glu Gly Lys
     130                 135                 140                
 Phe Gly Asn Ser
 145            



      <210> 1798
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1798
 Met Glu Tyr Val Ser Ser Pro Arg Ser Ser Val Glu Arg Thr Val Leu
   1               5                  10                  15    
 Thr Leu Val Thr Val Asp Ala Val Leu Ala Leu Gly Ala Gly Leu Ala
              20                  25                  30        
 Gly Cys Ala Ala Glu Ala Leu Pro Thr Leu Thr His Thr Cys Ala Ile
          35                  40                  45            
 His Ser Ile Gln Thr Asp Ala Ile Thr Lys Ala Asp Ile Leu Gly Ile
      50                  55                  60                
 Pro Trp Thr Gly Leu Ala Leu Gly Ala Lys Glu Ala Gly Thr Ala Phe
  65                  70                  75                  80
 Ser Arg Leu Lys Gln Lys Asp Lys Ala
                  85                



      <210> 1799
      <211> 101
      <212> PRT
      <213> Homo sapiens


      <400> 1799
 Met Leu Leu Thr Gln Ser Lys Ile Lys Cys Cys Val Phe Asn Leu Ser
   1               5                  10                  15    
 Val Leu Phe Phe Gly Leu Val Ser Cys Tyr Glu Val Cys Ser Leu Pro
              20                  25                  30        
 Asp Leu Asn Leu Lys Gln Gln Phe Gln Val Val Lys Ser Val Leu Leu
          35                  40                  45            
 His Phe Ile Leu Lys Ser Ser Asp His Ala Phe Tyr Asp Phe Leu Ser
      50                  55                  60                
 Pro Ala Ser Ser Glu Val Phe Cys Met Asn Ala Cys Gly Asn Met Cys
  65                  70                  75                  80
 Gly Leu Leu Phe Gln Arg Lys Ile Asn Arg Leu Ala Trp Leu Glu Gln
                  85                  90                  95    
 Arg Ala Gly Leu Lys
             100    



      <210> 1800
      <211> 47
      <212> PRT
      <213> Homo sapiens


      <400> 1800
 Met Ile Leu Leu Ser Leu Ser Leu Leu Asn Asn Thr Ala Leu Met Phe
   1               5                  10                  15    
 Lys Leu Leu Glu Leu Gln Val Phe Lys Val Phe Ala Phe Asn Ile Gln
              20                  25                  30        
 Gln Val Ser Ile Leu Trp Arg Lys Val Asn Glu Asn Lys Thr His
          35                  40                  45        



      <210> 1801
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 1801
 Met Ser Gln Arg Val Arg Pro Ile Ala Leu Phe Leu Ser Leu Gly Leu
   1               5                  10                  15    
 Lys Ser Met Leu Pro Val Gly Leu Gln Ser Pro Leu Thr Ala Gln Asp
              20                  25                  30        
 Ala His Leu Pro Gln Leu Pro Val Ala Val Val Glu Ala Val Pro Ala
          35                  40                  45            
 Val Val Arg Ala Ile Val Thr Tyr Ile Gln Ala Asn Cys Gln Gly Lys
      50                  55                  60                
 Ile Val Thr Phe Gly Trp Ala His His Leu Val Asn Val Thr Leu Leu
  65                  70                  75                  80
 Phe Phe Leu Cys Pro Ala Leu Ser Gly Asp Cys Asp Lys Phe Leu Gly
                  85                  90                  95    
 Gln Ser Ala Val Gln Tyr Asp Ser Ala Leu Ser Trp Ala Leu Leu Ser
             100                 105                 110        
 Gly Ser Ile Val Thr Tyr Cys Gln Ala Gln His Leu Gly Glu Ile Val
         115                 120                 125            
 Ala Tyr Thr Trp Val Gln Ile Thr Gly Thr Met Met Thr Leu Leu Pro
     130                 135                 140                
 Gly His Ser Gln Trp Phe Gly Asp Ser Gln Thr Met Ile Gln Gln Thr
 145                 150                 155                 160
 Cys Glu Ala Val Ser Ser Leu Ser Glu His Asn Leu Gln Val Leu Leu
                 165                 170                 175    
 Gly Trp Gln Gln Val Tyr Thr Ser Leu Gly Trp Arg Ser Gln Arg Lys
             180                 185                 190        
 Gly His Ala Ala Ile Val Ala Val Leu Gln His Ser Val Val Ile Thr
         195                 200                 205            
 Ser Ser Thr Gly Lys Ser Glu Val Thr Arg Asn Cys Ser Gly His Pro
     210                 215                 220                
 Ala Tyr Cys Ser Arg Pro Ser Glu Val Val Gly Leu Leu His Thr Val
 225                 230                 235                 240
 Leu Ser Ala Ile Ser Arg Gln Leu Ser Glu Lys Ile Gly Pro Asp Ala
                 245                 250                 255    
 Ala Thr Ala Ala Val His Gly Ala Gly Ala Pro Cys Asn Leu Val Ser
             260                 265                 270        
 Ser Val Asn Thr Trp Glu Phe Met Glu Arg Gly Ser Val Leu Leu Val
         275                 280                 285            
 Thr Leu Leu Ala Ile Val Phe Asp Lys Val Pro Thr Lys Pro Lys Thr
     290                 295                 300                
 Gly Gly Arg Arg Glu Lys Arg Phe Asp Ser Glu Ser Pro Thr Pro Arg
 305                 310                 315                 320
 Leu Tyr Val Glu Lys Pro Thr Ala Ala Arg Gly Arg Gln Arg Gly His
                 325                 330                 335    
 Asn Arg Ser Val Phe Val Ser Ser Gln Asn Gln Pro His Tyr Phe
             340                 345                 350    



      <210> 1802
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1802
 Met Thr Ile Val Val Ile Cys Ser Val Leu Ala Ser Cys Gln Arg Gly
   1               5                  10                  15    
 Pro Gln Thr Thr Gly Phe Cys Glu His Asp Ser Lys Val Lys His Phe
              20                  25                  30        
 Ser Tyr Ile His Asn Cys Gln Lys Gly Ser Asn Gly Gln Ile Leu Glu
          35                  40                  45            
 Glu Asn Asp Thr Val Ala Gln Pro Ser Ala Arg Arg Thr His Thr Gly
      50                  55                  60                
 Glu Ser Pro Tyr Thr Cys Asn Asp Cys Gly Lys Ser Leu Ser Lys Asn
  65                  70                  75                  80
 Tyr Asn Leu Ile Val His Gln Lys Ile His Thr Gly Glu Lys Ser Tyr
                  85                  90                  95    
 Lys Cys Lys Lys Ser His Thr Val Glu Ile Leu Phe Glu Cys Asn Glu
             100                 105                 110        
 Cys Glu Lys Ser Phe Ser Asp Val Ser Asn Leu Ile Val His Leu Arg
         115                 120                 125            
 Ile His Met
     130    



      <210> 1803
      <211> 171
      <212> PRT
      <213> Homo sapiens


      <400> 1803
 Met Ala Leu Leu Ala Leu Leu Leu Val Val Ala Leu Pro Arg Val Trp
   1               5                  10                  15    
 Thr Asp Ala Asn Leu Thr Ala Arg Gln Arg Asp Pro Glu Asp Ser Gln
              20                  25                  30        
 Arg Thr Asp Glu Gly Asp Asn Arg Val Trp Cys His Val Cys Glu Arg
          35                  40                  45            
 Glu Asn Thr Phe Glu Cys Gln Asn Pro Arg Arg Cys Lys Trp Thr Glu
      50                  55                  60                
 Pro Tyr Cys Val Ile Ala Ala Val Thr Met Glu Arg Pro Lys Pro Glu
  65                  70                  75                  80
 Glu Lys Arg Phe Leu Leu Glu Glu Pro Met Pro Phe Phe Tyr Leu Lys
                  85                  90                  95    
 Cys Cys Lys Ile Arg Tyr Cys Asn Leu Glu Gly Pro Pro Ile Asn Ser
             100                 105                 110        
 Ser Val Phe Lys Glu Tyr Ala Gly Ser Met Val Leu Ala Val Glu Lys
         115                 120                 125            
 Ser Lys Ile Lys Met Pro Thr Asp Leu Met Ser Gly Glu Gly Leu Phe
     130                 135                 140                
 Leu Ile Asp Gly Thr Phe Tyr Val Ser Leu Glu Arg Pro Lys Glu Ala
 145                 150                 155                 160
 Lys Thr Phe Pro Ser Val Ser Phe Ile Lys Ala
                 165                 170    



      <210> 1804
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 1804
 Met Ala Val Ser Ser Tyr Trp Val Met Pro Gly Ala Ser Ala Ile Ile
   1               5                  10                  15    
 Cys Leu Leu Arg Val Thr Val Ile Gln Trp Glu Ser Leu Val Val Pro
              20                  25                  30        
 Pro Phe Ser Thr Tyr Gly Cys Gly Arg Arg Lys Met Thr Val Met Lys
          35                  40                  45            
 Ala Arg Gly Arg Thr Thr Val His Ser Val
      50                  55            



      <210> 1805
      <211> 348
      <212> PRT
      <213> Homo sapiens


      <400> 1805
 Met Ser Gln Asp Leu Leu Trp Pro Thr Leu Cys Val Leu Gly Thr Val
   1               5                  10                  15    
 Leu Ser Arg Phe Ile Pro Cys Cys Ser Cys Leu Tyr Phe Gln Ala Arg
              20                  25                  30        
 Thr Ile Ile Leu Ser Thr His His Leu Asp Glu Ala Glu Val Leu Ser
          35                  40                  45            
 Asp Arg Ile Ala Phe Leu Glu Gln Gly Gly Leu Arg Cys Cys Gly Ser
      50                  55                  60                
 Pro Phe Tyr Leu Lys Glu Ala Phe Gly Asp Gly Tyr His Leu Thr Leu
  65                  70                  75                  80
 Thr Lys Lys Lys Ser Pro Asn Leu Asn Ala Asn Ala Val Cys Asp Thr
                  85                  90                  95    
 Met Ala Val Thr Ala Met Ile Gln Ser His Leu Pro Glu Ala Tyr Leu
             100                 105                 110        
 Lys Glu Asp Ile Gly Gly Glu Leu Val Tyr Val Leu Pro Pro Phe Ser
         115                 120                 125            
 Thr Lys Val Ser Gly Ala Tyr Leu Ser Leu Leu Arg Ala Leu Asp Asn
     130                 135                 140                
 Gly Met Gly Asp Leu Asn Ile Gly Cys Tyr Gly Ile Ser Asp Thr Thr
 145                 150                 155                 160
 Val Glu Glu Val Phe Leu Asn Leu Thr Lys Glu Ser Gln Lys Asn Ser
                 165                 170                 175    
 Ala Met Ser Leu Glu His Leu Thr Gln Lys Lys Ile Gly Asn Ser Asn
             180                 185                 190        
 Ala Asn Gly Ile Ser Thr Pro Asp Asp Leu Ser Val Ser Ser Ser Asn
         195                 200                 205            
 Phe Thr Asp Arg Asp Asp Lys Ile Leu Thr Arg Gly Glu Arg Leu Asp
     210                 215                 220                
 Gly Phe Gly Leu Leu Leu Lys Lys Ile Met Ala Ile Leu Ile Lys Arg
 225                 230                 235                 240
 Phe His His Thr Arg Arg Asn Trp Lys Gly Leu Ile Ala Gln Val Ile
                 245                 250                 255    
 Leu Pro Ile Val Phe Val Thr Thr Ala Met Gly Leu Gly Thr Leu Arg
             260                 265                 270        
 Asn Ser Ser Asn Ser Tyr Pro Glu Ile Gln Ile Ser Pro Ser Leu Tyr
         275                 280                 285            
 Gly Thr Ser Glu Gln Thr Ala Phe Tyr Ala Gln Cys Leu Asn Lys Asp
     290                 295                 300                
 Ser Leu Glu Lys Trp Asn Thr Ser Gly Glu Pro Ile Thr Asn Phe Gly
 305                 310                 315                 320
 Val Cys Ser Cys Ser Glu Asn Val Gln Asp Gln Phe Pro Lys Val Gly
                 325                 330                 335    
 Asn Ser Met Met Val Phe Val Glu Thr Asn Arg Lys
             340                 345            



      <210> 1806
      <211> 470
      <212> PRT
      <213> Homo sapiens


      <400> 1806
 Met Arg Arg Leu Pro Arg Ala Leu Leu Leu Gln Leu Arg Leu Ala Leu
   1               5                  10                  15    
 Leu Val Ala Ala Gly Ala Pro Glu Val Leu Val Ser Ala Pro Arg Ser
              20                  25                  30        
 Leu Val Trp Gly Pro Gly Leu Gln Ala Ala Val Val Leu Pro Val Arg
          35                  40                  45            
 Tyr Phe Tyr Leu Gln Ala Val Asn Ser Glu Gly Gln Asn Leu Thr Arg
      50                  55                  60                
 Ser Pro Ala Gly Glu Thr Pro Phe Lys Val Val Val Lys Ser Leu Ser
  65                  70                  75                  80
 Pro Lys Glu Leu Val Arg Ile His Val Pro Lys Pro Leu Asp Arg Asn
                  85                  90                  95    
 Asp Gly Thr Phe Leu Met Arg Tyr Arg Met Tyr Glu Thr Val Asp Glu
             100                 105                 110        
 Gly Leu Lys Ile Glu Val Leu Tyr Gly Asp Glu His Val Ala Gln Ser
         115                 120                 125            
 Pro Tyr Ile Leu Lys Gly Pro Val Tyr His Glu Tyr Cys Glu Cys Pro
     130                 135                 140                
 Glu Asp Pro Gln Ala Trp Gln Lys Thr Leu Ser Cys Pro Thr Lys Glu
 145                 150                 155                 160
 Pro Gln Ile Ala Lys Asp Phe Ala Ser Phe Pro Ser Ile Asn Leu Gln
                 165                 170                 175    
 Gln Met Leu Lys Glu Val Pro Lys Arg Phe Gly Asp Glu Arg Gly Ala
             180                 185                 190        
 Ile Val His Tyr Thr Ile Leu Asn Asn His Val Tyr Arg Arg Ser Leu
         195                 200                 205            
 Gly Lys Tyr Thr Asp Phe Lys Met Phe Ser Asp Glu Ile Leu Leu Ser
     210                 215                 220                
 Leu Thr Arg Lys Tyr Lys Tyr Gln Val Asn Val Asp Gly Thr Val Ala
 225                 230                 235                 240
 Ala Tyr Arg Tyr Pro Tyr Leu Met Leu Gly Asp Ser Leu Val Leu Lys
                 245                 250                 255    
 Gln Asp Ser Pro Tyr Tyr Glu His Phe Tyr Met Ala Leu Glu Pro Trp
             260                 265                 270        
 Lys His Tyr Val Pro Ile Lys Arg Asn Leu Ser Asp Leu Leu Glu Lys
         275                 280                 285            
 Val Lys Trp Ala Lys Glu Asn Asp Glu Glu Ala Lys Lys Ile Ala Lys
     290                 295                 300                
 Glu Gly Gln Leu Met Ala Arg Asp Leu Leu Gln Pro His Arg Leu Tyr
 305                 310                 315                 320
 Cys Tyr Tyr Tyr Gln Val Leu Gln Met Arg Thr Ala Thr Ile Asn Arg
                 325                 330                 335    
 Thr Leu Leu Leu Ser Phe Gly Arg Met Asp Arg Ala Ser Phe Thr Ser
             340                 345                 350        
 Gly Leu Lys His Thr Asn Glu Tyr Cys Cys Lys Phe Leu Tyr Pro Glu
         355                 360                 365            
 Leu Cys Cys Cys Ser Cys Leu Glu Pro Arg Thr Ile Pro Thr Ser Pro
     370                 375                 380                
 Ser Arg Ser Tyr Ala Gln Cys His Arg Thr Ala Thr Val Ala Phe Ala
 385                 390                 395                 400
 Gly Ile His Pro Asn Gly Tyr Ser Asp Val Pro Leu Pro Gly Ser Ser
                 405                 410                 415    
 Arg Phe Ser Asn Ser Lys Phe Asn Gln Ala Gln Lys Asn Ile Tyr Asn
             420                 425                 430        
 Tyr Gly Gly Asp Ile Ser Lys Met Gln Met Gly Ile Pro Asp Asp Thr
         435                 440                 445            
 Tyr Tyr Glu Asn Val Tyr Gln Glu Pro Asn Val Thr Arg Leu Thr Pro
     450                 455                 460                
 Asp Ser Thr Tyr Gly Leu
 465                 470



      <210> 1807
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 1807
 Met Ser Glu Val Leu Pro Leu Gln Arg Val Leu Ala Leu Leu Leu Val
   1               5                  10                  15    
 Glu Gln Arg His Phe Pro Gly Leu Gln Pro Arg Asp Gly Leu Arg Pro
              20                  25                  30        
 Val Leu Leu Gly Val Glu Met Asp Leu Pro Asp Leu Gly Gly Arg Arg
          35                  40                  45            
 Ala Asn Tyr Lys Val Val Val Arg Thr Lys His Leu Ala Gln Tyr Leu
      50                  55                  60                
 Ala His Asp Ser Ser Glu Pro Thr Asn Lys Ala His Pro Gly Glu Met
  65                  70                  75                  80
 Pro Gln Ala Gln Leu Leu Gln Leu Thr Leu Ser Gly Glu Gln Phe Glu
                  85                  90                  95    
 Ala Gly Thr Gln His Lys Gly Asp His Gly Arg Glu Glu Leu Thr Gly
             100                 105                 110        
 Arg Thr Ser Ser Leu
         115        



      <210> 1808
      <211> 160
      <212> PRT
      <213> Homo sapiens


      <400> 1808
 Met Ala Phe Ile Leu Arg Leu Phe Trp Leu Lys Pro Pro Ala Glu Arg
   1               5                  10                  15    
 Gln Arg Lys Ala Thr Ser Ser Asp Gly Gln Gly Ser Trp Val Pro Pro
              20                  25                  30        
 Pro Pro Leu Thr Ser Ser Ser Ser Gln Asn Ala Trp Ala Glu Pro Glu
          35                  40                  45            
 Gln His Arg Leu Leu Trp Asn Leu Leu Leu Arg His Glu Glu Asp Leu
      50                  55                  60                
 Asp Ser Lys Ser Ala Lys Gly Ala Arg Leu Glu Leu Asp Leu Asn Gly
  65                  70                  75                  80
 Val Gln Ser Ala Gly Thr His Tyr Arg Leu Ser Pro Thr Arg Cys Pro
                  85                  90                  95    
 Pro Leu Glu Lys Arg Arg Ile Gly Arg Ser Ile Lys Asp Leu Lys Gln
             100                 105                 110        
 Ile Cys His Asn Val Thr Phe Val Asn Ser Gly Trp Ala Ala Pro Leu
         115                 120                 125            
 Phe Pro Ala Gly Gln Glu Cys Asp Phe Thr Val Lys Arg His Val Gln
     130                 135                 140                
 Val Thr Leu Tyr Val Ala Met Pro Ala Thr His Lys Lys Gly Gly Leu
 145                 150                 155                 160





      <210> 1809
      <211> 395
      <212> PRT
      <213> Homo sapiens


      <400> 1809
 Met Ala Ala Arg Leu Ala Trp Arg Ala Phe Ser Ser Arg Ala Phe Leu
   1               5                  10                  15    
 Leu Ala Ala Ser Phe Cys Trp Cys Arg Ser Lys Arg Val Pro Ser Pro
              20                  25                  30        
 Asp Arg Cys Arg Cys Ser Cys Gln Arg Ser Arg Cys His Val Ala Phe
          35                  40                  45            
 Thr Ser Gly Arg Arg Asn Pro Asp Pro Asp Gln Ser Asp Leu Ser Arg
      50                  55                  60                
 Val Ser Asp Ser Gly Ser His Ser Gly Ser Asp Ser His Ser Gly Ala
  65                  70                  75                  80
 Ser Arg Glu Pro Gly Asp Leu Ala Glu Arg Val Glu Val Val Ala Leu
                  85                  90                  95    
 Ser Asp Cys Gln Gln Glu Leu Ser Leu Val Arg Thr Val Thr Arg Gly
             100                 105                 110        
 Pro Arg Ala Phe Leu Ser Arg Glu Glu Ala Gln His Phe Ile Lys Ala
         115                 120                 125            
 Cys Gly Leu Leu Asn Cys Glu Ala Val Leu Gln Leu Leu Thr Cys His
     130                 135                 140                
 Leu Arg Gly Thr Ser Glu Cys Thr Gln Leu Arg Ala Leu Cys Ala Ile
 145                 150                 155                 160
 Ala Ser Leu Gly Ser Ser Asp Leu Leu Pro Gln Glu His Ile Leu Leu
                 165                 170                 175    
 Arg Thr Arg Pro Trp Leu Gln Glu Leu Ser Met Gly Ser Pro Gly Pro
             180                 185                 190        
 Val Thr Asn Lys Ala Thr Lys Val Gly Ser Cys Gly Gly His Thr Pro
         195                 200                 205            
 His Arg Gly Pro Arg Ile Leu Arg His Phe Glu Ala Ser Cys Gly Gln
     210                 215                 220                
 Leu Ser Pro Ala Arg Gly Thr Ser Ala Glu Pro Gly Pro Thr Ala Ala
 225                 230                 235                 240
 Leu Pro Gly Pro Ser Asp Leu Leu Thr Asp Ala Val Pro Leu Pro Gly
                 245                 250                 255    
 Ser Gln Val Phe Leu Gln Pro Leu Ser Ser Thr Pro Val Ser Ser Arg
             260                 265                 270        
 Ser Pro Ala Pro Ser Ser Gly Met Pro Ser Ser Pro Val Pro Thr Pro
         275                 280                 285            
 Pro Pro Asp Ala Ser Pro Ile Pro Ala Pro Gly Asp Pro Ser Glu Ala
     290                 295                 300                
 Glu Ala Arg Leu Ala Glu Ser Arg Arg Trp Arg Pro Glu Arg Ile Pro
 305                 310                 315                 320
 Gly Gly Thr Asp Ser Pro Lys Arg Gly Pro Ser Ser Cys Ala Trp Ser
                 325                 330                 335    
 Arg Asp Ser Leu Phe Ala Gly Met Glu Leu Val Ala Cys Pro Arg Leu
             340                 345                 350        
 Val Gly Ala Gly Ala Ala Ala Gly Glu Ser Cys Pro Asp Ala Pro Arg
         355                 360                 365            
 Ala Pro Gln Thr Ser Ser Gln Arg Thr Ala Ala Lys Glu Pro Pro Gly
     370                 375                 380                
 Ser Glu Pro Ser Ala Phe Ala Phe Leu Asn Ala
 385                 390                 395



      <210> 1810
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 1810
 Met Arg Ala Leu Leu Pro Arg Thr Leu Leu Ser Trp Val Val Gln Ser
   1               5                  10                  15    
 Trp Lys Asn Ser Cys Ser Gly Gln Leu Ser Val Leu Ala Leu Leu Ala
              20                  25                  30        
 Val Gln Val Asp Ser His Pro Leu Arg Gln Ser Gly Lys Ala Ala Gly
          35                  40                  45            
 Leu Glu Gly Arg Gly Pro Gly Thr Phe Gly Thr Gln Leu Val Val Glu
      50                  55                  60                
 Ala Leu Glu Gly Gln Gly Leu Arg Glu Gln Pro Ser Ser Gln Asp Pro
  65                  70                  75                  80
 Gln Ser Pro Asp Gly Arg Asp Trp Ser Pro Gln Asn Leu Ser Ser Ser
                  85                  90                  95    
 Trp Ala Ala Leu Leu Asn Gly Thr Phe Cys Val Asp
             100                 105            



      <210> 1811
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 1811
 Met Leu Leu Lys Ile Arg Ser Glu Gly Val Ser Gln Val Leu Leu Val
   1               5                  10                  15    
 Leu Met Val Leu Gln Glu Leu Leu Glu Leu Asp Ser Lys Val Leu Arg
              20                  25                  30        
 Glu Lys Glu Ala Lys Lys Glu Asp Arg Glu Leu Gln Asp Pro Leu Glu
          35                  40                  45            
 Leu Val Ser Leu Asp Ser Gln
      50                  55



      <210> 1812
      <211> 316
      <212> PRT
      <213> Homo sapiens


      <400> 1812
 Met Arg Lys Glu Trp Ser Leu Met Leu Tyr Asn Ser Leu Ile Cys Ile
   1               5                  10                  15    
 Ile Pro Phe Gly Leu Met Thr Ala Ser Ile Arg Arg Tyr His Thr Cys
              20                  25                  30        
 Ala Thr Asp Gly Glu Pro Asp Ser Ser Val Leu Val Gly Gly Asp Gly
          35                  40                  45            
 Asp Leu Thr Leu Leu Val Ala Ala Leu Gly Leu Asp Leu Gly Leu Pro
      50                  55                  60                
 Phe Met Leu Leu Pro Pro Leu Met Glu Trp Met Arg Val Ala Ile Thr
  65                  70                  75                  80
 Tyr Ala Glu His Arg Arg Ser Leu Thr Val Asp Ser Gly Asp Ile Arg
                  85                  90                  95    
 Gln Ala Ala Arg Leu Leu Leu Pro Gly Leu Asp Cys Glu Pro Arg Gln
             100                 105                 110        
 Leu Lys Leu Asp Ala Arg Ala Ala Thr Glu Lys Phe Asn Gln Asp Leu
         115                 120                 125            
 Gly Phe Arg Met Leu Asn Cys Gly Arg Thr Asp Leu Ile Asn Gln Ala
     130                 135                 140                
 Ile Glu Ala Leu Gly Pro Asp Gly Val Asn Thr Met Asp Asp Gln Gly
 145                 150                 155                 160
 Met Thr Pro Leu Met Tyr Ala Cys Ala Ala Gly Asp Glu Ala Met Val
                 165                 170                 175    
 Gln Met Leu Ile Asp Ala Gly Ala Asn Leu Asp Ile Gln Val Pro Ser
             180                 185                 190        
 Asn Ser Pro Arg His Pro Ser Ile His Pro Asp Ser Arg His Trp Thr
         195                 200                 205            
 Ser Leu Thr Phe Ala Val Leu His Gly His Ile Ser Val Val Gln Leu
     210                 215                 220                
 Leu Leu Asp Ala Gly Ala His Val Glu Gly Ser Ala Val Asn Gly Gly
 225                 230                 235                 240
 Glu Asp Ser Tyr Ala Glu Thr Pro Leu Gln Leu Ala Ser Ala Ala Gly
                 245                 250                 255    
 Asn Tyr Glu Leu Val Ser Leu Leu Leu Ser Arg Gly Ala Asp Pro Leu
             260                 265                 270        
 Leu Ser Met Leu Glu Ala His Gly Met Gly Ser Ser Leu His Glu Asp
         275                 280                 285            
 Met Asn Cys Phe Ser His Ser Ala Ala His Gly His Arg Tyr Leu Pro
     290                 295                 300                
 Gly Ile Pro Thr Leu Cys Asp Met Arg Ala Leu Asn
 305                 310                 315    



      <210> 1813
      <211> 91
      <212> PRT
      <213> Homo sapiens


      <400> 1813
 Met Ala Val Tyr Val Gly Met Leu Arg Leu Gly Arg Leu Cys Ala Gly
   1               5                  10                  15    
 Ser Ser Gly Val Leu Gly Ala Arg Ala Ala Leu Ser Arg Ser Trp Gln
              20                  25                  30        
 Glu Ala Arg Leu Gln Gly Val Arg Phe Leu Arg Thr Pro His Asp Gln
          35                  40                  45            
 Leu Leu Pro Pro Ile Tyr Val Pro Pro Ser Pro Lys Lys Val Asp Gly
      50                  55                  60                
 Leu Val Trp Gly Phe Ser Glu Pro Pro Arg Lys Glu Phe Lys Glu Lys
  65                  70                  75                  80
 Pro Gly Leu Ser Arg Leu Pro Pro Asp Leu Pro
                  85                  90    



      <210> 1814
      <211> 199
      <212> PRT
      <213> Homo sapiens


      <400> 1814
 Met Tyr Leu Lys Leu Cys His Leu Asn Ile Phe Ile Leu Met Val Leu
   1               5                  10                  15    
 Ser Arg Gly Val Arg Val Ala Ile His Thr Leu Ile Val Tyr Leu Ser
              20                  25                  30        
 Val Ser Phe Asn Phe Cys Cys Phe Gln Glu Pro Gln Leu Leu Gly Ile
          35                  40                  45            
 Ala Thr Glu Gly Ala Glu Ser Pro Gln Lys Arg Lys Phe Asp Arg Phe
      50                  55                  60                
 Pro Glu Val Glu Leu Leu Gly Gln Thr Ile Val Leu Ala Ile Thr Ile
  65                  70                  75                  80
 Phe Cys Tyr Leu Thr Leu Ser Tyr Ser Ser Asn Asn Ile Leu Ala Val
                  85                  90                  95    
 Lys His Cys Phe Glu Tyr Phe Ile Ala Phe Tyr Cys Cys Phe Arg Lys
             100                 105                 110        
 Gln Leu Ser Asp Ser Leu Thr Glu His Arg Gly Leu Arg Gly Asn Lys
         115                 120                 125            
 Asn Gly Cys Ala Cys Phe Arg Ile Thr Gln Cys Trp Thr Phe Glu Glu
     130                 135                 140                
 Gly Glu Ala Glu Met Asp Arg Ile Val Val Ala Glu Leu Ser Leu Tyr
 145                 150                 155                 160
 Thr Trp Ser Cys Gly Gly Tyr Leu Leu Phe Phe Gln Leu Arg Val Arg
                 165                 170                 175    
 Arg Asn Gly Met Lys Tyr Ile Phe Asn Ser Leu Ala Gly Lys Lys His
             180                 185                 190        
 His Thr Asp Phe Leu Leu Gln
         195                



      <210> 1815
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 1815
 Met Leu Lys Cys Ala Leu Arg Ala Ala Ser His Ala Leu Lys Gly Met
   1               5                  10                  15    
 Leu Ala Leu Phe His Phe His Leu Pro Pro Trp Asp Asp Ala Val Arg
              20                  25                  30        
 Arg Pro Ser Val Asp Ala Ser Pro Ser Thr Leu Asn Phe Pro Asp Ala
          35                  40                  45            
 Glu Leu
      50



      <210> 1816
      <211> 145
      <212> PRT
      <213> Homo sapiens


      <400> 1816
 Met Glu Ile Pro Leu Met Phe Arg Ser Ser Ala Leu Gln Val Ser Val
   1               5                  10                  15    
 Ser Leu Leu Leu Pro Leu Ser Gln Pro Arg Asp Val Thr Leu Phe Val
              20                  25                  30        
 Ser Leu Phe Gly Val Arg Gly Pro Arg Asn Arg Val Ile Thr Val Ala
          35                  40                  45            
 Arg Thr Thr Gly Lys Leu Leu Asn His Pro Val Gly Ile Thr Glu Pro
      50                  55                  60                
 Ala Gly Ile Lys Trp Ala His Gly Glu Asn Ile Ala Lys Ile Ser Asn
  65                  70                  75                  80
 Glu Val Ser Ala Tyr Glu Val Asn Thr Gly Pro Pro Val Ala Gly Glu
                  85                  90                  95    
 Gly Glu Ser Ser Pro Arg Leu Gln Phe Val Lys Val Asp Lys Ala Tyr
             100                 105                 110        
 Asp Asn Gly Gln Tyr Gln Leu Leu Gly Ile Pro Ser Leu Ser Ser Trp
         115                 120                 125            
 Trp Tyr Trp Ser Phe Pro Thr Gln Asp Phe Arg Gly Phe Gln Gly Tyr
     130                 135                 140                
 Asn
 145



      <210> 1817
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1817
 Met Arg Ala Leu Arg Asp Arg Ala Gly Leu Leu Leu Cys Val Leu Leu
   1               5                  10                  15    
 Leu Ala Ala Leu Leu Glu Ala Ala Leu Gly Leu Pro Val Lys Lys Pro
              20                  25                  30        
 Arg Leu Arg Gly Pro Arg Pro Gly Ser Leu Thr Arg Leu Ala Glu Thr
          35                  40                  45            
 Ile Gln Ser Leu Lys Gly Trp Lys Ser Pro Gln Gly Gly Arg Glu Arg
      50                  55                  60                
 Arg Thr Gly Met Arg Pro Gly Ser Leu Ala Ala Gln Arg Pro Gln Ala
  65                  70                  75                  80
 Ser Leu Gln Pro Leu Arg Ser Gln Ser Gln Val Val Thr Arg Ile Lys
                  85                  90                  95    
 Gly Lys Asp Gly Arg Gly Glu Leu Asn Ile Leu Tyr Ser Val Leu Phe
             100                 105                 110        
 Ile Gln His Ile Gln His Arg Arg Ala Ala Gly Gly Lys Pro Glu Val
         115                 120                 125            
 Ile Tyr Arg Ala Pro Ile Met Tyr Gln Ala Leu Cys Ser Ala Gln Tyr
     130                 135                 140                
 Pro Thr Val Asn Lys Ala Asp Thr Ile Pro Val Cys Thr Glu Leu Thr
 145                 150                 155                 160
 Phe Glu Leu Glu Lys Val Thr Asp Gly Met Glu Ile Ala
                 165                 170            



      <210> 1818
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 1818
 Met Leu Leu Leu Leu Leu Leu Leu Leu Leu Leu Gly Cys Phe His Leu
   1               5                  10                  15    
 Gly Gln Trp Asn Val Arg Glu Arg Trp Gln Leu Arg Cys Lys Ser Ser
              20                  25                  30        
 Ser Asn Thr Ile Cys Gly Gly Thr Glu Leu Lys Tyr Val Glu Ser Gly
          35                  40                  45            
 Lys Asp Leu Cys Tyr Glu Leu Leu Gln Pro Leu Arg Ala Ala Thr Thr
      50                  55                  60                
 Thr Thr Thr Thr Asp Lys Thr Glu His Thr Leu Cys Ala Trp Asn Tyr
  65                  70                  75                  80
 Asp Arg Asp Gly Leu Ile Ser Cys Asn Cys Gln Asn Cys Val Arg Glu
                  85                  90                  95    
 Val Phe Thr Ser Glu Ile Gln Asp Ser Tyr Ser Ser Ser Leu Val Ser
             100                 105                 110        
 Ser Gly Leu Leu Leu Pro Glu Leu Ser Cys Asp Tyr Leu Arg Asp Val
         115                 120                 125            
 Ser Val Ser Ser Glu Val Gln Ser Thr Val Glu Ala Phe Val Ala Glu
     130                 135                 140                
 His Ala Val Ser
 145            



      <210> 1819
      <211> 68
      <212> PRT
      <213> Homo sapiens


      <400> 1819
 Met Val Leu Ala Cys Val Arg Glu Val Leu Tyr Leu Tyr His Tyr Val
   1               5                  10                  15    
 Ile Ile Thr Leu Phe Asp Tyr Cys Gly Phe Lys Gln His Tyr Glu Ala
              20                  25                  30        
 Asn Val Val Val Phe Lys Lys Ser Ala Lys Gly Phe Gln Gly Thr Ala
          35                  40                  45            
 Gly Thr Tyr Val Val Cys Val Ala Val Asp Pro Glu Arg Cys Ser Val
      50                  55                  60                
 Gly Thr Gly Arg
  65            



      <210> 1820
      <211> 278
      <212> PRT
      <213> Homo sapiens


      <400> 1820
 Met Asn Glu Ala Thr Leu Arg Arg Gln Thr Ala Trp Leu Leu Val Pro
   1               5                  10                  15    
 Trp Leu Leu Ala Pro Gln His Val Cys Arg Leu Phe Ser Arg Leu Ala
              20                  25                  30        
 Ala Ser Pro His Ser Leu Thr Phe Leu Ala Val Arg Ser Ser His Val
          35                  40                  45            
 Cys Pro Ala Ser Val Ser Trp Thr Gly Lys Met Leu Ser Leu Asn Pro
      50                  55                  60                
 Ser Thr Pro Gln Val Ile Arg Ser Phe Leu Thr Gln Thr Gln Leu Phe
  65                  70                  75                  80
 Pro Arg Asn Val Arg Pro Ser Pro Gln Gly Ala Gly Ser Glu Tyr Pro
                  85                  90                  95    
 Gly Thr Phe Arg Gly Gly Gly Gly Ser His Thr Pro Ile Pro Tyr Arg
             100                 105                 110        
 Glu Ser Glu Glu Ser Gly Pro Leu Phe Phe Gln Phe Leu Val Asn Asn
         115                 120                 125            
 Lys His Ala Arg Pro Arg Leu Pro Val Gln Thr Pro Gln Gly Gln Leu
     130                 135                 140                
 Gly Leu Arg Gln Ala Pro Arg Ala Asp Arg Arg His Gln Met Ala Ile
 145                 150                 155                 160
 Thr Lys Arg Glu Gly Arg Gly His Pro Arg Arg Arg Ile Thr Leu Ala
                 165                 170                 175    
 Leu Phe Pro Ala Leu Gly Arg Pro Asp Ala Ser Ser Ala Lys Val Ala
             180                 185                 190        
 Leu Gln Trp Leu Glu Ala Ala Thr Asn Asp Phe Leu His Arg Ile Gly
         195                 200                 205            
 Lys Asn Tyr Phe Lys Val His Met Glu Pro Lys Lys Ser Pro His Cys
     210                 215                 220                
 Gln Asp Asn Pro Lys Pro Lys Asn Lys Ala Gly Gly Ile Thr Leu Pro
 225                 230                 235                 240
 Asp Phe Lys Leu Tyr Tyr Lys Ala Thr Val Thr Lys Thr Ala Arg Phe
                 245                 250                 255    
 Leu Leu Tyr Lys Val Ser Gln Ile Asp Asn Thr Asp Leu Phe Asp Pro
             260                 265                 270        
 Val Lys Ile Lys Phe Glu
         275            



      <210> 1821
      <211> 230
      <212> PRT
      <213> Homo sapiens


      <400> 1821
 Met Gly Arg Pro Arg Ser Ala Gly Arg Gly Ala Trp Glu Gly Ala Gly
   1               5                  10                  15    
 Pro Gly Gly Glu Phe Gly Val Ser Leu Cys Leu Leu Gln Leu Ala Ser
              20                  25                  30        
 Cys Ile His Phe Trp Leu Val Leu Ser Ile Phe Leu Arg Thr Leu Ser
          35                  40                  45            
 Lys Lys Gln Leu His Ala Ile Asp Ile Gln Thr Glu Gln Gly Pro Leu
      50                  55                  60                
 Ala Leu Glu Gly Val Gly Ala Leu Asn Ile Leu Lys Val Thr Ser Trp
  65                  70                  75                  80
 Ser Gly Arg Pro Leu Trp Ser Pro Tyr Leu Cys Val Ala Leu Ser Trp
                  85                  90                  95    
 Arg Ile Cys Gln Gly Asp Ala Leu Gln Gln Pro Glu Asp Cys Trp Val
             100                 105                 110        
 Lys Gly Ser Val Ala Gly Asp Leu Thr Gln Gln Gly Leu Ser Tyr Leu
         115                 120                 125            
 Pro Glu Val Val Ser Arg Asn Gly Arg Ala Ala Phe Arg Leu Thr Ser
     130                 135                 140                
 Leu Glu Leu Pro Pro Pro Gln Thr Arg Pro Gly Ala Glu Ser Pro Arg
 145                 150                 155                 160
 Met Leu Ser Leu Val Lys Ser Glu Val Cys Val Ile Gly Gly Phe Ile
                 165                 170                 175    
 Pro Gly Lys Ser Ser Val Tyr Glu Thr Asn Ile His Gly Val Cys Ile
             180                 185                 190        
 Thr Val Gly Val Arg Cys Glu Pro Gly Gly Gln Val Ser Gly Ala Trp
         195                 200                 205            
 Gly Asn Cys Trp Pro Pro Ser Ser Val Gln Cys His Ser Arg Ser Leu
     210                 215                 220                
 Val Leu Trp Gly His Pro
 225                 230



      <210> 1822
      <211> 166
      <212> PRT
      <213> Homo sapiens


      <400> 1822
 Met Glu Ser Cys Phe Leu Leu Trp Leu Ala Gln Met Leu Val Glu Ser
   1               5                  10                  15    
 Ser His Ala Ala Arg Val His Ser Ser Leu Gln Arg Gln His Arg Arg
              20                  25                  30        
 Arg Met Arg Val His Leu Tyr Arg Glu Ser Ala Gln Val Thr Gln His
          35                  40                  45            
 Trp Leu Arg Val Pro Thr Ala Ala Lys Gln Leu His Gln Asp Ala Glu
      50                  55                  60                
 Arg Thr Thr Val Thr Gln Tyr Ser Thr Cys Ala Leu Leu Thr Ala Leu
  65                  70                  75                  80
 Cys Leu Leu Leu Pro Val Leu Gln Glu Thr Ala Gln Ser Arg Arg Met
                  85                  90                  95    
 Val Thr Ser His Pro Glu Asp Ser Pro Ala Leu Ala Arg Lys His Gly
             100                 105                 110        
 Ala Ser Gln Pro Ala Gly Leu Gly Phe Pro Arg Thr Gln Thr Val Thr
         115                 120                 125            
 Pro Ala Phe Thr Phe Gln Asn Pro Thr Ala Ala Glu Pro Ala Leu Leu
     130                 135                 140                
 Ser Ala Trp Leu Gly Arg Ala Pro Glu Thr Glu Thr Ile Thr Asp Met
 145                 150                 155                 160
 Ala Gly Ala Ser Gly Leu
                 165    



      <210> 1823
      <211> 165
      <212> PRT
      <213> Homo sapiens


      <400> 1823
 Met Lys Lys Leu His Ser Gly Arg Thr Pro Phe Val Thr Thr Val Ser
   1               5                  10                  15    
 Phe Leu Pro Ala Cys Pro Val Ala Cys Ile Leu Leu Val Trp Asn Ser
              20                  25                  30        
 Gln Thr Pro Ala Gly Leu Gln Ser Leu Cys Thr Gly Arg His Pro Ser
          35                  40                  45            
 Leu Ser Ala Arg Ala Gln Trp Ala Gly Pro Arg Ala Ser Arg Glu Glu
      50                  55                  60                
 Gly Thr Phe Trp Thr Glu Pro Val Gly Gln Glu Arg Arg Leu Ile Arg
  65                  70                  75                  80
 Ser Gly Ser Ser Gln Asn Glu Ser Gln Glu Asp Gln Gly Ala Asp Leu
                  85                  90                  95    
 Ile Ser His Glu Gly Leu Lys Ala Asp Asn Arg Arg Glu Ser Ser Thr
             100                 105                 110        
 Trp Ala Asn Glu Val Glu Asp Arg Arg Pro Gln Cys Thr Ser Ala Leu
         115                 120                 125            
 Asn Leu Thr Pro Ser His Leu His Pro Pro His Pro Leu Thr Thr Phe
     130                 135                 140                
 Phe Arg Asn Val Ile Gly Ile Lys Ile Pro Pro Gly Leu Val Ala Met
 145                 150                 155                 160
 Gly Gly Thr Val Ala
                 165



      <210> 1824
      <211> 124
      <212> PRT
      <213> Homo sapiens


      <400> 1824
 Met Leu Val Ser Pro Ala Pro Val Pro Leu Pro Leu Leu Ala Gln Ala
   1               5                  10                  15    
 Ala Ala Gly Pro Ala Leu Leu Pro Ser Pro Gly Pro Ala Ala Ser Gly
              20                  25                  30        
 Ala Ser Ala Lys Ala Pro Val Arg Ser Val Val Thr Glu Thr Val Ser
          35                  40                  45            
 Thr Tyr Val Ile Arg Asp Glu Trp Gly Asn Gln Ile Trp Ile Cys Pro
      50                  55                  60                
 Gly Cys Asn Lys Pro Asp Asp Gly Ser Pro Met Ile Gly Cys Asp Asp
  65                  70                  75                  80
 Cys Asp Asp Trp Tyr His Trp Pro Cys Val Gly Ile Met Thr Ala Pro
                  85                  90                  95    
 Pro Glu Glu Met Gln Trp Phe Cys Pro Lys Cys Ala Asn Lys Lys Lys
             100                 105                 110        
 Asp Lys Lys His Lys Lys Arg Lys His Arg Ala His
         115                 120                



      <210> 1825
      <211> 217
      <212> PRT
      <213> Homo sapiens


      <400> 1825
 Met Ala Val Phe Leu Gln Leu Leu Pro Leu Leu Leu Ser Arg Ala Gln
   1               5                  10                  15    
 Gly Asn Pro Gly Ala Ser Leu Asp Gly Arg Pro Gly Asp Arg Val Asn
              20                  25                  30        
 Leu Ser Cys Gly Gly Val Ser His Pro Ile Arg Trp Val Trp Ala Pro
          35                  40                  45            
 Ser Phe Pro Ala Cys Lys Gly Leu Ser Lys Gly Arg Arg Pro Ile Leu
      50                  55                  60                
 Trp Ala Ser Ser Ser Gly Thr Pro Thr Val Pro Pro Leu Gln Pro Phe
  65                  70                  75                  80
 Val Gly Arg Leu Arg Ser Leu Asp Ser Gly Ile Arg Arg Leu Glu Leu
                  85                  90                  95    
 Leu Leu Ser Ala Gly Asp Ser Gly Thr Phe Phe Cys Lys Gly Arg His
             100                 105                 110        
 Glu Asp Glu Ser Arg Thr Val Leu His Val Leu Gly Asp Arg Thr Tyr
         115                 120                 125            
 Cys Lys Ala Pro Gly Pro Thr His Gly Ala Cys Pro Arg Asn Arg Phe
     130                 135                 140                
 Asp His Ser Leu Asp Leu Leu Cys Pro Pro His Ile Ala Pro Leu Val
 145                 150                 155                 160
 Lys Thr Glu Pro Gln Arg Pro Val Lys Glu Glu Glu Pro Lys Ile Pro
                 165                 170                 175    
 Gly Asp Leu Asp Gln Glu Pro Ser Leu Leu Tyr Ala Asp Leu Asp His
             180                 185                 190        
 Leu Ala Leu Ser Arg Pro Arg Arg Leu Ser Thr Ala Asp Pro Ala Asp
         195                 200                 205            
 Ala Ser Thr Ile Tyr Ala Val Val Val
     210                 215        



      <210> 1826
      <211> 161
      <212> PRT
      <213> Homo sapiens


      <400> 1826
 Met Lys Leu Leu Ala Tyr Phe Gly Cys Gly Thr Leu Met Trp Ala Ala
   1               5                  10                  15    
 Glu Phe Ala Gly Tyr Ile Glu Arg Pro Gln Leu Ile Arg Ala Lys Val
              20                  25                  30        
 Pro Ile Val Lys Phe Arg Asp Lys Val Arg Lys Arg Leu Ile Val His
          35                  40                  45            
 Ile Ser Asp Phe Glu Gly Asn Val Arg Tyr His Gly Thr Val Ser Glu
      50                  55                  60                
 Lys Asn Asp Gly Ile Trp Gln Lys Glu Ser Phe Ser Pro Ala Ile Gln
  65                  70                  75                  80
 Leu His Leu Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu Ser
                  85                  90                  95    
 Lys Asn Glu Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys Tyr
             100                 105                 110        
 Tyr Ala Thr Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg Glu
         115                 120                 125            
 Ala Lys Ala Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys Tyr
     130                 135                 140                
 Ile Cys Val Glu Gly Ser Phe Leu Phe Thr Ile Tyr Val Ser Ser Trp
 145                 150                 155                 160
 Tyr
    



      <210> 1827
      <211> 132
      <212> PRT
      <213> Homo sapiens


      <400> 1827
 Met Leu His Thr Leu Glu Leu Leu Phe Leu Leu Lys Ile Ser Pro Leu
   1               5                  10                  15    
 Leu Ser Phe Phe Phe Leu Gln Leu Val Glu Phe Phe Pro Asp Lys Asp
              20                  25                  30        
 Lys Phe Pro Asn Thr Ala Thr Pro Ser Leu Phe Trp His Val Gln Ser
          35                  40                  45            
 Pro Gly Gln Gly Leu Gln Leu Leu Leu Lys Tyr Phe Ser Gly Asp Thr
      50                  55                  60                
 Leu Val Gln Gly Ile Glu Gly Phe Glu Ala Glu Phe Lys Arg Ser Gln
  65                  70                  75                  80
 Ser Ser Phe Asn Leu Arg Arg Pro Ser Val His Trp Ser Asp Ala Ala
                  85                  90                  95    
 Glu Tyr Phe Cys Ala Ala Gly Lys Leu Glu Val Val Glu Gly Ile Asp
             100                 105                 110        
 Leu Leu Thr Leu Ser Ser Lys Phe Thr Pro Cys Leu Phe Cys Glu Gly
         115                 120                 125            
 Pro Glu Asp Leu
     130        



      <210> 1828
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1828
 Met Ala Leu Leu Gln Leu His Ala Val Gly Gly Val Ala Leu Thr Ser
   1               5                  10                  15    
 Ser His Pro Ser Met Trp Ala Thr Gly Glu Glu Leu Arg Lys Pro Pro
              20                  25                  30        
 Trp Gln Gly Ser Ala Gly Ser Ala Ser Gly Val Glu Glu Leu Thr Gly
          35                  40                  45            
 Lys His Ser Cys Pro Gly Pro Glu Glu Pro Ala Thr Val Gln Lys Ala
      50                  55                  60                
 Pro Ala
  65    



      <210> 1829
      <211> 152
      <212> PRT
      <213> Homo sapiens


      <400> 1829
 Met Leu Ala Pro Cys Ser Gly Trp Glu Leu Gly Cys Phe Arg Leu Cys
   1               5                  10                  15    
 Leu Arg Gln Val Arg Leu Trp Ala Gly Ala Gly Arg Trp Ala Cys Trp
              20                  25                  30        
 Ala Cys Gln Ala Arg Pro Tyr Ser Ser Gly Gly Ser Glu Arg Trp Pro
          35                  40                  45            
 Gly Ser Glu Thr Glu Val Pro Pro Pro Gly Pro Ala Arg Arg Thr Leu
      50                  55                  60                
 Lys Glu Trp Thr Leu Gln Val Ser Pro Phe Gly Arg Leu Arg Ala Arg
  65                  70                  75                  80
 Leu Pro Cys His Leu Ala Val Arg Pro Leu Asp Pro Leu Thr Tyr Pro
                  85                  90                  95    
 Asp Gly Asp Arg Val Leu Val Ala Val Cys Gly Val Glu Gly Gly Val
             100                 105                 110        
 Arg Gly Leu Asp Gly Leu Gln Val Lys Tyr Asp Glu Asp Leu Glu Glu
         115                 120                 125            
 Met Ala Ile Val Ser Asp Thr Ile His Pro Gln Ala Ser Val Glu Val
     130                 135                 140                
 Asn Ala Pro Leu Lys Phe Gly Lys
 145                 150        



      <210> 1830
      <211> 460
      <212> PRT
      <213> Homo sapiens


      <400> 1830
 Met Ser Glu Val Arg Met Val Met Leu Thr Cys Val Cys Phe Ser Phe
   1               5                  10                  15    
 Leu Leu Gly Arg Met Gly Asp Tyr Thr Ser Glu Leu Gln Asn Val Asn
              20                  25                  30        
 Asn Trp Trp Gln Ala Ala Gln Arg Arg Pro Phe Lys Pro Phe Ala Pro
          35                  40                  45            
 Glu Trp Thr Ala Gly Ile Ala Cys His His Pro Thr Leu Ala Met Ile
      50                  55                  60                
 Gly Tyr Phe Ala Glu Ala Gly Gly Gly Thr Ser Gly Arg Thr Gly Ser
  65                  70                  75                  80
 Val Cys Gln Gly Met Glu Leu Ser Cys Pro Gly Ser Arg Cys Pro Val
                  85                  90                  95    
 Gln Glu Gln Arg Ala Arg Trp Glu Arg Lys Arg Ala Cys Thr Ala Arg
             100                 105                 110        
 Glu Leu Leu Glu Thr Glu Arg Arg Tyr Gln Glu Gln Leu Gly Leu Val
         115                 120                 125            
 Ala Thr Tyr Phe Leu Gly Ile Leu Lys Ala Lys Gly Thr Leu Arg Pro
     130                 135                 140                
 Pro Glu Arg Gln Ala Leu Phe Gly Ser Trp Glu Leu Ile Tyr Gly Ala
 145                 150                 155                 160
 Ser Gln Glu Leu Leu Pro Tyr Leu Glu Gly Gly Cys Trp Gly Gln Gly
                 165                 170                 175    
 Leu Glu Gly Phe Cys Arg His Leu Glu Leu Tyr Asn Gln Phe Ala Ala
             180                 185                 190        
 Asn Ser Glu Arg Ser Gln Thr Thr Leu Gln Glu Gln Leu Lys Lys Asn
         195                 200                 205            
 Lys Gly Phe Arg Arg Phe Val Arg Leu Gln Glu Gly Arg Pro Glu Phe
     210                 215                 220                
 Gly Gly Leu Gln Leu Gln Asp Leu Leu Pro Leu Pro Leu Gln Arg Leu
 225                 230                 235                 240
 Gln Gln Tyr Glu Asn Leu Val Val Ala Leu Ala Glu Asn Thr Gly Pro
                 245                 250                 255    
 Asn Ser Pro Asp His Gln Gln Leu Thr Leu Ser Leu Leu Leu Cys Leu
             260                 265                 270        
 Phe Phe Lys Lys Ser Asp Pro Asp Pro Gly Pro Phe Gln Asn Asn Leu
         275                 280                 285            
 Phe His Asn His Gly Thr Gln Ser Gln Ser Cys Met Gly Ser Lys Val
     290                 295                 300                
 Gly Asp Val Ile Pro Gly Ala Ala Arg Leu Ile Ser Glu Thr Ala Gln
 305                 310                 315                 320
 Arg Val His Thr Ile Gly Gln Lys Gln Lys Asn Asp Gln His Leu Arg
                 325                 330                 335    
 Arg Val Gln Ala Leu Leu Ser Gly Arg Gln Ala Lys Gly Leu Thr Ser
             340                 345                 350        
 Gly Arg Trp Phe Leu Arg Gln Gly Trp Leu Leu Val Val Pro Pro His
         355                 360                 365            
 Gly Glu Pro Arg Pro Arg Met Phe Phe Leu Phe Thr Asp Val Leu Leu
     370                 375                 380                
 Met Ala Lys Pro Arg Pro Pro Leu His Leu Leu Arg Ser Gly Thr Phe
 385                 390                 395                 400
 Ala Cys Lys Ala Leu Tyr Pro Met Ala Gln Cys His Leu Ser Arg Val
                 405                 410                 415    
 Phe Gly His Ser Gly Gly Pro Cys Gly Gly Leu Leu Ser Gln Pro Glu
             420                 425                 430        
 Lys Leu Glu Glu Ser Tyr Arg Phe Gln Asn Ser Gly Tyr Leu Arg Asp
         435                 440                 445            
 Arg Ser Gln Pro Arg Val Gln Arg Asn Leu Gln Tyr
     450                 455                 460



      <210> 1831
      <211> 306
      <212> PRT
      <213> Homo sapiens


      <400> 1831
 Met Leu Leu Ser Leu Leu Gly Ala Cys Ala Val Val Gly Pro Phe His
   1               5                  10                  15    
 Gly Pro Glu Trp Glu Pro Val Gln Gly Leu Leu Ser Gln Asn His Ser
              20                  25                  30        
 Cys Arg Asp Pro Gln Cys Cys Gly Asn Leu Leu Val Leu Cys Leu Phe
          35                  40                  45            
 Leu Val Trp Gln Val Arg His Cys Trp His Gln Val Thr Arg Thr Arg
      50                  55                  60                
 Phe Ser Thr Arg Asn Val Ile Lys Ala His Met Gly Glu Asn Gln Glu
  65                  70                  75                  80
 Gln Leu Arg Cys Lys Ile Asp Ala Glu Thr Gln Thr Pro Glu Trp Glu
                  85                  90                  95    
 Asn Gln Asp Lys Asn Gly Ser Glu Asp Ala Val Glu Thr Gln Thr Phe
             100                 105                 110        
 Glu Lys Lys Asp Lys Lys Glu Ala Gly Glu Glu Asp Gly Glu Glu Ile
         115                 120                 125            
 Gln Ala Gln Gly Leu Gly Lys Gln Gly Gln Thr Gly Asp Glu Asn Gly
     130                 135                 140                
 Glu Glu Thr Gln Thr Pro Gln Trp Glu Lys Gln Asp Gln Met Lys Gly
 145                 150                 155                 160
 Asp Ala Asp Val Glu Ile Gln Met Glu Glu Gly Arg Asn Lys Asp Gln
                 165                 170                 175    
 Val Gly Gly Gln Asp Ala Ala Gln Thr Gln Ser Cys Gly Arg Glu Asn
             180                 185                 190        
 Val Gly Glu Val Lys Lys Glu Asn Ser Val Glu Thr Gln Ala Leu Asp
         195                 200                 205            
 Trp Gly Lys Gln Glu Cys Val Gly Asn Gly Asn Val Thr Glu Ile Gln
     210                 215                 220                
 Thr Pro Arg Trp Glu Lys His Asp Gln Gly Gly Ser Lys Lys Ala Lys
 225                 230                 235                 240
 Lys Thr Gln Ala Ser Gly Gly Glu Asn Gln Lys Gln Leu Ser His Glu
                 245                 250                 255    
 Ile Gln Val Gly Trp Gly Asn Lys Gly Leu Arg Arg Asp Glu Asp Ala
             260                 265                 270        
 Lys Glu Thr Gln Ile Ala Thr Lys Lys Lys Leu Arg Glu Ile Arg Glu
         275                 280                 285            
 Gly Leu Gly Gly Asp Pro Gly Thr Met Val Gly Lys Pro Glu Thr Ser
     290                 295                 300                
 Ser Lys
 305    



      <210> 1832
      <211> 445
      <212> PRT
      <213> Homo sapiens


      <400> 1832
 Met Val Val Leu Val Trp Pro Phe Leu Met Leu Cys Val Pro Phe Cys
   1               5                  10                  15    
 Leu His Ala Cys Leu Thr Ser Leu Cys Ile Phe Arg Ala Trp Asp Lys
              20                  25                  30        
 Cys Leu Ala Phe Ser Lys Arg Pro Ile Asn Ile His Thr Asp Met Asp
          35                  40                  45            
 Phe Gln Lys Leu Leu Ile Trp Lys Ser Glu Asp Ser Asn Ala Tyr Leu
      50                  55                  60                
 Lys Thr Ile Val Lys Ile Lys Arg Asp Glu Val Gly Glu Glu Pro Ser
  65                  70                  75                  80
 Trp Gln His Gly Met Leu Cys Val Leu Leu Gln Trp Pro Cys Cys Trp
                  85                  90                  95    
 Lys Val Val Ala Glu Ser Ser Ala Asp Gln His Leu Pro Ser Gly Lys
             100                 105                 110        
 Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His
         115                 120                 125            
 Gln Val Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
     130                 135                 140                
 Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser
 145                 150                 155                 160
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Pro Ile Arg
                 165                 170                 175    
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
             180                 185                 190        
 Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Thr
         195                 200                 205            
 Ser Thr Ser His Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys
     210                 215                 220                
 Leu Arg Pro Ala Pro Pro Ile Arg Gln Thr Gln Thr Ser Thr Cys His
 225                 230                 235                 240
 Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
                 245                 250                 255    
 Pro Ala Ile Arg Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser
             260                 265                 270        
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Pro Ile Arg
         275                 280                 285            
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
     290                 295                 300                
 Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg Gln Thr Gln Ser
 305                 310                 315                 320
 Ser Thr Ser His Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys
                 325                 330                 335    
 Leu Arg Pro Ala Pro Pro Ile Arg Gln Thr Gln Thr Ser Thr Cys His
             340                 345                 350        
 Gln Ala Asn Ser Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala
         355                 360                 365            
 Pro Ala Ile Trp Leu Thr Gln Thr Ser Thr Ser His Gln Ala Asn Ser
     370                 375                 380                
 Asp Gln His Leu Pro Ser Gly Lys Leu Arg Pro Ala Pro Ala Ile Arg
 385                 390                 395                 400
 Gln Thr Gln Thr Ser Thr Cys His Gln Ala Asn Ser Asp Gln His Leu
                 405                 410                 415    
 Pro Ser Gly Lys Leu Ile Gln Gln Leu Thr Val Thr Gly Thr Arg Gly
             420                 425                 430        
 Thr Thr Pro Ala Leu Val Gln Arg Arg Ala Gly Glu Glu
         435                 440                 445



      <210> 1833
      <211> 316
      <212> PRT
      <213> Homo sapiens


      <400> 1833
 Met Ser Gly Leu Ala Leu Arg Ala Met Tyr Ser Phe Leu Leu Asp Phe
   1               5                  10                  15    
 Met Glu Ala His Ser Lys Arg Trp Lys Lys Thr Arg Ser Gly Asn Gln
              20                  25                  30        
 Glu Trp Val Pro Glu Gly Lys Pro Glu Leu Gln Val Leu Arg Pro Ser
          35                  40                  45            
 Pro Lys Ala Gln Glu His Leu Arg Gln Gln Arg Ala Ser Ala Arg Gln
      50                  55                  60                
 Gln Lys Gln Glu Glu Arg Arg Pro Ala Glu Asp Thr Tyr Pro Leu Lys
  65                  70                  75                  80
 Ala Glu Arg Glu Ala Val Arg Pro Ser Lys Ser Leu Thr Ile Val Met
                  85                  90                  95    
 Arg Lys Val Lys Val Lys Lys Gln Ala Glu Phe Gln Met Leu Ala Ser
             100                 105                 110        
 Ala Ile Arg Gly Ser Val Gly Pro Arg Gly Ser Ser Ser Thr Gln Lys
         115                 120                 125            
 Pro Pro Ser Asn Pro Pro Pro Leu Gly Ala Cys Phe Lys Cys Gly Asn
     130                 135                 140                
 Glu Gly His Trp Ser Arg Gln Cys Pro Asn Pro Asp Leu Gln Asp Ala
 145                 150                 155                 160
 Val Phe Thr Ile Pro Leu His Pro Asp Ser Gln Asn Leu Phe Val Phe
                 165                 170                 175    
 Thr Trp Glu Asn Pro Asp Thr His Leu Ser His Gln Leu Thr Trp Cys
             180                 185                 190        
 Ile Leu Thr Gln Gly Phe Arg Asp Ser Pro His Leu Phe Gly Gln Ala
         195                 200                 205            
 Leu Ala Arg Asp Leu Cys Thr Leu Ser Leu Lys Pro Ser Thr Leu Leu
     210                 215                 220                
 Gln Tyr Val Asp Asp Leu His Leu Cys Arg Pro Ser Gln Arg Asp Cys
 225                 230                 235                 240
 Asn Val His Thr Ile Ser Leu Leu Asn Phe Leu Ala Glu Trp Gly His
                 245                 250                 255    
 Gln Val Ser Pro Lys Lys Ala Gln Ile Ser Thr Pro Pro Val Thr Tyr
             260                 265                 270        
 Leu Gly Leu Ala Leu Thr Pro Gln Thr Arg Gly Leu Thr Thr Asp Gly
         275                 280                 285            
 Ile Ser Leu Leu Gln Ser Leu Pro Pro Pro Gln Thr Lys Gln Glu Ile
     290                 295                 300                
 Ile Ser Phe Leu Gly Leu Ala Gly Tyr Phe Arg Leu
 305                 310                 315    



      <210> 1834
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1834
 Met Ala Phe Asn Leu Gly Pro Val Gly Gln Ser Ser Ala Ser Gln Arg
   1               5                  10                  15    
 Pro Leu Gln Ala Leu Pro His Leu Met Phe Leu Leu Ala Leu His Leu
              20                  25                  30        
 Gln Pro Ser Thr Ala Ala Leu Thr Ala Gln Tyr Gly Arg Asn Leu Arg
          35                  40                  45            
 Trp Ala Arg Ser Ser Ser Ile Leu Cys Leu Ser Ser Ser Asn Phe Leu
      50                  55                  60                
 Arg Ser Cys Ala Arg Ser Gly Gly Ser Gly Ser Cys Gln Glu Thr Glu
  65                  70                  75                  80
 Pro Thr Ala Gly Gln Ala Glu Ser Lys Gly Lys Ala Lys Val Gly Asp
                  85                  90                  95    
 Ala Gly Thr Pro Ser Leu Glu Met Lys Pro
             100                 105    



      <210> 1835
      <211> 92
      <212> PRT
      <213> Homo sapiens


      <400> 1835
 Met Ala Gly Leu Arg Arg Pro Gln Pro Gly Cys Tyr Cys Arg Thr Ala
   1               5                  10                  15    
 Ala Ala Val Asn Leu Leu Leu Gly Val Phe Gln Glu Leu Cys Met Ala
              20                  25                  30        
 Glu Ala Lys Leu Leu Met Gly Arg Pro Pro Asn Thr Ala Ala Gln Phe
          35                  40                  45            
 Met Val Leu Ser Phe Asn Ser Pro Gly Leu Val Val Asp Ser Ser Met
      50                  55                  60                
 Arg Leu Phe Thr Gly Val Phe Leu Phe His Ser Cys Thr Ile Leu Arg
  65                  70                  75                  80
 Asp Val Ser Leu Ala Ile Val Val Gly Pro Ala Leu
                  85                  90        



      <210> 1836
      <211> 100
      <212> PRT
      <213> Homo sapiens


      <400> 1836
 Met Leu Trp Pro Asp Pro Leu Ser Trp Cys Phe Leu Gly Arg Cys Pro
   1               5                  10                  15    
 Val Ser Leu Asn Val Gln Cys Leu Trp Val Asp Glu Ser Arg Ser Pro
              20                  25                  30        
 Thr Glu Thr Lys Arg Leu Ser Gly Pro Leu Leu Glu Ser Phe Leu Leu
          35                  40                  45            
 Glu Pro Leu Arg Tyr Leu Met Ser Leu Gly Gly Lys Glu Lys Leu Gln
      50                  55                  60                
 Val Arg Met Leu Pro Gly Ala Gln Leu Val Leu Lys Tyr Ile Glu Tyr
  65                  70                  75                  80
 Asn Leu Glu Ile Pro His Val Ser Met Gln Glu Gln Tyr Ser Ile Asn
                  85                  90                  95    
 Gln Leu Ala Trp
             100



      <210> 1837
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1837
 Met Thr Leu Thr Leu Gly Leu Ser Gly Val Met Thr Leu Gln Pro Phe
   1               5                  10                  15    
 Val Trp Ala Trp Trp Gly Glu Lys Gly Ile Gln Gly Cys Glu Asp Ala
              20                  25                  30        
 Gly Ala Ile Gly Phe Gln Gly Arg Met Arg Phe Ser Ser Ser Ser Val
          35                  40                  45            
 Cys Lys Val Val Thr Gly Cys Ser Ser Leu Gly Pro Gly Asp Leu Gly
      50                  55                  60                
 Arg Ser Ser Met Asn Phe Leu Ser Gly Ala Met Gln Leu Tyr Gly Leu
  65                  70                  75                  80
 Gln Ala Ala Arg Tyr Ile Gly Leu Arg Val Cys Glu Asp Cys Gly Thr
                  85                  90                  95    
 Leu Ile
        



      <210> 1838
      <211> 129
      <212> PRT
      <213> Homo sapiens


      <400> 1838
 Met Thr Pro Lys His Asp His Leu Gly His Val Leu Pro Ile Ser Leu
   1               5                  10                  15    
 Gln Leu Leu Leu Glu Leu Ser Ser Cys Leu Pro Ala Ala Ser Ala Val
              20                  25                  30        
 Trp Cys Ala Gly Cys Asn Asp Pro Trp Val Thr Gly Tyr Pro Asp Asn
          35                  40                  45            
 Met His Tyr Asn Tyr Lys Pro Met Leu His Asp Arg Gly Gly Ser Ala
      50                  55                  60                
 Val Thr Leu Ser Ala Ser Gln Ser Trp Tyr Ala Gly Cys Asn Ala Glu
  65                  70                  75                  80
 Lys Ser Glu Val Asn Ala Phe Pro Gly Thr Gln Gly Met Arg Phe Ile
                  85                  90                  95    
 Ser Ala Ala Ser Tyr Lys Asp Trp Val Gln Val Leu Gln Gln Lys Asp
             100                 105                 110        
 Val Ser Arg Asn Met Gly Thr Lys Ala Arg Ser Ala Ser Ser Leu Lys
         115                 120                 125            
 Asn
    



      <210> 1839
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 1839
 Met Leu Pro Gly Leu Ala Leu Leu Leu Leu Ala Ala Trp Thr Ala Arg
   1               5                  10                  15    
 Ala Leu Glu Ser Leu Glu Asn Arg Ser Ala Ala Gly Gly Cys Arg Lys
              20                  25                  30        
 Glu Met Asn Lys Gly Asn Asp Asn Gly Ala Leu Ala Ile Gly Gly Asn
          35                  40                  45            
 Met Val Ile Ile Trp Val Asp Asp Phe Gly Trp Tyr Val Asp Arg Gly
      50                  55                  60                
 Leu Leu Ile Cys Gly Lys Ala Leu Leu Thr Lys Glu Ile Ser Thr Leu
  65                  70                  75                  80
 Lys Leu Ser Met Pro Cys Val Ser Leu Tyr Ser Asp Glu Asn Asp
                  85                  90                  95



      <210> 1840
      <211> 226
      <212> PRT
      <213> Homo sapiens


      <400> 1840
 Met Thr Phe Lys Val Leu Ser Ser Thr Trp Gly Phe Met Ile Leu Phe
   1               5                  10                  15    
 Leu Leu Cys Ile Tyr Ala Gly Ile Glu Glu Ser His Ser Leu Asn Ile
              20                  25                  30        
 His Ile Met Gln Ala Ile Ser Ala Met Ser Gln Arg Gln Tyr Val Thr
          35                  40                  45            
 Leu Thr Phe Ile Asn Cys Pro Arg Asn Glu Leu His Gly Cys Ile Ser
      50                  55                  60                
 Val Gly Thr Gln Ala Ser Pro Gly Tyr Leu Ser Cys Ser Cys Arg Leu
  65                  70                  75                  80
 Pro Pro Gly Leu Arg Arg Gly Ala Pro Asp Pro Gly Ile Val Arg Leu
                  85                  90                  95    
 Arg Pro Ala Lys Glu Gly Pro Ala Gly Gly Ala Pro Ala Gly Val Ser
             100                 105                 110        
 Cys Leu Ala Ala Gly Arg Gly Asp Leu Glu Asp Arg Gly Lys Gly Ser
         115                 120                 125            
 Arg Arg Leu Gly Arg Val His Pro Ala Gln Ala Val Pro Arg Asp Leu
     130                 135                 140                
 Val Trp Gly Asp Asn Pro Trp Arg Asp Val Val Ala Phe Tyr Leu Arg
 145                 150                 155                 160
 Val Glu Leu Lys Met Asp Lys Gln Gly Gly Leu Pro Met Ile His Ile
                 165                 170                 175    
 Tyr Met Lys Gln Ile Gln Ser Leu Gln Leu Lys Ile Lys Tyr Leu Asn
             180                 185                 190        
 Trp Asp Gln Ser Cys His Pro Glu Ile Arg Ile Cys Ser Ser Glu Val
         195                 200                 205            
 Lys Gln Asp Asn Phe Val Val Asn Leu Lys Gly Arg Thr Leu Ile Gly
     210                 215                 220                
 Glu Asn
 225    



      <210> 1841
      <211> 171
      <212> PRT
      <213> Homo sapiens


      <400> 1841
 Met Lys Val Thr Ser Leu Gly Leu Cys Ser Phe Tyr Cys Ala Val Pro
   1               5                  10                  15    
 Thr Glu Thr Thr Tyr His Thr Leu Glu Glu Gly Val Val Glu Tyr Cys
              20                  25                  30        
 Thr Ala Glu Ala Pro Pro Pro Leu Pro Pro Glu Thr Pro Val Asp Met
          35                  40                  45            
 Met Ala Gln His Ala Asp Thr Ser Val Lys Pro Gln Ala Leu Lys Ser
      50                  55                  60                
 Arg Ile Ala Leu Asn Ser Ala Lys Leu Ile Gln Glu Gln Arg Val Thr
  65                  70                  75                  80
 Asn Leu His Val Lys Glu Ile Ala Gln His Leu Glu Gln Gln Asn Asp
                  85                  90                  95    
 Leu Leu Gln Met Ile Arg Arg Ser Gln Glu Val Gln Ala Cys Ala Gln
             100                 105                 110        
 Glu Arg Gln Ala Gln Ala Met Glu Gly Thr Gln Ala Ala Leu Ser Val
         115                 120                 125            
 Leu Ile Gln Val Leu Arg Pro Met Ile Lys Asp Phe Arg Arg Tyr Leu
     130                 135                 140                
 Gln Ser Asn Thr Ala Asn Pro Ala Pro Ala Ser Asp Pro Gly Gln Val
 145                 150                 155                 160
 Ala Gln Asn Gly Gln Pro Asp Ser Ile Ile Gln
                 165                 170    



      <210> 1842
      <211> 277
      <212> PRT
      <213> Homo sapiens


      <400> 1842
 Met Ala Leu Pro Met Gly Cys Leu Trp Glu Trp Ile Glu Ala Leu Gly
   1               5                  10                  15    
 Leu Ala Ile Trp Ser Val Arg Val Gly Ser His Pro Asp Gly Gly Trp
              20                  25                  30        
 Ala Ser Gly Cys Gly Pro Gly Gln Pro Gly Arg Glu Pro Leu Pro Arg
          35                  40                  45            
 Gln Arg Ser Leu Phe Pro Arg Arg Lys Lys Pro Thr Pro Ser Val Gly
      50                  55                  60                
 Gly Glu Cys Ser Gly His Thr Ala Gly Trp Ile Pro Glu Val Gly Thr
  65                  70                  75                  80
 Ser His Cys Ser His Phe Ser Pro Arg Ala Gln Pro Pro Cys Ser Ser
                  85                  90                  95    
 Arg Ser Arg Arg Ser Ala Ala Ala Ile Ser Thr Ile Lys Val Ile Ser
             100                 105                 110        
 Pro Glu Ser Phe Pro Gly Lys Ile Ser Thr Asn Val Ala Leu Pro Trp
         115                 120                 125            
 Phe Ser Ser Ala Ser Gly Pro Leu Leu Ala Thr Pro Ala Pro Cys Phe
     130                 135                 140                
 Leu Pro Ser His Thr Ala Pro Pro Leu Val Ser Asp Pro Pro Pro Asn
 145                 150                 155                 160
 Pro Thr Val Val Ala Pro Arg Val Val Gly Ser Arg Ser Leu Pro Gly
                 165                 170                 175    
 Ala Gly Ser Lys Asp Cys Pro Pro Pro Ser His Ala Leu Pro Ala Ala
             180                 185                 190        
 Ala Ala Gly Glu Ser Gly Asp Ala Gly Pro Gly Ser Gly Ala Ala Glu
         195                 200                 205            
 Val Pro Gly Leu Arg Val Gly Pro Ala Trp Leu His Lys Gly Gly Thr
     210                 215                 220                
 Ala Gln Ser Ala Ala Ser Gly Thr Trp Gly Thr Gly Gly Ala Gly His
 225                 230                 235                 240
 Arg Gly Pro Thr Thr Ala Thr Ala Ala Pro Ala Ala Ala Pro Ala Ala
                 245                 250                 255    
 Thr Ala Ser Ala Met Ala Ala Ala Ala Pro Asp Gly Pro Leu Leu Thr
             260                 265                 270        
 Ser Val Leu Ser Lys
         275        



      <210> 1843
      <211> 166
      <212> PRT
      <213> Homo sapiens


      <400> 1843
 Met Thr Ala Gly Thr Val Val Ile Thr Gly Gly Ile Leu Ala Thr Val
   1               5                  10                  15    
 Ile Leu Leu Cys Ile Ile Ala Val Leu Cys Tyr Cys Arg Leu Gln Tyr
              20                  25                  30        
 Tyr Cys Cys Lys Lys Asp Glu Ser Glu Glu Asp Glu Glu Glu Pro Asp
          35                  40                  45            
 Phe Ala Val His Ser His Leu Pro Pro Leu His Ser Asn Arg Asn Leu
      50                  55                  60                
 Val Leu Thr Asn Gly Pro Ala Leu Tyr Pro Thr Ala Ser Thr Ser Phe
  65                  70                  75                  80
 Ser Gln Lys Ser Pro Gln Ala Arg Ala Leu Cys Arg Ser Cys Ser His
                  85                  90                  95    
 Cys Glu Pro Pro Thr Phe Phe Leu Gln Glu Pro Pro Glu Glu Glu Glu
             100                 105                 110        
 Asp Val Leu Asn Gly Gly Glu Arg Val Leu Tyr Lys Ser Val Ser Gln
         115                 120                 125            
 Glu Asp Val Glu Leu Pro Arg Gly Ala Phe Gly Gly Leu Gln Ala Leu
     130                 135                 140                
 Asn Pro Asn Arg Leu Ser Ala Met Arg Glu Ala Phe Ala Arg Ser Arg
 145                 150                 155                 160
 Ser Ile Ser Thr Asp Val
                 165    



      <210> 1844
      <211> 242
      <212> PRT
      <213> Homo sapiens


      <400> 1844
 Met Leu Leu Ile Thr Ile Leu Gly Tyr Leu Cys Asn Thr Glu Gly Ile
   1               5                  10                  15    
 Ser Leu Thr Leu Arg Lys Asp Val Val Gln Ser Ser Asn Leu Phe Gly
              20                  25                  30        
 Ser Leu Gln Glu Glu Arg Ala Gln Asp Ala Asp Ser Val Trp Gln Gln
          35                  40                  45            
 Gln Gln Ala His Gln Gln His Ser Cys Thr Leu Asp Glu Cys Phe Gln
      50                  55                  60                
 Phe Tyr Thr Lys Glu Glu Gln Leu Ala Gln Asp Asp Ala Trp Lys Cys
  65                  70                  75                  80
 Pro His Cys Gln Val Leu Gln Gln Gly Met Val Lys Leu Ser Leu Trp
                  85                  90                  95    
 Thr Leu Pro Asp Ile Leu Ile Ile His Leu Lys Arg Phe Cys Gln Val
             100                 105                 110        
 Gly Glu Arg Arg Asn Lys Leu Ser Thr Leu Val Lys Phe Pro Leu Ser
         115                 120                 125            
 Gly Leu Asn Met Ala Pro His Val Ala Gln Arg Ser Thr Ser Pro Glu
     130                 135                 140                
 Ala Gly Leu Gly Pro Trp Pro Ser Trp Lys Gln Pro Asp Cys Leu Pro
 145                 150                 155                 160
 Thr Ser Tyr Pro Leu Asp Phe Leu Tyr Asp Leu Tyr Ala Val Cys Asn
                 165                 170                 175    
 His His Gly Asn Leu Gln Gly Gly His Tyr Thr Gly Glu Pro Cys Leu
             180                 185                 190        
 Ala Phe Leu Gln Met Gln Leu Trp Pro Gln Pro Arg Asp Val Pro Gly
         195                 200                 205            
 Met Gly Val Ala Gln Met Leu Ser Ser Leu Gly His Leu Leu Arg Ser
     210                 215                 220                
 Asp Pro Ser Pro Thr Ala His Gln Glu Asp Glu Asp Glu Glu Asn Lys
 225                 230                 235                 240
 Asp Glu
        



      <210> 1845
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 1845
 Met Leu Met Phe Pro Gly Ala Gly Ile Phe Arg Ser Leu Cys Leu Ala
   1               5                  10                  15    
 Val Pro Ile Gln Ser Pro Arg Arg Asn Pro Pro Thr Ala Glu Leu Leu
              20                  25                  30        
 Trp Gly Leu Asp Ala Ile Val Ala Lys Leu Thr Phe His Asp Glu Asn
          35                  40                  45            
 Gly Leu
      50



      <210> 1846
      <211> 422
      <212> PRT
      <213> Homo sapiens


      <400> 1846
 Met Gly Gly Pro Arg Gly Ala Gly Trp Val Ala Ala Gly Leu Leu Leu
   1               5                  10                  15    
 Gly Ala Gly Ala Cys Tyr Cys Ile Tyr Arg Leu Thr Arg Gly Arg Arg
              20                  25                  30        
 Arg Gly Asp Arg Glu Leu Gly Ile Arg Ser Ser Lys Ser Ala Glu Asp
          35                  40                  45            
 Leu Thr Asp Gly Ser Tyr Asp Asp Val Leu Asn Ala Glu Gln Leu Gln
      50                  55                  60                
 Lys Leu Leu Tyr Leu Leu Glu Ser Thr Glu Asp Pro Val Ile Ile Glu
  65                  70                  75                  80
 Arg Ala Leu Ile Thr Leu Gly Asn Asn Ala Ala Phe Ser Val Asn Gln
                  85                  90                  95    
 Ala Ile Ile Arg Glu Leu Gly Gly Ile Pro Ile Val Ala Asn Lys Ile
             100                 105                 110        
 Asn His Ser Asn Gln Ser Ile Lys Asp Lys Ala Leu Asn Ala Leu Asn
         115                 120                 125            
 Asn Leu Ser Val Asn Val Glu Asn Gln Ile Lys Ile Lys Ile Tyr Ile
     130                 135                 140                
 Ser Gln Val Cys Glu Asp Val Phe Ser Gly Pro Leu Asn Ser Ala Val
 145                 150                 155                 160
 Gln Leu Ala Gly Leu Arg Leu Leu Thr Asn Met Thr Val Thr Asn Asp
                 165                 170                 175    
 His Gln His Met Leu His Ser Tyr Ile Thr Asp Leu Phe Gln Val Leu
             180                 185                 190        
 Leu Thr Gly Asn Gly Asn Thr Lys Val Asp Ser Ser Phe Leu Ser Leu
         195                 200                 205            
 Tyr Asp Ser His Val Ala Lys Glu Ile Leu Leu Arg Val Leu Thr Leu
     210                 215                 220                
 Phe Gln His Ile Lys Asn Cys Leu Lys Ile Glu Gly His Leu Ala Val
 225                 230                 235                 240
 Gln Pro Thr Phe Thr Glu Gly Ser Leu Phe Phe Leu Leu His Gly Glu
                 245                 250                 255    
 Glu Cys Ala Gln Lys Ile Arg Ala Leu Val Asp His His Asp Ala Glu
             260                 265                 270        
 Gly Ser Ala Glu Gly Lys Tyr Glu Gly Leu Glu Pro Pro Asn Thr Val
         275                 280                 285            
 Pro Thr Gly Ala Leu Pro Ser Glu Ala Val Arg Arg Gly Pro Pro Ser
     290                 295                 300                
 Ser Arg Pro Lys Asn Ser Arg Ser Thr Asp Ser Leu His Cys Ala Pro
 305                 310                 315                 320
 Ala Lys Ala Thr Asp Pro Gln His His Pro Val Lys Ala Ala Gly Asn
                 325                 330                 335    
 Glu Thr Val Pro Cys Lys Ala Pro Gly Ala Glu Leu Pro Lys Ala Met
             340                 345                 350        
 Gly Gly Ala His Val Leu His Gln Cys Asp Leu Asp Val Cys Asp Leu
         355                 360                 365            
 His Gly Thr Leu Met Gln Arg Val Gly Ser Gln Gly Leu Gly Ser Phe
     370                 375                 380                
 Asn Ala Val Ala Leu Gln Gly Ile Ala Pro Val Ala Met Leu Ser Thr
 385                 390                 395                 400
 Cys Ser Phe Ser Arg Cys Thr Met Gln Ala Val Asn Arg Ser Thr Thr
                 405                 410                 415    
 Leu Ala Ser Arg Gly Ser
             420        



      <210> 1847
      <211> 189
      <212> PRT
      <213> Homo sapiens


      <400> 1847
 Met Gly Phe Val Val Tyr Pro Leu Cys Gln Leu Leu Pro His Ser Thr
   1               5                  10                  15    
 Leu Thr Val Asp Phe Thr Cys Leu Val Thr Tyr Arg Val Ser Gly Glu
              20                  25                  30        
 Ser Arg Ala Pro His Pro Met Ala Glu Leu Phe Leu Val Ile Tyr His
          35                  40                  45            
 Met Glu Glu Lys Leu Glu Thr His Ile Pro Arg Lys Gln Glu Arg Val
      50                  55                  60                
 Glu Glu Lys Gly Pro Cys Ile Cys Lys Ala Leu Ser Pro Asn Ser Val
  65                  70                  75                  80
 Asn Gln Asp Ser Lys Asn Gly Gly Cys Phe His Met Ser Gln Val Gly
                  85                  90                  95    
 Ile Arg Glu Arg Lys Ser Met Lys Met Ile Ser Tyr His Pro Ser Pro
             100                 105                 110        
 His Ser His Pro Lys Arg Ser Ser Met Asp Asp His Val His Tyr His
         115                 120                 125            
 Leu Ser Ile Glu Asp Leu Trp Val Thr Leu Cys Leu Thr Thr Ser Ile
     130                 135                 140                
 Ser Thr Phe Ile His Asp Asp Phe Lys Ile Gln Leu Leu Thr Phe Thr
 145                 150                 155                 160
 Asp Tyr Phe Thr Asn Lys Gln Asn Tyr His Lys Lys Cys Leu Pro Ser
                 165                 170                 175    
 Pro Thr Pro Gln Thr Ile Asn Leu Pro Asn Ser Tyr Asn
             180                 185                



      <210> 1848
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 1848
 Met Ala Leu Pro Leu Ala Ser Trp Val Ala Leu Gly Gln Trp Leu Leu
   1               5                  10                  15    
 Leu Pro Ala Leu Gln Ala Met Ser Val Glu Asn Arg Phe Pro Ala Pro
              20                  25                  30        
 Ile Phe Pro Gln Arg Gln Ala Ala Trp Asn Asp Phe Gly Glu Met Thr
          35                  40                  45            
 Phe Val Gln Leu Cys Arg Ala Cys Arg Ser Ser Ser Ser Ser Pro Thr
      50                  55                  60                
 Ala Ile Val Thr Leu Val Thr Gln Asp Glu Asp Ser Ile Ser Leu Ser
  65                  70                  75                  80
 Pro Asn Asn Lys Asn Tyr Asn Ser Asn Ile Thr Ile Ala Ala Ile Pro
                  85                  90                  95    
 Gln Thr Thr Ser Ser Ile Ser Pro Arg Trp Cys Leu Asp Pro Thr Gln
             100                 105                 110        
 Gly Leu Ala Tyr Arg Cys His Ser Glu Asn Val Cys Arg Met Asn Glu
         115                 120                 125            
 Arg Ser His Phe Ala Ser Gly Glu Asn
     130                 135        



      <210> 1849
      <211> 401
      <212> PRT
      <213> Homo sapiens


      <400> 1849
 Met Gly Leu Phe Gly Phe Trp Arg Lys Tyr Ile Pro His Leu Gly Val
   1               5                  10                  15    
 Leu Leu Trp Pro Ile Tyr Gln Val Asn Arg Lys Ala Ala Gly Phe Glu
              20                  25                  30        
 Trp Cys Pro Glu Gln Glu Thr Ala Leu Gln Gln Val Gln Ala Ala Val
          35                  40                  45            
 Gln Ala Ala Leu Gln Leu Gly Pro Tyr Asp Ser Ala Asp Pro Met Val
      50                  55                  60                
 Leu Glu Val Ser Val Ala Asp Met Asp Ala Val Trp Ser Leu Trp Gln
  65                  70                  75                  80
 Ala Pro Ile Gly Glu Leu Pro Gln Arg Pro Leu Gly Phe Trp Ser Lys
                  85                  90                  95    
 Ala Leu Pro Ser Ser Ala Asp Asn Asp Ser His Phe Glu Gly Gln Leu
             100                 105                 110        
 Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Gln Cys Leu Thr Met Gly
         115                 120                 125            
 Tyr Gln Val Ile Met Gln Pro Lys Leu Pro Ile Met Asn Cys Val Leu
     130                 135                 140                
 Phe Glu Pro Ser Ser His Lys Val Glu Cys Thr Ala Ala Phe His His
 145                 150                 155                 160
 Gln Met Glu Val Val Tyr Met Thr Ser Leu Lys Asp Ser Gly Glu Gly
                 165                 170                 175    
 Lys Ser Ser Gln Trp Ala Glu Leu Arg Ala Val His Leu Val Val His
             180                 185                 190        
 Phe Ala Trp Lys Glu Lys Trp Pro Asp Val Arg Leu Tyr Thr His Thr
         195                 200                 205            
 Trp Val Val Ala Ser Gly Leu Ala Gly Trp Ser Gly Thr Trp Lys Lys
     210                 215                 220                
 His Tyr Trp Lys Ile Gly Asp Lys Glu Ile Trp Gly Arg Gly Lys Gly
 225                 230                 235                 240
 Gln Lys Phe Val Phe Thr Glu Ile Asp Thr Tyr Ser Arg Tyr Gly Phe
                 245                 250                 255    
 Val Tyr Tyr Ala Arg Asn Ala Ser Ala Lys Thr Thr Ile Val Asp Ser
             260                 265                 270        
 Trp Asn Thr Leu Ser Thr Ile Met Val Phe His Pro Ala Phe Ser Leu
         275                 280                 285            
 Thr Lys Ala Leu Thr Leu Trp Leu Gln Lys Cys Gly Ser Arg Ile His
     290                 295                 300                
 Gly Ser Arg Asn Gln Gly Val Glu Leu Glu Val Ala Pro Pro Ile Ile
 305                 310                 315                 320
 Ile Pro Ser Asp Pro Leu Ala Lys Tyr Leu Leu Pro Val Pro Ser Thr
                 325                 330                 335    
 Leu Cys Ser Ala Gly Leu Glu Val Leu Ile Pro Glu Gly Gly Met Leu
             340                 345                 350        
 Pro Pro Gly Asp Thr Thr Met Ile Pro Leu Asn Trp Lys Leu Arg Leu
         355                 360                 365            
 Pro Pro Arg His Phe Gly Leu Ser Leu Pro Leu Ser Gln Gln Ala Lys
     370                 375                 380                
 Lys Gly Val Thr Val Leu Ala Gly Val Ile Asp Pro Asp Tyr Gln Asp
 385                 390                 395                 400
 Glu
    



      <210> 1850
      <211> 223
      <212> PRT
      <213> Homo sapiens


      <400> 1850
 Met Asp Phe Lys Gly Asp Cys Ser Leu Asp Tyr Lys Leu Val Ser Gln
   1               5                  10                  15    
 Leu Trp Leu Ala Val Val Val Val Pro Leu Ala Val Ser Val Ala Cys
              20                  25                  30        
 Leu Asn Ser Asp Cys His Met Ala Thr Ala Leu Pro Leu Gly Pro Gly
          35                  40                  45            
 Ala Ser Gly Leu Leu Thr Gly Thr Val Thr Leu Glu Leu Arg Arg Ala
      50                  55                  60                
 Pro Arg Leu Trp Lys His Ala Gly Leu Leu Val Leu Glu Leu Ser Ala
  65                  70                  75                  80
 Glu Ala Phe Thr Leu Gly Gly Val Leu Val Ser Val His Ala Leu Phe
                  85                  90                  95    
 Leu Leu Ser Gln Arg Lys Pro Gly Cys Cys Arg Ser Gln Ser Leu His
             100                 105                 110        
 Tyr Gln Glu Leu Gln Glu Glu Cys Pro Ser Ser Pro Phe Asp Pro Ser
         115                 120                 125            
 Pro Phe Tyr Cys Ser Gly Asp Tyr Lys Ser Gln Asp Ala Pro Leu Ala
     130                 135                 140                
 Arg Asp Arg Leu Gly Asn Lys Glu Pro Ser Leu Arg Gly Leu Glu Ala
 145                 150                 155                 160
 Ala Thr Thr Asp Met Phe His Gln Ile Leu Val Gly Leu Lys Lys His
                 165                 170                 175    
 Ser Ser Phe Ile Pro Leu Arg Ile Tyr Glu Ile Arg Arg Tyr Trp Ser
             180                 185                 190        
 Ser Ala Lys Phe Asn Val Val Met Lys His Ile Arg Ser Ile Leu Tyr
         195                 200                 205            
 Asn Leu Ala Ser Ser Gln Phe Cys Phe Leu Leu Ser Tyr Ser Ala
     210                 215                 220            



      <210> 1851
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 1851
 Met Thr Met Ser Gln Cys Phe Lys Ala Ile Leu Ile Leu Thr Ala Gln
   1               5                  10                  15    
 Leu Leu Val Ile Ile Ser Trp Met Arg Asp Lys Glu Glu Leu Ser Asn
              20                  25                  30        
 Phe His Gln Ser Ile Ser Arg His Gln Glu Asn Val Pro Cys Glu His
          35                  40                  45            
 Ile Pro Leu Glu Pro Thr Gly Ser Gly Asp Arg Arg Asp Ile Ser Gln
      50                  55                  60                
 Leu Gln Glu Ala Lys Gly Ile Lys Trp Asn Asn Val Ala Leu Leu Trp
  65                  70                  75                  80
 Lys Ile Gly Leu Cys Ser Leu Asn Leu Pro Gly Ser Trp Pro Cys Val
                  85                  90                  95    
 Thr Val Leu Glu Ser Gly Leu Gln Gly Ile Ser Thr Phe Gly Glu Glu
             100                 105                 110        
 Thr Glu Ala Gln Asp Thr His Asn Leu Ser Ser Gln Arg Val Cys Met
         115                 120                 125            
 Leu Cys Ala Glu Cys Tyr Ala Ala Asn Glu Val Leu Arg Asp Val Phe
     130                 135                 140                
 Arg Thr Leu Glu Arg Tyr Ile Phe Ala Leu Met Ala Ser Leu His Leu
 145                 150                 155                 160
 Phe Pro Leu Gly Gln Lys Pro Ser Glu Gly Arg Phe
                 165                 170        



      <210> 1852
      <211> 234
      <212> PRT
      <213> Homo sapiens


      <400> 1852
 Met Gly Ile Phe Met Val Val Gly Lys Leu Leu Val Pro Arg Thr Arg
   1               5                  10                  15    
 Ala Ser Gly Ala Ser Arg Tyr Asn Ser Gln Ile Trp Trp Pro Leu Lys
              20                  25                  30        
 Gln Leu Lys Ser Ala Asp Thr Phe Pro Phe Phe Pro Ser Leu Leu His
          35                  40                  45            
 Glu Leu Ala Arg Ser Arg Trp Arg Ile His His Thr Tyr Cys Glu Ala
      50                  55                  60                
 Ser Lys Cys Leu Glu Ser Asn Lys Leu Asp Leu Ile Tyr Leu Leu Val
  65                  70                  75                  80
 Asp Pro Glu Cys Ile Ala Arg Ile Leu Tyr Cys Leu Arg Val Asp Met
                  85                  90                  95    
 Leu Asn Val Ala Cys Gln Ile Ser Gly Ala Glu Lys Ala Cys Ala Gln
             100                 105                 110        
 Tyr Val Val Met Val Glu Ser Gly Gly Val Gly Trp Lys Trp Leu Gly
         115                 120                 125            
 Asn Arg Gln Ser Phe Tyr Leu Ser Glu Leu Thr Gln Leu Val Ile Gly
     130                 135                 140                
 Lys Ala Lys Thr Gly Leu Asp Ser Leu Ser Thr Glu Lys Gly Arg Lys
 145                 150                 155                 160
 Leu Leu Thr Ile Glu Gly Ser Val Val Arg Gly Glu Val Gln Arg Ser
                 165                 170                 175    
 Val Leu Arg Lys Glu Lys Leu Thr Glu Arg Ile Leu Glu Ala Leu Ala
             180                 185                 190        
 Phe Leu Leu Leu Gln His Leu Leu Arg Ser Tyr Val Val Val Thr Trp
         195                 200                 205            
 Ala Thr Ala Ser Ser Arg Leu Met Phe Arg Ala Leu Leu Gln Thr Ala
     210                 215                 220                
 Ala Ala Arg Gly Ser Thr Ala Gln Leu Thr
 225                 230                



      <210> 1853
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 1853
 Met Pro Gly Leu Thr Cys Ala Pro Val Asp Gly Ala Val Leu Val Arg
   1               5                  10                  15    
 Val Phe Leu Gly Leu Leu Val Gln His Arg Leu Val Leu Asp Phe Glu
              20                  25                  30        
 Asn Asp Phe Arg Val Leu Val Pro Thr Val Cys Lys Val Pro Thr Val
          35                  40                  45            
 Cys Arg Val Pro Thr Val Cys Lys Val Pro Ser Val Cys Lys Gly Ala
      50                  55                  60                
 Cys Asp Lys Val Ile Pro Ala Ser Val Gly Val Glu Asp Asp Ser Asp
  65                  70                  75                  80
 Val His Glu Arg Cys Asp Val Ala Ser Gly Val Ala Ser Tyr Ala Pro
                  85                  90                  95    
 Arg Thr Thr Asp Leu Leu Val Tyr Leu Thr Pro Ser Glu Thr Ala Glu
             100                 105                 110        
 Phe Ala Gln Pro Val Val Arg Asn Gly
         115                 120    



      <210> 1854
      <211> 160
      <212> PRT
      <213> Homo sapiens


      <400> 1854
 Met Ala Arg Leu Gly Ala Val Arg Ser His Tyr Cys Ala Leu Leu Leu
   1               5                  10                  15    
 Ala Ala Ala Leu Ala Val Cys Ala Phe Tyr Tyr Leu Gly Ser Gly Arg
              20                  25                  30        
 Glu Thr Phe Ser Ser Ala Thr Lys Arg Leu Lys Glu Ala Arg Ala Gly
          35                  40                  45            
 Ala Pro Ala Ala Pro Ser Pro Pro Ala Leu Glu Leu Ala Arg Gly Ser
      50                  55                  60                
 Val Ala Pro Ala Pro Gly Ala Lys Ala Lys Ser Leu Glu Gly Gly Gly
  65                  70                  75                  80
 Ala Gly Pro Val Asp Tyr His Leu Leu Met Met Phe Thr Lys Ala Glu
                  85                  90                  95    
 His Asn Ala Ala Leu Gln Ala Lys Ala Arg Val Ala Leu Arg Ser Leu
             100                 105                 110        
 Leu Arg Leu Ala Lys Phe Glu Ala His Glu Val Leu Asn Leu His Phe
         115                 120                 125            
 Val Ser Glu Glu Ala Ser Arg Glu Val Ala Lys Gly Leu Leu Arg Glu
     130                 135                 140                
 Leu Leu Pro Pro Ala Ala Gly Phe Lys Cys Lys Leu Pro Leu Gln Arg
 145                 150                 155                 160





      <210> 1855
      <211> 328
      <212> PRT
      <213> Homo sapiens


      <400> 1855
 Met Ala Ala Leu Leu Leu Leu Asp Leu Gln Gly Leu Ser Ala Ala Leu
   1               5                  10                  15    
 Arg Ser Gly Pro Gly Tyr Ser Pro His Pro His Asn Phe Leu Arg Ser
              20                  25                  30        
 Asp Ser Met Leu Arg Ser Val Ala Trp Trp Leu Ser Ser Pro Arg Ala
          35                  40                  45            
 Gln Cys Lys Pro Ala Glu Asp Ala Ser Ser Ser Phe Trp Gly Arg Asn
      50                  55                  60                
 Arg Gln Thr Ser Gly Pro Gly Leu Gly Ser Gln Trp His Pro Arg Ile
  65                  70                  75                  80
 Thr Pro Cys Ser Leu Ala Leu Ser Leu Asn Cys Val Leu Glu Ala Ser
                  85                  90                  95    
 Ser Gly Pro Val Lys Ser Val Pro Lys Asp Ala Cys Leu Cys Thr Arg
             100                 105                 110        
 Pro Val Gly Leu His Leu Ser Phe Gly Asp Gln Pro Ala Ile Pro Ala
         115                 120                 125            
 Gly Ser Gly Gly Val Glu Met Gly Lys Asp Ser Leu Glu Lys Lys Glu
     130                 135                 140                
 Arg Lys Gly Leu Leu Cys Cys Phe Leu Thr Ala Gly Gln Ser Leu Ala
 145                 150                 155                 160
 Trp Arg Lys Leu Lys Pro Phe Arg Glu Ala Gly Pro Ser Ser Gly Gln
                 165                 170                 175    
 Arg Leu Gly Arg Gln Val Glu Val Val Ser Val Phe Leu Glu Ala Arg
             180                 185                 190        
 Leu Met Val Gln Tyr Met Ala Gly Ile Gln Gln Val Leu Asp Lys Trp
         195                 200                 205            
 Trp Val Asn Arg Thr Asp Ala Lys Leu Lys Asp Ser Arg Gly Gly Val
     210                 215                 220                
 Glu Gly Met Thr Ile Arg Gly Gly Phe Glu Glu Glu Asp Tyr Leu Thr
 225                 230                 235                 240
 Trp Ala Leu Lys Asn Ala Glu Glu Phe Ser Pro Pro Arg Ala Glu Leu
                 245                 250                 255    
 Ser Tyr Pro Asp Arg Ser Ala Ser Gln Gly Ser Val Tyr Ser Arg His
             260                 265                 270        
 Thr Ser Gly Pro Ala Met Ala Ile Arg Asp Ser Phe Pro Leu Cys Pro
         275                 280                 285            
 Pro Pro Ala Glu Ala Phe Asn Thr Ser Gly Gly Arg Ala Ala Thr Val
     290                 295                 300                
 Lys Ser Ser Gly Glu Ser Lys Lys Asp Pro Gly Thr Val Ala Cys Arg
 305                 310                 315                 320
 Gly Pro Glu Ser Phe Ser Met Pro
                 325            



      <210> 1856
      <211> 129
      <212> PRT
      <213> Homo sapiens


      <400> 1856
 Met Glu Ser Cys Phe Leu Leu Trp Leu Ala Gln Met Leu Val Glu Ser
   1               5                  10                  15    
 Ser His Ala Ala Arg Met His Ser Ser Phe Gln Arg Gln His Arg Arg
              20                  25                  30        
 Arg Met Arg Val Arg Leu Tyr Arg Glu Ser Ala Gln Val Met Gln His
          35                  40                  45            
 Trp Leu Arg Val Pro Thr Ala Ala Lys Gln Leu His Gln Asp Ala Gly
      50                  55                  60                
 Ala Thr Gly Ser His Gln Arg Ser Thr Met Ala Leu Pro Ser Thr Ala
  65                  70                  75                  80
 Ala Thr Lys Ala Leu Leu Glu Leu Thr Leu Leu Leu Ala Ala Asp Val
                  85                  90                  95    
 Ala Ser Asn Pro Ser Pro Gln Gln Gln Ser Thr Ser Thr Ala Tyr Ile
             100                 105                 110        
 Pro Pro Ser Val Glu Leu Arg Met Glu Ala Ile Phe Arg Glu Ala Val
         115                 120                 125            
 His
    



      <210> 1857
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1857
 Met Gly Glu Asn Leu Leu Arg Leu Leu Leu Ala Lys Ile Thr Leu Leu
   1               5                  10                  15    
 Asp Arg Leu Gln Gly Glu Gln Gly Arg Arg Met Asn Arg Glu Asn Lys
              20                  25                  30        
 Ser Glu Ala Phe Ser Leu Pro Ser Thr Gln Arg Asp Ile Pro His Tyr
          35                  40                  45            
 Gln Gly Ala Glu Glu Ala Val Ser Ile Glu His Leu Ser Arg Gln Asp
      50                  55                  60                
 Leu Lys Val Lys Gly Lys Glu Arg Gly Gly Gly Gly Gly Gly Lys Lys
  65                  70                  75                  80
 Arg Arg Arg Lys Arg Arg Arg Arg Trp Lys Glu Arg Lys Lys Arg Lys
                  85                  90                  95    
 Glu Lys Arg Lys Lys Glu Glu Glu Glu Glu Glu Glu Glu Glu Pro Asp
             100                 105                 110        
 Gly Glu Lys Glu Gln Glu Met Ala Ala Ser Cys His Leu Ser Cys Pro
         115                 120                 125            
 Glu Gly
     130



      <210> 1858
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 1858
 Met Gln Ala Gly Gln Pro Trp Leu Val His Leu Pro Leu Leu Pro Ala
   1               5                  10                  15    
 Ala Ser Ile Trp Gln Thr Phe Phe Ser Trp Gly Ala Asp Ser His Gly
              20                  25                  30        
 Gly Trp Gly Ala Gly Leu Ser Arg Ala Gly Ser Arg Lys Thr Ala Gln
          35                  40                  45            
 Lys Ala Gly Ser Asp Ser Gly Gly Trp Val Gln Leu His Cys Pro Gly
      50                  55                  60                
 Val Glu Val Gly Asp Trp Thr
  65                  70    



      <210> 1859
      <211> 248
      <212> PRT
      <213> Homo sapiens


      <400> 1859
 Met Gln Pro Val Ser Ile Leu Ala Leu Cys Ser His Tyr Cys Phe Leu
   1               5                  10                  15    
 Phe Lys Leu Arg Ile Met Ala Lys Ile Glu Leu Ser Ser Leu Lys Lys
              20                  25                  30        
 Lys Phe Lys Glu Ala Pro His Pro Thr Glu Ser His Phe Tyr Cys Ser
          35                  40                  45            
 Ile Lys Ser Pro His Ser Pro Ser Phe Lys Ala Met Gly Pro Asp Phe
      50                  55                  60                
 Phe Leu Asp Ala Gly Gln Glu Pro Gly Lys Phe Ser Leu Ala Val Asp
  65                  70                  75                  80
 Ser Asn Ala Glu Glu Val Ser Glu Gly Ser Leu Leu Ser Leu Val Thr
                  85                  90                  95    
 Val Gly Glu Pro Trp Asp Val Ser Leu Glu Glu Ser Ser Phe Phe Asn
             100                 105                 110        
 Phe Ser Asp Thr Glu Leu Pro Glu Gly Phe Val Gly Val Cys Pro Val
         115                 120                 125            
 Asp Phe Ser Lys Val Val Thr Phe Leu Leu Thr Val Ala Ala Gly Ala
     130                 135                 140                
 Thr Lys Arg Pro Ala Arg Val Cys Thr Arg Thr Tyr Thr His Ser His
 145                 150                 155                 160
 Thr Asn Thr Lys Leu Glu Gly Ile Tyr Phe Met Tyr Ile Ile Arg Asp
                 165                 170                 175    
 Leu Leu Lys Asp Val His His Ser Ile Ile Tyr Gly Asn Gly Glu Leu
             180                 185                 190        
 Glu Gly Leu Leu Thr Asp Leu Ser Thr Tyr Pro Asn Ser His Pro Pro
         195                 200                 205            
 Arg Val Gln Glu Pro Lys Ala Asn Asp Ala Lys Val Ser Thr Ala Lys
     210                 215                 220                
 Gly Lys Val Gly Gln Val Ser Leu Arg Ser His Leu Glu Gln Thr Glu
 225                 230                 235                 240
 Pro His Thr Cys Pro Pro Leu Lys
                 245            



      <210> 1860
      <211> 211
      <212> PRT
      <213> Homo sapiens


      <400> 1860
 Met Leu Gly Lys Leu Ile Val Tyr Leu Tyr Leu Thr Phe Ser Ser Ala
   1               5                  10                  15    
 Glu Thr Met Asn Gln Gly Lys Leu Phe His Ala Cys Gly Ala Gly Gln
              20                  25                  30        
 Ile Glu Trp Lys Gly Ile Val Asn Ile Glu Ile Leu Phe Ser Tyr His
          35                  40                  45            
 Leu Leu Arg Val Phe Ser Leu Leu Tyr Gly His Gly Asn Cys Leu Ile
      50                  55                  60                
 Leu Ile Phe Glu Leu Trp Asp Ser Ala Ala Glu Lys Leu Gly Pro Lys
  65                  70                  75                  80
 Thr Asn Gln Pro Lys Glu His Leu Thr Asn Phe Lys Ser Glu Glu Gly
                  85                  90                  95    
 Gln Val Pro Gln Pro Arg Ile Ser Val Pro Gln Ser Leu Ile Ser Val
             100                 105                 110        
 Pro Gln Pro Leu Ile Ser Leu His Pro Asn Pro Leu Phe Pro Cys Pro
         115                 120                 125            
 Glu Pro Leu Phe Leu Cys Pro Asp Pro Leu Phe Pro Cys Thr Tyr Pro
     130                 135                 140                
 Leu Phe Pro Cys Pro Asn Pro Leu Ser Leu Cys Pro Ile Pro Tyr Phe
 145                 150                 155                 160
 Cys Ala Pro Thr Ser Tyr Leu Cys Ala Pro Thr Pro Phe Pro Thr Phe
                 165                 170                 175    
 Leu Glu Gly Ala Cys Tyr Met Cys Gln Lys Ser Gly His Trp Ala Lys
             180                 185                 190        
 Glu Cys Pro Gln Arg Arg Ile Pro Pro Lys Pro Arg Pro Ile Tyr Val
         195                 200                 205            
 Gly Pro His
     210    



      <210> 1861
      <211> 217
      <212> PRT
      <213> Homo sapiens


      <400> 1861
 Met Leu Gln Pro Phe Tyr Ser His Leu Leu Gln Leu Val Ser Arg Gly
   1               5                  10                  15    
 Val Arg Ala Leu Phe Ala Pro Thr Val Gln Gln Ile Pro Gly Ser Cys
              20                  25                  30        
 Pro Met Thr Lys Arg Asn Glu Val Thr Asp Thr Gly Glu Arg His Ile
          35                  40                  45            
 Met Leu Thr Val Arg Ser Asp Ser Leu Ile Thr Ala Gly Asn Lys Asn
      50                  55                  60                
 Gly Lys Asn Arg Gln Ala Phe Arg Gly Ser Val Asp Val Gly Ala Pro
  65                  70                  75                  80
 Lys Pro Ile Ala Ile Glu Pro Cys Ala Gly Asn Arg Ala Ala Val Leu
                  85                  90                  95    
 Thr Val Phe Leu Cys Leu Pro Arg Gly Ser Ser Gly Ala Pro Pro Pro
             100                 105                 110        
 Gly Gln Ser Gly Ile Pro Pro Gly Leu Ile Leu Ser Gln Leu Leu Leu
         115                 120                 125            
 Pro Leu His Ser Leu Arg Glu Asn Phe Ser Ala Ala Asn Cys Arg Ser
     130                 135                 140                
 Cys Gly Ser Ser Ala Asn Thr Ser His Leu Leu Ser Ser Ser Ile Ser
 145                 150                 155                 160
 Thr Trp Ile Ser Ser Arg Ser Glu Lys His Arg Ala Arg Lys Gly Thr
                 165                 170                 175    
 Glu Met Thr Tyr Gly Ser Ser Asn Cys Met Gln Pro Gln Leu Val Thr
             180                 185                 190        
 Leu Ser Arg Ile Ile Leu Asp Arg Gln Thr Val Ser Lys Asp Ile Pro
         195                 200                 205            
 Lys Ser His Ala Asp Asn Phe Arg Asp
     210                 215        



      <210> 1862
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1862
 Met Pro Arg Arg Val Leu Leu Pro Ile Leu Pro Gly Leu Ser Arg Ala
   1               5                  10                  15    
 Gly Gly Thr Thr Arg Gly Arg Gly Leu Pro Gly Arg Ser Gly Leu Gln
              20                  25                  30        
 Gly Ala Ala Val Pro Pro Pro Ala Gly Ile Leu Gln Tyr Lys Lys Arg
          35                  40                  45            
 Phe Ser Glu Leu Glu Gln Leu Leu Glu Arg Ser Gly Glu Leu Glu Gln
      50                  55                  60                
 Gln Gln Leu Arg Asp Ala Glu His Ser Gln Asp Leu Glu Ile Ala Leu
  65                  70                  75                  80
 Ile Trp Leu Glu Glu Glu Gln Gln Gly Gly Pro Gly Leu Ala Ala Trp
                  85                  90                  95    
 Pro Pro Gly Arg Ala Pro Thr Asp Pro Leu Cys Pro Ile Gln Glu Cys
             100                 105                 110        
 Gln Pro Gly Pro Gly Glu Cys His Ala Leu Arg Thr Ala Gly Leu Gly
         115                 120                 125            
 Arg Phe Gly Gln Pro Gly Ser Glu
     130                 135    



      <210> 1863
      <211> 420
      <212> PRT
      <213> Homo sapiens


      <400> 1863
 Met Pro Asn Ser Leu Ser Cys Ala Leu Ala Gly Val Leu Leu Leu Pro
   1               5                  10                  15    
 Pro Leu Leu Ala Ala Leu Pro Ala Arg Ile Ile Asn Gln Trp Lys Val
              20                  25                  30        
 Ile Glu Ala Met Asp Gln Gln Asn Gly Tyr Arg Gly Lys Thr Ala Val
          35                  40                  45            
 Ala Ala Ala Val Val Leu Gly Ser Asp Ser Glu Val Gln Ala Lys Val
      50                  55                  60                
 Val Ser Asp Gly Asn Glu Glu Leu Leu Gly Asn Trp Ser Lys Gly His
  65                  70                  75                  80
 Tyr Cys Tyr Ala Leu Ala Lys Arg Leu Ser Ala Phe Cys Pro Cys Pro
                  85                  90                  95    
 Arg Asp Leu Trp Asn Ser Glu Cys Glu Arg Asp Asp Val Lys Leu Glu
             100                 105                 110        
 Pro Met Phe Lys Arg Glu Gly Glu His Lys Ser Leu Glu Asn Leu Gln
         115                 120                 125            
 Pro Asp Asp Ala Ile Glu Lys Glu Asn Pro Phe Ser Gly Glu Thr Phe
     130                 135                 140                
 Lys Leu Pro Ala Glu Ile Cys Ile Ser Asn Lys Glu Gln Asn Val Asn
 145                 150                 155                 160
 Cys Gln Asp His Gly Glu Asn Val Pro Arg Ala Cys Gln Arg Ser Trp
                 165                 170                 175    
 Trp Gln Pro Leu Pro Ser Glu Ala Trp Arg Pro Arg Arg Lys Ile Trp
             180                 185                 190        
 Phe His Gly Ser Ala Arg His Tyr Val Gln Pro Trp Asp Leu Val Pro
         195                 200                 205            
 Cys Ile Ser Ala Met Ala Lys Arg Asp Gln Gly Leu Glu Pro Ser Trp
     210                 215                 220                
 Arg Thr Ser Ala Arg Ala Met Gln Lys Gly Asn Val Gly Ser Glu Pro
 225                 230                 235                 240
 Pro His Arg Val Pro Thr Gly Ala Leu Pro Ser Gly Ala Val Arg Arg
                 245                 250                 255    
 Gly Pro Pro Ser Ser Arg Pro Gln Asn Gly Ser Ser Thr Asp Ser Leu
             260                 265                 270        
 His Cys Val Pro Arg Lys Ala Glu Asp Ile Gln Cys Lys Pro Met Lys
         275                 280                 285            
 Ala Glu Arg Gly Thr Val Pro Cys Glu Ala Thr Gly Val Ala Ala Gln
     290                 295                 300                
 Gly Tyr Gly Ser Pro Pro Leu Ala Ser Val Cys Leu Arg Ser Leu Asn
 305                 310                 315                 320
 Gly Ala Ala Gly Ser His Tyr Gln Tyr Gln Ile Gly Gln Ala Met Phe
                 325                 330                 335    
 Ser Leu Cys Met Val Glu Ser Gly Ala Asp Glu Val Asn Leu His Gly
             340                 345                 350        
 Val Thr Ser Leu Gly Leu Lys Gln Ala Leu Glu Phe Ala Tyr Thr Gly
         355                 360                 365            
 Gln Leu Ala Val Pro Thr Trp Gln Val Lys Gly Pro Glu Ala Pro Pro
     370                 375                 380                
 Leu Cys Leu Ala Leu Trp Arg Val His Ser Glu Ile His Ile Leu Arg
 385                 390                 395                 400
 Lys Asn Ile Ala Ser Leu Pro Tyr Leu Leu Gly Leu Tyr Ser Lys Thr
                 405                 410                 415    
 Pro Val Asp Ala
             420



      <210> 1864
      <211> 486
      <212> PRT
      <213> Homo sapiens


      <400> 1864
 Met Ala Phe Gly Val Arg Cys Thr Trp Val Gln Ile Val Val Leu Leu
   1               5                  10                  15    
 Leu Ile Ser Ser Gly Thr Leu Asp Asp Tyr Phe Pro Tyr Ala Ala Pro
              20                  25                  30        
 Pro Pro Gln Glu Pro Val Lys Thr Leu Arg Ser Leu Val Asn Ile Arg
          35                  40                  45            
 Lys Asp Thr Leu Arg Leu Val Lys Cys Ala Glu Glu Val Lys Ser Pro
      50                  55                  60                
 Gly Glu Glu Ala Ser Lys Ala Lys Val His Tyr Asn Val Glu Phe Thr
  65                  70                  75                  80
 Phe Asp Thr Asp Ala Arg Val Ala Ile Thr Ile Tyr Tyr Gln Ala Thr
                  85                  90                  95    
 Glu Glu Phe Gln Asn Gly Ile Ala Ser Tyr Ile Pro Lys Asp Asn Ser
             100                 105                 110        
 Leu Gln Ser Glu Thr Val Gln Tyr Lys Arg Gly Val Cys Gln Gln Phe
         115                 120                 125            
 Cys Leu Pro Ser His Thr Val Asp Pro Ser Glu Trp Ala Glu Glu Glu
     130                 135                 140                
 Leu Gly Phe Asp Leu Asp Arg Glu Val Tyr Pro Leu Val Val His Ala
 145                 150                 155                 160
 Val Val Asp Glu Gly Asp Glu Tyr Phe Gly His Cys His Val Leu Leu
                 165                 170                 175    
 Gly Thr Phe Glu Lys Val Asp Gly Val Ser Tyr Leu Leu Gln Glu Ile
             180                 185                 190        
 Tyr Gly Ile Glu Asn Lys Tyr Asn Thr Gln Asp Ser Lys Val Ala Glu
         195                 200                 205            
 Asp Glu Val Ser Asp Asn Ser Ala Glu Cys Val Val Cys Leu Ser Asp
     210                 215                 220                
 Val Arg Asp Thr Leu Ile Leu Pro Cys Arg His Leu Cys Leu Cys Asn
 225                 230                 235                 240
 Thr Cys Ala Asp Thr Leu Arg Tyr Gln Ala Asn Asn Cys Pro Ile Cys
                 245                 250                 255    
 Arg Leu Arg Lys Pro Gln Ser Gly Arg Gly Thr Ala Phe Arg Ala Leu
             260                 265                 270        
 Leu Gln Ile Arg Ala Met Arg Lys Lys Leu Gly Pro Leu Ser Pro Thr
         275                 280                 285            
 Ser Phe Asn Pro Ile Ile Ser Ser Gln Thr Ser Asp Ser Glu Glu His
     290                 295                 300                
 Pro Ser Ser Glu Asn Ile Pro Pro Gly Tyr Glu Val Val Ser Leu Leu
 305                 310                 315                 320
 Glu Ala Leu Asn Gly Pro Leu Thr Pro Ser Pro Ala Val Pro Pro Leu
                 325                 330                 335    
 His Val Leu Gly Asp Gly His Leu Ser Gly Met Leu Pro Ser Tyr Gly
             340                 345                 350        
 Ser Asp Gly His Leu Pro Pro Val Arg Thr Ile Ser Pro Leu Asp Arg
         355                 360                 365            
 Leu Ser Asp Ser Ser Ser Gln Gly Leu Lys Leu Lys Lys Ser Leu Ser
     370                 375                 380                
 Lys Ser Thr Ser Gln Asn Ser Ser Val Leu His Glu Glu Glu Asp Glu
 385                 390                 395                 400
 His Ser Cys Ser Glu Ser Glu Thr Gln Leu Ser Gln Arg Pro Ser Val
                 405                 410                 415    
 Gln His Leu Gly Glu Ile Ser Thr Asp Thr Val Ser Ser Met Ser Gly
             420                 425                 430        
 Ser Tyr Ile Ala Pro Gly Thr Glu Glu Glu Gly Glu Ala Leu Ser Ser
         435                 440                 445            
 Pro Gln Pro Ala Ser Arg Ala Pro Ser Glu Glu Gly Glu Gly His Leu
     450                 455                 460                
 Gln Ser Thr Arg Met Pro Gly Leu Asp Thr Asp Ala Pro Ala Asp Val
 465                 470                 475                 480
 Ile Leu Leu Leu Leu Leu
                 485    



      <210> 1865
      <211> 321
      <212> PRT
      <213> Homo sapiens


      <400> 1865
 Met Glu Trp Glu Leu Asn Leu Leu Leu Tyr Leu Ala Leu Phe Phe Phe
   1               5                  10                  15    
 Leu Leu Phe Leu Leu Phe Leu Leu Leu Phe Val Val Ile Lys Gln Leu
              20                  25                  30        
 Lys Asn Ser Val Ala Asn Thr Ala Gly Ala Leu Gln Pro Gly Arg Ser
          35                  40                  45            
 Arg Cys Thr Ala Ser Leu Gly Ala Ser Pro Glu Ser Lys Arg Cys Asp
      50                  55                  60                
 Pro Ser Ala Gly Thr Gly Gly Arg Ala Pro Glu Leu Arg Gly Ala Gly
  65                  70                  75                  80
 Leu Gly Leu Arg Leu Asp Ser Pro Ser Ser Arg Pro Pro Ser Phe Gln
                  85                  90                  95    
 Val Arg Gly Ser Ala Ala Leu Thr Gly Pro Phe Arg Arg Glu Ala Gln
             100                 105                 110        
 Gly Pro Ala Ser Pro Leu Leu Trp Glu Ala Arg Gly Ser Gln Arg Val
         115                 120                 125            
 Arg Val Pro Gly Thr Pro Pro Thr Thr Val Ser Ala Cys Gly Leu Pro
     130                 135                 140                
 Cys Arg Val Gly Phe Glu Ser Gly Thr Ala Asp Gly Glu Arg Tyr Ser
 145                 150                 155                 160
 Glu Ser His Leu Glu Asp Ala Leu Gly Leu Ala Ala Glu Leu Leu Pro
                 165                 170                 175    
 Leu Thr Gly Ala Gln Gly Thr Thr Ala Ala Met Thr Val Trp Ala Cys
             180                 185                 190        
 Lys Lys Lys Ala Gly Thr Thr Gly Asp Gly Ser Phe Leu Gln Met Val
         195                 200                 205            
 Phe Lys Met Ala Ser Asp Leu Ile Arg Thr Ile Leu Ala Val Ala Leu
     210                 215                 220                
 Ile Ser Lys Leu Val Pro Arg Trp Ser Pro Gln His Pro Thr Arg Arg
 225                 230                 235                 240
 Arg Arg Lys Pro Thr Glu Lys Thr Gly His Ala Ser Ser Asn Pro Leu
                 245                 250                 255    
 Pro Phe Lys Glu Leu Pro Gln Gln Pro Asn Asn Phe Cys Leu His Leu
             260                 265                 270        
 Ile Gly Gln Asn Cys Val Ile Gly Tyr Cys Tyr Leu Gln Asp Cys Leu
         275                 280                 285            
 Arg Asn Val Val Phe Val Ala Gly Tyr Ile Thr Ala Phe Asp Lys Asn
     290                 295                 300                
 Pro Val Ser Leu Asp Glu Glu Glu Asp Asp Gly Gly Ser Trp Glu Asp
 305                 310                 315                 320
 Asn
    



      <210> 1866
      <211> 89
      <212> PRT
      <213> Homo sapiens


      <400> 1866
 Met Ser Leu Lys Gly Gln Gly Gly Gln Ser Pro Ile Val Leu Ile Leu
   1               5                  10                  15    
 Asn Arg Lys Ser Val Ala Phe Ser Met Leu Trp Leu Leu Ser Met Ser
              20                  25                  30        
 Ala Gln Pro Gly Pro Leu Pro Gln Ser Asn Thr Pro Val Ala Ile Ala
          35                  40                  45            
 Pro Gly Leu Pro Val Cys His Gly Glu Ser Thr Ser Ser Ser Gly Ile
      50                  55                  60                
 Ala Arg Tyr Ser Cys Tyr Met Lys Asn Ser Asp Ile Thr Glu Gly Ala
  65                  70                  75                  80
 Val Ala Arg Lys Gln Ser Ser Gly Leu
                  85                



      <210> 1867
      <211> 64
      <212> PRT
      <213> Homo sapiens


      <400> 1867
 Met Val Leu Val Leu His His Ile Leu Ile Ala Val Val Gln Phe Leu
   1               5                  10                  15    
 Arg Arg Gly Gln Gln Val Phe Leu Lys Pro Asp Glu Pro Pro Pro Pro
              20                  25                  30        
 Pro Gln Pro Cys Ala Asp Ser Leu Gln Gly Gly Asp Pro Ser Ser Ser
          35                  40                  45            
 Ser Glu Phe Tyr Ser Cys Ala Gly Thr Ala Ala Gln Thr Lys Ser Pro
      50                  55                  60                





      <210> 1868
      <211> 246
      <212> PRT
      <213> Homo sapiens


      <400> 1868
 Met Trp Arg Leu Val Pro Pro Lys Leu Gly Arg Leu Ser Arg Ser Leu
   1               5                  10                  15    
 Lys Leu Ala Ala Leu Gly Ser Leu Leu Val Leu Met Val Leu His Ser
              20                  25                  30        
 Pro Ser Leu Leu Ala Ser Trp Gln Arg Asn Glu Leu Thr Asp Arg Arg
          35                  40                  45            
 Phe Leu Gln Leu Asn Lys Cys Pro Ala Cys Phe Gly Thr Ser Trp Cys
      50                  55                  60                
 Arg Arg Phe Leu Asn Gly Gln Val Val Phe Glu Ala Trp Gly Arg Leu
  65                  70                  75                  80
 Arg Leu Leu Asp Phe Leu Asn Val Lys Asn Val Tyr Phe Ala Gln Tyr
                  85                  90                  95    
 Gly Glu Pro Arg Glu Gly Gly Arg Arg Arg Val Val Leu Lys Arg Leu
             100                 105                 110        
 Gly Ser Gln Arg Glu Leu Ala Gln Leu Asp Gln Ser Ile Cys Lys Arg
         115                 120                 125            
 Ala Thr Gly Arg Pro Arg Cys Asp Leu Leu Gln Ala Met Pro Arg Thr
     130                 135                 140                
 Glu Phe Ala Arg Leu Asn Gly Asp Val Arg Leu Leu Thr Pro Glu Ala
 145                 150                 155                 160
 Val Glu Gly Trp Ser Asp Leu Val His Cys Pro Ser Gln Arg Leu Leu
                 165                 170                 175    
 Asp Arg Leu Val Arg Arg Tyr Ala Glu Thr Lys Asp Ser Gly Ser Phe
             180                 185                 190        
 Leu Leu Arg Asn Leu Lys Asp Ser Glu Arg Met Gln Leu Leu Leu Thr
         195                 200                 205            
 Leu Ala Phe Asn Pro Glu Pro Leu Val Leu Gln Ser Phe Gly His Leu
     210                 215                 220                
 Ile Arg Gly Gln Val Gly Glu Asp Glu Val Gly Glu Arg Asp Ser Gly
 225                 230                 235                 240
 Arg Gly Gly Phe Asn Leu
                 245    



      <210> 1869
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 1869
 Met Trp Asn Phe Ile Leu Ser Ala Leu Asn Leu Gly Val Trp Leu Pro
   1               5                  10                  15    
 Val Gln Lys Pro Asn Asn Glu Ile Gly Phe Leu Arg Gln Ser Arg Gln
              20                  25                  30        
 Asp Cys Ala Val Gly Lys Gly Thr Asp Ala Gly Pro Gly Arg Gly Val
          35                  40                  45            
 Val Ile
      50



      <210> 1870
      <211> 389
      <212> PRT
      <213> Homo sapiens


      <400> 1870
 Met Leu Ser Leu Ala Ala Lys Leu Val Ala Phe Phe Trp Arg Thr Ala
   1               5                  10                  15    
 Asp Thr Pro Arg Glu Glu Ala Gly Gln Leu Glu Pro Glu Leu Ala Glu
              20                  25                  30        
 Gly Asp Thr Lys Leu Lys Thr Val Arg Gly Val Val Thr Arg Tyr Cys
          35                  40                  45            
 Ser Asp Tyr Gly Met Ile Asp Asp Met Ile Tyr Phe Ser Ser Asp Ala
      50                  55                  60                
 Val Thr Ser Arg Val Leu Leu Asn Val Gly Gln Glu Val Ile Ala Val
  65                  70                  75                  80
 Val Glu Glu Asn Lys Val Ser Asn Gly Leu Lys Ala Ile Arg Val Glu
                  85                  90                  95    
 Ala Val Ser Asp Lys Trp Glu Asp Asp Ser Arg Asn His Gly Ser Pro
             100                 105                 110        
 Ser Asp Cys Gly Pro Arg Val Leu Ile Gly Cys Val Thr Ser Leu Val
         115                 120                 125            
 Glu Gly Ala Gly Cys Ile Ser Gln Thr Thr Tyr Phe Ser Leu Glu Ser
     130                 135                 140                
 Val Cys Glu Gly Phe Glu Pro Cys Lys Gly Asp Trp Val Glu Ala Glu
 145                 150                 155                 160
 Tyr Arg Ile Arg Pro Gly Thr Trp Ser Ser Glu Ala Thr Ser Val Lys
                 165                 170                 175    
 Pro Leu Arg Tyr Lys Arg Val Asp Lys Val Cys Ile Ser Ser Leu Cys
             180                 185                 190        
 Gly Arg Asn Gly Val Leu Glu Glu Ser Ile Phe Phe Thr Leu Asp Ser
         195                 200                 205            
 Leu Lys Leu Pro Asp Gly Tyr Thr Pro Arg Arg Gly Asp Val Val Asn
     210                 215                 220                
 Ala Val Val Val Glu Ser Ser Gln Ser Cys Tyr Val Trp Arg Ala Leu
 225                 230                 235                 240
 Cys Met Thr Leu Val Lys Arg Arg Asp Ala Ala Pro Val His Glu Ala
                 245                 250                 255    
 Thr His Phe Tyr Gly Thr Ile Leu Leu Lys Asn Lys Gly Asp Ile Glu
             260                 265                 270        
 Val Thr Gln Leu Leu Asn Met Ser Asn Tyr Lys Glu Lys Phe Ser Thr
         275                 280                 285            
 Leu Leu Trp Leu Glu Glu Ile Tyr Ala Glu Met Glu Leu Lys Glu Tyr
     290                 295                 300                
 Asn Met Ser Gly Ile Ile Leu Arg Arg Asn Gly Asp Leu Leu Val Leu
 305                 310                 315                 320
 Glu Val Pro Gly Leu Ala Glu Gly Arg Pro Ser Leu Tyr Ala Gly Asp
                 325                 330                 335    
 Lys Leu Ile Leu Lys Thr Gln Glu Tyr Asn Gly His Ala Ile Glu Tyr
             340                 345                 350        
 Ile Ser Tyr Val Thr Glu Ile His Glu Glu Asp Val Thr Leu Lys Ile
         355                 360                 365            
 Asn Pro Glu Phe Glu Gln Ala Tyr Asn Phe Glu Pro Met Asp Val Glu
     370                 375                 380                
 Phe Thr Tyr Asn Arg
 385                



      <210> 1871
      <211> 96
      <212> PRT
      <213> Homo sapiens


      <400> 1871
 Met Ser Leu Val Pro Leu Leu Ala Ser Phe Pro Ala Gly Ala Val Leu
   1               5                  10                  15    
 His Gln Trp Thr Glu Arg Arg Leu Val Asn His Lys Gln Tyr Leu Glu
              20                  25                  30        
 Ala Lys Arg Leu Leu Lys Glu Phe Gln Ala Arg Tyr Arg Gln Leu Val
          35                  40                  45            
 Ser Gly Ser Leu Arg Thr Val Phe Gly Thr Thr Pro Leu Pro Met Ala
      50                  55                  60                
 Cys Pro Ala Leu Ser Glu Ser Gln Pro Lys Ile Gly His Phe Leu Glu
  65                  70                  75                  80
 Ile Lys Asp Glu Phe Cys Gln Glu Pro Thr Ala Ser Asp Ser Gln Gly
                  85                  90                  95    





      <210> 1872
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 1872
 Met Thr Gly Ile Leu Arg Asn Ser Leu Cys Arg Phe Arg Ala Leu Cys
   1               5                  10                  15    
 Lys Cys Ala Leu Glu Val Pro Pro Ser His Arg Arg Gln Tyr Thr Asn
              20                  25                  30        
 Thr Glu Pro Cys Leu Pro Thr Ala Ile Ser Met Gly His Leu Glu Ala
          35                  40                  45            
 Arg Glu Leu Pro Pro Val Ser Leu Gln Gly Ser Gly Pro Pro Arg Asp
      50                  55                  60                
 Val Gly Pro Glu Gly Arg Phe Glu His Val Gly Gln Ser Asp Ser Met
  65                  70                  75                  80
 Arg Thr Ser Ser Asn Pro Ala Met Ala Leu Gly Phe Ser Pro Trp Val
                  85                  90                  95    
 Phe Ser Trp Arg His Pro Ser Val Lys Asp Leu Ala Tyr Gly Ala Asp
             100                 105                 110        
 Leu Gly Phe Asp Gly Glu Arg Leu Ala Gly Asp Arg Ala Ile His Ala
         115                 120                 125            
 His Arg Gly
     130    



      <210> 1873
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1873
 Met Leu Ser Cys Arg Leu Gln Cys Ala Leu Ala Ala Leu Ser Ile Val
   1               5                  10                  15    
 Leu Ala Leu Gly Cys Val Thr Gly Ala Pro Ser Asp Pro Arg Leu Arg
              20                  25                  30        
 Gln Phe Leu Gln Lys Ser Leu Ala Ala Ala Ala Gly Lys Gln Ser Phe
          35                  40                  45            
 Gly Ala Phe Leu Gly Pro Ser Ala Pro Glu Ala Leu Glu Lys Thr Ile
      50                  55                  60                
 Lys Gly
  65    



      <210> 1874
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 1874
 Met Thr Tyr Gln His Ser Asn Gln Ala Leu Ala Gly Ala Leu Gln Ala
   1               5                  10                  15    
 Leu Met Phe Lys Ala Ile Trp Val Leu Ile Leu Ile Gln Leu Ser Lys
              20                  25                  30        
 Glu Asp Lys His Glu Ile Ile Leu Pro Thr Ser Ile Lys Gln Ala Arg
          35                  40                  45            
 Leu Asn His Ala Lys Thr Asn Leu Tyr
      50                  55        



      <210> 1875
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 1875
 Met Gln Thr Arg Arg Ile Pro Ser Val Trp Leu Gly Thr Trp Met Cys
   1               5                  10                  15    
 Asp Asn Val Leu Leu Phe Thr Val Ser Ala Val Ser Pro Thr Glu Arg
              20                  25                  30        
 Thr Ser Val Arg Ser Pro Gln Ser Val Gln Pro Thr Ser Thr Ala Ala
          35                  40                  45            
 Pro Thr His Ala Val Leu Pro Gly Gln Leu Ile Leu Thr Leu Lys Ser
      50                  55                  60                
 Gly Ile Val His Pro Asp Asn Leu His Asn His Gln Val Arg Thr Glu
  65                  70                  75                  80
 Phe Arg Leu Asn Pro Tyr Cys Leu Asp Thr Glu Thr Glu Ala Asp Lys
                  85                  90                  95    
 Asp Cys Val Ala Ser Pro Val Ser Leu Ser Cys Ser Asn Leu Gly Lys
             100                 105                 110        
 Glu His Ser Met Glu Lys Glu Gln Asp Ile His Cys Pro Ala Cys Gly
         115                 120                 125            
 Met Phe Ser Gly Arg Lys Gly Lys Glu Glu Glu Arg Glu Lys Arg Arg
     130                 135                 140                
 Glu Lys Glu Asp Glu Asn Ala Glu Ser Gln Ile Lys
 145                 150                 155    



      <210> 1876
      <211> 246
      <212> PRT
      <213> Homo sapiens


      <400> 1876
 Met Ala Arg Gly Ala Ala Leu Ala Leu Leu Leu Phe Gly Leu Leu Gly
   1               5                  10                  15    
 Val Leu Val Ala Ala Pro Gly Glu Arg Ala Glu Gly Ser Gly Tyr Pro
              20                  25                  30        
 Cys Val Leu Pro Ser Ile Tyr Pro Ser Ile Tyr Ala Ser Met His Pro
          35                  40                  45            
 Ser Ser His Ala Ser Ser Phe Tyr Pro Ser Ile His Gln Pro Ile Leu
      50                  55                  60                
 Pro Phe Ile Tyr Pro Ser Ile Arg Ser Ser Ile His Pro Ser Ile Asn
  65                  70                  75                  80
 Pro Ser Ser His Ser Phe Thr His Pro Ser Ile His Pro Cys Ile His
                  85                  90                  95    
 Pro Ser Met Arg Ala Ser Ile His Pro Phe Ile His Pro Ser Ile His
             100                 105                 110        
 Pro Ser Val Val Pro Phe Leu Tyr Pro Ser Val Asn Ala Pro Val His
         115                 120                 125            
 Pro Ser Ile His Ser Pro Phe Ile Phe Pro Ser Met His His Pro Cys
     130                 135                 140                
 Ile His Pro Phe Ser Ser Ser Ser His Ser Ser Ile Asp Thr Ser Ile
 145                 150                 155                 160
 Cys Pro Pro Ser Thr His Leu Ser Ile His Ser Pro Ile Leu Ser Ser
                 165                 170                 175    
 Ile Tyr Pro Ser Thr Ile His Pro Phe Ile Arg Ser Pro Ile His Leu
             180                 185                 190        
 Ser Ile Cys Pro Ser Ile His Leu Ser Val His Pro Ser Ile His Ser
         195                 200                 205            
 Ser Ile His Pro Ser Thr Tyr Ser Pro Thr His Pro Ser Ile His Pro
     210                 215                 220                
 Pro Asn His Pro Ser Thr Gln Pro Ser Ile His Thr Ser Ile Arg Leu
 225                 230                 235                 240
 Pro Thr His Ser Ser Thr
                 245    



      <210> 1877
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 1877
 Met Leu Leu Thr Gln Ser Leu Phe Gly Gly Leu Phe Thr Arg Thr Cys
   1               5                  10                  15    
 Met Lys Phe Cys Ala Val Thr Arg Ile Gly Gly Pro Pro Leu Gly Asp
              20                  25                  30        
 Gln Ser Leu Tyr Ser Cys Ser Leu Leu Arg Glu Lys Asp Pro Pro Met
          35                  40                  45            
 Thr Ser Gly Pro Gln Thr Asp Gln Pro Lys Glu His Val Thr Asn Phe
      50                  55                  60                
 Lys Ser Gly Cys Cys Asn Ile Ala Gly Ser Leu Val Phe Met Met Lys
  65                  70                  75                  80
 Leu Tyr Val Val Glu Val Lys Gly His Thr Lys Val Val Thr Ile Phe
                  85                  90                  95    
 Pro Asn Asp Ile Thr Val Pro Ala Ile
             100                 105



      <210> 1878
      <211> 243
      <212> PRT
      <213> Homo sapiens


      <400> 1878
 Met Ala Ala Ala Ser Ala Gly Ala Thr Arg Leu Leu Leu Leu Leu Leu
   1               5                  10                  15    
 Met Ala Val Ala Ala Pro Ser Arg Ala Arg Gly Ser Gly Cys Arg Ala
              20                  25                  30        
 Gly Thr Gly Ala Arg Gly Ala Gly Ala Glu Gly Arg Glu Gly Glu Ala
          35                  40                  45            
 Cys Gly Thr Val Gly Leu Leu Leu Glu His Ser Phe Glu Ile Asp Asp
      50                  55                  60                
 Ser Ala Asn Phe Arg Lys Arg Gly Ser Leu Leu Trp Asn Gln Gln Asp
  65                  70                  75                  80
 Gly Thr Leu Ser Leu Ser Gln Arg Gln Leu Ser Glu Glu Glu Arg Gly
                  85                  90                  95    
 Arg Leu Arg Asp Val Ala Ala Leu Asn Gly Leu Tyr Arg Val Arg Ile
             100                 105                 110        
 Pro Arg Arg Pro Gly Ala Leu Asp Gly Trp Lys Leu Cys Ser Leu Val
         115                 120                 125            
 Glu Ser His Leu Ser Asp Gln Leu Thr Leu His Val Asp Val Ala Gly
     130                 135                 140                
 Asn Val Val Gly Val Ser Val Val Thr His Pro Gly Gly Cys Arg Gly
 145                 150                 155                 160
 His Glu Val Glu Asp Val Asp Leu Glu Leu Phe Asn Thr Ser Val Gln
                 165                 170                 175    
 Leu Gln Pro Pro Thr Thr Ala Pro Gly Pro Glu Thr Ala Ala Phe Ile
             180                 185                 190        
 Glu Arg Leu Glu Met Glu His Ala Gln Lys Ala Lys Asn Pro Gln Glu
         195                 200                 205            
 Gln Lys Ser Phe Phe Ala Lys Tyr Glu Ile Ala Tyr Ala Phe Ser Val
     210                 215                 220                
 Phe Ile Pro Cys Glu Ser Cys Phe Ile Leu Phe Leu Glu Asp Ser Arg
 225                 230                 235                 240
 Asn Ile Tyr
            



      <210> 1879
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 1879
 Met Arg Arg Ala Ala Ala Leu Ser His Gly Ala Val Phe Ile Leu Leu
   1               5                  10                  15    
 Cys His Leu Trp Arg Gly Leu Pro Gly Ser Thr Ser Gln Cys Pro Gly
              20                  25                  30        
 Leu Trp Trp Phe Met Leu Leu His Pro Val Ser Arg Ser Met Pro Ser
          35                  40                  45            
 Asp Thr Ala Arg Thr Val Met Val Leu Leu Phe His Ile Tyr Asp Glu
      50                  55                  60                
 Leu Gln Glu Trp Gly Arg Thr Glu Asp Leu Asp Leu Pro Cys Asp Ser
  65                  70                  75                  80
 Ala Lys Gly Ala Asn Val Val Leu Leu Arg Pro Ser Thr Cys Gln Asp
                  85                  90                  95    
 His Leu Pro Gly Pro Ala Ser Leu His Gln His Thr Ala Glu Trp Lys
             100                 105                 110        
 Val Pro Trp Leu Arg Val Gln Thr Tyr Trp Phe Tyr Pro Thr Ala Cys
         115                 120                 125            
 Lys Val Arg Cys Gln Leu Phe Asn Pro Lys Gln Val Thr His Leu Leu
     130                 135                 140                





      <210> 1880
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 1880
 Met Leu Ser Tyr Val Phe Cys Val Ser Leu Ser Trp Val Thr Ser Ser
   1               5                  10                  15    
 Val Glu Asn Gln Leu Leu Leu Leu Ala Ala Leu Trp Arg Gly Pro His
              20                  25                  30        
 Gly Glu Lys Leu Lys Ser Leu Ala Asn Ser His Met Arg Asn Arg Ala
          35                  40                  45            
 Glu Ile Val Val Ile Thr Leu His Lys Tyr Asn Ile Ala Glu Pro Leu
      50                  55                  60                
 Glu Leu Lys Gly Ser Ser Lys Ile Tyr Gly Ser Phe Leu Gly Lys Ser
  65                  70                  75                  80
 Glu His Phe
            



      <210> 1881
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1881
 Met Ser Thr Ala Arg Ala Pro Lys Pro Cys Arg Pro Trp Cys His Cys
   1               5                  10                  15    
 Arg Leu Cys Val Arg Ser Leu Trp Gly Ser Ala Leu Leu Leu Trp Pro
              20                  25                  30        
 Lys Ser Gly Leu Glu Ser Pro Val Pro Phe Ala Gly Thr Glu Ala Ala
          35                  40                  45            
 Gly His Pro Ser Leu His Gln Pro Leu Gly Leu Gln Ala Leu Leu Glu
      50                  55                  60                
 Arg Phe Ile Phe Leu Gln Ser Glu Glu Glu Phe Phe Ser Ser Gly Asn
  65                  70                  75                  80
 Leu Ser Pro Lys Gly His Ser Cys Asp Gln Met Ala Ala Cys Arg Gly
                  85                  90                  95    
 Ala Phe Ser Ser Leu Gln Gly Arg Pro Ala Gly Gln Gln Ser Leu Leu
             100                 105                 110        
 Leu Ala Asp Ser Val Ala Arg Ser Val Leu Arg Gly Leu Trp His Leu
         115                 120                 125            
 Gly Ala Thr Glu Ala Leu Gln Ala Gln Cys Pro Cys Phe Ser Gln Gly
     130                 135                 140                
 Cys Pro Leu Arg Pro Pro Pro Gln Gly Gly Pro Phe Leu Ser Glu Lys
 145                 150                 155                 160
 Ser Trp His Phe Leu Ser His Trp Gln Cys Val Cys Ser Pro Ser Pro
                 165                 170                 175    
 Ala Val Glu Gly Glu Leu Leu Pro Ala Ala Ala Val Ala Val Ala Ala
             180                 185                 190        
 Leu Pro Gly Arg Ala Arg Leu Arg His Leu Arg Pro Gly Leu Ala Ala
         195                 200                 205            
 Arg Asn Lys Asp Gly Gly Ser Gly Ala Gly Cys Ile Tyr Phe Val Ile
     210                 215                 220                
 Phe
 225



      <210> 1882
      <211> 244
      <212> PRT
      <213> Homo sapiens


      <400> 1882
 Met Thr Glu Gly Gln Phe Gly Trp Thr Val Leu Ser Leu Gly Ala Tyr
   1               5                  10                  15    
 Met Val Gly Pro Ala Leu Ser Met Glu Ile Gln Tyr Lys Gly Tyr Trp
              20                  25                  30        
 Asp Pro Trp Leu Gln Gln Gln Val Leu Val Pro Ala Lys Cys Ser Val
          35                  40                  45            
 Gln Leu Glu Phe Lys Thr Val Leu Val Ile Leu Ser Pro Glu Ser Leu
      50                  55                  60                
 Pro Val Ser Gly Phe Tyr Phe Ala Glu Lys Glu Thr Gln Thr Gly Leu
  65                  70                  75                  80
 Gln Leu Ala Val Thr Lys Pro Leu Gln Lys Pro His Arg Gln Glu Gly
                  85                  90                  95    
 Ile Gln Gly Arg Glu Gly Ser Arg Pro Val Pro Glu Gln Gly Pro Gly
             100                 105                 110        
 Ser Ala His Val Arg Ser Ala Pro Ala Thr Gly Met Arg Gly Arg Trp
         115                 120                 125            
 Gly Arg Gly Asp Ala Gly Thr Pro Gly Thr Ala Arg Glu His Val Leu
     130                 135                 140                
 Arg Ile Ala Gly Leu Arg Glu Ala Cys Arg Gly Arg Ser Pro Leu Pro
 145                 150                 155                 160
 Pro Ala Gly Lys Gln Ala Gly Ser Thr Ser Gln Asp Asn Thr Ser Phe
                 165                 170                 175    
 Ile Ala His Ala Arg Ala Leu Ile His Gly Thr Pro Pro Val Leu Leu
             180                 185                 190        
 Lys Ile Val Leu Gly Pro Leu Gly Met Pro Ser Asn His Gln Val Glu
         195                 200                 205            
 Arg Leu Leu Glu Lys Gln Glu Arg Lys Ala Gly Pro Arg His Arg Arg
     210                 215                 220                
 Gln Asn Leu Ala His Thr Ala Gly Ala Pro Gly Ser Ala Met Pro Asn
 225                 230                 235                 240
 Gln Val Val Thr
                



      <210> 1883
      <211> 388
      <212> PRT
      <213> Homo sapiens


      <400> 1883
 Met Gly Val Ala Arg Arg Lys Phe Leu Arg Phe Phe Phe Asn Pro Leu
   1               5                  10                  15    
 His Leu Cys Ser Trp Ile Lys Asp Glu Trp Ser Leu Ile Tyr Glu Pro
              20                  25                  30        
 Ala His Val Lys Glu Asn Trp Ile Asp Pro Leu Met Arg Trp Gln Pro
          35                  40                  45            
 Glu Val Gln Glu Leu Ile Asn His Leu Glu Gly Val Ser Ala Ser Gln
      50                  55                  60                
 Ser Ser Pro Leu Lys Thr Lys Ala Lys Val Thr Glu Pro Lys Glu Phe
  65                  70                  75                  80
 Asn Leu Thr Ala Pro Arg Pro Arg Thr Ile Pro Ala Pro Glu Pro Val
                  85                  90                  95    
 Pro Val Val Ala Lys Pro Arg Pro Val Ser Val Gly Ile Leu Ser Arg
             100                 105                 110        
 His Trp Leu Ala Gly Ile Arg Pro Ser His Gly Ser Lys Gln Asn Leu
         115                 120                 125            
 Ser Lys Tyr Gln Leu Asp Gly Trp Met Gly Gly Trp Ile Ile Arg Trp
     130                 135                 140                
 Met Val Asp Gly Trp Val Asp Glu Trp Met Asp Gly Trp Met Asp Asp
 145                 150                 155                 160
 Trp Ile Ala Ala Asp His Arg Leu Phe Leu Pro Pro Leu Gln Gln Val
                 165                 170                 175    
 Pro Gln Ser Thr Tyr Gln Pro Pro Lys Glu Gln Gln Gln Leu Glu Thr
             180                 185                 190        
 Val Lys Arg Tyr Asn Arg Arg Lys Ala Glu Glu Leu Leu Leu Arg Ala
         195                 200                 205            
 Asn Ile Glu Glu Leu Arg Cys Ala Met Pro Arg Ser Cys Arg Glu Arg
     210                 215                 220                
 Val Gln Gly Ser Lys Gln Gln Leu Arg Leu Gln Phe Pro Pro Arg Ile
 225                 230                 235                 240
 Arg Lys Thr Pro Lys Leu Thr Phe Tyr Arg Pro Asp Asn Ile Leu Val
                 245                 250                 255    
 Lys Leu Asn Thr Thr Ala Ile Leu Arg Glu Gly Ala Leu Tyr Gln Arg
             260                 265                 270        
 Gln Val Glu Gln Glu Leu Gln Arg Val Asp Lys Leu Val Asp Gly Ala
         275                 280                 285            
 Gly Asp Phe Ser Glu Phe Phe Glu Trp Gln Lys Lys Met Gln Ala Lys
     290                 295                 300                
 Asp Arg Glu Glu Gln Leu Ala Ala Ser Glu Cys Arg Arg Leu Gln Gly
 305                 310                 315                 320
 Lys Leu Ser His Glu Glu Ala Val Leu Ala Arg Gln Ser Leu Met Gln
                 325                 330                 335    
 Glu Asn Lys Gln Arg Val Glu Gln Gln Lys Glu Gln Val Gly Ala Met
             340                 345                 350        
 Gln Gly Ser Trp Ala Trp Gly Ser Gln Leu Asn Cys Val Pro Thr Gly
         355                 360                 365            
 Ser Cys Arg Ala Arg Ala Gly Ser Gly Ala Glu Cys Pro Gln Arg Pro
     370                 375                 380                
 Arg Arg Ser Tyr
 385            



      <210> 1884
      <211> 66
      <212> PRT
      <213> Homo sapiens


      <400> 1884
 Met Thr Met Arg Met Ser Ser Pro Ser Trp Thr Gln Ile Leu Leu Met
   1               5                  10                  15    
 Met Arg Ile Ile Cys Ser Val Ser Met Ser Trp Arg Ser Ser Arg Tyr
              20                  25                  30        
 Glu Asn His Pro Leu Arg Ser Val Asp Thr Leu Gln Lys Ile Leu Lys
          35                  40                  45            
 Glu Glu Asp Pro Leu His Pro Ser Leu Gly Leu Tyr Ala Asn Ser Lys
      50                  55                  60                
 Thr Lys
  65    



      <210> 1885
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1885
 Met Leu Arg Ser Cys Ala Ala Cys Leu Arg Met Leu Gly Ser Leu Arg
   1               5                  10                  15    
 Pro Pro Pro Lys Lys Gln Leu Ser Pro Glu Tyr Ser Ala Pro Ser Leu
              20                  25                  30        
 Leu Asn Pro Cys Arg Glu Lys Pro Ala Asn Ser Asp Leu Leu Lys Gln
          35                  40                  45            
 Pro Ser Glu Tyr Glu Glu Asp Ser Val Ser Ile Phe Ser Thr Phe
      50                  55                  60            



      <210> 1886
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 1886
 Met Gly Cys Ala Phe Ser Ser Trp Phe His His Leu Val Leu Val Asp
   1               5                  10                  15    
 His Leu Asp Cys Leu Val Ile Asp Ala Gln Pro Ala Ile Gln Thr Asp
              20                  25                  30        
 Leu Glu Asp Val Ser Ser Val Met Ala Thr Arg Arg Thr Val Ala Val
          35                  40                  45            
 Met Val Asp His Cys Lys Glu Pro Ile Ala Leu Gln Cys Ile Leu Asp
      50                  55                  60                
 Cys Ala Tyr Phe Val Arg Leu Asp Ile Gln Leu Gln Arg Glu Lys Trp
  65                  70                  75                  80
 Leu Gln Ser Gly Arg Phe Phe Cys Thr Leu Leu Val Asn His Arg Pro
                  85                  90                  95    
 Asp Val Ala Thr Lys Asn Val Val Ile Gly Val
             100                 105        



      <210> 1887
      <211> 183
      <212> PRT
      <213> Homo sapiens


      <400> 1887
 Met Gly Ser Arg Leu Leu Cys Trp Val Leu Leu Cys Leu Leu Gly Ala
   1               5                  10                  15    
 Gly Pro Val Lys Ala Gly Val Thr Gln Thr Pro Arg Tyr Leu Ile Lys
              20                  25                  30        
 Thr Arg Gly Gln Gln Val Thr Leu Ser Cys Ser Pro Ile Ser Gly His
          35                  40                  45            
 Arg Ser Val Ser Trp Tyr Gln Gln Thr Pro Gly Gln Gly Leu Gln Phe
      50                  55                  60                
 Leu Phe Glu Tyr Phe Ser Glu Thr Gln Arg Asn Lys Gly Asn Phe Pro
  65                  70                  75                  80
 Gly Arg Phe Ser Gly Arg Gln Phe Ser Asn Ser Arg Ser Glu Met Asn
                  85                  90                  95    
 Val Ser Thr Leu Glu Leu Gly Asp Ser Ala Leu Tyr Leu Cys Ala Ser
             100                 105                 110        
 Ser Leu Ala Gln Pro Tyr Lys Ala Asn His Ile Leu Cys Thr Asn Leu
         115                 120                 125            
 Pro Gly Pro Met Trp Ser Asn Leu Ser Pro Asp Ile Ser Leu Arg Gly
     130                 135                 140                
 Cys Ala Gly Gln Glu Gly Cys Met Glu Leu Leu Ser Leu Ser Leu Ser
 145                 150                 155                 160
 Met Gly Glu Gln Gly Arg Ser Gly Leu Gln Lys Glu Tyr Leu Glu Lys
                 165                 170                 175    
 Asp Cys Thr Arg Arg Ile Gly
             180            



      <210> 1888
      <211> 217
      <212> PRT
      <213> Homo sapiens


      <400> 1888
 Met Ser Leu Ile Gln Ala Val Thr Met Val Thr Val Phe Pro Arg Leu
   1               5                  10                  15    
 Ala Leu Leu Val Gly Pro Gln Leu Ala Arg Thr Cys Cys Leu Ala His
              20                  25                  30        
 Cys Cys Pro Pro Cys His Ser His Glu Ser Val Asn Ile Tyr Pro Arg
          35                  40                  45            
 Asp Phe Leu Phe Gln Glu Leu Lys Ala Leu Arg Ile Phe Glu Val Leu
      50                  55                  60                
 Gly Ala Val Gly Leu Arg Val Gly Arg Asp Leu Gln Asp His Arg Ser
  65                  70                  75                  80
 Ser Thr Ser Tyr Pro Val Ala Ser Leu Arg Tyr Gly Tyr Leu Ala Phe
                  85                  90                  95    
 Ala Ser Leu Leu Lys Asp Gly Pro Gly Tyr Trp Val Lys Ile His His
             100                 105                 110        
 Leu Glu Tyr Thr Asp Gly Gly Ile Leu Asp Pro Asp Asp Val Leu Ala
         115                 120                 125            
 Asp Val Val Glu Asp Lys Asp Lys Ser Ser Trp Leu Thr Tyr Leu Glu
     130                 135                 140                
 Met Glu Val Pro Ser Val Lys Thr Glu Glu Pro Gly Thr Thr Ile Glu
 145                 150                 155                 160
 Lys Arg Gly Phe Arg Gly Ser Leu Leu Thr Val Leu Asn Tyr Leu Ser
                 165                 170                 175    
 Asp His Arg Lys Gly Ile Asn Ser Phe Pro Ile Ala Leu Arg Asn Arg
             180                 185                 190        
 Ala Ser Gly Val Ser Arg Lys Ser Phe Ser Ala Glu Tyr Asn Glu Gln
         195                 200                 205            
 Leu Leu Asn Glu Ala His Ala Ala Phe
     210                 215        



      <210> 1889
      <211> 305
      <212> PRT
      <213> Homo sapiens


      <400> 1889
 Met Gly Gly Thr Leu Ala Trp Thr Leu Leu Leu Pro Leu Leu Leu Arg
   1               5                  10                  15    
 Glu Ser Asp Ser Leu Glu Pro Ser Cys Thr Val Ser Ser Ala Asp Val
              20                  25                  30        
 Asp Trp Asn Ala Glu Phe Ser Ala Thr Cys Leu Asn Phe Ser Gly Leu
          35                  40                  45            
 Ser Leu Ser Leu Pro His Asn Gln Ser Leu Arg Ala Ser Asn Val Ile
      50                  55                  60                
 Leu Leu Asp Leu Ser Gly Asn Gly Leu Arg Glu Leu Pro Val Thr Phe
  65                  70                  75                  80
 Phe Ala His Leu Gln Lys Leu Glu Val Leu Asn Val Leu Arg Asn Pro
                  85                  90                  95    
 Leu Ser Arg Val Asp Gly Ala Leu Ala Ala Arg Cys Asp Leu Asp Leu
             100                 105                 110        
 Gln Ala Asp Cys Asn Cys Ala Leu Glu Ser Trp His Asp Ile Arg Arg
         115                 120                 125            
 Asp Asn Cys Ser Gly Gln Lys Pro Leu Leu Cys Trp Asp Thr Thr Ser
     130                 135                 140                
 Ser Gln His Asn Leu Ser Ala Phe Leu Glu Val Ser Cys Ala Pro Gly
 145                 150                 155                 160
 Leu Ala Ser Ala Thr Ile Gly Ala Val Val Val Ser Gly Cys Leu Leu
                 165                 170                 175    
 Leu Gly Leu Ala Ile Ala Gly Pro Val Leu Ala Trp Arg Leu Trp Arg
             180                 185                 190        
 Cys Arg Val Ala Arg Ser Arg Glu Leu Asn Lys Pro Trp Ala Ala Gln
         195                 200                 205            
 Asp Gly Pro Lys Pro Gly Leu Gly Leu Gln Pro Arg Tyr Gly Ser Arg
     210                 215                 220                
 Ser Ala Pro Lys Pro Gln Val Ala Val Pro Ser Cys Pro Ser Thr Pro
 225                 230                 235                 240
 Asp Tyr Glu Asn Met Phe Val Gly Gln Pro Ala Ala Glu His Gln Trp
                 245                 250                 255    
 Asp Glu Gln Gly Ala His Pro Ser Glu Asp Asn Asp Phe Tyr Ile Asn
             260                 265                 270        
 Tyr Lys Asp Ile Asp Leu Ala Ser Gln Pro Val Tyr Cys Asn Leu Gln
         275                 280                 285            
 Ser Leu Gly Gln Ala Pro Met Asp Glu Glu Glu Tyr Val Ile Pro Gly
     290                 295                 300                
 His
 305



      <210> 1890
      <211> 97
      <212> PRT
      <213> Homo sapiens


      <400> 1890
 Met Arg Pro Leu Leu Cys Ala Leu Thr Gly Leu Ala Leu Leu Arg Ala
   1               5                  10                  15    
 Ala Gly Ser Leu Ala Ala Ala Glu Pro Phe Ser Pro Pro Arg Gly Asp
              20                  25                  30        
 Ser Ala Gln Ser Thr Ala Cys Asp Arg His Met Ala Val Gln Arg Arg
          35                  40                  45            
 Leu Asp Val Met Glu Glu Met Val Glu Lys Thr Val Asp His Leu Gly
      50                  55                  60                
 Thr Glu Val Lys Gly Leu Leu Gly Leu Leu Glu Glu Leu Ala Trp Asn
  65                  70                  75                  80
 Leu Pro Pro Gly Pro Phe Ser Pro Ala Pro Asp Leu Leu Gly Asp Gly
                  85                  90                  95    
 Phe
    



      <210> 1891
      <211> 176
      <212> PRT
      <213> Homo sapiens


      <400> 1891
 Met Ser Gln Arg Gly Leu Glu Ala Ser Val Leu Leu Ala Leu Cys Glu
   1               5                  10                  15    
 Ala Ala Ala Val Cys Pro Gly Val Ser Ala Ala Leu Gly Leu Trp Lys
              20                  25                  30        
 Gly Asn Gln Gly Ser Ala Glu Ala Val Cys Pro Ala Leu His Gln Gly
          35                  40                  45            
 Glu Gln Gly Gln Leu Ala Glu Gly Leu Gln Ala Leu Cys Cys Ser Glu
      50                  55                  60                
 Arg Gln Leu Asp Ile Arg Asp Ala Asp Gly Pro Thr Ser Pro Arg Ser
  65                  70                  75                  80
 Pro Ser Ser Pro Val Ser Arg Val Val Tyr Asn Gly Lys Arg Thr Ser
                  85                  90                  95    
 Ser Pro Arg Ser Pro Pro Ser Ser Ser Glu Ile Phe Thr Pro Ala His
             100                 105                 110        
 Glu Glu Asn Val Arg Phe Ile Tyr Glu Ala Trp Gln Gly Val Glu Arg
         115                 120                 125            
 Asp Leu Arg Gly Gln Val Pro Gly Gly Glu Arg Gly Leu Val Glu Glu
     130                 135                 140                
 Tyr Val Glu Lys Val Pro Asn Pro Ser Leu Lys Thr Phe Lys Pro Ile
 145                 150                 155                 160
 Asp Leu Ser Asp Leu Lys Arg Arg Ser Thr Gln Asp Ala Lys Lys Ser
                 165                 170                 175    





      <210> 1892
      <211> 306
      <212> PRT
      <213> Homo sapiens


      <400> 1892
 Met Val Ser Asn Ser Trp Leu Gln Ala Ile Leu Leu Pro Leu Ser Pro
   1               5                  10                  15    
 Lys Ala Leu Gly Leu Gln Ala Lys Ile Gln Thr Cys Leu Leu Lys Leu
              20                  25                  30        
 Thr Leu Asn Thr Ser Arg Thr Lys Ala Ile Asp Gly Asn Tyr Leu Asn
          35                  40                  45            
 Ser Asn Leu Ser Ser Asp Ser Tyr His Leu Gly Asp Leu Lys Glu Met
      50                  55                  60                
 Ala Glu Leu Ala Asp Gly Gln Gly Lys Gly Leu Gly Glu Tyr Arg Thr
  65                  70                  75                  80
 Gln Glu Ile Pro Ser Pro Cys Asp Val Gly Ser Arg Thr Pro Gly Ala
                  85                  90                  95    
 Lys Trp Arg Cys Ala Ser Cys Pro Thr Leu Glu Lys Ala Gln Arg Lys
             100                 105                 110        
 Gln Ile Pro Pro Phe Ala Ala Gly Gly Phe Ser Ser Pro Arg Ala Thr
         115                 120                 125            
 Val Gln Leu Leu Leu Ala Ser Ser Lys Thr Asn Ile Ser Met Asp Gly
     130                 135                 140                
 Arg Ser Arg Thr Gln Gly Gly Glu Gly His Leu Ser Gly Arg Lys Glu
 145                 150                 155                 160
 Gly Arg Gly Leu Ala Tyr Leu Gly Arg Lys Trp Leu Ser Leu Arg Arg
                 165                 170                 175    
 Pro Pro Gly Leu Arg Phe Pro Glu Phe Ser Thr Gly Ser Gly Arg Arg
             180                 185                 190        
 Pro Gln Pro Pro Arg Ala Glu Val Thr Arg Leu His Gly Ala Pro Lys
         195                 200                 205            
 Leu His Phe Pro Glu Phe Leu Glu Lys Leu Ser Thr Leu Cys Leu Pro
     210                 215                 220                
 Arg Thr Gln Val Gln Gly Ala Lys Arg Arg Ala Trp Ile Ile Phe His
 225                 230                 235                 240
 Met Cys Arg Ser Gln Arg Asn Ser Leu Thr Leu Pro Ser Trp Asn Arg
                 245                 250                 255    
 Asn Ala Ser Lys Gly Arg Glu Leu Leu Tyr Ile Phe Leu Cys Phe Pro
             260                 265                 270        
 Arg Arg Thr Val His Glu Arg Arg Leu Phe Gly Ala Cys Val Ser Asp
         275                 280                 285            
 Pro Val Asp Leu Leu Asp Asn Ser Arg Asn Phe Leu Gln Gly Ser Thr
     290                 295                 300                
 Ser Pro
 305    



      <210> 1893
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1893
 Met Arg Asn Leu Leu Leu Ile Pro Ala Leu Ser Leu Gln Thr Glu Gly
   1               5                  10                  15    
 Ser Glu Lys Ile Ala Asp Arg Phe Ser Lys Lys Thr Gln Thr Cys Lys
              20                  25                  30        
 Asn Ser Arg Glu Arg Lys Ile Leu Lys Ala Ser His Ser Leu Gly Ala
          35                  40                  45            
 Ser Ser Ser Lys Cys Val Val Met Val Ser Glu Gly Phe Gly Glu Lys
      50                  55                  60                
 Gln Asn Ser Arg Thr Tyr Leu Ile Lys Arg Leu Gln Phe Leu Leu Ser
  65                  70                  75                  80
 Pro His Lys Asp Ser Leu Asn Leu Leu Pro Cys Leu Lys Lys His Lys
                  85                  90                  95    
 Ile Leu Thr Thr Ser Gln Ile Ser Pro Thr Trp His Asp Asn Lys Arg
             100                 105                 110        
 Pro Thr Lys Leu Ser Arg Tyr Val Pro Lys
         115                 120        



      <210> 1894
      <211> 118
      <212> PRT
      <213> Homo sapiens


      <400> 1894
 Met Ala Val Val Leu Val Ile Val Val Glu Ala Gly Met Val Val Val
   1               5                  10                  15    
 Asp Gln Asp Met Glu Thr Lys Val Val Asp Met Val Ala Val Leu Glu
              20                  25                  30        
 Asp Met Met Val Thr Met Lys Glu Glu Ile Leu Thr Val Val Thr Met
          35                  40                  45            
 Val Val Tyr Phe Arg Asn Arg Gly Pro His Leu Leu Lys Asp Lys Glu
      50                  55                  60                
 Asn Ser Ser Leu Ser Lys Pro Thr Val Asp Ile Glu Glu His Glu His
  65                  70                  75                  80
 Thr Trp Pro Lys Cys Ile Leu Gly Gly Gly Pro Ala Tyr Thr Lys Ala
                  85                  90                  95    
 Leu Lys Pro Glu Leu Thr Trp Tyr Leu Gln Glu Glu Gln Gly Leu Gln
             100                 105                 110        
 Ser Gln Glu Trp Asn Gly
         115            



      <210> 1895
      <211> 228
      <212> PRT
      <213> Homo sapiens


      <400> 1895
 Met Ala Ser Cys Leu Gln Leu Leu Leu Cys Phe Ser Gly Val Ser Trp
   1               5                  10                  15    
 Leu Ala Cys Leu Gly Cys Leu Gly Gly Thr Phe Ser Ser Cys His Leu
              20                  25                  30        
 Pro Ser Leu Gln Ile Leu Gln Pro Ser Lys Lys Asp Thr Glu Glu Lys
          35                  40                  45            
 Ser Leu Arg Trp Lys Val Asp Gly Ala Lys Gly Ile Val Lys Val Asn
      50                  55                  60                
 Val Pro Phe Ser Tyr Pro Ser Ser Pro Lys Ser Lys Ala Glu Leu Ile
  65                  70                  75                  80
 Ala Leu Thr Gln Gly Leu Thr Leu Pro Lys Gly Leu His Ile Asn Ile
                  85                  90                  95    
 Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Leu His His His Ser Val
             100                 105                 110        
 Ile Trp Ala Glu Arg Gly Phe Leu Thr Thr Gln Gly Ser Ser Ile Ile
         115                 120                 125            
 Asn Ala Ser Leu Ile Lys Thr Leu Leu Lys Ala Ala Leu Phe Pro Lys
     130                 135                 140                
 Glu Ala Gly Val Ile His Cys Lys Gly His Gln Lys Ala Ser Asp Ala
 145                 150                 155                 160
 Ile Ala Gln Gly Asn Thr Tyr Ala Asp Lys Ser Asp Asn Gly Leu Ala
                 165                 170                 175    
 Phe Thr Ser Gln Ile Thr Gln Ala Val Ser Gln Ala Leu Val Ile Gln
             180                 185                 190        
 Trp Lys Leu His Ile Pro Tyr His Pro Gln Ser Ser Gly Lys Thr Gly
         195                 200                 205            
 Pro Val Lys Pro Pro Gln Thr Phe His Ile Ser Lys Leu Pro Pro Ser
     210                 215                 220                
 Ser Thr Leu Thr
 225            



      <210> 1896
      <211> 69
      <212> PRT
      <213> Homo sapiens


      <400> 1896
 Met Ala Trp Gly Ala Phe Leu Val Asp Val Leu Gln Phe Leu Ser Asn
   1               5                  10                  15    
 Ser Ala Ala Glu Ala Leu Leu Gly Asp Thr Pro Ser Ser Gly Ile Tyr
              20                  25                  30        
 Phe Pro Asp Ser Gln Phe Ser Val Asp Thr His Ala Asp Glu Pro Lys
          35                  40                  45            
 Asn Val Cys Leu Ser Glu Ile Asn Thr Ala Phe Leu Pro Ala Ala His
      50                  55                  60                
 Arg Val Ala Gly Thr
  65                



      <210> 1897
      <211> 235
      <212> PRT
      <213> Homo sapiens


      <400> 1897
 Met Pro Cys Gly Leu Ser Ala Leu Ile Met Cys Pro Lys Gly Met Val
   1               5                  10                  15    
 Ala Val Val Val Ala Val Asp Asp Gly Asp Ser Gln Ala Leu Ala Val
              20                  25                  30        
 Pro Leu Thr Leu Arg Val Pro Arg Gly Gly Gly Ala Gly Thr Leu Ala
          35                  40                  45            
 His Arg Gln Asp Lys Asp Ala Gln Ala Ala Leu Gly Ser Gln Leu Ile
      50                  55                  60                
 Pro Phe Asn Ser Ser Asn Arg Thr Gln Leu Arg Lys Ser Val Arg Ser
  65                  70                  75                  80
 Arg Thr Ala Gly Lys Gln Ala Val Pro Gln Asp Asn Gly Gln Pro Lys
                  85                  90                  95    
 Glu Thr Val Ser Met Leu Pro Ser Arg Glu Arg Thr Pro Asp Arg Gly
             100                 105                 110        
 Gly Ser Cys Arg Leu Pro Gln Leu Met Arg Gln Pro Arg Arg Asn Ser
         115                 120                 125            
 Pro Ser His Pro Leu Thr Ser His Pro Ser Pro Cys Pro Ala Pro Gly
     130                 135                 140                
 Val Trp Lys His Gln Ala Ser Pro Cys Phe Arg Gly Thr Val Ser Val
 145                 150                 155                 160
 Leu Val Arg Phe His Ala Ala Asp Lys His Ile Pro Glu Thr Gly Lys
                 165                 170                 175    
 Lys Lys Arg Phe Asn Gly Leu Thr Val Pro His Gly Trp Gly Gly Leu
             180                 185                 190        
 Thr Ile Met Ala Glu Gly Asp Glu Glu Gln Val Thr Ser Tyr Met Asp
         195                 200                 205            
 Gly Ser Arg Gln Lys Glu Ser Leu Cys Arg Glu Thr Pro Ile Phe Lys
     210                 215                 220                
 Thr Ile Arg Ser His Glu Thr Tyr Ser Leu Leu
 225                 230                 235



      <210> 1898
      <211> 261
      <212> PRT
      <213> Homo sapiens


      <400> 1898
 Met Ala Leu Leu Val Leu Ala Gly Leu Ala Leu Ala Gly Thr Ala Pro
   1               5                  10                  15    
 Thr Ala Gln Gln Thr Ala Phe Ser Ser Asp Gly Ala Ser Thr Pro Cys
              20                  25                  30        
 Lys Leu Thr Val Asn Phe Arg Arg Ala Asp Phe Leu Pro Asn Val Leu
          35                  40                  45            
 Glu Asp Pro Ala Phe Ser Ala Val Ile His Asp Lys Leu Gln Val Pro
      50                  55                  60                
 Asn Thr Ile Arg Lys Ala Trp Asn Asp Arg Asp Asn Arg Cys Asp Ile
  65                  70                  75                  80
 Cys Ala Thr His Leu Asn Gln Leu Lys Gln Glu Ala Ile Gln Met Val
                  85                  90                  95    
 Leu Thr Leu Glu Gln Ala Ala Gly Ser Glu His Tyr Asp Ala Ser Pro
             100                 105                 110        
 Cys Ser Pro Pro Pro Leu Ser Asn Ile Pro Thr Leu Val Gly Ser Arg
         115                 120                 125            
 His Val Gly Gly Leu Gln Gln Pro Arg Asp Trp Ala Phe Val Pro Ala
     130                 135                 140                
 Pro Cys Ala Thr Ser Asn Tyr Thr Gly Phe Ala Asn Lys His Gly Ser
 145                 150                 155                 160
 Lys Pro Ser Ser Leu Gly Val Ser Asn Gly Ala Glu Lys Lys Ser Gly
                 165                 170                 175    
 Ser Pro Thr His Gln Ala Lys Val Ser Leu Gln Met Ala Thr Ser Pro
             180                 185                 190        
 Ser Asn Gly Asn Ile Leu Asn Ser Val Ala Ile Gln Ala His Gln Tyr
         195                 200                 205            
 Leu Asp Gly Thr Trp Ser Leu Ser Arg Thr Asn Gly Val Thr Leu Tyr
     210                 215                 220                
 Pro Tyr Gln Gly Cys Gly Lys Gln Gln Arg Ala Leu Thr Val Thr Gly
 225                 230                 235                 240
 Met Glu Arg Arg Pro Arg Ser Arg Val Tyr Tyr Ser Glu Lys Ile Val
                 245                 250                 255    
 Gly Thr Tyr Ser Lys
             260    



      <210> 1899
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 1899
 Met Lys Met Ser Leu Leu His Thr Gly Pro Leu Ser Lys Leu Leu Leu
   1               5                  10                  15    
 Leu Thr Gly Ile Ile Ser Leu Tyr Asp Cys Ile Phe Lys Arg Arg Leu
              20                  25                  30        
 Asp Tyr Asp Gln Lys Leu His Arg Asp Asp Arg Glu His Ala Lys Ser
          35                  40                  45            
 Leu Gly Leu His Val Asn Glu Glu Glu Gln Glu Arg Pro Val Gly Val
      50                  55                  60                
 Leu Thr Ser Ser Val Tyr Gly Lys Arg Ile Asn Gln Pro Ile Glu Pro
  65                  70                  75                  80
 Leu Asn Arg Asp Phe Gly Arg Ala Asn His Val Gln Ala Asp Phe Tyr
                  85                  90                  95    
 Arg Lys Asn Asp Ile Pro Ser Leu Lys Glu Pro Gly Phe Gly His Ile
             100                 105                 110        
 Ala Pro Ser
         115



      <210> 1900
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1900
 Met Pro Arg Met Arg Leu Phe His Leu Pro Ile Met Ala Ala Ala Cys
   1               5                  10                  15    
 Ala Pro Leu Leu Ser Arg Val Val Val Ala Gly Gln Ser Gln Ser Pro
              20                  25                  30        
 Pro Arg Gly Asp Gly Ala Val Ala Ile Thr Gly Leu Thr Val Asp Gln
          35                  40                  45            
 Tyr Gly Met Leu Tyr Lys Val Ala Val Pro Pro Ala Thr Phe Ser Pro
      50                  55                  60                
 Thr Gly Leu Pro Ser Val
  65                  70



      <210> 1901
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 1901
 Met Leu Gly Thr Val Leu Leu Leu Ala Leu Leu Pro Gly Ile Thr Thr
   1               5                  10                  15    
 Leu Pro Ser Gly Pro Pro Ala Gly Ser Gly Gly His Leu Ala Trp Val
              20                  25                  30        
 Pro Gly Ala Leu Thr Arg Ser Phe Pro Val Leu Asp Leu Asn Val Asp
          35                  40                  45            
 Trp Ala Arg Cys Gly Pro Pro Ser Leu Lys Ala Ile Leu Cys Gly Gln
      50                  55                  60                
 Gly Pro Ala Asp Pro Ser Thr Ser Pro Glu Val Phe Asn Ser Pro Gln
  65                  70                  75                  80
 Ala Val Ala Pro Gly Asp Pro Arg Ala Ala Ala Pro Ala Gln Leu Pro
                  85                  90                  95    
 Ser Ala Arg Gly Arg Leu Gly Pro His His Lys Gln Leu Ile Val Thr
             100                 105                 110        
 Leu Val Lys Val Ser Glu Val Leu Gly Gly Arg Pro Gly Pro Arg Ser
         115                 120                 125            
 Pro Leu Ala Gly Ser Trp Val Ala Lys Trp Gly Gly Gly Leu Cys His
     130                 135                 140                
 Ala Pro Gly Pro Leu Trp Gly Trp Pro Pro Pro Ser Ser Tyr Leu Lys
 145                 150                 155                 160
 Lys Gly Arg Ser Val Leu Thr Ile Ser Asn Ser His Pro Ala Lys Ser
                 165                 170                 175    
 Thr Gly Leu Ala Val Pro Ser Gly
             180                



      <210> 1902
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1902
 Met Ser Arg Cys Leu Pro Ala Leu Ile Asn Lys Leu Tyr Ala Leu Ser
   1               5                  10                  15    
 Phe Ser Leu Tyr Leu Arg Ile Ile Tyr Tyr Phe Ile Val His Val Leu
              20                  25                  30        
 Met Gln Gln Thr Gln Gly Ile Thr Gly Lys Lys Lys Ile Thr Gly Ser
          35                  40                  45            
 Asp Leu Ser Phe Pro His Ser Lys Arg Pro Lys His Phe Asn Ser Tyr
      50                  55                  60                
 Val Phe Asn Tyr Ser Leu Asp Ser Thr Val Ala Gly Tyr Leu Phe Leu
  65                  70                  75                  80
 Asp Ser Arg Gly Lys Glu Lys Cys Phe Tyr Leu Thr Asn Ala Thr Ser
                  85                  90                  95    
 Cys Gln His Phe Ser Ser His Thr Thr Tyr Ser Thr Asn Thr Tyr Tyr
             100                 105                 110        
 Cys Tyr Gly Lys Gly Glu Lys Leu Lys Arg Lys Val Ser Gln Leu Ala
         115                 120                 125            
 Lys Gly Leu Arg His Ser Arg Pro Val Asp Ala Ala Leu Leu Trp Pro
     130                 135                 140                
 Ala Gly Val Ile Met Lys Pro Gly Ala Thr Gly Glu Ser Asp Leu Ala
 145                 150                 155                 160
 Glu Val Leu Pro Gln His Lys Phe Asp Ser Lys Ser Leu Glu Ala Tyr
                 165                 170                 175    
 Leu Asn Gln His Leu Ser Gly Phe Gly Ala Glu Arg Glu Ala Thr Leu
             180                 185                 190        
 Thr Ile Ala Gln Tyr Ser Gln Trp Thr His Pro Thr Gly Met Ser Cys
         195                 200                 205            
 Tyr Cys Arg Pro Ser Glu Phe Asp Ala Gly Gly Phe Pro Ile Gly Gly
     210                 215                 220                
 Arg
 225



      <210> 1903
      <211> 414
      <212> PRT
      <213> Homo sapiens


      <400> 1903
 Met Pro Arg Ser Cys Cys Ser Arg Ser Gly Ala Leu Leu Leu Ala Leu
   1               5                  10                  15    
 Leu Leu Gln Ala Ser Met Glu Val Arg Gly Trp Cys Leu Glu Ser Ser
              20                  25                  30        
 Gln Cys Gln Asp Leu Thr Thr Glu Ser Asn Leu Leu Arg Val Pro Ala
          35                  40                  45            
 Glu Glu Ile Thr Tyr Glu Thr Leu Lys Lys Ala Ile Ala Trp Pro Pro
      50                  55                  60                
 His Val Asn Pro Trp Lys Ile Gln Glu Pro His Arg Val Gly Ser Leu
  65                  70                  75                  80
 Gly Ala Ala Pro Thr Gly Thr His Gly Gln Arg Ser Leu Thr Arg Arg
                  85                  90                  95    
 Gly Glu Ala Pro Glu Pro Val Arg Gly Val Gln Val Ala Val Gly Gly
             100                 105                 110        
 Lys Gly Lys Gly Pro Ala Ile Ser Ser Trp Gln Arg Gln Gln Gln Pro
         115                 120                 125            
 Leu His Ser Glu Phe Leu Asn Ile Leu Leu Pro Pro Gln Leu Pro Pro
     130                 135                 140                
 Ala Cys Gln Met Pro Arg Cys Glu Leu Phe Ser Ile Pro Ser Pro Leu
 145                 150                 155                 160
 Gly Ala Glu His Ala Pro Gly Pro Gly Met Gln His Asp Phe Val Ala
                 165                 170                 175    
 Ala Ser Leu Thr Asp Thr Ser Ser Ala Ser Met Pro Val Asn Gly Pro
             180                 185                 190        
 Glu Asn Leu Leu Gln Ala Ser Ser Gln Lys Lys Phe Leu Val Leu Ala
         195                 200                 205            
 Trp Trp Pro Phe Ala Asp Thr Val Ser Ser Phe Phe Lys Asn Ser Lys
     210                 215                 220                
 Leu Gly Ala Gln Phe Val Lys Phe Ala Asn Ile Glu Glu Asp Thr Pro
 225                 230                 235                 240
 Ser Tyr His Arg Ser Tyr Asp Phe Phe Val Ser Arg Phe Ser Glu Met
                 245                 250                 255    
 Cys His Ser Ser His Asp Asp Leu Glu Ile Lys Thr Lys Leu Asn Gln
             260                 265                 270        
 Tyr Phe His Pro Ser Leu Leu Ser Ile Cys Asp Tyr Arg Tyr Val Cys
         275                 280                 285            
 Ile Ala Met Glu Ala Leu Asp Gln Leu Leu Met Ala Cys His Cys Gln
     290                 295                 300                
 Ser Ile Asn Leu Phe Val Glu Ser Phe Leu Lys Met Val Ala Lys Leu
 305                 310                 315                 320
 Leu Glu Ser Glu Lys Pro Asn Leu Gln Ile Leu Gly Thr Asn Ser Asp
                 325                 330                 335    
 Arg Arg Phe Gly Arg Thr Lys Gln Ala Ser Glu Glu Leu Val Gly Val
             340                 345                 350        
 Ser Ala Pro Val Pro Ala Leu Arg Val Ala Ala Gly Pro Pro Gly Pro
         355                 360                 365            
 Ala Val Trp Leu Asp Gly Phe Arg Ala Ala Trp Pro Gln Arg Leu Leu
     370                 375                 380                
 Ala Ile Glu His Pro Ile Gly Lys Gln Thr Phe Gln Glu Ser Thr Arg
 385                 390                 395                 400
 Asp Leu Leu Ala Phe Glu Thr Gly Leu Gly Val Ile Asp Trp
                 405                 410                



      <210> 1904
      <211> 123
      <212> PRT
      <213> Homo sapiens


      <400> 1904
 Met Thr Glu Ser Arg Leu Val Asp Arg Tyr Tyr Ser Phe Leu Leu Leu
   1               5                  10                  15    
 Leu Val Phe Val Phe Ser Leu Cys Gly Asp Phe Leu Phe His Ser Asn
              20                  25                  30        
 Asp Ser Ala His Leu Ser Gly Leu His Asn Asp Thr Ile Leu Lys Val
          35                  40                  45            
 Gly Ser Leu Lys Leu Arg Arg Gln Cys Arg Thr Lys Gln Lys Leu Asn
      50                  55                  60                
 His Lys Glu Met Glu Asp Leu Asn Lys Pro Ile Met Ser Asn Glu Ile
  65                  70                  75                  80
 Lys Ala Met Ile Lys Ser Phe Pro Pro Lys Lys Ser Pro Glu Ser Asp
                  85                  90                  95    
 Gly Phe Thr Val Glu Phe Gln Gln Ile Tyr Glu Glu Glu Val Ile Pro
             100                 105                 110        
 Ile Leu Phe Gln Leu Phe Lys Lys Ile Glu Glu
         115                 120            



      <210> 1905
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 1905
 Met Ala Lys Leu Glu Ala Phe Thr Met Phe Pro Ser Val Leu Leu Ala
   1               5                  10                  15    
 Leu Leu Gln Met Asn Lys Gly Met Ile Leu Asp Lys Arg Ile Asn Val
              20                  25                  30        
 Gly Ile Glu His Ile Lys His Ser Gly Ser Gln Asp Ser Phe Leu Lys
          35                  40                  45            
 His Val Lys Glu Asn Asp Gln Lys Lys Lys Pro Lys Arg Arg Leu Val
      50                  55                  60                
 Ser Val Cys
  65        



      <210> 1906
      <211> 149
      <212> PRT
      <213> Homo sapiens


      <400> 1906
 Met Arg Arg Val Ile His Ile Leu Leu Ser Pro Ala Phe Leu Gln Thr
   1               5                  10                  15    
 Arg Ser Asp Lys Gln Gly Arg Asp Thr Met Tyr Phe Leu Gly Arg Arg
              20                  25                  30        
 Glu Asp Asp Asn Leu Gly Pro Leu Glu Val Gln His Phe Pro Gln Thr
          35                  40                  45            
 Leu Leu Gln Ala Tyr Ser Val Leu Gly Pro Val Leu Ser Pro Ala Glu
      50                  55                  60                
 Trp Glu Thr Pro Val Trp Gly Gln Glu Glu Pro Ser Ala Leu Asn Gly
  65                  70                  75                  80
 Arg Gly Arg Thr His Pro Arg Pro Ser Pro Met Phe Glu Gly Ile Val
                  85                  90                  95    
 His Asp Gly Phe Glu His Gln Thr Val Ala Asp Leu Gly Arg Ala Ser
             100                 105                 110        
 Glu Val Glu His Phe Asn Gly Leu Gln Arg Arg Glu Leu Gln Gln Val
         115                 120                 125            
 Lys Arg Gln Tyr Pro Val Lys Leu Ser Gly Gln Pro Glu Gly Pro Val
     130                 135                 140                
 Pro Gly Lys Gly Thr
 145                



      <210> 1907
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1907
 Met Ala Thr Ile Val Cys Leu Leu Thr Met Phe Thr Gln Gly Leu Arg
   1               5                  10                  15    
 Val Leu Gln Ser Ser Asp Ile Glu Ser Arg Trp Gln Ala Pro Pro Trp
              20                  25                  30        
 Pro Arg Val Arg Gln Asp Met Leu Ser Arg Arg His Tyr Leu Glu Leu
          35                  40                  45            
 Gly Thr Ser Gly Ile Phe Leu Val Leu His Tyr Thr Met Thr Glu Leu
      50                  55                  60                
 Thr Pro Lys Leu Lys Val Gly Ser Ser Leu Ser Gln Val Pro Asp Leu
  65                  70                  75                  80
 Leu Thr Leu Thr Ile Cys Thr Cys Tyr Asn Arg Val Lys Glu His Gly
                  85                  90                  95    
 Val Ala Lys Arg Lys Ser Ser Tyr Thr Val Glu Gln Leu Glu Gln Val
             100                 105                 110        
 Phe Ala Gln Ala Gly Trp Asp Ala Gln Pro Cys Gln Thr Val Leu Leu
         115                 120                 125            
 Asn Ser Ser Ser Leu Tyr Gln Glu Leu Glu Ser Asp Gly Gly Thr Met
     130                 135                 140                
 Glu Asp Tyr Ser Phe Thr Gly Val Leu Gly Thr Gln Ser Gln Asp Leu
 145                 150                 155                 160
 His Gly Tyr Pro Thr Asp Gln Glu Ser Gln Arg Glu Asn
                 165                 170            



      <210> 1908
      <211> 111
      <212> PRT
      <213> Homo sapiens


      <400> 1908
 Met Leu Ser Thr Cys Lys Val Leu Ala Ala Ala His Val Thr Ala Gln
   1               5                  10                  15    
 Val Leu Ala Ala Ala Arg Phe Thr Leu Leu Pro Ala Asp Arg Pro Lys
              20                  25                  30        
 Ser Ser Pro Ala Trp Ala Gly Asp Gly Ala Gly Asn Gly Leu Arg Gly
          35                  40                  45            
 Pro Pro Pro Leu Leu Ser Ser Cys Thr Asp Pro Pro Cys Met Gly Thr
      50                  55                  60                
 Pro Cys Val His Gly Pro Ala Arg Val Asp Val Pro Cys Val His Pro
  65                  70                  75                  80
 Ser Phe Arg Asp Pro Pro Leu Asn Gly Pro Pro Asp Val Asp Thr Arg
                  85                  90                  95    
 Ile Arg Pro Pro Cys Val Gly Ser Pro Cys Val Asp Pro Ser Arg
             100                 105                 110    



      <210> 1909
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 1909
 Met Leu Met Leu Val Leu Ala Leu Leu Ser Gly Gln Gln Gly Ala Asp
   1               5                  10                  15    
 Thr Leu Ser Ser Ala Phe Val Lys Asn Gln Tyr Thr Asn Thr Pro Glu
              20                  25                  30        
 Cys Asn Val Thr Lys Arg Pro Pro Asp Gln Glu Ser Lys Ala Ser Ser
          35                  40                  45            
 Gln Glu Asn Glu Gly Ala Leu Ala Gly Leu Pro Ser Leu Gln Pro Ala
      50                  55                  60                
 Asp Leu Arg Ser Ile Gln Gly Ala Asp Thr Gln Ser Pro Pro Gly Leu
  65                  70                  75                  80
 Asp Arg Ala His Thr Glu Leu Glu Arg Ser Gly His Ser Ala Met Phe
                  85                  90                  95    
 Leu Glu His Leu Glu Arg Asp Gly Leu Pro Leu Leu Asp Leu Arg Val
             100                 105                 110        
 Ser Arg Ala Gln Met Thr Gly Ser Met Gly Ser Val Ser Leu Ser Gly
         115                 120                 125            
 Leu Phe Ser Trp Ile Leu Ala Ser
     130                 135    



      <210> 1910
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1910
 Met Ala Cys Lys Ala Tyr Val Thr Trp Ser Met Ala Ala Leu Thr Thr
   1               5                  10                  15    
 Ser Phe Ser Thr Leu Ser Phe Thr Ser Gln Leu Gln Pro Pro Cys Ser
              20                  25                  30        
 Thr Leu Glu Met Ser Thr Leu Thr Pro Val Ser Pro Ala Glu Arg Leu
          35                  40                  45            
 Ser Leu Pro Ala Pro Phe Leu Thr Ala His Gly Ala Glu Ser Val Thr
      50                  55                  60                
 Lys Glu Lys Arg Ala Glu
  65                  70



      <210> 1911
      <211> 118
      <212> PRT
      <213> Homo sapiens


      <400> 1911
 Met Gln Leu Gly Thr Gly Leu Leu Leu Ala Ala Val Leu Ser Leu Gln
   1               5                  10                  15    
 Leu Gly Cys Phe Leu Gly Lys Asp Ala Thr Ser Trp Leu Gln Leu Gln
              20                  25                  30        
 Gly Cys Gln Ala Pro Gln Ala Ala Ala Glu Ala Ile Trp Cys His Gln
          35                  40                  45            
 Cys Thr Gly Phe Gly Gly Cys Ser His Gly Ser Arg Cys Leu Arg Asp
      50                  55                  60                
 Ser Thr His Cys Val Thr Thr Ala Thr Arg Val Leu Ser Asn Thr Glu
  65                  70                  75                  80
 Asp Leu Pro Leu Val Thr Lys Met Cys His Ile Gly Cys Pro Asp Ile
                  85                  90                  95    
 Pro Ser Leu Gly Leu Gly Pro Tyr Val Ser Ile Ala Cys Cys Gln Thr
             100                 105                 110        
 Ser Leu Cys Asn His Asp
         115            



      <210> 1912
      <211> 328
      <212> PRT
      <213> Homo sapiens


      <400> 1912
 Met Arg Glu Thr Arg Arg Thr Arg Ser Arg Ile Asn Ala Leu Val Ser
   1               5                  10                  15    
 Pro Leu Ile Leu Val Leu Leu Phe Leu His Leu Trp Trp Glu Ser Pro
              20                  25                  30        
 Glu Asp Ser Val Pro Glu Asp Thr Glu Asp Leu Gln Pro Phe Thr Arg
          35                  40                  45            
 Val Thr Val His Trp Gly Lys Gly Asn Asp Gln Thr Phe Arg Gly Leu
      50                  55                  60                
 Leu Asp Thr Gly Phe Glu Leu Thr Trp Ile Pro Gly Asp Pro Lys Cys
  65                  70                  75                  80
 His Cys Gly Pro Leu Val Lys Val Gly Phe Tyr Glu Gly Gln Val Ile
                  85                  90                  95    
 Ser Arg Val Leu Ala Gln Val Arg Leu Thr Val Gly Pro Arg Thr His
             100                 105                 110        
 Pro Val Val Ile Ser Pro Val Pro Glu Cys Ile Ile Gly Ile Asp Ile
         115                 120                 125            
 Leu Ser Ser Trp Gln Asn Pro His Ile Gly Ser Leu Thr Gly Arg Pro
     130                 135                 140                
 Ser Leu Met Ala Ser Gly Gly Ile Ser Tyr Glu Gln Leu Thr Glu Glu
 145                 150                 155                 160
 Glu Lys Thr Arg Ala Trp Phe Thr Asp Cys Ser Ala Gln Tyr Ala Gly
                 165                 170                 175    
 Thr Thr Arg Lys Trp Thr Ala Ala Ala Leu Gln Pro Leu Ser Arg Thr
             180                 185                 190        
 Ser Leu Lys Asp Ser Ser Val Arg Lys Ser Ser His Trp Ile Gly Arg
         195                 200                 205            
 Thr Val Glu Trp Ser Phe Glu Val Thr Ile Thr Met Thr Val Leu Cys
     210                 215                 220                
 Arg Ala Gly Gln Lys Ala Val Tyr Ala Leu Asn Gln His Pro Ile Tyr
 225                 230                 235                 240
 Asp Thr Val Ser Pro Ile Ala Arg Ile His Gly Pro Gly Ile Lys Val
                 245                 250                 255    
 Gly Lys Val Glu Val Glu Leu Leu Thr Ile Thr Pro Ser Asp Pro Leu
             260                 265                 270        
 Ala Lys Cys Leu Leu Pro Val Pro Thr Thr Leu Cys Ser Ala Gly Leu
         275                 280                 285            
 Glu Val Leu Asp Pro Glu Gly Glu Ile Leu Pro Pro Gly Asp Asn Asn
     290                 295                 300                
 Asp Ser Ile Lys Leu Lys Val Lys Ile Ala Thr Trp Thr Leu Trp Ile
 305                 310                 315                 320
 Pro Pro Thr Phe Lys Ser Thr Gly
                 325            



      <210> 1913
      <211> 473
      <212> PRT
      <213> Homo sapiens


      <400> 1913
 Met Met Met Thr Val Met Met Thr Met Ala Met Val Ile Ser Phe Gln
   1               5                  10                  15    
 Pro Leu Ala Gly Pro Val Arg Met Asn Met Gln Ala Leu Tyr Gly Leu
              20                  25                  30        
 Val Glu Gln Ser Lys Gly Trp Thr Asp Thr Gln Ser Pro Lys Phe Ser
          35                  40                  45            
 Gly Asn Thr His Val Asn Ile Gly Leu Ser Phe Pro Ile Thr Gly Leu
      50                  55                  60                
 Trp Ile Pro Ser Asn Ser Asp Ser Gln Cys Ser Pro Thr Arg Gln Ser
  65                  70                  75                  80
 Leu Ser Leu Ser Glu Gly Glu Glu Gln Met Asp Arg Leu Gln Gln Val
                  85                  90                  95    
 Glu Leu Val Arg Thr Thr Pro Met Ser His Trp Lys Ala Gly Thr Val
             100                 105                 110        
 Gln Ala Trp Leu Glu Val Val Met Ala Met Pro Met Tyr Val Lys Ala
         115                 120                 125            
 Cys Thr Glu Asn Val Lys Ser Gly Lys Val Leu Leu Ser Leu Ser Asp
     130                 135                 140                
 Glu Asp Leu Gln Leu Gly Leu Gly Val Cys Ser Ser Leu His Arg Arg
 145                 150                 155                 160
 Lys Leu Arg Leu Ala Ile Glu Asp Tyr Arg Asp Ala Glu Ala Gly Arg
                 165                 170                 175    
 Ser Leu Ser Lys Ala Ala Glu Leu Asp His His Trp Val Ala Lys Ala
             180                 185                 190        
 Trp Leu Asn Asp Ile Gly Leu Ser Gln Tyr Ser Gln Ala Phe Gln Asn
         195                 200                 205            
 His Leu Val Asp Gly Arg Met Leu Asn Ser Leu Met Lys Arg Asp Leu
     210                 215                 220                
 Glu Lys His Leu Asn Val Ser Lys Lys Phe His Gln Val Ser Ile Leu
 225                 230                 235                 240
 Leu Gly Ile Glu Leu Leu Tyr Gln Val Asn Phe Ser Arg Glu Ala Leu
                 245                 250                 255    
 Gln Glu Arg Arg Ala Arg Cys Glu Thr Gln Asn Ile Asp Pro Val Val
             260                 265                 270        
 Trp Thr Asn Gln Arg Val Leu Lys Trp Val Arg Asp Ile Asp Leu Lys
         275                 280                 285            
 Glu Tyr Ala Asp Asn Leu Thr Asn Ser Gly Val His Gly Ala Val Leu
     290                 295                 300                
 Val Leu Glu Pro Thr Phe Asn Ala Glu Ala Met Ala Thr Ala Leu Gly
 305                 310                 315                 320
 Ile Pro Ser Gly Lys His Ile Leu Arg Arg His Leu Ala Glu Glu Met
                 325                 330                 335    
 Ser Ala Val Phe His Pro Ala Asn Ser Thr Gly Ile Arg Glu Ala Glu
             340                 345                 350        
 Arg Phe Gly Thr Pro Pro Gly Arg Ala Ser Ser Val Thr Arg Ala Gly
         355                 360                 365            
 Lys Glu Glu Asn Ser Ser Gly Leu Lys Tyr Lys Ala Gly Arg Leu Pro
     370                 375                 380                
 Leu Gly Lys Ile Gly Arg Gly Phe Ser Ser Lys Asp Pro Asp Phe His
 385                 390                 395                 400
 Asp Asp Tyr Gly Ser Leu Gln Asn Glu Asp Cys Gly Asp Asp Asp Pro
                 405                 410                 415    
 Gln Ser Arg Leu Glu Gln Cys Arg Leu Glu Gly Tyr Asn Ser Leu Glu
             420                 425                 430        
 Val Thr Asn Val Val Leu Lys Leu Gln Ser Thr Ala Gln Lys Gly Glu
         435                 440                 445            
 Asp Pro Arg Pro Gly Ser Arg Thr Ser Val Ser Ser Gln Met Gln Leu
     450                 455                 460                
 Val Leu Pro Lys Cys Tyr Thr Trp Thr
 465                 470            



      <210> 1914
      <211> 159
      <212> PRT
      <213> Homo sapiens


      <400> 1914
 Met His Val Val Met Ile Leu Ile Met Lys Cys Leu Ser Leu Asp Phe
   1               5                  10                  15    
 Ser Cys Ile Phe Gln Val Asn Gly Lys Asp Leu Ser Lys Ala Thr His
              20                  25                  30        
 Glu Glu Ala Val Glu Ala Phe Arg Asn Ala Lys Glu Pro Ile Val Val
          35                  40                  45            
 Gln Val Leu Arg Arg Thr Pro Leu Ser Arg Pro Ala Tyr Gly Met Ala
      50                  55                  60                
 Ser Glu Val Gln Leu Met Asn Ala Ser Thr Gln Thr Asp Ile Thr Phe
  65                  70                  75                  80
 Glu His Ile Met Ala Leu Ala Lys Leu Arg Pro Pro Thr Pro Pro Val
                  85                  90                  95    
 Pro Asp Ile Cys Pro Phe Leu Leu Ser Asp Arg Tyr Phe Ser Ile Ile
             100                 105                 110        
 Ser Ser Lys Ala Leu Phe Val Ser Ile Cys His Val Lys Gln Met Leu
         115                 120                 125            
 Lys Arg Ser Ser Ser Thr Ser Arg Leu Thr Val Met Glu Thr Gly Phe
     130                 135                 140                
 Pro Ala Pro Phe Gly Lys Cys Leu Pro Cys Phe Asp Met Cys Asn
 145                 150                 155                



      <210> 1915
      <211> 97
      <212> PRT
      <213> Homo sapiens


      <400> 1915
 Met Gly Gln Phe Leu Thr His Trp Ser Ala Val Thr Ile Leu Met Ser
   1               5                  10                  15    
 Ser Cys Thr Asn Ser Pro Leu Tyr Lys Gly Ala Glu His Thr Ser Tyr
              20                  25                  30        
 Val Ser Glu Asn Lys Val Gln Glu Val Tyr Phe Tyr Leu Arg Gln Tyr
          35                  40                  45            
 Leu Lys Ile Val Cys Tyr Ser Leu Gln Ser Glu Ser Ser Ser Gln Tyr
      50                  55                  60                
 Leu Ser Ser Arg His Met Glu Pro Phe Leu Pro Ser Ile Met Phe Asn
  65                  70                  75                  80
 His Leu Met Asn Glu Val Leu Lys Leu Leu Thr His Ala Pro Tyr Asn
                  85                  90                  95    
 Leu
    



      <210> 1916
      <211> 443
      <212> PRT
      <213> Homo sapiens


      <400> 1916
 Met Lys Ala Met Pro Trp Asn Trp Thr Cys Leu Leu Ser His Leu Leu
   1               5                  10                  15    
 Met Val Gly Met Gly Ser Ser Thr Leu Leu Thr Arg Gln Pro Ala Pro
              20                  25                  30        
 Leu Ser Gln Lys Gln Arg Ser Phe Val Thr Phe Arg Gly Glu Pro Ala
          35                  40                  45            
 Glu Gly Phe Asn His Leu Val Val Asp Glu Arg Thr Gly His Ile Tyr
      50                  55                  60                
 Leu Gly Ala Val Asn Arg Ile Tyr Lys Leu Ser Ser Asp Leu Lys Val
  65                  70                  75                  80
 Leu Val Thr His Glu Thr Gly Pro Asp Glu Asp Asn Pro Lys Cys Tyr
                  85                  90                  95    
 Pro Pro Arg Ile Val Gln Thr Cys Asn Glu Pro Leu Thr Thr Thr Asn
             100                 105                 110        
 Asn Val Asn Lys Met Leu Leu Ile Asp Tyr Lys Glu Asn Arg Leu Ile
         115                 120                 125            
 Ala Cys Gly Ser Leu Tyr Gln Gly Ile Cys Lys Leu Leu Arg Leu Glu
     130                 135                 140                
 Asp Leu Phe Lys Leu Gly Glu Pro Tyr His Lys Lys Glu His Tyr Leu
 145                 150                 155                 160
 Ser Gly Val Asn Glu Ser Gly Ser Val Phe Gly Val Ile Val Ser Tyr
                 165                 170                 175    
 Ser Asn Leu Asp Asp Lys Leu Phe Ile Ala Thr Ala Val Asp Gly Lys
             180                 185                 190        
 Pro Glu Tyr Phe Pro Thr Ile Ser Ser Arg Lys Leu Thr Lys Asn Ser
         195                 200                 205            
 Glu Ala Asp Gly Met Phe Ala Tyr Val Phe His Asp Glu Phe Val Ala
     210                 215                 220                
 Ser Met Ile Lys Ile Pro Ser Asp Thr Phe Thr Ile Ile Pro Asp Phe
 225                 230                 235                 240
 Asp Ile Tyr Tyr Val Tyr Gly Phe Ser Ser Gly Asn Phe Val Tyr Phe
                 245                 250                 255    
 Leu Thr Leu Gln Pro Glu Met Val Ser Pro Pro Gly Ser Thr Thr Lys
             260                 265                 270        
 Glu Gln Val Tyr Thr Ser Lys Leu Val Arg Leu Cys Lys Glu Asp Thr
         275                 280                 285            
 Ala Phe Asn Ser Tyr Val Glu Val Pro Ile Gly Cys Glu Arg Ser Gly
     290                 295                 300                
 Val Glu Tyr Arg Leu Leu Gln Ala Ala Tyr Leu Ser Lys Ala Gly Ala
 305                 310                 315                 320
 Val Leu Gly Arg Thr Leu Gly Val His Pro Asp Asp Asp Leu Leu Phe
                 325                 330                 335    
 Thr Val Phe Ser Lys Gly Gln Lys Arg Lys Met Lys Ser Leu Asp Glu
             340                 345                 350        
 Ser Ala Leu Cys Ile Phe Ile Leu Lys Gln Ile Asn Asp Arg Ile Lys
         355                 360                 365            
 Glu Arg Leu Gln Ser Cys Tyr Arg Gly Glu Gly Thr Leu Asp Leu Ala
     370                 375                 380                
 Trp Leu Lys Val Lys Asp Ile Pro Cys Ser Ser Ala Val Tyr Leu Leu
 385                 390                 395                 400
 Leu Gln Pro Phe Pro Gly Ser Leu His Arg Asp Tyr Gln Ala Leu Leu
                 405                 410                 415    
 Gly Ser Leu Gly Ser Gly Ser Gly Phe Ala Ala Leu Pro Leu Ser Leu
             420                 425                 430        
 Gly Asn Cys Trp Arg Lys Glu Thr Val Cys Ile
         435                 440            



      <210> 1917
      <211> 180
      <212> PRT
      <213> Homo sapiens


      <400> 1917
 Met Leu Leu Tyr Leu Pro Pro Ala Leu Ser Thr Arg Trp Met Leu Gly
   1               5                  10                  15    
 Leu Cys Arg Pro Ala Asn Gln Lys Arg Ala His Glu Ala His Ala Lys
              20                  25                  30        
 Pro Ala Ser Ala Leu Ser Ile Asn Ser Gly Pro Leu Ser Thr Gly Ser
          35                  40                  45            
 Arg Gly Met Leu Lys Ser Pro Met Pro Val Val Glu Phe Tyr Val Ala
      50                  55                  60                
 Gly Ile Gly Thr Ser Val Asp Pro Gly Thr Ala Pro Arg Lys Gly Leu
  65                  70                  75                  80
 Gly Leu Arg His Lys Glu Glu Gly Ala Gly Leu Gln Ala His Arg Pro
                  85                  90                  95    
 Val Trp Gly Ser Glu Gly Phe Ala Gln Ala Val Gln Gly Pro Gly Gly
             100                 105                 110        
 Cys Arg Thr Cys Ser Lys Gln Gln Pro Met Pro Phe Ala Lys Thr Asp
         115                 120                 125            
 Thr Cys Ala Ser Asp Lys His Val Glu Lys Lys Leu Phe His Val Gln
     130                 135                 140                
 Thr Asp Thr Asn Ala Ile Ser Phe Leu Thr Leu Leu Ser Val Glu Gly
 145                 150                 155                 160
 Asp Pro Gly Ile Gln Ile Cys Ile Thr Glu Asp Ile Gln Leu Gly Lys
                 165                 170                 175    
 Thr Pro Pro Pro
             180



      <210> 1918
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1918
 Met Gly Trp Ala Leu Pro Gly Ala Leu Gly Gly Val Leu Gly Leu Glu
   1               5                  10                  15    
 Gly Ile Leu Pro Ala Ile Pro Lys Ser Arg Arg Gly Ser Gln Arg Ser
              20                  25                  30        
 Ala His Asp Pro Lys Val Ser His Ser Thr Ala Ser Gly Ala Asn Ala
          35                  40                  45            
 Cys Tyr Ser Arg Gln Pro Val Pro Arg Ser Trp Lys Val Arg Lys Ser
      50                  55                  60                
 Ala Arg Ser Ser His Ala Glu Asn
  65                  70        



      <210> 1919
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1919
 Met Ala Leu Phe Gln Ala Gly Leu Val Ile Leu Leu Glu Ala Ala Ile
   1               5                  10                  15    
 Leu Leu Ser Leu Val Lys Cys Asn Trp Leu Tyr Leu Ser Asp Val Ala
              20                  25                  30        
 Leu Arg Phe Cys Gln Ser Arg Tyr Tyr Phe Asn Leu Leu Arg Gln Ala
          35                  40                  45            
 Ser Thr Ser Arg Ser Arg Lys Val Ser Lys Val Met Leu Val Leu Lys
      50                  55                  60                
 Ala Leu Glu Ser Ser Asp Leu Thr Glu Val Val Gly Tyr Gly Phe Tyr
  65                  70                  75                  80
 Leu Tyr Lys Cys Gln Thr Lys Trp Met Pro Gln Ser Met Ala Glu Trp
                  85                  90                  95    
 His Cys Gln Cys Gln Glu Arg Gly Met Leu Lys Leu Val Glu Ser Met
             100                 105                 110        
 Asn Ala Val Lys Leu Arg Pro Trp Val Lys
         115                 120        



      <210> 1920
      <211> 193
      <212> PRT
      <213> Homo sapiens


      <400> 1920
 Met Ser Leu Gln Val Ser Glu Ala Leu Ser Arg Glu Glu Ala Leu Glu
   1               5                  10                  15    
 Trp Ile Ala Ser Leu Phe Cys Trp Leu Leu Gly His Leu Leu Leu Ser
              20                  25                  30        
 Ala Glu Arg Val Ala Leu Leu Cys Ser Trp Ser Ser Ile Ile Cys Ser
          35                  40                  45            
 Ala Leu Ala Glu Pro Gly Ala Phe Ile Gly Leu Leu Glu Gly Lys Cys
      50                  55                  60                
 Met Leu Ile Ser Pro Trp Ala Ala Met Gly Arg Ser Arg Lys Asn His
  65                  70                  75                  80
 His Glu Phe Ala Leu Gln Ile Ser Thr Ala Ser Pro Val Pro Arg Leu
                  85                  90                  95    
 Gln Ala Phe Ser Gln Gly Ser Ala Leu Phe Cys Pro Lys Cys Arg Asp
             100                 105                 110        
 Thr Trp Val Cys Ser Arg Asn Met Gly Cys Ser Leu Asp Pro Arg Glu
         115                 120                 125            
 Val Glu Leu Leu Val Pro Gln Lys Ile Gln Val Asn Asp Gln Ile Val
     130                 135                 140                
 Glu Val Asp Gly Ile Ser Leu Val Gly Val Thr Gln Asn Phe Ala Ala
 145                 150                 155                 160
 Thr Val Leu Arg Asn Thr Lys Gly Asn Val Arg Gln Tyr Gly His Leu
                 165                 170                 175    
 Tyr Thr Asp Asp His Glu Glu Asn Pro Lys Val Ser Thr Lys Asp Ala
             180                 185                 190        
 Thr
    



      <210> 1921
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 1921
 Met Gly Ser Cys His Ser Ser Gln Thr Leu Leu Pro Phe Pro Phe Trp
   1               5                  10                  15    
 Ala Leu Ser Ala Ala Pro Cys Glu Arg Met Cys Trp Arg Ser Pro Gln
              20                  25                  30        
 Tyr Pro Ser Ser Gly Lys Ser Ala Leu Ser Arg Pro Phe Leu Arg Ala
          35                  40                  45            
 Gly Ser Arg Asn Ser Lys Thr Lys Gln Ala Glu Leu Asp Ser Gly Ala
      50                  55                  60                
 Ala Leu Lys Gly Leu Glu Gly Tyr Met Ser Ala Val Leu Glu Lys Asn
  65                  70                  75                  80
 Ser Ser Arg Leu Val Ala Leu Leu Ser Phe Ser Cys Ser His Pro Ser
                  85                  90                  95    
 Phe Arg Arg Lys Cys Pro Trp Phe Leu Gly Pro Gly Ser Ala Ala Gln
             100                 105                 110        
 Leu Cys Cys Gln Thr Ser Ala Gly Val Val Asp Cys Thr Gly Tyr Thr
         115                 120                 125            
 Ala Val Pro Ala Thr Thr Leu Arg Pro Leu Ser Ala Gly Ile Asp Pro
     130                 135                 140                
 Pro Met Phe Ser
 145            



      <210> 1922
      <211> 40
      <212> PRT
      <213> Homo sapiens


      <400> 1922
 Met Trp Asp Ser Leu Lys Leu Leu Val Ala Leu Val Leu Asp Ile Leu
   1               5                  10                  15    
 Ser Ser Glu Lys Gly Ser Ala Asp Glu Ser Leu Glu Ser Phe Ser Gly
              20                  25                  30        
 Gln Ser His Phe Arg Asn Gly Asn
          35                  40



      <210> 1923
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 1923
 Met Leu Gln Val Leu Asp Leu Leu Phe Phe Val Thr Met Thr Glu Asn
   1               5                  10                  15    
 Ser Tyr Ile Val Phe Glu Ala Ser Asn Glu Leu Asn Thr Phe Asn Ile
              20                  25                  30        
 Ile Met Met Ile Pro Asn Glu Leu Ile Ile Asn Tyr Gly Gln Thr Pro
          35                  40                  45            
 Leu Cys Arg Asn Thr Leu Ser Asp Asn His Asp Met Ser Gly Ile Glu
      50                  55                  60                
 Gly Leu Ser Phe Pro Leu Ser His Tyr Ala Glu Gln Pro Leu Val Thr
  65                  70                  75                  80
 Asn Tyr Ser Lys Ile Asn Ile Pro Tyr Leu Leu Gln Leu Val Ser Arg
                  85                  90                  95    
 Ala Leu Ala Glu Ser Pro Gln Ser Gln Arg Asn Asp
             100                 105            



      <210> 1924
      <211> 104
      <212> PRT
      <213> Homo sapiens


      <400> 1924
 Met Asn Tyr Leu Leu Trp Pro Met Val Leu Thr Arg Ile Thr Cys Thr
   1               5                  10                  15    
 Asn Thr Met Ser Phe Pro Leu Asn Pro Cys Leu Thr Arg Arg Ser Ala
              20                  25                  30        
 Arg Phe Asn Ser Pro Cys Ser Ala Ala Pro Gly Asn Ser Ser Ser Ser
          35                  40                  45            
 Ser Ser Lys Val Gln His Pro Pro Asp Ser His Lys Pro Leu Thr Val
      50                  55                  60                
 Trp Thr Gln Pro Gln Thr Leu Pro Leu Ala Asp Val Lys Val Pro Val
  65                  70                  75                  80
 Thr Trp Pro Asp Glu Ser Gln Glu Ile Ile Gly Cys Arg Ser Asn His
                  85                  90                  95    
 Arg Pro Ala Leu Lys Leu Phe Gln
             100                



      <210> 1925
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 1925
 Met Lys Thr Ser Arg Arg Gly Arg Ala Leu Leu Ala Val Ala Leu Asn
   1               5                  10                  15    
 Leu Leu Ala Leu Leu Phe Ala Thr Thr Ala Phe Leu Thr Thr His Trp
              20                  25                  30        
 Cys Gln Gly Thr Gln Arg Val Pro Lys Pro Gly Cys Gly Gln Gly Gly
          35                  40                  45            
 Arg Ala Asn Cys Pro Asn Ser Gly Ala Asn Ala Thr Ala Asn Gly Thr
      50                  55                  60                
 Ala Ala Pro Ala Ala Ala Ala Ala Ala Ala Thr Ala Ser Gly Asn Gly
  65                  70                  75                  80
 Pro Pro Gly Gly Ala Leu Tyr Ser Trp Glu Thr Gly Asp Asp Arg Phe
                  85                  90                  95    
 Leu Phe Arg Asn Phe His Thr Gly Ile Trp Tyr Ser Cys Glu Glu Glu
             100                 105                 110        
 Leu Ser Gly Leu Asp Pro Gln Thr Arg Glu Pro Ser Thr Pro Ile Ala
         115                 120                 125            
 Asn Pro Arg Arg Thr Ser Gln Thr Gly Glu Leu Phe His Lys Thr Thr
     130                 135                 140                
 Pro Tyr Lys Ser Leu Leu Lys Cys Pro Pro Val Cys Glu Ala Phe Leu
 145                 150                 155                 160
 Asp His Pro Thr Glu Ile Ser Arg Leu Ala Ala Arg Arg His Ser Pro
                 165                 170                 175    
 Ala Pro Leu Met Ser Pro Leu Leu
             180                



      <210> 1926
      <211> 170
      <212> PRT
      <213> Homo sapiens


      <400> 1926
 Met Gly Lys Ala Ala Ala Ala Val Ala Phe Gly Ala Glu Val Gly Val
   1               5                  10                  15    
 Arg Leu Ala Leu Phe Ala Ala Phe Leu Val Thr Glu Leu Leu Pro Pro
              20                  25                  30        
 Phe Gln Arg Leu Ile Gln Pro Glu Glu Met Trp Leu Tyr Arg Asn Pro
          35                  40                  45            
 Tyr Val Glu Ala Glu Tyr Phe Pro Thr Lys Pro Met Pro Arg Pro Asp
      50                  55                  60                
 Phe Phe Tyr Arg Cys Phe Pro Asp Gly Leu Ala His Ser Asp Leu Met
  65                  70                  75                  80
 Cys Thr Gly Asp Lys Asp Val Val Asn Glu Gly Arg Lys Ser Phe Pro
                  85                  90                  95    
 Ser Gly His Ser Ser Ser Val Ile Ala Leu Ser Arg Thr Cys Asp Tyr
             100                 105                 110        
 Lys His His Trp Gln Asp Val Leu Val Gly Ser Met Ile Gly Met Thr
         115                 120                 125            
 Phe Ala Tyr Val Cys Tyr Arg Gln Tyr Tyr Pro Pro Leu Thr Asp Ala
     130                 135                 140                
 Glu Cys His Lys Pro Phe Gln Asp Lys Leu Val Leu Ser Thr Ala Gln
 145                 150                 155                 160
 Lys Pro Gly Asp Ser Tyr Cys Phe Asp Ile
                 165                 170



      <210> 1927
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 1927
 Met Ser Lys Arg Gly Leu Met Pro Ile Trp Ala Leu Gly Val His Leu
   1               5                  10                  15    
 Gln His Gly Cys Pro Leu Val Leu Tyr Ile His Gln Gly Pro Asn Val
              20                  25                  30        
 His Leu Arg Pro Gly Val His Leu Gly Ser Asp Val Gln Leu Lys Thr
          35                  40                  45            
 Gly Cys Pro Pro Gly Ala Glu Glu Ser Thr Gln Gly Leu Val Leu Asn
      50                  55                  60                
 Trp Gly Leu Met Thr Thr Arg Gly Gln Gly Leu Val Phe Ile Phe Asp
  65                  70                  75                  80
 Leu Val Tyr Thr Trp Asp Thr Tyr Gly Leu Gly Val Gln Leu Arg Cys
                  85                  90                  95    
 His Asp His Leu Gly Thr Glu Cys Gln Ser Gly Val
             100                 105            



      <210> 1928
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 1928
 Met Ala Val Cys Cys Gly Phe Phe Leu Pro Gln Tyr Ile Gln Pro Leu
   1               5                  10                  15    
 Thr Leu Val Ser Tyr Thr Pro Asp Leu Leu Leu Ser Val Arg Gly Glu
              20                  25                  30        
 Arg Lys Asn Glu Thr Asp Ser Ser Leu Asn Gln Glu Ala Pro Thr Glu
          35                  40                  45            
 Glu Ala Ser Ser Val Phe Pro Lys Leu Thr Ser Ala Lys Pro Phe Ser
      50                  55                  60                
 Ser Leu Pro Asp Leu Arg Asn Ile Asn Leu Ser Ser Ser Lys Leu Glu
  65                  70                  75                  80
 Pro Ser Lys Pro Asn Phe Ser Ile Lys Glu Ala Lys Ser Ala Ser Ala
                  85                  90                  95    
 Val Asn Val Phe Thr Gly Thr Val Ile Cys Ser Ser Thr Pro Leu Val
             100                 105                 110        
 Ser Ala Met Pro Leu Met Ser Gly Ile Thr Cys Ser Ser Asn Pro Ala
         115                 120                 125            
 Leu Cys
     130



      <210> 1929
      <211> 273
      <212> PRT
      <213> Homo sapiens


      <400> 1929
 Met Asn Leu Ser Phe Leu Leu Cys Trp Leu Met Gly Leu Gly Ala Phe
   1               5                  10                  15    
 Gln Glu Leu Val Ile Pro Arg Gly Pro Lys Glu Ile Ile Leu Asn Lys
              20                  25                  30        
 Ala Leu Cys Lys Asp Trp Val Ser Pro Asp Gln Gly Ser Asn Trp Leu
          35                  40                  45            
 Ala Phe Tyr Leu Gln Ile Gln Pro Gln Ile Ser Pro Ser Lys Leu Leu
      50                  55                  60                
 Lys Ala Thr Leu Thr Ala Asn Gly Ser Ser Glu Phe Asn Gly Ile Val
  65                  70                  75                  80
 Met Ser Pro Gly Gly Ser Ile Pro Pro Ser Arg Thr Lys Thr Phe Arg
                  85                  90                  95    
 Pro Ala Glu Arg Asn Val Glu Gly Thr Gly Ser Lys Asn Phe Ala Asn
             100                 105                 110        
 Glu Ser Leu Gly Val Leu Phe Pro Pro Lys Pro Ser Asn Arg Pro Arg
         115                 120                 125            
 Ala Val Ser Glu Lys Lys Ser Asn Tyr Leu Leu Lys Met Ala Gly Pro
     130                 135                 140                
 Tyr Ser Lys Ile Leu Glu Ala Ser Ala Val Ile His Gln Trp Gly Pro
 145                 150                 155                 160
 Thr Arg Gly Ser Lys Gln Tyr Pro Tyr Leu Pro Leu Thr Pro Gln Ala
                 165                 170                 175    
 Pro Leu Asp Leu Leu Gly His Met Ala Gln Val Val Glu Gln Leu Ala
             180                 185                 190        
 Gln Gln Pro Gly Pro Val Ala Glu Pro Ser Pro Val Val Asp Pro Ile
         195                 200                 205            
 Gln Asn Trp Gln Pro Phe Arg Ser Leu Asn Lys Trp Ala Arg Val Thr
     210                 215                 220                
 His Pro Asn Glu Glu Cys Ala Ala Phe Lys Ile Gln Ile Gly Pro Leu
 225                 230                 235                 240
 Gly Phe Val Pro Leu Ser Trp Phe Gly Arg Asp Leu Met Gln Gln Val
                 245                 250                 255    
 Ile Leu His Leu Arg Lys Asn Ile Ser Thr Gly Pro Thr Pro Leu Asp
             260                 265                 270        
 Pro
    



      <210> 1930
      <211> 260
      <212> PRT
      <213> Homo sapiens


      <400> 1930
 Met Ala Gly Pro Pro Arg Leu Leu Leu Leu Pro Leu Leu Leu Ala Leu
   1               5                  10                  15    
 Ala Arg Gly Leu Pro Gly Ala Leu Ala Ala Gln Glu Val Gln Gln Ser
              20                  25                  30        
 Pro His Cys Thr Thr Val Pro Val Gly Ala Ser Val Asn Ile Thr Cys
          35                  40                  45            
 Ser Thr Ser Gly Gly Leu Arg Gly Ile Tyr Leu Arg Gln Leu Gly Pro
      50                  55                  60                
 Gln Pro Gln Asp Ile Ile Tyr Tyr Glu Asp Gly Val Val Pro Thr Thr
  65                  70                  75                  80
 Asp Arg Arg Phe Arg Gly Arg Ile Asp Phe Ser Gly Ser Gln Asp Asn
                  85                  90                  95    
 Leu Thr Ile Thr Met His Arg Leu Gln Leu Ser Asp Thr Gly Thr Tyr
             100                 105                 110        
 Thr Cys Gln Ala Ile Thr Glu Val Asn Val Tyr Gly Ser Gly Thr Leu
         115                 120                 125            
 Val Leu Val Thr Gly Thr Val Pro Arg Met Ala Gln Met Leu Gly Arg
     130                 135                 140                
 Pro Thr Lys Ala Ser Ala Leu Pro Ala Pro Ser Gly Leu Pro Pro Ser
 145                 150                 155                 160
 Leu Thr Arg Arg Gln Pro Leu Pro Ser Leu Thr Arg Gln Gln Pro Leu
                 165                 170                 175    
 Pro Ser Leu Arg Ala Trp Arg Leu Trp Asn Ser Gln Gly Gly Ser Gly
             180                 185                 190        
 Leu Gly Gly Glu Gly Gly Gly Pro Ala Pro Lys Arg Pro Glu Gly Glu
         195                 200                 205            
 Gly Ala Ala Gln Ala Leu Gly Arg Ala Val Arg Val Arg Val Leu Gln
     210                 215                 220                
 Ile Lys Lys Leu Cys Ser Trp Arg Asp Lys Asn Ser Ala Ala Cys Val
 225                 230                 235                 240
 Val Tyr Glu Asp Met Ser His Ser Arg Cys Asn Thr Leu Ser Ser Pro
                 245                 250                 255    
 Asn Gln Tyr Gln
             260



      <210> 1931
      <211> 203
      <212> PRT
      <213> Homo sapiens


      <400> 1931
 Met Phe Gly Arg Gly Ile Thr Gln Lys Arg Cys Arg Phe Leu Leu Ala
   1               5                  10                  15    
 Val Phe Ile Lys Leu Gly Ala Ala Gly Ser Cys Gly Glu Gly Gly Glu
              20                  25                  30        
 Cys Thr Ala Ser Val Gln Lys Ala Asp Lys Asn Leu Glu Ile Val Arg
          35                  40                  45            
 Arg Tyr Thr Leu Ala Asp Trp Tyr Pro Phe Thr Phe Thr Val Gln Gly
      50                  55                  60                
 Gly Thr Ile Ile Ser Lys Ile Val Gly Lys Met Ala Val Trp Gly Tyr
  65                  70                  75                  80
 Ile Val His Ile Leu Val Ile His Gly Ile Phe Thr Gln Leu Ser Leu
                  85                  90                  95    
 Met Ala Leu Arg Lys Pro Leu Arg Arg Thr Lys Cys Gly Val Asn Gly
             100                 105                 110        
 Glu His Val Ala Gln Gln Leu Pro Glu Gly Thr Phe Ser Lys Leu Lys
         115                 120                 125            
 Val Arg Gly His Trp Ala Glu Thr Ala Lys Leu Trp Asn Ile Asn Gly
     130                 135                 140                
 Asp Val Val Gly Lys Glu Ser Ile Gln Thr Ile Arg Val Val Met Arg
 145                 150                 155                 160
 His Tyr Pro Ala Gln Phe Asn Val Ser Lys Asp Tyr Tyr Met Leu Leu
                 165                 170                 175    
 Ser Gly Met Leu Pro Leu Lys Gly Gly Arg Phe Ser Trp Gln Met Pro
             180                 185                 190        
 Phe Asp Ser Val Ile Ile Leu Phe Leu Ser Thr
         195                 200            



      <210> 1932
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 1932
 Met Leu Cys Val Leu Arg Gln Val Pro Leu Gln Gly Leu Ser Leu Pro
   1               5                  10                  15    
 Phe Leu Phe Pro Thr Asp Trp Asn Asn Cys Leu Leu Leu His Gly Arg
              20                  25                  30        
 Asn Thr Ser Arg Thr Cys Leu Thr Ala Pro His Glu Ser Ile Thr Ile
          35                  40                  45            
 Asn Leu Thr Ser His Arg Ser Met Ser Ile Phe Arg Ala Gln Met Lys
      50                  55                  60                
 Pro Trp Ala Pro Val Ile Arg Ser Cys His Cys Trp Leu Ser Ala Glu
  65                  70                  75                  80
 Pro His Thr Ser Val Val Arg Lys Pro Thr Pro His Ser Lys Pro Ser
                  85                  90                  95    
 Thr Ala Pro Thr Val Met Leu Thr Arg Lys Arg Ser Glu Asn Pro Leu
             100                 105                 110        
 Gln Ser Arg Tyr Cys Gly Gly Gly Arg Thr Leu Val Ala Ala Asn Pro
         115                 120                 125            
 Thr Pro Ser Phe Tyr Ser Arg Gly Lys Arg Ser Ser Glu Arg Leu Ser
     130                 135                 140                
 His Leu Val Lys Val Thr Gln Gln Phe Leu Gly Gly Lys Val Arg Thr
 145                 150                 155                 160
 Ser Arg Ser Pro Lys Ser His Pro Arg Ala Leu Ala Thr
                 165                 170            



      <210> 1933
      <211> 40
      <212> PRT
      <213> Homo sapiens


      <400> 1933
 Met Ser Thr Val Val Val Cys Ile Val Leu Cys Phe Val Glu Phe Trp
   1               5                  10                  15    
 Gly Phe Leu Ala Gly Gln Val Cys Leu Val Thr His Lys Tyr Ser Asp
              20                  25                  30        
 Asn Val Gly Ala Gly Leu Pro Leu
          35                  40



      <210> 1934
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 1934
 Met Gly Tyr Pro His Ala Ala Thr Leu Val Ile Met Thr Cys Pro Leu
   1               5                  10                  15    
 Leu Arg Ser Leu Arg Leu Thr Ala Gln Asn Leu Thr Pro Pro Arg Gly
              20                  25                  30        
 Pro Ala Val Pro His Trp Cys Arg Pro Ala Glu Ser Gly Pro Val Ser
          35                  40                  45            
 Arg Ala Ser Gly Val Arg Thr Ala Ile Glu Gly Ser Pro Leu Pro Arg
      50                  55                  60                
 Gln Pro Arg Ala Pro Asn Val Glu Ala Ala Gly Cys Gly Val Gln Glu
  65                  70                  75                  80
 Cys Pro Leu Thr Ser Leu Leu Leu Gly Arg Asp Leu Ser Pro Asp Leu
                  85                  90                  95    
 Ala Thr Gly His Asn Pro Ala Ser Gly Met Thr Ser Cys Arg His Leu
             100                 105                 110        
 Gln Ile Gln Trp Leu Glu Val Ala Ala Gln
         115                 120        



      <210> 1935
      <211> 182
      <212> PRT
      <213> Homo sapiens


      <400> 1935
 Met Pro Gln Val Arg Lys Leu Lys Tyr Leu Leu Val Trp Val Asp Thr
   1               5                  10                  15    
 Phe Thr Gly Trp Leu Glu Ala Phe Pro Thr Gly Ser Glu Lys Ala Thr
              20                  25                  30        
 Thr Ile Ile Ser Ser Val Leu Ser Asp Ile Ile Pro Trp Phe Gly Leu
          35                  40                  45            
 Pro Thr Ser Ile Gln Ser Asn Asn Arg Leu Ala Phe Thr Ser Gln Ile
      50                  55                  60                
 Thr Gln Ala Ile Ser Gln Ala Leu Gly Ile Gln Trp Asn Leu His Thr
  65                  70                  75                  80
 Pro Tyr Arg Pro Gln Ser Ser Gly Lys Val Lys Gln Thr Asn Gly Leu
                  85                  90                  95    
 Leu Lys Val His Leu Thr Lys Leu Ser Leu Gln Leu Lys Lys Asp Trp
             100                 105                 110        
 Thr Val Leu Leu Pro Leu Ala Leu Leu Arg Ile Arg Ala Cys Pro Arg
         115                 120                 125            
 Ile Ala Thr Gly Pro Ser Phe Leu Val Glu Ser Ala Phe Thr Arg Lys
     130                 135                 140                
 Ala Gln Leu Lys Leu Thr His His Gly Asp Tyr Gly Tyr Glu Leu Pro
 145                 150                 155                 160
 Val Thr Ala Phe Val Arg Arg Glu His Cys Asn Arg Glu Arg His Gly
                 165                 170                 175    
 Val Val Ala Glu Gln Met
             180        



      <210> 1936
      <211> 182
      <212> PRT
      <213> Homo sapiens


      <400> 1936
 Met Lys Ser Gly Leu Leu Phe Ile Leu Arg Val Leu Leu Tyr Leu Pro
   1               5                  10                  15    
 Tyr Ser Phe Ser Leu Glu Glu Ala Ser Gln Ser Ile Ser Ser Asp Asn
              20                  25                  30        
 Gln Leu Pro Pro Gln Thr Asp Thr Thr Cys His Ser Val Pro Gly Pro
          35                  40                  45            
 Cys Cys Gly Ser Ala Phe Gly Gln Cys Arg Ala Leu Trp Pro Val Ala
      50                  55                  60                
 Leu Gln His Leu Gly Gln Leu Leu Leu Ala Ser Gly Gly Pro Cys Leu
  65                  70                  75                  80
 Pro Ala Gln Gly Thr His Asn Ile Gly Ala Glu Pro Gly Lys Pro Phe
                  85                  90                  95    
 Leu Asp Gln Ile Pro Ser Arg Lys Gln Ser Thr Met Ala Ser Glu Ser
             100                 105                 110        
 Asn Ser Lys Glu Arg Pro Thr Asp Arg Ala Arg Leu Leu His Tyr Leu
         115                 120                 125            
 Asp Lys Gly Arg Ile Ile Asp Cys Glu Val Ser Leu His Met Asp Arg
     130                 135                 140                
 Leu Pro Leu Glu Arg Arg Val Glu Thr Glu Thr Asp Pro Ser Gly Gln
 145                 150                 155                 160
 Asn Pro Lys Cys Lys Gln Glu Leu Cys Pro Glu Arg Gly Gly Gly Gly
                 165                 170                 175    
 Arg Ser Met Lys Ala Ala
             180        



      <210> 1937
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 1937
 Met His Leu Pro Ala Gln Pro Gly Ala Leu Arg Ala Pro Leu Leu Leu
   1               5                  10                  15    
 Thr Leu Ala Ala Leu Val His Val Gly Val Gln Ser Arg Gly Ser Arg
              20                  25                  30        
 Ser Arg Phe Leu Gly Cys Leu Glu Pro Ile Glu Arg Ser Phe Leu Gly
          35                  40                  45            
 Glu Ala Ile Ala Ser Val Leu Pro Gln Gly Thr Tyr Phe Gly Arg Ser
      50                  55                  60                
 Ser Lys Gln Glu Met Ala Leu Asn Leu Gly Ser Ala Thr Asn Trp Cys
  65                  70                  75                  80
 Asn Thr Ser Asp Asp Asp Trp Gly Asp His Cys Arg Pro Tyr Glu Val
                  85                  90                  95    
 Pro Gln Thr Gly Ala Thr Arg Arg Met Met Thr Gly Val Thr Thr Ala
             100                 105                 110        
 Asp Leu Met Lys Cys His Leu Pro Leu Thr Ile Pro His Met Lys Asn
         115                 120                 125            
 Tyr Leu Lys Ile Lys Thr
     130                



      <210> 1938
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 1938
 Met Trp Gln Cys Leu Phe Leu Leu Val Leu Gln Pro Ser Arg Arg Ser
   1               5                  10                  15    
 Ser Cys Cys Arg Met Leu Ser Tyr Cys Ser Ile Ala Thr Thr Asn Cys
              20                  25                  30        
 Ser Glu Gln Ala Glu Asp Cys Gly Leu Phe Gln Ser Ser Lys Leu Gly
          35                  40                  45            
 Thr Glu Leu Leu Leu His Ser Thr Gln Lys Ser Leu Lys
      50                  55                  60    



      <210> 1939
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 1939
 Met Val Cys Ile Pro Cys Ile Val Ile Pro Val Leu Leu Trp Ile Tyr
   1               5                  10                  15    
 Lys Lys Phe Leu Glu Pro Tyr Ile Tyr Pro Leu Val Ser Pro Phe Val
              20                  25                  30        
 Ser Arg Ile Trp Pro Lys Lys Ala Ile Gln Glu Ser Asn Asp Thr Asn
          35                  40                  45            
 Lys Gly Lys Val Asn Phe Lys Val Pro Ile Gln Phe Leu Leu Arg Gly
      50                  55                  60                
 Ile Leu Gln Ser Pro Ala Leu Glu Ala Gly Lys Leu Thr Val Glu Leu
  65                  70                  75                  80





      <210> 1940
      <211> 311
      <212> PRT
      <213> Homo sapiens


      <400> 1940
 Met Lys Leu Phe Gln Phe Leu Lys Leu Thr Asn Trp Ile Leu Pro Lys
   1               5                  10                  15    
 Ile Thr Lys Phe Lys Pro Ile Lys Ser Ala Glu Asn Val Phe Thr Glu
              20                  25                  30        
 Gly Ser Ser Asn Gly Lys Ala Ser Tyr Phe Gly Ser Lys Cys Lys Val
          35                  40                  45            
 Phe Gln Thr Leu Tyr Thr Ser Ala Gln Lys Ala Glu Leu Val Ala Val
      50                  55                  60                
 Ile Glu Val Leu Thr Ala Phe Asp Met Pro Ile Asn Val Ile Ser Asp
  65                  70                  75                  80
 Ser Ser Tyr Val Val His Ser Thr Gln Leu Ile Glu Asn Ala Gln Leu
                  85                  90                  95    
 Arg Phe His Thr Glu Glu Lys Leu Met Thr Leu Phe Thr Gln Leu Gln
             100                 105                 110        
 Thr Ala Val Arg Ser Arg Met His Arg Phe Tyr Ile Thr His Ile Arg
         115                 120                 125            
 Ala His Thr His Leu Pro Gly Ser Leu Thr Glu Gly Asn Gln Met Ala
     130                 135                 140                
 Asp Arg Leu Val Ala Thr Ala Val Ser Asn Ala Arg His Phe His Ser
 145                 150                 155                 160
 Leu Thr His Val Asn Ala Ser Gly Leu Lys His Arg Tyr Ser Ile Thr
                 165                 170                 175    
 Trp Lys Glu Ala Lys Ala Ile Ile Gln Arg Cys Pro Thr Cys Gln Val
             180                 185                 190        
 Glu Glu Leu Ile Leu Glu Asp Trp Asn Leu Thr Leu Leu Ala Asn Gly
         195                 200                 205            
 Cys His Thr Cys Ser Leu Val Trp Glu Thr Ser Leu Cys Thr Cys Gln
     210                 215                 220                
 Asn Gln Gln Leu Ile Trp Ile Pro Ser Arg His Leu Lys Pro Tyr His
 225                 230                 235                 240
 Glu Pro Asp Pro Lys Glu Glu Ile Pro Gly Gly Ser Arg Gly Pro Pro
                 245                 250                 255    
 Pro Pro Pro Arg His Cys Gly His Val Glu Ala Asp Ala Lys Glu Asp
             260                 265                 270        
 Pro Asn Cys His Glu Gln His Leu Ser Ser Thr Ala Thr His Leu Gly
         275                 280                 285            
 Ala Asp Gln Glu Ala Val Thr Asp Gly Gly Arg Lys Pro Glu Glu Ser
     290                 295                 300                
 Arg Thr Thr Ser Asn Asn Glu
 305                 310    



      <210> 1941
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 1941
 Met Thr Gly Leu Ser Leu Leu Leu Leu Pro Leu Leu Leu Val Gln Ala
   1               5                  10                  15    
 Gly Val Trp Gly Phe Pro Arg Pro Pro Gly Arg Pro Gln Leu Ser Leu
              20                  25                  30        
 Gln Glu Leu Arg Arg Glu Phe Thr Val Ser Leu His Leu Ala Arg Lys
          35                  40                  45            
 Leu Leu Ser Glu Val Arg Gly Gln Ala His Arg Phe Asp Pro Glu Arg
      50                  55                  60                
 Leu Cys Phe Ile Ser Thr Thr Leu Gln Pro Phe His Ala Leu Leu Gly
  65                  70                  75                  80
 Gly Leu Gly Thr Gln Gly Arg Trp Thr Asn Met Glu Arg Met Gln Leu
                  85                  90                  95    
 Trp Ala Met Arg Leu Asp Leu Arg Asp Leu Gln Arg His Leu Arg Phe
             100                 105                 110        
 Gln Val Glu Pro Gly His Pro Pro Pro Pro Gln Thr Thr Trp Glu Arg
         115                 120                 125            
 Arg Leu Ala Gly Ser Phe Ser Asp Pro Met Leu
     130                 135                



      <210> 1942
      <211> 318
      <212> PRT
      <213> Homo sapiens


      <400> 1942
 Met His Lys Glu Leu Pro Lys Val Asn Arg Ala Ile Pro Ile Leu Leu
   1               5                  10                  15    
 Ile Pro Tyr Phe Leu Leu Phe Ser Lys Phe Trp Pro Leu Ala Val Leu
              20                  25                  30        
 Ser Leu Ala Trp Leu Thr Tyr Asp Trp Asn Thr His Ser Gln Gly Gly
          35                  40                  45            
 Arg Arg Ser Ala Trp Val Arg Asn Trp Thr Leu Trp Lys Tyr Phe Arg
      50                  55                  60                
 Asn Tyr Phe Pro Val Lys Leu Val Lys Thr His Asp Leu Ser Pro Lys
  65                  70                  75                  80
 His Asn Tyr Ile Ile Ala Asn His Pro His Gly Ile Leu Ser Phe Gly
                  85                  90                  95    
 Val Phe Ile Asn Phe Ala Thr Glu Ala Thr Gly Ile Ala Arg Ile Phe
             100                 105                 110        
 Pro Ser Ile Thr Pro Phe Val Gly Thr Leu Glu Arg Ile Phe Trp Ile
         115                 120                 125            
 Pro Ile Val Arg Glu Tyr Val Met Ser Met Gly Val Cys Pro Val Ser
     130                 135                 140                
 Ser Ser Ala Leu Lys Tyr Leu Leu Thr Gln Lys Gly Ser Gly Asn Ala
 145                 150                 155                 160
 Val Val Ile Val Val Gly Gly Ala Ala Glu Ala Leu Leu Cys Arg Pro
                 165                 170                 175    
 Gly Ala Ser Thr Leu Phe Leu Lys Gln Arg Lys Gly Phe Val Lys Met
             180                 185                 190        
 Ala Leu Gln Thr Gly Ala Tyr Leu Val Pro Ser Tyr Ser Phe Gly Glu
         195                 200                 205            
 Asn Glu Val Phe Asn Gln Glu Thr Phe Pro Glu Gly Thr Trp Leu Arg
     210                 215                 220                
 Leu Phe Gln Lys Thr Phe Gln Asp Thr Phe Lys Lys Ile Leu Gly Leu
 225                 230                 235                 240
 Asn Phe Cys Thr Phe His Gly Arg Gly Phe Thr Arg Gly Ser Trp Gly
                 245                 250                 255    
 Phe Leu Pro Phe Asn Arg Pro Ile Thr Thr Val Val Gly Glu Pro Leu
             260                 265                 270        
 Pro Ile Pro Arg Ile Lys Arg Pro Asn Gln Lys Thr Val Asp Lys Tyr
         275                 280                 285            
 His Ala Leu Tyr Ile Ser Ala Leu Arg Lys Leu Phe Asp Gln His Lys
     290                 295                 300                
 Val Glu Tyr Gly Leu Pro Glu Thr Gln Glu Leu Thr Ile Thr
 305                 310                 315            



      <210> 1943
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 1943
 Met Leu Lys Val Leu Ser Ala Tyr Trp Val Trp Pro His Pro Val Leu
   1               5                  10                  15    
 Arg His Arg Asn Gln Ser Gly Lys Phe Met Val Gly Val Gly Gly Lys
              20                  25                  30        
 Gln Ser Pro Ala Thr Asp Asn Gly Gly Asp Lys Ala Asp Ser Ser Ser
          35                  40                  45            
 Ser Glu His Pro Lys Ala Leu Gly Lys Gly Gln His Gly Ile Met Val
      50                  55                  60                
 Thr Ser Val Ile Pro Thr Gly Trp Arg Gln Asp Leu Val Gly Glu Glu
  65                  70                  75                  80
 Ala Ser Arg Ile Trp Gly Gln Lys Gly Met
                  85                  90



      <210> 1944
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1944
 Met Lys Trp Leu Leu Ile Tyr Leu Leu Ser Phe Ser Ile Pro Lys Leu
   1               5                  10                  15    
 His Ala Leu Asp Lys Ser Ser Ser Lys Tyr Phe Val Glu Ser Glu Lys
              20                  25                  30        
 Gly Ser Cys Ile Thr Leu Gln Ser Thr Glu Leu Thr Asn His Cys Val
          35                  40                  45            
 Ile Lys Glu Glu Gly Ile Met Gly Asn Ser Leu Trp Phe Thr Leu
      50                  55                  60            



      <210> 1945
      <211> 73
      <212> PRT
      <213> Homo sapiens


      <400> 1945
 Met Lys Ile Leu Phe Val Glu Pro Ala Ile Phe Leu Ser Ala Phe Ala
   1               5                  10                  15    
 Met Thr Leu Thr Gly Pro Leu Thr Thr Gln Tyr Val Tyr Arg Arg Ile
              20                  25                  30        
 Trp Glu Glu Thr Gly Asn Tyr Thr Phe Ser Ser Asp Ser Asn Ile Ser
          35                  40                  45            
 Glu Cys Glu Lys Asn Lys Ser Ser Pro Ile Phe Ala Phe Gln Glu Gly
      50                  55                  60                
 Gly His Gln Ser Pro Lys Ser Gln Thr
  65                  70            



      <210> 1946
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 1946
 Met Gly Gly Glu Arg His Pro Ser Tyr Val Gly Arg Ser Leu Pro Leu
   1               5                  10                  15    
 Leu Met Pro Leu Leu Cys Leu Leu Gln Lys His Asn Gly Gly Val Glu
              20                  25                  30        
 Leu Arg Ala Glu Ser Ser Pro His Glu Gln Gln Pro Phe Gly His Tyr
          35                  40                  45            
 Pro Ser Glu Thr Ala Ala Gln Thr Pro Gly Gly Pro Gly Gly Pro Glu
      50                  55                  60                
 Ala Gly Ser Lys Pro Glu
  65                  70



      <210> 1947
      <211> 52
      <212> PRT
      <213> Homo sapiens


      <400> 1947
 Met Val Ile Thr Thr Ile Ile Ala Ile Ile Lys Leu Leu Ile Val Thr
   1               5                  10                  15    
 Gly Cys Pro Thr Phe Leu Arg Phe Ser Ser Ala Ile Cys Asp Ser Phe
              20                  25                  30        
 Leu Ile Cys Pro Gln Leu Val Ser Val Asp Ala Val Gln Leu Leu Ile
          35                  40                  45            
 Ala Ser Gly Leu
      50        



      <210> 1948
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 1948
 Met Arg Pro Leu Leu Cys Ala Leu Thr Gly Leu Ala Leu Leu Arg Ala
   1               5                  10                  15    
 Ala Gly Ser Leu Ala Asp Asn Cys Arg Trp Pro Leu Gly Gln Pro Ile
              20                  25                  30        
 Gln Tyr Gln Gly Leu Thr Ala Thr Ser Ile Ala Arg Arg Glu Ile Lys
          35                  40                  45            
 Phe His Asn Ser Pro Tyr
      50                



      <210> 1949
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 1949
 Met Trp His Leu Lys Leu Cys Ala Val Leu Met Ile Phe Leu Leu Leu
   1               5                  10                  15    
 Leu Gly Gln Lys Lys Thr Leu Phe Leu Lys Cys Gly Pro Gly Met Met
              20                  25                  30        
 Tyr Ile Pro Gly Lys Glu Arg Thr Ala Val Thr Ser Asp Asn Ala Pro
          35                  40                  45            
 Phe Tyr Gly Ile Leu Ile Asn Cys Ile Leu Ala Gly Asp Thr Gln Val
      50                  55                  60                
 Lys Gln Ser Cys Ile Phe Asn Ile
  65                  70        



      <210> 1950
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 1950
 Met Asp Lys Thr Arg Ser Gly Lys Thr Thr Phe Val Thr Arg Val Ser
   1               5                  10                  15    
 Leu Leu Pro Ala Leu Leu Ala Leu Thr His Ser Trp Asp Ser Gln Val
              20                  25                  30        
 Arg Pro Ala Val Leu Asn Pro Leu Pro Arg His Gly Asn Ser Phe Val
          35                  40                  45            
 Ala Lys Gln His Val Ala Lys Gln Gln Pro Leu Arg Trp Leu Ile Tyr
      50                  55                  60                
 Ile Glu Val Ala Leu Ser Val Met Ser Pro Thr Val Pro Phe Pro Val
  65                  70                  75                  80
 Pro Val Cys Leu Ser Ala Ala Gln Pro Thr Asn Pro Leu Pro Glu Pro
                  85                  90                  95    
 Ala Arg Gly Ser Asp Val Cys Leu Ser Leu Phe Ser Leu Leu Leu Pro
             100                 105                 110        
 Ser Ser Val Leu Phe Gln Arg Ser Trp Ser Leu Ala Cys Ile Ala Glu
         115                 120                 125            
 Gln Ala Phe Gly Asp Gln Leu Asp Pro Gly His Pro Ser Ser Asn Asn
     130                 135                 140                
 Gly Phe
 145    



      <210> 1951
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 1951
 Met Lys Lys Ile Pro Leu Ser Ala Ile Thr Leu Thr Phe Leu Ser Gly
   1               5                  10                  15    
 Met Leu Gln Glu Tyr Leu Val Glu Leu Ala Arg Val Leu Ala Gly Ile
              20                  25                  30        
 Leu Glu Gly Leu Pro Gln Pro Gln Ala Ile Gly Glu Pro Leu Phe Ile
          35                  40                  45            
 Arg Tyr Ser Leu Ala Phe Glu Ser His Gly Ser Val Gly Ser Glu Phe
      50                  55                  60                
 Arg Leu Leu Phe Pro Lys Gly Met Phe Val Val Pro Ser His Phe Lys
  65                  70                  75                  80
 Ser Pro Val Leu Asn Pro Asp Leu
                  85            



      <210> 1952
      <211> 205
      <212> PRT
      <213> Homo sapiens


      <400> 1952
 Met Ala Gln Ser Arg Val Leu Leu Leu Leu Leu Leu Leu Pro Pro Gln
   1               5                  10                  15    
 Leu His Leu Gly Pro Val Leu Ala Val Arg Ala Pro Gly Phe Gly Arg
              20                  25                  30        
 Ser Gly Gly His Ser Leu Ser Pro Glu Glu Asn Glu Phe Ala Glu Glu
          35                  40                  45            
 Glu Pro Val Leu Val Leu Ser Pro Glu Glu Pro Gly Pro Gly Pro Ala
      50                  55                  60                
 Ala Val Ser Cys Pro Arg Asp Cys Ala Cys Ser Gln Glu Gly Val Val
  65                  70                  75                  80
 Asp Cys Gly Gly Ile Asp Leu Arg Glu Phe Pro Gly Asp Leu Pro Glu
                  85                  90                  95    
 His Thr Asn His Leu Ser Leu Gln Asn Pro Asp Thr Pro Ser Lys Leu
             100                 105                 110        
 Phe Thr Gln Asn Leu Gln Tyr Val Arg Leu Ser Thr Pro Asn His Arg
         115                 120                 125            
 Val Leu Gly Gln Ser Pro Tyr Ala Asp Leu Ala Gln Ser Trp His Arg
     130                 135                 140                
 Gly Ser Ala Ala Met Gly Glu Asn Ser Lys Gly Gly Ala Gln Gln Val
 145                 150                 155                 160
 Asp Trp Ile Leu Gly Leu Glu Leu Trp Asn Asn Gln Leu Glu Lys Ile
                 165                 170                 175    
 Tyr Pro Glu Glu Leu Ser Arg Leu His Arg Leu Glu Thr Leu Asn Leu
             180                 185                 190        
 Gln Asn Asn Arg Leu Thr Ser Arg Gly His Leu Phe Ser
         195                 200                 205



      <210> 1953
      <211> 220
      <212> PRT
      <213> Homo sapiens


      <400> 1953
 Met Val Ser Phe Val Phe Val Cys Val Phe Cys Pro Ser Cys Arg Val
   1               5                  10                  15    
 Tyr Val Ser Pro Val Arg Ser Ala Val Arg Ser Phe Val Leu Phe Val
              20                  25                  30        
 Arg Arg Val Ser Ser Phe Val Trp Phe Arg Gly Ala Pro Ala Arg Gly
          35                  40                  45            
 His Ala Gly Ala Arg Ala Gly Pro Gly Pro Ala Val Ala Ala Ala Ala
      50                  55                  60                
 Gly Gly Ser Leu Val Pro Ala Ala Arg Gln Gln His Cys Thr Gln Val
  65                  70                  75                  80
 Arg Ser Arg Arg Leu Met Lys Glu Leu Gln Asp Ile Ala Arg Leu Ser
                  85                  90                  95    
 Asp Arg Phe Ile Ser Val Glu Leu Val Asp Glu Ser Leu Phe Asp Trp
             100                 105                 110        
 Asn Val Lys Leu His Gln Val Asp Lys Asp Ser Val Leu Trp Gln Asp
         115                 120                 125            
 Met Lys Glu Thr Asn Thr Glu Phe Ile Leu Leu Asn Leu Thr Phe Pro
     130                 135                 140                
 Asp Asn Phe Pro Phe Ser Pro Pro Phe Met Arg Val Leu Ser Pro Arg
 145                 150                 155                 160
 Leu Glu Asn Gly Tyr Val Leu Asp Gly Gly Ala Ile Cys Met Glu Leu
                 165                 170                 175    
 Leu Thr Pro Arg Gly Trp Ser Ser Ala Tyr Thr Val Glu Ala Val Met
             180                 185                 190        
 Arg Gln Phe Ala Ala Ser Leu Val Lys Gly Gln Arg Arg Ala Ala Gln
         195                 200                 205            
 Pro Ala Ile Arg Lys Arg Phe Thr Glu His Gln Asp
     210                 215                 220



      <210> 1954
      <211> 445
      <212> PRT
      <213> Homo sapiens


      <400> 1954
 Met Glu Ala Leu Met Ala Arg Gly Ala Leu Thr Gly Pro Leu Arg Ala
   1               5                  10                  15    
 Leu Cys Leu Leu Gly Cys Leu Leu Ser His Ala Ala Ala Val Pro Ser
              20                  25                  30        
 Pro Ile Ile Lys Phe Pro Gly Asp Val Ala Pro Lys Thr Asp Lys Glu
          35                  40                  45            
 Leu Ala Val Gln Tyr Leu Asn Thr Phe Tyr Gly Cys Pro Lys Glu Ser
      50                  55                  60                
 Cys Asn Leu Phe Val Leu Lys Asp Thr Leu Lys Lys Met Gln Lys Phe
  65                  70                  75                  80
 Phe Gly Leu Pro Gln Thr Gly Asp Leu Asp Gln Asn Thr Ile Glu Thr
                  85                  90                  95    
 Met Arg Lys Pro Arg Cys Gly Asn Pro Asp Val Ala Asn Tyr Asn Phe
             100                 105                 110        
 Phe Pro Arg Lys Pro Lys Trp Asp Lys Asn Gln Ile Thr Tyr Arg Ile
         115                 120                 125            
 Ile Gly Tyr Thr Pro Asp Leu Asp Pro Glu Thr Val Asp Asp Ala Phe
     130                 135                 140                
 Ala Arg Ala Phe Gln Val Trp Ser Asp Val Thr Pro Leu Arg Phe Ser
 145                 150                 155                 160
 Arg Ile His Asp Gly Glu Ala Asp Ile Met Ile Asn Phe Gly Arg Trp
                 165                 170                 175    
 Gly Arg Gln Lys Met Gly Gln Lys Arg Gly Gln Gln Gly Ser Val Leu
             180                 185                 190        
 Arg Arg Gly Gly Thr Gly Val Gly Gly Asp Ser His Phe Asp Asp Asp
         195                 200                 205            
 Glu Leu Trp Thr Leu Gly Glu Gly Gln Val Val Arg Val Lys Tyr Gly
     210                 215                 220                
 Asn Ala Asp Gly Glu Tyr Cys Lys Phe Pro Phe Leu Phe Asn Gly Lys
 225                 230                 235                 240
 Glu Tyr Asn Ser Cys Thr Asp Thr Gly Arg Ser Asp Gly Phe Leu Trp
                 245                 250                 255    
 Cys Ser Thr Thr Tyr Asn Phe Glu Lys Asp Gly Lys Tyr Gly Phe Cys
             260                 265                 270        
 Pro His Glu Ala Leu Phe Thr Met Gly Gly Asn Ala Glu Gly Gln Pro
         275                 280                 285            
 Cys Lys Phe Pro Phe Arg Phe Gln Gly Thr Ser Tyr Asp Ser Cys Thr
     290                 295                 300                
 Thr Glu Gly Arg Thr Asp Gly Tyr Arg Trp Cys Gly Thr Thr Glu Asp
 305                 310                 315                 320
 Tyr Asp Arg Asp Lys Lys Tyr Gly Phe Cys Pro Glu Thr Ala Met Ser
                 325                 330                 335    
 Thr Val Gly Gly Asn Ser Glu Gly Ala Pro Cys Val Phe Pro Phe Thr
             340                 345                 350        
 Phe Leu Gly Asn Lys Tyr Glu Ser Cys Thr Ser Ala Gly Arg Ser Asp
         355                 360                 365            
 Gly Lys Met Trp Cys Ala Thr Thr Ala Asn Tyr Asp Asp Asp Arg Lys
     370                 375                 380                
 Trp Gly Phe Cys Pro Asp Gln Val Ser Thr Ile Cys Tyr Gln Gly Val
 385                 390                 395                 400
 Asn Gly Gly Ser Ser Ser Val Leu Gly Ala Glu Asp Gly Ala Asp Trp
                 405                 410                 415    
 Asp Ser Ser Leu Pro Pro Arg Thr His Lys Leu Arg Gly Glu Ser Asp
             420                 425                 430        
 Gln Glu Thr Ala Cys Asp Leu Thr Met Cys Ser Val Gln
         435                 440                 445



      <210> 1955
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 1955
 Met Arg Phe His His Val Gly Arg Ala Gly Leu Glu Leu Leu Thr Leu
   1               5                  10                  15    
 Ser Pro Glu Ala Cys Trp Gly Leu Ala Ala Gln Pro Gln Thr Lys Arg
              20                  25                  30        
 Pro Leu Cys Arg Ser Ser Pro Arg Thr Leu Arg Arg Lys Gln Leu Pro
          35                  40                  45            
 Ser Lys Arg Tyr Ser Ala Phe Thr Ala Val Thr Gln Glu Ser Leu Leu
      50                  55                  60                
 Gly Ala Gly Pro Ser Ala Gly Ser Tyr Lys Gly Leu Thr Gly Ala Gly
  65                  70                  75                  80
 Gly Gly Gly Ala Ala Asn Ser Val Arg Ile Cys Glu Gly Leu Arg Ser
                  85                  90                  95    
 Cys Glu Ile Ile Val Phe Gln Asn Val Arg Ser Val Ile Leu Ser Ile
             100                 105                 110        
 Lys Val Thr Ala Ala Met Glu Cys Lys Met Arg His Thr Gly Glu Val
         115                 120                 125            
 Glu Arg His Asp Thr Leu Pro Ser Arg Phe Ser Ser His Thr Val Asn
     130                 135                 140                
 Asn Val Pro Leu Met Asp Leu Thr Val Leu Tyr Gly Ser Ser Ile Leu
 145                 150                 155                 160
 Glu Glu Glu Val Leu Leu Ile Glu Asn Lys Arg Leu Leu Ser Asp Leu
                 165                 170                 175    
 Leu Cys Lys His Ser Pro Val Ser Cys Ser Arg Ser Gly Lys Val Ala
             180                 185                 190        
 Phe Gly His Lys Ala Ser Leu Lys Arg Lys Ala Glu Glu Lys Leu Glu
         195                 200                 205            
 Ser Tyr Gly Lys Lys Ile His Met Met Asn Asn Gln Ala Glu Glu Lys
     210                 215                 220                
 Ala Ala Asp Gln Phe Arg Met Arg Leu Lys Asn Lys Gln Asp Glu Met
 225                 230                 235                 240
 Lys Leu Glu Gly Asp His Arg Arg Ser Gln Gln Val Cys Gln Gln Leu
                 245                 250                 255    
 Asp Thr Gln Lys Asn Ile Gln Val Pro Arg Glu Ala Trp Tyr Trp Leu
             260                 265                 270        
 Arg Leu Glu Lys Glu Thr Glu Asp Glu Glu Glu Lys Glu Gln Asp Glu
         275                 280                 285            
 Asp Glu Tyr Lys Ser Glu Asp Leu Ser Val Leu Glu Lys Leu Gln Ile
     290                 295                 300                
 Leu Thr Ser Tyr Leu Arg Glu Glu Leu Leu Tyr Ser Ile Trp Cys Gly
 305                 310                 315                 320
 Thr Ala Tyr Glu Asp Lys Glu Asp Leu Ser Ser Asn Cys Pro Gly Pro
                 325                 330                 335    
 Thr Ser Gln Ile Met Thr Lys Ile Ile Pro Asn Lys Leu Glu Thr
             340                 345                 350    



      <210> 1956
      <211> 76
      <212> PRT
      <213> Homo sapiens


      <400> 1956
 Met Lys Ser Ser Ile His Asn Phe Leu Tyr Leu Trp Leu Cys Asp Phe
   1               5                  10                  15    
 Ala Ala Phe Ala Pro Thr Gly Val Val His Pro Trp Ser Asp Leu Leu
              20                  25                  30        
 Trp Pro Leu Ala Ala Cys Arg Ser Glu Glu Pro Ser Phe Trp Lys Glu
          35                  40                  45            
 Leu Leu His Ala Met Gly Thr Val Phe Val Leu Asn Val His Ser Phe
      50                  55                  60                
 Val Thr Asn Lys Trp Ser His Thr Lys Asn Arg Asn
  65                  70                  75    



      <210> 1957
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1957
 Met Thr Thr Trp Ser Leu Arg Arg Arg Pro Ala Arg Thr Leu Gly Leu
   1               5                  10                  15    
 Leu Leu Leu Val Val Leu Gly Phe Leu Val Leu Arg Arg Leu Asp Trp
              20                  25                  30        
 Ser Thr Leu Val Pro Leu Arg Leu Arg His Arg Gln Leu Gly Leu Gln
          35                  40                  45            
 Ala Lys Gly Trp Asn Phe Met Leu Glu Asp Ser Thr Phe Trp Ile Phe
      50                  55                  60                
 Gly Gly Ser Ile His Tyr Phe Arg Val Pro Arg Glu Tyr Trp Arg Asp
  65                  70                  75                  80
 Arg Leu Leu Lys Met Lys Ala Cys Gly Leu Asn Thr Leu Thr Thr Tyr
                  85                  90                  95    
 Val Pro Trp Asn Leu His Glu Pro Glu Arg Gly Lys Phe Asp Phe Ser
             100                 105                 110        
 Gly Asn Leu Asp Leu Glu Tyr Val Val Leu Leu Leu Leu
         115                 120                 125



      <210> 1958
      <211> 284
      <212> PRT
      <213> Homo sapiens


      <400> 1958
 Met Val Arg Ala Tyr Ala Met Leu Val Leu Met Cys Leu Leu Ser Gly
   1               5                  10                  15    
 Gly Asp Leu Val Ser Gly Lys Gly Glu Ser Val Asn Gln Pro Gly Ala
              20                  25                  30        
 Arg Ser Trp Gln Pro Arg Glu Leu Gln Ala Phe Asp Leu Val Pro Lys
          35                  40                  45            
 Gly Ser Ala Ser His Tyr Met Gly Leu Glu Val Phe Asp Leu His Gly
      50                  55                  60                
 His Gln Gly Gln Val Gln Gly Ile Leu Lys Leu Lys Gly Lys Glu Phe
  65                  70                  75                  80
 Leu Lys Asp Cys Arg Lys Tyr Arg Pro Gly Glu Asn Arg Met Thr Val
                  85                  90                  95    
 Arg Pro Lys Ala Val Lys Tyr Ile Gln Leu Arg Glu Ala Glu Glu Leu
             100                 105                 110        
 Pro Gly Ala Trp Asp Ile Leu Ala Ala Leu Leu Lys Met Ile Tyr Asp
         115                 120                 125            
 Phe Met Asn Leu Phe Gly Ser Ser Ser Gly Pro Gly Asp Met Thr Gly
     130                 135                 140                
 Thr Pro Gly Ala Val Ala Thr Arg Asp Gly Glu Ala Pro Glu Arg Ser
 145                 150                 155                 160
 Pro Pro Cys Ser Pro Ser Tyr Asp Leu Thr Gly Lys Leu Pro Gly Ala
                 165                 170                 175    
 Glu Val Leu Met Glu Lys Trp Val Asn Ile Val Ser Gly Pro Gly Ser
             180                 185                 190        
 Val Phe Leu Gly Lys Leu Ser Lys Gln Glu Glu Val Ala Glu Arg Gly
         195                 200                 205            
 Lys Lys Gly Pro Gly Gln Lys Thr Ile Leu Val Gly Asp Ser Gly Val
     210                 215                 220                
 Gly Lys Thr Ser Leu Leu Val Gln Phe Asp Gln Gly Lys Phe Ile Pro
 225                 230                 235                 240
 Gly Ser Phe Ser Ala Thr Val Gly Ile Gly Phe Thr Pro Cys Thr His
                 245                 250                 255    
 Lys Lys Leu Leu Ala Asp Glu Gln Ser Gly Val Ala Glu Lys Glu Arg
             260                 265                 270        
 Arg Asp Lys Gln Leu Asn Val Lys Ser Gly Ser Asn
         275                 280                



      <210> 1959
      <211> 347
      <212> PRT
      <213> Homo sapiens


      <400> 1959
 Met Gly Lys Ser Leu Arg His Ser Gly Cys Cys Leu Ser Trp Pro Ser
   1               5                  10                  15    
 Pro Thr Val Leu Leu Pro Pro Trp Leu Thr Ala Leu Thr Ala Asp Ala
              20                  25                  30        
 Gly Leu Pro Val Ala Trp Val Met Leu Phe Thr Tyr His Arg Arg Gly
          35                  40                  45            
 Gln Gln Gly Leu Ser Val Thr Gln Leu Gln His Asp Arg Glu Val Ser
      50                  55                  60                
 Thr Ser Arg Gln Pro Trp Ser Gln Asp Thr Thr Asn Val Met Asp His
  65                  70                  75                  80
 Cys Leu Met Thr His Arg Val Gly Glu Val Val Thr Gly Ala Ile Arg
                  85                  90                  95    
 Pro Thr Gly Ser Gly Ala Thr Arg Pro Val Ser Pro Arg Val Asp Ser
             100                 105                 110        
 Pro Leu Gly Met Gly Arg Arg Arg Trp Gln Phe Pro Gln Pro Ser Leu
         115                 120                 125            
 Thr Glu Lys Arg Ala Gly Glu Gln Ala Ala Ile Pro Gly Ala Gln Pro
     130                 135                 140                
 Arg Gly Thr Gln Arg Gly Ala Arg Pro Gly Pro Arg His Arg Ser Gly
 145                 150                 155                 160
 Phe Asp Ile Pro Arg Gly Arg Ala Arg Ser Arg Gln Arg Pro Glu Gly
                 165                 170                 175    
 Arg Thr Gly Pro Ala Met Pro Arg Pro Asn Arg Arg Pro Arg Phe Thr
             180                 185                 190        
 Ser Arg Ser Pro Val Pro Asp Ala Arg Pro Lys Ala Glu Arg Gly Pro
         195                 200                 205            
 Gly Pro Asp Arg Arg Arg Gln Asn Lys Thr Leu Ser Pro Ala Arg Leu
     210                 215                 220                
 Cys Ala His Asn Glu Thr Pro Gln Pro Thr Ala His Pro Thr Ala Gln
 225                 230                 235                 240
 Arg Leu Leu Gly Leu Val Val Arg Pro Val Thr Pro Pro Thr Thr Thr
                 245                 250                 255    
 Arg Ser Glu Arg Leu Gly Thr Thr Val Pro Gly Met His Arg Pro Gly
             260                 265                 270        
 Ala Ala Gly Gly Gly Gly Glu Gly Ala Pro Arg Ser Glu Val Thr Pro
         275                 280                 285            
 Arg Pro Glu Glu Ser Trp Arg Pro Asp Pro Ser Pro Gly Glu Glu Gly
     290                 295                 300                
 Ser Arg Ala Lys Pro Ser Pro Asn Ala Ser Ser Arg Leu Thr Val Pro
 305                 310                 315                 320
 Ala Ala Leu Gly Gln Arg Pro Gln Gln Gln Asp Arg Thr Pro Arg Gln
                 325                 330                 335    
 Leu Ala Val Ala Leu Leu Ser Gln Gly Gly Gly
             340                 345        



      <210> 1960
      <211> 226
      <212> PRT
      <213> Homo sapiens


      <400> 1960
 Met Arg Gly Trp Ala Arg Trp Leu Met Pro Val Ile Pro Ala Leu Trp
   1               5                  10                  15    
 Glu Ala Glu Ala Gly Glu Ser Gln Gly Asp Ile Gly Gly Val Asn Ile
              20                  25                  30        
 Gln Lys Cys Asp Cys Leu Thr Gln Pro Arg Ala Leu Ala Ile Ile Lys
          35                  40                  45            
 Arg Cys Ser Asp Gly Ala Val Gln Glu Cys Asp Ala Gly Glu Leu Glu
      50                  55                  60                
 Gln Gln Ser His Ile Ser Thr Ser Arg Pro Thr Ala Val Ser His Thr
  65                  70                  75                  80
 Leu Glu Pro Ser Phe Ala Gln Ser His Met His Asp Trp Asp Arg Gly
                  85                  90                  95    
 Phe Val Pro Phe Arg Leu Pro Met Leu Val Arg Ser Gln Thr Leu Arg
             100                 105                 110        
 Cys His Ile Gly Val Arg Ser Pro Gly Ser Ser Thr Arg Tyr Ala Ala
         115                 120                 125            
 Ala Arg Leu Lys Ser Val Cys Val Leu Pro Ala Leu Ser Gly Ile Pro
     130                 135                 140                
 Ser Ser Leu Arg Gly Thr Val Ser Leu Val Thr Ala Ala Arg Leu Pro
 145                 150                 155                 160
 Pro Gln Asp Pro Glu Asn Ala Ala His Phe Ser Trp Ala His Leu Ser
                 165                 170                 175    
 Pro Ala Arg Leu Gly Leu Arg Phe Pro Gly Asp Pro Ala Val Gln Tyr
             180                 185                 190        
 Val Ser Arg Gly Gly Ala Glu Ala Arg Glu Pro Pro Ser Glu Ala Gly
         195                 200                 205            
 Arg Gly Glu Arg Lys Leu Ala Pro Glu Asp Leu Asn Arg Gln Glu Gly
     210                 215                 220                
 Leu Gly
 225    



      <210> 1961
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 1961
 Met Lys Leu Ser Ala Phe Leu Ala Val Ala Ser Leu Asn Ile Trp Lys
   1               5                  10                  15    
 Thr Thr Ser Glu Ala Ala Leu Ser Val Val Asn Glu Lys Thr Gln Ala
              20                  25                  30        
 Val Val Asn Glu Lys Thr Gln Ala Pro Leu Asp Cys Asp Asn Ser Ala
          35                  40                  45            
 Asp Ser Leu Arg Val Phe Ala Asp Ser Ser Ile Gly Glu Asn Trp Thr
      50                  55                  60                
 Leu Gln Met Val Cys Asp Pro Asp Thr Trp Met Arg Gly Pro Arg Ser
  65                  70                  75                  80
 Val Val Phe Arg Thr Pro Phe Cys
                  85            



      <210> 1962
      <211> 200
      <212> PRT
      <213> Homo sapiens


      <400> 1962
 Met Glu Lys Glu Leu Ile Phe Ser Pro Trp Arg Val Phe Leu Lys Leu
   1               5                  10                  15    
 Leu Ile Leu Ser Val Ser Ala Val Arg Gly Gly Ala Ala Gln Ser Arg
              20                  25                  30        
 Gly Trp Leu Gln Thr Glu Gly Val Val Asp Ser Val Asp Leu Asn Cys
          35                  40                  45            
 Cys Pro Ser Phe Gln Ala Phe Pro Val Asn Glu Pro Glu Asn Thr Arg
      50                  55                  60                
 Gln Val Val Asn Asn Arg Phe Asn Glu Cys Ala Lys Arg Ala Thr Gly
  65                  70                  75                  80
 His Thr Phe Gly Pro Pro Pro Glu Leu Arg Cys Pro Arg Val Thr Ala
                  85                  90                  95    
 Phe Cys Asp Arg Val Arg Arg Asp Pro Val Pro Leu Ser Pro Ser Val
             100                 105                 110        
 Phe Arg Glu Gly Glu Ala Leu Arg Ile Ser Gly Ala Val Gln Gln Pro
         115                 120                 125            
 Arg Pro His Pro Arg Gly Ser Arg Pro Arg Gly Pro Phe Thr Ser Pro
     130                 135                 140                
 Ser Gly Leu Gly Asp Ala Asn Ser Pro Lys Lys Thr Leu Ala Glu Glu
 145                 150                 155                 160
 Arg Gly Pro Phe Thr Thr Asn Leu Thr Ser Gly Leu Gln Pro His Leu
                 165                 170                 175    
 Gly Thr Ser Ser Glu Lys Leu Arg Asn His Cys Phe Ala Lys Ser Leu
             180                 185                 190        
 Leu Tyr Cys Asp Gly Ala Leu Trp
         195                 200



      <210> 1963
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 1963
 Met Ala Ser Cys Leu Gly Leu Leu Ile Leu Ser Ser Cys Leu Leu Ala
   1               5                  10                  15    
 Asp Cys Arg Phe Ile Pro Glu Ala Trp Ser Ala Cys Thr Val Thr Cys
              20                  25                  30        
 Gly Val Gly Thr Gln Ser Val Ala Asp Leu Pro Ile Asp Glu Cys Glu
          35                  40                  45            
 Gly Pro Lys Pro Ala Ser Gln Arg Ala Cys Tyr Ala Gly Pro Cys Ser
      50                  55                  60                
 Gly Glu Ile Pro Glu Phe Asn Pro Asp Glu Thr Asp Gly Leu Phe Gly
  65                  70                  75                  80
 Gly Leu Gln Asp Phe Asp Glu Leu Tyr Asp Trp Glu Tyr Glu Gly Phe
                  85                  90                  95    
 Thr Lys Cys Ser Glu Ser Cys Gly Gly Val Ala Leu Arg Leu Ser Ala
             100                 105                 110        
 Val Ser Gly Gln Tyr Asn Lys Cys Phe Gly Phe Gln Leu Ser Phe
         115                 120                 125        



      <210> 1964
      <211> 245
      <212> PRT
      <213> Homo sapiens


      <400> 1964
 Met Pro Leu Val Ile Ile Ile His Phe Leu Ala Met Asn Trp Ile Ile
   1               5                  10                  15    
 Pro Gly Thr Ser Ser Lys Pro Thr Leu Gly Lys Gly Ser Tyr Val Val
              20                  25                  30        
 Ala Ala Ser Asp Phe Lys Gly Arg Thr Phe Lys Val Val Gly Ala Ser
          35                  40                  45            
 Ala Arg Val Val Phe Val Phe Ala Glu Arg Leu Phe Ala Val Leu His
      50                  55                  60                
 Leu Leu Ala Ser Phe Asp Gly Pro Gln Gly Pro Ser Gln Gly Lys Ser
  65                  70                  75                  80
 Gln Glu Ser Leu Gly Met Tyr Ser Glu Ser Phe Gln Ala Phe His Ser
                  85                  90                  95    
 Asn Ala Val Ile Phe Pro Pro Pro Ser Ser Lys Gly Ser Ser Lys Thr
             100                 105                 110        
 Asp Asn Thr Ser Arg Leu Ser Val Pro Lys Lys Thr Arg Ser Ile Val
         115                 120                 125            
 Phe Lys Ser Ser Pro Leu Val Trp Val Asp Gln Pro Ser Pro Leu Asp
     130                 135                 140                
 Gly Met Gly Thr Gln Ile Pro His Leu Thr Asp Ser Arg Met Gly Leu
 145                 150                 155                 160
 Arg Lys Gly Trp Asp Glu Ala Glu Ala Ala Leu Ser Asp Val Pro Cys
                 165                 170                 175    
 Val Gln Leu Ser Cys Asp Ile Leu Glu Lys Arg Leu Ser Gln Leu Arg
             180                 185                 190        
 Ser Arg Ser Ser Leu Glu Pro Arg Ile Ala Pro Thr Phe Pro Ala His
         195                 200                 205            
 Phe Gln Ile Gln Phe Glu Pro Pro Arg Ala Cys Ser Ala Pro Glu Glu
     210                 215                 220                
 Arg Glu Pro Ala Ser Pro Val Leu Gln Arg Trp Lys Cys Ser Val Leu
 225                 230                 235                 240
 Tyr Arg Pro Val Gln
                 245



      <210> 1965
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 1965
 Met Val His Cys Ser Gly Pro Pro Arg Cys Leu Phe Leu Tyr Ser Ala
   1               5                  10                  15    
 Ala Leu Ser Gln Phe Leu Phe Ala Phe Glu Asp Pro Thr Asp His Met
              20                  25                  30        
 Ser Gln Leu Thr Trp Met Val Leu Pro Gln Arg Phe Arg Asp Ser Leu
          35                  40                  45            
 His Leu Phe Gly Gln Ala Leu Ala His Ser Leu Gly His Phe Ser Ser
      50                  55                  60                
 Pro Gly Thr Leu Ile Leu Gln Tyr Val Asp Asp Leu Leu Leu Ala Thr
  65                  70                  75                  80
 Ser Ser Glu Ala Leu Cys Gln Gln Ala Thr Val Glu Leu Leu Asn Phe
                  85                  90                  95    
 Leu Ala Asn Gln Gly Ser Ala Arg Gln Gly Val His Lys Pro Ala Lys
             100                 105                 110        
 Ala Leu Cys Leu Cys Ala Gln His Pro Ala Ala Val Thr Gly Ala Pro
         115                 120                 125            
 Glu Ala Arg Trp Gln Gln Gly Glu Ala Ala Gln Cys Ser Ala Gln Lys
     130                 135                 140                
 Lys Asn Ser Ala Val Thr Ala Glu Gln Ser Ser Thr Ala Ile Ser Glu
 145                 150                 155                 160
 His Lys Asp Cys Gly Lys Ala Ser Asn Pro Thr Cys
                 165                 170        



      <210> 1966
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 1966
 Met Lys Arg Ile Leu Trp Lys Ser Ile Arg Met Ile Val Cys Gly Cys
   1               5                  10                  15    
 Leu Glu Leu Gln Met Thr Ile Ala Pro Leu Asn Gln Lys Ala Ala Leu
              20                  25                  30        
 His Leu Met Leu Leu Trp Val Ile Lys Pro Ser Leu Gly Leu Tyr Asn
          35                  40                  45            
 Thr Gly Cys Asn His Leu Lys Ser Gly Arg Gly Ile Asn Pro Gln Leu
      50                  55                  60                
 Arg Leu Glu Lys Glu Lys Ala Glu Trp Phe Met Val Leu Asp Leu Lys
  65                  70                  75                  80
 Asp Ala Phe Phe Cys Ile Ser Leu His Ser Asp Ser Gln Phe Leu Phe
                  85                  90                  95    
 Asp Phe Glu Asp Pro Thr Asp His Thr Ser Gln Leu Thr Trp Thr Val
             100                 105                 110        
 Leu Pro Gln Gly Phe Arg Asp Ser Pro His Leu Phe Gly Gln Ala Leu
         115                 120                 125            
 Ala Gln Asp Leu Gly His Phe Ser Ser Pro Asp Thr Leu Val Leu Gln
     130                 135                 140                
 Tyr Val Asp Asp Leu His Leu Ala Thr Ser Leu Glu Ala Ser Cys Gln
 145                 150                 155                 160
 Gln Ala Thr Leu Asp Leu Leu Asn Phe Leu Ala Asn Gln Glu Tyr Met
                 165                 170                 175    
 Met Ser Arg Leu Arg Ala Pro Leu Cys Leu Glu Gln Val Glu Tyr Leu
             180                 185                 190        
 Ala Leu Ile Leu Ala Arg Gly Thr Arg Ala Ile Ser Lys Glu Gln Ile
         195                 200                 205            





      <210> 1967
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 1967
 Met Ser Leu Val Cys Leu Ile Gly Phe Trp Arg Gln His Ile Pro His
   1               5                  10                  15    
 Leu Gly Val Leu Leu Gln Pro Ile Tyr Arg Met Thr Gln Lys Ala Ala
              20                  25                  30        
 Ser Phe Glu Trp Gly Leu Glu Gln Glu Lys Ser Leu Gln Gln Val Gln
          35                  40                  45            
 Ala Ala Val Gln Ala Ala Leu Pro Leu Gly Leu Tyr Asp Ile Ala Glu
      50                  55                  60                
 Pro Met Val Leu Glu Val Pro Val Ala Asp Arg Asp Ala Val Cys Ser
  65                  70                  75                  80
 Leu Trp Gln Ala Pro Ile Gly Asn Tyr Ser Pro Phe Glu Arg Gln Leu
                  85                  90                  95    
 Leu Ala Cys Tyr Trp Ala Leu Val Glu Thr Glu Arg Leu Thr Met Gly
             100                 105                 110        
 His Gln Val Thr Met Gln Pro Glu Leu Pro Ile Met Asn
         115                 120                 125



      <210> 1968
      <211> 462
      <212> PRT
      <213> Homo sapiens


      <400> 1968
 Met Trp His Phe Ile Ile Leu Phe Gln Glu Thr Ala Thr Ala Thr Leu
   1               5                  10                  15    
 Thr Thr Ser Leu Leu Asn Gln Gln Pro Ser Thr Ser Arg Leu Phe Gln
              20                  25                  30        
 Ala Cys Val Val Phe Ile Leu Pro Val Ser Ala Tyr Asn Val Thr Phe
          35                  40                  45            
 Ser Val Thr Ile Val Leu Arg Pro Ile Arg Gly Val Asn Pro Leu Ser
      50                  55                  60                
 Cys Lys Ser Gly Thr Gly Leu His Pro Thr Arg Ala Leu Ala Asp Cys
  65                  70                  75                  80
 Leu Ile Val Leu Trp Phe Thr Pro Gln Leu Thr Ser Ile Thr Gly Met
                  85                  90                  95    
 Ser Asp Leu Lys Ile His Leu Leu Leu Val Asn Ala Ser Asn Ile Glu
             100                 105                 110        
 Phe Tyr Gly Lys Pro Leu Ile Leu Asn Asp Arg Glu Lys Tyr Ser Leu
         115                 120                 125            
 Thr Phe Leu Ser Glu Ser Asn Thr Thr Met Glu Val Gly Tyr Glu Ile
     130                 135                 140                
 Asp Leu Glu Ser Tyr Glu Gln Asn Phe Phe Lys Arg Glu Ile Glu Trp
 145                 150                 155                 160
 Asn Arg Lys Ser Trp Trp Ser Glu Glu Ala His Leu Gln Ala Gln Leu
                 165                 170                 175    
 Asn Arg Thr Asn Gly Ile Leu Ile Thr Gln Ala Gln Leu Thr Gly Ser
             180                 185                 190        
 Asp Ser Phe Ser Asn Thr Tyr Ala Gln Leu Gly Phe Asp Ala Leu Thr
         195                 200                 205            
 Thr Lys Gln Ala Thr Lys Leu Cys Met Arg Ala Tyr Asn Lys Leu Arg
     210                 215                 220                
 Ala Pro Gly Gln Pro Ser Ala Ser Phe Thr Thr Val Lys Gln Ala Gln
 225                 230                 235                 240
 Leu Leu Leu Leu Pro Asn Ile Ile Leu Asn Lys Gly Gly Lys Thr Arg
                 245                 250                 255    
 Gly Pro Arg Met Gly Ser Asp Gly Glu Lys Ala Ala Tyr Trp Ile Asn
             260                 265                 270        
 Val Ile Ser Lys Gln Trp Pro Thr Tyr Thr Ile His Ile Gln Val Lys
         275                 280                 285            
 Lys Phe Glu Gly Leu Val Asp Thr Gly Ala Glu Ile Asn Ile Pro His
     290                 295                 300                
 Asn Ser Tyr Ser Ala Pro Ser Gln His Thr Met Glu Asn Met Gly Phe
 305                 310                 315                 320
 Val Pro Gly Leu Gly Leu Ser Pro Lys His Glu Gly Ile Thr Lys Ser
                 325                 330                 335    
 Leu Pro Val Thr Val Lys Glu Asn Arg Ala Val Ser Ser His Thr Asp
             340                 345                 350        
 Leu Pro Ala Thr Gln Asn Tyr Ser Tyr Trp Ala Tyr Val Pro Phe Pro
         355                 360                 365            
 Pro Leu Ile Arg Pro Leu Thr Trp Ile Asp Ala Pro Ala Glu Ile Tyr
     370                 375                 380                
 Thr Asn Asp Ser Val Trp Met Pro Gly Ala Thr Asp Asp Cys Cys Pro
 385                 390                 395                 400
 Ala Gln Pro Gly Glu Gly Thr Ala Phe Asn Val Thr Met Gly Tyr Lys
                 405                 410                 415    
 Tyr Pro Pro Leu Cys Leu Gly His Ala Pro Gly Cys Ile His Leu Glu
             420                 425                 430        
 Thr Gln Val Trp Ala Ala Tyr Leu Pro Glu Ile Ser Ala Thr Glu Glu
         435                 440                 445            
 Pro Gly Tyr Leu Ile Ser Gly Leu Ser Leu Ser Pro Leu Lys
     450                 455                 460        



      <210> 1969
      <211> 262
      <212> PRT
      <213> Homo sapiens


      <400> 1969
 Met Lys Phe Leu Ala Ala Val Leu Phe Pro Phe Cys Phe Pro Lys Gly
   1               5                  10                  15    
 Gly Lys Lys Lys Pro Val Asn Phe Lys Asn Pro Tyr Pro Ala Phe Ile
              20                  25                  30        
 Phe Ser Tyr Leu Glu Ser Glu Leu Asn His His Gly Asn Val Gln Ile
          35                  40                  45            
 Phe Phe Ser Ser Ser Leu Lys Val Gln Trp Ser Tyr Leu Lys Arg Phe
      50                  55                  60                
 Ser Tyr Gln Lys Gly Gly Ile Trp Met Ser Gly Gly Glu Glu Lys Val
  65                  70                  75                  80
 Gln Thr Leu His Gln Thr His Ala Ala Ala Lys Lys Pro Gln Ser Val
                  85                  90                  95    
 Gly Ile Cys Val Arg Gln Lys Gly Arg Gln Lys Ala Gly Leu Glu Lys
             100                 105                 110        
 Gly Asn Arg Lys Lys Glu Leu Arg Gln Ala Asn Cys Pro Ser Leu Arg
         115                 120                 125            
 Pro Gln Arg Lys Gly Ala Asp Thr Arg Arg Leu Pro Arg Glu Thr Arg
     130                 135                 140                
 Pro Thr Lys Lys Arg Thr Ala Ala Ala Gln Pro Phe Leu Gln Leu Trp
 145                 150                 155                 160
 Asn Pro Ala Pro His Thr Ser Asn Gly Arg Thr Asp Ser Thr Ala Ile
                 165                 170                 175    
 Arg Thr Pro Ala Arg Ala Lys Asp Pro Ile Thr Ala Gly Ala Leu Glu
             180                 185                 190        
 Arg Val Ser Gln Thr Gln Gly His Gly Gln Val Pro Asp Gln Ile Leu
         195                 200                 205            
 Gln Ala Leu Leu Ser Ala Ala Trp Gln Thr Ala Ser Ser His Thr Asp
     210                 215                 220                
 Val Arg Gly Ser Arg Leu Thr Gln Gly Pro Ile Leu Asp Leu Phe Ser
 225                 230                 235                 240
 Val Thr Asp Ile Glu Ala Glu Ala Thr Gly Pro Ala Val Gln Phe Thr
                 245                 250                 255    
 Ala Leu Gly Ala Leu Asp
             260        



      <210> 1970
      <211> 438
      <212> PRT
      <213> Homo sapiens


      <400> 1970
 Met Lys Arg Arg Asp Trp Pro Ser Leu Pro Ala Tyr Ile Phe Leu Pro
   1               5                  10                  15    
 Cys Trp Met Leu Pro Ala Leu Glu His Gln Thr Pro Ser Ser Ser Val
              20                  25                  30        
 Leu Arg Leu Arg Leu Ala Leu Leu Ala Pro Gln Thr Cys Arg Gln Thr
          35                  40                  45            
 Ile Val Gly Pro Cys Asp Cys Ile Ser Thr Leu Ile Arg Tyr Ile Asp
      50                  55                  60                
 Asp Ser Met Leu Ile Gly Ser Ser Glu Gln Glu Val Ala Asn Thr Leu
  65                  70                  75                  80
 Asp Leu Phe Val Arg His Leu His Ala Arg Glu Trp Glu Ile Lys Leu
                  85                  90                  95    
 Thr Lys Ile Gln Gly Pro Ser Thr Ser Val Lys Phe Leu Gly Val Gln
             100                 105                 110        
 Trp Tyr Gly Ala Cys Gln Asp Ile Pro Ser Asn Val Lys Asp Thr Leu
         115                 120                 125            
 Leu His Leu Ala Pro Pro Ile Thr Lys Lys Glu Ala Gln Cys Leu Leu
     130                 135                 140                
 Gly Leu Phe Gly Phe Trp Arg Gln His Ile Pro His Leu Glu Leu Pro
 145                 150                 155                 160
 Ile Lys Asn Trp Val Leu Ser Asp Pro Ser Ser Tyr Lys Val Gly Cys
                 165                 170                 175    
 Ala Gln Gln Tyr Ser Ile Ile Lys Trp Lys Trp Tyr Ile Cys Asp Trp
             180                 185                 190        
 Ala Gln Ala Asn Pro Glu Gly Thr Ile Asn Gly Leu Ala Arg Trp Ser
         195                 200                 205            
 Gly Thr Trp Lys Lys His Asn Trp Lys Ile Gly Asp Lys Glu Ile Trp
     210                 215                 220                
 Gly Arg Gly Met Trp Met Asp Leu Ser Glu Trp Ser Lys Thr Val Lys
 225                 230                 235                 240
 Ile Tyr Val Ser His Val Ser Ala His Gln Gln Met Thr Ser Ala Glu
                 245                 250                 255    
 Glu Asp Phe Asn Asn Gln Val Asp Arg Met Thr Arg Ser Met Asp Thr
             260                 265                 270        
 Thr Gln Pro Leu Ser Pro Thr Thr Pro Val Ile Thr Gln Trp Ala His
         275                 280                 285            
 Glu Gln Ser Asp His Gly Gly Arg Asp Gly Asp Tyr Thr Trp Ala Gln
     290                 295                 300                
 Gln His Gly Leu Pro Leu Thr Lys Ser Phe Thr Phe Ala Lys Glu Val
 305                 310                 315                 320
 Trp Gln Trp Ala His Ala His Gly Ile His Trp Ser Tyr Val Pro His
                 325                 330                 335    
 His Pro Glu Ala Ala Gly Leu Ile Glu Arg Trp Asn Gly Leu Leu Lys
             340                 345                 350        
 Ser Gln Leu Lys Cys Gln Leu Gly Asp Asn Thr Leu Gln Gly Trp Gly
         355                 360                 365            
 Lys Val Leu Gln Lys Ala Ile Ile Lys Ala Glu Lys Leu Gln Met Val
     370                 375                 380                
 Leu Gln Met Glu Pro Gln Met Gln Ser Met Thr Lys Ile Tyr His Gly
 385                 390                 395                 400
 Pro Leu Asp Arg His Ala Ser Pro Cys Ser Asp Val Asn Asp Ile Lys
                 405                 410                 415    
 Ala Thr Pro Pro Lys Glu Ile Ser Thr Ala Arg Pro Leu Leu Arg Pro
             420                 425                 430        
 Asn Ser Ala Gly Ser Ser
         435            



      <210> 1971
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 1971
 Met Leu Ile Gln Gly Ser Ala Trp Trp Cys Gly Thr Ile Ile Leu Lys
   1               5                  10                  15    
 Phe Leu Thr Ser Lys Ile Leu Gly Val Ser Asp His Ile Arg Leu Ser
              20                  25                  30        
 Asp Leu Ile Ala Ala Arg Ile Leu Arg Tyr Thr Asp Phe Asp Thr Leu
          35                  40                  45            
 Ile Tyr Thr Cys Ala Pro Glu Phe Asp Phe Met Glu Lys Ala Val
      50                  55                  60            



      <210> 1972
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 1972
 Met Arg Lys Ala Ser Trp Pro Leu His Leu Thr Ser Thr Ala Ala Ala
   1               5                  10                  15    
 Trp Val Ile Lys Ala Ala Gly Ala Asp Thr Thr Glu Asn Arg Arg Lys
              20                  25                  30        
 Asn Arg Thr Val Pro His Val Arg Val Leu His Ser Pro Gln Thr Leu
          35                  40                  45            
 Ser Phe Glu Pro Gly Val Val His Trp Ser Met Gly Ala Gln Asp Leu
      50                  55                  60                
 Thr Thr Ile Ser Met Leu Val Gly Leu Pro Arg Leu Cys Val Trp Trp
  65                  70                  75                  80
 Ser Leu Ser Cys Arg Lys Gln Trp Val Leu Trp Asn Arg Leu Cys Gly
                  85                  90                  95    
 Ala Gly Arg Cys Cys Ser Arg Thr Thr Ala Ala Asp Cys Leu Gly Lys
             100                 105                 110        
 Ala Ser Gly Ser Lys Ser Cys Ser Met Met Asp Val Thr Leu Leu Asp
         115                 120                 125            
 Glu His Gly Lys Pro Phe Trp Cys Phe Ser Ser Pro Val Cys Leu Arg
     130                 135                 140                
 Ser Pro Ala Thr Pro Ser Asp Ser Ser Ser Phe Leu Gly Gln Thr Tyr
 145                 150                 155                 160
 Asn Val Asp Tyr Val Asp Ala Glu Gly Arg Val His Val Glu Leu His
                 165                 170                 175    
 Leu Gly Ala Cys Gln Val Leu His Asn Arg Tyr Ser Ile Thr Ile Cys
             180                 185                 190        
 Gln Thr Asn Gly Asn Arg Tyr Arg Asp Ile Pro Ala Ala Met Gly Ala
         195                 200                 205            





      <210> 1973
      <211> 233
      <212> PRT
      <213> Homo sapiens


      <400> 1973
 Met Arg Phe Val Met Ser Val Thr Met Tyr His Thr Thr Leu Val Gly
   1               5                  10                  15    
 Leu Asp Ile Lys His Leu Asn Leu Glu Ser Gly Lys Val Trp Val Met
              20                  25                  30        
 Gly Lys Ala Ser Lys Glu Pro Arg Leu Pro Ile Gly Arg Asn Ala Val
          35                  40                  45            
 Ala Trp Ile Glu His Trp Leu Asp Leu Arg Asp Leu Phe Gly Ser Lys
      50                  55                  60                
 Asp Asp Ala Leu Phe Leu Ser Lys Leu Gly Lys Arg Ile Ser Ala Arg
  65                  70                  75                  80
 Asn Val Gln Lys Arg Phe Ala Glu Trp Gly Ile Lys Gln Gly Leu Asn
                  85                  90                  95    
 Asn His Val His Pro His Lys Leu Arg His Ser Phe Ala Thr His Met
             100                 105                 110        
 Leu Glu Ser Ser Gly Asp Leu Arg Gly Leu Phe Arg Phe Val Ser Ala
         115                 120                 125            
 Lys Arg His Ala Lys Gly Ser Lys Val Gly Ser Pro Ile Ile Tyr Ala
     130                 135                 140                
 Asp Gln Ile Ile Ile Gly Ala Gly Gln Asn His Pro Ala Arg Trp Arg
 145                 150                 155                 160
 Gly Leu Pro Arg Lys Ser Arg Leu Leu Val Ser Pro Ser Asn Asp Lys
                 165                 170                 175    
 Arg Arg Lys Ala Gly Ala Ala Pro Val Ala Ala Leu Arg His Phe Pro
             180                 185                 190        
 Pro Ile Ser Ile Glu Asn Ala Ile Val Lys Ile Gln Phe Arg Ile Ile
         195                 200                 205            
 Arg Arg Leu Asn His Gln Gln Leu Val Lys Pro Tyr Pro Gln Val Pro
     210                 215                 220                
 Ile Ser Gln Ala Thr Asn Gln Phe Arg
 225                 230            



      <210> 1974
      <211> 331
      <212> PRT
      <213> Homo sapiens


      <400> 1974
 Met Val Phe Ala Ser Ile Leu Leu Leu Met Ala Leu Val Val Leu Pro
   1               5                  10                  15    
 Ile Ala Trp Gln Gln Gly Ile Tyr Leu Ile Arg Asp Met Pro Gly Met
              20                  25                  30        
 Leu Asn Asn Leu Ser Asp Phe Ala Val Thr Leu Pro Cys Arg Tyr Pro
          35                  40                  45            
 Ser Leu Met Asp Ala Gly Ile Ile Asp Ala Met Ala Ala Asn Met Arg
      50                  55                  60                
 Ser Pro Met Leu Ser Met Cys Asp Phe Gly Val Lys Ile Ser Leu Cys
  65                  70                  75                  80
 Ser Met Ala Gly Leu Leu Thr Ile Ala Cys Tyr Leu Val Leu Val Pro
                  85                  90                  95    
 Leu Met Asp Ile Leu Leu Leu Asn Asp Lys Glu Glu Met Leu Lys Pro
             100                 105                 110        
 His Arg Pro Gly Leu Thr Arg Tyr Gln Gly Leu Ala Arg Gln Leu Gly
         115                 120                 125            
 Thr Leu Asp Glu Ile Asp Glu Leu Thr Leu Glu Leu Gln Pro Lys Leu
     130                 135                 140                
 Leu Arg Val Leu Gln Glu Arg Glu Ile Glu Arg Ile Gly Gly Ser Arg
 145                 150                 155                 160
 Thr Ile Pro Ala Asn Val Arg Val Ile Ala Ala Thr Asn Arg Asp Leu
                 165                 170                 175    
 Trp Gln Met Gly Glu Asp Arg Gln Phe Arg Ser Asp Leu Phe Tyr Arg
             180                 185                 190        
 Leu Asn Val Phe Pro Leu Glu Leu Pro Pro Leu Arg Asp Arg Ala Glu
         195                 200                 205            
 Asp Ile Pro Leu Leu Ala Lys His Phe Thr His Lys Met Ala Arg His
     210                 215                 220                
 Met Asn Arg Ala Arg Asp Ala Ile Pro Thr Glu Ala Leu Arg Gln Leu
 225                 230                 235                 240
 Met Ser Gly Asp Trp Pro Arg Asn Val Arg Glu Leu Glu Asn Val Ile
                 245                 250                 255    
 Glu Arg Thr Leu Leu Val Thr Arg Gly Asn Ser Leu Asn Leu His Leu
             260                 265                 270        
 Asn Val Arg Gln Arg Arg Leu Leu Pro Thr Leu Asn Glu Asp Ser Ala
         275                 280                 285            
 Leu Arg Arg Ser Met Ala Gln Val Leu His Pro Thr Thr Ser Glu Asn
     290                 295                 300                
 Asp Glu Glu Glu Arg Leu Cys Ile Gly Gln Ala Leu Arg Glu Thr Asn
 305                 310                 315                 320
 Gly Ile Val Ala Arg Pro Arg Gly Ala Leu Thr
                 325                 330    



      <210> 1975
      <211> 266
      <212> PRT
      <213> Homo sapiens


      <400> 1975
 Met Gly Arg Arg Arg Ala Arg Trp Trp Leu Glu Ala Pro Cys Met Trp
   1               5                  10                  15    
 Ser Leu Val Pro Leu His Ala Ala Ser Arg Ser Gln Arg Ile Pro Pro
              20                  25                  30        
 Glu Leu Asp Thr Gln Leu Arg Pro Lys His Leu Asp Val Ser Ala Leu
          35                  40                  45            
 Asp Thr Pro Thr Leu Ala Leu Ala Asn Ala Ala Arg Glu Thr Leu Arg
      50                  55                  60                
 Ile Gly Asp Ala Met Glu Gln Met Met Glu Gly Leu Asn Lys Val Met
  65                  70                  75                  80
 His Gly Glu Pro Arg Gln Glu Lys Glu Leu Arg Lys Leu Ala Asp Asp
                  85                  90                  95    
 Ile Asn Val Leu Tyr Thr Ala Ile Lys Leu Tyr Leu Ala Arg Met Pro
             100                 105                 110        
 Lys Glu Glu Leu Ala Glu Glu Glu Ser Arg Arg Trp Ala Glu Ile Ile
         115                 120                 125            
 Glu Met Ser Leu Asn Leu Glu Gln Ala Ser Asp Ile Val Glu Arg Met
     130                 135                 140                
 Gly Ser Glu Ile Ala Asp Lys Ser Leu Ala Ala Arg Arg Ala Phe Ser
 145                 150                 155                 160
 Leu Asp Gly Leu Lys Glu Leu Asp Ala Leu Tyr Glu Gln Leu Leu Ser
                 165                 170                 175    
 Asn Leu Lys Leu Ala Met Ser Val Phe Phe Ser Gly Asp Val Thr Ser
             180                 185                 190        
 Ala Arg Arg Leu Arg Arg Ser Lys His Arg Phe Arg Ile Leu Asn Arg
         195                 200                 205            
 Arg Tyr Ser His Ala His Val Asp Arg Leu His Gln Gln Asn Val Gln
     210                 215                 220                
 Ser Ile Glu Thr Ser Ser Leu His Leu Gly Leu Leu Gly Asp Met Gln
 225                 230                 235                 240
 Arg Leu Asn Ser Leu Phe Cys Ser Val Ala Tyr Ser Val Leu Glu Gln
                 245                 250                 255    
 Pro Asp Glu Asp Glu Gly Arg Asp Glu Tyr
             260                 265    



      <210> 1976
      <211> 477
      <212> PRT
      <213> Homo sapiens


      <400> 1976
 Met Pro Gly Leu Leu Asn Trp Ile Thr Gly Ala Ala Leu Pro Leu Thr
   1               5                  10                  15    
 Ala Ser Asp Val Thr Ser Cys Val Ser Gly Tyr Ala Leu Gly Leu Thr
              20                  25                  30        
 Ala Ser Leu Thr Tyr Gly Asn Leu Glu Ala Gln Pro Phe Gln Gly Leu
          35                  40                  45            
 Phe Val Tyr Pro Leu Asp Glu Cys Thr Thr Val Ile Gly Phe Glu Ala
      50                  55                  60                
 Val Ile Ala Asp Arg Val Val Thr Val Gln Ile Lys Asp Lys Ala Lys
  65                  70                  75                  80
 Leu Glu Ser Gly His Phe Asp Ala Ser His Val Arg Ser Pro Thr Val
                  85                  90                  95    
 Thr Gly Asn Ile Leu Gln Asp Gly Val Ser Ile Ala Pro His Ser Cys
             100                 105                 110        
 Thr Pro Gly Lys Val Thr Leu Asp Glu Asp Leu Glu Arg Ile Leu Phe
         115                 120                 125            
 Val Ala Asn Leu Gly Thr Ile Ala Pro Met Glu Asn Val Thr Ile Phe
     130                 135                 140                
 Ile Ser Thr Ser Ser Glu Leu Pro Thr Leu Pro Ser Gly Ala Val Arg
 145                 150                 155                 160
 Val Leu Leu Pro Ala Val Cys Ala Pro Thr Val Pro Gln Phe Cys Thr
                 165                 170                 175    
 Lys Ser Thr Gly Thr Ser Asn Gln Gln Ala Gln Gly Lys Asp Arg His
             180                 185                 190        
 Cys Phe Gly Ala Trp Ala Pro Gly Ser Trp Asn Lys Leu Cys Leu Ala
         195                 200                 205            
 Thr Leu Leu Asn Thr Glu Val Ser Asn Pro Met Glu Tyr Glu Phe Asn
     210                 215                 220                
 Phe Gln Leu Glu Ile Arg Gly Pro Cys Leu Leu Ala Gly Val Glu Ser
 225                 230                 235                 240
 Pro Thr His Glu Ile Arg Ala Asp Ala Ala Pro Ser Ala Arg Ser Ala
                 245                 250                 255    
 Lys Ser Ile Ile Ile Thr Leu Ala Asn Lys His Thr Phe Asp Arg Pro
             260                 265                 270        
 Val Glu Ile Leu Ile His Pro Ser Gly Thr Val Pro His Asn Gly Pro
         275                 280                 285            
 Leu Gly Cys Leu Trp Glu Gly Gly Glu Pro His Met Pro His Val Leu
     290                 295                 300                
 Ile Glu Lys Gly Asp Met Thr Leu Gly Glu Phe Asp Gln His Leu Lys
 305                 310                 315                 320
 Gly Arg Thr Asp Phe Ile Lys Gly Met Lys Lys Lys Ser Arg Ala Glu
                 325                 330                 335    
 Arg Lys Gly Ser Val Ile Lys Arg Ala Arg Leu Gly Cys Gly Leu Trp
             340                 345                 350        
 Trp Ser Gly Phe Thr Trp Glu Arg Asp Ser Glu Ile Pro Trp Gln Gly
         355                 360                 365            
 Glu Glu Trp Val Val Gly Ile His Arg Val Asn Ile Asn Gln Glu Glu
     370                 375                 380                
 Trp Thr Glu Ile Ile Arg Lys Arg Leu His Lys Asp Ile Pro His His
 385                 390                 395                 400
 Ser Val Ile Met Leu Asn Phe Cys Pro Asp Leu Gln Ser Val Gln Pro
                 405                 410                 415    
 Cys Leu Arg Lys Ala His Gly Glu Phe Ile Phe Leu Ile Asp Arg Ser
             420                 425                 430        
 Ser Ser Met Ser Gly Ile Ser Met His Arg Val Lys Val Pro Ser Leu
         435                 440                 445            
 Ala Leu Gly His Leu Glu Lys Gln Gln Asn Val Asn Thr Phe Ala Val
     450                 455                 460                
 Leu Lys Glu Leu Thr Val Lys Arg Glu Ala Gln Ala Cys
 465                 470                 475        



      <210> 1977
      <211> 187
      <212> PRT
      <213> Homo sapiens


      <400> 1977
 Met Gly Leu Leu Leu Phe Pro Lys Pro Ala Cys Phe Arg Val Ser Ala
   1               5                  10                  15    
 Leu Ala Val Pro Ser Gly Cys Met Pro Cys Gly Glu Asn Val Met Leu
              20                  25                  30        
 Glu Gln Arg Gln Pro Ser Glu Thr Met Arg Arg Gly Thr Ala Asp Thr
          35                  40                  45            
 His Arg Val Gln Cys Gly Arg Gly Asn Ile Trp Ala Ser Ile Met Thr
      50                  55                  60                
 Leu Gln Thr Ala Asn Val Ser Met Leu Lys Leu Ala Pro Ser Trp Ser
  65                  70                  75                  80
 Leu Glu His Ser Arg Ala Trp Arg Thr Ala Gly Pro Pro Arg Ala Phe
                  85                  90                  95    
 Val Glu Arg Met Asn Ala Ala Arg Ser His Trp Met Gly Ala Val Gln
             100                 105                 110        
 Arg Leu Met Lys Ile Ile Met Leu Asn Tyr Arg Leu Val Ala His Phe
         115                 120                 125            
 Leu Val Leu Phe Ala Gln Lys Lys Ala Asn Arg Gln Arg Thr Arg Val
     130                 135                 140                
 His Arg Gly Ser Leu Trp Leu Ser Glu Cys Glu Ser Pro Asn Gly Pro
 145                 150                 155                 160
 Gly Gly Arg His Thr Glu Pro Ala Glu Gly Arg Gln Ala Arg Gly Arg
                 165                 170                 175    
 Thr Pro Gln Gln Gly Phe Ala Val Ser Leu Met
             180                 185        



      <210> 1978
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 1978
 Met Asn Lys His Phe Leu Phe Leu Phe Leu Leu Tyr Cys Leu Ile Val
   1               5                  10                  15    
 Ala Val Thr Ser Leu Gln Cys Ile Thr Cys His Leu Arg Thr Arg Thr
              20                  25                  30        
 Asp Arg Cys Arg Arg Gly Phe Gly Val Cys Thr Ala Gln Lys Gly Glu
          35                  40                  45            
 Ala Cys Met Leu Leu Arg Ile Tyr Gln Arg Asn Thr Leu Gln Ile Ser
      50                  55                  60                
 Tyr Met Val Cys Gln Lys Phe Cys Arg Asp Met Thr Phe Asp Leu Arg
  65                  70                  75                  80
 Asn Arg Thr Tyr Val His Thr Cys Cys Asn Tyr Asn Tyr Cys Asn Phe
                  85                  90                  95    
 Lys Leu
        



      <210> 1979
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 1979
 Met Thr Ala Gly Thr Val Val Ile Thr Gly Gly Ile Leu Ala Thr Val
   1               5                  10                  15    
 Ile Leu Leu Cys Ile Ile Ala Val Leu Cys Tyr Cys Arg Leu Gln Tyr
              20                  25                  30        
 Tyr Cys Cys Lys Lys Ser Gly Thr Glu Val Ala Asp Glu Glu Glu Glu
          35                  40                  45            
 Arg Glu His Asp Leu Pro Thr His Pro Arg Gly Pro Thr Cys Asn Ala
      50                  55                  60                
 Cys Ser Ser Gln Ala Leu Asp Gly Arg Gly Ser Leu Ala Pro Leu Thr
  65                  70                  75                  80
 Ser Glu Pro Cys Ser Gln Pro Cys Gly Gln Ser Thr Thr Ala Ala Val
                  85                  90                  95    
 Ser Ser Leu Pro Glu Ile Thr Ser Phe Val Arg Pro Ala Phe Val Lys
             100                 105                 110        
 Ile Lys Thr Gln Leu Thr Ile Thr His Phe Leu Pro Leu Ile Asp Gly
         115                 120                 125            
 Val Pro Glu Tyr Lys Arg Pro Val Gln Ser Pro Pro Ser Tyr Arg Phe
     130                 135                 140                
 Pro Ser
 145    



      <210> 1980
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 1980
 Met Leu His Thr Arg Arg Val Cys Ile Phe Thr Leu Leu Pro Cys Leu
   1               5                  10                  15    
 Thr Lys Pro Ala Leu Leu Ala Met Glu Thr Thr Leu Thr Ser Leu Leu
              20                  25                  30        
 Leu Gly Glu Gln Gly Arg Ser Asp Ala Leu Ala Leu Ala Lys His Gln
          35                  40                  45            
 Gly Lys Val Gly Ser Lys Gly His Gln His Leu Leu Lys Val Lys Val
      50                  55                  60                
 Thr Arg Lys Leu Gln Val Val Lys Ala Arg Val Tyr Gly Ser Asn Lys
  65                  70                  75                  80
 Leu Ser Thr Leu Ser Gly Asp His Arg Val Gln Trp Leu Arg Leu Gly
                  85                  90                  95    
 Ala Gln Glu Pro Phe Tyr Leu Gly Val Asp Ala Gly Ser Asn Ser Tyr
             100                 105                 110        
 Lys Tyr Leu
         115



      <210> 1981
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 1981
 Met Leu Met Phe Val Ile Phe Val Ile Tyr Thr Lys Ser Glu Leu Val
   1               5                  10                  15    
 Phe Leu Pro Asn Trp Lys Pro Ser Cys Leu Asn Tyr Asp Asp Ile Ser
              20                  25                  30        
 Asn Ile Phe Tyr Leu Phe Gly Val Tyr Leu Glu Pro Arg Lys Ile Met
          35                  40                  45            
 Gly Gly Asn Asn Ser Ser Leu Leu Asp
      50                  55        



      <210> 1982
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 1982
 Met Asn Arg Val Met Arg Gly Leu Ala Ile Thr Thr Thr Cys Leu Leu
   1               5                  10                  15    
 Ser Met Leu Gln Ala Ile Thr Ile Ser Pro Ser Ile Leu Trp Asn His
              20                  25                  30        
 Ala Ala Val Gln Tyr Val His Gly His Ser Leu Val Gln Ala
          35                  40                  45    



      <210> 1983
      <211> 391
      <212> PRT
      <213> Homo sapiens


      <400> 1983
 Met Gly Leu Leu Pro Arg Ser Pro Leu Trp Leu Ala Val Ala Leu Pro
   1               5                  10                  15    
 Gly Gln Pro Arg Ala Val Ala Val Gly Ala His Ser Met His Phe Phe
              20                  25                  30        
 Asn Lys Arg Thr Gln Lys Ala Leu Ala His Arg Cys Cys Ser Ala Ser
          35                  40                  45            
 Leu Leu Gln His Asp Tyr Pro Glu Ala His Pro Cys Arg Gly Leu Pro
      50                  55                  60                
 Val Val Tyr Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Gly Met
  65                  70                  75                  80
 Pro Val Cys Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Gly Met
                  85                  90                  95    
 Pro Val Cys Ala Pro Val Leu Trp Arg Ala Arg Arg Leu Cys Thr Arg
             100                 105                 110        
 Ala Val Val Cys Pro Ser Ser Val His Pro Cys Arg Gly Val Pro Val
         115                 120                 125            
 Val Cys Ala Pro Val Leu Trp Val Ala Pro Thr Cys Ala Ser Gln Arg
     130                 135                 140                
 Arg Thr Pro Gly Ser Pro Val His Arg Ser Val Gly Ile Trp Val Val
 145                 150                 155                 160
 Ser Val Trp Gly Ile Tyr Lys Lys Arg Ala Arg Thr Phe Val Tyr Lys
                 165                 170                 175    
 Ser Cys Val Asn Leu Ser Ser Phe Leu Leu Gly Lys Tyr Leu Cys Val
             180                 185                 190        
 Glu Gln Leu Gly His Val Val Asn Gln His Val Val Trp Leu Val Phe
         195                 200                 205            
 Phe Val Ala Ala Ser Pro Leu Gly Ala Leu Gly Met Trp Leu Gln Leu
     210                 215                 220                
 Asp Leu Gly Phe Leu Val Pro Gly Lys Val Glu His Leu Phe Met Cys
 225                 230                 235                 240
 Phe Phe Ala Val Cys Gly Ser Cys Gly Glu Arg Asp Ala Ser Leu Thr
                 245                 250                 255    
 Pro Trp Leu Phe Arg Lys Val Trp Gly Gln Ala Cys Cys Thr Tyr Cys
             260                 265                 270        
 Phe Gly Leu Met Ile Gln Arg Val Lys Gly Ala Phe Ser Pro Glu Glu
         275                 280                 285            
 Gly Ala Lys Ala Phe Ala Gly Asp Asp Thr Leu Thr Lys Val Ser His
     290                 295                 300                
 Ala Leu Ser Lys Lys Thr Asp Gly Gln Arg Gly Cys Ile Leu Gly Gly
 305                 310                 315                 320
 Gly Leu Pro Gly Asn His Val Gly Pro Gly Pro Glu Asn His Pro Leu
                 325                 330                 335    
 Ala Ser Ser Ser Trp Gln Val Ser Ser Asn Pro Val Leu Ala Asp Arg
             340                 345                 350        
 Thr Phe Cys Asn Asp Gly Asn Val Leu Tyr Leu Asp Asn Pro Leu Ala
         355                 360                 365            
 Gln Met Thr Thr Gly Tyr Trp Lys Cys Gly His Lys Glu Pro Asn Phe
     370                 375                 380                
 Ser Leu Cys Phe Ile Val Ile
 385                 390    



      <210> 1984
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 1984
 Met Leu Met Leu Ile Leu Val Thr Gly Val Ser Ser Leu Arg Asn Met
   1               5                  10                  15    
 Ile Met Cys Asp Tyr Ile Ser Arg Ala Lys Leu Lys Ser Ser His Ile
              20                  25                  30        
 Val Leu Ser Tyr Cys Ser Leu Lys Gln Glu Tyr Asp Asp Ser Arg Gly
          35                  40                  45            
 Val Met Asn Leu Glu Ala Arg Glu Glu Gly Ser Arg Gly Phe Tyr Cys
      50                  55                  60                
 Leu Gly Cys Ile Asp Thr Gly Leu Gln Thr Pro Gly Gly Arg Gly Pro
  65                  70                  75                  80
 Ser Ser Ala Leu Val Thr Ser Val His Leu Ala Cys Glu Glu Tyr Thr
                  85                  90                  95    
 Phe His Arg Glu Ile Glu Asp Asp Ala Asp
             100                 105    



      <210> 1985
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 1985
 Met Ala Thr Cys Met Pro Val Leu Arg Val Leu Leu Cys Met Cys Ala
   1               5                  10                  15    
 Leu Pro Trp Met Lys Gly Arg Ser Asp Lys Ser Lys Leu Lys Lys Leu
              20                  25                  30        
 Thr Ser Glu Gly Gln Trp Asn Gly Ile Leu Val Gln Phe Pro Gln Lys
          35                  40                  45            
 Glu Asp Phe Leu Val Pro Arg Asp Lys Ile Asn Met Asn Trp Gly Ala
      50                  55                  60                
 Gly Ala Gly Leu Gln Arg Glu Phe Ala Ala Ser Ala Arg Asn Val Ala
  65                  70                  75                  80
 Thr Arg Pro Arg Asn Ala Cys Ser Pro Arg Phe Leu Leu Ser Arg Val
                  85                  90                  95    
 Pro Ser Val Arg Asp Pro Thr Gly Asn Arg Thr Val Gln Leu Thr Trp
             100                 105                 110        
 Gln Pro Leu Pro Glu Ser Leu Glu Leu Trp Pro Lys Ala Leu
         115                 120                 125    



      <210> 1986
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 1986
 Met Val Asp Met Phe Gly Lys Lys Ala Phe Phe Leu Cys Cys Gly Leu
   1               5                  10                  15    
 Ala Ile Leu Ala Phe Gln Ala Ile Leu Val Leu Gln Ile Ser Leu Ile
              20                  25                  30        
 Asn His Ile Arg Phe Leu Asp His Pro Lys Ile Lys Glu Val Lys Pro
          35                  40                  45            
 Ala Ser Asn Asp Cys Ser Val Trp Val Tyr Lys Gly Leu Ala Pro Leu
      50                  55                  60                
 Pro Val Pro Pro Tyr Leu Leu Ala Asn Gly Leu Arg Leu Ala Leu
  65                  70                  75                



      <210> 1987
      <211> 241
      <212> PRT
      <213> Homo sapiens


      <400> 1987
 Met Val Asn Pro Thr Met Leu Gly Leu Thr Val Arg Leu Met Val Gly
   1               5                  10                  15    
 Pro Cys Val Ser Phe Glu Leu Leu Ala Asp Lys Phe Pro Lys Thr Ala
              20                  25                  30        
 Glu Lys Phe Arg Ala Leu Ser Pro Gly Glu Glu Gly Phe Gly Tyr Lys
          35                  40                  45            
 Gly Ser Cys Phe His Arg Ile Ile Pro Gly Phe Met Cys Gln Gly Gly
      50                  55                  60                
 Asp Phe Thr Leu His Asn Gly Thr Gly Gly Asn Ser Ile Tyr Gly Glu
  65                  70                  75                  80
 Lys Leu Asp Asp Glu Asn Phe Ile Leu Lys His Ile Gly Gln Leu Trp
                  85                  90                  95    
 Ile Cys Arg Pro Lys Gly Glu Lys Glu Gly Glu Pro Pro Leu Pro Gly
             100                 105                 110        
 Leu Cys Ser Leu Arg Pro Ser Asn Val Gln Glu Gly Gln Glu Gln Asn
         115                 120                 125            
 Leu Arg Gly Ser Cys Val Met Ala Leu Ser Thr Gly Glu Thr Arg Gln
     130                 135                 140                
 Tyr Gly Leu Trp Ser Gln Ala Asn Arg Ser Leu Gln Pro Ser Tyr Gly
 145                 150                 155                 160
 Thr Asp Arg Leu Cys Asp Ser Gly Lys Leu Leu His Leu Ser Glu Pro
                 165                 170                 175    
 Gln Arg Thr His Met Gln Thr Glu Thr Ile Ala Arg Leu Val Ser Val
             180                 185                 190        
 Ile Ser Asn Thr Leu Gln Met Arg Gly Thr Met His Gly His Arg Thr
         195                 200                 205            
 Thr His Ser Pro Gln Thr Asp Thr Leu Phe Glu Ser Trp Thr Pro Ala
     210                 215                 220                
 Thr Val Glu Pro Ser Ser Pro Pro Asp Gly Lys Val Pro Phe Thr Gly
 225                 230                 235                 240
 Leu
    



      <210> 1988
      <211> 455
      <212> PRT
      <213> Homo sapiens


      <400> 1988
 Met Trp Leu Ser Pro Ser Leu Leu Leu Leu Ile Leu Pro Ala Ala Leu
   1               5                  10                  15    
 Ser Asp Ala Gly Val Val Leu Gly Ala Gly Ser Leu Val Leu Pro Ser
              20                  25                  30        
 Asn Ala Gln Arg Gln Pro Tyr Ala Gln Pro Gly Pro Gln Leu Pro Gly
          35                  40                  45            
 Ala Glu Val Leu Met Glu Lys Trp Val Asn Ile Arg Gln Gln Leu Asp
      50                  55                  60                
 Ser Ala Arg Ala Gly Phe Ala Gly Lys Leu Tyr Arg His Phe Glu Gly
  65                  70                  75                  80
 Cys Val Gly Ala Pro Gly Ile Lys Glu Gly Arg Leu Ser Gln Ser Ala
                  85                  90                  95    
 Gln Ala Ala Ile Thr Lys Ile Pro Gln Ile Gly Trp Leu Thr Gln Lys
             100                 105                 110        
 Lys Phe Ile Ser Pro Ser Ser Gly Gly Trp Lys Phe Lys Ile Lys Met
         115                 120                 125            
 Leu Ala Glu Ser Val Pro Gly Thr Phe His Tyr Asn Pro Ile Arg Lys
     130                 135                 140                
 Ser Lys Leu Arg Pro Pro Ser Lys Thr Glu Leu Thr Gln Lys Leu Ser
 145                 150                 155                 160
 Ser Gly Ser Lys Leu Lys Ser Asn Pro Ile Lys Gly Asn Ser Arg Leu
                 165                 170                 175    
 Ser Leu Lys Leu Leu Pro Val Glu Leu His Arg Ala Gln Glu Ile Ser
             180                 185                 190        
 Ser Ser Ile Asp Lys Arg Asn Leu Glu Ala Leu Phe Ile Ser Tyr Ile
         195                 200                 205            
 Leu Glu Arg Ile Val Gln Gly Gln Lys Gln Lys Arg Arg Gln Arg Arg
     210                 215                 220                
 Arg Thr Ser Pro Leu Gln Thr Cys Glu Glu Ser Cys Ala Ala Leu Ser
 225                 230                 235                 240
 Cys Val Val Thr Glu Met Pro Val Arg Ser Gly Ser Gly Thr Val Ser
                 245                 250                 255    
 Ser Trp Asp Arg Asn Ala Leu Arg Thr Gln Pro Ala Ser Trp Ser Pro
             260                 265                 270        
 Lys Arg Gln Gly Leu Glu Arg Thr Gly Ser Gln Asn Ser Gly Pro Gly
         275                 280                 285            
 Arg Thr Thr Ala Glu Ser Leu Phe Leu Val Leu Lys Arg Ser Val Leu
     290                 295                 300                
 Glu Glu Arg Gly Arg Leu Pro Ala Trp Tyr Arg Ala Ala Ala Ala Ala
 305                 310                 315                 320
 Gly Asn Cys Pro Val Leu Lys Thr Asp Ala Ala Arg Pro Ala Glu Leu
                 325                 330                 335    
 Arg Pro Lys Pro Ala Ala Pro Ser Gly Ala Arg Thr Glu Leu Leu Glu
             340                 345                 350        
 Ala Leu Thr Gln Ser Ala Gly Arg Ala Gly Ala Ala Ser Ser Lys Pro
         355                 360                 365            
 Gly Met Asp Leu Gln Arg Pro Asp Ser Tyr Gln Gly Gly Ala Gly Pro
     370                 375                 380                
 Asp Phe Asn Asp His Val Leu His Lys Ala Arg Glu Thr Val Cys Arg
 385                 390                 395                 400
 Asp Cys Glu Cys Glu Trp Arg Ser Gln Leu Leu Val Asn Ser Leu Arg
                 405                 410                 415    
 Gln Cys Ser Ser Gln Leu Gly Val Ala Leu Asp Ile Leu Leu Ser Leu
             420                 425                 430        
 Asn Gln Arg Arg Phe Ser Gly Ala Lys Arg Asp Ser Ser Lys Gln Thr
         435                 440                 445            
 Asp Leu Glu Asn Ile Asn Pro
     450                 455



      <210> 1989
      <211> 183
      <212> PRT
      <213> Homo sapiens


      <400> 1989
 Met Lys Arg Gln Asp Trp Pro Ile Leu Pro Ala Tyr Ile Phe Leu Leu
   1               5                  10                  15    
 Cys Trp Met Leu Pro Ala Leu Glu His Gln Thr Pro Ser Ser Ser Val
              20                  25                  30        
 Leu Arg Leu Glu Leu Thr Phe Leu Leu Leu Lys Leu Ala Gly Ser Leu
          35                  40                  45            
 Leu Arg Asp Ile Val Ile Val Ser His Pro Ser Pro Asn Thr Gln Leu
      50                  55                  60                
 Arg Leu Ser Gly Pro Thr Arg Gly Pro Arg Leu Ala Pro Thr Ala Arg
  65                  70                  75                  80
 Glu Leu Phe Arg Gly Glu Ala Ala Gly Gly Glu Ala Ala Ala Pro Ala
                  85                  90                  95    
 Leu Pro His Leu His Arg Asn Arg Pro Phe Arg Asp Val Thr Asp Asn
             100                 105                 110        
 Ala Phe Trp Ile Pro Val Cys Ser Ser Ala Ser Pro Asn Ala Pro Gln
         115                 120                 125            
 Trp Ser Asn Pro Leu Ser Glu Pro Ala Gly Glu Val Thr Tyr Ala Cys
     130                 135                 140                
 Pro Phe Phe Leu Ser Cys Pro Arg Pro Ser Ser Pro Ala Met Lys Arg
 145                 150                 155                 160
 Val Phe Asn Leu Cys Pro Val Glu Val Pro Phe Gly Gly Gln Leu Glu
                 165                 170                 175    
 Ala Arg Ala Pro Phe Phe Lys
             180            



      <210> 1990
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 1990
 Met Thr Thr Ser Val Val Glu Lys Leu Gln Trp Val Val Val Ala Leu
   1               5                  10                  15    
 Val Ala Ala Val Val Val Val Asp Met Val Ala Val Gly Met Ala Ile
              20                  25                  30        
 Met Asp Leu Val Met Met Val Val Met Glu Glu Ala Ala Leu Val Thr
          35                  40                  45            
 Leu Glu Glu Ala Glu Ala Met Gln Val Val Asp Arg Val Met Glu Thr
      50                  55                  60                
 Arg Ala Val Ala Met Ala Gly Val Ala Ala Met Thr Ala Ile Thr Thr
  65                  70                  75                  80
 Glu Ala Glu Ala Ala Leu Ala Val Val Val Val Gly Ile Gln
                  85                  90                



      <210> 1991
      <211> 218
      <212> PRT
      <213> Homo sapiens


      <400> 1991
 Met Pro Arg Gly Leu Leu Leu Val Leu Pro Ala Pro Ala Leu Gly Ser
   1               5                  10                  15    
 Arg Gln Leu Gly Pro Arg Cys Trp Gln Ala Gln Pro Asp Leu Ala Leu
              20                  25                  30        
 Arg Arg Arg Pro Arg Gly Pro Pro Ala Arg Pro Leu Leu Glu Leu Gly
          35                  40                  45            
 Trp Glu Trp Ala Pro Gly Leu Gly Thr Arg Arg Val Ala Ala Ser Pro
      50                  55                  60                
 Leu Arg Asp Cys Gly Thr Pro Ser Ser Gly His Leu His Thr Gly Thr
  65                  70                  75                  80
 Pro Ser Arg Ala Leu Asn Ser Arg Ala Asp Pro Ala Gly Pro Gly Ala
                  85                  90                  95    
 Gln Ser Leu Asp Ser Gly His Leu Val Leu Pro Met Leu Leu Ser Glu
             100                 105                 110        
 Gly Ser Ser Arg Thr Arg Ser Val Pro Pro Glu Asn Gly His Arg Gly
         115                 120                 125            
 Arg Leu Leu Lys Gly Pro Gly Pro Ser Leu Ala Val Glu Leu Arg His
     130                 135                 140                
 His Thr Gln Val Ser Gly Ile Asp Gly Ala Gly Gly Ser Thr Leu Gly
 145                 150                 155                 160
 Leu Leu Gln Met Arg Phe Pro Pro Ala Val Asp Gly Pro Trp Val Pro
                 165                 170                 175    
 Pro Arg Gly Trp Ser Phe Thr Ser Glu Thr Val His Ser Val Ala Ala
             180                 185                 190        
 Arg Ser Leu Leu Leu Pro Phe Val Leu Tyr Ser Gly Thr Tyr Ser Gly
         195                 200                 205            
 Pro Gly Leu Val Gln Asp Gly Gln Gly Leu
     210                 215            



      <210> 1992
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 1992
 Met Pro Val Leu Pro Val Ala Ile Ala Leu Ala Thr Leu Trp Thr Leu
   1               5                  10                  15    
 Arg Arg Lys Cys Ala Gly Leu Gly Lys Lys Gly Ser Pro Gln Leu Val
              20                  25                  30        
 Leu Arg Ala Gly Ala Arg Ile Val Leu Thr Arg Ser Arg His Ser Met
          35                  40                  45            
 Glu Glu Glu Phe Thr Thr Asp Glu Ala Asp Glu Thr Arg Ser Asn Glu
      50                  55                  60                
 Thr Gln Asn Pro His Lys Pro Ser Pro Ser Arg Leu Ser Thr Gly Ala
  65                  70                  75                  80
 Ser Ala Asp Ala Val Trp Asp Asn Gly Ile Asp Asp Ala Tyr Phe Leu
                  85                  90                  95    
 Glu Ala Thr Glu Asp Ala Glu Leu Ala Glu Ala Ala Glu Asn Ser Leu
             100                 105                 110        
 Leu Ser Tyr Asn Ser Glu Val Asp Glu Ile Pro Asp Glu Leu Ile Ile
         115                 120                 125            
 Glu Val Leu Gln Glu
     130            



      <210> 1993
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 1993
 Met Glu His Val Ala His Val Pro Leu Glu Ile Ser Glu Gly Gly Gly
   1               5                  10                  15    
 Leu Val Glu Asp Pro Thr Pro Ala Ala Glu Trp Ala Leu Pro Leu Gly
              20                  25                  30        
 Ser Val Thr Leu Thr Leu Lys Val Leu Leu Leu Leu His Leu Leu Leu
          35                  40                  45            
 Ile Leu Glu Ser Ser Ala Leu Leu Gln Ile Val Asn Cys Val Val Arg
      50                  55                  60                
 Val Ala Ser Leu Val Val Ala Lys Cys Leu Gln Gln Phe Gln Ala Ser
  65                  70                  75                  80
 Asp Leu His Ile Met Thr Ser Gly Ala Ser Ala Ile Ser Pro Thr Thr
                  85                  90                  95    
 Lys Trp Glu Pro Ser His Asn Ser Ala Cys Thr Gln Pro Gln Ser Thr
             100                 105                 110        
 Thr Leu Ala Arg Val Pro Cys Trp Leu Leu Ser Gly Glu Glu Gly Gly
         115                 120                 125            
 Glu Met Lys His Pro Gln Lys Cys Ser Lys Ala Ala Met Ala Val Thr
     130                 135                 140                
 Leu Val Ala Gln Thr Arg Glu Ala Gly Ser Pro Gln Arg Val His Leu
 145                 150                 155                 160
 Glu Thr Tyr Ala Pro Ile Tyr Cys Ala Gln His Arg Ser Phe Leu Leu
                 165                 170                 175    
 Gly Asp Thr Pro Ser Ser Gly Ala Glu Glu Ala Lys Glu Val Pro Ser
             180                 185                 190        
 Pro Leu Ser Gly Ser Leu Thr Phe Pro His Leu Pro Pro Lys Asp Ile
         195                 200                 205            
 Arg Arg Ile Asn Gly Ile Thr Asp Val Met Pro Pro Arg Lys Arg Ala
     210                 215                 220                
 Thr
 225



      <210> 1994
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 1994
 Met Leu Arg Trp Val Tyr Ile Ile Cys Ala Ile Cys Asn Cys Tyr Ile
   1               5                  10                  15    
 Pro Gly Ile Asn Asp Thr His Thr Glu Ile Leu Glu Asn Val Leu Tyr
              20                  25                  30        
 Asp Glu Ile Leu Asn Val Thr Met Lys Val Thr Lys Ser Phe Cys Ile
          35                  40                  45            
 Ile Val His Leu Pro Asp Val Phe Cys Phe Asp Asp Asn His Ser Val
      50                  55                  60                
 Trp Ala Ser Gln Lys Lys Met Leu Asn Gly Phe Val Asp Ile Glu Gly
  65                  70                  75                  80
 Pro Ser Asp Lys Asn Ile Asn Gly Lys Gly Ser Glu Met Leu Ala Gln
                  85                  90                  95    
 Gly Asn Asn Asn Asp Ser Ile Phe Phe Ser Ser Ser Ser Val Asn Gly
             100                 105                 110        
 Pro Asp Lys Pro Asp Glu Gln Ser Ala Asp Arg Thr Glu Thr Val Asn
         115                 120                 125            
 Lys Ser Ser Arg Lys Lys Lys Pro Phe Lys Trp Val
     130                 135                 140



      <210> 1995
      <211> 78
      <212> PRT
      <213> Homo sapiens


      <400> 1995
 Met Gly Phe Gly Leu Val Leu Ala Pro Leu Cys Asn Gln Phe Ile Leu
   1               5                  10                  15    
 Gly Pro His Cys Ile Asp Asp Ala Val Gln Val Gln Gly Thr Val Ile
              20                  25                  30        
 Val His Gly Gln Asp Asp Val Gly Val Ala Asp Asp Asp Lys Val Ile
          35                  40                  45            
 Leu Ala Ala Ser Pro Leu Val Asp Phe Ile Leu Ile Pro Val Arg Arg
      50                  55                  60                
 Gly Lys Gly Ala Gln Lys Gly Cys Arg Leu Thr Leu Ala Pro
  65                  70                  75            



      <210> 1996
      <211> 158
      <212> PRT
      <213> Homo sapiens


      <400> 1996
 Met Val Ala Tyr Leu Lys Ser Leu Gln Ser Gly Leu Thr Leu Leu Pro
   1               5                  10                  15    
 Phe Leu Phe Asn Ala Glu Gly Leu Gly Ala Val Arg Val Asn Leu Thr
              20                  25                  30        
 Gly Gly Met Gln Leu Phe Asp Phe Ser Ser Arg Asp Gly Val His Leu
          35                  40                  45            
 Met Glu Asp Val Glu Val Ser Arg Ser Leu Val Pro Glu Trp Asn Glu
      50                  55                  60                
 Trp Gly Leu Gly Gly Ser Leu Gly Thr Gln Leu Gly Gly Ser Phe Arg
  65                  70                  75                  80
 Trp Ser Pro Thr Gly Glu Ala Ser Lys Glu Ile Gln Ser Ser Gly Lys
                  85                  90                  95    
 Gln Asn Ala Lys Ala Ser Val Ala Gly Pro Ile Ile Ser Leu Gln Gly
             100                 105                 110        
 Gly Val Ser Arg Glu Asp Gly Met Gly Lys Asn Pro Asp Asp Ser Lys
         115                 120                 125            
 Ala Lys Ile Ser Thr Leu Val Gly Leu Leu Ser Asp His Ile Lys Asn
     130                 135                 140                
 Ser Gly Pro Tyr Glu Ser Pro Lys Leu Thr Val Asp Val Val
 145                 150                 155            



      <210> 1997
      <211> 251
      <212> PRT
      <213> Homo sapiens


      <400> 1997
 Met Gly Lys Lys Leu Ser His Leu Gly Val Gly Val Leu Ser Val Thr
   1               5                  10                  15    
 Ala Gln Phe Ala Leu Leu Ala Ala Leu Gln Ile Asn Ala Phe Leu Ser
              20                  25                  30        
 Ser Ala Ala Asn Leu Gly Val Asp Val Leu Ala Leu Leu Cys Gln Phe
          35                  40                  45            
 Phe Leu Trp Pro Asn Leu Thr Leu Thr Thr Thr Gly Ser Thr Ser Gln
      50                  55                  60                
 Thr Phe Arg Lys Ala Leu Glu Gln Phe Pro Glu Arg Ile Pro Ser Gly
  65                  70                  75                  80
 Thr Ile Arg Gln Ile Pro Gln Ser Ala Pro Asp Ile Ile Lys Lys Leu
                  85                  90                  95    
 Gln Lys Leu Glu Thr Gly Pro Gln Thr Pro Gln Gln Glu Leu Ile Asn
             100                 105                 110        
 Leu Ala Phe Lys Val Tyr Asn Asn Arg Glu Glu Ala Ala Arg Gln Gln
         115                 120                 125            
 Arg Ile Ser Glu Leu Gln Leu Leu Ala Ser Ala Met Arg Gln Asn Pro
     130                 135                 140                
 Ala Thr Pro Pro Ala His Lys Asn Phe Lys Met Pro Lys Leu His Lys
 145                 150                 155                 160
 Pro Lys Pro His Thr Pro Lys Pro Gln Gln Ser Ser Ile Pro Thr Gly
                 165                 170                 175    
 Leu Pro Pro Thr Gly Ser Cys Phe Lys Cys Gln Lys Ser Gly His Trp
             180                 185                 190        
 Ala Lys Glu Cys Pro Gln Pro Gly Ile Pro Pro Lys Pro Cys Pro Ile
         195                 200                 205            
 Cys Ala Gly Thr His Trp Lys Ser Asp Cys Pro Ala Leu Pro Ala Ala
     210                 215                 220                
 Thr Ser Arg Ala Pro Lys Ala Leu Ala Gln Gly Ser Leu Thr Asp Ser
 225                 230                 235                 240
 Phe Pro Asp Leu Leu Gly Leu Val Val Glu Asp
                 245                 250    



      <210> 1998
      <211> 186
      <212> PRT
      <213> Homo sapiens


      <400> 1998
 Met Ala Gln His Arg Cys Ala Leu Cys Val Cys Ala Ile Phe Arg Leu
   1               5                  10                  15    
 Arg Thr Ala Asn Pro Pro Gly Ser Glu Leu Phe Arg Asp Val Ala Ile
              20                  25                  30        
 Val Phe Ser Gln Glu Glu Trp Gln Trp Leu Ala Pro Ala Gln Arg Asp
          35                  40                  45            
 Leu Tyr Arg Asp Val Met Leu Glu Thr Tyr Ser Asn Leu Val Ser Leu
      50                  55                  60                
 Gly Leu Ala Val Ser Lys Pro Asp Val Ile Ser Phe Leu Glu Gln Gly
  65                  70                  75                  80
 Lys Glu Pro Trp Met Val Glu Arg Val Val Ser Gly Gly Leu Cys Pro
                  85                  90                  95    
 Gly Asn Ser Met Asn Val Arg Asn Val Gly Arg Leu Leu Ile Lys Ala
             100                 105                 110        
 Gln Leu Leu Tyr Asp Ile Arg Glu Phe Ile Pro Val Arg Asn Pro Met
         115                 120                 125            
 Ser Ala Lys His Glu Tyr Asn Asp Met Met Thr Pro Val Thr Thr Pro
     130                 135                 140                
 Thr Tyr Phe Leu Phe Leu Ile Tyr Arg Lys Pro Ile Gly Ile Phe Arg
 145                 150                 155                 160
 Asn Ser Thr Asp Glu Ala Cys Asp Phe Lys Leu Pro Asn Val Lys Leu
                 165                 170                 175    
 Glu Pro Val Ile His Asn Thr Leu Phe His
             180                 185    



      <210> 1999
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 1999
 Met Val Lys Ile Leu Gly Val Val Trp Arg Val Asn Gly Arg Cys Phe
   1               5                  10                  15    
 Ser Gly Leu Leu Pro Val Gly Leu Gly Val Ala Trp Glu His Arg Val
              20                  25                  30        
 Gly Glu Ile Lys Leu Lys Glu Asp Phe Val Gly Leu Leu Arg Arg Ser
          35                  40                  45            
 Gly Ser Ile Ser Leu Gln Leu Leu Ser Arg Glu Asp Leu Gly Ser Ser
      50                  55                  60                
 Gln Arg Ala Leu Gly Gln Ser Ser Gly Ala Leu Gly Val Ala Ala Arg
  65                  70                  75                  80
 Tyr Gln His Val Met Lys Asn Lys Gln Glu Glu Arg Glu Gly Glu Glu
                  85                  90                  95    
 Ala Gly Gly Gly Gly Glu Lys Glu Arg Glu Glu Glu Glu Glu Lys Lys
             100                 105                 110        
 Met Val Val Glu Glu Glu Glu Lys Lys Lys Lys Glu Glu Lys Glu Lys
         115                 120                 125            
 Glu Lys Lys Glu Gln Glu Glu Glu Glu Glu Glu Glu Glu Glu Lys Gly
     130                 135                 140                
 Thr His Met Gln Ser Gln Gln Lys Val Thr Trp Pro Asn Glu Phe Gly
 145                 150                 155                 160
 Asp Ser Asn Pro Ala Ser Tyr Leu Glu Glu Cys Lys
                 165                 170        



      <210> 2000
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 2000
 Met Ala Gly Arg Glu Ser Thr Arg Leu Glu Pro Val Leu Ala Leu Leu
   1               5                  10                  15    
 Ser Leu Val Cys Gly Thr Val Gly Lys Pro Arg Lys Leu Leu Glu His
              20                  25                  30        
 Ser Ser Ser Val Leu Ala Asp Thr Val Ile Ser Pro Ser Leu His Gln
          35                  40                  45            
 Pro Lys Ala Lys Thr Asp Gln Lys Ser Asn Thr Leu Leu Leu Pro Gly
      50                  55                  60                
 Pro Phe His Pro Gln Gln Val Ala Gly Tyr Ala Cys Pro Gly Lys Ala
  65                  70                  75                  80
 Leu Ala
        



      <210> 2001
      <211> 385
      <212> PRT
      <213> Homo sapiens


      <400> 2001
 Met Gly Val Lys Leu Gly Leu Trp Ser Ile Val Val Gly Leu Glu Thr
   1               5                  10                  15    
 Gly Ser Val Glu Asp Gly Leu Lys Pro Glu Ser Thr Glu Asn Ser Gln
              20                  25                  30        
 Ala Val Gly Trp Ala Phe Gly Leu Ser Ser Trp Gly Ser Ser Cys Thr
          35                  40                  45            
 Gly Val Gly Leu Ala Leu Gly Ser Val Arg Ala Val Leu Lys His Arg
      50                  55                  60                
 Ser Ala Trp Ala Gly Pro Asn Pro Arg Ser Glu Gly Ala Asn Leu Thr
  65                  70                  75                  80
 Leu Glu Phe Thr Gly Ala Ser Ala Gly Val Tyr Phe Glu Asp Gln Val
                  85                  90                  95    
 Leu Thr Ser Leu Phe Ser Leu Ile Trp Lys Leu Ser Leu His Gly Met
             100                 105                 110        
 Gln Tyr Arg Leu Gly Lys Gly Val Ile Trp Leu Phe Leu Cys Asn Lys
         115                 120                 125            
 Pro Pro Pro Asn Leu Ser Gly Val Glu Gln Gln Gln Phe Arg Ile Ser
     130                 135                 140                
 His Val Ser Val Ser Glu Leu Gly Val Pro Ser Ala Ser Cys Ala Trp
 145                 150                 155                 160
 Ala His Ser His Gly Tyr Met Leu Val Gly Tyr Gln Leu Asp Trp Gln
                 165                 170                 175    
 Val Gln Gly Gly Ser Leu Met Tyr Gln Ala Ala Val Ala Gly Cys His
             180                 185                 190        
 Leu Ser Tyr Arg Lys Ala Ile Gly Asn Ser Ile Gln Asn Lys Glu Leu
         195                 200                 205            
 Lys Tyr Ile Glu Ala Ser Pro Thr Asn Phe Thr Thr Ile Ser Asn Lys
     210                 215                 220                
 Gly Glu Arg Glu Lys Glu Arg Asn Arg Glu Gly Arg Asp Ile Phe Cys
 225                 230                 235                 240
 Thr Tyr Ser Ser Leu Leu Leu Gln Arg Lys Pro Pro Met Val Val Asp
                 245                 250                 255    
 Asp Leu Phe Glu Asp Met Lys Asp Gly Val Lys Leu Leu Ala Leu Leu
             260                 265                 270        
 Glu Val Leu Ser Gly Gln Lys Leu Pro Cys Glu Gln Gly Arg Arg Met
         275                 280                 285            
 Lys Arg Ile His Ala Val Ala Asn Ile Gly Thr Ala Leu Lys Phe Leu
     290                 295                 300                
 Glu Gly Arg Lys Thr Leu Val Ile Lys Glu Leu Leu Phe Val Glu Ala
 305                 310                 315                 320
 His Val Thr Asn Met Leu Arg Thr Tyr Leu Gly Ala Leu Leu Asn Asp
                 325                 330                 335    
 Leu Ile Arg Phe Ser Gln Pro Leu Ala Phe Leu Tyr Thr Asn Asn Ile
             340                 345                 350        
 Trp Ala Glu Ser Glu Ile Asn Asn Thr Ile Pro Leu Thr Ile Ala Thr
         355                 360                 365            
 Lys Lys Met Lys Tyr Pro Gly Met His Leu Pro Lys Glu Val Lys Asp
     370                 375                 380                
 Leu
 385



      <210> 2002
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 2002
 Met Pro Thr Arg Val Ala Leu Trp Phe Phe Met His Met Gln Met His
   1               5                  10                  15    
 Met Ala Ile Pro Ala Met Thr Pro Met Ile Asn Thr Ile Pro Lys Thr
              20                  25                  30        
 Met Pro Ala Ile Ala Val Pro Leu Lys Gly Lys Thr Arg Cys Met Pro
          35                  40                  45            
 Ala Ser Leu Val Ser Ile His Gln Ile Pro Glu Val Ser Pro Leu Ala
      50                  55                  60                
 Val Ile Thr Lys Asp Ile Ser Arg Gly Trp Gly Ser Arg Pro Asn Cys
  65                  70                  75                  80
 Lys Asp Val Lys Glu Glu Val Ile Lys Met Arg Phe Glu Arg Ser Val
                  85                  90                  95    
 Ser Gln Gly Arg Arg Glu Lys Ser Ile Gln Gly Glu Glu Thr Thr Ser
             100                 105                 110        
 Arg Lys Ala Lys Glu His Arg Pro Val Leu Arg Glu Lys Ser Ser Ile
         115                 120                 125            
 Gln Gln Val Cys Ile Gln Phe
     130                 135



      <210> 2003
      <211> 393
      <212> PRT
      <213> Homo sapiens


      <400> 2003
 Met Ala Pro Leu Cys Thr Val Ala Leu Cys Leu Pro Val Gln Leu Pro
   1               5                  10                  15    
 Gln Thr Gly Pro Arg His Gln Val His Gly Val Pro Val Pro Trp Gly
              20                  25                  30        
 His Ser Arg Ser Thr Ala Gly Pro Glu Gly Leu Thr Val Gln Gln Glu
          35                  40                  45            
 Asp Arg Val Asn Glu Ile Lys Thr Ser Ala Pro Trp Cys Pro Gln Glu
      50                  55                  60                
 Val Ala His Pro Asp Ala His Ser Glu Pro Leu Pro Asp Val Ala Phe
  65                  70                  75                  80
 Gly Ala Cys Arg Gly Pro Trp Leu Val Asn Pro Gly Asn Gln Gly Ser
                  85                  90                  95    
 Ala Ser Arg Gly Ser Asp Phe Gly Ala Gly Asp Leu Gly Gln Val Thr
             100                 105                 110        
 Ser Pro Pro Val Lys Trp Ala Pro Gly Pro Gln Gly Pro Arg Gly Val
         115                 120                 125            
 Cys Leu Arg Gly Asn Gln Ala Gln Val Ile Ser Lys Arg Ile Arg Thr
     130                 135                 140                
 Arg Arg Val Ile Val Asp Arg Gly Ala Gly Leu Pro Arg Pro Thr Gln
 145                 150                 155                 160
 Leu Thr Pro Gly His Pro Ala Pro His Pro Ser Asp Pro Trp Thr Pro
                 165                 170                 175    
 Trp Arg Pro Leu Ala Gln Pro Pro Ala Ile Pro Glu Trp Trp Val Leu
             180                 185                 190        
 Pro Leu Gly Glu Trp Asn Gly His Leu Tyr Gln Ser Gln Pro Ser Leu
         195                 200                 205            
 Ala Val Cys Asp Thr His Thr Gln Lys Gly Arg Pro Pro Arg Glu Met
     210                 215                 220                
 Pro Ala Thr Leu Leu Ser Gly Arg Leu Gly Arg Leu Ala Leu Glu Leu
 225                 230                 235                 240
 Arg Leu Gly Ser Arg Thr Val Cys Leu Trp Val Pro Arg Gly Pro Ala
                 245                 250                 255    
 Leu Ala Leu Glu Asn Asp His Arg Arg Ala His Ser Ser Leu Lys Pro
             260                 265                 270        
 Ser His Arg His Pro Pro Gly Cys Val Pro Thr Pro His Ser Ala Leu
         275                 280                 285            
 Glu Ile Leu Leu Gln Gly Cys Pro Gly Pro Trp Asp Pro Ala Pro Ala
     290                 295                 300                
 Arg Pro Leu Pro Phe Thr Pro Gly Pro Gln Asp Cys His Pro Pro Leu
 305                 310                 315                 320
 Pro Leu Gly Pro Thr Leu Ala Gly Asp Glu Leu Glu Pro Val Val Gln
                 325                 330                 335    
 Asp Gly Gln Arg Arg Ile Arg Ala Arg Leu Ser Leu Ala Thr Gly Leu
             340                 345                 350        
 Ser Trp Gly Pro Phe His Gly Ser Val Gln Thr Arg Ala Ser Ser Pro
         355                 360                 365            
 Arg Gln Ala Glu Pro Gly Asn Met Asp Pro Gly Asp Arg Pro Ser Leu
     370                 375                 380                
 Asp Ala Ser Ser Gly Ala Leu Ala Thr
 385                 390            



      <210> 2004
      <211> 177
      <212> PRT
      <213> Homo sapiens


      <400> 2004
 Met Val Gly Pro Val Ser Arg Leu Val Leu Gly Pro Leu Phe Thr Ser
   1               5                  10                  15    
 Leu Cys Met Ala Leu Leu Cys Met Met Ser Leu Ala Gln Gly Ser Asn
              20                  25                  30        
 Ser Lys Met Gly Asn Gln Lys Gly His Ser Gly His Leu Ser Leu Ala
          35                  40                  45            
 Lys Thr Leu Gly Ser Asp Ser Thr Gly Val Leu Gly Ser Phe His Phe
      50                  55                  60                
 Cys Gly His Lys Lys Ala Lys Thr Ala Gln Ser Cys Asn Gln Val His
  65                  70                  75                  80
 Phe Met Tyr Leu Leu Leu Lys Pro Lys Ser Asn Val Leu Leu Ser Asp
                  85                  90                  95    
 Ile Arg Ser Lys His Ser Val Glu Glu Val Gln Gly Arg Glu Glu Glu
             100                 105                 110        
 Phe Arg Pro Gln Arg Arg Lys Ser Phe Gln Lys Ser Arg Glu Met Tyr
         115                 120                 125            
 Leu Ser Lys Gly Thr Ala Phe Ser His Asn Pro Gln Cys Cys Pro Gly
     130                 135                 140                
 Met Glu Lys Gly Cys Cys Leu Cys Phe Trp Leu Leu Ser Ser Gln Met
 145                 150                 155                 160
 Ala His Asp Lys Val Glu Val Lys Met Pro Lys Phe Phe Leu Thr Gln
                 165                 170                 175    
 Arg
    



      <210> 2005
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 2005
 Met Gly Phe Phe Ile Leu Cys Phe Gly Ile Leu Leu Asp Ser Lys Leu
   1               5                  10                  15    
 Arg Gln Leu Leu Phe Asn Lys Leu Ser Ala Leu Ser Ser Trp Lys Gln
              20                  25                  30        
 Thr Glu Lys Val Ile Ile Ser Tyr Cys His Glu Ser Asn Thr
          35                  40                  45    



      <210> 2006
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2006
 Met Gly His Asp Asn Leu Leu Thr Ser Val Ser Arg Gly Ile Thr Ile
   1               5                  10                  15    
 Leu Ser Leu Met Ala Leu Ala Gly Asp Ser Val Ala Gly Ile Gly Pro
              20                  25                  30        
 Gly Ala Lys Asn Gln Glu Pro Asp Gly Thr Ser Asn Met Tyr Ser Val
          35                  40                  45            
 Ile Gln Val Gly Lys Glu Lys Tyr Ala Thr Ser Val Ser Glu Glu Glu
      50                  55                  60                
 Ala Thr Phe Glu Val Leu Leu Leu Leu Tyr Leu Gly Phe Ala Glu Val
  65                  70                  75                  80
 Tyr Leu Gln Asp Leu His Pro Asp
                  85            



      <210> 2007
      <211> 306
      <212> PRT
      <213> Homo sapiens


      <400> 2007
 Met Ala Arg Gly Ser Val His Val Lys Leu Thr Val Ile Lys Leu Phe
   1               5                  10                  15    
 Val Leu Leu Ser Ile Ala Lys Gly Ala Glu Asp Gly Tyr His Leu Ala
              20                  25                  30        
 Arg Trp Val Ala Leu Leu His Ile Pro Ser Val His Phe Leu Arg Glu
          35                  40                  45            
 Asp Trp Cys Ile Val Ile Tyr Ile Cys His Ser Asp Arg Asp Gln Gly
      50                  55                  60                
 Arg Gly Gly Lys Arg Glu Cys Leu Ser Lys Gly Tyr Ser Gly Cys Tyr
  65                  70                  75                  80
 Phe Lys Val Glu Ser Trp Ala Gly Phe Thr Val Lys Ala Phe Val Lys
                  85                  90                  95    
 Leu Asn Ser Ala Cys Phe Leu Phe Tyr Asp Glu Tyr Ala Pro Phe Val
             100                 105                 110        
 Ile Phe Trp Pro Phe Pro Ile Asn Cys Ala Glu Pro Asp Ile Leu Thr
         115                 120                 125            
 Gly Gln Asn Pro Gln Gly Val His Cys Thr Pro Asn Gly Cys Ile Phe
     130                 135                 140                
 Cys Asn Ala Thr Tyr Val Leu Cys Glu Lys Ala Gly Leu Tyr Lys Leu
 145                 150                 155                 160
 Ala Pro Ser Thr Leu Ile Cys Thr Cys Ala Val Leu Val Asn Asn Pro
                 165                 170                 175    
 Ser Glu Thr Asp Thr Leu Arg Leu Tyr Arg Gly Ser Ile Arg Cys Phe
             180                 185                 190        
 Arg Trp Leu Asp Asn Val Ile Thr Pro Leu Leu Leu Ser Ile Arg Lys
         195                 200                 205            
 Leu Val Arg Ser Phe Pro Asp Lys Met Leu Tyr Ser Asn Arg Val Asn
     210                 215                 220                
 Phe Lys Val Ala Ile Val Ile Leu Gln Asp Ile Gly His Phe Ser Ile
 225                 230                 235                 240
 Trp Thr Phe Ile Phe Val Asn Gly Cys His Leu Ile Asn Gln Ser Pro
                 245                 250                 255    
 Gly Phe Arg Ile His Leu Asn Ser Ser Ile Val Trp Glu Ala His Lys
             260                 265                 270        
 Asp Trp Arg Ile Val Ile Tyr Val Phe Asn Val Asn Pro Asp His His
         275                 280                 285            
 Ser Gly His Thr Gln Met Val Gln Leu Thr Ala Gly Phe Tyr His Gln
     290                 295                 300                
 Leu Ile
 305    



      <210> 2008
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 2008
 Met Val Pro Ser Leu Val Leu Gln His Leu Met Cys Ala Gly Leu Trp
   1               5                  10                  15    
 Cys Leu Val Glu Gly Asp Thr Ser Cys Lys Thr Lys Leu Asp Pro Pro
              20                  25                  30        
 Leu Asp Gly Thr Glu Cys Gly Ala Asp Lys Trp Cys Arg Ala Gly Glu
          35                  40                  45            
 Cys Val Ser Lys Thr Pro Ile Pro Glu His Val Asp Gly Asp Trp Ser
      50                  55                  60                
 Pro Trp Gly Ala Trp Ser Met Cys Ser Arg Thr Cys Gly Thr Gly Ala
  65                  70                  75                  80
 Arg Phe Arg Gln Arg Lys Cys Asp Asn Pro Pro His Phe Lys Gln Asp
                  85                  90                  95    
 Pro Phe
        



      <210> 2009
      <211> 427
      <212> PRT
      <213> Homo sapiens


      <400> 2009
 Met Asn Ala Leu Ser Ile Leu Ile Pro Leu Asp Pro Leu Leu Ala Cys
   1               5                  10                  15    
 Pro Asn Pro Gln Pro Gln Thr Pro Leu Phe Leu Leu Leu His Leu Leu
              20                  25                  30        
 Leu Ile Gln Lys Leu Leu Gln Pro Val Lys Pro Pro Leu Pro Phe Ser
          35                  40                  45            
 Tyr Ser Gly Lys Trp Leu Gly Ser Lys Gln Phe Leu Gln Ala Val Ala
      50                  55                  60                
 Glu Gly Leu Gln Leu Leu Pro Val Arg Glu Pro Phe Ala Val Glu Lys
  65                  70                  75                  80
 Leu Gly Asp Glu Gly His Gly Gly Gly His Leu Ala Tyr Pro Gly Gly
                  85                  90                  95    
 Gly Ser Gly Val Glu Gly Met Gln Gly Gly Arg Gly Gly Ala Ala Arg
             100                 105                 110        
 Glu Arg Arg Gly Ser Ala Ala Leu Pro Gln Gln Leu Ser Ser Pro Gln
         115                 120                 125            
 Gly Phe Leu Thr Glu Gln Arg Ala Asp Arg Lys Lys Gly Ile Leu Pro
     130                 135                 140                
 Leu Lys Glu Ser Arg Ser Pro Gly Ala Cys His Ser Ala Asp Leu Ala
 145                 150                 155                 160
 Gly Gly Gln Val Ala Val Arg Ile Phe Leu Ala Leu Glu Gln Asp Ala
                 165                 170                 175    
 Val Gly Ser Asp Leu Leu Leu Arg Pro Pro Leu Ala Val Ser Thr His
             180                 185                 190        
 Ile Ala Gln Leu Asp Phe Gly Thr Ala Ala Gln Ser Leu Asp Pro His
         195                 200                 205            
 Gln Leu Gly Leu Asn Ala Gly Leu Arg Ser Cys Ser Thr Val Phe Gln
     210                 215                 220                
 Cys Gly Phe His Ala Glu Leu Arg Leu Gln Leu Asn Leu Lys Thr Pro
 225                 230                 235                 240
 Glu Gly Thr Pro Pro Val Arg Asp Ser Asp Leu Cys Ile Trp Ser Cys
                 245                 250                 255    
 Ser Val Trp Pro Ala Thr Ser Gln Leu Arg Ser Ser Val Trp Leu Val
             260                 265                 270        
 Thr Arg Leu Gln His Leu Gly His Leu Leu Ser Tyr Asp Arg Ile Leu
         275                 280                 285            
 Ala Ser Arg Val Ala Arg Asp Leu Gly Lys Thr Asn Ala Trp Ser Arg
     290                 295                 300                
 Ile His Leu His Thr Asp Leu Ala Thr Arg Ser Thr Asp Phe Leu Val
 305                 310                 315                 320
 Val Val Leu Leu Gln Val Ile Gln Leu Leu Leu Gln Ala Leu Asp Val
                 325                 330                 335    
 Arg Leu Gln Val Ser Pro Gly Arg Gly Arg Asn Gln Val Val Val Asp
             340                 345                 350        
 Val Leu Arg Gly Asp Leu Gly Ala Arg Gln Gln Pro Val Gly Pro Ala
         355                 360                 365            
 Glu Asp Ala Gly Ile Ala Ala Ala Ile Ala Pro Glu Glu Asp Glu Gly
     370                 375                 380                
 Thr Lys Trp Val Glu Asp Thr Asp Arg Leu Arg Leu Arg Ser Pro Ser
 385                 390                 395                 400
 Gly Cys Trp Ala Leu Gly Arg Arg Pro Arg Leu Gln Ser Ala Arg Ser
                 405                 410                 415    
 Arg Cys Pro Ala Pro Lys Gly Leu Ser Gly Gln
             420                 425        



      <210> 2010
      <211> 277
      <212> PRT
      <213> Homo sapiens


      <400> 2010
 Met Leu Ser Leu Tyr Phe Leu Ile Arg Gly Ser Pro Val Thr Val Thr
   1               5                  10                  15    
 Leu Tyr Val His Pro Gln Val Ser Gln Ser Pro Ser His Ser Thr Cys
              20                  25                  30        
 Ile Pro Arg Phe Pro Ser His Arg His Thr Leu His Ala Ser Gln Val
          35                  40                  45            
 Pro Pro Val Thr Val Thr Leu Tyr Met His Pro Gln Gly Ser Pro Val
      50                  55                  60                
 Thr Val Thr Leu Tyr Met His Pro Gln Val Ser Pro Val Thr Val Thr
  65                  70                  75                  80
 Leu Tyr Met His Pro Gln Val Pro Gln Ser Pro Ser His Ser Thr Cys
                  85                  90                  95    
 Ile Pro Arg Ser Pro Val Thr Val Thr Leu Tyr Val Pro Pro Gln Val
             100                 105                 110        
 Pro Pro Ser Pro His Thr Leu Arg Ala Ser Pro Gly Phe Pro Val Thr
         115                 120                 125            
 Val Thr Leu Tyr Met His Pro Gln Val Pro Pro Val Thr Ile Thr Leu
     130                 135                 140                
 Tyr Val His Pro Gln Val Ser Gln Ser Pro Ser His Ser Arg Cys Ile
 145                 150                 155                 160
 Pro Arg Phe Pro Arg His Arg His Thr Leu His Ala Ser Pro Gly Ser
                 165                 170                 175    
 Pro Val Thr Val Thr Leu Tyr Met His Pro Gln Val Pro Pro Val Thr
             180                 185                 190        
 Val Thr Leu Tyr Met His Pro Gln Val Tyr Gly Gly His Gly Thr Ala
         195                 200                 205            
 Leu Arg Ser Leu Val Ala Phe Thr Cys Ser Ser Leu Cys Cys Gln Tyr
     210                 215                 220                
 Gln Lys Leu Gln Asn Val Asn Tyr Gln Lys Arg Gln Glu Ala Ala Glu
 225                 230                 235                 240
 Gln Thr Arg Lys Glu Leu Ser Glu Lys Lys Pro Cys Ile Val Phe Gln
                 245                 250                 255    
 Ser Tyr Gly Arg Ser Glu Lys Gln Tyr Arg Trp Glu Thr Ser Trp Val
             260                 265                 270        
 Phe Trp Phe Leu Glu
         275        



      <210> 2011
      <211> 304
      <212> PRT
      <213> Homo sapiens


      <400> 2011
 Met Leu Pro Pro Pro Arg Pro Ala Ala Ala Leu Ala Leu Pro Val Leu
   1               5                  10                  15    
 Leu Leu Leu Leu Val Val Leu Thr Pro Pro Pro Thr Gly Ala Arg Pro
              20                  25                  30        
 Ser Pro Gly Pro Asp Tyr Leu Arg Arg Gly Trp Met Arg Leu Leu Ala
          35                  40                  45            
 Glu Gly Glu Gly Cys Ala Pro Cys Arg Pro Glu Glu Cys Ala Ala Pro
      50                  55                  60                
 Arg Gly Cys Leu Ala Gly Arg Val Arg Asp Ala Cys Gly Cys Cys Trp
  65                  70                  75                  80
 Glu Cys Ala Asn Leu Glu Gly Gln Leu Cys Asp Leu Asp Pro Ser Ala
                  85                  90                  95    
 His Phe Tyr Gly His Cys Gly Glu Gln Leu Glu Cys Arg Leu Asp Thr
             100                 105                 110        
 Gly Gly Asp Leu Ser Arg Gly Glu Val Pro Glu Pro Leu Cys Ala Cys
         115                 120                 125            
 Arg Ser Gln Ser Pro Leu Cys Gly Ser Asp Gly His Thr Tyr Ser Gln
     130                 135                 140                
 Ile Cys Arg Leu Gln Glu Ala Ala Arg Ala Arg Pro Asp Ala Asn Leu
 145                 150                 155                 160
 Thr Val Ala His Pro Gly Pro Cys Glu Ser Gly Pro Gln Ile Val Ser
                 165                 170                 175    
 His Pro Tyr Asp Thr Trp Asn Val Thr Gly Gln Asp Val Ile Phe Gly
             180                 185                 190        
 Cys Glu Val Phe Ala Tyr Pro Met Ala Ser Ile Glu Trp Arg Lys Asp
         195                 200                 205            
 Gly Leu Asp Ile Gln Leu Pro Gly Asp Asp Pro His Ile Ser Val Gln
     210                 215                 220                
 Phe Arg Gly Gly Pro Gln Arg Phe Glu Val Thr Gly Trp Leu Gln Ile
 225                 230                 235                 240
 Gln Ala Val Arg Pro Ser Asp Glu Gly Thr Tyr Arg Cys Leu Ala Arg
                 245                 250                 255    
 Asn Ala Leu Gly Gln Val Glu Ala Pro Ala Ser Leu Thr Val Leu Thr
             260                 265                 270        
 Pro Asp Gln Leu Asn Ser Thr Gly Ile Pro Gln Leu Arg Ser Leu Asn
         275                 280                 285            
 Leu Val Pro Glu Glu Glu Ala Glu Ser Glu Glu Asn Asp Asp Tyr Tyr
     290                 295                 300                





      <210> 2012
      <211> 252
      <212> PRT
      <213> Homo sapiens


      <400> 2012
 Met Pro Ser Leu Ile Leu Leu Phe Leu Leu Cys Ala Phe Ile Ala Gly
   1               5                  10                  15    
 Thr Leu Gln Glu Tyr Gln Lys Arg Met Lys Lys Leu Asp Gln Gln Tyr
              20                  25                  30        
 Lys Glu Arg Ile Arg Asn Ala Gly Cys Gly Pro Leu Gly Cys Phe Pro
          35                  40                  45            
 Pro Pro Ala Ala Cys Pro Pro Thr Leu Pro Gln Pro Val Gly Glu Leu
      50                  55                  60                
 Ser Ser Thr Glu Leu Val Pro Gly Ala Lys Lys Thr Glu Gln Val Glu
  65                  70                  75                  80
 Arg Asn Tyr Ile Lys Glu Lys Lys Ala Ala Val Lys Glu Phe Glu Asp
                  85                  90                  95    
 Lys Lys Val Glu Leu Lys Glu Asn Leu Ile Ala Glu Leu Glu Glu Lys
             100                 105                 110        
 Lys Lys Met Ile Glu Asn Glu Lys Leu Thr Met Glu Leu Thr Gly Asp
         115                 120                 125            
 Thr Glu Asp Ala Ser Glu Thr Asp Leu Ala Lys His Asp Glu Glu Asp
     130                 135                 140                
 Tyr Val Glu Met Lys Glu Gln Met Tyr Gln Asp Lys Leu Ala Ser Leu
 145                 150                 155                 160
 Lys Arg Gln Leu Gln Gln Leu Gln Glu Gly Cys Asp Phe Leu Lys Val
                 165                 170                 175    
 Ile Tyr Ser Phe Ile Leu Ser Leu Ala Ile Gln Tyr Ser Pro Trp Thr
             180                 185                 190        
 Ser Ser Asn Gly Ile Thr Trp Lys Leu Val Arg Asn Ala Gly Ser Leu
         195                 200                 205            
 Val Ser Asp Leu Leu Lys Leu Gly Ile Cys Ile Leu Thr Arg Cys Ser
     210                 215                 220                
 Ala Thr Val Thr Val Asp Ala Pro Val Arg Thr Gln Ala Met Gly Ala
 225                 230                 235                 240
 Glu Pro Arg Pro Pro Thr Val Asp Met Glu Cys Glu
                 245                 250        



      <210> 2013
      <211> 155
      <212> PRT
      <213> Homo sapiens


      <400> 2013
 Met Glu Ser Gly Glu Gly Phe Val Gly Asp Asn Cys Ala Ser Val Leu
   1               5                  10                  15    
 Leu Gly Cys Asn Trp Leu Leu Phe Trp Leu Gln Ala Ala Met Cys Ala
              20                  25                  30        
 Phe Gly Ala Gln Glu Ala Leu Gly Gln Pro Cys Asn Thr Ser Asp His
          35                  40                  45            
 Val Ala Leu Lys Gly Val Ala Gln Thr Leu Gly Ala Val Ala Ala Val
      50                  55                  60                
 Ala Val Leu Leu Gly Pro Gly Gly Gly Gln Gly His Val His Gly Cys
  65                  70                  75                  80
 Ser Ala Ser Ala Gly Gln Gly His Ile Thr Gly Leu Thr Gly Val Met
                  85                  90                  95    
 Glu Phe Arg Glu Asp Ser Ser Asn Pro Tyr Val Gln Phe Glu Ile Leu
             100                 105                 110        
 Gly Thr Thr Tyr Ser Glu Thr Phe Gly Lys Asp Met Arg Lys Val Ser
         115                 120                 125            
 Gly Pro Ser Thr Leu Pro Arg Gln Cys Ala Ser Lys Thr Leu Lys Pro
     130                 135                 140                
 Val Gly Ala Gly Ile Ser Gln Tyr Lys Lys Leu
 145                 150                 155



      <210> 2014
      <211> 174
      <212> PRT
      <213> Homo sapiens


      <400> 2014
 Met Val Leu Ile Trp Lys Thr Phe Phe Ile Phe Arg Ile Leu Ile Gln
   1               5                  10                  15    
 Val Leu Trp Gly His Cys Tyr Cys Gln Ser Cys Phe Glu Phe Gly Ser
              20                  25                  30        
 Thr Ser Pro Glu Pro Gln Val Arg Ile Phe Lys Leu Phe Ala Leu Trp
          35                  40                  45            
 Lys Asp Ala Asp Lys Ile Leu Ser Thr Thr Ile Val Ser Leu Leu Asp
      50                  55                  60                
 Gly Asn His Ile Phe Thr Ile Asp Ser Pro Pro Ile Gly Lys Val Ile
  65                  70                  75                  80
 Ala Thr Gln Cys Leu Glu Lys Leu Val Asp Pro Val Leu His Pro Arg
                  85                  90                  95    
 Ser Ala Ala Lys Glu Thr Arg Gly Pro Ser Lys Glu Ser Gly Glu Asn
             100                 105                 110        
 Gly Gln Arg Asn Ser Asp Ile Pro Tyr Leu Asn Glu Leu Phe Ser Leu
         115                 120                 125            
 Leu Val Leu Gly Pro Trp Pro Tyr Ala Cys Asn Thr Val Thr Cys Thr
     130                 135                 140                
 Trp Ile Gly Asn His Ile Ala Pro Gly Pro Ala Lys Ala Ile Lys Asp
 145                 150                 155                 160
 Arg Met Val Met Pro Arg Leu Thr Asp Val Arg Arg Leu Ser
                 165                 170                



      <210> 2015
      <211> 427
      <212> PRT
      <213> Homo sapiens


      <400> 2015
 Met Ser Leu Ala Ala Val Leu Pro Leu Leu Trp Gly Arg Trp Lys Val
   1               5                  10                  15    
 Glu Gly Ser Ser Trp Leu Pro Asn Leu Ile Pro Arg Gln Ser Pro Glu
              20                  25                  30        
 Thr Pro Ala Asp Leu Leu Pro Pro Arg Ala Ala Glu Pro Val Thr Gly
          35                  40                  45            
 Pro Leu Val Gly Ala Trp Val Gly Ser Val Leu Thr Ala Ser Asp Leu
      50                  55                  60                
 Ala Gly Ala Glu Cys Gly Asp Lys Arg Ala Leu Gly Met Gly Pro Pro
  65                  70                  75                  80
 Pro Pro Pro Gln Leu Gly Asp Arg Gly Glu Arg Pro Gly Cys Arg Gln
                  85                  90                  95    
 Ala Met Ser Gly Pro Trp Pro Ser Pro Asp Ser Arg Thr Lys Gly Thr
             100                 105                 110        
 Val Ala Trp Leu Ala Glu Val Leu Leu Trp Val Gly Gly Ser Val Val
         115                 120                 125            
 Leu Ser Ser Glu Trp Gln Leu Gly Pro Leu Gly Val Ala Val Pro Pro
     130                 135                 140                
 Leu Thr Ala Val Ser Leu Leu Arg Gly Val Ala Val Pro Pro Leu Thr
 145                 150                 155                 160
 Ala Val Ser Leu Pro Cys Pro Val Glu Arg Cys Met Gly Ala Met Gln
                 165                 170                 175    
 Glu Gly Met Gln Met Val Lys Leu Arg Gly Gly Ser Lys Gly Leu Val
             180                 185                 190        
 Arg Phe Tyr Tyr Leu Asp Glu His Arg Ser Cys Ile Arg Trp Arg Pro
         195                 200                 205            
 Ser Arg Lys Asn Glu Lys Ala Lys Ile Ser Ile Asp Ser Ile Gln Glu
     210                 215                 220                
 Val Ser Glu Gly Arg Gln Ser Glu Val Phe Gln Arg Tyr Pro Asp Gly
 225                 230                 235                 240
 Ser Phe Asp Pro Asn Cys Cys Phe Ser Ile Tyr His Gly Ser His Arg
                 245                 250                 255    
 Glu Ser Leu Asp Leu Val Ser Thr Ser Ser Glu Val Ala Arg Thr Trp
             260                 265                 270        
 Val Thr Gly Leu Arg Tyr Leu Met Ala Gly Ile Ser Asp Glu Asp Ser
         275                 280                 285            
 Leu Ala Arg Arg Gln Arg Thr Arg Asp Gln Tyr Pro Trp Ala Pro Ile
     290                 295                 300                
 Gly Gln Cys Arg Pro Arg Asp Arg Pro Leu Gly Cys Ser Pro Trp Gly
 305                 310                 315                 320
 Gly Leu Ser Phe Ala Gly Ser His Thr Gly Glu Val Ala Gly Gln Arg
                 325                 330                 335    
 Val Glu Trp Leu Lys Gln Thr Phe Asp Glu Ala Asp Lys Asn Gly Asp
             340                 345                 350        
 Gly Ser Leu Ser Ile Gly Glu Val Leu Gln Leu Leu His Lys Leu Asn
         355                 360                 365            
 Val Asn Leu Pro Arg Gln Arg Val Lys Gln Met Phe Arg Ala Pro Ala
     370                 375                 380                
 Pro Gln Pro Arg Gly Gly Tyr Thr Ser Pro Gly Arg Ala Gln Ser Asp
 385                 390                 395                 400
 Ala Gln Gln Leu Val Thr Phe Pro Met Pro Pro Ser Pro Asn His Pro
                 405                 410                 415    
 Asp Val Arg Ser Tyr Glu Asn Ala Ala Phe Ser
             420                 425        



      <210> 2016
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 2016
 Met Ala Asn Thr Thr Val Leu Lys Ala Trp Ile Leu Ser Leu Pro Tyr
   1               5                  10                  15    
 Ile Phe Arg Arg Leu Pro Val Cys Ala Leu Val Cys Pro Ser Val Arg
              20                  25                  30        
 Ile Pro Pro Ser His Gln Gln Cys Ser Val Pro Leu Pro Val Phe Cys
          35                  40                  45            
 Ala His Ser Pro Leu Pro Leu Cys Ala Pro Gly Arg Phe Ala Arg Thr
      50                  55                  60                
 Cys Phe Asn Thr Lys Arg Leu Gln Ser Pro Met Glu Pro Thr Lys Asp
  65                  70                  75                  80
 Val Phe Asn Phe Ser Lys Pro Ser Leu Glu Leu Lys Ala Gly Ala Leu
                  85                  90                  95    
 Glu Ala Tyr Val Gly Lys Thr Glu Val Asn Val Ile Pro Leu Lys His
             100                 105                 110        
 Lys Lys
        



      <210> 2017
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 2017
 Met Glu Cys Leu Pro Val His Met Trp Leu Asp Cys Leu Phe Gln Met
   1               5                  10                  15    
 Phe Gln Ile Leu Pro Leu Leu Leu Gly Ala Ser Leu His Cys Gly Leu
              20                  25                  30        
 Asn Pro Arg Gly Ile Asp His Pro Ala His Ala Glu Gly Ile Lys Leu
          35                  40                  45            
 Gln Ile Glu Gly Glu Gly Val Glu Ser Gln Ser Ile Lys Asn Lys Asn
      50                  55                  60                
 Phe Gln Lys Val Pro Asp Gln Lys Gly Thr Pro Lys Arg Leu Gln Ala
  65                  70                  75                  80
 Glu Ala Glu Thr Ala Lys Asp Ile Tyr Trp Leu Met Ile Asn Glu Val
                  85                  90                  95    
 Trp Phe Val Asn Asn Ile Gly Asn Glu
             100                 105



      <210> 2018
      <211> 438
      <212> PRT
      <213> Homo sapiens


      <400> 2018
 Met Ile Ala Val Glu Tyr Leu Leu Arg Ala Leu Leu Phe Ser Cys Gly
   1               5                  10                  15    
 Leu Cys Thr Leu Leu Ser Ser Thr Leu Ala Leu Glu Lys Lys Met Ala
              20                  25                  30        
 Gly Arg Gln Gly Arg Glu Glu Leu Ile Lys Lys Gly Leu Leu Glu Met
          35                  40                  45            
 Met Glu Gln Asp Ala Glu Ser Lys Thr Cys Asn Pro Asp Gly Gly Pro
      50                  55                  60                
 Arg Ser Val Gln Ser Glu Pro Pro Thr Pro Lys Ser Glu Thr Leu Thr
  65                  70                  75                  80
 Ser Glu Asp Ala Gln Pro Gly Ser Pro Leu Ala Thr Gly Thr Asp Gln
                  85                  90                  95    
 Val Ser Leu Asp Lys Pro Leu Ser Ser Ala Ala His Leu Asp Asp Ala
             100                 105                 110        
 Ala Pro Lys Gly Thr Ala His Ile Trp Ala Gln Ser Leu Cys Val Val
         115                 120                 125            
 Gly Asn Ser Met Thr Asp Arg Cys His Leu Met Ala Asp Lys Ala Arg
     130                 135                 140                
 Ser Ser Ser Gly Lys Cys Val Thr Trp Trp Leu Pro Leu Thr Thr Ala
 145                 150                 155                 160
 Trp Gly Leu Cys Trp Ser Gln Leu Pro Leu Gly Pro Gly Leu Trp Ala
                 165                 170                 175    
 Thr Ala Gly His Arg Val Glu Glu Pro His Leu Gly Val Ala Lys Met
             180                 185                 190        
 Pro Ser Ala Ser Ser Gly Glu Glu Ala Asp Ala Gly Ser Leu Leu Pro
         195                 200                 205            
 Thr Thr Asn Glu Leu Ser Gln Ala Leu Ala Gly Ala Asp Ser Leu Asp
     210                 215                 220                
 Ser Pro Pro Arg Pro Leu Glu Arg Ser Val Gly Gln Leu Pro Ser Pro
 225                 230                 235                 240
 Pro Leu Leu Pro Thr Pro Pro Pro Lys Ala Ser Ser Lys Thr Thr Lys
                 245                 250                 255    
 Asn Val Thr Gly Gln Ala Thr Leu Phe Gln Ala Ser Ser Met Lys Ser
             260                 265                 270        
 Ala Asp Pro Ser Leu Arg Gly Gln Leu Ser Thr Pro Thr Gly Ser Pro
         275                 280                 285            
 His Leu Thr Thr Val His Arg Pro Leu Pro Pro Ser Arg Val Ile Glu
     290                 295                 300                
 Glu Leu His Arg Ala Leu Ala Thr Lys His Arg Gln Asp Ser Phe Gln
 305                 310                 315                 320
 Gly Arg Glu Ser Lys Gly Ser Pro Lys Lys Arg Leu Asp Val Arg Leu
                 325                 330                 335    
 Ser Arg Thr Ser Ser Val Glu Arg Gly Lys Glu Arg Glu Glu Ala Trp
             340                 345                 350        
 Ser Phe Asp Gly Ala Leu Glu Asn Lys Arg Thr Ala Ala Lys Glu Ser
         355                 360                 365            
 Glu Glu Asn Lys Glu Asn Leu Ile Ile Asn Ser Glu Leu Lys Asp Asp
     370                 375                 380                
 Leu Leu Leu Tyr Gln Asp Glu Glu Ala Leu Asn Asp Ser Ile Ile Ser
 385                 390                 395                 400
 Gly His Asn Ala Phe Ile Gly Glu Glu Gly Asp Gly Asn Cys Phe Leu
                 405                 410                 415    
 Leu Thr Leu Thr Met Ser Ala Ala Arg Ala Pro Tyr Trp Val Phe Leu
             420                 425                 430        
 Val Ser Gly Met Leu Val
         435            



      <210> 2019
      <211> 307
      <212> PRT
      <213> Homo sapiens


      <400> 2019
 Met Gln Trp Val Leu Pro Ala Leu Leu Pro Pro Ser Phe Cys Ser Arg
   1               5                  10                  15    
 Met Leu Ala Val Gly Tyr Pro Asn Ser Thr Pro Gln Pro Tyr Ser His
              20                  25                  30        
 Ala Leu Gly Leu His Met Ser Lys Arg Val Phe Arg Leu Ala His Leu
          35                  40                  45            
 Pro Ser Ile Ile Lys Gly His Gly Asn Ala Thr Leu Ala Lys Cys Cys
      50                  55                  60                
 Cys Leu Asp Leu Gly Leu Pro Gly Leu Arg Asn Gly Ser Glu Asn Arg
  65                  70                  75                  80
 Trp Gly Ser Leu Tyr Ser Ser Ser His Pro Asn Thr Val Lys Gly Leu
                  85                  90                  95    
 Thr Pro Val His Leu Asp Thr Val Lys Gly Leu Thr Pro Val His Pro
             100                 105                 110        
 Asp Ala Val Lys Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly
         115                 120                 125            
 Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val Pro
     130                 135                 140                
 Pro Asp Ala Val Lys Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys
 145                 150                 155                 160
 Gly Leu Thr Pro Val Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val
                 165                 170                 175    
 Pro Pro Asp Ala Val Lys Gly Leu Thr Pro Val His Pro Asp Ala Val
             180                 185                 190        
 Lys Gly Leu Thr Pro Val Pro Pro Gly Gly Gln Leu Leu Tyr Val Arg
         195                 200                 205            
 His Ser Ala Arg Cys Arg Asn Arg Ala Glu Leu Val Ala Gly Ser Cys
     210                 215                 220                
 Gly Cys Ser Trp Arg Lys Gly Gly Leu Asn Ile Gly Trp Lys Lys Ser
 225                 230                 235                 240
 Tyr Glu Glu Pro Gly Lys Glu Pro Val Lys Phe Asn Cys Glu His Gln
                 245                 250                 255    
 Ser Leu Gly Arg Gln Arg Asp Lys Met Gly Gln Leu Ala Glu Glu Gln
             260                 265                 270        
 His Leu Cys Pro Trp Gln Cys Glu His Leu Ser Val Ser Ser Cys Leu
         275                 280                 285            
 Trp Trp Lys Pro Ala Gly Ser Leu Tyr Leu Leu Ala Val Gly Gly Asp
     290                 295                 300                
 Thr Gln His
 305        



      <210> 2020
      <211> 221
      <212> PRT
      <213> Homo sapiens


      <400> 2020
 Met Ala Ala Trp Val Gly Glu Gly Leu Leu Pro Leu Leu Gly Met Gly
   1               5                  10                  15    
 Met Leu Phe Leu Leu Ala Lys Lys Phe His Gln Ser Leu Gln Thr Gln
              20                  25                  30        
 Cys Pro His Leu Gln Lys His Pro Ser Thr Cys Ser His Ser Lys Leu
          35                  40                  45            
 Gln Asp Pro Ile Leu Phe Pro Ile Asn Ala Pro His Phe Asn Gly Lys
      50                  55                  60                
 His Leu Glu Arg Leu His Met Pro Phe Phe Gly Glu Val Asn Phe Leu
  65                  70                  75                  80
 Gly Val Gln Leu Cys Gly Ile Phe Gln Asp Ile Pro Ser Lys Val Lys
                  85                  90                  95    
 Asp Lys Leu Leu Asn Leu Thr Pro Pro Thr Thr Lys Lys Glu Ala Gln
             100                 105                 110        
 Cys Leu Val Gly Leu Phe Gly Phe Cys Arg Gln Asp Ile Pro His Met
         115                 120                 125            
 Gly Val Leu Leu Trp Pro Ile His Arg Val Thr Gln Lys Ala Ala Ser
     130                 135                 140                
 Phe Glu Trp Ala Pro Glu Gln Glu Lys Ala Leu Gln Gln Ile Lys Asp
 145                 150                 155                 160
 Ala Val Gln Ala Ala Leu Pro Leu Gly Pro Tyr Asp Pro Ala Asn Ser
                 165                 170                 175    
 Ile Val Leu Glu Val Thr Ala Ala Asp Lys Asp Ala Asp Gln Ser Leu
             180                 185                 190        
 Trp Gln Ala Pro Ile Gly Glu Leu Gln Gln Arg Pro Leu Lys Phe Trp
         195                 200                 205            
 Ser Arg Pro Cys His Leu Leu Lys Lys Leu Leu Ser Phe
     210                 215                 220    



      <210> 2021
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 2021
 Met Val Ile Thr Thr Ile Ile Ala Ile Ile Lys Leu Leu Ile Val Thr
   1               5                  10                  15    
 Gly Cys Pro Thr Phe Leu Arg Phe Ser Ser Ala Ile Cys Asp Ser Phe
              20                  25                  30        
 Leu Ile Cys Pro Gln Arg Gln Ser Gln His Gly Cys Asn Gln Gly Ile
          35                  40                  45            
 Leu Gly Ile Leu Pro Glu Ser Ile Pro Gln His Gln Ala His Asp Lys
      50                  55                  60                
 Val Ser Gly Ala Ser Met Ile Ser Lys Leu Ala Val Asp Leu Val Leu
  65                  70                  75                  80
 Glu Lys His Lys Asp Asn Leu Tyr Pro Lys Leu Leu Phe Tyr Pro Phe
                  85                  90                  95    
 Pro Asn Phe Leu Ser Leu Ala Leu Ser Thr Lys Pro Val Val Leu Leu
             100                 105                 110        
 Leu Ser Leu Gln Leu Val Ser Val Asp Ala Ile Gln Leu Leu Ile Ala
         115                 120                 125            
 Ser Gly Leu
     130    



      <210> 2022
      <211> 496
      <212> PRT
      <213> Homo sapiens


      <400> 2022
 Met Ala Ala Ala Trp Thr Val Val Leu Val Thr Leu Val Leu Gly Leu
   1               5                  10                  15    
 Ala Val Ala Gly Pro Val Pro Thr Ser Lys Pro Thr Thr Thr Gly Lys
              20                  25                  30        
 Gly Cys His Ile Gly Arg Phe Lys Ser Leu Ser Pro Gln Glu Leu Ala
          35                  40                  45            
 Ser Phe Lys Lys Ala Arg Asp Ala Leu Val Arg Glu Arg Pro Val Ala
      50                  55                  60                
 Leu Glu Ala Glu Leu Ala Leu Thr Leu Lys Val Leu Glu Ala Ala Ala
  65                  70                  75                  80
 Gly Pro Ala Leu Glu Asp Val Leu Asp Gln Pro Leu His Thr Leu His
                  85                  90                  95    
 His Ile Leu Ser Gln Leu Gln Ala Cys Ile Gln Pro Gln Pro Thr Ala
             100                 105                 110        
 Gly Pro Arg Pro Arg Gly Arg Leu His His Trp Leu His Arg Leu Gln
         115                 120                 125            
 Glu Ala Pro Lys Lys Arg Leu Val Val Val Leu Gly Arg Gln Gly Arg
     130                 135                 140                
 Gly Leu Cys Arg Ala Cys Ala Cys Ala Val Gly Leu Arg Ala His Val
 145                 150                 155                 160
 Ala Asp Pro Arg Glu Arg Pro Gly Ala Leu Asp Ala Ala Ala Val Pro
                 165                 170                 175    
 Val Ala Ile His Leu Ile Ala Asp His Glu Gln Asn Asp Glu Asp Glu
             180                 185                 190        
 Asp Arg Gly Asp Asp Asp Ala Pro Asp Gly Asp Asp His Gly Ala Ala
         195                 200                 205            
 Gln Glu Met Gly Pro Gln Arg Ala Ala Gly Arg Arg Ile Pro Ser Gly
     210                 215                 220                
 Gly Glu Leu Tyr Thr Ala His His Ser Arg Cys Arg Gln Arg Cys Gly
 225                 230                 235                 240
 Pro Val Val Val Asp Arg Gln His Ala Gln Val Val Gly Thr Ala Arg
                 245                 250                 255    
 Arg Gln Val Ile His Gln Glu Gly Leu Thr Asp Ile Lys Gly Asn His
             260                 265                 270        
 Leu Ile Cys Ser Cys Ala Thr Arg Ser His Gln Ile Thr Leu Pro Gly
         275                 280                 285            
 Leu Trp Ala Gly Gln Arg Met Ser Thr Glu Phe Glu Val Ser Ser Ala
     290                 295                 300                
 Ala Thr Ser Arg Arg Ser Ala Ala Glu Ser Leu Ala Pro Gly Leu Pro
 305                 310                 315                 320
 Gly Val Ala Met Ser Glu Glu Pro Gly Ser Glu Glu Pro Val Gly Arg
                 325                 330                 335    
 Glu Phe Met Gln Ala Val Gly Gly His Val Gln Thr Asp Gln Leu Val
             340                 345                 350        
 Lys Leu His Glu Gly Pro Leu Arg Asp Val Val Asp Glu Val Val Val
         355                 360                 365            
 Gln Arg Gln Ile Gln Val Leu His Gly Gly Gln Glu Gly Val Lys Gly
     370                 375                 380                
 Arg Arg Leu His Pro Ala Asp Leu Val Val Ser Lys Asp Gln Val Ala
 385                 390                 395                 400
 Glu Val Ala Gln Ala Ala Glu Leu Val Ala Ala His Leu Arg Gln Ala
                 405                 410                 415    
 Val Ala Val Gln Val Gln Gly Pro Glu Gly Thr Gln Val Gly Glu Gly
             420                 425                 430        
 Ala Ser Cys His Leu Ala Asp Gly Val Pro Gly Glu Ser Glu Val His
         435                 440                 445            
 Gln Ala Gly His Val Gly Glu Val Ser Ala Ala His Gly Gly Asp Glu
     450                 455                 460                
 Val Val Gly Ile Glu Gln Cys Pro Ile Ile Glu Ser Lys Tyr Phe Glu
 465                 470                 475                 480
 Ile Lys Gln Thr Gln Val Gln Ile Leu Ile Pro Leu Leu Leu Ala Leu
                 485                 490                 495    





      <210> 2023
      <211> 87
      <212> PRT
      <213> Homo sapiens


      <400> 2023
 Met Thr Ser Leu Met Met Leu Met Leu Thr Ile Cys Arg Tyr Ile Pro
   1               5                  10                  15    
 Asp Ala Gly Asp Trp Glu Val Asp Phe Phe Gly Glu Gly Ile Val Leu
              20                  25                  30        
 Pro Thr Met Val Pro Asn Gly Phe Ile Ser Met Asn Gln Ser Val Leu
          35                  40                  45            
 Val Glu Lys Met Cys Tyr Ser Leu Asp Ile Lys Leu Lys Lys Phe Ile
      50                  55                  60                
 Ser Phe Val Asn Phe Ser Lys Val Leu Met Asn Lys Val Ile Cys Ser
  65                  70                  75                  80
 Cys Phe Gln Phe Arg Thr Ile
                  85        



      <210> 2024
      <211> 180
      <212> PRT
      <213> Homo sapiens


      <400> 2024
 Met Lys Leu Gly Thr Arg Pro Leu Leu Asn Pro Leu Ser Arg Ala Ala
   1               5                  10                  15    
 Leu Leu Trp Pro Gln Gly Gln Ser Leu Val Leu Asn Pro Pro Trp His
              20                  25                  30        
 Pro Val Gly Leu Ser Arg Thr Leu Ser Pro Asp Ser Ala Ser Ser Leu
          35                  40                  45            
 Ser Pro Gly Cys Ala Pro Cys Ser Thr Leu Pro Leu Glu Cys Pro Ser
      50                  55                  60                
 Arg Glu Ala Phe Leu Arg Lys Pro Gly Ser Pro Glu Val Gln Pro Leu
  65                  70                  75                  80
 Arg Phe Leu Ala Pro Cys Pro Cys Ser Gly Pro Ala Val Leu Val Gln
                  85                  90                  95    
 Ala Trp Arg Lys Thr Asp Ala Arg Phe Gly Val Glu Gly Glu Leu Gly
             100                 105                 110        
 Gly Asp Glu Gly Pro Gly Arg Trp Lys Val Val Val Glu Asp Arg Gly
         115                 120                 125            
 Ala Gly Arg Trp Leu Gly Arg Gly Arg Val Lys Lys Pro Arg Ala Ala
     130                 135                 140                
 Leu Leu Ala Ala Ala Arg Gly Ala Thr Gly Cys Cys Pro Pro Pro Gln
 145                 150                 155                 160
 Pro Glu Ala His Phe Thr Arg Thr Glu Pro Lys Arg Glu Ser Leu Pro
                 165                 170                 175    
 Val Ser Arg Val
             180



      <210> 2025
      <211> 354
      <212> PRT
      <213> Homo sapiens


      <400> 2025
 Met Lys Ser Ser Ser Phe Thr Cys Leu Val Leu Asp Ala Gly Trp Leu
   1               5                  10                  15    
 Leu Gln Gly Ser Thr Gly Phe His Gly Asp Leu Ile Pro Ile Ile Ala
              20                  25                  30        
 Ala Leu Glu Tyr Asn Gln Trp Phe Thr Lys Leu Ser Ser Lys Asp Leu
          35                  40                  45            
 Lys Leu Ser Tyr Gly Ile Val Lys Glu Cys Phe Leu Leu Gln Ser Thr
      50                  55                  60                
 Asp Val Cys Glu Gln Ile Leu Arg Val Val Ser Arg Ser Asn Arg Leu
  65                  70                  75                  80
 Glu Glu Leu Val Leu Glu Asn Ala Gly Leu Arg Thr Lys Gln Ser Met
                  85                  90                  95    
 Leu Ile Ala Val Leu Gly Trp Val Ser Trp Cys Ser Gln Ser Pro Thr
             100                 105                 110        
 Leu Val Ile Lys Phe Arg Arg Tyr Leu Ile Leu Asn Thr Ile Asn Ser
         115                 120                 125            
 Trp Lys Gly Lys Glu Val Pro Pro Ser Phe Lys Gln Phe Phe Ser Ser
     130                 135                 140                
 Ser Leu Ala Leu Met His Ile Asn Leu Ser Gly Thr Lys Leu Ser Pro
 145                 150                 155                 160
 Glu Pro Leu Lys Ala Leu Leu Leu Gly Leu Ala Cys Asn His Asn Leu
                 165                 170                 175    
 Lys Gly Val Ser Leu Asp Leu Ser Asn Cys Glu Leu Arg Ser Gly Gly
             180                 185                 190        
 Ala Gln Val Leu Glu Gly Cys Ile Ala Glu Ile His Asn Ile Thr Ser
         195                 200                 205            
 Leu Asp Ile Ser Asp Asn Asp Thr Met Gln Asp Lys Gln Asn Leu Pro
     210                 215                 220                
 Leu Gly Cys Val Ala Phe Asn Ile Trp Phe Lys Trp Met Glu Asn Glu
 225                 230                 235                 240
 Trp Thr Gly Leu Asp Ser Pro Tyr Ser Leu Trp Ser Asn Lys Asn Val
                 245                 250                 255    
 Thr Gln Gly Leu Pro Leu Gln Ser Leu Ser Leu Ala Asp Ser Lys Leu
             260                 265                 270        
 Lys Thr Glu Val Thr Ile Ile Ile Asn Ala Leu Gly Ser Asn Thr Ser
         275                 280                 285            
 Leu Thr Lys Val Asp Ile Ser Gly Asn Gly Met Gly Asp Met Gly Ala
     290                 295                 300                
 Lys Met Leu Ala Lys Ala Leu Gln Ile Asn Thr Lys Leu Arg Asn Tyr
 305                 310                 315                 320
 Thr Leu Arg Phe Met Pro Ile Pro Met Tyr Asp Ala Ser Gln Ala Leu
                 325                 330                 335    
 Lys Thr Asn Pro Glu Lys Thr Glu Asp Ala Leu Gln Lys Val Leu Lys
             340                 345                 350        
 Asn Gln
        



      <210> 2026
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 2026
 Met Val Val Ala Thr Pro Lys Met Ala Ala Ser Leu Leu Phe Ser Asp
   1               5                  10                  15    
 Leu Gly Phe Leu Ala Ser Arg Ile Pro Lys Asn Gly Thr Leu Gly His
              20                  25                  30        
 Val Val Ser Val Ile Ala Leu Val Glu Val Met Gly His Gly Arg Glu
          35                  40                  45            
 Leu Trp Asn Pro Val Thr Ser Val Gln Leu Asp
      50                  55                



      <210> 2027
      <211> 221
      <212> PRT
      <213> Homo sapiens


      <400> 2027
 Met Asp Thr Ser Thr Cys Ser Gly Gly Ser Gly Arg Gly Val Lys Trp
   1               5                  10                  15    
 Thr Leu Arg Glu Ser Leu Val Leu Val Leu Phe Ser Ala Leu Val Phe
              20                  25                  30        
 Ser Asn Ala Gly Tyr Ala Ser Cys Glu Ala Val Thr Gln Thr Asp Ser
          35                  40                  45            
 Arg Pro Leu Val Ser Gln Gly Val Ala Gly Phe Ser Gly Ser Gln Trp
      50                  55                  60                
 Asp Val Gly Ala Glu Ala Asp Phe Ser Ser Ser His Thr Leu Gly Thr
  65                  70                  75                  80
 His Val Glu Phe Ala Ala Val Ser Cys Phe Phe Gln Arg Val Cys Glu
                  85                  90                  95    
 Phe Phe Gln Phe Ser Trp Tyr Val Pro Val Val Val Leu Gly Ala Lys
             100                 105                 110        
 Leu His Asn Leu Glu Glu Lys Gly Glu Glu Trp His Cys Leu Leu Lys
         115                 120                 125            
 Asp Asp Trp Leu Leu Leu Pro Ser Leu Val Gln Phe Met Asn Ser Leu
     130                 135                 140                
 Glu Phe Cys Asn Ala Val Ile Gln Val Ala His Pro Leu Ile Arg Asn
 145                 150                 155                 160
 Gln Leu Val Asn Tyr Ile Tyr Asn Gly Phe Leu Val Pro Val Leu Ala
                 165                 170                 175    
 Pro Ala Leu His Lys Trp Gln Leu Gly Thr Val Lys Met Phe Ser Lys
             180                 185                 190        
 Ala Glu Ser Val Ile Glu Asn Ala Arg Ser Ala Val Gly Met Glu Arg
         195                 200                 205            
 Ser Ser Gly Ser Thr Ser Ala Ile Asp Leu Pro Ser Thr
     210                 215                 220    



      <210> 2028
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 2028
 Met Ser Lys Val Ile Ile Phe Ser Tyr Leu Phe Trp Phe Val Leu Thr
   1               5                  10                  15    
 Ile Ile Phe Ile Thr Gly Thr Thr Arg Ile Ser Ile Phe Cys Met Gly
              20                  25                  30        
 Tyr Leu Val Ala Cys Phe Tyr Phe Leu Leu Phe Gly Gly Asp Leu Leu
          35                  40                  45            
 Leu Lys Pro Ile Lys Ser Ile Leu Arg Tyr Trp Asp Trp Leu Ile Ala
      50                  55                  60                
 Tyr Asn Val Phe Val Ile Thr Met Lys Asn Ile Leu Ser Ile Gly Ala
  65                  70                  75                  80
 Cys Gly Tyr Ile Gly Thr Leu Val His Asn Ser Cys Trp Leu Ile Gln
                  85                  90                  95    
 Ala Phe Ser Leu Ala Cys Thr Val Lys Gly Tyr Gln Met Arg Lys Tyr
             100                 105                 110        
 Glu Lys Gln Val Gly Ala Glu Leu Phe Gln Ala Thr Ile Val Lys Ala
         115                 120                 125            
 Val Lys Ala Arg Ile Glu Glu Glu Lys Lys Ser Met Asp Gln Leu Lys
     130                 135                 140                
 Arg Gln
 145    



      <210> 2029
      <211> 143
      <212> PRT
      <213> Homo sapiens


      <400> 2029
 Met Val Lys Phe Cys Trp Gln His Lys Phe Gly Leu Thr Trp Ser Leu
   1               5                  10                  15    
 Ile Ser Leu Asp Leu Ala Ala Ile Val Arg Leu Pro Ala Val Tyr Ile
              20                  25                  30        
 Leu Val Ala Ala Thr Ser Ala Leu Leu Cys Leu Val Val Pro Gly Leu
          35                  40                  45            
 Glu Asp Pro Arg Ala Arg Trp Gln Ala Phe Gly Leu Gly Lys Glu Leu
      50                  55                  60                
 Ala Gly Asp Leu Ala Val Leu Ala Val Pro Asp Pro Thr Leu Leu Ser
  65                  70                  75                  80
 Asn Gly His Arg Asp Gln Tyr Leu Ser Pro Pro Glu Thr His Ser Gly
                  85                  90                  95    
 Asn Leu Leu Glu Ser Ser Ala Leu Glu Ser Thr Leu Ile Pro Glu Val
             100                 105                 110        
 Ser Pro Pro Leu Phe Leu Pro Cys Asn Leu Ile Pro Pro Pro Leu Ala
         115                 120                 125            
 Phe Leu Ser Met Ala Ala Asp Pro Glu Asp Lys Gly Pro Ile Thr
     130                 135                 140            



      <210> 2030
      <211> 215
      <212> PRT
      <213> Homo sapiens


      <400> 2030
 Met Ile Ala Tyr Thr Leu Pro Thr Leu Ala Pro Phe Ser Leu Thr Arg
   1               5                  10                  15    
 Ala Tyr Thr Leu Thr Leu Gln Gln Leu Thr Leu Ser Met Ser Thr Val
              20                  25                  30        
 Val Gln Thr Ser Gly Thr Ser Ser Asp Thr Ser Ser Ile Ser His Ala
          35                  40                  45            
 Lys His Leu Val Arg His Ser Trp Ser Pro Ala Gly Val Pro Thr Ser
      50                  55                  60                
 Phe Gly Gly Lys Ser Pro Leu Val Phe Ile Glu Ala Gly Thr Glu Met
  65                  70                  75                  80
 Leu Met Asn Val Leu His Ser Leu Ser Pro Glu Ile Leu Thr Arg Gly
                  85                  90                  95    
 Met Gln Pro Thr Thr Trp Cys Arg His Gln Val Ala Leu Lys Leu Ser
             100                 105                 110        
 Ile Pro Glu Met Ser Ser Phe Cys Pro Leu Ile Arg Ala Asp Gln Met
         115                 120                 125            
 Leu Ala Gly Glu Thr Ser His His Leu Ser Pro Ala Phe Ser Leu Glu
     130                 135                 140                
 Asn His Pro Phe Leu Ile Gly Cys Cys Cys Phe Arg Gly Gln Ala Thr
 145                 150                 155                 160
 His Asn Ile Gln Ser Leu Thr Gly Thr Gly Arg Ile Ala Gln Thr Phe
                 165                 170                 175    
 Thr Val Pro Leu Leu Val Leu Gly Thr Glu Asp Ala Asn Met Ser Glu
             180                 185                 190        
 Pro Gln Phe Ala Ser Pro Val Pro Pro Ala Gln Gly Gly Thr Gly Asp
         195                 200                 205            
 Ala Asn Trp Arg Ser Asp Ile
     210                 215



      <210> 2031
      <211> 185
      <212> PRT
      <213> Homo sapiens


      <400> 2031
 Met Thr Phe Gln Gln Val Tyr Leu Gly Ile Met Thr Thr Cys Leu Asn
   1               5                  10                  15    
 Leu Gly Pro Thr Leu Glu Cys Lys Leu Glu Tyr Val Tyr Phe Met Val
              20                  25                  30        
 Val Glu Glu Ala Gln Glu Gly Lys Pro Lys Cys Val Gly Pro Leu Ser
          35                  40                  45            
 Lys Pro Ser Tyr Ile Ala Lys Ser Lys Val Lys Asp Leu Leu Ser Gln
      50                  55                  60                
 Asn Leu Glu Asn Thr Leu Asn Lys Val Phe Ala Gln Arg Lys Arg Ile
  65                  70                  75                  80
 Ser Thr Asp Arg Glu Cys Gln Thr Gln Leu Gln Ser Gln Pro Phe Ile
                  85                  90                  95    
 Lys Asn Lys Thr Arg Leu Phe Thr Leu Thr Ala Ser Val Gln His Cys
             100                 105                 110        
 Thr Arg Gly Gly Ser Gln Tyr Asn Lys Ala Asn Asn Glu Ile Glu Cys
         115                 120                 125            
 Ile Gln Val Glu Lys Lys Lys Val Lys Leu Thr Leu Ser Lys Asp Asp
     130                 135                 140                
 Met Ile Ile Ser Ala Glu Asn Leu Val Phe Tyr Gln Glu Lys Arg Lys
 145                 150                 155                 160
 His Met Ser Thr Gln Thr Leu Tyr Ile Asp Val His Asn Lys Leu Ile
                 165                 170                 175    
 Tyr Asp Asn Arg Lys Leu Glu Thr Thr
             180                 185



      <210> 2032
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2032
 Met Ala Phe Ile Phe Ser Phe Leu Met Val Val Leu Val Leu Tyr Val
   1               5                  10                  15    
 Ser Trp Lys Cys Phe Pro Ala Ser Leu Arg Gln Leu Arg Gln Cys Phe
              20                  25                  30        
 Val Thr Gln Arg Arg Lys Gln Lys Gln Lys Gln Thr Met His Gln Met
          35                  40                  45            
 Ala Ala Met Ser Ala Gln Glu Tyr Tyr Val Asp Tyr Lys Pro Asn His
      50                  55                  60                
 Ile Glu Gly Ala Leu Val Ile Ile Asn Glu Tyr Gly Ser Cys Thr Cys
  65                  70                  75                  80
 His Gln Gln Pro Ala Arg Glu Cys Glu Val Ser Arg Ser Ile Ile Glu
                  85                  90                  95    
 Ile Ser Val Ser Ile Glu Leu Lys Ser Glu Glu Val Val Val Val Ala
             100                 105                 110        
 Val Glu Gly Ala Asn Leu Ile Met Leu Cys Tyr Leu Lys Arg Thr
         115                 120                 125        



      <210> 2033
      <211> 76
      <212> PRT
      <213> Homo sapiens


      <400> 2033
 Met Thr Val Val Leu Glu Pro Leu Ala Leu Val Val Thr Val Thr Thr
   1               5                  10                  15    
 Ala Gly Arg Val Ala Val Val Val Thr Ala Leu Ala Phe Asp Gly Arg
              20                  25                  30        
 Val Glu Asn His Leu Gly Gly Ser Arg Leu Thr Tyr Cys Gly Gln Cys
          35                  40                  45            
 His Arg Arg Pro Gln Glu Gly Gly Pro Ala Gln Pro Met Asp Met Met
      50                  55                  60                
 Pro Lys Val Asp Gly Ile Ser Met Thr Gln Cys Gln
  65                  70                  75    



      <210> 2034
      <211> 462
      <212> PRT
      <213> Homo sapiens


      <400> 2034
 Met Gly Leu Pro Pro Cys Phe Lys Val Leu Ala Ala Thr Ala Leu Leu
   1               5                  10                  15    
 Ala Lys Asp Ala Asn Lys Leu Thr Phe Gly Gln Gln Leu Ile Ile Gln
              20                  25                  30        
 Val Pro His Thr Ile Val Thr Leu Met Glu Gln Arg Gly His Cys Trp
          35                  40                  45            
 Leu Ser Asn Arg Arg Met Leu Arg Tyr Gln Gly Leu Leu Cys Glu Asn
      50                  55                  60                
 Pro Tyr Ile Thr Leu Glu Ala Val Asn Thr Leu Asn Leu Ala Thr Leu
  65                  70                  75                  80
 Leu Pro Ile Glu Cys Ala Glu His Gly Lys Ser Leu Leu Cys Ala Pro
                  85                  90                  95    
 Gly Tyr His Cys Cys Val Glu Thr Val Asp Glu Val Phe Ser Ser Trp
             100                 105                 110        
 Glu Asp Leu Lys Asp Gln Pro Leu Arg Asn Pro Asp Val Glu Tyr Phe
         115                 120                 125            
 Thr Asp Gly Ser Ser Phe Ile Ser Glu Gly Ile Lys Lys Ala Arg Tyr
     130                 135                 140                
 Ala Val Val Thr Leu Ser Ser Val Ala Glu Ala Cys Pro Leu Pro Val
 145                 150                 155                 160
 Gly Thr Ser Ala Gln Lys Val Glu Leu Ile Ala Leu Thr Arg Ala Leu
                 165                 170                 175    
 Phe Leu Val Lys Gly Lys Ser Val Asn Ile Tyr Ala Asp Ser Lys Tyr
             180                 185                 190        
 Ala Phe Ala Thr Leu His Ala His Gly Ala Ile Tyr Asp Glu Arg Gly
         195                 200                 205            
 Leu Leu Thr Thr Glu Gly Lys Glu Ile Lys Asn Lys Lys Glu Ile Glu
     210                 215                 220                
 Gln Leu Leu Glu Ala Val Trp Ala Pro Lys Glu Val Ala Val Ile His
 225                 230                 235                 240
 Cys Lys Gly Gln Gln Thr Gly Arg Ser Asp Lys Ala Thr Gly Asn Ser
                 245                 250                 255    
 Lys Ala Asp Lys Glu Ala Arg Lys Thr Ala Met Thr Glu Lys Thr Lys
             260                 265                 270        
 Lys Glu Glu Thr Tyr Ala Met Pro Leu Leu Glu Pro Pro Leu Ala Asp
         275                 280                 285            
 Thr Pro Asn Tyr Ser Ser Asn Glu Lys Ala Ser Phe Val Gln Glu Asn
     290                 295                 300                
 Gly Ser Tyr Gln Lys Glu Gly Trp Trp Lys Phe Ser Asp Gly Arg Leu
 305                 310                 315                 320
 Thr Ile Pro Glu Ala Ile Ala Pro Gln Phe Ile Lys Gln Phe His Gln
                 325                 330                 335    
 Gly Thr His Met Gly Lys Thr Asp Leu Lys Ile Leu Ile Gly Tyr Tyr
             340                 345                 350        
 Thr Leu Asp Pro Ser Gln Leu Thr Glu Thr Cys Ser Leu Ser Ser Arg
         355                 360                 365            
 His Val Asp Glu Ser Ala Arg Ser Arg Ser Ser Asn Ser Thr Asp Leu
     370                 375                 380                
 Ala Glu Glu Pro Arg Arg Ser Arg Lys Arg Arg Pro Pro Cys Ser Asp
 385                 390                 395                 400
 His Thr Arg Ser Trp Ser Val Asn Ala Gln Leu Lys Leu Lys Glu Thr
                 405                 410                 415    
 Ser Ile Gln Ser Thr Met Glu Ala Ile Val Asp Arg Lys Thr Thr Thr
             420                 425                 430        
 Lys Ile Met Ala Leu Gln Lys Tyr Gln Pro Val Pro Gln Glu Glu Tyr
         435                 440                 445            
 Glu Pro Thr Gln Glu Glu Ile Asn Asp Cys Gly Ala Leu Tyr
     450                 455                 460        



      <210> 2035
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 2035
 Met Thr Phe Ser His Thr Leu Ser Phe Leu Thr Gly Cys Cys Gln Leu
   1               5                  10                  15    
 Ser Pro Phe Leu Ala Pro Gly Asn Trp Gly Glu Trp Lys Gly Glu Arg
              20                  25                  30        
 Lys Val Leu Lys Val Lys Ser Asp Pro Gln Glu Gln Glu Met Lys Thr
          35                  40                  45            
 Glu Ser Glu Val Asp Pro Lys Pro Ser Gly Leu Thr Thr Asn Pro Ile
      50                  55                  60                
 Ser Pro Ser Arg Ile Pro Cys Leu Ile Met Arg Tyr Leu Phe Ser Gln
  65                  70                  75                  80
 Ser Pro Ala Leu Ser Leu Glu Gly Ala Pro Arg Ser Thr Asp Tyr Gln
                  85                  90                  95    
 Pro Leu Lys Gly Thr His Gln Ser Leu
             100                 105



      <210> 2036
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 2036
 Met Glu Ile Asp Arg Glu Ala Lys Ala Val Leu Leu Val Leu Thr Leu
   1               5                  10                  15    
 Ile Leu Gln Leu Glu Ser Trp Pro Ile Leu Gly Val Val Ala Val Glu
              20                  25                  30        
 Ile His Gly Gly Leu Val Gly Arg Gly Glu Glu Gly Ala Trp Lys Leu
          35                  40                  45            
 Ala Ser Thr Glu Ser Ser His His Ala Ala Gly Leu Ile Gly Ala Ile
      50                  55                  60                
 Pro Asp Phe Tyr Val Val Val Val Gly Leu Gly Gly Glu Val Gln Glu
  65                  70                  75                  80
 Leu Asp Met Pro Met Pro Tyr Thr Val Val Lys Pro Gln Lys Arg Asn
                  85                  90                  95    
 Ala Ile Val Leu Glu Cys His Ser Leu Thr Ser Leu Pro Gln Asp Pro
             100                 105                 110        
 Asp Gly His Val His Asn Thr Val Leu Thr Gln Ser Asp Ile
         115                 120                 125    



      <210> 2037
      <211> 169
      <212> PRT
      <213> Homo sapiens


      <400> 2037
 Met Glu Gly Phe His Trp Phe Gly Gly Leu Trp Ser Trp Leu Leu Asn
   1               5                  10                  15    
 Arg Ile Gly Tyr Lys Asn Ala Lys His Cys Thr Ser Asn Ser Met Glu
              20                  25                  30        
 Asn Asn Asp Ser Pro Leu Cys Glu Leu Phe Arg Glu Leu Tyr Lys Ile
          35                  40                  45            
 Asn Glu Phe Asp Thr Pro Asp Ser Leu Leu Thr Lys Gly Lys Glu Phe
      50                  55                  60                
 Arg Lys Ser Ile Pro Asn Ile Phe Asp His Met Trp Arg Thr Lys Lys
  65                  70                  75                  80
 Arg Asn Glu Ala Cys Trp Leu Leu Leu Ser Ser Val Asn Lys Ile Met
                  85                  90                  95    
 Lys Glu Asn Asp Glu Leu Arg Asp Ser Ile Ser Gln Val Gln Lys Arg
             100                 105                 110        
 Ile Leu Ser Leu Lys Ser Ala Lys Ile Thr Leu Ser Glu Ser Leu Ile
         115                 120                 125            
 Ser Cys Ile Lys Arg Ala Glu Ile Val Glu Lys Gln Thr Gln Ala Leu
     130                 135                 140                
 Ile Met Gln Val Ala Asp Leu Gln Gln Lys Val His Ala Gln Pro His
 145                 150                 155                 160
 His Val Ser Thr Val Lys Arg Gly Tyr
                 165                



      <210> 2038
      <211> 164
      <212> PRT
      <213> Homo sapiens


      <400> 2038
 Met Ala Phe Ser Leu Met Thr Ala Leu Glu Gly Val Cys Ile Met Leu
   1               5                  10                  15    
 Met Arg Ile Pro Arg Ala Lys Glu Gly Leu Gly Phe Thr Val Asn Trp
              20                  25                  30        
 Ser Ser Leu Arg Ala Asp Ala Ala Ser Pro Ile Pro Ser Ile Gly Gln
          35                  40                  45            
 Trp Val Ser Tyr Leu Ser Glu Glu Cys Pro Lys Val Phe Leu Val Lys
      50                  55                  60                
 Ile Gly Leu Ala Gly Cys Cys Asp Ala Pro His Cys Pro Asp Gly Ala
  65                  70                  75                  80
 His Thr Ala Val Trp Arg Asn Arg Gly Val Gln Leu Ala Phe Thr Trp
                  85                  90                  95    
 Gln Arg Ser Val Met Ser Thr Arg Glu Ser Leu Pro Thr Ala Leu Val
             100                 105                 110        
 Leu Met His Leu Pro Ile Phe Phe Val Phe Glu Tyr Thr Arg Phe Pro
         115                 120                 125            
 Ala Leu Ile Leu Val Pro Gln Pro Gly Asp Val Val Gly Val Asp Leu
     130                 135                 140                
 Arg Lys His Glu Gly Ala Ile Val Ser Gln Val His Ile Thr Leu Ala
 145                 150                 155                 160
 Asp Gly Gly Asp
                



      <210> 2039
      <211> 248
      <212> PRT
      <213> Homo sapiens


      <400> 2039
 Met His Gly Leu Phe Leu Leu Leu Leu Pro Ala Leu Arg Asp Lys Ala
   1               5                  10                  15    
 Leu Ser Glu Leu Pro Glu Ala Gly Trp Glu Thr Leu Pro Gly His Val
              20                  25                  30        
 Glu His Gln Asp His Asp Glu Glu Gly Glu Asp Glu Gly His Gly Ala
          35                  40                  45            
 Arg Asp His Leu Val Asp Leu His Gly Val Leu Gly Val Leu Ala Ala
      50                  55                  60                
 Trp Lys Ser His Gly Gly Arg Leu Glu Cys Ala Val Val Leu Pro Leu
  65                  70                  75                  80
 Pro Ala Val Arg Glu Arg Gly Gly Arg Ala Gly Arg Gly Pro Gln Ile
                  85                  90                  95    
 Thr Ala Val Gly Asp Gly Arg Glu Gln Val Ala Ala Gly Gly Leu Gly
             100                 105                 110        
 Pro Ile Leu Ala Gln Val Glu Gly Val His Gly Val Gln Asp Val Leu
         115                 120                 125            
 Ala Leu Phe Gln Thr Gln Ser Ser Glu Leu Thr Thr Met Ala Thr Leu
     130                 135                 140                
 Phe Leu Arg Arg Gln Ser Glu Cys Arg Glu Met Arg Arg Gly Lys Trp
 145                 150                 155                 160
 Ala Lys Phe Thr Leu Thr Lys Ser Leu Cys Ser Arg Cys Ser Ser Gly
                 165                 170                 175    
 Glu Leu Lys Gln Ala Gly Glu Arg Val Ala Arg Gln Thr Leu Glu Leu
             180                 185                 190        
 Ile Val Ser Asp Val Glu Lys Leu Glu Ala Ala Ala Val Leu Glu Asp
         195                 200                 205            
 Ala His Gly His Lys Leu Asp Gly Val Gly Pro His Met Gln Arg Ala
     210                 215                 220                
 Ser Lys Leu Lys Arg Pro Thr Asn Gly Ile Lys Val Thr Lys Asp Trp
 225                 230                 235                 240
 Trp Tyr Phe Ser Gly Lys Val Ile
                 245            



      <210> 2040
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 2040
 Met Val Leu Val Tyr Pro Phe Cys Leu Gln Gln Leu Ala Leu Lys Leu
   1               5                  10                  15    
 Gln Lys Leu Leu Pro Gly His His Arg Thr Gly Leu Leu Leu Glu Gln
              20                  25                  30        
 Leu Gln Ile Pro Ser Met Arg Gly Arg Ala Arg Arg Arg Ser Gly Pro
          35                  40                  45            
 Gln Val Leu His Leu Lys Asp Lys Gly Lys Ala Leu Phe Ser
      50                  55                  60        



      <210> 2041
      <211> 53
      <212> PRT
      <213> Homo sapiens


      <400> 2041
 Met Ser Ile Cys Ile Leu Leu Ala Ile Cys Tyr Ser Phe Pro Ile Ala
   1               5                  10                  15    
 Phe Ser Val Tyr Ala Arg Ala Leu Gln Thr Ile Val Gly Lys Glu Lys
              20                  25                  30        
 Glu Ser Ser Ile Glu Gly His Lys Phe Met Leu Gly His Lys Gly Thr
          35                  40                  45            
 Thr Met Tyr Ser Thr
      50            



      <210> 2042
      <211> 162
      <212> PRT
      <213> Homo sapiens


      <400> 2042
 Met Ser Pro Cys Ser Ser Cys Trp Ala Leu Ile Leu Leu Glu Thr Leu
   1               5                  10                  15    
 Lys Ile Thr Asn Tyr Ala Gln Leu Thr Leu Tyr Ser Ser His Asn Phe
              20                  25                  30        
 Gln Asn Leu Phe Ser Ser Ser Tyr Leu Thr His Ile Leu Ser Ala Pro
          35                  40                  45            
 Trp Pro Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Pro Thr Val Thr
      50                  55                  60                
 Ile Val Pro Gly Leu Asp Phe Ser Leu Ala Ser His Ile Ile Pro Asp
  65                  70                  75                  80
 Thr Thr Thr Val Pro His Asp Cys Ile Ser Leu Ile His Leu Thr Phe
                  85                  90                  95    
 Thr Pro Phe Pro Arg Ile Ser Phe Phe Arg Val Pro His Pro Asp His
             100                 105                 110        
 Thr Trp Phe Ile Asp Gly Ser Ser Thr Arg Pro Asn Leu His Ser Pro
         115                 120                 125            
 Ala Lys Glu Gly Tyr Ala Arg Val Ser Ser Thr Ser Ile Ile Glu Ala
     130                 135                 140                
 Thr Thr Leu His Pro Ser Thr Thr Ser Gln Gln Ala Glu Leu Ile Ala
 145                 150                 155                 160
 Leu Thr
        



      <210> 2043
      <211> 326
      <212> PRT
      <213> Homo sapiens


      <400> 2043
 Met Pro Thr Phe Val Lys Gly His His Val Leu Leu Leu Ile Met Gly
   1               5                  10                  15    
 Met Cys Arg Ile Pro Glu Ala Glu Ala Arg Arg Glu Lys Glu Ile Ser
              20                  25                  30        
 Gly Ser Glu Phe Pro Pro Arg Gly Asn Ser Ile Ser Thr Pro Pro Asp
          35                  40                  45            
 Leu Gln Thr Leu His Thr Leu Ile Leu Pro Tyr Leu Arg Thr Cys Thr
      50                  55                  60                
 Arg Leu Pro Arg Phe Leu Glu Val Asn His Leu Phe Met Pro Gln Val
  65                  70                  75                  80
 Ala Asp Leu Phe Ile Asn His Gln Leu Leu Ser Leu Thr Gln Ser Val
                  85                  90                  95    
 Gly Pro Gly Met Phe Pro Pro Phe Gly Ser Tyr Asp Gly Glu Glu Leu
             100                 105                 110        
 Gly Asp Glu Gly Trp Asn Gln Thr Leu Cys Phe Phe Pro Arg Gly Leu
         115                 120                 125            
 Gly Asn Leu Asn Pro Lys Ser Gly Gln Phe Leu Thr Leu Phe His Met
     130                 135                 140                
 Glu Val Ser Phe Leu Phe Pro Glu Ser Lys Lys Thr Ala Val Ser Ile
 145                 150                 155                 160
 Leu Val Ser Asn Ala Val Ala Leu Val Ala Val Gln Pro Cys Ser Leu
                 165                 170                 175    
 Gln Ser Cys Arg Gln Leu Ala Ala Phe Ile Asp Leu Gly Ile His Ser
             180                 185                 190        
 Asp Asn His Gln Arg Gly Gln Gly His Tyr His Ser Ala Pro Gly Leu
         195                 200                 205            
 His Tyr Gly Thr Ser Pro Ala Ala Lys Gly His Gly Gly His Gly His
     210                 215                 220                
 Leu Ala Trp Ser Ser Asp Val Thr Gly Lys Ala Thr Phe Pro Leu Arg
 225                 230                 235                 240
 Leu Arg Cys Gly Pro Met Leu Thr Ile Gly Gly Arg Gly Leu Lys Gly
                 245                 250                 255    
 Ala Thr Glu Arg Ala Gln Asn Arg Pro Leu Gln Pro Phe Arg Leu Arg
             260                 265                 270        
 Cys Gln Arg Val Gly Pro Glu Ala Glu Val Leu Val Gly Ala Arg Leu
         275                 280                 285            
 Cys Asn Gly Leu Leu Ser Ser Glu Gln Lys Ile Cys Tyr Arg Glu Arg
     290                 295                 300                
 Met Ala Thr Phe Leu Leu Cys Pro Pro Met Ala Phe Pro Leu Leu Thr
 305                 310                 315                 320
 His Thr Glu Ser Lys Leu
                 325    



      <210> 2044
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 2044
 Met Gly His Ala Ala Thr Met Gly His Gln Ser Leu Cys Leu Val Val
   1               5                  10                  15    
 Leu Trp Ser Leu Leu His Ser Ser Ala Arg Ala Gly Ile Ser Leu Thr
              20                  25                  30        
 Asp Ser Ala Phe Ser Asp Ile Ala Thr Gln Ser Val Val Phe Lys Leu
          35                  40                  45            
 Leu Ser Pro Arg Lys Lys His Leu Lys Asn Pro Phe Val Gly Gly Gly
      50                  55                  60                
 Gly Cys Ala Trp Arg Thr Gly Trp Glu Trp Ser Pro Gly Gln Glu Gln
  65                  70                  75                  80
 Ala Pro Pro Pro Ala Thr Gly Ser Met Leu Ala Thr Ser Ser Pro Pro
                  85                  90                  95    
 Ser Gly Pro Pro Pro Pro Pro
             100            



      <210> 2045
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 2045
 Met Pro Gly Leu Cys Ile Phe Phe Met Phe Thr Leu Pro Arg Ala Asp
   1               5                  10                  15    
 Leu Ser Ile Leu Leu Ala Val Glu Asn Pro Ser Gln Val Val Pro Ile
              20                  25                  30        
 Ser Asn Val Met Gly Asn His Phe Ser Ser Lys Ala Ala Pro Pro Ser
          35                  40                  45            
 Glu Ser Leu Gln Gly Ala Leu Ser Ile Asp Ile Pro Glu Thr Lys Glu
      50                  55                  60                
 Pro Thr Asp Ser Gln Gly Gly Val Thr Val Asn Ser Lys Leu Gln Asn
  65                  70                  75                  80
 Ser Trp Cys Ile Leu Ile Ile Gln Lys Gln Leu Ala Arg
                  85                  90            



      <210> 2046
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 2046
 Met Gly Ser Ser Val Leu Ser Ile Trp Ile Leu Ser Pro Ser Ile Tyr
   1               5                  10                  15    
 Pro Ile Leu Ser Pro Leu Ala Met Pro Cys Leu Ser Arg Thr Asp Leu
              20                  25                  30        
 Ile Arg Val Val Lys Leu His Arg Asn Leu Pro Glu Glu Glu Val Asp
          35                  40                  45            
 Met Ala Ala Pro Leu His Arg Met Asp Lys Ala Ser Ala Ser Gly Leu
      50                  55                  60                
 Phe Leu Ala Pro Glu Ala Ser Val Asn Pro Pro Thr Pro Gln Ser Arg
  65                  70                  75                  80
 Ala Gly Ile Ala Lys Asn Pro Ala Arg Ser Asn Ser Ser Pro Lys Thr
                  85                  90                  95    
 Gln Val Arg Asn Arg Thr Ala Ala Ala Gln Ala Ala Asp Ala Pro Ala
             100                 105                 110        
 Lys Ser Ala Gln Leu Val Leu Arg Gly Ala Asn Arg Leu Glu Pro Arg
         115                 120                 125            
 Gly Trp Gly Ser Ala Gly Arg Met Val Leu Thr Leu Pro Arg Ser Leu
     130                 135                 140                
 Phe Phe Asp Pro
 145            



      <210> 2047
      <211> 106
      <212> PRT
      <213> Homo sapiens


      <400> 2047
 Met Val Ala Ser Leu Leu Phe Ser Asp Leu Gly Phe Leu Ala Ser Trp
   1               5                  10                  15    
 Ile Leu Arg Asn Gly Thr Leu Ser His Val Val Ser Val Ile Ala Leu
              20                  25                  30        
 Leu Glu Ala Val Gly His Gly Arg Glu Pro Trp Asn Pro Ala Thr Ser
          35                  40                  45            
 Val Gln Leu Asp Trp Asp Glu Pro Gly His Leu Ala Val Lys Glu Gln
      50                  55                  60                
 Trp Arg Ala Ser Ser Pro Ile Arg Ser Gly Asp Gly Arg Leu Ala Gly
  65                  70                  75                  80
 Ser Glu Thr Gln Cys Thr Pro Cys Arg Ile Gln Arg Gly Gly Ser Gln
                  85                  90                  95    
 Trp Trp Val Cys Asp Asn Gly Asn Gln Gln
             100                 105    



      <210> 2048
      <211> 257
      <212> PRT
      <213> Homo sapiens


      <400> 2048
 Met Val Val Lys Pro His Ala Ile Leu Ser Phe Thr Cys Leu Cys Met
   1               5                  10                  15    
 Thr Phe Ser Leu Glu Ala Leu Gly Val Arg Leu Phe Leu Val Ser Gly
              20                  25                  30        
 Thr Gly His Leu Asp Ala Gln Leu Gln Cys Asn Val Arg Asp Gly Phe
          35                  40                  45            
 Phe Thr His Arg Arg Asn Ser Thr Gln Gln Ile Gly Cys Ser Gln Glu
      50                  55                  60                
 Lys Gly Lys Asn Ala Leu Gly His Ser Pro Ser Thr Gln Pro Gln Ile
  65                  70                  75                  80
 Pro Ser Asp Asp Lys Thr Pro Ala Arg Val Tyr Thr Thr Pro Glu Ala
                  85                  90                  95    
 His Trp Thr Val Pro Pro Asn Pro Gly Ala Leu Gly Tyr Pro His Gln
             100                 105                 110        
 Ser Phe Val Ser Gln Pro His Pro Phe Arg Lys Gln Pro Ser Pro Cys
         115                 120                 125            
 Pro Arg Gln Ser Pro Gln Gly Asp Phe Gly Trp Val Thr Pro Gly Thr
     130                 135                 140                
 Ser Arg Ser Val Thr Gly Pro Ser Ser Pro Ala Ala Pro Ser Leu Ile
 145                 150                 155                 160
 Ser Leu Gly Ser Leu Gly Ser His Leu Gln Gly Ala Arg Pro His Pro
                 165                 170                 175    
 Arg Gln Ser Ser Leu Gly Asp Phe Gly Leu Val Thr Pro Gly Thr Pro
             180                 185                 190        
 Cys Cys Arg Leu Cys Pro Pro Leu Leu Leu Pro Gln Gly Arg Pro Pro
         195                 200                 205            
 Trp Val Leu Cys Ala Gly Val Ser Lys Glu Leu Gly Pro Asn Pro Val
     210                 215                 220                
 Leu Pro Ser Pro Ile Val Glu Arg Arg Leu Arg His Gly Ala Asp Thr
 225                 230                 235                 240
 Val Pro Pro Pro Asp Gln Glu Asp Trp Asn Val Val Met Ser Gln Pro
                 245                 250                 255    
 Thr
    



      <210> 2049
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 2049
 Met Leu Gln Pro Glu His Gly Val Arg Leu Gln Leu Leu Leu Leu Leu
   1               5                  10                  15    
 Met Leu Cys Asn Asp Gln Ser Ser Ala Gly Leu Trp Gly Pro Gln Arg
              20                  25                  30        
 Arg Leu Arg Ala Arg Ala Pro Arg Gln Phe Val Pro Phe Leu Asp Gly
          35                  40                  45            
 Gln Lys Leu Thr Cys Ser Val Cys Leu Pro Lys Asp Arg Gln Lys Gln
      50                  55                  60                
 Glu Asp Leu Gly His Asp
  65                  70



      <210> 2050
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 2050
 Met Leu Asp Leu Ser Lys Ser Phe Phe Gly Leu Leu Thr Leu Trp Ser
   1               5                  10                  15    
 Phe Gly Thr Phe Pro Ala Phe Gln Ser His Gly His Lys Ser Leu Ser
              20                  25                  30        
 Glu Val Ile Lys Asp Arg Gly Ser Lys Pro Asp Ala Pro Glu Met Trp
          35                  40                  45            
 Ala Lys Ala Ala Ala Asn Ala Ser Thr Ala Pro Phe Ser Ser Val Ser
      50                  55                  60                
 Ile
  65



      <210> 2051
      <211> 105
      <212> PRT
      <213> Homo sapiens


      <400> 2051
 Met Val Leu Val Cys Leu Phe Leu Pro Leu Pro Gln Asn Pro Gln Gln
   1               5                  10                  15    
 Ser Leu Asp Pro Ala Asp Gln Asn Ser Cys Thr His Arg Cys Ser Ser
              20                  25                  30        
 Arg Asn Thr Ser Cys Pro Arg Thr Leu Asp Pro Leu Ile Gly Ile Val
          35                  40                  45            
 Val Leu Thr Asp Ala Ala Ala Glu Thr Leu Val Phe Leu Leu Asp His
      50                  55                  60                
 Lys Glu Asp Gln Gly Met Leu Asp Leu Val Ala Leu Ala Asn Ala Phe
  65                  70                  75                  80
 Ser Lys Thr Cys Thr Leu Ala Cys Leu Pro Arg Thr Gln Arg Gly Pro
                  85                  90                  95    
 Arg Lys Ile Arg Phe Ser Gly Pro Tyr
             100                 105



      <210> 2052
      <211> 350
      <212> PRT
      <213> Homo sapiens


      <400> 2052
 Met Ala Val Val Ile Pro Ala Ala Leu Gly Thr Ala Ala Leu Val Pro
   1               5                  10                  15    
 Trp Ser Ile Leu Arg Gly Lys Ala Pro Arg Tyr Trp Leu Leu Pro Leu
              20                  25                  30        
 Leu Leu Asp Pro Asp Lys Val Pro Ile Ile Ser Ala Arg Asp Leu Thr
          35                  40                  45            
 Ser Pro Asp Ala Ala Leu Ala Ser Leu Thr Ala Gln Ser Gly Gly Leu
      50                  55                  60                
 Glu Glu Leu His Leu Lys Ala Ala Ser Phe Glu Trp Gly Pro Glu Gln
  65                  70                  75                  80
 Lys Lys Ala Leu His Gln Val Gln Ala Ala Met Pro Ala Ser Leu Pro
                  85                  90                  95    
 Leu Gly Pro Tyr Asp Pro Ala Asp Pro Met Val Leu Glu Val Ser Val
             100                 105                 110        
 Ala Glu Arg Asp Ala Val Trp Ser Leu Trp Gln Ala Pro Ile Gly Gly
         115                 120                 125            
 Pro Gln Gln Arg Pro Leu Gly Phe Leu Ser Lys Arg Gln Leu Leu Ala
     130                 135                 140                
 Cys Tyr Trp Ala Leu Val Glu Thr Glu Arg Leu Thr Met Gly His Gln
 145                 150                 155                 160
 Val Thr Ile Arg Pro Glu Leu Pro Val Met Asn Trp Val Leu Ser Asp
                 165                 170                 175    
 Ser Ser Ser His Lys Arg Phe Ile Leu Thr Gly Ile Asp Ile Tyr Ser
             180                 185                 190        
 Arg Tyr Gly Phe Ala Tyr Pro Ala His Asn Ala Ser Ala Lys Thr Thr
         195                 200                 205            
 Ile Arg Gly His Thr Glu Cys Val Ile His Arg His Gly Ile Pro His
     210                 215                 220                
 Ser Ile Ala Ser Asp Gln Gly Thr His Phe Met Ala Glu Glu Val Trp
 225                 230                 235                 240
 Gln Trp Ala His Ala His Gly Ile His Trp Ser Tyr Asp Ile Pro His
                 245                 250                 255    
 His Pro Glu Ala Ala Gly Leu Ile Glu Trp Trp Asn Gly Leu Leu Lys
             260                 265                 270        
 Ser Gln Leu Gln Cys Gln Leu Gly Asp Asn Thr Leu Gln Gly Trp Gly
         275                 280                 285            
 Lys Val Leu Gln Lys Ala Met Tyr Ala Leu Asn Gln His Gln Ile Tyr
     290                 295                 300                
 Gly Ile Val Ser Pro Ile Ala Arg Ile His Gly Ser Arg Asn Gln Glu
 305                 310                 315                 320
 Val Glu Val Asp Val Val Pro His Ala Ile Thr Pro Ser Asp Pro Leu
                 325                 330                 335    
 Ala Lys Phe Leu Leu Pro Val Pro His Tyr Ile Leu Val Ala
             340                 345                 350



      <210> 2053
      <211> 317
      <212> PRT
      <213> Homo sapiens


      <400> 2053
 Met Arg Leu Gly Leu Gln Gln Pro Leu Leu Leu Ala Leu Ser Leu Val
   1               5                  10                  15    
 Thr Asp Ala Lys His Phe Ser Gln Leu Leu Leu Arg His Gly Gly Glu
              20                  25                  30        
 Leu Val Ile Pro Leu Lys Ala Lys Gln Arg Leu Gly Thr Val Tyr Thr
          35                  40                  45            
 Phe Arg Ser Ala Ile Val Thr Ala Arg Ala Val Trp Val Arg Pro Arg
      50                  55                  60                
 Met Asp Arg Arg Ala Asp Leu Ser Ser Ala Thr Gln Ser Ala Ser Ala
  65                  70                  75                  80
 Glu Lys Phe Gly Gly Arg Val Ser Ala Gly His Cys Ala Leu Pro Leu
                  85                  90                  95    
 Pro Ala Arg Pro Val Thr Ala Ser Val Tyr Gly Arg Leu Ala Arg Leu
             100                 105                 110        
 Arg Gly Cys Leu Glu Asp Ser Tyr Pro Ser Ala Leu Ser Ala Gln Val
         115                 120                 125            
 Phe Leu Asp Ser Pro Ala Val Gly Cys Gly Leu Glu Thr Arg Leu Phe
     130                 135                 140                
 Ile Glu Ala Ala Leu Gly Pro Pro Cys Arg Ala Thr Val Thr Ser Arg
 145                 150                 155                 160
 Gly His Leu Leu Asp Ile Ser Ile Thr Lys Ser Pro Gly Arg Pro Cys
                 165                 170                 175    
 Phe Leu Ser Val Cys Leu His Gly Ser Asp Gln Gln Lys Arg Lys Gly
             180                 185                 190        
 Ala Ala Ala Thr Ala Lys Arg Lys Ser Lys Gly Gly Gly Val Asn Val
         195                 200                 205            
 Glu Gly Arg Leu Cys Thr Trp Pro Pro Glu Asp Pro Pro Lys Ser Trp
     210                 215                 220                
 Ser Leu Ala Phe Gly Pro Leu Gln Glu Lys Thr Thr Glu Leu Asn Leu
 225                 230                 235                 240
 His Pro Arg Cys Trp Ala Arg Cys Leu Ser His Trp Glu Leu Pro Pro
                 245                 250                 255    
 Gly Pro Arg Gly Arg Ala Gln Ala Pro Asp Trp Thr Gly Ser Lys Ser
             260                 265                 270        
 Phe Arg Glu Gln Leu Leu Thr Phe Thr Leu Trp Gly Val Gln Glu Lys
         275                 280                 285            
 Ile Ser Lys His Gln Ala Asn Gln Gly Lys Glu Ala Pro Ala Tyr Thr
     290                 295                 300                
 Gly Leu Glu Asp Ser Asp Pro Gly Gly Leu Cys Ala Val
 305                 310                 315        



      <210> 2054
      <211> 323
      <212> PRT
      <213> Homo sapiens


      <400> 2054
 Met Glu Gln Pro Ala Ile Leu Ile Ile Phe Met Pro Ile Phe Thr Ile
   1               5                  10                  15    
 Met Thr Met Ala Thr Pro Pro Leu Ser Asn Asp Gly Glu Leu Gly Ser
              20                  25                  30        
 Ile Glu Pro Lys Gln Pro Phe Ser Pro His Tyr Leu Gln Arg Gln Leu
          35                  40                  45            
 Phe Cys Phe Ser His Asn Ser Ala Gln Ala Pro Leu Cys His Ala Val
      50                  55                  60                
 Lys Gln Ser Lys Ser Glu Gly Ile Thr His Asn Val Glu Arg Pro Leu
  65                  70                  75                  80
 Ala Ala Thr Gly Ser Pro Pro Gly Thr Pro Met Gln Ala Asn Leu Leu
                  85                  90                  95    
 Gln Ser Ile Thr Met His Leu Pro Lys Ile Leu Gln Gly Leu Pro Gly
             100                 105                 110        
 Ser Trp Trp Leu Ala Val Lys Gln Gly Pro Gln Asn Gln Gln Gly Lys
         115                 120                 125            
 Leu Val Ala Asn Gly Asn Ser Leu Gly Ser Lys Glu Arg Lys Lys Ser
     130                 135                 140                
 Ser Val Lys Gly Tyr Gln Ala Ile Lys Trp Glu Ser Leu Val Glu Lys
 145                 150                 155                 160
 Asp Asp Phe Arg Thr Arg Cys Pro Val Ile His Leu Leu Gln Val Glu
                 165                 170                 175    
 Ser Phe Arg His Thr Asn Ala Ser Lys Thr Gly Ser Ser Glu Val Gly
             180                 185                 190        
 Arg Thr Arg Cys Leu Leu Gly Ile Val Leu Asp Val Gly Asp Gly Cys
         195                 200                 205            
 Val Asn Lys Arg Ala Val Val Pro Ala Ser Trp Arg Phe Val Thr Cys
     210                 215                 220                
 Gly Glu Ala Asp Asp Ser Ile Ser Thr Tyr Lys Ile Gln Arg Asp Lys
 225                 230                 235                 240
 Gly Glu Pro Pro Glu Pro Glu Ile Gln Val Pro Ala His Lys Gly Ser
                 245                 250                 255    
 Val Asn Thr Leu Met Cys Leu Phe Leu Leu Asp Lys Asp Asn Glu Ser
             260                 265                 270        
 Leu Cys Ser Ile Thr Val Asp Ala Leu Ile Ser Gln Ala Ser Leu Ser
         275                 280                 285            
 Ser Ala Ser Leu Glu Pro Thr Gly Arg Gln Ser Gln Phe Gln Lys Gly
     290                 295                 300                
 Glu Ser Gly Leu Val Pro Lys Glu Glu Gly Ile His Ala Glu His Ala
 305                 310                 315                 320
 Lys Ser Cys
            



      <210> 2055
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 2055
 Met Gly Arg Ala Trp Trp Leu Thr Pro Val Ile Pro Ala Leu Trp Glu
   1               5                  10                  15    
 Ala Lys Ala Gly Arg Thr Arg Gly Gly Ser Met Gln Ala Lys Glu Val
              20                  25                  30        
 Gly Ser Gly Val His Glu Cys Trp Asn Gln Leu Thr Asn Ser Val Pro
          35                  40                  45            
 Ala Gly Ser Asn Phe Thr His Ser Asp Leu Pro His Cys Thr Pro Cys
      50                  55                  60                
 Gly Arg Glu His Thr Gly Glu Trp Val Gln Glu Pro Gln Leu Ala Leu
  65                  70                  75                  80
 Leu Gly Thr Gly Ala Ser Glu Leu His Ala Gly Pro Ala Ala Ser Ser
                  85                  90                  95    
 Trp Glu Cys Met Arg Pro Leu Lys Pro Gln Arg Ala Val Ala Gln Ala
             100                 105                 110        
 Val Val Ser Glu Gly Ala Ser Leu Lys Pro Trp Gln Leu Pro Trp Gly
         115                 120                 125            
 Val Glu Pro Ala Ser Ala Lys Lys Ser Arg Ile Gly Val Trp Glu Pro
     130                 135                 140                
 Pro Pro Gly Phe Gln Arg Met Tyr Gly Asn Thr Trp Met Ser Arg Gln
 145                 150                 155                 160
 Lys Phe Ala Ala Gly Ala Gly Ile Ser Trp Gly Thr Ser Ser Arg Ala
                 165                 170                 175    
 Val Gln Glu Gly Asn Val Trp Leu Glu Pro Pro His Arg Val Pro Thr
             180                 185                 190        
 Gly Ala Thr Pro Ser Trp Ala Val Arg Arg Lys Pro Pro Ser Ser Arg
         195                 200                 205            
 Pro Gln Asn Asp Arg Ser Ile Asp His Leu Tyr Arg Ala Pro Gly Lys
     210                 215                 220                
 Ala Thr Asp Thr His Ala Cys His Asp Ser Ser Gln Glu Arg Gly Tyr
 225                 230                 235                 240
 Thr Leu Gln Ser His Arg Gly
                 245        



      <210> 2056
      <211> 154
      <212> PRT
      <213> Homo sapiens


      <400> 2056
 Met Leu Val Cys Cys Thr His Gln Pro Val Thr Tyr Ile Arg Tyr Ser
   1               5                  10                  15    
 Pro Asn Val Ile Pro Pro Leu Ala Pro His Thr Leu Gln Ala Leu Leu
              20                  25                  30        
 Phe Leu Val Phe Tyr Glu Leu Leu Asn Leu Phe Ala Leu Glu Gly Gly
          35                  40                  45            
 Ala Lys Ile Ala Glu Glu Glu Gln Leu Gln Ser Thr Ala Pro Ser Pro
      50                  55                  60                
 Leu Leu Leu Ile Pro Arg His Thr Gly Ser Gly Val Asp Phe Lys Gln
  65                  70                  75                  80
 Thr Pro Thr Asp Leu Gln Leu Arg Val Leu Asn Val Arg Arg Lys Thr
                  85                  90                  95    
 Asn Lys Gln Lys Gly His Pro His Gln Lys Pro Leu Cys Thr Ser Pro
             100                 105                 110        
 Ser Ser Lys Thr Lys Gly Met Gln Leu Leu Thr Thr Thr Glu Gln Ser
         115                 120                 125            
 Trp Thr Glu Asn Asp Phe Asp Lys Leu Thr Lys Asp Gly Phe Arg Arg
     130                 135                 140                
 Ser Asn Lys Ser Glu Leu Lys Glu Glu Val
 145                 150                



      <210> 2057
      <211> 268
      <212> PRT
      <213> Homo sapiens


      <400> 2057
 Met Lys Pro Arg Ala Arg Gly Trp Arg Gly Leu Ala Ala Leu Trp Met
   1               5                  10                  15    
 Leu Leu Ala Gln Val Ala Glu Gln Val Ser Pro Gly Arg Ser His Gln
              20                  25                  30        
 Arg Gly Asn Arg Gly Ser Gly Gln Leu Glu Ala Ser Pro Pro Arg Leu
          35                  40                  45            
 Leu Ser Arg Gly Pro Arg Arg Leu Thr Ala Met Ser Pro Leu Phe Ser
      50                  55                  60                
 Ala Gly Thr Cys Val Arg His Gly Thr Arg Ser Gly Ser Ala Trp Glu
  65                  70                  75                  80
 Pro Glu Arg Pro Ala Ser Ser Ser Thr Arg Gly Ala Ala Gly Leu Asp
                  85                  90                  95    
 Gly Lys Gly Arg Asp Met Asp Glu Ala Gly Asn His Arg Ser Gln Gln
             100                 105                 110        
 Thr Asn Thr Gly Thr Glu Asn Gln Thr Leu His Val Leu Thr Gln Tyr
         115                 120                 125            
 Asp Leu Val Ser Ala Tyr Glu Val Asp His Arg Gly Asp Tyr Val Ser
     130                 135                 140                
 His Glu Ile Met His His Gln Arg Arg Arg Arg Ala Val Ala Val Ser
 145                 150                 155                 160
 Glu Val Glu Ser Leu His Leu Arg Leu Lys Gly Pro Arg His Asp Phe
                 165                 170                 175    
 His Met Asp Leu Arg Thr Ser Ser Ser Leu Val Ala Pro Gly Phe Ile
             180                 185                 190        
 Val Gln Thr Leu Gly Lys Thr Gly Thr Lys Ser Val Gln Thr Leu Pro
         195                 200                 205            
 Pro Glu Asp Phe Cys Phe Tyr Gln Gly Ser Leu Arg Ser His Arg Asn
     210                 215                 220                
 Ser Leu Ser Gly Pro Phe Asn Leu Pro Arg Leu Gly Glu Tyr Ser Ala
 225                 230                 235                 240
 Ser Pro Arg Ile Ile Val Asp Glu His Phe Ser Leu Lys Leu Val Tyr
                 245                 250                 255    
 Lys Asn Arg Trp Pro Asn Leu Asn Ser Leu Ala Ser
             260                 265            



      <210> 2058
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 2058
 Met Pro Arg Val Arg Lys Leu Lys Tyr Leu Leu Val Trp Val Asp Thr
   1               5                  10                  15    
 Phe Thr Gly Trp Val Glu Ala Phe Pro Thr Gly Ser Glu Lys Ser Thr
              20                  25                  30        
 Ala Ile Ile Ser Ser Leu Leu Ser Asp Ile Ile Pro Trp Phe Gly Leu
          35                  40                  45            
 Pro Thr Ser Ile Gln Ser Asn Asn Arg Pro Ala Phe Ile Ser Gln Ile
      50                  55                  60                
 Thr Gln Ala Val Ser Gln Ala Leu Gly Ile Gln Trp Asn Arg His Asn
  65                  70                  75                  80
 Pro Tyr Arg Ser Gln Ser Ser Gly Lys Val Lys Trp Thr Ile Gly Leu
                  85                  90                  95    
 Leu Lys Thr His Leu Thr Lys Leu Ser Leu Gln Leu Lys Lys Asp Trp
             100                 105                 110        
 Thr Ile Leu Leu Pro Leu Ala Leu Leu Arg Ile Gln Ala Cys Pro Gln
         115                 120                 125            
 Asp Ala Thr Gly Tyr Ser Pro Phe Glu Leu Leu Tyr Gly Arg Ser Ile
     130                 135                 140                
 Leu Leu Gly Pro Ser Ile Ile Pro Asp Thr Ser Pro Thr
 145                 150                 155        



      <210> 2059
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 2059
 Met Leu Val Thr Leu Gln Leu Leu Lys Ala Gln Met Leu Thr Ala Ala
   1               5                  10                  15    
 Ser Gly Gly Leu Trp Glu Pro Val Asn Ala Asn Ile Pro Ile Ala Cys
              20                  25                  30        
 Ser Gly Cys Ser His Pro Gly Phe Leu Val Gly Leu Phe His Glu Leu
          35                  40                  45            
 Gly Asn Leu Leu Ser Asp Ser Lys Ala Tyr
      50                  55            



      <210> 2060
      <211> 207
      <212> PRT
      <213> Homo sapiens


      <400> 2060
 Met Val His Tyr Phe Leu Arg Val Ser Tyr Val Ala Leu Thr Leu Gly
   1               5                  10                  15    
 Ser Leu Ala Gly Arg Gly Arg Gln Lys Gln Ser Ser Val Ala Asn Gly
              20                  25                  30        
 Thr Cys Ser Lys Ala Thr Pro Arg Pro Ser Phe Thr Leu Arg Thr Glu
          35                  40                  45            
 His Cys Met Ser Ser Ser Trp Leu Pro Val Phe Tyr Thr Phe Arg Gly
      50                  55                  60                
 Thr Ser Leu Gly Ile Ser Lys Arg Lys Ala Ala Ala Pro Val Arg Ala
  65                  70                  75                  80
 Leu Glu Ile Lys His Pro Ser Pro Trp Asn Arg Ala Pro Trp Gly Arg
                  85                  90                  95    
 Gly Asn Cys Gly Tyr Arg Phe Ser Arg Leu Glu Val Ser Cys Leu Pro
             100                 105                 110        
 Ala Val Lys Lys Ala Ala Asp Ile Pro Ala Glu His Ser Ser Ser Ala
         115                 120                 125            
 Lys Gly Gln Ile Ala Ser Ser Arg Asp Thr Ser Gln Thr Gly Val Asp
     130                 135                 140                
 Arg His Leu Ile Gln Glu Ser Ser Asn Trp His Leu Ala Ser Ala Pro
 145                 150                 155                 160
 Leu Glu Arg Ser Cys Gln Arg Lys Glu Gln Ala Ala Ile Phe Ala Ile
                 165                 170                 175    
 Leu Gln Pro Leu Leu Val Ile Ser Arg Gln Thr Gly Ser Gly Val Asp
             180                 185                 190        
 Leu Gln Gln Ile Pro Thr Asp Ala Ala Ala Glu Gly Pro Asp Cys
         195                 200                 205        



      <210> 2061
      <211> 60
      <212> PRT
      <213> Homo sapiens


      <400> 2061
 Met Gly Leu Pro Arg His Leu Leu Gln Ala Cys Thr Leu Ala Gly Pro
   1               5                  10                  15    
 Trp Leu Leu Glu Ala Ser Pro His Gln Cys Ala Leu Cys His Tyr Phe
              20                  25                  30        
 Leu Cys Leu Cys Gly Phe Val Leu Ser Gly Trp Ala Lys Ile Ser Ser
          35                  40                  45            
 Phe Glu Asp Gly Ser Val Gly Ile Ser Gly Pro Leu
      50                  55                  60



      <210> 2062
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 2062
 Met Pro Ala Thr Trp Pro Cys Val Arg Ser Arg Ser Cys Ala Cys Ala
   1               5                  10                  15    
 Leu Ser Leu Ala Leu Ala Leu Ser Leu Met Leu Ile Leu Gln Ala Phe
              20                  25                  30        
 Tyr Arg Pro Pro Met Ser Gln Glu Pro Ala Leu Ser Thr Val Leu Phe
          35                  40                  45            
 Leu Leu Leu Leu Leu Ala Asn Pro Pro Thr Lys Val Ser Arg Ser His
      50                  55                  60                
 Arg Glu Glu Arg Val Leu Leu Leu Val Ala Leu Pro Leu Gly Cys Asp
  65                  70                  75                  80
 Thr Leu Ala Glu Leu Arg Leu His Arg Leu
                  85                  90



      <210> 2063
      <211> 226
      <212> PRT
      <213> Homo sapiens


      <400> 2063
 Met Leu Val Ala Val Trp Glu Ala Leu Leu Gly Leu His Val Pro Trp
   1               5                  10                  15    
 Ser Gln Gln Gly Leu Glu Ala Gly Arg Ser Pro Thr Leu Leu Gly Thr
              20                  25                  30        
 Ala Ala Ala Thr Gln Val Ala Ala Ala Asp Leu Gly Ile Ser Ala Leu
          35                  40                  45            
 Ser Gly Ala Trp Glu Gly Ser Arg Ala Pro Ala Gly Ser Gly Cys Leu
      50                  55                  60                
 Leu Pro Met Ser Gly Leu Ser Leu Leu Leu Val Pro Ala Leu Ile Ser
  65                  70                  75                  80
 Glu Gln Gly Leu Asp Asn Ile Leu Leu Ser Leu Glu Lys Leu Arg Asn
                  85                  90                  95    
 Pro Pro Leu Cys His Leu Leu Glu Pro Leu Ser Thr Leu Cys Asn Ser
             100                 105                 110        
 Lys Arg Gln Val Thr Pro Thr Phe Gln Lys Thr Phe Arg Ser Lys His
         115                 120                 125            
 Gln Pro Phe Pro Arg Gly Gln Ala Ala Glu Arg Ala Phe His Cys Ser
     130                 135                 140                
 Lys His Leu Leu Asn Asn Tyr Phe Leu Gln Val Thr Gly Gln Val Thr
 145                 150                 155                 160
 Trp Met Gln Leu Ala Ala Ile Ile Leu Ser Lys Leu Met Gln Glu Gln
                 165                 170                 175    
 Lys Thr Lys Tyr Gln Met Phe Ser Leu Tyr Lys Trp Glu Leu Asn Asp
             180                 185                 190        
 Glu Asn Lys Gln Thr His Arg Gly Glu Gln Gln Thr Gln Val Pro Thr
         195                 200                 205            
 Gly Glu Trp Arg Val Glu Lys Gly Arg Gly Ser Gly Lys Ile Ile Asn
     210                 215                 220                
 Glu Tyr
 225    



      <210> 2064
      <211> 265
      <212> PRT
      <213> Homo sapiens


      <400> 2064
 Met Leu Thr Pro Gly Leu Thr Pro Leu Leu Gly Gly Leu Ser Arg Ala
   1               5                  10                  15    
 Leu Gly Ala Gln Gly Leu Pro Pro Leu Ala Asn Phe Leu Leu Gly Asn
              20                  25                  30        
 Arg Gly Leu Asp Ala His Ile Asn Leu Ser Leu His Leu Arg Ser Glu
          35                  40                  45            
 Glu Ala Pro Leu Glu Glu Thr Glu Ala Ala Ala Thr His Glu Ser Arg
      50                  55                  60                
 Ser Gly Gly Tyr Gly Ser Glu Pro Ala Arg Glu Arg Ala Ser Ser Gln
  65                  70                  75                  80
 Gly Arg Lys Gly Asp Ser Ser Glu Gly Arg Arg Glu Glu Gly Arg Lys
                  85                  90                  95    
 Gly Pro Lys Thr Ser Pro Pro Arg Gly Ser Cys His Pro Ala Arg Glu
             100                 105                 110        
 His Arg Ser Val Thr Arg Asp Ala Ala Glu Val Arg Gln Glu Pro Pro
         115                 120                 125            
 Lys Gly Leu Ser Trp Gly Asp Ser His Arg Cys Pro Glu Gly Pro Arg
     130                 135                 140                
 Thr Glu Ser Thr Leu Ala Pro Ala Gly Leu His Met Leu Arg Glu Leu
 145                 150                 155                 160
 Asp Arg Gly Lys Ala Val Ala Val Gly Arg Gly Arg Arg Asp Ala Arg
                 165                 170                 175    
 Leu Ala Gly Arg Ala Gly Leu Arg Ser Gly Ala Ala Ala Ala Leu Pro
             180                 185                 190        
 Gly Lys Ala Ala Leu Ala Ala Gly Leu Ser Ala Gly Glu Asp Arg Leu
         195                 200                 205            
 Leu Pro Ala Leu Leu Arg Arg Ala Leu Thr Ala Gly Ala Ala Pro Ala
     210                 215                 220                
 Arg Pro Leu Val His Gly Pro Pro Gly Thr Glu Leu Arg Cys Ser Pro
 225                 230                 235                 240
 Pro Pro His Gly Ser Leu Asn Thr Phe Pro Leu Leu Val Thr Ala Val
                 245                 250                 255    
 Ile Leu Glu Ala Phe Met Pro Thr Leu
             260                 265



      <210> 2065
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 2065
 Met Arg Asp Gln Gln Ser Lys Leu Lys Leu Leu Leu Leu Cys Val Phe
   1               5                  10                  15    
 Ser Met Cys Ile Lys Arg Cys Ser Ile Gln Cys Leu His Glu Ser Cys
              20                  25                  30        
 Leu Lys Ile Met Cys Pro Val Thr Ile Met Leu Thr Val Ser Glu Cys
          35                  40                  45            
 Pro Ser Gln Cys Val Phe Lys Gly Gln Pro Ala Asp Ile Cys Leu Gln
      50                  55                  60                
 Cys Gly Cys Gly Ser Thr Ser Cys Gln Cys Gly Arg Gly Gly Thr Leu
  65                  70                  75                  80
 Ala Ser Ala Trp Glu Cys Ser Leu Glu Gly Ser Val Leu Ser Ser Phe
                  85                  90                  95    
 Arg Leu Ser Trp Arg His His Ser Cys Asn Val Leu
             100                 105            



      <210> 2066
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 2066
 Met Pro Ser Leu Gly Ser Phe Phe Ile Ser Leu Ser Asn Gln Ser Cys
   1               5                  10                  15    
 Leu Pro Met His Lys Lys Ile Ile Leu Ser Ser Tyr Leu Ser Glu Gln
              20                  25                  30        
 Leu Gln Leu Leu Gln Phe Phe Ile Tyr Leu Leu Leu Val Ser Trp Leu
          35                  40                  45            
 Ala Ile Trp Glu Ala Arg Ser Thr His Ala Thr Asn Thr Met Ser Thr
      50                  55                  60                
 Asp Thr His Leu Thr Gly Leu Leu Lys Ala Met Thr Lys Val Cys Lys
  65                  70                  75                  80
 Asn Ser Glu Gln Ser Ser Gly Lys Tyr Glu Ala Pro Met Glu Ala Glu
                  85                  90                  95    
 Lys Ala Gly Pro Ala Ala Asp Glu Glu Lys Glu Pro Glu Ala Leu Thr
             100                 105                 110        
 Gly Pro Gln Tyr Leu His Asn
         115                



      <210> 2067
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 2067
 Met Arg Lys Leu Ser Ser Pro Val Leu Leu Gly Ser Leu Ala Gly Val
   1               5                  10                  15    
 Ala His Leu Pro Leu Val Ser Trp Ala Trp Ser Cys Pro Ile Leu Arg
              20                  25                  30        
 Asp Thr Asn Thr Arg Ser Gly Gln Ser Val Asp Lys Ala Pro Ala Ala
          35                  40                  45            
 Asn Asp Pro Thr Ser Gly Thr Asn Glu Trp Leu Glu Leu Leu Phe Pro
      50                  55                  60                
 Ser Pro His Lys Gly Trp Lys Gly Arg Ser Pro Glu Leu Pro Phe Leu
  65                  70                  75                  80
 Gln Ser Trp Cys Glu Asp Arg Glu Ala Leu Asn Thr Asp Thr Gly Val
                  85                  90                  95    
 Ser Met Ser Met Asp Tyr Leu Cys Lys Ser Lys Gln Asn Lys Arg Met
             100                 105                 110        
 Ala His Pro Ala Asn Ile His Gly Gln Gly Trp Cys Arg Val Leu Asp
         115                 120                 125            
 Ala Glu Met Asn Gly Gly Leu Trp Pro Gln Arg Leu Thr Val Trp His
     130                 135                 140                
 Asp Ser Ala Gln Glu Glu Met Gly Gln Met Leu Gln Lys Glu Gly Ser
 145                 150                 155                 160
 Cys Pro Ser Thr Ala Ala His Asp Ser Arg Val Arg Glu Glu Glu Glu
                 165                 170                 175    
 Val Pro Asp Arg Gly Arg Ala Ile Glu Gly Leu Ser Asn Ala Gln Cys
             180                 185                 190        
 Lys Ala Arg Ser Gln Val
         195            



      <210> 2068
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2068
 Met Arg Ala Ser Val Leu Val Ser Phe Lys Ala Thr Val Val Ser Pro
   1               5                  10                  15    
 Phe Thr Leu Gly Leu Glu Gly Cys Ser Leu Ser Glu Ser Thr Ile Thr
              20                  25                  30        
 Ser Ala Thr Trp Trp Leu Tyr Leu Asn Ala Gly Pro Ser Pro Asp Glu
          35                  40                  45            
 Ala Ala Ser His Gln Arg Pro Gly Arg Gly Gln Lys Gly Pro Ile Pro
      50                  55                  60                
 Thr Ser Glu Lys Glu Met Glu Leu Phe Ala Gly Ser Cys Pro Lys Ala
  65                  70                  75                  80
 Val Ile Trp Trp Gly Gly Ser Ile Leu Leu Ser Asp His Met Leu Pro
                  85                  90                  95    
 Leu Gln Ser Gln Pro Pro Thr Ser Ser Ser Pro Gln Asn Pro Asp Gly
             100                 105                 110        
 Ser Ser Thr Thr Ala Ser Arg Gly Lys Met Asp Ala Leu Thr Gly Cys
         115                 120                 125            
 Asn Leu Glu Gly Asp Arg Ser Met Gln Glu
     130                 135            



      <210> 2069
      <211> 55
      <212> PRT
      <213> Homo sapiens


      <400> 2069
 Met Ala Ala Leu Leu Ser Leu Met Ala Gly Met Ala Thr Val Leu Ala
   1               5                  10                  15    
 Leu Arg Gln Asp Pro Pro Glu Phe Thr Val Trp Phe Leu Leu Phe Leu
              20                  25                  30        
 Asp Leu Thr Thr Glu Leu Gly Ala Trp Glu Glu Trp Pro Gln Phe Ser
          35                  40                  45            
 Pro Asn Ala Gln Glu Asp Ala
      50                  55



      <210> 2070
      <211> 303
      <212> PRT
      <213> Homo sapiens


      <400> 2070
 Met Ala Ala Leu Ala Met Ala Ala Leu Ala Met Ala Thr Leu Thr Met
   1               5                  10                  15    
 Ala Ala Leu Met Met Ala Leu Gly Pro Thr Cys Thr Asp Val Gly Thr
              20                  25                  30        
 Leu Thr Ile Ala Ala Pro Thr Arg Gly Thr Asn Thr Gly Met Phe Thr
          35                  40                  45            
 Ile Pro Ala Pro Thr Trp Gly Arg Ser Leu Phe Gln His Arg His Gly
      50                  55                  60                
 Asp Ala His Tyr Ser Ser Thr Asp Val Gly Thr Leu Ala Ile Ser Ala
  65                  70                  75                  80
 Pro Thr Arg Gly Thr Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr
                  85                  90                  95    
 Arg Gly Thr Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr Arg Gly
             100                 105                 110        
 Arg Ser Leu Phe Gln His Arg His Gly Asp Asp His Tyr Ser Ser Thr
         115                 120                 125            
 Asp Thr Gly Thr Phe Thr Ile Ser Ala Pro Thr Arg Gly Arg Ser Leu
     130                 135                 140                
 Phe Gln His Arg His Gly Asp Ala His Tyr Ser Ser Thr Asp Lys Gly
 145                 150                 155                 160
 His Arg His Gly Asp Ala His Tyr Ser Ser Thr Asp Lys Gly His Arg
                 165                 170                 175    
 Tyr Gly Asp Ala His Ser Thr Ser Thr Asp Thr Gly Thr Leu Thr Ile
             180                 185                 190        
 Ala Ala Pro Thr Arg Gly Thr Asp Met Gly Thr Leu Thr Ile Pro Ala
         195                 200                 205            
 Pro Thr Arg Gly Thr Asp Met Gly Thr Leu Thr Ile Pro Ala Pro Thr
     210                 215                 220                
 Arg Gly Arg Ser Leu Phe Gln His Arg His Gly Asp Thr His Tyr Ser
 225                 230                 235                 240
 Ser Thr Asp Thr Gly His Arg His Gly Asp Ala His Tyr Ser Ser Thr
                 245                 250                 255    
 Asp Thr Gly Thr Leu Thr Ile Pro Ala Pro Thr Arg Gly Thr Asp Thr
             260                 265                 270        
 Gly Thr Leu Thr Val Pro Ala Pro Ile Arg Gly Thr Asn Met Arg Thr
         275                 280                 285            
 Leu Thr Ile Ala Ala Pro Ile Gln Gly Cys Ser Leu Phe Gln Arg
     290                 295                 300            



      <210> 2071
      <211> 203
      <212> PRT
      <213> Homo sapiens


      <400> 2071
 Met Ala Val Lys Gly Glu Leu Leu Leu Gly Val Ala Glu Ala Ala Val
   1               5                  10                  15    
 Val Gln His Pro Gly Leu Ala Val Leu Leu Leu Glu Leu Leu His Leu
              20                  25                  30        
 Val Gly Ala His Asp Ala Gln Ala Leu Gln Leu Asp Ala Ala Gln Leu
          35                  40                  45            
 Phe Val Gln Gln Leu Gln Leu Leu Val His Ala Leu Arg Val Thr Leu
      50                  55                  60                
 Ala Gly Val Gln Gly Ala Ala Arg Val Val Gln Ala Val Arg Gly Gly
  65                  70                  75                  80
 Ala Leu His Leu Ala Leu Glu Leu Gln Glu Leu Ala Glu Ala Leu Ala
                  85                  90                  95    
 Leu Val His Arg Asp Pro Gln Val Val Gly Val Arg Ala Val Gly Arg
             100                 105                 110        
 Asn Glu Arg Leu Val Ala Glu Gly Gln Val Ala Ala Ala Gln Gly Val
         115                 120                 125            
 Leu Ala Ala Gly Glu Leu Pro Leu Pro Arg Gln Arg Val Gly Gly Cys
     130                 135                 140                
 Gly Gly Val Val Ala Ile Val Leu Leu Leu Arg Ala Leu Val Ile Thr
 145                 150                 155                 160
 Gly Ala Leu Val Gly Pro Pro His Thr Ala Val Leu Leu Val Leu Val
                 165                 170                 175    
 Gly Gln Asp Gly Gly Cys Ile Cys Gly Pro Thr Val Phe Val Val Leu
             180                 185                 190        
 Leu Leu His Lys His Lys Asn Lys Gly Ser Gln
         195                 200            



      <210> 2072
      <211> 41
      <212> PRT
      <213> Homo sapiens


      <400> 2072
 Met Leu Lys Glu Leu Leu Leu Leu Leu Leu Tyr Gln Leu Gly Pro Leu
   1               5                  10                  15    
 Ile Asn Glu His Leu Leu His Asp Gly Cys Leu Gly Leu Ala Ala Gln
              20                  25                  30        
 Glu Ala Gly Ala Cys Gly Thr Gly Ser
          35                  40    



      <210> 2073
      <211> 85
      <212> PRT
      <213> Homo sapiens


      <400> 2073
 Met Asn Arg Asp Gly Thr Thr Trp Leu Gln Arg Leu Arg Trp Val Met
   1               5                  10                  15    
 Leu Pro His Leu Gln Met Leu Thr Leu Cys Ile Gln Ser Pro Arg Lys
              20                  25                  30        
 Pro Pro Glu Ser Tyr Tyr Lys Glu Glu Leu Arg Ser His Glu Ser Tyr
          35                  40                  45            
 Tyr Lys Glu Glu Asn Ser Glu Ala Met Lys Val Thr Thr Arg Lys Arg
      50                  55                  60                
 Thr Gln Lys Pro Trp Gly Pro Gln Leu Pro Arg Arg Asp Gln Ala Ala
  65                  70                  75                  80
 Cys Cys Trp Met Leu
                  85



      <210> 2074
      <211> 181
      <212> PRT
      <213> Homo sapiens


      <400> 2074
 Met Gln Ile Leu Ile Gln Trp Leu Trp Glu Ser Thr Arg Ser Ala Leu
   1               5                  10                  15    
 Ala Cys Cys Lys Ser Thr Leu Lys Asp Pro His Gln Ala Pro Arg Arg
              20                  25                  30        
 Arg Ser Val Thr Pro Ala Ala Lys Arg His Gln Cys Pro Phe Pro Gly
          35                  40                  45            
 Cys Thr Lys Ala Tyr Tyr Lys Ser Ser His Leu Lys Ser His Gln Arg
      50                  55                  60                
 Thr His Thr Gly Glu Arg Pro Phe Ser Cys Asp Trp Leu Asp Cys Asp
  65                  70                  75                  80
 Lys Lys Phe Thr Arg Ser Asp Glu Leu Ala Arg His Tyr Arg Thr His
                  85                  90                  95    
 Thr Gly Glu Lys Arg Phe Ser Cys Pro Leu Cys Pro Lys Gln Phe Ser
             100                 105                 110        
 Arg Ser Asp His Leu Thr Lys His Ala Arg Arg His Pro Thr Tyr His
         115                 120                 125            
 Pro Asp Met Ile Glu Tyr Arg Gly Arg Arg Arg Thr Pro Arg Ile Asp
     130                 135                 140                
 Pro Pro Leu Thr Ser Glu Thr Ala Thr Ser His His His Thr Arg Ser
 145                 150                 155                 160
 Val Phe Tyr Leu Gln Ile Arg Val Lys Pro Asp Val Gln Ala Thr Phe
                 165                 170                 175    
 Phe Ala Leu Asn Ile
             180    



      <210> 2075
      <211> 43
      <212> PRT
      <213> Homo sapiens


      <400> 2075
 Met Val Ile Pro Leu Phe Phe Val Phe Gln Pro Pro Leu Gly Gln Leu
   1               5                  10                  15    
 Leu Ala Gln Leu Leu Ser Leu Ala Val Pro Ile Gln Gly Pro Gln Leu
              20                  25                  30        
 Pro Gln Val Glu Val Gln Arg Gln Glu Val Glu
          35                  40            



      <210> 2076
      <211> 255
      <212> PRT
      <213> Homo sapiens


      <400> 2076
 Met Arg Pro Arg Ala Pro Ala Cys Ala Ala Ala Ala Leu Gly Leu Cys
   1               5                  10                  15    
 Ser Leu Leu Leu Leu Leu Ala Pro Gly His Ala Cys Pro Ala Gly Cys
              20                  25                  30        
 Ala Cys Thr Asp Pro His Thr Val Asp Cys Arg Asp Arg Gly Leu Pro
          35                  40                  45            
 Ser Val Pro Asp Pro Phe Pro Leu Asp Val Arg Lys Leu Leu Val Ala
      50                  55                  60                
 Gly Asn Arg Ile Gln Arg Ile Pro Glu Asp Phe Phe Ile Phe Tyr Gly
  65                  70                  75                  80
 Asp Leu Val Tyr Leu Asp Phe Arg Asn Asn Ser Leu Arg Ser Leu Glu
                  85                  90                  95    
 Glu Gly Thr Phe Ser Gly Ser Ala Lys Leu Val Phe Leu Asp Leu Ser
             100                 105                 110        
 Tyr Asn Asn Leu Thr Gln Leu Gly Ala Gly Ala Phe Arg Ser Ala Gly
         115                 120                 125            
 Arg Leu Val Lys Leu Ser Leu Ala Asn Asn Asn Leu Val Gly Val His
     130                 135                 140                
 Glu Asp Ala Phe Glu Thr Leu Glu Ser Leu Gln Val Leu Glu Leu Asn
 145                 150                 155                 160
 Asp Asn Asn Leu Arg Ser Leu Ser Val Ala Ala Leu Ala Ala Leu Pro
                 165                 170                 175    
 Ala Leu Arg Ser Leu Arg Leu Asp Gly Asn Pro Trp Leu Cys Asp Cys
             180                 185                 190        
 Asp Phe Ala His Leu Phe Ser Trp Ile Gln Glu Asn Ala Ser Lys Leu
         195                 200                 205            
 Pro Lys Gly Leu Ala Gly Val Asp Tyr Leu Cys Val Pro Gly Lys Arg
     210                 215                 220                
 Asn Ala Ala Tyr Ser Met Gly Asn Gly Arg Ile Leu Ser Thr Val His
 225                 230                 235                 240
 Gly Glu Ser Ala Ser Ser Lys Gly Ser Pro Ala Ala Ser Arg Ala
                 245                 250                 255



      <210> 2077
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2077
 Met Gly Ile Tyr Gln Met Tyr Leu Cys Phe Leu Leu Ala Val Leu Leu
   1               5                  10                  15    
 Gln Leu Tyr Val Ala Thr Glu Ala Ile Leu Ile Ala Leu Val Gly Ala
              20                  25                  30        
 Thr Pro Ser Tyr His Trp Asp Leu Ala Glu Leu Leu Pro Asn Gln Ser
          35                  40                  45            
 His Gly Asn Gln Ser Ala Gly Glu Asp Gln Ala Phe Gly Asp Trp Leu
      50                  55                  60                
 Leu Thr Ala Asn Gly Ser Glu Ile His Lys His Val His Phe Ser Ser
  65                  70                  75                  80
 Ser Phe Thr Ser Ile Ala Ser Glu
                  85            



      <210> 2078
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 2078
 Met Pro Leu Thr Ala Ala Ala Ser Thr Val Phe Arg Met Thr Asn Phe
   1               5                  10                  15    
 Leu Met Ala Leu Ser Leu Gly Met His Arg Ala His Ala Gln Cys Thr
              20                  25                  30        
 Lys Val Phe His Cys Phe Trp Asn Phe Val Gly Lys Gln Leu Glu Gly
          35                  40                  45            
 Ala Ala Trp Ala Lys Gly Val Thr Ile Asn Asn Asp Val Lys Arg Thr
      50                  55                  60                
 Gln Trp Arg
  65        



      <210> 2079
      <211> 128
      <212> PRT
      <213> Homo sapiens


      <400> 2079
 Met Ala Phe Gly Gly Gln Leu Phe Ala Tyr Ala Ser Arg Ser Ile His
   1               5                  10                  15    
 Thr Ala Phe Leu Phe Cys Ser Glu Pro Leu Ala Tyr Tyr Arg Ile Gln
              20                  25                  30        
 Leu Val Lys Thr Arg Glu Arg Leu Asp Lys Phe Ala Ser Ile Arg Ile
          35                  40                  45            
 Pro Gly Ser Lys Lys Glu Arg Pro Pro Leu Pro Asn Leu Lys Thr Ala
      50                  55                  60                
 Phe Ala Ser Ser Asp Cys Ser Ala Ala Pro Leu Glu Met Met Glu Asn
  65                  70                  75                  80
 Phe Pro Lys Pro Leu Ser Glu Asn Glu Leu Leu Glu Leu Phe Glu Lys
                  85                  90                  95    
 Met Met Lys Ser Pro Leu Lys Ser Tyr Leu Gly Val Ile Val Asp Leu
             100                 105                 110        
 Ile Lys Ala Ser Val Thr Ser Ile Tyr Phe Ser Ile Phe Ile Ser Ser
         115                 120                 125            





      <210> 2080
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 2080
 Met Ser Glu Phe Leu Leu Ala Leu Leu Thr Leu Ser Gly Leu Leu Pro
   1               5                  10                  15    
 Ile Ala Arg Val Leu Thr Val Gly Ala Asp Arg Gly Tyr Glu Glu His
              20                  25                  30        
 Leu Asn Arg Val Pro Lys Arg Gln Leu Gly Val Ile Asn Pro Phe Lys
          35                  40                  45            
 His Tyr Leu Ile Tyr Ile Ala Gly Pro Ala Ala Leu Trp Lys Asn Ile
      50                  55                  60                
 Leu Tyr Phe Asn Gln Arg Asn Tyr Leu Gly Asn Ala Thr
  65                  70                  75        



      <210> 2081
      <211> 149
      <212> PRT
      <213> Homo sapiens


      <400> 2081
 Met Thr Phe Leu Ile Leu Ser Ile Ala Pro Val Leu Ala Val Thr Gly
   1               5                  10                  15    
 Met Ile Glu Thr Ala Ala Met Thr Gly Phe Ala Asn Lys Asp Lys Gln
              20                  25                  30        
 Glu Leu Lys His Ala Gly Lys Ile Ala Thr Glu Ala Leu Glu Asn Ile
          35                  40                  45            
 Arg Thr Ile Val Ser Leu Thr Arg Glu Lys Ala Phe Glu Gln Met Tyr
      50                  55                  60                
 Glu Glu Met Leu Gln Thr Gln His Arg Asn Thr Ser Lys Lys Ala Gln
  65                  70                  75                  80
 Ile Ile Gly Ser Cys Tyr Ala Phe Ser His Ala Phe Ile Tyr Phe Ala
                  85                  90                  95    
 Tyr Ala Ala Gly Phe Arg Phe Gly Ala Tyr Leu Ile Gln Ala Gly Arg
             100                 105                 110        
 Met Thr Pro Glu Gly Met Phe Ile Asp Tyr Pro Glu Glu Thr Asp Lys
         115                 120                 125            
 Asp Lys Ile Arg Arg Leu Asn Gln Pro Leu Lys Gly Pro Lys Glu Glu
     130                 135                 140                
 Lys Ser Lys Asp Ser
 145                



      <210> 2082
      <211> 69
      <212> PRT
      <213> Homo sapiens


      <400> 2082
 Met Ser Gln Tyr Lys Val Thr Thr Ile Val Pro Cys Ser Met Phe Ala
   1               5                  10                  15    
 Ile Thr Leu Val Thr Asn Thr Ser Val Ser Val Glu Pro Ile Ile Arg
              20                  25                  30        
 Gln Leu Thr Arg Lys Val Gly Val Met Asn Arg Thr Ser Gln Ser Leu
          35                  40                  45            
 His Leu Leu Gly Arg Thr Ala Phe Ser Ser Tyr Leu Asn Asp Gly Met
      50                  55                  60                
 Glu Asp Ile Val Val
  65                



      <210> 2083
      <211> 546
      <212> DNA
      <213> Homo sapiens


      <400> 2083
 attcattaag catctttaaa tcagaacaca cgcaatattc aagctattct gtaaactccc     60
 cgaagcagaa atattgtctt atttactact aaatccccag tatctagtat aatgagatct    120
 atgatggata ctaaagagat attataataa gtaattaccc atttttacag aaaattatgt    180
 tttttatcat cccgcatcca tgcagtcatg gctacatcct cttgcctcta ccttatgcca    240
 tgcctactgg ccagaggcct agcgctaccc tgatgtccta aagagtttct gctgctgctg    300
 ccactaccaa caccaccaca ctgctatatg atgaggagac ctgtacactg tgccactgac    360
 aaggagggga tattagcacc taagcatttc caggcagcag ctggggaagc cagaacctcc    420
 acagacagat ctggtgcaca ggcacaaagg tcagttactc cttgtcagtg gcacagtgta    480
 caggactcct caacatatag cagtgtggtg gtggtggtag tggcagcagc agcagaaact    540
 ctttag                                                               546



      <210> 2084
      <211> 702
      <212> DNA
      <213> Homo sapiens


      <400> 2084
 cccctctgcc ttccaggggc cctgcaatgc gctttcaggc ccagcctttc ctcacaggcc     60
 aggctttgtt ctccatctcg gcctgtctgc tgcccacctt ccctttctct cccctcctgt    120
 ggctttcagg aacatctctg gtttggctcc tgtgaccttt gacctgctga tgccccttcc    180
 ttggctgcat ttcctggaga cccacagtat gatcccccct actgctatcc agggacacag    240
 tgctgggtcc ctggagaggg aatgctcctg ctgtctcaga ccctctgcct aggggagcag    300
 gtgctgctgg gggcctggct ggtatggggg cccagccggg accccaggcc cctgccgtat    360
 ctgtgccatg acgagcccta cacatttgac atcaacctct ctgttaacct gaaaggccct    420
 ggaaacagat tgggagagcc gatccccatt tccaaggccc atgagcacat ttttggaatg    480
 gtccttatga acgactggag tggtaattac tggagctctg ttcctgtaaa gatgaccggg    540
 aaggagctgg ggacttgggg caatttcata aaagctgaag attggtgcag gtcaaaaggg    600
 gcagtaatgg cattaccgcg agcggtgact cctacgcgcg caattaacga atccaccatc    660
 ggggcagctg gtgtcgataa cgaagtatct tcaaccggtt ga                       702



      <210> 2085
      <211> 9502
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(9502)
      <223> n = a,t,c or g


      <400> 2085
 atgcagtggt cagtgataat ggaatacttg aaagtaatcc cctcactcca ggaactagtg     60
 ctcagctagc agaactaata gccctcactt gggcactaga attaggagaa gaaaaaaggg    120
 caaatatata tacagactct aaatatgctt acctagtcct ccatgcccat gcagcaatat    180
 ggaaagaaag ggaattccta acttctgaga gaacacctat caaacatcag gaagccatta    240
 ggaaattatt attggctgta cagaaaccta aagaggtggc agtcttacac tgccggggtc    300
 atcanaaagg aaaggaaagg gaaaatactt ttgcctgcaa ctatccaatg gaaattactt    360
 aaaacccttc atcaaacctt tcacttaggc atcgatagca cccatcaaat ggccaaatca    420
 ttatttactg gaccaggcct tttcaaaact atcaagcaaa tattcagggc ctgtgaattg    480
 tgccaaaaaa ataatcccct gcctcatcgc caagctcctt caggaaaaca aaaaacaggc    540
 cattaccctg aaaaaaactg gcaactgatt ttacccacaa gcccaaacct cagggatttc    600
 agtatctact agtctgggta aatactttca cgggttgggc aaaggccttc ccctgtagga    660
 cagaaaaggc ccaagaggta ataaaggcac tagttcatga aataattccc agattcggac    720
 ttccccgagg cttacagagt gacaatagcc ctgctttcca ggccacagta acccagggag    780
 tatcccaggc gttaggtata cgatatcact tacactgcgc ctgaaggcca cagtcctcag    840
 ggaaggtcga gaaaatgaat gaaatactca aaggacatct aaaaaagcaa acccaggaaa    900
 cccacctcac atggcctgct ctgttgccta tagccttaaa aagaatctgc aactttcccc    960
 aaaaagcagg acttagccca tacgaaatgc tgtatggaag gcccttcata accaatgacc   1020
 ttgtgcttga cccaagacag ccaacttagt tgcagacatc acctccttag ccaaatatca   1080
 acaagttctt aaaacattac aaggaaccta tccctgagaa gagggaaaag aactattcca   1140
 cccttgtgac atggtattag tcaagtccct tctctctaat tccccatccc taggatacat   1200
 cctgggggaa gggaccctta cccagttcat ttttatttta ccccaattgc gggtttaaag   1260
 tggctggagt ggtcttggat acatcacact tgagtcaaat cctggatact gccaaaggaa   1320
 cctgaaaatc caggagacaa cgctagctat tcctgtgaac ctctagagga tttgcgcctg   1380
 ctcttcaaac aacaaccagg aggaaagtaa ctaaaatcat aaatccccca tggccctccc   1440
 ttatcatatt tttctcttta ctgttctttt accctctttc actctcactg caccccctcc   1500
 atgccgctgt atgaccagta gctcccctta ccaagagttt ctatggagaa tgcagcgtcc   1560
 cggaaatatt gatgccccat cgtataggag tctttctaag ggaaccccca ccttcactgc   1620
 ccacacccat atgccccgca actgctatca ctctgccact ctttgcatgc atgcaaatac   1680
 tcattattgg acaggaaaaa tgattaatcc tagttgtcct ggaggacttg gagtcactgt   1740
 ctgtcggact tacttcaccc aaactggtat gtctgatggg ggtggagttc aagatcaggc   1800
 aagagaaaaa catgtaaaag aagcaatctc ccaactgacc cggggacata gcacccctag   1860
 cccctacaaa ggactagttc tctcaaaact acatgaaacc ctccgtaccc atactcgcct   1920
 ggtaagccta tttaatacca ccctcactgg gctccatgag gtctcggccc aaaaccctac   1980
 taactgttgg atatgcctcc ccctgaactt caggccatat gtttcaatcc ctgtacctga   2040
 acaatggaac aacttcagca cagaaataaa caccacttcc gttttagtag gacctcttgt   2100
 ttccaatctg gaaataaccc atacctcaaa cctcacctgt gtaaaattta gcaatactac   2160
 atacacaacc aactcccaat gcatcaggtg ggtaactcct cccacacaaa tagtctgcct   2220
 accctcagga atattttttg tctgtggtac ctcagcctat cgttgtttga atggctcttc   2280
 agaatctatg tgcttcctct cattcttagt gccccctatg accatctaca ctgaacaaga   2340
 tttatacagt tatgtcaata tcctaaagcc cccgcaacaa aagagtaccc attcttcctt   2400
 ttgttattgg agcaggagta ctaggcggac taggtactgg cattggcggt attacaacct   2460
 ctactcagtt ctaccacaaa ctatctcaag aactaaatgg tgacatggaa caggtcgccc   2520
 gactcccctg gtcaccttgc aagatcaact taactcccta gcagcagtag tccttcaaaa   2580
 tcgaagagct ttagacttgc taaccgctga aagaggggga acctgtttac ttttagggga   2640
 agaatgctgt tactatgtta atcaatccgg aatcgtcact gagaaagtta aagaaattcg   2700
 agatcgaata caacgtagag cagaggagct tcgaaacact ggaccctggg gcctcctcag   2760
 ccaatggatg ccctggattc tccccttctt aggacctcta gcagctataa tattgctact   2820
 cctctttgga ccctgtatct ttaacctcct tgttaacttt gtctcttcca gaatcgaagc   2880
 tgtaaaacta caaatggagc ccaagatgca gtccaagact aagatctacc gcagacccct   2940
 ggaccggcct gctagcccac gatctgatgt taatgacatc aaaggcaccc ctcctgagga   3000
 aatctcagct gcacaacctc tactacgccc caattcagca ggaagcagtt agagcggtcg   3060
 tcggccaacc tccccaacag cacttaggtt ttcctgttga gatgggggac tgagagacag   3120
 gactagctgg atttcctagg ctgactaaga atccctaagc ctagctggga aggtaaccac   3180
 atccaccttt aaacacgggg cttgcaactt agctcacacc cgaccaatca ggtagtaaag   3240
 agagctcact aaaatgctaa ttaggcaaaa acaggaggta aagaaatagc caatcatcta   3300
 ttgcctgaga gcacagcggg agggacaatg atcaggatat aaacccaggc attccagcca   3360
 gcaacggcta ccctctttgg gtcccctccc tttgtatggg agctctgttt ccactctatt   3420
 aaatcttgca actgcactct cttctggtcc gtgtttgtta cggattgagc tgagcttttg   3480
 cttattgtcc accattgttc tttgccgctg ttgcagacct gccactgact tccatccctc   3540
 tggatcctgc agggtgtccg ctgtgctcct gatccagcga ggcgcccatt gccgctcccg   3600
 atcgggctaa aggcttgcca ttgttcctgc acggctaagt gcctgggttt gttctaattg   3660
 agctgaacac taatcactgg gttccatggt tctcttctgt gacccacggc ttctaataga   3720
 actataacac ttaccacatg gcccaagatt ccattccttg gaatccgtga ggccaagaac   3780
 tccaggtcag agaatacgag gcttgccacc atcttggaag cggcctgcta ccgtcttgga   3840
 agtggttcac caccatcttg ggagctctgt gagcaaggac cccccggtaa cattttggca   3900
 accaacgacg gacatccaaa gtgatgggaa acgttccccg caagacaaaa acgcccctaa   3960
 gacgtattct ggagaattgg gaccaatttg accctcagac actaaggaaa gaaacgactt   4020
 atattcttct gcagtgccgc ctggcactcc tgagggaagt ataaattata acaccatctt   4080
 acagctagac ttcttttgta gaaaaggcaa atggagtgaa gtgccataag tacaaacttt   4140
 cttttcatta agagacaact cacaattatt gtaaaaagtg tgatttatgc ccctacaggg   4200
 aagccttcag agtctacctc ccctatcccc agcatccccg actccttccc caactaataa   4260
 ggacccccct tcaacccaaa tggtccaaaa ggagatagac aaaagggtaa acagtgaacc   4320
 aaagagtgcc aatattcccc aattatgacc cctcccaagc agtgggagga agagaattcg   4380
 gcccagccag agtgcatgtg cctttttctc tcccagactt aaagcaaata aaaacagact   4440
 taggtaaatt ctcagataac cctgatggct atattggtgt tttacaaggg ttaggacaat   4500
 tctttgatct gacatggaga gatatatatg tcactgctaa atcagacact aaccccaaat   4560
 gagagaagtg ccaccataac tgcagcctga gagtttggcg atctctggta tctcagtcag   4620
 gtcaatggat aggatgacaa cagaaggaaa gagatgattc cccacaggcc agcaggcagt   4680
 tcccagtcta gaccctcatt ggggacacag aaatcagtaa catgggagat tggtgctgca   4740
 gacatttgct aacttgtgtg ctacaaggac taaggaaaac tacgaagaaa atctacgaat   4800
 tactcaatga tgtccaccat aacacagggg aagggaagaa aatcctactg cctttctgga   4860
 gagactaagg gaggcattga ggaagcgtgc ctctctgtca cctgactctt ctgaaggcca   4920
 actaatctta aagcgtaagt ttatcactca gtcagctgca gacattagaa aaaacttcaa   4980
 aagtctgccg taggcccgga gcaaaactta gaaaccctat tgaacttggc aacctcggtt   5040
 ttttataata gagatcagga ggagcaggcg gaacaggaca aacgggatta aaaaaaaggc   5100
 caccgcttta gtcatgaccc tcaggcaagt ggactttgga ggctctggaa aagggaaaag   5160
 ctgggcaaat tgaatgccta atagggcttg cttccagtgc ggtctacaag gacactttaa   5220
 aaaagattgt ccaagtagaa gtaagccgcc ccttcgtcca tgccccttat ttcaagggaa   5280
 tcactggaag gcccactgcc ccaggggaca aaggtctttt gagtcagaag ccactaacca   5340
 gatgatccag cagcaggact gagggtgcct ggggcaagcg ccatcccatg ccatcaccct   5400
 cacagagccc tgggtatgct tgaccattga gggccaggaa ggttgtctcc tggacactgg   5460
 tgcggtcttc ttagtcttac tcttctgtcc cggacaactg tcctccagat ctgtcactat   5520
 tctgaggggg tcctaagacg ggcagtcact agatactttt tcccagccac taagttatga   5580
 actggggagc tttattcttt tcacatgctt ttctaattat gcttgaaagc cccactacct   5640
 tgttagggag agacattcta gcaaaagcag gggccattat acacctgaac ataggagaag   5700
 gaacacccgt ttgttgtccc ctgcttgagg aaggaattaa tcctgaagtc tgggcaacag   5760
 aaggacaata tggacgagcc aaagaatgcc cgtcctgttc aagttaaact aaaggattcc   5820
 acctcctttc cctaccaaag gcagtacccc ctcagaccca aggcccaaca aagggcttcc   5880
 aaaagattgt taaggactta aaagcccaag gcttagtaaa accatgcata actccctgca   5940
 gtaattccgt agtggattga ggaggcacag aaacccagtg gacagtggag ggttagtgca   6000
 agatctcagg attatcaatg gaggccgttg tccttttata cccagctgta cctagccctt   6060
 atactgtgct ttcccaaata ccagaggaag cagagtggtt tacactcctg gaccttaagg   6120
 atgccttctt ctgcatccct gtacatcctg actctcaatt cttgtttgcc tttgaagata   6180
 cttcaaaccc aacatctcaa ctcacctgga ctgttttacc ccaagggttc agggatagcc   6240
 cccatctatt tggccaggca ttagcccaag acttgagcca atcctcatac ctggacactt   6300
 gtccttcggt aggtggatga tttacttttg gccgcccatt cagaaacctt gtgccatcaa   6360
 gccacccaag cgctcttcaa tttcctcgct acctgtggct acatggtttc caaaccaaag   6420
 gctcaactct gctcacagca ggttacttag ggctaaaatt atccaaaggc accagggccc   6480
 tcagtgagga acacatccag cctatactgg cttatcctca tcccaaaacc ctaaagcaac   6540
 taaggggatt ccttggcgta ataggtttct gccgaaaatg gattcccagg tttggcgaaa   6600
 tagccaggtc attaaataca ctaattaagg aaactcagaa agccaatacc catttagtaa   6660
 gatggacaac tgaagtagaa gtggctttcc aggccctaac ccaagcccca gtgttaagtt   6720
 tgccaacagg gcaagacttt tcttcatatg tcacagaaaa aacaggaata gctctaggag   6780
 tccttacaca gatccgaggg atgagcttgc aacctgtggc gtacctgact aaggaaattg   6840
 atgtagtggc aaagggttga cctcattgtt tacgggtagt ggtggcagta gcagtcttag   6900
 tatctgaagc agttaaaata atacagggaa gagatcttac tgtgtggaca tctcatgatg   6960
 tgaatggcat actcactgct aaaggagact tgtggctgtc agacaactgt ttacttaaat   7020
 gtcaggctct attacttgaa gggccagtgc tgcgactgtg cacttgtgca actcttaacc   7080
 cagccacatt tcttccagac aatgaagaaa agataaaaca taactgtcaa caagtaattt   7140
 ctcaaaccta tgccactcga ggggaccttt tagaggttcc tttgactgat cccgacctca   7200
 acttgtatac tgatggaagt tcctttgtag aaaaaggact tcgaaaagtg gggtatgcag   7260
 tggtcagtga taatggaata cttgaaagta atcccctcac tccaggaact agtgctcagc   7320
 tagcagaact aatagccctc acttgggcac tagaattagg agaagaaaaa agggcaaata   7380
 taatacagac tctaaatatg cttacctagt cctccatgcc catgcagcaa tatggaaaga   7440
 aagggaattc ctaacttctg agagaacacc tatcaaacat caggaagcca ttaggaaatt   7500
 attattggct gtacagaaac ctagagaggt ggcagtctta cactgccggg gtcatcacaa   7560
 aggaaaggaa agggaaatac aagagaactg ccaagcatat attgaagcca aaagagctgc   7620
 aaggcaggac cctccattag aaatgcttat taaacttccc ttagtatagg gtaatccctt   7680
 ccgggaaacc aagccccagt actcagcagg agaaacagaa tggggaacct cacgaggcag   7740
 ttttctcccc tcgggacggt tagccactga agaagggaaa atacttttgc ctgcaactat   7800
 ccaatggaaa ttacttaaaa cccttcatca aacctttcac ttaggcatcg atagcaccca   7860
 tcagatggcc aaatcattat ttactggacc aggccttttc aaaactatca agcagatagt   7920
 cagggcctgt gaagtgtgcc agagaaataa tcccctgcct tatcgccaag ctccttcagg   7980
 agaacaaaga acaggccatt accctggaga agactggcaa ctgattttac ccacaagccc   8040
 aaacctcagg gatttcagta tctactagtc tgggtagata ctttcacggg ttgggcagag   8100
 gccttcccct gtaggacaga aaaggcccaa gaggtaataa aggcactagt tcatgaaata   8160
 attcccagat tcggacttcc ccgaggctta cagagtgaca atagccctgc tttccaggcc   8220
 acagtaaccc agggagtatc ccaggcgtta ggtatacgat atcacttaca ctgcgcctga   8280
 aggccacagt cctcagggaa ggtcgagaaa atgaatgaaa cactcaaagg acatctaaaa   8340
 aagcaaaccc aggaaaccca cctcacatgg cctgttctgt tgcctatagc cttaaaaaga   8400
 atctgcaact ttccccaaaa agcaggactt agcccatacg aaatgctgta tggaaggccc   8460
 ttcataacca atgaccttgt gcttgaccca agacagccaa cttagttgca gacatcacct   8520
 ccttagccaa atatcaacaa gttcttaaaa cattacaagg aacctatccc tgagaagagg   8580
 aaaagaatat tccacccaag tgacatggta ttagtcaagt cccttccctc taattcccca   8640
 tccctagata catcctggga aggaccctac ccagtcattt tatctacccc aactgcggtt   8700
 aaagtggctg gagtggagtc ttggatacat cacacttgag tcaaatcctg gatactgcca   8760
 aaggaacctg aaaatccagg agacaacgct agctattcct gtgaacctct agaggatttg   8820
 cgcctgctct tcaaacaaca accaggagga aaaatcgaag ctgtaaaact acaaatggag   8880
 cccaagatgc agtccaagac taagatctac cgcagacctc tggaccagcc tgctagccca   8940
 catgctccga tgttaatgac atcgaaggca cccgtctcga ggaaatctca actgcacaac   9000
 ccctactaca ccccaattca gcaggaagca gttagagcgg tcgtcagcca acctccccag   9060
 cagcacttgg gttttcctgt tgagagcggg gactgaaaga caggactagc tggatttcct   9120
 aggctgacta agaatcccta agcctagctg ggaaggtgac tgcatccacc tttaaacaca   9180
 gggcttgcaa cttagctcac acccgaccaa tcaggtagta aagagagctc actaaaatgc   9240
 taattaggca aaaacaggag gtaaagaaat agccaatcat ctattgtctg agagcacagc   9300
 gggagggaca atgaccggga tttaaaccca ggcattcgag ctggcaacgg ctaccctctc   9360
 tgggtcccct ccctttgtat gggagctctg ttttcactct attaaatctt gcaactgcac   9420
 actcttctgg tccgtgtttg ttacggcttg agctgagctt tcgctcactg tccaccactg   9480
 ctgtttgctg ctgtcgcaaa cc                                            9502



      <210> 2086
      <211> 2497
      <212> DNA
      <213> Homo sapiens


      <400> 2086
 ttccatcatt ctatatatgt gatggtgaaa gatatgcctg gaaaagtttt gttttgaaaa     60
 gtttattttc tgcttcgtct tcagttggca aaagctctca attctttagc ttccagtttc    120
 ttttctctct ttttctttgt taggtaatta aaggtatgta aacaaattat ctcatgtagc    180
 aggggatttt catgttgaga ggaatcttcc gtgtgagttg tttggtcaca caaataaccc    240
 tttctcaatt ttaggagttt ggattgtcaa atgtaggttt ttctcaaagg gggcatataa    300
 ctacatattg actgccaaga actatgactg tagcactaat cagcacacat agagccacac    360
 aattatttaa tttctaactc tctgtggtcc ctagaaaaat tcccgttgat gtgcttaggt    420
 taaagttctg aagatacccg ttgtaccctt acttggaaag tttccaatcc taaagttttt    480
 atggaaatgc caataatatg gtaatcagct agcaatattt ctgtgatcac caacaactct    540
 cagtttgatc ttaaagtctg aataataaaa caaatcccag cagtaataca tttcttaaac    600
 ctcacagtgc atgatatatc ttttcattct gatcctgtgt ttgcaaaaat atacacatgt    660
 atatcatagt tcctcacttt ttattcattt gttttcctat tacctgtagt aaatatatta    720
 gttagtacat ggaatttata gcatcagcta cccccaggaa cagcacctga caggcggggg    780
 attttttttc aagttgttct acatttgcat aaattatttc tattattatt catgtatgtt    840
 atttatttct gaatcacact agtcctgtga aagtacaact gaaggcagaa agtgttagga    900
 ttttgcatct aatgttcatt atcatggtat tgatggacct aagaaaataa aaattagact    960
 aagcccccaa ataagctgca tgcatttgta acatgattag tagatttgaa tatatagatg   1020
 tagtattttg ggtatctagg tgttttatca ttatgtaaag gaattaaagt aaaggacttt   1080
 gtagttgttt ttattaaata tgcatatagt agagtgcaaa aatataggca aaaataaaaa   1140
 ctaaaggtag aaaagcattt tagatatgcc ttaatttaga aactgtgcca gggtggccct   1200
 cgggaataga tgccagggca gagacccagt gcctggggtg gtgcctcctc ttgtctgccc   1260
 tcatggaagg aagcttccct cacgtggatg tagtgccctc gtagggtgtc atgtggaagt   1320
 aagtgggaac acggcagtac ctgttgaaga aggaagagca gtgtgaagaa gtttttcctg   1380
 taagaagcag aactgtccag cttgttgccc tttgaagctt cccaagaacc gtgtccagaa   1440
 tggaagaaag tcccaagttt tccaatgcct tcaggcaacc ttagcctgtg taccagaagc   1500
 aatcccagtg tgggtaataa aaaagccaag gattgcccct gtaataaatt taattaataa   1560
 aaataaaaag gggattttaa accaacccca acaatccccc caacaccctc aaaagccttg   1620
 ttgccatttt ttgggtattt gaaggttttt atcctgaagg ttaaaagggc aagtgtttgg   1680
 tatagaagag cagtatgtgt ttaagaaaag gaaaaatatt gggttcgcgt agagtgcaaa   1740
 attagaacta gaaagtttta tacggattat cattttggag atgtgttaaa gtaggttttc   1800
 actggtaaaa tgtattagtg tttctgcatt gccatagggc ctggttaaaa ctttctctta   1860
 ggtttcagga agactgtcac atacaggaga gctttttggc ttctgactta taatagaaaa   1920
 tgttttgaaa gtaaaaaaaa aaaaaaatct aatttggaaa tttgacttgt tagtttctgt   1980
 gtttgaaatc atggttctag aaatgtagaa attgtgtata tcagatactc atctaggctg   2040
 tgtgaaccag cccaagatga ccaacaatcc ccacacctct acatctctgt cccctgtatc   2100
 tcttcctttc taccactaaa gtgttccctg ctacccatcc tgggcttgtc cacatggtgc   2160
 tctccatctt cctccacatc atgggaccac aggtgtggcc tgtctaggcc tgggccacca   2220
 cttcccaact tggacctagg ccacattcat ctaggaggat ggggtcctgg atgctggggc   2280
 acagactgtg cttcatgggc acccattagg aaaatggcct ctaggcattc tttgtatggc   2340
 atcttggatt ttttaaacca agttcattgt tacagaggca tttcagtttt gggtgtgggt   2400
 accaaggagg aaaaattaat caaggattat taaaccacat tccagggctg gctgttttct   2460
 ctccatctta cagggccaca atttttactg tattttt                            2497



      <210> 2087
      <211> 391
      <212> DNA
      <213> Homo sapiens


      <400> 2087
 cgccgccacc ggcgccacgt attcctacat agccactggc gccaccacac gctcctacgc     60
 caccaccagc gctcccactt cccccaaggc cgccaatggt gcccctactt ctccccacac    120
 cgtcactggt gctaccacat gctcctacac caccaccagc acccccactt ccccgacact    180
 gccacaggca cccccacttc ccccaacgcc gccactggtg cccctacttc tctccacccg    240
 ccactggcac caacacctcc ttctacgcca ccaccaggcg ccccactatc tgcaatgacg    300
 ccaccagcgc cccttctccc cacgccgcca ctggcactac cagctgctcc tacgccgcca    360
 ccggcgcccc cacccctccc aatgccgcca c                                   391



      <210> 2088
      <211> 660
      <212> DNA
      <213> Homo sapiens


      <400> 2088
 ggcacgagat cctttgttag agcaagtgga attacctgct gtggcatcag tcagtgcttc     60
 agtaattaaa tctccatcag atccctcaca tgtttctgtt ccaccacctc cattgttact    120
 tccagctgcc accacaagga gtaacagtac atctatgcac agtagcattc ccagtataga    180
 gaacaaacct ccacaggcta ttgttaaacc acagatccta acccatgtta ttgaaggctt    240
 tgtgattcag gagggattgg agccatttcc tgtgagtcgt tcctctttgc taatagaaca    300
 gcctgtgaaa aaacggcctc ttttggataa tcaggtgata aattcagtgt gtgttcagcc    360
 agagctataa aactgatttt aagatattta caatatatgg gacgattttc gctgaattag    420
 atagtggttg tgatattata taaagaaaaa aatggctgag gacaaatgta gaaaagaatt    480
 gatcagtgat cgtgcatttc actaaagcgt tctattgctt tagtgaagca tactcagtat    540
 cttcagtatc agtagaaaag atactcagta tcttttcagt ttgggatatg atggtcactg    600
 atggccatca gcattcattg cccagtgtgt gaggccacta tggatgaaag ttgactattg    660



      <210> 2089
      <211> 648
      <212> DNA
      <213> Homo sapiens


      <400> 2089
 ggcacgaggg tgcatttggg cctcaggaac caggggaata gaggcttgaa tgtggtccgc     60
 acaccctctc gctgtcttgt ccctcaagtt gactttattc tctctcactt cagattggct    120
 ttcttcaaaa gacatggcaa taagcttggc cttcaagatt tcccagattt tatgttctgt    180
 cctatctgcc cctggaaaaa ggctaatttc agttctgtgg aacacaagtt ctttgaaaag    240
 gtcctgaatg aggaagagac ctactgttgt aggcaaataa tatgaatcat attacatatg    300
 tcttttccct tcatatacat ctgtttagtt ttgcagtggc tcctgggata agatgctaaa    360
 gatctggtct acaggtaaat taaatattta ttttaccttg acttaataat gctgcttcaa    420
 aaatttaaat tcggaggcta tatggtggct tacgcctata atctcagcac ttcaagaagc    480
 cagggtaaaa ggatcacttg aggccacgag ttcgagagca ccctaagcca catagtgaga    540
 cccccgctct actagaggag aaaataaaat taccaggtgt gggggaggcc cccggaaacc    600
 taactccttg ggagttgaag gaaggaaatg ttaacccccc gggggggg                 648



      <210> 2090
      <211> 7502
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(7502)
      <223> n = a,t,c or g


      <400> 2090
 gcatgctcga cgcgccatgt gatggatatc tgcagaattc ggcttactca ctatagggct     60
 cgagcggccg cccgggcagg tcgccagtat gttggagttg gtggtggctt aagttttgaa    120
 gggaggtagc atccgttgga tatccacacc atccttctcg ctgcaggctt tcttggactc    180
 cgtactgttg gtgtaaccaa ggcctggagg tctgggtggc tcaggtttcc tgcagccatg    240
 tttctgtaca acttaacctt gcagagagcc actggcatca gctttgccat tcatggaaac    300
 ttttctggaa ccaaacaaca agaaattgtt gtttcccgtg ggaagatctt gggagctgct    360
 tcgcccagac cccaacactg gcaaagtaca taccctactc actgtggaag tattcggtgt    420
 tatccggtca ctcatggcct ttaggctgac aggtggcacc aaagactaca ttgtagttgg    480
 cagtgactct ggtcgaattg ttattttgga ataccagcca tctaagaata tgtttgagaa    540
 gattcaccaa gaaacctttg gcaagaggtg gaggccgtag catcgttcct ggccagttct    600
 tagctgtgga tcccaaaggg cgagccgtta tgattagtgc cattgagaaa cagaaattgg    660
 tgtatatttt gaacagagat gctgcagccc gacttaccat ttcatctccc ctggaagccc    720
 acaaagcaaa cactttagtg tatcatgtag ttggagtaga tgtcggattt gaaaatccaa    780
 tgtttgcttg tctggaaatg gattatgagg aagcagacaa tgatccaaca ggggaagcag    840
 cagctaatac ccagcagaca cttactttct atgagctaga ccttggttta aatcatgtgg    900
 tccgaaaata cagtgaacct ttggaggaac acggcaactt ccttattaca gttcctggag    960
 ggtcagatgg tccaagtgga gtactgatct gctctgaaaa ctatattact tacaagaact   1020
 ttggtgacca gccagatatc cgctgtccaa ttcccaggag gcggaatgac ctggatgacc   1080
 ctgaaagagg aatgattttt gtctgctctg caacccataa aaccaaatcg atgttcttct   1140
 ttttggctca aactgagcag ggagatatct ttaagatcac tttggagaca gatgaagata   1200
 tggttactga gatccggctc aaatattttg atactgtacc cgttgctgct gccatgtgtg   1260
 tgcttaaaac agggttcctt tttgtagcat cagaatttgg aaaccattac ttatatcaaa   1320
 ttgcacatct tggagatgat gatgaagaac ctgagttttc atcagccatg cctctggaag   1380
 aaggagacac attctttttt cagccaagac cacttaaaaa ccttgtgctg gttgatgagt   1440
 tggacagcct ctctcccatt ctgttttgcc agatagctga tctggccaat gaagatactc   1500
 cacagttgta tgtggcctgt ggtaggggac cccgatcatc tctgagagtc ctaagacatg   1560
 gacttgaggt gtcagaaatg gctgtttctg agctacctgg taaccccaac gctgtctgga   1620
 cagtgcgtcg acacattgaa gatgagtttg atgcctacat cattgtgtct ttcgtgaatg   1680
 ccaccctagt gttgtccatt ggagaaactg tagaagaagt gactgactct gggttcctgg   1740
 ggaccacccc gaccttgtcc tgctccttat taggagatga tgccttggtg caggtctatc   1800
 cagatggcat tcggcacata cgagcagaca agagagtcaa tgagtggaag acccctggaa   1860
 agaaaacaat tgtgaagtgt gcagtgaacc agcgacaagt ggtgattgcc ctgacaggag   1920
 gagagctggt ctatttcgag atggatcctt caggacagct gaatgagtac acagaacgga   1980
 aggagatgtc agcagatgtg gtgtgcatga gtctggccaa tgtaccccct ggagagcagc   2040
 ggtctcgctt cctggctgtg gggcttgtgg acaacactgt cagaatcatc tccctggatc   2100
 cctcagactg tttgcaacct ctaagtatgc caggcctctc ccagcccagc ctgagtcctt   2160
 tgtgtatcgt ggaaatgggg tgggacttag aagcaggatg agctgggtga gaggggctcg   2220
 attggcttcc tatacctgaa tattgggcta cagaacggtg tgctgctgag gactgtcttg   2280
 gaccctgtca ctggggattt gtctgatact cgcactcggt aacctggggt cccgtcctgt   2340
 gaagctcttc cgagtccgaa tgcaaggcca ggaggcagta ttggccatgt caagccgctc   2400
 atggttgagc tattcttacc aatctcgctt cccatctcac cccactgtct tacgagacac   2460
 tggaatttgc atcgggtttt gcctcggaac agtgtcccga gggcattgtg gccatctcca   2520
 ccaacaccct acggattttg gcattagaga agctcggtgc tgtcttcaat caagtagcct   2580
 tcccactgca ggtacacacc caggaaaatt tgtcatccac cctgagagta acaaccttat   2640
 tatcattgaa acggaccaca atgcctacac tgaggccacg aaaagctcat gagaaagcag   2700
 cagatggcag aggaaatggt ggaagcagca tgggaggatg agcgggactt gggccgcaga   2760
 gatggcagca gcattccctc aatgaaaacc tccctgaatc catctttgga gctcccaagg   2820
 ctggcaatgg gcagttggcc tctgtgattc cgagtgatga atcccattca aggggaacac   2880
 acttggacct tgtccagctt ggaacagaat tagggcagct ttttagtgtg gctgtgtgca   2940
 ggttttccaa cactggtgat gactggtatg tgctggtggg tgtgcctaag gacctgatac   3000
 taaacccccg atctgtggca gggggcttcg tctatactta caagcttgtg aacaatgggg   3060
 aaaaactgga gtttttgcac aagactcctg tggaagaggt ccctgctgct attgccccat   3120
 tccaggggag ggtgttgatt ggtgtgggga agctgttgcg tcgtctatgg acctggggaa   3180
 agaaggaagt tacttccgaa aatgttgaga attaaggcat attgccaatt atatcttctg   3240
 gggatccaga ctattcggga catagggtaa ttgtatctga tgtccaagaa aagtttcatc   3300
 ctgggttccg ctacaagcgt aaattgaaaa ccaagcttat catctttgct gatgataccc   3360
 taccccccga tgggttcact acaggccagc ctcctgggac tatgacactg tgggctgggg   3420
 gcaggacaag tttnggccaa catatgtgtg ggtgaggctt cccaccttaa cacccattga   3480
 tgaagtaaga atgaggatcc tacaggaaac aaaagccctg ttgggacccg tgggcttgct   3540
 caaatggggg gcctcccaag aaaggcagag gtgatcattg aacttaccca tgtcggggga   3600
 gacgggtgct gtccttgcag aagaccacgg ttgatccctg ggaggcttca gaattcactt   3660
 gtcttattac caccttgttt tggaggaatt ggccatcctt gttccatttc acgtcccatg   3720
 aaggaccatt gacttctttc agcattgtgg aaaatgcacc tgcgggtctg aacatccccc   3780
 ttctctgtgg gggcggggac caccttcagc tttcgctcct tactactttc cctgtgaagg   3840
 aatgtgattg atgggagacc tctgtgaggc agttcaattc catgggaacc caacaaacaa   3900
 aaggaacgtc ttttgaagga actgggaccc gaacccccac cccgaagtgt tccaaggaaa   3960
 ttcgagggat attccgggac ccgttacggc ttctgaaacc ctccctttcc cggtggggct   4020
 tgcccagaga actgtgtgtt ttgtttcccc ccacccaccc atacaactgc accctggctt   4080
 tctgccatgt gggcaggaag ggtgaactgg aaaaattaaa gaactgccat ttatgaaaag   4140
 tccaacagct cctttccccc ctcagctcct tctccctgga atggactggg cttcccccct   4200
 caaattggca acttgagtat tggctacact tcctccccac ctggtacatg atacatgacc   4260
 ccccagggtt ccagtgtaga accttgagtc ccccaattcc ccaaagccat gccctgcatg   4320
 tgatatgtct tgactctcct gtcttacttt ttgcacacac cccttaattt ttaattgggt   4380
 tttcctgtaa atacagtttt tgtacaatgt ttatctctgt gggaggaagg aggcaggctg   4440
 tggtgggact gggtagggta tagtatcact cctgagttcc actgctctag aatctaacca   4500
 gaaatagaaa cctagttttt aaggtgactg gcatccatgt gtcttgttct ggagatgagg   4560
 atgtaggtgg gaggtttgaa cccaagttag agcaggaaga actgagtaga ctccttcctt   4620
 ccagataccg acttggactt gcggcactct gtggctcccc acccccaggt ctgtggtggt   4680
 ttctttgttt tttcctggtt ctttttgctg tgctgatgaa acatgacctc aataaccatg   4740
 tgtataccca cccctcttcc cactgggtat tgaggaaggg tggctgattc ttcctcctct   4800
 tctactctga ggatgttagt atggggattt tagcatgaat tccagctggg gagtcttaac   4860
 agatgcccct tttactgata gagcacctaa agcgatcttt ggctccatag gaccatagga   4920
 agggtcagta cagaagaacc tagatactgc cctgcccctg agaactgtgt atatgtgggg   4980
 cctgtctgca gcacccatct caggtgggtt ccagagggcc tttagggtat aatgagagcc   5040
 tgttaggtgg aagaggccca gttccagaaa tgttccagcc cacccctgag aattcctcct   5100
 gtttagttgt gtgggaagcc ctcgtcttcc aggctgtcct tgcgccttga acctggagaa   5160
 gtgagctcac tgttctcaat acttcacaaa tgtaaaactt tctttcgtct gcatgtgctc   5220
 agccatctaa attgagcaaa tgatctggtg agcactgggt tagaatcagg aatggtggaa   5280
 tacaatctga acctctcaga gcccagaaca gagggttcct gacactgtga cactgtctcc   5340
 tggaactaag tatctcttga atcatgactt ggttttagat cagtcaagag agacccaggt   5400
 tttgccagga atcgaatccc taaataacat gtttttttct cacttagctc atgaatttgc   5460
 atagtagaca gtagttctga attagatttt gaaaacctaa tttcagggct cattttttcc   5520
 ctgtgggccc taaaacccat tctattcaaa ttgtgtggat actggacatg gcagttcatc   5580
 tgagggaact tcagcgtagg ataacttgga ggcagctcct cggcctcttt tctaactcaa   5640
 gtttgactaa aatacataca ctccgtacag aaggtagggg gttatgtaag aaaggaaaac   5700
 ctaatctatg gaatcaggag ttgtcaccac cgagcttcct ctggaagtct gcccatcagc   5760
 ttgcttgttc tctgttaaga ggaagggcta ggacaaggat ttgggcttga atatgtggaa   5820
 aggaattttc atagttgttg ctgcaggacc tacaaaagtt taaaattaga ttggatgtga   5880
 ctcaatgaca agtcccatct gtgtaattgt taaggggacc tgattgactc ctgtggtttg   5940
 attgagcaac caggtaaata gagacctctc tccagctttg gcaaaaccca tcagaggctg   6000
 ctgcagaact cagacagagg gatctgccct tgggtttgct tccatcctgt tccattgcta   6060
 agcccttgtg acttggatcc taggactgaa aagtttttag ctgcctcagc tttcccctga   6120
 ccttactggc agaggttctg cagatgtttc ctttggaaga tctcttgcca agaatagcat   6180
 tcctttggag gaggggggtt ctagttggaa tgttgctttt cttggttagt gtaaatgtat   6240
 tgctagtgag acagctgccg gcgctggaaa aggctcgtct cacagggaga gtgctggtcc   6300
 ccagaatgtg tgctgttccc acgctgctgc ctttcttgag cttgttagag gaaagccaga   6360
 aaggcattca gatgggatca gtctggcttt caaatttttt ttaattccta agttctgttt   6420
 tattttttaa ttttttaaaa aaaattttat tagagacagt ctctctctct tgcctagctg   6480
 ggagtgcagt ggagtgatca tagctcactg aggcttgaac tcctgggctc gagcaatcca   6540
 cctcagcctc cagagtaggg gagactacag atgtgtgcca ccatactcag ctagttttta   6600
 aactttcgta gagacagggt ctccctgtgt tgcccaggct ggcctcgaac tcctgacctc   6660
 aaaaaatctt cctgccttgg cctcccagcg ctttgagagg ctgaggcagg aggatccctt   6720
 gagcccagga gtttgagacc agcctgggca acatgacaaa accccatctc tccaaaaata   6780
 caaaggttgg ccaggcagtg gtgagtgcac acttcgtagt cccagtaatt agggggctga   6840
 gacaggagga tcacttcagc ctatgagttt gaggctgcag tgagctgtga ttgcgccact   6900
 acactccagc ctggatgaca ggacgaaacc tgtctcaaaa acaccaaaaa acaaaaaccg   6960
 gtctcctggg gtcatggtag cacaaacgca catgactgag tgctcagggg ttctgaggct   7020
 tgtccgctga cctggggctc tggccctggg agatctgggg gacctgctgt ccctaatatg   7080
 tgatgccttt gaaaagaaag gggcatcatt cccaaaccca agagggcccc aaagagggca   7140
 ccgtgggggt gttccaggcc ttctgtgagg ccccagtgag atccctgtgg ctgtgccccc   7200
 atcacctcca cccactctgc cctcccacta ggtgcccaac ggatgaatca acgccttggc   7260
 agagttttcc agcagggcct tgcagagagt gtgtgtgacc tgtgtggcca ctgccttggg   7320
 gacgggtgag gagttagcct ggaacattcc cagcgtgggc attattgtcc tgttgcaagt   7380
 tcagggcaaa accaggaatc cagttttgtc gatccaattg agaaaacatt tcatgaacaa   7440
 ctacttgtgg catgcattgg cactcggaat aaagcgcact attgtcacta ggaaaaaaaa   7500
 aa                                                                  7502



      <210> 2091
      <211> 472
      <212> DNA
      <213> Homo sapiens


      <400> 2091
 aggagccaaa gcactgtcca gaaaggctgg aacttggcct cccagtgagc cggcttctgc     60
 ctcttgaagt catattcttc ccggagctcc tggagcaccc gcttggtgga cccggtggcc    120
 atccacactt cctgagccat ttcctcgtgg aagaggatct cccgctggaa cttctccaat    180
 ttctagacca ggtcttgtgc aatcttcttg agccagtcgc gggtctgact cacggcttcc    240
 agttgtcctg catcttgcca agcctccggt ccaggtccag acagtaggcg tcctcctcca    300
 tgcactcctg ctgaggcccc atcacggctc tctgcccagt gcaggaagag tgggggcctc    360
 agctgcagct gcaggacctc cgtctccagc cgtgcccttg ccccctgcag agaggcctgc    420
 tccctgagca cagattggat ttgggctctc actttttaac cggacgcgtg gg            472



      <210> 2092
      <211> 3572
      <212> DNA
      <213> Homo sapiens


      <400> 2092
 gacgctgaga ggcaggaggc actagggatc gtccgcagga ttgggactga tacagaggcc     60
 gccacggagc ccgccggagc caccgttcct gctgctgccg ccgctgcccg aatcggaacc    120
 gtcgggccgc agccgccggc aatgccgcga aggaagagga atgcaggcag tagttcagat    180
 ggaaccgaag attccgattt ttctacagat ctcgagcaca cagacagttc agaaagtgat    240
 ggcacatccc gacgatctgc tcgagtcacc cgctcctcag ccaggctaag ccagagttct    300
 caagattcca gtcctgttcg aaatctgcag tcttttggca ctgaggagcc ctgcttactc    360
 taccagaaga gtgacccgta gtcagcagca gcctacccca gtgacaccga aaaaataccc    420
 tcttcggcag actcgttcat ctggttcaga aactgagcaa gtggttgatt tttcagatag    480
 agaaactaaa aatacagctg atcatgatga gtcaccgcct cgaactccaa ctggaaatgc    540
 gccttcttct gagtctgaca tagacatctc cagccccaat gtatctcacg atgagagcat    600
 tgccaaggac atgtccctga aggactcagg cagtgatctc tctcatccgc cccaagcgcc    660
 gtcgcttcca tgaaagctac aacttcaata tgaagtgtcc tacaccaggc tgtaactctc    720
 taggacacct tacaggaaaa catgagagac atttctccat ctcaggatgc ccactgtatc    780
 ataacctctc aagctgacga atgcaaggtg agagcacaga acccgggata agcagataga    840
 agaaaggatg ctgtcttcac aggcaagatg acaacaacag gcattgcaac caggcaccag    900
 gcaccaacgg agaggcagct tcgatataag gaaaaagtgg ctgaactcaa gaagaaaaga    960
 aattctggac tgagcaaaga acagaaagag aaatatatgg aacacagaca gacctatggg   1020
 aacacacggg aacctctttt agaaaacctg acaagcgagt atgacttgga tcttttccga   1080
 agagcacaag cccgggcttc agaggatttg gagaagttaa ggctgcaagg ccaaatcaca   1140
 gagggaagca acatgattaa aacaattgct tttggccgct atgagcttga tacctggtat   1200
 cattctccat atcctgaaga atatgcacgg ctgggacgtc tctatatgtg tgaattctgt   1260
 ttaaaatata tgaagagcca aacgatactc cgccggcaca tggccaaatg tgtgtggaaa   1320
 cacccacctg gtgatgagat atatcgcaaa ggttcaatct ctgtgtttga agtggatggc   1380
 aagaaaaaca agatctactg ccaaaacctg tgcctgttgg ccaaactttt tctggaccac   1440
 aagacattat attatgatgt ggagcccttc ctgttctatg ttatgacaga ggcggacaac   1500
 actggctgtc acctgattgg atatttttct aaggaaaaga attcattcct caactacaac   1560
 gtctcctgta tccttactat gcctcagtac atgagacagg gctatggcaa gatgcttatt   1620
 gatttcagtt atttgctttc caaagtcgaa gaaaaagttg gctccccaga acgtccactc   1680
 tcagatctgg ggcttataag ctatcgcagt tactggaaag aagtacttct ccgctacctg   1740
 cataattttc aaggcaaaga gatttctatc aaagaaatca gtcaggagac ggctgtgaat   1800
 cctgtggaca ttgtcagcac tctgcaagcc cttcagatgc tcaaatactg gaagggaaaa   1860
 cacctagttt taaagagaca ggacctgatt gatgagtgga tagccaaaga ggccaaaagg   1920
 tccaactcca ataaaaccat ggatcccagc tgcttaaaat ggacccctcc caagggcact   1980
 taaagtgacc tgtcattccg agccagcgaa ccccagcagt aggaatccgt accctaggga   2040
 tctgtctgtc atttctctgt tgctcttgtg attggcaagt acagtatcct ttgggaaggc   2100
 catccccctc aggactgtcc tggctccgac ctttgtgtac actgcagacg ctggttctga   2160
 ggaactgttg tttcggcctc agtgaggttg cctggatggg atctgtatta gacttgagtg   2220
 caggtctctc agcactgacc caaggagttc tgttatggta ctgtacctgt ccagtcactg   2280
 gttctctcct catgtcctct cgccccatga ggttgtgttg tgtcttctaa gcgtggtact   2340
 agtgcttgcc acctggtcac cagacctcca aatatggctg ccaccaccag gacctttcca   2400
 gttactcctt atatgtgtgt tctatggagg ggcagggaaa aggtggcact tgtgagtgtg   2460
 tgtggattgg cagggggtcc attcactttg ggttccatct tgctttaaat ttcttcattt   2520
 tgattaagag acctcttttt gatctgtatt gggctaacca gagccaaata cttttgaaga   2580
 gtttcccagg gactagtcat ggtaatagca tataattgat ctgaatgaga tggagagaag   2640
 aatgaagggg tggtggttct gggtttgatt tgagttcacc tgtgggcagt gggcagtggg   2700
 cagtgtcttg gtgaaaggga acggatacta ctttttgcct caccgtaaag tactcactag   2760
 taaatatttc cttctctctt tactcccact ttttacgttt gcaggtgcca aagtaatgtc   2820
 cacttttccc tttcatgctg catattaact ggttaattat actgcagaaa ccttttcacc   2880
 tccactagtc tgatacagta catctgtact tccatatacc ttgcactgat tttgtctgag   2940
 tgccctggga gaagtagaaa atgattgaaa gtgacttccg tatctcagcc catgactcag   3000
 caaggcagaa tggccacccc tgccaaagtt tgcttctctt ttcaacagtg cctcaccctc   3060
 cctctaggat taaagtgctt ctgcccttcc acgaactcct cctccatttc ctttttggga   3120
 tttgtcacca tccttctatt ctctggtctt ctatttttgg tgttgttcaa gtgaaggaag   3180
 agatgttccc tctaatttct ctctagccca ttataacctg ctatcttggg gcaacttttg   3240
 atgtatgaca tgtcaccctt cccaacttgg tctcctccaa catgctgtct tcatgtggag   3300
 ccctcaccac aatccctgac tccggtcatt tgtgcctttc tcttgtcatc tctgtacact   3360
 acttatattc actgtgggtt gggggagcta attttaagca tgttcagtgg cagctcccct   3420
 ccagtttcag tgtcactgtt aaaatttatc aaaaagcaac ttcactaggg gttttcttaa   3480
 gggataaagg ccttttacag aagctaaacc cttccccaca tgtggtagaa tgtgctcttc   3540
 tatatctact cctcaataaa gcatgttctc tg                                 3572



      <210> 2093
      <211> 719
      <212> DNA
      <213> Homo sapiens


      <400> 2093
 atcgagagcc tatcgatgtg gggcttttct tacagattgg gaaatggtgg tggggaaacc     60
 gaacaattta tgtttgctct tgaaactgtt ttaggtgtgg cctgaagtca ctgatcctga    120
 gaagttcgtg tatgaagatg tggctatcgc agcatacctg ctgattctat gggaagaaga    180
 aagggctgag aggggactaa ctgccaggca gtcctttgtg gacctgggat gtggaaatgg    240
 cctcctggtc cacatcctga gcagtgaggg gcatccaggc agagggattg atgtccgaag    300
 aagaaaaatc tgggacatgt atggaccaca aactcagtta gaggaagatg caatcacacc    360
 caatgataag acccttttcc ctgatgttga ttggttaatc ggtaaccatt ctgatgaact    420
 cacaccatgg atacctgtca ttgcagccag gtcttcctac aattgccgct tctttgtcct    480
 cccctgctgc ttctttgact tcattggaag atactcccgg aggcagagta agaagactca    540
 gtaccgggaa taccttgact tcattaaaga agtgggcttc acctgtgggt ttcacgtgga    600
 cgaagactgc ctcaggattc cttcaaccac aagagtctgt ctcgttggaa aatccagaac    660
 atacccttac tccatagaag cttccgtgga tgaaaagagg actcagtaca ttaagagcc     719



      <210> 2094
      <211> 429
      <212> DNA
      <213> Homo sapiens


      <400> 2094
 atggcagtat tcaagggctc acctgatgta gggtgcctta ccagctgccc aggctgcagc     60
 ttccaaagca cagcccactc tttcccaagg ctgtacctct gtcctgctgt tcctgctacc    120
 ctgaatgcca ttcctctctt tgcatacctg acaaattcct attcatcctt caagaaccaa    180
 cttcttctgg aagccttgct tgacccccaa cccttaacca caggtccctt cctcatactg    240
 ctcctctcac ctgtgagcac agaccaggcc aacaccacca ctgctgagat ccacagccag    300
 ctcaccccac ggctaaatct caccatccta tcatcccagg gggcaagtct tcagcagagg    360
 gtcacgtacc atcgaaatca caagtacggc cagacccacc cccaaaaggc cgaaatagtt    420
 gtcggctga                                                            429



      <210> 2095
      <211> 361
      <212> DNA
      <213> Homo sapiens


      <400> 2095
 ggcacgagct ggaagaatta attctggaat atttcttaaa cttgcttgag ttgtgtaagg     60
 tctggctgct gggctccctg aaaccttgca catatcttac tgtatgactg tatttcgttt    120
 tgagtctctg gattctgggg tttggacaga tgaccatagt gaggcctgca gaaatatgca    180
 tgtcctcagt gtttggactg ccagctgcaa ggcagagcca aacccaatat ggccccatca    240
 tccctggctc agctgtgcta cctggccatg ctggaagggg tttgatcttc caggaatttg    300
 cttcacagct ctttcctgtc ccaagatcta tgcctgatgt gtaaattcag gacccaaaag    360
 g                                                                    361



      <210> 2096
      <211> 1608
      <212> DNA
      <213> Homo sapiens


      <400> 2096
 cccatgtatc ttttcctgtg tcctccactg gcccttgtcc agtgcgccct gaaggaccca     60
 cgcagcaagt actcactagg aggacgaaca accctgatta taactttaca gggctcagga    120
 aagaaaaaca acatccctca tccatcttct ctttcagaaa gggtcatgac agccaaggat    180
 ggctttgtaa gcagatgcca tctgctgatg cagccgaagc agcagaaatg gtccctgatg    240
 tatcccatgg aaggagaggt gctggagaat ggttgctggc ccactctaca ggacagcttg    300
 ctatgcacag cgctggtgga caagctcttg gtgtttctgg gcaggtgttt ctgcacagca    360
 gttgaggtgg tgatgctggt gacatgcagg acagcagctg ctgtttctgc ttttctcatc    420
 gtgggcaggg ttagcagccc cgtgtgcaga gccgtgagcg tgcagccctg gactctgacc    480
 gctgaccaca ctcccggcag atactgcctc aagctcgtct gccggcagct ctgcttgtgt    540
 ccatcgagca caccactgac agaagtcttc tgtagtaaag aagccttctt tatcatccta    600
 gattgtagca atctgcccca tgccctgtta cctgtggact cacccaaggg cttgagtaaa    660
 tgcagcaatc caagagagaa agcaaggagg aagctgcagg gccattacca cgtggcctct    720
 gaagtcagct ttgtgccagt tagaaggttc cccaagggtg aaattggtgc caaccaaccc    780
 ggcacgcaca ggaagtttta ccaccttact cactatcgcc aaaacttgaa gcagccagat    840
 gtccctcacg ggcgaattgt gtttgatgat aaagacatta ccgactggca gacagcgaaa    900
 atcatgcgcg aagcggtggc gattgtcccg gaagggcgtc gcgtcttctc gcggatgacg    960
 gtggaagaga acctggcgat gggcggtttt tttgctgaac gcgaccagtt ccaggagcgc   1020
 ataaagtggg tgtatgagct gtttccacgt ctgcatgagc gccgtattca gcgggcgggc   1080
 accatgtccg gcggtgaaca gcagatgctg gcgattggtc gtgcgctgat gagcaacccg   1140
 cgtttgctac tgcttgatga gccatcgctc ggtcttgcgc cgattatcat ccagcaaatt   1200
 ttcgacacca tcgagcagct gcgcgagcag gggatgacta tctttctcgt cgagcagaac   1260
 gccaaccagg cgctaaagct ggcggatcgc ggctacgtgc tggaaaacgg ccatgtagtg   1320
 ctttccgata ctggtgatgc gctgctggcg aatgaagcgg tgagaagggg cgatgaactg   1380
 accgaggacc ggtcccgttc gctggacggg gaactgatcc gatctttacc ctgtggtgcc   1440
 tcctatggcg ggctgtccct ccggccgtgg agccggggcc atattcccca gtcccatcaa   1500
 tcatcagagt cagtcagagt catgttcata aacaccagta agggtgcatc catcatcagc   1560
 agttcagcaa caatgccagg cccattgcca aagcatttgg gcccatag                1608



      <210> 2097
      <211> 789
      <212> DNA
      <213> Homo sapiens


      <400> 2097
 atgcatgttc aggggaaggc agccatcctt ggaagacact tttccatcag ttctcttctc     60
 ccaggagctc tattgctgct caccgttatc aaaggccaca ctcacccaga ggagaagagt    120
 ccaggtgccc atgagaaagc tgtgacgggt gaacccaagt gcctcggggc cctgccgtac    180
 tgtgattccg gaggaaagaa ggccacgaag aagaaagatg ctggggaaat gagatcaaga    240
 ataaaggatg gtgtcctcgt actaaaatgt atcagtctgc aagtcggcct tgcctcctgg    300
 attgtgagtt ggctgaggac cgaggccaca ggatacacct ttgctctcct gcctcctggc    360
 acccatcaca cggagcagac ccccagtaaa catgagcaaa atggagctga attgttctgc    420
 aactgcgtgt cttgctttga agacccctgt ccctgccagg tgcctgggac acagccagga    480
 aaccgcctct ctgaggagca ccaggcctct tcccaggctg acgtgaccaa ctcgtctgcc    540
 cctaaacaac cgcacccacc accggcacca tgcaagggtg tctgttcaca ttgctgagct    600
 gggcgagatc gtctggtcag tcattacata aaacaggagc ccagtgacct ttgcgaagta    660
 cacaaggtgg aagtcatgag cgaaagagat catgaacgct tcaaatatgg ctacggagtt    720
 ataagcgtca tcaccaactc actgaagatt aaggaatctg ggaacaaatt agcctgttgt    780
 agacagtga                                                            789



      <210> 2098
      <211> 753
      <212> DNA
      <213> Homo sapiens


      <400> 2098
 caacctctgc ctcctgggtt caagcgattc tcctgcctca gcctcccgag taggtgggat     60
 tacaggcgtg cgccaccaca cctggctaat ttttgaggaa tacatttttt aagccatctg    120
 gtctgtggta gttcatgaca gtggcctgag caacctcagc cccacctgag gtggccccag    180
 ggagagcacc tggcagtctt tgccctttgc tgcccccagc actaggctac catcatgacg    240
 tttctgggtt tctgacattt gccagtttgc ccacaagatg gcaggcaccg cccagctgtt    300
 ggggttgaag cagctcatag gccttgagtt gctgacggcc cagtgcggtc agatcactgg    360
 ctacagggac agaagggagg agttactacc cccaaggttt ctggctacag ggcccccatc    420
 ctgtcacccg ccttcccaaa cagtaccctg attcctcaac catggccaca tcttaagcca    480
 cctggggcca gtgctggggc catcctaggg ccaggtgacc ttggtggatg tggcctcctg    540
 gctttggtgg ttcctgggct cccaggtgat cgtagtgagc ccttggggtt gaagagcaat    600
 gctctcccac cccggggaca cacatgcctc ctgagggaag gaccgtccct tggaatcgag    660
 gaaaacccca ccggtcctaa aactaccgtt agggcaccgt cttgcacatt gctgtagtta    720
 accttccagg cctcttggtt tccattgaaa ctg                                 753



      <210> 2099
      <211> 8294
      <212> DNA
      <213> Homo sapiens


      <400> 2099
 atgtggggca gcgatcgcct ggcgggtgct gggggaggcg gggcggcagt gactgtggcc     60
 ttcaccaacg ctcgcgactg cttcctccac ctgccgcggc gtctcgtggc ccagctgcat    120
 ctgctgcaga atcaagctat agaagtggtc tggagtcacc agcctgcatt cttgagctgg    180
 gtggaaggca ggcattttag tgatcaaggt gaaaatgtgg ctgaaattaa cagacaagtt    240
 ggtcaaaaac ttggactctc aaatggggga caggagctgc atgctgtttc ccttgaacaa    300
 catcttctag atcaaattcg aatagttttt ccaaaagcca tttttcctgt ttgggttgat    360
 caacaaacgt acatatttat ccaaattgtt gcactaatac cagctgcctc ttatggaagg    420
 ctggaaactg acaccaaact ccttattcag ccaaagacac gccgagccaa agagaataca    480
 ttttcaaaag ctgatgctga atataaaaaa cttcatagtt atggaagaga ccagaaagga    540
 atgatgaaag aacttcaaac caagcaactt cagtcaaata ctgtgggaat cactgaatct    600
 aatgaaaacg agtcagagat tccagttgac tcatcatcag tagcaagttt atggactatg    660
 ataggaagca ttttttcctt tcaatctgag aagaaacaag agacatcttg gggtttaact    720
 gaaatcaatg cattcaaaaa tatgcagtca aaggttgttc ctctagacaa tattttcaga    780
 gtatgcaaat ctcaacctcc tagtatatat aacgcgtcag caacctctgt ttttcataaa    840
 cactgtgcca ttcatgtatt tccatgggac caggaatatt ttgatgtaga gcccagcttt    900
 actgtgacat atggaaagct agttaagcta ctttctccaa agcaacagca aagtaaaaca    960
 aaacaaaatg tgttatcacc tgaaaaagag aagcagatgt cagagccact agatcaaaaa   1020
 aaaattaggt cagatcataa tgaagaagat gagaaggcct gtgtgctaca agtagtctgg   1080
 aatggacttg aagaattgaa caatgccatc aaatatacca aaaatgtaga agttctccat   1140
 cttgggaaag tctggcctaa agacataagt gaagaagaca taaaaactgt attttattca   1200
 tggctacagc agtctactac caccatgctt cctttggtaa tatcagagga agaatttatt   1260
 aagctggaaa ctaaagatgg tccttctaga tcctatggta aaagaagaaa acaaggagtg   1320
 aattccttag gcgtatcctc cttggagcac atcactcaca gcctcctggg acgccctttg   1380
 tctcggcagc tgatgtctct tgttgcagga cttaggaatg gagctctttt actcacagga   1440
 ggaaagggaa gtggaaaatc aactttagcc aaagcaatct gtaaagaagc atttgacaaa   1500
 ctggatgccc atgtggagag agttgactgt aaagctttac gaggaaaaag gcttgaaaac   1560
 atacaaaaaa ccctagaggt ggctttctca gaggcagtgt ggatgcagcc atctgttgtc   1620
 ctgctggatg accttgacct cattgctgga ctgcctgctg tcccggaaca tgagcacagt   1680
 cctgatgcgg tgcagagcca gcggcttgct catgctttga atgatatgat aaaagagttt   1740
 atctccatgg gaagtttggt tgcactgatt gccacaagtc agtctcagca atctctacat   1800
 cctttacttg tttctgctca aggagttcac atatttcagt gcgtccaaca cattcagcct   1860
 cctaatcagg aacaaagatg tgaaattctg tgtaatgtaa taaaaaataa attggactgt   1920
 gatataaaca agttcaccga tcttgacctg cagcatgtag ctaaagaaac tggcgggttt   1980
 gtggctagag attttacagt acttgtggat cgagccatac attctcgact ctctcgtcag   2040
 agtatatcca ccagagaaaa attagtttta acaacattgg acttccaaaa ggctctccgc   2100
 ggatttcttc ctgcgtcttt gcgaagtgtc aacctgcata aacctagaga cctgggttgg   2160
 gacaagattg gtgggttaca tgaagttagg cagatactca tggatactat ccagttacct   2220
 gccaagtatc cagaattatt tgcaaacttg cccatacgac aaagaacagg aatactgttg   2280
 tatggtccgc ctggaacagg aaaaacctta ctagctgggg taattgcacg agagagtaga   2340
 atgaatttta taagtgtcaa ggggccagag ttactcagca aatacattgg agcaagtgaa   2400
 caagctgttc gggatatttt tattagagca caggctgcaa agccctgcat tcttttcttt   2460
 gatgaatttg aatccattgc tcctcggcgg ggtcatgata atacaggagt tacagaccga   2520
 gtagttaacc agttgctgac tcagttggat ggagtagaag gcttacaggg tgtttatgta   2580
 ttggctgcta ctagtcgccc tgacttgatt gaccctgccc tgcttaggcc tggtcgacta   2640
 gataaatgtg tatactgtcc tcctcctgat caggatggaa gttccagctc tgatagtgac   2700
 ctaagtctgt cttcaatggt ctttcttaac catagcagtg gctctgacga ttcagctgga   2760
 gatggagaat gtggcttaga tcagtccctt gtttctttag agatgtccga gatccttcca   2820
 gatgaatcaa aattcaatat gtaccggctc tactttggaa gctcttatga atcagaactt   2880
 ggaaatggaa cctcttctga tttggaggac gaatccatga accaaccagg accaatcaaa   2940
 accagactgg ctattagtca gtcacattta atgactgcac ttggtcacac aagaccatcc   3000
 attagtgaag atgactggaa gaattttgct gagctatatg aaagctttca aaatccaaag   3060
 aggagaaaaa atcaaagtgg aacaatgttt cgacctggac agaaattctt tgatgaaatc   3120
 actgagctga catacctgcc ctcttttcac cataaagctg ctcctcacca ggccgagcca   3180
 ggtcccaatt cttcctcagc ctctgctccc ccaccctata atccttttat cacctcctct   3240
 cctcacactc agtccggctt acagtttcgt tctgtgacta gccctccccc atctgcccaa   3300
 caatttcctc ttaaagaggt ggctggagct aaaggcatag tcaagacagc tttagagact   3360
 gctcccacac tagctctccc tgtctcatcc caaccctttt cattacacac agccgaagtg   3420
 cagggctgtg cagtcggaat tcttacacaa ggaccgggac catgccctgt agcctttttg   3480
 tccaaacaac ttgaccttac tgttttaggc tcgccatcat gtctccatgc ggtagcttcc   3540
 gctgccctaa tacttttaga ggccctcaaa atcacaaact atgctcaact cactctctac   3600
 agctctcaca acttccaaaa tctattttct ttctcacacc tgacgcatat actttctgct   3660
 ccccggctcc ttcagctgta ttcactcttt gttgagtctc ccacaattac cattcttcct   3720
 ggcccagact tcaatctggc ctcccacatt attctggata ccacacctga ccctgatgat   3780
 tgtatgtctc tgatctacct gacattcacc ccatttcccc atatttcctt cttttctgtt   3840
 cctcatgttg atcacatttg gtttactgac ggcagttcca ccaggcctga tcgccactca   3900
 ccagcaaagg caggctatgc tatagaatct tccacatcca tcattgaggc tactgctctg   3960
 cccccctcca ctacctctca gcaagccgaa ctgattgcct taactcgggc cttcactctt   4020
 gcaaagggac tacacgtcaa tatttatact gactctaaat atgccttcca tatcttgcac   4080
 caccatgctg ttatatgggc tgaaagaggt ttcctcacta cgcaagggtc ctccatcatt   4140
 aatgcctctt taataaaaac tcttctcaag gctgctttac ttccaaagga agctggagtc   4200
 acacactgca agggccacca aaaggcgtca gatcccatta ctctaggaaa tgcttatgct   4260
 gataagggtg tccgctgtgc tcctgatcca gcgaggcgcc cattgccgct cccaattggg   4320
 ctaaaggctt gccattgttc ctgcacggct aaaattggag gaaaataccg ggcacttgtc   4380
 ggccagttaa aaacgattag tgtggccacc ggacttaaga ctcaggacag gacgatagat   4440
 ggttcctccc aggtgattga ggaaaaaaac cacaatgggt attcagtaat tgatacgggg   4500
 actcttgtgg aagcagagtt agaaaaattg cctaataact ggtctcctca aacgtgtgag   4560
 ctgtttgcac tcagccaagc cttaaagtac ttacagaatc aaaagactat ctcaatcctg   4620
 attcaaaagg aacccagccc agctctagga ctcacccctg agcgcaaagg caatgttggg   4680
 catgctggta aaggaccact agaatccagc agcccagacc cctttctttg tggtcaagaa   4740
 aggcgggaaa aggggtgcag gactgctaca tcggtaagca taactaatcc gataaacaga   4800
 ggtccatggg tggttacgca ccctggaaag gaactcaccc ctgagcacaa aggcaatgtt   4860
 gggcacgctg ggagagacat tctagcaaaa gcaggggcca ttatacacct gaacatagga   4920
 gaaggaacac ccgtttgttg tcccctgctt gaggaaggaa ttaatcctga agtctgggca   4980
 acagaaggac aatatggacg agcaaagaat gcccgtcctg ttcaagttaa actaaaggat   5040
 tccacctcct ttccctacca aaggcagtac cccctcagac ccaaggccca acaaggactc   5100
 caaaagattg ttaaggacct aaaagcccaa ggcctagtaa aaccatgcag taacccctgc   5160
 agtactccaa ttttaggagt acagaaaccc aacagacagt ggagaaacct tgtgccatca   5220
 agccacccaa gcgctcttca atttcctcgc tacctgtggc tacatggttt ccaaaccaaa   5280
 ggctcaactc tgctcacagc aggttactta gggctaaaat tatccaaagg caccagggcc   5340
 ctcagtgagg aacacatcca gcctatactg gcttatcctc atcccaaaac cctaaagcaa   5400
 ctaaggggat tccttggcgt aataggtttc tgccgaaaat ggattcccag gtatggcgaa   5460
 atagccaggt cattaaatac actaattaag gaaactcaga aagccaatac ccatttagta   5520
 agatggacaa ctgaagtaga agtggctttc caggccctaa cccaagcccc agtgttaagt   5580
 ttgccaacag ggcaagactt ttcttcatat gtcacagaaa aaacaggaat agctctagga   5640
 gtccttacac agatccgagg gatgagcttg caacctgtgg catacctgac taaggaaatt   5700
 gatgtagtgg caaagggttg gcctcattgt ttacgggtag tggcagcagt agtagtctta   5760
 gtatctgaag cagttaaact aatacaggga agagatctta ctgtgtggac atctcatgat   5820
 gtgaatggca tactcactgc taaaggagac ttgtggctgt cagacaacca tttacttaaa   5880
 tatcaggctc tattacttga agggccagtg ctgcgactgt gcacttgtgc aactcttaac   5940
 ccagccacat ttcttccaga caataaagaa aagatagaac ataactgtca gcaagtaatt   6000
 gttcaaacct acgctgctca aggggatcct ttagaggttc ccttgactga tcctgacctc   6060
 accttatgta ctgatggaag ttcctttgta gaaaaaggac ttcgaaaagt ggggtatgca   6120
 gtagtcagtg ataatggaat acttgaaagt aatcccctca ctccaggaac tagtgctcag   6180
 ctagcagaac taatagccct cacttgggca ctagaattag gagaagaaaa aagggcaaat   6240
 atatatacag actctaaata tgcttaccta gtcctccatg cccatgcagc aatatggaaa   6300
 gaaagggaat tcctaacttc tgagagaaca cctatcaaac atcaggaagc cattaggaaa   6360
 ttattattgg ctgtacagaa acctaaagag gtggcagtct tacactgccg gggtcatcag   6420
 aaaggaaagg aaagggaaat agaagagaac tgccaagcag atattgaagc caaaagagct   6480
 gcaaggcagg accctccatt agaaatgctt ataaaacaac ccctagtata gggtaatccc   6540
 ttccgggaaa ccaagcccca gtactcagca ggagaaacag aatggggaac ctcacgagga   6600
 catagtttcc tcccctcagg atggctagcc accgaacaag gaaaaatacc tttgcctgca   6660
 gctaaccaat ggaaattact taaaaccact caccaaaact ttcacttatg cattgatagc   6720
 acccatcaga tggccaaatt gttatttact ggaccaggac ttttcaaaac tctcaagcag   6780
 atagttgggg cctgtgaagt gtgccagaga aataatcccc tgccttatcg ccaagctcct   6840
 tcaggagaac aaagaacagg ccattaccct ggagaagact ggcaactgat tttacccaca   6900
 agcccaaacc tcagggattt cagtatctac tagtctgggt agatactttc acgggttggg   6960
 cagaggcctt cccctgtagg acagaaaagg cccaagaggt aataaaggca ctagttcatg   7020
 aaataattcc cagattcgga cttccccgag gcttacagag tgacaatagc cctgctttcc   7080
 aggccacagt aacccaggga gtatcccagg cgttaggtat acgatatcac ttacactgcg   7140
 cctgaaggcc acagtcctca gggaaggtcg agaaaatgaa tgaaacactc aaaggacatc   7200
 taaaaaagca aacccaggaa acccacctca catggcctgt tctgttgcct atagccttaa   7260
 aaagaatctg caactttccc caaaaagcag gacttagccc atacgaaatg ctgtatggaa   7320
 ggcccttcat aaccaatgac cttgtgcttg acccaagaca gccaacttag ttgcagacat   7380
 cacctcctta gccaaatatc aacaagttct taaaacatta caaggaacct atccctgaga   7440
 agagggaaaa gaactattcc acccttgtga catggtatta gtcaagtccc ttccctctaa   7500
 ttccccatcc ctaggataca tcctggggga agggaccctt acccagttca tttttatttt   7560
 accccaattg cgggtttaaa gtggctggag tggagtcttg gatacatcac acttgagtca   7620
 aatcctggat actgccaaag gaacctgaaa atccaggaga caacgctagc tattcctgtg   7680
 aacctctaga ggatttgcgc ctgctcttca aacaacaacc aggaggaaaa atcgaagctg   7740
 taaaactaca aatggagccc aagatgcagt ccaagactaa gatctaccgc agacccctgg   7800
 accggcctgt tagcccacga tctgatgtta atgacatcaa aggcacccct cctgaggaaa   7860
 tctcagctgc acaacctcta ctacgcccca attcagcagg aagcagttag agcggtcgtc   7920
 ggccaacctc cccaacagca cttaggtttt cctgttgaga tgggggactg agagacagga   7980
 ctagctggat ttcctaggct gattaagaat ccctaagcct agctgggaag gtgaccacat   8040
 ccacctttaa acacggggct tgcaacttag ctcacacctg accaatcaga gagctcacta   8100
 aaatgctaat taggcaaaga caggaggtaa agaaatagcc aatcatttat tgcctgagag   8160
 cacagcagga gggacaatga tcgggatata aacccaagtt ttcgagccgg caacggcaac   8220
 cccctttggg tcccctccct ttgtatggga gctctgtttt catgctattt cactctatta   8280
 aatcttgcaa ctgc                                                     8294



      <210> 2100
      <211> 1113
      <212> DNA
      <213> Homo sapiens


      <400> 2100
 ctcatttctg aaaaattcta agtcatgaga agataagccc tatcctttct tacaaggatt     60
 ggatttcctg gggtgaccac tgtggtgtgg tggaagccag cggcttcttt ccaggttcat    120
 aaaggccatc ataacaactt ccaggcttca tggtgtggac agggatccag gagagctgag    180
 tggatgtgtg aagtttctga tagattctgt catcattccc aaaggaatgt agtttcctcc    240
 agctcaatca tttgaagcaa tacacattgc caaatctgac tgtaacctga cattttagac    300
 ctattggaga aataggaaga aagcccctcc agtggaagga ctggacttgg aagaagttct    360
 gcaggaaggc gcatgcaatt ggatagctgt tcatgagtga aacgtgggga acattgctat    420
 gaaattgtaa ggtttgcact tcatttttcg tagcttaaaa attgctctgt tctggctgtt    480
 gaaaacactt ggtgtgaggt ttgaatgagg attatataat cattctagta ttcataggaa    540
 aatgattact gctctcctat ttgtaaaaca aaagaaataa ctttcggaaa cagtatttta    600
 gacatgagga aattgtttgt attaggcatt ttgatctaac agaatcagct aaggataagt    660
 ggatcctggc tttacacatt tctttgacca aacccagctg gcaacttgaa gttgttactg    720
 tgtggcttcc agattgccta gaggtgaatc ctaccaacat cactgttttt tttgttttgt    780
 tttgtttttt ttgtatgttt ttgagacaga gtcttgctgc tatccccagg gctggagtgc    840
 agtggcacgt tcttggcttt actgcaacct cagcctccgg ggtttcaagg gattctcctg    900
 cctcagcctc ctaagtaact gggattatag gtgcactcca ctacgttcag ctaattttgt    960
 atttttagta gagacagggt ttcaccatgt tggcccacgt cggtctcaaa ctcctgacct   1020
 caaggtgatc caccctcctt ggcctcccaa agtgctgggg attacaaggg tgtgagccac   1080
 catgcctggg cccagacctc ttgatatata tca                                1113



      <210> 2101
      <211> 888
      <212> DNA
      <213> Homo sapiens


      <400> 2101
 atgaggcctg tggaccccga tgggactgag cattcactct tctgcccact gacagcttta     60
 cggggaatgg tgaactcgag aatccagaag tctccaggga agcccagtgt gtgcgacgtg    120
 cctcttccta tctcccctgg gcagtcttcc cagctccatg gaaaagtctt tggtcagctg    180
 aacgcaggca aggctgctga attcctgaag tccccgcctg accaccaggc ccaggcagca    240
 tccacctctg ggccacagaa gacgaccctg agcaaacgtg gcttaaggct ccaaccctgt    300
 caactccact cagccccaca ctccttccag ctccttccac tcacacaaaa gagcacctgg    360
 gacttgagag gcagcgcgcc tctccacgca gcacagactt cactttccga gttctcctgc    420
 caccgacctg acgtggaaga cacacttggc acaaaaggac cagacaaaac ccagtgccag    480
 tcagagaatt ccacacggcc acagtacagt ccagaaacca gccagaacca gcccgtgggc    540
 aagggaacag acctgaaagt cacaaagctt ggcgtgccct ccctgatggc ccaagatggg    600
 gtcaactact cggtgaaaac agaggcccat tccacaggca ccactgctga gcctctgagt    660
 tcccaggaca gggctgtccg aggacacaac actgacagcc atgtgcagac ccccgacctg    720
 ggcgaggata ccgccctctg agactcagtc gcctgtctac aaaaaaggaa aagataccac    780
 attaccgtga ccatctagtc taatgaaaat gccaccagga tcaaagacca taacgcaaag    840
 ccctctgttt gcaccttagt ccgaacaagc acccaggata cactcgct                 888



      <210> 2102
      <211> 955
      <212> DNA
      <213> Homo sapiens


      <400> 2102
 tttcgtcttt ccagacaaag acaagtgaca agaattttag gtttaaaaag caaccagatt     60
 catctcagca gcttttgtag ttttaaataa gcaaggagtt tctccagcga aacttcctca    120
 cacctcttgg tcttggtctc ttcagacact ttccttcctg ttctctggag atcttgcaga    180
 aaagagcctg cagtgtttcc cttgctcagc catgctcctg gagcttatcc cactgctggg    240
 gatacatttt gtcctgagaa ctgccagagc ccagtcagtg acccagcctg acatccacat    300
 cactgtctct gaaggagcct cactggagtt gagatgtaac tattcctatg gggcaacacc    360
 ttatctcttc tggatggaaa gaactgttga agaagctttt atacttcttg tttgcttgaa    420
 gccttggagg gtagcaagta gtctggagaa aaaggagaag gaggatgaat ctttccagct    480
 gctacttggc tcacgctata atgtattaaa gggtagcagg ggtgagacga gtgaaggtgg    540
 agcagagtcc ttcagttccc agtctccagg agagaaccag ctctactctg agatgcagtt    600
 tttctacctc tgtgaacaac gtgcagtggt tccaacagaa tcctgggttg gcctcatcaa    660
 tctgtttttc atggcttcat ggatgaagca cagtggaaag ttatggtcaa aaagaaactc    720
 tgaggagctc tgtggtaccc tacacatcac agccgcccaa ctgaaagact caggcacgta    780
 cttctgtgca gttgaggcac agttctccca ggaaatctgc agcctggatc cgaactgcag    840
 ctgggcctgc agccccaacc ccttccgtga gagaggcatg ttgcccccac agtatcactt    900
 gcacagcttc gggttttctg attgacgctg cgcttttatc tctgctaaaa ctata         955



      <210> 2103
      <211> 3122
      <212> DNA
      <213> Homo sapiens


      <400> 2103
 cgtccccggc gcataaggct tcgcgggcgc accaggatac ccgaagtcac ctcctgtagc     60
 ttccccagga gctgcggtgc cttctctggt gtctttttct gcggggctca cccagaagcc    120
 tttccccagt gatgggggcg ttgtcctctt taacaaagtg ctggtgaacg acggggatgt    180
 ttacaacccc agcaccgggg tcttcacggc tccttatgat gggcgctacc tgatcacggc    240
 caccctcacc cccgagagag acgcctacgt ggaagcagtg ctgtcggtct ccaacgccag    300
 cgtggcccag ctgcataccg ctgggtacag gagagagttc ctggaatacc accgccctcc    360
 aggagctttg catacctgcg ggggcccggg ggcattccac ctcatcgtgc acctgaaggc    420
 gggagatgca gtcaacgtcg tggtgactgg gggcaagctg gctcacacag actttgatga    480
 aatgtactcc acatttagtg gggttttctt atatcctttc ctttcccacc tctaaggtgg    540
 ctggggagat gtcaggggaa agatagatag ttgtaaaaac tctaaagctt taatatattc    600
 ggtttgtatg taatggaagc acggggctag agtttccaca taggccccaa cataaaggcc    660
 ttccctcgct gttgaggcca ccatgcctta ctgcatccag ccaggctgca gggagtgagg    720
 cacacggtga acatggccac tgacttttct gccactctaa ctggacaact ggaagacttg    780
 gaaaggcctc cacctgtatc tacactctga gggccctgga ctgggcctga gcttgccaca    840
 gaggctccgt ctgactgtgg gctgggagga gggaggcagg ggagagccgg tcacggtggc    900
 tggtctttac tgcagggcag cactgtggcc agctgtctgt ctttacactg catgcagaag    960
 tttaaacact gaagtgccga agtggcccgt gccgccgcac agagaccccg actttagttt   1020
 gggctgttcc acgcttggct caccattgcc gcctgggact taacctgctc aggcgggcct   1080
 tcgcccagct gcaaataggg atgcgttaga gactgttccc aaagcttgtt gggctcctta   1140
 aatggcatgt acaatttaag tgcaaagaca gggagtgtca ataaagatgg aaagccattt   1200
 ccagttaact tttgttaatt taagtgtggt cccttacaga tcgggagttg ttgctaaaaa   1260
 gcaaactgaa gaaatgtttt gtttcaaaaa gggctacaga aagtaacctt gagtaaaatt   1320
 aatctcagct acaaaactgt tacccctccg catccaagct atacacttgg gttttgtttc   1380
 tggcttgtga agacggacca gatgtgcacg gaggtcacgg ccccatgtca tctgcagctg   1440
 gagcggctcc tctggggatg ctgcactcag atcccacagc agctgcccag gctaacttga   1500
 tccctgctgc ttcactgcac caatctccag cagacacagc tcgccgagct cttgggtttc   1560
 taagcagcag gaagctcaac ctaacgctgg ccacacgctg acagctgagc ccatctgaga   1620
 acacggcatc ttcacacagc gagacgcctc cactgagggg aggcccggga gtatcaatct   1680
 gtcaccagtg gccacggaga cctctcagca cccttagttc aaggtagtct ctgtggatca   1740
 ggttggtaac acctactggt taatcaagtc ccactgggga aaggtttgga cggtagaatc   1800
 aagagctgca gtttccttgg cccacaagat gctcttatgc tgtaaaaaaa atgctttaag   1860
 aattgtttgc aaatgaattt acagggtggc cactggacac ttcagagttc ctatttactc   1920
 cccccgccac agctaggaag accagcaaga actaaaggtt tgccgtttta ctatttaaaa   1980
 tgtggacctc tttgtccagg agcgggaggg agaatggcat ctcaccccat tacaacagct   2040
 ggggaactgg ctaaagagag ctgtcagaga gtatccttgg ctgtcctagg aatgactcat   2100
 ggaaagcgcc ccagtgcagc agtgttttca ggaaaaccca gtgggcacgc gccatcgccc   2160
 tctcctctcc tctcacgctc cttttgaaaa gaccgcactc ggcgcccaag gggacgtgct   2220
 caagagctgc aggggcaggg cccaggcaaa aggtgggtga tgactacctg ctgctttccc   2280
 tactccgtag atgggtctgg aacatcgggt aaaacccagt cctcctctca gtgcatctct   2340
 actcaccaac aatggtgaat ctcagctctg tgtattcaag acaggcaaaa cagaatatgc   2400
 ctcattatgg ctggagcgtg cctctacttt gagataaagc tggatgacag gtggatcctg   2460
 gcccacttag gagacatctt tagaaaggga aaggctgtct ttttgtacag gtagtagaac   2520
 aacaaggtca gctgagctta aggctgtggg gttcgaagca gcccttcaag aagtcatcac   2580
 ccctgaagta gtgcctgcga gtcagtcaga ggcataccaa accctgagac agaatcaggc   2640
 acaagttcac aacttttttt ttttttgggg gggagacagt cctactctgt cgcccaggct   2700
 ggagtgcagt agcgcgatct cagctcactg caacctccgc ctcccgggtt caagcaattc   2760
 tcctacctca gcctcccgag tagcggggac tacaggtgca tgccgccacg cccggttaat   2820
 tttttgtatt ttagtagaga tggggtttca ccgtgttgcc caggctggtc gcgaactcct   2880
 gagctcagcc aatccgccca cctcggcctc ccaaagtgct gggattacag gtatgagcca   2940
 ccatgcccag ccaagttcac aacttctgat atcaagttgt tgctgagaaa aggtcaggac   3000
 acttcttaag tagagaagga ctgtgacatc ccctccaaac ctccatgtaa cactaacaaa   3060
 tggcctcatt tacacgatta aaaacaaaat ggtatcgtca ataaatgcaa accttaaact   3120
 gc                                                                  3122



      <210> 2104
      <211> 567
      <212> DNA
      <213> Homo sapiens


      <400> 2104
 atgacagatt cctgtgcgaa gctaattttc aaaaggcagg aagaagacag ccctaagaaa     60
 aaatctgagt gggaacagcc agaaaagaaa gaagaaaagg agtttaaatc aggaatgcag    120
 caactagtgt caaatgatac agagaagtca tggtctctga gtcttgagaa acccccgctg    180
 gagcccgagg aagaccgtat tatttttcag caccggggac agcgccgcgc tgccattaac    240
 gtccaccctc ccccaccttc tctctccgcc accccccacc cgccccaacc tcagccccca    300
 cccccgcacc agcacaatgc caaggcccgt gtcgctacca ttcggacaaa acgcacatca    360
 aattgcagaa ttcggtcccg gaaggttagg aaatcgcccc cggagaaatg ggtgggattt    420
 aataggcggc caaaggcttc ctgtccgtcc cctcctggag ctgcccgcgt tgatgtgggc    480
 ggggagaccg aaaggagaga gcaggctgcg gctcctggtg aaatgggaaa atgggctcga    540
 ccgggggagg agtatttcca ttcataa                                        567



      <210> 2105
      <211> 2106
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(2106)
      <223> n = a,t,c or g


      <400> 2105
 agcggccgcg gcccctgccg gcggcaatcc tgagcagcga ctggactacg agcgggctgc     60
 ggcgctgggc gggcccgatg gacgagcctg gggcggccga agcccacttc ctcccccggc    120
 accgtaagct caaggagccc ngggcccccg ctggcctcct cccagggcgg ggagccccgc    180
 gccttccccg gccggctgcg gcggcggcaa gggcgggggg cttgttactc ccggccgggg    240
 cggcccccgg gcagcaggaa gagagctggg gcggttcggt gcccttgccc tgtccgcccc    300
 cggccaccaa gcaagccggc attggggggg agcctgccgc agccggagcc ggctgcagcc    360
 cccggcccaa gtatcaggcg gtgctgccca ttcagacggg ctctctcgtg gcggcggcca    420
 aagagcctac gccctgtgct ggggacaagg gtggggcgga ctcccccgct gccaccgcct    480
 cggacccggc gggaccccca ccactacctc tgcccgggcc gccacccctc gcgcccaccg    540
 ccaccgacgg gaccctggcg gccagcgagg gcagatggaa gagtatgagg aagagccctc    600
 tcgggggtcg gtggcggctc gggagcctcc agtcaggccg cctgcctcaa acagatcctt    660
 ctgctgcaat tggacctcat cgaacagcag cagcagcagc tgcaggccaa ggaaaaggag    720
 atcgaggagc tgaagtcaga gagagacacg ctccttgctc tggattgaac gtatggaaag    780
 gcggatgcag gctggtaaag aaggataacg agaaagaaag gcacaagctg tttcagggct    840
 atgaaactga agggagagag ggaaccggag ctatctggga aaaataaact ggagtgccag    900
 cccggagctt tcccgagaca tcccaagact ctgcctccca agcccttctt catgtgggcg    960
 gagtggaaaa gggacataaa aggaaatccc catttgggaa gtacagaaaa gaaaagactc   1020
 cctgttaaaa agctggcttc ctgaattttc aaaagtcaaa acaaaaactc ctaagcactc   1080
 tcctatttaa agagggaacc ctgtggttcc tttatcttga aactgtttgt aaacgtggat   1140
 tgagggagcc aagaaacccc agaaaagccc cggtctttca gtgggacacc ccaccaagac   1200
 tctccactcc ccaaaaggga cccagcaccc atcccaagga gaaagccttc tcaagtgaga   1260
 tagaagattt gccgtacctt tccaccacag aaatgtattt gtgtcgttgg caccagcctt   1320
 cccccatcac cgttaccatt acgggaatcc tctccaaaga aggaggagac tgtagcaagt   1380
 aaggccatag agaacacttg ccccttaata cccctagtgg tggcggtcaa gcctaacaag   1440
 tgtgaaaaaa tcctttggat ttttttaaaa aagtgcaatc aataaagcca gagttctgtc   1500
 aagaatgagt aagttaacag ccagagacag acactgtgca ggcattgcaa atagatggaa   1560
 ttacagcaaa atgtgctcaa tgtatttgcc ctgcttacaa cactggggag atgtgtttgc   1620
 caagtaagtt gctcatcaca agagcaccca gacttggggg gtgtattctc cggccaactt   1680
 gccatgcccc tctgaaagaa gggttttctg tgcctgtgaa atgcatagaa ctatactttg   1740
 ccatgcacga ctgttccctg caatttgata atttgtgtga aatctgggaa ggtgggtctt   1800
 tgggtgttct caggggccaa tggtaatttt tgggttgggg agccagcttg gggtggggga   1860
 acttttacct ggggccttcg cttctttaac tatataaagc cctttatctg tatatttatg   1920
 tccccgtttg gggggcagga ggaatttgcc aaaggcccac cgttttactt tatccttact   1980
 atacttcaca aaggttctaa aaatgtgaag agtttacttg gaattgcagt agccccattg   2040
 gatggttcat atatttaaat cacaatggtc tacaaactat ttttcaaaca aaaaaaaaaa   2100
 aaaaaa                                                              2106



      <210> 2106
      <211> 442
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(442)
      <223> n = a,t,c or g


      <400> 2106
 cccacgcgtc cgtgttcagt gggcccagct gtctcaggat aaaaaggggg agatgaactc     60
 aatgacctct actgcgggac ctccaggcag ctcttcagct ccctgtgcaa caagaaggaa    120
 cctgctgcaa aggcagcacc tgcagcgcct ctcaggggaa tttaaaaaag atcctgccac    180
 gtactcaaag cacctggagc ctctggagga agagagggac aaatgaggtc aagtcagagg    240
 aggaagctga gggccccgag tcccttctgc tcagatgtcc gcatccagag aggagttctg    300
 cttctctcaa cctgtgtttc ttgcaagagt ttatctataa attgctgaaa aatgggtaaa    360
 aaaannnaaa aaannnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna    420
 nnnnnnnaaa accccggcgg gg                                             442



      <210> 2107
      <211> 315
      <212> DNA
      <213> Homo sapiens


      <400> 2107
 ggaattcgga actatgttga caaatttcaa aaaagaatct gagggagact atggagtgct     60
 atgacaccag gaaaacttaa aactttgtgt aagatagact ggccagcatt agaggtaggt    120
 tggccattag aaggaagcct ggacaggtcc cttgtttcaa aggtatggca caaggtaacc    180
 tataagccaa ggaacccaga ccagttccct tacagagaca cttgattaga gctggtttta    240
 gaccccccac ccccaacaca tagtggttga gagaacagca gcataagtgg ctggcagagg    300
 caaggaaaga ccagc                                                     315



      <210> 2108
      <211> 967
      <212> DNA
      <213> Homo sapiens


      <400> 2108
 cttaaaaaga ggccgatttc atctcaaacc ctggtgcaga ggtcctaggc agagtgggaa     60
 acttgccctg gagaagcaga agcagagacc aaatggctat ctagtaagga tgttttataa    120
 tgaatccttc attcctttaa agagcccatt attttctgag gcttcatggg atgcgtaata    180
 gcccatgcct tcactgctaa gcataaaaca tggagctctt agtagcctct aagacaatca    240
 tccgtcattc ccacgattgc cttcatcaag gccaggtact aaagaagtgc tcaaagaaat    300
 acacatttct gatacaacag ctgatgtaat tttttatccc atttatagaa tgagtgagat    360
 gatatttcga agaataaaga tgccctggct ttggcttgat ctctggtacc ttatgtttaa    420
 agaaggatgg gaacacaaaa agagccttaa gatcctacat acttttacca acagtgtcat    480
 cgcggaacgg gccaatgaaa tgaacgccaa tgaagactgt agaggtgatg gcaggggctc    540
 tgccccctcc aaaaataaac gcagggcctt tcttgacttg cttttaagtg tgactgatga    600
 cgaagggaac aggctaagtc atgaagatat tcgagaagaa gttgacacct tcatgtttga    660
 ggtattgtat attgttaggt tcagatatca ttaaacaaat ttcagttatt gttagaatct    720
 ttatcattat tttttaaaac aatcatattt tagagtaggt taactaaaga agactcatta    780
 tattttaatt agaaattaca aaatttaaga aactgattaa gtaccagctc aacttcttca    840
 gaaaacgatt ttgactagtg ctgggcacag cagtagacac atttgttttt cctcaagaaa    900
 acctaagatt tgtcagagtt ttcccaagca gaagagcagc cagagattgc tctcagttct    960
 ccatgtg                                                              967



      <210> 2109
      <211> 1991
      <212> DNA
      <213> Homo sapiens


      <400> 2109
 tttttttttt ttctgatcca tgcatccttt attccattac caaccactgt gccgcatcca     60
 agcaacagta cacaaactgg caatcaaccg cagtccagtt gtacaacgat ctgaggctta    120
 cagtacattt aaggctttta aatgtggaaa aaaaaattaa aaccaaagaa cccccaaatc    180
 caaaccccta accaacacaa gtagtatagc aatgttaagc atctcctatt tctgatgctt    240
 atttggcgca acttccagtg tcaaaaccca aataattcct aaactaaaaa gattagttta    300
 gtgaaatttt aattacataa attcttcaaa gcataaactt ggaatttttg tcttggaaat    360
 gttataaaat ttttaatagc aaaacatagg aataaaaaca tattaacaaa atgtattcaa    420
 tcatttacat tacaaacaag gaatctgcag ttcattgttg tagcctgaca aaagaaatca    480
 tatctaccat taagaatcta tgcacaatgt gattgcaaat atgtacagta ctttaaaaaa    540
 gcctacaagg aggactttac agaaggaaag tcagctaggc tctttgttaa accaaccaga    600
 caatcaaaat agtaaaactc tgttggctag taataaattt acacttaaaa aaacccctag    660
 tttctttttg tttaagaata ttccagttat atttatatgg ttacagttga tgaagctgta    720
 cacgagagtt ccagtaaatt acccttcagt tcatttgtcc gggaaagatc agcatgttaa    780
 caaaaaataa taaaggaatt ttcaccacac tagctttcca gttacactat cacagcttca    840
 caaatggatt gaacccatgt atccagtggc agaaagagag ctgcatgtga aataccgaga    900
 acattggtgg caacagggca agtcctgcat gaatgtcaga aatgatggat aaggttgaga    960
 aacagatgcg aggctacttt atacagcact agaaaattgt ccctacattc agctctcatt   1020
 cccattcctg caaggtaatg aagctgggaa tcacgactgt tcagtttaac gtgttgtgtg   1080
 aattagcaga accacctcta gatacaaaag actgagattt catcagctct ttgattagaa   1140
 caccctaaag gttgggcact tcttcatggt tatcaagcct ttacagctac ccagttaaag   1200
 catgtgcaaa acagaggact cttctgttca cagtaaatga ggtaagatca agttgttgtc   1260
 ttcaggaatt aggaagttcg tgagatatga actgttttag tctttctagg tattgtgcat   1320
 aaagctctat gtcattatgc ccagcccctt caacccaaag gggctccacg gctcggggac   1380
 agcgctcgta catcgctagg ccatgggaga aatcgatgac ctcatcctct gtaccatgaa   1440
 tgaccaacac aggagaggtg actttagata tcttgtcaat gctggggaaa gcatcaaagc   1500
 agtatgtttt cctggtatcc ggaaaagcca cacgcaaacc agacatcaga ggggaatgga   1560
 gaattaccgc tgcgcattca tacctcgagg ccaagtctac cgtggggaca gtcccaatgc   1620
 tctgaccata gaggataatg ttctcgggac tcacgccata ccgggtgcgc agcgcctgcc   1680
 acgcggcgtc gatgtcggcg tagaggttct tctcggaggg cttgcccgag ctgacgccgt   1740
 atcccgagta gtcgtaggag aagatgttgc agttgatgcg ggagccgagg ccaatgtaga   1800
 agctgcacat ctggcccagg tccacggcgt tgccgtgcga gaagagcagc gtgtagcggc   1860
 tggagggcgc gcagcgcacg aacatgcagc cgagccggtt gtcccgggcc gtgcgcgaga   1920
 agaagacctc gacggcgttc cagcccgctg cgagtattgc cagtcggcgc gctcgctgag   1980
 gtgcaggctg c                                                        1991



      <210> 2110
      <211> 990
      <212> DNA
      <213> Homo sapiens


      <400> 2110
 tttttttttc acattcctac aatcaagttt attactcaaa gcaaaagttg tccatataat     60
 acattggtcg tcaattttta tttccacatg gttacacagg ctgaatgact agctcacaat    120
 cccaggaggt attataagtt ttgctcttca aaaaatggtg ttactgttgt aaggggaaaa    180
 gtcctcaatg acaaagaaat gacactaatg aaaacaaaat caagaatgat ccactggtac    240
 tgcaggttac agagaagctg tcagtgagca gttccccacc tctcgcaagc aaaggggatc    300
 aagggctaaa aataccttag aaaaatcaaa cagcacctgc aacacatgct tatataaagg    360
 ccaaacttgc aaattcttcc ttctcgtcca tgctgcccaa atgtgaagga attacatata    420
 aggctaaaat ctggcgaatc ttctcacttc ttcctcttct ttgtggaata taatttttct    480
 gcgagtggga ctgggacaat cccttcacat tcttttagtt cctgggtcag agggtgtttg    540
 acaatattcc ctctaatcac atctatatct cgagacaagt gctccaccat gctttcaaca    600
 gctgcggtgg gtgcataaaa atccaccaag aaatacccgc ctctgttgtg ctgctgactg    660
 tgggcagaga tcctataagg aagcgctcgt tcacccaggt tttccaagtc cctcactatt    720
 gctcctctgt ccatcagggc ctctatcgta cgtttcaaag tagcagcagt ctctggccgc    780
 tgcatggctt tcaggattaa agccagctcg tagcggggca tgcctggagg atcggcgagt    840
 gcggctcgga agccagccgg ttcccgggac gcgaaggggc gggacggcgg ggacagtggg    900
 gacctagaaa ctgctgcgcc ggacggctcc caggcggcga aagcacggtc cgagagcgcg    960
 agcccgggct taaaggcgct ggcagctgcg                                     990



      <210> 2111
      <211> 578
      <212> DNA
      <213> Homo sapiens


      <400> 2111
 atggacaagt ccctcttgct ggaactcccc atcctgctct gctgctttag ggcattatct     60
 ggatcacttt caatgagaaa tgatgcagtg atagaaattg ttcagtgtag gatgtgccac    120
 ctccagttcc caggagaaaa gtgctccaga ggaagaggaa tatgcacagc aacaacagaa    180
 gaggcctgca tggttggaag gatgttcaaa agggatggta atccctggtt aaccttcatg    240
 ggctgcctaa agaactgtgc tgatgtgaaa ggcataaggt ggagtgtcta tttggtgaac    300
 ttcaggtgct gcaggagcca tgacctgtgc aatgaagacc tttagaagtt aatggttctt    360
 ctgtgactcc aatttctggg tgaggttgtt gcctcagcct cttcacaatg actttctaaa    420
 aaaaatcaca cacacacaca cacacactac agaagaggat tgcaaacaca tggctccatc    480
 ttctgcacac gaaaggaaag tccctctcct tttctacagt ctctgtcacg ccccttaaaa    540
 taagtaaata aataaccttg agagaaaaaa caagaaaa                            578



      <210> 2112
      <211> 392
      <212> DNA
      <213> Homo sapiens


      <400> 2112
 cactgtgcgg cctgaccatc ccggtgcctg tggcatcctc cggacccttt ctaggcctgc     60
 gcctggtcac gagaggccgc cagccccgcg tggacttcgt gggcgaagtc acctctttcc    120
 gtctgggacc ttgtggtgcc tacttccgct gccagaatgg caggtgcatc ccctcaagcc    180
 tcgtgtgtga cccctggggc atggacaact gtggcgatgg cagtgaccag ggctcctggt    240
 caccagctga ctgcagaggt tggagtgcag tggcaccatc tggctcattg caacctctgc    300
 ctcctgggct caagcaatcc tctcgcctca gcctcctgaa tagctgggac tacagggacc    360
 ctcaccgggg acgtggacag cacttgagcc aa                                  392



      <210> 2113
      <211> 5402
      <212> DNA
      <213> Homo sapiens


      <400> 2113
 gccggttccc aggccgggtg gagaccaact ctggggtctc ttggtgggag agtggggagc     60
 ccgtcttctg ctgagtgctg ccgccccttc ccaggacagc ggaggtggaa cttcgtcgcg    120
 ctgcaacccc cggctcggga tcctggggcg tcctttggca gttgattgca ccctgcacta    180
 gagagaagtc caggaatgat atattcttgg gctgtatttc tctaccctgg agttcatcca    240
 gttcatccca gaaacactga cctgattact gtgacaaagt ctgatggata gaccctttct    300
 gttgaccttg tggcgttttt ctttcatgtg gaagttggaa gacaaggtga aaggggccaa    360
 aagttacctg ctttggtgaa taggagtgct ctacttggtt ctcagaacat gggccctcgt    420
 ttaaagctgc agctgtgatc ctcggctgtc tgttggcatt gacgggacct gatgttttac    480
 gttattggtg gaatcacagt gtctgtggtt gcattcttct tcacaattaa gttcctcttt    540
 gagcttgccg cacgtgtagt cagcttcctc cagaatgagg accgcgagcg ccgaggggac    600
 cggactattt atgactacgt gcggggaaat tacctggatc cccggtcttg caaagtctcc    660
 tgggattgga aggaccccta tgaggtgggc cacagcatgg ccttccgagt gcatttattc    720
 tataagaacg ggcagccttt ccctgcacat cggcctgtgg gactaagagt tcacatctct    780
 catgtcgagc tagcagtgga aattccagtg acccaggaag tccttcagga gcccaattcc    840
 aacgtagtaa aagtggcctt cactgtgcgc aaggctgggc gttatgaaat cacagtgaag    900
 cttggtggat taaatgtggc atatagtccc tactacaaaa tttttcaacc tggaatggtg    960
 gttccttcta agaccaaaat tgtgtgccac ttttctactc ttgtattgac ctgtgggcag   1020
 ccgcacaccc ttcaaatagt accccgagat gagtatgata atcccaccaa caattccatg   1080
 tccttgagag atgagcacaa ttacaccttg tccattcatg agctcggccc tcaagaagaa   1140
 gagagtactg gtgtctcatt tgagaaatca gtaacatcca acaggcagac tttccaggtg   1200
 ttcttgcgac tcaccctgca ttctcgaggc tgcttccatg cttgcatttc ataccaaaat   1260
 cagccaatca ataatggtga atttgacatt attgtcctaa gtgaggatga gaagaatatc   1320
 gtcgaacgca atgtgtccac ttcaggcgtg agcatttact ttgaggctta tctttataat   1380
 gctaccaact gtagcagcac tccatggcac ctgccaccca tgcacatgac ctcttcccag   1440
 cgccggccat ccactgctgt tgacgaggaa gatgaagact cgccctctga gtgccacacc   1500
 cctgagaagg tgaagaaacc gaagaaggtg tactgctatg tgtcaccaaa gcaattctca   1560
 gtgaaggagt tctacctgaa gatcatcccc tggcgccttt acaccttccg agtgtgtcca   1620
 ggaacaaaat tttcatacct tggtcctgac cctgtccata agctgctcac actggtggtg   1680
 gatgatggca ttcaacctcc tgtggagctc agctgtaagg agaggaacat tctagcagcc   1740
 acttttatcc gctccctgca taagaacata ggaggctctg agacctttca ggacaaggtg   1800
 aactttttcc agcgagagct tcggcaggta catatgaaaa gaccacattc caaagtcacc   1860
 ctgaaggtca gcagacatgc cttgttggaa tcgtctctga aagccactcg gaatttctcc   1920
 atctcagatt ggagcaagaa ctttgaggtt gttttccagg atgaagaagc tctggactgg   1980
 ggagggcctc gccgggaatg gtttgagcta atctgcaaag cactatttga taccaccaat   2040
 cagctcttca cccggttcag tgacaacaac caagcattag tgcatcccaa ccctaatcgc   2100
 cccgctcatc tgcgcctgaa aatgtatgag tttgcgggac ggctcgtggg caagtgtctc   2160
 tatgagtcct ctctaggagg agcctacaag cagttggtcc gagctcgctt cacccgctct   2220
 ttcctggccc aaatcatagg actgcgtatg cattacaagt actttgaaac agatgaccca   2280
 gaattctaca aatctaaagt ttgttttatc ctcaacaatg acatgagtga gatggagctg   2340
 gtctttgcag aagagaaata taataaatca ggtcaattgg ataaggttgt agaactcatg   2400
 acaggtggag ctcaaactcc agtcaccaat gcgaataaaa tcttctattt aaatttgctg   2460
 gcccaatatc ggctggccag tcaagtgaaa gaggaggtgg aacatttcct aaaaggcctg   2520
 aatgaattgg tccctgagaa ccttttggct atttttgatg agaatgagct tgagctgctg   2580
 atgtgtggga ctggagacat cagtgtgtct gacttcaaag cccatgcagt agttgttggt   2640
 ggctcatggc atttcagaga aaaggtcatg aggtggtttt ggactgtggt ttccagtctg   2700
 acccaggagg agttggctcg gctacttcag ttcacaacag gctcctctca gctaccacct   2760
 ggaggctttg ccgccctctg tccctcattt cagattattg ccgctccgac ccatagcacg   2820
 ctgcctactg cacacacatg ttttaaccag ctgtgcctcc ctacatatga ctcctatgaa   2880
 gaggtgcaca ggatgctgca gctggccatc agcgagggtt gcgagggctt tggcatgctc   2940
 tgaccactct cctgtcatcc agttggctcc catgctctct ggagcttctg ggcgcaagtt   3000
 acagacatca taaccactga tcctaacaca cataaccatc agccagaaga tgccgcatgc   3060
 tcccctgtgt ctggaggatt ttgtcaccta caagccttgt ctttacctca cctgctccct   3120
 gcccatatct accacaggcc actttggcat ggtatgtaag ctgagctctt cattctgtca   3180
 tgagaagagg accatgctgc tatcatttat ttggtccttt gaagatctca gtagctgagg   3240
 gagatggcac acggggctca gccctgttgg gaaactggtg tggagaccct taaatccaca   3300
 ctgtgctcca aaactccctc tgctgatact ccttggagac accctctttg gccctcacta   3360
 cttgaccaga ctggtacttg agtccttctc atgggtgggg tgattgcctc ttctcatcag   3420
 gagccaggag agagggggac agataggagg tggcccatag gagcagtccc gctgcacaat   3480
 ggtaggcata ggccatggca ctggactgcc tctaaggact gctaaaaaga atattttttt   3540
 gtggtgtcag aactggaaaa agcactttcc cttcgggcat ttctggaaat gattattaat   3600
 cacaaagaag aactctgtaa gctttttctt gaattgtagc cagtgagaaa agcagataga   3660
 ctgaagaata tgaaggatag ctgagctgta gcctccagag tggggcatgc ctaggcatat   3720
 ggctggcttg gagactactg atgcttttcc ctgagtttgt tattggcact gaagtatggc   3780
 cggcttgggc cactgacttc cccattatgt agtctgctaa aagctgggga tcctttagca   3840
 ttctactgaa gaaaattttg tagcaaaaga ttagaacagt aagaatagta tgccagcaat   3900
 ccctgattct ctctctgctt ggtgttctct ggcagcacta agacaaagga acagggacta   3960
 ggagtttacg tgcttatcac aggtccttgg cgtcaggaca ctagggatga acatggaggt   4020
 gatatgttac acagtaaaca cctgccaacc cctgtactcc cctttgctcc atcagttatc   4080
 aggaaggaga actaaggagg gaggaagctt attaggttca ctgttgaatg atgattgaag   4140
 agtacctgct gctgtatctt ggaagatgac aacatccttt ttcattactg tttgattgaa   4200
 aataatttca agattcaaaa tctcattgac ttcccaaatt tgtgttttta agaaggcttt   4260
 gctgcaagct accattccca atggggcagt caactctgag aatattacaa gccatcttta   4320
 ttgccaaaac cagcaagtac acagagtcct gaaacaaggc aggactttgg caatgccttg   4380
 gcctcctgga agcatgtctg agccctcctg ttcgcaggga tcatgaggaa caagccctcc   4440
 tgagctgcta cagttcctgc ctgacctcag tctttcgcag tcatcatttg tcctttcttg   4500
 gcacatgggt gctgacctca ctcatccttg gggtccggga tccagcatca gggtctctat   4560
 accccaggat cctccatgcc acatggtcac tgctctcctc agggaccagg acaaggtgct   4620
 gctgcttgcc caaatgtttt cccatgggat atgtaccgga aggtttatca ccaccctggg   4680
 aaacataatg ctgccccttg ggcccagaaa ggggtttcca gctgggggca cgtggactgg   4740
 ttctgctgtt tttggcagtc gcttttctga attctcccct ccggcagcct tccagagact   4800
 gatcctggag attgagttga ttgtcttggc tagacctgtc attttaagct ctagtcatag   4860
 cactttttca gagcatctta ggcaccattg caacccaacc agggaagctg catccctgtg   4920
 gtggtcctta ggcaccagtc tttgttaaac aaaacccttt ggcactattg tggttttcta   4980
 ttctctgtct gaactctatt caaaagtatc tttgctctct tgggcctttt cttttactgt   5040
 tttgtttttt ttttctaatc ctgctttcat actagccagt gtggggaaaa ggtacaatat   5100
 gtcaaagaga tgagagagtg ttatttcttg ggcaattttc tattagtgtt tcttattttg   5160
 gccagttctt ttatttatgt ccttgtgacc caggtacttg gggggccagc tacccttctg   5220
 gccttttagc gtctttgaag gagaccagac atgagtgaat acctaggaga gtgtcagcat   5280
 gtttctggaa aattggcaga gaccaagccc tgctgcagat tcgtcaggcc aggtgaaagg   5340
 gccaggcagt tgcagctgat gatgtaaata ttttgtacag tagataaata aatgtttaaa   5400
 ag                                                                  5402



      <210> 2114
      <211> 865
      <212> DNA
      <213> Homo sapiens


      <400> 2114
 tttttttttt ttgagccaga gggaccattt ttattagatt ccagcaagac tactgtacat     60
 gtttcatgca gattaaatat gtgtcttcac tgcccctggg aggggagcac tctcactgtc    120
 agctccttca ttggtgtgtc aaggggtgag tgtcaagggg agctctcaat gtattccgta    180
 tggggggcag ttgggatcat gactcggggt agaggtgaga cagtaggtag ctgagggtcc    240
 ctgggacctt gagtcttcag aggttcaggg actgcaggac cttggtcctt tgctggtact    300
 ggcaccagag gatcttgatc cttcagaggc actgggacta taggaacttg attcttcaga    360
 ggttcaggga ctatacgacc ttgattcttt ggaggctgta ggactgtggg gccttgatcc    420
 ttaactagta ctgggagaat ggggtcttga ttcttcacgg actcggggac cacaggacct    480
 tgattcttta caggtgccac aactgcagaa tcgtgaacct ttgcatgctc tgggactaca    540
 acatcttgat ccttgactgg ccctgagacc actaaacctt gattctttac aggctcagag    600
 accatggaac cttgattctt tatgggtgct gtggccatgg cactttcatc cttcggatgc    660
 tctgggacca tgggatcttg atccttgata ggtgctgaga ccatgggacc ttcatccttg    720
 acaggtgctg ggactatggg accttcaccc ttgacaggtg ctgggactat gggaccttga    780
 tccttgacag gtgctgagac catgggacct tgatccttga cagatgctga gaccatggga    840
 ccttcgtcct tgacaggtgc tggga                                          865



      <210> 2115
      <211> 909
      <212> DNA
      <213> Homo sapiens


      <400> 2115
 gcggccgccg gcgccggtag ccgcgtcccc ctgcgccgcc ccgggcctgc cggccggagg     60
 agccaccata caccccgggt cgccgagcgc ctggccgccc cgcgcccgcg ccgcgctccg    120
 cctgtggctg ggctgcgtct gcttcgcgct ggtgcaggcg gacagttttt ttttcccagt    180
 gaacgtcacc gtcaggcacc tcaaggccaa ctctgcagtg gtgagctggg atgttctgga    240
 ggatgaggtt gtcatcggat ttgccatctc ccagcagaag aaggatgtgc ggatgctgcg    300
 cttcatccag gaggtgaaca ccaccacccg ctcatgtgcc ctctgggacc tggaggagga    360
 tacggagtac atagtccacg tgcaggccat ctccattcag ggccagagcc cagccagcga    420
 gcctgtgctc ttcaagaccc cgcgtgaggc tgagaagatg gcctccaaga acaaagatga    480
 ggtaaccatg aaagagatgg ggaggaacca acagctgcgg acaggcgagg tgctgatcat    540
 cgtcgtggtc ctgttcatgt gggcaggtgt cattgccctc ttctgccgcc agtatgacat    600
 catcaaggac aatgaaccca ataacaacaa ggaaaaaacc aagagtgcat cagaaaccag    660
 cacaccagag caccagggcg gggggcttct ccgcagcaag gtgagggcaa gacctgggcc    720
 tgggtgggcc accctgtgcc tcatgctctg gtaatccctg gactgcagag ggggtcagct    780
 cggggactgg catggcgaca gctgggcaga gccagacttg gctgctgcct gtgtgacaca    840
 gggacactgc aagttgattt tggatcctct ccttttgcag ggtgccaggg gccagtggtg    900
 atttgaaaa                                                            909



      <210> 2116
      <211> 1849
      <212> DNA
      <213> Homo sapiens


      <400> 2116
 tgaagaactg ctgtgtttag atgtctctga aaacaggttg gaaagacttc ctgaagaaat     60
 cagtggcctg acttcattaa cggatttagt catttcccag aacttattag aaacgattcc    120
 ggatggcatt ggaaaactaa agaaactgtc aatcttgaag gtggatcaga atagactcac    180
 acagttgcct gaagcagttg gggaatgtga aagtctcact gagttagttc ttacagaaaa    240
 tcagctcctg accctgcctt aaagcattgg aaaactaaag aagttgagca acttgaatgc    300
 agacagaaat aaattagtgt ccttaccaaa agagatcggc gggtgctgca gcctcactgt    360
 gttctgtgta cgtgacaaca gactaactcg gatacctgca gaggtgtcac aggcaacaga    420
 acttcatgtc ctggatgtgg cagggaacag gttgctgcat ctacctttat ccctgactgc    480
 cttgaagttg aaggctctgt ggctatctga caaccagtcc cagcccctgc ttacattcca    540
 gacagacaca gactacacca caggagagaa gattttaacc tgtgtcttac ttcctcagct    600
 gccttctgaa cctacttgtc aagagaatct gcctcgctgt ggtgcactgg agaacttggt    660
 aaatgatgtc tctgatgaag cctggaacga gcgtgctgtc aacagagtca gtgcgatccg    720
 atttgtggag gatgagaaag atgaagaaga caatgagacg agaacacttc taaggcgagc    780
 cactccacac ccaggggagt taaagcacat gaaaaagaca gtggagaatt tacggaatga    840
 catgaatgct gctaaaggac tggactcaaa caaaaacgag gtcaatcatg ccattgaccg    900
 agtgaccact tctgtgtagg agtttcacct ccaagtttta cctcctgtgt cttcctctgc    960
 tgtcgagacg ttcctgtctg cttcccggga gcctcacgtg ctccttgtcc taaccagccc   1020
 ccgcgcgcca tcttcccgtg gagtgtgggg aagctgctgt ctcccaggaa gtgccttact   1080
 catcccgcaa ccagtcagcg caccagtggt ctcccggtgt gatttttttt ttttttaatt   1140
 tcagttgttt gtaataagta gaatacacta ctgtaaacat acgacctttg tttttgtctt   1200
 atgttggggt aaaggaaagc aggaagggga atttttatcc tcctcccttc cgtaaagtgc   1260
 tgggatattt tgaatccccc aagttccctt ggacctactg atgagagata gttttatgta   1320
 tggggaaaaa tggatacttt ttaaaccttt tttggcagct cagatggtgt aaattttaaa   1380
 attttgtata ggtatttcat aacaaaaata tgtatttctt ttttgttatt ttatcttgaa   1440
 aacggtacat attttagtat ttgtgcagaa aaacaagtcc taaagtattt gtttttattt   1500
 gtaccatcca cttgtgcctt actgtatcct gtgtcatgtc caatcagttg taaacaatgg   1560
 catctttgaa cagtgtgatg agaataggaa tgtggtgttt taaagcagtg ttgcatttta   1620
 atcagtaatc tacctggtgg atttgttttt aaccaaaaag atgaattatc aatgatttgt   1680
 aattatatcg gttgattttt tttgaaaaga tgaaccaaag gatttgactg ctaatatttt   1740
 attccttaca ctttttttct gaataagtct ctcataatga gtgcagtgtc agactgtgcc   1800
 tactctgatg gtatgtgcca tttgtaaaat aaaatagagc agaaaaacc               1849



      <210> 2117
      <211> 1437
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1437)
      <223> n = a,t,c or g


      <400> 2117
 agaggccnnn naggggggnn aattgaaaac cntaatcgta gaccctagtc agngnggngg     60
 aattctggtg caggaagtgg agggggtact cagagtttga aaattgcaga acgatatgga    120
 ttccaataca tttctgtggg agaattatta agaaagaaga tccacagtac cagcagcaag    180
 aggaaatgga gtcttattgc caagataatt acaactggag aattggcccc acaggaaaca    240
 acaattacag agataaaaca aaaattgatg caaatacctg atgaagaggg cattgttatt    300
 gatggatttc caagagatgt tgcccaggct ctatcttttg aggaccaaat ctgtaccccc    360
 gatttggtgg tattcctggc ttgtgctaat ccggagactc aaagaaagat tactgaagcg    420
 tgcagaacag cagggccgac cagacggaca atgtaaaagc tacccaaagg agactaatga    480
 acttccaagc agaatgctgc tccattggtt aaatacttcc aggaaaaggg gctcatcatg    540
 acatttgatg ccgaccgcga tgaggatgag gtgttctatg acatcagcat ggcagttgac    600
 aacaagttat ttccaaacaa agaggctgca gcaggttcaa gtgaccttga tccttcgatg    660
 atattggaca ctggagagat cattgataca ggatctgatt atgaagatca gggtgatgac    720
 cagttaaatg tatttggaga ggacactatg ggaggtttca tggaagattt gagaaagtgt    780
 aaaattattt tcataattgg gggtcctggc tctggcaaag gcacacagtg tgaaaagctg    840
 gtggaaaaat atggatttac acatctctca actggcgagc tcctgcgtga ggaactggca    900
 tcataatctg aaagaagcaa attgatcaaa gacattatgg aacgtggaga cctggtgccc    960
 tcaggcatcg ttttggagct cctgaaggag gccatggtgg gcatgcctcg gggacaccag   1020
 gggcttcctg attgaccggc tatcctcggg aaggtgaagc aaggggaaga gttccggacg   1080
 caggatttgg agaccccaca gttgggtgat ctgtatggaa tggctcggca gacacccatg   1140
 accaaccgcc tttctccaaa ggagccggag cagcctgcct gtggacgaca ccaccaagta   1200
 ccatggccaa gcgcctagaa gcctactacc gaggcgtcca tccccgtgat cgcctactac   1260
 gagacaaaaa cacagctaca caagataaat gcagagggaa caccagagga cgtttttctt   1320
 caactctgca caagctaatt gactctatta ttttctgaag gcaaaaatgc atgtttgggt   1380
 tagaaatgga aaccagaaaa aaccattaaa aagttcattc cttaaaaaaa aaaaaaa      1437



      <210> 2118
      <211> 3344
      <212> DNA
      <213> Homo sapiens


      <400> 2118
 tttttttttt ttcaaagtac ataaaacttt taatgaatta actttacaaa agacaaatgg     60
 catcaaaaca tcagacgagt ttgatacaaa actggtccta ggctgtgagg actaattctg    120
 gtgacggatg gcgacgtgct gctggcatga gacacacgga gcagagggac gagagccgtg    180
 ggtcccaacg ggggcccttg gacaccactg gcaatgagac aatgggtgag cacagagtcc    240
 acgtggggga cagaatcaac ttattcacga atactgtgtg tttgaatatc agatgagcag    300
 atgcggttgg cgaggctacc atattttcca gaaaagaaca tgccccagaa gataatatac    360
 accccctagt tttattgcct taagaatgtg tgtgtgtttc acctttctcc tctgttagtt    420
 ctcccagtgc ttttcttcta tcacgcgcgc tccttttccc ttttgcttag gagcaagcac    480
 agtgcaagtg gcagaacgat ctgggcacac atcagacacc aaacggtatg ccactgggtc    540
 acgagaacga gtctgcagag gctccatagg acagacagca cgcacatcaa aaacaaggga    600
 cagaagttgc agtcagaaag tgtgtgatac cttcctgaaa atacagtctt cttgccaaaa    660
 tgaaggtgac tcttcaggat gccacgttgc tctgggaaag ggaccttgac atttctgtgt    720
 ttacaaagta cgtcttcagg tccccctttc ctttcacgtt gattattcct cgacaggtgc    780
 acgtgtatcc gagggtctgc aggacgaggc tcgtctcctc ggtaacctgt attttgtcca    840
 ggactccggt gctgtccatc ctactggcca cattgacagt gttgccccag atatcatatt    900
 gtggcttctg agctccaatc acaccagcta tcacaggtcc atggttaata cccactcgca    960
 atttgaagtc gttgaaggag tgcttgttga tggcatccag cttccctacc cagggcaaaa   1020
 gcaaactacc accatggtgc caatgtgcat gtactgtcgc tcgggctcct gggagtgctc   1080
 ctggctgggc acagcgctca gacctgttgc tgccatgtat gtgctgccaa tggtcttaat   1140
 cttttcaact ccactgaatt ttggcttgga aagaagatca tcaaaagtca gcgatgatct   1200
 cgttcacgga gccgaaggca ttccaagccc tccttgttca cgtcggattc tgtataaaat   1260
 tctttgaaat ccggaatgga ggcaaacatg acgcagacgc agtcatagga ctggtggtat   1320
 agctcctcat tcttcaggct cctggccagg aagtgctcag cccacgtgcg cgggaagcac   1380
 gttctccagc agcacgcggt tcaggttctc catggtctct atctcctccc gctctttttt   1440
 gaatttgttc ttccataaga agtctaacct acagtaatat tcattctgtc tacccagaac   1500
 aagcagtgtg atgaagaata tagagagaga cacagagccc atggtcttca ggtctttcca   1560
 aatgcctggt ctctcaaata agacctggct gtagtcgccc aggacgtggg cgtgggtgtg   1620
 gagtaggatg gtgttgtagc ccaccaaggc caccatcatg atcaacatct tcagctcata   1680
 gtttacccgc aggaacaccg gaacaggata tcagtcccag aatgcagctg tagataaagt   1740
 acgggaggaa aaataaaatt tgcgcacgca gaatcgccac ctgattattt gaggctgaaa   1800
 agcttgtgtt tgttgtgttg gcagttggag ggattgtttc ctctgagtca ctcaggaaaa   1860
 acatgttgaa cacggccatc attaatatga tggctgtggt gatgatcgtg agagagatcc   1920
 gtggccaggg gcggttggca atgatgcccg aggacttcaa aagccacatg agcaggggag   1980
 aggctttttt gctgcattgc agaagctgtc cagcaaagca gacgaagagg atgaaggcca   2040
 gcaagagaaa cgcagcccca aaggagatgc ccaggacaga cgtttttggc agcacgagaa   2100
 tctgcacaat gaagatgcag aagaatatga gacaggcaca agtcacataa tacttgaacg   2160
 ctggcagtgc cgtggcccgg tactcttttt ctagtacttt gttatagaaa agcagtgaga   2220
 ttctctgaat gtcttcagac ttgagccatt gcttctgtgc attaatccca tcaattgctt   2280
 gaatcatcct ttcattcaat tcttcttcaa atctcttctt ttgtgacttg gttcttaagg   2340
 tgcgattttg aaaattatgc tgacccatgg gtacatccgt ggtgctgatc ttgccgttct   2400
 ctgtggtcat gctgtccctg tgatgtaggt gtgcaaaggg cttggctgcc ccccaggact   2460
 ccaagtaccg ggtcatgcgg accgaggccc tcattttggc tccatcaagg gtgtggcgag   2520
 gtctgaagag atgctggggg ctccgtcgtt ctcccttggg gttgatcaca aagtaggttt   2580
 tcaccaggtg ctgttttaaa tatgggtccc taatgtcacc atctccctcc tccactttat   2640
 aagcgccatt caagtgctcc agggtgacag aagaaatgtg aacacgtcca gggacccctc   2700
 cagcttccat gtggttggcc aaggtcacat catgtgacca cacatcatat tgccacttct   2760
 gcagaccaat cacgccacac aggacattcc cagaatgcac gcccacgcgc atgttgatat   2820
 caactccagt agcatccctc actttcttta tggcttcaca catgtccagc cccattttca   2880
 cacagttctt ggcatggtta gggagagata tagggagtcc agatacacag tagtagcagt   2940
 ctcctaaaat tttaattctc atgcattcat tctcctttgc aatttgatca aactttccaa   3000
 agagctcatt cagcatgtgg actagttctc ccggggagca gtcacttgcc agccgggtaa   3060
 agccaacgat gtcagcgtat aagatgctca cgtttgtatg ccgcttcaca tacaggttgt   3120
 ggaagttatt tgtgttctcc atctggcccg ccttggggcc ctgcagcctc tggatgatct   3180
 ccgctttcat ctccatggcg atgtgggccg gcagcaggga gagcagaagc cgctcctgtt   3240
 gacgtttttc aaattccaac ttgatccgcg acttgatgca atttacaggt gtcctgatat   3300
 gtttgctgaa gagcgagttc catgaggtgc ttatggtagg ctcc                    3344



      <210> 2119
      <211> 5919
      <212> DNA
      <213> Homo sapiens


      <400> 2119
 acctttacaa atagaggtta tttgtaaata aagtgcaggc caatggcaca aagtagtgaa     60
 ggtgggattc actcaggtct gtcacttcca agcccatgtt ttctactttg caaccctatt    120
 tgaaaggaaa actgcaacta agattatgac ccatgagaca acttatgtgt gagacaaaaa    180
 gtttcacacc tccccccacc ccaaacacac acggtataac acagtgaccc aaccttaggc    240
 aaaagggtac cactgccagc aaatgcattt aacattttat tcgagattct caacagctgc    300
 catttggttt gtatagcaaa ttttttacaa agtaaccttt tttccatttt tgatattttt    360
 atgaaaatta ttttcttcag ttttaaagcc ctgtccctcc cccaaagaag gattaataac    420
 taccaagtaa ggattattta ggagaaaaac aaaaggcaaa aacagcttta taaacacttg    480
 tgaaacaggg ggtaagtgtc cgaagtcaag accttctggg cccagtggag gtgctgggct    540
 gctccaggga caacccatca ccacttcacc gatccacaac atcctcaagg aggctgagca    600
 gccctgcaca agaccctggg ggggctttcc tgtttccaca aagctccacg tcccgttttt    660
 ccgtctccat ctttggctgt tgggccttcc cctcccaaat ctggcctaac aaagggcagg    720
 cacgatcttt aaatacctgg tgcagctttg taaatggagc ccaggatact cctattttgc    780
 aaagttgaga ttcccctatc ccagtcctgg gggaggaaaa attcatccca atgtagcatg    840
 gatggtttca ctttcttgtc ccactcagac acatgctcat acttattaaa tggatttatt    900
 ggatgcttca aaagtcctga tgtgtagtag cacaaaagtt ccttgtaaaa aaagaagttg    960
 caaaattata aaaatttctg cagcagttct ggctctggat gacaaagctc attctgatta   1020
 gtagtttttt tgacatgcac agcagcttcc cctataagtc ctacgttcgg agggttccgt   1080
 ttagacaaca ggaagttgga atccaagttt aaaaggctct ctgctgacaa aatgtggtac   1140
 atccatcaac agaattctac tcagcaataa aagggacaaa ctaccaagac gttatctgtc   1200
 atggacaaac cttaaaaaca ttagctaagt aaaaaagcca gacccaaggg accacatatt   1260
 gtatgattcc attgatttga actgtccaga aagggcaaat ttatagagaa agtagattag   1320
 tggttgccgg gggtaagaac aggattaact gtaaaagagc atgaaggatc ttattgggag   1380
 ggataaaaat gttctaaaac tgagtaatag ttacagctac accactgagg gaagttacta   1440
 aaatcactga aatgtacact tgaaatgggt gttttatgat atgtaacata tgcctcatta   1500
 aagttgtttt aagaaaagga ttccctgcct cccaaaccat ccttcaagca ttaaacattt   1560
 ttgggaggcc ccataatcca acagggacag aataactact tagtgatgat ttacagagtg   1620
 aaatatttta ctgttttgta gtaagcacat tttagtaact gtacactagt acaatgtttg   1680
 ttaagatttt atctcatttt tgtcatatta gcctaaaatg tttattttta tttaaaaagt   1740
 agccaatagg aaggtaagat tggggagaaa ggtcagtaaa tgtcacaaaa gagactccta   1800
 gtaacacaat ctgagggagc tttttctttt gaaataaaga tggtgcatct gtccctttac   1860
 agatttctct cctgtcccct gggactgggg aacggtgaat ctcctgcctg acaccttgta   1920
 gagattagtg tatccagcta ttctattgcc acgatgcctc taaaaaccag actgactggg   1980
 aacagcagta gggggttggc cagtgagggc aggtgactaa gtggtgtgca ggaaactcgc   2040
 atgtttccct gggttggctt cctgctcccc tgtccctgtc accaatagca gcttcattgt   2100
 gagaagatta aaacaaagga aaaaaaccca aaaaaactgt ttccaaattg taactaacca   2160
 agtctgtgta ggaaattcac aaggcagcag agcagaggct gcagaggtgc tctgtctacc   2220
 gggagaacta atgatccctg tgagcaatgc agggtgcaat gagtcacatg gggaaatgtg   2280
 gacagaggca gaaggacatc aaggccccca ctacacacca aattagagtc aatcctcctg   2340
 ttctccccac ccacttcgca aactaatgga cgtccgcgtt atcccagagg gagagtggct   2400
 agggacactc agtccttccc aattatgtgg acgtctccaa atcttggtca aatctgtcag   2460
 atttctaaca gtttcaaata cctcaatatc accctaaact gagaaagatt attagcccgt   2520
 gatggtggga cccttattga cgaaggcctg ccccctcctc acagttgggt agattccctg   2580
 ggttcctgat ggttcaggag cctgggctgt catttgtcta cctggggttt gcagcagccc   2640
 tagtacaaga agattcattc gtgctgttta ctttggcagc ctcttcacac aactttcctc   2700
 tctaacacgt gttaattatc agagtattca cctcacctcc ttacttccca gcttctccaa   2760
 aatcaaagca atagtaataa acaatttgga aaatgttgct tagtatttta agccatggtt   2820
 agcattataa ccttaattaa agagacccca ggctggggtg gctcaccaca cccagcctat   2880
 aatcccagca ctttgggagg ctgagatggg agaatcactt gagcacaaca attcaagagt   2940
 agcttgggaa atagagcaag atccagtctc tacaaaaaat aaaaataata aaaataatta   3000
 gctggccgtg gtggtgcgta cctgttgtcc cagctactcg ggaggctaag atgggaggat   3060
 tgcttgagcc taggaatttg atgctgcagt gagctatggt cataccactg cactccagcc   3120
 tgggtgacag agtgagacta tgtctcaaaa aaaaaaaaaa aaaaaaaaaa aaagagggac   3180
 cccagctgct gtgactttgg aaactaaagg tgttaacaaa ggtcaagcct ttccttagga   3240
 tcgtttctgg tttcaccctt atgtgattcc caaaactcaa ctattattgt cagaaactgg   3300
 cccaaagacc cagggtctgc atttgcccag gcctaggtct gtatccttga attttctgct   3360
 gacagttcaa aggcctggag aaactgaaaa tgcattcatt tgggtttttt cccttgaaaa   3420
 gaaagagata aattattttc atcttggaat tttagagttg aataaataat cccaataatt   3480
 acagcatcaa tcactaataa actaacattg ggaccagcca gattggcaac tgttagaaat   3540
 acatgttcca tttctataca aattctcaaa cttctagttg ccaatttaaa aaagtttaaa   3600
 caaagtagtg gcttaaattc aacatcaaaa ttacccctta taaatacaag tcttaccatt   3660
 aaagggtaaa ggtgtccagt ctggcttgct ggttcttctt ctgtgagaaa agtcactgac   3720
 agccagaggc tcccagcctt tccccagtga aggtccaaca agacacacat gcattttctg   3780
 ctaagaaggt agcaaactct aactagcctg tgttgtgagt gacaattgtg cccctacctc   3840
 ccaacataaa tagatggcaa aaagagttgg actacaagag gaaccgccgg aagcagagtc   3900
 ctatgcattt aaaaaagaat caatttgcta gctgcttcct atacctggag tcagtatgtt   3960
 cagtgtctga agaagactag aaatgccagc cctcagtgtc catgctaaac tggcaggaag   4020
 ttttcatagt cctgaagact gacattcaaa acagaccagc acagcagaag gaaagacaag   4080
 ctcctttctc tctgcaatcc caacgcattt ctaacagcct tcggaattct gagcttggac   4140
 aggctcacga ggatgaagga ggaaaagcag tcccagaagg gagagatttc ctctatgcac   4200
 ttgcaatgcc ctttcccttt tagaggaaac aacccagctg aaagctgaag cttgaataaa   4260
 ggagtttctt tattcatagt cctctctgaa aaagagttaa cagtttcatt ctctcaacat   4320
 agaggctttg ggaattaatg tgtctgtctg gtaatgcaag ttctctaagc tactctccta   4380
 tgacatgtga cctaacaagg aaggcaattt tttcaaatga tataatccta aagactcaaa   4440
 taggaaaaaa tgtgtatttt aaatctggca ttagcttatc actgttcaaa aagtcaacga   4500
 gagctcataa ggaggatttc ttcagctttc cataccctag tcctttcctt ccaacctctg   4560
 tcccacagcc acatactgaa tttataccaa ctttgtttca agttacatat cttttcccta   4620
 ttaggcctat cacacagcac agtagcaatc agaaagaagc cactattatc ttcagggctc   4680
 tccaattcct catccctggg agaatggcct ggatggctct cctgtacccc acactgccat   4740
 ctacatctct atacacgaag gtagctcctg gcacccagtt tagttcctta ggggtagcaa   4800
 caaaagaccc cagcaagtta aaggcaggaa agacaaagaa acacacccta agaggtcaat   4860
 ctacaaaact tgcaaagctg ggtatgtggg aacagtaaaa tgttttaata gctgaaaaga   4920
 tcccagaagg tcaggtacac agtcacatgg gtcaagcagg actcactttc ctaggctgat   4980
 tttgagttcc tttccataat tctgtaatgt gggaagaaat atccaaactg tgaactgagc   5040
 ttcttactag tgtcctgaaa aatatttcct taaaaaagtg cataaacttg tctgagggaa   5100
 ttaagacacc aggaagacca agtgttgatg aggctggaaa aaaaaactgt ccaaataaaa   5160
 ttaagacaca acagattcaa ggatgacttc tgcaggctca tgctaatttg ccagcacagc   5220
 aggcctcccc tattgccttt ggtagcagta tcttttctta aaaaggaggc tggggaatag   5280
 acttcatgaa agatgaggtg gcagatcaac cctagtgctc ttctacttat aaatggtgag   5340
 tctgatggtg gtggtgaaca caggcttatg aacaggacaa cagtaactaa atgactcaag   5400
 tgacaaccac catcacagcc ctaccttctg atttacaact ttcaacaatc atcaaaagtt   5460
 actgcaaact aagtacttta agtctgtgtt ttcttgaatg gggttcagga caaacaggca   5520
 agggcttgac agcacattgg ttatccgagt tcattgcagg agaccccggg ggtggggcag   5580
 ctgagcctca aattccagtt tgcaccacct gctctttctg cttgtccctt ttcccatcca   5640
 actcaataga ttccacaaaa agctctccag gtgctcactg tccctgataa gtatacagca   5700
 gggtgagagg ggcatttcct aaatatccag tttttcttag tcagcttatt ttgtttaaat   5760
 acacaccgcg gaacacttct gatgaagggg ggaaaatgca atttccttaa ctcgaaagag   5820
 ctatttaaaa aaacaaaaca ggaaactccc caaacaaaag tcagcagaac aaaatagaaa   5880
 tactcagagg cttagaataa gactgagcat attagttac                          5919



      <210> 2120
      <211> 666
      <212> DNA
      <213> Homo sapiens


      <400> 2120
 gcttcctcca ctccccaggt tactgccaat gaagaaatta atgttacctc aactgacagt     60
 gaagtggaga ttgtaacagt tggagaaagc tatcggtctc gttcaaccct tggacactcc    120
 agatctcatt ggagccaggg ttcaagttct catgcaagtc ggccacagga gccacggaac    180
 cgcagtagga tttctactgt tatacagccc ttgaggcaga atgcagcaga agttgtggac    240
 cttaccgttg atgaagatga acctactgta gtaccaacca cttctgcaag aatggaatca    300
 caagctacta gcgcttccat taacaattca aatccatcta cctctgagca ggcctctgat    360
 actgcttcag ctgtcaccag tagccaacct tccacagtgt cagagacttc agctactctt    420
 acaagcaata gtaccactgg cacttctata ggagatgact caaggagaac tacatctagt    480
 gctgtaacgg aaactggccc tcctgcaatg ccaaggttac cttcctgctg tccccagcac    540
 tcaccatgtg gagggtcgtc acagaaccac catgcattag gacatcctca tacaagttgc    600
 tttcagcagc atggtcacca ttttcaacat catcaccacc accaccatac tccccaccct    660
 tgtatt                                                               666



      <210> 2121
      <211> 344
      <212> DNA
      <213> Homo sapiens


      <400> 2121
 aagtcactcc tgaaatgtgg atcttgggca attattaact gtcatcactt aggggtagag     60
 agtggccgag gcttatggga tatctcagac ccttcagaag gctacattat ccagaatgca    120
 tctcatttgc tggaagaggc acagttgctg atgaactggt tgagctcatg cttgcctgct    180
 tgcccctgct gcagctggct gggtgggaac aacaagaggc cctgaaagtt gtacaagggg    240
 cagtggggca ggccttcagg tggcagtcgg cccccttctc ctggggtggt ccacatggct    300
 aggcttctaa ccatcagctg gttttacagc tatgctgaga acag                     344



      <210> 2122
      <211> 362
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(362)
      <223> n = a,t,c or g


      <400> 2122
 gcaggagctc gagagaagca tggctcagcg gtgcgtttgc gtgctggccc tggtggctat     60
 gctgctccta gttttcccta ccgtctccag atcgatgggc ccgaggagcg gggagcatca    120
 aagggcgtcg cgaatccctt ctcagttcag caaagaggaa cgcgtcgcga tgaaagaggc    180
 gctgaaagtc tttcctacag tggtcagcac cagctttatc cagcatgaag tcgtggaaga    240
 gtatagccac ctgttcacta tccaaggctc ggaccccagc ttgcagccct acctgctgat    300
 ggctcacttt gatgtggtgc ctgcccctga agaaggctgg gaggtgcccc cattctctgg    360
 gn                                                                   362



      <210> 2123
      <211> 2027
      <212> DNA
      <213> Homo sapiens


      <400> 2123
 agcggccgcc cttttttttt ttttttacat gtgatacctt tttttaatgg cttataattt     60
 tagtttaaaa aaattttaat acacaataac tgtacatatt tatgggggta catagtgatg    120
 ttgcaataca tataacatat agtgattagg gtaattagca tatctatcat ctcaaaaact    180
 tatgtctttg ttttgggaac atgcaatatc cttcttctag ctatttgaaa ctatacaata    240
 ttgttaacta tagtcattct acagtgctac agaacactag gaacttatac ctcctatcta    300
 gttgtaattg tgtattttac aactttgaag taggtgtaat tatccctatt tagactatac    360
 ctgtatgaaa cagaaattat tttcatttta cagatgagga aacagacgca gagaagtaat    420
 ttgtccaaag tccatagggt tgtaagactc ataacaagaa ctacaacttg ggcctatctg    480
 aatcttatac ttctggtact atacttgttc acaggtttga aaagagcttt aatttctatt    540
 atttctcaag aatttgtaat gctttctctt gtcactgtgc tttcaactta gaggagttgc    600
 agttttgata aaagacaaac tgatttagct tctaggtttg ttaaatatgt aattcacagg    660
 tcttctcctt gcttatattt ctacgactgc tttctaaatc taattatttt ataaatagtc    720
 ctgttgcttt aattcacttt ttaccctaac ataattaatc aagtttaact ttgaaatctc    780
 catattttat gtgagaactc ccaaggctat ccacttttat tttcctttgt aaatttattg    840
 ctgctcagcc tatttcatta atggcagctt taattataat attttattat attttcaaag    900
 tgcatgataa tggtttacca gtctggttaa tacatcagag atttctattg tgagctatca    960
 gagatgttac catccaacac atttaccaaa gtgtaattgt tatagacgtc ttaccatgaa   1020
 tttacgcccc aaacatatgt ttaatgggga cgaacagtga catgcctatc tgataattcc   1080
 ctgcacgctg cattatcatc tctatattcc aaaatttcgt cttaagccgt ttagtattta   1140
 acttacagaa gaaagggggt tatcttagat aacttttaat atcctaaggg tattttccaa   1200
 ttcacgatac agggagaaaa gaaatgtgtc caggccctta gaagaaaata ctttgaattt   1260
 aaatgtgaca catacattaa acccgcgtga cacgccaggc aggcggtgga agtcaagtgc   1320
 atttgttttt gtttcatcca ccagggcgat ctctttcaca attctgggag aggcctgttt   1380
 gttcctccac tcccacagct gaagtttggg acaaaagttt gaaaaaatcc caggcacctg   1440
 cggctcctat cgaagccggc gaggagcaca gggtagagcg tctcttccca gttttcagtc   1500
 ttcagatcgc aggcctctcg gacccgcaga gcgagcttca cgctgcagcg cttgagaaat   1560
 aagagctatt ccaaggaggg gccctgggtc ctcactgacg cttcgcaaag gtgtacgtcc   1620
 gcccagggaa ggccggcggc gcagcgacgg cgaggagtcc ccaaccatct tctcttcaag   1680
 cagcagtagc tgggttcggg tacccacccc ccgagccgag acgccagagg ccagagtaag   1740
 aaaatggaag cctgcgcccc aagccaaccg ggattccact tagctccgcg cgggggaacg   1800
 agctctcgcc cactcgccgg aggagacggc cctggactcc caaccccgcc ggcgaaacca   1860
 tgagctccgt ccagcagcag ccgccgccgc cgcggagggt caccaacgtg gggtccctgt   1920
 tgctcacccc gcaggagaac gagtccctct tcactttcct cggcaagaaa tgtgtgggtg   1980
 cgggccgtgg cggtcgggcg ccgccttccc gagctgctgg agaataa                 2027



      <210> 2124
      <211> 873
      <212> DNA
      <213> Homo sapiens


      <400> 2124
 ttttttttta tagtttttac ctactttatc tcattgagtt ggagttttcc cccaacagag     60
 tacagtacat atctgcccat ttttatggag aaggaaatgg aggttctcag agtctgaatc    120
 taagatccca tggtcagtga ttggtacagc taggatgcac acccaggtct tctggctctc    180
 tctctttgct gttatctaac tgagaaattt gggcaaaata gagtaaaggt cttgacatca    240
 gggataacta aagcaccaag gtcattttct acatcaaaac actttagtga agcagctaaa    300
 tccgatgatg tcctctttag ctttggcctt ctctcactgt gtgctgtttg gagaactctg    360
 ttatgttgct ctggccttta actcaggctc agtcttccga aatgagctgc tgccggttag    420
 gagcatgttt tatcacgtcc ctgttgcatc aaatcccagc cactgctttg cttgaaggta    480
 atcttgatat caccctaact gtccaactcc aaatcctaga tgcccataat ttcccttaca    540
 ggctctgcct aatagacaga tgcatatgct ttatatcttc ctccacttac ccacaaatag    600
 atggactgaa aagtagcaga gacatcggag acaaaatttc atttgtaaga agtaatggct    660
 ctatcaacat gggcaagccc tttaatttct gagtttattt ttctgtaaaa ttagtagccc    720
 attttctact tcctagggtt gttatatagg ttagaagcaa tatatttaaa ataccaagca    780
 catggcaggt gtgcaacaaa tgatagctat ttttatgcaa cagatacacc tgcacaggag    840
 ccaaatcctc gtgccaagct tggcgtagtc agt                                 873



      <210> 2125
      <211> 2172
      <212> DNA
      <213> Homo sapiens


      <400> 2125
 atggagggac taaactggtt aagtcttctg gccttcatct ttctcctgtg ctggatgctt     60
 tctgccctca aacatcagac tccaaattct tcagcttttg gactcttgga cttacaccag    120
 tggtttgcca caggctctcg gatgaataaa aacaacaaac cttccagttt catagccata    180
 agaaatgctg ctttctctga agtcggcatt gggatctctg ccaatgccat gctccttctc    240
 ttccacatcc tcacgtgcct tctcaagcac aggaccaagc ccgctgacct gatcgtttgt    300
 catgtggctc taatccatat catattgctg ctacccacag agttcatagc tacagatatt    360
 tttgggtctc aggattcaga ggatgacatc aaacataagt cagttatcta caggcgtaac    420
 aggcagtccc agcattttca cagcaccaac ctttctccaa aagcaccccc agaaaaaatg    480
 gccacgcaga ccattcttct gctcgtgagt tgctttgtga ttgtgtatgt tttggactgt    540
 gttgtcgcct cctgctcagg actggtgtgg aacagtgatc cagtccgtca tcgagtccag    600
 atgctggtgg acaatggcta tgccaccatc agtccttcag tgctacccag gctgactgcc    660
 ccaaacgagt ggagagccag tgtgtacctg aatgacagct tgaacaaatg cagcaacgga    720
 cggctgctct gtgtagacag ggggcttgat gaggggcccc ggtccgtccc aaagtgctct    780
 gagtcagaga ccgacgagga ttacatcgtc ctcagggctc cgctgaggga ggacgaaccc    840
 aaggacgggg gcagtgtggg gaatgcagcc ctggtgtctc ccgaggcctc tgcagaagag    900
 gaagaggagc gtgaggaggg aggcgaggca tgtggcctgg agaggacagg agctggtggg    960
 gagcaggttg accttggtga actacctgac catgaggaga aaagcaacca gaaagtggca   1020
 gctgccaccc tggaggaccg cacacaggat gagcctgctg aggagagctg ccagatcgtc   1080
 cttttccaga acaactgcat ggacaacttt gtgacttccc tcacaggaag cccctacgag   1140
 ttcttcccaa ccaagagcac ctctttttgc agggagagct gttctccttt ttctgagtca   1200
 gtgaaaagct tagaatcaga gcaggcacca aagttggggc tgtgtgcgga ggaggacccc   1260
 gtggttgggg ctttgtgtgg ccagcatgga cccttgcaag atggagtggc ggagggtccc   1320
 acagcccctg atgtggtggt cctgccgaag gaggaggaga aggaggaggt cattgtggat   1380
 gacatgctgg ccaaccccta tgtgatggga gatgaggggg aggaggagga ggaggagttc   1440
 gtggatgaca cactggccaa cccctatgtg atgggagtgg gcctgccagg aagaggaggg   1500
 gaggaggagg aggaggagga ggtcgtggat gacacgctgg ccagcctcta taagatggga   1560
 gaagaacatc gacacaaggg cctggcccca ctctgggaag gtggccagaa accgtcccag   1620
 aaactgcccc caaagaaacc agatctgagg caggttcctc agcccctggc atcggaggtg   1680
 ccgcagagga ggcaggaaag agctgttgtc actgaaggga ggcccctgga agccagcagg   1740
 gccttgccag caaagcccag ggccttcact ttataccctc ggtcgttctc cgtggaaggc   1800
 caagagattc ctgtttccat ctctgtgtac tgggagccag aagggtcggg gttagatgac   1860
 cacaggataa agaggaaaga ggaacatctc tctgtcgtgt ctgggagttt ctcccagaga   1920
 aaccaccttc catccagcgg cacctccacg ccttcttcca tggtcgacat cccacctcct   1980
 ttcgacctgg cctgcatcac caagaagccc atcacaaaga gctctccctc tctcctgatc   2040
 gacagcgact ccccggacaa gtacaagaag aagaagtcat cctttaagcg gttcctggcg   2100
 ctgatgttta acaagatgga gaggccaggc acgatggctc atgcctgtca tcccagcact   2160
 ttgggaagct ga                                                       2172



      <210> 2126
      <211> 685
      <212> DNA
      <213> Homo sapiens


      <400> 2126
 atgcacctgc tgcaagcagc cctactgttg gctgtgccct gccttctctg ctatgttgct     60
 gttggctatg ccttctctgt gctgctgaca ctgctgctga ctgctccggc tcttttgcca    120
 gatgattttg agggcttcaa tataagggaa aaaacaggct ggtatggaaa gaaggagggt    180
 atggtcacat tatcgaatcc acaagttgca agagaaaagg agcagttcaa tgatttgtat    240
 tttaacgcca agcaggctga gcagaagggg tatctgaata ctgctagacg agaagccagc    300
 ctggcattca aagtgacaga gaccacccat aacaagagtg ggttgatcac tgagagctga    360
 ttaggtgctc aggcttccag tggaacattg ttcttcgtag cgagcaaagc cagcgtcctt    420
 tttcgtaggg aagcattctt cttatatgtc agtctcctat ccgtgccatt ttctggtacc    480
 aagacctctg gcatacacta tcttctggca tggcatgtat actaaaactt gtacacgctc    540
 tcagatctta aaatgcagca attatttctc taattagata gttacctatc ttctatgact    600
 tcagtgattg caaattccag cagaagctac tgttctaata agaaaagaat cagaggtctt    660
 aatgcatagt aaaagagtgc ctcgc                                          685



      <210> 2127
      <211> 1036
      <212> DNA
      <213> Homo sapiens


      <400> 2127
 gctactgtag gaggaagaga gatttatgta aagggctttg tccactataa agtccgggct     60
 ctgtttccct gtgagaagcc gcctcggccc accgagatgt cccggcacca tagccgcttc    120
 gaaagagatt accgggtggg ctgggaccgc cgcgaatgga gcgtcaacgg gacgcatggg    180
 accaccagca tctgcagtgt cacctcgggg gccggtggcg gcacagccag cagcctcagc    240
 gtccggcccg gcctcctgcc gctgcccgtg gtgccctccc ggctgcccac cccggctaca    300
 gctcctgctc cctgcaccac cggcagcagc gaggccatca ccagcctcgt ggccagctct    360
 gcgtctgcgg tcaccaccaa ggctcccggc atctccaaag gggacagtca gtcccaggga    420
 ctggcgacca gcatccggtg ggggcagacg cctatcaatc agtccacacc ctgggacact    480
 gatgagccac cctccaaaca gatgagagag agtgacaatc caggcacagg gccatgggtg    540
 accacggtgg ccgccgggaa ccagcccacc ctgatcgcac actcctatgg agtggcccag    600
 cctcccacct tcagcccggc tgtgaacgtc caggccccgg tcattggggt gaccccctca    660
 ctgcctcccc acgtggggcc ccagctcccg ctgatgccag gccactactc gctccctcag    720
 ccgccctctc agccactgag cagcgtggtg gtcaacatgc ctgcccaggc cctgtatgcc    780
 agccctcagc ccctggccgt gtccacactg cccggtgtgg ggcaggtggc ccgcccagga    840
 cccaccgctg tgggcaacgg ccacatggca gggcccctgc tgcctccacc gccgccagcc    900
 cagccgtccg ccactctccc cagtggtgcc cctgccacca atgggccccc cacaaccgac    960
 tcggcccacg ggctgcagat gctgcggacc attggcgtgg ggaagtatga gttcaccgac   1020
 ccggggcacc ccagag                                                   1036



      <210> 2128
      <211> 2097
      <212> DNA
      <213> Homo sapiens


      <400> 2128
 atggaagaga agaccaatgt gcagctccca cctggacaaa cagaacagca tgtggaaatt     60
 cacatcatga acttttgctc caagaaccac cataggatca caccagaaaa accaaaagaa    120
 ctcacagacc cttttaaaga agcagcttgc tgctgcaaac tctatgagat agacaaaaaa    180
 ctatacagaa tggcagaatg gatcaaaatc cacaaaccaa gtatctgctg tcttcaagag    240
 actcacctga cacataagga ttcacataag cttaaggtgt ccatcacctt caaggacttg    300
 gccgtgcggt tctcggagga ggagtggcgg ctcctggagg aggggcagag ggagttctac    360
 cgagacgtga tgcgggagaa ctacgagacg ctggtctctg tggagcctgg aagagctgtt    420
 gggggaggga gccacgctga tgaggggcag gagcctgctg gttgtggaga tccccaggcc    480
 ctggtgcagc tggtgaagga gatcccagag ttcttgtttg gagaagtcaa gggcgctatg    540
 gacagccccg agagcgagag ccggggagcc agcctggatg gagagagagc gagtcccgag    600
 gcagctgcgg caagagagcc ctgccctctc cgaggcctgc tcagctgcct tccagacggc    660
 cctaccagcc agccccacct ggccaccacg cccaccgaca gctcgtgttc cagtggccca    720
 actggtgacg gggtccaggg aagtcctctc cccatcagaa tttctcctgg gaacagcccc    780
 ttgcaaggcc tcatcaactg tctgaaggaa atccttgtgc ctgggccccg gcaccccgag    840
 acatccccaa gcttcttgcc acctctccct agcctgggca cgtccaggct aaccagagca    900
 gacctggggc ctgggagccc gccctgggca gaagcgacca gagagcctgt tctgcctctg    960
 ggtctgcaga gctgtgtgag agatggcccc agcaggcccc tggccccccg aggaaccccc   1020
 accagcttct cctcatccag cagcaccgac tgggacctgg attttgggag tcctgtgggg   1080
 aaccaggggc agcatcctgg aaaagggtct gcccccaagc cctccccgct gcactgcctg   1140
 gagagcgccc tgagggggat cttgcctgta aggcccttgc gcttcgcctg cgtgggaggc   1200
 cccagcccca gccccagccc cggctccagc tcgagcttca gcggctctga aggagaagac   1260
 ccgaggccag agcctgagct ctggaagccg ctcccccagg agagggaccg ccttcccagc   1320
 tgtaagcctc ctgtccctct gtccccatgt cctggtggga cccctgctgg cagcagtggc   1380
 ggcagccctg gtgaagaccc caggagaaca gagcccaggt actgcagcgg cctcggtgca   1440
 gggagtcctg cacattggcc gtgctttagt tccctgtaag gtacagctca ggatccctgc   1500
 ccggtttctc agctggagaa aaggcccagg gttagtgaag catccagagg cctggagctt   1560
 ggacatggaa gacccagagt tgcagccgcc atgccactgt gggaagcccc tgcagcagga   1620
 gctgcacagc ctcggtgctg cccttgcgga gaagctggat cggctcgcca cagcgctggc   1680
 aggcctggct caggaagtgg ccaccatgag gacccaggga gcctctcctc ctgcagccag   1740
 tgcagatgca gacgtgccga cctcaggagt ggcaccagac gggatcccag agcggcccaa   1800
 ggagccgagc agcctgctgg gaggagtgca gagggccctc caggaagaac tgtggggtga   1860
 gggttcccag ggaaggacag gattccagtc cttccaccag cgtggaattg tggccgtgcg   1920
 cccttcttct tgggggtctt gcatactccc tctgactgtg aaatacaaga cttgtctctg   1980
 gttaaaagac atttcaagga tcagaagagg agggacacag acatgcccag agtggaggag   2040
 acccaggaag aaggtgatgg gaggatggag gtagagattg aagtgctgtg tctataa      2097



      <210> 2129
      <211> 728
      <212> DNA
      <213> Homo sapiens


      <400> 2129
 gtccccggct cctgatggag gcggggccgc atccccggcc ggggcactgc tgcaagcctg     60
 gggggcggct ggacatgaac cacggcttcg tgcaccatat ccgacggaac cagatcgctc    120
 gggacgacta tgacaagaag gtgaagcagg cggccaagga gaaggtgagg aggcggcaca    180
 cgcccgcgcc gacgcggccc cgcaagccag acctgcaggt gtacctgccg cgacaccgag    240
 atgtctctgc ccacccacgc aacccagact atgaagagtc cggtgaaagc agcagtagtg    300
 gaggctctga gctggagcct tctggccatc agctcttctg cttagaatac gaggcagaca    360
 gtggagaggt cacatcagtt atcgtctatc agggtgatga cccaggaaag gtgagtgaga    420
 aggtgtcggc acacacgcct ctggatccac ccatgcgaga agccctcaag ttgcgtatcc    480
 aggaggagat tgcaaagcgc cagagccaac actgaccatg ttgaaggcgt tctctccagg    540
 ctggattcac tgcactcgga agaattctgc ccagggaatt tagtgtgggg gtaccaggac    600
 cagtttgtct gatcttgaga cccccagagc tgctgcatcc atagggtgtt gcaggactac    660
 acctggcctg ccttgcagtc cattctttct tatatgttga cccatttgcc cagcctgata    720
 ttctggaa                                                             728



      <210> 2130
      <211> 2338
      <212> DNA
      <213> Homo sapiens


      <400> 2130
 tcctgaattc ccgggtcgac gatttcgtcg gcggcccgcg gcggaccatg gccctggccc     60
 ggcgtcgctg ggctttcctc acggcgtccc cgagcagcgt cgcagagcgg gccgacttcc    120
 gggaaggaac tgaccagcga ctgagcggcg gccggcgcgc ttagcgccct gaacatgcgg    180
 cagtccctgc gggcgacccc gggctccgga caggcggcgg cggaggcggc ggctcgggag    240
 ggaaggaggc ggcggcgccg gcggaggtgg cggcggagac ggccggcgcc cggcgcggag    300
 ccctagggag gcagttcagc gcggcctcgg gcctcgtcga gaaggatgct gtcccgaaag    360
 aaaaccaaaa acgaagtgtc caagccggcc gaggtgcagg ggaagtacgt gaagaaggag    420
 acgtcgcctc tgcttcggaa tcttatgcct tcattcatcc ggcatggtcc aacaattcca    480
 agacgaactg atatctgtct tccagattca agccctaatg ccttttcaac ttctggagat    540
 ggagtagttt caagaaacca gagtttcctt agaactccaa ttcaaagaac acctcatgaa    600
 ataatgagaa gagaaagcaa cagattatct gcaccttctt atcttgccag aagtctagca    660
 gatgtcccta gagagtatgg ttcttctcag tcatttgtaa cggaagttag ttttgctgtt    720
 gaaaatggag actctggttc ccgatattat tattcagaca atttttttga tggtcagaga    780
 aagcggccac ttggagatcg tgcacatgaa gactacagat attatgaata caaccatgat    840
 ctcttccaaa gaatgccaca gaatcagggg aggcatgctt caggtattgg gagagttgct    900
 gctacatctt taggaaattt gactaaccat ggttctgaag atttacccct tcctcctggc    960
 tggtctgtgg actggacaat gagagggaga aaatattata tagatcataa cacaaataca   1020
 actcactgga gccatcctct tgagcgagaa ggacttcctc ctggatggga acgagttgag   1080
 tcatccgaat ttggaaccta ttatgtagat cacacaaata agaaggccca atacacggca   1140
 tccctgtgct cctacgtgta cctcggtatg atcaaccacc tcctgtcaca taccagccac   1200
 agcaaactga aagaaatcag tcccttctgg tacctgcaaa tccatatcat actgcagaaa   1260
 ttcctgactg gcttcaggtt tacgcacgag cccctgtgaa atatgaccac attctgaagt   1320
 gggaactctt ccagctggct gacctggata cataccaggg aatgctaaag ttgctcttca   1380
 tgaaagaatt ggagcagatt gttaaaatgt atgaagcata cagacaagcc cttcttacag   1440
 agttggaaaa ccgaaagcag agacagcagt ggtatgccca acaacatgga aaaaattttt   1500
 gagctgattt tttaaaaatt taagttttgt aagagcttta aaatattttc acagataaaa   1560
 aattgcaaac aagtactctg gttaataaat gctgcttcct ttgtggaaat tataaaattc   1620
 taactttaca tgtattttgt tattagaaat tttcttttat tgaatgagaa aaattagtct   1680
 atcattttaa gagccaatat ggcaaacact ttcaaatact gtatattagg aaactgtttt   1740
 ggtattcttg atggaaaaaa atgcagcgga aatgtcatta tgaacagatg ttaaatagga   1800
 aattattact tgttaacttc ttacagcagt agtaccttct ttaaaaaaaa aaaagaatct   1860
 gcggtatttt tttaaaaaaa aagtttactg ctgtagtgtg aaatattgtc tggaaaggga   1920
 tggtttaaat attaccatga tgtagttgaa atataaaata ggatttggaa ccttattgtg   1980
 ataaatattt atatatgatg tatgtttgtc tcccctctcc aaagtaagga acccagctgg   2040
 gcgtggtggc tcactcctgt aatcccagca ttttgggagg ccgaggtggg tggaccgctt   2100
 gagtccacga gtttaagacc agcctgggca acatggtgaa gccccatctc tacaaaaaat   2160
 acaaaaaaat tagccgggta tgatggtgtg tgcctctagt cccagctact tgggaggctg   2220
 aggtcagagg atggcttgag cccaagaggc agaggttgca gggtcaagat cgcaccactt   2280
 gcactgcagc ctgagagaga gagagccaga ccttgtctca aaaaataaaa aaaaaaaa     2338



      <210> 2131
      <211> 1356
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1356)
      <223> n = a,t,c or g


      <400> 2131
 tttttttttt ttagtaaaca acctagtctt ttatttgccc aaggccggct gttgcaagca     60
 ctgaggcccc aagacttcca gaagggaagg ggaggagggg caaagcactg tgcctaccag    120
 gtgctgcctg ccccgtcctg cttcctgcag gaggtgggaa gggagagaaa acggacattc    180
 gcgccatcaa gtatctcccc agttttcagc cactatattc agttgtggag gaggaaactg    240
 aggcacacgc atccccccag gcttctactt gctagtccaa ggtttaactt actccctccc    300
 ctcatctcta cccccagcag aatgagctgt aagcagcctg gggagggtct caggagccca    360
 tctggtggcc tgtggagcgg ggcaggccag ccagggtcaa gggctagggg tggggggagc    420
 aggaggggtg tggctggagg agcagctgct ggcggtgggg ggagtcggca ctcaataggg    480
 gaccccagct ggggttccat actgatagca gtgggggaca ggcagagccc tcagctgtac    540
 agacagggaa attgaggctg agaagcctcc agtctttggg tagggagggg ccttccttca    600
 gctactcagg tccattcatc ttccccatga agacgctggc tctggggctg gagcgccttg    660
 tcagcggcca ctccatgttt agactgaggt acaaggagtg gaaggcagcc aggtcacctg    720
 gccacagagc ctccttcaac tcttgacaaa ctggagggga accctccccc accacagctg    780
 ctggaaaagg gagtgctggg ctctggcgcc tgtctgcctt ccgctgctca cgtgcttgag    840
 aaaggctcat ttttagcacc tggcctcttt tccctgcctg gagggagctt aggggacaga    900
 gcagggaaga aggcaggcaa gggggacagg gagacctgga agcagggccc aaggggatgt    960
 ctgattgctt cgttctcccc tctaagggtg cccaggccca gagaagggcc ctcagccgcc   1020
 gtgcagagtg gagatgaaga ggacgctgtc ctggtcctga agctggtagt ccagctcacc   1080
 cagtagctcc cagtcggcat cgttaatcag caccagaatt cctggccgca cgctgtctcc   1140
 ctggatgaac aactctggcc gctcttttag caaattcttc ttgatccaga tgagcaggtt   1200
 ccggatgtcc cagggttcct cctgtccagg caaagtgact cgatgtttct taataccgtc   1260
 aaacaggagc tccgcaccac ctccgaactc cacctccact gacaagggcg cagccatgtt   1320
 gaggcagccc ctcgtgccaa gaanggctgt ggcatc                             1356



      <210> 2132
      <211> 3123
      <212> DNA
      <213> Homo sapiens


      <400> 2132
 gtcaggtcca tgagctgccc accgtcctgg ccttactgtg ccccctgccc caccaacata     60
 ggtgaaagca cctcccctct aaggaagacc atagagaccc caacactgtg ggaccccaaa    120
 gctccttcat gctcactgga gctcccaccg tgggtgcttg caagtcctca gcgctcccgg    180
 ggtacagccc tccccttcct gccctctaat gtcctcccct cccttgccct tccctccact    240
 tcctttctct gccgtcccct cctctcccat cttgtgacct ctttactggc ggggcctgga    300
 gcccatgatg gacacttgcg gaaggagggg tggcggagca cccctgagat gacatcgctg    360
 cctgccccag agcaccccgc ctctccctgt gactcagttc tttgcagccc agatgtgagc    420
 atgtgcaccc tgggacctgc tgcccgttgg gatgcccagg ccaaatcagc ccctctgcct    480
 ccatgctgca ctgattgcaa gagtttccca catctgcaga ggccgtgggc tcagccccac    540
 accagccagg ccaccagtgt tgatagcggt gaggcgggga caaagggaat gtctcagttc    600
 acagtgtgga catggtggag gtctcggcct tgcgagacaa ggcaggggga ggggatagga    660
 aattgggggt attctgtgac tcctgggcca ccggggagcc agaatcttcc agccagactg    720
 gatgggcagg gcttagcttc ctgatgccgc ccattcacca ctttcacccc gggaacctac    780
 ctgggcatca tgggaggcag agcctgaacc ccaacccaac cctaactcta atgctaaccc    840
 ctaaaccatc cctcacccta acccaatcct cgccctaacc ctaatgctaa cccctgaccc    900
 gacccaatcc taaccctgat gctaacccct gactcaactc tcaccctaac cctgatgcta    960
 acccctgacc caatcctcac cctaacactg atactaaccc ttaacctaac ccaacccagc   1020
 cctaactcca actctaaagc taactcctaa ccctaggaga ggagcccagg ccgggccctc   1080
 tccctgctgg tttcctgttg ggctttggag ccccagatgc ctgcccagag gcttccttgt   1140
 gcggggtggg gtccagcagt gggggatggg cccagagctg gtgtagccac cagcagagcc   1200
 atcctgatcc acaggaccat ccctggtggg gtggggcccc ctggggcagg aaggccactg   1260
 aggccaggga gactcccagg cccactcacg gcgcaggccc cacaggagct ggctggaggc   1320
 tatgggtgcg gggcgtgggc ctgccggggg ttgcgtgaca ggcagtgggg agtgggttgt   1380
 gctggcagct gtgggtgagt gaggaggctc ctctcatgaa gggccctggg gaagtggaat   1440
 ctggccctga gagacccccg gcctcctctg caggggctgc cggcaggagg ggaaccgggg   1500
 accacctccc gccacagagc ctggggcccc cagccttgcc tacagggagg gtagatgaga   1560
 gtgtaaactg catatgaggt tgggctaaac ctggacatgt gtttcataac caaagcagcc   1620
 aggaatctcc ggctctgccc agtgatcatc tgggcaggac atggggacga gtgtccaggc   1680
 tgaagtcagg gcccggccag cagagggcca ttttgtattg agctccacag ctggtcacat   1740
 tctgtggaat gtgcagacgt gcacggccca tcagacaggg tctggagtgg ggctgccatc   1800
 ttgggcagct cctcccgggt gtctgcaaaa tgcagaggtc accagagcca aggcagcaag   1860
 gcaaggagcc cggcttctaa ggaactctga gcaggtgtgg tccatggctg ggaggcagct   1920
 ggccccacag cacatagcac ggagggcggc gcggagtcct ggacgctctt ggcaggtccc   1980
 ctcatggagg atgtggggga ttggcttagg cctggtctgg ctggccttcc tggaccgcag   2040
 tggccaggag ctgaaaaccg tgaccccagt ctccctgcag ctgttcttga tgggatttct   2100
 gttcgccagt cagatgcatt tgcacaggac ttggatcctg aactgtgtaa cctggagagg   2160
 caggtgtgag cgggccatgc tgctggccca gcctgtgccg gtgtctgttt ctgttgtctc   2220
 tcggcccttc tgtgagccct cagtaaagct cttcgtgctt cagtcagcaa gagtggattc   2280
 tgtcgtcggc aactctgggg accaaacccc gagcctcccc ctcccccaga ccttgcagtg   2340
 ccatggagct gagggacctg tggatccaca gctgtggccc cggaagggct gcaggagctg   2400
 aacctgcgtg agccccgcag agggtgcaga gccggcttgt gcaggctccc agcaggctca   2460
 tgacagcgcg gatggttaaa tgtagctcct gacagccaac tgttaaggtt tcaggcattt   2520
 ttgcaccagg tgacatgatg gtagcctgaa cgtgaccttg gcagcagtct ctacatcaag   2580
 gaaactggca aatgtcaaca tgctgggtac cctcgctcct gccgccgcag gctgtcagtg   2640
 tcttccagcc cacactgcgg ggggccttgt tgtgtggctg cctcccaggc tggggcgagg   2700
 gtctccagag accaccatcg tgcaggctct tggtcaatag cagggtgtgg tgctcctgcc   2760
 aggggacgca ttctccgtgt gacctctaca ccccaggtca ggtcaggatg tgatttgctt   2820
 ctccagggcc gtgactcact agatccacct cccactggtg cctggtggcc cccgacagcc   2880
 ctggccctgt ccaggccctg gcctgtccta cagtcacagg tgctggcctg tccctgctgt   2940
 cctcctgacc acctggtgct cccggccacc ctgcccgccc ccctgtctcc tcgggacagc   3000
 ctggctgcct ccacttgctg gcccctgccg gcccaccctc tttccaagcc tgccctgccc   3060
 ctcagctcct ggggtgggga ggggagacct cgccttctgc ctgcagcgac tcccacctgt   3120
 cac                                                                 3123



      <210> 2133
      <211> 363
      <212> DNA
      <213> Homo sapiens


      <400> 2133
 ttcagatgaa gcacccaggt gtcctgcctt attagaatgc acacagtctc ccaattgagt     60
 gggctttttg taaaattgaa aacctctgtg ggaagtgtgt gtatatgtgt atgtgttccc    120
 aaaataaaaa taatcagctg aaattctcct tcattccagg gcgatggtgt gctagtctga    180
 aaatgtacag caagggccag aggagtctta tgtacccttg caggtaccat cagcggatgc    240
 tgctagtgtc caggtatctt gacactgtgc tgctggactg ggatccccca ggaccactgc    300
 ctgaaggaag gcaacacagt cccggacgca ggcagagaga cctggcatca gcattactgt    360
 gtc                                                                  363



      <210> 2134
      <211> 1107
      <212> DNA
      <213> Homo sapiens


      <400> 2134
 atgttgtact ggcttatgcc taaaggcaaa ttactctgga ttgccagttt cctaaccagg     60
 ctacaaggga tccagcatac tctacccaga gtagaggaaa aatctataca atcagtaaaa    120
 gatgacaata tctaccatcc gcacccaaga cccagaattg ctgtagttgg aagcagctcc    180
 acagtaattt cctatagccc tggggagtat gcttttacca atggcacctc tagatgccct    240
 tcactctctc ttgcagcagg gccaagactg ataacgaatg gcccgtggga agcgcacgaa    300
 gtccaacgtg aatcaacgat agcactaatg aaattgcttc aagttctaga gcagaaggtg    360
 aggctgagag aaggacattc actgggaacc gtcaagatgt caaaaaatat caatcccatg    420
 ggccatgttt ccaatcctcc tacctcctac ccagacgaac tcattacgaa acaggtttgt    480
 cctggatccc atccaaaaag acctggtgaa gtcaagcaca acgaggaggt tcccacttct    540
 caggatagag acacttgtac aacccaagaa acacagtact cagtgagaaa aataatttct    600
 gctgaagatg attttacagt caaaaattac aatcatataa ggaacaagtt cactatacca    660
 tccagaaagg ggcagcaagc ccacagagcc tggctgaata aagccattcc tcagccaatg    720
 ccaacttcag caacttctct gttagcagct cttgttagag ctgcaaagca ccgaaatcaa    780
 cagccccaag acttagctca gtcctcttct catcacatct accttttcat cacaattaca    840
 tttggcagtc ttcgtgattc cgagctgaaa agcaaaagag gccctgaccc tcagctgtcg    900
 ctggagctcg agatggtggc caaggcgaaa gcagtcaagc cggagaactc ccgaaggtgg    960
 ttctcaggta accagctggg ctcaattata aacagcccaa agaaaggctc tgctgtcctg   1020
 gagggcacct ttcaagagaa acaaaaatgg gacgctcgct taacaaaagg ggactgtttg   1080
 gccaccaacg tcctgaacag ggtctga                                       1107



      <210> 2135
      <211> 387
      <212> DNA
      <213> Homo sapiens


      <400> 2135
 atggcctgca gggtcctgca aggtctcccc tttgcctgcc tgtccagccc catctgttcc     60
 cactctgccc ttactcttga tcattctctc ctgtgcctga actttttctt caacccttat    120
 gcccttctgc ctaactttta cttatttggc aagttccagc tcagaattcc ttcctctgga    180
 aagccttttc tgacttccga agaccaggac cctgctggga tctttgagct tgtggaggtg    240
 gtcggcaatg gaacctacgg acaggtgtac aaggtgagac gaatggtgtg gaagtatgac    300
 ctccacatct gcagggcagt cttgggagga gtggaaggaa gtagattcct ggtctgcagg    360
 tctgaagggg gctatgggag atgctag                                        387



      <210> 2136
      <211> 433
      <212> DNA
      <213> Homo sapiens


      <400> 2136
 atgcttttac cgctgttcct tctcattcac accggaatcg ggccaagcta ctcagccagc     60
 gaccgcgcag agccgaggcc ctcgcctggg ggcagattga ctgctcgaat ttggatcaag    120
 ggtgtgaagg aggatggagg gaccatgcaa ggggctgtcg actggggaga gggggttgaa    180
 agatgcgcag gacgcatcac tgcgagccat aaggttgcag acaaatggca ttcgtcacgg    240
 aattccctgg gtggttcgcc cgagcctgga acgccagccc ctggaccgtg ggtgggtttc    300
 tgccatcctt gcctgcccgc ctccccgttg tcctggactg cgaccggaac ggcggccacg    360
 catgcgcagt gtgcggagag ggtccacaac ctctgtcgca gggcaaagcc aagttgagca    420
 aggaggatgt tga                                                       433



      <210> 2137
      <211> 198
      <212> DNA
      <213> Homo sapiens


      <400> 2137
 atgcaggctg gactcgcccg ggccatggtc ctggctgctg gctggtctag ggtggcctcg     60
 gctggggcag ctggcgacac cagtcctgtt ccaagagcct tgtctgatct tcgaatcacc    120
 cagaagtgtg gtctccttgt ccccaaggct gtttcctgga agagcctctt tctgttcccc    180
 atcaccgtgg aactataa                                                  198



      <210> 2138
      <211> 1334
      <212> DNA
      <213> Homo sapiens


      <400> 2138
 ggaattccgg cgggctggac gccgagtgcg gccggcccct cttcgccacc tactcgggcc     60
 tctggaggaa gtgctacttc ctgggcatcg accgggacat cgacaccctc atcctgaaag    120
 gtattgcgca gcgatgcacg gccatcaagt accacttttc tcagcccatc cgcttgcgaa    180
 acattccttt taatttaacc aagaccatac agcaagatga gtggcacctg cttcatttaa    240
 gaagaatcac tgctggcttc ctcggcatgg ccgtagccgt ccttctctgc ggctgcattg    300
 tggccacagt cagtttcttc tgggaggaga gcttgaccca gcacgtggct ggactcctgt    360
 tcctcatgac agggatattt tgcaccattt ccctctgtac ttatgccgcc agtatctcgt    420
 atgatttgaa ccggctccca aagctaattt atagcctgcc tgctgatgtg gaacatggtt    480
 acagctggtc catcttttgc gcctggtgca gtttaggctt tattgtggca gctggaggtc    540
 tctgcatcgc ttatccgttt attagccgga ccaagattgc acagctaaag tctggcagag    600
 actccacggt atgactgtcc tcactgggcc tgtccacagt gcgagcgact cctgagggga    660
 acagcgcgga gttcaggagt ccaagcacaa agcggtcttt tacattccaa cctgttgcct    720
 gccagccctt tctggattac tgatagaaaa tcatgcaaaa cctcccaacc tttctaagga    780
 caagactact gtggattcaa gtgctttaat gactatttat gcgttgactg tgagaatagg    840
 gagcagtgcc atgggacatt tctaggtgta gagaaagaag aaactgcaat ggaaaaattt    900
 gtatgatttc catttatttc agaaagtttg tatgtaacaa ttacccgaga gtcatttcta    960
 cttgcaaaag gattcgtaac aaagcgagta taattttctt gtcattgtat catgcttgtt   1020
 aaattttaat gcagcatctt cagaacttgt cctgatggtg tcttattgtg tcagcaccaa   1080
 atatttgtgc attatttgtg gacgttcctt gtcacaggaa gattcttctt ctgttgcctt   1140
 attgtttttt tttttttaag tctcttctct gtctttgtac tggaatcgaa atcataagat   1200
 aaacagatca aacgtgctta agagctaact cgtgacacta tgcagtattg tttgaagacc   1260
 tgttgttcaa cctctgtctc tttatgttaa ctggatttct gcattaaaag actgccccct   1320
 tgttaaaaaa aaaa                                                     1334



      <210> 2139
      <211> 743
      <212> DNA
      <213> Homo sapiens


      <400> 2139
 ctaaagttct gcatttaggt ctgttctttt ggaaatgcgt gtgtcttcac gtacctgcat     60
 tatcgacacc ttgcagggag cagtgcccac atatcctggt tcagggactc cggcgcttgg    120
 cgagaagtcc ggctctttgg ggctagtggc ttggtctttt ccacgacctg gtgaaagttc    180
 ctctactgcg ccccgcagga gcccctgctg ctgcccttgg tcgccttccc actcctctcc    240
 ggccagcttc ccgcctctgc ggccctctgc cccagccacg cgtgccccca gagagggctt    300
 gccaactcct gcgtctagag cccactttcc cggggcgacg gctataccca agacatctgg    360
 actcctaatc gccaccgcta gcctctgctg ggggcaaacc caccaaccgt gcccgttacc    420
 cctagcccgc ttccttggga agcgatagag tggaacaact cgacgtccga gctgttgacc    480
 cttcccctgg gggtccgggc gtcgaagccc atcagcatat ctgcggtcac aaaacacttc    540
 ttctttctgt cgcttctcat tcagactatt gataagatca tttggtggaa tctgtttgag    600
 acccatgtaa tattgactta aaacggattt tggtactgtt tcatctaaga ttgtctgaaa    660
 caatctgtta ttagcatcac ggcttgaatc tctcccatat gttctttttt tttctttact    720
 tgctttaaag cccatttgta tgc                                            743



      <210> 2140
      <211> 1083
      <212> DNA
      <213> Homo sapiens


      <400> 2140
 gcttgcggcc gccagcgtgg ggatgtctag gagctcgaag gtggtgctgg gcctctcggt     60
 gctgctgacg gcggccacag tggccggcgt acatgtgaag cagcagtggg accagcagag    120
 gcttcgtgac ggagttatca gagacattga gaggcaaatt cggaaaaaag aaaacattcg    180
 tcttttggga gaacagatta ttttgactga gcaacttgaa gcagaaagag agaagatgtt    240
 attggcaaaa ggatctcaaa aatcatgact tgaatgtgaa atatctgttg gacagacaac    300
 acgagtttgt gtgtgtgtgt tgatggagag tagcttagta gtatcttcat cttttttttg    360
 gtcactgtcc ttttaaactt gatcaaataa aggacagtgg gtcatataag ttactgcttt    420
 cagggtccct tatatctgaa taaaggagtg tgggcagaca ctttttggaa gagtctgtct    480
 gggtgatcct ggtagaagcc ccattagggt cactgtccag tgcttagggt tgttactgag    540
 aagcactgcc gagcttgtga gaaggaaggg atggatagta gcatccacct gagtagtctg    600
 atcagtcggc atgatgacga agccacgaga acatcgacct cagaaggact ggaggaaggt    660
 gaagtggagg gagagacgct cctgatcgtc gaatccgagg atcaggcatc agtggactta    720
 tcgcacgacc agagtgggga ttccctcaac agtgatgaag gagacgtgtc ttggatggag    780
 gagcagctgt cctacttctg tgacaagtgc caaaaatgga taccagccag taaggagctt    840
 ctcaattcct ttgatttgtc aattcctgtg tgaaggtttg tttttccaac ctgtgaaaga    900
 aacgtgaatg taaaagagac ctaaataaaa ggataattat atttattctc taggttgatc    960
 agctattaaa tttatataaa acataggcat gtttgtacta atgaaacgta ctgtcaacct   1020
 ctatcacatt gttaaattaa cacttttggt ggtaactcaa taaaattgag aaaattggaa   1080
 aaa                                                                 1083



      <210> 2141
      <211> 455
      <212> DNA
      <213> Homo sapiens


      <400> 2141
 actacaaaac atattttatt acaaagcact aaatacaatg cggataatcc cagactcaag     60
 acgtaattat tccaacacat atcctccagc agaagcagtt tccgagggga aaaccgaagc    120
 ctatgccttc cttcttccag gaatacgaag cggcccttgc ccctgtaggc ttcgtcctta    180
 ggttcccgtc atgaaggtaa tcagaagggt ttctttttca gcccaaagac ggtgacgaat    240
 aaagccattt cagtgacagc tggaagggca tgaatgtcct gcttgtcata ctcctcgggg    300
 gtgaacgtga gaggcaggca ggcctgtatg ttgctgtccc gggaccagaa taaggtgatg    360
 acgaccacca gatgcgccag gagcgtcagg aagcgagagg gcacaagccc tgagacccgg    420
 cccatggccc tcggggacaa gggcggcggt ctctg                               455



      <210> 2142
      <211> 806
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(806)
      <223> n = a,t,c or g


      <400> 2142
 cgtacccctg tggaggaatt cctcccaacc accttaacca agtcagcccc tcccacatag     60
 tccctagtta agatcagaat gagctttatc tgcttcttaa actttgttgt tcctacctct    120
 gcaatccctc ttaggctatg gaactactgc gggatgaatt caccaagccg cagctgggac    180
 tgcctttgta ctcctctctc tagacagtct gccccagtct cacacatggc caaagtctgg    240
 taggtagttg ctgagttcct gagtgttgct ctctgggcca aggcagtaca gggcaacttc    300
 ccaaggcaga gcagacagga gtagtgcttg gatttggatc agaccacact gggctttgct    360
 gagaggaact gggccagcat acagaatggt ttttaatgga ctgggtttga aacagttctc    420
 agagtgttga gagcaattat gaaggaatca gagtggctgt ggatgctgag aggtttggag    480
 gtccctaaag gtatccccca atctgtactg cagaattgga accccgctga caagaagaga    540
 actagaggag gctggagcag gcgttgccct ccagtgcaag gggttgcacc tcacagggct    600
 gaagctgccg aaggctaggg acaccggccg ccaccaacaa cttggagctt ctgcttcctt    660
 ccctcgaagg ggggaggggc cccgttagga ctcgcgcgcg aggcttgcac tttgtacccg    720
 gggacccacc cccccccccc ccaaattcaa ngatataaat actgcaaccc ccgtctcgcg    780
 cccttcaccc gcccctatgg aatagc                                         806



      <210> 2143
      <211> 1610
      <212> DNA
      <213> Homo sapiens


      <400> 2143
 gcctcctcct cagctcgcct ggcttctcac ttaggcgtgt gctttcgctt tgcagcaaaa     60
 gctgctgctt ttcgcatcta aattcttgct ctgaaggtgc caagaacctg gaaaccggct    120
 gggagtgggg tctcaccagc ctttggagac cctcctgagc cgtctggcaa ccagtgacga    180
 tacagagctg cacggaacgt catgaaggac caacgcctgg ttttccatag taaagttagg    240
 tcatctggtt atgcgtcagc accacatgta actatgtttt caccaaagac caacatcaag    300
 agtgagggga aaggatcttc aaggagcagg agcagctgcg cacgggaggc ataccccgtg    360
 gagtgcgctg tgcccaccaa gcccggcccc caggtcgctg ccgcccccac ctgcacacgt    420
 gtatgctgca tccagtactc aggagatggg cagtggctgg cctgtgggtt ggccaaccat    480
 ctgttactcg tttttgatgc cagcctgact gggacacctg ctgtgttttc aggtcacgac    540
 ggggcagtga atgccgtgtg ctggagccag gaccggaggt ggctgctctc tgcggcccgg    600
 gacgggaccc tgcgaatgtg gtcggctcgt ggggcagagc tcgcactgct tctgatataa    660
 acagaagagc aagtccaagc tgatttgcag gctctccacg acgggtgcag tagacatgac    720
 cagtttatcg gcagtcaacg acttttattc ccacatcgta ctcgcagctg gccggaacag    780
 gaccgtggaa gtgtttgacc tcaacgccgg ctgcagtgca gcggtgatag tggaagccca    840
 ctcacggcct gtccatcaaa tctgccaaaa taaaggttca tcatttacaa cccaacagcc    900
 tcaggcttat aaccttttcc tgaccacggc cattggcgat gggatgagac tgtgggacct    960
 gagaaccctg aggtgtgagc gccactttga agggcatcca acccgcggct atccatgtgg   1020
 aatcgctttc agtccttgtg gacgattcgc ggcttgtggg gccgaggaca gacacgctta   1080
 cgtgtatgaa atgggctcaa gcacgttttc tcaccggctg gctgggcaca cagacactgt   1140
 cactggagtg gccttcaacc catcagcgcc ccagcttgcc acagctacct tggatggtaa   1200
 actccagctc tttctagctg agtaaccact gacctgtgag ctgggtccag gaatgctgtg   1260
 aggaacaact taaaagtaag aagtagtggt tcatccatca gggggccaga agcagcaact   1320
 gtttttcata ttttgagact tgcctcagat ttcccccgtt tgcaagctcc tcccctctgt   1380
 gtgtgccatg tcagagtttt atgtctttct gctcctcaaa agggatcccc cttcattggg   1440
 aaaatggaaa tggcgtccag tacttctgca cagaatttgg taaagttaaa acaaaatatc   1500
 tttcaataaa acataatata gtatttgttt gataattaga gttggaagaa aaaagagaga   1560
 atttcttttg ggcagtgaaa ataaagcagt taacagtcaa aaaaaaaaaa              1610



      <210> 2144
      <211> 911
      <212> DNA
      <213> Homo sapiens


      <400> 2144
 agcgcgccca tacatacgga ggctgtaaaa ccttgaggag attcatcttg caggctctcc     60
 ttccatcaag tctctcctcc ctagcgctct gggtccttaa tggcagcagc cgccgctacc    120
 aagatccttc tgtgcctccc gcttctgctc ctgctgtccg gctggtcccg ggctgggcga    180
 gccgaccctc actctctttg ctatgacatc accgtcatcc ctaagttcag acctggacca    240
 cggtggtgtg cggttcaagg ccaggtggat gaaaagactt ttcttcacta tgactgtggc    300
 aacaagacag tcacacctgt cagtcccctg gggaagaaac taaatgtcac aacggcctgg    360
 aaagcacaga acccagtact gagagaggtg gtggacatac ttacagagca actgcgtgac    420
 attcagctgg agaattacac acccaaggaa cccctcaccc tgcaggccag gatgtcttgt    480
 gagcagaaag ctgaaggaca cagcagtgga tcttggcagt tcagtttcga tgggcagatc    540
 ttcctcctct ttgactcaga gaagagaatg tggacaacgg ttcatcctgg agccagaaag    600
 atgaaagaaa agtgggagaa tgacaaggtt gtggccatgt ccttccatta cttctcaatg    660
 ggagactgta taggatggct tgaggacttc ttgatgggca tggacagcac cctggagcca    720
 agtgcaggag caccactcgc catgtcctca ggcacaaccc aactcagggc cacagccacc    780
 accctcatcc tttgctgcct cctcatcctc ctcccctgct tcatcctccc tggcatctga    840
 ggagagtcct ttagagtgac aggttaaagc tgataccaaa aggctcctgt gagcacggtc    900
 ttgatcaaac t                                                         911



      <210> 2145
      <211> 515
      <212> DNA
      <213> Homo sapiens


      <400> 2145
 cccacgcgtc cggcttcatc tgcccaccaa gttttaaatt gtaagaactg agcaggagtt     60
 agacaagctc gagtaagagc atcccagtca gtaggaatca tccaactgga aacagcaaca    120
 ttctttaaca gtcccattac aaaaggagaa cctggtccat actgattaac agcttgttta    180
 aattctttaa ataatttaaa aggaaaaggc tcaaatgtaa ctataatatt tccctgttga    240
 tctggggggt gtattctaac agggaattgc caagcctcta aatcgccctc tcatctagct    300
 tgctgaattc ctgcctgaat agaactaaga gcagttgctc aaggcattgc tcagtcactg    360
 gggcaactac ttttcaccca atgtcctctg gaaaagaaag atctggaggg tctttttctt    420
 caaaataata aggagggggt gcagaagggt agggatgaac ctctccctcc tttgccgctt    480
 gagctttagc tggcaaattg gcaaataaac ctgct                               515



      <210> 2146
      <211> 1339
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1339)
      <223> n = a,t,c or g


      <400> 2146
 tttttttttt ttgattctta acatatttaa tgaaactcga gcttcataaa ccagtgaaat     60
 gcctacccct atggagacgg ggagctggtc atgggaccca ggtgcctgga ggacatccca    120
 gtggctttga aggctccagc cagtcaagac ggtcaatatt agcccttctg ccaacatctg    180
 gcaatgtgag gctggggtgg acgttggcct gatgttgcca ggagtaggat gctgatgctg    240
 ccagagagta ggtgggctcc aaaccccagg cttctcactt gcttactaag cacagcagtc    300
 tgaagcttgg gacctgggca gtgcgtcttt ggagaaggca aaaaagccac agcagcaaca    360
 cttaggagca agacccttcc cgctctccac cctatttcct cccctgaaga agagcaacag    420
 ctcaagctct agcatggcac agaacgctag gttgggccag gcaagcagcc atggtggggc    480
 caggtgaagc aatgtgggtc tcagcaagga acccctctga aggtggcagt ggctcccagg    540
 gctgctgcac actggacacc acaactttgg catcagctgc atggtgagct gcagagtggt    600
 cagaggggct ggggccctgc caagagagca aggccagacc tgcccagcgg gaggcaggaa    660
 ggccctgatc cagcaaggag aagtagagga agtccacagc cacctctgtt actcatcgct    720
 actgggacat ctggggacag gctctgttct tgggagagca ggtcaccagg atttgtaggg    780
 ctgcctgccg gtgacagaca cgtaagtcac agggaaaggc cgggatccag gcctcagctg    840
 tagcagcagc tgtctgtcgg tcaggatccc cggctctggg cgcttccaag atgaagccag    900
 aaggatgtag agcaccagca gcccaaaggc caccaccagc atcccggtgc tgttggcaaa    960
 gaccgcctca ctgggcaggc tgtggtatgg cctggtggtg tttttcaaac tgaagaaaag   1020
 cttctcatta atgcccgaaa tgacggatgc gatggacaga gagaggatgg cggctccaaa   1080
 aaagacgtgg ataggtttta ggaggctgcg cagccacatg gacgcccagg gcaggaggaa   1140
 gacagcaaag cccaggaacc tctggcaggc gaagaggaag acagtggtga tgcccagcca   1200
 gctgtgaagg gagtagaggt tggcagtcct tccatggttg tgaaacgtaa agacagcaac   1260
 cagccccaca acagtgagga cgaaggccgn nttccncaag gtnctcaaag atctcagttn   1320
 nnnnnnnnnc ggnactcct                                                1339



      <210> 2147
      <211> 470
      <212> DNA
      <213> Homo sapiens


      <400> 2147
 gacaagtcga cgagatttcc gagtacgtct atagtcagcc ttgtgacatt tgatgttcta     60
 caatgaaccc gtcggagatg caaagaatag cacctccacg gagacagaga caccgcagtc    120
 gagcaccatc ggctcacaag atgaacagaa tggtgatgtc agaagaacag atgaagttgc    180
 catccaccaa gaaggcggag ccgccgacat gggcacaatt aaagaagctg acacagttag    240
 ctaaaaaaaa gcctagagaa cacaaaggtg acacaaactc cagagaacat gctgcttgca    300
 gctttgaaga ctgtatcaac agtgtctgca ggtgtaccca gcagctccga agagagcgac    360
 catcgagaac gagccatgat gacaacggtg gttttgtcga aaagaagggg gaaatgtggg    420
 gaaaagaaag agatatcaga ctgttactgt gtctatgtag aaagaagtaa               470



      <210> 2148
      <211> 939
      <212> DNA
      <213> Homo sapiens


      <400> 2148
 atggcgctca ggcttgtaat cccagcactt tgggaggctg agctggtggg ggcactgatg     60
 ctggccgccc tctcccacct gcaccgattt ctgctctcta tgtgggttct accacctggc    120
 accttcacag acgccttccc cgggctgctg tttcattttc ccagaagaag ccaaaaagac    180
 tgcctccttg gcctttccaa gtctgaccag cgggccatgg cttgttactt tgggatcctt    240
 ttaatagtct ctgccacact gtgttttgga atgaattact acttggatga atttgcaaat    300
 ctgttagacg aacttctgat gaagattaat ggtttgtccg acagcctaca actccccctt    360
 ctggaaaaaa catccaacaa cacaggggag gcaaggacag aagagagtcc cttagtggac    420
 atttctagtt accaagctgc tgagatggtg atgatggcca ggacactggc cacctgcctg    480
 cagcatgccc agggcctggg ctttgaggct tgtcttccca tcctgagtgc tccacatgct    540
 ttatctcact ggaccctcac aacatgcctt tggcagctag gctttatgag tgcggttctc    600
 atcctcaagt acacccgggc actccttgct caaggccagt tctcggggcc atttgtgatt    660
 gacaaaggag tgaggcttga gctcatcggt ctcatatcca gagtctggga agtctctgag    720
 caagaaaact cgaaggagga agtctatcga catgaagaag gaattacagt catctcagat    780
 ttattgttgg gcagacagtg gcaacaggga cacaagggca tctgccttca gctcatgttg    840
 cccttctctc gtgggaaaca cagaaccagc ggagcctttt taatgttcag tcttgagctg    900
 ttcacagtgg cccagcttgt tccaatttcc gggtcctga                           939



      <210> 2149
      <211> 842
      <212> DNA
      <213> Homo sapiens


      <400> 2149
 gttttgaacc cccttggaaa accttgacat gacacgccag cttggcacga ggagggttac     60
 cccttcccta ctgctcctcc tgtggatcca tttgccaaaa tcaaagtgga cgactgtgga    120
 aaaactaagg gatgctttag atatggcaaa ccaggctgta atgcagagac ctgtgactat    180
 ttcctcagct accggatgat aggggctgat gtagaatttg agctgagtgc agacacagat    240
 ggttgggtag cagttggatt ctcttcagac aagaaaatgg gtggtgatga tgtcatggcc    300
 tgcgtccatg atgacaatgg cagggtccgc atacagcact tctataatgt aggccagtgg    360
 gcaaaggaga ttcagagaaa ccctgccaga gatgaagaag gagtttttga gaacaatcgc    420
 gtcacctgca gatttaaacg ccctgtgaat gttcccagag atgaaacaat tgttgatctg    480
 catttgagtt ggtattatct gtttgcttgg ggtccagcca ttcagggctc tatcactcga    540
 catgatatag actcaccgcc ggcttcagag cgtgttgtca gtatttacaa gtatgaagac    600
 atttttatgc catcagctgc ctatcaaacc ttctcatctc cattttgttt gcttctgatt    660
 gttgctctga ccttctacct attgatggga accccctaac cacagctgca gggccaacag    720
 attacatgga ttgggaagtc tttagtataa atatattttt taaagaatat ccagtataat    780
 tttagcttca attatttaag aaaaaaaacc tcatataatt tcagcttttt ggaagaaaga    840
 ac                                                                   842



      <210> 2150
      <211> 801
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(801)
      <223> n = a,t,c or g


      <400> 2150
 tttttattta tttattttat ttttattttt tgtattttta gtagagacag ggtttcacca     60
 tgttggccag gctggttttg aactcctgac ctcaagtgat ccatccgcct tggcctccca    120
 aagtgctagg attacaggca tgagccacca tgcctggcct aatttttgtc ttcttagtag    180
 agaccaggtt tcgccatgtt ggccaggctg gtcttgaact cctgacctca ggtgatccac    240
 tttcctcggc ctcccaaagt gctgactaca agcgtgagcc accgtgcctt ctgcaggaga    300
 gcctcagtgt gggcagtgag caccaggtgg gagcccagac ccgcgtagtg ataggccagc    360
 tcctcaccaa caccagcgtt ggcccctgtc agcagcactc gcgctccctg gaggctggct    420
 ggccatagcc ggggtggtca ctctgggcgg aggacaggac agctggcccg gtttctccct    480
 ccctcaaccc caggtgctca cctgggtcga agttgtcatc ccaataatag gcgaagaaca    540
 gggcccccag ccctgtgagg agaagcacct tcatggtcct gtgtgggcct gcagagggac    600
 aggggacaga ggtggccggc acaggcctgg cccacagcca cccgtgtttg gtgggtgttt    660
 ggtgatgcca ccgccttgga tccacgcctt cctatccacc tccacagcca ccacctgtcc    720
 aggccaccac ggtggctcca tgaaccaccg cggctccata nccganttgc nccncgctgg    780
 ataggngatc gatggtcgaa g                                              801



      <210> 2151
      <211> 3320
      <212> DNA
      <213> Homo sapiens


      <400> 2151
 ggcacgagcg gcacgaggcg gcgggagggg aaacgtgcgc ggccgaaggg gaggcggagc     60
 ccgcgccggc tgcgcagagg agccgctctc gccgccgcca cctcggctgg gagcccacga    120
 ggctgccgca tcctgccctc ggaacaatgg gactcggcgc gcgaggtgct tgggccgcgc    180
 tgctcctggg gacgctgcag gtgctagcgc tgctgggggc cgcccatgaa agcgcagcca    240
 tggcggcatc tgcaaacata gagaattctg ggcttccaca caactccagt gctaactcaa    300
 cagagactct ccaacatgtg ccttctgacc atacaaatga aacttccaac agtactgtga    360
 aaccaccaac ttcagttgcc tcagactcca gtaatacaac ggtcaccacc atgaaaccta    420
 cagcggcatc taatacaaca acaccaggga tggtctcaac aaatatgact tctaccacct    480
 taaagtctac acccaaaaca acaagtgttt cacagaacac atctcagata tcaacatcca    540
 caatgaccgt aacccacaat agttcagtga catctgctgc ttcatcagta acaatcacaa    600
 caactatgca ttctgaagca aagaaaggat caaaatttga tactgggagc tttgttggtg    660
 gtattgtatt aacgctggga gttttatcta ttctttacat tggatgcaaa atgtattact    720
 caagaagagg cattcggtat cgaaccatag atgaacatga tgccatcatt taaggaaatc    780
 catggaccaa ggatggaata cagattgatg ctgccctatc aattaatttt ggtttattaa    840
 tagtttaaaa caatattctc tttttgaaaa tagtataaac aggccatgca tataatgtac    900
 agtgtattac gtaaatatgt aaagattctt caaggtaaca agggtttggg ttttgaaata    960
 aacatctgga tcttatagac cgttcataca atggttttag caagttcata gtaagacaaa   1020
 caagtcctat cttttttttt ttggctgggg tgggggcatt ggtcacatat gaccagtaat   1080
 tgaagcacgt catcactgaa agacagaatg ccatctgggc atacaaataa gaagtttgtc   1140
 acagcactca ggattttggg tatcttttgt agctcacata aagaacttca gtgcttttca   1200
 gagctggata tatcttaatt actaatgcca cacagaaatt atacaatcaa actagatctg   1260
 aagcataatt taagaaaaac atcaacattt tttgtgcttt aaactgtagt agttggtcta   1320
 gaaacaaaat actccaaaaa aaaaaaaatt tttcaaataa aacccaaaat taatagcttt   1380
 gcttaggccc tgttagggat ccattgggag cattaaggga gcacatattt ttattaactt   1440
 cttttgagct tttcaatgtt gatgtaattt ttgttctctg tgtaatttag ggtaaactgc   1500
 agtgtttaac ataataatgt tttaaagact tagttgtcag tattaaataa tcctggcatt   1560
 atagggaaaa aacctcctag aagttagatt atttgctact gtgagaatat tgtcaccact   1620
 ggaagttact ttagttcatt taattttaat tttatatttt gtgaatattt taagaactgt   1680
 agagctgctt tcaatatcta gaaattttta attgagtgta aacacaccta actttaagaa   1740
 aaagaaccgc ttgtatgatt ttcaaaagaa catttagaat tctatagagt caaaactata   1800
 gcgtaatgct gtgtttatta agccagggat tgtgggactt cccccaggca actaaacctg   1860
 caggatgaaa atgctatatt ttctttcatg cactgtcgat attactcaga tttggggaaa   1920
 tgacattttt atactaaaac aaacaccaaa atattttaga ataaattctt agaaagtttt   1980
 gagaggaatt tttagagagg acatttcctc cttcctgatt tggatattcc ctcaaatccc   2040
 tcctcttact ccatgctgaa ggagaagtac tctcagatgc attatgttaa tggagagaaa   2100
 aagcacagta ttgtagagac accaatatta gctaatgtat tttggagtgt tttccatttt   2160
 acagtttata ttccagcact caaaactcag ggtcaagttt taacaaaaga ggtatgtagt   2220
 cacagtaaat actaagatgg catttctatc tcagagggcc aaagtgaatc acaccagttt   2280
 ctgaaggtcc taaaaatagc tcagatgtcc taatgaacat gcacctacat ttaataggag   2340
 tacaataaaa ctgttgtcag cttttgtttt acagagaacg ctagatatta agaattttga   2400
 aatggatcat ttctacttgc tgtgcatttt aaccaataat ctgatgaata tagaaaaaaa   2460
 tgatccaaaa tatggatatg attggatgta tgtaacacat acatggagta tggaggaaat   2520
 tttctgaaaa atacatttag attagtttag tttgaaggag aggtgggctg atggctgagt   2580
 tgtatgttac taacttggcc ctgactggtt gtgcaaccat tgcttcattt ctttgcaaaa   2640
 tgtagttaag atatacttta ttctaatgaa ggccttttaa atttgtccac tgcattcttg   2700
 gtatttcact acttcaagtc agtcagaact tcgtagaccg acctgaagtt tctttttgaa   2760
 tacttgtttc tttagcactt tgaagataga aaaaccactt tttaagtact aagtcatcat   2820
 ttgccttgaa agtttcctct gcattgggtt tgaagtagtt tagttatgtc tttttctctg   2880
 tatgtaagta gtataatttg ttactttcaa atacccgtac tttgaatgta ggtttttttg   2940
 ttgttgttat ctataaaaat tgagggaaat ggttatgcaa aaaaatattt tgctttggac   3000
 catatttctt aagcataaaa aaaatgctca gttttgcttg cattccttga gaatgtattt   3060
 atctgaagat caaaacaaac aatccagatg tataagtact aggcagaagc caattttaaa   3120
 atttccttga ataatccatg aaaggaataa ttcaaataca gataaacaga gttggcagta   3180
 tattatagtg ataattttgt attttcacaa aaaaaaagtt aaactcttct tttcttttta   3240
 ttataatgac cagcttttgg tatttcattg ttaccaagtt ctatttttag aataaaattg   3300
 ttctccttct aaaaaaaaaa                                               3320



      <210> 2152
      <211> 381
      <212> DNA
      <213> Homo sapiens


      <400> 2152
 ttgggtattc tccagtccaa ttacagctcg tgatgcgttg ggtattaaac acaccatggt     60
 gaagattcgt cccttgtcac aggccacaag agcagccaag gccaaagcta gagcttatgc    120
 tgagttcctc cagccagcaa aggagcgtcc tgagacttca gcagccctag ccagaaggtt    180
 agtcatcagt gcccttgggg ttcgaagtaa gcagagcaaa accgaacgag aagcagagct    240
 caagaaactg caagaagcca gagagagaaa gcggttggaa gccaagcaac gggaagacat    300
 ctgggaaggc agagaccagt ctacagtttg aacatcactc aatgaaaggg ataattccat    360
 gaatcagaaa atgtttccat t                                              381



      <210> 2153
      <211> 867
      <212> DNA
      <213> Homo sapiens


      <400> 2153
 atggggccag aatatcagac tgaaaaaccc agactgtggc ctggagcatg ttttcagtgc     60
 ctgtctttgc tgcctgtgct gttgggtaga accatccagg cgggcagcca ggttatgaga    120
 ggtgaagcct tgcccgtggt gatactgcct gcaaaggcca gagccaggac cgacccaggt    180
 ctgacaccaa aacccatgct ctttcgattt ggggtaaaat ttcaaaacca gacatatgtc    240
 ttcgtgctcc agctggccaa acctggtgcc atggaaaatc cagatgcttg cttacctggc    300
 aggccgtgct ggatctgcta cctggggcca gtacaagcaa ttgagtattc ctatgctatc    360
 cttggaccct cagttcagga aagacagagg gaagaaagag ggaaggggtg ggaagaggaa    420
 ggaagaaagg aagaacgcac taatccctgt attaaaggta gctggcaccc tatggtgttt    480
 gcattcttgg aaactacctg ccacgtagtg aggaagccca ggcacccagc agagaaggtt    540
 ccctgtgatg ctgctgctgc tgctgctgcc tctgctttgg gatccacagc tctaaaggaa    600
 cccacagtgc aaacagcgac aaatggccat ttgatccttg acttcagcca tgtccttccg    660
 gcagtccaaa gcagcatacc acccagcggc cagcccagag agaagggctt ttctgtactg    720
 catggggcta ggcgaaggct tgagcagagc agacaggctg ttccatctcc caacaggcca    780
 caacagtttc actggattcg tccagtggct gaatctgcac ggtctgctcg actactgctt    840
 gatgctcgat tgacgctgat gctgtag                                        867



      <210> 2154
      <211> 517
      <212> DNA
      <213> Homo sapiens


      <400> 2154
 tcatgttatg tttgcggagg aaccgtaaca ggagatcaat ggccatagga agcccgagaa     60
 ttagttccca cagacccagt tcctgatgaa ttcccagccc aaaagaacca ccctgacaat    120
 ttttaggttc taaaagtctc aattattaga cagtattgca cagctattga aggaaaacaa    180
 ttcactcatt ctataggacg gcttagttgt cttaggcaaa agctgtataa tggtaccaca    240
 aaaacagtta catggtggaa ttccaattac acagaaagaa atccattcag taaatttcca    300
 aagttgcaga ctgtttgggc ccacccagaa ttccactggg actggatggc ccccaccagg    360
 ttatactgga tatgtggaca cagagcttat gctaagctgc ctgatcagtg gacaggtagc    420
 tgtgtaatta gcaccattaa gccatctttc ttcttactgc ccataaaaac aggtgaactt    480
 ctaggcttcc cagtctatgc ttcccacgaa aaacgaa                             517



      <210> 2155
      <211> 407
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(407)
      <223> n = a,t,c or g


      <400> 2155
 atttttagtg gagacggagt tttgttatgt tggccaggct ggtcttgaac tcctgacctc     60
 cagagatccg cccgcctcgg cctccaaagg tgctgggatg acaggcgtga gccaccaggt    120
 ccagccccag taatgatctt gactttggac atagcaagca gtgtagaagc agggacgtcc    180
 ttcggtttgt cttttctttc ttccagctgg gctctgtctg cccaggaggg ctgcttggct    240
 gtgccttctg tgggtcacga gggctcctgg ttggagctct tctgctgtgg accaagcctt    300
 ctccccagct gtcacctgtg cctgcatctc agcgtctgtc ctctctttcc ctaatgccgc    360
 ccctccccca accccagcat ttgacacaca cgtccataga aaccctn                  407



      <210> 2156
      <211> 2262
      <212> DNA
      <213> Homo sapiens


      <400> 2156
 cctgccactg aggcaggtgc ggccccagga ccatcaccag gaatgcgagc ccaccctgga     60
 ccagaggtag gagcccaagg tccggcccct tgctctttga ttgtgggcag cctcctgccc    120
 tctctgggtc tcagttgccc catctgcaga gcgaggaggc ccgggctggt tggtcttgaa    180
 ggcccttttc catgccgaca tcatgtcact ctaggcctgg ggttcagttt cctgtggctg    240
 gtgatgctgt ggttaagttt gcttgacccc agcagcccga gggactgtct gagtcacagc    300
 acagccccta ttgcgtggct gctggtgtgt ggggtcagtt ccagcagatg aatgtgtcat    360
 gtggcacacc ttgtcccttc ccgcagcatt tcctggttcc ccccagaccc ttgagcgctc    420
 tttgggaccc agaaggagtc cttgcacagg gaaggcttga ggtgagaagc cgcttcccag    480
 actgtcaggg ccaggcctgg gtctagaatt cttgctgctg ctttgcagag tcaacagccc    540
 atcagcccat gttttagagg ggacactttg gtcctcggtt cccaccctca gcaagcaggc    600
 ctccagcccg aggaaggcct ctgccgtggt gacgttgccg tgtggggctg cgtggctgtt    660
 ccccttggct ggagcattca gccaacccca gcgtcccccc tgaggcgttc attggcagcc    720
 ccctaggact gcacgctggc cccacggtaa ccccccctcc cccaccaaca tcctgcaggg    780
 atggggtcag tggttccacc ttcacaggcc actttgaagg gtggattctt tgaggcccct    840
 gccagtcggc tccctgctca gctgctggcc cgggcgacct gggactcagc accaacggct    900
 gaagtttctc agctgggctc tgacctgggg tctggggcag ggaacgaaca tggtggcttt    960
 gggctgagag gatgagggag gtctttccca ggtcaaatta ctttcctttg gcctctgcct   1020
 gaggctcgat ttgcctctct ggtccaatgg gactgacact gttgtacaac ctgacctgtg   1080
 gctgagggtg tctgggctta agcatgtgga ccccttcggt gtgtctggcc ttcctccatc   1140
 gtcctgccct ttggcctttt ggtttgaagc cacaggtgtg gcttctggcc ttagcagatg   1200
 gtatgcttgc ggaccgcagc ccagcatgcc ggtgggccca cagcccgagc cagcccagag   1260
 ctgccggaag ggccgccctt cccggccctg gcggggtgct ggacactggc cattttcact   1320
 agagtttgcc tggcagggac cgatctctgc cccctcctct ccccaggcct ctggctgcag   1380
 tgatgccgca gaatcctgag ccaggtgcct cctgagcagc ccgtgcgcct ctccacagcg   1440
 gcgtttgcca cccaatgcgg ctcgcttcag atgctctgat gcagagggca tgcccatagt   1500
 ccctctgcag agcctcgcac tggggccagg gcaggcacca gccccaggcg gccagtcggc   1560
 cacggcctgt cctcttcctc gtagcgtctg ctcctcactt tgtgttgatg gtgacttagg   1620
 agaatgttcc gattttccat gatctaagca ggccacgttt aaaataacat caaggcaagc   1680
 gtacgtgtca ccctctgtac tgacatctcc tcccctgaaa tgcttttcag tttgacagcc   1740
 cgtttcctag acaagtgcac ctggggtttc aggaactttg tgttttttcg gagggggttg   1800
 gtggggaggt cgggatgcct gggatccctt cctggagagg caggctgtct ctggaaaaag   1860
 cctccattgc ccacccgcca ggcggaaagt caccctgttc ccagcgcggt ttcagcattt   1920
 aattttaagg gagctaagga agcgcggcgc gccccctggt ggtggtaagc cgccaacgca   1980
 cctgggggct gcaaccccac cggacgggtg gtccggaggg aggctggagc ggggaggcga   2040
 ggagggggct gtgagtcctc agaggccctg ggccaccaca tttctggcag cgtttcccag   2100
 acacccctct gctaggccat ccctggatag caagtgaatt aacttaaggg cactgtgatg   2160
 ggaagccttg cccccctctt tttttttttt ttttaaaaat gggggaaaaa accccagggg   2220
 ttaatttttg aatgaataaa aggtttttgt tgaaaaaaaa aa                      2262



      <210> 2157
      <211> 402
      <212> DNA
      <213> Homo sapiens


      <400> 2157
 atggatggcc aggcgcgatg gctcacacct gtaatcccag cactttggga ggccgaggta     60
 tttattgagc atatgttgta tgccctcaac attttaagaa ctgtacttgg acgtgcacgc    120
 accctgtccc tcaaccaccg ctgccgcctc cttcttctgt cactcctggt gctgcactgt    180
 gttcgttcag tgagaagctg gtacctcttt tgtgaagcgg cagctgagaa gactctggca    240
 tttgccatgg ccgaggaaaa gcccaaggca ttgtcaatgg ggcagatcag attccgattt    300
 gacagtcagc caatcaatga aacagacaca cctgtacagg tggaaatgga ggatatagat    360
 ataattgatg tgttccacca gcagatagga ggtgtctact ga                       402



      <210> 2158
      <211> 1644
      <212> DNA
      <213> Homo sapiens


      <400> 2158
 atgggtgaac tgcatatgat cactgaggaa aagcaccagc ccttcatgga cactcagaca     60
 gcagcaaagg gaacactgct tgaggcgggc cctggcctgg acccagtttg tttgggacat    120
 attaagaaag taatccagag gaaattttgg aggtactcag cacctggcac tgttcctacc    180
 acctctgcta ttcctggtga gactgagtgg ggcagactcc cacagtggtc tactgcatgg    240
 agtgaaacag cacaacatgg gtggccagct gccaggcagt caagaattac cgtgctacat    300
 cagcaacccc agtgtgaccc tggacctgaa gtaacatctg agcaactacc aggtgtcata    360
 aatatgttga ctcttaaata cattaaggtg gctgcccacc cccatggttc ttggaacact    420
 cgtgtgccct gcttggttgc tgtgttgtta acacctaccc ggctttccta ctacatctct    480
 gaaatacaaa ctaccttcag agaatactat aaacacctct atgaaaataa actagaaaat    540
 ctagaagaaa tggataaatt cctggacaca tacaccctcc caagactaaa ccaggaagaa    600
 gttgaatctc tgaatagacc aatgacaagt tctgaaattg aggcagtaat taatagcctg    660
 ccaaccaaaa aaagcccagg accagatgga ttcacagccg aattctacca gaggtacgaa    720
 gaggagctgg taccattcct tctgagacta ttccaaacaa tagaaaagga gggaatcctc    780
 cctaactcat tttatgaggc cagcatcatc ctgataccaa aacctggcag agacacaaca    840
 aaaaatgaaa atttcaggcc aatatccctg atgaacattg atgcgaaaac cctcaataaa    900
 ataatggcaa accgaatcca gcagcacagc aaaaagctta tccaccacaa tcaggttggc    960
 tttatttctg ggatgcaagg ctggttcaat atatgcaaat caataaacat aatccatcac   1020
 ataaacagaa ccaatgacaa aaaccacatg attatctcaa tagatgcaga aaaggccttt   1080
 gacaaaattc aacacccctt catgctaaaa gctctcaata aactaggtat tgatggaaca   1140
 catctcaaaa taataagagc tatttttgac aaacccacag ccaatatcat actcaatggg   1200
 caaaagctgg aagcattcct tttgaaaacc gacacaagac aaggatgccc tctctcacca   1260
 ctcctattca acgtagtatt ggaagttctg gccagggcaa tcaggcaaga aaaagaaata   1320
 ccggcccctg cagatacctc tagcctcatt gctcaccatc catctccttc atatcagccc   1380
 tggaccccag taacacgaac cagccacagc actcccacca tcacctgcta cccctgcctg   1440
 gaatgcaccc cagccaaatg gttgacatct gtctccacaa tggggggtgg actgttatct   1500
 gttcctcagg ggactgtgag ggtctctgct ctgaactact gctttatccc ccagctcgga   1560
 ggagggcccc tcatggcatc aagtgccagc agtgactatg ttccagagtc tgatgaaagt   1620
 gagcctcttt tcacctttga ataa                                          1644



      <210> 2159
      <211> 411
      <212> DNA
      <213> Homo sapiens


      <400> 2159
 atgggcttct ctagccctgg cccttcccgc gggacgtcca gcctcctcct ctcggcgtgg     60
 ctgattgctc ttcctccttc gtctgttgca cgtggaaggt cggagggcgt ggctgtgaag    120
 ctcccgttcc tcctcatggc attgattgct gtccccttcg cacccgctga ccgcgccccc    180
 gccgcgcccg ccgcgcccgc cgccgaccag ggctcctggt gcctgtgcca gctcaatggg    240
 gccgccgacc tcgaagtttc cgaaggacct caccctgccc ggggacgcgg ccctcgggtg    300
 cgggactccc gcgactggag gagagggcgc gtcttcgcgg gccagaagcg agactcagag    360
 agcccgggca ccgaccccgg ggcggtcctg gggcagggct ggctctgcta g             411



      <210> 2160
      <211> 650
      <212> DNA
      <213> Homo sapiens


      <400> 2160
 gccgatttgc ctgttctcac gccccaccct cagacctagc cggagcaaag tttcacttat     60
 agaagggaga ggagcgaaca tggcagcgcg ttggcggttt tggtgtgtct ctgtgaccat    120
 ggtggtggcg ctgctcatcg tttgcgacgt tccctcagcc tctgcccaaa gaaagaagga    180
 gatggtgtta tctgaaaagg ttagtcagct gatggaatgg actaacaaaa gacctgtaat    240
 aagaatgaat ggagacaagt tccgtcgcct tgtgaaagcc ccaccgagaa attactccgt    300
 tatcgtcatg ttcactgctc tccaactgca tagacagtgt gtcgtttgca agtatgaact    360
 ccaactacgc tttaaaatta aataactcat ataacgttaa ccatttctca atcccagaag    420
 ggccaagtta gtgcagtagg tacttaaata atgtgtatac cttactcagg atgtctatgg    480
 tagcaatact actgctcttt tatagtcaat tcttgattat ccgtatcagt gggggaagca    540
 tggataaata attgtggtag ccatcataaa agtaacttaa agatcaaaca gtcatcttat    600
 aaattagtat caacttggcg gggcatgggg gctcatgcct gtaatccccg               650



      <210> 2161
      <211> 764
      <212> DNA
      <213> Homo sapiens


      <400> 2161
 tcccgggtcg aggatttcgt gctgcacttg ctccgggcgc tggcgcaaga tgatgttgtt     60
 ccatatttta aaacggagcc aggcctacca cagatccacc tggaagggaa ccgccttgtt    120
 ctcacctgcc ttgccgaagg gagctggcct ttggagttca agtggatgcg cgatgacagt    180
 gagctcacca cctacagcag cgaatataag tacattattc catctttgca gaagctcgat    240
 gctgggtttt accgctgcgt ggtgcgaaac agaatgggag cactcctgca aagaaaatca    300
 gaagttcaag tcgcatatat gggaagtttc atggatacgg accagaggaa aacagtttct    360
 caaggacgtg cagcgattct aaacctgctg cccatcacca gctaccccag acctcaagtg    420
 acttggttta gagaagggca caagattatt ccaagcaaca gaatagccat cacattggag    480
 aatcagctgg tgatcctcgc caccacaacc agtgatgccg gggcatacta cgtgcaggcc    540
 gtgaatgaga aaaatggaga aaacaagaca agcccattca ttcatttgag catagcaagc    600
 ttttgtggaa acaccacaca agattgagga aaatttgtaa aaactttctg gccagcgttt    660
 ctgaaaaatc aaaagatatt acagccaatt atcatttaat gaagatacat ttttgcttgc    720
 tgtcgggaga ataaagcagg gaacctttat gtagtgaaaa aaaa                     764



      <210> 2162
      <211> 1060
      <212> DNA
      <213> Homo sapiens


      <400> 2162
 gtttggggtt cggctgccgg gaagaggcgc gggtagaagc gggggctctc ctcagagctc     60
 gacgcatttt tactttccct ctcatttctc tgaccgaagc tgggtgtcgg gctttcgcct    120
 ctagcgactg gtggaattgc ctgcatccgg gccccgggct tcccggcggc ggcggcggcg    180
 gcggcggcgg ccagggacaa gggatgggga tctggcctct tccttgcttt cccgccctca    240
 gtacccgagc tgtctccttc ccggggaccc gctgggagcg ctgccgctgc gggctcgaga    300
 aatgggagcc tcggatatct ccggagcgtt tggataatgt gacagttgga atgcagtgat    360
 gtcgactctt tgcccaccgc catctccagc tgttgccaag acagagattg ctttaagtgg    420
 caaatcacct ttattagcag ctacttttgc ttactgggac aatattcttg gtcctagagt    480
 aaggcacatt tgggctccaa agacagaaca ggaaagacaa gaaaatgtcc agaagattat    540
 cttagaaggc acagagagaa tggaagatca gggtcagagt attattccaa tgcttactgg    600
 agaagtgatt cctgtaatgg aactgctttc atctatgaaa tcacacagtg ttcctgaaga    660
 aatagatata gctgatacag tactcaatga tgatgatatt ggtgacagct gtcatgaagg    720
 ctttcttctc aagtaagaat ttttcttttc ataaaagctg gatgaagcag ataccatctt    780
 atgctcacct atgacaagat ttggaagaaa gaaaataaca gactgtctac ttagattgtt    840
 ctagggacaa cattacgtat ttgaactgtt gcttaaattt gtgttatttt tcactcatta    900
 tatttctata tatatttggt gttattccat ttgctattta aagaaaccga gtttccatcc    960
 cagacaagaa atcatggccc cttgcttgat tctggtttct tgttttactt ctcattaaag   1020
 ctaacagaat cctttcatat taagttgcac tgtagatgag                         1060



      <210> 2163
      <211> 474
      <212> DNA
      <213> Homo sapiens


      <400> 2163
 cactggtccc accatcaaga atatggatgg cacatttaat gtcactagct gcttgaagct     60
 gaactcctct caggaagacc ctgggactgt ctaccagtgt gtggtacggc atgcgtcctt    120
 gcataccccc ttgaggagca actttaccct gactgctgct cggcacagtc tttctgaaac    180
 tgagaagaca gataattttt ccattcattg gtggcctatt tcattcattg gtgttggact    240
 ggttttatta attgttttga ttccttggaa aaagatatgt aacaaatcat cttcagccta    300
 tactcctctc aagtgcattc tgaaacactg gaactccttt gacactcaga ctctgaagaa    360
 agagcacctc atattctttt gcactcgggc atggccgtct taccagctgc aggatgggga    420
 ggcttggcct cctgagggaa gtgttaatat taatacatat tcaacaactg tatt          474



      <210> 2164
      <211> 2210
      <212> DNA
      <213> Homo sapiens


      <400> 2164
 gtccggactt cccgggtcga cgatttcgtg gcggggacgc catgcgagcc agcgtctccc     60
 ttctctcctg gacagaatgc cgtgtcctgg gacttctctg atggcgagag gctgcggctg    120
 taccaggaag aaacatattg ccgagtggat gccgccgcgc agcgtgtttg cttgaggcag    180
 aagcttcagc atctgctggg ataactggag gaagaaatat gaagccttag cggctttacc    240
 cgggaagcga gtttcgagat ggcggctcag cggatccgag cggccaactc caatggcctc    300
 cctcgctgca agtcagaggg gaccctgatt gacctgagcg aagggttttc agagacgagc    360
 tttaatgaca tcaaagtgcc ttctcccagt gccttgctcg tagacaaccc cacacctttc    420
 ggaaatgcaa aggaagtgat tgcgatcaag gactattgcc ccaccaactt caccacactg    480
 aagttctcca agggcgacca tctctacgtc ttggacacat ctggcggtga gtggtggtac    540
 gcacacaaca ccaccgaaat gggctacatc ccctcctcct atgtgcagcc cttgaactac    600
 cggaactcaa cactgagtga cagcggtatg attgataatc ttccagacag cccagacgag    660
 gtagccaagg agctggagct gctcggggga tggacagatg acaaaaaagt accaggcaga    720
 atgtacagta ataacccttt ctggaatggg gtccagacca atccatttct gaatgggaac    780
 gtgcccgtca tgcccagcct ggatgagctg aatcccaaaa gtactgtgga tttgctcctt    840
 tttgacgcag gtacatcctc cttcaccgaa tccagctcag ccaccacgaa tagcactggc    900
 aacatcttcg atgagcttcc agtcacaaac ggactccacg cagagccgcc ggtcaggcgg    960
 gacaacccct tcttcagaag caagcgctcc tacagtctct cggaactctc cgtcctccaa   1020
 gccaagtccg atgctcccac atcgtcgagt ttcttcaccg gcttgaaatc acctgccccc   1080
 gagcaatttc agagccggga ggattttcga actgcctggc taaaccacag gaagctggcc   1140
 cggtcttgcc acgacctgga cttgcttggc caaagccctg gttggggcca gacccaagcc   1200
 gtggagacaa acatcgtgtg caagctggat agctccgggg gtgctgtcca gcttcctgac   1260
 accagcatca gcatccacgt gcccgagggc cacgtcgccc ctggggagac ccagcagatc   1320
 tccatgaaag ccctgctgga ccccccgctg gagctcaaca gtgacaggtc ctgcagcatc   1380
 agccctgtgc tggaggtcaa gctgagcaac ctggaggtga aaacctctat catcttggag   1440
 atgaaagtgt cagccgagat aaaaaatgac ctttttagca aaagcacagt gggcctccag   1500
 tgcctgagga gcgactcgaa ggaagggcca tatgtctccg tcccgctcaa ctgcagctgt   1560
 ggggacacgg tccaggcaca gctgcacaac ctggagccct gtatgtacgt ggctgtcgtg   1620
 gcccatggcc caagcatcct ctacccttcc accgtgtggg acttcatcaa taaaaaagtc   1680
 acagtgggtc tctacgggcc taaacacatc cacccatcct tcaagacggt agtggaccat   1740
 ttttggggca tgactgtgcc cccaaagacg ctcctggggt caggcgaggg tcacacgcca   1800
 ggcacccaac cctgccccgg tggccctgca gctgccccag gatctcaagg tctgtatgtt   1860
 ttccaatatg acgaattacg aggtcaaagc cagcgagcag gccaaagtgg tgcgaggatt   1920
 ccagctgaag ctgggcaagg tgagccgcct gatcttcccc atcacctccc agaaccccaa   1980
 cgagctctct gacttcacgc tgcgggttca ggtgaaggac gaccaggagg ccatcctcac   2040
 ccagttttgt gtccagactc ctcagccacc ccctaaaagt gccatcaagc cttccgggca   2100
 aaggaggttt ctcaagaaga acgaagtcgg gaaaatcatc ctgtccccgt ttgccaccac   2160
 tacaaagtac ccgactttcc aggaccgccc ggtgtccagc ctcaagtttg              2210



      <210> 2165
      <211> 462
      <212> DNA
      <213> Homo sapiens


      <400> 2165
 tttcgtggaa tgagcggttg gctcgggctg gtttcctccc tccaccgcct gcttgtttcg     60
 ccatgcccgg gccggacggt ggggctgcag cggcgaaagc gactgaagtc cgggagcagt    120
 cgcatgagct tcccggtcac caggaggccc cgggaacaga cacctcaccc tgacattgtg    180
 gcagctatac catctggaac agatgacttc caaggacacc gtagcaaaga aaaagagaac    240
 tggaagccca tgtgccttaa tcgcttcatc ctagaggaat gtatagctgc tgatgatttt    300
 cgaattcgtg gtctggaacc caacccacaa taccttcaag gaaagcccac ccaagtctca    360
 gagtctctga ggcttttgcg aaatgacact caggatccca acatcaaaac caggtacatc    420
 atgaatcttg caaaaacaat ccagagaagt cctgacaagt ag                       462



      <210> 2166
      <211> 531
      <212> DNA
      <213> Homo sapiens


      <400> 2166
 atgattatca tccctaaaaa cctcaacatg tgtgctcttc agagcaaacc agaatctaga     60
 ggatttggag aactgtcaca aagaggaaat gtaaaattca atgttgagac cttgtgcagc    120
 catcagaaaa aaatatcaag actttctgct gccatacatc agctagatat atcagatatt    180
 cgaccactca cggtgttgct gactctttgt ataacattgg cacttctgat gaggggggca    240
 caacccggga tgaactcagg caagattcca tacagaatgt ttattcctaa tagccatagt    300
 gactcagaac tcatgtcatt ccaagatagt gtaagacaca ggcgaggtgg ctttcaaact    360
 tttgactgtg actcacagca agaaacattt tggacctgga gcattggtaa gcgtcacact    420
 gccaaagtga gagctgctgg agaactcata atcccaggaa cgcctcttct actctccgag    480
 taccccagtg accagagtga gagaagctct gaacgagggc acgcggcttg a             531



      <210> 2167
      <211> 789
      <212> DNA
      <213> Homo sapiens


      <400> 2167
 atggggcgcg agcgcgatcc gagcggctgg acctggctgc tccgctgtgc cgcggccgct     60
 tgcgccctac ttctgggctc ccagcgccag gaaacccagc tgctcctctc ggagcactcg    120
 gaccctgaca ttgagcaccg agttagggga gaaccaaaaa ggactaccag gtggttaggt    180
 gttgagtgtt ggaggcaagg agtaattaac attgagacaa aagctcaaga acaactccag    240
 cccaagggga aaaaggtttc cagtcttttg accgcgcttc cggggtctat agatgagctc    300
 agtttgaaac gagatgtaaa ggagtcgatt tctttgccgg cggttccctt ccaaattgag    360
 ttacttctta taagcaaaat taatatgcaa acaagactgc tgcagctgcc gctgaaattc    420
 gctgtggccg ctgcctcttc ccgctttaat cccagacctc cagtcattgg gcagctcctc    480
 agaggcaaga agtcaacacc atggcaaccc gacaagccta tcaaatcacc ggctggcgtg    540
 acagcagcaa cactgcaggc aggagtgggc tgggcggaag agcagagtgg ccactgcgct    600
 caggtacaca gtctgggagt ggacagcagc tgctggtctc cacgttctgg ctacacatat    660
 gtgcaccacc cagtccatac ccctacctta tgtgccctag taggttctgg aggagaaagg    720
 ggaggaggag aaggagagaa gcatataggc ttggaggaac aggaaccgca gaaaagagtt    780
 ttaaactaa                                                            789



      <210> 2168
      <211> 5729
      <212> DNA
      <213> Homo sapiens


      <400> 2168
 gcttcatgac agatgttaac agctggctgc tcacctttgg attccagcta cacaacgtga     60
 tccctggtta tcccaaacca gacatggatg ccatggaacc ctcctacgag cttatccaca    120
 cacagatgaa aacgcaggag tgggacaaca gcaagtctat cctcggggta cagtgtgaag    180
 tacagaagca gctcaaggcc tttgtcacct tagaacggtt tgaccagctc tatggctcca    240
 caatcaccag ctgccagcag gctccaaaga ccaagaagtt tgcatccagc ggctcagtct    300
 ttggcaaggg ggtcaagttt gccttgaagg atggccgagt gaccacagac atcatcagtg    360
 tggccaatga ggatgggcga agggttgctg ccatcttgaa ccatgcccac tacctagaga    420
 acctgcactt caccattgat ggggtggata cccattactt tgtgaaacca ggaccttcag    480
 aaggtgacct ggccatcctg ggcctcagtg gggggcggcg aaccctggag aatggggtca    540
 acgtcactgt gtcccagatc aacacagtac ttaatggcag gactagacgc tacacagaca    600
 tccagctcca gtacggggca ctgtgcttga acacacgcta cgggacaacg ttggatgagg    660
 agaaggcacg ggtcctggag ctgtcccggc agagagccgt gcgccaagcg tgggcccgcg    720
 agcagcagag actgcgggaa ggggaggaag gcctgcgggc ctggacagag ggggagaagc    780
 agcaggtgct gagcacaggg cgggtgcaag gctacgacgg ctttttcgtg atctctgtcg    840
 agcagtaccc agaactgtca gacagcgcca acaacatcca cttcatgaga cagagcgaga    900
 tgggccggag gtgacagaga ggaccaagga cttcttgcca aagacagcta ctcttttgtg    960
 gccgcatacc tgactgtgtt gtacttttaa aaaaatgatt ttttaacaag tgcagaaaca   1020
 aaaagatact ggttgcattg taactcatgc aacatccttt tttttagaaa agaaaaacac   1080
 agatttggcc ttcgcacatt ttttgcaaag aacagaaggt atttttttct gttagtgtga   1140
 tcacaatgaa aactttattg gtcttttgtt ccctttttcc ttgaggattt ttcccttgtc   1200
 gtttggggta tgtatctcct ctctgagatg catctcctgg gttgtgtcct cgtctgtccc   1260
 taggtaccca gtgtgatgtg ggacatgaat gtctgtgcta acttgtctca tgtgcaaccc   1320
 tttcttcttc gactggggtc gggcaggagt aaagggagtg atgggccagt acaacacccc   1380
 ttccaagggg gcctgggagg agggtctgta ggacctgagg ctccttggca gggctcctgc   1440
 agaagagtgg tggatttctt ctcaccttgt tctctgcctc cagaggatca tagatggctt   1500
 catcttgctc cagggaattt catggtgttg ttcagcacct tttttaagct gccccaaact   1560
 cctgttcaag ctttctattt tgatgctgaa tgaaaccccc taccactttt gcaaatcctg   1620
 tgtagttgtc ggtgccaccc ccatgctggg atagagaaag tgtctcccag gtcctttccc   1680
 ccagaccagt gacataacat cctgggctca gagtcccatc ctcccgggag ggaaagcacc   1740
 caggatgcct gtgattggtt ggtcctccat gatgttcctg ttcatctcct cccttctccc   1800
 aaagccagat gtgagaacga gcactgcaca gcaagccttc aatgtgggca ccatgtccac   1860
 agaacagaag gccacccatg gcaaaggcat ggcagtggtg gcgagggcac cagcctgcct   1920
 tccgaggcaa agccctctct ctatgacttt gagtatcttc cctccaccac tcagccgcca   1980
 ccactgagac gtaggaatgt ggagggaggt gcttggtggc ctttgattct ggaaaaatgc   2040
 ttaacaaaaa aagccagcca aagagaggaa ggcataagct aagcatcctt ctaaccagtt   2100
 cccaaagtcc catctgcctc catgtaccag ctgatcgcag agctggactg gggcaggctg   2160
 ggcttccagg aaattcctga agttctgaaa cagcttcccc tctagagaag cccacccaat   2220
 gtgtttttta gtgacaggaa gaaaggaggg aagagctgat gtggtgtggc ctgcccatat   2280
 catacaaccc caccaggagc agggcagttc ccaaggtggg tgcccgtaga tctgggaggc   2340
 caggctggca tgattcctgt gaagaactgt gcctgtgtcg tcagggagag gcctgagccc   2400
 tctcagaagc agggacagcc cacacctgaa gagcacgccc aagctgaggc agcagccagc   2460
 aggctggggg agcagtgagg gcagggggag tcacagccag agctgggagc cccttgttca   2520
 aggattccat tcctggttca tccgcctaat taccattgtc attaccactc acaggaggct   2580
 ctgggagatg ggaggggaag ccaaatgctt ccttttaagc tgggcttctt agaaaatgga   2640
 acttttatgg gttacattta cattaagtgt ggaaaatgaa ttctgagtct gagctattcc   2700
 ccgtggaaaa ccttgttgga ctgataagct catggcacct ctatagcctt actcacatag   2760
 tcttcagaat attacacaag ttaatgaaac tgagaaggtc tgactgcatg aggatcggag   2820
 cagcatgtag tctgggttct gcctggcaga gggaggcaac caaaacttct tggggagaag   2880
 agatttcgcc ttaacgtcat cccactggga ttagaggatg tgtttcgcta agtgctcttc   2940
 ctgtttccaa aaaaaaaagc caccctgctg cagcagtgcg ctttggcctg cttgtccact   3000
 ggttgcccat tgcccctgga tccagagctt tactgagtca gatacagtgc tctgcaggcc   3060
 tgctgtggga ggcatgagct ggagatgggg gctcccatct ggcaggatca ttcttggatg   3120
 agaatggaaa acagtttggc ctgaagaaca caagttttgt cctccagaag ggacttacgc   3180
 ctctcaaaat gtactcttca taccaagggc ccttgggcaa agtgctcctg cccagttgat   3240
 cagtcccatc ctggctgcct gacatcagtg aagacctgct ggggatgtct gctcagaggt   3300
 caggaacggc atgcggtcca caggaaccag ctccctacgc ttcccccacg ccctgtccct   3360
 cctccacagc cccctcccca aaggaatagg gtggactttt agggatcaaa aacagaatta   3420
 ttgggtgttt catttctttt tttctttctt tctttttttt ttcatagaga tggggtctca   3480
 ctatgttgcc caggctgttc tcaaactcct ggcctcaggc gatccacctt ggcctcctga   3540
 agtgctgggg ttacaggtgt gagccactgc gcctggactg agtgtttgtt tctttaaagg   3600
 atcttatatt tttcctgtgc tacataccac cacagcagcc cagcttctgt ggggagagaa   3660
 gttgaaggat cccgaagctt tagaaaaagg atctcagctg tggcacaggc agtgttatgc   3720
 gcctcactgc cacattggtg ctgttgtatt gaaggtggtg cttctggcct tggccctttt   3780
 gagttggttt ccatttgggc tgcaggtgac tcagtgactc cctcctcaag ctgtcctcct   3840
 gctaagacca gcagtcacaa acccatggca agggtgagtg tgaaggccta accctgtgcc   3900
 tatgtaatag gctccaagca tcgactccca tcctgagagg accggccctt ttgacactca   3960
 ccaaccaaat ctgttcattc gatagagtga ccaggcctcc ctcacctgcc caggtgtatg   4020
 atcctacagt tcctgccttc tctcctaccc cgcacagctg ccaactggtc ctacatcctc   4080
 agcccctctg ccaccacctt aaataggact ttaactgatt ccccaacttt gtttttttgt   4140
 aggatgagat ttccttttta tcccaccccc ccacacccca aacagaacat tgctggaggg   4200
 cagactggag gaaggggaag gcatgcaggt aaattactgc cttgtcagcc tctgaccctc   4260
 atctctcaga attgttggct gagaattaac ccaaggacca caccagtgcc tgatttctac   4320
 ttagggagag aggattggaa acgatcccta agaaactgac tgagggtgag aatggccagg   4380
 aggtgtgtgt ccaaataacc aggagggggc acagaagatg attgcaagcc agaattggca   4440
 attttttttt ggacacagaa caaagaatca gaatttgaaa aaagaagaaa aacaaatctt   4500
 cgcagctgca actttaaagt atcaccttta tagatggcag ggatttccat tatgcaaatg   4560
 gaatctaaga tttcaatgtg aaatcttaga atgcagtttt accacttgca gtcttgtatt   4620
 tgtggtggcc atgtggtgag ggcggtgatg ctgagctttc tgcccaggag gaatgagctt   4680
 tcaagctctc agcagggtgt caggcttggg gatttgacgc atccactgct caaagtccag   4740
 gctattctcc agctctcacg gcagccacta agcccaggag ccagacctgg cccagggaca   4800
 catctcctga gggatcccag aaagaaccca gtctttcctt tcccttgggg ttccttgtta   4860
 gaatgaaaac ctctctattt aaggcacatc attcccagct aggtttatac acttgtctat   4920
 attttactgg aggaaaggga attaaaaaag aactctggca gttcaaggcc cttttcattt   4980
 aaaccttcca aaaacaggca aactcatttt taaaaggatt cattgctgag gtgataggag   5040
 aggaaacctt atcctctcca accttttaca ttcacaaaaa ccatccttgt gtacttgact   5100
 gccctagaca gtggtgactc ttaggtttca ttaccgaatg tggaatatca gagtgtggga   5160
 aggcccaggc gagggccaat gttgtgtttc ttaccccctc tgggaatgcc aaaggcaagg   5220
 tactaggtga cctcctggtc ccccaaaaaa atgtgattta ttctggaggg cgaacagcca   5280
 aagggaggac tagtctggag cacgctcggc cgtcctggca ggagctgagc ctcaggtgct   5340
 ctggcggtgc cccagcagcc ctggattcac cccaacacca gaatcccact tttctaaatc   5400
 ccacctgttg ttctgagcac ctctgaaccc gcagcttcgg caaaaggagt ctgtacccaa   5460
 gctgcttctg gatgaccaac actggagact ctggccttac catgtggaaa tcattttcct   5520
 gaagtctgga actaatcttt gagaagtttc tctctcaaca cttttgtgtt tctcaacact   5580
 gtatcttgac tgtgtaaata ccaacaaggc cgtaaataaa tgcagatgta gataccttct   5640
 agaaaaaaaa aagcataaaa acaaaaccag aagtgatccc gtgtagcctt cgttgacaaa   5700
 taaagactat tttgtgttta aaaaaaaaa                                     5729



      <210> 2169
      <211> 3172
      <212> DNA
      <213> Homo sapiens


      <400> 2169
 tttcgtagcc caacacccgt aaagggtgac tcacaagggc cccagaccca gacagagtcg     60
 gactcgtcgc tgatttcctc agactcttca tccctacagc caaaggaccc gtcattaacg    120
 ccccgcttcc tcagcgactg cgttcaaata cagccccaat caggacgctc cacgcaccat    180
 cggtacacag acccacaggc cgcgagtcca tgcccagaac tcgactcacc cgagcccgaa    240
 cctctccaga caccactggc agcgacaaaa cgccgcatcc acgtccgaaa acgcttccta    300
 ttcagacgcg ctcctgcgcg gactccggga agctgagcga aatcaggaaa attgatgatc    360
 ctctgcagca tcacttgcaa aatcaaagta ttcagaagag tgtgaaacag tgccatgaac    420
 agaatatgtt tggaaatatt gttaatcaga acaaaggtca tttcctgctg aagcaagatt    480
 gtgatacgtt tgacttacat gaaaaacctt taaaatcaaa tttaagtttt gaaaaccaga    540
 aaaggagctc tggcctaaag aactctgctg agtttaatag agatgggaaa tccctttttc    600
 atgctaacca taaacaattt tatactgaaa tgaagtttcc tgcaattgca aaacctatta    660
 ataagtccca gttcattaag caacagagaa ctcacaacat agagaatgcc catgtatgca    720
 gtgaatgtgg gaaagccttc ctcaagttgt ctcagtttat tgatcatcag agagttcaca    780
 ctggagaaaa acctcatgta tgcagtatgt gtgggaaagc tttctccaga aaatccagac    840
 taatggacca tcagagaact catacagaac tgaaacatta tgaatgcact gaatgtgaca    900
 aaaccttcct caagaaatca cagctcaata tacatcagaa aactcatatg ggagggaaac    960
 cttacacatg tagccaatgt gggaaagcct tcatcaagaa gtgtcggctc atttatcatc   1020
 atcgaactca tacaggagag aaaccccatg gatgcagtgt atgtgggaag gccttctcta   1080
 caaagttcag tctcactaca catcagaaaa ctcatacagg agaaaaacct tatatatgta   1140
 gtgaatgtgg aaaaggcttc attgagaaga ggcgtcttac tgcacatcat cgaactcata   1200
 ctggtgagaa accctttata tgcaataaat gtgggaaagg cttcaccttg aagaacagtc   1260
 ttatcacaca tcagcaaact catacaggag agaaattata tacatgtagt gaatgtggaa   1320
 aaggcttttc aatgaagcac tgtctcatgg tacatcaacg aactcatact ggagagaaac   1380
 cttataaatg caatgagtgt ggaaagggct tcgctttgaa gagcccactc atcagacatc   1440
 agcgaacaca tactggagag aaaccctatg tatgcaccga atgtcgaaaa ggtttcacca   1500
 tgaagagtga cctcattgta catcagcgaa ctcatactgc agagaagcca tatatatgca   1560
 atgattgtgg aaaaggcttc actgtgaaga gccgccttat tgtgcatcag cgaactcata   1620
 ctggagaaaa accctatgta tgtggtgagt gtggaaaagg ctttccagca aagatccggc   1680
 taatgggaca tcaacgaact catacaggag agaaacctta tatttgcaat gagtgtggaa   1740
 aaggcttcac tgagaagagt catctcaatg tacatcggcg cactcataca ggagagaaac   1800
 cctatgtatg cagtgaatgt ggcaaaggct taactgggaa aagcatgctc attgcacatc   1860
 agcgaactca tactggggag aaaccttata tatgcaatga atgtggaaag ggcttcacca   1920
 tgaagagtac tctcagtata catcagcaaa ctcatactgg agagaagcca tacaaatgca   1980
 atgaatgtga taaaaccttc aggaagaaga catgcctcat acaacatcag cgatttcaca   2040
 caggaaagac ttcctttgca tgtactgaat gtggaaaatt ctctttgcgc aaaaatgatc   2100
 ttattacaca tcagagaatt cacacaggag agaaaccgta caaatgcagt gactgcggga   2160
 aagccttcac tacaaaatca gggctcaatg ttcatcaaag aaaacataca ggagagaggc   2220
 cctatggatg tagtgattgt gggaaagctt ttgcgcactt gtctatcctt gttaaacaca   2280
 agagaattca caggtagtca ttttgggaaa gcctcttgcc agatgtaggc ccttaagata   2340
 tctgcaaaga agagtaattt catgaatgca gactacatgg ttgtttattt agtgatcagt   2400
 tacttcatgt tttgtgtcag agaaaacatg tacaaaacat ttgagaaaat attttaggac   2460
 attatgtcta aaaattgtat actgagaaaa atcctatgaa tgtggcagac tataaaagcc   2520
 tttggtggga agataaaccc cctcagaagt gatcatagat catgaataaa ctactaattc   2580
 gtggaaatgt aataattata ggaacgtctt tgcccaaaaa taaaacctca acagattgag   2640
 agagttcaca ctggagaaat actttcctct ggcagtgaat gtggcagggt tttcagtaaa   2700
 atgttttgcc tcatcgtgtg ctaggaaata atgcagaaaa aaactaatga aaacattcaa   2760
 tgtagaagac ttttaggaaa acaacagaga atttaatgaa ggaaagaagc cttggcaaaa   2820
 tgatggatga gagctttctg tcacaattct aaccttaaca gataatatgc ctcatgtgca   2880
 tttgggaaca ggatagcttg agccatattc ctagttgcct tgtcactgat tttatacatt   2940
 ttaaattgtg acttcctcta atcacgaact aaaatttaat attgtatata ataccggagt   3000
 attttatgcc tgcctcattt tattatatga ttagctcctg catttcttta gttctaagtt   3060
 tgtgttattt cagaataact aaagtacttc agaatgaaac tggatacagt atattcaatt   3120
 cataagtgta attgaccata cttgaatatg tttaagttta taagtaacat ct           3172



      <210> 2170
      <211> 2034
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(2034)
      <223> n = a,t,c or g


      <400> 2170
 atgaaactca tggaaacact taaccagtgc ataaacgctg gtcatgaaat gacgaaggct     60
 atcgccattg cacagtttaa tgatgacagc ccggaagcga ggaaaataac ccggcgctgg    120
 agaataggtg aagcagcgga tttagttggg gtttcttctc aggctatcag agatgccgag    180
 aaagcagggc gactaccgca cccggatatg gaaattcgag gacgggttga gcaacgtgtt    240
 ggttatacaa ttgaacaaat taatcatatg cgtgatgtgt ttggtacgcg attgcgacgt    300
 gctgaagacg tatttccacc ggtgatcggg gttgctgccc ataaagaaaa cactctcctg    360
 cctttctatc ttggggaaaa gggcgatgtc acttatgcca taaagccact tgctgggcgg    420
 ggcttgacat atttcttcct gtctggctct gcccggattg aaaatgagtt aatgggcaaa    480
 tttgttgaaa ggaaactggc cacccataca accttaagct tcgactggcc attggaaacg    540
 accccgcagc tactcccacc gcacatcctc tcgccggtct tcgcgtctgc gtctccctcc    600
 cgctgttggc gcgttgcttc gggcaagtac tgcaaggtgt tccggggctc tggattccaa    660
 gcccagnaga tcccccaacc tacgctgaga gaccctcact acgttgaaga caaaggccat    720
 aaataccttg tattcgaagc caacacggga acagaaaacg gataccaagg cgaagaatct    780
 ttatttaaca aagcgtacta cggcggcggc acgaacttct tccgtaaaga aagccagaag    840
 cttcagcaga gcgctaaaaa acgcgatgct gagttagcga acggcgccct cggtatcata    900
 gagttaaata atgattacac attgaaaaaa gtaatgaagc cgctgatcac ttcaaacacg    960
 gtaactgatg aaatcgagcg cgcgaatgtt ttcaaaatga acggcaaatg gtacttgttc   1020
 actgattcac gcggttcaaa aatgacgatc gatggtatta actcaaacga tatttacatg   1080
 cttggttatg tatcaaactc tttaaccggc ccttacaagc cgctgaacaa aacagggctt   1140
 gtgctgcaaa tgggtcttga tccaaacgat gtgacattca cttactctca cttcgcagtg   1200
 ccgcaagcca aaggcaacaa tgtgaaccgg tttacgcagt ttcggcttag tgaaacaaaa   1260
 gaaatcacca atccgtatgc catgcgttta tacgaatccc tgtgtcagta tcgtaagccg   1320
 gatggctcag gcatcgtctc tctgaaaatc gactggatca tagagcgtta ccagctgcct   1380
 caaagttacc agcgtatgcc tgacttccgc cgccgcttcc tgcagggcca gtttgaccat   1440
 gcggcgtccc ctgtggaacg gggtcacctc cggaagatcc ccttcagagg aggaacaaga   1500
 gagtctcggg aaagaggact ctcagaagca ggatacttgc cacgtgaggc aggccaagca   1560
 caaaaacgca gaccttggac taaagggccg ctggaaaaaa tagggcttga aaccttgcac   1620
 tgcgactcta gaagataccc ctgtcgttct aattgggttt ggatttgcac cgttaaggag   1680
 gggggaagag aaggaagagg cgggcgagga aggcgagtcc agctagcggc tgttgcgggg   1740
 accgtagccc cagctgcagc tccgaagaat cccccgccac ggtttcggtg gagcgtctgg   1800
 gcacgggatg gagtgaaaga gcgagtgcct ctccaagcgg gggtgggagg gggtcaggct   1860
 gtgcagagga gagagacagc gagaagaagc cgcggctggc tactgcgaat ttgggattcg   1920
 attgggaggg accgctcact cgggggaaat ggattcttta ccacggctga ccagcgtttt   1980
 gactttgctg ttctctggct tgtggcattt aggattaaca gcgacaaact gtga         2034



      <210> 2171
      <211> 1125
      <212> DNA
      <213> Homo sapiens


      <400> 2171
 ttaagccagc agggaagggc agatgtgggc tgctgtttca tgcatgcaca gaggcaggcc     60
 ctggctcttg cagcagcgga cttcacgaat gtggaatgtg gaggttacac agcgatgcct    120
 agactgtctg tccttagacc gaagggcagc agaaaggctc agggggcttg ctctatattc    180
 cttagacatc tccggagatt ttctcagcat cagaatcaga tcctcccatg gcctgcggct    240
 acttttaaga aagtttggca accttttgga tatgtcctct tctctttttt gactttccag    300
 gctgtaaacc ttcagaagct tccacatgtg gtgccagtgg gctccttgaa aaatgacttc    360
 cctgggaacc agaacatcca ggttggcctc aaacttgctg ccaaacagga actgtggcaa    420
 gccggagagg attctgatgc ttggaagtgg gcgaatgttt tgattttcaa gcaaagaaaa    480
 agctagcttc ctggtgaacc ctgtgggcat gaaccggtac agcgtggaca cctccgcctc    540
 cacctttaac cacaggggct ccttgcaccc ctcctcctcg ctgtactgca agaggcagaa    600
 ctctggagac agccaccttg ggggtggtcc tgctgccacc gctggtggtc cccgcactag    660
 ccccatgtct tctggtggcc cctcggcacc tgggatgagg cctccagcct ccagccccaa    720
 gagaaacacg acctctctat taaactctgg cttggaacct acattttctt ttcgtatcac    780
 ctttggattc atgtgacctt gtccgcagtg tgctgacttg cctctctcca cctgggaatt    840
 ccccaagttt cgatatgcac aggtatcagc tgccttgtgt acattaatac aggaagtgtt    900
 aggaggcgtt tgctcttctg gttctatttc attaagcaag ctgaagctgg atgtagaacc    960
 gtagaatcct agagttgggg aaaagaggtc ttgggggaca tctggacggc tcccctccag   1020
 agtagaacct tctcccccgt gggttccaca ttgctcagcg atgatgagag ctcctgttgg   1080
 tccacattct ggccagcatt tgtcagtatt acagatttcg cccat                   1125



      <210> 2172
      <211> 472
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(472)
      <223> n = a,t,c or g


      <400> 2172
 tggggangnn nnnaatcgag atccatagcc cgtgtggtgg aattctttct ctgctgtgga     60
 tgccactttt ggaatacgcc aggaacatgc taaggacctg gagctctcta ccctggaccc    120
 gttttcgggt ttgcttgctc tctctctctc tctttctctg ggctaatcgt ttagaggaca    180
 gtcgctcctg ccaacctaat cccatgagcc tgactacctt gccgggccac aggctcaaag    240
 aagcagtgtg gctgccagca ccctcacgca ccatgagtcc tcaccttgac cctaatcaac    300
 ttgggattct cctcagagta cttagaaagg aaaaggaaga cggtgactac cctgacatga    360
 tggccaccca cccgagctcc aggtatgaag cctgctcctc tggaattact ctagcggccc    420
 cgccgaccca cggcccacga cccaccgacc cacgaatcgg cccggccccc gn            472



      <210> 2173
      <211> 1476
      <212> DNA
      <213> Homo sapiens


      <400> 2173
 atggccatac tgcccaaggt aatttataga ttcaatgcca tccccatcaa gctaccagtg     60
 actttcttca cagaattggg aaaaactact ttaaggttca tatggaacca aaaaagagcc    120
 tgcattggca agtcagtcct aagccaaaag aacaaagctg gaggcatcac actacctgac    180
 ttcaaactat actacaaggc tacagtaacc aaaacagcat ggtactggta ccaaaacaga    240
 gatatagacc aatggaacag aacagagtcc tcagaaataa tgctgcatat ctacaaccat    300
 ctgatctttg acaaacctga caaaaacaag aaatggggaa aggattccct atttaataaa    360
 tggtgctggg aaaactggct agccatatgt agaaagctga aactggatcc cttccttaca    420
 tctcatacaa aaattaattc aagatggatt aaagacttaa atgttagacc taaaaccata    480
 aaaaccctag aagaaaacct aggcaatacc attcaggcca taggcatggg caaggacttc    540
 atgactaaaa caccaaaagc aatggcaaca aaagccaaaa ttgacaaatg ggatctaatt    600
 aaactaaaga gcttctgcac agcaaaagaa actaccatca gactgctagg caggcctcct    660
 gcgctcttca ctgcctctag cagcgtcttg aaacagctgg ctctggaagg catcctgatt    720
 ctggattcaa gagctttgct tggatttctg tatgaagctc ggcacagtca cagcaactct    780
 ccaaatcatg acgctcaaaa tgccacatct aaaaagaaca tccgggatgg ctatgataaa    840
 atctacagac aagaacaagt gttagcaagg atggaggaaa aaaccctcat cactgctggt    900
 gggaatgtga aatggtgcag ccactttaga aaacagattg gcggccagtg gctaacactg    960
 gagacgaaga ccaagacacc acagcctttc tccagtacct ctcaaatcag cacagacaag   1020
 gacaaaggcc tcaatccaca actgctgaag atggaccctg gccacatggg atggtgtcca   1080
 cctggtatgg gcatcccgtg gcagctctcc tctgatgacc gagtgtgggt cttggcagca   1140
 gccggctctg gaaggcatcc cggctctggg ttcaagagct tgctgggctt ctacatgaag   1200
 gcagttatgg acattgatga taatgatcat gaatatgagg tggcaattcc taaggtagtt   1260
 ctggtggacc tcagtgcatc agtggggaag agagagtttt tagggtggta caaagtatat   1320
 aaggaagaaa ctcctgagcc acttaaggat gagtctgaat gtgtggtgtt ggctagatgt   1380
 gggaagagct gcaaacacag tgaagtgaat gctgcaagga ctggtcatac tgaccaccca   1440
 gctgtgcaag gagaagagca accctggttg atgtga                             1476



      <210> 2174
      <211> 443
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(443)
      <223> n = a,t,c or g


      <400> 2174
 attgaatagc actacnccag ngcggnggaa ttctggagga cttcctgagg aatcaccatt     60
 atgcagtcag caggaagcac tccagctctg gggtggtggc cagcgagtct ctgaccaact    120
 acctggatgt ctccaacatt gtggaccccc accagactgt gggtctgagc acccaggaac    180
 ctggcgacat cttcacctac tccgagtttg atgggatcct ggggctggcc tatccctctc    240
 ttgcctctga gtagtcagtg ccagtgcttg acaacacgat gcagaggcac ctggtggccc    300
 aagacctgtt ctcagtctac atgagcaggc tccctgcact ggatacccat gactgcaaga    360
 atactggcag ttcactgtgg acaggtgggt gagcggccac actgtgtggg cctcagccag    420
 aggctgatcc agctgtgggg atg                                            443



      <210> 2175
      <211> 456
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(456)
      <223> n = a,t,c or g


      <400> 2175
 cgatgcggaa aaannaaact gagaccactg gagagcccgg nggaattctt tcaccatgtt     60
 ggccaagatg gtcttgacct cttgacctcg tgatccgccc acctcggcct cctgaagtgc    120
 tgggattaca ggcgtgagcc accgcgccca gcctcggatg gacattattg aactgacgca    180
 actgggtcat tgcccagctc tggaaccaca tgaatcagga ccaagccaag tcaggctcct    240
 gcttcctggg gactttggaa cctggcccac cacccaccaa ggtctcaccc ctcctgcccc    300
 atggccaacc ttatctgctc cacactgtct tcctttgatg ggggttctcc tggcactggg    360
 cctggaggct ggtgtccgct tggcctttct ggcagcccag cccgggcagt cttcaaagac    420
 agcagctgca gccttcaccc tctggccacg ggcatt                              456



      <210> 2176
      <211> 1005
      <212> DNA
      <213> Homo sapiens


      <400> 2176
 aaagacaggg tttccctctg tgtaatcaca aaggcacagt cacagctgat ttgcagcctt     60
 tacctcctgg gctcaagtga atttcccacc tcagcctcct gagtagctgg aactacaggt    120
 gtacaccacc acatccagct gatttttaat tttttgtaga gaggagatct cactatgttg    180
 cataggcttg tcttgaactg ctgtgctcaa gcgatcttcc tgctttgatc tcccaacgtg    240
 ttgggattac aggcatgagc accacacctg gccctatttg ccttttatga agtcttttaa    300
 taaagcaata aaaatattga aatgttttta gaagcttctg cacatcaata ggcatccttg    360
 aagactaatt gaggacccct catttttaag tgctgtgttg ttcattagga acggtccatt    420
 gtaattttaa agttaacaaa gattttgcca tttctgtaag tagttatttc ttctgaggcc    480
 taatatttat acattctacc ttatagctag aaggtagaat acggtgttct tcagatacta    540
 aggatccaat atttccctag aatcctggat ttggtcctca gatccccttc atcaatttag    600
 ttaatgattt ttccctacct aagggtacaa gaaaaagaat gtagaacaca aaaatctctg    660
 caaatttctg aagtctgcac ccactgtaat attaccattt ctgctagttt ctgcctgatc    720
 ctggacatct gcagcctctt aactgaatcc aagtcagtta attatcagat ccaatccaat    780
 catggatcca gtccagtttc tgttgtgact tccaaaccca gttcggatca gaagtttgct    840
 caaactcggt tccaaacaga aatctgtcga gcttcagaat ctcagcgaga acttaccacg    900
 atatcagttg cttccagaaa gcaatggaca tcgtgagtct gaggggtacc ttgcttggtc    960
 actccatgct cctgggcatg acatctgttg aaaaccttag acata                   1005



      <210> 2177
      <211> 838
      <212> DNA
      <213> Homo sapiens


      <400> 2177
 atggtcattg ttggcctggc agcgggggtc ttgttagtgg gtcctggtga tgggggtcta     60
 atcagtgagg gtgtggtcag ggaagacctg atgtgtgggg tctggtcagc aggaacctgg    120
 tcagtgggga ctgctgagcg ctgcttggag aagccaggtg cattgcacgt tatcgagggc    180
 cctctggaca gctgggatgg cccagtgatg cccaatggcc cggtcaaaaa tcataaagga    240
 gaacagcaag aggtccccag caaacatcca cagatggcct tggaaatctg cctgtgcttg    300
 gacttcctgt actacccatt cctgaggggc gatgcttctg cagggcctgt gacttggtgc    360
 acaacttcag acaccatcat cttgcagcag caccgcaccc tcactagcca gggtgttgat    420
 gacttcctca aggccaaggc cacattcaag gcttcggact ttattgatgc gcttgtgctg    480
 agcaaggatc ttaattcagg aggtagaatg gagcttgaga tcaagtgtct gatcaaggta    540
 cttgaacttg atctggaggg ctctggggag ccatggaagg tgctggataa aggagtgaca    600
 gtcagctatg ttttcgagat gactatagaa ggctgcctgg aaggagtgaa caagagccag    660
 gagaccaggg agggagcttg tggggcaggt ctggagatgg caaaggaggg atcctgcttg    720
 gatgaaaggt cttcagggac tgtctcaggt tacacacagg tgtcctcaga gctagtgtgt    780
 tcagggttct tgtctccagg atgaaaatgg gaaggagttg tcagacgagg acatataa      838



      <210> 2178
      <211> 549
      <212> DNA
      <213> Homo sapiens


      <400> 2178
 tctctaagtg aaaaatttgc atactagtgc ttgttataaa ggataatgca aaaataaact     60
 tgggaacttt gcattatgaa ttttattttt atatctacat aagcatgagg gaaagaactg    120
 tattttcaga taattaaatc cagaagagtt acaaattttc attcgtccca aagattttgt    180
 ctgggtattt cttccttagc tgtcgtcttg cagacaccat cgaagcatag atgatgcagc    240
 cccaggagat taaaacgatg gcaagcagca acactgaata aatccagtcc agcgtgcgac    300
 gacttactgg cttcatggta aggaggcggc agcagtccgc gggagctggc gggagctgcg    360
 ggccttacag taacctccca ggcggtggct gccaggcgcc agcagccatc ttttagccgg    420
 gcacgagcgc ccgcccactc gcttcgtgca gcgctgtcgc tggcctcttc cgcccggagt    480
 tggggggcgg tatcacgtga tcgggggcct tgcccgcccg ccataatgta tcagtcaagc    540
 aacaagtgt                                                            549



      <210> 2179
      <211> 384
      <212> DNA
      <213> Homo sapiens


      <400> 2179
 atgcttgtcc cagtcctgat cctaagcccc tgcctcgttg gcattgagcc ttgggaagtg     60
 tcaccccaca ccaactccac cagctcctac gaaagcaccc ccaaatcata ccctctaggc    120
 accgcagcaa aagcagcttc agggcaatcc cccagcacaa cctcacccct tcctgagact    180
 gctccctcca cccttcatga acgggggctg gaaaatgtgg tctgctctga taaggatttg    240
 cgtcaggcta ctggctactc agcagccgag aagagcaagc ctccaggcct ctgcacgcgt    300
 gccttctgcc cggaagccat ccctgatgcc caagactggg ttaagtgcca gcccctgggc    360
 tccctcagtg ccttgaattt ctga                                           384



      <210> 2180
      <211> 299
      <212> DNA
      <213> Homo sapiens


      <400> 2180
 aaaacctccc aagatacaaa gccttcagtg ttatggaaag atgtaaatag taatctatgg     60
 tgcaggccac atgatttgct aacatgggga agaggatatg cttgtgttca catcccctca    120
 ggtcctcttg ggattccagt gcaatgcatc aaaccatacc atggcatggc tgggacccaa    180
 tgcagtactg gaaatgaaga atgtgagcct gtaggacccg cagccccgga caatgcagct    240
 tcctcggaca acacaggtcc cggatgggga atgtgaaata tacaactggg ggatgctga     299



      <210> 2181
      <211> 3632
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(3632)
      <223> n = a,t,c or g


      <400> 2181
 atggcttttc tgaccaatgt acttgctttt catttcattt ttgtttttgt taaagagggt     60
 aagccagaga aattttcatt tggtcttctg gatcttcctt ttcgtgttgg agttccattt    120
 aatatccctc tggagtttca ggatgaattt ggtcatacca gtcaactagt aactgatatt    180
 cagccagttc ttgaagcaag tggtttatct ttacattatg aagaaataac caatggacca    240
 aattgtgtaa ttcgaggtgt tacagccaag ggccctgtaa actcttgtca aggcaaggtn    300
 gctccaaacc ttccagtcta tgttgtagat tgcagtagtt ctggaaccag tattttaaca    360
 ggatctgcaa ttcaagttca gaatattaaa aaagaccaga cgcttaaagc aagaattgaa    420
 atacctagtt gtaaagatgt ggcacctgtg gagaagacta ttaagttgct tcccagtagc    480
 catgttgcaa gactacaaat attcagtgta gaaggacaaa aggcaattca gatcaaacat    540
 caggatgagg ttaattggat agcgggtgat attatgcata atcttatttt tcaaatgtat    600
 gatgaaggag aaagagaaat caatataaca tcagctttag cagaaaaaat taaaggtctg    660
 cttcctgatg tgcaagtacc aacatctgta aaagatatgc gctattgcca ggtttcattc    720
 caagatgatc atgtgtcttt ggaaagtgcg tttacagtaa gcatgttgga actacttcaa    780
 ttaatggtgt cactaaagac ttctaacttg ttaaacaatt tcagaccact tcctgatgaa    840
 cctaaacatt taaaatgtga aatgaaagga ggaaaaacag tacagatggg ccaagagctt    900
 caaggagaag tagttataat aattacagat cagtacggaa atcagattca agcattttca    960
 ccaagttctt tatcttcttt gtcaattgct ggggttggac ttgatagctc aaatttgaaa   1020
 acaacctttc agtccattcc agtgattaat ggaagagatt tacagaaccc tattattgtt   1080
 caactttgtg atcagtggga taatccagca ccggtacaac atgttaaaat aagtcttaca   1140
 aaagctagca atttaaaggt taaagccatc tataacaaaa gtatcataga aggacctata   1200
 attaagttaa tgattcttcc agacccagaa aaacccgttc gtctcaatgt taaatatgac   1260
 aaagatgcat ccttcttagc agggggtctt ttcactggat atgttcgtcc agtaccagtg   1320
 ccacgcagtt taaatagtga tatttcctat tttggtgttg ggggcaagca agctgtcttc   1380
 tttgttggac aatcagccag aatgataagc aaacctgcag attcccaaga tgttcacgag   1440
 cttgtgcttt ctaaagaaga ttttgagaag aaggagaaaa ataaagaggc aatatatagt   1500
 ggatatatta gaaacagaaa gatttctatg tttgaaaaag ggaaggtacc taagattgtc   1560
 aacctaaggg aaatacaaga cgacatgcag acgttgtatg taaacacagc agctgatagt   1620
 tttgaattca aagctcatgt tgaaggagat ggtgtagtgg aagggattat cccttatcat   1680
 ccattcttat atgatagaga aacttaccct gatgatccat gctttccatc aaataatttt   1740
 ggaatcagct ttgtacattc acttgaagta attctanaat taaaagatga agatgatgaa   1800
 gatgattgtt tcatacttga gaaagcagct agagggaaaa ggcctatttt tgaatgtttt   1860
 tggaatggac gattaatacc atatacatca gttgaagana gagggcttgc accaattgaa   1920
 tgctacaata ggatatctgg tgcattattc actaatgaca aattccaggt cagcacaaat   1980
 aaattgacgt ttatggatct tgagctaaaa ttgaaagata agaacaccct ttttacaagg   2040
 attttaaatg gacaggaaca gcgaatgaaa attgacagag aatttgcttt gtggctgaag   2100
 gactgtcatg agaagtatga taaacaaata aaatttacac tttttaaggg agtaattaca   2160
 cgtcctgatc ttccttctaa aaagcaaggt ccctgggcaa catatgcagc aatagaatgg   2220
 gatggaaaga tatacaaagc aggacagctg gaacctcagg cactatatga tgaagtaaga   2280
 actgtgccaa ttgcaaagct ggataggaca gttgctgaga aagctgttaa aaaatatgta   2340
 gaagatgaaa tggcaagcct gtggatcctg ggctacaaac ctgtacagca catgactgta   2400
 ctgagtactg caggcaattg taacacaacg ttttggaaga aaataaacat taccgtgata   2460
 ctaagatgta gatctctgac caaggtccta ctggcaactg agcgaacatt tgaaacagct   2520
 ggtgtaggtg gtttaatttt aggtcaagtt gaagaagcaa gattaaaaga ggcccaattg   2580
 cgaaatgaac taaaaataca taatattgac attcctacaa cacaacaggt gccacacatt   2640
 gaagcacttc tgaaaagaaa gctatcagaa caagaagaac tgaagaaaaa acctagaaga   2700
 tcgtgtactc ttccaaacta tactaaaggc agtggagatg ttttgggaaa ggggcagagt   2760
 acaggactgg gacccgtgga agttacacag tccagcccat catctaggac atcagagtac   2820
 ttctggttaa caaagttctg ctggctggaa gactgggcat ctggtgaaag cctcaggctg   2880
 cttccactca tggtggaagg tgaaggggag ccagtgtatg cagagatcat atggcaaaag   2940
 agggatgaaa ctgttaaaga tggagtcacc ttatacctgc tacagtcggt caatcagtta   3000
 ctactgacag ctacgaaaga acgaattgac ttcttacctc actatgacac actggttaaa   3060
 agtggcatgt atgaatatta tgccagtgaa ggacaaaatc ctttgcnaat ttacacgcac   3120
 gtgggagacc gcgaagcgca ggcagcgtta aaactagggc gctggagtca cccccgtacc   3180
 ccgaatgccg tcggcgctcc agggccccca gagggtgcgg ggggcgggga cgctgtgacg   3240
 tcacagagcg cccttctgac gttctcacgg acccgctttg cctcgggggc ccacgctgga   3300
 gcccacccag tactactaag aaatgaggag gaaaaagggg cgccggctct cgtagcgcct   3360
 attttctcgg cagagggacc cacgtgctcg ctttggtgga ctctgcgccc ggcgagtacc   3420
 gccggcctga agcttcccgc acgccgcgtc cacgcgaccc agccagagag ggctcagtca   3480
 gccggcgcgg cacctacaag ctcagtcggg atcctggaga ggcgggaagg cagcggggcc   3540
 ctttccacag agagaacaca gctcttcggg agattccccc gctgccaccc gagccctgct   3600
 ctcccgcctc ggcctctgag gactacccgc ag                                 3632



      <210> 2182
      <211> 384
      <212> DNA
      <213> Homo sapiens


      <400> 2182
 atgctggcat cccccctgtg gctccaagcg ctgagcttgg cggcggggac ctggcggccc     60
 cggctcggct cgggacaggc aggaaactca gaaatgagag cagggttctt gcctggtgca    120
 ggcagccagg tccgagcaca gctgcaggac agattaccaa agaccactga aaccaaagga    180
 gccctctggc cacacactga gctatgcggg atgtggagca tcgccccagg tgcagagaac    240
 caggagctac agatagattc tccccttctg gggcagttga gcaatcaggt gtggagggaa    300
 gatggctatg gtaaggcctt taggttacgg actcttagct ccatggggat cactgaagag    360
 gccaatgaga atgttctgat ttga                                           384



      <210> 2183
      <211> 1221
      <212> DNA
      <213> Homo sapiens


      <400> 2183
 tcatccatgc tgtgaatgcg tcagtagtat attctttttc attgctgcgt tatattccat     60
 tataagaatg tcctcccatt tcttttccac ttgccagtcg atggtcaact taaggggtgt    120
 ctggtgtttg gtgatcatga atgaagctgc ctgtatgttc gcatctaagc cctgcgtctg    180
 tctcaagtca agggtcggtg cggcagggtg ggccactgag gcccagactc tgtcctcggg    240
 tgccctcgag gcgagaacaa tctttgcaaa atgaaactgt ctacagtatg tttcccccag    300
 ggccaccaga gggcgcgtgt gagcatctaa gtcagccgct tccctcctct gctcagaacc    360
 ctccgtggct cccacctcac tcgaccaaaa gccaaagtct gtatcataca aaggctctgc    420
 actgggccgg atgtggcggc gcacacctgt gcaaagagca ttctgggcag aggaaacagc    480
 acgtgcaaag gtcctggggt aggaatgtgc tgagatgtgg ctggggccat gtgagcgcac    540
 acgtatgtcg cacacgtatg tggctccgtg cacgggtgcg atcgctgcca gccatggaat    600
 tagttccctt ttccgaattc cagatgattt ttcatctctg taattaatgg gcaagtcagt    660
 tctgtccagc gcctctctgg ggtcggccca gcgtgtctct cctgcggctc ggcgaacccg    720
 ggccccccgc ccggcacatc tcccggagcc ggggcgcagc gccgatagct cccgcgccga    780
 cggctcgggc tccccgcagt ggccgcgggg agctcgggtt gggggcgggc ggctcggaac    840
 tggcggaagg gggcggcccg gctggaggca ggtgccgcgg cgtctctccc ccggattcgg    900
 ccggtagggg ggcaccgggc cgggccccgt gggcacctca gggaagcgcg gaccgagccg    960
 gcgccgggca ccagcaaatg acaaagccgc ctgttggcct cgcttcccgg ggcaacccgc   1020
 ttcttgaact ggatttaggg gtgagagagg agtcaagggt ttcagctcct ggggttctgg   1080
 ctggagggcc tgggaggatg gtggcaccgt gcactgatgt aggggcttat tttggtctgg   1140
 ttgggctgaa ggtgccttgg agttcccggt ggaagtatac atggctctgg ggggtccact   1200
 ctggagtctt agcattctag g                                             1221



      <210> 2184
      <211> 792
      <212> DNA
      <213> Homo sapiens


      <400> 2184
 tcaaagcttt gttgaccatc tccaggatac gatggccagc tgccttggag agccagtcac     60
 tccaggtgac acggtttggt actggacgtc cgcggtcccc tctcccacgc cgccccatac    120
 tgggccccgt atccagccgc caccgctgct gcagcaagaa ccgccccact gcctccgcgc    180
 agtgccattg tttaaaggga cctcagcctg acttccagga gctacgcaag acttggccaa    240
 gtcaatgcgc atggcaagga gagagccgct tctccccatc acagcgattc ccagggttgt    300
 cgtagaaacc actccctgag gcttcgcaaa gcaggagccc tccgtagcag ggcttcggtg    360
 tcggggctcc gaggctccgg cctgacttct ccacggggta cacaggaacg tctccggacg    420
 ccaggacctg aaatgggccg accaggatga ggaaaccaca ggcagaggcc ggggaagcag    480
 cgcggcatcc catcctcagg cctgcccgga cggtgttcgg gatcaagagg accacactcc    540
 agcccaggac aaaagcccca cggtagcaca ttgtccggca ggagaggagc agacccacgt    600
 ccaagaagaa gggtgtacct ttccacgcct cttctctgcg aaaagaagcc acaccatgac    660
 acaatcttga agaggaagcc gggaatggga gacggcaaca atccctgtcc ctggaacgct    720
 ggcctctatg gacaagccac ccgcttcgca cccctcccct tatgcccgag gcggaggcac    780
 ggcgccgtat cc                                                        792



      <210> 2185
      <211> 571
      <212> DNA
      <213> Homo sapiens


      <400> 2185
 tttttttttt ttttacaact gcacaaaggc tgtattgcag gggaggtggg agggggcagg     60
 cagaacgctc ctcctcctgg gtcttggggc cccggagcag agcccaggga tgggctgagt    120
 gaggggcttg gcactctgtg gaagctgcag atgagagacc agcaatgcat cagctgcacc    180
 tgcagtagag cgcggagata gcgttggacc agtctcctaa gatgccccgg cggtactcct    240
 ccaggcgcgg gtaggtgccg gcagagaact tgtgcgtctt gcccgccttg ccttgccggg    300
 accacacggt gagctcgcag cgcggggcca ccacaagtga ggaggcggtg ttggcccagt    360
 tggagggcag gtagggcagg tctgcgcccg actccagcga cagctcggcg cccccgcagc    420
 agttctcata gtaggggtcg ctcttgtcat agagcttggc gcaagtgcgc gtcccgtccg    480
 agtgcttgag gtcggcggag gcggggcagg cgccctgggc gcaaggcacg gaggcaaggg    540
 ccagggccag cagcagcggg cgcagcgggg a                                   571



      <210> 2186
      <211> 2856
      <212> DNA
      <213> Homo sapiens


      <400> 2186
 ctacttttgg taagcagaac tggcactgtg ggatgaaccg aatgccatgt taagatgccc     60
 gatgccaatg ctcatcacat cccagaaaag gtgttggttg atatagacag ctggacggtg    120
 gccatggaag ttggaatccg ctaaggagtg taacaactca gctgctgaat caactactcc    180
 ctggagaagc atgtgggagc gctggggagg gttctctttt ctttgtgaag ggcaggatgc    240
 cccggaatgg gttcgacccg agagagggga ctgtaccttg gaaagcatcg tggttctggt    300
 ggcatctggt gagctctggc tggcccttga aaatccaggg gagacagtgt aagtcttacg    360
 cagggccata cccatgtctg cagcagatct ccaagatgag cagactctcc ccccggcccc    420
 atctgtctcc tgttccccac tccgtggagg tggcgggcca cgtgctggtc cctgccacca    480
 gggcggcggt tccgtgcagc gcctcggctg gtgcttagca gtcgacgtat agaactggtg    540
 tgcaccaggg gaatccgact gtttaaacaa agcatcgcga aggccctcgg ggggtgttgc    600
 aaagtgattt ctacccagtg ctgttcgtgg ggaacctggt gctaaaccat tggtagacga    660
 cctgcttccg ggttggagtt tggccacaca tggccaacct ccacttgtgg ctgctcctgg    720
 gtcaggcctc tggggtcgac cagctgacgc ctgagggtgt gagacagctg gcggctcgcc    780
 atgtcccagg tcgaccagca ggccctctgg accgagcggt gtgcaggggt gcccgttggg    840
 atgagctgga tccggagcgt ccgcatctcg gtcggaacct ccagggtcaa ccagctgctg    900
 cccgcgagct ccggacttag ccggcggctc cctgtgtccc agattggcca gcaggcgacc    960
 agtggcggtc ccacggctac ctgccacctt ccagggagct ctgaggcgga tgcccccatc   1020
 acgtcccgct accctcccac agctggcctt tgccaggcaa cggcagggga accgctttga   1080
 cgctgctttc gaatcctccg gcgaagactt ccaccagatg ccccgggtgg gccggatggg   1140
 atgagactgg cccaccccag accgtgctgt tgttttgaag gcaaggcgag ggttaaagaa   1200
 agacagagag agacagttgg cggcttcaac agcaacactt ttattgccaa caaaaccctg   1260
 aggaggggtg aaccagctta gtgccagcgc caactgccgc tcacaggctg aggtaatcat   1320
 gggatgggag ggaggggtct gggtggtaga gcttgctgcc cagcaggaaa cggcaaggat   1380
 gtccctgcag tcaggctgtt ggacctttgc cccagggcct tgtgccatcc ctcctcgttc   1440
 cccctgatcc tgcccacgcc gttgtaaaca gctccttctt aatggcccgt cagctgatga   1500
 gagtttcctg ccagcacctg actgccacac tgctttgcca aagggaccag gctcctcggc   1560
 acaggagctg aggttctgct tcaatcctgg tgaatccatg ggatcgatga taaggtggga   1620
 atcagaggga agagcaaaat aaaggggagt gaaggtctga ttgtaacctg agacagtctc   1680
 tggagactgt tcatccaagc aggatccctc ccttgccatc tccagacctc ccccacaagc   1740
 tccctccctg gtctgctctt gttcactcat tccagtcagc cttctacagt catctctaac   1800
 acgtatctga ctggcccctc ctttatccag caccttccat ggctccccaa agcactccag   1860
 atcaagttca agttctttga tcggacagtt gatctcaagc tgcattctac ctcctgtggt   1920
 gcctacgtta ccatctgtgc ctaggatgtg caatgggccc ttgctcccac tgcagggttg   1980
 acgttccctc cagctggaga cctggtctcc tgacatcgcc tggcctgttt gtcctgctct   2040
 ttgtcccatc agaatctctg agcaagatct cccaggtcca tccagacacc tgctttgtcc   2100
 acttttgact gggccattga acaccactgg gccaccccaa ctgtccacag gctccttgat   2160
 aacatgcatt tcccctgaca tttcccagta gtgctcagca gcccccactg accaggtccc   2220
 gacaagggcc tcactgatga ggacacgccc accaggctct gctgactggg tcccatgtgc   2280
 ccagtcctcc actgaatagc accccttgac ctggtcacca gtgccccagc ccatgctgac   2340
 caggccagca ctaagtccca gatgaccagg tctccactga tcaagcccca cagcccaggt   2400
 ttgcactgac cagacaccaa acatctctgt cttcccttct gccacatgtt gcctgttgtc   2460
 cgtgactttg gtaagagctt ccttgtgtac gaggatgatg tccaggatgt tggtctggtg   2520
 tccctgagac agcactaaca ggtccatgcc tgggtccagg tccttcctgg actgattggc   2580
 aaagagctca ctgatgttct tgaaggcatc tctgcttaag tggatggccc ttccgtcttt   2640
 gatattagga acaatatcac agagggggtg tacaacttct gtgatattgt aatattcttt   2700
 cttcccatgg atattaggaa tgatatcccg ggggggcttg ttgtacaccc catccgtggg   2760
 ggagaggatg atattactct gcatatcata gagggtgcac acggctgtaa tgttgtccat   2820
 aataacatcc agaggggaag agaatattat tcccat                             2856



      <210> 2187
      <211> 1464
      <212> DNA
      <213> Homo sapiens


      <400> 2187
 atgagggagc tttattcaat ctggctgaag ggctattgga ctgaagggga ctgggctcaa     60
 tcacccccaa ggagcccacg ggaagctctc gaaggaatcc gggttcatct caggtgcttc    120
 aaagcctatg gaattatagt tctttgccag tgtccatgga acacccccct cctgccagtc    180
 cctaagccag ggaccaagca ctacgaacca gtacaggact tgcgcttggt caaccaagct    240
 acagtgactc tgcacccaac agttcctaac ccttacacgt tgttagggct gctgccggct    300
 gaggacatct ggtttaccca tctggactta aaagatgcca tctgtagcat cagaatagct    360
 cctgagagcc agaagctgtt tgcgtttcag tgggaagatc tacagtcagg tgtcactact    420
 cagtacactt ggaactggct tccccaaggt tgggtgctca aaagggttga tgccctgttt    480
 cagcacctgg aggactgtgg gtataaggtg cccaagaaga aatctcagat ctgcagacag    540
 caggtacgct acctgggatt cactatttgg aaaggggagc acagcctgtg gtcagaaaga    600
 aagcaggtca tctgcagcct accggaacct aaaaccagaa ggcaagtaag ggaattcctg    660
 ggagctgtgg ggttttgcac attatggatt ccaaactttg cagtgctagc caaacatttg    720
 tacggcatta caaagggggg caactgggag ccttttgaat gggggcctct acaacagcaa    780
 gcctttttat cagagagccc agtcgagcat aactgtgtag aggtgttgga ctcagtttat    840
 tctagcagac ctgaccttag ggaccagcca tgggcatcag tagacttgga gttatatttg    900
 gacgggagta gcttcatcaa cccacaagga gaaagatgtg cagaatatgc ggtggtaact    960
 ttggatgctg tcattgaaac caaaccattg ccacagggca cttcagccca gaaggctgag   1020
 ctcattgctt taactcgagc tctagaactc agtgaaggtg attgcatttg gatcaaagac   1080
 tgcaacatag cccctttgag gccacggtgg aaaggacctc agaccgtcat cctgaccacc   1140
 cccacggctg taaagagaag catagccata gggaattggc aagatgatga atggctccct   1200
 gagagaatca cacaatatta tgggcctgct acttgggcac aatacggctc gtggggatac   1260
 tacaacccca tttacatgct caaccaaatg atatggttac aagctgtctt agaaataacc   1320
 actaataaaa ctggcagagc cttgactatt ctggcctggc aagaaactca gatgagaaat   1380
 cctacctatc aagatagatt ggctctcgac tacttactag cagctgaagg aggggtctgt   1440
 gggaaattta accttactaa ttga                                          1464



      <210> 2188
      <211> 511
      <212> DNA
      <213> Homo sapiens


      <400> 2188
 gcctttcttt tatacatctt cctcaaccta cagctcatga tcttgcaggt ccttcacctt     60
 tactggggtt attacatctt gaagatgctc aacagatgta tattcatgaa gagcatccag    120
 gatgtgagga gtgatgacga ggattatgaa gaggaagagg aagaggaaga agaagaggct    180
 accaaaggca aagagatgga ttgtttaaag aacggcctcg gggctgagag gcacctcatt    240
 cccaatggcc agcatggcca ttagctggaa gcctacagga ctcccatggc acagcatgct    300
 gcaagtactg ttggcagcct ggcttccagg ccccacaccg accccacatt ctgcccttcc    360
 ctctttctca ccaccgcctt ccctcccacc taagatgtgt ttaccaaaat gttgttaact    420
 tgtgttaaaa tgttaaatat aagcatgccc atggattttt actgcagtta ggactcagac    480
 tggtcaaaga tttcaaagat ttctccacaa a                                   511



      <210> 2189
      <211> 523
      <212> DNA
      <213> Homo sapiens


      <400> 2189
 ggcacgaggc gcggccgttc cgaggggcgg tccctgggct cccgctcgcc gccgctgccg     60
 ctcctcgttc tgctcctcac tccccagcgg ctggaggccg gtaccggcgg gcaggaggcg    120
 cccgaggatg tgctgctggc cgctgctcct gctgtggggg ctgcttcccg ggacggcggc    180
 ggggggctcg ggccgaacct atccgcaccg gaccctcctg gactcggagg gcaagtactg    240
 gctgggctgg agccagcggg gcagccagat cgccttccgc ctccaggtgc gcactgcagg    300
 ctacgtgggc ttcggcttct cgcccaccgg ggccatggcg tccgccgaca tcgtcgtggg    360
 cggggtggcc cacgggcggc cctacctcca ggattatttt acaaatgcaa atagagaagt    420
 tgaaaaaaga tgctcagcaa gattaccatc tagaataagc catggaaaat aacacacacc    480
 caataattga atttaccaga gagctgcata catgtgacat aaa                      523



      <210> 2190
      <211> 1346
      <212> DNA
      <213> Homo sapiens


      <400> 2190
 ggtggtggaa ttcgcggatg tggagaagaa aggtgctggc aggacagagt tccgctaccc     60
 ttcctatgtg cagcacatca tgggggacat attctcccag ggatttgggc ctttccgctg    120
 ggtgtgcaca tcgggggacc cccaggacct ggcggtcaca gacgaactgg ccacatctgt    180
 gctggaggaa gccattgctg atggagtgaa ggtgtctgtg aagctgcagt acatggacaa    240
 catccgctgg atccgggagg ccgccaggca ccggctggtg gtgggctccc aggcaaggat    300
 cctgtactca gaccagaagg gccgcgtggc catcgctgtg gccattaacc aggccatcgc    360
 ctgcaggagg atcaaggcgc cggtggtcct gagccgagat caccatgacg tgagcggcac    420
 cgacagcccc tttagggaga cctccaacat ttacgacggc tctgccttct gtgcagacat    480
 ggctgtgcag aacttcgtgg gagatgcctg tcgcggagcc acctgggtcg cccttcacaa    540
 cggagggggc gtgggctggg gtgaggtgat caacggggga ttcggcctcg tgctggacgg    600
 taccccggag gccgagggga gagccaggct gatgctcagc tgggatgtct ccaatggtgt    660
 ggcccggcgc tgctggtcag ggaaccagaa ggcctatgag atcatctgcc agaccatgca    720
 ggagaacagc accttggtgg tgacactgcc tcacaaggtg gaggacgagc gggtgctcca    780
 gcaggccctg cagctctgag ggagccagga gtcgcggccc ctgcctccct tcctccctgg    840
 cgatcctcac ctgcccagcc atggcacaca cccttcctgc acacccgcac tacctgcact    900
 tctcgcacat cctcacgtgg cccttatggt gccctgtgca gggtgccacc acagcctcat    960
 tttacagaca gccccctgag gcccagagac atgcagctct ctgtccacaa ccatgccact   1020
 tgcatgggag ccctgaaggc tgtcaaagtc catttagggc caagtcccaa gcctgcccgg   1080
 gggccctgcg gtgaacactg gtcaagctct ctccggctgg gatgatcaca ccctctgctt   1140
 cctggccacc tgccagcctc catgcaactc tgtctgtctg ctgcccatct gctgtctgtg   1200
 caagcaactt ctggaccctg gcaccctggg ctgctggcct ggaggagttc gggaaggagg   1260
 atagaccagg aaataaaggg tcaacagagc tgtgtgctgc actgtgggct ggtgggacgg   1320
 ggcaggccgg gtcttgccta aggata                                        1346



      <210> 2191
      <211> 3018
      <212> DNA
      <213> Homo sapiens


      <400> 2191
 cagatctcca gtggcagaga gttgagagtg atccaggaaa gtgaagcagg agatgcggga     60
 ctgccccggg tggaagtgat cctcgactgc tctgacaggc agaagacaga agggtgcagg    120
 cttcaggcag gaaaggagtg tgtggattct ccagtggaag gagggcagtc agaagcacct    180
 ccttctctgg tatcctttgc cgtctcatca gaaggcacag agcagggaga agatccacgc    240
 tcggaaaaag atcacagcag acctcacaag caccgagcgc ggcatgcacg gctcaggagg    300
 agtgaaagcc tgtcagaaaa acaagtgaag gaagcaaaat ctaaatgcaa aagcattgcc    360
 cttcttctaa cggatgctcc caaccccaac tccaaggggg tgttgatgtt taagaagcga    420
 cgtcggaggg ccaggaaata caccctagtt agctacggta ctggcgagct tgagcgagag    480
 gcggacgagg aggaagaagg tgacaaggag gatacatgtg aagtagcatt tcttggtgca    540
 agcgaatcag aggtggatga agagttattg tctgacgttg acgacaacac acaagttgtg    600
 aactttgact gggattctgg actggtggac attgaaaaga aactgaacag aggggacaag    660
 atggagatgt taccagacac cacaggcaag ggagccctca tgtttgccaa gaggagggag    720
 agaatggatc agatcacagc ccaaaaagaa gaggacaagg taggtggaac gccaagcaga    780
 gaacaagatg ctgcccagac cgatggcctg agaaccacga cttcttacca aagaaaggag    840
 gaagagtcgg taagaacgca gagctctgtg agcaaaagct acatcgaggt gagtcatggt    900
 cttggccatg ttccccaaca gaatggcttc agtggggcat ctgagacagc aaacatccag    960
 aggatggtcc ccatgaatag aacggccaaa cccttcccag ggtctgtgaa tcagccagct   1020
 acccccttct cgccaacccg aaacatgacg agtcccattg ctgactttcc tgcacctcca   1080
 ccttactctg cagtcactcc tccccctgac gccttctcca gaggggtttc aagtccgatt   1140
 gctggcccag cacagccccc tccatggccc cagcctgccc cgtggtccca gccagccttt   1200
 tacgattcgt ctgagcgaat agcttcccga gatgagagga tctcagtgcc agcaaaaaga   1260
 acaggaatat tgcaggaggc caaaaggaga agcacgacaa aacccatgtt tacttttaaa   1320
 gagcccaaag taagcccaaa tcctgaactc ttgtcactcc ttcaaaattc agaaggcaaa   1380
 cggggcactg gagctggagg tgattccgga ccggaagaag actacctcag cttgggggca   1440
 gaggcttgta atttcatgca aagctcctct gccaaacaaa agaccccctc ctcctgttgc   1500
 tccaaaacct gcaagtcaag tcctcatcct cccaaccagt aactccagtt tccccagtct   1560
 ggtctccagg agtggctccc acccaacctc ctgccttccc cacatccaac ccatcaaagg   1620
 gcaccgttgt ctcctccatc aaaatagccc agccttctta ccctcctgcc cggcctgcaa   1680
 gtactttgaa cgtggctggt cccttcaaag gaccacaagc agcagtagcc agtcagaatt   1740
 acacacccaa accaacagtt tccacaccaa cagtcaatgc tgttcagcct ggtgcagtgg   1800
 gaccatccaa tgagcttcca ggaatgagtg ggagaggagc tcagctcttt gctaaaaggc   1860
 agtcgagaat ggagaagtat gtggtcgatt cagacacggt gcaggcccac gctgctcgag   1920
 ctcagtctcc cactccatct ctcccggcca gttggaagta ctcctccaat gtccgagcac   1980
 ctcctcctgt ggcctataat cctatccact cgccgtctta cccactggct gctctcaagt   2040
 ctcagccatc agctgcacag ccctccaaaa tgggcaagaa aaagggaaag aaacccctca   2100
 atgcattaga tgtcatgaag caccaaccgt atcagctcaa tgcatccttg tttactttcc   2160
 aacctccaga tgcaaaggat ggcctccccc agaagtcatc agtcaaggtc aattcagccc   2220
 tggccatgaa gcaagctctt cctccccggc cagtgaatgc tgcctcacct acgaatgtgc   2280
 aggcttcgtc agtgtactcg gtaccagcct atacctctcc tccttccttc tttgcagagg   2340
 cctcctcacc agtcagtgca tccccagtgc ctgtgggcat tcccacctcg ccaaagcaag   2400
 aatcagcctc atcatcttat tttgtggcac caaggccaaa gttctcagcc aagaaaagtg   2460
 gtgtcacaat tcaggtgtgg aaaccatctg ttgtggaaga gtaatcttgt agctgaagct   2520
 gagtgtccac tttgcttgaa atgaattgtt tgcagtgttt cttgagtccc tgagaatgcc   2580
 tagcaaagtc ctcaacttac ttaatttcag atatgtcacc tcctaatctg ggtccaagga   2640
 gtataatatt tttaatgagt caaaaatcca actcagattg acctaaaata tatttatctt   2700
 ctttgcacac ttaaaaaatc caggagcacc ccaaaataga catgtaccgt tatattaagt   2760
 aagcaggaga cttaggattt gtgctgtagc cacaagaaag acagtgatca gtgatatcaa   2820
 acatcaggaa tcagccttta tgtaacataa cagctgtcct tctatggtga aaggttcaaa   2880
 tgtagtgaag gtataaccta tattgactga gatttccctt ttaggtagtg ccttatctct   2940
 attactagtg ttaaaggaat aaggaatcta tgaaggacag ggagcagctc tggtctgtca   3000
 atctcagcca cctgtttg                                                 3018



      <210> 2192
      <211> 937
      <212> DNA
      <213> Homo sapiens


      <400> 2192
 tgtttttata aaaaagtagg gtttattgac tcttatgcat tgttaaatta gagggtaaaa     60
 agacagagct ggtagtcttt ccctgaaggc tgtaaggtta tttttggggt ttggtgactt    120
 ctcaggttgg cagccgtctt gttgatgtcc cctatgtcaa tccagagggc aggagcgggc    180
 agctctctac cttggcaact ggttcctctc tctccagctt catcttttcc attgtttttt    240
 gtttgtttgc ttgtttttgt ttttcatttt taccttttac agattgattt aaacattttt    300
 taaaccacat gcttcttttt ctgggctcca gccagatctc tgggggagga gttgttggca    360
 gtggtgatgg aattgggaag ggtctgtgag aaaatctgag gagcttcctg cctcccccag    420
 atctccctca caagactgtc tctctcaggg ttgcttgtga gaatcattta ggaactgctg    480
 cagtgttttg atgttttctg aacccctccc cagaaagccc aggagtttgt aattgaaaca    540
 agaagtcaag ggaaagaccc agaatcatct tttccccaaa gtcattagag gaggccagta    600
 aatgtgttta gggggcacaa gttcccaaac gccaccccac cattccttcc taggaagttc    660
 tcaaaggtac agcaccaaga acctgtccct cctctttcat ctcctcctcc ctcctgttct    720
 cctcctgggg ctggagagcc agtgctctga aagaggagag gggagaggag gagctaagat    780
 agctgatgcc agcgttctgc tgtccggggg tgacagtgat tgccgaaccc ttaaagtgtt    840
 gcctgaaggt tggggtccag gatggtttct cgatctggag actcaatgta gttggcagct    900
 tcttgaagtt tcagcagcat ggccatcaga ggatctg                             937



      <210> 2193
      <211> 452
      <212> DNA
      <213> Homo sapiens


      <400> 2193
 agaaagcctg ggggtgaaca cgccctgagg agtcagggaa gccagagcca gcggctgaag     60
 ggcccttgcg tgcggctgca gcacaactgc aggttctcag agaaaaatct ccagctcaga    120
 cccggttctg cacaaagctc agaatggagc ggccagcagg gcatgtggct agaggaagga    180
 catggccacc cacccctccc tcctggtgtg ccaggtgggc ttgctagggg cacaggtgcc    240
 cagtgtcagg gcagggatgc cacagagccg caggcagact gaaggggccc agggcatggt    300
 caggaacgaa gaaggaggga gcctgaggct ctcccaccac caggcctgca aagccactca    360
 cactcagcag tggacacttg aggtcacggc ccaggtgggc tgagggaccc caataccacc    420
 tgccttgaat ctcagcctgc agaagtcgtt cc                                  452



      <210> 2194
      <211> 591
      <212> DNA
      <213> Homo sapiens


      <400> 2194
 atgactatcc acatcctcat cctgctgttg ctcctcgcct tctccgccca aggggacctg     60
 gacactgcag ccaggcgagg ccagcaccag gtcccccagc accgcgggca cgtctgctac    120
 ctgggcgtat gccggaccca ccgcctggcg gagatcatat actggattcg ctgtctccac    180
 caaggagccc tcggggaagg ccagccacga gccccaggac ccctacagct atgggcgccg    240
 ccggtggcgc gaggcggaag cccggctcgg ttcccaggat tccggcctgc agcgaggggg    300
 ctagcgcagt gcccagctcg ctgggtgacc tcgggcacgg ctcgtcccct cctcggcttc    360
 agtttgccta tctggctcca gcgtgacatg gctgaagcgc accaggccgt gggcttccga    420
 ccctcgctga cctcggacgg ggctgaagtg gaactcagtg cccctgtgct gcaggagatc    480
 tacctctctg gcctgcgctc ctggaaaagg catctctcac gtttctgggt gaggagcggt    540
 gctggtcggt ttccttccgg ggatccaggt ttctgcttcc gggatgtctg a             591



      <210> 2195
      <211> 796
      <212> DNA
      <213> Homo sapiens


      <400> 2195
 tttcaggagg ctgcagttca gctttattct catgcccctc atgtccagtt aaggctcaag     60
 atcagcccag gccacagtcc cccagcactg ggactcagct tcccacctgg acagggcagg    120
 gggttctctt gccaactcct gccagcctcc ttcagctggg ggatccccca gagaccgctg    180
 cctcagcggg agccacctgg aagaaccaga actccagcct ggagctgctc gtgggggcca    240
 gccatccccc ctgtccacac actcgtccca gctccatctc cgggccccgg cgctgaccgt    300
 ggaggatctc agggcccagg cctccttgtc caaggactcc ccttggggtc cctggctccc    360
 tgagctcttg ggctgcctgg ggcctccgct gacactccag tgccgagaag gctgcactcc    420
 caagcctgct gttcccacgg tgtcactggc tgagggatgg ggtgagggga cgtttctccg    480
 gttcctgtac ctcagggccc tctcggttgg catctgtttc gtgttcctgc agggtctcag    540
 cggagttctc ccatcccaca ccaggtcctg ggaggcacaa ggcaaccact gggcccaggg    600
 ccagtgcgga agtggacaga gcttgcagga gacacagggg acaagaagga agcctcctcc    660
 cccaaggagc tggtgggtcc acaaagagtt ggggggctgg ctggtacagt gacccttgtc    720
 cctcaccttt gctgtgggag acgggcgccc ccagggggcc tggatggcgc tgtcgaaatc    780
 gttgcctagg ggtgtc                                                    796



      <210> 2196
      <211> 3395
      <212> DNA
      <213> Homo sapiens


      <400> 2196
 gtttttaatt aatagacttt atgttttttg agcaacttta ggtttctagg aaaattgagc     60
 agaaagtaca gcaagttccc ttgtgccccc atggcctcag tttcccatga ccttagttcc    120
 gctgccctca gtttcccctg ctgctcctgt cttgccttgg cgtgtctgtc cctactgcag    180
 ccaggctgat ctgtcccagc gcacctcact cttgcctcca gccatgggca cggcctcatc    240
 gcgtctgcgt tccccgctgg aggccttgtg gaggccctca cccatggcag cttttgcctt    300
 ccctctagag tttaaagaaa cccattatcc ccaaagagtt tgggggcaaa gtccccaccg    360
 tcatccgcca gcgctatctc aacctgttca tcgaggagtg tctcaagttc tgtacctcca    420
 accaggaggc catagagaag gtgaggtcct ggagttccta tctggccggt cgggtgggga    480
 ctaggggtcc agggtggtcc ccagacatcc cccggcctct cagccgcagc tgtgacccgg    540
 agctgcctgg gagagatgca agtccccgac cccatggcga ccccaccgct ggggctcccc    600
 ggcaccaggc aggcatggcc tcagctgggc accgcctgtc ccccaggcac tgaacgagga    660
 gaaggtggcc tatgaccgca gccccagcaa gaacatctac ctgaatgtgg ccgtgaacac    720
 cctcaagaag ctcaggggcc tggcccccag cgctgtgccc ggcctcagca gtgagtcctg    780
 gcgggtgggc gggggaggct cagggttgct cttggggtgg cagctgggct gggaccctcg    840
 ctgggacctt cacagccctg agctcagcca cagtctcaga caaaaggaaa gcgcggtgct    900
 gtgggggggc tgcctgctgc ctggttccca ggcttctgtg taggacggac ctggccctgg    960
 tgtcctcgct gtcagccgcc ttcctccgct gagtggggtc tccaagccga gccgaggggc   1020
 cgcctgctaa tggagctgcg gcagcttctt caaagcagga ggcccagggc tgggcgagct   1080
 ccatgcatta agctctgggg aggaagaaag cggagacctg ggcgtttcat tgcagcctct   1140
 ccaggctgca ttaagctatc accggcccct gcccccgtcc ccgcctgcat tagcactcgg   1200
 aggggccctg ggttggcgtc gcaggctggg tggcccatga aggctcaaag ccctcgaaag   1260
 ccattagatc ccccgtgctg ttctccccgc ccttccccct tcgcttgagg ggaggggacg   1320
 aagactttgg gtgtggggcc tccgtgcagc tctggggcct gcagagctgg cggctgccct   1380
 gcgtccctgg ctcaccgcat gtctgcctct cctgttcggg tcaggctgga acccggggtc   1440
 agtggggtgc tgtcccagaa agggggagtt gaggcagagg tctgaggagg gcagggtggg   1500
 tgggagagca ggcggggcag gggtctgagc cagctacttc acaccctcct cccctccctc   1560
 ccttccttcc agaaaccagt ggccgcaggg ttgtgtccca cgaggtggtg ttggggggca   1620
 ggttggccgc caagaccagc ttctcgctca gccgtccaag cagcccccgg gtggaggacc   1680
 tgaaaggtaa ggccctgccc ctgctctgcc acacggtgct tcgtgggcct ctgccggccc   1740
 agcccctgct gtgccacacg gtgcttcgtg ggcccctgcc ggcccagccg cctttcccgg   1800
 tggtgtctac cgccccgtgg gccatcccag gcaggggctg accactgtgc ctgtccacag   1860
 gggctgccct gtacagccgc ctcagggagt acctgctcac ccaggaccag ctcaaggaga   1920
 acggctaccc cttcccgcac ccagagcggc ccgggggcgc aatcatcttc acagctgagg   1980
 agaagaggcc caaggactgt gagtcgctgg cctgcgacgg cctaggtggg caggtgcggg   2040
 atgtgggcaa ggccgggcat gcgggcccca gcgtgagcct cagcttccac ctgggtcccc   2100
 acccacagct tcctgcagga cctgctgccg ctgtggcacc gagtacctcg tgtcctcttc   2160
 aggccgctgc atccgggacg aggagtgtta ttaccactgg ggacggctgc gccggaaccg   2220
 gggtaaggcc ttacccgggt ccttcccctt cccacccatg gcccccggaa cctgggccct   2280
 cccttgaggc ccccagaact ggggtaaggc tttacccagg ccctccatcc cactcagggt   2340
 ccctgggctg caccgtcttt ggcagagccg gggctagccc ttggcctcat tttctctcca   2400
 cctgttcttt atgcaaaagt aagacaagag ctttcccatg acaaggttca aatgccacca   2460
 cctgaaaggc cctgtgtccc tgccttcctg tgcccttggt ccatggaaat gtggaggttg   2520
 ctggccccag gagcggaggg gcttgtccca cccttggcct ggtggttcta ttcaatcccc   2580
 caggcaacca cgcagccacg ctcagggcac atggccagcc ttgcacagcc ctgtggcggc   2640
 ccctaaagcc atcgcctcag ggatacctgg agggtgctgc ccggggcagc gctgccaaga   2700
 ggcctctgca gagggcactg gtctccctgg atccaggcct gggcgtcctg gctgccacac   2760
 gactgccggg gcctgtggcc ggaggctggg agacccagta catgtgctgc tcggctgccg   2820
 ccggctctgt cggctgccaa gtcgcaaagc aacacgtgca ggatggccgg aaggagcgcc   2880
 ttgagggctt cgtgaagacc tttgagaaag agctctcagg agacacccac ccggggatct   2940
 acgccctgga ctgcgagatg tcctacacca catatggcct ggagctgacg cgcgtcacgg   3000
 tggtcgacac ggacgtgcac gtggtttatg acaccttcgt gaagcctgac aacgagatcg   3060
 tggactacaa caccaggttt tcgggggtga cggaggctga ccttgccgac acaagtgtca   3120
 cgctgcgtga cgtccaggcc gttctgctga gcatgttcag cgctgacacc atcctcatcg   3180
 gacacagcct ggagagcgac ctcctggccc tgaaggtcat ccacagcacc gtggtggaca   3240
 cgtctgtgct cttcccccac cgcctgggcc tcccctacaa gcggtccctg cggaacctca   3300
 tggccgacta cctcagacag atcatccagg acaatgtgga tgggcacagc tccagcgagg   3360
 acgccggcgc ctgcatgcac ctggtgatct ggaag                              3395



      <210> 2197
      <211> 556
      <212> DNA
      <213> Homo sapiens


      <400> 2197
 ctgcatcacc cggactagcc aggtcctggt catcctgatg gatgtgttca cggatgtgga     60
 gatcttctgt gacattctag aggcagccaa caagcgtggg gtgttcgttt gtgtgctcct    120
 ggaccaggga ggtgtgaagc tcttccagga gatgtgtgac aaagtccaga tctctgacag    180
 tcacctcaag aacatttcca tccggagtgt ggaaggagag atatactgtg ccaagtcagg    240
 caggaaattc gctggccaaa tccgggagaa gttcatcatc tcggactgga gatttgtcct    300
 gtctggatct tacagcttca cctggctctg cggacacgtg caccggaaca tcctctccaa    360
 gttcacaggc caggcggtgg agctgtttga cgaggagttc cgccacctct acgcctcctc    420
 caagcctgtg atgggcctga agtccccgcg gctggtcgcc cccgtcccgc ccggagcagc    480
 cccggccaat ggccgcctta gcagcagcag tggctccgcc agtgaccgaa cgtcctccaa    540
 ccccttcagc ggccgc                                                    556



      <210> 2198
      <211> 1068
      <212> DNA
      <213> Homo sapiens


      <400> 2198
 ttagcattta aatgtgtgaa tcctgccctg tgagtactgt gtagatctag gcttaaacgt     60
 gtgaatcctg ccctgtaagt actgtgtaga tctaggctta aacgtgtgaa tcctgccctg    120
 tgagtactgt gtagatctag gcttaaacgt gtgaatcctg ccctgtgagt actgtgtaga    180
 tctgggctta aacgtgtgaa tcctgccctg tgagtactgt gtagatctgg gcttaaacgt    240
 gtgaatcctg ccctgtgagt actgtgtaga tctaggctta aacgtgtgaa tcctgccctg    300
 tgagtactgt gtagatctag gcttaaacgt gtgaatcctg ccctgtgagt actgtgtaga    360
 tctaggctta aacgtgtgaa tcctgccctg tgagtactgt gtagatctag gcttaaacgt    420
 gtgaatcctg ccctgtgagt actgtgtaga tctaggctta aacgtgtgaa tcctgccctg    480
 tgagtactgt gtagatctag gcttaaacgt gtgaatcctg ccctgtgagt actgtgtaga    540
 tctgggctta aatatactca agctgcttac agtcacaagt atgaatgtca tagcttcatg    600
 gagcaggagg gagcacatta ccaccacagt gtctgtcaaa agagatgctc ccagaagcca    660
 gaggccctct tctggaggtg ctagtcctct gtttcccacc ttggagtatg acggcagagg    720
 catctcttgt tttctcacta ctgtcaaaga tagtataccg aaagaaatca tgtttgaaac    780
 agtcgggttg tcttcttcct gaagagcaat ggagccgctt ttacttggaa gaggactaat    840
 cgtatatcta atgttcctcc tgttaaaatt ctcaaaagca attgaaatac catcttcagg    900
 taaagttaaa acattcagtg caattttact gtccatggat tccccgttcc aggctggcgg    960
 cattttcgga accccccccg ggctgggatc tagaatcctc tccccctccc cgatggtttc   1020
 actcggttca tgttgcacac acaggtcgcc aatctgcttt tctcccat                1068



      <210> 2199
      <211> 706
      <212> DNA
      <213> Homo sapiens


      <400> 2199
 atggctgagc gggctgctgg gggccagctg ccaagccagg gtccagtcca gctcccatcc     60
 acacggaagg aaaaggatga acaaactgaa aatcaacaac tcttcttcat ccgtcagaga    120
 actgagtcac caggcaaagc acggccccca aatctggaga cacagacaag cgggttccaa    180
 gaacctcagc tgacaggagc agaacctctg cggggccaat gccacggact tgagctgccc    240
 ctcatgaatt tctggagatg ccacctggac aaaactaact tacgattaaa agaagagttg    300
 aaggcagaga agaaatctgg attttgggac aatttggttt taaaacagaa tatacagtct    360
 aaaaaaccag atgaaattga aggttgggag cctccaaaac ttgctcttga agacatatcg    420
 gctgaccctg aggacaccgt gggtggccac ccatcctggt caggctggga ggatgacgcc    480
 aagggctcga ccaagtacac cagcctggcc agctctgcca acagctccag gtggagcctg    540
 cgcgcggcag ggaaggctgg tgagcatccg acggcagagt aaaggccacc tgacagatag    600
 cccggatgag gccggagtga ggggggctgc gtggcaagtg tgcccccgac atggtggcct    660
 tttatgagta taccatgtag ttgttgagtc ttttccgcgt tagaaa                   706



      <210> 2200
      <211> 526
      <212> DNA
      <213> Homo sapiens


      <400> 2200
 tttcgtctgg gaagaaaacc gaggtgaggc ggtgtcatgt gacctgtctg gtcccgtgga     60
 gagccgggca gcgtgggggc ggaggctggc cctcctgatc tgcacccagg cggcttctac    120
 accaccctgc agcaggcctg gccaccggcc tcagcgcttc tgggagaagg tcagccaggt    180
 ggaagatgga gagggcttct ggactgagcc ctggaggggg gctaggggcc accagcaggc    240
 agatgagccc tgggacccag ctggccaacc cacctgacca cggtgacaag gactgcttgg    300
 gaaggataag cccaggttcg ggaaagcaaa ttcaggctgc aggacagctg cccgggcccc    360
 ccacaagcct ggcaccagcc cagggaagac tgaggagcct cactccatgg ggactgcaaa    420
 cacctgaaca cagcgaacct gaaggtatag ggcatcttca ggctgctact gaggcggtcc    480
 tgccgcactc aacccagaac ctcatcacta aaaggaacct catggt                   526



      <210> 2201
      <211> 396
      <212> DNA
      <213> Homo sapiens


      <400> 2201
 aagctgccta cacgcttctc ttgcacgctg agcttctgca gtggtctgac aagccctgtg     60
 tgcctcattt gcttcagagg gacagttact atgtttatac ccagcaagag cttaaagaga    120
 agctgtatca agaaatcata tcatatttcg acaaaggcaa aatgtgggag aaggccatca    180
 agctgagcaa agagttggct gagacttacg aaagcaaagt atttgactac gagggccttg    240
 gcaacctcct gaaaaaaagg gcctcatttt atgagaacat cattaaggca atgagtcctc    300
 agcctgaata ctttgctgtt ggatactatg gacagggctt tccttctttc ctacggaata    360
 aaatcttcat ctatcgggga aaggagtatg agaggc                              396



      <210> 2202
      <211> 507
      <212> DNA
      <213> Homo sapiens


      <400> 2202
 atgcctctta ctcatccgaa ccacggacca gacactctac agcgatggac atcctcccag     60
 actccaacat cactgagttc caaattaaat cctgaacccg aagcagacgc cgcatcgatc    120
 ctaatcgcca cctccatcct ttacaagcag agtgatccat accttgacat cctcgcacgg    180
 gtttatggtc cacctacggc ggccgaggag aacctaaaat gtttaaaaga gcaaggacaa    240
 gcgcatttac ggcatttcct actctgtaaa atggccgcgc ccatagccgt ggtcctgacg    300
 gcagccatgt ttgaaaattg gacgcacaga aggcagtggc aggtttttga gccaggagcc    360
 agggaagaag agaagtcact gaaatcgcct cgtttcctgg cacttaaagt cttgcgaaag    420
 ggggcagatt ttcagagact caggctttat caggcaaata tggggcaagc taaattgcct    480
 ttagcgcttt tccatccact ttgttaa                                        507



      <210> 2203
      <211> 1209
      <212> DNA
      <213> Homo sapiens


      <400> 2203
 ccatcactat aggctgcggg cacagtttct gtaggccctg cctctgtctt tgctgggaag     60
 aagcacacac tcctgccctg cgtgcaggga actgtcacag caggaagatt tcaaccaata    120
 ttcttctgaa gaatctagtg tccattgcca gaaaagccag tctctggcaa ttcctgagct    180
 ctaatgaaca aatgtgcggt atccacaggg agacaaagat gttctgtgat gtgggcaaga    240
 gcctgctctg ttttctgtgt tctaactctc aggaacactg gggcacagaa acactggctc    300
 actgaagggg cagctaagga acactgtgta agtgatgact cagagcactt tgaaagctgg    360
 agggcagcac agttgtttga atcagtggat gcagaaccca tgaatatgga gagtcaattg    420
 catttcatta tgcccaaagc tctcagaact aaaaaggcgg cttcagactc ctccaaagaa    480
 caagtggcca attcgaggga atcctccccg tcaccaaaag aagtaaacga cagtccgaga    540
 gccgccacca agtctcctga atcccagaat ctcatcgatg ggacaaaaaa accatcccta    600
 aagcaaccag acagtcccag aaacatctca agtgacaaca gcagcaaggg aaccccgtcc    660
 tctcctgcag gatccacaac agcaatcccc aaagtccgca taaaaaccat taagacatct    720
 tctggggaaa tcaagagaac agagaccagg gtatttccag aagtggatct tgactctggg    780
 aagaaacctt ccgagcagat ggtgtctgtg atggcctctg tgacatccct tctgtcatct    840
 ccagcatcag ccgctgccct ttcctctccc cccagggtgc ctctccagtc tgcagtggtg    900
 accaatgcag ttttccctgc agagcccacc cctaaacagg tcacaatcaa gcctgtggct    960
 actgctttcc tcccagtgtc tgctgtgaag acagcaggat cccaagtcat taatttgaag   1020
 cttgctaaca acaccacggt gaaagccacg gtcatacctg ctgcctctgt ccagagtgcc   1080
 agcagcatca tcattaaagc tgccaatgct atacaggagc aagctgtcat gatgccagca   1140
 tccagcctgg ccaatgccaa acttgtgcca aagactgtgc accttgccaa ccttaacctt   1200
 ctggcttag                                                           1209



      <210> 2204
      <211> 389
      <212> DNA
      <213> Homo sapiens


      <400> 2204
 acgcgtccga aatgtagatc atctacctgt aacctgaatg tttactggtg ccaaagccct     60
 ggtattgctg agtacctcat gagcaatgag tgaaaaaata ttgcgagaaa acagtgacca    120
 ggacagattc actcatatgc atcaactctc aggccgctga gagtaggctg tgtttttttg    180
 tcaacgatga gagctcatgg gactttcctc ataaaaggga gctggggtgt tgcagacctt    240
 tggttcgtct gagtctgtgt tctgcattga cgtagacaga gagttgctta tatttgcata    300
 ccagaacatc ttgctattcc ttaaaaataa aagagcctta atcttggaaa ctacatgctt    360
 tggatgggta ggcactgtaa aaagaacaa                                      389



      <210> 2205
      <211> 737
      <212> DNA
      <213> Homo sapiens


      <400> 2205
 tttcgtggag aaattgctga aaatctccct gaacaagata ttctgataca gagcgtctgt     60
 gagacgatgg tgccaaagct ggtggcagag gacatcccgc tgctcttcag cctcctgtcg    120
 gacgtgttcc ctggagtcca gtatcacagg ggtgagatga ctgcccttcg agaggagctg    180
 aagaaagtgt gtcaggagat gtatttgaca tatggagatg gagaagaagt tggtggaatg    240
 tgggttgaaa aggttctcca gctctatcag atcacccaga tcaatcatgg cctgatgatg    300
 gtggggccct cgggaagtgg gaagagcatg gcctggcgtg tcctgctgaa ggcattggag    360
 agactcgagg gtgtggaagg tgtggcccat atcatcgacc ccaaggccat cagcaaagac    420
 cacctctacg gaaccctgga ccccaacacc agggaatgga cagatgggct cttcacacac    480
 gtgctgagaa agatcatcga cagcgtgaga ggcgagctgc agaagcgcca gtggatcgtc    540
 ttcgatggcg atgtggatcc agagtgggtt gagaacttga actcagtgct ggatgacaat    600
 aagctcctaa ctttgcccaa tggagagcgc ctcagtcttc cacccaatgt gagaataatg    660
 tttgaggtac aggacttgaa atacgcgacc ttggccacag tgtcgcgctg cggcatggtc    720
 tggttcagtg aggatgt                                                   737



      <210> 2206
      <211> 405
      <212> DNA
      <213> Homo sapiens


      <400> 2206
 ttaaactaag aagttgggag cccagcaggc cctaggaaat atgaaaattg ctgctttgtt     60
 gggctgcatg atgatggcag ctcggtgtgg aactctctct gccatgagag atctgagttt    120
 ttcagatgaa aatcgccggc tggctgtagg cacggctgct gctgctgtga gcacacacaa    180
 aggcgtgtgg ctctggagcc tgtttgtctg tccctcaagg tctcttcttt gtttttgtaa    240
 ctgttccacc gaactgagag ccacagttgt tctcatacga tgctctgtac ttaaagggcc    300
 ttgttcaaaa gtcccagtta tacgggcagt aagcttgcat ggcagcaaca atgaatgcct    360
 gcaggtcgac tctagaggat cccaatgtgt cagtggagat ttcat                    405



      <210> 2207
      <211> 897
      <212> DNA
      <213> Homo sapiens


      <400> 2207
 atgcctggcc ccatgtccct ctggctcctc ctgctggttc tgccactgtc cctggagcac     60
 agtgatctca gaatttgctt ccccgggcag gtggtcagca tggaaagcag ctccacgggc    120
 ttcatctgga ctgatgtcag agcctggcag acatcaaatc ggcatgtttc ttcttggagg    180
 gaacccaggc attctcggat gccccctggg gccggcctca tggagcggat ccaggctatt    240
 gcccagaacg tctccgacat cgctgtgaag gtggaccaga tcctgcgcca cagtctgctc    300
 ctgcacagca aggtgtcaga aggccggcgg gaccagtgtg aggcacccag tgaccccaag    360
 ttccctgact gctcagggaa ggtggagtgg atgcgtgccc gctggacctc tgacccctgc    420
 tacgccttct ttggggtgga cggcaccgag tgctccttcc tcatctacct cagtgaggtc    480
 gagtggttct gccccccgct gccctggagg aaccagacgg ctgcccagag ggcacccaag    540
 cccctcccca aagtccaggc agttttccga agcaacctgt cccaccttct ggacctgatg    600
 ggcagcggga aggagtccct gatcttcatg aagaagcgga ccaagaggct cacagcccag    660
 tgggcgctgg ctgcccagcg cctggcacag aagctggggg ccacccagag ggaccagaag    720
 cagatcctgg tccacatcgg cttcctgacg gaggagtccg gggacgtgtt cagccctcgg    780
 gtcctgaagg gcgggcccct aggggagatg gtgcagtggg cggacattct gactgcactc    840
 tatgtcctgg gccatggcct gcgggtcaca gtctccctga aggagctgca gagatag       897



      <210> 2208
      <211> 15583
      <212> DNA
      <213> Homo sapiens


      <400> 2208
 gggcagcagc agtcagcgca cgccgagcgg ctgccggggg aagcagaggc gccggaggct     60
 ggggcaccgc cgacgcctcg ggagccatgg ccgaaggggg agaaggaggc gaggacgaga    120
 tccagtttct gaggactgag gatgaagtgg tactccagtg catcgccacc attcataagg    180
 agcagaggaa gttctgcctg gcagccgagg gacttgggaa tcgcctgtgc ttcttggaac    240
 ccacttcaga agccaagtac attcctccag atctctgcgt ctgcaatttt gtgctggaac    300
 agtccctatc tgtcagagcc ctgcaggaaa tgcttgccaa cacaggtgaa aatggcggcg    360
 aaggggcagc acaaggaggt ggccacagga ccctgttata cggccatgca gttctcctga    420
 ggcactcttt cagcggaatg tatctaacat gcttgactac atcaagatcc cagacagaca    480
 aacttgcctt tgatgtaggt ctacgggaac atgccacagg agaagcctgt tggtggacta    540
 tacatcctgc ttccaaacag aggtccgaag gagagaaagt tcgaattggc gatgacctca    600
 tcctcgtcag cgtgtcctct gaaagatacc ttcatctctc agtatcaaat ggtaacatac    660
 aagtggatgc ctcctttatg caaacactct ggaatgtaca tcctacgtgc tcaggaagta    720
 gcatcgaaga aggataccta cttggtgggc atgtagtacg tcttttccat ggtcatgatg    780
 aatgtttgac gataccatct acagaccaga atgattccca gcacaggagg atattctacg    840
 aagctggggg agctgggact cgagccaggt ctctttggag agtggaaccc cttcggataa    900
 gctggagtgg cagtaacatc agatggggcc aggctttccg actccggcat ctcaccacag    960
 gccactacct ggccttgaca gaagaccaag gccttatact gcaagaccgg gcaaagtcag   1020
 acaccaagtc cacagctttc tctttccggg catcaaagga actcaaggag aaattagact   1080
 ccagtcacaa gcgagacata gaaggcatgg gagttccaga aatcaagtat ggagattctg   1140
 tctgctttgt gcagcatata gccagtggtc tgtgggtgac ctacaaagca caagacgcca   1200
 aaacttcccg cctgggacct ctaaaaagaa aggtcatact ccatcaggaa ggccacatgg   1260
 atgatggatt aacactgcag agatgccaac gtgaggagtc ccaggctgct cggatcatcc   1320
 ggaacactac agccttattc agccagtttg tcagtggaaa caatcgcaca gctgccccca   1380
 tcaccctgcc tatagaagaa gtcctgcaga ccctacagga cttgatcgcc tacttccagc   1440
 ccccagagga ggagatgcga catgaagaca agcagaacaa gctccgctca ctcaaaaaca   1500
 gacaaaatct tttcaaggaa gagggaatgt tggcccttgt cttaaattgc attgaccgct   1560
 taaatgtcta caatagcgta gcacactttg cagggattgc aagggaagag agtggcatgg   1620
 cctggaaaga aattctgaac ctcctctaca aattgctggc tgctctcatt cgcggaaaca   1680
 gaaacaattg cgctcaattc tccaataacc ttgattggct catcagtaaa ttggacagac   1740
 tagaatcttc ctcaggtatc ttggaagttt tgcactgcat cttaactgaa agcccagaag   1800
 ccttaaatct gatagcggag ggccacatca agtcgatcat ctccctgttg gataagcacg   1860
 ggcggaatca caaggttctg gatatcctgt gctccctctg tctctgcaat ggggttgcag   1920
 tgagagccaa ccagaatctg atctgtgaca acttgctgcc ccggagaaac ctactcctgc   1980
 agacacgact gattaacgat gtaaccagta tccggccaaa catcttcctg ggagtcgcgg   2040
 agggctcagc ccagtacaag aagtggtact tcgagctgat tatcgaccag gtggacccct   2100
 tcctaacagc agagcccaca catctgcggg tgggctgggc ctcttcttca ggctatgccc   2160
 catacccagg aggtggagaa ggatggggag gcaatggtgt tggtgacgac ctgtactcct   2220
 atggctttga tggacttcac ctttggtcag gccggatacc cagagctgtg gcttccatca   2280
 accagcacct cctgagatcg gatgacgtgg gtaagctgct gcctggacct cgggggtgcc   2340
 cagcatctca ttccgcatca atgggcagcc cgtgcagggg atgtttggag aacttcaaca   2400
 cagacgggct cttcttccct gtgatgagct tttcagcagg tgtcaaagta cgtttcctga   2460
 tgggtggacg tcatggagag tttaagttcc tgcctccctc tggctatgcc ccttgctatg   2520
 aagccttact tccaaaagag aagatgagat tggagcctgt caaagaatat aaacgtgatg   2580
 ctgatggcat tagagatctc ttgggtacca cccagttcct ctcccaagcc tctttcatcc   2640
 catgccccgt agacaccagt caggttattt tgccacctca cctagaaaag atccgagaca   2700
 gactagctga aaacatccat gagctttggg gaatgaataa aatagaactt ggctggactt   2760
 tcggcaagat acgagatgac aataaaagac aacacccttg ccttgtggag ttttcaaagc   2820
 tcccagaaac tgagaagaac tataacctgc aaatgtcaac tgaaacctta aaaaccctct   2880
 tgaccctggg ttgccacatt gctcatgtta acccagctgc tgaggaggat ctcaagaagg   2940
 tcaaactgcc caaaaactat atgatgtcca acggctataa gccagcccct ttggatttgt   3000
 ctgatgtgaa gctgttacct cctcaagaaa ttttagtgga taagcttgca gaaaatgcac   3060
 acaatgtttg ggcaaaagac agaataaaac aaggatggac ctatggcatc caacaggatt   3120
 tgaagaacaa aagaaatccc cgtctggtgc catatgcatt actggatgag cgtaccaaga   3180
 agtcaaacag ggacagcctg cgggaagctg tgcgcacttt tgttggttac gggtataaca   3240
 ttgagccatc agaccaagaa ctagctgact cggctgtgga gaaggtcagc atagacaaga   3300
 tccgattttt ccgggtagag cgatcttatc cagtgagatc tggaaagtgg tattttgagt   3360
 ttgaagtggt gactggagga gacatgcgag tcggctgggc gaggccaggc tgtcgacctg   3420
 atgtcgagct gggggccgat gaccaagcct ttgtgtttga aggcaacagg ggccagcgtt   3480
 ggcatcaagg aagtgggtat tttgggcgta cctggcagcc aggggatgtg gtcggatgta   3540
 tgattaacct ggatgatgct tcaatgatct tcacactgaa tggggagctg ctgatcacca   3600
 acaaaggctc tgaacttgcc ttcgctgact acgagattga gaatggcttc gtgcccatct   3660
 gctgtctggg tctatctcag atcggccgca tgaatctcgg gacagatgcc agtaccttca   3720
 agttttatac catgtgcggt ctccaagagg gctttgagcc ttttgctgtc aacatgaaca   3780
 gagatgttgc tatgtggttc agcaagcgcc tcccgacgtt tgtcaacgtg ccaaaggatc   3840
 atccacacat agaggtcatg aggattgatg gcaccatgga cagccctccg tgtctcaagg   3900
 tgacgcataa gacatttggc acacagaata gcaatgccga catgatctat tgccgcttga   3960
 gcatgcctgt cgagtgccac tcctccttca gtcacagccc ctgtctggac agtgaagctt   4020
 tccagaaaag gaaacagatg caagaaatac tctctcatac aacaacacag tgctactacg   4080
 ccatccgcat ctttggtgga caggatccat cctgtgtctg ggtcggatgg gtgactccag   4140
 actatcactt gtacagtgaa aagtttgacc tgaataaaaa ctgcacagtg actgtcaccc   4200
 taggggatga aagaggccgg gtccatgaaa gtgtgaaacg cagcaactgc tacatggtct   4260
 ggggtggaga cattgtagcc agttcccaga gatcaaatcg gagcaacgtg gacctggaga   4320
 tcggctgtct cgtggatctg gccatgggca tgttgtcctt ctcagccaat ggaaaggaac   4380
 tgggcacctg ctaccaggtg gagcctaata ccaaagtgtt tccagcagtc ttcctgcagc   4440
 ctacaagtac ttctttgttt cagtttgaac ttggaaagct gaagaacgca atgcccctgt   4500
 cagcggccat attcaggagt gaagaggaga acccagtccc acagtgtcca cctcggctgg   4560
 acgtccaaac catccagccc gtgctctgga gccgcatgcc caacagcttc ctgaaggtgg   4620
 agaccgagcg tgtgagcgag cgccacggct gggtggtgca gtgcctggag cccctgcaga   4680
 tgatggcgct ccacatcccc gaggagaaca ggtgtgtgga tatcctggag ctctgtgagc   4740
 aggaggacct gatgcggttc cattaccaca cgctgaggct ctacagcgcg gtgtgcgccc   4800
 tgggaaacag ccgcgtggcc tacgccctgt gcagccacgt ggacctctcc cagctcttct   4860
 atgccattga caacaagtac ctccccggcc tccttcgatc tggtttctat gacctgctca   4920
 tcagcatcca cctggccagc gccaaggaga ggaagctgat gatgaagaac gagtacatca   4980
 tccccattac cagcaccacc aggaatatct gcctcttccc ggacgagtcc aagaggcatg   5040
 gactgcctgg ggtgggcctg agaacatgtc tcaagcccgg gttcaggttc tccacccctt   5100
 gctttgttgt gactggtgag gatcaccaaa agcagagccc cgagattccc ttggagagtc   5160
 tcaggacgaa ggctctgagt atgctgacag aggcagtgca gtgcagcggg gcccacatcc   5220
 gagaccctgt aggggggtct gtggagttcc agtttgtgcc tgtgctgaaa ctcattggaa   5280
 ccctgctggt catgggcgtg tttgatgatg atgatgttcg gcagatcctc ctcctgattg   5340
 atccctctgt gtttggggag catagtgcgg ggacagagga gggagcagaa aaggaggaag   5400
 tgacccaggt ggaggagaag gctgtggagg ctggggagaa ggccggcaag gaggctcctg   5460
 tcaaaggctt gttgcagact cgattacccg aatccgtcaa gctgcagatg tgtgagctcc   5520
 tcagctatct ctgcgactgt gagctgcagc accgagtgga ggccattgtg gcatttggtg   5580
 acatttatgt ctccaagctg caggcaaatc agaagttccg ctacaatgag ctcatgcagg   5640
 ccctgaacat gtctgcggcc ctgactgccc ggaagaccaa ggagttccgc tcacccccac   5700
 aggagcagat caacatgctg cttaactttc aactgggaga gaactgcccc tgcccagagg   5760
 agattcggga ggagctgtat gatttccatg aggaccttct ccttcactgt ggggttcctt   5820
 tggaagaaga ggaagaggag gaggaggaca cctcctggac aggaaaactc tgtgccttgg   5880
 tttacaaaat caaaggccca cccaagccag agaaggagca gccgacggag gaggaggaga   5940
 gatgccccac aacattgaag gaactcatct cacagacgat gatctgctgg gcccaggagg   6000
 accagatcca ggattcagag ctggtccgaa tgatgttcaa cctcctccgg aggcagtatg   6060
 acagcattgg ggagctgctg caggcgctgc ggaagaccta caccatcagc cacacctctg   6120
 taagcgacac catcaacctg ctggctgccc tgggccaaat ccgctccctc ctcagtgtca   6180
 ggatgggcaa ggaagaggag ttgctcatga tcaatgggct gggagacata atgaacaaca   6240
 aggtgtttta ccagcatccc aacctcatga gagtcctggg catgcacgag acggtgatgg   6300
 aggtgatggt gaacgtgttg ggtacagaga aatctcagat tgcatttcca aagatggttg   6360
 ctagctgctg ccgtttcctt tgctatttct gtcgaattag ccggcaaaat cagaaggcca   6420
 tgtttgagca tctgagttat cttctggaga atagcagtgt tggcctagcc tccccgtcga   6480
 tgaggggatc caccccgctg gatgtggcag cttcctctgt gatggacaac aatgagttag   6540
 cgctgagctt agaggaacca gacctcgaga aggtggtgac ctacttggca ggctgtggcc   6600
 tacagagctg ccccatgctt ctggccaaag gataccctga tgtcggctgg aaccccattg   6660
 aaggggaacg ctacctgtcc ttcctgaggt ttgctgtctt cgtgaacagt gagagtgtgg   6720
 aagaaaacgc cagcgttgtg gtcaagctgc tcatcagacg cccagagtgc ttcggcccgg   6780
 ccctgcgggg tgagggggga aacggactct tggcagccat gcagggtgcc attaagatct   6840
 ctgagaaccc agcgctcgac ctcccctctc aaggatacaa aagagaagtc agcacggagg   6900
 acgatgaaga ggaagaagaa atcgtgcata tgggcaatgc aattatgtca ttttattcgg   6960
 cccttataga tctactgggc cgctgtgctc ctgaaatgca cctcatccag acaggaaagg   7020
 gggaagccat ccgcatcagg tccatcctgc gctccctggt ccccacagaa gacctggttg   7080
 ggatcatcag catccccttg aaactgccct ccctcaacaa agatgggtcg gtcagtgagc   7140
 cagatatggc gggcaatttc tgccctgacc acaaggcacc tatggtgctg ttcttggacc   7200
 gcgtttatgg cattaaggat caaacttttc tgctccactt gctggaggtt ggatttttac   7260
 ctgacctaag agcttctgcc tctctagata cagtttccct aagcaccaca gaggctgcgc   7320
 ttgcactaaa taggtatata tgttctgctg tgctcccgct cctcacaaga tgtgcccctc   7380
 tctttggcgg aacagaacac tgcacctctc tgattgattc cacactgcag acaatataca   7440
 ggctatccaa gggacgttcc ctcaccaaag cacaaaggga cactatagaa gaatgtttgc   7500
 ttgccatttg caatcacttg aggccttcca tgttacagca actcctgcga cgcctcgttt   7560
 ttgatgtgcc gcaactcaat gaatactgca aaatgcctct caagcttctg acgaatcact   7620
 atgaacagtg ttggaagtat tactgcctgc cttcaggatg ggggagctac gggctagctg   7680
 tggaagaaga gctgcaccta acggagaagc ttttctgggg gattattgac tcgctctccc   7740
 ataagaaata tgacccagat cttttccgaa tggccctgcc ttgtctcagt gctatagctg   7800
 gggccttgcc accagattat ttagattcca gaatcacagc cacgttggag aaacagatct   7860
 cagtggatgc ggatggcaac tttgacccaa aacctattaa caccatgaat ttttccttgc   7920
 ctgaaaaatt ggaatacatc gtcaccaagt atgctgagca ttcacatgat aaatgggcct   7980
 gtgacaagag tcagagtgga tggaaatatg ggatttccct ggatgaaaat gtgaagaccc   8040
 acccactgat aaggcctttc aagacattaa cggagaagga gaaggaaatt tatcgctggc   8100
 ctgcgcgaga gtccctgaaa accatgctgg ctgtgggctg gactgtggag aggaccaaag   8160
 agggagaagc tttggttcaa cagcgggaaa atgagaagct tcgaagtgtg tcccaggcca   8220
 accagggcaa cagctacagt cctgctcccc tcgacctctc aaacgttgtg ctctccagag   8280
 agctccaggg aatggtggag gtcgtggctg agaactatca caatatctgg gccaagaaga   8340
 agaagctgga gctggagagc aaaggtggtg gcagccaccc tcttctggta ccatatgaca   8400
 ccttgactgc caaggaaaag ttcaaggacc gggagaaggc acaggacctg tttaagttcc   8460
 tccaagtgaa tggcatcata gtttccaggg gtatgaagga tatggagctg gatgcctcct   8520
 ccatggagaa gaggtttggc tataagttct tgaagaagat cctgaaatac gttgattctg   8580
 ctcaagaatt tattgcccat ttagaagcca ttgtcagcag tgggaaaact gaaaagtctc   8640
 cccgtgacca ggagatcaaa ttctttgcca aagttctcct cccgctggtt gaccagtact   8700
 tcaccagtca ttgcctctac ttcttgtcat cccctctgaa gccccttagc agcagcggat   8760
 atgcctccca taaggagaaa gaaatggtgg ccggcctgtt ctgcaaactt gccgctctcg   8820
 ttagacacag aatttccctc tttggtagtg attctactac aatggtgagc tgtcttcaca   8880
 tcttagctca gacacttgac acaaggactg tcatgaagtc aggctcagag ctggtgaagg   8940
 ctgggttacg agcattcttt gaaaatgctg cagaagattt ggagaagact tcagaaaacc   9000
 tgaaacttgg gaagttcacc cattcccgaa cgcagattaa aggcgtttct cagaatatta   9060
 actacactac agtggctctg ctccccatcc tgacgtccat ctttgagcac gtcactcagc   9120
 atcagtttgg aatggatcta ctcttgggtg atgtgcagat ttcatgctac cacatactgt   9180
 gcagcctcta ctcccttggg acgggaaaga acatttatgt tgaaaggcaa cgccctgccc   9240
 ttggagaatg tctggcctcg ctggcagctg ccataccagt ggcattcctg gagcccaccc   9300
 ttaatcgcta caatccactc tcggtcttca acaccaaaac ccccagggag aggtctattc   9360
 tggggatgcc agacacggta gaagacatgt gtcctgacat cccccagctg gaaggcctga   9420
 tgaaggaaat caacgacctg gccgagtcag gggcccggta cacagagatg ccccatgtca   9480
 tcgaggtgat cttacccatg ctctgcaact acttgtccta ctggtgggag cggggtcctg   9540
 agaacctgcc ccccagcaca gggccatgct gcaccaaggt cacctctgaa cacctcagtc   9600
 tcatcctggg caacattctg aaaatcatca acaacaacct gggcatcgat gaggcctcct   9660
 ggatgaagcg cattgcagtg tatgcacagc ccatcatcag caaagccagg cccgacctgc   9720
 tgagaagcca cttcatccca actctggaga agctgaagaa aaaggctgtc aagacggtgc   9780
 aggaggagga gcagttgaaa gccgatggca aaggggacac ccaggaggca gaactcctca   9840
 tcctggacga gttcgcggtc ctctgcagag atctctatgc cttctacccc atgctgatcc   9900
 gctacgtgga caacaacaga tctaactggc tgaaaagtcc tgatgctgat tctgaccagc   9960
 tcttccgcat ggtggcagaa gtcttcattc tgtggtgtaa atctcataac ttcaagagag  10020
 aagagcaaaa ttttgtgatt cagaatgaaa ttaataattt ggcattttta actggagaca  10080
 gcaaaagcaa gatgtcaaaa gccatgcaag taaagtctgg aggacaagac caggagcgga  10140
 agaagacaaa gcggcgggga gacttgtatt ccatccagac ctccctcatc gtggctgcac  10200
 tcaagaaaat gctgcccatt ggtttgaata tgtgtactcc aggcgaccag gagctgatct  10260
 ccctcgcaaa atcgcgatac agccataggg acacagatga agaggtcaga gaacatctgc  10320
 ggaacaactt gcacttgcag gaaaagtctg atgacccagc tgtaaaatgg caactgaacc  10380
 tctacaagga tgttctgaag agtgaagaac ctttcaatcc ggaaaagaca gtggagcgtg  10440
 tgcagagaat ttcagcagct gtcttccacc tggaacaggt ggaacagcct ttgaggtcca  10500
 agaaggccgt ctggcacaaa ctgttatcaa agcaacggaa acgggcagtg gtggcctgtt  10560
 tcaggatggc ccctctctac aacctgccca ggcaccgctc tattaacctc ttcctccatg  10620
 gctatcagag attttggata gaaacagagg agtattcctt tgaagagaaa ctagtacagg  10680
 atttggctaa atctccaaag gtggaagagg aggaggagga agagacagaa aaacaacctg  10740
 acccactaca tcagatcatt ctctatttta gccgcaacgc tctcacggag aggagcaaat  10800
 tggaagacga ccctttgtac acctcctatt ccagcatgat ggccaagagt tgtcaaagtg  10860
 gtgaggatga agaagaagat gaagacaagg aaaaaacatt cgaagagaaa gagatggaga  10920
 agcaaaaaac cctctatcag caagctcggc tgcatgagcg tggtgctgcg gagatggtcc  10980
 ttcagatgat aagcgctagc aaaggtgaga tgagccccat ggtggttgag acgctgaagc  11040
 tggggatcgc cattctgaac ggaggcaatg ctggtgtgca acagaaaatg ctagattacc  11100
 taaaggagaa aaaggatgct ggattctttc aaagcctttc tggtcttatg cagtcttgca  11160
 gtgtccttga tttgaatgca tttgagaggc agaataaagc tgaaggcctg gggatggtga  11220
 ctgaagaagg aacactcatt gttcgggaac gtggtgaaaa agtactccag aatgacgagt  11280
 tcacgcgtga tctctttaga ttcctacagt tactttgtga gggacataac agtgactttc  11340
 agaacttcct gcggactcag atgggcaaca ccaccaccgt gaatgtcatc atcagcactg  11400
 tggactacct tctgcgtctg caggaatcaa tcagtgattt ctactggtat tattcaggga  11460
 aggacatcat tgatgaatct ggacagcaca atttttccaa agctctggca gtcaccaagc  11520
 agattttcaa ttctcttaca gaatacatcc agggcccttg cattggtaat caacagagcc  11580
 tggctcacag caggctgtgg gacgcagtgg ttggcttcct ccatgtcttt gctaatatgc  11640
 agatgaaact ctctcaggat tccagtcaga tcgagctgct gaaggaactc ttggatctcc  11700
 ttcaggacat ggtggtgatg cttctgtccc tcctggaagg gaatgtggta aatggcacca  11760
 ttggcaagca gatggttgac acactggtag aatcatctac caatgtagaa atgatcttga  11820
 aattctttga catgttcttg aaacttaaag acttaaccag ctcagacacc ttcaaagaat  11880
 atgacccaga tggtaaagga attatctcca aaaaagaatt ccagaaggcc atggaagggc  11940
 aaaaacagta cacgcagtca gagattgact ttctcctgtc gtgtgcagaa gctgatgaga  12000
 atgacatgtt taattacgtt gattttgtag accggttcca tgagccagcc aaggacatag  12060
 ggtttaatgt ggctgtgtta ttgacaaatc tttctgaaca catgccaaac gattcccgcc  12120
 tgaagtgtct gttggaccca gcagaaagtg tgctaaatta cttcgaaccc tacctaggac  12180
 gcatcgagat catgggtggg gccaagaaga ttgagcgtgt ttattttgag atcagtgaat  12240
 ccagtcgcac tcagtgggag aagccccagg tgaaggaatc taagcgacag ttcatttttg  12300
 atgttgtcaa tgaaggtggg gagcaggaaa agatggagct gtttgtgaac ttctgtgagg  12360
 acaccatctt tgaaatgcag ttagcatctc agatctctga atccgattca gctgacaggc  12420
 cagaagagga ggaagaagat gaagattctt cttacgtgtt agaaattgcg ggtgaagagg  12480
 aagaagacgg gtctcttgag ccggcctctg catttgctat ggcctgtgcc tctgtgaaga  12540
 ggaatgtcac cgacttcctg aagagagcaa ccctgaagaa cctcaggaag cagtacagga  12600
 acgtgaaaaa gatgactgcg aaggagctgg tgaaggtgct cttctccttt ttctggatgc  12660
 tgttcgtggg gctattccag ttgctcttca ccatcctggg aggaatcttt cagatcctct  12720
 ggagcacagt gtttggaggg ggcctggtag aaggggcaaa gaacatcaga gtgaccaaga  12780
 tcctgggtga catgcctgac ccaacccaat ttggtatcca tgatgacact atggaggctg  12840
 agagggcaga ggtgatggag ccaggtatca ccactgaact agtacacttc ataaaggggg  12900
 agaagggaga tacagatatc atgtcagacc tctttggact ccacccaaag aaagagggca  12960
 gcttaaagca tgggcctgaa gtgggtttgg gtgacctctc agaaattatt ggcaaggatg  13020
 aaccccctac attagagagt actgtacaga agaagaggaa agctcaggca gcagaaatga  13080
 aagcagcaaa tgaagcagaa ggaaaagtag aatccgagaa ggcagacatg gaagatggag  13140
 agaaggaaga caaagacaaa gaagaggagc aagctgagta cctgtggaca gaagtgacaa  13200
 aaaagaagaa gcggcggtgt ggtcagaagg ttgagaagcc ggaagctttc acagccaatt  13260
 tctttaaagg gctggaaatc tatcagacca agttactgca ttacctggcc aggaatttct  13320
 acaacctgag gttccttgct ctgtttgtag ccttcgctat caacttcatc ctgctttttt  13380
 ataaggtcac tgaagaacct ttagaagaag agacagagga tgttgcaaac ctatggaatt  13440
 cctttaatga cgaggaagag gaagaagcga tggtattctt tgtccttcag gagagcaccg  13500
 ggtatatggc accaaccctg cgtgccctgg ccatcatcca taccatcatc tctctagtct  13560
 gtgtggtggg ctactactgc ctgaaggtgc ctttggtggt tttcaaaagg gaaaaagaaa  13620
 tcgccaggaa gctggagttt gatggcctat atatcaccga acagccatct gaagatgaca  13680
 tcaaggggca gtgggaccgc ttggtgatca acacaccatc ttttcctaat aactactggg  13740
 acaagtttgt aaagagaaag gtgatcaaca agtatggaga tctctacgga gcagaacgca  13800
 ttgctgaact tctgggtttg gacaaaaatg ctcttgactt tagcccagta gaagagacca  13860
 aagcagaagc ggcttctctg gtgtcatggc taagttccat agacatgaag taccatatct  13920
 ggaagcttgg agttgttttt actgacaact cctttctcta ccttgcctgg tatacaacca  13980
 tgtcagtcct gggccactac aataacttct tctttgctgc tcacctattg gacatcgcaa  14040
 tgggcttcaa gacactgagg accattctgt catctgtaac tcacaatggc aaacagttgg  14100
 ttctgactgt cggtctcctg gccgtggtgg tttatctcta tactgtggtg gctttcaact  14160
 tcttccgcaa gttctacaac aaaagcgaag acgatgacga gcccgatatg aagtgcgacg  14220
 acatgatgac gtgttacctt ttccacatgt acgtgggagt gagagcagga ggtggcattg  14280
 gtgatgaaat tgaagaccct gctggtgatc cttatgaaat gtatcgcatt gtctttgaca  14340
 ttaccttttt cttcttcgtc attgtcatct tgctggccat cattcaaggt cttattattg  14400
 atgctttcgg agagctaaga gaccagcagg aacaagtacg agaagatatg gagactaaat  14460
 gtttcatctg tgggattggc aatgactact ttgacacaac ccctcatggt tttgaaacac  14520
 atacattaca agagcacaac ttagccaact acttgttctt tctgatgtat ttgattaata  14580
 aagatgaaac agagcacacg ggtcaggaat cttatgtctg gaagatgtac caagaaaggt  14640
 gttgggattt cttcccagcc ggtgactgct ttcgtaaaca atatgaagat cagcttggat  14700
 aaatctgaat caaagaagcg cgacaattct ggacagtcaa cttcccatga aataaagtcc  14760
 cctttttaca gttctgcaac atatctgaaa tgtgacattt tctaaatgcc tcccttaaaa  14820
 aaaaaactgc tgaaaatctg tgctattttg aaattgattt ggctttttgt gcctaatgga  14880
 catacactgt gggagagaac ctgtcaaaat gtcgaagaag gaaggcgaag aatcaagtaa  14940
 tctctaggca aatgccttca agttttccag ttctgaggta actagttcag tttgttggga  15000
 tggaagcatg aaggaaaggg ctagagaagt atgaaatctc gaatgtgtaa tacctgaaaa  15060
 tttaaacact tgaatgtcat catggtatcc aacttgtgac tcatagggtc tgaactcact  15120
 ccaaaagata ataactgcag tctaattttt cccatggtac ttgctagtga ctgtatccag  15180
 aaaagcttta agcagttaaa gaaacagaaa aaaaccgaca ctttgtcgac actgaaatat  15240
 cgattaagtg ccttaaaacc tctttagaca tagctatgca agttttttat gtttgtgttc  15300
 cagaaggaca gttccattca ttagttgtga tcttccgtct tactttatga aactgcactt  15360
 gaaggttatt catacaagtt tttttagtaa cagctgtcag tcaactgctg ttattagaag  15420
 aaaagtactg tactgaaaat tcagaaaaaa aaatctcaac cttatgccaa aatggagtaa  15480
 tgctttatgg tcccttgtaa gtagtggagc tgctctgttt aggtgaatct cctcaaatac  15540
 aatgaagtgc ccactgcaat aaagtaatac gtaccaataa aaa                    15583



      <210> 2209
      <211> 428
      <212> DNA
      <213> Homo sapiens


      <400> 2209
 atttcgtgga cgaagcagtt gctgtgggag gtgtggtaac tgctggaagg aagatgctca     60
 attcttctga gcaacgaagg ccacacggag tcctggattc tgtgtggcct ggcatccatg    120
 gcgcactgtg tgctggcagg tggctcagga cggggcagtt atcatgggac acccgccata    180
 tgctggcaag gaagatggtc agttcttctg agccacaaag gcccccaaca tcctggagtt    240
 ggtgttgcct agcatccacg gtgcgccccc tgctggtgga tggctcagga tggggcagtt    300
 gccgtgggag gcccgctgcc tgctggaagg aagatggtca gttcttctga accacaaagg    360
 ccctgcagag tcctggagtc tgtgtggcct ggcttccagg gttcacctca tgctggtgga    420
 ttgctcaa                                                             428



      <210> 2210
      <211> 1038
      <212> DNA
      <213> Homo sapiens


      <400> 2210
 tttcgtgtgc gcgctctccg cctgatagga gttgtagttc tgcgggtgaa gctcggcgtt     60
 actatcaagc aaccaaactg caagctttgg gagttgttcg ctgtccctgc cctgctctgc    120
 tagggagaga acgccagagg gaggcggctg gcccggcggc aggctctcag aaccgctacc    180
 ggcgatgcta ctgctgtggg tgtcggtggt cgcagccttg gcgctggcgg tactggcccc    240
 cggagcaggg gagcagaggc ggagagcagc caaagcgccc aatgtggtgc tggtcgtgag    300
 cgactccttc gatggaaggt taacatttca tccaggaagt caggtagtga aacttccttt    360
 tatcaacttt atgaagacac gtgggacttc ctttctgaat gcctacacaa actctccaat    420
 ttgttgccca tcacgcgcag caatgtggag tggcctcttc actcacttaa cagaatcttg    480
 gaataatttt aagggtctag atccaaatta tacaacatgg atggatgtca tggagaggca    540
 tggctaccga acacagaaat ttgggaaact ggactatact tcaggacatc actccattag    600
 gcacagtgaa cgtgggtcaa ctaatcaaag aagtgaaaaa gtttgagaaa gtaatcgtgt    660
 ggaagcgtgg acaagagatg ttgctttctt actcagacaa gaaggcaggc cccatggtta    720
 atcttatccg taacaggact aaagtcagag tgatggaaag ggattggcag aatacagaca    780
 aagcagtaaa ctggttaaga aaggaagcaa ttaattacac tgaaccattt gttatttact    840
 tgggattaaa tttaccacac ccttaccctt caccatcttc tggagaaaat tttggatctt    900
 caacatttca cacatctctt tattggcttg aaaaagtgtc tcatgatgcc atcaaaatcc    960
 caaagtggtc acctttgtca gaaatgcacc ctgtagatta ttactcttct tatacaaaaa   1020
 actgcactgg aagattta                                                 1038



      <210> 2211
      <211> 405
      <212> DNA
      <213> Homo sapiens


      <400> 2211
 tttcgtccgg cgagggagga agaagcgcga agatccgtta gtcatgccgg tgtggtggcg     60
 gcggcggaga ctgcgggccc gtagctgggc tctgcgaggt gagagtgatc gcggtcttag    120
 gtccaactcc tctacgtgcc gggttcctcc gccatatggg tgcccagcgc ggcccctgtc    180
 ccttccccgg gcgcagcgga gcgggcggct gctgcgtagg ccaaaaggct acgctcccgg    240
 tgcccccaag gcccacgagc tttccccaca agccatttgc gcagtcgcgt tttgtgagta    300
 accacctgga aggcttagct gacctttctc cgtcaacacc ggttcgctgt cctctgctca    360
 gaaactgggc aagggccttc tgacttaagg aggtgcctgc aaggg                    405



      <210> 2212
      <211> 495
      <212> DNA
      <213> Homo sapiens


      <400> 2212
 ccagtctctg acttaattgg tataggcaag gatccaagca tggttatttt aaacgctctc     60
 cagaggagag cattcttatg tgcagccaat gttaagatcc ccagattgag aataaaagtt    120
 aaaacaaaag aagctagtgc tcaggtagtc aaagaagagt gcaataagta cttgctgttc    180
 cttcttcctg ttccttccgc tggccttctt ccctcaatta tggaaatagc tgatcccttt    240
 tcatcattcg ggtctgagga caaatgttat accctcacac cgcccctccc gcgacatact    300
 gagaaatcga gtgactctca agagaaaggc cattttgagg ctggggtcga accaaaatcc    360
 agggggtcca caccaggtca gtaccccgga attggctgtt ttgcaagatt tcgggagtac    420
 caaattggca tgagacattt gacaacgagg ccagccatgc accgagctca ggttttattt    480
 ccgttgtcct tctga                                                     495



      <210> 2213
      <211> 726
      <212> DNA
      <213> Homo sapiens


      <400> 2213
 tcccgttgac gtcggtacgc acgcacgacc ggaccggaat tcccggggcg acgatttcgt     60
 ggcttcctgc atttggcggg gtctttgttt ctcgctggcg ctggcacagg aacttgggat    120
 ttggctcctc tttcgcctcc tgcaccttgg gagccctggg ctactctttc acagcccctg    180
 ttgccctgtg atctgtaggt ccttggggac gcacagttaa gatgacagga catcctggaa    240
 gctgggaaat ggtgagtata cggggttcgg catcccgaga ggggagagca ggctgtgaaa    300
 ccggcaggac cggcctcccc acggttagct ccgagtctcc cgcagcttgg ccctcagtcc    360
 cctgtggctg caagatggcc gctgggccag cagcgaggac ccccacatcc ggcctggccc    420
 atccggtcct gtccctgggc agcgccctgc tctgcgccca cagccatgag tatttcccag    480
 attgttcagg gaggcctggt gggtcatcag ggaaaaaccg cgactgggtg tttgcgtggg    540
 aggagctgcg gcccgtgggg tccccagtct ctcttgttaa aaattaacgg gagtcctatg    600
 ttaaaacgtt aaccagttta tctggaacaa acagtgattg gtgaaatgga aagcacccag    660
 ccatgtattt ctggtccacc agaggggtca taaaggaaag gctttcatga agatgcatga    720
 gaaagc                                                               726



      <210> 2214
      <211> 1938
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1938)
      <223> n = a,t,c or g


      <400> 2214
 cgagcccgga gacttgcctt gcaatgccat gtttgtgtat gtgctctaac tcccggagag     60
 caatcaggga gacggctccc cggccagact tggctgatgt tttcttgttt ctgtttcagc    120
 cttcaggata attccttcag cagcaccact gtaacagagt gtgacgaaga tccagtctct    180
 ctacatgaag accagactga ttgctccagt ctcagagatg aaaacaataa agagaactac    240
 cccgacgcag gggctctggt agaagagcac gcgccgccct cttgggagcc gcagcagcag    300
 aatgtagagg cgaccgtgct ggtggacagc gtattgcgac ccagcatggg caacttcaag    360
 tccaggaagc ccaagtccat cttcaaagcg gagagcggga ggagccacgg agaaagtcag    420
 gagacagagc atgtggtatc cagccagtca gagtgtcagg tgagagcagg aacaccagct    480
 catgagagtc cacaaaacaa tgccttcaag tgccaagaaa ccagtgcgac ttccaaccaa    540
 gaatagacca gaggactgcc acttcgccaa aggatgcttt tgaaactcgg ccaggactta    600
 aatgaggaag aagctgctca ggtgcatgga gtcaaggacc cggcgccagc atcaacccag    660
 agcgtgcttg ccgaatggga cagattctgc agacccctca ccagtccaca aagatgggca    720
 gaatgaggcc gacagtgcac cagaagacct ccactctgtg gggaccagca ggctgcttct    780
 attcacatca ctgatggtga taaccccact gctgttcgcc acggttgttc cctctttcag    840
 gccaaagcca gagattcaac ttagaccccg agtcagcccc atctccaccc agcactcagc    900
 agtttatgat gccgcggagt tcttcacgct gcagctgtgg agatggcaag gagccacaga    960
 ccatcaccca gctcaccaag cacatccaga gcctcaagcg gaaaattcgg aaatttgaag   1020
 aaaaatttga acaagaaaag aaataccggc cttcacatgg tgacaagact tctaatcctg   1080
 aagtcctgaa atggatgaat gatttggcta aaggtcgtaa acagctcaaa gaactaaagc   1140
 taaagctgtc agaagaacaa gggagtgctc ccaaaggtcc acctagaaac ctgttgtgtg   1200
 agcaacccac agtccccaga gaaagtggga aaccggaagc tgcgggcccg gagccaagct   1260
 cctctggaga agagactcca gatgctgcct tgacatgcct gaaggagaga agagagcaac   1320
 ttcctcccca ggaggattct aaggtaacta agcaagacaa gaacctcata aagccgcttt   1380
 atgaccgata cagaattatc aagcaaatct tgtcaacacc ttcccttatt ccaacaattc   1440
 aggaggaaga ggactctgat gaagaccgtc cacagggaag ccaacaacct tctttggcag   1500
 atccagcatc tcaccttcct gttggtgacc acctcaccta ctctaatgag actgagcctg   1560
 ttagggccct tttaccagat gaaaagaaag aagtaaaacc accagctctc tccatgtcta   1620
 atttacatga ggctaccatg cctgtacttc ttgaccatct ccgagaaact agggctgaca   1680
 agaagagact gcggaaagcc ttaagagaat ttgaagaaca gttttttaaa caaacaggaa   1740
 gaagtccaca aaaggaagat aggataccaa tggcagatga gtattatgaa tataagcaca   1800
 taaaggccaa actgagactt ttggcccccc cagccggatc atatttcccc cntgnnnnnn   1860
 nnnnnnnnnc ggnaaatgtt atgatcactt tcacccatga tataaagtaa agtttatttt   1920
 cctctgcaaa aaaaaaaa                                                 1938



      <210> 2215
      <211> 585
      <212> DNA
      <213> Homo sapiens


      <400> 2215
 ttaagaaaat aaattgggat gcaaattgag aaagatatgt ctcatttaaa tttttttcta     60
 ccatttacag aacttgaagg tctcttcaca gactaatttc ttatctcgag catggtggtt    120
 ccccatcttt tatttttttg agaaaaatgt acaaggctca attccttgct gcttctcctg    180
 gccgctgtct tggcctcctg gctgcttcaa atcatcatgc aaaaagtatt cacgggttca    240
 gaagattggt gaagacaatg agaaatcgac tctgttctct gtgccagccc tttcctttgc    300
 caaagcactt gctgtctctg agttggttcg gtgaccaggg tcatacttcc caatacttca    360
 ctctttccac acagagaaat gaagcacaac tccaataaca gggtgagggt gcaagtcagg    420
 gaccacagaa gtcactactg ggctcctgaa agcccaaggc cacatttggg aaacgatctg    480
 cacttctggc aaaagtgcaa gaggggcagt ggtggcccca gaagaaatat tttaataaag    540
 aagatacacg aatggctaat aagcacataa aaatgctctc gtgcc                    585



      <210> 2216
      <211> 1830
      <212> DNA
      <213> Homo sapiens


      <400> 2216
 atgagcaagg gtgaaagtag aaaatgcaat gaggaaaatg tatccaagtc ttcaaaggtc     60
 gtgaaggtgt ttattgtcct gaccccacag tttctgtccc gtgacaagga ccagctgacc    120
 aaggagctgc agaagcatgt aaagtcagtg acagtctcat gcaagtcccc aaggaagctc    180
 ctgagtcaca tcacacggct acatccacct tcaaagggtc aaggggagaa cctgacacac    240
 ttggtggatt ccattaaggc gaccatatgg tgtcagcctg tgtgggagac tgtggagggg    300
 cagaggagga gggtagggaa ttgcattgac ttcactaatg gatgtgacct ggttggcagc    360
 agcagcttgc acaacatgct tgtttgcagc tcatatgaca ttaacagaca agacactttt    420
 cagaaagaca ggacttctga gaagcacctt ctggacagcg tctttactgc cctccaggac    480
 tcagctggtc agcaatggcc agccagactc catccccagc gtggagagga ggtagctgat    540
 cccagaggcg ctcctagcag gcatgtggaa cccgagaaca gctcgccctg ccaaggcaat    600
 ggagagcagg ccggcaaggc aggagctcgg gctctgtgtg gccaggcaag gaggagcccc    660
 gcaaccatgc caccacccct tactacaaga agcctctgcg agtttgccgt cttcctcctc    720
 cactggctct tccctgagct cttccactac cgcaagctgg gcgagcagga cagctgctac    780
 ggggacggcg gcaagcagga gctggacccg cagaggctgc agatcatctg caacttcacg    840
 gaggtctact tcccccacat gcaggaggag gaggcctggc ggcaagcagg acctggaccc    900
 gcagaggctg cagatcatct gcaacttcac ggaggtctac ttcccccaca tgcaggagga    960
 ggaggcctgg ctgcagcggt gcgcccagtg catcaacgac aagcttcagg gcctggggct   1020
 ggacgcaggc agcgaaggcg agccccccac gcgacaactg ctacaactcc tccagcctgc   1080
 ccgatgacat ctcactcttc acccatgaca acctgcacaa gcagcacagc tgcagcgact   1140
 ccctgggcaa gaagcagctg gacccgtcct gcatcaagct cattcgccac taagtgcacc   1200
 tgctctacct ctgcaccaaa aacaatcgcg tctggaccct tgagttcatg ggcaacctgc   1260
 actggaacag gaacagaggc gctcctacca gcagcagtgc aaggtccacg tgctggcccc   1320
 gagtgtaaag acatgaggag ctatgcaatc aatcctgaga ggttcagaga ggagtctgag   1380
 ggtcccccgc tgcccccgag aggagcagca aggacttctg caagatcccc ttggatgagg   1440
 tggtggtccc tcactgagct tcccggtgcg ctctccctac ctgctgtccg acaaggaggt   1500
 gtgcaagatc gtgcagcaga gcctctccgt gggcaacttt gccgcggggc tcctccaccg   1560
 ccgagaacct ccagctgcag tacaacaatt ttcgggcttg caacaagaag cagctggacc   1620
 ctacgcagct gcggctcatc tgccactagg tggaagccgt ctaccccgtg gagaaggtgg   1680
 aggaggtgtg gcactgcgaa tgtatcccca gcaacgacga gcagtgccac tgccctaaca   1740
 ggaaaaaatg caacatcctc aagaaagcca agaaagtgga gaagtgaagg cccgtggcct   1800
 gcccagagac tcggggtcac cagagactga                                    1830



      <210> 2217
      <211> 425
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(425)
      <223> n = a,t,c or g


      <400> 2217
 cggaattccn gntcgacgat ttcgtgagcc tgatgcccag atgctggaga tcccaaacct     60
 cacaccctac actcactaca gatttcgaat gaagcaagtg aacattgttg ggccgagccc    120
 ctacagtccg tcttcccggg tcatccagac cctgcaggcc ccacccgacg tggctccaac    180
 cagcgtcacg gtccgtactg ccagtgagac cagcctgcgg cttcgctggg tgcccctgcc    240
 ggattctcag tacaacggga accccgagtc cgtgggctac aggattaagt actggcgctc    300
 agacctccag tcctcagcag tggcccaagt cgtcagtgac cggctggaga gagaattcac    360
 catcgaggag ctggaggagt ggatggaata cgagctgcag atgcaggcct tcaacgccgt    420
 cgggg                                                                425



      <210> 2218
      <211> 825
      <212> DNA
      <213> Homo sapiens


      <400> 2218
 atgagggctc tcaaacttca gaggaggaaa tcgttttgga ttgtcgtggc ctgggaagct     60
 tttgtgcagc tggtaaatta tgaatgtaaa gtaggagaat ggaaaggcct agctcactgt    120
 gtttcacaaa acaataaata cagaaccaca tacatcatag caggggtccc caatccccag    180
 gaaccaggat acacagcagg aggccagtta aaaggaaatg atctgactgt tctgcatctg    240
 ctagtgattg aaggcaaatg ggaagcagtg cgcaagttcc cgttcaagaa atatatagtg    300
 aacacggcta ttgtgaagga ggcaaggaaa tactgggtag aagagggcag ttccctggca    360
 aaggccacac gctcaaaccc tggatacctg cagccctaca tgagaacagg cattcctgtt    420
 tttgcacccc caaagttgcc ttttggccca ccatgccctc tatcctgcac gcatataaac    480
 cccaaacccc aagctccaga agcagaccag cagctcccca tccatcttgc tgaaagccat    540
 ttccaccact caataaaacc tcgcatacat ccttcaagtc cgtgtgtgac ccgatttttc    600
 ctggatgctg aaagagagct cgggatacag aaagctgtcc cctggtcctt tacccttgtg    660
 aaaaagcaga agtcactggg acttccatca gtgcaagatt tcggcagtgt ctacaaaatg    720
 aacatttggt ctgatgtagc gtgctgtgac ccacagctgc aacaaccagc tgcgtctgct    780
 caaacttcag ccatcagcca gctcagtcgt gtaacggaat cttag                    825



      <210> 2219
      <211> 848
      <212> DNA
      <213> Homo sapiens


      <400> 2219
 catctagagg ctgggaatac ctaactttct gggaatgcag cccagcaagc ctcagcttca     60
 ttttcctagc cctcactcgg aatggagtcg ctctggttca aacgcctctg acaatatcac    120
 cccgttttat tttctatcac ttaccactat ctgaaattaa gtagataatt tgtttactct    180
 ctgtccccac ccactagaat gagaacgcgg cccttgcatc cttacgtgtg tctggcatat    240
 aaggggtgct caatgattat ttgtttcatg gatgaacaga tttatggatg gctgggtgga    300
 tgacgatctt agaaggggtt ccagggctag ctggctttct gtttctccca ctcaagcacc    360
 caagccctga cccacaaagt aaaggaacag gcgaaacttc tcgccaaata gcttcaaggc    420
 agaaactacg cagctggctt gggaattccg tacaacgcga acgcgcatgc acaggcagga    480
 ctgagcgtgt ccatcttcgc attactcccg gagatgactc tcggaaacgt tcatctgcat    540
 ctcattaccg ggtagcagga ataagtaggc tgaccctcag tttggaccgg gaacagctgt    600
 atctggagca gtccactgag ggacctgaac aagataaacg ggaagggaaa agcgccagaa    660
 gttcgagcag agaacccacc gggcagccgc ggacgttact gggaggaatg agggcgagga    720
 agagaaagac gttagtcctc ggaccgtttc cgagagtcat ctccgggagt aatgcgaaga    780
 tggacacgct cagtcctgcc tgtgcatgcg cgttcgcgtt gtacggaatt cccaagccag    840
 ctgcgtag                                                             848



      <210> 2220
      <211> 998
      <212> DNA
      <213> Homo sapiens


      <400> 2220
 acctgggcac cgtgtcctat ggcgccgaca cgatggatga gatccagagc catgtcaggg     60
 actcctactc acagatgcag tctcaagctg gtggaaacaa tactggttca actccactaa    120
 gaaaagccca atcttcagct cccaaagtta ggaaaagtgt cagtagtcga atccatgaag    180
 ccgtgaaagc catcgtgctg tgtcacaacg tgacccccgt gtatgagtct cgggccggcg    240
 ttactgagga gactgagttc gcagaggctg accaagactt cagtgatgag aatcgcacct    300
 accaggcttc cagcccggat gaggtcgctc tggtgcagtg gacagagagt gtgggcctca    360
 cgctggtcag cagggacctc acctccatgc agctgaagac ccccagtggc caggtcctca    420
 gcttctgcat tctgcagctg tttcccttca cctccgagag caagcggatg ggcgtcatcg    480
 tcagggatga atccacggca gaaatcacat tctacatgaa gggcgctgac gtggccatgt    540
 ctcctatcgt gcagtataat gactggctgg aagaggagtg cggaaacatg gctcgcgaag    600
 gactgcggac cctcgtggtt gcaaagaagg cgttgacaga ggagcagtac caggactttg    660
 aggtgagccg actcccaggc atcccatcct cctacgacgg tgccttcctt acgctgaaat    720
 tagttcttcc tgtctttgta tgaaattaga gctgggatcg ctatagtcta ggagtgaagg    780
 cagcttcgct cagcaggagc atggggggat cctgtctgca tttctgtttc caccatttct    840
 ccagcttgct ggggaaggag ggttacagaa gcaaagaagt gccagtttcc ttagaattgt    900
 gcttgataac tcctcaatga tcacacgcca gccgagctga gtacacataa gagtatgtgc    960
 acataggcgc ctccccctct gtccccagag cccatgcg                            998



      <210> 2221
      <211> 413
      <212> DNA
      <213> Homo sapiens


      <400> 2221
 tttcgtgaga acctaaaagc cttattcaga tcatcaagca gagcatcgtg gagctcaagc     60
 tgcaggcgga ggacagcttc gtgctgaagg tggtgcagct ggaggagctg ctgcaggtcc    120
 gccactccgt gttcatcgtc gggaatgcgg gcagcggcaa atctcaggtc ctcaccctgg    180
 ccagcaacga gcggatcccc ctgaaccgca ccatgaggct ggtgttcgaa atcagccacc    240
 tgaggacggc caccccagcc accgtttcca gagccggcat cctctacatc aacccagccg    300
 acctgggatg gaacccggtg gtgagcagct ggatcgagag gcgcaaggtg cagtcggaga    360
 aggccaacct gatgatcctc tttgacaagt acctgcccac gtgcctggac aag           413



      <210> 2222
      <211> 412
      <212> DNA
      <213> Homo sapiens


      <400> 2222
 aatacagctc gccgtctttt ccaaactcca ttaaaactgt tgcccagact gccatgaaaa     60
 cagcagagaa gacagtggct ccattgtcaa aaaggtgggt taccttggca tatacacagc    120
 tgtctgacag cctcatgaat ggacagtatt tatcacacac aggacacatg atgatatctg    180
 tagcttggca gacttcttta ctgacttggc tgtgatccac agtggtgacg ccatacaaaa    240
 agacaaacaa tccaatgaag gcagctggga aaagcatgcc ggtgtaccaa cccaaccaag    300
 caaaatataa cccaatcttc tctccaaagt accgccttac aagatccaaa ggttggtatt    360
 tataccacac gccccaggag gcccagcact catagagtag atgtcggtgg tt            412



      <210> 2223
      <211> 1836
      <212> DNA
      <213> Homo sapiens


      <400> 2223
 atggtggatt cgttaattgc gcgcgtagga gtaatggctc gcggtaatgc cattactttg     60
 cctgtatgtg gtcgggatgt gaagtttact cttgaagtgc tccggggtga tagtgttgag    120
 aagacctctc gggtatggtc aggtaatgaa cgtgaccagg agctgcttac tgaggacgca    180
 ctggatgatc tcatcccttc ttttctactg actggtcaac agacaccggc gttcggtcga    240
 agagtatctg gtgtcataga aattgccgat gggagtcgcc gtcgtaaagc tgctgcactt    300
 accgaaagtg attatcgtgt tctggttggc gagctggatg atgagcagat ggctgcatta    360
 tccagattgg gtaacgatta tcgcccaaca agtgcttatg aacgtggtca gcgttatgca    420
 agccgattgc agaatgaatt tgctggtaat atttctgcgc tggctgatgc ggaaaatatt    480
 tcacacagcg ataagttcga cgccaacgat ccgatcctga aagatcagac gcaagaatgg    540
 tccggttctg caacctttac atctgacgga aaaatccgtt tattctacac tgactattcc    600
 ggtaaacatt acggcaaaca aagcctgaca acagcgcagg taaatgtgtc aaaatctgat    660
 gacacactca aaatcaacgg agtggaagat cacaaaacga tttttgacgg agacggaaaa    720
 acatatcaga acgttcagca gtttatcgat gaaggcaatt atacatccgg cgacaaccat    780
 acgctgagag accctcacta cgttgaagac aaaggccata aataccttgt attcgaagcc    840
 aacacgggaa cagaaaacgg ataccaaggc gaagaatctt tatttaacaa agcgtactac    900
 ggcggcggca cgaacttctt ccgtaaagaa agccagaagc ttcagcagag cgctaaaaaa    960
 cgcgatgctg agttagcgaa cggcgccctc gtcaataccc agagcaccac caccaggagg   1020
 cctggaagca actcactgtc ccacttgatg tggcctgtgg accaccagaa atttcagagc   1080
 gtcacagaga tgtgtggttc gatcctgagc agggattttg ccgatttcgg aaccaccatc   1140
 aaacaggatt ttcgcctgct ggggcaaacc agcgtggacc gcttgctgca actctctcag   1200
 ggccaggcgg tgaagggcaa tcagctgttg cccgtctcac tggtgaaaag aaaaaccacc   1260
 ctggcgccca atacgcaaac cgcctctccc cgcgcgttgg ccgattcatt aatgcagctg   1320
 gcacgacagg tttcccgact ggaaagcggg caggattttg ccgatttcgg aaccaccatc   1380
 aaacaggatt ttcgcctgct ggggcaaacc agcgtggacc gcttgctgca actctctcag   1440
 ggccaggcgg tgaagggcaa tcagctgttg cccgtctcac tggtgaaaag aaaaaccacc   1500
 ctggcgccca atacgcaaac cgcctctccc cgcgcgttgg ccgattcatt aatgcagctg   1560
 gcacgacagg tttcccgact ggaaagcggg caggattttg ccgatttcgg aaccaccatc   1620
 aaacaggatt ttcgcctgct ggggcaaacc agcgtggacc gcttgctgca actctctcag   1680
 ggccaggcgg tgaagggcaa tcagctgttg cccgtctcac tggtgaaaag aaaaaccacc   1740
 ctggcgccca atacgcaaac cgcctctccc cgcgcgttgg ccgattcatt aatgcagctg   1800
 gcacgacagg tttcccgact ggaaagcggg cagtga                             1836



      <210> 2224
      <211> 309
      <212> DNA
      <213> Homo sapiens


      <400> 2224
 atggggaagg ccatgttgca gctgctgatc agagcacatt ggacggtgtt tccgtgtgaa     60
 catgaagaca atgctgcctc tgtttctgtg acgctgtgct ctgatcttgc tggaggcgaa    120
 gtggtgtcag ctgtgcttac aggacagtca gtggtgcaaa ctgagaaaga gatcgatagg    180
 tcatcaaagc cacctgcttg cttggtggcc cctcaagttg tcttctgctc agaagttctg    240
 agagttgatg aaagttatca tcgaaagtac ccagtccagc tcaggccagt ccatattgct    300
 gccaagtaa                                                            309



      <210> 2225
      <211> 463
      <212> DNA
      <213> Homo sapiens


      <400> 2225
 aaggggaaaa aaatcggtga ccacggtggc tggccccatg gcccaggacg tggagagcct     60
 ggcgctgtgc ctgcaagccc tgctgagtga agacatgtac cgactggacc ccactgtgct    120
 ccagatgccc tttagggagg aggtgaagac cccctttccc accccaggct gcagtgagtg    180
 agaagcccac atgctcagtc cagtttgttt ccttcccctg ctggacacca gctgctttgg    240
 cttcttggct atctggagcc atagcttgta agtgccccca aagagggcct ccagtgccat    300
 atacccaacc catgcagtta gaatactcag caagtgtggt tgagagggtg tggcatccag    360
 ttaagctggg tttttaaccc tctaggtaac cctggccaag tcacatctct tctttcagcc    420
 ttagcctccc catcaataca ataaagaggt taggctggga gat                      463



      <210> 2226
      <211> 390
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(390)
      <223> n = a,t,c or g


      <400> 2226
 acgcccacgc gtacgagatc gggaatttct tttatgaaga ggaggcggca gctcagggcg     60
 agggtgtttg ccctggccct ggcgtggagc ctgggcccgt gctgggctct gagggttgct    120
 gtcccgaagg cttcanccac catccggggg ccacagcgga ggctgctagc gagcctgctg    180
 caggaaaata ctgagatcct cggctacctg ctgggtagcg ttgctgcctt tggctcctgg    240
 gcttctcgga tcccccctct ctccagaatt tgccggggga agacatttcc ctccatccac    300
 ctgtggaccc ggctcctgtc ggccctggct ggcctcctct atgcctcggc cattgcggcc    360
 cacgaccggc accctgagta cctgctgcgg                                     390



      <210> 2227
      <211> 566
      <212> DNA
      <213> Homo sapiens


      <400> 2227
 taatggtgcc atccgacagc agagcactgc agtacacttc atacatattt gtaggaaaat     60
 gcttttgtaa ttgtttgaac tagagtcttg actagaattt agtatgagtg acaatgtgga    120
 gccatctatg attaatccat attcctgatg ttctgtccat gcttttttaa agcttctagt    180
 acttttagga aactcatgca gcaatttctt gcgatattct atcaataatt catgtaatcg    240
 atcttctttc ctttcacttt cttcaatggt ttttgtggtt agttctaaga gctcagtgtt    300
 ggtctggaaa aggcggcagg catagcatgt ggatttagct gtctccatct tgtccccagt    360
 gagcacccag actttcaggc ctgctgcatg cagagcttca atggtctctg cagcttgatc    420
 ttgtagcttg tcttcaactg cagtggctcc aattaaattc atgtttgtct caatatcatc    480
 gaaaactttt tccatttttt cttctctgtc ttgtaaggcc atttttgcct ctatgagctg    540
 tctgttaatt ctttcataat acgaaa                                         566



      <210> 2228
      <211> 394
      <212> DNA
      <213> Homo sapiens


      <400> 2228
 tttcgtcgcg gtgggctttt caagtgctca gtccctctgc ggacagtgcg aggctgccgg     60
 gccgggctcc gggggaccga gactgtacct tccagccttc agcgccagca ccttccaaac    120
 ctttccttct gagcaccccg ccattctact cggcgtgctg cggagggtcc tgtcggcgcc    180
 ctgcatcctc cactgctttt ccaagagaag agagcatgct gcctctcctg acacaggact    240
 ctaattccaa agctcggagg ggcattttaa gaagagctgt cttttctgag gaccagagaa    300
 aggctctgga gaaaatgttt cacaaacaga aatatatcag caaaacagac cgaaagaaac    360
 ttgccatcaa cttgggacta aaggaatcac aggg                                394



      <210> 2229
      <211> 406
      <212> DNA
      <213> Homo sapiens


      <400> 2229
 tttcgtcggg gagcagcccc gcgcgggagg aggaggacta ggagcccgga gacccccggg     60
 agggggagga agaggaggag gaagacgagc cggaccccga ggccccggaa aacggctccc    120
 tgccccgatt cgtgccgcgc ttcaacttca gcctgaagga cctgacccgc ttcgtggatt    180
 tcaacatcaa agggcgcgac gtgatcgtgt tcctccacat ccagaagacg gggggcaccg    240
 ctttcggccg gcacctggtg aagaacatcc ggctggagca gccttgtagc tgcaaagcgg    300
 gtcagaagaa gtgcacctgc caccggcctg gcaagaagga gacgtggctc ttctcccgct    360
 tctccaccgg ctggagctgc gggctgcacg ccgactggac ggagca                   406



      <210> 2230
      <211> 954
      <212> DNA
      <213> Homo sapiens


      <400> 2230
 tcaggttagc tgcagctctg ttccatgtgg cttcttcgca gttgggtcca ggctgaagga     60
 gcagtctcta tttcggacag ccccttctcc ctgcatcagt gctgggccgt gctgcacaaa    120
 gcctggtgtg ttttcctcca gcttccaggt ggcttcactt ttactctcaa tcctctttct    180
 gacaatctgc ttggtaaacg tgtggactcg gccccttcct ggggccctct tggctctgcc    240
 ttcagaggtg tccacatgcc ctgtgttggt gctgcttggg aaggcaaagg ccccaatctg    300
 ctcagaccaa gtggtaagct tggaccaagc ggatccagac caactcccat aggtcagcag    360
 caacttcctg aagtcccgcg tgcaaaggga cctttgggcc cagcagctgt gatctgtcag    420
 caatgcctgc tccaagcacg ggagggaaaa gaggcagttt ttccggcagg tacttgtcag    480
 cttctctgga gctaggcgga ctccccatgg ctcccaccgg cccctctgct ctttctgctc    540
 caccctccgt gtccagggga gcccgataga gcacgcggga aaagccgggt gtctacgctt    600
 ccgcgactta ggctgcagag ataagagaag gtcaggctct gggaggacgc gaggccgtcc    660
 aggaatggca gggaggcccg ctggggcctg actttggtcc taatggacca aagcttcgac    720
 ggagcaaggc cgggtgtccg tggtggcacc tctcatcagt ggacgctggc gaatgactat    780
 ggaaacaaca ttcaacagca gtgttttcta tgccaggtac acaaccgcct tggcgtgggt    840
 tgataaccat gcctatctca ccgcgtggca ctgagccgac cgcacaccca gggccccggt    900
 ctccagggct cgcttactcg cttactgcgt gaagcatcac gaaatcgtcg accg          954



      <210> 2231
      <211> 416
      <212> DNA
      <213> Homo sapiens


      <400> 2231
 aaccggctga ccacacacag tcctcactct cctggccctg gtgggcggca ggcaccatgg     60
 cgcagacagt gccgccctgc gagctgccct gcaaagagta cgacgtggcc cgtaacacgg    120
 gcgcctacac gtcctccggc ctggccaccg ccagcttccg cacctccaag tacctgctgg    180
 aggagtggtt ccagaactgc tatgctcgct accaccaggc cttcgccgac cgcgaccagt    240
 cggagcggca gcggcacgag agccagcagc tggccacaga gacccaggcg ctggcgcagc    300
 gcacgcagca agactccacg cgcacagtgg gcgagcgact gcaggacacg cacagctgga    360
 agtcggagct gcagcgtgag atggaggcgc tggctgcgga gaccaacttg ctcctg        416



      <210> 2232
      <211> 1359
      <212> DNA
      <213> Homo sapiens


      <400> 2232
 atgcccccgc gcgcgccgcc ggcctcagtt tcccgggggc ggatgggcgg gcgggcgcgg     60
 cggcggcggc gggagatgtt cgcggtacgc ggccccggac ccgtggggga cgtcgagggg    120
 tctcggggcg ccgcgctcag ctccccggcc ccgcggccct ggacaccgct ccaggaccct    180
 ggcggctggg accccaggaa gaaaaccgtc taccggagtc tgtgcctggc cctggccctg    240
 ctcgtggccg tgacggtgtt ccaacgcagt ctcacccctg gtcagtttct gcaggagcct    300
 ccgccaccca ccctggagcc acagaaggcc cagaagccaa atggacagct ggtgaacccc    360
 aacaacttct ggaagaaccc gaaagatgtg gcccaggcct gggacgtgac caccactaac    420
 tgctcagcca atatcaactt gacccaccag ccctggttcc aggtcctgga gccgcagttc    480
 cggcagtttc tcttctaccg ccactgccgc tacttcccca tgctgctgaa ccacccggag    540
 aagtgcaggg gcgatgtcta cctgctggtg gttgtcaagt cggtcatcac gcagcacgac    600
 cgccgcgagg ccatccgcca gacctgggcg cgagcggcag tccgcgggtg ggggccgagc    660
 gccgtgcgca ccctcttcct gctgggcacg gcctccaagc aggaggagcg cacgcactac    720
 cagcagctgc tggcctacga agacgccctc tacggcgaca tcctgcagtg gggctttctc    780
 gacaccttct tcaacctgac cctcaaggag atccacttcc tcaagtggct ggacatctac    840
 tgcccccacg tccccttcat tttcaaaggc gacgatgacg tcttcgtcaa ccccaccaac    900
 ctgctagaat ttctggctga ccggcagcca caggaaaacc tgttcgtggg cgatgtcctg    960
 cagcacgctc ggcccattcg caggaaagac aacaaatact acatcccggg ggccctgtac   1020
 ggcaaggcca gctatccgcc gtatgcaggc ggcggtggct tcctcatggc cggcagcctg   1080
 gcccggcgcc tgcaccatgc ctgcgacacc ctggagctct acccgatcga cgacgtcttt   1140
 ctgggcatgt gcctggaggt gctgggcgtg cagcccacgg cccacgaggg cttcaagact   1200
 ttcggcatct cccggaaccg caacagccgc atgaacaagg agccgtgctt tttccgcgcc   1260
 atgctcgtgg tgcacaagct gctgccccct gagctgctcg ccatgtgggg gctggtgcac   1320
 agcaatctca cctgctcccg caagctccag gtgctctga                          1359



      <210> 2233
      <211> 3123
      <212> DNA
      <213> Homo sapiens


      <400> 2233
 gtcaggtcca tgagctgccc accgtcctgg ccttactgtg ccccctgccc caccaacata     60
 ggtgaaagca cctcccctct aaggaagacc atagagaccc caacactgtg ggaccccaaa    120
 gctccttcat gctcactgga gctcccaccg tgggtgcttg caagtcctca gcgctcccgg    180
 ggtacagccc tccccttcct gccctctaat gtcctcccct cccttgccct tccctccact    240
 tcctttctct gccgtcccct cctctcccat cttgtgacct ctttactggc ggggcctgga    300
 gcccatgatg gacacttgcg gaaggagggg tggcggagca cccctgagat gacatcgctg    360
 cctgccccag agcaccccgc ctctccctgt gactcagttc tttgcagccc agatgtgagc    420
 atgtgcaccc tgggacctgc tgcccgttgg gatgcccagg ccaaatcagc ccctctgcct    480
 ccatgctgca ctgattgcaa gagtttccca catctgcaga ggccgtgggc tcagccccac    540
 accagccagg ccaccagtgt tgatagcggt gaggcgggga caaagggaat gtctcagttc    600
 acagtgtgga catggtggag gtctcggcct tgcgagacaa ggcaggggga ggggatagga    660
 aattgggggt attctgtgac tcctgggcca ccggggagcc agaatcttcc agccagactg    720
 gatgggcagg gcttagcttc ctgatgccgc ccattcacca ctttcacccc gggaacctac    780
 ctgggcatca tgggaggcag agcctgaacc ccaacccaac cctaactcta atgctaaccc    840
 ctaaaccatc cctcacccta acccaatcct cgccctaacc ctaatgctaa cccctgaccc    900
 gacccaatcc taaccctgat gctaacccct gactcaactc tcaccctaac cctgatgcta    960
 acccctgacc caatcctcac cctaacactg atactaaccc ttaacctaac ccaacccagc   1020
 cctaactcca actctaaagc taactcctaa ccctaggaga ggagcccagg ccgggccctc   1080
 tccctgctgg tttcctgttg ggctttggag ccccagatgc ctgcccagag gcttccttgt   1140
 gcggggtggg gtccagcagt gggggatggg cccagagctg gtgtagccac cagcagagcc   1200
 atcctgatcc acaggaccat ccctggtggg gtggggcccc ctggggcagg aaggccactg   1260
 aggccaggga gactcccagg cccactcacg gcgcaggccc cacaggagct ggctggaggc   1320
 tatgggtgcg gggcgtgggc ctgccggggg ttgcgtgaca ggcagtgggg agtgggttgt   1380
 gctggcagct gtgggtgagt gaggaggctc ctctcatgaa gggccctggg gaagtggaat   1440
 ctggccctga gagacccccg gcctcctctg caggggctgc cggcaggagg ggaaccgggg   1500
 accacctccc gccacagagc ctggggcccc cagccttgcc tacagggagg gtagatgaga   1560
 gtgtaaactg catatgaggt tgggctaaac ctggacatgt gtttcataac caaagcagcc   1620
 aggaatctcc ggctctgccc agtgatcatc tgggcaggac atggggacga gtgtccaggc   1680
 tgaagtcagg gcccggccag cagagggcca ttttgtattg agctccacag ctggtcacat   1740
 tctgtggaat gtgcagacgt gcacggccca tcagacaggg tctggagtgg ggctgccatc   1800
 ttgggcagct cctcccgggt gtctgcaaaa tgcagaggtc accagagcca aggcagcaag   1860
 gcaaggagcc cggcttctaa ggaactctga gcaggtgtgg tccatggctg ggaggcagct   1920
 ggccccacag cacatagcac ggagggcggc gcggagtcct ggacgctctt ggcaggtccc   1980
 ctcatggagg atgtggggga ttggcttagg cctggtctgg ctggccttcc tggaccgcag   2040
 tggccaggag ctgaaaaccg tgaccccagt ctccctgcag ctgttcttga tgggatttct   2100
 gttcgccagt cagatgcatt tgcacaggac ttggatcctg aactgtgtaa cctggagagg   2160
 caggtgtgag cgggccatgc tgctggccca gcctgtgccg gtgtctgttt ctgttgtctc   2220
 tcggcccttc tgtgagccct cagtaaagct cttcgtgctt cagtcagcaa gagtggattc   2280
 tgtcgtcggc aactctgggg accaaacccc gagcctcccc ctcccccaga ccttgcagtg   2340
 ccatggagct gagggacctg tggatccaca gctgtggccc cggaagggct gcaggagctg   2400
 aacctgcgtg agccccgcag agggtgcaga gccggcttgt gcaggctccc agcaggctca   2460
 tgacagcgcg gatggttaaa tgtagctcct gacagccaac tgttaaggtt tcaggcattt   2520
 ttgcaccagg tgacatgatg gtagcctgaa cgtgaccttg gcagcagtct ctacatcaag   2580
 gaaactggca aatgtcaaca tgctgggtac cctcgctcct gccgccgcag gctgtcagtg   2640
 tcttccagcc cacactgcgg ggggccttgt tgtgtggctg cctcccaggc tggggcgagg   2700
 gtctccagag accaccatcg tgcaggctct tggtcaatag cagggtgtgg tgctcctgcc   2760
 aggggacgca ttctccgtgt gacctctaca ccccaggtca ggtcaggatg tgatttgctt   2820
 ctccagggcc gtgactcact agatccacct cccactggtg cctggtggcc cccgacagcc   2880
 ctggccctgt ccaggccctg gcctgtccta cagtcacagg tgctggcctg tccctgctgt   2940
 cctcctgacc acctggtgct cccggccacc ctgcccgccc ccctgtctcc tcgggacagc   3000
 ctggctgcct ccacttgctg gcccctgccg gcccaccctc tttccaagcc tgccctgccc   3060
 ctcagctcct ggggtgggga ggggagacct cgccttctgc ctgcagcgac tcccacctgt   3120
 cac                                                                 3123



      <210> 2234
      <211> 799
      <212> DNA
      <213> Homo sapiens


      <400> 2234
 ggcacgagaa ggaacaggga ttgctcactc ggggagctcg gctcttgaga caggaatctt     60
 gcccattccc cgaacgaata aaccccttcc ttaactcagc gtctgaggaa ttttgtctgc    120
 ggctcctcct gctacattct gagtggggaa agggactaag gtggtctgag gaccccacag    180
 agtcaggaag attgagagag tgcccctccg gcctcgccat gaggctcttc ctgtcgctcc    240
 cggtcctggt ggtggttctg tcgatcgtct tggaaggccc agccccagcc caggggaccc    300
 cagacgtctc cagtgccttg gataagctga aggagtttgg aaacacactg gacggacaag    360
 gctcgggaac tcatcagccg catcaaacag agtgaacttt ctgcccaaga tgcgggtgcc    420
 cctccggcct cgccatgagg ctcttcctgt cgctcccggt cctggtggtg gttctgtcga    480
 tcgtcttgga aggcccagcc ccagcctagg gggctccaga agtctccaac ccctttgatg    540
 gcctggagga gttaggaaag accctggagg actacactcg ggaattcatc aaccgcatca    600
 cacagagtga acttcctgcc aagatgtggg attggttttc agagacattt cggaaagtga    660
 aggagaaact caagactgac tcatgaggac ctgaagggtg acatcccagg aggggcctct    720
 gaaatttcca acaccccagc gcctgtactg aggacgccct ccatgtgtgt ccaatgtggt    780
 cacacgccca ggtgtgacc                                                 799



      <210> 2235
      <211> 5195
      <212> DNA
      <213> Homo sapiens


      <400> 2235
 gcctcgcggg cctcggcccg gtgcgagcgg ctccgcgatg tggctgagcc cggaggaggt     60
 gctggtggcc aatgcgctgt gggtgacgga gcgggccaac cccttcttcg tgctgcggcg    120
 acgccggggc cacggcaggg gcggcggcct tacgggtctt ctcgtgggca ccctggacgt    180
 ggtgctggac tccagtgccc gcgtggcccc ttaccgcatc ctgcaccaga cccaggactc    240
 ccaggtctac tggacagtgg cgtgtggttc ttcccgcaaa gagatcacaa aacactggga    300
 atggctggaa aataacttgc tccagacact gtccatcttc gacagtgagg aagatatcac    360
 caccttcgtc aagggcaaga tacacggaat catcgcagaa gagaacaaga acctgcagcc    420
 ccagggagac gaggaccccg ggaagttcaa ggaggctgag ctgaagatgc ggaagcagtt    480
 tgggatgcct gagggcgaga agctggtgaa ttactactcc tgcagctact ggaagggccg    540
 cgtgccccgg cagggctggc tgtacctgac ggtcaaccac ctgtgcttct actccttcct    600
 gctggggaag gaagtgagcc tcgtggtgca gtgggtggac ataacgcgtc tggagaagaa    660
 cgccaccctg ctcttccccg agagcatccg tgtggacacc cgcgaccagg agctcttctt    720
 ctccatgttc ctcaacatcg gcgagacctt caagctcatg gagcagttgg ccaacctggc    780
 catgcggcag ctgctggaca gcgagggctt cctggaggac aaggccctgc ctaggcccat    840
 ccggccacac aggaacatct cagccctgaa gcgagacctg gacgcccgag ccaagaatga    900
 gtgctaccga gccacgttcc ggctgcccag ggatgagcgg ctagacggcc acacaagctg    960
 caccctgtgg acgccgttca acaagctgca catccctggc cagatgttca tctccaacaa   1020
 ctacatctgc ttcgccagca aggaggagga cgcttgccac ctcatcatac ccctgaggga   1080
 ggtgaccatt gtcgaaaaag ctgacagctc cagcgtgctg cccagccccc tgtccatcag   1140
 caccaaaagc aaaatgacat tcctgtttgc caacctgaaa gaccgtgatt tcttggtgca   1200
 gaggatctct gacttcctcc agaaaacacc atccaagcag ccaggcagta tcgggagcag   1260
 gaaagccagt gttgtggacc ctagcacaga gtcttcccca gctcctcagg aggggtcgga   1320
 gcagcccgcc agcccagcct ctcccctcag cagccgccag agcttctgtg cgcaggaggc   1380
 gccaaccgca tcccagggcc tgctgaagct cttccagaaa aactcgccca tggaggacct   1440
 tggagccaag ggggccaagg agaagatgaa agaggagtca tggcacatcc acttcttcga   1500
 gtacgggcgt ggcgtgtgca tgtaccgcac agccaagacg cgggcactgg tcctgaaggg   1560
 tatccctgag agcctccggg gagagctgtg gctcctcttc tccggggcct ggaatgagat   1620
 ggtgactcac cccgggtact atgctgagct ggtggagaag tccaccggga agtacagcct   1680
 ggccacagag gagatcgagc gagacctgca ccgctccatg cccgagcacc ctgccttcca   1740
 gaacgagctg gggattgctg ccctccggcg ggtgctgact gcctatgcct tccgaaaccc   1800
 caccatcggc tactgccagg caatgaacat cgtgacctcg gtgctcctgc tctatggcag   1860
 tgaggaggag gccttctggc tcctggtggc cctgtgcgag cgcatgctgc ccgactacta   1920
 caacaccagg gtggtgggag ccctggtgga ccaaggcatc ttcgaagagc tcacgagaga   1980
 cttcctgccg cagctctcgg agaagatgca ggacctgggg gtgatctcca gcatctcgct   2040
 gtcctggttc ctgaccctct tcctcagcgt catgcccttc gagagcgccg tggtcatcgt   2100
 cgactgcttt ttctatgagg gcatcaaggt gatcctgcag gtggccctgg ccgtcctgga   2160
 cgccaacatg gagcacctgc tgggctgcag cgacgagggc gaggccatga ccatgctggg   2220
 cagatacctg gataatgtgg tcaacaagca gagtgtctct cctcctatcc cgcacctccg   2280
 tgccttgctg agcagcagcg atgacccccc tgcagaggtg gacatctttg agctcctgaa   2340
 agtgtcctat gagaaattca gcagcctgag ggccgaagac attgagcaga tgcggtttaa   2400
 acagaggctg aaagtgatcc agtccttgga ggacacggcc aagaggagtg tggtccgagc   2460
 tatacctgtg gacattggtt tctccattga agagctggag gacctttaca tggtgtttaa   2520
 ggccaagcac ctggctagcc agtactgggg gtgcagccgc acaatggccg gccgtcggga   2580
 ccccagcctg ccctacctgg agcagtaccg gattgatgcc agccagttcc gggaactctt   2640
 tgccagcctg acaccctggg cctgtggctc ccacacacct ctgctggcag ggcgcatgtt   2700
 caggctcctg gacgaaaaca aggactcgct gatcaacttc aaggagttcg tgacagggat   2760
 gagcgggatg taccacgggg acctgacaga gaagctcaag gtgctctaca agctacacct   2820
 tcccccagct ctgagcccag agggaagccg agttcagccc tggaggcgac ccatttattt   2880
 tcacagaggg acagctcctc agaagcatct cctctggcct cagatctgga tcttttcctg   2940
 ccctgggagg ctcaagaagc actaccacag gaagagcaag aaggaagtgg aagtgaggag   3000
 agaggagagg agaaggggac cagctctccg gactatcggc actaccttcg aatgtgggcc   3060
 aaggagaaag aggctcagaa ggagacgatt aaggatcttc ccaagatgaa ccaggagcag   3120
 ttcattgagc tgtgcaagac gctttacaac atgttcagtg aagaccccat ggagcaggac   3180
 ctgtaccacg ccatcgccac cgtggccagc ctcctgctcc gcatcggaga ggtggggaag   3240
 aagttctcag cccgcacagg caggaagccc agggactgtg ccactgagga ggacgagcca   3300
 ccagcacccg aactgcatca ggacgcagcc agggagcttc agcccccagc tgcaggagac   3360
 ccccaagcca aagcaggcgg agacacacac ctcggaaaag ccccacagga gagccaggtg   3420
 gtggtggagg ggggcagcgg cgagggacag ggctcaccct cccagctgct gtctgacgat   3480
 gaaaccaaag acgacatgtc catgtcctcc tactcggtgg tcagcacggg ctccctgcaa   3540
 tgtgaagacc ttgcagacga cacggtgctg gtgggcgggg aggcctgcag ccccacagcg   3600
 cgcatcggcg gcaccgtcga caccgactgg tgcatctcct ttgagcagat cctggcctcc   3660
 atcctgacgg agtccgtgct ggtgaacttc tttgagaaga gagtggacat tggactcaag   3720
 atcaaggacc aaaagaaagt ggagagacag ttcagcaccg ccagtgacca tgagcagcct   3780
 ggagtttccg gctgatgcct gcagctgtga ggcctggccc aaggtgtcat cagtggggct   3840
 ggcctcatct cctcctgcct ttcctccctt atcagtttct ctttaaaggt gtgcccctcc   3900
 tgctctccca ggagcagtga gttgtgagtg gaaagaaggc tggtgcagac ccagctgcct   3960
 tagacagatt ccctgggcct gcatctcctg gcgccggctg cttctgggcc caggaagagg   4020
 ctgtggctcc caccttcctt acacctggtg ggagcccgcc tcgcaccagc tgcacctgcc   4080
 tagcattaga ggctctcaga tctgcccttg cttgcctcat acctctgtgc tccacactgc   4140
 ggccaggcca gctgagtccc tccatccgtg gatgctttcc tgcagctatg tggtatgggg   4200
 gtcattcctg cctcttggca ccaggttggg gggcatgtgc ttgttgggca ccaaagtgat   4260
 ggaaccctca ggtgctctcc gggagcctga acctcctgac tgaggaacat gggcagaaca   4320
 tgtttattgc acagagtggg cgctgcgcac aggcgtggct gtacacgtgc tctcagctca   4380
 tcatcctttc cagtaacttt aaaaaaacat ccctcaggtc ctgatatatt tccttggatt   4440
 catttcactt ggctagaaat tacactgtgc tcaatgcctt aataaatccc tgaaagaaat   4500
 aaaaaccact gtgtgcaatg ccttgctgtg gcccccaacc actgcttagg cctcccaact   4560
 tctccccagg ccaagtatgg ggccctggct gtgttctgga agttcaagac acttagtcct   4620
 ccacagtggg tggaagagtg caaggtctgc caggtcagat ggagacggca gaaccttgct   4680
 ggtgcaagct gggcaggtcc tgaccaacct gcatcagggg atgcccctga gcttccacag   4740
 gtctttcatg gggcaggggt tgtgggtcct ggtgaaggaa gtgcatccct caggcccctg   4800
 ggctgtagca aagctgtctg ccccctgggg gttcaaagaa cccagactgt ggagccaaag   4860
 gtgaccgcag ggggccccag ggctggagcc acaaggatac cctcactttg catgaggagc   4920
 tgaaactgac cagtgtccag tgttagcccc cacatggggc tgctcttgct tctactaaaa   4980
 gatacagcag ttaccccctt atccacaggg gatacagtgg atatctaaaa ccagaccccc   5040
 agtggatgtc taaaaccaca gataataaca aaccttatac atactgtttt ttcctatgca   5100
 tacatacctg tgattaagtt tatgaattag gcaccttaag agattgacaa caataactaa   5160
 taataaaatg taacggttat actgtaaaaa aaaaa                              5195



      <210> 2236
      <211> 682
      <212> DNA
      <213> Homo sapiens


      <400> 2236
 gttggagacc ctggctgggc ccctggccca gtgcccgccg cctgcccctc ccgctgagaa     60
 caggatgtgg gtgtcaggag ccccagcggc cttcccagct tcccctgatt gtgtacaggg    120
 cgataaaggg gctgatgaga gggagatctc tggcggcaca gacacagcgg cggcggctca    180
 actgaagatt cactattgga taccagggcc tagcacggtg caggagcaca aggaagtgtt    240
 caacaccaag ctggctgatg gacaaaatgg atcacccagc aaacaagcaa gtatctgtga    300
 caggcagttt gttgtggcag gagggtacca tcgctcattg gcagatgagg cttatggaga    360
 tgaggaggac ttgcccaagg tcgtgggcct ggtgcacagc accagagggc cagcccatcc    420
 cacttacctg ctcaggcctc tgcagaagga ccaggactca agtctgctga gagcgtctgg    480
 aggaggaggt ggcagcccca gcagtagtac gaaatcagaa cacagctgcc gacagataca    540
 cattccaggc cccttcagcc atgctgatat tacagggcag aagtggtttc caggcggcgt    600
 gtccacagag cctgccagga acatggggtt cctgaagcct accccaacac ctctgctacg    660
 ctcacccaag gactttcggt ga                                             682



      <210> 2237
      <211> 3097
      <212> DNA
      <213> Homo sapiens


      <400> 2237
 atggcgggcg cgcgggtggg tcccgccgcc ggagcgcgca cggcagtgcc cgccgcgggg     60
 ggtgggggcg cggctacaca ctcgcgggtc agatcccgga cggccaccca gggacgcaca    120
 gctgatcgcg gctgcacacg gcgcgtgcac acacacgttc actcacctca aatggagccg    180
 gccacccaca ttgttgtaca cccagccaca cacattcgca gcgacactca acatagcgct    240
 ccacacagca aaagtgtacc ccgctgctgg aacgactgcg gatagcccct aaagcctcag    300
 gcagtgacat tgggtgtctc accccgcaga gctacccaca ctcagcaagg gcaagcccgc    360
 gtgtgtgcaa acacgcgctc ccgtttaccc acagaagtgc ctgcctctcc agcgctcaca    420
 gacacacaaa aagggacagg aattggtcac tgggtagtgg ccgtggctcc gacgatccag    480
 accagcgtct ggcccaagcc attcagagga aataggattt ctgtactggg atttgaaccc    540
 cattcccttg tttctgctga cccccagcag tctcaatatc cctacttcct cttcccagaa    600
 ccaccctccc caaagccctt atcgatgctg gaggattcct atgcatccct caaaatccaa    660
 gcttcggcga gagcaccacc gttgtcgccc atcgacatgg acaagcagga gcgcatcaag    720
 gcggagcgca agcggctgcg caaccgcatc gcagcatcac aagtgccgca agcgcaagct    780
 ggagcgcatc tcgcgcctgg aaagaaagtg aagaccctca agagtcagaa cacggagctg    840
 gcgtccacgg cagcctgctg cgcgagcagc tcctcccttg ttggagggag cagagagcgg    900
 gtgtctgaga gcggcccgca catctgcgcg cagcgagcgc cccctagacg cgccttggcg    960
 cggggccggc tgatgccagg tgacactggg ccccgtgagt tacacaggaa cccgagtgtg   1020
 gtggtggtcg tgtgtttgct ggtgtctctt ttgctcatcg ggtctgtggt catggctgtg   1080
 agattctgtc accggaatga gtccaagttt gagaacctgg acgaggtgtc catgggatcc   1140
 gtgaatgaca gattgtcctt tgcccaccac ctccaggaac accagttcct cttcccccga   1200
 gtcgctgggt gcagagccag aggaacgcca gcgaccccag cagcgctcgg acggtgctgg   1260
 ccgtggccgc tgcggccccc gtgtccaggt gggccagacg cagcctctgg gcgccgtcgc   1320
 ttttccagca tcgcagaggc aaaaggtggc agtgggaccc aaaaggatgg gcccaagccc   1380
 gtttaggctt gcagccacgg tacggcagcc ggagcgcccc caagccccaa tggccgtgcc   1440
 atcctgcccc tccactcccg actatgagaa catgtttgtg gccagccagc agccgagcac   1500
 cagtgggatg aacaagggta aggccctacc tgccggcatc ctgcagatgg tcaccgacac   1560
 atccaggccc aacgtgggcg gggatgagtc tctggactgt ttggtactca accgaatctc   1620
 gtacacatgc aggtccacgc tgtcgccaag gcctagcttt tcagctcctg gaagagagga   1680
 gagtgggagt gtcatggccc cagatgacag catggggata atgcgctctc tggggggtct   1740
 gtctagactc actgtggcag caattgtccg tgatgttacc aagttctgtg acccgggtcc   1800
 tcctcaccca gctttgcaag agacacccca gatggccccg agccccggag ctccccagcc   1860
 cttaaaccca cctgcacctc ctcggaagag aaacacagcc agtgccccag tccacctgag   1920
 agctgcgaga gatgacagcg aggctgcact gtaccccttc ctacaagttt cctattcgtt   1980
 aagtgggcac aagaataact acacgtacta tgcatgggtt gttgggggat tcagagcgct   2040
 ggggtacaaa cactcaacag atgtgtgctc cggtgttacc atccaggaag agatgtggat   2100
 ccgacatcgt tttttaagag ctgcccccat cagccagcgt acccgtcact accaccgctt   2160
 cctcggctgc tccatggcgg gatcgggctg tgcctcggac ctgctttgtt gcgactggcg   2220
 cgacagctgc tgccgctgca gcctctcggc cgcgcaggcc acgcccctgt caagcccccg   2280
 gcctcgcccc cggtcagccg ctcgccttag tgcgcgcggc gcggcgacga ccgccgggag   2340
 cgtgtgcagc ggcggcggcg aagtggccgg cgagcccggt ccccgccggc accatgttgg   2400
 tggagctgaa aaatggggag acgtacaatg gacacctggt gactgcgaca actggatgaa   2460
 cattaacctg cgagaagtca tctgcacgtc cgggacggga caagttctgg cggatgcccg   2520
 agtgctacat ccgcggcagc accatcaata cctgcgcatc cccgacgaga tcatcgacat   2580
 ggtcaaggag gaggtggggc caagggccgc ggccgcggag gcctgcagca gcagaagcag   2640
 cagaaagccg cggcatgggc ggcgctggcc gaggtgcttc ggggctctgt catgctgtgg   2700
 cggccgcgag agcgactcaa cctgctgcaa gcctctgccc ttcgccgacc cccaggttct   2760
 ccatgcgcca gagaaagggg tctgggaagc agggagcagg actcgtcccc gtgagcgggc   2820
 gccgaggagc gtctgccccg ggtccggccc agggccggga gtggaggcga cagcgaggag   2880
 ctgtcgcgcc ggaggtgctg aagcggtaga aggtggaact ggggctcaag cctcaatggt   2940
 gaacaccact gggtactggg ctcgacctct ccaggcaaca caaggcggct cggcagcgtg   3000
 gcagcaatgg ggtacccgag aagcctctcc ggatgatacc accaccaggg ggctcacagg   3060
 ggccaagcca gaatccacca actcccagaa ccactga                            3097



      <210> 2238
      <211> 1627
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1627)
      <223> n = a,t,c or g


      <400> 2238
 atttgagacc tttctgagac catagtcagt gtggtggaat tcggcatttt gtcgtgggca     60
 ggggctcagc tgtcggttcc atagaggacc ttccagataa ggaggcccct ccagcccctg    120
 actgccgagc ttgatttcca ggaagggttg tggaagtcac cgagtgccct ccatgcacct    180
 gtgaagagtg cccagtgggg ccctccctgg agtggagagg agtgactccc cgtggccagc    240
 agccttgcct tcctggggca caccccgcat acagcttctc cccgggctgg gacagtggaa    300
 gggctgcctt gccatcacct ccctgcgcac ttgctttgcc caggtcctgg ggctctgctc    360
 ctgccagctc ctgggtggtt catgctcctg tgagggcact gaccagccaa gcaggaggcc    420
 tttgtggtgg ctgagtagag gcatgtgggg tcactcatgc gccctcgggg tccaggcccc    480
 actagtcctc ctccaagtcc cattttggct ggtnggacac ccaggtgtgt ggcctagagg    540
 ctatcaggct gcagcttggg gaagcaaaca agggagggtg atggttcctg gccccacacc    600
 atcattctgg tgtcagccct gagagggtgc ctgtcacagc aggttccagg actgctgcct    660
 cctgaggatg gagaaactgt ggcaccctgg gggccactaa gggaggccag ctgattgcag    720
 ccacgtgtac cttcctcttc tcgtctctgt gttttgtaga tgaccgcacc tcgagcagga    780
 gtggggatgc cacgtctgcc cccagcgccc ggccctctgt ccaccacggt cattcccgga    840
 gccgccccga ccctgtccgt gcccacacca gatggcgccc tcggaaccgc ccggagaaac    900
 caggtgtggt ttggcctccg agtccccccc accgcctgct gtgggcacag cactcagccg    960
 cgagggggac agcgggtggg cagcaagact gcttcctttg cggcttcaga ccctgttcgc   1020
 tcctaggttc ctgtggtcca cgcgccgtct ccacacccac ttcctatact tgagttgatg   1080
 gttagaacct tgtcgtcacc ctgcagaagt acagtgcctt gaatgccagc ttttccgttc   1140
 cctgatgaaa agatatgtta aaaaaaatta tcggaaaagg tttcatttgc aattggcttg   1200
 tgcattgata atctttattt actgttttaa gttgcagaga tgtgaatggt ttacaaatct   1260
 gaagctgaag ttcaatcttt ggttttctgt tgtaaatgcc ttttacaaac attgaattag   1320
 ctaccttaag tattgaagag cttccattgc taggtgagcc ctgctttgtc ctcagtagag   1380
 tgccggttcc ctgggctcat ccaggggctg agagacggcg ggacgctggg gcagggcaca   1440
 ctggcggagc tgcttgctca gtagggaatg tcagttgttg cgctgggcca tgagaaatcc   1500
 gccagaaaac gttaggtgag cagacatgcc ccccatgcca gtgggctgct gtgagtgagg   1560
 ataaagtgtg tgttgggcat agaaaccctg gctgcccgcc caccctgtgg agacaagtgc   1620
 agctcct                                                             1627



      <210> 2239
      <211> 1659
      <212> DNA
      <213> Homo sapiens


      <400> 2239
 atggagacag agccttcaaa ggccaaagcc aatgacccag gatcagctgc agaaggtgtg     60
 gtcttcgcta gcatctcatc aggccttggg gaggtcacct tcctctccct cactgccttc    120
 taccccaggg ccgtgatctc ctggtggtcc tcagggactg ggggagctgg gctgctgggg    180
 gccctgtcct acctgggcct cacccaggcc ggcctctccc ctcagcagac cctgctgtcc    240
 atgctgggta tccctgccct gctgctggcc agcatccttc ggaaagctct ggacaagatc    300
 gcggaaatca agtctctgtt ggaagagagg cggattggcc acaagtattt gggcctccgc    360
 tattgtcctc cactgtatgt cctctacacg gatgcctttt ggagtgtgac tccttattcg    420
 gaggtgcata tagcatttac gatcttagag gaagtcagtc tttgtgattc caagttgatc    480
 catattatct tcgtgagact tgcatatgca tgtccaaggt ttaccgtttc ggcctgggcg    540
 gcgtcgatcc ccgagtacat ggttcgtatc agcctcctta cagcgcaggt agacatgacc    600
 atcataggta tcgccttcat gccctgccca cggcccctga tgcccacagt agcccccact    660
 gcagcccggg aaatgggtgt acatcacaca ggggactcag caggagaaaa actccacaga    720
 gcgtgctgtg ggcggggccg gctgtgcagg gagcaccggg tcctcgccct gcccctgtcc    780
 tccacactcc cctacaggga ctgtgcccct ggctgcatcc tgcattttcc tccttttgtc    840
 cacaggtatg aggtagatga cattgatgaa gaaggcaaag cgagacacac cgtgagcttg    900
 cgccggatca tcccgctgac ccggtggaag gccaaccccg agacagaccc cgaggccttg    960
 ttagtcaagg agaaaaccat gttctcagga tgctgtaacc ttggtgacag cacggccaac   1020
 acaggaagcc tcggcaacac agccaagtgg gcccgggtgc ccaactacac caatatgcag   1080
 agactggtag tggccccgaa cgtcggtctg cgctgttatt tattggatac aaggctgaag   1140
 ggtcagggta aagaatgtga gtcacctcca atgatagggc tgaggtccat ttgtatgcac   1200
 acaaagaaaa gagtttcttc ctttcgagga aataaaattg gcctgaaaga cgtcattact   1260
 ctacggaggc atgtggaaac aaaagttaga gctaaaatcc gtaagaggaa ggtgacaacg   1320
 aaaatcaacc gtcatgacaa aatcaatgga aagaggaaga ccgccagaaa acagcttagc   1380
 ctctccccct gttcacagtg cctcaacctg gtgttcctgc tggcagacgt gtggttcggc   1440
 tttctgccaa gcatctacct cgtcttcctg atcattctgt atgaggggct cctgggaggc   1500
 gcagcctacg tgaacacctt ccacaacatc gccctggaga ccagtgatga gcaccgggag   1560
 tttgcaatgg cggccacctg catctctgac acactgggga tctccctgtc ggggctcctg   1620
 gctttgcctc tgcatgactt cctgtgccag ctctcctga                          1659



      <210> 2240
      <211> 774
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(774)
      <223> n = a,t,c or g


      <400> 2240
 atgaaaacac tattggcccg tgcatcaaga ttcctggctt tgccacgaac tagctttaat     60
 gcccttagta agtcacacaa cctcttgggt ttcaaggaca tccgcagtaa cgtggaagcc    120
 ttggcccaga agacccagcc ctctgtgttc cccaaggagt cagtccaagt tacaccagtt    180
 tgctatacta aaggagacag ggaaagtgtg cagaagtgtc cgcttatttt tagaagccac    240
 tcagccacag aacaggtgtc cataagaaga ggagtgattg ttcgtgtggc taagtggcga    300
 ggagagagtc acatccatgg agggcctgat gtgccaggcc ttgtcctaga cacctcttat    360
 gaaacatcac ctttaatcca cacaccagcc ctgagagtgt attacattgg agaagacatt    420
 gcaatggaac aagtcactaa cctagcattt cccctgctat attccaactc ccatagggtt    480
 tcagagcctg gggaactggg cttctggggt ccaggagagt cagtgatgcc ggcagatgct    540
 gtgtcagtgc cttgcacgtg ccatcctgga tcttacggag tccagcccct agtgctcaga    600
 atccaggggt actcaggcac tggacgttgg atctcagcat cagcaatgag ctgcatcatc    660
 tctgacagga atgggtgata agaacatttc cctttccttc tgacttcagt ctggcattct    720
 ggatttggaa ttccaccaca cggagctagt gctactctat nnnnnnnttt ccca          774



      <210> 2241
      <211> 501
      <212> DNA
      <213> Homo sapiens


      <400> 2241
 cagcgccttg ccttctctta ggctttgaag catttttgtc tgtgctccct gatcttcagt     60
 gtcaccacca tgaagttctt agcagtcctg gtactcttgg gagtttccat ctttctggtc    120
 tctgcccaga atccggacaa cagctgctcc agctgacacg gtatccagct tactggtcct    180
 gctgatgatg aagccccttg atgctgaaac cactgctgct gcaaccactg cgaccactgc    240
 tgctcctacc actgcaacca ccgctgcttc taccactgct cgtaaagaca ttccagtttt    300
 acccaaatgg gttggggatc tcccgaatag gtagagatgt gtccctgagg atgggaatca    360
 gctgtgacgt ctttgcaatt gtgtcacaga ctattgcatg cttacctgtg attttcatcc    420
 acactactta ccttgcctac gatatcccct ttatctctaa tcagtttatt ttctttcaaa    480
 taaaaaataa ctatgagcaa c                                              501



      <210> 2242
      <211> 435
      <212> DNA
      <213> Homo sapiens


      <400> 2242
 cccgggtcga cccacgcgtc cgagctcctc gttgtggaga caagatcaaa aatcatatgt     60
 atagaatgtg actgtggctc ccttaaagat tgtgccagtg atagatgttg tgagacctct    120
 tgtacccttt ctcttggcag tgtttgcaat acaggacttt gctgccataa gtgtaaatat    180
 gctgcccctg gagtggtttg cagagacttg ggtggtatat gtgatctacc ggaatactgt    240
 gatgggaaaa aggaagagtg tccaaatgac atctacatcc aggatggaac cccatgttca    300
 gcagtatctg tttgtataag aggaaactgc agtgaccgtg atatgcagtg tcaagccctt    360
 tttggctacc aagtgaaaga cggttcccca gcgtgctatc gaaaattgaa taggattggt    420
 aaccgatttg gaacg                                                     435



      <210> 2243
      <211> 1438
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1438)
      <223> n = a,t,c or g


      <400> 2243
 tttttttttt ttgggtgata gaaagtnttt ctttatttga atgtcattcc acctgcactg     60
 aagcttaaac ccagcagcag cagaaggggt caggaccaaa ataaatgtta ccaaattaga    120
 caatgaacag cgaggacaca ctcagacaaa acttactaat ggggtataga caacaccaag    180
 ctatcctaac agcacacagc acaggccctc ggaggcctgc ccatcagagc tctgcggaag    240
 gctcccttgt tccctgttca ggaaactcca gtcccaccca aaggttagct gtgggccagg    300
 caggggcctg cagaagtttc tggtgctggg aagatcccag cttctccaaa gacagggttt    360
 ccctttctct ttctcagttc acactggaag ctggagaaag gttattcccc gtgtgcccaa    420
 gcaggatgct caaaaggcca gggactctcc ccacagcctt atctaaaagt tctcatcatc    480
 ttgggctatc aggcctgaaa aggatcttga ttctttggtc cctcaccccc ctcaaggaaa    540
 gttttccctt ccatgggtac cggtccccaa agacgaaagt tttcatagcc ccggttccca    600
 gaaggactca actgaccaga ctgtgggcca gggactgaac cacccctagg ctgtggctgc    660
 cgtggcctct cctgagtccc cagatcaggc agagaaaagc gggcaatggc agacccctga    720
 tcacagttag gggggtcaca gttagggggg gacttctctt gggacctgaa gccggaaggc    780
 tctaggttgg ggcccaacaa ggccctcctg gggtcagaaa caggcactga tctcctctgc    840
 ttacctcctc ctgaaggcta aagccagatc gcccgacgag agcagaggca aaccacaaag    900
 cccccttccc atgatgtctt tattgcccca ggagggccat cagggcctca cctggggccc    960
 ccactggagc acctgccacc tgccccatcc acacctctgc agaacccagg gccccagtct   1020
 atggtttggt ccccactctg acttctaccc cttgcctgtg tcaccctggg gttcccgcag   1080
 acttcagccc acacaactct gccttcctga ctccaaactc cctggtgcat ctccccctgg   1140
 ctctgccaag atggcagctg gccaggtgcg gtggaatggg aatgttgcca ggctacccca   1200
 ccagggaact agcctccctc ctctccaccc ggcgctgacc cactcctaag tcagctggac   1260
 ccactacgtc ctctgaagtg gcttccttca ctccagttct tcccaaaagg atgcggcctt   1320
 ggctgcctgt gccccgggcc tccagcctct gaaaggtcag ttctatcccc cgcaccaggg   1380
 cacaggtttg gtgggtgtcc ttggggaaca aggtgtggca aggacacctg gtggcagg     1438



      <210> 2244
      <211> 454
      <212> DNA
      <213> Homo sapiens


      <400> 2244
 gagcgggcac ggcagcagca gtggcaccaa gtccagcaaa aagaaaaacc agaacatcgg     60
 ctacaagctg ggccaccggc gcgccctgtt cgaaaagcgc aagcggctca gcgactacgc    120
 gctcatcttc ggcatgttcg gcatcgtggt catggtcatc gagaccgagc tgtcgtgggg    180
 cgcctacgac aaggcgtcgc tgtattcctt agctctgaaa tgccttatca gtctctccac    240
 gatcatcctg ctcggtctga tcatcgtgta ccacgccagg gaaatacagt tgttcatggt    300
 ggacaatgga gcagatgact ggagaatagc catgacttat gagcgtattt tcttcatctg    360
 cttggaaata ctggtgtgtg ctattcatcc catacctggg aattatacat tcacatggac    420
 ggcccggctt gccttctcct atgccccatc caca                                454



      <210> 2245
      <211> 1317
      <212> DNA
      <213> Homo sapiens


      <400> 2245
 ggccctgaag ggatctcttg tccagaatta aacactgatc accagtggac cagagctgcc     60
 tggagcacat cttcactggg ctgcataatg gtttttaaaa aatcctggag cctctatttt    120
 agcatctcga tttgagatat gaagatccat gtttcttgag tttttcttaa acgacagaag    180
 attttgcttc ccagactagc atccctctgt ggctacaacc agcctgaacc gaggggtctg    240
 ccctttagaa gggcccagct cacgggctca ctgtgcactc aggccctagc cagcctgctg    300
 tacgtaggtg tttgcgattt catcattggc cttgttttaa cagacagcag agcagagcac    360
 ctgccataaa gcaagcctcg atgtgctaag tgccatgtgg agcccttgcc ctgctggggc    420
 tcgctgctcc catttgagct gccacagatc agcccctccc cccagggtct ccgaggagtc    480
 aggaccgcac agcctgccct cctagggaag gacttcctca gggaaggcag gcatgtggaa    540
 gccaggtgca gagtcctggc ctctccacac aggtgccgcc caggtgatgt ggtttgagaa    600
 gctgtatgct ggcctgcagt gcgtagagaa gtacctcatc taccccgccg tggtgctcaa    660
 cgccctcacg gtggacgccc acacagtcgt cagccacccg gacaagtact gcttctactg    720
 ccgggcgctg ctgatgaccg tggctgggct gaagctgctg cgctcagcct tctgctgccc    780
 cccacagcag tacctgacgt tggccttcac cgtcctgctc ttccactttg actacccgcg    840
 cctctcccag ggctttctgc ttgactactt cctcatgtcc ctgctttgca gcaagctgtg    900
 ggacttgctg tacaagctgc gtttcgtgct gacctacatc gcgccctggc agatcacctg    960
 gggctcggct ttccacgctt ttgcccagcc gtttgccgtg ccacactcgg ccatgctgtt   1020
 cgtccaggcc ctgctctcgg ggctcttctc cacgcctctc aacccactgc taggcagtgc   1080
 cgtcttcatc atgtcctacg ctcggcccct caagttctgg gagcgcgact acaacactaa   1140
 acgtgtggat cattccaaca cccgcctggt cacacagctg gacaggaacc ctggcgctga   1200
 tgacaacaac ctcaactcca tcttctatga gcacttgaca cgttcgctgc agcacacact   1260
 gtgtggggac ctggtgctgg gccgctgggg caactatggc cctggtgact gcttcgt      1317



      <210> 2246
      <211> 1143
      <212> DNA
      <213> Homo sapiens


      <400> 2246
 gtacccactg tggtggaatt cacaggatgg taaaataatc cagctgcctc cctgcaagac     60
 aggagcttgg atcgtgccgg ccatcatggc ctgctacctc ttagtggcaa acatcttgct    120
 ggtcaacctc ctcattgctg tctttaacaa tacatttttt gaagtaaaat cgatatccaa    180
 ccaagtctgg aagtttcaga ggtatcagct catcatgact ttccatgaaa ggccagttct    240
 gcccccacca ctgatcatct tcagccacat gaccatgata ttccagcacc tgtgctgccg    300
 atggaggaaa cacgagagcg acccggatga aagggactac ggcctgaaac tcttcataac    360
 cgatgatgag ctcaagaaag tacatgactt tgaagagcaa tgcatagaag aatacttcag    420
 agaaaaggat gatcggttca actcatctaa tgatgagagg atacgggtga cttcagaaag    480
 ggtggagaac atgtctatgc ggctggagga agtcaacgag agagagcact ccatgaaggc    540
 ttcactccag accgtggaca tccggctggc gcagctggaa gaccttatcg ggcgcatggc    600
 cacggccctg gagcgcctga caggtctgga gcgggccgag tccaacaaaa tccgctcgag    660
 gacctcgtca gactgcacgg acgcccgcct acattggccc gtcagagcag ctttaacaag    720
 ccaggaaagg gaacaccttt cagctcccaa gagaggatta gaaccctggc agaacatcct    780
 ctttattcag tataagccgg cagcaagcag ttctacctaa cgtcccacat ccttctcatg    840
 ccaacacttc tgtaattgat cattataaag aaaaaacaag gtaacagtca tagttcacct    900
 gtctcttatc tattcacttc tggtgccaca actgtttatc cttttttgaa gaaaataagg    960
 gaacagaaat gccctttttg tattgcaatc gaaatgaaag gaagaagtga tgttaaaaaa   1020
 caaaagtcaa gtgatttatt atatacaggg ggccgtcagg tctagtcgag caggctcagg   1080
 agaaagtaat taaaataatt ttatattttt ttatttattt tggatctcac ctgggctgga   1140
 tga                                                                 1143



      <210> 2247
      <211> 553
      <212> DNA
      <213> Homo sapiens


      <400> 2247
 aaaaagcgtc cgtgatcgtc cactctgacg tgaagccttt caaatgcaag ctttgtggga     60
 aggaattcaa ccggatgcac aacctgatgg gccacatgca cctgcactca tacagcaaac    120
 ccttcaagtg cctctattgc ccaagcaaat tcaccctgaa ggggaacctg acacgccaca    180
 tgaaagtcaa gcatggagtc atggagcggg gccttcattc ccaaggtctg ggaaggggga    240
 gaatcgccct ggcacaaaca gacggtgtcc tgaggagtct ggagcaagag gagccctttg    300
 acctctctca gaagcgccgg gccaaggtgc cggtgttcca gtcagacggg gagagtgccc    360
 aaggcagcca ctgccacgag gaggaagagg aggataactg ctacgaggtg gagccctaca    420
 gccctggcct ggccccccag agccagcagc tctgcacacc cgaggatctg tccaccaagt    480
 cggagcacgc ccccgaggtg ctggaagaag cctgcaagga ggagaaggag gatgcatcca    540
 agggagaatg gga                                                       553



      <210> 2248
      <211> 719
      <212> DNA
      <213> Homo sapiens


      <400> 2248
 gcaccacacc acctagtgcc cagaacatcg gcattgaatg gcgccataac aaaagactct     60
 ccccagggtc taatcataag atgatcaaac actttcattc aaaatgcagg actgaaactg    120
 tgatgactga agaggaggaa tggaagccca tggacccatc caagatgaga tgcagcttct    180
 tccagaatgg caaggagtct gagaaagaga aggtccccac aaggtctctt ctggctcaag    240
 tgattattcc gctagtaaat tacaggggcg atggctcaga tgccaccctc cagaatgcag    300
 accccttcgt gggaaaggcg gggctgggat ttgtggatga cagtcctctg aaggaggtca    360
 ggtgtcagag aggtctgatg gacaatgtgc acaagtctgt gtgtgagaag accaagaaag    420
 gcgaggctgt ccccgccctc tgcattctca tcctggataa cccaagctca tgttatcagc    480
 ctttcctggc atacccccgg tacgttaaac cgtcgtctga aatacccagc attctgccgt    540
 ggaaagaaaa cattgagctc ggaaaacagg ccactaacaa ctcgttcaca gagtatatgc    600
 tgaattgcgc tggtctagat ccttgccact caatgtgtgg ttcaaggacc aagatcatca    660
 tcattacctg tgaacttgca agaaatgcag aatctcaggc tccacctcac acctattga     719



      <210> 2249
      <211> 301
      <212> DNA
      <213> Homo sapiens


      <400> 2249
 ggatgagctc ccttcccaga tccgtgcctc tggacctggg ctgaaggctt ctactccctc     60
 cattgtcacc ttcgggaatc tgcttgttac cttcctccca agaatgttcc aaaaggtctt    120
 ggtttaattt ctggagggca ttcaagaact cagtcatctc acgtgtctag aaaagaaaca    180
 ttaaggccag gcacggtggc ttatgtcggt aatcccagca ctttggaagg ctgaagcagg    240
 aggaccactt gagcccagga gttcaagacc agcctgggca acatagccaa gatctcatct    300
 c                                                                    301



      <210> 2250
      <211> 1855
      <212> DNA
      <213> Homo sapiens


      <400> 2250
 gggcaaagat aaatagagtc acaaaaaaca gaacattgat ggccacaaca gcaacctggt     60
 caatatttcc ttggggaacc tgagcttcat ctgtacttgc ttcttcaaaa ttaatacttt    120
 tacactgtct tcctgagtca tccacacgat gttctcttag tatggcaagg atcagaataa    180
 tatttaaaat tcccaggaag gcgctaagta aaactggtgt tgtatacatg tttatctgca    240
 gtttaatcac atcccatgtc acaccttttt ctccaaggaa tgtaaaacaa gtctgaaaaa    300
 ctgctccaat tcccaacaat ccacgagcaa ccagcatgta gtatttatta tgagaagctg    360
 ggatgtggag atatgcatag aggcagttgg ctgccacgga aatcaagatg gagacaataa    420
 gaggctcttt tcttggtcta taattagacc ataaaccaaa tataggtgaa gctaccattt    480
 ggccaagact atatgaagca ataacccagc ccaaaaaact tgtatcagct gtcggatcaa    540
 tcttttggag atatggccat atggacatca tcactacaga aaaccctaca ctgctgagaa    600
 acatagtaag atataaaatc ctaatagatc tccatcggct cttataatgc tcttcagtct    660
 ctaaaatgtc ccattctctg cttccaggtg tgtcgcctaa gagcggctcc tgttcacttt    720
 cgttccgcag gccggccata gttacactcc ctacaaggcg tcttgcgccc aactctcgcg    780
 acacctgctt tctcccatcc cgggtggcgt gaagctggca aaacaagcct gtaagtgcgc    840
 gtgcgcacct gacggtcaga cgtaggcgga acgccccgag gtcataggcg gggtcacgcg    900
 gaaggccggg cagcgcaggg cgaaaggagg ctgtgtcctc agcctcctcc ctcggcacgc    960
 gcctcccatc ctgacgggga ctgagagccc aggagagctc ggggcgtgtc caaactgccg   1020
 cgccgccctg ctccgggttt gtcttcctcc ctccgtttct ccttccgctg tatctagcat   1080
 ttcggttcct ggaaaggtta ccggagctgc gattggggct gggaccaaag ttgagtcctg   1140
 gaaagggagc ctggagagcg gcggtgctgg gaggcccggc cagctcgatc gcaggcttcc   1200
 acctggcggc caatgcttgt ttgctactga tgggtgtgag caagttagat attctatacc   1260
 ggagacttct cctaacaaaa ctttttatca gaggatgggg aaggccagaa gatctcaaaa   1320
 gactctttga attcagaaag atgattggaa atcgggaaag atgccagaat ctggtttcaa   1380
 gcgattatcc agtacacatt gataagattg aagagcaatc agattgtaag atcttagatg   1440
 gacactttgt ttcccccatg gctcactatg tgcctgatat catgccaatt gaatctgtta   1500
 ttgcaaggtt ccaatttatt gtgcctaaag aatggaacag caaatataga cctgtatgca   1560
 ttcatcttgc tggaacagga gatcatcatt actggaggcg acgaacacta atggcccgtc   1620
 ctatgattaa agaagcccga atggcttctt tattgttaga aaacccttat tgatgacgtc   1680
 agactattca cagaagaaga aatgaaactg gtgcacagat ataaagaaat gttcaacgtt   1740
 gctggtaata aatgtagagt taaaacaaca atgatcaaat atttaaaaaa aaacagtact   1800
 ggtgaggctg ctttgaaatg ggcactcttg ttactaatga ctgaaaatta gttca        1855



      <210> 2251
      <211> 923
      <212> DNA
      <213> Homo sapiens


      <400> 2251
 tgcggccgcc ggccctcgcc accccgcctg cccactcccg ccgccgcccc gctctcgctt     60
 tccccccggc ctcccctcgc cccttcccct cccccttccc ggcgcactcg gggggctggg    120
 aacgagctgc catgtgatgc gcgtcccctc cgcgagcttt cggtgaccca cgaactgccc    180
 acctcgccgg ctgccgggag ggggtctgcg agccggtgaa gacgcgggga atgagggagg    240
 cggtaaaagg tacgcaaagt ttctccggtc gagttgcagc tgtctgcttc agaaagtgag    300
 ggctccagga atgagggaga atcttcaaga acttcctcgc actgtgacat gtctgatccc    360
 ttgctcccat ccctgcagca tgaacaaggt ggacactcac tgacctgtca caaggttgcc    420
 ccacaaaact ttggggtcca tgtctgaatg gattgccaga gccttctcat ctctcccttc    480
 gcgcagttcc ctgcatcgta agactcgaag gcagcacagg acctggaaaa attacatggt    540
 gtgaacggca tgtctgtgga tgagaagcct gactcccccc atgtatgtgt atgagtccac    600
 agtccactgc accaacatcc tcctgggcct caatgaccag cggaaaaagg atattctctg    660
 tgacgtgact ttgatcgtgg agaggaagga gttccgggcc caccgggctg tgctggccgc    720
 atgcagtgaa tatttttggc aggcgctggt tggacagaca aaaaatgatt tggtggtcag    780
 cttgcctgag gaggtacagt aatttggttt gtgtgattgt taatgaatgt ttattgactt    840
 acagaaaact ggctgactag gagctagaag atgtactagg tgccatgtcc ccactcagga    900
 gttgatgtcc aagtcacatg tta                                            923



      <210> 2252
      <211> 2367
      <212> DNA
      <213> Homo sapiens


      <400> 2252
 ctacactttc agtgccgcat attcatgaga tcctgggggc tcctgggtgg tgtctgaagc     60
 tgcctcagac agggcgctgg tgcttagctc agcataggtc actccttggg ggtctgccgt    120
 cgagagagat accctttcca tattggataa atctgcctcg gcagcctcct gctccggaag    180
 tttggaatgg ctggttcgag aaaatccttc actccccctc tctccctttg cgttctctga    240
 gctcactgtg ctggctgcat ctgtagatga tgaagactga gaggaagagg agaaggatgg    300
 agatgcagct gaagatggcg acaaagatgg ttctggtgtc tccattgcct tgtcctcttc    360
 aggatcactc ccagaacctt tgctctcagt caatgtagac cctgggatga ctccaggtct    420
 caggacactt cgatgtctca ctccatacaa tggaaccgaa tgtattgtaa ttgctcgatg    480
 caggatgagc aggaggcaga tgaggccaac ggcaaaggcc cagcacaggt aggtgaccgc    540
 caggcgtggg cggggcgggt agaagccata gaagagaggg gaccattcca ggtaaccctc    600
 acccgagagc aagttgaaga gctgggtggc aaaggtgacc aggccctggg agtgggggtt    660
 ataggagccg cagggcgagg agatgtcggg gccgggaggg cctgggggag cgcctcccaa    720
 ccaggtgggc agcagcgtca tgcaggccat gagcacagag gccagcacgt taagaaggag    780
 caggaagcgc agcagggaga agtaggactc cgtgccggcg ccaaactggc gagcctgcgg    840
 cggcagggat gcttcctggg cccctgagag tgcagagatt cctggatcca gagctgcggc    900
 tgggcggctg cagctgcgct tgttgaaaac aggttgaggc tcttggaaac acgggcttcg    960
 accacgtttg agggtacggc gccaggaccc gttaaactct cggggctcta agtgccagcg   1020
 cttcgccacc gcaaccggcc cccttccgcg gcgccagcgc gcagggcccc ggtgcgccgc   1080
 ccagccggca accgtgcaat ccacaagcag tgcctgctgc tcccaccgca ctcgcaccaa   1140
 caccaccacc cgggccaggg ccacgactcg ccgctcgcgg gcgtctaaga ccaagaaccg   1200
 gtcgagcctg cacaacaagg gcttgtataa cggttccctg cctgaacctg gtgccatggc   1260
 caccatgctg ctgctgtaag tcactctaga ggatcccact ttccagtctt tggctgttaa   1320
 cggctgacgc gcctctttct tcaccggcgc atcaccatcc accagaccgc cgccatcacg   1380
 aatgtaatcc agttcagctt tgctgatacc tttggtcagg cgcggcggct gataaacctt   1440
 aaaccaaatc agcgaccaga taatgccgat accaccagtg acaatgaaca cccagtgcca   1500
 gctcaacatc tcctgaatcc agatcagcag cggcgtcaga aacgccagac cgacaaactg   1560
 accagacgta taaaaaccaa cggcagaagc gcgttcatgt tccgggaacc agctggtcac   1620
 catccggtta ttggtcggga aagcaggcgc ttcgaaaata ccggttatcg cgcgcagacc   1680
 aattaatgac attaagcccg tggcaaagcc ctggaataaa gtcgccactg accagccaaa   1740
 tatcgcaata aaataagtca cgcgagaacc tacgcgatct aaaaaccaac cgccggggat   1800
 ctgacatagc gtataaagcc aggcgaaggc cgaaaataca tagcccattt ccgctttggt   1860
 aatgccgaac tcttcctgaa tatgggcgga agccacggcc aggttggcgc ggtcgacata   1920
 acaaatgact accgtaataa agatcatcac cagcgtcaga taacgccgac gccccggctt   1980
 tgctgcatta acgggaatat ccatagcgag ctttctccag attttgggca tagcgaagcc   2040
 gctcaccatg ccgctgttat cttcatgacg ccagagcgga ttacgccagt ccggggcatt   2100
 tttactgaac tcaatcactt tagcttcgtc gatttccacg cctaagcccg gtttcgttaa   2160
 cggtttaaag aagccgccga ccatgctgaa gtcttctttg tttttcacaa agtcgagtaa   2220
 ctccgcgcct ttgttgtaat gaattcccat actttgttcc tgaagtacgg cgttatagga   2280
 aacaaagtcg atatgcaggc aagccgccag tgcaatcggt ccgagcggac agtgcggcgc   2340
 aagggtcacg tcataggctt ctgccat                                       2367



      <210> 2253
      <211> 838
      <212> DNA
      <213> Homo sapiens


      <400> 2253
 ttaggtgagg aagagtttag ttattatttt ccaggaaggc aatgaaaggc acagactgca     60
 tatccaaaac ccagtggact gtataagaca atatcctcca gggcccagtg aagcgtaata    120
 gctccgagac agctactgat aattcaaatg acaaaagcca tagcatgaaa tacaggcctt    180
 gggcagcagc atctaaaaat aggaggtcct caggcatctc gggcaagatg gccacacttc    240
 tgttggcggt ggtcactccc catctacatt cccataacat gggcacatgc gggtactaca    300
 cccacactgc taccttgtgg agttctgttt cttcccctgg ggcactgggt tcttacaggg    360
 ggacattgga ttgctcagca actcctgtta ctagcactgg tcctcattaa tattttgcat    420
 ctctggatgt atgctgctcc acgtaggaac cactgcacac gtggctgtcg agcacttgat    480
 aggtggtgtc caggatgatg aggacttaga aatgaccata ggatgtcatg gtgaagagat    540
 gattggtgac cttgataaga acagttttgg cgctggtggt ttgtgcatcg gagagagagt    600
 aggagggcct gggtgctgtg aagtcctaat tagaatgact ccaacagagg atgtgggaga    660
 agagaggtct gacatgaagg gaatacaact gagcatgcaa gagaggacca gatgtagaca    720
 atttcctgaa ggaaggagac atcagctggg ccacctgctt cagggaggcc tgggaagagg    780
 ggaggcttgg aaatatcacc agatttggga agaaggtcac tggctattga gggagcag      838



      <210> 2254
      <211> 456
      <212> DNA
      <213> Homo sapiens


      <400> 2254
 ttgaagtgct agccacaggg gaatggtctt atttgaaacg accataattt cagctgtaac     60
 gttttgttct gtactgctgt cagcatactt ggaattagaa aatccacacc tgccatttga    120
 agttcatgtt tctttttctc cccttgccct tgtgtaccgt gtatggaatg atctatcttt    180
 aaacgtgatt gggaccaaat caagtcactg ggcatggaca ttcttctggc atactacccc    240
 tgaagaggga tggggagaac ttatagaggc agacacactg acagcagaaa aagtgacaga    300
 tgatagggag gaaggagaca gaaaacccaa aagccaatgt cgtgtattac agtacaacgt    360
 aagcatggaa cctcatgatg acagtgaatt atcagaaaag aacaaattat attgttttta    420
 aaaagggcac gaaatcgtcg acccgggacg tccgga                              456



      <210> 2255
      <211> 1606
      <212> DNA
      <213> Homo sapiens


      <400> 2255
 tttttttttt ttcgtatttc aagggttttt attctgagca gtaggtacaa aaaataatga     60
 catagttgtg tctaattctg tatagttcag gcaccctcca caggctgtca atctctgatt    120
 tgatctactt ttaccagatt taacagatcc ttgaatttac tttactgtat atacttcctt    180
 cttgctcaca ttgggaatca aactaatgct ggaaacatgc atcttcagac ttcattgagg    240
 aattccagat tgagacacgc tgggatgtgg attgagtcca tggttagaga agatggatta    300
 aatggaaaca aaacaggaaa catgtgcttg gcatctaata gcagttgctg agggtcattc    360
 cgctcttgta gttgtgcctg gattgttcgt ataaaggcca ctgttacccg ttcttcaaat    420
 tcattcaggg gagtataaag gtttaaaatt ttgacaatct gctgggtgct gagggaggta    480
 cacagggagc agatagcctc tgcgtcctcc tgggttttct tctttaattg caggagctgg    540
 gctgcttgga tcagaggttc catggtctga actgctccac tctggtgaag gtttcttccc    600
 cgaagccact cctcaagctg acttatattg tacctgagtt gcatgcctgt gctccaagag    660
 cagacgtcct tccgcaggag caggtcatta agagtcactg cgttgatcat gtagaagagc    720
 tgtttgaata cctgcaggat gatctcaggg tccaagccct ggtcacacat gactgtatga    780
 aaggcattca tctggcggat gatagcttcc aggcggtatg agttatcctc atctgccatg    840
 ctggaggagt gcttctggga gccagtgggc ttcacaccag atagaccctg aatgctctaa    900
 ttttccaaca tggcagaaac tatcatcggc tgtaacacac cctcggcaat tttaatgagc    960
 tgctggtaga tctgaatgga aaggtcacgt caggcacctg acggtattcg gtgaggtcaa   1020
 aattcttaag acagtgttca attctgcttt gcagtgttct gagtcatgaa gccctcatcc   1080
 ccgctgtact gcttcagaca gtgaagaagg cgggcaggtg ttggataacc agaatgacgt   1140
 catctcaaag tcatcattgt gctttttcag gactttctta atgccgttga tggtggaggt   1200
 cagcagggag tgcaccttga gatcgtcgtt ggtgtagtcc cgcgtgccgg atgcacatgt   1260
 agaggatgta ggcggggaga cagggcactg tgcccgacag catctggggc ttcaagtctg   1320
 tcaccaggtt ccggatgagg agggcctcgt cctctttgtg gtactccagc atgccctgga   1380
 aatccttctc tttccgctgg accgtgacct gcctgttgag ctcatggcgc ttcctctcac   1440
 tctgggccaa tgcctgggca gcttctaggt cctgggcttt cttcatgtaa atcttcagtt   1500
 gctttttgag cttcctctca ttcttttcca gcttttctac cagttcttta aggtccagat   1560
 tctcgttggt cagccgggat atttcctgct gaacgccgct cgtgcc                  1606



      <210> 2256
      <211> 615
      <212> DNA
      <213> Homo sapiens


      <400> 2256
 atgcaagggc tggtgaatta ccagatctcc atcaagtgca gtaaccagtt caagttggaa     60
 gtgtgtcttt tgaatgcaga aaacaaagtc gtggacaacc aggctgggac ccagggccag    120
 ctgaaggtgc tgggtgccaa cctctggtgg ccgtacctga tgcacgaaca ccccgcctac    180
 ctgtactcgt gggaggtgcg gctgactgca cagaagtcac tggggccttt gacttctaca    240
 cactccctgt ggggctccgc actgtgcccg tcaccgagag ccagtgggat ggtgattgct    300
 cacaccaaag ccttggaccc ctcccagcct gtgacctttg tgaccaacgt cacctatgca    360
 gcagacaagg ggcctttatg ggaagtagca gcaccatcca gttctcagag agcaagctct    420
 ggagtaactg agctaacccg ggttacccca gtggatttac agattgaggt tagaacccag    480
 cagggttctc ttcctggaaa gaatagcctt ccctctaagg tttcaaatag accctggaaa    540
 catcggtatt tgattaaact tgaggaatgg attgttccta attttaatac tacctcaagt    600
 gaaagtcctg tttaa                                                     615



      <210> 2257
      <211> 418
      <212> DNA
      <213> Homo sapiens


      <400> 2257
 tttcgtgtgg atctcataca tcgtgtcggc gccatatgac acggtgccca ggtgcagccg     60
 cttaaatatc atttcattct gggtgagggg tcctgttttg tctgtcaata aatacaccac    120
 gcgcccaagt tcctctggga tagtgctggt ccgaacgacc gtgccaggga tgttctcatc    180
 tttcatcatc atccatccat acaccgcttt gcccatgtcc aagttcacac gcaaacttat    240
 ggtaatgatg taagaaaaga ggggaaggaa ccgaaaaaga ttgcggtacc atgggcccac    300
 aaatccttgt atggttacca taacaatgga atgagcaact aaagccataa atagcgcttt    360
 cgtcagccga ttgagttcaa ggtccaacaa accaacctta ttttttggat tggatgtg      418



      <210> 2258
      <211> 573
      <212> DNA
      <213> Homo sapiens


      <400> 2258
 atgtctgcag catgtgggca gaactacacc ttggccttga tggaaatggg ctccgtgttt     60
 gcgtttgggg agaacaagat ggggcagctg ggccttggca acctgacaga cactatcccc    120
 agccccgcac agataatata caatggccag ccaattacca aaatggcctt tggggctgaa    180
 ttcagtatga taatggactg caaaggaaac ctctattcct ttgggtgcca tgaatatggt    240
 cagctgggac acaactcgga tgggaagttc atcgcccggg cacggcggac agatggctat    300
 ggccggctgg gccacgcaga gcaggatgag atggtccccc acctggtgaa gctgtttgac    360
 ttccctggac atcgggtgtc ccagatctat actggttaca cctgctcctt tgccatcagt    420
 gaagtgggtg gtctgttttt ccagggggcc accaacacct cccgtgaatc taccacatac    480
 ccaaaagcag tgcaggacct ctgtggctgg ataatccaga gcctggcttg tgggaagagc    540
 agcatcattg tggccaccga gagagcacca tag                                 573



      <210> 2259
      <211> 737
      <212> DNA
      <213> Homo sapiens


      <400> 2259
 ggcacgaggg gccgtcagcc ttgccggagc cagacgtccg ctgtgccgtc ctcacagcaa     60
 ggcctgctcc gaggccccgg ggtgcgtcag cagccctcct caaacaccct gggagtgccc    120
 agcagggcgg aacacaccgg gaaaccaaca ccccaaaggc acaaggaagt atccctggag    180
 ctaaaaatag ttctggaaac ttgccacggg gccacaggct gggacgtgcg ttaaggctcc    240
 ctggccaggc tctgggttgg tgtaatgtgg aaggggcgcc caggtcggcc ctgggaggac    300
 atgaacaggc ttatgccgag ggctctcaga tgtatttacc tctgtgcctg gcagctggcc    360
 cgtggtgaca ggcagagctg gaggctggcc atcttggaag gcggccgaag gcccatgtgt    420
 cctcttggcc tctggccccg gagggcggat ggggatgtgg aagttgctga cagagcattt    480
 tctgagctgt tgggtcaggg gctggggggt ctacagtgca cggaagctca gcagagttgt    540
 tcactcccat gcatctgcac aaaggggagc taggcttggg agggggccca cgtgttcaca    600
 acctcaccct caagttgcca ctcctgggtt agagactatg ccagggttgg cctgccccct    660
 ttacctcttc cctgccccca gagagccttg cttggattgt gggaggtgtg gaaaggagct    720
 tatagccctg cgatctc                                                   737



      <210> 2260
      <211> 437
      <212> DNA
      <213> Homo sapiens


      <400> 2260
 ctgggcccag caggcagcgg agggctcccc tctgcgaggc acaggcccct ctgacaccag     60
 cagtggacct ggtcagcacc tctggggctg ggacatcagt gtccgtgttc tccatggact    120
 tgctggcgac tcccacgaga aggccagcca ggagggcgag gtgccgcagc gccatgccag    180
 gagcagatgc gcagagcctg cccctccagg atggggacta ccgacatcag ccctttgccc    240
 gcctgggtgt tcaggggtta gctctgggag ctcatgggct cagctgagcc ctgcagaccc    300
 cggcccagtc ctagaagtga aatgcgtgcc gacaagagca cggaatataa ctggagtccg    360
 ctcgctgagg ttctgtgaag tacatttaat ctccagagga accacccggc acgaaatcgt    420
 cgacccggga actccgc                                                   437



      <210> 2261
      <211> 591
      <212> DNA
      <213> Homo sapiens


      <400> 2261
 gcccggaatt ctcgggtcga cgatttcgtg gctttctgtc ctctgtggcc ccttgcctcc     60
 ctcctggtcg tgtgtgcccc cgagatggag cgggggcctg tgacttgcac acaggcacag    120
 actgtacgag ggagaacagg acaccgtcgg cgttttggac caggcgccca cggcctgcga    180
 gaggagcccg agtttgtgac ggcaagagct ggggagagcg tggtcctgcg atgcgacgtg    240
 atccacccag tgacgggaca gcccccaccc tatgtcgtag agtggttcaa gttcggggtc    300
 cccatcccta tcttcatcaa gtttggctac tacccgccgc acgtggaccc tgagtatgca    360
 gagcagtcct gctttcaggc accctccttc cccagccctt ccccggcgga ggagctccgg    420
 gttgtgagtg ctagacatgg gctgtgccag gccctggatg cctcatggtt ctgcacaggg    480
 gtccaacggc agccctggac tcagccaccc actgggtacc acctggccca gagagcagga    540
 gatttgtacc ctgtgggctt cccaaaagag acctattttg aaaaagttta a             591



      <210> 2262
      <211> 1635
      <212> DNA
      <213> Homo sapiens


      <400> 2262
 atggtgcaaa tgaaggatgt gggcctccgg agcccgtcgt ggccacgagc tcttgggccg     60
 tgcaatgctg tggtccagga tgggaaggct gtgcgtcgtg atgcgcctgt ccccctgaga    120
 cctcgccttc tgtgccaaca acatcaccat cctcaggcat cctgccggga ttcgagtcct    180
 accttggaca ggcgccgtat ctgtaggccg cttccctgtc tgtgcaatgg cgagagtaca    240
 gtgtatgaga tgccatggca ccgcactaag tcagtgtgtc ttcgtgtgtc tgagtcagct    300
 caggctgacc acaacgcccc acagactggg cggcttacac gggacgttgg tcatccccac    360
 cagtgtgtca gtgtcctcat ctccttaaag gacaccagtc ctactaggag ggctctgcac    420
 cacatcttca cctgcagctt ccgtgtctgt acccccagcc tctcctttcc tcgtctgcat    480
 cccagcacct gtgacaacaa agggcttgta agaagtgctg agggacagca gcacgctggt    540
 cacattcttc tcgccttgcc tttcccacgt aacaacaccc cctggagacg gtgccacggc    600
 agctcccaga gacgctccct gcacctgact gcagccacat gtcctcgctg caaggctgtt    660
 acgcggcaca cactgcaggc tcctactgtg ccacgaggtc tccggcagag gggcttgcgg    720
 gtgcaaggaa acccacaggc ccacacctgc aatgctggtg tgggtgtgga ggggcagctg    780
 cttgtttcct gctcctcccc gagcatcaaa gcacgcgggt ggcacagcag ggagagtaac    840
 caagagcagt cccaccccct ggggggcagt gcagctgtga atgccaccat cggagatggg    900
 aaagcaccag gggcagctgt gtcgctcaca tccacgctcg ccttaccagc gtggatgcac    960
 agagtcccag ggagcctgga gaaagcccgg cagctgcagc gacacttaca gtacccatgg   1020
 caaacaggga cgcgtgtgga ggctctggcc agcaccagca acagaatccc agtgcaggcc   1080
 tcgaggactt gggagcgcat ccaggccctt ctccgcagaa tactggaagt cagaggttac   1140
 ccagaatata aaacctgccc caaaatggca aatctatttg cataccagag gttaaaagca   1200
 atgtcagagg aggtgcttag aaacagaagt gtggaaactc tcaaagctcc aaatttccac   1260
 aaaggcttca aaccgacagg acaggtccac cttctcagcc ccacccagga aaagtcaatt   1320
 gatgtggtaa acttcattgt tgtcttattt tcagaaattg ccacagtcac cccagccttc   1380
 ggcaaccacc gctctcatca gtcagcagcc atcaacattg aatcctcagc cgtggcctgg   1440
 ttcctgtcct gggggctgac cagccttctg gggcctggga cctggggcat cgctgctgcc   1500
 tgccgtctgg cctcagggca cctgcaaggc cggaacctgc tggacgtccg tgtgtcccac   1560
 tccatcaggc ctggagaccc gggaggccag cagcagagcc acactctatt ctgtgtcctc   1620
 atcaccaagc actag                                                    1635



      <210> 2263
      <211> 888
      <212> DNA
      <213> Homo sapiens


      <400> 2263
 atgaggattc ggcgatggag ccttatgttt gacagtgttt ggcccatgtg tgccttctac     60
 agctgggcta aagcttctag aacattcctg aaagcagatg ggctccctag aaggaagcag    120
 tgggttcttg tagaggcctt ggcaggtgga ggagttcttg gggtcaaaca aattacaatt    180
 caggttctgt ttgaggtgct cctgagaaga ggaaaagagt cagaaaccta cacaaagatg    240
 tatagaagat taggtcctga gagatgccgg agatcaaagt atgctggggt tgaaaggatt    300
 gtagacaaga ggaagaacaa gaaaggaaaa tgggagtatc ttatccgatg gaaaggctac    360
 gggagcaccg aggacacgtg ggagccggag caccacctct tgcactgtga ggagtttatt    420
 gatgaattca atgggttgca catgtccaag gacaagagga tcaagtcagg gaagcagtcc    480
 agtacctcca agctgctgcg tgacagtcga ggcccgtcgg ttgagaaact gtcccacaga    540
 ccttcagatc ctggaaagag caaggggacc tcccataaac ggaagcgaat taaccctccc    600
 ctggccaagc caaaaaaagg gtattcaggc aagccctctt caggaggtga cagggccacc    660
 aagacggtgt cttacaggac tacccccagt ggtttgcaaa taatgcccct gaaaaagtct    720
 cagaacggga tggaaaatgg ggacgccggc tctgagaagg atgagaggca ctttggaaat    780
 gggtcccatc agcctggctt ggatttgaat gatcatgttg gagagcaaga tatgggtgaa    840
 tgtgacgtga atcacgctac actggcggag aacgggctcg gtttgtag                 888



      <210> 2264
      <211> 3009
      <212> DNA
      <213> Homo sapiens


      <400> 2264
 cagtccggcc gggcggagct aggggcgggc ccctgcgtct ctgggcgctg gagcgcggcg     60
 actatcacgc cgcgtggcgg acggacggac tgacggacgc gcagccttac ccgaaaggcc    120
 atggcggagc acgcccctcg ccgctgctgc ctgggctggg acttcagcac gcagcaggta    180
 aaggttgttg ctgttgatgc agagttgaat gtcttctatg aggaaagtgt gcattttgac    240
 agagatcttc cagaatttgg gcatgtactt gatgtgcatg gtgttcatgt gcacaaggat    300
 gggctgacgg tcacttctcc agtactaatg tgggtccagg cactggatat catcttggag    360
 aagatgaagg cttcgggctt cgaattctct caagtcctag ccttgtccgg ggcgggccag    420
 caacacggaa gtatatactg gaaggctgga gcccagcagg cactgacaag cttatcacca    480
 gacctccggc tacaccagca gcttcaggac tgtttctcca tcagcgactg cccggtgtgg    540
 atggactcca gcaccacagc ccagtgccgc cagctggagg ctgctgtggg tggtgctcag    600
 gctctcagct gcctcacggg gtcccgtgcc tatgagttca acctggtttg tgatcggaag    660
 cacctgaagg acaccacaca gtcagtgttc atggctgggc tccttgttgg caccctcatg    720
 tttgggcccc tctgcgaccg gattggccgc aaggccacaa tcctggcgca gctgctcctc    780
 ttcaccctca tcggcctggc cacagctttt gtgcccagct ttgagctcta catggccctg    840
 cgctttgctg tggctactgc cgtcgctgga cttagcttca gcaatgtcac cctactgaca    900
 gaatgggtgg ggccctcatg gaggacgcag gccgtggtcc tggcccagtg caacttctcc    960
 ctcgggcaga tggtgcttgc gggactcgcc tacggtttcc gcaactggag gctccttcag   1020
 atcaccggca ctgcgcctgg cttactgctc ttcttctact tctgggctct gccagaatct   1080
 gcacgttggc tcctgacccg tgggaggatg gacgaggcga tacaactgat ccagaaaacg   1140
 gcctcggtca ataggcggaa actctccccg gagctcatga accagctggt cccagagaag   1200
 acaggcccct cagggaatgc cctggatctg ttcagacacc cccagctccg gaaggtgacc   1260
 ctgattatct tctgtgtctg gtttgtggac agtctggggt actacggcct gagcctccaa   1320
 gtgggggact tcggcctgga cgtctatctg acgcagctca tctttggagc tgttgaggtg   1380
 cctgcccgct gttccagcat cttcatgatg cagaggtttg gccgcaagtg gagccagttg   1440
 gggaccttgg tcttgggtgg cctgatgtgt atcatcatca tcttcatccc agcagatctg   1500
 cccgtggtgg tcaccatgct ggctgtggtg gggaaaatgg ccacagctgc tgcctttacc   1560
 atctcctatg tgtactctgc cgagcttttc cccaccatcc tccggcagac aggcatgggg   1620
 ctggtgggca tcttctcacg gatcgggggc atcctcacac cacttgtgat cctgctggga   1680
 gagtaccacg ctgccctccc catgctcatc tacggcagcc tccccatcgt ggccggcctg   1740
 ctgtgcaccc tgctgccaga gacgcatggc cagggcctga aagacaccct ccaggacctg   1800
 gagctggggc ctcacccacg gtcccccaaa tcagtgccct cagagaagga aacagaggcc   1860
 aagggaagaa cttccagccc gggagtggcc tttgtcagcc tgggcaccag tgacaccctg   1920
 tttctctggc tccaagagcc catgcctgcc ctggaaggcc acatcttctg caacccggtt   1980
 gactcccagc actacatggc actcctgtgc tttaaaaatg gctccctcat gagagagaag   2040
 atccgcaacg agtctgtatc ccgttcctgg agcgatttct ctaaggcact gcagtccaca   2100
 gagatgggca acggtggaaa cctgggtttt tattttgatg taatggagat cacccctgaa   2160
 attattggac gtcataggtt taacacagaa aaccacaagt actttaaagg aaaaggtgcc   2220
 cccggtcacc ccatgccctc tttgaaggca aattttgatt tgcttgcctg tctgcggggc   2280
 gttggcagca gcacactgct cctctggcca gcagtcctgg gtgcacagac caggcaagct   2340
 ggtgtcaacg aagggcggtc acaggtagct gacttccttc ggatccccgt cactgggtgc   2400
 ccagaacagc gcaggaaccc gccgagtcct ccggcccctc tgggcaccgg gggtcctgcc   2460
 gaggagcgcc tgcagtttcc tggggtagct gggtccaggc ggggtcgagg ccgcatcttg   2520
 cgagcgggtg gcattggcag ggcatctccg ggcgagggca ccggcgcccc acggccgcgc   2580
 gcagggcagg ggcgcggggg ccccgggaag cccgagagcg gaggaggcgg ccccgtggcc   2640
 ctgcggccag gcgactgtac ctgctgcgtg ctgaagtccc agcccaggca gcagcggcga   2700
 ggggcgtgct ccgccatggc ctttcgggta aggctgcgcg tccgtcagtc cgtccgtccg   2760
 ccacgcggcg tgatagtcgc cgcgctccag cgcccagaga cgcaggggcc cgcccctagc   2820
 tccgcccggc cggactgtgg accggagtca cgaggcgggc ttgcgctctg gcgccgcctg   2880
 cggggctacg cgagccggga ccgcgtcctg tgcaatcgac ggtgccccca cgcagcccgc   2940
 tttccttcga agcgcacccc ctctggttct ccccatcttc atcttatgtc ttcatgggcc   3000
 gtgccctga                                                           3009



      <210> 2265
      <211> 1308
      <212> DNA
      <213> Homo sapiens


      <400> 2265
 atgtaccaat tgttaacact tttgccacat tggctgaacc atttgaaaag ccttttgtct     60
 tcctggagtc agtggtgagg ctggtgatgg atgagggtta tctgatgggg aatggacctc    120
 ccataaggga agtagtatca gaaaagtatt cttgtgagga aaacacagag gagaacaaag    180
 agagcaggtt gatggttcta accttggaga gtgtggagga aaacagggca ctgacagcag    240
 cagagggcat gacatactcc tttgcaggat ttcttcgttt ccaagcaaat accctgtaca    300
 tcctggactg gtggagccag cgagaggctg gagctggagc ctatcggctg ggccccgcct    360
 cgcctcaggg gacactgctc ggagacaaag cccggggccc tggccaaggg caccgcggag    420
 gcgccttccc agacgcggat gacgtggctg tcctgactga cgggaaggaa aatggctgct    480
 cgcccagctc catcaccagc agcggcttgt ggacaactcg cccacgcatc cctggtggcg    540
 gtccctgaag cccccgcggg gtcaggagca cgagcacttg ccaggggacg cctggggcgc    600
 ccctcctccc agaagctccc gcggaagact ggagcaggcc acctggctgc ggataatggg    660
 aaccacagag tgagagaact ccacatcggc ctgaaggaag agcatgtgaa ggaagactca    720
 gaaacagagc ctcatcagga agaggaagag gaggaagaag aagaagaaga ggaagaggaa    780
 gaggaggagg aggaggagga agaaaagaag aagaagaaga aacagtttct ccactggaga    840
 cacaccttga gttcagggag acatctctcc acacttggac catcttcaca gaccctggca    900
 gcagtcgatg ggcaaagctg tgtaacagtg atggccgttt accattgcct ggtattcatt    960
 gtccagcacg atgatgtgga gctcaaatac tctgccatcc tcagcgggca tattgttgga   1020
 tctctcctca cacttccagg cccacactca tggctgttca tgatcaccca atggccaaag   1080
 tacactcaga aatggaaggc gatgtctgag tgctcatcgt ccccctgtgg aaatgcacct   1140
 gcagctgtgg gttgttgatg aaagggagga ttggtgtccc tctctcatgc aagaaccagt   1200
 agacaaagac acaggccatg tgtggggcat gggcaacagt gatactgttg tctccctctg   1260
 ggcagctcct atgaattgtg accagtcttc tccatggtta cttctaag                1308



      <210> 2266
      <211> 1226
      <212> DNA
      <213> Homo sapiens


      <400> 2266
 atccctcggg tcgacgattt cgacagactg ggccaatcat tacctagcca aatccggcca     60
 caagcgtctc atcagggatc tccagcaaga tgtgacagat ggcgtgctcc tggcccagat    120
 tatccaggtt gtggcaaatg aaaagattga agacatcaat ggctgtccga agaacagatc    180
 ccaaatgatt gaaaacatag atgcctgctt gaatttcctg gcagctaagg gaataaacat    240
 ccaggggctg tctgcagaag agatcaagaa tggaaacctc aaggccattc taggcctctt    300
 cttcagcctc tcccgataca agcagcagca gcagcagccc cagaagcagc acctctcctc    360
 acctctgccg cccgccgtat cccaggtggc cggggccccc tcccagtgcc aggctggcac    420
 ccctcagcaa gccccagggg tgccagtcac tccccaagcc ccgtgccagc ctcaccagcc    480
 agcaccacat cagcagtcaa aagcacaagc tgaaatgcag tccagacttc caggtcctac    540
 cgcgagggta tccgctgcag gcagcgaggc caaaacacgc ggagggtcaa ctactgctaa    600
 caaccgacgc agccagagct ttaacaacta tgataaatcc aaaccagtca cctccccacc    660
 cccaccgcca agcagccacg agaaagagcc tttggcaagt tcagcctcct cccaccccgg    720
 aatgagtgac aatgcacctg cttccttgga gagcggcagc agctccaccc ctactaattg    780
 cagtacctac tcgggcatac cgcattccgg tgcagccacc aagccttggc gcagcaaatc    840
 cctcagcgtg aagcacagtg ccacggtatc catgctctcg gtcaagcctc ctgggcctga    900
 ggcccccagg cccacacctg aagccatgaa gccggccccc aacaatcaga agtccatgct    960
 ggaaaagctg aaacttttca acagtaaagg gggctcaaag gcaggtgagg ggccggggtc   1020
 ccgggacaca agctgtgagc ggctggagac tctgcccagc ttcgaagaga gcgaggagct   1080
 ggaggccgcc agtcgcatgc tcaccaccgt gggccctgct tccagcagcc ccaagattgc   1140
 actcaagggc attgcccaga ggacttttag ccgggcactg accaacaaga agagttctct   1200
 gaaaggcaat gagaaaggga aagaga                                        1226



      <210> 2267
      <211> 742
      <212> DNA
      <213> Homo sapiens


      <400> 2267
 agagtggtgc acggtccgga tttcccgtgt cgacgatttc gtgcccattg agtgaggaag     60
 acaacggtac cccctctagc aatttttagc atatttggct gaaatgcaaa tacccaaaga    120
 gcgagacgca gggagggagc tcgcttagat aatctgtggt tggaacaggt catttcggtt    180
 ctgccgggcc ttgttaccca gggcttccgc tgtcactcag gaccgatggg acggggactg    240
 gagcctcatc caatcagggg cgctggggcg gggtcctgcc aactgtccat ccggggaagg    300
 ggaggccgca ttcccgcttt cctgactccc aggcgtcttg caccaaaggg aggtcgggat    360
 ctcggttttc cggccccgag agggaccagg tgcctccgcc atagcttctg tcgctccatc    420
 gcccgcactg tgactggact gttagaggga tccgtggaga ggaggccagg acacctggaa    480
 gccgggaaat ggattcagtg gtctttgagg atgtagatgt gaacttcacc caggaggagt    540
 gggctttgct ggatccttcc cagaagaatc tctacagaga tgtgatgcag gaaaccttca    600
 ggaacctggc ttctgtagga aaaaaatgga aagatcagaa aattgaagat gagtacaaaa    660
 atcccaggag aaacctaaga aattatgtgt accatttcag tcttaaaaag tggagttggt    720
 cgctgtacgc aagacagaca tt                                             742



      <210> 2268
      <211> 1258
      <212> DNA
      <213> Homo sapiens


      <400> 2268
 tttttttttt ttattggact gtaggttttt attaaaacaa acatttctca tagctctaag     60
 caaagcatta gaattcatca agcggactca catcttttct ctgcacagag agggctgaaa    120
 agggagagaa agtcccttat gtatgtctag atttggtaaa gcgaaggatt tcagcgaatg    180
 agtcactgag gctatacacg tttgcaaatt gtaaggcact ggcgggcaga gagcacagat    240
 aaaggacttc tggggtcccc catcctgtcc agcaacctcc cagctcacac cttagcttct    300
 accaagaagg gtgaacacag catccctgct atcttcactc agaccccaga agacacagga    360
 aaccgcacag ctccactccc accataactt attaggagat aagtcacatt ttatcaactt    420
 gccatcgcgc ctcctataga ttatacttcg gtaaacccaa tctgtataaa ttcctttgta    480
 ctttgtgcac tttaaatgcc acgattgtga atcacacaag cattgcccaa tttgttgaaa    540
 gcatttttac tggaacctca aaggcccacc atgtggggag caattatttt ttaataccca    600
 ctgggcagga cacgccggtg cccccaaggc cgcagtagcc attggggttc ttgctcaggt    660
 actgctggtg gtagtcttcc gcatagtaga aagtctgtcc ctcccggatg tcggtagtga    720
 tggggccgaa gccgtgctct gaaagaacct tttggtagtt ctctttggag ctcagggctg    780
 cctccatttg cttggcagag gtcgggtaga tggccgagcg gtactgagtg ccatggtcgt    840
 tcccctggcg cataccttgg gtcgggtcgt gattctccca gaagaccttg agcagttcct    900
 caaaactcat gtgttctggc tggtacacca ctcggacgac ttctgcatgg ccagtttttt    960
 ctgagcagac ttctttataa gtaggatttg aagtatagcc tcctgcaaaa ccaacttgag   1020
 ttgaatacac tcctttcaag acccagaatt tcctttcagc tccccagaaa catcccattc   1080
 caaatacagc catctgtgtt ccctctggga aaggttcgac tgttctgttg ccattgacat   1140
 gatgtttggc cgctacaggg gtctgttcct tccggcccgg caaggcctcc tgggggctga   1200
 cgatgttcga ggccgagttg cccatcctcg ggacgggaaa gaggctgtgg aggaggag     1258



      <210> 2269
      <211> 2806
      <212> DNA
      <213> Homo sapiens


      <400> 2269
 ttttttcagg tgctcaaact tttattttct tacaaaatgt tatagaaatg aacccaaact     60
 aaacagatat gtacatgtat atatgtacaa aattttactt ctgaaaaaga acctataaaa    120
 atagatcgta ttaaaaaaac ttaaaaagat ttaaaaccaa tactatgaaa ttgattttct    180
 taaagtaata gtaatcttaa attgcaggtt gtagttggtt ttccaggctt atttatatgt    240
 ttgattgtgg ttggatatat aaaggagttt ctttcatttc agaatgcctc cagtctcatt    300
 ttattatatc aaagagtcca gaattttttt tcccttcaca aatccttcaa catcaggaca    360
 aggcatgtta agttacaaat cacctttggt catcatcttc ttcttgagtc acaggtctga    420
 aaggcaatgt agtttgtcct ctttcaggat cagacattcg gagaattctt atcagtttac    480
 tggatggaag tgaactcatg ctttgaggtg tgagcaagat aaactgtcta aaacgctggg    540
 aatctgccat cttcagtatc aagtccatgg caattctcct attaaccata tccatgtaga    600
 catcaaattc atccaggcat ctgaaaggag attctgcgat ggaccacagg gaaagaataa    660
 aacacactgt ggagaaagaa cgttcacctc cagacaaggc tctcatgtca ttgaaagcag    720
 ctttatttcc ttctccaggc tgaactgata tacttagagt ttcattcttg tggtcaaaat    780
 tcatttttcc acaataggcc cgctgagata gtaagttgtc aaagtataat ttgcatcgta    840
 aagtcaaaca ccttctaaat tgttgatatg tcttgaatct gtgctccatg atttctccca    900
 gtaatttaat aaactttttt aaagtcctca ctttactatc cagatcaaga taggtctctc    960
 ttgcttcttg gtactgcctc attatttcct ctcgatctcc atgactagca tgttctgcct   1020
 gtatcttctg ccttaatcga ttaatttctt tgtccagaat tgatgcagat ttttctactt   1080
 ctatacgctc tgggcagatt tgtcttgctt gtgacatttt ctcctctagt tctttctctt   1140
 tcatatccag ttctcgtttc tttttattta aggtatccaa gtgttctttt tgtttttctt   1200
 cataatgtcg tttccctcgt ttttggttat ccacttcaga atcagcaagg tttaattcat   1260
 ccttaagtgg gtctgctagc tccgatagtt gattaatttt gaatttaatt gcatcatact   1320
 tattttctgc ttctattttc agacttttaa gatgctccat attttctttt tgttgctcca   1380
 tatgttcctc aaccattttc attttgcttt tattttcctg agcttcatct tccaaagttg   1440
 caatatctac agactggtgt tcttctatgt tctcaagttc ccgaatttca gaaatatttt   1500
 ttcttatttt catctttagt tctttataat gtagttggca ccttttaaga agttcctcat   1560
 tgtgtttaat atctttttca agggcagata aatgttgctg aagatttaat atctgggccg   1620
 tcttattttc aacctcattc tccaagtcac ttatttcaga atccacatct ctgcttagga   1680
 acttaggtct tgtattttca gatgaataat aacgtcctgc aaaaacttga tcaccatcag   1740
 cagtaaaagc ttctctacaa tttttgggtg gcttttggga ctgcattact gcacgagcta   1800
 cagaattatt tttgattagt agcactgtct ctatgcctct catgtcaatt aggctatttg   1860
 ccgcaaccgc attatctatt tctaaagctg tcagaactgt tggaaagtct ggatgataag   1920
 cagctctgtg tcttacatca tatatctcat tccgacactc agaaactatt atcggtggcc   1980
 gtgaggtcca tggtaaataa aaccttttca tgagtgcctg aaggaccctt tcatcagcat   2040
 gattatggca acaataggcc tgcagaagcc cttttaagca agattcaata gccaaagcaa   2100
 gttctgggtc ccgaagatga atgcaagctc ctaaagggcc tacaggttta taggtaaaat   2160
 gtccttgtct ataagcatca tctatggctt caagaagagc tggaacatta gggccaaatc   2220
 ttttgagtcg atcagtttta ctatctttca attctttcag ttgcccctga ttgtagctca   2280
 gtgcatgctt cacatctaat tcttctctct taattttgcc atgttcttct ttgtcctttt   2340
 ctatggcttg ctgaaactgt tcgatctctt gattgactga attttcttga ttttgaaagg   2400
 cctttactct ctcttttaac caagatattt ttttttgtct ttccaaccgt tcaggttcca   2460
 aagattggtc agtacttttt ttcagctctt caattcgttt acaaagctgc tcatcatctt   2520
 tctttaatgc tttatattcg tttaaggatc ggttatataa aacctcagct tcattatagg   2580
 cccttttctt agcaacaaca tctgctttca atgccataca ttctggtgct cgtgcatttg   2640
 tctcttcact aatcttttct agtttgtctt gaatatcctt gtacttttgt tctgcctcat   2700
 taagtctgac ctgctgttct tccattttcc tgtcaagtct agcagcacga tcttctccaa   2760
 ttttgatatt atctctgatg gcattcaatt gtttttcaat ttcatt                  2806



      <210> 2270
      <211> 1566
      <212> DNA
      <213> Homo sapiens


      <400> 2270
 tttttttttt ttgagaaaag ccggcataaa gcacttttat tgcaataata aaacttgaga     60
 ctcataaatg gtgctggggg aagggtgcag caacgatttc tcaccaaatc actacacagg    120
 acagcaaagg ggtgagaagg ggctgaggga ggaaaagcca ggaaactgag atcagcagag    180
 ggagccaagc atcaaaaaac aggagatgct gaagctgcga tgaccagcat cattttctta    240
 agagaacatt caaggatttg tcatgatggc tgggctttca ctgggtgtta agtctacaaa    300
 cagcaccttc aattgaaact gtcaattaaa gttcttaaga tttaggaagt ggtggagctt    360
 ggaaagttat gagattacaa aattcctgaa agtcccttag aaaaacccca ggatgaaaaa    420
 aaaaaaaggc cacaaagaag gcttcagagg tccctgctgg cccagggaca gatacctgta    480
 gtgtccagca ttgcagtgaa catgatctac tttcaaaggc agagggttta aggggagggt    540
 gggtgggaat ggtggaggca aaggctctcc ccatccccac ctcagtttta ggtagggctt    600
 ttaatttaac ccaaagacat ctctcaactt ggagagtaat tcagtcctca acagcgcctc    660
 aaatctgcta tggctttgca gcgcagcagc aagaatgttt aatatataat agataaaaat    720
 ttcatccaaa aaattaaaat aaaatattct tgcaaacccc ccccccaaca ccaattccta    780
 ttctaatgtt aacctaccac ttgtgctgtt aatacttgac catgtactta attggaaacc    840
 tatatccaaa agactgaaac tgaatcttca ccccaaaatg aaaacaaaat aaaatgagta    900
 acttgaggtt tatggcatat agtttaggta aacacacata cgaggagaaa ggggaagagg    960
 aaacagaggt gtcggaagca aagctgagtg acagaacaca ttcagtcagg gcagatgtct   1020
 atacaaagtg gagtggaaca tcaggaaaag ctccatatgg actcatgtgc acatgtctgg   1080
 aggcaccaga tccctccatg gcagatccaa gaacagggag ctaagggagg aggccattcc   1140
 tgtcattcca gttttagaag ctccacatcg aagacgagag tggcatgtgg tgggatgatg   1200
 cctgggtgcc cagtggcacc ataggcataa tctggagata tagtcagttt ggctctctga   1260
 cccacactca tctgggcaac cccttcttcc cagcctcgga tcacctcctg cttgcctagc   1320
 ataaacttaa agggcttgtt tctgtcccgg gaggaatcaa atttctttcc atcttcaagc   1380
 atcccggtgt agtgcaccac gcaggtctgg ccgcgcttgg ggaaggtgcg cccgtctcct   1440
 ggggagatgg tttccacctg cactcccatg gcggcggcgg acgctgagcg ggcgggcggc   1500
 gcgacgggcg gcgtggacca acagcgacct ggcggcggtt ccacggctct gcctagtacc   1560
 tcggcg                                                              1566



      <210> 2271
      <211> 656
      <212> DNA
      <213> Homo sapiens


      <400> 2271
 gaaatcactt ttatattgtc acatgggccc tctgcacaga gtccgatggc tcctcccggg     60
 gaagcctgat tttgtgacgt gtgtatagta aatgcaggcc ctctggcagc accataattg    120
 gtcggttacc ctgagcccag agctctgaaa gcatctgtgg aatgatcacg ggacccttct    180
 cctctgagaa ggctcccggc tgcctccccg ccaccgagct tgtagcctga atgcctggct    240
 gtcgcatgga gcattttgct tctggggtgt cttccttagc caaagggaac gtgtcatttg    300
 ctcgaccctg gcccaccctt gccgcccagc tgttgtgctg ggcacaggtc tggggcacag    360
 gcctccatga tgaagacgcg tgggctgtcg gtgctttcat ccgtcacaaa ctggcacctg    420
 tacctgacgt cccccctgga atgtacacca ttgaccggcc acatgccacc tggcatataa    480
 caggcattca tggtcacctc atagagcacc tggcatatag caactgctat acagctatca    540
 gcccatgtat ttgttgtcat taccagcaac ttcatcacta tcaccaacac caccatcatc    600
 atcaccacta tcgtcaccat catcaccatc accaccatca ttactgtcac caccat        656



      <210> 2272
      <211> 1699
      <212> DNA
      <213> Homo sapiens


      <400> 2272
 tagtcacaag gactgtgact aaggctcagt ccctgaggag tgccttggca tgggctgctt     60
 taggctgtaa acacccagtt ttatccactt tatgtgaaga aagccaacaa ggggcatgga    120
 gtgagttccg caggttttag cggctgcggc ggctggtgct cagtggggat gatggaggga    180
 aggcgcctcc ctctgcgggc cccgaggtct gtgcgggaat cagctctgca gctgtgtcca    240
 gggggagccg tagaccacac acggcaggct cacagctctg ttccatgaga actttataca    300
 caaaagcaga cgggctgggc ttggcctctg gatcataatc tgctgacccc tccctcctct    360
 ctgttttctc ctcactctcc tgccccacct cgacatccac agcgaggcaa tgaagaagcc    420
 cctgccaagg aagagcccgc ttctcagtgg gacaccggga aggtagacac ccaacagtca    480
 ccgctagtgg gaggcgattg tgcagaagca cgagggttgt tacaggatcg ggcaggtccc    540
 ctaccccagt ctcggactca gggtcctgtc tgaggcggcc accccgaagc gtggggtttg    600
 cggagacgta gggccgacct cccgcccccg ctgcgcgcgt ttctggccct gccagtgtct    660
 ccgccggttg aaagcgcgtg tctgcgtcgg gttctgttgg agtgcgttcg atgcgccgtg    720
 ggtccgcgct gcttccaccc aacttccagc agcaaacatc caggaaccca gaaaccatca    780
 gcacaggtgc ctgctgagtc ccatagaccc aataatggcc caccaggacc aaccaggaag    840
 caagtgtgga gctgggagtg agggagctgg gtgtggagat cagggggaag actgtcatct    900
 gaccagtgcc ccacagcagg accacgagca gggccaaggt gtctccaagg tgctgaggag    960
 ctgagcgctc agccagccca cggccacgat ggtgtgccgc cgaagccacg cggcttactt   1020
 cacagccagg atccgggatc aggctatgtc ccatgcagcc atgctgcttc catgtttttt   1080
 cagggatttc caacacagat tttcctgagt accctggatt aatctccttt tggataggtc   1140
 catgggggcc ctgctgcttt ttccccttag cccatggctc tctgggctga tggcagggcc   1200
 cggcacaagg taggaactga gtgtgagtgc gggatgcacc caggtctgaa atgctcagga   1260
 aggacccttg gttctcagac gatgcttgca acaacgccat gcgattcgcc cacttgaatt   1320
 tgaataagaa cgggctcagg tcagtgatta tcgctagtgc cttatcaacg ccctgtggct   1380
 tttcagcatt agtccccata tcctcgtccg ttgtggcact gagagcagct aactgttgcc   1440
 ctcgttggtt cccagttggc ttccgtgact ggtcagggtc aggtccactg ccaacaggct   1500
 ggtgttgaat cccttcctgc ctcaagcccc tctcccacgt ggtccagtca ccattctcca   1560
 cagagactac cctaaaaccc agcgactctc gtgtgcctgc agaatggcac agcccgttct   1620
 catagcagca ctcctgttta atcagaggga tgttaacgac caagtcatat ttgctcgatt   1680
 tgtgttcaat atatttcat                                                1699



      <210> 2273
      <211> 531
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(531)
      <223> n = a,t,c or g


      <400> 2273
 ggcacgagga agttttaaaa ctggacttta tttacctact agtgacatcg acctagtggt     60
 gtttgggaag tgggagaacc tacccctctg gactctggaa gaagctcttc ggaaacacaa    120
 agtcgcagat gaggattcgg tgaaagtttt agacaaagca actgtaccta ttattaaatt    180
 aacagattct tttactgaag tgaaagttga tatcagcttt aatgtacaga atggcgtgag    240
 agcagctgac ctcatcaaag attttaccaa gaaatatcct gtattgccat acttggtttt    300
 agtattgaaa caattcctat tgcagaggga ccttaatgaa gtatttacag gtggaattgg    360
 ttcttatagt ctctttttaa tggcagtcag tttccttcag ttacatccca gggaagatgc    420
 ttgcatcccc aatacaaact atggtgttct cttaatagaa ttttttgaat tatatggacg    480
 acacttcaat tatttaaaga ctgggcatcc ggtttaaagg gntgggtggt t             531



      <210> 2274
      <211> 999
      <212> DNA
      <213> Homo sapiens


      <400> 2274
 atccactatt ccgtgtggtg gaattcgcaa gctataagct ctgcaagtgg tgaccccgac     60
 gtgatcgcct tgaagttacg cttgaaggag gaaaactcat caattttcgg ggaatcccgt    120
 tcatcatctc cggatccctc tcagtggcag ccgagaagaa ccacaccagt tgcctggtga    180
 ggagcagcct gggcaccaac atcctcagcg tcatggcggc ctttgctggg acagccattc    240
 tgctcatgga ttttggtgtt accaaccggg atgtggacag gggctatctg gccgtgctta    300
 ctatcttcac tgtcctggag ttcttcacag cggtcattgc catgcacttc gggtgccaag    360
 ccatccatgc ccaggccagt gcacctgtga tcttcctgcc aaacgccttc agcgcagact    420
 tcaacatccc cagcccggca gcctctgcgc cccctgccta tgacaatgtg gcatatgccc    480
 aaggagtcgt ctgagtagca gatgtggcac ctgcgggtgg agtccagcct tttccctctg    540
 ggcccagcct ctccccaccc ccaccttgtt catcaggggc cagccccatc ccagctgccc    600
 tccctcacca catctacaca tactccggca tctgagtgaa gtgtccccag ggacatctct    660
 cccacacttt ccccagtgct ttctttctaa aagacaccgg gctgacgtca ggggtgtgtg    720
 tccttcagct ccctgagccc tgtcaccctt ccaggacacc caccttgtgc atctaagcat    780
 ttctctgctc attggggaaa tcctggcctc attggagact caggttcgag gcctgccctg    840
 accctcgggc ctcgggaagg tcagagagcc cggaatcctc cagaatggaa gagtcttgac    900
 tctggctttc cacaaaaagg ggcccataac aagggcccaa ggggctctca acaaaggggg    960
 gtaaggggcc cgtgggccca aaaagtcctc gctgggccc                           999



      <210> 2275
      <211> 445
      <212> DNA
      <213> Homo sapiens


      <400> 2275
 gtggaattct gatcagccag cgacccggtg acaggttggt gacactggat cacttccatc     60
 acggaagggg cagcattttg tcctcactgg aatagacact tactctagat cgggatttgc    120
 cttccctgta cgtcacgctc ctgccaaaac tagcatccgt ggactcacag aatgccgtac    180
 ctactgtcac ggtatgccac actgcactgc ttctgtctga ggaactccct tcacagcaaa    240
 gaaagtatgg taacgagccc atgctcatgg aattccccgg tacgaccatg ttgcccacca    300
 tcttgaagca gctggtttga taagatggtg gaatggcctt ttgaagactc cactacagca    360
 ccagctgggt ggcgatgcct tgcagggctg ggccagagtt ctgcaggagg cagtatatgc    420
 tctgaatcaa aactgagtgt aaggt                                          445



      <210> 2276
      <211> 465
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(465)
      <223> n = a,t,c or g


      <400> 2276
 aacaggggcc tggctacccc atccccctcc ccatgcccag tnccacgccc cctggcagcg     60
 ctcaaaccag tgaggctgca cagcttccag gaacatgtct tcaagcgagc tagcccttgt    120
 gagctgtgcc accagctcat cgtaggaaac tccaaacagg gcttgcgatg taagatgtgc    180
 aaagtcagcg tccacctctg gtgctctgag gagatctccc accagcaatg cccaggcaag    240
 acgtccacct ccttccgccg caacttcagt tcccctctcc tggtgcatga gccgccacca    300
 gtctgtgcca caagcaaaga gtccccaccc actggggaca gtgggaaggt ggaccctgtc    360
 tacgagaccc tgcgctatgg cacctccctg gcactgatga accgctccag tttcagcagc    420
 acctctgagt ccccgacaag gagcctgagt gagcgggatg agctg                    465



      <210> 2277
      <211> 655
      <212> DNA
      <213> Homo sapiens


      <400> 2277
 ctcgaccagc gtggtggaat tcgcacggct gaatgagcag agccggctgc tggagcagga     60
 acgctggcgg gtgactgccg agcagtccaa ggcggagtcc atgcagcgcg ccctagagga    120
 gcaaaggaag gtcacggccc agcagatggc catggaaagg gcggagctgg aacgggccaa    180
 gagcgccttg ctggaggagc agaagtctgt catgctcaag tgcggggagg agcggcggcg    240
 cctggctgcc gagtgggcgg agttctccgc gcagcaaaag ctgagtaagg agcgggccga    300
 gcgcgaggcc gagcgggcat tgcaggtgga cacccagcgg gagggcaccc tcatcagcct    360
 ggccaaggag caggctgagc tgaagatcag ggccagcgag ctccgggccg aggagaagca    420
 gctggcagcg ggagagagca gccctggagc aggagcggca ggagctgcgg ctggagaagg    480
 agaggatcaa cgccaccgcc ctgcgtgtca agctccgcgc cgaggaggtg gagagcatga    540
 gcaaggtggc ctccgagaag tacgaggagg gggagcgggc attgcgcgag gcccagcagg    600
 tgcaggcaga gcagcaggcc cggttgcagg cggtgcagca acagcaggag cggct         655



      <210> 2278
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(498)
      <223> n = a,t,c or g


      <400> 2278
 gtgcaattcc gctcggtggc ggtagccgcg gttgttggcc gaccgagtgc cggtataagc     60
 cccccccggt ggggggcagc tggtgtgcgg atcgcggcgg gagagaggcg cgggaggaac    120
 gggtccccgg agccgtgaac cgcgggtaca ggtgtcctgt ctgcgctctc tgccaagccg    180
 gcttgcttcc tgatctgttg ctagggccgc tggaccccgt tgctaaggac ccttgagatc    240
 gagtgaaagg gaagcaatgc agaaatcaga gggctctgga ggtacacagt tgaaaaacag    300
 agcaacaggt aactatgatc aaaggacatc atcaagcaca cagttaaaac acaggaatgc    360
 agttcaggga agcaaatcct cattgtcaac cagttctcca gagtctgcaa gaaaacttca    420
 tcctagacca agtgataaac tgaaccctan aacaattaat ccggtccatt cggatgatga    480
 agtgtttgaa agaggatt                                                  498



      <210> 2279
      <211> 854
      <212> DNA
      <213> Homo sapiens


      <400> 2279
 gactggtgga attctaacgt tacaatttag tcttcaggga acagaatatt cagcagcgct     60
 gtgatggaat ctgaggagtc actcagagcc ccgccccccc accaccccat acacagtgac    120
 tgagggactg tgcctcattg tgggcaaggg gtgagaaaac cccttcgtga tctgaagtgt    180
 ggctgtatct tgggaggtgg aaacacaagg ctgcttgctt gttctgaatt tcacatgtgc    240
 gtggaaggtg catgtggaag ctgagtgtca tatggtagct gggttagagc ctttttgtct    300
 ctcagctcca aagccactgt tcaccgcctt gctctgtgat catggcattg gactttgtca    360
 atgttctcct ctgccagtta gcagaggtga cactgggggt gctacgggaa gaaggggcat    420
 ccctcctggt tgcactgggc agcgctctct tcccatctgc agctgccgtg ggcaagcagg    480
 gttccatggg ggtgacttcc cacatgcaat gccctgtctg ccagcacccg agggacgtcc    540
 tgcttgccag tcctgtctca cattcccatg cctgccagcc ccagcctgct ggctgcagca    600
 actgccatct ggggcatctg acacggtctc cgccattcca agggctgctt ccactcctcc    660
 agtgagagcg agcctcggga ccagaggaac ggcccaaaca accaagcagc agccgccagg    720
 tctttatcac aggcctgctc tgggctgagc ggtgagatgg ggtctcttga aaagtgggca    780
 ctgaactgaa tgcactgagc taagaggcat ctcaggggat acctggcctc cagcagcacc    840
 aaaacggggt ccat                                                      854



      <210> 2280
      <211> 828
      <212> DNA
      <213> Homo sapiens


      <400> 2280
 atgaaacgat actcctatgg ttctgtttta tttactgcat tcgatcttgg ttatttagac     60
 cctgatgagg ttcagcaggg acacgaaatc ggaagacttt ttgatggtac agagcccatt    120
 gttttggaca gtctcaaaca gcactatttc attgacagag atggacagat gttcagatat    180
 atcttgaatt ttctacgaac atccaaactc ctcattcctg atgatttcaa gagaactttg    240
 gtgtttatat taccactcgc agcccctttc tcagttggcc ttgaggcttg cccattagct    300
 ggtaaacgtt tgaaagggtc agtgtgtcca gaactggaat ttccactttg gaaaaagcac    360
 agagtgttct cgcagtcttt gccttataaa actcatgcat tcaatgaaga gcggctgcaa    420
 gataacaaat cctacattca ctcagttctt caggagccaa gagaagatac tgatcctgag    480
 ggggctggag cagctccaga ccacagatca acatacaagc ttctgtctcc cgcattatcc    540
 ctcaaccttg gagaaaaaaa taagtggttg cgacgctata ttgaactttt aatttctgaa    600
 agggagatgg cagctgcagg tagcagcatc ccatcctgga cttcagtgtc catccaggtg    660
 aagttgagaa agtgtcagct ccagctactg gccaaggaag aggttgccac aattgtgtta    720
 gatgaaacat ctggagtcaa tgggatacat attgagcatc aacttcagtg tctaatacaa    780
 gtgcccaaac tctcagcccc aaatatcgcc cccccaaccc cagcctaa                 828



      <210> 2281
      <211> 438
      <212> DNA
      <213> Homo sapiens


      <400> 2281
 ttcgttgacc tctagtccag cgtggtggaa ttcgtttgcc cttgaacgag gcctccaata     60
 gactcttctg tgtgttctta atgagcagtt gtgaacatct ctttaggaac tcattgcctt    120
 ctgcggcagc atagggcatg ggctacctcc acgccaaggg aatcctacac aaggacctca    180
 agtcaaagaa cgtcttctat gacaacggca aagtggtcat cacggacttt ggactcttca    240
 gcatttctgg ggtgctgcag gctggcaggc gggaggacaa actgcgcatc cagaatggct    300
 ggctatgcca cctggcacca gagatcatcc gccagctgtc ccccgacaca gaggaggata    360
 agctcccctt ctccaagcac tctgacgtct ttgcccttgg cacaatctgg tatgaactcc    420
 acgccaggga atggcctt                                                  438



      <210> 2282
      <211> 1224
      <212> DNA
      <213> Homo sapiens


      <400> 2282
 ggtttttttt ttttttcttt tgggaaaggc attggccact ttggacttta ttagcaacag     60
 taatgtcccc tgacatacgc acaagcttgt agctccacgg ccaggtcttc ccccaacctc    120
 acaatggccc cgtgatgcag gcaggcaggc gagtgggggt ctcccctcct tatccacagg    180
 gccaccgaaa ggcccacgag acggccttgc ccgaggtcac ccagcggagt ggcttgctgg    240
 gagccctggg aataacagtc ccacacaagg ctctctccct ccgcagctgg acctgtacgc    300
 gggggctctg tttgtgcaca tctgcctggg ctggaacttc tacctctcca ccatcctcac    360
 gctcggcatc acagccctgt acaccatcgc aggtatggtg cctgcagcag ggaggtccac    420
 ccaggggacg tgtaaagggg tcagaaggcc acctccccct acaggcccga gggagcagcc    480
 caggaagtgg ccccagcagg agccccagaa gttcctcccc gtgtccctcc tccctggggc    540
 cagggccccc tccagcaacc ttgcttccac tggcaggggg cctggctgct gtaatctaca    600
 cggacgccct gcagacgctc atcatggtgg tgggggctgt catcctgaca atcaaaggtg    660
 aggacagagt ctgtggccat ggcggggctg tccccacagc gagccctttg gagtctggca    720
 ctgcccggca ctgtgcagga ttcatgccgt tggggttctg ggtagcatcg ctgggagtgg    780
 gtgggttcag gaggttgagc cactaggcag tcagcccccc tgctggcccc tcagggactg    840
 ccctggctgg tagaggctac ccaccctgct gccccgctgt taccagctct ggccctggca    900
 aggagctgac tcaggaactc agggccagcc acacccgcat tggctcagcg cttgatggtg    960
 aggtggggct gtaggcgggt gtgaaggcac acaaccagga ggccataaaa ctgcctgggc   1020
 agctcctcca attgtttaaa agcatgtaca aaatgccaag aggtgatgct acctcctgca   1080
 ggacaaaggc cagggaggaa agaagagagc tgggagagat tggcgatact agtctggaac   1140
 agataggaaa ctcacagggc tgcccggaga gagcgtgagc tcaccgtccc tggaagtatg   1200
 taagcagagc caggagctcg tgcc                                          1224



      <210> 2283
      <211> 446
      <212> DNA
      <213> Homo sapiens


      <400> 2283
 gagtccatta gtccagtgcg gtggaattcg tggagttaga ggcacctgct gctgtcactg     60
 agtgcagtga ctgggaagtg ctcatttgct cctgactgtg gagagctaaa gctgccagga    120
 gctgcctgcg cttgccaagt ggttgcagat gtttcctccc tactgctctg actttgccag    180
 atgcgggagc tgcggtgtga gaacgtcgcc acctgcctgg gcattttcgt gatctctggg    240
 gaacctgctt cggaaagagg tcctgcacct agactggacc ttcaaggcct ccctgctgct    300
 ggatttgatc tgcatgagat ccctccctgg gcctggcact gcagagctgc tatggacagc    360
 tcctgagctg ctgccggggc ctgggcgccc tgggcggcgc accctcacag gggacatctt    420
 cagcactggc atcatcctgc aggagg                                         446



      <210> 2284
      <211> 529
      <212> DNA
      <213> Homo sapiens


      <400> 2284
 ctggtcgacc cacgcgtccg cggagagcct ggacctccat cggatgccgt ctttgctcgg     60
 gaccccatga gaccccctgg gctggtgagg aatctccaag tcacagacag atcgaacacc    120
 agcatcactc tgagctgggc tgggccagac acccaggaag gggatgaagc ccaggggtat    180
 gtggtggagc tgtgcagctc aaacagtctc cagtggctcc cgtgccatgt gggcaccgtg    240
 ccagtcacca cctacacggc caaggggctt cggcctggag agggctactt cgtgcgggtg    300
 acagcagtta atgaaggagg ccagagccag cccagtgccc tggacacatt agtgcaagcc    360
 atgcctgtta ctgtctgtcc caagttcctc gtggactcca gcaccaagga cttgctgaca    420
 gtcaaggtcg gggacacagt tcgtgtgccc gtctcctttg aacatgcccg caggcccctg    480
 ggcccatcca cctgcaggag aacgtgcctg ggacggtgac ggccgagtg                529



      <210> 2285
      <211> 439
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(439)
      <223> n = a,t,c or g


      <400> 2285
 ggaacgaccc acgcgtacaa aaaccccgcg aagaggcgcc tgctggcgct gctgcatctg     60
 gctgatgtgg gcgctgacct ggacagcacc cggcggcagc ctgacacatg aagtgctggt    120
 ccccgacgtg ccccaacagc actgagtcct cctacagccg agccctctct gtgtcctgct    180
 gccagggtag ccagagcaac cgcagtgcag ccgcaggcct ggtgggcagc cccgggaccc    240
 tgtgggccag catcgcagcc agccagctgt gggccctgct gcaggcagcc cgctgaggcc    300
 ctgcgcctgg agcgctcagc gtgggtcccc tcagcctgac cagctcccac acaccccacc    360
 cggggcagca gggtcctagt ctcagctgcc acgcccccct ccctcctttg cccaggccac    420
 acccagcacc ccaccccgn                                                 439



      <210> 2286
      <211> 579
      <212> DNA
      <213> Homo sapiens


      <400> 2286
 tttcgtgact taggacgggg cgatggcggc tgagaggagc tgtgcgtgcg cgaacatgta     60
 actggtggga tctgcggcgg ctcccagatg atggtcgtcc tcctgggcgc gacgacccta    120
 gtgctcgtcg ccgtggcgcc atgggtgttg tccgcagccg caggtgagag gcggggagga    180
 gagtcttggc gcagggcggg aggtagggca cgcagctggg ctacgggggc ggcgatgctg    240
 ttgggggcga cagacgccca gtctgggaaa ccttcggtcc actttgccgc gccaaagatt    300
 aaacccgacc tgggctcgca aatcaaccag gagaaagtgg tgttctgggt cctctcttgc    360
 cgcttgcctg tggccgtgta cgggtcctcg ggagcgcccg ggtcccaccc ccgtgaaatg    420
 gcggtgccag agctttgtgt cgagtttgat tctttccggg aaactcatca gatattgtta    480
 gtgtattttg tgtgtggccc aagacagttg ttcttccagt gtggcccacg gaagccaaaa    540
 agagtggaca cccttgatgc agatgaggcc tgcagatag                           579



      <210> 2287
      <211> 410
      <212> DNA
      <213> Homo sapiens


      <400> 2287
 ctgccatagc acggagtctt cttctgactt catcctcccc ggagattacc tcctgggagg     60
 cctgtgccct ctccattctg gctgtctgca ggtcttgtag cttcaatgag catggctacc    120
 acctcttcca ggctatgcgg cttgctgttg aggagataaa caactccacg gccctgctgc    180
 ccaacatcac cctggggtac cagctgtatg atgtgtgttc tgactctgcc aatgtgtatg    240
 ccacgctgag agtgctctcc ctgccagggc aacaccacat agagctccaa ggagaccttc    300
 tccactattc ccctacggtg ctggcagtga ttgggcctga cagcaccaac cgtgctgcca    360
 ccacagccgc cctgctgagc cctttccttg tgcccatgct tttggagcag               410



      <210> 2288
      <211> 417
      <212> DNA
      <213> Homo sapiens


      <400> 2288
 gagtacccgt ccggaattcc cgggacgagc accaaccggc ttcctcaaac tcttggctga     60
 taagaacagc gaactgttta ggaaatacgc cctgttttct ccctcagacc accgagtgcc    120
 tagaatttat gtgcctctca aggactgtcc ccaggacttt gtggcacggc ctaaagatta    180
 tgccaacaca ctgttcatct gccgcattgt ggactggaag gaggactgca attttgccct    240
 ggggcagctg gctaagagtc ttgggcaggc tggtgaaatt gagcctgaaa cagaaggaat    300
 actaacagag tatggcgtgg atttctctga tttctcttca gaagttctag aatgtcttcc    360
 tcaaggcctg ccatggacaa ttccaccaga ggagttcagc aagagaaggg ttgtatt       417



      <210> 2289
      <211> 312
      <212> DNA
      <213> Homo sapiens


      <400> 2289
 atggctccgg ccgcggaccg agagggctac tggggcccca cgacctccac gctggactgg     60
 tgcgaggaga actactccgt gacctggtac atcgccgagt tctacgtggc tcatgtctgg    120
 cttcctccca acgccctcat ccttgaggga cctgacagct tccagatggg tgcggtcact    180
 gcctccttcc cggagtccag caggcaggca gcccggccca gcggaggagc tgcccaaggc    240
 ctctccctgc ccctggggga agtccctctc acgtcctttc gcgtccttct ctgcgtcgtc    300
 cgggccctct ga                                                        312



      <210> 2290
      <211> 374
      <212> DNA
      <213> Homo sapiens


      <400> 2290
 cttccgagac ctacagtgtg ccctgtacaa tggccgccct gtcctgggca cccagaagac     60
 ctaccagtgg gtgcccttcc atggggcgcc caaccagtgc gacctcaact gcctggctga    120
 ggggcacgcc ttctaccaca gcttcggccg cgtcctggac ggcaccgcct gcagcccggg    180
 tgcccagggg gtctgcgtgg ctggccgctg ccttagcgcc ggctgtgatg ggttgttggg    240
 ctcgggtgcc ctcgaggacc gctgtggccg ctgcggaggc gccaacgact cgtgcctttt    300
 cgtgcagcgc gtgtttcgtg acgccggtgc cttcgctggg tactggaacg tgaccctgat    360
 ccccgagggc gcca                                                      374



      <210> 2291
      <211> 932
      <212> DNA
      <213> Homo sapiens


      <400> 2291
 atggaaaata tggtcaccct attcagggtg gtggaagaac actgtccttg ctttcctgaa     60
 aagggaacgt tagatgtgga actatgggat cgtgttggtg taagattcca ggaactggtc    120
 ccgacaggaa attatgttcc tgtcaccgtt tggggtgatt tggccttgtg cgtgcaacca    180
 tggaatggaa gactggagga acccatggtg gccaaccatg ggcccggtcc ctctggtatg    240
 ggccatgagc cagctgagcc tgagtgcaaa aatggacaga aggcgaactg gagtcatgat    300
 gacatcaacc cctataacct gggggacact cgagaaaacc atgcaggaag ctgagaaact    360
 actggagcgt caaggccaga caaaaacccc tgattccatg ttcttggcca tggaggaaag    420
 gtccaattca agaaacaata tggaaagcag cactgctgtt cacaaacggt agtatccggg    480
 taggaacact ctctaatacc agtactgcta ctcaacacag tcttaatgtt acatttgtaa    540
 agaatatcac cactcaattt atggtttgtg gttttaatcc ttatgtcttt ttggcagcta    600
 aggcggacca gctccaggtg gtagtcagcc acaccacaac tgccagccag gaaagggtaa    660
 gggcgcaggg ctgcctgctg ccccctcagt gccagtgtcc tctgcccaga aaggtcaaat    720
 cggcagagca gggtgcggaa agcaccctga ggaaagcagg atccctagtt tccaggcttc    780
 cctgccagag agagactgga aagaccatag aaggaaagtt tctcctttca cagggggaag    840
 gatacaggga gacagcgcag aagttggaga gcagcatcga aatgtttctg gcctatgtgg    900
 cttgcaccat ccgattcccg gcagtgttat aa                                  932



      <210> 2292
      <211> 624
      <212> DNA
      <213> Homo sapiens


      <400> 2292
 ggagttaaag gtctactttg ctctttgtgc ttaagttaga tcaccgttca taatgtcata     60
 gttttctttt ttacaatctg tttcatgata ctcataaatt ttagagaaat ctgtctgaag    120
 gttctgcata cacctctgtg tgtttctggg gggtgtgtac ttttatacat cttagctctg    180
 acttgctgtt atacaaactc actcttaata tcgcatctcc ctcccctttc tctccccaca    240
 gaaacacaaa cacacttatt tatgtataga gtcctgaaag tcagaaagga cattaaaaac    300
 catgtattcc acccaactta cttggtagcc aaggaaacag aaacctatgg agaggagctg    360
 attcccctac ccccttgtag ggagcaccag gactaggccc tgggtgtcct gcttcaggtt    420
 cacagcttgg gatgcagagc ttgtccccag agcaggagct gcagggcctg ctctccaagc    480
 tgcctgcact ttctcagatg gatgtcaggt gccttccaat ctggagtacc tggaaatggg    540
 taacaatagt tgaacaagtg agtacagttg gcgaaaagct gagtctttct aaacagcttt    600
 ggaatgatta cagaggggac ttgc                                           624



      <210> 2293
      <211> 6995
      <212> DNA
      <213> Homo sapiens


      <400> 2293
 aacagacctt cctctgctag ttctacatca tccaaggctc caccaagttc tcggagaaac     60
 gttggaatgg gaaccacccg ccggcttggt tcatccaccc ttggatccaa gtcttcagct    120
 gcaaaagaag gagctggtgc tgttgatgaa gaggatttta ttaaagcatt tgatgatgta    180
 cctgtagtac agatttattc cagccgagac cttgaggaat ccataaacaa aattagggaa    240
 atattatctg atgacaagca tgattgggag cagagagtaa atgctctaaa aaagattaga    300
 tctttacttt tggctggtgc tgctgagtat gataacttct ttcaacattt gcgtcttttg    360
 gatggagcct ttaaactctc tgctaaggac ctgcggtctc aggtagtgcg ggaggcttgg    420
 tatcacgttg gggcatctgt catcagttct ggggaataag tttgaccatg gagctgaagc    480
 cattatgcca actatcttta atttaattcc aaacagtggc caaaattatg gccacatctg    540
 gtgttgtagc tgttaggtta attattcggc acacacacat ccctaggttg atacctgtca    600
 taacaagcaa ctgtacctct aaggctgtcg cagttagaag gcgctgtttt gaatttttag    660
 atttgctttt acaagaatgg cagacacatt cactagaacg acacatatca gtattagctg    720
 aaacaataaa gaagggaata catgatgctg attccgaagc aagaatagaa gccagaaaat    780
 gttactgggg tttccacagt cacttcagca gagaagcaga gcacttgtac cacaccttgg    840
 agtcctccta ccagaaagcc ctgcagtccc acctgaagaa ctcagacagc atagtgtctc    900
 tgcctcagtc agaccgctca tcttccagct ctcaagagag tctaaatcgt ccgctgtctg    960
 ccaaaagaag tcctactgga agtaccacat ctagagcttc tacagttagt accaaatctg   1020
 tgtcaacgac tgggtccctc cagcgatctc gaagtgatat tgatgtgaac gcagcagcca   1080
 gtgccaaatc caaagtctcc tcatcttcgg gcacgacgcc tttcagctct gcagcagctt   1140
 tgcctccagg gtcatacgca tccttagatg gtactaccac taaagcggag ggtcggatcc   1200
 gcacaagacg gcaaagctct gggagtgcca ccaacgtcgc ctctacacct gataatcggg   1260
 gccgcagtcg cgctaaagtg gtttcacagt cccagcgatc cagatctgct aatcctgctg   1320
 gtgctggcag ccggtcaagt tccccaggaa aattgttggg aagtggttat ggtggactta   1380
 ctgggggctc ctcacgaggc ccacctgtga caccgtcttc agaaaagcga agcaagattc   1440
 ccaggagcca gggatgtagc cgggaaacaa gtccaaaccg aataggatta gcacggagca   1500
 gccgtatccc tcgacccagc atgagtcagg ggtgcagccg cgataccagc cgtgagagca   1560
 gccgagatac aagccctgct cggggctttc ctccacttga tcggtttggg cttggccagc   1620
 caggaagaat acctggttct gtgaatgcca tgagagttct gagcacaagt acagatcttg   1680
 aagctgctgt tgctgatgct ttgaagaagc ctgtgaggag gagatatgag ccgtatggga   1740
 tgtattctga cgatgatgcc aacagtgatg cctcaagtgt ttgctctgag cgctcatatg   1800
 gctccaggaa tggtggcatt ccccattatc tgcggcagac tgaggatgta gcagaagttc   1860
 tcaaccactg tgctagttca aactggtcag aaaggaaaga agggcttctg ggcctgcaga   1920
 acttactgaa gagccaaaga acactgagtc gagttgaact gaaaaggttg tgtgagatct   1980
 tcactcggat gtttgctgac cctcatagca agagagtttt cagtatgttt ttggagactc   2040
 ttgtggattt tataataatt cataaggatg atttacaaga ctggcttttt gttcttctca   2100
 cacaatttac ttaagaaaaa tggggaggca gatttacttg gatctgtgca agcaaaagtt   2160
 caaaaggctc tagatgtcac aagggactcc tttccatttg atcaacaatt taacattttg   2220
 atgagattta ttgtggatca aactcaaact ccaaacctca aggtcaaagt tgcaatcctg   2280
 aaatacattg agtctctggc cagacagatg gatccaacag attttgtaaa ctctagtgag   2340
 acaaggcttg ctgtttctag aatcataacc tggacaacag aaccaaagag ttcagacgtg   2400
 agaaaggcag cacagattgt gctaatctct ctgtttgaat tgaatactcc tgaatttacc   2460
 atgttacttg gtgccttgcc aaaaacattc caggatggtg ccaccaaact cctgcacaac   2520
 cacctcaaga attccagtaa caccagtgtg ggctctccaa gcaatacgat tggccggacg   2580
 ccctcccgac acaccagcag caggaccagc cccctgacct cacccaccaa ctgttcccat   2640
 gggggtctgt ctccaagtcg gttatggggt tggagtgccg acgggttagc gaagcaccca   2700
 cctccctttt ctcagcctaa ctccatcccc accgctccct cccacaaggc tctcaggcgc   2760
 tcttactctc ccagcatgct ggactatgat acagagaacc tgaactctga agaaatctat   2820
 agttctctac gtggagttac agaagccatt gaaaagttta gttttcgaag ccaagaagat   2880
 ctgaatgagc caattaaacg agatggcaaa aaggagtgtg atattgtgtc ccgcgatggg   2940
 ggcgctgcct cccctgccac tgagggccgg gggggtagtg aagtagaagg aggccggaca   3000
 gctctggata acaagacctc actactcaac acccagcctc cgcgcgcctt cccggggccg   3060
 cgggcgcgag actacaaccc gtacccctac tcagatgcca tcaacaccta cgacaagacc   3120
 gccctgaaag aggctgtgtt cgatgacgac atggagcagc ttcgagacgt gcccatcgac   3180
 cattctgacc tggtggctga ccttctgaaa gagctgtcca accacaatga gcgagtggag   3240
 gaacggaagg gagccctgct ggagctgctc aagatcacgc gggaagacag ccttggtgtc   3300
 tgggaggagc acttcaagac cattctgctc ctgctgctgg agacccttgg agacaaagac   3360
 cattcaattc gagcactggc gttaagagtt ttgagggaaa ttctgagaaa tcaaccagca   3420
 agatttaaaa actacgccga gctgacgatt atgaagactc tggaagccca caaagactcc   3480
 cataaggagg tggtgagagc ggctgaggag gctgcgtcca cactggccag ttccatccac   3540
 ccggagcagt gcatcaaggt gctctgcccc atcatccaga cggccgacta ccccatcaac   3600
 cttgctgcca tcaagatgca gaccaaagtc gtcgagagga tcgcaaagga gtcattgctg   3660
 cagctccttg tcgacatcat cccaggcttg ctgcagggtt atgacaacac cgaaagtagt   3720
 gtgcgtaagg ccagcgtgtt ttgcttagtg gcaatttatt ccgtaatcgg agaagacctg   3780
 aaacctcacc ttgcacagct cacagggagc aagatgaagc tactaaactt atacataaag   3840
 agggcccaga ccaccaacag caacagcagc tcctcctccg atgtctccac gcacagctaa   3900
 tggcagtacc tgtctcttgt gtagacctag aagcaatcgg tggtgcctct cagagacctt   3960
 tccccacccc cttcatcggc tgcccagtca gtacaaggag gcccacaaat atttattaca   4020
 atcagtattt tggtcccttc cagcttttct gtagaatctt actggtattg aatgtaaagg   4080
 aagcaaggcc tgtattgcag tcttcataca aaacaaaagg aataagaaca gaaaagagcc   4140
 atactgaaac atgtcttgta cagcctgctg agatggcgaa accctgtgtg tggggtgcag   4200
 ttttttaaaa atcagagcgc tctagccact acttggtaga aagtagcatt ttttttttca   4260
 gttaataaca tatttggggg tggggggggg gtgttacttt gtgttcatcc tccttagcct   4320
 attttcttgt gcgtatggtc tgtgtggggc ccctttcaca gctggacacc acgaaagggg   4380
 atatatcttt aagttgtgtt ctgagaccta ctaaaaatgg gaatcaagtc ttggcaagaa   4440
 cagtctgaag atggcctttt aacaaacgct gggaattttg cttgtcatat ccagactgga   4500
 ggccgactgc cctggctttc agcgtagaat tgggagtgca ccctgacagt ctccttccag   4560
 ctctccctaa tcgactccac cgacaaggtc cctaccccag agcttccatg caaaggaatt   4620
 cttcaagttt aaatctggac acaaaaataa gataaatgta tggcatcatt tagggatgcc   4680
 tgagatggca gttcatgaag cacagaagat aaagaagaag tctttcatct ttactgctga   4740
 gatccttggg aacactgttg tcatgggggc tctgccaaga ccctcatctc tgggctacac   4800
 ggtgattcag attgagcacc aacttgtttc ctcccctcaa agttctgcct aagccgttca   4860
 gttctaacat ggtctcagtt aatctggtaa atggcatctt taccatctta gttctgactt   4920
 ctcagtttaa tgtgggatta agagccaaga aaagcctaga gagactggat atcacaattt   4980
 tttttaattt tataaactga agtagttcct tgaatgtctg ttgatgaaat agtcactgtt   5040
 taaggaaaaa agtaattatg aggtgtagca gattgcagaa aaacaggatt agaaacacac   5100
 ttaaaaagaa cacacattta gagtctctct tcctcctcag cgaaccacta ggcccccttt   5160
 ttaaaaacac ctttagagcc taattactcc aataaaagta actagaggtt tggagtctgg   5220
 ttaaataaat tctgagtaaa attcttaagc caaatggaaa ttcttaatgc aatcatgagg   5280
 acttctattg tctcttactg ttgtattaga tcctataaat tgaactgatt tttccataag   5340
 gaaaatgctt cttttgagat taattctaat aacgtatttg ctattgcagt gcagagccca   5400
 ctgcaactgc taggactgaa agcagaggct gggtgccaga gcacgtgatt cttaacatca   5460
 tttccacaga cccctctgcc ctgaccctct gcattggatg caggaagctg ggaaagactg   5520
 atgttgattt ggaaacatgg gctgaaaatg aaggccccat agtgcatagg aacagtaaag   5580
 ccagggtgct gacgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg gggtgttgtg   5640
 tgtgtttgcg cgtgcaccct acacatgtgt ggtacctcac tgctgctgtt tagggaactt   5700
 gagggacgcg tttcaagggg ttgggtatta ctgacgagct ttggctcaaa atatagcagg   5760
 accaggtctt ttgttgataa gtactgtttg tttattaata tgtcattaat ggtatttctt   5820
 ttttacactc tacaagtgaa ttagggagtc tcttgttgac ccctttgttg caggaatggg   5880
 cgtcgggcta ggttatccat gagtttcttt attcctaatg cagttagaaa gacctttctc   5940
 cttgagctct ttgactccca gaaggtaccc cagtccccag tgtacttaga aaggatctcg   6000
 aacattgctg gacgtcctca tagtactcac aaagggctag ccttgaatgt cactcgccca   6060
 gtcttcagtc tcctgactta gagatacaat cacgtcacag gtctcttggc ctcaatctga   6120
 aaactgctgc cgccgcgccg aggagactcg catgccgcca ccacctcact gggagggcgc   6180
 cgagcccacc gtcgccccct agaccctgac agctgcagct gccttgcctt gccgccgcct   6240
 ccctgcaggg cccctgttcc aatgaaaaac agaacacaaa agagcagagc acctaagcct   6300
 gtctctgcct ccctgtctac ctgactggcc agggcccaag acccccgctg ctccactgcg   6360
 gggctgggcg ggctgactcc ctgcttcctc caagctgctg cctcccctgc agccagggtc   6420
 tgggcagggt gcagccggtc ctcggggcac gcagcttcct tcaagtacac tgtgtgtgct   6480
 tcccggacct gcggcgatgc cacgggcctg ccttttctat gcgcctcact agcttaccac   6540
 cctgtgcagg taatgcaact gactttgtct catcagtctt tttctttccc tgccaccctt   6600
 tatttatcaa gcgtaatgtt acactttaaa ggacagcaaa taagaacttt gtagaatccc   6660
 accaggactt tgctaacaat aatgtttgga aataaagaag tgctctgaaa aaatatcagc   6720
 caccaaaata gttatgttgg cactgtgttc acacgcatgg tccccacacc cccaggttgg   6780
 gtgggttttt ttgttttttg ggtttttttg gggggggggc tttttcatgt tacatccata   6840
 tctgtattta tatcttattt gtttcacttt caagggtatc atggcaaatg tacagatttt   6900
 tttgttaata atgtgctagg atttgctaaa aaagaaaaaa aaaaaaccct tttgagtttg   6960
 ccctaaaata aatgagactt aattcaaaaa aaaaa                              6995



      <210> 2294
      <211> 1224
      <212> DNA
      <213> Homo sapiens


      <400> 2294
 tcaatggctt attagatagg cctctccaga ccccttccca agaggaggag tcgggttggg     60
 ggacctgtgt ctgttctctt cccggtgctt tgtgtcttcc aggcttgaaa gcatcccggt    120
 gatggtgctg ccatcatttc ccttgggggt agagggtctt ttctgaaagt gtttgttcac    180
 ccgttcggaa cctagaattc ctttggcgct ttgcctttcc gctcgctcca gccgggcgct    240
 gcccaccagg tgtcccactg cagacctctc cccgcgacac cgacgcccac cgcagctcgc    300
 cccttccccc cgcgcgcgca agccctggcc aggtggccgc ggcttaccgg tgggcgcgct    360
 gtccaggatg cggaggtcgt aagccccgga gcagcggtag ttggcagctg tgccgttgtc    420
 ccacactacc accacctcct cggggctctc gaagctccgg acggtgccca catggccctc    480
 gccgccgtcc tgcttccccc acttccagtc cgggccgcgc actacccgag cgccaacccc    540
 ttccaccatc acccggttat tccgggagtt actcatcggg gcccgggcgg taggggctct    600
 cgccgctgca cgccgccgct cgccgccgct gccgccgggg ggcccgtgag ggagttgggc    660
 ccgggccgga cttggaagca tcgcttcagc ccattctcca tgtcctcttt gtagaagttt    720
 aattcgttcc aggtcataac aaacttgtac aagatcaccc acttgaaact gcgaggtgcc    780
 tccttctgca ccctgagcag catctccact tcggacaatg ttcgctttag tgagaacagc    840
 aggattgaag gtccacctat tgccacttgg atactgtact acaatgtcat gatcttcatc    900
 aatgccacaa acagttccag ttgtagttaa agtctcaaac attccatcag tccatcctcc    960
 atgaccatgc tgcaaagact gtacaatttc gaggtcgaga tctatattta ccaggtcacc   1020
 aatctgcaat ccaccaggat tcctgttgcc attctgctca cctagcacag ggcagtgatc   1080
 tctgtagaaa gaacctccct tggcatcctg gacacatttc agatcagacg tgcttttgtt   1140
 gttctctgtc tcaatgaatg gctctaccct ttcacttggt tgcccaagcc agaaagctgt   1200
 aattgcactg gtccaggtca ccat                                          1224



      <210> 2295
      <211> 999
      <212> DNA
      <213> Homo sapiens


      <400> 2295
 atgaagatcc attcctgtgc ttttgtgatt gaacaagagg agaaaaagaa aacagaagct     60
 cataaagaag gagatggagt gaagagggct gataagattc tgggggttac caaagatcct    120
 ggaaccattg ctggtctcaa tgtagttaga attatcaatg agccaactgc tgcttctatt    180
 gcttatggca cagacaaaaa gtttggagct gaaagacatg tgctcatcta tgacttaaga    240
 gatgaaattt ttgatgtgtc tgtccttact cttgaggatg aaatctttga gatcaaatct    300
 acagctggag acacccactt aggtgaagaa gattttgaca accaaatgat caaccatttt    360
 attgctgagt tcaaatacaa gcataaggac agtagagcag atatttatac ctccattacc    420
 catgcccaat ttgaagaact gaatgctgtc ctgttccgtg gcacccagga ccccatagag    480
 atagcccttc aggacaccaa actagacaag ttgcagatcc atgttattgt cctgacccag    540
 accttcacta cctaccctga caaccaacct gatgtcctca ttcaagttta tgaaggtgag    600
 agtgccataa ccaaggataa caatttgctt gttatccagg gcaagtttga gctcacaggc    660
 atacttcctg ctccctttgc tgttcctcaa attaaagtca cttgtgatat tgatgtcaat    720
 agcagcctca atatctctgc tgtaggtaag agtacagaaa aagagaacaa aattatcatc    780
 actaatgacc aggggcattt gagcaaggaa gacattgaga atatggtcca ggaagctgag    840
 tacaaagctg aagatgagaa gcagaagaac aaggtggcat caaagaattc acttgactct    900
 tatgcattca acatgaaagc aactgagaaa cttcaaggca agatcaacaa taaggataaa    960
 cagaagatac ttgacaagtg taataaaatc atcaactga                           999



      <210> 2296
      <211> 2269
      <212> DNA
      <213> Homo sapiens


      <400> 2296
 gagagagcta gcaccatgag cttcaaaccc tgttccttca gttcccgggt acacactttg     60
 tcccaggcct gaattccacc cccgagctcc ccttcctcac cggccgctgc ccctcgggct    120
 cagctgggga aggacgccct gagtcccttg gccctactcc tccgcccacg gcgcgcatat    180
 ccccgccccc tcccaacttc agaaagtttg gcctggggct ccccacctcc gagcaggttc    240
 gggcccagcc ccgcctccca gccccgctcg ccgcgcctgt ccttccttgt actgggagtg    300
 gcctgcagtg ccatcctcat gtacatattc tgcactgatt gctggctcat cgctgtgctc    360
 tacttcactt ggctggtgtt tgactggaac acacccaaga aaggtggcag gaggtcacag    420
 tgggtccgaa actgggctgt gtggcgctac tttcgagact actttcccat ccagctggtg    480
 aagacacaca acctgctgac caccaggaac tatatctttg gataccaccc ccatggtatc    540
 atgggcctgg gtgccttctg caacttcagc acagaggcca cagaagtgag caagaagttc    600
 ccaggcatac ggccttacct ggctacactg gcaggcaact tccgaatgcc tgtgttgagg    660
 gagtacctga tgtctggagg tatctgccct gtcagccggg acaccataga ctatttgctt    720
 tcaaagaatg ggagtggcaa tgctatcatc atcgtggtcg ggggtgcggc tgagtctctg    780
 agctccatgc ctggcaagaa tgcagtcacc ctgcggaacc gcaagggctt tgtgaaactg    840
 gccctgcgtc atggagctga cctggttccc atctactcct ttggagagaa tgaagtgtac    900
 aagcaggtga tcttcgagga gggctcctgg ggccgatggg tccagaagaa gttccagaaa    960
 tacattggtt tcgccccatg catcttccat ggtcgaggcc tcttctcctc cgacacctgg   1020
 gggctggtgc cctactccaa gcccatcacc actgttgtgg gagagcccat caccatcccc   1080
 aagctggagc acccaaccca gcaagacatc gacctgtacc acaccatgta catggaggcc   1140
 ctggtgaagc tcttcgacaa gcacaagacc aagttcggcc tcccggagac tgaggtcctg   1200
 gaggtgaact gagccagcct tcggggccaa ttccctggag gaaccagctg caaatcactt   1260
 ttttgctctg taaatttgga agtgtcatgg gtgtctgtgg gttatttaaa agaaattata   1320
 acaattttgc taaaccatta caatgttagg tcttttttaa gaaggaaaaa gtcagtattt   1380
 caagttcttt cacttccagc ttgccctgtt ctaggtggtg gctaaatctg ggcctaatct   1440
 gggtggctca gctaacctct cttcttccct tcctgaagtg acaaaggaaa ctcagtcttc   1500
 ttggggaaga aggattgcca ttagtgactt ggaccagtta gatgattcac tttttgcccc   1560
 tagggatgag aggcgaaagc cacttctcat acaagcccct ttattgccac taccccacgc   1620
 tcgtctagtc ctgaaactgc aggaccagtt tctctgccaa ggggaggagt tggagagcac   1680
 agttgccccg ttgtgtgagg gcagtagtag gcatctggaa tgctccagtt tgatctccct   1740
 tctgccaccc ctacctcacc cctagtcact catatcggag cctggactgg cctccaggat   1800
 gaggatgggg gtggcaatga caccctgcag gggaaaggac tgccccccat gcaccattgc   1860
 agggaggatg ccgccaccat gagctaggtg gagtaactgg tttttcttgg gtggctgatg   1920
 acatggatgc agcacagact cagccttggc ctggagcaca tgcttactgg tggcctcagt   1980
 ttaccttccc cagatcctag attctggatg tgaggaagag atccctcttc agaaggggcc   2040
 tggccttctg agcagcagat tagttccaaa gcaggtggcc cccgaaccca agcctcactt   2100
 ttctgtgcct tcctgagggg gttgggccgg ggaggaaacc caaccctctc ctgtgtgttc   2160
 tgttatctct tgatgagatc attgcaccat gtcagacttt tgtatatgcc ttgaaaataa   2220
 atgaaagtga gaatcctcaa aaaaaaaaag ggggggccct ttttaaggt               2269



      <210> 2297
      <211> 387
      <212> DNA
      <213> Homo sapiens


      <400> 2297
 cccacgcgtc cgctttttgt tcatataata atagactagt aagaaaatca ctccttgaaa     60
 actgtgagat catagccttt tcctatcata acaaattacg cttatgcatg cctactgcat    120
 tagaacatcc caacacagct gttctgtctt tggcatcctt aattcctgta ggagctgtct    180
 catcagctgt ggccagtgtc gttctgggac catacaccaa aacagtgatg ttttaacagc    240
 attatagact tgttctggca tcagatttcc atcagcgatg accttggcaa attcatcagt    300
 gaattgctct gctccttcat ggtcagcaga tgctttctca ctgtataaat ctttaaaaca    360
 aattgaattc catgtttaag tttctac                                        387



      <210> 2298
      <211> 401
      <212> DNA
      <213> Homo sapiens


      <400> 2298
 gagggtgaca cagaaagttt ctcaccaggg agtcgaggca gtgggcgaaa caagggatgg     60
 gggaacagcc ctcacccttg gccgcctgct ccaggctggg gcagctgctc gataccagga    120
 agcctgccag caggaagcta cggcccagcc acaggctggc ctgctccagc atctgcagct    180
 gccagtcctc cgcggctccc tccaggggca ggcctcgcat ccagagcaag gttcccagca    240
 tcagcccttg gaactccaac caagctctat ccaaatgcaa acgagggcag ctgggggaaa    300
 tcactcagga gcctacatgc tttgtctgag gcactacccc tagaatctcc agctttcaaa    360
 agtggcatgg acagggaagt tgttttcctt tttaagaagg a                        401



      <210> 2299
      <211> 2078
      <212> DNA
      <213> Homo sapiens


      <400> 2299
 cggcccatta attgaccttt gcaaagggcc acatgaaaca cacactggaa agattaaaac     60
 catccaaatt tttacgaatt cctcaacata ttgggagggc aatccggaaa tggaaacatt    120
 gcagaggatc tatggaatat cctttcctga taacaagatg atgagagact gggaaaagtt    180
 ccaagaggaa gcaaagaacc gagatcacag gaagatcggg aaggaacaag aacttttctt    240
 tttccacgat ttgagtcctg gaagctgttt tttccttccc agaggagcct tcatttataa    300
 tacgcttaca gatttcatac gagaggaata tcacaaacgg gacttcacgg aggtgctctc    360
 tcccaatatg tacaacagta aactctggga agcctcaggc cactggcagc attacagcga    420
 gaacatgttt acctttgaga ttgaaaagga cacttttgcc ctcaaaccca tgaattgtcc    480
 agggcactgt ctaatgtttg cccatcgtcc acgatcttgg agggaaatgc ctattagatt    540
 tgctgatttt ggagttctgc atagaaatga actgtcgggg actctcagcg gcttgaccag    600
 agtgaggcgc ttccagcagg acgatgctca cattttttgc acagtggagc agattgaaga    660
 agaaataaag gggtgtttgc agtttttgca atctgtttac tcaacatttg gcttctcctt    720
 tcaattaaac ctgtcaacaa ggccggaaaa cttcctagga gagattgaga tgtggaatga    780
 ggctgagaag caactgcaga acagcttgat ggactttgga gaaccgtgga aaatgaaccc    840
 aggagatgga gcattttatg gccctaaaat tgacataaaa atcaaggatg ctattggcag    900
 ataccatcaa tgtgctacaa ttcagctgga cttccaactg cctattagat ttaatctcac    960
 atatgttagt aaggatgggg atgataagaa gagacctgtg atcattcatc gagccatttt   1020
 gggatcagtg gaaagaatga tagccattct ttcagaaaac tatggcggaa aatggccttt   1080
 ctggctatct cctcgtcagg tgatggtcat ccctgtgggg ccaacttgtg aaaaatatgc   1140
 acttcaggta tccagtgaat tttttgaaga aggatttatg gctgacgttg acttggatca   1200
 cagttgtaca ctaaataaga aaatacgaaa tgcacagctg gctcagtata attttatttt   1260
 ggtggttgga gaaaaggaaa agatagataa tgctgtaaac gtgcgaacaa gagacaacaa   1320
 aattcatgga gagattttag taacttctgc cattgataaa ctgaagaatc tcaggaagac   1380
 acggacactc aatgctgagg aggccttttg aagtccttcc ctgatatttg cttctgtgta   1440
 actttgtttt gacccttaaa aatgtatttt tcttaacatg ttagtacttc tacgactttg   1500
 gagccactga tgggtccact catggcctca gctgagaaag gagacgatga acgtgtagct   1560
 gacatgcacg aagtttaatt tactcatgtc cacgggggac gtttagaggg cacgtgggaa   1620
 attttccagc aatcaatgcc ttgagaaact taaatgggga aatattattc atcgagaaag   1680
 tgaaacaaaa cactaggaaa tgattatgaa atgttagtga ttttccaaaa gatgggcctt   1740
 caaataaaag tctgccagag ttttttttaa aataggaggg aaaatcctta ttttcctaat   1800
 atgtcctcag gtatttttat gaccttccta cctaaaattc cacacctgaa actttatctt   1860
 cctaaactgg aatccattac cttaatttta actaaccaac aaccacaaaa gcgagcagct   1920
 actgcctaaa tattggatta ctgacaaagg aattcagttt tgtggaatct ggtgtttgca   1980
 ctataggtta agagttgcca tttaaatgtt tcttattcat aattaggttt tgttccgctt   2040
 tagaaaaaaa taaattccca aatgaattgc aaaaaaaa                           2078



      <210> 2300
      <211> 496
      <212> DNA
      <213> Homo sapiens


      <400> 2300
 aatacagccc tggtctaaat gaaatcgaag agttcttatt aattattcat aatgccatga     60
 atatgttacc ttatttttta taattgccag tctgtataat taacctttca tttggttaaa    120
 gtacttaaca ttaagtagag ctataattac aactgttttt aaaagtatat ggaagaatgt    180
 ttaaatgttt aattagaacc acttttttta gcttcataaa gaattttttt tacttgtcaa    240
 caaggatctt taattattta aaccaaaaga gcagaacaga ccagaaaaga aaaacaacta    300
 gtcaagctgg gaactgcaat ggtggcgtcg ttccgtgagt ctcgggtttt gcttcttggg    360
 cttgtggtca gagtccttac ctttgatttc ctaacacagg ttgttagagt tggaagtgag    420
 tgtggagatg agttagtccg actttattct ttcacggatg agaaagcgaa ttatcttcag    480
 caaggtgggt gcaggg                                                    496



      <210> 2301
      <211> 1255
      <212> DNA
      <213> Homo sapiens


      <400> 2301
 gtgtacttat ttgaaccatt gactgcgatc aatttatacc actcactatc gagaatctgt     60
 ccctaaagcc ccaattcgcc acaatctgga acaattgctt gagcggacgc acgcttaatc    120
 cctttagtgc gggttaatgc ccaacttgac gctgtccccc tgtgaacaac cttctcactg    180
 gtaaaacgct cccccactga gcacctcatg acccccgccc ctgcttgccg gagaacaacc    240
 cctttgactg taattttcca ctacctaccc aactcctata aaatggcccc acccctatgt    300
 ccctttgctg actctttttg gactcagcct gcctgcaccc aggtgaaata aacagcttta    360
 ttgctcacac aaagcctgtt tggtggtctc ttcacacgga cgcgcatgaa atttggtgtc    420
 gaaacatttg gtgccgtgac tcggatcggg ggacctccct tgggagatca atcccctgtc    480
 ctcctgctct ttgctccgtg agaaagatcc acctacgacc tcaggtcctc agaccgacca    540
 gcccaagaaa catctcacca atttcaaatc cggagcttgc tacatgtgcc ggaaatctgg    600
 ccactgggcc aaggaacgcc cgcagcccgg gattcctcct aagccgcgtc ccatctgtgt    660
 gggaccccac tgaaaatcgg actgttcaac tcacctggca gccactccca gagcccctgg    720
 aactctggcc caaggctctc tgactgactc cttcccagat cttctcggct tagcggctga    780
 agactgacac tgcccgatcg ccttggaagc cctatagacc atcacggatg ccgagcttcg    840
 ggtaactctc acagtggaag gtaagcccgt ccccttctta atcaatacgg aggctaccca    900
 ctccacatta ccttcttttc aagggcctgt ttcccttgcc tccataactg ttgtgggtat    960
 tgacgggcca ggctttctaa acctcttaaa actccccaac gtctggtgcc aacattagac   1020
 aatacgtcgt tttaagcact cctttttagt tatccccatc gtgccaggtt cccttattag   1080
 gctgaggaca ctttaactaa attatctgct tccctgacta ttcctggact acagctgtat   1140
 ctcattgcca cccttcttcc caatccaaag cctcctttgt gtcctcctct tgtatacccc   1200
 aacttaaccc acaagtataa gatatctcta ctccctcctt gacgaccgat tcatg        1255



      <210> 2302
      <211> 467
      <212> DNA
      <213> Homo sapiens


      <400> 2302
 atttcctgga atcctcttgc acctcccaaa tggctcacgg ttccagagcg catgtcttcc     60
 ttcagggtga ggtggcaaat agagtgcaat ggagatacct gctaccaccc aggatgccca    120
 aacggccact ggaagatgtc cttgggctgg cccaggatgc ccaaacggcc accagtatcc    180
 aactgaagac agctctccca gctgaagaca gctcccctcc atgtgatgat tcagaaaccc    240
 aggctccttc cgactcctgg ctgcactgtt ccttagggtc ttgggcctca tgattatctg    300
 tattcaatac tcagcattga gagaagctgc tgctgctaat gctgctgctg ctgctgccgc    360
 cgccgccgct gctgctgctg ctgttggtct gaggctgcag taggtttctg tgcagcattg    420
 cagaatccac accctctggg gctttgcggc gcttaagagg cggccgc                  467



      <210> 2303
      <211> 864
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(864)
      <223> n = a,t,c or g


      <400> 2303
 ttagganggg cagggagtcg tgtggaaggg ccactgcagc ccggtgcctg gcaattagta     60
 ggtgctcagg aaatgtggtt cttgagcctc tgcccttctc tttgttgttg gttttgcaga    120
 gtcattaagg gagtttactg cagactgtcc cccatataag tgtcctgtgg cccctgagcc    180
 tttgcctcag cctctctctc tccctgcagt gccctgggga ggaatcaact gacagccctt    240
 tcagtcttcc cacagtccag ccagttaaat caaggtgttc cccttttata gaggagtctc    300
 ctagagccaa ccgcagcatc cctgcctttg ggagccacct ggaatgtgcc agctgcagta    360
 gccgttcctt ccacggcccc cccccatgct gtctgtgggg cttgccactg agtgctccat    420
 ctccccatgt gctccatccc ccggcatctg ctgccattgg tcctgcctgt tgcgttactt    480
 ctctgtgccc tggagcccct caagcacaga ggcctcgaaa ggttgatcag acatcctcag    540
 cacctggagc ggggcctggc acacaagacg gcaatgaacg gcccaacccc tagaagttca    600
 ccccccacaa gaccctgcag ggcgggggct gagtgtccca agaagcctct tgggaaggga    660
 tggtcttaga ccctagtggt gtcttcccat tctgcagagg cctagggatg tccccaggtc    720
 cccagagtgg gaggggaagg gtcagaagtc catggaaata aaacacaggg ccagctacaa    780
 aatttgtggg gcccagtgca aaatgaagat gcaagttccc ttgttcaaaa agcagtaaaa    840
 aaaaaaacac aaaagttttt tcaa                                           864



      <210> 2304
      <211> 3733
      <212> DNA
      <213> Homo sapiens


      <400> 2304
 gatattggaa agaaaggccc acccagaagg tgataccaag agccacggaa aatcatggac     60
 tcaaaagcta cctccagaaa acaaaactga gtattgatga agcagctttc ctactcccag    120
 acaccaatct caagtctgag cttctggaac ttctgaccca ctggcttcaa gttggggttc    180
 ccatgacccc ctctttgggt tcgattaatt tgctgggatg gctcacagaa ctcagggaaa    240
 cacatacgta catttgctgg tttattgtaa aggagactac aagggataca gatgaagaga    300
 tgtgtaggac agagccagct ctggcctgct ctatctctca ttactgtgat gacggctgta    360
 tccagatgct aaacactcca gagacactcc aatgcagtgc taaagactca aaacacttca    420
 tccccaaaga atgtagcatt ccaggagaaa acaggcctcc ttctgacact ggtaaaactg    480
 tgaagtttct ttccctgaat attttcaatc tgcagttggc tgaatccaca gatgcagaac    540
 agagagctaa ctgcattttg cggtgcttct taactgagac gacgctaaac taccagaaga    600
 tccttagtgt ccgtccagga accaaactcg cgaccgcctc gcacgtgtca ggcctaggac    660
 tacagacacc acctttcggc cttgctcagc acctcatccg cccccacgcc ttccttgcgc    720
 ccaaagaccc cctcacctcc tttacagaga gaaattcaag aagcggaaag actagatgcc    780
 gatccaaaaa gtgcgcgatg cgagtagtca agtcgtactc cgccatcttg ccaaagaaaa    840
 gggagtctgt gctcactaaa actttattgg tagcgccgac aaacgaacag acagatcctg    900
 tactgcgcat gtgctgtggt aaaactggcc taaagaaagg ggcggggttt accctggaga    960
 gcagaggaca acgacgcatg cgcgcgggtt gtcccaccct ttgcgttagg gcgcgagtga   1020
 cggaaacaga tccctctatt tgtagtgagg tcacgttttc ctggatgatc ttgatgctta   1080
 tggatgtttg tcagtgtctg ggcattgaag agtttggcat ttattgtagt cttcgcagtc   1140
 tggacctgtt tgtgcccatc tttcttgaga aggttttcca ggtatttgaa gggacttcaa   1200
 gcccaataat gctgtggttt ttgcagactc atagaggtac caccttggtg gccttggata   1260
 agatccagaa gaattctctg gattatcagg cagaaactct tgttcttttc ccttactttc   1320
 tcccaaacaa atggaatctc tctgtctttg ctgagccacc tggaactggg gatgtggtga   1380
 tgcaagcacc cctgtggcca ccaccactgg gactgtactg ggccctggaa cactatgatc   1440
 agcatgtggc aaagccagcc aggcaaagga gcctctccct ctggccacca ccaccaacag   1500
 cccacaaggg gtttttgcaa ggccactgcc aatgttcact caaaacccaa aggctcttca   1560
 gtcagcttat ggcgaatgct gccaggcctg agactcaggc ttcagggcag tggactcctt   1620
 tcagcccagg gcagatccag aaatgctctc caagatccag aaatgctctc gggaccccaa   1680
 gagcctgctt gttgctctac cctactgtgg ccgagctggg tagcactgag ttcaatgtaa   1740
 agccttccat ttgctgcact ctcccttacc aaggtgcaca gtcccccagt ctccacaccc   1800
 tacaactgcg ggggaatggg gttggggggc agcatcagca attcaagact gtctctctgg   1860
 atcccttcaa tgcctctttt agagacatga agctaaaact aggtaaatca gggatttctt   1920
 cttggtttgt atccattgct gctgctgtgg gggatgaagg tttggttccc aggtcaatgg   1980
 agttatattc ccagaaagct tatgactgcc tctgctgtgt catgcaggtt gtcaggaaag   2040
 taggggaaag ctggcagtca cagacctcgc ccagctccca cacaacccaa aaggccaatc   2100
 ttacttccac cctgcccccc acaacagcac tgagtgtgtt tccagggagt ggataccagg   2160
 agtggggcac tgctgtaaag atacttgaaa gtatggaagc gactttggag caggacaaca   2220
 agacgaggtt ggaacagttt ggagggttca gaagaaaaga agacagaaag atgtgggaaa   2280
 gtttggaact tcctagagac ttgtggaatg attttgacca aaatgctgat agtgatatgg   2340
 acaatgaagt ccaggctgag gtggtctcag atggagataa ggaacttgtt agaaactgga   2400
 gtaaagtgtg gaagggaaat gtggggctgg agccccgata cagagtcccc actggggcac   2460
 tgactagcag agttgtgaga agaggtccac catccttcag acctcagaaa tgtagatcca   2520
 ctgacagctt gcaccatgaa cctggaaaag ctgcaggcac tcaatgccag cctgtgaagg   2580
 atctgcccaa ggctgtggga gcccactcct tgcatcagcc agccctggat tttaggcagg   2640
 aatatttaaa tcccttttcc aaaaatgcaa aattccagta cgaatgtggg aattattcag   2700
 gagcagcaga aaatttttat ttttttaaag ggttggttcc agcaacagat agaaatgctt   2760
 taagttcact ctggggaaag ctggcctctg aaatcttaat gcagaattgg gatgcagcca   2820
 tggaagacct tacacggtta aaagagacca tagataataa tgatgaaaaa cctagcttca   2880
 cacatgtagt tggaaaagaa agatatctta atgcaattca gacaatgtgt ccacaattct   2940
 ttcgctattt tgacttacag cagttcataa caaacaaggg attgttcgaa aacgtcggcc   3000
 aagggtctaa aagatctagt taagttttat caaacaggag ttcttacaca tataaaagac   3060
 ccaatttaca gaatttgttg gaatgtttaa tatgttaact ttgactttga tgggggctcc   3120
 agaaaaagct gaggggaatg tgaaccaggg cttgtgaaat gacttcttcc ttggtggcta   3180
 gtcctgaggg tttcaatgaa aaatgccccg tctcttcata tttgagactt ttctgtcgca   3240
 tcccacccag tgtatcagcc attaaccatg ttggcagatt aaattgaaca tgactccaga   3300
 agaagctgaa agggtggatt ggtaaaattt gattaggaaa tggcaagcct ggatgcccca   3360
 agatttgatt cctaaattag ggtcatgtgg gttatggggt aacaatgcag ttctcacccc   3420
 ttcagcaagt gattgaaaag acccaaaagc ctttccttta gaagcccaga tgttggccca   3480
 tgaataatga gaaagaacct aaatcagaat agcaggtcag aaggctccct aacgggggca   3540
 actccaagat tctgggcttc tactgaagaa ccataaagaa aagatgaaaa aaaaaaacta   3600
 tcaaagaaag atgaaataat agatctatta tataaagcgg tcactcacac ttttggaaac   3660
 acacatatta cggtataaat tttgaagaat tggaataaaa ttgattcatt ttaaaaaaaa   3720
 aaaaaaaaag gtt                                                      3733



      <210> 2305
      <211> 3093
      <212> DNA
      <213> Homo sapiens


      <400> 2305
 atgcacaagg agctgcctgc gttggctgcc tgtggtcttg ttgctgactt tgaccccgtg     60
 ggggaggagg aaactgcaga ctttggccca ttggtgctag attcagacag tgacgattcc    120
 gtggaccggg acattgagga ggccatccag gagtacctga aggtgggatc cagcaaggac    180
 cagggctctg cctccccagt cagcatgagc agagcagact cctttgagca gagcatcagg    240
 gcagaaatag aacagtttct gaatgagaaa agacagcatg agacccaaaa atgtgatggg    300
 tcagtggaga agaaaccaga cacacatgaa aattcggcga agtcactctc gaaatcccac    360
 caagagccgg ctacaaaggt ggtgcaccgg cagggcctga tgggcgtcca gaaggagttc    420
 gccttctgca gacctccccc ggttagcaaa gacaaacgtg cagcccagaa gcctcaggtc    480
 caaggtcacg accacgacca cgcaggagaa ggagggcagc acaaagccag caacccccac    540
 cgcccttcag aagcagtaca gaataaaagt gggattaaaa ggagcgccag caccgcaagg    600
 aggggaaagc gagtcacgag cgccgtacag gctcccgagg cgtccgactc cagcagcgac    660
 gacggcattg aggaggccat ccagctgtac caggtgcaga aaacacacaa ggaggccgac    720
 ggggacccgc cccagagggt ccagctccaa gaggaaagag cacctgcccc tcccgcacac    780
 agcacaagca gcgccacaaa aagtgccttg ccagagaccc acaggaaaac acccagcaag    840
 aagaagccag tgcccaccaa gaccacggac cctggtccag gggatctgga cgctgaccat    900
 tcccccaaga tcccaaagga aaccaaagct ccacctccaa cgagcccggc ttccaggagc    960
 aagtttgtgg aatggtcctc ttgccaggca gacacctccg ctgagctgat aagcagtcct   1020
 ggacattttc aagacgatcc tgccggccct atggagggca gcgatgggtc cctgtccgca   1080
 agcccactct tctactcccc caacgtgcct tcccgctctg atggtgacag tagctccgtg   1140
 gacagcgacg acagcattga gcaggaaatc tggacgtttt tggccctcaa gggcacagcc   1200
 agcgaggccc cgggaggaga gggcgccgct agggtgcccg gtgacactcg cacgtcacag   1260
 ggccagggta agacagacga ggcaaggcac ctagacaaga agaagagctc cgaagacaaa   1320
 agcagttccc tggacagtga caaggacctg gacacagcca tcaaggactt gttaagagag   1380
 tcccagggcc cagctcccag ccctggctcc ttgtctgaca acagcagttc agtggacagc   1440
 gacgatagca tcgaactgga gattaggaag tttttggtgg aaaaggccaa ggagtcggga   1500
 gtcccaggcc aggcccagcc ctgtctttgg aagcccacac ttgctggcga agaaggactg   1560
 cgatcaccgg ccaagcagga aggtgcctgg tgctacgact cccaggaccc caagtgtggt   1620
 gacttgaaga agccttccaa aaagcgtgtg aaaaggaagc cctactctac taccaaggtg   1680
 acttcaggga gcacattcaa tgagaataca agaagatatg ctgtgcacac caaccagtgt   1740
 aggagacctc atggctcccg ggtaaagaag aagaggtacc cacaagaaga tgacttccat   1800
 catacagtct tcagcaacct tgaaagattg gacaagcttc agcccactct tgaagcctct   1860
 gaggagtctc tagttcacaa ggacagagga gatggagaga ggccagtcaa cgtgagggtg   1920
 gtgcaggtgg cccctctgag gcttgaatct agtaagtata ctggaatcac ttgccaagaa   1980
 aacaatctgg atgccaagaa agctccccat gaggacaccg tacacgacat cactaacgag   2040
 gacgccacac acgacatcgc taacgaggat actgtacacg acatcgctaa cgaggccgcc   2100
 gacaagggca tcgccaacga ggacgccgcc cacggcatcg ccagcgagga cgccgcccac   2160
 ggcatcgcca gcgaggacgc cgcccagggc atcgccagcg aggacgccgc ccagggcatc   2220
 gccagcgagg acgccgccca gggcatcgcc aaggaggacg ccgcccaggg catcgccaac   2280
 gaggacgccg cccagggcat cgccaacgag ggcgccgccc agggcatcgc caaggaggac   2340
 gccgcccagg gcatcgccaa agagggcgcc gcccacggca tcgccaacga ggacgccgcc   2400
 cagggcatcg ccaacgagga ctccgcccac ggaatcgcca gcgaggacgc cgcccacggc   2460
 atcgccatcg ctaatgagga tgccatatat gacatcgcta atgacaccgt acaaggcacg   2520
 ctaacgagga cgctgtacac gacatcgcta atgaggacac catacaaggc attggtaatg   2580
 aggacgttgt atatgacatc gctaacaagg acactctaca agccgtcgct aacaaggaca   2640
 ctgtacacaa catcgctaat gacggcaccg tacaagacat caccaatgag ggcgctttat   2700
 acgacattgc taatgatacc gacaaggcac gctaacgcgg acactgtaca cgacatcgct   2760
 aatgaggact ccgtatacga catcgctaat gagggtgccg tatatgacat cgctaatgac   2820
 accgtacaag gcacgctaac gaggacgctg tacacgacat cgctaatgag gacaccatac   2880
 aaggcatcgg taatgaggac gctgtatacg acatcgctaa cgaggacacc atacaagccg   2940
 tcgctaacaa ggacactgta cacaacatcg ctaatgacgg caccgtacaa gacatcacca   3000
 atgagggcgc tttatacgac attgctaatg ataccgacaa ggcacgctaa cgtggacgct   3060
 gtacacgaca ttgctaatga ggacaccgta taa                                3093



      <210> 2306
      <211> 1029
      <212> DNA
      <213> Homo sapiens


      <400> 2306
 atgaccttgg gccctctgac caaccagcgc aaggaacatc tcaccaattt caaatcagtc     60
 tccaccccaa gttctgagtc ctttgaatgc ttcttttcta cggactcatc tgacctctcc    120
 ccttctcctc aagctgctcg tcgccaggcc gagccaggag cttgctttaa gtgctggaaa    180
 tctggccact gggctgagga atgcctgcag cccaggattc ctcctaagct gcatcccatc    240
 tgtgtgggac cccactggaa atcggactgt ccagctcacc tggcagccac tcccagagcc    300
 gctggaactc tggcccaagg ctctctgact ccttcccaga tcttcttggc tgagtggctg    360
 aagactgaca ctgcccgatc gcctcagaag cctcctggac cgtcacagac actttgggta    420
 actcttacag tggaggtggc tgccactgct ttaatacttt tagaggccct caaaatcaca    480
 agctatgctc cacttactct ctacagttcc cataactttc aaaatctatt ttcttcctca    540
 cacttaacgc atatactttc tgcccccaag acccttcagc tatactcact ctttgttgag    600
 tcttccacaa tcaccattgt tgctggccca gacttcaatc cggcctccca cattattcct    660
 gataccacac ctgaccccca tgactgtatc tctctgatcc acctgacatt cattccattt    720
 ccccatattt ccttctttcc tgttcctcac cctgatcaca cttggtttat tgatggcagt    780
 tccaccaggc ctaatcgcca cacaccagca aaggcaggct atgctatagt atcttccaca    840
 tttatcattg aggctactgc cctgcccccc tccactacct ctcagcaagc caaactcatt    900
 gccttaactc aggccctcac tcttgcaaag ggactacttg tcaatattta tactgattct    960
 aaatatgcct tccatatcca gtaccaccat gctgttatat gggcagaaag aaatttcctc   1020
 actacataa                                                           1029



      <210> 2307
      <211> 383
      <212> DNA
      <213> Homo sapiens


      <400> 2307
 acgagaaagt gcggccaact tccgaggtca gtctcattgc ccagcggacc ccagcctctg     60
 ccaggttcgg tccgccatcc tcgtcccgtc ctccgccggc ccctgccccg cgcccaggga    120
 tcctccagct cctttcgccc gcgccctccg ttcgctccgg acaccatgga caagttttgg    180
 tggcacgcag cctggggact ctgcctcgtg ccgctgagcc tggcgcagat cggtgagtgc    240
 ccgccgcagc ctgggcagca agatgggtgc ggggtgctca gcgcggaccc ggcggcagcc    300
 cctccggctg agtcggccct gggggactgg agtcaagtga gctgtctgcg aagtgcattg    360
 ggctccggaa agcagggctg gga                                            383



      <210> 2308
      <211> 1308
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1308)
      <223> n = a,t,c or g


      <400> 2308
 tttctatttt tgagataggg tctcactctg ttttccaggc tagagagcaa tagtgcaatc     60
 acacctcact gcagcctcag tctcctgggc tcaggcgatc ctcccacctc agactcccga    120
 gtagctggga ccacaggagg gcaccaccat acctggtttt aaaacttttt gtagagatgg    180
 ggtctcacta tgttgcccag gctggtttca accttctggg ctcaagtgat cctctcacct    240
 caagcctccc ataagtgctg ggactacagg catgagccca cacctagccc caatttagtg    300
 aattttaagg aaggcatttt aaaaaaatga aaactaaaac ataggaggga tatccgaggg    360
 ttctaagggt taaggaattt tctttatgaa acctggcttg ggaacacagt tgtaaacaaa    420
 tgggactgat ttatgatgga aggcacgttt cttgctgcag atcatggtct gaagtttgaa    480
 agccaccagc cctagagggt tctgaaaact tctccttcct aacacagctg aaggaaaagg    540
 ggtgggtagg ggccggaggc acagggacat ctccagggtt tgggactttt ccaacatgat    600
 ttgcagaagg cacttgattc tgggaaagta ggacctttgg gcatttcgac cctcacccac    660
 actcccacac ccacttctgg cacagatcgg tgggtgcatc ccgagggcag gggctgagtt    720
 aggaacaggg acatccctag gacttcgggc gggcagtgga ctatttattt caggaaatgg    780
 gccacatcaa ggggcccgcc tgcccttcat cctgcaaggg gtacttgggc atgtggaggc    840
 ccctttctcc cctggtgttg caactggaga ggagtcggtt cctgaagaac agatgggaga    900
 gtgctggggc caggtaccct gggagagagg agggaaatgc aatccggcac aggggctgcg    960
 gggatcgggg cagtcaggag gcggcaagtg cggtgcaagg gcccccccac gcggccagct   1020
 gtggaacttc caccacgact ccctgtcctc tcctgagccc gcccatcacg tgtagaagct   1080
 cagatgctgg gcgccaggag ggcggcttcc tggctctggg caccgtggtt ctgtcctaac   1140
 gaggggcgct ctctgggtgt aaaaacagat gttctggctg ggcgcggtgc tcacgcctgt   1200
 aatcccagca ctttgggagg ntgaggtagg tagactgcct gagctcagga gttcgagact   1260
 gcagtgagct atgatctgag ccactgcatt gcacccgaca gggaggcc                1308



      <210> 2309
      <211> 427
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(427)
      <223> n = a,t,c or g


      <400> 2309
 aatacagggt gtcgagggtg agggtgcgct tcaccacgct gatgaagcgc tggatctcca     60
 gcagcactgc gttggtgtag ggccattgca cgtggtcgtc cgggcttggg acaggcctct    120
 gccctaccac agggtccagc tcctgcccct tggctggggc ggagggaggc tgtgcacttc    180
 cgggaccctc cagccatctc caaaccgcag cctcccattc tgggtctctc tggctcgcag    240
 acctgccacc tctgggtact taagcagaat gaggagccca tatggagcac agggtggtgc    300
 tcgtggtttc tgtgccacca aaaaaaaaaa aaaaaaaggg ggtttggttt taccaacctc    360
 ccccccggga aagggccttt gtggttttgg tttttttggg gccaaaaaaa aaggctcccc    420
 ccccccn                                                              427



      <210> 2310
      <211> 531
      <212> DNA
      <213> Homo sapiens


      <400> 2310
 tcaacgactg gctttacaag gctcatagga aaggtgcgtg tattcagacg gacacgattc     60
 cagctgtggc tcctccactt tcagggtcgc tgtttccaca gttgacaagc aggagaacca    120
 tacttgttgc acttccctca ctgggctgcc gccagcatca tatagaaaaa cgctgtccca    180
 acataagcca aagccaccat gactgggata gtcgccaaac agaactcagc ttcggttccc    240
 ctcccggcaa ggctggttcg acctacagtc aacaggaagc tcctgggggc agggacagga    300
 tccctgcctc ggaaggaggc aagacgtgaa cgttttttgg acggcgatca ggatggtgat    360
 gagggtccca gacaaccttc tatgggactg ccacataagc aagtccaaaa ccgagcaatg    420
 gcaaaagtgg taattacttt tgcaccaact aatgcaatgc aactagccag gtcgcctaaa    480
 acacttaatt tcatgaaaat aattggggag atggagtctg ttctagaata a             531



      <210> 2311
      <211> 1431
      <212> DNA
      <213> Homo sapiens


      <400> 2311
 atggtcaacc ccaccgtgtt ctttgacacg gagcccttgg gccgcatctc ctttgagctg     60
 tttgcagaca agtttccaaa gacagcagga aactttcatg ctctgagcac tggagagaaa    120
 ggatttggct ataagggttc ctgctttcac agaattgttc cagggtttat gtgtcagggt    180
 ggagacttca catgccatga tggcactggt ggcaagtcca tctacaggga gaaatttgat    240
 gacaagaact tcatccggaa gcatacagtt tctggcatct tgtccatggc aaatgctgga    300
 cccaacgcaa acagttccca gtttttcatc tgtgctgcca agactgagtg gttggatggc    360
 aagcatgtgg tcttcagcaa ggtgaaagaa ggcatgaata ttgtggagac catggagtgc    420
 tttgggtcca ggaatggcaa gaccaaggga gctgggctag caggcagcca ctctcaaaga    480
 tggctggctg catctgtgtg cggtgcctct cagccaagca gactcctctc aactgcgtgc    540
 cggcagcaaa aactccagat ttctggtcgc tccaaaggct gttctagaaa aacctctggt    600
 ctggaggacc aaggcctaac taaagatggt acaaacaaca cacagggcat caagcttcag    660
 cttggtgaag aggaggagca tagcccacgt cccagctccc ttgtccccgt gtcacagctc    720
 aaggctaacg gcagctctag tgccagcatt gcttgtgctg aggatgggcc agcacgtcct    780
 gtgcccgggt gccagtgtca gaatcaaggg caccatcaaa ataagaggcc aaggacttct    840
 cagctatgcc aaatgccaaa gacgcatctt gttgtggcgg atgcccggcc caacatcagc    900
 cgggtttttt ttggccttcc ggagcgggaa tccgcgcttt ggagctttcc cagagactgg    960
 ctggtgaatc tgcttaatca gtgcgatgag ctgggcattc gtaaccagtt tgaagtggaa   1020
 gtcctgagct acggtcatct gccgctggcc tactccgccc gctgctttac cgcgcgttcg   1080
 gaagaccgcc cgaaagatga gtgtgaaacc tgctgcatta agtatccgaa cgggcgcaac   1140
 gtgctgtcgc aggaaaacca acaagtgttt gtactcaatg gcattcagac catgagcggc   1200
 tacgtttaca acctcggtaa cgagctggca tccatgcagg gcctggttga tgtggtccgc   1260
 ctgtcaccgc agggtactga cactttcgcg atgctcgacg ccttccgcgc taatgaaaat   1320
 ggcgctgcac cactgccgtt gacggcgaac agcgactgta acggctactg gcggcggctg   1380
 gcagactttg agtgcacctg ggcccactcc caagggggct gtcatgcata g            1431



      <210> 2312
      <211> 2727
      <212> DNA
      <213> Homo sapiens


      <400> 2312
 ggaaataata tggaagaatg aatacttcat tttaattgat cttccagggt gactgtgaag     60
 atcacgctaa ccttctgtgc agccttcttc ttggatatgg attagaagcc tttgtttgtg    120
 ttgggaccaa ggcaaaagga gtacctcatg catgggttat gacttgtgga actgatgggg    180
 ccatcacttt ttgggagagt ttaacaggac acaggtacat ccataaacct accaatcctg    240
 atgaacctcc agttgctgaa cagcccaaac cactgtaccc atatcgaaca attggttgtg    300
 ttttcaacca tcagatgttc ctgggaaatt gtcaaccctc tgatgcagta gaaacctgtg    360
 tatttgattt gaacgatgaa tccaaatgga aacccatgag tgaggaagca attaaatctg    420
 tgtgtgctcc tggagctaca acatcccttc ctccctttcc acctctgtgt gcatccacaa    480
 ttgacgcgtc agtaacaagt aatgaaattg aaatgcagct gaggctcctg gtgtcagaac    540
 acaggaagta taccaaaatc cacacatgtc caagccccac tggtggccct gtagaacctg    600
 cagatacaaa gagtcagccc tctgtatgca tggatttcac atcccatgaa taccgtattt    660
 ccgacccgtt tttggttgaa aaaaatttgc ctaaagaaaa aactgccaac acagccggac    720
 atcagaagga acaaactggg gacacgctgc ctttaagaaa cataacaggc accgtgaggg    780
 tccacggctt cattcttgaa gttagtgaga ccaagaaccc acctaatccc gggcacaaaa    840
 ccacctcaat ctcccaaaga ccgaaagccc tggtgtcgct gggaccagag gtgagacgtg    900
 gaacacgtgg ggaagatgag aaggcgctgg agaaggaggg tggtggtcgc agatgggaat    960
 gtggtggagc caatgagctg tgcgggagac ctccagcctt caccagggta actgtgcatt   1020
 ggggaaaggg aaatgatcag acatttcagg acctattgga cactggctct gagctgacat   1080
 tgattccagg ggacccaaaa cgtcattgtg gtcctccagt taaaataggg gcttatggag   1140
 gtcagataat taatggagtt ttagctcagg tccaacttac agtggatgca gtgggtccct   1200
 ggactcatcc tgtggttttt cccagtgcca gaatgcataa ttggaataga catactcagc   1260
 agctggcaga atcccacatt ggctccctga ctgtccattt atctagtgac ccaaaaggct   1320
 gccattctga gtggggtcca gaacaggaga aggctctgca agaggtccag gctgctgtgc   1380
 aagctgctct gatacttgag ccatatgacc cagcaggtcc agtggtgctt gaggtgtcac   1440
 tggcagatag ggatgctgtt tggagccttt ggcaggcccc cataggtgaa tcacagcaaa   1500
 ggcctctagg attttggagc aaggccctgc catcttctgc agccataaag cgtgtcatgc   1560
 acagcagcat tccatcatca aatggaagtg gtatatacat gatcgggctc gagcaggtcc   1620
 ggaaggcaca aatagttctg cacgatatgc agccaccatg tgaaaatggg acagcttcag   1680
 cactacagcc tctttctagg aaatccttga aggacagcag tgaagggaaa tcttcccagt   1740
 gggcagaact tcgagccgtg cacctggctg tgcacgttgc atggaaggag aaatggccag   1800
 atgtgcgatt agatactgat tcatgggccg tagccaatgg tttggccaga tggtcaggga   1860
 cttggaagga gcatgatagg aaaattggtg acaaagaagt ctggggaaga ggtacgcgga   1920
 tagaactctc tgagtggtca aaaactgtga cgatatttgt atcccattgc ttctaccaag   1980
 actaccatcc atccgtgggc tcacagaatg ccttatacac caacatggta ttccacacag   2040
 cattgcctct gaccaaggca ctcactttac ggctaaagaa ttgcaacagt gggctcatgc   2100
 tcacggaatt cactggtctt accatgttcc ccatcatcca gggttggggc aaagttctcc   2160
 agaaggccgt gtatgctctg aatcagcgtc caatatatga atggaaggaa gaatcatgct   2220
 tgcacacagg tgtggctgat gcgctcagag gcaactgggc agaaggccac agggagcaca   2280
 aggccttgtg gctgggcctc tggagcacct ggtctcagca cccgctcagg tccttgaaga   2340
 cgaccagaca ccatccaggg cttggtgtac tctctgaaga tatatgcgag gcagggggag   2400
 ctacagaaga gctgtccagg gcctctggtt ttgccacagg gtatgggaag agaaaagaag   2460
 acactaagaa gcataagcag cactctgtgt cagatataat gtaaggaaca caatctgcca   2520
 aagaactggc ctaagccatt tcctaagaat tttccttcac agaacgtgta atatcaaaaa   2580
 taacttgcct tttatcttaa atactcaaag cttcaaaacc ttataatgtc cataattcat   2640
 tacatcgtca gaaaaaaact gaaataccat ttcatttcca aaagaagtca agatatactt   2700
 ttacctatga tttaaagcag aacaagc                                       2727



      <210> 2313
      <211> 687
      <212> DNA
      <213> Homo sapiens


      <400> 2313
 gaactagaat agctgaaaca attttgaaaa agaaaactaa agtgggagga accattttat     60
 ctgattttaa gatgaataaa gctagagttc tagagatagt gtggtatttg tggagtaaca    120
 gatgcatgaa tcaatggaac agaatagagg acccagaaac agatccacaa acaaatggtg    180
 ctctagcgat tggacatcca cagaccaaac aaataaaatt aacaaatcga ccccaaagcc    240
 tcaacctaaa cctcagacct gatatgaaaa tgaattcaaa atggatcgta gacttaaatg    300
 taaaatgtga agctattaaa acttttagaa gaaaacaaga gaaaatcttc accaccaaaa    360
 acataatcta gaagataata tatataagtt gaactttaaa atttgctctg caaaaagtgc    420
 tgttagagaa ttaagaaaaa actacagcct gagaaaaaat atttgcaaac cgtctatcca    480
 acataggact catatctaga gaatataaac aactcttaaa gcttagcagc taaaaaacag    540
 tttaattaga aaatggtggc ctggcatggt ggctcacacc tgtaatccca tcacttcggg    600
 aggctaaggt ggatgaacca cttgaggcca ggggttcaag accagcctac ccaacatggt    660
 gaaaccctat ctctactaaa aaaaaaa                                        687



      <210> 2314
      <211> 948
      <212> DNA
      <213> Homo sapiens


      <400> 2314
 gaaatgttca gcctatttaa tttccacgtt tgcctaatgc atgtgctcta tctctggatt     60
 tacagttatc gtccattatg agctgggaat ttctagagga cctctgtgtg tgtgttagtg    120
 tagcacttag cacaatgtca taaataaata ggcttttaat catgctgatg atattgatca    180
 cactcacgat gtctgggaga gaaggtgttg gctgtgctgc tcagtggtct tgatttctta    240
 gaactggagc atgaacaaca tgctcgaaat gcgaagtaat gaactggaac ggtggagaag    300
 gtcataaaaa gcctacctgg aggaggatag tgacggcact gtcacaaatg ctttatatgt    360
 attatttaat tcttgcagtt ccctcctgcg gtaggtccaa ttattatcct catgttcgag    420
 tgaaggaaac tcaagcaggg tgaggttagg ttaataactt gctaaagtca catggcaagt    480
 aagtgtggag ccgggatttg aacccagtca tcctggctcg gggtccaatg ccctggctgg    540
 ccctggatgc cgctgggggg ccctctgtag ggctgacttg ccctcctgag aagccccttc    600
 cttagcttac ggccacatag ccctctggta gtcctcatca ccagctctgc tcttaatttg    660
 gccattttcc gccttaggat tggagtgaat catccttcaa agacagagcc acgttctgca    720
 ctgtgttaag catagtccgt ggctcacagt tcatgcgtga gccacacaca catgcacact    780
 ttgttgggaa gaagagcaac aataaattgc ttatttagaa atgggcgagg ccaggtgcag    840
 tggctcacat ctgcagtccc agcactaagg aaggcagatg tgggaggata gcttgagccc    900
 aggagttcaa gacctgcctg ggcaacatag caagtcccag ttctccac                 948



      <210> 2315
      <211> 575
      <212> DNA
      <213> Homo sapiens


      <400> 2315
 taaaagtttc ctgcagtgag gaaatagcca gaaagaacac tccacccctc ctccttttta     60
 taactatagg gtctggctcg acagagcagg agcatcgcca tcttggacaa gcccctcatt    120
 ctaaagttca ccttaataaa aaactgccta aattcaaact gcatcagcct aatggctaag    180
 gtcagcatga ccataaacca caaataacat ctccaaccgg aaacattcga aactcctcct    240
 cgaccagaga catgctagtc ccgagataac ccccctccag cagggaagat gccagtctcg    300
 ggataacctc tctctggccg gaaagatgcc tgccccaaga taaacttgcc tcctcccaga    360
 gatattccaa ccctgccata aaacttctcc ctcaaacagg aacattccaa aattctgata    420
 atctccctca ccctaaaacc aatatatact cctagtctgt aagagaaagc gctcttgacc    480
 aaaattcacc aggagtgcct cccaggtttt aactaaagaa aacctctctt taactgccaa    540
 aaaaaaaagg aaaaaaaaaa agctttctgc agtgg                               575



      <210> 2316
      <211> 678
      <212> DNA
      <213> Homo sapiens


      <400> 2316
 tttttttttt ttgtacatca aaatgagtta ttttaatgaa tgaaaaacat taaatctacc     60
 agtctacaga aaaagaaaat gtgtatttga catcgtttaa ggtggctctt acatcaactc    120
 cttacttgga aaactggtat ttaaatgtca agaattaagc ttttctcctg tcttcccagc    180
 attgacgatt tcgaaaaatt tttgatacta ttctacgtaa cactgcttta gctaaggtaa    240
 gtatatcttc ttagttccaa gtatcctatc cagcctgctc tccagtcatt cctgcttaag    300
 gaactccctg tggctgggct gaaacaggac tctttccctt gctccagatg agaagaccaa    360
 agctggtttg gaagtggggt ggcactacaa agggccacag cctccatagt tctccagcat    420
 cacatccctg tacaaggccc tctcggcagg cacccatgat ggcccattcc ttcgtagtga    480
 agtacacagc cacgtcctca aaagccactg attcctgggg cctggttgtt aaggacacag    540
 ctgtcatcat ctgacctctt ttcttccttt ctgggtaaag gtaaaagtct caggtgctga    600
 ggatatgccc cttggggcct ctccatccag agctccccga ggaaccgagc accagggtgt    660
 ttcccctcgc tccagctg                                                  678



      <210> 2317
      <211> 4805
      <212> DNA
      <213> Homo sapiens


      <400> 2317
 gaaaaaggct tgaaaacata caaaaaaccc tagaggtggc tttctcagag gcagtgtgga     60
 tgcagccatc tgttgtcctg ctggatgacc ttgacctcat tgctggactg cctgctgtcc    120
 cggaacatga gcacagtcct gatgcggtgc agagccagcg gcttgctcat gctttgaatg    180
 atatgataaa agagtttatc tccatgggaa gtttggttgc actgattgcc acaagtcagt    240
 ctcagcaatc tctacatcct ttacttgttt ctgctcaagg agttcacata tttcagtgcg    300
 tccaacacat tcagcctcct aatcaggaac aaagatgtga aattctgtgt aatgtaataa    360
 aaaataaatt ggactgtgat ataaacaagt tcaccgatct tgacctgcag catgtagcta    420
 aagaaactgg cgggtttgtg gctagagatt ttacagtact tgtggatcga gccatacatt    480
 ctcgactctc tcgtcagagt atatccacca gagaaaaatt agttttaaca acattggact    540
 tccaaaaggc tctccgcgga tttcttcctg cgtctttgcg aagtgtcaac ctgcataaac    600
 ctagagacct gggttgggac aagattggtg ggttacatga agttaggcag atactcatgg    660
 atactatcca gttacctgcc aagtatccag aattatttgc aaacttgccc atacgacaaa    720
 gaacaggaat actgttgtat ggtccgcctg gaacaggaaa aaccttacta gctggggtaa    780
 ttgcacgaga gagtagaatg aattttataa gtgtcaaggg gccagagtta ctcagcaaat    840
 acattggagc aagtgaacaa gctgttcggg atatttttat tagagcacag gctgcaaagc    900
 cctgcattct tttctttgat gaatttgaat ccattgctcc tcggcggggt catgataata    960
 caggagttac agaccgagta gttaaccagt tgctgactca gttggatgga gtagaaggct   1020
 tacagggtgt ttatgtattg gctgctacta gtcgccctga cttgattgac cctgccctgc   1080
 ttaggcctgg tcgactagat aaatgtgtat actgtcctcc tcctgatcag gatggaagtt   1140
 ccagctctga tagtgaccta agtctgtctt caatggtctt tcttaaccat agcagtggct   1200
 ctgacgattc agctggagat ggagaatgtg gcttagatca gtcccttgtt tctttagaga   1260
 tgtccgagat ccttccagat gaatcaaaat tcaatatgta ccggctctac tttggaagct   1320
 cttatgaatc agaacttgga aatggaacct cttctgattt ggaggacgaa tccatgaacc   1380
 aaccaggacc aatcaaaacc agactggcta ttagtcagtc acatttaatg actgcacttg   1440
 gtcacacaag accatccatt agtgaagatg actggaagaa ttttgctgag ctatatgaaa   1500
 gctttcaaaa tccaaagagg agaaaaaatc aaagtggaac aatgtttcga cctggacaga   1560
 aattctttga tgaaatcact gagctgacat acctgccctc ttttcaccat aaagctgctc   1620
 ctcaccaggc cgagccaggt cccaattctt cctcagcctc tgctccccca ccctataatc   1680
 cttttatcac ctcctctcct cacactcagt ccggcttaca gtttcgttct gtgactagcc   1740
 ctcccccatc tgcccaacaa tttcctctta aagaggtggc tggagctaaa ggcatagtca   1800
 agacagcttt agagactgct cccacactag ctctccctgt ctcatcccaa cccttttcat   1860
 tacacacagc cgaagtgcag ggctgtgcag tcggaattct tacacaagga ccgggaccat   1920
 gccctgtagc ctttttgtcc aaacaacttg accttactgt tttaggctcg ccatcatgtc   1980
 tccatgcggt agcttccgct gccctaatac ttttagaggc cctcaaaatc acaaactatg   2040
 ctcaactcac tctctacagc tctcacaact tccaaaatct attttctttc tcacacctga   2100
 cgcatatact ttctgctccc cggctccttc agctgtattc actctttgtt gagtctccca   2160
 caattaccat tcttcctggc ccagacttca atctggcctc ccacattatt ctggatacca   2220
 cacctgaccc tgatgattgt atgtctctga tctacctgac attcacccca tttccccata   2280
 tttccttctt ttctgttcct catgttgatc acatttggtt tactgacggc agttccacca   2340
 ggcctgatcg ccactcacca gcaaaggcag gctatgctat agaatcttcc acatccatca   2400
 ttgaggctac tgctctgccc ccctccacta cctctcagca agccgaactg attgccttaa   2460
 ctcgggcctt cactcttgca aagggactac acgtcaatat ttatactgac tctaaatatg   2520
 ccttccatat cttgcaccac catgctgtta tatgggctga aagaggtttc ctcactacgc   2580
 aagggtcctc catcattaat gcctctttaa taaaaactct tctcaaggct gctttacttc   2640
 caaaggaagc tggagtcaca cactgcaagg gccaccaaaa ggcgtcagat cccattactc   2700
 taggaaatgc ttatgctgat aaggacagga cgatagatgg ttcctcccag gtgattgagg   2760
 aaaaaaacca caatgggtat tcagtaattg atacggggac tcttgtggaa gcagagttag   2820
 aaaaattgcc taataactgg tctcctcaaa cgtgtgagct gtttgcactc agccaagcct   2880
 taaagtactt acagaatcaa aagactatct caatcctgat tcaaaaggaa cccagcccag   2940
 ctctaggact cacccctgag cgcaaaggca atgttgggca tgctggtaaa ggaccactag   3000
 aatccagcag cccagacccc tttctttgtg gtcaagaaag gcgggaaaag gggtgcagga   3060
 ctgctacatc ggtaagcata actaatccga taaacagagg tccatgggtg gttacgcacc   3120
 ctggaaagga actcacccct gagcacaaag gcaatgttgg gcacgctggg agagacattc   3180
 tagcaaaagc aggggccatt atacacctga acataggaga aggaacaccc gtttgttgtc   3240
 ccctgcttga ggaaggaatt aatcctgaag tctgggcaac agaaggacaa tatggacgag   3300
 caaagaatgc ccgtcctgtt caagttaaac taaaggattc cacctccttt ccctaccaaa   3360
 ggcagtaccc cctcagaccc aaggcccaac aaggactcca aaagattgtt aaggacctaa   3420
 aagcccaagg cctagtaaaa ccatgcagta acccctgcag tactccaatt ttaggagtac   3480
 agaaacccaa cagacagtgg agaaaccttg tgccatcaag ccacccaagc gctcttcaat   3540
 ttcctcgcta cctgtggcta catggtttcc aaaccaaagg ctcaactctg ctcacagcag   3600
 gttacttagg gctaaaatta tccaaaggca ccagggccct cagtgaggaa cacatccagc   3660
 ctatactggc ttatcctcat cccaaaaccc taaagcaact aaggggattc cttggcgtaa   3720
 taggtttctg ccgaaaatgg attcccaggt atggcgaaat agccaggtca ttaaatacac   3780
 taattaagga aactcagaaa gccaataccc atttagtaag atggacaact gaagtagaag   3840
 tggctttcca ggccctaacc caagccccag tgttaagttt gccaacaggg caagactttt   3900
 cttcatatgt cacagaaaaa acaggaatag ctctaggagt ccttacacag atccgaggga   3960
 tgagcttgca acctgtggca tacctgacta aggaaattga tgtagtggca aaggtggtgg   4020
 cagtagcagt cttagtatct gaagcagtta aaataataca gggaagagat cttactgtgt   4080
 ggacatctca tgatgtgaat ggcatactca ctgctaaagg agacttgtgg ctgtcagaca   4140
 actgtttact taaatgtcag gctctattac ttgaagggcc agtgctgcga ctgtgcactt   4200
 gtgcaactct taacccagcc acatttcttc cagacaatga agaaaagata aaacataact   4260
 gtcaacaagt aatttctcaa acctatgcca ctcgagggga ccttttagag gttcctttga   4320
 ctgatcccga cctcaacttg tatactgatg gaagttcctt tgtagaaaaa ggacttcgaa   4380
 aagtggggta tgcagtggtc agtgataatg gaatacttga aagtaatccc ctcactccag   4440
 gaactagtgc tcagctagca gaactaatag ccctcacttg ggcactagaa ttaggagaag   4500
 aaaaaagggc aaatatatat acagactcta aatatgctta cctagtcctc catgcccatg   4560
 cagcaatatg gaaagaaagg gaattcctaa cttctgagag aacacctatc aaacatcagg   4620
 aagccattag gaaattatta ttggctgtac agaaacctaa agaggtggca gtcttacact   4680
 gccggggtca tcagaaagga aaggaaaggg aaatagaaga gaactgccaa gcagatattg   4740
 aagccaaaag agctgcaagg caggaccctc cattagaaat gcttataaaa caacccctag   4800
 tatag                                                               4805



      <210> 2318
      <211> 2922
      <212> DNA
      <213> Homo sapiens


      <400> 2318
 atgctgttag caactgctct gaggggcttt ctaaagaatg gggaccgagg ccatgtagac     60
 acagaggaat ggagaagcta cccttgggcg gcaagttttg gccaactcag gagcagtcag    120
 aactgtccgg gcgcgtctgc aagcggacgg acgggcgttc caaccgtgct ggtggcccgt    180
 accgatgctg atgcgtcgga tctgatcacc tccgattgcg acccgtatga cagcgaattt    240
 atgaccggcg agcgtaccag tgaaggcttc ttccgtactc atgcgggcat tgagcaagcg    300
 atcagccgtg gcctggcgta tgcgccatat gctgacctgg tctggtgtga aacctccacg    360
 ccggatctgg aactggcgcg tcgctttgca caagctatcc acgcgaaata tccgggcaaa    420
 ctgctggctt ataactgctc gccgtcgttc aactggcaga aaaacctcga cgacaaaact    480
 attgccagct tccagcagca gctgtcggat atgggctaca agttccagtt catcaccctg    540
 gcaggtatcc acagcatgtg gttcaacatg tttgacctgg caaacgccta tgcccagggc    600
 gagggtatga agcactacgt tgagaaagtg cagcagccgg aatttgccgc cgcgaaagat    660
 ggctatacct tcgtatctca ccagcaggaa gtgggtacag gttacttcga taaagtgacg    720
 actattattc agggcggcac gccggataag gcgttcacgc cgcatccggc aagcaaacca    780
 gctcataagc cgggagaaca acctatgaaa aacaatccgc tgatctcaat ctatatgccg    840
 acctggaacc gccaacaact ggcgattcgg gcaataaaat cggttttgcg ccaggactac    900
 agcaactggg agatgatcat cgtggatgat tgctccacct cctgggaaca actgcaacag    960
 tacgtcaccg ccctcaacga tccgcgtatc acttacattc acaacgacat taacagcggg   1020
 gcgtgcgcgg tacgtaacca ggcgattatg ctggcgcaag gggaatatat caccgggatt   1080
 gatgacgatg acgaatggac acccaaccgt ctgagcgtct tcctcgccca taaacagcaa   1140
 ctggtcacac acgccttttt gtacgctaac gactacgttt gccagggcga agtctattcc   1200
 caaccggcaa gcttgccgct gtatcccaaa tcgccgtatt cacgccgcct gttctacaaa   1260
 cgcaatatca ttggcaacca ggtctttacc tgggcatggc gtttcaaaga gtgtttgttc   1320
 gataccgaac tgaaagcggc acaggattac gacatcttcc tgcggatggt ggtggagtac   1380
 ggcgaaccgt ggaaagtaga agaggcgacg cagatcctgg ctatcaatca cggtgaaatg   1440
 ccgattcact cgtcacgaga acatttccgg gtacttccct tttgccgaag cacaagacca   1500
 tttcgacagg ccaggaaaat atcgagggta atcgtcacct ccacaaagag cgactcgctg   1560
 tataccgttg gcatgctagc tttatctgtt cgggcaatac gatgcccatt gtacttgttg   1620
 actggtctga tatccgtgag caaaaacggc ttatggtatt gcgagcttca ggtcgcacta   1680
 cacggtcgtt ctgttactct ttatgagaaa gcgttcccgc tttcagagca atgttcaaag   1740
 aaagctcatg accaatttct agccgacctt gcgagcattc taccgagtaa caccacaccg   1800
 ctcattgtca gtgatgctgg ctttaaagtg ccatggtata aatccgttga gaagctgggt   1860
 tggtactggt taagtcgacg aatgcagatt gaagaaacct tccgagactt gaaaagtcct   1920
 gcctacggac taggcctacg ccatagccga acgagcagct cagagcgttt tgatatcatg   1980
 ctgctaatcg ccctgatgct tcaactaaca tgttggcttg cgggcgttca tgctcagaaa   2040
 caagggctgg atctcggtgt ctatggcgcg ccagaaacgt ttcttattga cggcaacggc   2100
 atcattcgct atcgccatgc gggcgatctg aatcctcgcg tctgggaaga agagatcaag   2160
 ccgctgtggg agaaatacac gctggcgacc atcgatgtgt tgcagtttaa agatgaagca   2220
 caggaacaac agttccgtca gctcactgaa gaactgcgct gcccgaaatg ccagaacaac   2280
 agcattgccg attccaactc gatgattgcc accgacctgc gtcagaaagt gtatgaactg   2340
 atgcaggaag gtaaaagtaa aaaagagatt gtcgattata tggtggcgcg ttacggcaac   2400
 ttcgtcactt acgatccgcc gttaacgccg ctgaccgtgc tgctgtgggt gctgccagta   2460
 gtggctattg gcattggcgg ttgggtcata tacgcccgct cgcggcgtcg ggtacgcgtg   2520
 gtgccggaag cgtttcctga acaaagcgtg ccggaaggta agcgtgccgg atatgttgtt   2580
 tatctgccgg gtattgtggt ggcgttaatt gtggctggcg tcagctacta ccagactggc   2640
 aattatcagc aggtgaaaat ctggcagcag gccacggcac aggctccggc gttgctggac   2700
 agggcgctgg atccgaaagc cgatccgctc aacgaagaag agatgtcgcg tcttgcgctg   2760
 gggatgcgta ctcaactgca aaaaaatccg ggagatatag aaggctggat tatgttgggc   2820
 cgcgttggca tggcgctggg taacgccagt atcgccaccg attgctacgc cactgggtat   2880
 cggctcgatc ggacaacagt gatgctggat ggggataggt ga                      2922



      <210> 2319
      <211> 1773
      <212> DNA
      <213> Homo sapiens


      <400> 2319
 atggccttgg gaatctctgc ccctgtggct ttgcagggta cagccccact cctggctgtg     60
 cttagtggct gcagctttcc caagcacatg ttgcaaactg tcaatggatc accattctgg    120
 ggtttggaga atggtggccc tcttctcaga gctcgactag gcagtgctcc agtggagact    180
 ctagaactgt tttcatcgct caataaaatt ctccactctt accattcttc agttgtcaag    240
 tgtgacctca ttcttcttgg acgctggaca aaagcttggg acccactaag tgcaggtgga    300
 ggctgtcaca ctggcccttt gcccttgcaa gtggagggca accaccccac tggcagctac    360
 agggttccta acaggccaca gtaccggtct gtggcctggg gcttggggac ctctggtctg    420
 gtcaattaca catttctcct gaattctgga gagacaacat accagttcct cagaggaaac    480
 aaagattttc ttaaaaatca catcaaatta aattactgct ttttgcttat tgaagtggat    540
 aatcttactc ttgtttttgt cattgaaaag acactaggcc agatatttga tattccaaag    600
 gtagagcttc tcttctccta ccaatgcttt ccaatggttg aaaacagaca gaagccagag    660
 ggtgaggaag actgtgtgat acagttgtca gagctcagct gcacagaatg cagcaaaaaa    720
 gcatggagaa tggaggttct gcataccaac aaaaccacca atgccaccca gtgtggaggg    780
 cccgctcagc ttcaacaatt caacgctgtt ctttctgaaa aagtacacat cgtgccttct    840
 ctacttcgct cttggaacat aatttctcat ggcagatttc catcatttga aacttttaat    900
 acaaagaact gcatagcgta taatccaaat ggaaatgctt tagatgaatc ctgtgaagat    960
 aaaaatcgtt atatctggtt ggagaagcct caggaaactt acagtaatga cagaagggaa   1020
 agcaaacaca tccctctacg catggcagca gaaaggagac gtgctgagca aaaggaaaaa   1080
 taccctctta ttaaatcatc agatctaggg gcttccgagg cgatccggca gcgtcagtct   1140
 tcagctgcta agctgagaaa atctgggaag gagtcagtca gagagccttg ggccagagtt   1200
 ccaggggctc tgggagtggc tgccagggca ctgatagcag aagatgctgg cttgagtaga   1260
 gtgatcttat ttcattatgg tgaaagttgg aacctcttac gtgccgatca acgtctcatt   1320
 ttcgccaaaa gttggcccag ggcttcccgg tatcaacagg gacaccagga tttatttatt   1380
 ctgcgaagtg atcttccgtc acaggtattt attcgcgata agctcatgga gcggcgtaac   1440
 cgtcgcacag gaaggacaga gaaagcgcgg atctgggaag tgacggacag aacggtcagg   1500
 acctggattg gggaggcggt tgccgccgct gctgctgacg gtgtgacgtt ctctgttccg   1560
 gtcacaccac atacgttccg ccattcctat gcgatgcaca tgctgtatgc cggtataccg   1620
 ctgaaagttc tgcaaagcct gatgggacat aagtccatca gttcaacgga agtctacacg   1680
 aaggtttttg cgctggatgt ggctgcccgg caccgggtgc agtttgcgat gccggagtct   1740
 gatgcggttg cgatgctgaa acaattatcc tga                                1773



      <210> 2320
      <211> 367
      <212> DNA
      <213> Homo sapiens


      <400> 2320
 agcgcaatta aacctatttg tgcacagaag agctgactgt gctcagttcc tcggaggtct     60
 tgaaggaggc gtgttaaggc cctcccttca gagcccatct tgctggcatc accgtgtacc    120
 atgccacgct agggtcttga cacagtgatg cggccctgct gctggtgggc cacgctgtgt    180
 ggcaaacacc ttagaatgtg ttctcacgcc ctaaagatgc gtccaaacgc ttcagcagca    240
 gaaactgaac agttgaatgc acacagccgc gggctgatga attcatcatc caggcctgct    300
 ccctgagagc tccggagggc gggaatgggt cgtggagcct gggttgtcaa tccccacacc    360
 tgagagc                                                              367



      <210> 2321
      <211> 3243
      <212> DNA
      <213> Homo sapiens


      <400> 2321
 ttagtcgact ctaaggatcc cccggacttt ccagcagtcg agcattaacc agaaatcctc     60
 accgcatttt tcacgcatat ccgcgaccat agcggcatct ttgcggatcc ccgcatcgcc    120
 atcatgtggc ccccagtgcg tcggcatttt gccaccgata aagcccatca tcttttgcca    180
 gatccggacg cgcacagagc cagatcgaca caagaaatcg tattcatcac caggccacca    240
 gagccggagt aatacagggt ggcactgagc atttgatcgt ggatcagttc tgatatcact    300
 gacacattta ccctcaatga aacggttaag atgtttttcg acaataaaac agcccatttc    360
 accggctgtc gaaacggcga atccggtctg gccgttttct gcttcgactt caacaaccaa    420
 cgtgccaaga acgttaatgc caaatgactg gcgtgactgc tcgtaatcgc ggtatttact    480
 catcggggtg gcaatatgat cgtctatcca gtgattcgcc ccctggtcgt gataatcacc    540
 gccgccagcg cctttttctg ctgtcgcacc gccagtaaac caggcgcgaa cctgtttaat    600
 ttttggtagg gtcatgatgt tctccattgt tatgagggtg aaatatgcgc tggcgcaggc    660
 aatggccttg cccgccagat aatcacggta ttcttcattg atttgtaagc gggtaccgac    720
 caccgagatc gcagcggtaa gctcgttatt ggcgttaaac accggcgcag cgacacaacg    780
 gacatcggcg taatcttcgc cgttgtcata gctccagccc tgacggcgaa tacgcgccag    840
 ttcttcgtga agttgcagcc cttcgataat actttgctgt accgctgcag gttgccaggc    900
 aagcaggcat ttacctattc cggagcgata aagcgaaagg ctttttcctt catgggacga    960
 cacgctgata gtggctgatg actccactat ataaatggaa tggtaccgag ctgattgacc   1020
 tacgcgcaga gttggcttcg ctaccggcag cggcagacgc tgctcaataa taccgccacc   1080
 gaggcacact tcaccgttat agaagacggc agactggccc ggtgtcacgg cggcaaccgg   1140
 ttcatcgaaa atcacttcaa tgcgatcatc gtccagcgcc ttgacggtgc aagggatatc   1200
 ggtctggcga tagcgggttt ttaccgtgca acgcatagtg ccggtgaatg gttcgcgatc   1260
 gacccagtgc aactgctggg caatcaaccc gacagacatc agccgcgggt gttcatggcc   1320
 ctgagcgaca accaggaatg tttgttttcg acgtctttgt ccaccacata ccacggttct   1380
 tcggtacctt ctttggttgc caccgatacc cagaccttta cgcaatttca tcgccatcga   1440
 cggtaatgat aatgcccggt tgcgtccggg agataacggt cccaggaact cgcggaattt   1500
 acgttcgcca atgaagcaaa tgccggtaga gtcttttttc ttcgcggtga ccagaccaag   1560
 atcttcagca atcttacgca cctgcggttt ttccagttcg ccgaccggga acaggctttg   1620
 cgcaatctgc tcatggctga gcgtataaag gaagtagctc tggtctttat tgctgtccag   1680
 accacgcagc aggcggctct tgccatcgac atcggcccga cgtacgtaat gaccggtagc   1740
 gatataatcg gcacctaaat cttcggcggc aaattcgagg aaggctttaa atttgatctc   1800
 tttgttgcac agaatatccg gattcggcgt gcgaccggct ttatattcgg caggaacagt   1860
 tcgaagacgt tgtcccagta ctcggcagca aagtaacggt gtgcagttca tgccgagagc   1920
 cgggtccagg atcgtcttta aatccggctt atcggcgtaa tgatccatgg caaacagctt   1980
 accggtacgc gcaaagccgc tttgcacttc atcagcaatc atcacaatac cgtgctcgtc   2040
 gcacaggcgg cgaatagcgg caaccagctc ttttggcgca acgttgaaac cgccctcgcc   2100
 ctgcaccggt tcgaaaataa tcgccgccac ctgcttcgct tcgatgtctg atttaaacaa   2160
 gcgttcgatg gcgtcgaggg agtcctgtgt tgaaatgccg tgtaaatctg acggataagg   2220
 tacgtgatac accgaaccag ggaacgggcc gaagccgatt ttgtacggcg caacttttcc   2280
 ggtcagcgcc atggtcatat acgtacgacc gtgaaagccg ccgctaaacg caatcacgcc   2340
 agggcgtccg gtatgggcgc gagcaatttt caccgcgttt tccaccgctt ccgcaccggt   2400
 ggtgaagaac gcggttttgg cctgcccgct caccggggca agggcgttga ttttctccgc   2460
 cagggtgacg tagctttcat acggcacaat ctgatacgcg gtgtgggtaa actgttgcag   2520
 ttgctgctcc accgccgcga ccagatcagg gtggcgatgt ccggtattca gcaccgcaat   2580
 gcctgcggcg aaatcgatgt actcgttgcc ctcaacatcc ttcagcgtgg cgttttcagc   2640
 cgagccgcgc ccatcgcggt aaacggcaca cgcagcgtgc gcccgccggg gaacgggtaa   2700
 tgcggcagat tggcgaaggc atcgaaacgt tcggcgtcgc cgcgcagcag ttcggcaatc   2760
 aaacgtccgg ctagatgagt acaggtcacg ccgtggccgc tgtagcctca ggaggtcgtt   2820
 ttcaaacccc acggctcgga gagaacacag gcccttggtg accacagtgt tgagggaacc   2880
 gggcaggggc tctgccagga gccacgctgt tgatcctggc agggtttctg ccgagcgcac   2940
 accagaaccg tcccagccgc aatccggtat ccagaccgcc aaacacccaa cgggttgcga   3000
 ggcgcaaaca ctatgcactc gcagatggat acactgaacg gagatggacg aacgcacctt   3060
 aagcaactcc accacggttt ctgcaaatcc aaccacatac atagcaactg caacagcgtt   3120
 ggcaaaggcg aagattagac caattgcacc accaaattct ggccctagac ttctagatat   3180
 taaataatat gctcctcctg cttccaacag cagtttcctc aaaaacaagg gcaacatcgc   3240
 cat                                                                 3243



      <210> 2322
      <211> 663
      <212> DNA
      <213> Homo sapiens


      <400> 2322
 atgcctaatt tctttatcga tcgcccgatt tttgcgtggg tgatcgccat tatcatcatg     60
 ttggcagggg ggctggcgat cctcaaactg ccggtggcgc aatatcctac gattgcaccg    120
 ccggcagtaa cgatctccgc ctcctacccc ggcgctgatg cgaaaacagt gcaggacacg    180
 gtgacacagg ttatcgaaca gaatatgaac ggtatcgata acctgatgta catgtcctct    240
 aacagtgact ccacgggtac cgtgcagatc accctgacct ttgagtctgg ttcaggtgca    300
 gaacaaactg cagctggcga tgccgtgctg ccgcaagaag ttcagcagca aggggtgagc    360
 gttgagaaat catccagcag cttcctgatg gttgtcggcg ttatcaacac cgatggcacc    420
 atgacgcagg aggatatctc cgactacgtg gcggcgaata tgaaagatgc catcagccgt    480
 acgtcgggcg tgggtgatgt tcagttgttc ggttcacagt acgcgatgcg tatctggatg    540
 aacccgaatg agctgaacaa agtggagaga aatagtagaa ggcaagatgt aggagagaga    600
 gatatttcct caggctccag gaaagtaaat aaggagtcaa gagaggatga ggaggtgacc    660
 tga                                                                  663



      <210> 2323
      <211> 264
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(264)
      <223> n = a,t,c or g


      <400> 2323
 angaggatca nactatgagc gtgagactac gattccatca atgcctgtca agggcaagta     60
 ttgacatgtc gtcgtaacct gtagaacgga gtaacctcgg tgtgcggctg tatgcctgct    120
 gcggattgct gctgcgtcct gcttatccac aacattttgc gcacggttat gtggacaaaa    180
 tacctgatta cccacgccgt gccggcacgt taaccgggct gcatccgatg caagtgtgtc    240
 gctgtcgacg agctcgcgag ctcg                                           264



      <210> 2324
      <211> 921
      <212> DNA
      <213> Homo sapiens


      <400> 2324
 atgctcgacg actacggcgg tagcctgagc gaactggcac gggagcaact gcccgctgcg     60
 gaacaggcgg cgctggcgca gcttgctgcg cgttcgcttg cgccagtacc ggatgacaca    120
 ggaggagcag ggatgagcaa cgacacgcca tttgatgcgt tgtggcaacg aatgctggcg    180
 cgcggctgga cgccagtcag tgaatcccgt cttgacgact ggcttacgca agcgccagac    240
 ggcgtggtgt tattaagcag tgacccgaaa cgcacgccag aggtcagcga taatccggta    300
 atgattggcg aattactgcg cgagtttccc gactatacat ggcaggtggc gattgctgac    360
 cttgagcaga gcggacgcat cggcgatcgc tttggcgtct ttcgctttcc tgccacttta    420
 gtgtttaccg gcggaaacta tcgcggcgtg ctgaatggta ttcacccgtt ggcggaactg    480
 ataaacctga tgcgctggct tgtcgaaccg cagcaggagc ttcatcaacc gctaaccacg    540
 gtacagaacg ccaacgactg ttgctgcgac ggcgcatgtt ccagcacgcc aactctctct    600
 gaaaacgtct ccggcacccg ctatagctgg aaagtcagcg gcatggactg cgccgcctgt    660
 gcgcgcaagg tagaaaatgc cgtgcgccag cttgcaggcg tgaatcaggt gcaggtgttg    720
 ttcgccaccg aaaaactggt ggtcgatgcc gacaatgaca ttcgtgcaca agttgaatct    780
 gcgctgcaaa aagcaggcta ttccctgcgc gatgaacagg ccgccgaaga accgcaagca    840
 tcacgcctga aagagaatct gccgctgatt acgctaatcg attcttctta tttcccacat    900
 ggcacagagc ttgccttcta g                                              921



      <210> 2325
      <211> 547
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(547)
      <223> n = a,t,c or g


      <400> 2325
 ncctctggtt gaagtttgga gttacaagcc ctaaaggggc ctctaatttc catgtccccc     60
 cgccccccat gtttgtgggc ctccgccctg ccccagggct tttccggtgg gacaannnnn    120
 nnnnnagccc caggtggcca caggttttcc ctgaagccct gtttgtcctc ctcccaggct    180
 gtactggggt cccgggactg agcggcactg ggtggagact cactacaggg cttttctccc    240
 atcgcagcac ctgagcagcc ccgtgactgc ggcctgaggt ttgccccacg tgcgctgtgg    300
 gccaggcaga gcgccaggtg cacccaggat gccttcatct tcaccgccgc tccagagcca    360
 gggactggtg actaaccctg tatccacgag atagcaggct cagtacggtc agggacttgt    420
 ctgaggtctc acatccaggg ttgttcgccg tccccgggct cagtgtctcg ctccccgcct    480
 gcggagtgga gtagttttga gatgtgagca tgccatctcc ctttccacgg ccccctcntn    540
 cnnnttc                                                              547



      <210> 2326
      <211> 1020
      <212> DNA
      <213> Homo sapiens


      <400> 2326
 tttcctcttt ctccctcatt cttatctttc ctctttctct ttccctttaa atccttccct     60
 ccgtcttcac ccaccttcac ctctgtcttt gtgaaatcta aatctgcttt actctaagcg    120
 tttcaataat tcaggctcca cagtccctca ggtgccccca gccctgctcc tatactcccg    180
 tggtttccca acagatctgc ctgctgcggc tgtgctccgc tggcctctgg ggctcccgct    240
 ccctgggagt cagctgggca tcatgttcct gcaccttttc agaagatgac aaagtgcagg    300
 cttgcaaggg tgaatgtggc tgctagagag gattcaccta aaattcgaag ccaatccgag    360
 ggaggagctc aacgagccct gggtctaggc ccatgcagtg tgtccgaagt tctgatgagc    420
 tcttccggaa ggtgggccat aggccacgat gcccatctca cttggggttg ccctcctgca    480
 tggcaaccct ggcatcttac ttcctcttcc tcagcccctt tgtgccctgt ctgggctggg    540
 cctcgaccac ggacatggtt gggggcatgg gctctgcact gaggctgctc caggtagagt    600
 ccagctcaca ctctctggct acgggagttc atgcctctgc gccttcatct cttcaactgt    660
 caaagggaat aataatacct acgtcatggg gtcctttgac atctacagag cttaaaacag    720
 tgtctgacaa gcacttcata aacgttaggt attggtacgt gacccaagtc agcctgccca    780
 acctttctct gtctcctttt cccctcagaa acacagggat gagaaactct atttccttcc    840
 taagggagtt tctgggggat cagagctgag aggcaggccc cagccctacc ttccctgccc    900
 cgtctcacct actctttgcc catgggggca cttgtctctg gccccacctt ctgtcccccc    960
 aactgcctgt gagtcctctt cggagctctg gcccagcctg agctggacat gggcggagag   1020



      <210> 2327
      <211> 3563
      <212> DNA
      <213> Homo sapiens


      <400> 2327
 gccagataac cccccgcccc acataaccag ctgcgctcct acacctagca ggccggctca     60
 catcaccctt taacgcacac tatattcaca cacacacttg tgcacagtct tgaatgtgtg    120
 cccacacatc tgcctgcaca cactcatgtg cccacatgtg aatcacttgg aagtgtacac    180
 aaaaccaaac ccacagcaca gatgggcaga caggtgagcc tcgtgcagca tgtgacactc    240
 ccacatgcac aagacatgtg tgcagaggca tatcacacac gcagaagcac tcccgagaac    300
 tgccttctcc cttccagcct aggggcccct gttcccccac aaccgggccc agccctggag    360
 ccccctccag cactcctctc ccacccccac gctccccaag agcagcagat gtaggtctcc    420
 cggctcccaa acctctgaga tgctgctctg tctgaaatca tcatataaat aatcattttt    480
 taatacaagg gggtgggggt gtcaggcaag ttccatgaaa ttgtgaatta gccgctgctc    540
 caaataaatg cctgcttcgg cccgagagca gccgcgctgc gcccgctgcg cccccaataa    600
 tcgtgtgttg ggtatctctc cattgttccc tgggccatta gtcaaagggc aaattagaaa    660
 caatttcttg acgacaaaaa ttgactctta attcttccca ccagaggcgc agggggacaa    720
 gtccagaggc caggcctgag gctggggctg gcggcaggag gggtaggcgg agtagaggtg    780
 gggtagaggg tggggatcta agatggttca cagcacagag acctccctca actggagggc    840
 agcagcagct cacccccacc ccaaaatcag tgttccagag gacagctggg ggcagggggt    900
 taggaacaat cccactccct cctggaagag gtcctgaccc cccaccccac ccatctgcct    960
 gtacgggtcc ctctgctatc gactggggcg agttcttttc atgagggcct tgcctggtgc   1020
 ctggagggaa cagggtgtgg gggaaaggtc tgtgtgttcc cccctcacct cccctgctca   1080
 gcggtgtggc ctctggctct ggggaggatc gggaagcccc agggtccgtg ccttggagtg   1140
 gggggacagc cttttctctg ccacagcttc tgcctttggg ggcttaccct tcctaggagc   1200
 agaactgttg tggaggggaa gaggacggtg aaggttccga agggaagggg gctgccccca   1260
 ctgaaaacga agcttccagt cacagcccct tcattattta tcaggaccca ggggatgagg   1320
 tggcagggga gggggctgca tggagggagt gccctcaccc tcgtccccag cgcctgcccc   1380
 ctcccgacca ggcctgggct gaggcccagg gtaagggggc tgaggcaggc cacagaggag   1440
 caagacttgt caggggccag acctgggtag gaggattgtc ctccaggcac acacggcccc   1500
 cagcccccca gcctgtcgaa ctgggctctc ccagaaggtc cccggctcca gcccaagcag   1560
 ggagccaggt tgggggtgtg ggaaggcaga agtcccaggg atcctggggg aggctcaggt   1620
 tgtacctgca ggccacagtc tcctcgacag acctcggacg aggttgtaag tgttttaaag   1680
 aaactagagc agcagagaag agagactcag aagcccgtgg cacggctttc tcggcgtccc   1740
 ctccagcgag ggggtctcca ttgctgcagt tgccggtttt gtccaaccag gtcaggaggc   1800
 tgcccggccc cctccccact ctcaaagttg cttgttaaac acagagtcgt aatttgtggc   1860
 taaatataac tagtgtgttc tcacggaaag tataattcag ggtgctcatt gtatgaggtt   1920
 atcaacaaga cccatctggg ttaaattaaa gtgattttca taaagggcag aagcgcccct   1980
 ttgcctggtt tcccctgcct ttttattagt gacagtgtta ttgttgcaat tattagaggg   2040
 gatcaaggaa ggtgggagtt gccagggacc cccaggctga ggagggagcc tcccagcccc   2100
 cctccactca ccattgtcct gctgcccctc cagccccctg gtcactgtca cctctgcggc   2160
 tggagggctg gagaaaggcc caggagccca gggaacctcc accatgccag gctgccttcc   2220
 ctaaaggccg gctccttccc cccaggcagc cagtctgggg gtggacctgg aggggcaggg   2280
 ttctctggga atctctgggc caagggatgc cctttgggga tctgctggaa taaagagtaa   2340
 tcggttttcc ttgcaggagg ttgacccgaa acagccctcc gtcttcctgc ccatgaggat   2400
 gaggacagga agccagaccc gggagagaaa gcccagatca gacagatggg ggttgggagg   2460
 gcctagtggc tgaaactgcc ctgcttgggg acaatgctca ggcaggacca atccaaacga   2520
 gggcactgct tatgtggtcc ttccggagca tcctccaagg cagagcctgg cttcgggccc   2580
 tccctgcaag gacacctgcc tccactccct gccagaccag gcctggctgc agaggcggag   2640
 gggcggcagg gctgcctgtc tccactgttt ggcggtgttt acacgtgtcg ctgtcagggt   2700
 gtctggacag tgggggtcgg gggcctcccg ggcccagact tccccaggcc tattctcaca   2760
 ctggtgagag ggccctaggg gaagggtgtg ggctgggtgg cggggccagg ccagctgaga   2820
 cctacaggac cgtggagcat ttaggtctcc cacccaactc cacccggtcc tctgagcatc   2880
 agttacagag cccaggcagc aggagggcag ggcccagccc cttatcaccc atcctcaagg   2940
 caggcaggaa ccctgaaggc agcttccacc aggggttccc ttagccccca ccctccaaaa   3000
 gccccagacc ctgccaggcc tcaccctgcc agcatcgtgg ccccagctga cggctcccaa   3060
 gggcaggtgc tggcaacaca agcaggagcc ctcggggcat cccgcagggc acacaccagg   3120
 tcgccctggg ctccccaagc acctcccaga cccagccctt gggtgggtcc tggcccacaa   3180
 acccccacgc cctgcccctg agatgagccc caccgcccac ctgccctcca gccctggaga   3240
 cctttctccc ccttgcccat ggctcccatg gggaggctgc aggccctccc tgggctggac   3300
 cagaggggac agactgtctc tcccctgcga cttctggggg cactggagtc cttggcctgg   3360
 ttaccttcag catttatagc cctccagtga gttattcctc ggagttctca cagagcagca   3420
 tgcgcctgcg gcaaagccct cacctccagc ccctggacca cctgactgct gcctcccgcc   3480
 tggcgccaaa cacggccacc gcctcttttg ttaacaggac agttgatcca ttaaattaaa   3540
 aatcattcaa tagaaaaaaa aaa                                           3563



      <210> 2328
      <211> 523
      <212> DNA
      <213> Homo sapiens


      <400> 2328
 cggccgcagc caaccgcaaa cgcgcggcct actacagcgc cgcggggccc aggccgggag     60
 ccgaccggca cggcaggtac cagctggagg atgagtctgc gcatttggat gaaatgccac    120
 taatgatgtc tgaagaaggc tttgagaatg aggaaagtga ttaccacacc ttaccacgag    180
 ccaggataat gcaaaggaaa agaggactgg agtggtttgt ctgtgatggc tggaagttcc    240
 tctgtaccag ttgctgtggt tggctgataa atatttgtcg aagaaagaaa gagctgaaag    300
 ctcgcacagt atggcttgga tgtcctgaaa agtgtgaaga aaaacatccc aggaattcta    360
 taaaaaatca aaaatacaat gtgtttacct ttatacctgg ggttttgtat gaacaattca    420
 agtttttctt gaatctctat tttgcagtaa tatcctgctc acagtttgtg acagcattga    480
 aaataggcta tctctacacc tactgggctc ctctgggatt tgt                      523



      <210> 2329
      <211> 434
      <212> DNA
      <213> Homo sapiens


      <400> 2329
 ggagcagttt ctgcgccggc agattgcctc agaaaaagaa gagattgaac gcctcaaagc     60
 tgagattgct gaaattcaga gtcgccagca gcacggccga agtgagactg aggagtactc    120
 ctctctcctt ctgcagttct aaaccacagt ctataagccc gagtcaccag gacggcctgt    180
 ctggccacag acaggggctg cctgtggagc ctgcccaccg gcccccggca gtgcagtcca    240
 gcggggagga ggctgcccgt tcctgccagt tcctcactgc ggggaccagc aaaggccttc    300
 tcactgggtt ggtcaaaggt agtcaccttg gcctggtgca tccacagagg atgttgttca    360
 aaccaaaaat cttttaaacg actgaccttc cttaaaaaca gaatgactcc caatgcttgt    420
 tgggctagaa tgac                                                      434



      <210> 2330
      <211> 402
      <212> DNA
      <213> Homo sapiens


      <400> 2330
 atggaaatgg gggcttcgta gttcattggt taaacaacaa ggaatttcat tttacatcat     60
 ctacagaagt atttatgcat caattacgaa agctttctga taagcaggta gatcatgaaa    120
 atgatgatgc agatagagaa gatgaggaac attcacagga ggatagagaa cggggtttac    180
 atatgaaatt agaccatgat ttatccctgg atagagaatc tgaggcaggt acaggatcct    240
 cagaacatga agatggagaa agagaaggaa gtcctagaac ctactcacga cttagtgtac    300
 caatgccact gcctacggtt ctgcttgatc ggaagattga aacgctgcta actgaatgga    360
 ataagaatcc tgatatgctt tttacaatac accctatgta tt                       402



      <210> 2331
      <211> 1104
      <212> DNA
      <213> Homo sapiens


      <400> 2331
 atgggaacca ctgtaactga cattccactt gcagacatgc taggagtgcc ccggcgtctt     60
 tctagcctcc gcctccaggc gggtgaggag gtgacacctg agaattcctc cctctcaccc    120
 ctgaccctgc cggaaagcga aactgagatg cgggcattgg gccctgggaa gcgtggggaa    180
 ggggaaagga gaaagccagg cctgtactca gatcttcgca gagcggagca gcggccggag    240
 cgtttggcgg actctgcgtg gacttggagc tcacagcgtc ttgcgacttg gaagcggatt    300
 cagaggacag gacagaacac ttgggcaagt gaatctctgt ctttcgaagc cctggccaat    360
 ctaccagcca acatgatgca gctacctggc catttctcca catttctggt gagggcccca    420
 cacccagccg cagaaaagcc cctcctgcat tccatcctca cacacaggcc tgtccatcca    480
 cttgctactg tcacactctt gccagcagaa gaggcccctg taatggccga tatcaccgcc    540
 cagtctatcc tcaccccaca gctatgcagc gggaccctcc tgctggccca cgtggctgcc    600
 agagcccatg ctggcactac actccagcat gtcggcatcc ctgcgggcga cactaccggt    660
 gacatggcca gcatgaccct cctccctggc agtgacactg ttgatttgga agccctggcc    720
 aatctactag ccaacatgac gcagttacct ggccatttct ccacattcct ggtgagcgcc    780
 ccacagccag ccgcagaaaa gcccctcctg cattccatcc tcacacacag gcctgtccat    840
 ctgcttgcta ctgtcacact cttgccagca gaagaggccc ctctaatggc cgatatcacc    900
 gcccaggcta tcctcacccc acagctgtgc agcgggaccc tcctgctggc ccacgtggct    960
 gccagagccc atgctgacac gaacctccag catgtcggca tccctgcggg cgacactacc   1020
 ggtgacatgg ccagcatgac cctcctccct ggcagtgaca gaggctatgg gtacctgaga   1080
 tgtaccaggc aggttgagac atag                                          1104



      <210> 2332
      <211> 900
      <212> DNA
      <213> Homo sapiens


      <400> 2332
 tttcgtggta tatgcataag aaaaatgaag tgcatgaact ttatattcag aaagaatggg     60
 tttgaatcct gagtcttgtg cttgttagct atgtccttag tcaaattatt taacttgttg    120
 gttttctcat atagaagagg ggcagtaata acaattaaaa tagaggtaaa gattaaagtg    180
 acatatgtaa agtgccaggc acatggtgag aggctaataa atggccacta tgactactca    240
 gcctgccacg tcataaagct gatgttctgt gcagaggaaa agaaacctca tcaatagtaa    300
 gagccacatc tatcaggaga aagctgtcag tctctgaagc atgttctttt ttcaagccca    360
 gagagactcc acttcaccac cttatcttgc ccaaggctcc aagcgtatgt tcctgatgct    420
 tctttaaatc cccaaagtgc gaaggcatgc ctgatatatt tgacattcag taaatattaa    480
 tgaatgatga cttttctgtg gtgaaatgca ccccactttc actgttcctt tcggatttgc    540
 acttacttgg atacttgtgg atgattctga agagctggtt gttcacatct gtctctgtta    600
 tgtggcagag atatttctca tttaacttga cagggtattt caagatggag aacaccctgt    660
 agaagccatt catctggctc tccaggaatt ccacgatgct gggggttgct aagtcccctt    720
 tctgtccggt ccagccatgg cacaaatggg cctgagggac ctagcctttt ggaaaggcct    780
 gtggcgccca tccttctaca tcaattctgg gaaaattgga cccgggggca tttcaaagag    840
 cttctaatta taagcttaat tgtacttttc acctcgttgc actggggggg gaagggtgcc    900



      <210> 2333
      <211> 436
      <212> DNA
      <213> Homo sapiens


      <400> 2333
 aacaggggag aaggtagtac caggagaggt aaacccaccc aatggccctg tgggggaccc     60
 actgagcctc ttgtttgggg atgtgacatc cctgaaaagc tttgattcat tgacaggttg    120
 tggtgacata atagcagaac aggacatgga cagtatgaca gacagcatgg cctctggggg    180
 ccagagagca aaccgagatg ggaccaagcg aagttcctgc ctggtgacct accaaggagg    240
 tggggaggag atggccttgc cagatgatga tgacgaggag gaagaagagg aagaagaggt    300
 ggaattagag gaggaagaag aggaggttaa ggaggaggaa gaagatgatg acttagaata    360
 tctgtaagaa actgcccaaa tgtatccacg gccctgtatg cggccggtct gaggatctag    420
 ctacgaggcg gtcatt                                                    436



      <210> 2334
      <211> 411
      <212> DNA
      <213> Homo sapiens


      <400> 2334
 cggacgcgtg ggtcgaatgc taacagccac agtacatagc acctttaatg gcaaatttcg     60
 atcccagtgt atccagaaat tcaactgtca gatattttga taatggcaca gcacttgtgg    120
 tccagtggga ccatgtacat ctccaggata attataacct gggaagcttc acattccagg    180
 caaccctgct catggatgga cgaatcatct ttggatacaa agaaattcct gtcttggtca    240
 cacagataag ttcaaccaat catccagtga aagtcggact gtccgatgca tttgtcgttg    300
 tccacaggat ccaacaaatt cccagtacgt agaagaaggg cagtcgcaat gagtgagcct    360
 ctgtgggggt aaatttaaag gagattggtc tatggcagct gtacctgaat t             411



      <210> 2335
      <211> 417
      <212> DNA
      <213> Homo sapiens


      <400> 2335
 ctgaaagtgg agacggacgg caggatggat tcacttggcg acatggcggg gagctgggaa     60
 gacggacacc gacctaagtc aatgttagtc taccactgta cgtctggtaa cctcaatccc    120
 tgcaaccgga gcaaaatgtg attccaggtc ttggcaacct ctgaaattcc aactccattt    180
 gcgagagctt tgaggaggcc atatgctgat ttcaccacaa gcaacttcac aacccagtac    240
 tggaatgcca tcagccagca ggcccctgcc attatctgtg acttctatct gtggctcatt    300
 ggaaggaaac ccagctaccg aaggaagata ccctcatcaa cccaatttta caaatggaga    360
 aatagaagct cagggaatgt attgcgggcg ctctggagga tacacgctag gtcctat       417



      <210> 2336
      <211> 1213
      <212> DNA
      <213> Homo sapiens


      <400> 2336
 atggaccccg ccgggcgcgc ccggggccaa ggggccacgg caggggggct gctgctccgg     60
 gctgctgcgg ccgccaaggg tctcagggaa gacctgtggg gcgcggccgc cctggccttg    120
 gaggagcctg tcccggatcc cgaagcggga gggtcttgga gaggaggaca cagcagttgc    180
 cggacacgag ctcctactcc caaatgagag aagctttcag aatgctgcta aaagcaataa    240
 tttggatctt atggagaagc tgtttgaaaa gaaggttaac attaatgttg tgaacaatat    300
 gaaccgcaca gccctgcatt ttgcagtggg gagaaatcat ttatctgcag tggatttctt    360
 gcttaaacac aaggccaggg tggatgttgc tgataagacc agaatgagag agcttctctt    420
 ggaaatcttt ctgactgtgc ccagggcaca gttccatgat ttgcactgcc ttgagtccaa    480
 gttggaagac tgtgaaatga gagacacatt aagacacatg caggctgtgt atagggagac    540
 taatatttta actcacacag taacttgtgt gagattggga gccctttctt accttaagac    600
 catggcatgc cgtccccaac agaacatctt gagtgataag aacatggact ctgttcttac    660
 cagctacatg aacctgggaa agctgcataa cctctctgtg cttcagtttc tctatctgaa    720
 aaatgaggat aagaatagca cctacgttaa tttaattctc agtgagcgaa ttcctaccct    780
 catttttcag atacagaaac cgaagtacag agaggttatg cagcttgccc agatgttagt    840
 ggttctggct ttaaccctct tctcattcac agtcgtagtc cttaactcta ttagggctat    900
 ggtcccctct gaacgcatat ttaaagcgaa agatcttctt tctagaaaaa tacacattca    960
 catttatgat aaaaatattg catacgagtc ggcagttccc attatgccag tgattcctca   1020
 aactggatct ccaacttata cctccagtgc ggcgctccca caatgcttaa ctccaggaaa   1080
 caccattcac agtgtagcca ttgtgaatgg cagttcttgg agtagcgcac tacgtagcca   1140
 gtgtgaccac agactgcata cttgcagctt taccctagtg cctcagaggc atcctcacac   1200
 ccagctcatc tga                                                      1213



      <210> 2337
      <211> 334
      <212> DNA
      <213> Homo sapiens


      <400> 2337
 tttcgtgcta accgtacagt gaaggatgcg cacagcatcc atggcaccaa ccctcaatat     60
 ctggtggaga agatcattcg aacgcgaatc tatgagtcca agtactggaa agaggagtgc    120
 tttggactta cagctgaact tgtagtcgat aaagccatgg agttaaggtt tgtgggtggc    180
 gtctatggtg gcaacataaa accaacaccc tttctgtgtt taaccttgaa gatgcttcaa    240
 attcaacccg agaaggatat cattgtagag tttatcaaaa atgaagattt caagtgagtg    300
 caatgttcac tagctaatat aagaggcatg tatt                                334



      <210> 2338
      <211> 1794
      <212> DNA
      <213> Homo sapiens


      <400> 2338
 atgcaatgct tcctatggaa cttggatgtg gcccgcttcc agagccacta ccagtgggat     60
 gctcacgctt ctcattgttt aagtgacaga catgtatatc aactgttcct gatatatggt    120
 aactgctcaa tcaatgtcat caacacctcc accaccatca ccatcaacac taccatcatc    180
 accatcacca ccaccaccat taccacaacc actaccacca ccaccaccat caccaccaac    240
 actgtcatca ctatcatcac catcaccacc acgaccacca ttagtatcac catcaacact    300
 accatcacca caaccatcat cgccacaacc actactgcca ccatcatcat caccaccatc    360
 actaccatca ccaccaccac catcaccacc attaccatca ccatcaccat cagcaatacc    420
 atcactacca ccaccatcac cacaaccact gccaccacca ccaccatcat caccaccacc    480
 atcactacca tcaccactat taccaccacc accactatca tcatcaccat catcacctct    540
 atcaccatca ccaccaccac catcaccacc accatcacta ccaccatcac ccccaccatc    600
 accaccacca ccaccacctc cacaaccacc atcaccacca tcatcaccac tatcatcacc    660
 accattatca tcatcacaac catcactatt accaccatca ctgtcatcat taccactacc    720
 atcatcacca tcaccactac taccactatc attaccacta tcaatatcac caccatgact    780
 atctttacta tcaccactac caccatcacc atcactacca ccatcatcat tccaatcgac    840
 ttaaaccata ggacaatgct tttctttggg atgtggcatg tggctccttg tacctaccta    900
 gcacttgcag gaaacacctt aatggcatgg cccctgatgt ctgcgtccag caaggcctct    960
 ggtggtgtca gcatgtttgt gtggaggaat gtggaacctt gctctgtggc tgtgttctcc   1020
 tggtactctg tccccttcct gacccctccc tgcagccgcg tgaggcccag caacctgcca   1080
 gtcactcagt ggcctccaac cagagcaaag aacctgccaa gtcggcagct gttgctcacg   1140
 agtgtccacc aggcccagtc cctcagtgcc ctgtgcaagg aacaggactc atcttctgag   1200
 aaggatggac gcagccccaa caaatgggac aaggaccaca tctggtggcc catgagtggc   1260
 ggtcacgatc ttcagcaagc ggcaccaggc cctggcaggg cgcaccaggg tcacccctac   1320
 caggataact ggaccatcag ccagatcctg agcgagcggt ggtacaccct ggggcccaat   1380
 gagatgcaga agtaccacga cctggccttc cagcacatgg ccggtgagga catagcgagt   1440
 gacgaggagc acatggtcat ccatgaggag gagggggtga tggtgtcatt gctgatgacg   1500
 gctttagcac cactgacact gatctcaagt tcaaggattt ttggcaaagt ctatggtccc   1560
 accccgtcct cctcctacac atactcggat gcttcctcct caaccttggc acccacctcc   1620
 ttcttactgg gcccaggagc cttcaaagcc caggagtctg gtgaagaagc cgaggacggg   1680
 ctcagggaac tggagaccga gaaggcgctg tcctcttcac tgcacgcgcc ctggaccagt   1740
 gctggccctg atcatgcagc tcttccaggc ccactgcttc ttcctgtcca ctag         1794



      <210> 2339
      <211> 2581
      <212> DNA
      <213> Homo sapiens


      <400> 2339
 ctgaggactc cggacactgc ccatctctaa gataagaacc tggaaagggg actctgttgg     60
 ccattggaaa ttgcagaata atgtctcagg tgacatttag tgatgtggct atagacttct    120
 ctcatgaaga gtgggcatgc ctagattctg ctcagaggga cttatacaag gatgtgatgg    180
 tccagaatta tgagaacctg gtctctgtag caggtctttc tgtaactaag ccatatgtga    240
 tccatgttat tggaggatgg aaaagagccc tcggatgatg gagaaaaaac tgtcaaaagg    300
 tatgattcca gattgggaat caagatggga aaacaaggaa ttatcaacaa agaaggataa    360
 ttatgatgaa gattcacccc aaacagtaat aatagaaaaa gttgtaaaac aaagttatga    420
 attttcaaat tctaagaaga atttggaata tatagagaag ttggaaggga agcatggaag    480
 tcaggtagac catttcagac cagcaattct cacctctaga gaaagcccca ctgcagacag    540
 tgtttacaaa tacaatatat ttagaagcac ctttcattca aagtctactc tttctgaacc    600
 acaaaaaatt tctgctgaag ggaattcaca caaatatgat atattaaaga agaacttacc    660
 aaaaaagtca gttataaaaa atgagaaagt caatggtgga aagaaacttt tgaattctaa    720
 taaaagtggg gcagccttca gccagggcaa atctcttacc cttccccaga cttgtaatag    780
 agagaaaatc tatacatgca gtgaatgtgg gaaagccttt ggcaaacagt caatcctcaa    840
 tcgccactgg agaattcata caggagagaa gccctatgaa tgtcgtgaat gtgggaagac    900
 ttttagccat ggctcatccc ttacacgaca tctgataagc catagtggag agaaacctta    960
 caaatgtatt gaatgtggga aggcctttag ccatgtctca tcacttacta accatcagag   1020
 cactcacact ggagagaaac catatgaatg tatgaactgt ggaaagtctt ttagtcgtgt   1080
 gtcccatctt attgaacatc taagaattca tactcaagaa aaactctatg agtgtcgtat   1140
 atgtggaaag gccttcattc ataggtcatc tctcattcac catcagaaaa tccatactgg   1200
 agagaagcct tatgaatgta gagaatgtgg gaaagctttc tgctgtagct cacaccttac   1260
 tcgacatcaa agaattcaca ctatggagaa acaatatgaa tgcaacaaat gtctgaaagt   1320
 ctttagtagc ctctcatttc ttgttcagca tcagagtatt catactgaag aaaaaccctt   1380
 tgaatgtcag aaatgcagga aatccttcaa ccagcttgaa tcactgaata tgcatttgag   1440
 aaatcacatt agattgaaat gtgatttcta tctaatgaat gccatatatg tgggaaagcc   1500
 tttagtcata ggtcatccct gcttcaacat cacagaattc atactggaga gaaaccttac   1560
 gaatgtatta aatgtgggaa gaccttcagc tgtagttcaa accttaccgt acatcagaga   1620
 attcatactg gagaaaagcc atataaatgt agtgagtgtg ggaaagcttt tagcaaaggc   1680
 tcaaatctta ctgcccatca aagagtacat aatggagaga aacccaatag tgtgggaacc   1740
 cctgcagcct gtagtctcca ggcaggcctt gggccaccag gctggagaga gccgcggcca   1800
 cactcagcgg tgcaaggtga cccggctgtc ttcctggcag gtcctcgtgg gagcggctgt   1860
 cccttgttca ggggcccggg accgcgtccc cgtcccccga catgtccccc aagcatgcct   1920
 tcagggcagg gtgcagactg gaaggctgga ctggcgggga cacgcgtgtt ctgcatctcc   1980
 taacgctgtg cccactgtga catttagtga tgtggctata gacttctctc atgaagagtg   2040
 ggcatgccta gattctgctc agagggactt atacaaggat gtgatggtcc agaattatga   2100
 gaaccttgtc tctgtaggtc tttccataac taagccatat gtgatcacat tgttggagca   2160
 tgggaaagag ccctggatgg tggagaaaaa actgtcaaaa ggtatgattc cagtgttgga   2220
 agttctagcc agggcaatga ggcagaagaa cgaaataaag ggtattcagt taggaaaaga   2280
 ggaagtcaaa ttgtccctgt ttgcagatga catgattgta tatcttgaaa accccattgt   2340
 ctcagcccaa aatctcctta agctgataag caacttcagc aaagtctcag agataccaaa   2400
 atcaatgtac aaaaatcaca aggcattctt atacaccaac aacagacaaa cagagagcca   2460
 aatcatgagt gaactcccat tcacaattgc ttcaaagaga ataaaatacc taggaatcca   2520
 acttacaagg gatgtgaagg acctctttaa ggagaactac aaaccctgct caacgaaata   2580
 a                                                                   2581



      <210> 2340
      <211> 606
      <212> DNA
      <213> Homo sapiens


      <400> 2340
 tcaaatcatg ctaccaatgt aggaagaatg tacttcccat gtcctgttgc catgaggtgg     60
 aggttgagag acaccaggat tgtgggctag gaggtcggta aagagcagag ggctctttcc    120
 tgggctgcct agtcctagca gggcatctgt tagatccctg ctgctgctac ctgcatgggc    180
 agccttcttg gagggaatag tagataccag acccacagca tggagagcat ttccctggac    240
 cctctttctg agtgtcttct gccaattttt ggattttcca gaaacgtctt tggattccca    300
 aaagttgagt ttagatactc ccagtttttg aatttcattt ctctttagaa ttattgccat    360
 tttatataag aaacttgaac atctgcagat tttagtatcc acaggggttg ggggtgtcct    420
 ggaatcaatc cctgcagaca cgaaggggac attgtactca tcagtattag ccagctctaa    480
 gtcagcacac aaaacatttg ctttatgcag ttttatccac gtcattaaca aagatgaaga    540
 ataagaagaa gataagtaca ttgaatttcc aaacatcaaa atgaaactaa gggtaactga    600
 aatcat                                                               606



      <210> 2341
      <211> 597
      <212> DNA
      <213> Homo sapiens


      <400> 2341
 tcaccaagtg ctggaagcaa cacaagcgtc cttcaatggt gaacggatgg cagggccccc     60
 agaagaccac aggaaagtcg tgtagagaag acgttcaggt gagctctggg acgaggaatc    120
 ttcagaggag gcgaagattc ctctgaatcc tccttcagag gaggcgaaga ttcctctgaa    180
 tcctccttca gaggaggcga agattcctct gaatcctcct tcagaggagt ctgggggtgg    240
 gagggcacag ggcatggggt atccaggagc caagcaaagt gttggtttcc gggagaagga    300
 ctgaggcacc ctcaatgctg cagatggggc gtcagatgtg ggggagaacg agctggagat    360
 ggacacggac atggaggtgt ggatggccct ggggaggccc cctggcagct cggcacgtgt    420
 ccagctgcac aaagcagggt cattagtaac ccactttccc cgcaggcgcc tctgcagcat    480
 gggcctggca gggctaaact gagaatccag gagcgtgaat gctctagtgt gcacctcggc    540
 cattgtgtgc gtgtgttccg gactcaccgt gaatgttcta gagtgtacct cggccat       597



      <210> 2342
      <211> 646
      <212> DNA
      <213> Homo sapiens


      <400> 2342
 acttgattca gttaaatatg actccactta tatggattct aaatataaat atataggtct     60
 acttaaaatc atctacccac ccatctcttt atctctctac ctttctatct gtctcatttt    120
 tcctgtcacc ctccatgaca atgagcacaa tagcaggagg tagtttgtat gtttgctgtt    180
 ttctcaatat ctacgacagt gcctggcaca gggtgggcat cggtatccac ggaatgaacg    240
 aatccatggc ttttgagctg aggaagaaca taatcaaaat ggtcctttga gctgaggcct    300
 tgcagagatg tactggatag agcgaaaggg ggaagctagc cccagtaggc agggaagggg    360
 aggcggggga gctatgtgtg gcccgtgttt gtggtcatga gcatctgatg taggaggtgg    420
 ccatggctgg gagggatcat acagacatga ctgatattga gaacggagga tcgatgggat    480
 ttgactactt aatttgtcaa aaagggtaaa tattcactga ccccccagca aagggaattt    540
 tatttttgga gcggaaaacc ccgcttgggc agtttgcaaa acaacgttgc tactattata    600
 gacaaagggg gggcctggac tttctttgaa gaacacaagc ctagaa                   646



      <210> 2343
      <211> 1252
      <212> DNA
      <213> Homo sapiens


      <400> 2343
 gttactgcag gagtgcctaa agggcactgc ccaagacgtg ggacatcctc agcaatagca     60
 tcatgccctc cttacggctc tccgcccaga gccgagtgcg cgttaagagc ggggtcaaca    120
 gttaccacct gaaggcggtc ttgttgcacc tcatactcct ccggcaggcc gccgactgga    180
 aggcggggca gctggacgct cgtctgcact agttgctgtg cttcctggag aagagcttgc    240
 tccagaagaa gctccacctc ttcttcatcg gcaaccgcaa ggtgcctgag gccatgggac    300
 tccctgaggc cgtgctcagg gccgagcccc tcaacctctt ccggcccttc gtcctgcagc    360
 gaagccttta ccgtaagaca ctggactcct tctatgagat gctcaagaat gccccaacgc    420
 tcattagcga gtattcccta catgtcccct cagaccagcc taccccaaaa agctgacgtc    480
 ttttacagaa tgtgggatcc tcgagctaag atgagggcat ccctcacgtt cacacccctg    540
 gtggcatctg ccagccctgt tctggggaca aggcgggctt tcgtgggagc cgtgctcagc    600
 ctgccaggaa gccaagccct acagtgcaga ggaaacagaa tttcaacggg aagctggttt    660
 gcttcatacc attgggatct gctggtaaag ctgttatttg ggtttaggga ctgatccctt    720
 gcaagttact tctggatcac catgaatggc caagatggtg gcagaacacg ctgtggaccc    780
 tgagttagag acaatgcaaa tgttggattg ggtgtaattc tttttgaatc ccagatccag    840
 tctgtacttg aatatgagca gaggatctac aagaatgctg acagggaacc gtgttaagac    900
 ccagcacccc tattcccagg agcttctggc ctgaccatct gcagccaaag cactaacagg    960
 gacagatatg ggaatgtcca cctttgatcc gcatcctgca caatagtggt cccaccatgg   1020
 ctgccacttt tttatactat ttggagaaaa gaccttgtat aaattcgagg cccgaatgac   1080
 taacgtctct gtcacacgga aatgggtact tggtggcata gagaaacaca attagccact   1140
 ttttcagcta cacttctcac tcagctgctt ctaaagcaga aagcagtggg gctcttggtg   1200
 tttcatgctg ccttatttat attaaaggaa gaattaaatc ttgaaaaaaa aa           1252



      <210> 2344
      <211> 668
      <212> DNA
      <213> Homo sapiens


      <400> 2344
 attccagggc aggggcctgg cggctaatga tggtgagtac ctcaaactgc agtggagggc     60
 tggcactctg gttcttgccc cctcatgccc cctctccacc ctctctgttc tttcctctcc    120
 tcccagggag cttcaggcca tggaggcctt gcagaatggc cagaccacgg tagaggggag    180
 catagagggc cagtcggctg gggctgcgag ccatgccatg atagaaaaga tcctcagcga    240
 ggagcctcgg tggcaagaga ctgcttatgt gctgggtaac tataagacgg agccttgcaa    300
 gaagcccccg cggctgtgcc gccaaggcta tgcctgtccc tactaccaca acagcaagga    360
 ccggcggcgg agcccccgga agcacaaata caggtcctta ggccccagga ggccagccac    420
 gggagggagg agtggcaggg aaggggtcag gcagaggctg ctcccactgg ctctccggga    480
 ggaggggagg ctggtcctgg ggatgacagg atcgcaagcc cagggcccag gggagggcat    540
 agtgaggata gctggacagt aggagcccag cttcacctcc tgcatgaatg aggaccctgg    600
 tcagaccgtc tctgaggctc caccgctcct gatcctgcat gaatgaggac cacgccacag    660
 cgtggacc                                                             668



      <210> 2345
      <211> 515
      <212> DNA
      <213> Homo sapiens


      <400> 2345
 cccacgcgtc cggcttcatc tgcccaccaa gttttaaatt gtaagaactg agcaggagtt     60
 agacaagctc gagtaagagc atcccagtca gtaggaatca tccaactgga aacagcaaca    120
 ttctttaaca gtcccattac aaaaggagaa cctggtccat actgattaac agcttgttta    180
 aattctttaa ataatttaaa aggaaaaggc tcaaatgtaa ctataatatt tccctgttga    240
 tctggggggt gtattctaac agggaattgc caagcctcta aatcgccctc tcatctagct    300
 tgctgaattc ctgcctgaat agaactaaga gcagttgctc aaggcattgc tcagtcactg    360
 gggcaactac ttttcaccca atgtcctctg gaaaagaaag atctggaggg tctttttctt    420
 caaaataata aggagggggt gcagaagggt agggatgaac ctctccctcc tttgccgctt    480
 gagctttagc tggcaaattg gcaaataaac ctgct                               515



      <210> 2346
      <211> 918
      <212> DNA
      <213> Homo sapiens


      <400> 2346
 atgagtacag ctgtggtcgt gaaggttgtg ctttgtacag tagcacctgg caggggctct     60
 gctccttcct taagctcgtg tcttgactgg aaggtcaatg gagcagaggg gagccataat    120
 aaagatctct ttgtccttac ctatggagct ctggttgccc agctgtgtaa ggattatgag    180
 aaggatgaag atgtgaacca atatttagat aaaatgggtt acggcattgg aacgcggctt    240
 gtggaagact ttttggctcg atcctgcgtg ggaagatgcc atagttattc agaaattata    300
 gacataattg cccaggacat ggagaggggg ttctgtgctc tccacataga cactgaaggc    360
 agatacgaat ggtggacaac ttccactcag ctccaatcta ctttacctcg agcagcacag    420
 tgctctgtct accaaaagca gcctgacagg aaatccctaa ctgtaggcca aaagattgaa    480
 gtaggaaacc caggtattgg aacggaacag agtccccagg gtctagtgag atttgcaacc    540
 caggcattcc ttaccacgca cagagctgaa gggttgcagc aaagccaagt gaaaggctca    600
 gttattcacc tgaagagtca ggacaaatgt ggagaacaca ggttcacaac aaaccaggta    660
 gaaacaggag acccggtcag agagagcagt tctcagcaca gtgtaggcag gggaggaccc    720
 aaggatattc aaatccaggg tgccaatgtc ccagttcggc agtgtaacct cctctggagg    780
 atcacccttg ggccactgga gactcctcac ctggagtttt ctggggaatg ctctctcttg    840
 gctgcaatgg aagccccaga gcacacttgg gatcaggaga aatctgacat tccagagccc    900
 ccccataggt caagctga                                                  918



      <210> 2347
      <211> 642
      <212> DNA
      <213> Homo sapiens


      <400> 2347
 ggaggaaagc tgtaagatga aaagacatct tgcagtcctt gcagcgaagc atagctaaat     60
 gtgtgcatgc ataagagaag ctcttgaatc cccaaaccac ctcattcttt cttcagcttt    120
 tacagaagaa gcaatggtat ccaaaatctt tcccctgttg tctgccttcc caagggcttt    180
 taccagcagc aagagtgcag aagtgtctgc tagttttgag aaatgtgtct gggtctcctt    240
 ttcctttcct tataggcttc cctccaccaa tcctggagct aaaagaatca tacccattgg    300
 gcagggactg acattcaatg tgaacctgct caggggcatg tattaacatc acccagccct    360
 actcttcggg cttcagggag ccccagacct ccctgctggg gagcctgcct ggcttctact    420
 tactgccagg gaggaagatg atggctgaaa tttctcctgc taggcctctt tggtggtgca    480
 gggtcagcgg ttgatgaaaa ccactgtgat ccagctccat atcctatgtg agtggaggcc    540
 tgatctttct tgtcaaaata aggattatta ttttcccatt tctagagagc ttcttggcca    600
 gcagtgcttc attattacag ttgccacatt tttctcatta aa                       642



      <210> 2348
      <211> 1437
      <212> DNA
      <213> Homo sapiens


      <400> 2348
 atggttggag aatgtggaac taagctggag gtcatgcaag tacacttaag caatccccgt     60
 gatgagttag aaggggagct cagaagcatc agggtgacaa tgggacaagt gtgggctctg    120
 gttcattcca ccttggaacc ttttcacact aatgaagagg aggaaggatt atataacaaa    180
 gtaacagaag aggtgacaga gcaggtttgt ttgccagcta aagctaaagc agcaaaggaa    240
 ggagaggttc atccctaccc ttctccattc cctcattatt ttgaagaaac agagtggcct    300
 gaccctccag atctttcttt tctggaggac actggaggag atcctagtct cactagccat    360
 tggcaattaa caaaggaggc tgaggcagag ttacagctga ttgaaaagca agtccataaa    420
 gctcaaataa atagaataga tccagagaag attccagatt tgctaatttt ttcaactcag    480
 cattcaccta ctggtgttat tgtccaagaa caggacttag tagaatggct ttttcttcca    540
 catactaatt catggactct aactccttat ttggatcaaa acgctactat gataggaaat    600
 gagagaactc agattgttaa attacatgga tatgatccta gaaaaattat tgtcctcctc    660
 atgaaggcaa acatacagca agcttttata aatggtctta cttggcaaac tcatttagct    720
 aactttgtgg ttattctcga taatcatttt cctaaaatga aactgtttca atttttgaaa    780
 ttaactaatt ggattctccc taaaataact aaatttaaac caattaaagg tgctgaaaat    840
 gtcttcacag atgggtctag taatggtaaa gcttcttatt ctggctcaaa aggactgagt    900
 caacagctga tttggatatc atcaagaaac ctgaaacctt atcatgagtc agatgctgag    960
 gaagagattc caggaagaac ccaaggaacc cctggttgca gtcatgtcga gactgacact   1020
 gaggaggacc ccaactgtca tgagcagcac ccattgaaca cagccaccca cctggggaca   1080
 gatcaagaag ctgtcacaga tggtggaaga aaacctgagg aaagagggac aaccagtcac   1140
 aatgagtaat ttggtgatct atcacagtga tgatcaccat tgccatgagt attccttcaa   1200
 caagggctga cacagagaac aattatactt attgggcata tttatcaatc ttgtctggca   1260
 ataatgccta gatgatttca ctctatggca cagttacaca tgctttctga tctcagtatt   1320
 taccataata aatctgctcc tataattgag gcataccacc ctcaaaaacc tatttgtaaa   1380
 caaaatagaa cctggccaga aataatgaac aacttgttta gtaagattgc attgcag      1437



      <210> 2349
      <211> 1498
      <212> DNA
      <213> Homo sapiens


      <400> 2349
 gcggcccgag cccagctgcc ggccgcgcag cgaataccag ccctccgacg ctcccttcga     60
 gcgcgagacc cagtaccaga aggacttccg cgcctggccg ctgccgcgcc gcggggacca    120
 cccgtggatc cccaagcccg tgcagatctc tgcggcctcc caggcgtcgg cgcccattct    180
 cggggcgccc aagcgccggc cgcagagcca ggagcgctgg ccagtgcagg ccgccgctga    240
 ggcccgggag caggaggcgg cccccggcgg agcgggtggc ctggcggccg gaaaggcgtc    300
 cggggcggac gagcgcgaca cgcgcaggaa ggccgggcct gcctggatgg tgcgccgcgc    360
 cgagggcctg gggcacgagc agacgccgct gcccgcggcc caggcccagg tccaggccac    420
 cggccccgag gctggcaggg ggcgcgccgc ggcggacgcc ctcaaccggc aaatccgcga    480
 ggaggtggcg agtgcagtga gcagctccta caggaatgaa ttcagggcat ggacggacat    540
 caagcctgtg aaaccaataa aggccaagcc ccagtacaag cccccagatg ataagatggt    600
 tcatgagacc agctacagtg ctcagttcaa aggagaggcc agcaagccaa caacagctga    660
 caataaggtc attgatcgca gaagaatacg cagcctctac agcgaaccct tcaaggaacc    720
 cccaaaggtg gaaaaaccta gtgttcagag ttccaaacca aaaaagacct cagcgagcca    780
 taagcccacg aggaaggcca aagacaagca ggcggtgtca ggccaggctg ccaagaaaaa    840
 gagcgcggag ggcccgagta ccaccaagcc agacgacaag gagcaaagca aagagatgaa    900
 caataaactg gctgaggcga aagagtaaat ttccctgcac tttcctttta ctcttctctc    960
 tctctccctc cccccaactt ttttttttta aaccaacaaa ccaaaaaagg ccacaaaatt   1020
 aattagaggc ttctcatctg ccttggtcct gagggttcca ggagctcttt ggtttggctt   1080
 cttttgatgg aagaatcctg cttcacagac tgagtggcag gcctcctcct gagggccagc   1140
 ccctgggagc accagggaag cgttgccgct ggctgtgccc tcccctgggc actctgactg   1200
 catgctgatg agcaaggcag gcaggtctga gaggcgaaac gaatctcccg gcagtgcttg   1260
 ggaagtgtct gtgggggtct cctcctccca gatccccaag atctgttgtc actggtcgat   1320
 tttgaacttt aggtacatgt gttcttttca aaaattcaga gaatcgtcat gttgccacag   1380
 aagctcagcc tgggcttcag caattgacaa aatttgaaga aatattaaac aaaaataaca   1440
 aaaaaagaaa caaccttggc cttaatgtca ataaaaggga gttgtgtctg ttaaaaaa     1498



      <210> 2350
      <211> 924
      <212> DNA
      <213> Homo sapiens


      <400> 2350
 tacaaaggca ttttatttta gtaaacaaaa tactggttat tattattttt tttaatttta     60
 attttacctt tttttttttg gagacgcagt cgctctgtca cccaggctgg agggcagtgg    120
 cacgacctag gctcactgca acctccacct cccggattca agcaattctc ctgcctcagc    180
 ctcccgagta gctgggatta cagacgcgcg ccactacacc tggctaattt ttatattttt    240
 agtagagaca ggattttacc atgttggcca ggctggtctc aaactcccga tctcaggcga    300
 tccactcgcc tcggcctccc aaagtgctgg gatttcaggt aaaagccagc atacccggcc    360
 agtactggtt cttttaaaaa catatacaaa ttcacactat tttaagtgaa aggtctaggt    420
 tgggagttta tcctctgaca aattattcaa taattaagtc tttcttctct ttcttctcag    480
 ctggagtcca ctcaagctga catttacatg gcagaatctt cagttatctt ttttctctga    540
 ttgcttcttc ctttcagcct ccagtttttg ttgttttgcc tccaaccttt ttctttgata    600
 cattttcacc ccagcaaatg tcaggcagag aattaatgtt tttgctgcca agatatacag    660
 cagcaggggc acgtgctcaa gaaccttcca attcatggta gactgtgaat tcactcctga    720
 tcaacacaag cccccaacag acaagtacat gagaggcagc tggaaggtct gatctgggca    780
 ggaagaaaga agcaggtcaa tttggagttc ctagggcaga ccaccttaga aagatgtctc    840
 tttgatggag agagggaatg tgaacagaaa gtgagctcca cagagaggtg ggctgtgtcc    900
 tgacaaggcg attgagctcg tgcc                                           924



      <210> 2351
      <211> 2544
      <212> DNA
      <213> Homo sapiens


      <400> 2351
 cccacgcgtc cgatgacatt ccaccacaaa agtgtaaatg gccggtcctt gccttgagtg     60
 atgacattac cttgtgaaag tccttttcct ggctcgtcct ggctcaaaaa gctcccccac    120
 tgagcacctt gcgaccccca ctcctgcccg ccagagaaca aacccccttt gactgtaatt    180
 ttcctttacc tacccaaatc ttataaaacg gccccacccc atctcccttt gctgactctc    240
 ttttcggact cagcccgcct gcacccaggt gaaataaaca gccatgttgc tcacacaaag    300
 cctgtttggt ggtctcttca cacggacgcg catgaaattt ggtgccgtca ctcggatcgg    360
 gggacctccc ttgggagatc aatcccctgt cctcctgctc tttgctccat gagaaagatc    420
 cacctacgac ctcaggtcct cagacagacc agcccaagaa acatctcacc aatttcaaat    480
 ccggtaagcg gcctcttttt actctcttct ccaacttgcc tcactatccc tcaacctctt    540
 tctcctttca atcttggcgc tacacttcaa tctctccctt ctcttaattt caattccttt    600
 cattttctgg tagagacaaa ggagacacgt tttatctgtg gacccaaaac tccggcgctg    660
 gtcacggact gggaaggcag ccttcccttg atgtttaatc attgcaggga cacctctctg    720
 attattcacc catgtttcca aggtgtcaga ccatgcaggg acgcctgcct tagtccttca    780
 cccttagcgg caagtcccgc ttttctgggg aaggggcaag tacccctcaa ccccttcttc    840
 acccttagtg gcaagtcccg cttttctggg ggaggagcaa gtaccccaac cccttctttc    900
 catgtctcta cgccttctct gcttttctgg ggaaggggca agtacccctc aaccccttct    960
 tcacccttag tggcaagtcc cgcttttctg gggaaggggc aagtacccct caaccccttc   1020
 tccttcaccc ttagcggcaa gtcccacttt cctgggacag gggcaagatt taattaacct   1080
 cgccttcaag gtgtacaata atagaaaaaa gttgcaattc cttgcctcca ctgtgagaca   1140
 aaccgcagcc acatctccag cacacaagaa cttccaaatg cctgaaccgc agcggccagg   1200
 cgttcctcca gaacctcctc ccacaggagc ttgctacatg tgccggaaaa tctggccact   1260
 gggccaagcg aattccgcag cccgggattc ctcctaagcc gcgtcccatc tgtgtgggac   1320
 cccactgaaa atcggactgt tcaactcacc tggcagccac tcccagagcc cctggaactc   1380
 tggcccaagg ctctctgact gactccttcc cagatcttct cggcttagcg gctgaagact   1440
 gacactgccc gatcgcctcg gaagccccct agaccatcac ggacgccgag cttcgagtaa   1500
 ctctcacagt ggaaggtaag ccctttccct tcttaatcaa tacggaggct actcactcca   1560
 cattaccttc ttttcaaggg cctgtttccc ttgcctccat aactgttgtg ggtattgacg   1620
 gtcaggcttc taaacctctt aaaactcccc aactctggtg ccaacttaga caatactctt   1680
 ttaagcactc ctttttagtt atccccacct gcccagttcc cgtattaggc tgagacactt   1740
 taactaaatt atctgcttcc ctgactattc ctggactaca gctatatctc attgccgccc   1800
 ttcttcccaa tccaaagcct cctttgcgtc ctcctcttgt atcccccgac cttaacccac   1860
 aagtataaga tacctctact ccctccttgg tgaccgatca tgcacccctt accatctcat   1920
 taaaacctaa tcacccttac cccactcaac gccaatatcc catcccgcag catgctttaa   1980
 aaagattaaa gcctgttatc actcgcctgc tacagcatgg ccttttaaag cctataaact   2040
 ctccttacaa ttcccccatt ttacctgtcc taaaaccaga caagccttac aagttagttc   2100
 aggatctgcg ccttatcaac caaattgttt tgcctataca ccccgtggtg ccaaacccat   2160
 atactctcct atcctcaata cctgcctcta caacccatta ttctgttctg gatctcaaac   2220
 atgctttctt tactattcct ttgcaccctt aatcccagcc tctcttcgct ttcacttgga   2280
 ctgaccctga cacccatcaa gctcagcaac ttacctgggc tgtattgctg caaggctgca   2340
 gggacagccc tcattacttc agtcaagccc tttctcatta tttactttct ttctgtccat   2400
 ctgcttctca ccttattcaa tattgtaacg accttctact ttgtagttcc ccctacaaat   2460
 cctcccaaca ggacaccctc ctgctcctcc aacatctatt ctcaaaggga tatctcgtat   2520
 ccccctccaa agcccaaatt tctt                                          2544



      <210> 2352
      <211> 813
      <212> DNA
      <213> Homo sapiens


      <400> 2352
 atggggtttc gccatgttgg ccaggctggt ctcgaactcc tgactttggg tccaacccaa     60
 aatgtccccc cattagagcc tctcctgggg cagaattaca agctctttcc tccactgtca    120
 cgacaccata ctggggaata cttgtcacag cagtgtttcc ccactgaggc ctcagaccga    180
 gacaatgtcg ccaagaccat cctgctgggc ggcagggccc tgggcctgga gaagtgcctg    240
 aaattcttgg acaatccgga tgcacagacc gaacttggtc aaaggcagga ggcaggaccc    300
 aggctcctgg gcccagatcc agagctggac gccgagtctc tgggcaggaa atcagggctc    360
 cagggcccct gggctgccgg catggaggct gggagctccc tggacaccgg aagcagcctc    420
 tccactgacc gctacagagc ccagctgccc ccaccccaag caccatgtgg ctacatgccc    480
 ctctccgtgt ctccgcggag acgttaccgt ggtccagctg gagaccaaaa ggtgaaaatg    540
 ctcaagttca aggccttttg cctggattac tggcagttcc tgtgcctaca gcccctgcat    600
 ggagcctaca aaagggattc ggatttgatg acatggattt ggggactgct ccctgaggtg    660
 acaggggctg caggcaccac aagcccgaat gttcatacct ccggcaggtt cttccgagcg    720
 tgtgtgttct gtccagtgca caccttggtc aagaaagaac cacatccggg ccagcaggag    780
 atcatcatgg agccgtcgcc atggtcacct tga                                 813



      <210> 2353
      <211> 476
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(476)
      <223> n = a,t,c or g


      <400> 2353
 ngtagttncc caggntgnnc caanccaggg anncctagnn agctnngcan nnnccacgaa     60
 cccgggaggc agaggttgca gtgagccgag accacgccac tgcactccag cctgggcgac    120
 agagcgagac tccgtctcaa aaaaacaaaa aaaaaagaga gatgcagggc ctgggtgtga    180
 tcgggcccct ggccccagcc cctggctcca gctgcctcct tgcaggaaac ccactggaca    240
 agggaggagg tgttgatctg tgaggggcag ccagcaacca ctctcactgt ggggaacttg    300
 gcaaaggaca gccccaggta ttcaccaaat caactgtaag gaaaagaaag ggatggcgtg    360
 gaagctgtag gggaaagaga tttaaaagac acatcagata aaaaagtggc tcaaactaag    420
 ctgtcatgtt taaagataga gatattaaat aatttgacct aaatgaaagt gtagaa        476



      <210> 2354
      <211> 4805
      <212> DNA
      <213> Homo sapiens


      <400> 2354
 gaaaaaggct tgaaaacata caaaaaaccc tagaggtggc tttctcagag gcagtgtgga     60
 tgcagccatc tgttgtcctg ctggatgacc ttgacctcat tgctggactg cctgctgtcc    120
 cggaacatga gcacagtcct gatgcggtgc agagccagcg gcttgctcat gctttgaatg    180
 atatgataaa agagtttatc tccatgggaa gtttggttgc actgattgcc acaagtcagt    240
 ctcagcaatc tctacatcct ttacttgttt ctgctcaagg agttcacata tttcagtgcg    300
 tccaacacat tcagcctcct aatcaggaac aaagatgtga aattctgtgt aatgtaataa    360
 aaaataaatt ggactgtgat ataaacaagt tcaccgatct tgacctgcag catgtagcta    420
 aagaaactgg cgggtttgtg gctagagatt ttacagtact tgtggatcga gccatacatt    480
 ctcgactctc tcgtcagagt atatccacca gagaaaaatt agttttaaca acattggact    540
 tccaaaaggc tctccgcgga tttcttcctg cgtctttgcg aagtgtcaac ctgcataaac    600
 ctagagacct gggttgggac aagattggtg ggttacatga agttaggcag atactcatgg    660
 atactatcca gttacctgcc aagtatccag aattatttgc aaacttgccc atacgacaaa    720
 gaacaggaat actgttgtat ggtccgcctg gaacaggaaa aaccttacta gctggggtaa    780
 ttgcacgaga gagtagaatg aattttataa gtgtcaaggg gccagagtta ctcagcaaat    840
 acattggagc aagtgaacaa gctgttcggg atatttttat tagagcacag gctgcaaagc    900
 cctgcattct tttctttgat gaatttgaat ccattgctcc tcggcggggt catgataata    960
 caggagttac agaccgagta gttaaccagt tgctgactca gttggatgga gtagaaggct   1020
 tacagggtgt ttatgtattg gctgctacta gtcgccctga cttgattgac cctgccctgc   1080
 ttaggcctgg tcgactagat aaatgtgtat actgtcctcc tcctgatcag gatggaagtt   1140
 ccagctctga tagtgaccta agtctgtctt caatggtctt tcttaaccat agcagtggct   1200
 ctgacgattc agctggagat ggagaatgtg gcttagatca gtcccttgtt tctttagaga   1260
 tgtccgagat ccttccagat gaatcaaaat tcaatatgta ccggctctac tttggaagct   1320
 cttatgaatc agaacttgga aatggaacct cttctgattt ggaggacgaa tccatgaacc   1380
 aaccaggacc aatcaaaacc agactggcta ttagtcagtc acatttaatg actgcacttg   1440
 gtcacacaag accatccatt agtgaagatg actggaagaa ttttgctgag ctatatgaaa   1500
 gctttcaaaa tccaaagagg agaaaaaatc aaagtggaac aatgtttcga cctggacaga   1560
 aattctttga tgaaatcact gagctgacat acctgccctc ttttcaccat aaagctgctc   1620
 ctcaccaggc cgagccaggt cccaattctt cctcagcctc tgctccccca ccctataatc   1680
 cttttatcac ctcctctcct cacactcagt ccggcttaca gtttcgttct gtgactagcc   1740
 ctcccccatc tgcccaacaa tttcctctta aagaggtggc tggagctaaa ggcatagtca   1800
 agacagcttt agagactgct cccacactag ctctccctgt ctcatcccaa cccttttcat   1860
 tacacacagc cgaagtgcag ggctgtgcag tcggaattct tacacaagga ccgggaccat   1920
 gccctgtagc ctttttgtcc aaacaacttg accttactgt tttaggctcg ccatcatgtc   1980
 tccatgcggt agcttccgct gccctaatac ttttagaggc cctcaaaatc acaaactatg   2040
 ctcaactcac tctctacagc tctcacaact tccaaaatct attttctttc tcacacctga   2100
 cgcatatact ttctgctccc cggctccttc agctgtattc actctttgtt gagtctccca   2160
 caattaccat tcttcctggc ccagacttca atctggcctc ccacattatt ctggatacca   2220
 cacctgaccc tgatgattgt atgtctctga tctacctgac attcacccca tttccccata   2280
 tttccttctt ttctgttcct catgttgatc acatttggtt tactgacggc agttccacca   2340
 ggcctgatcg ccactcacca gcaaaggcag gctatgctat agaatcttcc acatccatca   2400
 ttgaggctac tgctctgccc ccctccacta cctctcagca agccgaactg attgccttaa   2460
 ctcgggcctt cactcttgca aagggactac acgtcaatat ttatactgac tctaaatatg   2520
 ccttccatat cttgcaccac catgctgtta tatgggctga aagaggtttc ctcactacgc   2580
 aagggtcctc catcattaat gcctctttaa taaaaactct tctcaaggct gctttacttc   2640
 caaaggaagc tggagtcaca cactgcaagg gccaccaaaa ggcgtcagat cccattactc   2700
 taggaaatgc ttatgctgat aaggacagga cgatagatgg ttcctcccag gtgattgagg   2760
 aaaaaaacca caatgggtat tcagtaattg atacggggac tcttgtggaa gcagagttag   2820
 aaaaattgcc taataactgg tctcctcaaa cgtgtgagct gtttgcactc agccaagcct   2880
 taaagtactt acagaatcaa aagactatct caatcctgat tcaaaaggaa cccagcccag   2940
 ctctaggact cacccctgag cgcaaaggca atgttgggca tgctggtaaa ggaccactag   3000
 aatccagcag cccagacccc tttctttgtg gtcaagaaag gcgggaaaag gggtgcagga   3060
 ctgctacatc ggtaagcata actaatccga taaacagagg tccatgggtg gttacgcacc   3120
 ctggaaagga actcacccct gagcacaaag gcaatgttgg gcacgctggg agagacattc   3180
 tagcaaaagc aggggccatt atacacctga acataggaga aggaacaccc gtttgttgtc   3240
 ccctgcttga ggaaggaatt aatcctgaag tctgggcaac agaaggacaa tatggacgag   3300
 caaagaatgc ccgtcctgtt caagttaaac taaaggattc cacctccttt ccctaccaaa   3360
 ggcagtaccc cctcagaccc aaggcccaac aaggactcca aaagattgtt aaggacctaa   3420
 aagcccaagg cctagtaaaa ccatgcagta acccctgcag tactccaatt ttaggagtac   3480
 agaaacccaa cagacagtgg agaaaccttg tgccatcaag ccacccaagc gctcttcaat   3540
 ttcctcgcta cctgtggcta catggtttcc aaaccaaagg ctcaactctg ctcacagcag   3600
 gttacttagg gctaaaatta tccaaaggca ccagggccct cagtgaggaa cacatccagc   3660
 ctatactggc ttatcctcat cccaaaaccc taaagcaact aaggggattc cttggcgtaa   3720
 taggtttctg ccgaaaatgg attcccaggt atggcgaaat agccaggtca ttaaatacac   3780
 taattaagga aactcagaaa gccaataccc atttagtaag atggacaact gaagtagaag   3840
 tggctttcca ggccctaacc caagccccag tgttaagttt gccaacaggg caagactttt   3900
 cttcatatgt cacagaaaaa acaggaatag ctctaggagt ccttacacag atccgaggga   3960
 tgagcttgca acctgtggca tacctgacta aggaaattga tgtagtggca aaggtggtgg   4020
 cagtagcagt cttagtatct gaagcagtta aaataataca gggaagagat cttactgtgt   4080
 ggacatctca tgatgtgaat ggcatactca ctgctaaagg agacttgtgg ctgtcagaca   4140
 actgtttact taaatgtcag gctctattac ttgaagggcc agtgctgcga ctgtgcactt   4200
 gtgcaactct taacccagcc acatttcttc cagacaatga agaaaagata aaacataact   4260
 gtcaacaagt aatttctcaa acctatgcca ctcgagggga ccttttagag gttcctttga   4320
 ctgatcccga cctcaacttg tatactgatg gaagttcctt tgtagaaaaa ggacttcgaa   4380
 aagtggggta tgcagtggtc agtgataatg gaatacttga aagtaatccc ctcactccag   4440
 gaactagtgc tcagctagca gaactaatag ccctcacttg ggcactagaa ttaggagaag   4500
 aaaaaagggc aaatatatat acagactcta aatatgctta cctagtcctc catgcccatg   4560
 cagcaatatg gaaagaaagg gaattcctaa cttctgagag aacacctatc aaacatcagg   4620
 aagccattag gaaattatta ttggctgtac agaaacctaa agaggtggca gtcttacact   4680
 gccggggtca tcagaaagga aaggaaaggg aaatagaaga gaactgccaa gcagatattg   4740
 aagccaaaag agctgcaagg caggaccctc cattagaaat gcttataaaa caacccctag   4800
 tatag                                                               4805



      <210> 2355
      <211> 594
      <212> DNA
      <213> Homo sapiens


      <400> 2355
 atgacaccaa gaggcacagg tggagatagt gaagttcctt tccaagcagc aaaacctctt     60
 tctgtgaaac agggggttag ctttcggctt tgggctcgga ggaggccaag gtgcgacttt    120
 cttcggtcgt cccgaatccg ggttcatccg acaccagccg cctccaccat gccgccgaag    180
 ttcgacccca acgagatcaa agtcgtatac ctgaggtgca ccggaggtga agtcggtgcc    240
 acttctgccc tggcccccaa gatcggcccc ctgtgtctgt ctccaaaaaa gaacagacag    300
 gcccagattg aggtggtgcc ttctgcctct gccctgatca tcaaagccct caaggaacca    360
 ccaagagaca gaaagaaaca gaaaaacatt aaacacagtg ggaatatcac ttttgatgag    420
 atcgtcaaca ttgctcgaca gatgcggcac cgatccttag ccagagaact ctctggaacc    480
 attaaagaga tcctggggac tgcccagtct gtgggctgta atgttgatgg ccgccaccct    540
 catgacatca tagatgacat caacagtggt gctgtggaat gcccagccag ttaa          594



      <210> 2356
      <211> 1092
      <212> DNA
      <213> Homo sapiens


      <400> 2356
 tttttttttt ttaagaattt gtaccagtaa atttattcca agtaagactt gtgtgcacac     60
 accaggcaga taatttccac acaaacacca aacattgtag taaaactagt taacactttg    120
 gccatgaaac tcaaagatac ttgaaaaacc tctcgatagc actttgagtc acttaattct    180
 gacaaatatt aatatgtcat ccatgcttgc ccagttataa ttttacaata taattgtatt    240
 tttcattgta cttattattc attatactta ctatatatat ttaaaacatc tttgctgaaa    300
 ttctcttatc ccaaaaataa tttttcagta actccaaaat acccacatgt acctcttagc    360
 aggctattcc aatatcaaaa ttctttttct tcaagtaaca agttctcaat ccacaccatt    420
 cctgatcaca gatataactg atatgcagtt ttataaacag ctcttttact ccttgttcct    480
 attttagcag gccaaccatc acttcactga tatcccagag ttttcttgca acagattcat    540
 ccatagcttt gggcaacagt tcttcctctt tacaatcccc aaagtatctt cctgacactc    600
 cttctacctc aggtgaagag gccaaataaa tggaagtctg ggcaccttct actggagttt    660
 tgaaaaaagc ccatgacacc aaattgaaga gtggtttgac caacagtgga atgtgtatgt    720
 gcctccccag atttgtccgt acaataccag gatgcaacac attgacggtg acatttgtgc    780
 cttctaagcg gcgggctagt tccctggtaa aaagaatgtt agccagtttg ctccggctat    840
 aacaaaagct tttattatag ctttgttcac tgttcaagtc atcaaaattg atgtctccgt    900
 atttataaag tttggaagaa actaccacaa tcctgctggg agctgaactt ttgaggagtc    960
 caaggagaag attggtgagt agaaagtgcc ccagatggtt cactccgaac tgcatctcaa   1020
 acccatcttc agtcttcatg taagggcact ggaagatccc tgcgttattg atcaagacat   1080
 cacagcctat gc                                                       1092



      <210> 2357
      <211> 8160
      <212> DNA
      <213> Homo sapiens


      <400> 2357
 atgactaaac actatgatta catcgccatc ggcggcggca gcggcggtat cgcctccatc     60
 aaccgcgcgg ctatgtacgg ccagaaatgt gcgctgattg aagccaaaga gctgggcggc    120
 acctgcgtaa atgttggctg tgtgccgaaa aaagtgatgt ggcacgcggc gcaaatccgt    180
 gaagcgatcc atatgtacgg cccggattat ggttttgata ccactatcaa taaattcaac    240
 tgggaaacgt tgatcgccag ccgtaccgcc tatatcgacc gtattcatac ttcctatgaa    300
 aacgtgctcg gtaaaaataa cgttgatgta atcaaaggct ttgcccgctt cgttgatgcc    360
 aaaacgctgg aggtaaacgg cgaaaccatc acggccgatc atattctgat cgccacaggc    420
 ggtcgtccga gccacccgga tattccgggc gtggaatacg gtattgattc tgatggcttc    480
 ttcgcccttc ctgctttgcc agagcgcgtg gcggttgttg gcgcgggtta catcgccgtt    540
 gagctggcgg gcgtgattaa cggcctcggc gcgaaaacgc atctgtttgt gcgtaaacat    600
 gcgccgctgc gcagcttcga cccgatgatt tccgaaaacc agagccggag cggcgctgtt    660
 cgtgatgaga ttcagttcta cgccacaggt gcgcgtccgg atctggcaaa agagatgggc    720
 tttatcggtg gcaaaatgcc gacgcactgg gggccacatg atggcgatgc ggggatccgc    780
 aaagatgccg ctatggtcgc ggatatgcgt gtaaaatgcg cggaacgttg cgaccgcatc    840
 tcactgatgc acgccggaaa agtgcttgcc agcggtacac cgcaggaact ggttgagaaa    900
 cgcggagccg ccagtctgga agaggcattt atcgcctatt tgcaggaagc ggcagggcag    960
 agcaacgaag ccgaagcgcc gcaccgtgct acagccgccg cgaagcgctg gaactgcgac   1020
 gcgatccagt acgttcggac gctggcgctg atgggaacgg tgatcctgat gctgataatg   1080
 ggttacggca tcagtatgat gtggaaaacc tgcgctttaa agtgctggag ggatttttgt   1140
 ggatcggact tcagattgat aaaggggacg ccgcgtagct ccgacgacag cataaaaatc   1200
 ttgccgccaa ttttaaaaac atcgaactcc gggccaaaag gccagcaaag ctcgacaaag   1260
 ggtaactcaa gcatggcaac tgactcaaca caatgtgtaa aaaaaagccg tggccgccca   1320
 aaagtgttcg acagggatgc cgcgcttgat aaggccatga aattgttctg gcaacacggt   1380
 tatgaagcga cttctcttgc ggacctcgtc gaagcgaccg gagccaaagc gcccacgcta   1440
 tacgcggaat ttaccaacaa agaggggtta tttcgtgccg ttctcgaccg ctatatcgat   1500
 cgttttgccg ctaagcatga agcacagctg ttttgtgaag agaaaagcgt ggagtctgcg   1560
 ctggctgact attttgctgc catcgccaac tgctttacca gcaaagacac cccggcaggc   1620
 tgcttcatga tcaacaactg caccaccctc tccccagatt caggagatat cgccaatacg   1680
 ttgaaatcac gccatgcgat gcaagagcgc actttgcagc agtttttatg tcaacgacaa   1740
 gcgcgcgggg aaatcccgcc ccactgtgac gtgacacatc tggcagaatt ccttaattgt   1800
 attattcagg ggatgtcgat cagcgcacgc gaaggtgcat cgctggaaaa actgattgcc   1860
 cctgaacctc gcacccctcc tgcctcgttc aggaagctcc gcacctatcc ggccgccacc   1920
 ctcagcacag gcacggcagc cgatgaaatc tacgtatggc gtggacagac gccattcgtg   1980
 atgtcgatag ctgccacaag gcaacggtct tctcacccga cctggttcaa cggtaatacg   2040
 caacacgcgc ccaacttctg ccgctttgct cggtttgcct tcagcgtcga acgcctgggc   2100
 aatcgccggg ccgcgttttt cgatttcacg atccggttgc gcttccgcca gaatggggtc   2160
 ccaaacgaga gattcgacgt aaacgtccgc tcccaactaa gttctcaggc gctgacaacg   2220
 acaagaattc ctcacacaat acgtagcgct tcaatcacta aaccgctttc acagccctcg   2280
 acctgccgcg atatgtccgc cgcccaccgt caggccattg ccgacattac gccgaaatat   2340
 atggaagatc tggatcaacg ctggatggac tatggcgtta agttcctcga caagatggcg   2400
 aagagcgata aaccattctt cctctactac ggcactcaat tcgccacttt cgctccagga   2460
 tgccctgcca gatccagcgc gtggaggcta acctccacga tttcaattag cggtatggag   2520
 cttcccatgg ccccggcttt tcccattccg aggcaaaacc cttggtcgat ggccccagct   2580
 tgccttttga ctggcacttc gggccacaac ggcggcagtg gcgcgaaggg cgaggacagg   2640
 ggggtctttg gggggcggcc tcctatcacg gagtttccct tcggttccac ttggaacttc   2700
 cgcgtgtgcg gcttacggag tccggtaacc gcgctatgcc gaggcgaagg cgggcaaccc   2760
 cagggcgcgc aggtccaaca gcggccgggt aaaatcaccg gggaaaattt ccgacaagga   2820
 aactccaggg gggggcatca aaacgcccag ggacacggac accccctggt acaacgccac   2880
 acagggggcc ccaggcacaa gaagggggcc acagaacacc ccgggtacac cagcgcaccc   2940
 gcaaatccat ccgcagagct gaaaatctac gatacctcat cacaaccact tagccagatc   3000
 ttaagccagg ttcagcagga tggcgcgagt attgtggtcg gtccgttgct gaaaaataac   3060
 gttgaagagt tgctgaagct ttcaaaagcc ctctacaaca ttgactggca tcgccacgcg   3120
 caggtgaagt gcaacggctt gcagatcaat atgttgatgg ctgccgccgt ctgcgccgtc   3180
 attgccagca acctcggcat gttcgtggta atggccgaaa tcatggccct gtgcgcgcaa   3240
 cagcaaagag ggcaactgtg gtttgcgctg gggcgtcttg gcactctgct gctggcgatt   3300
 gcttgctggc tgctgtggca gcgttacggc acgctggatc tgcgcctgct ggatatgcgt   3360
 atgcaacagc tgccgctcgg ttccgatatc tggctgctcg gagtgattgg ctttggcctg   3420
 ctggccggga ttattccgct gcacggctgg gtgccgcagg cacatgcgaa cgcctctgcg   3480
 ccagctgccg cgttgttttc tacggttcat gtgtacaaac gcgtaattct gaccggtgac   3540
 catatcaccg actccacttc cagccaggac gaatacaacc aaccgcaggt taacatctcg   3600
 ctcgatagcg ctggtggtaa catcatgtct aacttcacta aggacaacat cggcaaaccg   3660
 atggcaaccc tgtttgtgga gtacaaagac agcggtaaga aagatgcaaa tggtcgtgcg   3720
 gttctggtga aacaggaaga ggtgattaac atcgccaaca tccagtctcg tctgggtaac   3780
 agcttccgta tcaccggcat caacaacccg aacgaagccc gtcagctgtc actgctgctg   3840
 cgtgccggtg cgttgatcgc gccgattcag attgttgaag aacgtaccat tggcccaacc   3900
 ctgggtatgc agaacatccg atggggctac ggccgttccc agcctgcgga gctgacaaaa   3960
 ctgtcgctgt tttgctatat cgccaactat ctggtgcgta aaggcgacga agtacgtaat   4020
 aacctgcgcg gcttcctgaa accgatgggc gtgattctgg tgttggcagt gttactgctg   4080
 gcacagccag accttggtac ggtggtggtg ttgtttgtga ctacgctggc gatgttgttc   4140
 ctggcgggag cgaaattgtg gcagttcatt gccattatcg gtatgggcat ttcagcggtt   4200
 gtgttgctga tactcgccga accgtaccgt atccgccgtg ttaccgcatt ctggaacccg   4260
 tgggaagatc cctttggcag cggctatcag ttaacgcaat cgctgatggc gtttggtcgc   4320
 ggcgaacttt gggggcaagg tttaggtaac tcggtacaaa aactggagta tctgccggaa   4380
 gcgcacactg actttatttt cgccattatc ggcgaagaac tggggtatgt cggtgtggtg   4440
 ctggcacttt taatggtatt cttcgtcgct tttcgcgcga tgtcgattgg ccgtaaagca   4500
 ttagaaattg accaccgttt ttccggtttt ctcgcctgtt ctattggcat ctggtttagc   4560
 ttccaggcgc tggttaacgt tcgcgcgggg gccggggatg taccgaccaa gtacaactca   4620
 ctgagttgct tcaaagaaac gcgaaatgcg atattgggcc gcctgatgac gcctgctcat   4680
 gggcatgtct ggctggatgg cgagcacatt caacattacg ccagtaaaga ggttgcacgc   4740
 cggattggtc tgttggcgca aaatgctacc acgccgggcg atatcaccgt gcaggagctg   4800
 gtggcgcgtg gacgttatcc gcatcaaccg ctgtttaccc gctggcgcaa agaggatgaa   4860
 gaagcggtaa cgaaagcaat gcaggccacg ggaataactc atctggcaga tcaaagcgtg   4920
 ataccctttc ggtccaggct agttaaaaac agaaaggcag cctggcatag tggtagcaga   4980
 gacacagcag caactctcat gctgtttgtg ctggggtggc tgggccgacg gaggggtcta   5040
 ggctgttgtg ggatctgggg tggtttcagt caacaaggtc tcccgcctgc catgcagaaa   5100
 gtcatgtata agggactcgt ccccgaggat aaaacattga gagaaataaa agtgaccagt   5160
 ggggccaaga tcatggtggt tggctccacc atcaatgatg ttttagcagt aaacacaccc   5220
 aaagatgctg cgcagcagga tgcaaaggcc gaagagaaca agaaggagcc tctctgcagg   5280
 cagaaactac attgttgctt attcacttta gtggcaagta ttattgtgcc agctgctttt   5340
 gttttggaag atgtggactt cgaccaaatg gtttcactgg aagcaaatcg tagttcttac   5400
 aatgcatcct ttccctcaag ctttgaactc tcagcaagtt cccactcgga tgatgatgtc   5460
 atcatagcca aagagggaac tagcgtttca attgagtgtc ttctcacagc cagtcactat   5520
 gaagatgtcc attggcacaa ttcaaaagga cagcaactgg atggcagaag cagagtaatt   5580
 gctctagtcc cagttactcc agcgatccag cccaatgcgc gtatacggcg tcaccgagtg   5640
 gttgccgagc gtcagcggca aataggcgcg aatttcttgc gtggaaaact caccgttatt   5700
 gcggctgtcg tccatattga agccgcgctc gagataatag ttcactcgca aggcaaccgt   5760
 ttcgttgaag gacagtacca agctgtccag cacgctgtcg tgcggatacc ggtagggcca   5820
 ggccgtggct ccggtgcggg ttcactggtg gcctacgcgc tgaaaatcac cgacctcgat   5880
 ccgctggaat ttgaccgtgc tactgtaagg gttctgaatg gtgacaatac gcggcagatc   5940
 gtgtttgtcc gccagatgca ggtagcgcat tacgccaaat gcagtttcgt tcgacacgcc   6000
 gatataacga atttttcccg cgcgttggta ctctgccagt gcgtccagcg tatccagcag   6060
 cgaaaccgca ggcgcagaat ccgtccagct ataaccgagt ttgccgaagc agttggtcgg   6120
 gcgctgcggc cagtgcacct gataaagatc gaggttaatg ccctgagcga cggcatagtc   6180
 gagttgtgcg tgggcgtcgg cttcgctgtt ctgttcattc tcagcgggaa atcggccaaa   6240
 catcggtacc acagaaaact gggaataaac agggtaaacg ccaattgtcc cggtttttac   6300
 gtcaatcgca tcttagcgcc ttacattaat gaagctatcc gcatgttgac ccaaggtgaa   6360
 cgggtagagc acattgatgc cgcgctagtg aaatttggtt ttccggtagg cccaatccaa   6420
 cttttggatg aggtaggaat cgacaccggg actaaaatta ttcctgtact ggaagccgct   6480
 tatggagaac gttttagcgc gcctgcaaat gttgtttctt caattttgaa cgacgatcgc   6540
 aaaggcagaa aaaatggccg gggtttctat ctttatggtc agaaagggcg taaaagcaaa   6600
 aaacaggtcg atcccgccat ttacccgctg attggcacac aagggcaggg gcgaatctcc   6660
 gcaccgcagg ttgctgaacg gtgtgtgatg ttgatgctga atgaagcagt acgttgtgtt   6720
 gatgagcagg ttatccgtag cgtgcgtgac ggggatattg gcgcggtatt tggcattggt   6780
 tttccgccat ttctcggtgg accgttccgc tatatcgatt ctctcggcgc gggcgaagtg   6840
 gttgcaataa tgcaacgact tgccacgcag tatggttccc gttttacccc ttgcgagcgt   6900
 ttggtcgaga tgggcgcgcc cctcgatgcc gccagtgatt ccgttcgtcc tctgaccact   6960
 aatggttgtg acgaatctcg cctgatggcg aactggctga aaggtcaaaa agtggaaatc   7020
 gaacgcgttc tggtgagccc gttcctgcga gccgagcaaa cactggaaga agtaggggat   7080
 tgtctgaacc tgccttccag tgcagaagtt ctgccggagt taacgccctg cggcgatgtt   7140
 ggtctgatgt ggattggcga taaaaaacaa ctgctgacgc cgctgcgcga tcagttcacc   7200
 cgtgcaccgc tggataacga cattggcgta agtgaagcga cccgcattga ccctaacgcc   7260
 tgggtcgaac gctggaaggc ggcgggccat taccaggccg aagcagcgtt gttgcagtgc   7320
 acggcagata cacttgctga tgcggtgctg attacgaccg ctcacgcgtg gcagcatcag   7380
 gggaaaacct tatttatcag ccggaaaacc taccggattg atgcgctggc ggtaattatg   7440
 ttctccttcg gcggtctgga gctgattggg attactgccg ctgaagcgcg cgatccggaa   7500
 aaaagcattc caaaagcggt aaatcaggtg gtgtatcgca tcctgctgtt ttacatcggt   7560
 tcactggtgg ttttactggc gctctatccg tgggtggaag tgaaatccaa cagtagcccg   7620
 tttgtgatga ttttccataa tctcgacagc aacgtggtag cttctgcgct gaacttcgtc   7680
 attctggtag catcgctgtc agtgtataac agcggggttt actctaacag ccgcatgctg   7740
 tttggccttt ctgtgcaggg taatgcgccg aagtttttga ctcgcgtcag ccgtcgcggt   7800
 gtgccgatta actcgctgat gctttccgga gcgatcactt cgctggtggt gttaatcaac   7860
 tatctgctgc cgcaaaaagc gtttggtctg ctgatggcgc tggtggtagc aacgctgctg   7920
 ttgaactgga ttatgatctg tctggcgcat ctgcgttttc gtgcagcgat gcgacgtcag   7980
 gggcgtgaaa cacagtttaa ggcgctgctc tatccgttcg gcaactatct ctgcattgcc   8040
 ttcctcggca tgattttgct gctgatgtgc acgatggatg atatgcgctt gtcagcgatc   8100
 ctgctgccgg tgtggattgt attcctgttt atggcattta aaacgctgcg tcggaaataa   8160



      <210> 2358
      <211> 484
      <212> DNA
      <213> Homo sapiens


      <400> 2358
 gaaactacag ctactgaaca tactccacca gagtgaaaga gaacacttct tcattcacag     60
 ggcaagaaac aaattagttt agggaataca gtatattgga catccaaagt ttcaacagtg    120
 acatgggaag ttcccaggaa aggaagtgct gagatgagca gagcagacac catactctct    180
 tcctctcctc cctccagact ccccgcaaca gcgggctgta cctgccactg gcaagtgcca    240
 cattttaaca acgatgatga taacagcaac atttcatctt caccacaacc ctatatggta    300
 tgtacgttat catcccaatt ttacagatat gaagaactga gggacgtaga gttcgagaaa    360
 cttgcttaaa attacacact actggcagaa ctaggattca aaccagcgtg tctggcccaa    420
 ggcactgcct tcttcacctg actatgccac cttgtctccc catactcgtt aactcacttg    480
 cctt                                                                 484



      <210> 2359
      <211> 413
      <212> DNA
      <213> Homo sapiens


      <400> 2359
 actttggttt caatgggtgt tccaaaagga tcatcaagct tcaggagctt tctgaccttg     60
 aagaaaggga aaatgaagat agcatggtgc cacttccgaa gcaaagcctg aagttcttct    120
 gtgctttaga agtggtgttg ccatcctgtg attgcaggag tcctggcatt ggcttggtgg    180
 aggagcctat ggataaggtg gaggaaggac cattatcatt ccttatgaaa aggaagacag    240
 cccagaagct tgctattcag aaggctttgt cagatgcatt ccagaaactg ttgattgttg    300
 ttctaggtaa gactgtcttg atcatccttg aagtacttca gtttcagtaa gcaaataaac    360
 tcattttgaa aagttaattg aataaaaata ttgatatcta aagcaaaaaa aaa           413



      <210> 2360
      <211> 3009
      <212> DNA
      <213> Homo sapiens


      <400> 2360
 cagtccggcc gggcggagct aggggcgggc ccctgcgtct ctgggcgctg gagcgcggcg     60
 actatcacgc cgcgtggcgg acggacggac tgacggacgc gcagccttac ccgaaaggcc    120
 atggcggagc acgcccctcg ccgctgctgc ctgggctggg acttcagcac gcagcaggta    180
 aaggttgttg ctgttgatgc agagttgaat gtcttctatg aggaaagtgt gcattttgac    240
 agagatcttc cagaatttgg gcatgtactt gatgtgcatg gtgttcatgt gcacaaggat    300
 gggctgacgg tcacttctcc agtactaatg tgggtccagg cactggatat catcttggag    360
 aagatgaagg cttcgggctt cgaattctct caagtcctag ccttgtccgg ggcgggccag    420
 caacacggaa gtatatactg gaaggctgga gcccagcagg cactgacaag cttatcacca    480
 gacctccggc tacaccagca gcttcaggac tgtttctcca tcagcgactg cccggtgtgg    540
 atggactcca gcaccacagc ccagtgccgc cagctggagg ctgctgtggg tggtgctcag    600
 gctctcagct gcctcacggg gtcccgtgcc tatgagttca acctggtttg tgatcggaag    660
 cacctgaagg acaccacaca gtcagtgttc atggctgggc tccttgttgg caccctcatg    720
 tttgggcccc tctgcgaccg gattggccgc aaggccacaa tcctggcgca gctgctcctc    780
 ttcaccctca tcggcctggc cacagctttt gtgcccagct ttgagctcta catggccctg    840
 cgctttgctg tggctactgc cgtcgctgga cttagcttca gcaatgtcac cctactgaca    900
 gaatgggtgg ggccctcatg gaggacgcag gccgtggtcc tggcccagtg caacttctcc    960
 ctcgggcaga tggtgcttgc gggactcgcc tacggtttcc gcaactggag gctccttcag   1020
 atcaccggca ctgcgcctgg cttactgctc ttcttctact tctgggctct gccagaatct   1080
 gcacgttggc tcctgacccg tgggaggatg gacgaggcga tacaactgat ccagaaaacg   1140
 gcctcggtca ataggcggaa actctccccg gagctcatga accagctggt cccagagaag   1200
 acaggcccct cagggaatgc cctggatctg ttcagacacc cccagctccg gaaggtgacc   1260
 ctgattatct tctgtgtctg gtttgtggac agtctggggt actacggcct gagcctccaa   1320
 gtgggggact tcggcctgga cgtctatctg acgcagctca tctttggagc tgttgaggtg   1380
 cctgcccgct gttccagcat cttcatgatg cagaggtttg gccgcaagtg gagccagttg   1440
 gggaccttgg tcttgggtgg cctgatgtgt atcatcatca tcttcatccc agcagatctg   1500
 cccgtggtgg tcaccatgct ggctgtggtg gggaaaatgg ccacagctgc tgcctttacc   1560
 atctcctatg tgtactctgc cgagcttttc cccaccatcc tccggcagac aggcatgggg   1620
 ctggtgggca tcttctcacg gatcgggggc atcctcacac cacttgtgat cctgctggga   1680
 gagtaccacg ctgccctccc catgctcatc tacggcagcc tccccatcgt ggccggcctg   1740
 ctgtgcaccc tgctgccaga gacgcatggc cagggcctga aagacaccct ccaggacctg   1800
 gagctggggc ctcacccacg gtcccccaaa tcagtgccct cagagaagga aacagaggcc   1860
 aagggaagaa cttccagccc gggagtggcc tttgtcagcc tgggcaccag tgacaccctg   1920
 tttctctggc tccaagagcc catgcctgcc ctggaaggcc acatcttctg caacccggtt   1980
 gactcccagc actacatggc actcctgtgc tttaaaaatg gctccctcat gagagagaag   2040
 atccgcaacg agtctgtatc ccgttcctgg agcgatttct ctaaggcact gcagtccaca   2100
 gagatgggca acggtggaaa cctgggtttt tattttgatg taatggagat cacccctgaa   2160
 attattggac gtcataggtt taacacagaa aaccacaagt actttaaagg aaaaggtgcc   2220
 cccggtcacc ccatgccctc tttgaaggca aattttgatt tgcttgcctg tctgcggggc   2280
 gttggcagca gcacactgct cctctggcca gcagtcctgg gtgcacagac caggcaagct   2340
 ggtgtcaacg aagggcggtc acaggtagct gacttccttc ggatccccgt cactgggtgc   2400
 ccagaacagc gcaggaaccc gccgagtcct ccggcccctc tgggcaccgg gggtcctgcc   2460
 gaggagcgcc tgcagtttcc tggggtagct gggtccaggc ggggtcgagg ccgcatcttg   2520
 cgagcgggtg gcattggcag ggcatctccg ggcgagggca ccggcgcccc acggccgcgc   2580
 gcagggcagg ggcgcggggg ccccgggaag cccgagagcg gaggaggcgg ccccgtggcc   2640
 ctgcggccag gcgactgtac ctgctgcgtg ctgaagtccc agcccaggca gcagcggcga   2700
 ggggcgtgct ccgccatggc ctttcgggta aggctgcgcg tccgtcagtc cgtccgtccg   2760
 ccacgcggcg tgatagtcgc cgcgctccag cgcccagaga cgcaggggcc cgcccctagc   2820
 tccgcccggc cggactgtgg accggagtca cgaggcgggc ttgcgctctg gcgccgcctg   2880
 cggggctacg cgagccggga ccgcgtcctg tgcaatcgac ggtgccccca cgcagcccgc   2940
 tttccttcga agcgcacccc ctctggttct ccccatcttc atcttatgtc ttcatgggcc   3000
 gtgccctga                                                           3009



      <210> 2361
      <211> 900
      <212> DNA
      <213> Homo sapiens


      <400> 2361
 atgacatatg gtgtgggcaa aggagatatg gtagatggaa cgaaggaaag aggtgagaga     60
 attgagtctg cattgggcac ctcacacatc atgagagtgg cagagccaca gggaagtcaa    120
 agctggtgcc ccgatgaaga actgaggcca gtgggctccc cagccaccgc cgctcagaag    180
 ctgccaagca cccccggtgc tttgggcccc acgcacagca ctgagtgctg cagtatcccc    240
 ttagacccca aggcccaaca aggactccaa aagattgtta aggacctaaa agcccaaggc    300
 ctagtaaaac cgtgcaatag cccctgcaat actccaattt taggagtaca gaaacccaac    360
 ggacagtgga ggttagtgca agatctcagg attatcaatg aggcccttgt ccctctatac    420
 ccagctgtac ctaaccctta cactctgctt tctcaaatac cagaggaagc agagtggttt    480
 acagtcctgg gccttaagga tgactttttc tgcatccctg tacatcctga ctctcaattc    540
 ttgtttgcct ttgaagaacc ttcaaacccc acatctcaac tcacctggac tgttttaccg    600
 aaagggttca gggatagccc ccatctattt ggccaggtat tagcccaaaa cttgagccaa    660
 ttctcatacc tggacactct tgtccttcgg tacgtggatg atttactttt agctgcccgt    720
 tcagaaacct tgtgccatca agccacccaa gcactcttaa atttcctcac tacctgtggc    780
 tacaaggttt ccaaaccaaa ggctcagctc tgctcacagg aggttacgta cttagggcta    840
 aaattatcca aaggcaccag ggccctcagt gaggaacgta tccagcctat actggcttaa    900



      <210> 2362
      <211> 2187
      <212> DNA
      <213> Homo sapiens


      <400> 2362
 ctttaagttg aagaagtgga gcatctttcc ttgaagaagt acattattga cattgtggtt     60
 gaaagtacag ctccagcaga agctttgaaa gatggagaag agcggcaaaa aaataaaaaa    120
 aaagccaaaa agataaaagc ccggatgaac ttcagggcta aggaatatga gagtttaatg    180
 gaaaccaaaa attctggctc tgattcacct tataaagcaa agcttcagcg attagccaaa    240
 gatcttctaa aacaagtaca agttcaagac agtggctcat gggcaaacaa taaagtgtct    300
 gctttggatc ggaccctagg agagatcact agaatactgg aaaaagagaa tgtggcagat    360
 cagattgcat ttcaagctgc tggtggatta acagcccttg aacacatcct tcaagcagta    420
 gtcccagcca caaatgtgaa cacagtttta aggaattcct cctaagtctc tctggcaatg    480
 caattcaatg tttacaacct tcacctggca attaactgtt tcaggaaaac ttgcagtgat    540
 gttctgttta gtaacaaggt ttaccttctt aatggggcct cctgatacac cagttgacgg    600
 tttatgttcc agatgaaaat aatactattt gggggagaaa tacaaataaa caagttttga    660
 aaggcttgac aactgggact tctcaaagtc agtgctgtgg gttttggggc tgcctggatt    720
 gccaatcgac caggtgggga aactgccagc caggctaccc caaaaatacc aacacaggaa    780
 atgaaaaaca aaccctcaca aggtgatcct tttaacaatc gagttcagga ccttatcagc    840
 tacgtggtga acatgggtct gattgacaaa ctgtgtgcct gcttcctctc ggtgcaaggc    900
 ccagtgggat gaggaatccc aagatgggcc atatttctgg caggcatgcc gcaggactct    960
 tacatgcaat gtgttacact gtgctttgct gtcactggaa ggtcatacag catatttgac   1020
 aataatcgcc aggatcccac agggctgaca gctgctcttc aggcaaccga cctggctgga   1080
 gttcttcata tgctctactg tgtcctcttc catggcacca tcttggaccc cagcactgcc   1140
 agtcccaagg agaattacac tcaaaatacc atccaagtgg ccattcagag tttacgtttc   1200
 ttcaacagct ttgcagctct tcatctgcct gcttttcagt ctattgtagg ggcagagggc   1260
 ttgtcccttg cattccggca catggccagc tccctgctgg gccactgcag ccaagtctcc   1320
 tgtgaaagcc tccttcatga ggtcatcgtc tgtgtgggct acttcactgt caaccaccca   1380
 gataaccagg gtgatcgtgc agtccggccg ccaccccaca gtgctgcaaa aagctctgcc   1440
 agttgccctt ccagtatttc agtgacccac ggctgatcaa agtactgttc ccctcacttt   1500
 atcgcagctt gttacaacaa ccatcagaac aagatcattc tggagcaaga gatgagctgt   1560
 gttttactgg cccctttcat tcaggatttg gcacagactc caggtcaagc ggaaaaccag   1620
 ccttaccaac ccaaagggaa atgccttggt ttcccaagac tatcttgagc tggctaacag   1680
 attttcctca ggcagggcct ggggaaagaa gctcgacagt ttttcttgaa aaaagagaaa   1740
 aaataaatgt tttggttgat tctgtatttg agtacccttg ttaatatttt aaattgtcca   1800
 aacaaacatt ctaattgttc cttaagaact cattttccca tgtttatact cttcccacac   1860
 tggtagatat ggcatgtact ttacactatt tataatgact gtagatactt gaatgttcta   1920
 cttgctaatt ttgcaagttg agtttatttc atttatgcag agtatcttgg agtttggtaa   1980
 tttccatctt atgataatat atactttgca tttgtgatat gggtgaaagg agacataaaa   2040
 ttagcaagtc tgttttgttc ttgtaataaa gtaacttatt ctgttttcat tgttgacttt   2100
 tcatgttaag gaaatacgaa tctgaaagaa aaatgttaac tccagctctt gaagtatctt   2160
 aaataaagac ttaattaaag tttaaaa                                       2187



      <210> 2363
      <211> 473
      <212> DNA
      <213> Homo sapiens


      <400> 2363
 gaagtgcgct ggaattcccc tccaacggat tccctctccc ccgacggcgg cagcatcgag     60
 ctggagttct acctggcgcc cgagccgttc tccatgccca gcctgttggg agctccaccc    120
 tactctggcc tgggcggtgt aggggatccc tatgcgcccc tcatggtgct gatgtgccgg    180
 gtgtgcctgg aagacaagcc catcaagccc ctgccttgct gcaagaaggc cgtgtgcgag    240
 gagtgcctca aagtctacct gagcgcccag atccagtgcc ctacctgcca attcgtctgg    300
 tgttttaagt gccactctcc ttggcatgaa ggtgttaact gcaaggagta caaaaaagga    360
 gacaaattgt tgcgtcactg ggccagcgaa attgagcatg ggcagaggaa tgcccagaag    420
 tgtccaaagt gcaagatcca catccagcga actgaaggat gtgaccatat gac           473



      <210> 2364
      <211> 2150
      <212> DNA
      <213> Homo sapiens


      <400> 2364
 agaggcgccg tcttcccggg tcccgagcac tctgtgccgg aggaatcagt gacattcgaa     60
 gacgttgccg tggttttcac agatgaagag tggagtcgtc tggtccccat acagagggac    120
 ctctacaagg aggtgatgct ggagaactat aacagcattg tgtcattggg ccttccagtt    180
 cctcaacctg atgtgatttt ccaattgaag agaggggaca agccgtggat ggtagatctt    240
 catgggtctg aggagagaga atggccagag agtgtctctc tagactggga aactaagcct    300
 gagattcacg atgcttcaga caaaaaatca gaaggatcat tgagggaatg ccttggaagg    360
 caaagtcctc tgtgtcctaa atttgaagtt catacaccca atggcaggat gggaacagaa    420
 aagcaaagcc cttcagggga gactcgtaag aaatccctct cccgggacaa aggcttgcgg    480
 cgacggtcag ccctgtccag ggaaattctc actaaagaga gacaccagga atgcagtgac    540
 tgtgggaaga ccttttttga ccactcatcc ctcacccgcc atcagaggac tcacactggg    600
 gagaagccct acgactgccg cgagtgtggg aaagccttca gccacaggag cagcctcagc    660
 agacatctga tgtcacacac tggggagagc ccctacgagt gcagtgtgtg ctcaaaagcc    720
 ttctttgacc gttcgtccct aactgtccat cagcgaattc acactggaga gaaacccttt    780
 cagtgcaacg agtgtggaaa agcctttttt gaccgttcat cccttactcg acaccagaga    840
 attcacactg gagaaagtcc ttatgaatgt catcagtgtg ggaaagcctt tagccagaaa    900
 agtattctta ctcgccatca gctaatccac actggcagga agccttatga gtgtaacgag    960
 tgcgggaaag ctttctatgg tgtctcgtct ctgaatagac atcagaaagc tcatgctggg   1020
 gaccctcgct atcagtgtaa cgagtgtggc aaagctttct ttgaccgctc atcccttaca   1080
 cagcatcaga agatccacac tggagacaag ccatatgaat gcagcgaatg cgggaaagcc   1140
 tttagccagc ggtgccggct cacgcggcat cagcgtgtcc acacgggaga gaagcccttt   1200
 gaatgcactg tgtgtgggaa agttttcagt tcaaaatctt ctgttattca acatcaacgg   1260
 cgttacgcca aacagggaat agactgagtt gggcaaaagc ttgggtagga caagaacttc   1320
 catacaaatt tgagatagat ctcgcctgtc ttaaagctgc catttgctca ttctacccac   1380
 tctggctgcc gttgtcctgt cctgcttctg cgccagagtg tttaataagc actcccttcc   1440
 tgctgtgtta cagaactgta ggggaggcca tggaaatgac tctaaagata caaaattttg   1500
 aagaggtttg tcagacaata ggatagatgt taggaggaga cacacctctt gtctgagaac   1560
 ctaggcccca ggtatcactg cactttaaga aactggaggc tgcaacagga gggaaaggca   1620
 gaatgatatc acagcagtac tatttttttt tttcaaaaca tttgttttga tggctgttag   1680
 tccccctctc ttggagcatt ttggggcact aatcttgttc tcttgtgtcc cagcttttag   1740
 acctcttact tccactgcta gtagctagca cttactgagc acctgcaatg aggtaaagac   1800
 tcagctaagg gttttacagg aagtagatta attgatcctg tcaccaacca tatgaagtag   1860
 gcactgttac catctgcatc tccagatgag caccctgagg tttagagaga ttaaatcact   1920
 tgcccaaggg tgaaccagct ggtaaaaggt gatgccaggt cttgaagaca ggtccacctt   1980
 caaaatctat tctctttacc attatgctcg atggtttgtt tgttttataa tttatgtata   2040
 tgtattatcc tctcaactag attgtaagca cttggaggtg tgacttacag gtctttgtat   2100
 ctcacacagt gccttgctaa taggtgctca ataaatattt atatgagtga              2150



      <210> 2365
      <211> 732
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(732)
      <223> n = a,t,c or g


      <400> 2365
 ttctacttta atgtttcctg acaatacttg atttgtgggg aggggaattt tctgtatctt     60
 tcctctctct ctctagccgg gcctttccac cttatgttat atatagaatg taagtctcat    120
 aagctggttg ctcccttggc agttttcttt gctctgtttt tcctccttat atttttttgg    180
 gtggcattct cctatccctt tgagttactc ttcttgcagc tcagatcacg tcaagcagat    240
 attggggttc agtgatgtct ggtgatgtct ggaagtgccc catgtcagaa ttccagctgt    300
 tcagcagcac aggaagattg tacacctgca actgtgcgaa tggtcctgtt gcctcctgca    360
 ttttggcctc tgttctatta aggaagagta aagatggagc tcctcctgcc tccatcacaa    420
 aagcacatat catctgtccc tttggatttt acttccaaga cgtgtgtcat ccccaacgtg    480
 agttgcctta tggggccggc agaacctcag gtatgtgcct gaaaaggaaa atatccttgg    540
 ggaaaatctg ggaggaaaat tttttttttt ttccggggag gttgcggtta tccgggagca    600
 ctacctaaaa aagtagggca gtccacccac cccccccccc ctnccccccc cccccccacg    660
 ccgccaacct aaaacgnnaa aaagggcgtc ccgaaaaaaa cccccccccc cccctccccc    720
 cccccttgac ta                                                        732



      <210> 2366
      <211> 833
      <212> DNA
      <213> Homo sapiens


      <400> 2366
 agagctagac ctgagcttca ataccctgaa tccatgctta cctgttcaca aatagctcct     60
 gtcatggtga ctgggaaagg cctgacattc ccgcggccca agttttcgcg tttcctctgg    120
 ctgctgaaaa gcttcagctc cctcttctct tcctcatcca gggagttgca atatcgaacc    180
 tcattgtcat gtggcggcag ctggtgtagt agctgcttga ttcgcagttt ctctccagga    240
 ctgttgacat aagggacttt ctcttctggg agacagctat agtactggtg tacctgttca    300
 ggcttcagac ccggcgggac ccaggcatac tcttccaaag cacagcctga gtcatcatct    360
 gaggtcgagt tcctctgaaa gtcaaacatg agtttgctga tggtcttctc catctccagc    420
 ggcatcactg tcaccatgtg ctcctcctgg ggacacttgc agtgcaggca gatcttcctc    480
 cagggaggat gaaatgccca gtctcgtagt aagtgtgggc cagacccttg gagcttgtca    540
 attgtcccag ttcactttct ccctggatct gacttataag aacgcaagca ggacctcagg    600
 cagccaaagc atcttctcct caaaccccct tttcagtctg atcccgtcat ggaggtggca    660
 accgagtcga gccgagtggc tcctcattcg gtcagggcaa gcagcactgc agaaaccaga    720
 gtatcatagg aaaaacatca agcaacatat agaaagtata acccctgctc ttcctgtgtg    780
 tgagcgcgag tactcaaaaa ataatgtgct cgacctccag tttcctctta act           833



      <210> 2367
      <211> 816
      <212> DNA
      <213> Homo sapiens


      <400> 2367
 atgctggcag tcctcacagc cttcgctcgc tctcggcgcc tcctctgcct gggctcccac     60
 tttggccgca cttcaggagc ccttcagccc actgctgcac tgtgggagcc cctttctggg    120
 ctggccaaga ccggagccgt ctccctcagc ttgcagggag acttgtcaca gactttatct    180
 tcagtagtag gtagagacag gaatgctaag aaaggagaga tgatcatgct ggtaaatgtg    240
 gctggaaccc atgcaaatgg gctttctcca catgatggag aagatggctg ccaggacatc    300
 agccatattg gattagggca cactcaagtg atttcatttc actttaacta cctccttaaa    360
 ggccctatct tcacatacac ccatattccc agggactgga gaactgcaac ttccagtgag    420
 tccctctgtg tgtctggatc agggaatgca attaaagccg agtacttcga gtcacctttt    480
 aaaaacagtg aagccacgaa tgaaacgaca gtccttgctc cacatgaaac aatctttcga    540
 gccgaagatc tatctgtgat tcttaaagcg tatgtgttgg tgacgtcctt aacccctttg    600
 cgtgcattca ttcattcgac gggcacagtt tggaatccac caaagaaaaa acgcttcact    660
 gtcaagcctg cttctccctg gagccatcaa gggaaggtat atgctgggat gaggatggga    720
 cccagttatg gacttgaaaa gagcaagtgt tgtttctctg aactggatcc tggaagtgta    780
 ttgcccgtga acttcacaga agctcttaaa aattaa                              816



      <210> 2368
      <211> 1016
      <212> DNA
      <213> Homo sapiens


      <400> 2368
 tttttttttt ttttatgttg ttcttacttt tattagaaca ttgactccta gagctggaat     60
 tgtatcttgg atttttggtt ccgctggtag cacaccgtgc tcaataaaaa ttaatccatc    120
 aatcaacagg acagaaaatc ccatcctgcc agaagcaata cttcctgttt gtcccataca    180
 aagccaatta gagtgttagg atgttgtaat ggagacagaa actaaggaaa gcggcaaaaa    240
 taaaaaaatt cccccaaaac atcaaataga aaatgtaggg gtagggggat tgggggcaca    300
 agatgggttg aaccagatag ggaagattcc cccagtgttg tcctgctccc agtccaggtt    360
 tgggacaatg ccggcagcgt ttccctgtgt ctttccccca caaagtctcc aagtctctcc    420
 tcaaatgagc tccaaggctt gggagaaaca atctcttcct ctgcccgggt tgcgtggatc    480
 tccagtggaa aggaagaacc ggaactatga tttgtgcctt ccttattgcc tccgaaatat    540
 ttttaactgc agaggaaagc ctgtattatt ttggagaaag gcgaacagat aaaacgcaca    600
 gcagtaaatt tcagggacta gaaactcctt ctcagtagag acaaggtttc accctgttgg    660
 cgaggctggt ctcaaactcc tgacgcccag tgatctgccc acctcggcct cccaaagtgc    720
 tgggattaca ggcgggagcc accatgatgg ccaacttttg aattctgaac cagttgattg    780
 agtaccagag ctcttcaata ccttgaagaa agattcaggg gagagccgtt gtgaacagct    840
 tgccccaggg aaaggacaag gctgagagaa ttccagggct tccttgagaa aacagaattg    900
 aggaaatgca aagtgaagaa ttctagcatc aggaacaaga gaagaatgat ggaaaacctg    960
 ctactgagat atgttggata ttttgcacaa gtgaaacatc tctacaactg gaatct       1016



      <210> 2369
      <211> 380
      <212> DNA
      <213> Homo sapiens


      <400> 2369
 gtgagccacg cagaagacgg gtgatttctg catttccatc tgaggtaccg ggttcatctc     60
 actagggagt gccagacagt gggcgcaggc cagtgggtgc acgcaccgtg cgcgagccga    120
 agcagggcga ggcattgcct cacctgggaa gcgcaagggg tcagggagtt ccctttctga    180
 gtcaaagaaa gcggtgacgg acgcacctgg aaaatcgggt cactcccacc cgaatattgc    240
 gcttttcaga ccggcttaaa aaacggcgca ccacgagact atatcccaca cctggctcgg    300
 agggtcctac gcccacggaa tctcgctgat tgctagcaca gcagtctgag atcaaactgc    360
 aaggcggcag cgaagctggg                                                380



      <210> 2370
      <211> 422
      <212> DNA
      <213> Homo sapiens


      <400> 2370
 catgcagaag agacataatt gcaaaaaagt tcatgcctta cctccagcag tcttgggctt     60
 ccagagggct tcaggctgtc gatttgcgaa caagagatcc aggattacgc attttggggg    120
 ccgaaggctc agcctgactc ccgcttcgga ctcggcaggt gtctagcacc gcgggcccag    180
 gcggaaggcg ctggcgcagc gcagagcagg gactccactt atcgaggact ggaaactccc    240
 cttgccgccc ggcctccgcg ctgcgctcct tgctgtcacc gctccgagcg acgcaggcac    300
 gctccccgct gcctcctagt cctggtgggt ctctctgctc tcttctccgg gttcgtccgc    360
 tccctcacag accacaccct gtcacctcag caaccctcca ctccttcctc tttgacacga    420
 aa                                                                   422



      <210> 2371
      <211> 423
      <212> DNA
      <213> Homo sapiens


      <400> 2371
 ttcggagcag agagaacagc gcccatgagc cacagggctc atacatccgg agcctatcac     60
 cactccgcat cttaagctcc cgggatgacc gcggactggc ggcccaggac cactgctcca    120
 gctgtttccc caggtaatcc acctgccttg ggttaccttt tagcgcggcc cagttagccg    180
 caaccagcca ccatttaccc gctttcccca aaccaggaaa accacagaaa cgcatgtgcg    240
 cggccagtct cttccacgcc cgggaacgca gagcttacag accaaggccg cccaagtccc    300
 ctcaccccaa aggctaccca agaaccccga gtaggctgtt tggctgactc aggcgcccaa    360
 cgcccacccg aactgagtcg ctagggaaac tcccaactgc cagacgaaat cgtcgacccg    420
 gga                                                                  423



      <210> 2372
      <211> 792
      <212> DNA
      <213> Homo sapiens


      <400> 2372
 attgagacca tagagagccc ggcggaattc atttttttct tcaagctaga aatattacgg     60
 cttatgaagc atgtgagaca gtccccgcca tgtgctgatt acacagaccc ctgtaccaga    120
 aatcagaagg aaaggagtca gacttgaatc aaagaaatgt ctctggcaca caggccttca    180
 aattgatggc tggagcctgt cttttaagaa caaattaatt cattatagga aaaaccctaa    240
 ctaattgaaa ggtctaaatt cttcaggttc tcttgtgatc ctgggaaatg ctagaccgtg    300
 agcatcttga tggaggatgt gaactgccac ttcctcacag gcagcaggca ggtgctgaat    360
 aagtgcttgc tgaatgaatg aatgaatcac gccaaggggc atgttacctg ttccgccaaa    420
 atctgctgct gctgctgctg ctgctgcctt tgctcccgca ggaactgttg cttctgctgc    480
 tctatcaact gggcccgctg atcaatgagc atctgcttca tgatggctgc ttggggctgg    540
 ctgcccagga agccggggcc tgcgggactg gctcctgaga ccatgccacc tgagcctggg    600
 ggcacggagg actgcatggg gcctgtggtt cggggaagtc caactggatg ctgctcctga    660
 ccgtgggatg gaagtgcagc gtaagccatg ggctgattca tcactccttt ctgcttcatg    720
 agaagcaggc gtttctggtc ttcgctcagg tgtgccctgg gggcctgaag ctagaagagg    780
 cggacgcgtg gg                                                        792



      <210> 2373
      <211> 1778
      <212> DNA
      <213> Homo sapiens


      <400> 2373
 tttttttttt ttttttttaa acttttggaa aatccagggg ttttaagttt aattattttt     60
 taatcatatt tcctgaaaat gttataatat ccaagactgt cctgataatg cttttttaat    120
 actttcccag ttctgcccaa cattcctgtc atgcatccct taataacaat gctcatccca    180
 gaaccgggat gggggggcgg tgaggtgggg ttggtggggg gagtaccgtt tctgagctag    240
 ttaaaggtca ctgaggaggg cccatacctc aatgtgtgtg gagttaccaa ttaggaaatt    300
 agtccatgga aggaccatgt ctacccacag atatcttttc ctcacaattt aaaattattc    360
 catttcttcc taccagtcct cctttctatc ttttagttcc attttaaaat aacccttgca    420
 tcctacatac ccatttatct tggcttcctt tttctccctt ttggtcccac taggtatagg    480
 ggattgtggc ttcggtaaac tatcctgatg tggagagaaa aaaatcaaaa tgtgatcaat    540
 aataatagtt taacaaagtt aagattgcat gctctaaaaa cataagtgat taactggttg    600
 gatgcccaaa agcactcttt gtttcctttc caagttgatg actcttccgt atatttcctt    660
 ttttcccata tgggcaccct tggcctttta aaggtatcaa agggcaatag ctcaacagct    720
 tcaaagagat gccagctctg tgggctggag gacacagcaa atgattatgg cttggcttct    780
 gacactggaa ccaagccaag tctatggaac actgctatgt gtttgactgg ccatttctgc    840
 ctaatgtcac tacaaatctt tctgacttca ttttccgcca tgggtagata tgcttcatat    900
 tcgtaagcta atgacttttt tccccttcaa aggtattttc tgtaaggccc ttccaattgg    960
 ggatattgca ccacaagagc ggagaaatca ccaaactgtg agacttcatc tactgaaaag   1020
 tttctcggca gtaaagttta taacatcttt agatttctct tcaacttcat cccatatctt   1080
 tcctagatgg gctcaaaaag cactatcctc cactaatggg ggggataacg gcaatttcgt   1140
 ctcccaggct gaagcacgag gagctgatct ccaagctcga catattcttg acgaacagca   1200
 aatattatct gatttctaac atcagccaac tccaggatgt cgagtttcta tctccttcca   1260
 cagctgcaac gcttttattt cttgaggcac agaaatggtc tctgaacgaa ctcctgttat   1320
 ttcagcactt tttgcaaaat acaatacttc aacctgtatc cgtgcaaaca actctttacg   1380
 aaataattac aggtttgcaa atgatcaagg gtgtagaaat ccacagatga agcacagttc   1440
 ttcacaagaa ttctccatga ggtgcatttc tttttagatt aaaattttag cttcatcaaa   1500
 acgaataatc tgggaaagag gtggtcataa aagtgtgtgg gcgccttcac aacgagtccg   1560
 tccttgctgc cgtgagctga caagagttct cggagaggac ccgacttctg ctggggcagt   1620
 cgcagtaaag cccggagaca ggaagggccc gggggcgggg gcgggggcgc ccccgaaccc   1680
 aagacgccgg ccaggttggg ggctagtggg gaggtccgac tgaccaaggc caggcccgca   1740
 cgcacacccg ccacccttac ctggcacagc ggcaccat                           1778



      <210> 2374
      <211> 412
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(412)
      <223> n = a,t,c or g


      <400> 2374
 atgaaggcac tcctggccct gccgctgctg ctgcttctct ccacgccccc gtgtgccccc     60
 caggtctccg ggatccgagg agatgctctg gagaggtttt gccttcagca acccctggac    120
 tgtgacgaca tctatgccca gggctaccag tcagacggcg tgtacctcat ctacccctcg    180
 ggccccagtg tgcctgtgcc cgtcttctgt gacatgacca ccgagggcgg gaagtggacg    240
 gttttccaga agagattcaa tggctcagta agtttcttcc gcggctggaa tgactacaag    300
 ctgggcttcg gccgtgctga tggagagtac tggctggggc tgcagaacat gcacctcctg    360
 acactgaagc agaagtatga gctgcgagtg gacttggagg actttgagaa cn            412



      <210> 2375
      <211> 711
      <212> DNA
      <213> Homo sapiens


      <400> 2375
 ggaaaatagc agattttggg ttcagtaacc tcttcactcc tgggcagctg ctgaagacct     60
 ggtgtggcag ccctccctat gctgcacctg aactctttga aggaaaagaa tatgatgggc    120
 ccaaagtgga catctggagc cttggagttg tcctctacgt gcttgtgtgc ggtgccctgc    180
 catttgatgg aagcacactg cagaatctgc gggcccgcgt gctgagtgga aagttccgca    240
 tcccattttt tatgtccaca gaatgtgagc atttgatccg ccatatgttg gtgttagatc    300
 ccaataagcg cctctccatg gagcagatct gcaagcacaa gtggatgaag ctaggggacg    360
 ccgatcccaa ctttgacagg ttaatagctg aatgccaaca actaaaggaa gaaagacagg    420
 tggaccccct gaatgaggat gtcctcttgg ccatggagga catgggactg gacaaagaac    480
 agacactgca gtcattaaga tcagatgcct atgatcacta tagtgcaatc tacagcctgc    540
 tgtgtgatcg acataagaga cataaaaccc tgcgtctcgg agcacttcct agcatgcccc    600
 gagccctggg cctttcaagc accagtcaat atccaggcgg agcaggcagg tactgctatg    660
 aacatcagcg ttccccaggt gcagctgatc aacccagaga accaaattgt g             711



      <210> 2376
      <211> 4386
      <212> DNA
      <213> Homo sapiens


      <400> 2376
 aatctttttt tttttttttt ttgcagtaca tgaatgtttt attcttcata aagtgcttaa     60
 aacatgaaga agaagctctt tataaagagc cttaactagg aagacaaaca gcaaagcaga    120
 accatgcctg ctccctgccc aacccacctg caactttcct ccaagtcgtg gctcggagaa    180
 gaaacatcaa caagggaccc tgggcttcga ttcaaaaact tcctctgaag ccattccatg    240
 ccctgggatt tacgggaggc ccacaaaggt catgggccag ggctgggagt gaattaaagc    300
 ccaggaggaa tccccagtag gggggggtga ctccccctct cttcagaaaa gatacttact    360
 ttctctaatt acccaatgga cccccaaaag catggactgg aaaccctggg gggaccagtg    420
 ggatactttt ctcagatttg atgagtggag tttaaggtag gtaacgttac aggggctttc    480
 ctccatgtgt ggcgctcctc tgctccatcc tggcagcaga cagacatcac ccagagggca    540
 cgtgtctgcc tgaggccttc caaaagcaag cccacaggcc ctctcctgaa gaagtggtgg    600
 tcccagagga gctcttgcct cctcactaag ctgttaagta tccttcttca gcacctcatc    660
 accccccatt tttgctaatt cagggtgccc caagctgcca aagttccctg cagatgcctt    720
 ggggaagcct accatgtttt ctacaagcaa accaggggct gggccaaagg acagatactt    780
 catttcaaag tgcactgcag ccaagccagg caagcccctg gggcagaagg gacaggctga    840
 gatagcagct taatggatgg atgggaggac aacaaaggct ttttcctaag tataggtgtc    900
 tcccaaaggc atagtgggac ctccctcttc caggcaagct gactggtcta gtatggctaa    960
 gtcctgaggc cagacaatga gagtgagcag ggcagcccca ggcctgcctg cccgcctgcc   1020
 cagcagtgtt tatcctggga tcctcctatt ggggttgagg gaggggaaga cagcaggaag   1080
 gttgagggag cagcaacttg gccagaccaa gagattaact ttaggggaag ggaacagccc   1140
 acagcagtgc tgtccattcc cattcccagg gccctgagag agccatccct atgtattcaa   1200
 caggtgggag ggggacgcca cacagcggga gaggtcgaca tccaggggct cttgaccccg   1260
 cccaccaaag gcacatttta attggtttcc aaaagttcaa accctgcagc aacacagagt   1320
 tttggcatct ggacaggcaa caagaataga catggaggct tgatccccaa atcataagca   1380
 gtcccaagcc ccagcctgga gggacctaca cattggaggt ggtcaagagc tcgaaaagca   1440
 aaaaggtgct ctctccgcac ccgcccctgc gccccacaca ttcccatgtg acactcgtgg   1500
 aaaggtcaga ggggtcaggg agcagcctga agcacacaca tcatccacca ctgtccacat   1560
 ggcactcgcc ccacaaacag ctccagactg aagcagactc aggacatggc agagactggc   1620
 ccagaccaca caggcttctt gctctcaggg gaatgggtgt gaggctgaag aggctggttg   1680
 cccgtaactc acagacaaac aggcagcgtg gtcattgtcc cagtaatact agaagcccct   1740
 ccagggactg gagggaaatg aaggggatgg ggctttggct gtgggaagaa atggctgacc   1800
 atccttgggg gataataaag tatgtgctag caaccagtct tgtcccagat tactgcatca   1860
 agctacagtt cacccctgct ctgtcttggg ggaagagttc caattccctg gggcccccaa   1920
 agctgaggga tatgaaaaca ggcaggtggg aaagacccag ggctcccaaa gacacacaag   1980
 ttgtgcacag aacctgatgc ctccaaaggg aatccagagg gcccccttcc agcagcccca   2040
 gttgaggcag gagggagagg agcaaggagt gacaaggcaa gacagacgat gccccactgc   2100
 agatgagaga gttcaggagg agagagggca ggcagcaata ggtccatgcc aaccctcctg   2160
 ggggtagggt gaggaaggct atttgggggg gcccgggggg atctgcagca gcgtgggtga   2220
 ggtctccatg atccgcacca gcagccggtc gatgtagctc tccagctcct gcacatgctc   2280
 gtcccgctgg ctcagctccc gctcccgctg caggagcagg ctgatgagct catcgtgggt   2340
 caggtggtag tacttggccg actggtccag cacagctgag tccttcagcc ttttggtgtc   2400
 caccatctgg ccagcctggg gggcctgggt cacaggctga atgctcccag atgtgactgt   2460
 tttgagcttc tccagcccac tgctcagggc tatgctcaga ctggagcggg actgcttcct   2520
 gtcggggctg ccctccacag gggcggcact gaggggcttc acggggtggg gactgggttt   2580
 ctgagtcggg tccttggctt ctctcaagcc aaaccagcta ctcttggcct tttcctcccc   2640
 actggatgag tgatgtgggg aggcccccca ggatgggacc cccccttttc cccccagaga   2700
 gcttcggcga cccaactcgc tccgacttag gccttggtgg tggtggtgga agagacccat   2760
 ccggggcttg cgttcctcct tccgggctcc ctccttctct gccacagcct cagaggaggc   2820
 cactatgggt gtggcaacct ggactggctt gccctctggt agccgggccc ccctcctcct   2880
 ctcccagggt ggctggcccc aggggccagg actttagcct gagcactcag ctcctcctgt   2940
 ccaagcactg cctctgagct gctgttgcta cgactgcctc tgggccaggt gtcatctgtg   3000
 gaacgaggcc cctcctcgga gaaccgggaa gagacagctt gcaaggagcc agaggatgga   3060
 agcgagcccg agatggagct gcggtgccgc acagggccct ggggctcctc attgtaaatg   3120
 tggctcccat tgacacagag cgaagagcgg gaggcagcat ccaggtggcc ctgaaggtcc   3180
 agaagggccc gaggaggagc cactcgcatc tggttggcct catcgctgta ggtcctctta   3240
 tgggtgaaca gcttggggga ctgtgcagag tccctgcccc cttcagtgga cagccagctg   3300
 ctacggcttg gtgagcgggt gaggagttcg gcgccaggtc cctggtaggc caagctcccg   3360
 ctggctgagg acagggtgct gtccgagccc agcgaggtgt tggactgggt cagggacgac   3420
 ttgcgcagct tgttgcggag gaagaagcct ttggctttgc ccatcttgcc caggctgccc   3480
 aggtcaggat cctctatggc gctgcttggg aggatggcag aggcagattc cagatcatac   3540
 ttcttcttgc ccttcatctt gtccctgatc ttgctgaagg gagaccttgg cttgtccttc   3600
 atggacaggt caaacatact ggcgctcagg ttgttgcgcg tgaactggat ggtgacttca   3660
 atctcgccgc gttccttctc cttcttgcct ggcttggagt gcagcttgta ccactgcgtg   3720
 tgctgggcgc ggcctgcgcc gaagacctcg tccagcgcca ccgtggcctg gcccaggaac   3780
 ttgtcgacgc cgatgagcga gcggtgcatg gtggtgagca ccagctcgca ggcggcggcg   3840
 gagctcgcgg cccagggcgc cgggcccgcg tcggcctcct gcgcccgcag caggccatcc   3900
 agggcccccg gcggcagctc gaaggagcac tcctcacgcc actcgggaca gccgtgcgtc   3960
 ttctccacca ccgacgtact gtacttctcg cggcccacct ggatcaccgt gtacgcgtcg   4020
 ctggtgctgc ccgctcccga gctcttgccc cgcagcccgc gggcccgcag caccgtcacc   4080
 tggacgtgcg tgggcagcca gcgggaaggc cccgccgccg gctccgcgcc ccgcaccagg   4140
 gccatggcgg agaagcgggg ggcgaggtct ggccgagccg gtgcagaccc caggacctgg   4200
 tgacaaaccc ggccgcggca gaaggcggtc aggaaccaac tctgagcgcc gccgcagctg   4260
 cgggctgggc tgggccgggc cgaccggccg ccgcctcccc gcctcaccgg gccgctggcc   4320
 gcgggccgcg ccgcgacgtc agcgccccgc cccctgcccc gccccgcgcc cgccgcccca   4380
 accggc                                                              4386



      <210> 2377
      <211> 607
      <212> DNA
      <213> Homo sapiens


      <400> 2377
 ctggcaaggg ggcatcctgg gctctgatcc caccccaccc cttacttccc caaacctgct     60
 gcagacagcc tgtttccggg aggagcggga tgtgctcgtg aaaggggaca gccgttgggt    120
 gaccactctg cactatgcct tccaagacga ggagtacctg taccttgtga tggactacta    180
 tgctggtggg gacctcctga cgctgctgag ccgcttcgag gaccgtctcc cgcccgagct    240
 ggcccagttc tacctggctg agatggtgct ggccatccac tcgctgcacc agctgggtta    300
 tgtccacagg tggagcccca accccgctgc cctgcccaac cccgctgccc tgcccaaccc    360
 ctgccagctg tgctggggac agctgatgtc agctgagcac tcatcatgtg ccaggcactt    420
 ctctgggtgc ctcatccgtg tgcttccttg gaatcatacc aaagagccct ctgtggcagg    480
 ggctgctgct gtgtccggcc tgcagctgag gggggatgtc aagccagaca acgtcctgct    540
 ggatgtgaac gggcacattc gcctggctga cttcggctcc tgcctgcgtc tcaacaccaa    600
 cggcatg                                                              607



      <210> 2378
      <211> 1158
      <212> DNA
      <213> Homo sapiens


      <400> 2378
 atgactgcag atgctgtgct catcaaaaat ggtagtaaag atgctgactg ggaatatgaa     60
 gaaggtgata aattagaaga gtttcttaga tcgctaaaca gcagtaagcc tctctacctg    120
 ggacagactg gcctggggaa tattgaagag cttggaaagc tgggactgga gcctggggaa    180
 aacttctgta tgggaggacc tggcatgatc tttagccgag aagttctcag gaggatggtg    240
 ccacatattg gtgaatgcct tagagaaatg tacacgactc atgaggatgt ggaagtagga    300
 agatgcgttc gccgttttgg tgggactcag tgtgtctggt cttacgaggg aaggtgttca    360
 ttcagagtgg ttcctgacag cgcaatagaa ttttcaatgg actttgaaaa aattctgatg    420
 ctggacccca cccttcatcc gttatgtcaa aatctcttac agaggcttaa caccatgtgg    480
 aagccaccaa acgtggggct tgtaccctcc aaagcaacag cccaagctgt acgttggtcc    540
 cttttagcca tggctagagc tggagcagcc acaatgccag gagccctgtc ccaaggctgc    600
 atagaagtta gtaggctgct gaagaaatta ccagatgatg aaggtatcac catggacaca    660
 gtaggctttg ctcctttgtg cctgtggcag agactgacct tggctaacca tcagagatat    720
 tttgcagatg ggccccagcc agtgtgtaac cacatgcagc ctgccccgca ccactttgcc    780
 agcatgcgtt catctgcagc atcgcccacc agtttgccag catttgcaga ccctgctgct    840
 gtacccccac tggagcatgt gtatgtgtgg accctgctgt tatgccagcg ctggtgcaca    900
 tacatgtaca tggactcaac tgccaccact ctgacaaagc actgttgctg cccacccccc    960
 atacccccca ttggagtgtt gttgccagca gactggggac acattggccc ctccagtgat   1020
 agcaggtcag agaacaaagc catggggtct agtcccagca cctagggtta gagcatgcag   1080
 accaagagtg ctaaactgag ccttggcccc ctgaaatcat tgagaaatga agccagttga   1140
 tggaacccaa cttatacc                                                 1158



      <210> 2379
      <211> 552
      <212> DNA
      <213> Homo sapiens


      <400> 2379
 tacgaagctt aacccaaaga tcatggatgt gggctggcca gagctccacg caccgcccct     60
 ggataagatg tgtaccatat gcaaggcgca ggagtcctgg ctgaacagca acctccagca    120
 tgtggtcgtc attcactgca ggggcgggaa aggacgcata ggagtggtca tatcatccta    180
 catgcatttc accaacgtct cagccaggta ggatgaagat gtcagctcgc tgtcttgagg    240
 tgctaaaagc tgagcctgca tggggctgaa ggctgtctgc gcgggagctg ttctggatac    300
 caagggctcg gctgacctgt gtttcccatc ccccagtgct gggttggtca gtgcctagaa    360
 acccagtttc cagttaagcg tttacacttg tgaaagtggc attttccagg ttgggtgact    420
 gtgtgattga ttctaagtac ttccatggag gcattaaaaa aataagtgac cccactgtcc    480
 cttgttcttt aatagagaat tctctaataa aaaataacag agataaaagt caccattatg    540
 aaaaaaaaaa aa                                                        552



      <210> 2380
      <211> 328
      <212> DNA
      <213> Homo sapiens


      <400> 2380
 accgcttaca cacagcaaac ctgggcgatt caggcttcct ggttgtcagg ggtggtgaag     60
 tcgtgcaccg atcagatgag cagcagcatt acttcaacac tccattccag ctctcaatcg    120
 ctccccctga agccgaggga gtcgtcttga gcgacaggta atctcccctc tcagccatta    180
 agtgtgagca ggacgtggct cattcatagt cccctcctgt cccccttgag tgcagtgagg    240
 taggcatttc catgaaaagg aatacactga gaatgttctc atcaagagga ccttttagtt    300
 taactttgaa agatactttt ctggaact                                       328



      <210> 2381
      <211> 1260
      <212> DNA
      <213> Homo sapiens


      <400> 2381
 atgcctgcag aattcttcca gcgttgttca gtgattatgg ttcagctgcc atggaaagaa     60
 gcccatgtgg agagaccaca tggggagaga gactacactc cagacttgca gccagacatg    120
 tgggagaagt ttcccgggct gagacgcgcg cttcgccccg tggtgaagac gctgctggtg    180
 cagctagaat ataggcaggc agaaaagtgt gaaaagagag actggcctag cctcccagac    240
 tacatctttc tcctgtgctg gatgcttcct gctcttgaat atcggactcc aagttcttca    300
 gttttggaac tcagactggc tctccgtgct cctcagcctg ccgacagcct attgtgggac    360
 cttgtgattg tacctataac tagtctaaag tcctggcaga cccctagagg tgaagttgag    420
 ggtgtgaccc atgaggagat ttgtgcatct ttgaagagcc ttgcagttgc tcttctctct    480
 atgtcagatc taacagtggg aaccccagtc actcaaccac aaactttaaa tacaatggga    540
 ataattggat cccgaggtgg caggggtcaa gtggcagcac tcaaccgtca aaggcaagtg    600
 ccagaattaa taattggcat agacatactt agcagctggc agaaccccca cattggctcc    660
 ctgaatggta ggggatatat caactctctg gctttgtgtc ataatcttat tcggcgagat    720
 cttgatcgct ttttgcttcc acaagatatc acactagtcc attacattga tcacattatg    780
 cgattggatt cagtgaagga taagtggctg catttggccc ctcctacaac caagaaagag    840
 gcacaatgcc tagtgggcct attggatttt ggaggcaaca catttctcat ttggagacag    900
 cccttggcct gttactgggc tttggtggaa actgaacatt tgactatggg ccatcaagtc    960
 accatgcaac ctgaattgcc tatcatgaac tggctgcttt ctgacccatc tacgccgtta   1020
 aggtttgtga ctgggggcct gcaaactaaa cagacaaaag acagattggc aaagaaagga   1080
 cagattttta ttgatgtagt acacaggagt tcacagaaaa atatgcttca aggaggaagt   1140
 tttgactcta tagagccaat ggatgtggac cctggactta gaaagagatt tgtaaacaaa   1200
 ccagagaaca ccgaagagct gctccttcgc actgaaatgg tttgctggct ttctgcctag   1260



      <210> 2382
      <211> 4061
      <212> DNA
      <213> Homo sapiens


      <400> 2382
 tttttttttt ttagggggtt aaatgtttat taaatcaagc ttttaaatta tatatccacc     60
 tacagtctat aaacaaatat agtacacatg tatgtaaaag gctagcagat aagaaccagt    120
 ggaaaaacta aagttccctt tgcacaccgg cacctcatca caacaccctc ttggtgtgga    180
 tgccatgggg ccatgctgta gtcaaaagtt aaatgaaaaa ccacaagttt agtttgactc    240
 cgtctcctag ggtggatttc attcagatat ttgttccata ttataggagg gtggatccta    300
 gcaaggcaac agtgtagttt ttacattcac agattggctg aagtagtaca aattgagctg    360
 ctaatctagg tgtctccctc cctgttacca tacttcataa gaaatgtgaa ttaaaatgaa    420
 caatggacca caggtggtta taaaaataga taactcgcag agtcataaat atctacagtt    480
 agtagagcag aaacttctaa aatttacctt tttccataat gtgcagaata tcctaagtat    540
 gttcaagaga cacagtcagc agacttcaga gtggtaatta caagggcatt tgtaaagaaa    600
 taacactcga gtacaaaccc agagtaagaa gctgaatgca gatgaaaata cgcaaaacac    660
 gcaaagttcc aactcctcac atctcattat gctacttact agacaccaca attagcttac    720
 agccctttat atatctttta aagtaacttt ttgttacctg tgtacaaact ttaacaaaga    780
 tttttcatga gacaagcaaa gtgggttaat ggtggcgcta aaactgctga aacttggagt    840
 gttttgtgtg ctttcgtata cttctgtgta tggggcttta aaatgctcca aaaatgtttt    900
 ggatagagtt tttaaaattc ccatgaaaat ctattttata atcatttcaa ggtatagaaa    960
 aaaagaaatc ctaaactggc attgagggac aggcccaaat ctcacaaagt aacttaaatt   1020
 ctaggaatat ataaattaca ttcatatgtt catttaacac gtatcaagtg ctatgtaagg   1080
 taactgtaat ggattctgaa gccaatctca tttaaaacag tacagtaaat cccattctaa   1140
 ttctacaatt aaagcactta ttccaggtaa tgtgcgtttc agcaaagctg acatcttgta   1200
 caacagtgtc accttaaagc ttcatcaaag attcacagca ggcctgaact gtaaaagttc   1260
 agaaccaaca atgccacagg tagttattca tcctaatttc tcgcagggag tgaagggtct   1320
 acttgagtga tcctaaggtc acctaagcct agaacagtgt tccctgaaaa ctccagcaag   1380
 tttcctcacc aaaatctctt cagtgtaatg tgtttgggac ttgctaggct agaaaaatgg   1440
 gttccactga tgtataaaca tacattcgac accttcaaga ggtgtacaga catagtgttt   1500
 cccagactca cttgaccttt ccagggaaca cctggaataa tcactggctc ttgggacagt   1560
 catttcctag ggaacacaat tagaggaatg ccaagttaaa gcagattttc taaagtagtg   1620
 gttcacatat tgtagtaagc atcagaaaca cagatgccac accccttcag aagtccaggg   1680
 tgggacctgg gaacctgcat ttctgagacc gccccttccc ccaccccccc acaagtgaag   1740
 ctgatgctgc tgcaccgaag accgcccttg gagtggcact tgttgagagg atggcctgca   1800
 tagatctcag ctgcaggaag ccctcctatg gcctcaggaa aggctgcaca tggcatttgc   1860
 acaaccaatg agtcggaggt caaatcagcc cagtgacttc tcagagggtc catgcaacct   1920
 tggcactgac acttgaactc ctggctctgt acccctgcct cacttaggtg acccaggagg   1980
 agtgactgca tcttaacaag aggacttaac agtagcccct tgcacccccc agtggatctt   2040
 gtgatgttta agataaatgt ttgctaaaaa atgcactaac tagcctaaag catcatacaa   2100
 gtgtctgtta atcagaagaa tgtgccagcc acagcaggaa aatcccagat gaattttctg   2160
 tcttgttacc tctgagcctt gacgaaggca tattctgaca actaacgaag agaaaagagg   2220
 ctaaaaatgc agacaactgc agtgaggggg aaatacatga gtggattatc taattaaaaa   2280
 tgcctgattg ttaaaaaaac aaaggtcagc ccacaatcaa agtagttaat tatgctggct   2340
 ttgagatagt gtttaaaagt taaatatgtt gatctttgaa cacactcact cctccactct   2400
 accatgttaa tgctggttaa aatttaacac tagaaaaatg agaaaaaaaa tcctccactc   2460
 aaatacatat gaattacacc taaaatattt ggctgagatc gttccaatct tataagctac   2520
 gattgtgtgg aaatttcata agcaattttg aaaaaaagac atcaaatttt ggctcataga   2580
 aacatccaca gaatgaggaa taaacccacc attcacatgt ttgcatgtgt gtttagttaa   2640
 tggcccagta ccactttggc taatgaactg cctctcacaa ttacaaaaac gaacctgtaa   2700
 aaattcatac atatccgtga tgagattaca gtcaaacatc atgttgccaa gtcctggttt   2760
 ccaccgtgaa cccaaaagat tgatcagaaa ggcagaactt cccccaacac gttgcatgat   2820
 tcactttatg tatgctctgg atggctctga agacaagaca acatctcttg aactggtctg   2880
 ctttcgtagc agatctgata cactgcagta aacaatggaa acttgtccag tagtcccttc   2940
 tgtttgagga tgcggtacac ttcagcagaa gtctgcggtc cttggagctt ttgcccattc   3000
 agcatctcct tctccaactc ttcaatggtc ttcccagttc tggcgaaggc ctcggccacc   3060
 ctgcggttcc gccctccgta acaggtggtg atcaggtcgg ccaccccgca gctctctagg   3120
 aaggtggctg tagacacttg gcctttgcag aagatcctgg caaaagcaat catttccatg   3180
 agtcccaggc ggatgacggc cgctttggtg ttgtctccac agcggaggcc gtcgcagaac   3240
 ccagctccca cagctacgat gttcttaagc gcaccacaga gttcaacagt gtctgcatca   3300
 tcaaccacgg taattcgaaa atttggagtc tgcagaagtt ctttgaagag aaggccgttc   3360
 tccattactt tgctgccgat ggtggtctca cagaacttct ctgcagccac ctcattggca   3420
 atgttggctc ccatcagcac actgatgtca atacccatct tctcacggat gatgtcagaa   3480
 atgagcttca gcccctcggg gccctcgtct atgcccttga tgagggtgat tcccagcgct   3540
 ttcttgggca ctctcccagt gatctcatca cagattctgt gaatgaactg gtggggaatg   3600
 acaaacacca gcaggtctgc atcctgcaca gcctcgctaa gatttgacat ggcaaccaca   3660
 ttttctggca gcttgtgtcc aggaagatat tttacatttt catggtcatt atttatgatg   3720
 tctgtcagtt ttctgccatt cactgtttct tcaaagaccc acatcttgac tgtggaggca   3780
 aatttctgaa gtttcttgac gttattacca attatttttg caacagctga accccagttc   3840
 cccgagccca cgatgcacac tttcaggggc gccgctgcca tggccgggcc gaatgtagcc   3900
 gcctggaccg tgcttccctg gccggctgcc cacctccgcc tgttcagcct tgcccgcagc   3960
 ggctggcggc ggccccgccc ctttcgcctc tccgccaatg gtcgcggcca cccccgcccg   4020
 gcgccggggg ccgcagctga cagcggggca ggacccgctt c                       4061



      <210> 2383
      <211> 2141
      <212> DNA
      <213> Homo sapiens


      <400> 2383
 aagaaccaca gtgtcagaaa tgaaagagta caacttcaca gaatgtgttg tctctgacag     60
 gttgatagcc acttaccttc tccatctttt cttcctcaag gatagcagct gcttcccaca    120
 gatacaccaa caggcaattc cagcccctct ctaccacact taccatttgc aggtgcctgt    180
 ggcttgtcta tttacaacct tgtccctaca cagcagaagc ggaacccttc aggaagttct    240
 ggattcatcc tcagcaggat ctgtttcaca aactattctc cagtcccacc ttccctccag    300
 atgttcttcc ggcttcaatt gccacctgtg aatagtgaag aaacttctca ctatgagatt    360
 ccattgcccg gaaggagggt agagctacgg tacccactaa ggcagggaac agaagcaaca    420
 gacggacagg tctgtggaaa tgaggatatg ctaataaggg accgagtcag gaaaactaga    480
 gggtcagcac cgcccccagc ccacaacctg gcacccacgg aagttgcttt agaggacgtc    540
 ctgcgtatct tcacctctgc gtggcgtggg gtcgacggcg ctctggagaa gggaggaact    600
 tcctgtcccg cgcgcgcaca acttccggca gagccggaag accctctctt tcgctgtttg    660
 agagtctctc ggctcaagga ccgggaggta agaggtttgg gactgccccg gcaactccag    720
 ggtgtctggt ccacgaccta tcctaggcgc catgctatag cagagcatgc agggtcacca    780
 aagccactca ggaagaggga accagaaacc tggcaagcta acaaaaaggg tgtgataggt    840
 atacagctgg ttgttaccat ggtgatggcc agtgtcatgc agaagattat acctcactat    900
 tctcttgctc gatggctact ctgtaatggc aggaaatata atggtcacat tgaaagtaag    960
 ccattaacca ttccaaagga tattgacctt catctagaaa caaagtcagt tacagaagtg   1020
 gatactttag cattgcatta ctttccagaa taccagtggc tggtggattt cacagtggct   1080
 gctacagttg tgtatctagt aactgaagtc tactacaatt ttatgaagcc tacacaggaa   1140
 atgaatatca gcttagtctg caaagttcta ttttcattaa ctacacacta ttttaaagta   1200
 gaagatggtg gtgaaagatc tgtttgtgtc acctttggat tttttttctt tgtcaaagca   1260
 atggcagtgt tgattgtaac agaaaattat ctggaatttg gacttgaaac agggtttaca   1320
 aatttttcag acagtgcgat gcagtttctt gaaaagcaag gtttagaatc tcaaacttta   1380
 cttcatatca acttcttggc acctttattt atggttctgc tctgggtaaa accaatcacc   1440
 aaagactaca ttatgaaccc accactgggc aaagaaagta tccctttaat gacagaagcc   1500
 acattcgata ctctgcgact ctggttaata atcctgctgt gtgctttgcg gttggccatg   1560
 atgcgtagtc acctgcaagc ttatttaaat ttagcccaaa aatgtgtgga tcagatgaag   1620
 aaagaagcgg ggcgaataag cacggttgag ctacagaaaa tggtggctcg agtcttttat   1680
 tatctttgtg tcattgcact gcagtatgtg gcgcctctgg taatgctgct tcacacaact   1740
 ctgcttttga aaacactagg taatcattcc tgggggtatt tatccagaat ctatctctac   1800
 cttaccagtg gataatagtc tactgtccaa ttctgtttac tctgaattac catcagctga   1860
 agggaaaatg aaggtaactg ttacacaaat aacagtggca ctgagcagct taaaaaatat   1920
 ttttactcct cttctttttc gaggacttct gtcttttctg acctggtggt attgctgctt   1980
 gcctcttttc tatcaagcct ttttgggctt ttctatcacc agtatctgac tgtggcatga   2040
 atctcagtta acaaaaaagt catatccaaa tcacccttta aattaaaata tctgtgccct   2100
 taaagggctg atgaaaacca gaagaaagca aatacaatgg g                       2141



      <210> 2384
      <211> 1076
      <212> DNA
      <213> Homo sapiens


      <400> 2384
 ccacagctac agccacagcc acggccactg tggcagccct gcaggagaca cagaacaagg     60
 atataaacca gtatggccgg tctgttctct ctttccagat gggtcccacc caggcgtata    120
 acagccaatt catgaaccag cccgggccgc gggggcctgc ctccatgggg ggcagcatga    180
 accccgcgag catggcggct ggcatgacgc cctcggggat gagcggccct cccatgggca    240
 tgaaccagcc ccggccgccc ggcatcagcc cctttggcac acacgggcag cggatgcccc    300
 agcagaccta cccgggcccc cggccccagt cccttcctat tcagaacata aagaggccat    360
 accctggaga ggcatttgtg cccagcagag cagggaccaa ccgtgggtgt gaccagaagt    420
 ttccacttgg caccatctct gccacccttc ccatcatcct gactctcccc ctctttgcct    480
 ccacggacca ctacttcctg cacgcgggcc attctgaccc cctcttcatg acagaaactt    540
 ttgtatcctc cttcaaggcc ttgttgtcct cctggtgcga agagctcggc cgcctgctgc    600
 tgctccgaca tcagaagagc cgccagagcg atccccctgg gaaactcccc atgcagcccc    660
 ctctcagctc catgagctcc atgaaaccca ctctgtcgca cagaaatcag acctgcttcc    720
 agcaccagaa gccatgtgac ctgggtctgt gtcttcccgt ttcctcctct attaatgggc    780
 atgctgataa gagcgccagt tgcctttccc acggcactga aacagaggga gaagctgggg    840
 agaaaggatt aacaaaagag ttagatgaca tcactgattc cagaagccta aattcagtaa    900
 ctcttggggt catcgggcct ggctgggact cctcgctact ccttagacag cctcgaaacc    960
 tcctgaacca gagctctctc gagaagcagg ccctctcggg ggtctgcagt cacccagtcg   1020
 atactcctgg cccccacctt ctcctggagg tgggcaagaa ggagggtctg gactga       1076



      <210> 2385
      <211> 523
      <212> DNA
      <213> Homo sapiens


      <400> 2385
 atgctctgcc gcctgggcgc ccaagctgca gttgctctct gtgtgcaggc agcagctgcc     60
 tggcaacccc cgagcccgct cgcactccca ccatcgcaga accagggcca ggtgtcccag    120
 tggctgcggc caagccaggc attctgccgg atcatggcac aagttgcagt ttccactctg    180
 cccatggaag atgaggagtc cattgaagat gaggagtctg ttgaagatga ttccgtcgga    240
 gagcaggatg gtggtgacat ttctcatatc agctctcgag tccacggaac aataccacgg    300
 gggcgtgtac accccctgcg atattgacag taatatcatc ctctcccccc cagatattag    360
 taacaatatc accgaaggtg tctacacccc ctgtgatatt gacagacacc tgattccctt    420
 cttcctgccc ttggacatga gactccaggt tcttatgcct ttggactctg ggacttgcac    480
 cagcggcttc cccgaggctc tcaggccctc ggcctcagac tga                      523



      <210> 2386
      <211> 1256
      <212> DNA
      <213> Homo sapiens


      <400> 2386
 ctcgatcacc tgatggccct gcggcgcagc tcccgggttg acccacgcgt ccgagcggat     60
 gttcactctc acgaccatga ttcaagctct tgcacctgtt atgggatggg acaggaagcc    120
 actgaagatg ttttcatcag aagagatgag aggacatctt catcatcatc ataaatgtct    180
 gacgaagatc ctgaaggttg aggggcaggt tccagatctg ccatcctgcc tgcccctgac    240
 tgacaacacc cgcatgctgg cctctatcct catcaacatg ctctatgatg acctgcgctg    300
 tgacccggag cgcgatcact tccgcaagat ctgtgaggaa tatatcacgg gcaagtttga    360
 cccccaggac atggacaaga acttgaatgc catccagaca gtgtcaggga tcctgcaggg    420
 cccctttgac ctgggcaacc agctgctggg actgaaaggt gtgatggaga tgatggtggc    480
 actatgtggc tcagagcgcg agacggacca gctggtggcc gtggaggccc tcatccatgc    540
 ctccacgaag ctcagccgcg ccaccttcat catcaccaat ggagtgtcac tgctcaaaca    600
 gatctacaag accaccaaaa atgagaagat caagatccgc acactggtgg gactctgtaa    660
 gctcggctct gcaggtggca cagactacgg tctcaggcag tttgcggaag ggtcgacaga    720
 aaaactggcc aaacagtgtc gcaagtggct gtgcaatatg tccatagaca ctcggacccg    780
 acgctgggca gtggagggcc tggcctacct cacgctggac gctgatgtga aggacgactt    840
 tgtccaggac gtccctgccc tgcaggccat gtttgagctg gccaagacca gtgacaagac    900
 catcctgtac tcggtggcca ccaccctggt gaactgcacc aacagctacg atgtcaagga    960
 ggtcatccca gagcttgtcc agctcgccaa gttctccaag cagcatgtgc ccgaggaaca   1020
 ccccaaggac aagaaggact ttatagacat gcgggtgaag cggcttctga aggcgggtgt   1080
 catctctgcc ctggcttgca tggtgaaagc agatagtgcc atcctcactg accagaccaa   1140
 ggagctgctg gccagggtat tcctggcact gtgtgacaac ccaaaggacc gaggcaccat   1200
 tgtggctcaa ggtggtggca aggccctgat tcccctggct ttggagggca cagatg       1256



      <210> 2387
      <211> 1911
      <212> DNA
      <213> Homo sapiens


      <400> 2387
 cccttctcgg ctgtgtggct tcgacttcct gattctccca cgacgtccct ggccgggaga     60
 cccgctggac tctgcggctg gccaaaaggg gagggggagc cccgcgtcct gggggcccct    120
 agcggaaggg gcgggggttg cgctgggcat cctgtctggg gcatctgtct gggactctgt    180
 tggtgcctct cacctggcga ggggcctgtg gtgggggtag gggggaagtc cctggcgcca    240
 tgcttggcca agccctgctc tgctgggctg cgggctggcg gcgctcaccc agctcctcac    300
 ctgtcccgca tcttcctgtt tttcttccct ttctggttgg gcagcgagag ttgagaggag    360
 gcagatggct tccatcccag aaatcgctct cctctttcca tccctacaga gagggacaga    420
 gaggcaaagt tccttgcatc ccccggggca ctgtccctgt gagctcccgg tgtcctgcac    480
 atgtgagccc ctgagtcacc gggcctgtga gtgtgggatg gggctccgtg gccagcctgg    540
 cctcctgggg ttcactttgt gctttcctac gccaactctt cctgtgtggc tttgctggcc    600
 ttccactgag gaggcacata ggtttggagg acagatgagg gcccactgga gagctgtacc    660
 cctcagtgag ggccgccacc ttgatggttt ttgatggata atggggttga cctctttgtt    720
 ccttccacat gtttttatgt ttgaccattt gctcagctga gcttgtctta ataattggat    780
 tcatggttaa tgagccccac atgggcgaga gggtggcctt cattctgaac ccatttaggc    840
 agcacgggca gccctcctcg ccatgggcag gatcagagcc cccccgccca gtcttggggt    900
 tgctcctgga tgctgtctgg gaggcttgct catggtgaca tcctcatctc cccgtgcacg    960
 ttaccgcatt cagagcttgg gtcacctgga cactgaactc aggtgaattt tctctgagat   1020
 cccgggagaa ggaggacagt tctttggaag gttttccagg gccgatcacg gaaaggatga   1080
 gaagggagag gtcctggtgg gggacacaat tacagtggca gtgtaacacc cggaaacttt   1140
 attgcgtgaa gtccctctca ctccctctac ctccttcttt tacgtggact ctgccaaaga   1200
 ccaggatacc agaatgccag tggagtgacc aagtgtagtg ggaccttggg aacgcgagtc   1260
 tggagccagg cggctggggt ttgcatcctg gttctgcccc tccttagctg gctgacatgg   1320
 cacaagccac ttaccctctc tgagccttac tgtcttcagt ggcaaatgga tctgtcaaca   1380
 ggccccattg cctggggttg ttactgctga gattaaggga tgctcgtcca taaaaagact   1440
 tagcgttgtg cctggcacat agtgtatggt ggataaatgg gacttaggac taaaactcat   1500
 gccttggtgt gtttttgcag tgatgttttg ttctggggtg catcacaaga gacaaggttc   1560
 ttggctgggc atggtggctc aggccaataa tcccagcact ttgagaggcc gaaaggggag   1620
 gatcgcttga gcccaggagt ttaggaccgg cctgggcacg gtggtgaagc ctcatatcaa   1680
 ccaaaaataa aaaaataaaa aataaagcca ggtatggtgg tgtgtgcctg tggtcccagg   1740
 tgctttggag gctgaggtgg gaggattgct ggagtctgga gggtcgggct gcagtgagct   1800
 gtggtcgtgc cactgcactc cagcctgggt gacaaagtga gactctgttt caaggaaaag   1860
 agagagagag agacagacag atccacaaga gtcttaagcc agaatcttca t            1911



      <210> 2388
      <211> 651
      <212> DNA
      <213> Homo sapiens


      <400> 2388
 gcaccgcgtc cggaattccc gggtttgaga agtgaaacca gccatgtata tgctgctcca     60
 agcattttgg ttgtggcagg aaactttgaa gactattttg ctgtacaaat tcacaaagcc    120
 ccctgcaaac actcccgtgc ttggggtgaa tgcccaagtg tgtcacagct gccttgcagc    180
 tctgaggatc agaaaggtta atggacataa aagaaacttc aaagctcaac ctcctaatgg    240
 gaagctgccc ttggttttag gctgtctttg cttactgacc gacttaattc atgctttggg    300
 ttatgactgt aggagagatt ttcctgtgtc tttggagtat gctgaacttg tgtttctttt    360
 tgttgttgca tattagacag tcagtgttga aactaaagtg acctaaagtg actgagctca    420
 tgttatgggc tgaattttgt ctccccagaa ttcataggtt gaagccttcc cagtccttag    480
 aacatgattg tatctggagc tatggccttt aaagacataa ataaggtaac atgaggtcat    540
 aagggcaagg ccctaatcca atatgactgg tgtccttata cgaagaggaa gaggccaggc    600
 gtggtggctt acgcctataa tcccagcact ttgggaggcc agggccggca g             651



      <210> 2389
      <211> 693
      <212> DNA
      <213> Homo sapiens


      <400> 2389
 tcagcaacgg aaaacaggtt tgctctcggg tcctgatgct gactgatgag cactggattc     60
 ctggagcact ggcttcagaa tgatgttgag gccaagtcct agctcagcag aaaggacggc    120
 tgtgattagc gatgtggccg attgggcctg tctgccatgt agcttgcctt ctatattcct    180
 gtccaatgat ggttcttcgg cgccaggtga ttttccatca ctctgtgcca taggaggctg    240
 ttccccgact ggggccttta tgcatacggc tgtgcagccc cagtgggctc tggatgccag    300
 ctggccaggg ctggctgcca gcacaagcac tggggctcca ggctccgcat tcatgcctgt    360
 ggtgaccacc tcacagggcg atggccaccc cagctgcttc tccctggccc tccgcaagcc    420
 cttgcctcct gctgcaccct ctccctccag catcccctgg gccttgctct taacagcagc    480
 agaagcctgg gtgtcctggg ggttgggaca gagagaaata acttgacttc ttccttgtgt    540
 ttcttcagca atttctgcca agaccctcat cttcagaaat ctagatgctg ccaggcttcc    600
 cagcagcggc ttatggacca gtggcagcag cggcggtggc ggcagcaaga ggatcaggta    660
 ggaaggtgta tgggacaggc gactcccagg cat                                 693



      <210> 2390
      <211> 534
      <212> DNA
      <213> Homo sapiens


      <400> 2390
 gccataccaa ggttattgtc ctagttagga atgtgggacc cttacactgg gatggggaca     60
 tctggatcga tactctagaa ctctagaaaa cctggacacc ccagccccgc caccctcccc    120
 cacaccctga aacctctaag cccactcctc cctgttaagg gccggtgctt tgctcttgtt    180
 tgaaggtcat gcccaggcct ctgccacctc cccttaggat ctgtgctcac cacccctcct    240
 ggcccctgga ccaagaaggt cagcaggagg gtgctgggcc tgccagagaa gaaagaagat    300
 gagctgcctg gggggagcag gagtgtgcct gaaacaaggg catggccata tggggctctg    360
 ctatgaccta ggactcagca cccttgcaga gcccccagga agcagtgccc gtaggctgcc    420
 agctcggtcg gctctctgaa acttcccagg aagccatggc ccacaaggaa gagaatagca    480
 acctaggggc aaccgtggca gctctgcaag aagcgaaggg aatagagtac ccta          534



      <210> 2391
      <211> 891
      <212> DNA
      <213> Homo sapiens


      <400> 2391
 atggcggaaa cagcggttat caatcacaag aaacgtaaaa atagcccgcg aatcgtccag     60
 tcaaacgacc tcactgaggc ggcatatagt ctctcccggg atcaaaaacg tatgctgtat    120
 ctgttcgttg accagatcag aaaatctgat ggcaccctac aggaacatga cggtatctgc    180
 gagatccatg ttgctaaata tgctgaaata ttcggattga cctctgcgga agccagtaag    240
 gatatacggc aggcattgaa gagtttcgcg gggaaggaag tggtttttta tcgccctgaa    300
 aaggatgccg gcgatgaaaa aggctatgaa tcttttccct tggtttatca aacattccac    360
 aaacatcaca tcactctctt tgtggttttt ctcatcctgt acacattaac tgtggctggc    420
 aatgccatca tcatgaccat catctgcatt gaccgtcacc tccacactcc catgtacttc    480
 ttcctgagca tgctggctag ctcaaagaca gtgtacacac tgttcatcat tccacagatg    540
 ctctccagct tcgtaaccca gacccagcca atctccctag ccggttgtac cacccaaacg    600
 ttcttctttg ttaccttggc catcaacaat tgcttcttgc tcacagtgat gggctatgac    660
 cactatatgg ccatctgcaa tcccttgaga tacagggtca ttacgagcaa gaagtcatat    720
 acctttgacc tccctacttg tctgagcaat ggcttccacg aggctagtga ggacagaaac    780
 ccaaacagta gcttgtccat gttcttagct tgggctctta cagcagcagc agtgaccggg    840
 atgagggtat cagatagcac aatggttgtg cccacccagc ttctaactta g             891



      <210> 2392
      <211> 897
      <212> DNA
      <213> Homo sapiens


      <400> 2392
 atgcctggcc ccatgtccct ctggctcctc ctgctggttc tgccactgtc cctggagcac     60
 agtgatctca gaatttgctt ccccgggcag gtggtcagca tggaaagcag ctccacgggc    120
 ttcatctgga ctgatgtcag agcctggcag acatcaaatc ggcatgtttc ttcttggagg    180
 gaacccaggc attctcggat gccccctggg gccggcctca tggagcggat ccaggctatt    240
 gcccagaacg tctccgacat cgctgtgaag gtggaccaga tcctgcgcca cagtctgctc    300
 ctgcacagca aggtgtcaga aggccggcgg gaccagtgtg aggcacccag tgaccccaag    360
 ttccctgact gctcagggaa ggtggagtgg atgcgtgccc gctggacctc tgacccctgc    420
 tacgccttct ttggggtgga cggcaccgag tgctccttcc tcatctacct cagtgaggtc    480
 gagtggttct gccccccgct gccctggagg aaccagacgg ctgcccagag ggcacccaag    540
 cccctcccca aagtccaggc agttttccga agcaacctgt cccaccttct ggacctgatg    600
 ggcagcggga aggagtccct gatcttcatg aagaagcgga ccaagaggct cacagcccag    660
 tgggcgctgg ctgcccagcg cctggcacag aagctggggg ccacccagag ggaccagaag    720
 cagatcctgg tccacatcgg cttcctgacg gaggagtccg gggacgtgtt cagccctcgg    780
 gtcctgaagg gcgggcccct aggggagatg gtgcagtggg cggacattct gactgcactc    840
 tatgtcctgg gccatggcct gcgggtcaca gtctccctga aggagctgca gagatag       897



      <210> 2393
      <211> 1841
      <212> DNA
      <213> Homo sapiens


      <400> 2393
 aaccaatgac aaaaaccaca tgattacctc agtagatgga gaaaaggcct ttgacaaaat     60
 tcaacagccc ttcatgctaa aaactctcaa taaactagtg ttggaagttc tggccagggc    120
 aatcaggcaa gagaaaggaa taaagggtat tcaattagga aaagaggaag tcaaattgtc    180
 cctgtttgca gatgacatga ttgtatattt agaaaacccc atcgtctcag cccaaaatct    240
 ccttaagctg ataagcaact tcaacaaagt ctcaggatac aaaatcaatg tgcaaaaatc    300
 tcaagcattc gtatacacca ataacagaca aacagagagc caaatcatga gtgaactccc    360
 attcacaatt gcttcaaaga gaataaaata cctaggaatc caacttacaa gggacgtgaa    420
 ggacttcttt aaggagaact acaaaccact gctcaacgaa ataaaagagg acacaaacaa    480
 atggaagaaa attccatgct catgggtagg aagaatcaat attgtgaaaa tggccatact    540
 gcccaaggta atttatagat tcaatgccat ccccatcaag ctaccaatga ctttcttcac    600
 aaaattggaa aaaactactt taaagttcat atggaaccaa aaaagagccc acattgccaa    660
 gacaatccta agccaaaaga acaaagctgg aagcatcgcg ctacctgact tcaaactata    720
 ctggaaggcc acagtaacca aaacagcgtg gtattggtac caaaacagag atatagatca    780
 atggaacaga atagagccct cagaaataat accacatatc tacaaccatc tgatctttga    840
 caaacctgac aaaaacaaga aatggggaaa ggattcccta tttaataaat ggtgctggga    900
 aaactggcta gccatatgta gaaagctgaa actggatccc ttccttacac cttatacaaa    960
 aattaattca agatggatta aagacttaaa tgttagacct aaaaccataa aaaccctaga   1020
 agaaaaccta ggtaatacta ttcaggccat gggcatgggc aaggacttca tgactgaaac   1080
 accaaaagca atggcaacaa aagccaaaat tgacaaatgg gatctaatta aactaaagag   1140
 cttctgcaca gcaaaagaaa ctaccatcag agtgaacagg caacctacag aatgggagaa   1200
 aatttttaca atctacccat ctgacaaagg gctaatatcc agaatctaca atgaactcaa   1260
 acaaattaac aagaaaaaat caaacaatcc catcaataag tgggcaaagg atatgaacag   1320
 acgcttctca aaagaagaca tttatgcagc caacagacac atgaaaaaat gctcatcatc   1380
 actggccatc agagaaatgc aaatcaaaac cacaatgaga taccatctca caccagttag   1440
 aatggcgatc attaaaaagt caggaaacaa caggtgctgg agagcatgtg gagaaatagg   1500
 aacggttgga tataaaaacg atagacaaga aacacaacga acaaggaaat tacataatat   1560
 cttagaggat aagccctatg gggaaataaa tcaaattttc cttcaagttg gacagcggaa   1620
 gaatggatat gcaagacctc aaaaaagttg ccttccatgt aacattttcc agtatgtgtt   1680
 ccagaaaaaa atgaaagaga aaaccaagaa agagaaaaaa tggaatctag gaaacacaag   1740
 aattaagcca gagaaaggca aagaaaacat gggaggaaca gttcttcccc cttcctctcc   1800
 catcatctgg gttgaatatg agccaccagt atcatccccc a                       1841



      <210> 2394
      <211> 493
      <212> DNA
      <213> Homo sapiens


      <400> 2394
 cggtcggatt tcccgggccg acgatttcgt ctgcagggga gtgagggaga ggaggatagg     60
 aagcaggaaa gcgggagagc tcgagggaca agggggctcg gtgtgtttac accaggcacg    120
 ggctacgagc gtccatcccg gcccctggct tgcgctcccg aagaggagag caaggctgtt    180
 ctgggatccg gccgtcgtgc ggcaagaggc ttgtctgtcc gggttgccgg aaccaggaga    240
 acccagaggg aaaccgaggg aaaggagcgg cgcgttttac tagagagagc gcgagcggaa    300
 gaggcgagag caggagcgcg cgagggagca tcgagcgcag cggagacatg aggacctact    360
 ggctgcacag cgtctgggtg ctgggctttt tcctgtccct cttctcattg caaggactgc    420
 ctgttcgcag cgtggatttt aaccgaggca cggacaacat caccgtgagg cagggggaca    480
 cagccatcct cag                                                       493



      <210> 2395
      <211> 395
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(395)
      <223> n = a,t,c or g


      <400> 2395
 ccagcccggg cttcctgccc tgtggccgca ggtgggtgga aggcagagcc tggggtggat     60
 gagtctgtcg cccacccagg ccaagccagg ctgttcttgg ggtggaggct gcgggcctgc    120
 tcccttaccc ctctgctgcc cgcctaactg cccctcagga cctccctggc ccacccgcct    180
 cccagctcca tctcctgctg gcagctcctg cctgggggca gacacctccc tccctcctgg    240
 gctccctcag tctggctgca ggtggcactg tcgggcccca caatggcctc tgccctgtcc    300
 cttggagtgg gacccangag tctggtgggt gatggagctg gcgagcccgt cccaggcaag    360
 cagcttgaag gccatggggt aacgccctgc ccccc                               395



      <210> 2396
      <211> 739
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(739)
      <223> n = a,t,c or g


      <400> 2396
 cgcccggctt actcccttgc tggctcatcc cactgaagag ctatggcact tccaattcct     60
 gagcctttgt gaggttctgc gtgtcagtaa gcttgcttcc gggcatcacc tccgaaaaca    120
 cttgggtttc agttttctct gtgaggcttc ttaaggagtg gaggaaagtg gatgttttca    180
 agataacgca gctaacattc aaagaggtta agtgaattgt ccaaagtcac acagcaagca    240
 ctggaggatt agaaaagcac ttgggaagcc cattaatctt gccggcgttg tcaggagtga    300
 tcagcgagtt ttattaaaag ccctgggatt gcctgaaagg cccccttgtc tgactttgaa    360
 atgaaagggg catgttaaca tctcggggca cattgtcagg acccctcacc ctgccccttg    420
 gactatgagc tgaccctcca ggaggaagca cagaagccct cctttgttaa agggatttcg    480
 ccggtggaca gagaagagtt gggccctgtc agcatgaact ctctgagttg gggggctgcg    540
 aatgccgtgc tgctgctgct cctcctggcc tgggccagcc ccaccttcat cagcatcaac    600
 cgcggggtga gggtgatgaa gggcccctct gccttcctgt caggagatga catgaagttt    660
 gccatcccta aagagaaaga tgcctgctgt atacgagaat cgtcgacccg aatnnnccgg    720
 agcggttccg cagggttac                                                 739



      <210> 2397
      <211> 427
      <212> DNA
      <213> Homo sapiens


      <400> 2397
 tcatgtcatc aaagtgcttc atgatgactg gattttcaca ccatttatcc aagggcccta     60
 gtcaatggca gcagcaagaa tgaaagtaga cacattggaa gctagagagt cactgggtga    120
 cttttggagg tgttgaaaag tctcctctag agctttggaa ggctgaatgc actaaacatg    180
 aagagcttga aagcgaagtt caggaagagt gacgtaaatt aaataaaact catagagtgc    240
 aaagagactt cgacaaagac agaaaactag ctgttggcca gagtgaaagt cctggtcatc    300
 cgacttccga gaaacctcct tcaacctcat cgtctgctgg ctgtatgtta tgcagcctac    360
 atatctcccg tggctttcag ctaaggagaa aaaggcaatt aaatggaaaa tgttgcccaa    420
 ttcaaaa                                                              427



      <210> 2398
      <211> 409
      <212> DNA
      <213> Homo sapiens


      <400> 2398
 ggaggcagga gggtgaggac agtgcaggtt cttggcacag ccagggtcca ggacagtgtc     60
 agggcagggc caaggcaggg tctgggcctt gataagacca gcaacagggc tggggctagg    120
 ccagtgacag gaccagagtc agggcaaggg ccagagcagt gcaaggccag ggtagggcca    180
 ggcatttcag ggtcagggcc aggggagaac cagggcaagg tctgaagcag ggaagggcca    240
 gggccaggac aggtccaggg cagggccatg acacggccag gggctgcgtt agggcaaggg    300
 cagggccaga gcaaggtaag ggtcagggcc aaggccaggg tagggacagg gcaagaaata    360
 tggcaggacc aggggcaatg ccaaggccaa ggctgggcca gggctgacg                409



      <210> 2399
      <211> 448
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(448)
      <223> n = a,t,c or g


      <400> 2399
 tctgacgcct ctgaacncct tcggaatctc cggtcgacct acgcgtgcgc ctcactggaa     60
 gcacgacacc tgattggaca acagcacctt ggacgaccct agctccgtta catatacttg    120
 gattgcagct ggggcctaga tttgctgagg acggaggcca aggagacagg aacatgtggc    180
 tgctcccagc tctactcctt ctctgcctct caggctgttt gtctctgaag ggccccggct    240
 ctgtgactgg cactgcgggg gactctctga cagtgtggtg tcagtatgag agcatgtaca    300
 agggatataa caagtactgg tgccgaggac agtacgacac gtcatgtgag agcattgtgg    360
 agaccacagg agaagaaaaa ggtggaaagg aatggccgcg tgtccatcag agaccacccg    420
 gaggctctcg ccttcactgt gaccatgn                                       448



      <210> 2400
      <211> 3680
      <212> DNA
      <213> Homo sapiens


      <400> 2400
 attgacctgc tgcggcagta gaacgagctg aagtcacccc acagccctat ttccttcttt     60
 cctgttcctc accccgatca cgcttgattt attgatggtg gttccaccag gcctaatcgc    120
 cacacaccag caaaggcagg ctatgctata gtacaagcca ctagcctgcc tctcagaacc    180
 tctcatttcc tttccatcgt ggaaatctat cctcaaggaa ataatttctc agtgttccat    240
 ctgctgttct actattcctc agggattatt caggccccct cccttcctta cacatcaagc    300
 tcgaggattt gcccccaccc aggactggca aattagcttt attcaacatg tcccaagtca    360
 ggaaactaaa atacctctta gtctaggtag gtactttcac tggataggta gaggcctttc    420
 ctgcagggtc tgagaaggcc accgcagtca tttcttccat tctgtcagac ataattcctc    480
 agtttagcct tcccacctca atacagtctg ataacaggtg agcctttatt agtcaaatca    540
 gccaagcagt ttttcaggct cttagtattc tgtgaaacct ttatatccct taaggtcctc    600
 catcttcaag aaaagtagaa tggactaaag gtcttttaaa aatacacctc accaagctca    660
 gccaccaact taaaaaggac tggacaatac ttttaccact ttcccttctc agaattcagg    720
 cctgtcctcg gaatgctaca gggtacagcc catttaagct cctgtataga tgctcctttt    780
 tattaggccc cagtctcatt ccagacacca gaccaactta gactgtgccc caaaaaactt    840
 gtcatcccta ctatcttctg tctagtcata ctcctattca ccattctcaa ctactcatac    900
 atgccctgct cttgtttaca ctgccggttt acactgtttc tccaagccat cacagctgat    960
 atctcctggt gctatcccca aactgccact cttaactctt gaagtaaata aataatcttt   1020
 cctggcagga ctatggtgaa tctccttaag cactctctaa tcagacatcc tgagtcgtcc   1080
 caattcttag accttttata cctgtttttc tccttctgtt attccattta gtttttcaat   1140
 tcatacaaaa ccgtatccag gccatcacca atcattctat atgacaaatg tttcttctaa   1200
 caaccccaca atatcacccc ttaccacaag acctcccttc agcttaatct ctcccgctct   1260
 aggttcccac gccgccccta atcccgcttg aagcagccct gagaaacatc gcccattctc   1320
 tctccatacc accccccaaa aatttcaccg ccccaacact tcaacactat tttgttttat   1380
 ttttcttatt aatattaagg aaggcaggaa tgtcaggcct ctgagcccaa agccaagcca   1440
 tcggcattcc ctgtgacttg cacgtatacg tccaggatgg gcctgaagta actgaagaat   1500
 cacaaaagaa gtgaatatgc cctgccccac cttaaagaag tgtaaatggc cggtccttgc   1560
 cttaactgat gacattcccc cacaaaagaa gtgaaaatgg ccggtccttg ccttaagtga   1620
 tgacattacc ttgtgaaagt ccttttcctg gctcatcctg gctcaaaaag ctcccctact   1680
 gagcacctta tgacccccac tcctgcccac tgagcacctt gtgaccccca ctcctacccg   1740
 ccagagaaca aacacccttt tgactgtaat tttcctttac ctacccaaat cctataaaat   1800
 ggccccaccc ctatctccct tcgctgactc tcttttcgga ctcagcccgc ctgcacccag   1860
 gtgaaataaa cagccatgtt gctcacacaa agcctgtttg gtggtctctt cacacggacg   1920
 cgcatgaaat ttggtgccgt gactcggatc gggggacctc ccttgggaga tcaatcccct   1980
 gtcctcctgc tctttgctcc gtgagaaaga tccacctacg acctcaggtc ctcagaccaa   2040
 ccagcccaag aaacatctca ccaattttaa atcagcggcc aggcgttcct ccagaacctc   2100
 ctcccacagg aacttgctac acatgccgga aatctggcca ctgggccaag gaacgcccgc   2160
 agcccgggat tcctcctaag ccgcgtccca tctgtgtggg accccactga aaatcggact   2220
 gttcaactca cctggcagcc actcccagag ctcctggaac tctggcccaa ggctctctga   2280
 ctgactcctt cccagatctt ctcggcttag cggctgaaga ctcacactgc ctgattgcct   2340
 cggaagcccc ctagaccatc acgcacgccg agcttcgggt aactctcaca atggaaggca   2400
 ggaatgtcag gcctctgagc ccaagccaag ccatcgcatc tcctgtgact tgcacgtata   2460
 cacccagatg gcctgaagta actgaagaat cacaaaagtg aaaaggccct gccccgcatt   2520
 aactgatgac attccaccat tgtgatttgt tcctgcccca ccttaactga gtgattaacc   2580
 ctgtgaattt ccttctcctg gctcagaagc tcccccacct taactgagtg attaaccctg   2640
 cgaatttcct tctcctggct cagaagctcc cccactgagc accttgtgac ccccgcccct   2700
 gcccaccaga gagcaacccc ctttgactac gcccatgaaa tttggtgcag tgactgggat   2760
 cgggggacct cccttgggag atcaatcccc tgtcctcctg ctctttgctc cgtgaaaaag   2820
 atctacctac gacctcaggt cctcagaccc accagcccaa ggaacatctc accaatttta   2880
 aatcagaagg caggaatgtc aggcctctgt gcccaagcca agccatcgca tcccctgtga   2940
 cttgcacgta tacgcccaga tggcctgaag taactgaaga atcagaaaag aagtgaaaat   3000
 gccctgccct gccttaactg aatgacattc caccacaaaa gaagtgaaaa tgggccggcc   3060
 cttgccttaa gtgatgacat taccttgtgg aaagtccttt tcctggctca tcctggctcg   3120
 aaaacaccgc cactgagcac cttgcgaccc ccactcctgc ccgccagaga acaactcccc   3180
 ctttaactgt aattttcctt tacctaccga aatcctataa aacggcccca cccctatctc   3240
 cctttgctga ctctcttttc ggactcagcc cgcctgcacc caggtgatta aaagctttat   3300
 tgctcacaca aagcctgttt ggtggtctct tcacacggac gcgcatgaaa tttggtgccg   3360
 tcactcggat cgggggacct cccttgggaa atcaatcccc gtcctcctgt tctttgctcc   3420
 atgagaaaga tccacctacg acctcaggtc ctcagacaga ccagcccaag aaacatctca   3480
 ccaatttcaa atccggtgca gctaccaggg gaactgccag gacttcaaag cccacaacca   3540
 aaagccagaa aacactacca agtacaagcc ccggacactg gacccagagc acaccctggg   3600
 catctgctct gagatcctct ccctggacag agacagctgc tccttcagaa acagaggaga   3660
 ccctgaacac aggcaggcct                                               3680



      <210> 2401
      <211> 4076
      <212> DNA
      <213> Homo sapiens


      <400> 2401
 gcttatggcg gcgctggaga gggggcgctg agctgttggg tatgaagtgt aacagaacag     60
 actttaccac ctgaaactgc tgcttcaagt tcagatcagg caaggaacaa acctcgtaac    120
 aactaacaag accaaagaag agtacactta agttgaagac acaacacttg atctgaaaca    180
 agaagtttgt gcctactcaa cagctttgaa agagcacttc ccaacgctgc tagtagtctt    240
 tgttttcttc agtgctgtac tgtgagattg cccggtacag cagcagttgt attctttatt    300
 agcttggtag atcattttct ctcgctcttt tttttaatac tagcaacttt catcctttga    360
 aacgtgtgct gaaaaagaag aatcagcaaa tactactgaa agtgcaatat ttgagtatca    420
 ctgcgagatg agctttgatc caaaccttct ccacaacaat ggacataatg ggtaccctaa    480
 tggtacttca gcagcactgc gtgaaactgg ggttattgaa aaactgttaa cctcttacgg    540
 atttattcag tgttcagaac gtcaagctag acttttcttc cactgttcac agtataatgg    600
 caacctgcaa gacttaaaag taggagatga tgttgaattt gaagtatcat cggaccgacg    660
 gactgggaaa cccattgctg ttaaactggt gaagataaaa caagaaatcc tccctgaaga    720
 acgaatgaat ggacaagttg tgtgcgctgt tcctcacaac ttagagagta aatctccagc    780
 tgccccgggt cagagtccaa cagggagtgt atgctacgaa cgtaatgggg aagtgtttta    840
 tctgacttac acccctgaag atgtcgaagg gaacgttcag ctggaaactg gagataaaat    900
 aaactttgta attgataaca ataaacatac tggtgctgta agtgctcgca acattatgct    960
 gttgaaaaag aaacaagccc gctgtcaggg agtagtttgt gccatgaagg aggcatttgg   1020
 ctttattgaa agaggtgatg ttgtaaaaga gatattcttt cactatagtg aatttaaggg   1080
 tgacttagaa accttacagc ctggcgatga tgtggaattc acaatcaagg acagaaatgg   1140
 taaagaagtt gcaacagatg tcagactatt gcctcaagga acagtcattt ttgaagatat   1200
 cagcattgaa cattttgaag gaactgtaac caaagttatc ccaaaagtac ccagtaaaaa   1260
 ccagaatgac ccattgccag gacgcatcaa agttgacttt gtgatcccta aagaacttcc   1320
 ctttggagac aaagatacga aatccaaggt gaccctgctg gaaggtgacc atgttaggtt   1380
 taatatttca acagaccgac gtgacaaatt agagcgagca accaatatag aagttctgtc   1440
 aaatacattt cagttcacta atgaagcccg agaaatgggt gtgattgctg ccatgagaga   1500
 tggttttggt ttcatcaagt gtgtggatcg tgatgttcgt atgttcttcc acttcagtga   1560
 aattctggat gggaaccagc tccatattgc agatgaagta gagtttactg tggttcctga   1620
 tatgctctct gctcaaagaa atcatgctat taggattaaa aaacttccca agggcacggt   1680
 ttcatttcat tcccattcag atcaccgttt tctgggcacg gtagaaaaag aagccacttt   1740
 ttccaatcct aaaaccacta gcccaaataa aggcaaagag aaggaggctg aggatggcat   1800
 tattgcttat gatgactgtg gggtgaaact gactattgct tttcaagcca aggatgtgga   1860
 aggatctact tctcctcaaa taggagataa ggttgaattt agtattagtg acaaacagag   1920
 gcctggacag caggttgcaa cttgtgtgcg acttttaggt cgtaattcta actccaagag   1980
 gctcttgggt tatgtggcaa ctctgaagga taattttgga tttattgaaa cagccaatca   2040
 tgataaggaa atctttttcc attacagtga gttctctggt gatgttgata gcctggaact   2100
 gggggacatg gtcgagtata gcttgtccaa aggcaaaggc aacaaagtca gtgcagaaaa   2160
 agtgaacaaa acacactcag tgaatggcat tactgaggaa gctgatccca ccatttactc   2220
 tggcaaagta attcgccccc tgaggagtgt tgatccaaca cagactgagt accaaggaat   2280
 gattgagatt gtggaggagg gcgatatgaa aggtgaggtc tatccatttg gcatcgttgg   2340
 gatggccaac aaaggggatt gcctgcagaa aggggagagc gtcaagttcc aattgtgtgt   2400
 cctgggccaa aatgcacaaa ctatggctta caacatcaca cccctgcgca gggccacagt   2460
 ggaatgtgtg aaagatcagt ttggcttcat taactatgaa gtaggagata gcaagaagct   2520
 ctttttccat gtgaaagaag ttcaggatgg cattgagcta caggcaggag atgaggtgga   2580
 gttctcagtg attcttaatc agcgcactgg caagtgcagc gcctgtaatg tttggcgagt   2640
 ctgtgagggc cccaaggctg ttgcagctcc tcgacctgat cggttggtca atcgcttgaa   2700
 gaatatcact ctggatgatg ccagtgctcc tcgcctaatg gttcttcgtc agccaagggg   2760
 accagataac tcaatggggt ttggtgcaga aagaaagatc cgtcaagctg gtgtcattga   2820
 ctaaccacat ccacaaagca caccattaat ccactatgat caagttgggg ggaatctggt   2880
 gaagggttct gaatatctcc ctcttcatcc ctcccgaaat ctggaatact tattctattg   2940
 agctattaca ccagttttaa caccttcctc gtgttatgtt taaaaaaata aataaattta   3000
 agaaaaccat tttaaataat gcacagttgc agcctggaaa aacttaaggt ggcgccttat   3060
 agtatcaatt ttaggagctt tatttggtgc atttaacgca actggtaatt gcagaatcca   3120
 ctttgcctgt gtaagtgaaa aatatagact gttatcttgt tggccctatg aaattctgca   3180
 cttttcatta tatactctac cttcattaat tacttctggc aagatgttct gccttagcac   3240
 tcagttgcat tcttttcctt tttcttcctg ttcattatgc tttaattctg aggaccatat   3300
 gagggtagaa tatattatct tttaaaaatt acaaaaattt gtataggcaa accatttctt   3360
 aaagttgatg gccaaatttt aaaatgttat ttttcatatc atttataatc ttgtcacaat   3420
 ccacttaaag aagtttggtt atatttcagt gaaaattttc ttccagagta ggtttttttt   3480
 cgtgggttgg ggggtaactt tactacaatt agtaagtatg gtgcagaatt tcatgcaaat   3540
 gaggagtgcc agcagtgtga taatttaaac atatttaaac aaaaacaaaa aaaatgaatg   3600
 cacaaacttg ctgctgctta gatcactgca gcttctagga cccggtttct tttactgatt   3660
 taaaaacaaa acaaaaaaaa ataaaaaagt tgtgcctgaa atgaatcttg ttttttttta   3720
 taagtagccg cctggttact gtgtcctgta aaatacagac acttgaccct tggtgtagct   3780
 tctgttcaac tttatatcac gggaatggat gggtctgatt tcttggccct cttcttgaat   3840
 tggccatata cagggtccct ggccagtgga ctgaaggctt tgtctaagat gacaagggtc   3900
 agctcagggg atgtggggga gggcggtttt atcttccccc ttgtcgtttg aggttttgat   3960
 ctctgggtaa agaggccgtt tatctttgta aacacgaaac atttttgctt tctccagttt   4020
 tctgttaatg gcgaaagaat ggaagcgaat aaagttttac tgatttttga gacact       4076



      <210> 2402
      <211> 775
      <212> DNA
      <213> Homo sapiens


      <400> 2402
 atgaggctcc aaagaccccg acaggccccg gcgggtggga ggcgcgcgcc ccggggcggg     60
 cggggctccc cctaccggcc agacccgggg agaggcgcgc ggaggctgcg aaggttccag    120
 aagggcgggg agggggcgcc gcgcgctgac cctccctggg caccgctggg gacgatggcg    180
 ctgctcgcct tgctgctggt cgtggcccta ccgcgggtgt ggacagacgc caacctgact    240
 gcgagacaac gagatccaga ggactcccag cgaacggacg agggtgacaa tagagtgtgg    300
 tgtcatgttt gtgagagaga aaacactttc gagtgccaga acccaaggag gtgcaaatgg    360
 acagagccat actgcgttat agcggccgtg aaaatatttc cacgtttttt catggttgcg    420
 aagcagtgct ccgctggttg tgcagcgatg gagagaccca agccagagga gaagcggttt    480
 ctcctggaag agcccatgcc cttcttttac ctcaagtgtt gtaaaattcg ctactgcaat    540
 ttagaggggc cacctatcaa ctcatcagtg gttcaaagaa tatgctggga gcatgggtga    600
 gagctgtggt gggctgtggc tggccatcct cctgctgctg gcctccattg cagccggcct    660
 cagcctgtct tgagccacgg gactgccaca gactgagcct tccggagcat ggactcgctc    720
 cagaccgttg tcacctgttg cattaaactt gttttactgt tgattaaaaa aaaaa         775



      <210> 2403
      <211> 2228
      <212> DNA
      <213> Homo sapiens


      <400> 2403
 ggtttgcttc ctttcccagc atcaatctcc agcaaatgct aaaagaagtc cccaaaaggt     60
 ttggggatga gagaggtgcc attgttcatt acacgattct caataaccat gtttaccgga    120
 gatctttagg gaaatacaca gacttcaaga tgttctctga tgagattttg ttatcattga    180
 caagaaaggt ccttctccca gatttagaat tttatgttaa tcttggagat tggcccttgg    240
 agcatcgaaa agtcaatgga acccctagcc ccatacctat catttcatgg tgtggctctc    300
 tggattcaag agatgttgtc cttccaacgt atgacatcac ccactccatg cttgaagcca    360
 tgcggggtgt tacaaatgat ctcctctcta ttcagggaaa tacagggcct tcctggatca    420
 ataaaacaga gagagctttc ttcagaggta gagacagccg agaggagagg ctccagttgg    480
 tacagctgtc caaagaaaat cctcagctac tagatgcagg aattacagga tatttctttt    540
 tccaagagaa agaaaaggag cttggaaaag ccaagttgat gggtttactt gatacttgta    600
 cttaaagaaa tgtggatggg accgtggctg cttacagata tccatatctc atgctgggcg    660
 acagtctggt tttaaagcag gactcgccat attatgaaca tttctacatg gcactagaac    720
 cttggaagca ttatgttcca attaaaagaa atctgagtga tttattagag aaagttaaat    780
 gggctaagga aaatgatgaa gaagccaaga agattgcaaa agaaggacag ttgatggcta    840
 gggacctact acagccacac aggctttact gctactatta ccaagtactg cagaaatatg    900
 ccgagcgcca gtccagcaaa cccgaagtac gtgatggaat ggaacttgtt cctcagccag    960
 aagatagcac agccatctgc cagtgccaca ggaaaaagcc ttcaagagaa gaactttgag   1020
 tcagcccaga atcacactcc tgtgtatccc ggctacactt taaggaaaga ttgaatctaa   1080
 gctgtgaagg acagtataga agactgcacc aagtggacta gttctcccgg tggctttata   1140
 tatgtagatg gatatagcag tactggttga gtatccctca tctgaaatgc ttaggaccag   1200
 gagtgtttca ggcttcagat tttttaagat ttgggaatat ttgcatgtac ataatgaggt   1260
 atcttgggga tgagatccaa gtctaaacac aaaattcatt tatattttat atataccttg   1320
 ttcacatacc ctgaaggtaa ttttatataa tatttttaat aatttgtgca tgaaacaaag   1380
 tttgtataca ttgaactgtc agaaagcaaa ggtgtcacta tcttagcgac ccaagtggtg   1440
 gtgtcagcac tcaaaaagtt ttggattttg gggtatttca gattttagat ttttgtatga   1500
 ggaatgttca acctgtattt gaacgaagca ttaccaaata tcgattgaat attaatatct   1560
 tttgcgtaaa aactgctatt atcagcatca tagtttctct aaaaagaaaa cttggggatc   1620
 atagccgata gagagacttg ctaaaatata aatcagcctc tgcaaaactg tttacatatt   1680
 tattggttta catattttat tggtttattt ctatcccctg ttcacttttt ctcttccact   1740
 tccaattatg aagagaaaat atttgttcag ggttgtcccc ccgccccccg tcactgcata   1800
 atttctcctc ttacaagctg cttttggctt tcattaataa cagcttcctt ttagaaggtc   1860
 tgataaggat atttaaggaa gaagagaatg actctgttat taaaggtggc atggagactg   1920
 tggagggaat attttttaaa gcactactca tatcctttaa actaaatttt gccaaagccc   1980
 gagacaacat taaggagaaa ttgtacctta agttagtaat tccaaatcta tctgagttgt   2040
 atacccatca aagacaatac agttattaac atagatgaag gtatgctata ggcatcattc   2100
 attatctcta tattgaatag gtgaaagata actgtagtca ggtgaaaggc attcattatt   2160
 tttaagctga aaaggggatc cttgaaaaca ctgaaaacct ctacaacaat cttcaggaag   2220
 cctgcttg                                                            2228



      <210> 2404
      <211> 3965
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(3965)
      <223> n = a,t,c or g


      <400> 2404
 gacgggctgg ggaggtggtg ccaggctggt tgctagctgc cgccgctgct caccccggcc     60
 gtccggccgc ttcattgtca ccgggcctcg gggcagtgtt gggggtggcg gggcgccagg    120
 tcgccgaccc gaggtttcgg cgcgactggt tccgcatccc ctccccgccg gccgaatctg    180
 caggccccgc gcgccaggca ggcttcgcgg ctgcgccccc ggcccgcgca ggacctgcct    240
 tgtccaccat gaaaggcacc cgggccatcg gcagcgtccc ggagcgcagc ccagcaggtg    300
 tggacctgag tctgacaggt ctccctccgc ctgtgtcccg gcgtcctggc agtgccgcca    360
 ccaccaagcc catcgtccgc tctgtctccg tggtcacagg cagcgagcag aagaggaagg    420
 tgctggaggc cacagggcct gggggctccc aggccatcaa caaccttaga agatccaaca    480
 gcaccacgca ggtcagccag cctcggagcg gctcccccag gccaacggag cccacagact    540
 tcctgatgct cttcgagggc agccccagtg ggaaaaagag gcctgccagc ctgagcacag    600
 cccccagcga gaagggagcc acctggaacg tcctggatga ccagccccgg ggcttcacct    660
 tgccatccaa tgcccggagt tccagtgccc ttgactcacc agcgggcccg cggaggaaag    720
 aatgcaccgt ggccctggcc cccaacttca ctgctaacaa caggagcaac aagggagcag    780
 tgggcaactg cgtcaccacc atggtgcaca accgctacac cccctcggag agggcgcctc    840
 cgctcaagag ctccaaccag actgccccct ccctcaacaa catcatcaag gcagccacct    900
 gtgagggcag tgagagcagc ggctttggga agctgccgaa gaatgtctcc agtgccaccc    960
 actcagcccg gaacaatact gggggcagca cgggcttgcc caggcggaag gaggtgacgg   1020
 aggaggaggc tgagaggttt atccaccagg tgaaccaggc cgctgtcacc atccagcgct   1080
 ggtaccggca ccaggtgcag cggcgcggag caggagctgc ccgcctggag cacttgcttc   1140
 aggccaagcg ggaggagcag cggcagcggt caggcgaggg gaccctcttg gacctgcacc   1200
 agcagaaaga ggcagccagg aggaaggccc gggaggagaa ggcacgccaa gccaggcgag   1260
 cagccattca ggagctgcaa cagaaacgag ccctgagagc ccagaaggcg agcactgccg   1320
 agcgtgggcc acctgagaat cccagggaga ccagagtgcc aggaatgcgg cagcctgctc   1380
 aggagctgtc ccccacgcca ggcggcactg cccaccaggc cctcaaggcc aacaatgctg   1440
 gtggtggcct ccctgctgca ggccccggag accgctgcct gcccacctcc gactcatccc   1500
 cagaaccaca gcagcctcca gaggacagga cgcaggacgt tacttgccca ggatgcagct   1560
 ggggacaacc tggagatgat ggccccgagc agggggagcg ccaagtccag ggggccactg   1620
 gaggagctgc tgcacacact gcagctgctg gagaaggagc cggacgcgct gccccgcccc   1680
 aggacccatc acaggggcag atacgcctgg gccagcgagg tgaccacgga ggatgacgcc   1740
 agctctctga cagctgacaa cttggagaaa tttggaaaac tcagtgcgtt ccccgaacct   1800
 cctgaggatg ggacgctgct atcggaggcc aagctacaaa gcatcatgag cttcttggac   1860
 gagatggaga agtctgggca ggaccagctg gactcccagc aggaggggtg ggtgccggag   1920
 gcggggccgg ggcccctgga gctggggtcc gaggtgagca cgtctgtgat gcggctgaag   1980
 ctggaggtgg aggagaagaa gcaggccatg ctgctgctgc agagagcgct ggcgcagcag   2040
 cgagacctca cggcccggcg ggtcaaggag acagagaagg cactgagccg gcagctgcaa   2100
 cggcagaagg aggccctacg aggccaccat ccagcggcac ttggccttca ttgaccagct   2160
 gattgaggac aagaaggtcc tgagtgaaaa gtgcgaggct gtggtggccg agctgaagca   2220
 ggaggaccag agatgcaccg agcgtgtggc ccaggcacag gcgcagcacg agctggagat   2280
 taaaaaactc aaagaattaa tgagcgccac cgagaaagcc cgccgggaga agtggatcag   2340
 tgagaaaacc aagaagatca aggaggtcac tgtccgaggt ctggagcccg agatccagaa   2400
 gctgattgca aggcacaagc aggaagtgcg gaggctcaag agcctgcacg aggcggagct   2460
 gctgcagtcg gatgagcggg cctcgcagcg ctgcctgcgc caggccgagg agctgcggga   2520
 gcagctggag cgggagaagg aggcgctggg ccagcaggag cgcgaacgtg ctcggcagcg   2580
 gttccagcag cacctggagc aggagcagtg ggcgctgcag cagcaacggc agcggctgta   2640
 cagtgaggtg gctgaggaga gggagcggct gggccagcag gcagccaggc agcgggcgga   2700
 gctggaagag ctgaggcagc agctggagga gagcagctct gcactgaccc gagccctgag   2760
 ggctgagttt gagaagggca gggaggagca ggagcgccgg caccagatgg agctgaatac   2820
 cctgaagcag cagctggagc tggagaggca ggcgtgggag gccggccgca ccaggaagga   2880
 ggaggcgtgg ctgctgaacc gggaacagga gctgagggaa gaaatccgga aaggccggga   2940
 caaggagatt gagctggtca ttcaccggct ggaggccgac atggcgctgg ccaaggagga   3000
 gagtgagaag gctgccgaga gccgcatcaa gcgcttacgg gacaagtacg aggccgagct   3060
 ctccgagctg gagcagtcgg agcggaagct tcaggagcgg tgctcggagc tgaagggcca   3120
 gcttggggag gccgagggcg agaatctgcg tctgcagggc cttgtgcggc agaaggagcg   3180
 ggcgctggag gatgcgcagg cggtgaacga gcagctttct agcgagcgca gcaacctggc   3240
 ccaggtgatc cgccaggagt tcgaggaccg ggctggcagc ctctgaggag gagacgcggc   3300
 aggccaaggc cgagctggcc acgctgcagg cccgccagca gctggagctg gaggaggtgc   3360
 accggagggt gaagacagcc ctcgcgagga aggaggaggc cgtgagcagc ctccggacac   3420
 aacataaggg ttcgggtgaa gcgggccgac cacctggagg agctgctgaa gcagcacagg   3480
 aggcccacgc caagtaccaa gtgtccaggg atgccgggaa cactgtttaa gaacggaagg   3540
 caaaggacaa aggctggacg tgggcccaga ggcccacagg gacgcccacc tgccccccac   3600
 agaggctggt ggttgagatg cccacggcta agcacctgtg gctgcatttt aacagtaaag   3660
 gaggccgttg ttttcagcaa aaaaaaaaaa aagggggcgc ccttttaaaa gaatcaattt   3720
 ttattcccgg gggcgggaaa ggaaaaattt tttttttggg gccccaaaat taaattccgg   3780
 ggccggtttt ttaaaacggt ggggggggaa aaacccgggg gttccccaat ttaaaccgtt   3840
 tgggaaaaan gnnnnnnnnn nngnnnnaan nangnntnct tnntgagata tttttttgtc   3900
 ttgcctacac gggtggggtt ttgattttag ttaaaaccat tggggggttt ggaaaatact   3960
 caaag                                                               3965



      <210> 2405
      <211> 2064
      <212> DNA
      <213> Homo sapiens


      <400> 2405
 atgacagcct ccataaggag gtatcacacg tgtgctacag atggagaacc agactcgagt     60
 gtgcttgtcg gaggggatgg tgacctgacc ctgctggtgg cagccctggg tttggacctg    120
 ggtctgccct tcatgctgct gccgcccctc atggagtgga tgcgcgtggc catcacctac    180
 gcagagcacc gccgcagcct caccgtggac agcggcgaca tccggcaggc agcccggctg    240
 ctgctgcctg acccgaacac tgtttcagtt ccttccggga ggctggatgc ccgagcagct    300
 actgaaaaat tcaaccagga cctgggtttc cgcatgctca actgtgggag gacggacctc    360
 atcaaccaag ccatcgaggc cttgggtccg gatggggtta acaccatgga tgaccagggt    420
 atgacgccac tgatgtacgc ctgcgctgct ggggacgaag cgatggtcca gatgttgatt    480
 gatgctgggg caaacttgga catccaggtt ccaagcaact cccccaggca cccttccatc    540
 caccccgaca gccggcactg gacctcactg acattcgctg tgctgcatgg acacatctct    600
 gtggtccagt tgctgctgga tgctggtgcc catgtcgagg gctcggcagt gaacggcggc    660
 gaggacagct atgcggagac gcccctgcag ctggcctctg cggcagggaa ctatgagctg    720
 gtcagtttgt tgctgagccg aggcgccgac cccctcctca gcatgctgga ggcccacggc    780
 atgggctcct ccctccacga ggacatgaac tgcttcagcc actcagctgc ccacggccac    840
 agaggtatat ggggattggt gaccctggga cccctggcct gcctggagga ggaagaccat    900
 gaaactccga gccctcgggt accccagagc agcccgtcgg ggcaggaggg cactggggga    960
 cagctcagga acgtcctgag gaagctcctg acgcagccac agcaggctaa agcggacgtg   1020
 ctgtccctgg aggagatcct ggccgagggt gtggaggaaa gtgatgcgtc gagccagggc   1080
 agtggcagcg aggggcccgt gcggctgagc cggacccgca ccaaggccct acaggaggcc   1140
 atgtactaca gcgctgagca cggctacgtg gacatcacca tggagctgag ggcactggga   1200
 gtcccctgga agctgcacat ctggatcgag tctctgagga cctcgttctc gcagtcgcgg   1260
 tactcggtgg tgcagagcct cctgcgggac ttcagctcca tcagagagga ggagtacaac   1320
 gaggagctgg tgaccgaggg cttgcagctc atgttcgaca tcctcaagac cagcaaaaac   1380
 gactccgtca tccagcaact ggctaccatc ttcacccact gctatggcag cagtcccatc   1440
 cccagcatcc cagagatccg gaagaccctg ccggccaggc tagatccaca ctttttgaac   1500
 aataaggaga tgtcagatgt gaccttcctg gtggaaggaa agctgtttta tgcacataaa   1560
 gtcctgctgg tgacagcttc taacaggttc aagacactaa tgaccaataa atcagaacag   1620
 gatggggaca gcagcaagac catcgagatc agcgacatga agtaccacat ttttcagatg   1680
 atgatgcagt atctgtacta cggaggaaca gaatccatgg agatccccac cactgacatc   1740
 ctggagctgc tgtcagctgc cagcctgttc cagctggatg ccctgcagag gcactgcgag   1800
 atcctgtgct cccagaccct cagcatggag agtgccgtga acacctacaa atatgccaag   1860
 atccacaatg ccccagaact ggccctgttc tgtgagggct tcttcctcaa gcacatgaag   1920
 gccctactgg agcaggatgc cttccggcag ctcatctacg gccgcagcag caaagtgcag   1980
 ggcctggatc cactgcagga cctgcagaac accctggcag agcgcgtgca ctctgtctac   2040
 atcacctccc gggtcagcag ctga                                          2064



      <210> 2406
      <211> 571
      <212> DNA
      <213> Homo sapiens


      <400> 2406
 tttcgtccgg gacgcagggc aaagcgagcc atggctgtct acgtcgggat gctgcgcctg     60
 gggaggctgt gcgccgggag ctcgggggtg ctgggggccc gggccgccct ctctcggagt    120
 tggcaggaag ccaggttgca gggtgtccgc ttcctcagtt ccagagaggt ggatcgcatg    180
 gtctccacgc ccatcggagg cctcagctac gttcaggggt gcaccaaaaa gcatcttaac    240
 agcaagactg tgggccagtg cctggagacc acagcacaga gggtcccaga acgagaggcc    300
 ttggtcgtcc tccatgaaga cgtcaggttg acctttgccc aactcaagga ggaggtggac    360
 aaagctgctt ctggcctcct gagcattggc ctctgcaaag gtgaccggct gggcatgtgg    420
 ggacctaact cctatgcatg ggtgctcatg cagttggcca ccgcccaggc gggcatcatt    480
 ctggtgtctg tgaacccagc ctaccaggct atggaactgg agtatgtcct caagaaggtg    540
 ggctgcaagg ccttggtgtt ccccaagcaa a                                   571



      <210> 2407
      <211> 5186
      <212> DNA
      <213> Homo sapiens


      <400> 2407
 atggtctcag cccaaaatct ccttaagctg ataagcaact tcagcaaagt ctcaggagac     60
 aaaatcaatg tgcaaaaatc acaagcattc ctctccagca acaacaggca aacagagagc    120
 caaatcatga gtgaactccc attcacactt gctacaaaga gaataaaata cctaggaatc    180
 caatctacaa gggaagtgaa ggacctcttc aaggagaact acaaaccact actcaatgaa    240
 ataaaagagg ataccaaaaa aatggaagaa cattccatgc tcatggatag gaagaatcaa    300
 tattgtgaaa atggccatac tgcccaagaa gggaaaactt aacaaacaga aaggacaacc    360
 acacccaaaa acccatcttg tacatcaccc atcattcaaa gacccaaaag taaataaaac    420
 ccaccaaaga tggggaaaaa aacagaacag aaaaactgga aactctaaaa tgtagagtgc    480
 ctctcctcct ccaaaggaaa gcagttcctc accagcaacg gaacaaagct ggatggagaa    540
 tgactttgac gagctgagag aggaaggctt cagacgatca aattactccg agctacagga    600
 ggaaattcaa accaaaggca aagaagttga aaactttgaa aaaaatttag aagaatgtat    660
 aactagaata accaatacag agaagtgctt aaaggagctg atggagctga aaaccaaggc    720
 tcaagaacta cgtgaagaat gcagaagcct caggagccga tgcgatcaac tggaagaaag    780
 ggtatcagtg atggaagatg aaatgaatga aatgaatgaa atgaagtgag aagggaaggt    840
 tagagaaaaa agaataaaca gaaatgagca aagcctccaa gaaatatggg actatgtgaa    900
 aagaccaaat ctacatctga ttggtgtacc tgaaagtgat ggtgagaatg gaaccaagtt    960
 ggaaaacact ctgcaggata ttatccagga gaacttcccc aatctagcaa ggcaggccaa   1020
 cattcagatt caggaaatac agagaacgcc acaaagatac tcctcgagaa gagcaactcc   1080
 aagacacata attgtcagat tcaccaaagt tgaaatgaag gaaaaaatgt taagggcagc   1140
 cagagagaaa ggtcgggtta cccacaaagg gaagcccatc agactaacag cggatctctc   1200
 ggcagaaact ctacaagcca gaagagagtg ggggccaata ttcaacattc ttaaagaaaa   1260
 gaattttcaa cccagaattt catatccagc caagctaagc ttcataagtg aaggagaaat   1320
 aaaatacttt acagacgatc aaatgctgag agattacata atggtaaagg gatcaattca   1380
 acaagagctc ctgaaggaag cgctaaacat gcacccaata caggagcacc cagattcata   1440
 aagcaagtcc ttagtgacct acaaagagac ttagactccc acacattaat aatgggagac   1500
 tttaacaccc cactgtcaac attagacaga tcaacgagac agaaagtcaa caaggatacc   1560
 caggaattga actcagctct gcaccaagca gacctaatag acatctacag aactctccac   1620
 cccaaatcaa cagaatatac atttttttca gcaccacacc acacctattc caaaattgac   1680
 cacatagttg gaagtaaagc actcctcagc aaatgtaaaa gaacagaaat tataacaaac   1740
 tgtctctcag accacagtgc aatcaaacta gaactcagga ttaagaaact cactcaaaac   1800
 cgctcaacta catggaaact gaacaacctg ctcctgaatg actactgggt acataacgaa   1860
 atgaaggaaa aaataaagat gttctttgaa accaacgaga acaaagacac aacataccag   1920
 aatctctggg acacattcaa agcagtgtgt agagggaaat ttatagcact aaatgcccac   1980
 aagagaaagc aggaaagatc caaaattgac accctaacat cacaattaaa agaactagaa   2040
 aagcaagagc aaacacattc aaaagctagc agaaggcaag aaataactaa aatcagagca   2100
 gaactgaagg aaatagagac acaaaaaacc cttcaaccct tcaaaaaatt aatgaatcca   2160
 ggagctggtt ttttgaaagg atcaacaaaa ttgatagacc gctagcaaga ctaataaaga   2220
 aaaaaagaga gaagaatcaa atagacacaa taaaaaatga taaaggggat atcaccactg   2280
 atcccacaga aatacaaact accatcagag aatactacaa acacctctac gcaaataaac   2340
 tagaaaatct agaagaaatg gataaattcc tcgacacata caccctccca agactaaacc   2400
 aggaagaagt tgaatccctg aatagaccaa taacaggagc tgaaattgtg gcaataatta   2460
 atagcttacc aaccaaaaaa agtccaggac cagatggatt cacagccgaa ttctaccaga   2520
 ggtacaagga ggagctggta ccattccttc tgaaactatt ccaatcaata gaaaaagagg   2580
 gaatcctccc taactcattt tatgaggcca gcatcatcct gataccaaag cctggcagag   2640
 acacaacaaa aaaagagaat tttagaccaa tatccctgat gaacatcaat gcaaaaatcc   2700
 tcaataaaat actggcaaac caaatccagc agcacatcaa aaagcttatc caccatgatc   2760
 aagtgggctt catccctggg atgcaaaaat cctcaacata tgcaaatcaa taaacataat   2820
 ccagcatata aacagaacca aagacaaaaa ccacatgatt atctcaatag atgcagaaaa   2880
 ggcctttgac aatatatgca aatcaataca tgcaataaat taggtattga tgggacatat   2940
 ctcaaaataa taagagctat ttatgacaaa cccacagcca atagcatact gaatgtgcaa   3000
 aaactggaag cattcccttt gaaaactggc acaagacagg gatgccctct ctcacctcac   3060
 cactcctatt caacatagta ttctgcccca tagtgttctg gccagggcaa tcaggcaaga   3120
 gaaggaaata aagggtattc aattaggaaa agaggaagtc aaattgtccc tgtttgcaga   3180
 cgacatgatt gtatatctag aaaaccccat tgtctcagcc caaaatctcc ttaagctgat   3240
 aagcaacttc agcaaagtct caggatacaa aatcaatgta caaaaatcac aagcattctt   3300
 atacaccaat aacagacaaa cagagagcca aatcatgaat catgagtgaa ctcccattca   3360
 caattgcttc aaagagaata aaatacctag gaatccaact tacaagggat gtgaaggacc   3420
 tcttcaagga gaactacaaa ccactgctca gtgaaataaa agaggataca aacaaatgga   3480
 agaacattcc atgctcatgg gtaggaagaa tcaatattgt gaaaatggcc atactgccca   3540
 aggtaattta tagattcaat gccatcccca tcaagctacc aatgactttc ttcacagaat   3600
 tggaaaaaac tactttaaag ttcatatgga accaaaaaag agcccacatt gccaagtcaa   3660
 tcctaagcca aaagaacaaa gctggaggca tcacgctacc tgacttcaaa ctatactaca   3720
 aggctacagt aaccaaaaca gcatggcact ggtaccaaaa cagcatggta ctggtaccaa   3780
 aacagagata cagaccaatg gaacagaaca gagccctcag aaataatgcc gcatatctac   3840
 actattctga tcctttggac aaacctttgc ttgagaaaaa caagcaatgg gggaaaggat   3900
 tccctaattt ataaaatggc tgctggggaa aactggctag cccatatgta ggagaaagct   3960
 gaacctggca tcccttccct taccccttat acaaaaatca attcaagatg gattaaagac   4020
 ttaaatgtta gacctaaaac cataaaaacc ctagaagaaa acctaggcaa taccattcag   4080
 gacataggca tgggcaagga cttcatgtct aaaacaccaa aagcaatggc aacaaaagcc   4140
 aaaattgaca aatgggatct aattaaacta aagagcttct gcacagcaaa agaaactacc   4200
 atcagagtga acaggcaacc tacagaatgg gagaaaattt tcgcaaccta ctcatctgac   4260
 aaagggctaa tatccagaat ctacaatgaa ctcaaacaaa tttacaagaa aaaaacaaac   4320
 aaccccatca aaaagtgggt gaaggatatg aacagacact tctcaaaaga agacatttat   4380
 gcagccaaaa gacacatgaa aaaatgctca tcatcactgg ccatcagaga aatgcaaatc   4440
 aaaaccacaa tgagatacca tctcacacca gttagaatgg caatcattaa aaagtcagga   4500
 aacaacaggt gctggagagg atgtggagaa ataggaacac ttttacactg ttggtgggac   4560
 tgtaaactag ttcaaccatt gtggaagtca gtgtggcgat tcctcaggga tctagaacta   4620
 gaaataccat ttgacccagc catcccatta ctgggtatat acccaaagga ttataaatca   4680
 tgctgctata aagacacatg cacacgtatg tttattgcgg cactattcac aatagcaaag   4740
 acttggaacc aacccaaatg tccaacaatg atagactgga ttaagaaaat gtggcacata   4800
 tacaccatgg aatactatgc agccataaaa aatgatgagt tcatgtcctt tgtagggaca   4860
 tggatgaaat tggaaaccat cattctcagt aaactatcgc aagaacaaaa aaccaaacac   4920
 cgcatattct cactcatagg tgggaattga acaatgagat cacatggaca caggaagggg   4980
 aatatcacac tctgggggac tgttgtgggg tggggggagg gggggaggga tagcattagg   5040
 agatatacct aatgctaaat gacgagttaa tgggtgcagc acaccagcat ggcacatgta   5100
 tacatatgta actaacctgc gcattgtgca catgtaccct aaaacttaaa agtataatta   5160
 aaaaaaaata aaataaaaat aaaaaa                                        5186



      <210> 2408
      <211> 1356
      <212> DNA
      <213> Homo sapiens


      <400> 2408
 atggtgaagc tctctattgt cctgacccca cagttcctgt cccatgacca gggccagctc     60
 accaaggagc tgcagcagca tgtaaagtca gtgacatgcc catgcgagta cctgaggaag    120
 gtgtctctcc tgaagactat cttctggtct cgaaatggac atgatggatc cacggatgta    180
 cagcagagag cctggaggtc caaccgccgt agacaggaag ggctgaggtc catttgtatg    240
 cacacaaaga aaagagtttc ttcctttcga ggaaataaaa ttggcctgaa agacgtcatt    300
 actctacgga gacatgtgga aacaaaagtt agagctaaaa tccgtaagag gaaggtgaca    360
 acgaaaatca accatcatga caaaatcaat ggaaagagga agaccgccag aaaacacact    420
 ggtgactgtc atccgggtga ggtggtgggc caagcccact tcgttcccga ttctccggtt    480
 cacattgccc tccatggtat ggcgcagcca ttgtttggca tccagggggg cgccctggaa    540
 cctgcgggtc gcggcacagg ttttttggat tctccagtgt ttcgacccat tcggaagtat    600
 aacgtccaga tccccccttc tgcaagaaag gctctttgca actggtctct gctgctggtg    660
 tgtgtgggga agcctgagat cttcgtagcg atacactact atacaccaaa cacaaagctg    720
 gtgccattgg cacgacctag aaacagccat gttcctcatc ccccagagcg caccacggtc    780
 actcagtaca gcacgtgtgc gctgcttact gccctgtgcc tgctgctgcc tgtgctgcag    840
 gaaacagccc agagtcgaag gatggtcacc agccacccgg aagacagtcc tgctctggca    900
 cgcaaacacg gagcatcgca accggccggc ctcggctttc caagaactca gactgtcact    960
 cccgccttca cattccagac cccaacagca gctgagcccg cacttctgag cgcgtggctg   1020
 ggtagagctc cagaaactga gacaatcaca gacatggcag gctctgcagc agccgccccc   1080
 acctgtgaaa tgttaagagc tcatggccat gatgacctct actttaaatg ggaaccttgt   1140
 gcctcctccc aagctatcac tgtgctcccg aaacacagcg gaactggtgg aagccgccag   1200
 ggccctgccg tggcccaccc cgcagccccc tttcccaagg tgcgaggtgg agagggtacg   1260
 tactacttgc acctgtccgt cttctccgat ctggtggatc tgcacctgct gcacgttggc   1320
 cagcgcgtag tgcagggcct gcggctgcgg ctgtga                             1356



      <210> 2409
      <211> 2171
      <212> DNA
      <213> Homo sapiens


      <400> 2409
 ctaggcagtt acagtctgta gctgtaccat tgaggggatc ggggcaagat ggaaatttcc     60
 atggcttacc agaaacaggt gagaaactgc ctgctggtag cctgctgcaa gacaaggagg    120
 cccccaaaag agaggagata catgatccct taattcaggc tcaggctgaa gaactgaccc    180
 acttacaaca gaagatacag gaagggagag gtgtctgcta ccttttcacc cagcatgtga    240
 agaacacagt caagtctttt gagggccttc tcaggaacac tgacattgcc tactaccaga    300
 gacagagatt ctgtgagcaa atggtacaag gaagccagct gacagagatc cttgtcagaa    360
 aacttgccac agaatactgt cttactagtg caaatcgatg gcagttggtt cagttcagaa    420
 aactcacatg tggaaaggca atttcctgtg tgtcacattt gtgggaactt cacttcccca    480
 aaccaacctc tctggcacct gtattcacca ctgtcattga cactggcaga ggtgattctg    540
 tagctggggg tcgaggtctg agtggctgtg ccattgagaa accactgtgt ggagctgctc    600
 ccaggcagat ggagcacctc acagtgcaag gttacggttt cctcttggaa cacgctgacc    660
 catggaggct gcaaagtgat cactgccttt gtggtgtcta cttggagatt acaagaagaa    720
 aaagaaaaag atcaagtgga gtaaagggga gggctctgag caactgcccg ccagatgcac    780
 aagtcaaaac tgatctagag attctgaagt acgctgtgct ccttgagaag tgcggagcca    840
 ctggaaccac aagcagcttc agacaggaac caatgaggcc atcaaaaccc tcaacagagg    900
 catctacccc tgcagggctg cagagcctct gtactgggcg gcatcccagc ctgagtgcca    960
 gagctcagtg ggcaggcccc cgagcaagta gagaggaggg caccttttgg acagaacctg   1020
 tgggacaaga gcgacgtctc atccgttcag gttcctcaca aaatgagagt caggaagatc   1080
 agggtgcaga cctgatttcc cacgaagggc tgaaagcaga caaccagagg gagagcagca   1140
 cctgggccaa tgagtggctc agcggtaagc ccaaggtcca gcacacgaat caggaaactg   1200
 atggttcttg ggttagcagg aatccgccca gagaacagat gaaagtaaca ggtaccaata   1260
 tcaaaactgc agtgactcac cagaaacact acgtgcttgc cactttgctt agcggtttgt   1320
 tgagtccaac aactgcgtgg gtcccggact cagcccgcct gcacccaggt gaaataaaca   1380
 gccttgttgc tcaaacaaag cctgtttggt ggtctcttca catggacaga agcttcaggg   1440
 ggcatttatt caattttcta ggagcccacg aggcgcaggt gagcggtgac gctgtggttc   1500
 ccaccgcacc gccgcgctcc ttggtcctct cgctgtctcc ggcgggcagt aatgttccag   1560
 cttttgcttt cccttccccc gctcccgccc taccgcccca cgacccgacc accgcccagc   1620
 tgagccccag aggctccaca gcgcagaagg tgcaccggag gtcgtgggac ccacgagcga   1680
 ccctcaccac catccctgcc ctggtggagc cccgggcgga acacaggatc cgaagatggc   1740
 agcggaagct ccgcagcagc ccaacagcga ctgggcaggg gagattagca tgtgtagagg   1800
 aagtacacat caactgcaaa tggctttctc tgagaccttc ttatctgctt tatctggatc   1860
 cagtaggggc cgacctgctg gaaaagaatc ttgctgagat gcagaacctg cgccagcgcc   1920
 tggaggagtc catcagtctc aatgaccgcc tgagggagag gctggagcat gtgcttagca   1980
 atggtgacca aggaaaagat aatcagagag tcactagctg tcaactagaa agcttggtgt   2040
 ctctcttcct gtctttccca ctttcacctg ggtacggaat aggagagaag aaatgtactg   2100
 gacagtccac tgtagcccct cattcatata ctcagagtca ctcttctggc tgtggcgagg   2160
 acatcctgtg a                                                        2171



      <210> 2410
      <211> 1665
      <212> DNA
      <213> Homo sapiens


      <400> 2410
 atcgagaccc ctgtcgagtg tgcgggaatt ccaggtcata ttgttcacag agatgattat     60
 aaaatgcttt ttatgactta caaaagaaag cttagaatat tcgttagaaa tgccttatca    120
 ctgaacactt agcgtttttc tgtttcttga ttctaaaaca gtgatgacgc tgatcatggc    180
 attaatgaag tgctgatcta ctatattttt tagtttaata tgcctgttta ttcggttaac    240
 agtataaagt aatcattctg atctggcctc tttttgtttt ttttcccatt ccctccattt    300
 ttgccgcttc cgctttgcaa acatcagatc cgagatgagt ggggcaatca gatctggatc    360
 tgccctgggt gtaacaagcc tgacgatggg agtcccatga ttgggtgtga cgactgcgat    420
 gactggtacc actggccctg tgttggaatc atgactgcac ccccagaaga gatgcagtgg    480
 ttctgcccca agtgtgcgaa caagaagaag gacaaaaagc acaagaagag gaagcatcga    540
 gcccactgac gactcccgag gggctggacc aagcggggtc agcccgggct tcttccctgg    600
 cgcctctgga agggagctgg tgcaagtctg ccgtcacatc cacccccaga tgcctgtgga    660
 taaagaaccc aggaggactg aggctggaac acaccgcgca cctggattgt tcactcccga    720
 gccgccttgg cctgtggctc cgtggcagtg cgacagaagg aaactcaagc agaggcgtgg    780
 cctgggggct gcccctcctc cacttctcta ataccagtga caagtattat taataaagag    840
 cgtacatctt cccttttgat ttcctttatt ctctccaggg ccttttcatt gaggtattag    900
 atgagaagat aatgtacaaa ctgcctcaac tgtaatttaa ggatgataga gtctgtatac    960
 agttttcagc ccctttccct ctatagtaag ataatcagaa taacataaaa gaaaactcca   1020
 gttggagtac cggtaaatat ttttgtgata agaatatatg aagcttccct ccttcccccg   1080
 tttttagtac taacatgtaa aatgttcagg cttttgtgaa ataccttata ttttttaaga   1140
 aaaaggtttc tatcatgtcc tgtttgcttt tgtgcaaatt atttttgttt aatgtatttt   1200
 atatcttcgt tgcattctaa ttttgccctt ctttaaactg ctggagtctc ttctcactgc   1260
 ttgtacattt catcaacttg tataaaaact cttcagacta aaagattgcc cctaatgtaa   1320
 ataataaata tttatgaagt agttattttt taaattttta tcgtgtttaa ttctggcttt   1380
 ctctgaaatc cactgtgatt tcagccaggt ctgtaatgac gctggacaga aacaaggcta   1440
 gagaaaaagc catcgttcaa agaaatttcc cttgagctca gcctgcgcag tgcccggaaa   1500
 catggtgggg aaagggcccg agcagttgga aggaaaacaa ggcaatttaa atttagagtt   1560
 tatgacttga agttgttttg tttgttgtct attttgtttt tgtaaatttc tttgacagac   1620
 ttttactaaa aggacatgta gtttccatga aagccaaaaa aaaaa                   1665



      <210> 2411
      <211> 520
      <212> DNA
      <213> Homo sapiens


      <400> 2411
 tcttggtaga cccacgcgtc cgtgctgtgt ttctgcagct gctaccgctg ctgctctcta     60
 gggcccaagg gaaccctggg gcttctctgg acggccgccc tggggaccgg gtgaatctct    120
 cctgcggagg agtctctcat cccatccgct gggtctgggc acccagcttc ccggcctgca    180
 agggcctgtc caaaggacgc cgaccgatcc tgtgggcctc ttcgagcggg acccccaccg    240
 tgcctcccct ccagcctttc gtcggccgcc tacgctccct ggactctggt atccggcggc    300
 tggagctcct cttgagcgcg ggggactcgg gcactttttt ctgcaagggc cgccacgagg    360
 acgagagccg tacagtgctt cacgtgctgg gggacaggac ctattgcaag gcccccgggc    420
 ctacccatgg gtccgtgtat ccccagctcc tgatcccgct gctgggcgct gggttggtgc    480
 tcggactggg agctttgggc ctggtctggt ggctgcacag                          520



      <210> 2412
      <211> 1939
      <212> DNA
      <213> Homo sapiens


      <400> 2412
 cggacgcgtg ggcggacgcg tgggctggtg attaaaaagt gggcaagtca ccatcagata     60
 aatgatgcca gtcggggtac tttaagcagc tatagtcttg tattgatggt tttgcactat    120
 ttacaaaccc tacctgaacc catccttcca tccctccaaa aaatttaccc agagtctttt    180
 agtcctgcta tacagctgca ccttgtacat caagctccat gtaatgttcc tccttacctc    240
 tcaaagaatg aatcaaacct tggggacctc ttactgggct ttcttaaata ttatgctaca    300
 gaatttgact ggaatagtca aatgatttca gttcgtgaag ccaaagccat tccaaggcct    360
 gatggtattg aatggagaaa taaatacatc tgtgtagaag aaccttttga tggaacaaat    420
 acagccagag cagtgcacga aaagcagaaa tttgatatga tcaaggatca atttttaaag    480
 tcatggcaca gattgaaaaa caagagagat ttgaacagta tactacctgt aagagctgct    540
 gtcctgaaaa gataactggg cctctatttc ttaattaaat tcttcccagg aaataaagga    600
 acaatagttt cattcataat tacattgtgt ttacctccat cataggttgc ttttttcata    660
 gttcttgttt tcatgtttta tttttaaaaa gacatataaa gattgcatat tttattatga    720
 catttcctaa taaacccctt tgatttaaaa atgtattttt aaaaatgttt acattgatga    780
 tgagtaatat tgcatgtgtt ttcaggtgat cagataaaat atattttggg aaattaactg    840
 aacaaataaa aagtttttga tataacttca attaattgta ccacatgcta atcctgaaga    900
 gatgtgtaga attttggaaa gggtctaatt catacatgct taaagtataa cctacgttag    960
 atagtttgtt gtcaaagtct gttctagtaa agtgaagatt caagtcagtt gttcagttac   1020
 ttgaagcaaa acgaaatctt tcatttcagt caaatcactg cagtcatgaa atactgaaca   1080
 attgccttaa gtctttgctt gactcactgg gatagactga ggctttgggt gtgtctgtat   1140
 tagcatttca ttagtacttc acatgctttt gatgtactct tgagattgct ttaaattttg   1200
 tattgaaaca acaatacatt ttgcactgta gtaatgggag cactaactct tacaacagtt   1260
 agtgaatcgt tttaaagaat cagttcagtg tagacatttt gaaaagattg tttcctgtgc   1320
 tttacgatag cttagtgcaa tgtgcacttc tgttttactt gccattttcc tgctctgttt   1380
 tctctgtgac atgaagcaac agaaactgag atcaaagtta agattatatc ctgtttgtag   1440
 tatcagatat ttttctgtgt acaattatag gattgtaatc taaactggaa tttttaggca   1500
 gtaagtcacc acaaaatgtt ttagataaga cacaataaaa ttattataaa taaaagctta   1560
 atgtttgtaa aaaatctctt ttttagtatt tcttttttca catgaaagaa gtggtggctg   1620
 ctaaaaaaaa agctacagtg tttattaagg gtctttttga tttatgtaaa tatttgtaaa   1680
 ttggtcagtg cctgtaaatt taaatataaa aagtaacctt gaaaacagtt ttaacttttt   1740
 caaaagaact atgtccaaca ttttttagac ctgctgtagt acagttttgt acctctaacg   1800
 tatttttttt ttgcagacca aatgttaaaa cttttgcttt tctttgactt gtaaaaggtg   1860
 cacattttca ttttcttcct taagttcaaa tttttgtatg atgtcaaatg caataaaatt   1920
 tatatatgga aaaaaaaaa                                                1939



      <210> 2413
      <211> 870
      <212> DNA
      <213> Homo sapiens


      <400> 2413
 ttcaggtgga gtctgttagt ttttgagaaa gagttagggc gagtttaagg cactgtggca     60
 gctgtgagat aaagtctggt tcctccccag ctggctcagg aaatgttcgc ggatacaacg    120
 gcggccccct ctgggcatac ctgcctgtgg agcggagagt ggacggtgtg agggggaccg    180
 ggagaggcac caaatctggc ctgggggccc gagaagcttc ctctcagtga ccacaatatg    240
 aatgggaaca gcaagatggc aaaagcttgc tgagtggtac agcgccagcc tgggtagtgg    300
 cctccccagc aagttgcatg tcactagctt cctgtggctg tcactcctgg gcccaggcac    360
 ctccgaagat cagcacctcc tcatgggctc aagcgaggac aggagcccgt cacccatgag    420
 ctctcaaggg cagagccact gtcctgtctc gatggctcca ccgtgactcc agtggacttt    480
 ggacagtggg gagcaggccc aacagggcca ctcggatgtg gtcactctgg atttgggtgg    540
 atcagcacca agctagactc atccccagcc cccaggtgct gttgctgctc ctgcgtgaga    600
 ccccatccac agctgcagct gtggcagggt ggctagtggt ggccagcatg gccctgctgc    660
 agctccacgc tgtggggggc gtggccctga ccagcagcca ccccttcatg tgggccacag    720
 gggaggagct taggaagccg ccttggcaag gttccgcagg ctctgcgtct ggtgtggaag    780
 agctcacggg gaagcactcc tgcccaggac ccgaggagcc ggccaccgtt cagaaggccc    840
 cagcttgaag gcctggagag ccgcccagct                                     870



      <210> 2414
      <211> 1031
      <212> DNA
      <213> Homo sapiens


      <400> 2414
 tgctacgtgg aaagtctcag atgtattacg cctttgctca gcttaccatg aacacttcct     60
 aatgtaatat ccccagcagc agaagacaga aatgatgatt ctgtataaag atacttggct    120
 ttcagcaaac catcttcggt agatacagta acagaacttc cctgcagttt atctatggtc    180
 acagcacttt tatctgatgc atgaatatct atatttccat aaactgttcc cagacagatc    240
 acttcgcctc cttttgtttg aacatgcaat ttttgaccct taacagactg caagatacta    300
 gtcccatgct ctgtttcaat tttgcaatta tcaccctcaa tactttgaac ttttacacag    360
 ccagaccctg atgacttgat atctaaacct ccacggacgc ctgggggtgg atagtatcag    420
 acacaatggc catctcctcc agatcctcgt cgtacttcac ctgcaggccg tccaggcccc    480
 gcacgccgcc ctccacgccg cacaccgcga ccagcacgcg gtcgccatcc gggtaggtga    540
 gggggtccag gggcctcacg gccaggtggc acgggagccg cgcccgcagc cgaccaaacg    600
 ggctcacctg cagtgtccac tccttcagag ttcggcgcgc cgggccaggc ggagggacct    660
 cagtctccga tccgggccag cgctcgctcc cacctgagct gtacggcctg gcttggcaag    720
 cccagcaagc ccagcgccca gcgccagccc acagtcggac ctgacggaga cagagacgga    780
 agcagccaag ctcccaacct gagcaggggg caagcatggc gcgcctctct cgccagtcct    840
 cagaacactt cagccacagg gagggtcact tgccacggcc aatcgacttg gccactgtgc    900
 cgcctcaagt caaataggag acgtaagtca gggtttgctg aaacaagagc gagccggttg    960
 gcttgactag gcgttctaaa catcagccgc gcaatcccca ggggcaagtt gggatttgaa   1020
 agctcacgaa a                                                        1031



      <210> 2415
      <211> 560
      <212> DNA
      <213> Homo sapiens


      <400> 2415
 ccagctcaca cgtaggttct tgctcctcgg caacgcaggc tggaggcttc ctctcctgta     60
 ttcctttctg attctgacct ccaacaatgt ctggtatgac cgtatcttcc actgacatgt    120
 atacagtgtc cctactgctc tgccttttct tcaagaagtc agaccctgac cctggtccct    180
 tccagaataa cctctttcac aaccatggca cccaaagtca aagttgtatg gggagtaagg    240
 tgggagatgt tattccaggg gctgcccgac tgataagtga gactgcccag agagtccata    300
 ctattggtca gaaacagaag aatgaccagc accttcggcg tgtccaggct ctgctcagtg    360
 gacgccaggc aaaggggctg acctcagggc gctggttcct acgccagggc tggctgatag    420
 tggtgcctac ccatggggag cctcggcccc gcatgttctt cctcttcact gatgtgctcc    480
 tcatggccaa gcctcggcct acactgcacc tgctgcggag tggcaccttt gcctgcaagg    540
 ccctctaccc catggcccag                                                560



      <210> 2416
      <211> 439
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(439)
      <223> n = a,t,c or g


      <400> 2416
 cgacgatgct ggtatcgtct cgagcgcccg caatacacgt gtctgggtct cctcaccatt     60
 ctcatctcca gtctggcctt gcttccccaa tccttgagcc tggatctctt ccccatcctc    120
 ctctccagcc tctttcttgt ccttcttctc aaatgtctgg gtctccacag catcctcact    180
 tccattctta tcctggttct cccactcagg tgtttgggtc tctgcatcaa ttttacatct    240
 taactggtct tgggtctctc ccatatgtgc ctgggtttca gggagattct cacctccagc    300
 ctccctctgg tttctattcc ctagttcctg aatgttggtt ctactctcaa ctcccatccg    360
 gtcctgggtg tcccaccctg gtgtcaagat ctcgccatca gnttcactta ttactagtct    420
 ctgggttgca cactccaat                                                 439



      <210> 2417
      <211> 390
      <212> DNA
      <213> Homo sapiens


      <400> 2417
 atgactccaa agcacgacca tctggggcac gtgctgccga tctctctgca gctgctgttg     60
 gaattgtctt cctgtcttcc tgcagcctcc gccgtgtggt gtgccggctg taatgaccca    120
 tggatgacag gttacccgga caacatgcat tacaattaca agccaatgct gcatgacaga    180
 ggaggctcgg cagtgacgtt gtctgcctcg cagagttggt atgctggctg taatgctgaa    240
 aagtcagaag taaacgcgtt ccccgggacc cagggcatgc gcttcatctc agcggcttct    300
 tacaaggatt gggtgcaagt gctgcagcag aaagatgttt ccaggaacat gggaaccaag    360
 gctaggtctg catcttctct gaaaaactag                                     390



      <210> 2418
      <211> 3414
      <212> DNA
      <213> Homo sapiens


      <400> 2418
 atgatggaag gtgaaggggg agtacggatg tcacatgacc agaccgggaa caagagaaag     60
 catggtacct ctggtatttc tgtgtgtcct aatctcctcc tcttacaaga ataccagcca    120
 gattatatta gggcccacgc cagtggcctt aatttaatta gctcttcaaa ggccctaccc    180
 aaatacagtc atgttctaag tggactctgc aagatttgta gctttggacc acgtttctct    240
 ttgcattcag ataccttctt ttttgcctta tttgctcatg cagacccgga acaaatacgg    300
 aattgcgaaa cgcctgcccc acctctccaa accgagagaa aaaacgaaat gcggataaaa    360
 acgcacccta gcagcagtcc tttatacgac acccccggga ggcctgcggg gtcggatgat    420
 tcaagctcac ggggacgagc aggagcgctc tcgacttttc tagagcctca gcgtcctagg    480
 actcaccttt ccctgatcct gcaccgtccc tctcctggcc ccagactctc cctcccactg    540
 ttcacgaagc ccagtttcct cggcagcggt aggcgagagc acgcggagga gcgtgcgcgg    600
 gggccccggg agacggcggc ggtggcggcg cgggcagagc aaggacgcgg cggatcccac    660
 tcgcacagca gcgcactcgg tgccccgcgc agggtcgcga tgctgcccgg tttggcactg    720
 ctcctgctgg ccgcctggac ggctcgggcg ctggagagct tagaaaatag gtctgctgca    780
 ggtggctgta gaaaagaaat gaataagggc aatgataatg gggccttggc tatcggggga    840
 aacatggtta ttatctgggt tgatgatttt ggctggtatg ttgatagaga tactttagag    900
 caggggtccc caacacccag ccatggacag gtactggtcc atggcctgct aggaaccggg    960
 ccacacagca ggagcacatt gaacatcaag gagcaactcc ctcgatctaa aatttctagc   1020
 attggtgctt gtaatatcat ttttcaagtt gacattaatg ctatctttgg aattctcatg   1080
 gtacccactg atggtaatgc tggcctgctg gctgaacccc agattgccat gttctgtggc   1140
 agactgaaca tgcacatgaa tgtccagaat gggaagtggg attcagatcc atcagggacc   1200
 aaaacctgca ttgataccaa ggaaggcatc ctgcagtatt gccaagaagt ctaccctgaa   1260
 ctgcagatca ccaatgtggt agaagccaac caaccagtga ccatccagaa ctggtgcaag   1320
 cggggccgca agcagtgcaa gacccatccc cactttgtga ttccctaccg ctgcttagtt   1380
 ggtgagtttg taagtgatgc ccttctcgtt cctgacaagt gcaaattctt acaccaggag   1440
 aggatggatg tttgcgaaac tcatcttcac tggcacaccg tcgccaaaga gacatgcagt   1500
 gagaagagta ccaacttgca tgactacggc atgttgctgc cctgcggaat tgacaagttc   1560
 cgaggggtag agtttgtgtg ttgcccactg gctgaagaaa gtgacaatgt ggattctgct   1620
 gatgcggagg aggatgactc ggatgtctgg tggggcggag cagacacaga ctatgcagat   1680
 gggaggacat ctgcaatctt tggctatgac cacgactgta aagtgcatga cgcttttgct   1740
 ctgtcatcag tattagttga caggcaagaa tggggctcca cttacgaatc tggggcagga   1800
 caaggtattg ctgcattttg gggagcgtgc tggaaggagg agcagagttt gttgtttttg   1860
 cttcctgata tggactggct gtgtctccat tcaaatatca acttcaatta tatctcccag   1920
 aattcccaca tgttgtggag ggacccaggg gagatagatt ccaagaaatt gagtgcttta   1980
 tcttcactac ctggaatagt actggcactt ggtaaagcac agcgaatatt gttgattgaa   2040
 ttactagggg ttggcttaga gagtgaagac aaagtagtag aagtagcaga ggaggaagaa   2100
 gtggctgagg tggaagaaga agaagccgat gatgacgagg acgatgagga tggtgatgag   2160
 gtagaggaag aggctgagga accctacgaa gaagccacag agagaaccac cagcattgcc   2220
 accaccacca ccaccaccac agagtctgtg gaagaggtgg ttcgagaggt gtgctctgaa   2280
 caagccgaga cggggccgtg ccgagcaatg atctcccgct ggtactttga tgtgactgaa   2340
 gggaagtgtg ccccattctt ttacggcgga tgtggcggca accggaacaa ctttgacaca   2400
 gaagagtact gcatggccgt gtgtggcagc gccacaaact gcacatttga tttgaaaaag   2460
 tcatggtcat ctggaggtca aattcagatg gcagactcaa ttcagagaaa aggagctgaa   2520
 ctagaagcta tttgccaaaa gaggttttct cagaggaaac acaggtatgg aaaatgtttc   2580
 gttggtgtct tggccccagt gatggaggag cattttgtga taggaacgtt gggtgcagca   2640
 tcgccattta tgaataaact gaaagctaac ctgtgttact tcaccccaga aaacagagct   2700
 ctggcagttc ctacaacagc agccagtacc cctgatgccg ttgacaagta tctcgagaca   2760
 cctggggatg agaatgaaca tgcccatttc cagaaagcca aagagaggct tgaggccaag   2820
 caccgagaga gaatgtccca ggtcatgaga gaatgggaag aggcagaacg tcaagcaaag   2880
 aacttgccta aagctgataa gaaggcagtt atccagcatt tccaggagaa agtggaatct   2940
 ttggaacagg aagcagccaa cgagagacag cagctggtgg agacacacat ggccagagtg   3000
 gaagccatgc tcaatgaccg ccgccgcctg gccctggaga actacatcac cgctctgcag   3060
 gctgttcctc ctcgggtagg tctcgctgca gccgagttca cacttcaggt cacagcacag   3120
 acacctcgtc acgtgttcaa tatgctaaag aagtatgtcc gcgcagaaca gaaggacaga   3180
 cagcacaccc taaagcattt cgagcatgtg cgcatggtgg atcccaagaa agccgctcag   3240
 atccggtccc aggttatgac acacctccgt gtgatttatg agcgcatgaa tcagtctctc   3300
 tccctgctct acaacgtgcc tgcagtggcc gaggagattc aggatgaagt tgcattcaaa   3360
 attaataaaa acatgaatta ttataaacca gatgcgggaa agatctctgg ctga         3414



      <210> 2419
      <211> 410
      <212> DNA
      <213> Homo sapiens


      <400> 2419
 cttcagctcc actttgaggt aaaatgccac cacatctcgc catgggttgt ccccccagac     60
 taaatccctg ggaacagcct gagctgggtg cacgcggccg aggcgacggc tgcccttgcc    120
 ctgcggagca cgggtgggca ttggatgtaa ggtattccta acttcccctt ccccagtcct    180
 tggcgtcctc tctagccatc ccaccccagg tcttctgcag cttcaccctg tcctccaagt    240
 cccctcgccc agctgcgagg caggagaccc cggccggagc tccgccagca ggtccttctt    300
 tcgcagggcg cagacgcacg attccgggat cgggtgcacc acggcgaagc ccaggcggga    360
 gacggcagga gcagctcagg taaccagggg aagcttgcgt gcccacggcc               410



      <210> 2420
      <211> 1208
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1208)
      <223> n = a,t,c or g


      <400> 2420
 tttttttttt ttgtgtgtat aaaaaagtga tatgtcttta atttaaaatt atgacccgga     60
 aataactagt cagtttaagt gatccagact tcctcttcat acccaaatgg aacagacaca    120
 atattggctc agatttccaa ccccagaaaa aaaccaaacc aagtcctcag gaagtccctg    180
 cagcgacctt gctggggcca tcagaccgca cagagtggag gtgcccaagc tgctaggctg    240
 ctcttaatcc agccacactg agaagagctt tccttctacc agcaactccc tcgctgggtc    300
 cgatatcccc cttcacctcc cttttagctg gcactgcacg aatgcctcca cagagaggct    360
 gacagtacag cagtcacctc ccagctgtct tcggtgcatc ttcagggcca ccttcctgtg    420
 gtcacaatag aggagttgag cattctaaac gttcgtgccc aggagggcag cgtcttctct    480
 ttttagctga ggtctggagc cctgagttgt aaccattggt catatgtggc tgaggcaccg    540
 acagcaaatc gccaaacttg ggaaacgatc tggggagatg caagggcctt ggtaattgat    600
 ggtgagtaag tccatggagt tttcatccca tcatggcaga aggctggcct gacccctgcc    660
 ctcactggat gatgctgtct ggctgcccat tctgggccac ctgcccaggg tcagaggcgg    720
 gggccgggtt agctgtgttg ctctgcaggt agcggcggaa atctttgatc ataggccgga    780
 ggacctggat gaggacgctc agggcagcct gtgtgccctc catggcctgg gcctggcgct    840
 cctgggcaca ggcctgcact tcctgggagc ggcggatcat ctgcagtagg tcgttctgct    900
 gttccaggtg ctgtgcgatc tccttcacat gcaggttggt gacccgctgc tcctgtatca    960
 gcttggcgga gttgagagca atgcggctct tgagcgcttg cggcttgacc gacgtgtctg   1020
 catgctgggc catcatgtcc acaggggtct ctggtggcag aggtgggggc gcctcagccg   1080
 tgcagtactc caccacgccc tcctccagcg tgtgataggt ggtctctgtg gggatctgtg   1140
 tcagggaatt ccacgcnntg tactgatgaa ttctatactc aattgnnnnn ggcccgcctc   1200
 ccttccct                                                            1208



      <210> 2421
      <211> 792
      <212> DNA
      <213> Homo sapiens


      <400> 2421
 tttcgtgagg acgtggagct gcccccgggg ggcttcgggg gcctgcaggc gctcaacccc     60
 aaccgcctct cagccatgcg ggaggccttc gccaggagcc gcagcatcag caccgacgtg    120
 tgacctgggc ccgcccccgg gatcctggcc ttgaaggtcc tgagacaatg gggggattcc    180
 tttggcacac ccacctggcc ccaggcccca agtggggctt ggctgagccc tcctggaatc    240
 cctgtcctca ggggaggccc aggcttgggg agcccccagg ctcgtggcag ggataaggct    300
 cattgaacac aaatgtgtcc tggggggagg cacagctggg gcctggggct agaaggacca    360
 ggtgaccata cagccggctg ggcatgcacc agggctctca ggcacagagg ccaccgttac    420
 tcctgatgat tctgtctcag acccaacaac ctggccttcc caggaggtct ccatgtgtca    480
 ccccctccct gggtctcacc cttctcacct gctcaaggaa gggatgacct cagtgaggcc    540
 cagggccctg cagcaaggcc ctccctggca attgcagacc aaggattctg ctcctccacc    600
 ttgaactcca gcctctttct ctccattttt ccctctctct cccctacccg tctctccctc    660
 tctctcacac acacactctt tccgggttca aggggccaag cgttttgcct agggttgagg    720
 acaagtggtt gaggttccct gaaggatggg accgggtttg ccccttagga aggggagatt    780
 tttcaagggg gc                                                        792



      <210> 2422
      <211> 1980
      <212> DNA
      <213> Homo sapiens


      <400> 2422
 tttttttttt tgagacagag ttttgctctt gttgcccagg ctggagtgca atggcgctat     60
 ctcacctcac tgcaacctct gcctcccggg ttcaagcaat tctcctgcct cggcctccca    120
 agtagctggg attacaggca tgcaccacca tgcccagcta attttgtatt cttagtagag    180
 acagggtttc tccatattgg tcaggcttgg tctcaaactc ccgatctcag gtgatctgcc    240
 cgcctcagcc tcccaaagtg ctgggattac aggcaagagc caccgcgccc agcacggtct    300
 tttcaaagac cagataattt atttaaccaa ctgtctaaag atggacattg tgattgatca    360
 cactatttta tatgtaacat tgaatggagt gggtgagtcc taggaaacat tctctcctaa    420
 aagtttacat ttttcattga ctagaagtga ccaaaataga ttctactgat gagaaaagac    480
 ttttgaaagc agtatggtca ggttggcagg tgaatggcct caagagctta ggatttcatt    540
 gctactaaaa gaacaagact attcagttgt gaaacaatga tttagtcaaa tactgatgct    600
 gtctcagatg agtaactgca aatcacttca aaaggtagaa gggtagctta aatgtgaaaa    660
 aggttactgc cacttcatgt agggaagata acaagcattt gcaaatagca aaatagaaag    720
 aaataaatgg tttcagtaca agctcttata ttcacttggc atcaaaatag tccaaaataa    780
 atctgagaac cacggcaagt tatagctgtg ttaatgacaa aatgtgatat ttactgttta    840
 aatttagcag ctgggagaat ccccttataa ggaagacaga aaatacattt atatccagac    900
 tgcattactc tttggaaaaa tatgaccaat cagattttgg gtattattgt tacaaccttt    960
 tccttcacct ctgcatcatg gtgatcaact aaagctctta ttttctgggc acattcttct   1020
 ccatgtaaca ggaaaaacaa tgaaccttca gtgaaagtag gctgcacagc taaatggcct   1080
 tctattttga ggcagttctt tatattctga aatagcgtaa gtactcgaag aagaatctcc   1140
 tttgctacgt ggctgtcata aagggaaagg aatgatgaat ccacttgggc acggagaagt   1200
 ccttctgtca tggctggatt ttcagacaaa ttcaaaagca gtttcaaaac ttgcaccttc   1260
 gtgtttccat ttccagtaag taacacctgg aacaggtctg taatgtaact gtgaagcatg   1320
 tgctggtggt cattggtaac agtcatgttt gtcaacaatg tcagtccagc cagctgcaca   1380
 gcagagttca gaggaccaga gaagacatcc tcacatactt gactgatgta tatctttatc   1440
 ttgatttgat tttcaacatt cacactcagg ttatttagtg catttaaagc tttctcttta   1500
 atactctggt tggaatggtt gattttgttt gcaacaattg gaataccacc caattcacga   1560
 ataatagctt ggttaactga aaaggctgca ttgttaccca aagtaatcaa agctctttca   1620
 ataattacag gatcctccgt tgactccagc aggtaaagga gtttctgaag ttgttcagca   1680
 tttagaacat catcatatga accatcagtt aagtcttctg cggacttcga agagcgtatc   1740
 ccgagctcgc ggtcgccccg ccgccgaccc cgggtcagcc tgtaaatgca gtagcaggcg   1800
 cccgcgccga gcagcaggcc cgccgccacc cagcccgcgc cccgggggcc acccatgctg   1860
 ccgccgcggc agagccgcag cgccgggcca gggcaggagg ctcgcggggg ccagcgcgga   1920
 ggtctccagc gcacgcgggc ctagccgcca cagcaaacgc cacctgacct ggctcgtgcc   1980



      <210> 2423
      <211> 531
      <212> DNA
      <213> Homo sapiens


      <400> 2423
 atggcaagga atgagtgtgt tgatgggcag cccggtcacc tagttgattt tacttgctta     60
 gtcacataca gagtttcagg agaatctagg gcaccccatc ccatggcaga gcttttcctg    120
 gtcatttatc acatggaaga gaagttggag acacacatac cccgcaagca agagagagtg    180
 gaggagaagg ggccatgcat ctgtaaggca ctgtccccaa attctgttaa tcagagagat    240
 gcaagagaga aagagatgtt gcagcagctg caaaacagag atacaaagca ggtgctgcct    300
 tccaaagctt ctgctcatac tccactggac aaagcacatc acacagctaa gcctgatggc    360
 agtggtggtg aaaaggattt tcttcacaca aggactaccc ccccgcccct gctccaggga    420
 agagcaggga atatttttaa caataaaaca gtctaccgta gcaacactat catcactata    480
 ggcagatggg tattgagggc cattgaactc aggcccaaag acaacaactg a             531



      <210> 2424
      <211> 2860
      <212> DNA
      <213> Homo sapiens


      <400> 2424
 atggcgcaac gccctatgag gaaactgagg ctcagggaaa gtaataacgg ccagggttcg     60
 cggcttgacg atccgatcga ggcgcaggcg ctgatcgcca cctacggccg tgatcgtgat    120
 cctggccggc cgttgtggtt ggggtcggtc aagtcgaaca tcggtcatac gcaagcggcg    180
 gcgggtgtgg ctggtgtgat caagatggtg atggcgatgc ggcacgggca gctgccacgc    240
 acgttgcacg tggaatcgcc gtcgccggag gtggattggt cggcggggac ggttcaactc    300
 cttacggaga acacgccctg gcccaggagt ggtcgtgttc gtcgggtggg ggtgtcgtcg    360
 ttcgggatca gtggtactaa cgcgcacgtc atcctcgaac agcccccggg agtgccgaga    420
 cccgctatgg caatccggga cagtttccct ctttgcccgc ctcctgctga ggccttcaac    480
 acctctggag gaagggctgc tacagtcaag tcttcaggag aaagcaagaa gggaccagtc    540
 tctacggatg tgcctagtca tccctcggta tccacagggg atgggttcca ggacctcatg    600
 ggtaccaaat ccaaggatgc caagttcctt cggcatattt tcgaacggtt gttgggtgaa    660
 tctgtggcta tcagagatgc cgagaaagca gggcgactac cgcacccgga tagtggaatt    720
 tcgagaccgg gttgaccaac cgggttgttt ctccatttgg ccaaattatt ctatatgcgt    780
 aatgtgtttg gtccgcgatt gccacgtgct aaagacgtat ttccaccggt gatcggggtt    840
 gctgcccata aaggtggcgt ttacaaaacc tcagtttctg gttcatcttg ctcaggatct    900
 ggctctgaag gggttacgtg ttttgctcgt gaaaggtaac gacccccaag gaaccagcct    960
 caatggtatc gcgggagggg gacccagctc ttcataatca gtgcagaaca cagctcttat   1020
 gcctctcata tcttgttgaa aaggacgatg tcacttatgc aataaagccc acttgctggc   1080
 cggggcttga ccattattcc ttcctgtctg gctctgcacc gtattgaaac tgagttaaat   1140
 gggcaaattt gatgaaggga aactgcccac cgatccacac ctgatgctcc gactggccat   1200
 tgaaactggg gctcatgctc atgactatga tgtcatagtt attgacagcg cgcctaacct   1260
 gggtatcggc acgattaatg tcgtatcgcc cccctgatgt gctgacccgt tcccacgcct   1320
 gttgagctat gtttgattac accttccgca ctggcagttt ttcgatatgc ttcgtgatct   1380
 gctcaagaac gcgtgatctt aaaaggggtc aaccctcgtg tccctttttt gctttaccca   1440
 atccagcaat agtaatggct ctcaattccc ggtggatgga ggagcaaatt cgggatgcct   1500
 ggggaagcat ggttctaaaa aatgttgtac gtgaaaccgg ttgaagttgg taaagggtca   1560
 gaatccggat gagaacctgt ttttgaacag gccattgatc aacgctcttc aactgatact   1620
 tcgttatcga caccagctgc cccgatggtg gattcgttaa ttgcgcgcgt aggagtaatg   1680
 gctcgcggta atgccattac tttgcctgta tgtggtcggg atgtgaagtt tactcttgaa   1740
 gtgctccggg gtgatagtgt tgagaagacc tctcgggtat ggtcaggtaa tgaacgtgac   1800
 caggagctgc ttactgagga cgcactggat gatctcatcc cttcttttct actgactggt   1860
 caacagacac cggcgttcgg tcgaagagta tctggtgtca tagaaattgc cgatgggagt   1920
 cgccgtcgta aagctgctgc acttaccgaa agtgattatc gtgttctggt tggcgagctg   1980
 gatgatgagc agatggctgc attatccaga ttgggtaacg attatcgccc aacaagtgct   2040
 tatgaacgtg gtcagcgtta tgcaagccga ttgcagaatg aatttgctgg aaatatttct   2100
 gcgctggctg atgcggaaaa tatttcacaa tgaatttgct ggaaatattt ctgcgctggc   2160
 tgatgcggaa aatatttcac gtaagattat tacccgctgt atcaacaccg ccaaattgcc   2220
 taaatcagtt gttgctcttt tttctcaccc cggtgaacta tctgcccggt caggtgatgc   2280
 acttcaaaaa gcctttacag ataaagagga attacttaag cagcaggcat ctaaccttca   2340
 tgagcagaaa aaagctgggg tgatatcccc acctgaagaa gttatcactc ttttaacttc   2400
 tgaaattaaa acgtcatctg catcaagaac tagtttaagc tcacgacatc agtttgctcc   2460
 tggagcgaca gtattgtata agggcgataa aatgtttatc acagttaaaa ttgctaaacg   2520
 cagtcaggca ccgtgtatga aatctaacaa tgcgctcatc gtcatcctcg gcaccgtcac   2580
 cctggatgct gtaggcatag gcttggttat gccggtactg ccgggcctct tgcgggatat   2640
 cgtccattcc gacagcatcg ccagtcacta tggcgtgctg ctagcgctat atgcgttgat   2700
 gcaatttcta tgcgcacccg ttctcggagc actgtccgac cgctttggcc gccgcccagt   2760
 cctgctcgct tcgctacttg gagccactat cgactacgcg atcatggcga ccacacccgt   2820
 cctgtggatc tacccactag tcaattcacc atcttgttga                         2860



      <210> 2425
      <211> 3630
      <212> DNA
      <213> Homo sapiens


      <400> 2425
 atttttcaca ttggccagtg taaactttta agtttacagg tgctttgtta tcttttctta     60
 cagggttacg actcactgat taaaaagagg gactttttca aatactttgc acttttgatt    120
 gtgtattatg gataccaagg aagagaagaa ggaacggaaa caaagttatt ttgctcgact    180
 gaaaaagaaa aaacaagcca aacaaaatgc agagacagcc tcagctgtag ctacaaggac    240
 tcatactggg aaggaagata ataatacagt agttttagag ccagacaagt gcaacattgc    300
 tgtgggaaga ggaatatatg actgatgaga aaaaaaagag aaaaagtaat cagttaaagg    360
 agatcaggcg tacagaacta aagagatatt atagtattgt agagttactg atggtcctgt    420
 gctgtcagcc tcctgaaccc ccttcagatg ctcttatgat agaaatagat ggaggagaga    480
 gctggtcgtt catggatgac aatcaaaaca aaacacatga taaaaaagag aagaagatgg    540
 tggttcagaa gccccatggg actatggaat acactgctgg aaaccaggac accctaaact    600
 ccatagcact gaaatttaac atcactccca ataaattggt ggaactgaat aaacttttca    660
 cacatactat tgttccaggc caggtccttt ttgtgccaga tgccaactct ccttccagta    720
 ccttaaggct atcatcatcc agtcctggtg ctactgtctc tccttcatca tcagatgcag    780
 aatatgataa attgcctgat gctgacttag cacgaaaggc cttgaaaccc attgaaagag    840
 tcttatcgtc tacttctgaa gaagatgagc caggtgtggt gaaattttta aaaatgaatt    900
 gtcgatactt caccgatgga aagggtgtgg ttggcggtgt tatgatagtg actcctaaca    960
 acatcatgtt tgaccctcat aaatctgatc ctctggttat tgaaaatggg tgtgaggagt   1020
 atggtctcat ctgccccatg gaagaggttg tttccattgc gctctacaat gacatttctc   1080
 acatgaagat caaagatgcc ttgccatcgc ctggagaatg ggaagacctg gcttcagaaa   1140
 aggatatcaa cccattcagt aagttcaaat ctatcaacaa ggaaaaacga cagcagaatg   1200
 gagagaaaat tatgacttcg gattccagac caatagtacc tttggagaag tccacaggac   1260
 atacacctac aaagccctca ggcagctctg tgtcagagaa attaaagaaa ctggactcct   1320
 ctagggagac atcccatggt tctcccacag tgactaagct cagcaaggaa ccttccgaca   1380
 cttcttctgc atttgaatct acagccaaag aaaactttct aggggaagat gatgattttg   1440
 ttgacttgga agaactttct tctcaaactg gtggtggaat gcacaaaaaa gacaccttga   1500
 aggagtgcct ttctcttgac ccagaggaac gaaagaaagc tgagtcacaa ataaacaatt   1560
 ctgccgtgga aatgcaggtg cagtcagccc tagccttttt gggaacagag aatgatgttg   1620
 aactgaaggg ggcgctagat ttagaaacct gtgagaagca agatataatg ccagaagtgg   1680
 acaagcagtc tggttcgcca gaaagccgag tagaaaacac actgaacata catgaagatt   1740
 tagataaagt taaactcatt gaatattacc tgactaagaa caaagaaggg ccacaggtat   1800
 ctgaaaattt gcagaaaaca gaattaagtg atggaaaaag tattgaacca gggggaatag   1860
 acattaccct tagtagttct ctttcccagg cgggtgatcc cataactgag ggcaataaag   1920
 agccagataa gacctgggtg aaaaagggag agcccctccc ggtaaaactg aactcttcta   1980
 cagaagcaaa tgtgattaaa gaggctctag actcctcttt ggaatctact ctggacaaca   2040
 gctgtcaagg tgcacaaatg gataataaat ctgaagttca gttgtggctg ttaaagagaa   2100
 ttcaggtacc cattgaagat atacttcctt caaaagaaga aaaaagcaag accccaccca   2160
 tgttcctgtg catcaaagtg ggaaaaccaa tgagaaaatc ctttgccact cacactgcag   2220
 ccatggtcca gcagtacggc aaacggagaa agcagccaga gtactggttt gctgttcctc   2280
 gggagagggt ggatcatttg tacacattct ttgttcagtg gtctcccgat gtctatggaa   2340
 aagatgccaa agagcaaggc tttgtggtgg tggagaagga agaactgaac atgattgaca   2400
 acttcttcag tgagccaaca accaagagct gggagatcat cactgttgaa gaggcaaagc   2460
 gcaggaagag cacatgcagc tactatgaag acgaggacga agaggtgctg cctgtcctac   2520
 ggccccacag cgcgctcctg gagaatatgc acatcgagca gctggcccga cgccttcctt   2580
 gcaagggtgc aagggtatcc atggagactg gcctatagca cgttagagca cgggaccagc   2640
 ttaaagacgc tctaccggaa atcggcatca ctagacagtc ctgtcctatt ggtcatcaaa   2700
 gatatggata atcagatttt tggagcatat gcaactcatc ctttcaagtt cagtgaccac   2760
 tattatggca caggcgaaac ttttctctac acattcagcc ctcattttaa ggtctttaag   2820
 tggagtggag aaaattcata ctttatcaat ggagacataa gttctttaga acttggtggt   2880
 ggagggggac gatttggttt atggctagat gctgatttat accacggacg aagcaactct   2940
 tgcagcactt tcaataatga tattctttcc aaaaaggaag acttcatagt tcaggatctg   3000
 gaggtgtggg catttgattg aaattcagac tgccttaaaa tataacatta aaaagactgg   3060
 gttcgatcag ccctcctaaa gctggctgga aaaagaagcc ccagcccagc ctgcctcatc   3120
 ccaccccaat gcttcctttc tgccatcatc tcagagcatg atcacattgc agaaagattc   3180
 tggaaggtcc atgtagaggg cagacattga agaaaagaaa cttaaaatcc aggttgttga   3240
 aaagactttg tactcccact tcctccaaat ccatacagtg aggaatcaga gtgtttatag   3300
 atatatgagt tgaatgcaat ttttattttt ggtaactgtg aaaaataaga tactgtggat   3360
 atatacatgc cttgtgtatt tatcagcata attttcatta ccaaaatgta cagctattat   3420
 ttgccatgga aaaggttagt ctcatttaga aaaatcgaaa gtgcacagca cttaaaggga   3480
 atatatgagg tttttttttt aaaaaaaaaa aacttttatt tattatttgt agtatattgt   3540
 ctgaaatgtg tcggcagttt tttttctttt aatgtgtcaa atcttgaaat attaaatgta   3600
 tacattttgt gctaaaaaaa aaaaaaaaaa                                    3630



      <210> 2426
      <211> 6517
      <212> DNA
      <213> Homo sapiens


      <400> 2426
 cctaaattag gttgtagttc accacttgta gaggcagctt caggccaaat ttaatttaat     60
 ttaataaact aatgaaataa ataagggaga gtctgattca gttgaattgt atttggagtt    120
 agaaatgttt attttaaagt tcaccagagg atttaaatat acactgaagt ttaagaatca    180
 ttgctgtaca aaggtgaaaa ataacatgct cttttaattt tgtagtctgt caagaactac    240
 accaaatgtc atgtgagaaa tgagcagatt tgtaacaaac ttaccagctg taaaagctgt    300
 tcactaaact tgaattgcca gtgggatcag agacagcaag aatgccaggc tttaccagct    360
 catctttgtg gagaaggatg gagtcatatt ggggatgctt gtcttagagt caattccagt    420
 agagaaaact atgacaatgc aaaactttat tgctataatc ttagtggaaa tcttgcttca    480
 ttaacaacct caaaagaagt agaatttgtt ctggatgaaa tacagaagta tacacaacag    540
 aaagtatcac cttgggtagg cttgcgcaag atcaatatat cctattgggg atgggaagac    600
 atgtctcctt ttacaaacac aacactacag tggcttcctg gcgaacccaa tgattctggg    660
 ttttgtgcat atctggaaag ggctgcagtg gcaggcttaa aagctaatcc ttgtacatct    720
 atggcaaatg gccttgtctg tgaaaaacct gttgttagtc caaatcaaaa tgcgaggccg    780
 tgcaaaaagc catgctctct gaggacatca tgttccaact gtacaagcaa tggcatggag    840
 tgtatgtggt gcagcagtac gaaacgatgt gttgactcta atgcctatat catctctttt    900
 ccatatggac aatgtctaga gtggcaaact gccacctgct cccctcaaaa ttgttctgga    960
 ttgagaacct gtggacagtg tttggaacag cctggatgtg gctggtgcaa tgatcctagt   1020
 aatacaggaa gaggacattg cattgaaggt tcttcacggg gaccaatgaa gcttattgga   1080
 atgcaccaca atgagatggt tcttgacacc aatctttgcc ccaaagaaaa gaactatgag   1140
 tggtccttta tccagtgtcc agcttgccag tgtaatggac atagcacttg catcaataat   1200
 aatgtgtgcg aacagtgtaa aaatctcacc acaggaaagc agtgtcaaga ttgtatgcca   1260
 ggttattatg gagatccaac caatggtgga cagtgcacag cttgtacatg cagtggccat   1320
 gcaaatatct gtcatctgca cacaggaaaa tgtttctgca caactaaagg aataaaaggt   1380
 gaccaatgcc aattatgtga ctctgaaaat cgctatgttg gtaatccact tagaggaaca   1440
 tgttattaca gccttttgat tgattatcaa tttaccttca gcttattaca ggaagatgat   1500
 cgccaccata ctgccataaa ctttatagca aacccagaac agtcgaacaa aaatctggat   1560
 atatcaatta atgcatcaaa caactttaat ctcaacatta cgtggtctgt cggttcaaca   1620
 gctggaacaa tatctgggga agagacttct atagtttcca agaataatat aaaggaatac   1680
 agagatagtt tttcctatga aaaatttaac tttagaagca atcctaacat tacattctat   1740
 gtgtacgtca gcaacttttc ctggcctatt aaaatacaga ttgcattctc acaacacaat   1800
 acaatcatgg accttgtgca gttttttgtc accttcttca gttgtttcct atccttattg   1860
 ctggtggctg ctgtggtatg gaagatcaaa caaacttgtt gggcttctcg acggagagag   1920
 caactgcttc gagaacgaca gcagatggcc agccgtccct ttgcttctgt tgatgtagct   1980
 ctggaagtgg gagctgaaca aacagagttt ctgcgagggc cattagaggg ggcacccaag   2040
 ccaattgcca ttgaaccatg tgctgggaac agagctgctg ttctgactgt gtttctttgt   2100
 ctaccacgag gatcatcagg tgcccctccc cctgggcagt caggccttgc aattgccagt   2160
 gccctaatag atatttcaca acagaaagct tcagatagta aagataagac ttctggagtc   2220
 cggaatcgaa aacacctttc aacacgtcaa ggaacttgtg tctgagaaat ggaaaccgct   2280
 cctgtatatt ctgtactgtt ttacttcggg cttctgttaa agctgttcta tggccttgga   2340
 ttttatggag gcagatctct gtatcatcca gagcctgagt acagtttcct tccaaatgga   2400
 caatgaccca ggtggccaaa gaatgttcat gagttttata aaagtattga tggtcacagg   2460
 tgataaagtc agtttttacc actatcttag gcttattata gctaacatta aattactctg   2520
 gaaaaagatg tatattgttt cttaatgaag atgaaaaata tgtaattcat ataaatcaac   2580
 tgtttatatc ccaagacttt aaagaaagac attttttaat gcctgaatga tgagaattgt   2640
 acagtttttg cctcataagc aaacttgaat cacctgtgta tgaacaggga atgaacacat   2700
 tgcaatggct ttaaatgctc ttttatctcg ttgtaaaggt aaggcaagat tttgatgtag   2760
 taggatgtag gtaatgtatt taaatatttc atatgaccat atcgtgtcca aactcagtct   2820
 gaggaatgtg acagctttcc gcctaactag gaatgcagac caggaatgag ttccaactca   2880
 ttctgtggca actttcacag gggggtttta tttggaatgc tcagtgtaga ggacattcct   2940
 gtcatccatg ccaactacct aactcgttat tcagagctga taggagcatg ggaaaagtct   3000
 gtccagcgat cagttgttcc cctccttcca aaaacagcct ccaataccac aacctgaaaa   3060
 gagccgaaat ggttatttta cagcatacaa gcttctgctc cagtatgata atttttaatt   3120
 gcctaagaat cattggatca gacctaaatg atccatctgc atttttataa gaatggatct   3180
 ttctttgccc ttcctctcct agctgctaga ttttaactac cttttacaaa tgttacaaaa   3240
 tgtattttag aggcgacatc tctcaagatg acctgagttc cttcctgcca actgttccac   3300
 ctagaataca agtagagaag agcactggct ggcaagcatc aacaggagtc ttcttcccaa   3360
 cacgagcgca tccatgtcct gagaaaaagt ctgtggttta gaaaatatgt ccatggttgc   3420
 ccacagtcag cacactctta gtgactcaaa attctgaatt atggcagaaa ggaaaaataa   3480
 aacatacttc acattagaac acagaatcat ttacatccta atactgacca cagttcacta   3540
 aagctcagta gcattaacag atatagtttg gaattgcagt ttcctcactt cagggtgaca   3600
 agatatgtat aacagtgaca gaaatctcca aagctgctgg tatatggata tagctttgtt   3660
 aaatatggaa ggtcctttaa atacaattga tgtttagtac ctataatatg tacttttcca   3720
 tattcctttg gatttctgga aggttatgga cactttacct gtttaacagc taatgccata   3780
 gttacttgca tgcccatggt tgtacagtag cagactatga ccctattgtg atattaagtg   3840
 tttatttcat aatgccattt atacatagct gaatttggat gaggattgga atgtccatat   3900
 ataagaggaa atgatccata caatatgtag ttgccatcct taatgtaaga tttcctaggt   3960
 tgccatccta acccatgact atgtcattat tttgataatt aggcatttat gaattatagt   4020
 atatattcct catgttggca tgataatttt gctattttcc atgcattaaa aataagacaa   4080
 attccttaga gtaattttag taattttatc tataatctgt ggggtttttt tggaggggga   4140
 ggccactggt tgtttctact tccctgtgat attttctctc tcattaaagg aatgagctaa   4200
 gtttgtaaat atctcctaaa aacaatcaag taattttatt agcttctttt ggaccctcta   4260
 aatattgact tctctcatga aaaaataaat tgatgaaact aatgattaca aagatataat   4320
 cattttttaa aaagtgattg cccaatgtat ttctctaaca attgtcacaa gagaaagcat   4380
 aacaataaaa atacaaaaac atacagattt agatgtaaaa tctatataag ctatattttt   4440
 agggaggcta agcagatagt attactgtgg aagaattatc aagttttatt cacctcaaat   4500
 cccactgggt tcttaaaact tgaaaattca aattgtagag aattatgaga cacaatgtga   4560
 tgtttagtta aagtcatgct atacctttct gggccacata ttgctaactc tgtggctaat   4620
 tatgcaatta attctcaacg tatcaaagct tttcactggc agtaaattct ttgccctcag   4680
 gtgaagtgga ttgaaaagac atcaaggatc aaggataatc actttgaatc tgttggtttt   4740
 tccccctaca ttccagacac tttaaatttg gatgctttca ttttttttaa atcaaaccac   4800
 acaaatatgc agatactttc ccagaatttc gcagttaaat ggctgatcct cttgaaaact   4860
 aaccttaatg gaattctaaa catttcagtt tagaatgact ttgaaaaatt ccttagattt   4920
 ttaggatgtt ttattctgcc aagtatgaaa aaaaaatggt taaatacaat ggagttttaa   4980
 aaattaacct ggggattcta tttgaactag aaaattccta ttggaaaaga atttgcacat   5040
 acttacagat tcagctaata aattttaaga ggattaggat tctcataatt ctttaaatga   5100
 aaatttgttt tagtgataca cagagatgcc gtatactata gtgttatgtt cagtaggaaa   5160
 acttcaaata gttcgtattt aaaaaggtaa ttgatccttg ctgtacttcc caacatctca   5220
 tcttctttta gctgcagcaa gatagaggtg actgtatggc tacagttcat ggtataagag   5280
 catttagggt gcacactggc acacaggctg gaaaacgggc actggaccca gctttcaggt   5340
 gtgtggtgct gggtaagttt cacctttgaa gcctcagcct tccatctgta aagggcggta   5400
 atggtgccca cctttcgagg cattgcgagg ctagatggta acacacagaa agctcccaca   5460
 gtgggacctt gatgcagcgt agctggtatt aacaaccgtg gggacaccag gccactcttt   5520
 ttctaccagt tgttttatga atccacctat taattttcat ccatcttttg gtcgtaggta   5580
 aaggtcaatc aggtttttca aaaagactcc ctgaataact taagttcctg tatttctaag   5640
 atatagggat ttctacaaaa cgactttgac atttagtcaa taaagactta aactcttctt   5700
 aaatctatag ttttaggaga gtttttctta aaattactga ctgatgacat tgagacaaga   5760
 gcatcaatga tcacctttca cgtacaaact aggcaagaca gggtcagtgc ttacattttg   5820
 tggttataca tgatacatct tttctcagtg aacataaaac tatgatttga aaggtgtctt   5880
 atatttaaaa aagattgtaa aatgaaaact gaccaaatga actaattcta cccacctatg   5940
 gtctttttaa atgtcgagtt tcaaaaccca tttgccgtat actagagtga gcttggaaac   6000
 ttacctgatt acaggaattg cttgggttca ggcagattcc cactttcacc tctagagatt   6060
 tagattcaga aacactgggg taggccctgg agagcagtac tcttaacaag ctcctcagtg   6120
 cttcttacca ttaggcaaat tagggaaaca ctgcattggg tcaaagtgct gcctttaatc   6180
 gaccattaga gggagttctc taaataacaa agttattact ctaattcaaa atgctttaaa   6240
 gaattttcca aggaatacaa gccatctggt tggtgttagt tatagcagtg atttcattag   6300
 agtgtacatt taacatttta gttttatcaa aattttttga aattaagaat tagaaccaga   6360
 gctcctatca gtatatatgt acacaggtgt gcatgccagt gttcaaaaca gattgtgtaa   6420
 aagttcaagc ccgttttaga aagccaacat tttatgttat aatatgctgt taatcaggac   6480
 tttattaaat aaaaacattg gctcttccaa cccccac                            6517



      <210> 2427
      <211> 1134
      <212> DNA
      <213> Homo sapiens


      <400> 2427
 atgaaggtga catttgcaaa caaacctgaa ggaggtggaa gactggccaa gcagagacct     60
 ccgggaagag gggctaggcc cagacccaag catgagggtg gccagagtgt tctgggaaca    120
 cgaagaccag cgctgctgca ggtgagctgc accgacgtga gcctgtcgga gcaggacaaa    180
 gacggcgcca ccgccacgca cttcgcggcg agccgcggcc acagcaaggt gctcagctgg    240
 ctgctgctgc acggcgggga gatctcggct gacctgtggg gcgggaccgc gctgtacgac    300
 gccgccgaga acggggagct agggtgctgc cagatcctgg tagtgaacgg cgcggagctg    360
 gaagtccgcg accgcgacgg gtacgcggcc gctgacctgt cggacttcaa cggccacagc    420
 cactgcaccc actgcctgcg cacggtggag aacctgcaca gggggatggt cctggctctg    480
 ggggctgcag aacacagcaa ggcccagagg ccagaggctg caggcgggcc tgagggtgaa    540
 cttccccccg agaaagagtc tctggaagag aatgaatggc ccagcagggg tcagggcttg    600
 gtgccctcag cacccactgc tgttgcccag agcatggagc actgcgtgct ctcccgggat    660
 ccatccgtgg agctggaggc gaagcagccg gattcaggca tgtcctcacc caacaccacg    720
 gtgtcggtcc agcctctgaa ctttgacctc agctcgccca ccagcaccct ctccaactac    780
 gactcctgct cctccagcca ctccagcatc aagggccagc accctccacg tgctcccaat    840
 ccccagattc tccagtacaa gaagaggttc tcggagctgg agcagctgtt ggagagatcc    900
 ggagagctgg agcagcagca gctgagggac gcagagcaca gccaagacct ggagagtgcc    960
 ctcatctggc tggaggagga gcagcaggga gggccagggc tcgcagcatg gccccctggg   1020
 cgagcgccta ctgatcccct gtgccccatt caggagtgcc agcctggccc aggtgaatgc   1080
 catgctctga gaacagctgg accaggcagg tttggccagc caggctctga gtga         1134



      <210> 2428
      <211> 416
      <212> DNA
      <213> Homo sapiens


      <400> 2428
 tttcgtacag atgctcgggt agccatcacc atctattacc aggccacgga agagttccag     60
 aatggtattg ccagctacat tcccaaagac aacagcctcc agtcggagac tgtgcagtac    120
 aagcgaggag tgtgtcagca gttctgcctg ccctcccaca ccgtggatcc ctccgagtgg    180
 gccgaagagg agcttggctt tgatttagac cgagaagttt accctctagt ggtacatgcc    240
 gtggtggatg aaggagacga gtattttggc cattgccatg tactgctggg tacttttgag    300
 aagcacacag atggaacttt ctgtgtcaag cccctcaaac agaaacaagt agtagacggg    360
 gtcagctacc tccttcagga gatctatgga attgaaaaca agtacaacac acaaga        416



      <210> 2429
      <211> 419
      <212> DNA
      <213> Homo sapiens


      <400> 2429
 tttcgtctcg gcggctctga cgggtccgtt ccggcgtgag gcgcagggac ccgcgtctcc     60
 gctcctgtgg gaggcccggg gctcgcagcg cgttcgggtg ccagggacgg tgggtgtatg    120
 gggtctgggc tggcgctgtg ctcttcgaga gggaccctaa gctgttccag ggctgggaga    180
 gatggcgaaa agagaattcg ccctttggag ccggaatgac tttggacaac tgcaagctct    240
 tttctgtcca actgcatttt agttataccc aaggagtgga aaagtaaatt attcggataa    300
 tgcagtttag ccactttcga acaaaatcgc aggttaacct gaatatccac atttttgaga    360
 aagactgtgt gggctttggg acgggtggca ggaggaaacg gcgcgcactt aaagtattt     419



      <210> 2430
      <211> 548
      <212> DNA
      <213> Homo sapiens


      <400> 2430
 ggcccgcccg cgcgtggtgc tcaagcgcct cggctcgcag cgcgagctgg cgcagctcgg     60
 accagagcat ctgcaagcgg gccaccggcc ggccccgctg cgacctgctg caggccatgc    120
 cccggaccga gttcgcgcgc ctcaacggcg acgtgcgtct gctcacgccc gaggcagtgg    180
 agggctggtc ggacctggtg cactgcccct cgcagcgcct tctcgaccgc ctggtgcgcc    240
 gctacgcgga gaccaaggac tcgggcagct tcctgcttcg caacctcaag gactcggagc    300
 gcatgcagct gctgctgacc ctggccttca accccgagcc gctggtgcta cagagttttc    360
 cgtctgatga aggttggcca tttgcaaagt atcttggagc ttgtggaaga atggtggctg    420
 taaattatgt tggagaagaa ctgtggagtt actttaatgc gccatgggaa aaacgagttg    480
 acctcgcttg gcaattaatg gaaatagcag aacagcttac aaacaatgac tgtgaatttg    540
 cactctac                                                             548



      <210> 2431
      <211> 1927
      <212> DNA
      <213> Homo sapiens


      <400> 2431
 cacggcaaga aaataataca cgaggggtcc cttcactgct gaagagcttc ctccaggagc     60
 gactgggaat ccacttaatt cgaaggaaga tagtaaagcc taagcatcat gttttgatgt    120
 ctcggaagga atcatggaag gtgaaaagcg aaatcccaaa ggtgccgaag cagcctctgg    180
 tgctccatca cccgcgcatg acgacaacca agtctccctc aaaggatatg ctagagccag    240
 aggcagagct ggctgaagat ctgcccacta ccaaaagcac ttctgtggag tcagagatgc    300
 ccactgagaa cctggaaggc cattccccgt cttgccggac cttcgtgcca ctgcctccca    360
 tctgctccaa ctccactgtg catagtgaag agaccctgtc ccacctgagt gacacaactg    420
 tccgcctcag cccagagcgc ccatcagatg aggactccaa gagcacagag tccatcttcc    480
 tgacccaggt gagtgaactg ccttcctccg tcatccataa ggatgattta gagttaaagg    540
 agaaagacca aaagaaacca ccaacggcac ccagagaggt gaaagggact cggaggaaac    600
 tcccaactgc cttccttccc agcaagtacc acggctatga agaactgctg acagccaagc    660
 ctgatccagc cttcattgag ccaaagggaa tccagaagaa tgcacaagcc ctgcaacaaa    720
 tgctgaagca cccactcctg tgccactcct ccaagcccaa gctggacact cttcagaaac    780
 cctatgttca caaagagaaa cgggcccaga gaatcccgat tccaccccca aagaagacta    840
 gagcccaact tctggatgac atcttcattc gcttgcggga tccccggaac attacagagg    900
 ctccactagg tgctgtcctg caccagtgga cagaacggcg gctggtgaac cacaagcagt    960
 acctggaggc caagaggctg ttgaaggagt tccaggcacg ttaccggcag ctggtgagtg   1020
 gctctctgcg cacagtgttc gggactaccc cgctccccat ggcctgccca gcgctgagtg   1080
 agagccagcc caagttcggc cacttcctcg agttcatgga tgagttctgc caggagccca   1140
 cagccagtga ctcacaaggc tagagctgtg catgggggct gtgtgcacca cccggcctgt   1200
 gccccagctc tccccgaggg ctctgtgccc tggaccgcac ctcaaggttg accagccggc   1260
 cacaggcctc agagctcagc tgggccccac ttgctggcca caaggtggca tccccttgtc   1320
 aggatctccc ctccttggcc caggcatgac ctggtgcctg gcccagcggc aataaagagt   1380
 gggtgcacag ggcaatagac tgggtgccac atgcattctt tcttggaacc caggccacag   1440
 cagcattgtc acacttccct ctaaaaatgg ttttccagtt cagatgcaac agggatacat   1500
 ttgttctctg ttgtatgaga aactgacacc aaggggatct taacaaattc ctgaacaatg   1560
 gctccaaaaa agggtatttt taaaaaccag atcttgtgag tacagcccta atgtgcaggg   1620
 acagtgtcat cctgtatatt cgttctttac tcagactctt tcttggttcc ttcattagga   1680
 gcatgaatgg ttgaatgtga acatgacagt aaattggagc aaactgtaaa ctggacataa   1740
 cttatgccaa aagacgtagt tgtacaccat ggaaacccca tccctgctcc taatctctac   1800
 tgccattctg aatgccaaag caagacatcc aacatggggc atctcccaga gcacatacag   1860
 caccaaaaat ccacacacag cctaagctta acccatgttt ttgtcttgag attgttcacc   1920
 agagaca                                                             1927



      <210> 2432
      <211> 1818
      <212> DNA
      <213> Homo sapiens


      <400> 2432
 gaaatatcag catctggggt cctggcaagc aaggaagctt ccaagtaaaa accagagaga     60
 agggcacact tttctttctt cattaggaaa tcttattgca caggaaccac ccccaccccc    120
 accccccaca ccttcccaag gcagcatccc agtgcagata gagtgggaaa ggtcccagaa    180
 gggggctcac tcacctctag gcccagagag gctttctcct cactttatac actgcaaaaa    240
 cagaagaatt gtgtcaataa caccctctgt agtggagaaa cttaaaaagc tggttaggaa    300
 gctctcgtgt atatttagag acaattacaa gaaagctgga cttgccgctg tggtctcagg    360
 agaaatgagt gttcttgatg acaggcaaag ggacatctta gttgtccaga agcggcactc    420
 ttccctggaa gccgccatgt taataggatt actagcctgg ctccagacag tgcctgctca    480
 tggctgccag ttcttaccga tcacatctgt cactgccacc gtatatcatc tgccagtgca    540
 tcagcttaag gggaggtcac gagtgcaaaa gaacctgacc cttgacaatg agggagaagg    600
 gacatggacc acctgtctgg aattcctgga atcactggca gggtggaggc tgggctgggg    660
 agttagccgc ggtgtgcgtg aatggctctg tctccagcaa gtctctctcc atcaaacccc    720
 aggtctgccc cataagcaag atctttaaca gatggatgtc tccatgagaa aacccaaggc    780
 gagaagccca gagccatggc ggggttgctt gacgtcctca tggagtcact ctgccccaca    840
 tgctcaaatc ttccctctgg ccccacatcc ctaggagggc ctgacccctg taaagataca    900
 ggaggcagct ccctggcctc caaatggccc atggagatgg cagtcgggag acagggttct    960
 gtgtttgctg cggtgaaggg aggagaaggc aggaggaaaa aggatggctt ctagccctga   1020
 agaggactcc agcatcccag gcaccgggtg cttctggctg cagttttccc tatggaggcc   1080
 cctcagcctc cagccctaac ataaatgtcg gttaaattca gttttcaagc ctctctccct   1140
 tttcagtgtc agagcagtag atggtccagg gcattggagg cctcgaccac tctgcattgc   1200
 agattacagt gacttcctcg gggttgcccc atcttggtct cctgtggttt cttcatcagc   1260
 ttttttttta ccagcatctc tcaaataaca atgaagatag atatgcccat tagtgtctga   1320
 ttaaggagca aaggctggat ttctggccac agcgagctgc actctccctc ctgcctcagc   1380
 cggggtccgt cttagcagtt tggaaagggg aaaaagatgc cggtcctcac tgcttaagtt   1440
 ttgtgtccag gtgccactag acttgcatgc acactaactc cttacaatca ccacacagca   1500
 tcatcgcccc agtgcacaga tgaggaacca gaggctcaga ggagtgaagt tgccttcctg   1560
 aggtcacaca gcatgaaagt gatgagctag gatttgaatc tgggaagttg ggctctagag   1620
 ccagactgta ctgccttctg ccacactgta ctgccttctg tgactgggtg gcacctccag   1680
 ggcacattta cacaaggccc tgaatctgca gaggctgttt ctcaagatgc ccgtcatggt   1740
 gtggcctggg ccagctctgg cttccacagg tccctgactg tcctcagagt ggaacatgct   1800
 caacctcccg cccactgc                                                 1818



      <210> 2433
      <211> 2397
      <212> DNA
      <213> Homo sapiens


      <400> 2433
 tgactctctt ttcggactca gcccacctgc acccaggtga aacaaacagc catgttgctc     60
 acacaaagcc tgtttggtgg tctcttcaca cggacgcgca tgaaatttag tggatcaggg    120
 gacctccctt aggagatcaa tcccctgtcc tcctgctctt tgctccgtga gaaagatcca    180
 cctatgacct caggtcctca gaccgacctg cccaagaaac atctcaccaa tttcaaatcc    240
 gagacaaagg agacacgttt tatctgtgga cccaaaactc cggcgccgct catggactag    300
 ggaaggcagc cttcccttgg tgtttaacct ttgcagggat gcctctctga ttattcaccc    360
 aggtttcaga ggtgtcagac cacgcaggga cacctgcctt ggtccttcac ccttagcagc    420
 aagtcccact tttctggggg aaggggcaag atttaattaa cctcgccttc aaggtgtaca    480
 ataatagaaa aaagttgcaa ttccttgcct ccactgtgag acaaacccca gccacatctc    540
 cagcacacaa gaacttccaa acgcctgaac tgtagcagcc agacgtttct ccagaacctc    600
 ctcccccagg aacttgctac acatgccgga aatctggcca ctgggccaag gaacgcccgc    660
 agcccgggat tcctcctaag ccgcgtccca tctgtgtggg accccactga aaatcggact    720
 gttcaactca cctggcagcc actcccagag cccctggaac tctggcccaa ggctctctga    780
 ctgactcctt cccagatctt ctcggcttag cggctgaagg ctgatgctgc ccgatcgcct    840
 cggaagcccc gtagaccatc acggatgccg agcttcgggt aactctcaca gtggaagaag    900
 gcaggaatgt caggcctctg agcccaaagc taagccatca tatcccctgt gacctgcaca    960
 tacacatcca gatggccggt tcctgcctta attgatgaca ttccaccaac aaaaggaagt   1020
 gtaaatggcc gggtccttgg ctttaagtgg atggaggtta ccttgtgaaa agtcctttac   1080
 ctggctcatc cctggctcaa aaaagctccc gccactgagc accttgtgac ccccattcct   1140
 gcccgccaga gaacaacccc catttgactg taattttcct ttacctaccc aaatcctata   1200
 aaacggcccc acccctatct cccttcgctg actctctttt cggactcagc ccgcctgcac   1260
 ccaggtgaaa taaacagcca tgttgctcac acaaagcctg tttggtggtc tcttcacacg   1320
 gacgcgcatg aaatttggtg ctgtgactcg aattggggga cctcccttgg gagatcaatc   1380
 cgctgtactc ctgttctttg ctccgtgaga aagatccacc tatgacctca ggtcctcaga   1440
 ccgaccagcc caaggaacat ctcaccaatt ttaaatcagc cccctggacc atcacggacg   1500
 ccgagcttcg ggtaactctc acagtggagg actcagccca cctgcaccca ggtgaaataa   1560
 acagctttat tgctcacacg aagcctgttt ggtggtctct tcacacggat gcgcatgaaa   1620
 tttggtgccg tgacttggat cgggggacct cccttaggag atcaatcccc tgtcctcctg   1680
 ctctttgctc cgtgagaaag atccacctac gacctcaggt cctcagaccg accagcccaa   1740
 gaaacatctc accaatttca aatccacctc ccttgtgttc tcctcttgta ttcccccacc   1800
 ttaaccctca agtatatctc tactccctcc ttggcgaccg atcatgcacc ccttaccatc   1860
 tcattaaaac ctaatcaccc ttaccctgct caatgccaat atcccatccc acagcatgct   1920
 ttgaaaggat taaagcctgc tatcactcgc ctgctacagc atggcctttt aaagcctata   1980
 aactctcctt acaattcccc cattttacct gtcctagaac cagagaagat ttacaggtta   2040
 gttcaggatc tgcgccttat caaccaaatt gttttgccta tccaccccgt ggtgccaaac   2100
 ccatatactc tcctatcctc aatacctccc tccacaatcc attattctgt tctggatctc   2160
 aaacgtgctt tctttactat tcctttgtac ccttcatccc agcctctctt cgctttcact   2220
 tggactgacc ctgacaccct tcaggctcag caaattacct gggctgtact gccgcaaagc   2280
 ttcacagaca gcccccatta cttcagtcaa gcccaaattt cttccttatc tgttacctat   2340
 ctcagcataa ttctcataaa aacacacacg ctctccctgc tgatcatgtc cgattaa      2397



      <210> 2434
      <211> 375
      <212> DNA
      <213> Homo sapiens


      <400> 2434
 atcccaaggc gacccggtgc cctggatggc ctggaagctg gtggctatgt ctcctccttt     60
 gtccctgcgt gctccctggt ggagtcgcac ctgtcggacc agctgaccct gcacgtggat    120
 gtggccggca acgtggtggg cgtgtcggtg gtgacgcacc ctgggggctg ccggggccat    180
 gaggtggagg acgtggacct ggagctgttc aacacctcgg tgcagctgca gccgcccacc    240
 acagccccag gccctgagac ggcggccttc attgagcgcc tggagatgga acaggcccag    300
 aaggccaaga acccccagga gcagaagtcc ttcttcgcca aatacagtct cgctctgtca    360
 tccaggctgg agtaa                                                     375



      <210> 2435
      <211> 1599
      <212> DNA
      <213> Homo sapiens


      <400> 2435
 gcggtggaat tcgtcattct taaggactgt tctgtcccca accccagctg gaacaaggac     60
 ctaagactgc tctttgacca gtttatgaag aaatgtgaag atggctcctg gaaacgtttg    120
 ccttcatata aacgtacacc tactgaatgg attcaagact tcaaaaccca ttttcttgac    180
 ccaaagctta tgaaagaaga acaaatgtca caggcccagc tcttcaccag aagctttgat    240
 gatggcctgg gctttgaata cgtgatgttc tacaatgaca ttgagaaaag gatggtttgc    300
 ttatttcaag gaggccctta cctggaagga ccacctggat tcattcatgg aggtgccatt    360
 gcaaccatga ttgatgctac tgttggtatg tgtgcaatga tggctggggg aatcgtcatg    420
 actgccaatc tcaacatcaa ttataaaaga cctatccctc tttgttctgt tgttatgata    480
 aatagccaac ttgataaagt tgaaggaagg aaattttttg tttcctgtaa tgttcagagt    540
 gttgatgaga agaccctata ctcagaggcg acaagcttat ttataaagct gaatcctgct    600
 aaaagtctga cataaagagc tgctggtgaa ctccatctca ttctcgcccc tccagaagaa    660
 gcagttgtcc cccaaatact ctgctccctc actgctgaat ccctgtaggg agaagcctgc    720
 caacagtgac cttccgaaac agccttctga atacaaagag gattcagttt ccatcttctc    780
 aactttttaa cacagaaaca cttcctgcga gcatatcgac aactctcggg ccaggcgctg    840
 tggctcacac ctataatccc agcactttag gaggccgagg caggcggatt gcctgagctc    900
 aggagttcaa gatcagtctg ggcaacacga tgaaactccg tctctactaa aatacaaaaa    960
 attatccagg catggtggcg tacgcctgta gtcccagcta ctcaggaggc tgaggcagga   1020
 gaattgcttg aacccaggag gaagaggttg cagtgagcca agatcatgcc acatcactcc   1080
 aacctgggca acagaacaag aacccatctc aaacaaacaa acaaacaaaa aaaaaaaaac   1140
 tcttgtctcc ttaggatatg ttacctgctc cactgcagac tagagaaata aatgtgtatt   1200
 gaacctttta ctgcaaactt gaaaatgcta gaaaaccaag catgaagaat aaatacatgg   1260
 cgggaaacac acaggcatgt gcatatgcat atacattgta agttagtaag ttagaaagct   1320
 agctttgttg tatctgaaca catgaatctt ttttggtcag tgtaggaagc acagccagat   1380
 cctataggaa tgaatacctc aaatctgttg tctgagattc tagagattaa accactgtgc   1440
 catttttaac ccaggctgta ctattgtttc ttaccaacag cataggtttt catcactgga   1500
 aggagcctgt gttcatttcc tagggctgct gtagcaaagt agtacaaact ggattgttta   1560
 aaccaacaaa aactcattgt ctctcagttc tggaggcca                          1599



      <210> 2436
      <211> 3543
      <212> DNA
      <213> Homo sapiens


      <400> 2436
 cggcaaaact tttttttctt tgtctttttt tttcttttag gtaaattaat gtttattcat     60
 aacgattttt aatgttattt gttattctaa aacttgcaaa aattccatct gttataggag    120
 ttattgaaat agtcatagat gggtgtatgt gcgggcgaga agatggcggc ggcgggggaa    180
 gcagcgtgag cagccggagg atcgcggagt cccaatgaaa cgggcagcca tggccctcca    240
 cagcccgcag tatatttttg gagattttag ccctgatgaa ttcaatcaat tctttgtgac    300
 tcctcgatct tcagttgagc ttcctccata cagtggaaca gttctgtgtg gcacacaggc    360
 tgtggataaa ctacctgatg gacaagaata tcagagaatt gagtttggtg tcgatgaagt    420
 cattgaaccc agtgacactt tgccgagaac ccccagctac agtatttcaa gcacactgaa    480
 ccctcaggcc cctgaattta ttctcggttg tacagcttcc aaaataaccc ctgatggtat    540
 cactaaagaa gcaagctatg gctccatcga ctgccagtac ccaggctctg ccctcgcttt    600
 ggatggaagt tctaatgtgg aggcggaagt tttggaaaat gatggtgtct caggtggtct    660
 tggacaaagg gagcgtaaaa agaaaaaaaa gcggccacct ggatattaca gctatttgaa    720
 agatggtggc gatgatagta tctccacaga agccctggtc aatggccatg ccaattcagc    780
 agtcccgaac agtgtcagtg cagaggatgc agaatttatg ggtgacatgc ccccgtcagt    840
 tacgcccagg acttgtaaca gcccccagaa ctccacagac tctgtcagtg acattgtgcc    900
 tgacagtcct ttccccggag cactcggcag tgacaccagg actgcagggc agccagaggg    960
 gggccccggg gctgattttg gtcagtcctg cttccctgca gaggctggca gagacaccct   1020
 gtcaaggaca gctggggctc agccctgcgt tggtaccgat actactgaaa accttggagt   1080
 tgctaatgga caaatacttg aatcctcggg tgagggcaca gctaccaacg gggtggagtt   1140
 gcacaccacg gaaagcatag acttggaccc aaccaaaccc gagagtgcat cacctcctgc   1200
 tgacggcacg ggctctgcat caggcaccct tcctgtcagc cagcccaagt cctgggccag   1260
 cctctttcat gattctaagc cctcttcctc ctcgccggtg gcctatgtgg aaactaagta   1320
 ttcccctccc gccatatctc ccctggtttc tgaaaagcag gttgaagtca aagaagggct   1380
 tgttccggtg tcagaggatc ctgtagccat aaagattgca gagttgctgg agaatgtaac   1440
 cctaatccat aaaccagtgt cgttgcaacc ccgtgggctg atcaataaag ggaactggtg   1500
 ctacattaat gctacactgc aggcattggt tgcttgcccg ccgatgtacc acctgatgaa   1560
 gttcattcct ctgtattcca aagtgcaaag gccttgtacg tcaacaccca tgatagacag   1620
 ctttgttcgg ctaatgaatg agttcactaa tatgccagta cctccaaaac cccgacaagc   1680
 tcttggagat aaaatcgtga gggatattcg ccctggagct gcctttgagc ccacatatat   1740
 ttacagactc ctgacagtta acaagtcaag cctgtctgaa aagggtcgac aagaagatgc   1800
 tgaggaatac ttaggcttca ttctaaatgg acttcatgag gaaatgttga acctaaagaa   1860
 gcttctctca ccaagtaatg aaaaacttac gatttccaac ggccccaaaa accactcggt   1920
 caatgaagaa gagcaggaag aacaaggtga aggaagcgag gatgaatggg aacaagtggg   1980
 cccccggaac aagacttccg tcacccgcca ggcggatttt gttcagactc caatcaccgg   2040
 catttttggt ggacacatca ggtctgtggt ttaccagcag agttcaaaag aatctgccac   2100
 tttgcagcca tttttcacgt tgcagttgga tatccagtca gacaagatac gcacagtcca   2160
 ggatgcactg gagagcttgg tggcaagaga atctgtccaa ggttatacca caaaaaccaa   2220
 acaagaggtt gagataagtc gaagagtgac tctggaaaaa ctccctcctg tcctcgtgct   2280
 gcacctgaaa cgattcgttt atgagaagac tggtgggtgc cagaagctta tcaaaaatat   2340
 tgaatatcct gtggacttgg aaattagtaa agaactgctt tctccagggg ttaaaaataa   2400
 gaattttaaa tgccaccgaa cctatcggct ctttgcagtg gtctaccatc acggcaacag   2460
 tgcgacgggc ggccattaca ctacagacgt cttccagatc ggtctgaatg gctggctgcg   2520
 catcgatgac cagacagtca aggtgatcaa ccagtaccag gtggtgaaac caactgctga   2580
 acgcacagcc tacctcctgt attaccgccg agtggacctg ctgtaaaccc tgtgtgcgct   2640
 gtgtgtgcgc ccagtgcccg cttcgtagga caccacctca cactcacttc ccgcctctct   2700
 ttagtggctc tttagagaga aactctttct ccctttgcaa aaatgggcta gaatgaaaag   2760
 gagatgcctt ggggttcgtg cacaacacag cttctgttga ctctaacttc caaatcaaaa   2820
 tcatttggtt gaaacagact gttgcttgat tttagaaaat acacaaaaac ccatatttct   2880
 gaaataatgc tgattcctga gataagaaag tggatttgat ccccagtctc attgcttagt   2940
 agaataaatc ctgcaccagc aacaacactt gtaaatttgt gaaaatgaat tttatctttc   3000
 cttaaaaaag aaatttttta atccatcaca cttttcttcc ctacccttta gtttttgata   3060
 aatgataaaa atgagccagt tatcaaagaa gaactagttc ttacttcaaa agaaaaataa   3120
 acataaaaaa taagttgctg gttcctaaca ggaaaaattt taataattgt actgagagaa   3180
 actgcttacg tacacattgc agatcaaata tttggagtta aaatgttagt ctacatagat   3240
 gggtgattgt aactttattg ccattaaaag atttcaaatt gcattcatgc ttctgtgtac   3300
 acataatgaa aaatgggcaa ataatgaaga tctctccttt cagtctgctc tgtttaattc   3360
 ttgctgtctg ctcttctcat aatgctgcgt ccctaattgt acacagttta gtgatatcta   3420
 ggaggtataa agttgtcgcc catcaataaa ctgtgtacaa ttagggacgc agtttagtga   3480
 tatctaggag tataaagttg tcgcccatca ataaaaatca caaagttggt ttaaaaaaaa   3540
 aaa                                                                 3543



      <210> 2437
      <211> 1669
      <212> DNA
      <213> Homo sapiens


      <400> 2437
 gcgaccacag ggctgaggtc agggctagga ttccggtgtc tctacgtagg ttgcttgaat     60
 ggggggcacc ctggcatgga cgctgctgtt gccgctgctg ctgcgggagt cagacagcct    120
 agaaccgtcg tgcaccgtgt cctccgcgga tgtggactgg aacgcggagt tcagtgccac    180
 gtgcctgaat ttcagtggcc tcagcctgag cctgcctcac aaccagtctc tgcgggccag    240
 caacgtgatt ctccttgacc tgtctgggaa cggcctgcga gagcttccag tgaccttctt    300
 tgcccacctg cagaagcttg aggtcctgaa cgtgctacgc aaccccttgt ctcgtgtgga    360
 tggggcgctg gccgcccgct gtgaccttga cctgcaggcc gactgcaact gtgccctgga    420
 gtcctggcac gacatccgcc gagacaactg ctctggccag aagcctctgc tctgctggga    480
 cacaaccagc tcccagcaca acctctctgc cttcctggag gtcagctgcg cccctggcct    540
 ggcctctgca actatcgggg cagtggtggt cagcgggtgc ctgcttcttg gacttgccat    600
 cgctggccct gtgctggcct ggagactctg gcgatgccga gtggccagaa gccgggagct    660
 gaacaaaccc tgggctgctc aggatgggcc caagcccggt ttaggcttgc agccacggta    720
 cggcagccgg agcgccccca agccccaagt ggccgtgcca tcctgcccct ccactcccga    780
 ctatgagaac atgtttgtgg gccagccagc agccgagcac cagtgggatg aacaaggggc    840
 tcacccttca gaggacaatg acttttacat caactacaag gacatcgacc tggcttccca    900
 gcctgtctac tgtaacctgc agtcactggg ccaggcccca atggatgaag aggagtacgt    960
 gatccccggg cactgagcct aagatgtcct aacctccacc cagaacccct tcagtccctg   1020
 ctgggtgact cagggcgtcc taacgcctcc atggcctcag tttccccatc tgaagaatgg   1080
 gtacaggaaa ggattgtcct tgaggcccca ggaagctctg ccgccccctc cctgtccctc   1140
 atgccgctcc tcagctccct cagctcctag agggggaaga ggagagaccc ccaacaaggg   1200
 gacaggaggg tcactgtgcc aatcctgtca tcaccctcct gtggatgtac aggcagtgct   1260
 caataaatgc ttcgaggctg atgaggctgc tggctcaggg tgcgtgggtt cctcaaggtg   1320
 gggatttctg agttctaaga ccaagtctcc atctgagact cccaaattgc tccccacctc   1380
 ccatccctgt ttttttttgt tggtgggggt tgtttgtttg tttttgaaac tgagtctcac   1440
 tctgtcaccc aggtgggagg gcaaggttgg ggtttaagtt aattgaaacc tcggcttccg   1500
 gggttaaagg gattttccgg cctaaccctc cggagaagtg gggattacgg aacccgccac   1560
 catgccgggc taattttggt atttataaaa aaaagggggt ttcgccatgt gggccaggtt   1620
 ggtttcgaat tcttgaccta aagcgatttg cccgcctggg cctcctgaa               1669



      <210> 2438
      <211> 805
      <212> DNA
      <213> Homo sapiens


      <400> 2438
 tttttttttt ttaaaaacaa caacaaacca ctttaatgga cacataaaat ccctgggggt     60
 ctcattgcaa tgcagatttg gattaaacag tctgggtggg tcctgagacc ctgatcccct    120
 tgcttttcac ctatggccac attttgagaa gcaaggccac tcaaagggcc cccatctgtg    180
 tgaatcaacc cctgctccat ctgcccctat aaatgacagg agtgggggtg tccccaggtc    240
 tgagcctgga gggggttgca ggcttcctcc aggcatggaa gtggagtgag aggaggctgt    300
 agttaaacgg gttactctgt cagcagacac agaggagacc agaatagctt ttatttcaca    360
 tgaagctaag gaaggaagtc gagaggacag ggctggttct gtgggcgctg ccctggcagg    420
 tgcaccacct ccaactgctg ggctccagct ccagggctca gaagccatct ccgagaaggt    480
 cgggagcggg gctgaagggt cccgggggca ggttccaggc cagctcctcc agcaggccca    540
 gcaggccttt cacctctgtc cccaggtgat ccacggtctt ctctaccatc tcctccatga    600
 catctagacg gcgttgcaca gccatgtgtc tgtcacacgc tgtgctctga gctgagtctc    660
 ctcgcggagg gctgaagggt tcggcagcgg ccaaagagcc cgcggcgcgg agcagggcca    720
 gtccggtcag cgcgcagagc aggggccgca tggtgccggc ctggccgagc gcagcgccgc    780
 gtctgcccgc agccgccctt cccgg                                          805



      <210> 2439
      <211> 1202
      <212> DNA
      <213> Homo sapiens


      <400> 2439
 tggcggcggg tcggggcgag aggctgaggg gatctggcgg tggagcgcta ggatcagacg     60
 cccccgcgat gaccagctcc cccgtctcca gagtcgtgta caacggcaag aggaccagca    120
 gcccccgctc cccacccagc agcagcgaga tcttcacccc agcccacgag gagaacgtcc    180
 gcttcattta cgaagcctgg cagggtgtgg agcgagacct gcgaggccag gtgccgggtg    240
 gcgagcgggg cctggtggag gagtatgtgg agaaggtccc taaccccagc ctgaagacct    300
 tcaagcccat cgacctgagt gacctgaagc gccggagcac gcaggatgcc aagaagtcct    360
 agagcgcccg gtgcccctcc ccggcctccg gaagatcagg gtgcgaggtg tcggttccct    420
 cctgtcctgt ggtcctgccc ctgggatggg ggtgccttgc tccagcgggc tgcagatccc    480
 agcactggcg tgactgacgg ctgaggcctg cctctccttc ccaagccccc ttccttcatc    540
 cttgggggtc tcaggctgcc cccatcatgg gggtctgggc cctgcccacc ctcctgccct    600
 cccccagcca cctggctgca tttttgaagc tgcctggccc ccaggggccc tgacctgacc    660
 tctctcctct cccctcaccc tcctgcccct ggccactgca ggatcaggag gggagaagaa    720
 ggagcctctg ctgcctccca ggctgctggg actgggctgg ttttgtcctt gaagtggtca    780
 ggatacagga caagggcagc cccaccccat ccagcctggg ctccccgcag acccttgctg    840
 ctcccgtggc ctggacacgc tggggagctt ctcacaccta cccctaccgt ccagcctggc    900
 ctcttccctg aatcagcttc aagatggcac cagctctttg ggcctaggat actgccgggc    960
 cccccaaggg ggtccccagc aaccaggcct ggcctcctgg tgtctgcggt cacagtggcc   1020
 cctgggcagg ggcacccagg ctgaccctga ggtgctgctg ctgggtctgt cttggctctg   1080
 gggtgtgctg ggagggtcac caggtccctt ttccttcctg tgccctctga aagctaagtg   1140
 tctgtgtggc tgtggagctc gagggtctgt gaataaaggc ggcggcactg ggaaaaaaaa   1200
 aa                                                                  1202



      <210> 2440
      <211> 382
      <212> DNA
      <213> Homo sapiens


      <400> 2440
 gaggacgacg aggaggagac caccgcgtcc acgctgcggg gcaagcgcca ggccgccgcc     60
 cgtctcggcg cagtccgcct tcagctacat cccgccgcgg cgcctggacc ccacagagca    120
 cagctactac taccgcccgg cgcgggaaca ggagaggccg gctggagtgc tgacgtcttc    180
 tgtctatggg aagcgcatca atcagcccat tgagccccta aaccgggact ttggccgtgc    240
 caaccatgtg caggctgact tctacaggaa gaacgacatc cccagcctca aggaacccgg    300
 ctttgggcac attgctccat cctgaagcat acccgtggcc cacagggcat gtccgatacc    360
 ctgtggcctg gcaagtttgc ac                                             382



      <210> 2441
      <211> 3429
      <212> DNA
      <213> Homo sapiens


      <400> 2441
 atggctggag gccaggaagt ggaggctgtg gttgctgatc agctctgtgc caagtatagc     60
 aaggaatatg gcaagctatg taggaccaac cagattggaa ctgtgaatga caggctaatg    120
 cacaagctga gtgtggaagc cccacccaaa atcctggtgg agagatacct gattgaaatt    180
 gcaaagaatt acaacgtacc ctatgaacct gactctgtgg tcatggtaga agacatcctg    240
 gaaatgtcct tggtggagtt tgggaatatc ggggaagcat ttctagagca gaaccagtct    300
 cccgagtctt cagtgacttt gacctctgcc aatgctactc tgctgctgag cagacaaaac    360
 atatcaactt taccgctgag ctcttacact ctgggtcacc cagcccctgt gaggctaggc    420
 tttccgtcgg ctttagcttt gaaggagctc ttgaataaac atccaggagt taatgtccaa    480
 gttttcgctt tagacccagt cctgggcacc tttctgatcc tcaccagtgt catcttgatg    540
 gtacttgtgg taattaatct tttcgtttcg gccattctca tggcctttgg aaaagaaaga    600
 aagtcgctta aggtagtaat gcaatccaac acaatatgct acagggaaaa cagaatttcc    660
 acggtgccgc cctctggtac aagggaaaca gcacgcaaag caaaaggcca cagagggctc    720
 cctgagaatc cagtacaact aagcgaggcc ttcaactgtc aagacaaact ttgcaactgg    780
 atcccggtgg gacagtgccc tgcagcgagg agtactgtat atgccaatga gagggcccag    840
 cttccaggaa ccgttacaat ggcgtcccga gtcattttcc ctctcccact tgcattcgag    900
 agtcttcaca ctccgggaaa atcctcaagt caaggctccg atgctggggc tggcccaccg    960
 atccttggtc tgttttgccc atggacccgc ggacctcgcc tctctgcgct gcgggctcgc   1020
 aggctgtcgt cgcccatagc ggacgtcaac aaaaatatcc cgccctctaa acaccggaca   1080
 atactatcat ctagaccaga cggtagtatt ctttttcttc cgcccttctt tgtcgttact   1140
 atcacaccgc ccgcccgcgc tgacgtacaa gagaaagatg gacacacaat agaacaagat   1200
 gaaggagaga gacaacacca aatagaaaaa acagaagagg agaacacaaa caaaccaaaa   1260
 cgaaaacaga aactggctcc aggaacacca caaagcaata tgaaacctgt tcatgaaagg   1320
 agtcaggaat gccttccacc aaagaaacga gacctccccg tgaccagcga ggatatgggg   1380
 agaactacca gctgctccac taaccacaca ccctccagtg atgcttctga atggtcccga   1440
 ggggttgtgg tggctgggca gagccaggca ggagccagag tcagcctggg gggtgatgga   1500
 gctgaggcca tcaccggtct gacagtggac cagtatggca tgctgtataa ggtggctgtg   1560
 ccgcctgcca ccttttcacc aactggactc ccatctgtgg tgaatatgag tcccttgccc   1620
 ccaacgttta atgtagcgtc ttcactaatt caacatccag gcatccacta tcctccactc   1680
 cactatgctc agctcccatc cacctcgctg cagttcattg ggtctcctta tagccttccc   1740
 tatgctgtgc cacctaattt cctaccgagt cccctcctat ctccttctgc caaccttgcc   1800
 acctctcacc ttccacactt tgtgccatat gcctcacttc tggctgaagg agccactcct   1860
 cccccacagg ctccctcccc ggcccactca tttaacaaag ctccctctgc cacctcccca   1920
 tctgggcaat tgccacatca ttcaagtact cagccgctgg accttgctcc aggtcggatg   1980
 cccatttatt atcagatgtc caggctacct gctgggtata ctttgcatga aacccctcca   2040
 gcaggtgcca gcccagttct tacccctcag gagagccagt ctgctctgga agcagctgct   2100
 gcaaatggag gacagagacc acgagagcga aatttagtaa gacgggaaag tgaagccctt   2160
 gactccccca acagcaaggg tgaaggccag ggactggtgc cagtggtaga atgtgtggtg   2220
 gatggacagt tgttttcagg ttctcagact ccacgggtag aggtagcagc accagcacac   2280
 cgggggaccc cggacactga ccttgaggtc cagcgggtgg ttgccagcca agttgggcca   2340
 cagagcacaa ttctgaggac acagtgtctc tgtaaccacc tgaccttctt tgccagcgac   2400
 ttctttgtcg tgcccaggac cgtgaatgtt gaagacacga tcaaactgtt ccttcgcgtg   2460
 accaacaatc ctgttggggt gtcactgctg gccagccttt taggatttta tgtgatcaca   2520
 gttgtgtggg ctcggaaaaa ggatcaagca gatatgcaga agggctgcca gacacctgcc   2580
 ggagttcatc ctcctgctcc tcagctggag gaggcaggaa ctataccaag tggaggccta   2640
 gtgaaggtca ctgtcctggc tgataatgac cccagcgctc aatttcacta ccttattcag   2700
 gtctacaccg gatatcgaag aagcgctgct acaacagcta agttgtcagt gtacctcatt   2760
 cttcctggat gcaggacaag aactcgggac ccgctgagtg gtgtgggatc caggccagta   2820
 gcaggagctg agtacaggct accaggccaa ttcggcagaa cgagcacagt ggctgcaagc   2880
 aatactcagg cagaaggtgc tgccggccac agaggtttct ggctggcaaa gcaacaccct   2940
 aaggatgctg tgacattaga actaagatgt accccttgta ggtccatcgc aaggctgtca   3000
 gacgccgggg gcgtgcccgc cggggcccga cgagtgcggt gtgccgcggt gctcgcaaat   3060
 tgctcgttgg atatgaaacg cggggtgtgt gcctcaagaa gtgctactgt gcgcaaaagg   3120
 agtgacaagg acgttgagga gttgggtgat agagaatccg cagtaggcgt gagtgacttt   3180
 ttggacggag atgcccatta tgaaagaaat ggaaataatt cccatttgta ccagagacac   3240
 aagaagacaa aaagaggagt tgcaatagca agagacaaaa tgcccccaga ctttcaggat   3300
 catgtgattc ctggccaaga aataaaagca aaatcatttt attccccagt ggattcggat   3360
 gaaaccggtg ataaaatcag gtacaactcc aagaggagac actggagaac aggcatgctg   3420
 ggtctgtaa                                                           3429



      <210> 2442
      <211> 1500
      <212> DNA
      <213> Homo sapiens


      <400> 2442
 tggaaaactt tcaacatttc atggatagaa taagtaatgg tgggttagaa gaaggaaaac     60
 ctgttgatct agttcttagc tgtgtggaca attttgaagc tcgaatgaca ataaatacag    120
 cttgtaatga acttggacaa acatggatgg aatctggggt cagtgaaaat gcagtttcag    180
 ggcatataca gcttataatt cctggagaat ctgcttgttt tgcgtgtgct ccaccacttg    240
 tagttgctgc aaatattgat gaaaagactc tgaaacgaga aggtgtttgt gcagccagtc    300
 ttcctaccac tatgggtgtg gttgctggga tcttagtaca aaacgtgtta aagtttctgt    360
 taaattttgg tactgttagt ttttaccttg gatacaatgc aatgcaggat ttttttccta    420
 ctatgtccat gaagccaaat cctcagtgtg atgacagaaa ttgcaggaag cagcaggagg    480
 aatataagaa aaaggtagca gcactgccta aacaagaggt tatacaagaa gaggaagaga    540
 taatccatga agataatgaa tggggtattg agctggtatc tgaggtttca gaagaggaac    600
 tgaaaaattt ttcaggtcca gttccagact tacctgaagg aattacagtg gcatacacaa    660
 ttccaaaaaa gcaagaagat tctgtcactg agttaacagt ggaagattct ggtgaaagct    720
 tggaagacct catggccaaa atgaagaata tgtagataat ggactgggat atattgtatt    780
 tctcatgtta aagcctcttc ccttgaaatt aaaaaaaaat tttaactgat aaaacttagg    840
 gcaacattaa ttaatgtata ttcttacctg aattgttata ctttttgaaa atcctgtgac    900
 ttgcctgttt ctccccgctc caacgaaatc attaactctc ctaaaatgtg tttcattcta    960
 gtaagaaaac ctcaaaggat attgtaggat ataaatctta cttgaaaaca tagctgttga   1020
 aatgttttgg ccttttggag tgggggaagg acaaatctga tcctgtaatc tttttctttc   1080
 cagtaatccc ttgtgtctgt tgcatgagga catggacaat aaagtagtat atgatcctca   1140
 gatacaggga gaaggacaag gcatacagct tattgattag agctggcaag catcttctca   1200
 ttatgtttgg aattgctttc tataagaaaa ttgcccacta ctactaactt gatcaacaat   1260
 gaattcaaaa tagttaacct atgaaataac atcctctcaa atgtttgctg atgaagtaca   1320
 agttgaaatg tagttattgg aaaagtctgt aacctgtgga tcatatatat tcaaagtgag   1380
 acaaaggcaa ataaaaagca gctattttca tgaatagaca aagttgattt caggaagtat   1440
 aaattatatt ctgcaccgaa caagggaaca gaaattattg catctgtgga acatatatct   1500



      <210> 2443
      <211> 5305
      <212> DNA
      <213> Homo sapiens


      <400> 2443
 gctggcggcg cccggctccg tcctgcccgc ggccggcccc cgcgtctgct ccctccccgc     60
 ccgggcccct gtcggccgcc gccagtcccc gccccgactg tgaatgaaag gcgggcgccg    120
 ccgagggctg gctgggaacg ccgcagcgac gccggcctct cgagaggcgc gcgccccgcc    180
 gagatgtacg gtgtgtgtgg ctgctatggt gccctacgcc ccaggtacaa aaggctggtt    240
 gacaacatct tccctgagga tcccgaggat ggtctggtga agaccaacat ggagaagctg    300
 accttctatg ccctctcagc tccagaaaaa cttgatcgta ttggcgccta cctctctgag    360
 aggctcatcc gtgacgtggg tcgccatcga tatgggtacg tgtgcattgc tatggaggct    420
 ttggaccagc tgctcatggc ctgccactgc cagagcatca acctcttcgt ggagagcttc    480
 ctcaagatgg tggccaagct gctggagtca gagaaaccca acctgcagat cctcggcacc    540
 aactcgtttg tgaagtttgc caacatcgag gaggacaccc cgtcctatca ccggagctat    600
 gacttctttg tgtcccgatt cagtgaaatg tgccactcga gccatgatga cttagaaatc    660
 aagaccaaaa ttcgaatgtc aggcatcaaa ggcctgcaag gggtggtgag gaagacggtg    720
 aatgatgaac tgcaggccaa tatctgggac ccacagcaca tggataagat cgttccatca    780
 ctgcttttca atctacagca tgtagaggag gcagagagcc ggtctccctc acccctccaa    840
 gcacctgaga aggagaaaga gagccccgcg gagctggctg agaggtgtct tcgggagctg    900
 ctgggccggg ctgcctttgg caacatcaaa aacgccatca agcctgttct catccatctg    960
 gataaccatt ctctttggga acccaaggtg tttgccatcc gttgctttaa aatcatcatg   1020
 tactcaattc agccgcagca ctcacacctg gtcatccagc agctcctggg ccacctggac   1080
 gccaacagcc gcagcgctgc gacggtgcgc gcgggcatcg tggaagtctt gtcggaagcc   1140
 gcggtcatcg ctgccaccgg ctctgtgggg cccacagtac tggagatgtt caaccacgct   1200
 gctgaggcag ctgcggctca gcatcgacta cgcgctgacc gggagctacg acggggcggt   1260
 cagcctcggc accaagatca tcaaggagca cgaggagcgc atgttccagg aggccgtcat   1320
 caagaccgtg ggctcctttg ccagcacgct gcccacctac cagcgctccg aggtgatcct   1380
 cttcatcatg agcaaggtcc cgcggccatc cctgcaccag gcggtggaca caggcaggac   1440
 gggggagaat aggaaccgtc tgacccagat tatgctgcta aaatccctcc tgcaggtatc   1500
 cacaggtttc cagtgcaaca acatgatgtc agccctgcct agcaacttcc tggaccgcct   1560
 tctctccacc gccctcatgg aggatgcaga aattcgactc tttgttctag agattctcat   1620
 cagtttcatt gatcgtcatg gcaaccgcca caagttctct accatcagta ccctcagtga   1680
 catctctgtc ctgaagctga aagtggacaa gtgctctcga caggacaccg tcttcatgaa   1740
 gaagcactcc cagcagctct acagacacat ctacctgagc tgcaaggagg aaacaaacgt   1800
 gcagaaacac tacgaggcgc tctatggctt gctggccctc atcagcatcg agctggctaa   1860
 cgaggaggtg gtggtggacc tcatccgtct ggtgctggct gttcaggacg tggcccaagt   1920
 caatgaggag aacttgcctg tctacaaccg ctgtgccctc tatgctctgg gcgcagccta   1980
 cctgaacctc atcagtcagc tcacaacagt gcctgccttc tgccagcaca tccatgaggt   2040
 gatagagacc aggaagaaag aggctccata catgctcccc gaggatgtgt ttgtggagag   2100
 gcccaggctg tctcagaatc ttgatggggt ggtcattgag ctcctcttcc gccagagcaa   2160
 gatcagtgaa gtcctgggag gcagtggcta caactcggac cggctctgcc tgccctacat   2220
 tcctcagctg acagatgagg atcgtttatc caagaggagg agcattggag agaccatctc   2280
 cctgcaggtg gaggtagaat cgaggaacag tccggagaag gaggaggtga gtgtccgtgc   2340
 caccgtcctg gggcagcccc acctcctgta gattggacgc tggactccag gctcccctgc   2400
 ctgcatagtg agcttaaggc tgcatggaaa gcaagcttct cgagtaattc cacacttgta   2460
 ctgactctcc ccacgtatgc gtcatagata cttcccttcg gaaaaattgt tagggtcctc   2520
 cctgctccca tgaggatatc ataaaactca ctcttgaaag gcctggctgg ggatggtggc   2580
 tcacacctgt gatcccaaca ttttggaggc tgaggcagga ggactgcttg agcccaggag   2640
 tttgagatga tctggggcaa tataaggaga ccccatctct acaaaaaata attgaaaaat   2700
 cagccaggca tggtgacgtg cacctgtggt cccaggtact caggatgctg aggtgggaga   2760
 atcacctgag cctgggaggt caaggctgct gtaagccatg atggcagcac ggcacttcag   2820
 cctaggtgac agagtgagac ctcgtctcaa aaaaattaaa aagaaaggca tgctggtcat   2880
 cattccccac tcacaggggg accgatatgc tctgggttgg aaactagaag acttaactgg   2940
 agagataagg gtgagaacag ctttcatagt gttgcttccg tatgtatcaa taaagaatct   3000
 ttttttaaat ttacactatt tttaaagcaa ttttagttac agcaaaattg agaggaaggt   3060
 acagagatcg ccctttgccc cctcccctcc cctgacacat gcacagcctc ccctcctatc   3120
 catatccccc agcagagtgg tgcatttctt acagttcaac ctgccttaac acaacagtat   3180
 catctgaagt ctgtcgttta cactggggtt cgccctcagc gttgtacatt ctgtgggttt   3240
 ggacaaatgc gtaatgacat gcatccccca ccagagtacc atacagagtc atttcctgcc   3300
 ctaaaacccc ctgtgctcca cctcttcatc tctcccctaa ccactgacag ccaagatgtt   3360
 tttttttttt ttttttaatg ctgactgtta cagttcacaa gaagtatgga ggacacacat   3420
 ctgggtggga ccgggacaga aagatttaca tggtcctcag gcatggacag gctggcattc   3480
 cccagcctct ctgcccatta gggctgatat agacatggag gacagctttg acatcaagcc   3540
 tttccccaga tgcaatcaga ggtaggagaa gtctctaggg gtcaggatca agcctccccc   3600
 taactgtgcc ctcgaccact tcatttattg gggcagatct ctaccccagg gccctcaaag   3660
 cttatccaga accttcccac ggaaggaagc tctgacttgg gctaattgga caagtaaaat   3720
 gaggttgaac gaggcatcct ccatggccct tccagctcca aggactggga acctccaatg   3780
 cgttaggcat cggggtgagt tggctgctct ctccccatag tggcgattct cccttcccaa   3840
 gaggtaagag accctcggga attgaggagt gaagtgactc agaagcgcaa ggcgaaatgc   3900
 ttacacagct acagagccac ctcctcacta gtggcctcct gggccaccag tatcagttcc   3960
 ttcctccctt caagagtcag cttagcccag aggtagcttg gtggcaaagc aggggtgcag   4020
 gggccttcat cctgtgccct tctgccatgc cacaactctc tccactctca gccatcagtg   4080
 ccagtccaga gtcccacggt ggttcctagg gccgtactgc ccagccttgc cgcaggggtg   4140
 aataaatgct tgtttggtca aatctgaatc ctggtgcctg gcattcccag ccatgcatag   4200
 tctgggctct gccatttcat ttttccccac ctgctctggc ccgtatccac tgtcccactc   4260
 tggtggggct gctctcgatc tctcccacgc tgcgctccgc catctccagg cctttgctag   4320
 tgcagaatgc cacatctgaa ccacccttcc ctccacactg gtgcagctga gcgcctgtga   4380
 actgtctgtt ctccagcgcc cggcccctgt tcagtttcct cataaacttc tctctccctg   4440
 ctcttgccca gggagcatcc cttctctctt gcccagagag cggcattttc tttgactgtt   4500
 gccaccacac agttccctag caccctgcag gtgaatatcc aatgttgctc ggtgctgaca   4560
 gtggatgaat ggatggacgt acagaggata agtcctcaga gcgagttaaa gccgagcata   4620
 gctctctctt gcatgtaatt cctatgctag caaattgtgc agtttctata gactcaccta   4680
 cagtcctgca tgtagttggt gctcacttaa tgtttgttaa atgactttat ctcatacata   4740
 tacttctgtc ctctcctact caaacaaaaa tgccaaacaa atcaaaaaat gcacgactca   4800
 gtgaattttc ataaagtgtg tatgcccacg caaccacgcc tggatgagag agtggaacac   4860
 tgtcatcatc caggggccct gcctctgtgc cccctcccct aagggagctc ccagcctgag   4920
 ttgcgttact tctggaactt tatatcaatg aaatcattct gttctgtgtc tgctgctttt   4980
 gcttaagatt atgtttaaat gatagagcat gaggctgggc gtggtggctc atgcctgtaa   5040
 tctcagcact ttgggaggcc gaggcaggtg gatcacctga ggttaggagt tcaagaccag   5100
 cctgatcaac atggtgaaac cccgtcttta ctaaaactac aaaaaattag ccgggcatgg   5160
 tggtgggcac ctgtaatctc agctactcgg gaggctgagg caggagaatc acttgaaccc   5220
 aggaggcaaa ggttgcagtg agccaagatc acgccactgc actccagcct ggatgacaga   5280
 atgagactct gtctcaaaaa aaaaa                                         5305



      <210> 2444
      <211> 6359
      <212> DNA
      <213> Homo sapiens


      <400> 2444
 gagacagtat cactctgtca cccaggctgg agtgcagtgg tgtgatcatg gctcactgca     60
 gcctcgacct ccctggactc aagcaatcct cccacctcag cctcccaagt agctgggatt    120
 ataggtgcat gccatcatgt ctggctaatt ttttaaaatt tttttgtaga gacaaggttt    180
 caccatgttg cccaggctgg tctcaaactc ttgagcccaa gcgatcctcc cgcttcagcc    240
 ccccaaagtg ctaaaattac aagcatgcac cactgcatcc agactgtata catctattct    300
 taacattcaa actttagtga gcaaagtcca aaattaatta atactgctac cttccttcaa    360
 gaaacaaata aaaaatgggc tgagcacagt ggttcacacc tgtaatccca gcaccctggg    420
 agatccaagg caggaggatc acttgaggcc aacagacagg cctgggcaac acagtgaaag    480
 tgcctccaaa aacaaacaaa taaaacctcc aaaaacaaaa aaaaacacag ggactggaga    540
 ggcacagtcg ctcatgcctg taatcccagc actttagcag gccaaggcgg gcagatcact    600
 tgaagtcagg agtttgagac cagcctggcc aacacagtga aaccccatct ccactaaaaa    660
 tataaaaagt agctgggcct ggtggcgcac atctgtaatc ccagctactt ggaaggctga    720
 gacacaagaa ttgcctgaac ccgggaggcc gaggttgcag tgagctgaga tttcgtcact    780
 gcactccagc ctgggcaaca gagcaaggcc gtctcacaaa agagtttctt agttgtaaac    840
 tcctttagtt ttgtttgcca aaaaattata attctcattc tcaaaacatt ttcactgtat    900
 gtaggagcct agcgtggtat tttattttag tacatcaaag ctaatgttcc actgccttct    960
 ggcttctgtg gattctgtcg agaagttagt ctgccacctt tttggtgatc aatctattca   1020
 tgcccagccc aaatctattt tttctggctg cttctaagat cttttacttt gggccagatg   1080
 cagcagctca tgcctgcaat cccagcactt taggatgcca tggtgggagg atagcctgaa   1140
 gccaggagct caagaccagc ctgggcagca tagtgagacc ctctatttta attttttttt   1200
 aattttaata aaaaataaga tcttttactt tggtgctcta caatcatatt atgccacata   1260
 taggtatgga tttttttgta tttttcctat ttggaatatt tggtgttgat cagaaaattc   1320
 gaaaagtttt ctagaaattg ttttttttcc cattctttct ctgccctgtg caactctgat   1380
 gagttgcaca ctaagccttc tttttttgag gcagagtctc gctctctcac cccggctgga   1440
 atgcagtggc acgatctccg ctcactgtaa cctctgcctc ctgggttcaa ccaattctcc   1500
 tgcctcagcc tcccaagcag ctgtgaccac aggcacccac caccacacct ggctaaattt   1560
 tgtattttta gtagagagag atggggtttc gccatgttgg ccagactggt ctcgaactcc   1620
 tgacctcagg tgatctgccc acctcagcct cccaaagtgc tgggattaca ggcgtgagcc   1680
 accacacctg gcctaaaact ctttttgttt tgagacagag tcttactcta tcgcccgggc   1740
 tggagtgcag tggcacgatc tcagcccact gcagccccca cctcccatgc tccagcaatt   1800
 cttgtgcccc agcttcccga gtagctgaaa gtacagaggc acaccaccat gcccggacaa   1860
 tcttcatatt tccagtagag aaggggcctc accatgttgg ccaggctgct cctgaactcc   1920
 tgaactcaaa agacccgccc acccctgccg agaccagctc ggtcactaac tcagcagcgc   1980
 tagaggaatt aaagacacac acacaaaaat atagaggtgt gaagtagaaa atcaggggtc   2040
 tcacagcctt cagagctgag agcccccaac agagatttac ccacatattt attaactgtg   2100
 gggaaaagag agatcagatt gttactgtgt ctgtgtagaa agaagtagac ataggagact   2160
 ccattttgtt ctgtattaag aaaaattctt ctgccttgag atgccgttaa tctgtaacct   2220
 tacccccaac cctgtgctcc ctgaaacatg tgctgtgtca actcagggtt aaatggatta   2280
 agggctgtgc aagatgtgct ttgttaaaca aatgcttgaa ggcagcatgc tccttaagag   2340
 tcatcaccac tccctaatct caaaccactc cctaatctca agtacccaga gacgcaaaat   2400
 actgcaaagg ccgcagggac ctctgcctag gaaagccagg tattgtccaa ggtttctccc   2460
 catgtgatag tctgaaatat ggcctcgtgg gaagggaaag acctgaccat cccccagccc   2520
 gacacccata aagggtctgt gctgaggagg attagtaaaa gaggaaggaa cacctctttg   2580
 cagttgagat aagaggaagg cttctgtctc ctgctcgtct ctgggcaatg gaatgtctgg   2640
 gtgtaaagcc gatttacttt acatggaata tacttccatc tactgagata ggggaaaacc   2700
 gccttagggc tgtaggtatg acatgcgggc agcaatactg ctcttcaagg cattgagatg   2760
 tttatgtgta tacatatcta aagcacagca cttaattctt taccttgttt atgatgcaga   2820
 gacctttgtt catgtgttta ccttctgacc ttctctccac tattatccta ttatcctgcc   2880
 atgctcgata atgatcaata aatactaagg gaactcagag gccggtgcca gtgtggatcc   2940
 tctgtatgct gaatgctggt cccctgggcc cacttttctt tctctatact ttgtctctgt   3000
 gtctcttttc caagtctctc gttccaccta acgagaaaca cccacaggtg tggaggggca   3060
 acccacccct tcatttaaca gcaaaccagt cattagcatt gtttctatag atattaaatt   3120
 aactaaaagt atcccttatg ggaaacaaag ggatgggctg aattaattgc agcaggaaca   3180
 cacccgtaag acacagatcg ctcatgcttt tgtttgtggc ttaagaatgc ctttaagcgg   3240
 ttttccgccc tgggcaggcc aggtgttcct tgctctcatt cccataaacc cacaaccttc   3300
 cagattgggc gttagggcca ttatggacat gttttagtgc tgcagaggtt ttgcttatgg   3360
 ccagttttgg ggccagttta tggccagact ctggggggct tgctcccaac atgtctccct   3420
 tcttcgattt gcaaagagac tctcgcagga gtcgggatcc gcatctgcag actatacaaa   3480
 ggcaaacaac agattaaaaa gcatagtcat cattgaaatc acagagcttc caagtgtttt   3540
 tacccattta aatgggttac tagctgctaa tttttctgca gctcctttaa gcactctggt   3600
 tcctggcatt aaggtcaggt tgcccgggat gctttacata tttgttcttt taattttgct   3660
 atatccaaaa acaagtttgt agagtgtcct tctagatact cttttattct ttcccaaatt   3720
 ttgatcttat taagagcatt taatagtttt tacaaatcct tatgtttagc tcctagagcg   3780
 ggccatatta tttgaggttg aggtgccact ataccgccat ggttccagat aataggaact   3840
 tttgccgtac ttaacatttc taccatctga ctgttttgtt cagatcatct gaacatagtg   3900
 tgaccgtggc atgcagactg agaggtgcaa ttcaagctaa acatcccctt gggggaccaa   3960
 ttagtaatga ttccatagga atcgttgtgc agcatctctg cctattctgc aaagcaatct   4020
 tcctaaataa gtacgttcat tttttctaac tgggtccaat cctgtttaca aataggtttt   4080
 tgagggtggt atgcctcaat tataggagcc gatttattat ggtaaatact gagatcagaa   4140
 agcatgtgta actgtgtcat agaatgattg catccaggca ttattaccag cccttattga   4200
 aggaatactc acggcagtgg tgataactgc tatcatagct accattaaat tattcattgt   4260
 gactggttgt cccgctttcc tcaggttttc ttccgccatc tgtgacagct tcttgatctg   4320
 ttcttagcgg ggtggctgtg ttcgacgggt gttgctcatg atagttggag tcctcctcag   4380
 cgtcagtctc tacgtggctg caaccagggg gtcctctgga tcctcccaga gtctcttcct   4440
 tggcatctgg ctcatgataa ggtttcaggt gtcttgaagg tatccaaatc ggctgttgat   4500
 tttggccacg gggattgctt taagagtact caggtgtcct ccagctagtt ttccattcca   4560
 accgtcgctc ctgcgaccct ttgacctgga ttcgagcccc caggaataga agccacttgc   4620
 cgagaccagc tcagtcaggg agaccctaac ccagcagcac ttggtcagct ggtccccctc   4680
 gcgccagagg cagaagcctg agcagagggt ctctccgcgt ctgtactctg gcgtctctcg   4740
 gtgtgtgggc agcgtgaccg acctcagcgc gatgacatag gggtccccat tgtcacaagg   4800
 cttccgcctc gaggccagga tcacgaagtc ctggggcttt gtgtgacctc cgagggcagg   4860
 gctggtgacg tggtagatgg cgtcgtcctc gtctacctgc tgcactagct ccacgctccg   4920
 gtagtgcttg tcccactctg gcctctgacg caggtccgag agcagcagga aggcctgggc   4980
 tgcatccaca tgcaccacca tctccatgtg gaaggagagg aacttgtcat cctccagagt   5040
 gtacaggcgg acctgactga tctccgagga cagcacccag ttgtccttgg ccacaagcat   5100
 cttcaaggag gagacgttat tgtagctcag gtacacctgg ttgctagggt cccaggggac   5160
 ggagaggggc acctctgtct gcttacagga cacgatgtac ttcctgtcca ggcggatctt   5220
 ctttctggca ctggcctctc ggtaccgccg ctcaccatcg ccgggctggg gccgaatcca   5280
 gggcagcaac tggggctggt catctgcgtc caggaccaca aaggtcataa aggcactgtt   5340
 gatgtggcgc cggtgggtct cagcctcctg gcgataggcc tccacgcaca cgcccacctc   5400
 catgctatgt ttgaaggcat tgttcacgat ggctttgagc accagacggt cgccgacctg   5460
 ggacgggcct cggaagtgga acatttcaat ggccttcagc gtagggtggg cacggcagag   5520
 ccggctggct gcaatggtgg ccacattctc catccaggcc atgatctggc ccccaaaggt   5580
 gttgccctgg tgattggcgt ggggaggcag gaccagctcc acactctcca cacgggtctt   5640
 ctcagccggc accatgcggc tacagtctct gctctccaga tcgccctgaa tggcgcagtt   5700
 ggccaggagg tccttgatgg tgtctgcata gacaaggcgc atgcgccggc gctcagccgc   5760
 cacactgtgc tccatcttct cctcttctgt ccgcggcgtg atctgcttca gcttcacctt   5820
 ggtgatctct cggcgggcca cgaaggtggc caaggccttg cacacattcc actgcttctc   5880
 agagcacagg tcctccgagg ccacctggat gcccacctcc atgctggagt tgaaggcccg   5940
 gttcaccttg gccttgatat tcaccacttg tccaacacta atggtgtgct caaaatagat   6000
 gtcatccatg gaagctgtga cacaggggca gccagcgtgc ctctccgcgg acaggcaagc   6060
 cgtggtgtca atccacttga gcagctgccc gacgctcagc tcaccacgtt ggttggtgtg   6120
 gcagggcagc accagctggc tcatctgcac ctccgtgggg ttccggtatc cctcgccgtc   6180
 tgccatggca ctgtcgttcc ccgcacgtaa ggctgacttc cgggatgtgc ggttggagaa   6240
 cacagaggcc aagccccgtc gcaggtgatt tccgacattc tggatcatcg cgccgggtgg   6300
 ccggggaaag cagcgccctc ccagagacac aagctggtca cctgagcaac agccaggcc    6359



      <210> 2445
      <211> 954
      <212> DNA
      <213> Homo sapiens


      <400> 2445
 ttttaagctt ttggatgatt tttattgatt tcatgccatt attaaggtta ataccctcag     60
 aatctccata ggcagtagta gcccaaccca ggccctgcag ggcccagctc ttggcgactt    120
 tcacattcca agaaacttgg tttagaaatc aaaggtaatt taaaagttat ttgaatcttt    180
 actgtcattg cttgaagaat attaaaaaga attcaacttg taacctataa tgggaggctt    240
 aaatcctcct tggccccatt cttcttcttt tttcccccct tttctttttt cccttcattc    300
 ctcttgcttc agtatgtcca tgggctgact taaagccccc ctctcaaaat ctctgccaaa    360
 attctctccg aacttgattc cttgtgattc ttggttttgc ttttcatccc ccttcctttg    420
 gcttctattc cttctttctt cccaccagga aatcacagcc cttggcatca tcttggcact    480
 cacacttgtt tcttcactca gcccttttct ccttggtcac tgattctgct ccatgagcag    540
 tcagaaatgg agctggcaag ctcagcctct cagctggaga cactggagtc agggccctgt    600
 cccctccctg cccgcaaaac tactcttcaa aggcttcctt ccgggcaccg cgaagccagc    660
 gtgctcagca ttcagggagg cagcggcgct cgccttcatc caggacaaca aaactgccat    720
 ttccgaagag aaaggaaacg gctcgcggtt tctggggttc ccaagcgcgc gcctgcgagg    780
 gaggccgcga gccgagtcgc cacgcccaga accccgagcc cgcccccgcg ccacccagcc    840
 cggccccgcc gccccggctg cgcacgcgac gccccctcca ggccccgctc ctgcgcccta    900
 tttggtcatt cggggggcaa gcggcgggag gggaaacgtg cgcggcccga aggg          954



      <210> 2446
      <211> 622
      <212> DNA
      <213> Homo sapiens


      <400> 2446
 ccttttttgg aacgccccgg tccggaattc ccgggtcgac ccacgcgtcc gctggaaccc     60
 tctgggcagc ctagctgaat gcaggatccc cctcgcccca gagaactcct tttccaggag    120
 accaaggtgg gtcccagaat ctgcaagttc agtaatagcc ccaggtgatt ctcatgcagg    180
 caggtgagac ctgcactttg agatccaggt gctactcgaa gccctgcggg ggctttgttc    240
 actgtaccca aagcatcgtg aaggttcctt gaaggtacat ccagggcatc tgtgctggat    300
 gcccaccgtg acccggcctg gcactccacc ttcacaggcc agcacaggag cccaagagct    360
 cccgggagga gaaaaaaaga cctgccgctg ggagaagaaa aaaaagacct ttcccgggtc    420
 tgcaggactc acaggtaaat ccattgagag acttacccgg ccagccttgt acttgagacc    480
 gctgctgttc tcctcctttc ctgtccgcgt gacgctggag gccctgccag ggggcgttcc    540
 aaaacgctca gcctcccgga tgcctgtgga gatgaagaga ggaccatttt gagtcagcag    600
 gggaggctca gtcagcacga aa                                             622



      <210> 2447
      <211> 1325
      <212> DNA
      <213> Homo sapiens


      <400> 2447
 ttaaacataa tacttggaag aaagggctcc atgtgcctag aagagaggta ctgagaggaa     60
 gactcacttt ggaggctgta gcatacaatt ttcagatatt gcctcaggta aaaatatact    120
 tcctggactt tgttttctga cacataagag gtgtgttctg ctccctgtaa agacaagggt    180
 gggtatccag atggtcccat gagtagggct gcacaagatg ctggaggctt ggtaagttcc    240
 tctgggtcgc agatcggttt ctcgggtcgg gatagtgtga gtgcctagca cacgtgtcgg    300
 gcacgcagaa gggcccctta aaagtttctc tttcatcctg gccagtttta gatacacaat    360
 tttgtcagtt tacttacagt gcatactctt gggtaatact tgtgctgacc aagtatctta    420
 gaggcttatt ttattatagt agccaacatt tatccagcac ttaccttata taaagggctg    480
 tttgtgcatg agctcattaa aatcgtgaca gcagaccaat gagtgagaaa ctgccccatt    540
 ttgaaggtga ggaaattgag gttctgggta taactttctt tggtcacata atattaaatt    600
 ttacaatttg agccttgagc catacacaaa accaccacaa aattagattt atagactcaa    660
 aatgaaaaca tcagcttact ggtttgtagt tcataccagt catacattcc aaaacatgtt    720
 ttgagtctta ctctgtgcct gaccttgtgc ttgataacag ggatataatg ggaagcaaca    780
 ctccagtggt cagatgctca cagtcttatg gaggagccca aataatatct ggggaagtta    840
 aagtccatat aatgactgat aagagtacaa tacaggtgcc catgggaaca cgtgacatcc    900
 actgaagact gcctggaagg ggaaacagcg tgtgttcatg ccctatacgg ataaacatga    960
 taccataatg aaaatgctta tcctttagga gaaaaggaga gccttagagt agccaggatc   1020
 aaggatgaaa gctggacttc aaatatgcct tgttagtgta aatgtgactg tggaactgta   1080
 tgagtatttt aagattatgg agtaaagtaa gttttaaaaa gcagtcccta atcatcaaaa   1140
 gtaaaaaact cttgatgtag tcatataacc acactaagaa ctcttccagg tgacttcaaa   1200
 acgataggac agtacatctc tagtagaata tgccctgaga atgaaaagaa tgtaacagtg   1260
 ttagtatttt gaataaacat gttattacca aaaaaaaaaa aaaaaaaaaa aaaaaaagtc   1320
 gtatc                                                               1325



      <210> 2448
      <211> 1462
      <212> DNA
      <213> Homo sapiens


      <400> 2448
 atgaaagcca tgccctggaa ctggacctgc cttctctccc acctcctcat ggtgggcatg     60
 ggctcctcca ctttgctcac ccggcagcca gccccgctgt cccagaagca gcggtcattt    120
 gtcacattcc gaggagagcc cgccgagggt ttcaatcacc tggtggtgga tgagaggaca    180
 ggacacattt acttgggggc cgtcaatcgg atttacaagc tctccagcga cctgaaggtc    240
 ttggtgacgc atgagacagg gccggacgag gacaacccca agtgttaccc accccgcatc    300
 gtccagacct gcaatgagcc cctgaccacc accaacaatg tcaacaagat gctcctcata    360
 gactacaagg agaacaggct gattgcctgt gggagcctgt accaaggcat ctgcaagctg    420
 ctgaggctgg aggacctctt caagctgggg gagccttatc ataagaagga gcactatctg    480
 tcaggtgtca acgagagcgg ctcggtcttt ggagtgatcg tctcctacag caacctggat    540
 gacaagctgt tcattgccac ggcagtggat gggaagcccg agtattttcc caccatctcc    600
 agccggaaac tgaccaagaa ctctgaggcg gatggcatgt tcgcgtacgt cttccatgat    660
 gagttcgtgg cctcgatgat taagatccct tcggacacct tcaccatcat ccctgacttt    720
 gatatctact atgtctatgg ttttagcagt ggcaactttg tctacttttt gaccctccaa    780
 cctgagatgg tgtctccacc aggctccacc accaaggagc aggtgtatac atccaagctc    840
 gtgaggcttt gcaaggagga cacagccttc aactcctatg tagaggtgcc cattggctgt    900
 gagcgcagtg gggtggagta ccgcctgctg caggctgcct acctgtccaa agcgggggcc    960
 gtgcttggca ggacccttgg agtccatcca gatgatgacc tgctcttcac cgtcttctcc   1020
 aagggccaga agcggaaaat gaaatccctg gatgagtcgg ccctgtgcat cttcatcttg   1080
 aagcagataa atgaccgcat taaggagcgg ctgcagtctt gttaccgggg cgagggcacg   1140
 ctggacctgg cctggctcaa ggtgaaggac atcccctgca gcagtgcgat ccgggtggat   1200
 ggacccaggg gcaacgccct ccagtatgag acggtgcagg tggtggaccc cggcccagtc   1260
 ctccgggata tggccttctc caaggaccac gagcaactct acatcatgtc agagaggcag   1320
 tcacaggagc tctgccctcc ccaagagctc gatgacatct tctcctgttg tcagactccc   1380
 cgttctcccg acttcagcca tactgggacc cactgtgccc tggatgaggc tgccatggct   1440
 tgggaatggt ctcattccca ag                                            1462



      <210> 2449
      <211> 348
      <212> DNA
      <213> Homo sapiens


      <400> 2449
 gggatgtctg tgaggactct ttccaaataa gatcccattc tcagttctgg agattaggac     60
 ctgggcacat ctttctggga gacaccactc agcccactgc actagctgtg cgtggcccca    120
 ggttgcctgc ttaccattgg cgacacatcc cagctgcacc tgcacgttct gcagcctcca    180
 ggcccctgga cggcctgggc aaagccctct gagccccaga cgggcctgtg ggcctgaaga    240
 cctgccccct cctccttatg tctgagacct agccccttcc ttggggccgt ccctgggtcc    300
 actgatgtcc caatcccagc cacgtagaac tccaccactg agaggccg                 348



      <210> 2450
      <211> 1587
      <212> DNA
      <213> Homo sapiens


      <400> 2450
 tcacttggac tcggaatcag gaaaccaggg gttgtaaccc agactctgcc accaaccaac     60
 aacgttgctt agagaaatta cttctgcctt caggatctca gtgtcctcgt ctacaatcat    120
 ccatgcacca cgtgggacaa cagaggaatt ttcaatgccc aatgtagtta gtgatagagc    180
 taacggctga gagtggccgg agggtggtgg ccggtacagc agtgtaccca gtgcagtcca    240
 ccacgcccgc acttgtctgg cagcagagtt gagcggcact tccaggcccc aggaaccacg    300
 ggcacttcct cctgaaactg gggtggctac agctgaagct gagaagagca accagcctgc    360
 tgctatttcc aaaaccaaat gggcaggggg ctccgctgca gagggctcgc cgaggctctc    420
 gccttcaccc ggcgccgcgc aggtgcccgc tctccccatg caggacatgt cagaagggtc    480
 ctcttcccct tctccaccgg gggggcacat ttggttggcg agtttgacgc cctgcagcct    540
 ggctctgtgg aacagttgct gccaaagccc ggggagccag ccacgggggc gagatgaagg    600
 agattgtctg gtgagagcca cagagccatc tgccaccggc cccgaccccc gcaggacgcg    660
 cctgtgctcc atttctgcat ctctcgtggt ccgtaatact ccagatccag gaatttctga    720
 caggagacca gggatttctg acaggagacc aggaacttct gacaggagac cagggacttc    780
 tgacaggaga ccagggattt ctgacaggag accaggaact tctgacagga gaccagggac    840
 ttctgacagg agaccaggga cttctgacag gagaccagga acttctgaca ggagaccagg    900
 gatttctgac aggagaccag gaacttctga caggagacca gggatttctg acaggagacc    960
 agggacttct gacaggagac cagggatttc tgacaggaga ccagggactt ctgacaggag   1020
 accagggact tctgacagga gaccagggat ttcacgtcta ccacgtgact ggattcctgc   1080
 ggccgccgcg agccgggaga attctaatag cgcagatgcc cggaaccgct gcagcagccc   1140
 gagccggaag tgccagactc ctacttccca ccggatgcgg ggctcggcag gctcggtagg   1200
 ctcctccgca ggccacacag ccggcggcac aggcctccca actccttcca ggtgttccca   1260
 ggccttgcag gtgttcccag cggtactggg gaagaggggc ttcttatcat gggagagatc   1320
 tctgaagcag agggacatca ggggccctga tttctcaagc acggcgctca tataaccctc   1380
 aagccctttg agggcagctc cagaatccag ctctgcctgc ttggtctttg aattcctaga   1440
 gcctgctctc aggaatggcc ttgacagagc cgacttcccg ctggaaggat actgggggct   1500
 cctccagcac attctctcac agggggcagc acttagagcc caaaacggga agggaaggag   1560
 ggtctggctc gagtggcagg accccat                                       1587



      <210> 2451
      <211> 2550
      <212> DNA
      <213> Homo sapiens


      <400> 2451
 atgagaaagt acaacagcct tgttgttgat atgaggaagg tttcagtggt ttggatagac     60
 caagctagcc acaacattcc cttaagccaa agccaaatcc agatcaggcc cttcaattct    120
 gtgaaggctg agagaggtga ggaagctaca gaagaagagt tggaagctaa cacagctagc    180
 ggctgtgcct ctcgacttca cagctatctt ctggctctcc actgcttcac tgtgcgcctt    240
 tgtggtgtgc cctctcccca cctgtttgcc tccagcactg cttctttgcc agagtcacct    300
 ggttgctgca tgcactcact ggtcactaaa tccccatgcg gggatcctct agagcccgac    360
 gatgccacct tgtttaaaca aaatctcttc tacttggaga ctctcaacac caagcagaag    420
 ctgtaccaca agaagatctt ccggactgcc atgctgttcc agtttgtgaa cgtgctgctc    480
 caggtcctgg tccacaagtc ccatgatctt ctgcaggagg agattggcat cgccatctac    540
 aacatggcct cagtcgactt tgatggcttc tttgccgcct tcctcccaga gttcctgacc    600
 agctgtgatg gtgtggatgc caaccagaaa agtgtgctgg ggcggaattt caagatggat    660
 cgggtgtgcg agggaatcag ttctctaagt cgactgcaga atgagctcag ctatatcgag    720
 aagtttactg actttcttcg gctctttgtg agtgttcacc taagaagaat cgagtcttac    780
 tcccagttcc ctgtggtgga gtttttgaca cttttgttca agtacacatt tcatcaggat    840
 ttagacatac aaccttcaca agcagtcttt ggcggcattg agtttactta cattctagtg    900
 accctagtca ttctaggcac gcagcgggtc cccaagccgg gctgcggcca gggcgggcgc    960
 gccaactgcc ccaactcggg cgccaacgcc acggccaacg gcaccgccgc ccccgccgcc   1020
 gccgccgccg ccgccaccgc ctacggggaa cggcccacct ggcggcgcgc tgatacagct   1080
 gggagaccgg cgacgaacgc ttccgcttca ggatttccac accgtatcga attaaaagcg   1140
 ggcaaaacaa tcacgctgga agatggaagg cagattaacg gcgcagatta cttagctgct   1200
 ccagtgccag gtaaagcgct cgctattttc ggcgataccg gcccctgcga tgccgcactt   1260
 gacctggcta aaggtgtcga tgtcatggtg cacgaagcga cgctggatat aaccatggaa   1320
 gccaaagcca atagtcgcgg ccatagctct acacgccagg ctgcgacact agcccgtgag   1380
 gctggagtcg gcaagctaat cattacccac gtcagctcgc gctatgatga caaaggttgt   1440
 cagcacctgt tacgtgaatg cagagatttc aaggctacgc ggccaaacga gaagtgggtt   1500
 accgatgtta ctgaatttgc agtcaatggg cgcaagctgt atttgtctcc agtaatagat   1560
 ctcttcaaca acgaagttat ttcttacagc ctttcggaaa gaccagtgat gaacatggtt   1620
 gagaatatgc tcgatcaggc attcaaaaag cttaatcctc acgagcatcc tgttctgcac   1680
 tctgaccagg gatggcagta tcgtatgaga agatatcaaa atatccttaa agaacatggt   1740
 attaaacaaa gcatgtccag aaaaggcaat tgtctggata atgctgtggt ggagtgtttc   1800
 tttggaacct taaagtcgga gtgtttttat cttgatgagt tcagtaatat aagcgaactg   1860
 aaggatgctg ttacggaata tattgaatac tacaacagca gaagaattag cctgaaatta   1920
 aaagcattag ccgtggcgct ggcgaacatc gacccgatca tcgaactgac gtcatgcgcc   1980
 gacgcctgca agcgaactgc gctggttgct aatccgtggc agctgggcaa cgtccgcgat   2040
 gctcgaactt acaaagagct gctggatcag atcgcggaac tgttgcgtat tcttggtagc   2100
 gccgatcgtc tgatggaagt gatccgtgaa gagctggagc tggttcgtga acagttcggt   2160
 gacaaacgtc gtactgaaat caccgccaac agcgcagaca tcaacctgga agatctgatc   2220
 acccaggaag atgtggtcgt gacgctctct caccagggct acgttaagta tcagccgctt   2280
 tctgaatacg aagcgcagcg tcgtggcggg aaaggtaaat ctgccgcacg tattaaagaa   2340
 gaagacttta tcgaccgact gctggtggcg aacactcacg accatattct gtgcttctcc   2400
 agccgtggtc gcgtctattc gatgaaagtt tatcagttgc cggaagccac tcgtggcgcg   2460
 cgcggtcgtc cgatcgtcaa cctgctgccg ctggagcagg acgaacgtat cactgcgatc   2520
 ctgccagtga ccgagttggg gatcctctag                                    2550



      <210> 2452
      <211> 1404
      <212> DNA
      <213> Homo sapiens


      <400> 2452
 cggcgggcgg tggctttggg gccgaagtgg gcgtgcggct cgcgctgttc gcggccttcc     60
 tggtgacgga gctgctcccc ccgttccaga gactcatcca gccggaggag atgtggctct    120
 accggaaccc ctacgtggag gcggagtatt tccccaccaa gccgatgttt gttattgcat    180
 ttctctctcc actgtctctg atcttcctgg ccaaatttct caagaaggca gacacaagag    240
 acagcagaca agcctgcctg gctgccagcc ttgccctggc tctgaatggc gtctttacca    300
 acacaataaa actgatcgta gggaggccac gcccagattt cttctaccgc tgcttccctg    360
 atgggctagc ccattctgac ttgatgtgta caggggataa ggacgtggtg aatgagggcc    420
 gaaagagctt ccccagtgga cattcttcct ttgcatttgc tggtctggcc tttgcgtcct    480
 tctacctggc agggaagtta cactgcttca caccacaagg ccgtgggaaa tcttggaggt    540
 tctgtgcctt tctgtcacct ctactttttg cagctgtgat tgcactgtcc cgcacatgtg    600
 actacaagca tcactggcaa ggacccttta aatggtgaaa atgggcagat gaatagcaat    660
 aagtggacct ttgttactct tctgagttag aaaaattcta atttagtaca ctctgaacaa    720
 agcttattat acttacttaa gatgtgtttt gatttggtgt tcagaaagca acctgacaat    780
 gataatactg taactatgat aaaattgaga ataaaaagat tttatttaga aatcataagt    840
 ctggaattga ggttatttta gccccacagt agagtatcct ggagggccag gtcctctatg    900
 ctatgtgtat gtaataggat ttaggagcct aatattaaga gaagaccttg tttccactct    960
 cttcagatgt actagttgga tccatgattg gaatgacatt tgcctatgtc tgctatcggc   1020
 agtattatcc tcctctgact gatgcagaat gccataaacc atttcaagac aaacttgtac   1080
 tttccactgc acagaagcct ggggattctt attgttttga tatttaaaaa ttgaatctgg   1140
 ccgggcgtgg tggctcatgc ctgtaatccc aacactttgg gaggctgagg agggtggatc   1200
 acctgaggtc aggaccagcc tggccaacat ggggaaccct gtctctacta aaaatacaaa   1260
 aattagccag gagttgtgtg ccgtaatccc agctacctgg gaggctgagg taggagaatt   1320
 gcttgaacct gggagctgga ggttccagtg agccgagatc gcaccactgc actccagcct   1380
 aggcaacaga gtgagacccc gtct                                          1404



      <210> 2453
      <211> 2304
      <212> DNA
      <213> Homo sapiens


      <400> 2453
 atgggctggg actgcggctt ggctcgctgg gcaagggtag ggctgcggga gcgagcggcg     60
 gtccagcccc tggcgcccgg gtgcgcggcc atgtcttttg cctttcctcc ttttattcct    120
 caaggctaca agactgcttt tggtgttggc accaacaaaa ttgttacgca agacaatagg    180
 tgggaactac caggggcctg gtatttcccc agagcctcct cccaggccag ggagatgcca    240
 cagtgcccga ctttggaaag ccaggaaggg gaaaactccg aagagaaggg ggacagttcc    300
 aaagaagatc caaaagaaac cgtcgcgctg gcttttgtga gagagaaccc aggggcacaa    360
 aacggacttc agaatgccca gcagcaaggc aagaagaaga ggaagaaaaa gaggttagga    420
 ttgaaagctg gggaatgggg agccatgttg atgattggtg atcaatctat ccagctgccg    480
 gcctttcttt cttcaatagt gcgcagggct gcccaacagt acggctttag agagggaggg    540
 gaagacgatg actggactct ctattggaca gattactcag tgtcactgga gcgggtgatg    600
 gaaatgaaaa gttaccagaa gatcaatcac ttccccggga tgagtgaaat ctgccggaag    660
 gacttgctgg ccaggaacat gagccgcatg ttaaagatgt tccctaaaga tttccgcttt    720
 ttccctagga cctggtgtct tcctgctgac tggggagatt tgcagaccta cagcaggtca    780
 agaaaaaata agacatacat ttgtaagccg gattcgggct gccaagggaa aggtatattc    840
 atcacccgga cagtgaaaga aatcaaacca ggggaggata tgatctgtca gctgtatatt    900
 tcaaagccct ttatcattga tgggtttaag tttgacctac ggatttatgt actggtgaca    960
 tcctgtgacc ctctcaggat ttttgtgtac aatgaaggac tggcccgctt tgcgacgacc   1020
 tcttactccc gcccttgcac agacaacctg gatgatatct gcatgcacct gactaattat   1080
 tccattaata agcacagttc aaatttcagt cgagatgcac actctggcag taagaggaag   1140
 ctctccacct tcagtgcata cttggaggac cacagctaca acgtggagca gatatggagg   1200
 gatattgagg acgtcatcat caagaccctc atctcggccc accccatcat caggcataac   1260
 taccacacct gcttccccaa ccacacactc aacagcgcct gctttgagat cctgggcttt   1320
 gacattttgt tggaccacaa actcaaaccc tggctgctgg aggtcaacca ctctccaagc   1380
 ttctccaccg actctcggtt ggataaagag gtgaaagatg gtctgctgta tgacacctta   1440
 gtcctgatca acctggaaag ctgtgacaag aagaaagtct tggaggagga gagacaacgg   1500
 gggcagttcc tgcagcagtg ttgttctcgg gagatgagga ttgaggaagc caagggtttc   1560
 cgggccgtgc agttaaagaa aactgaaacg tatgagaagg aaaactgtgg agggttccga   1620
 ctgatttatc ccagtctgaa ttcggagaag tatgagaagt ttttccagga caacaactcc   1680
 ctcttccaga atactgttgc ttccagggct cgggaggagt atgcccggca actgatccag   1740
 gagctgagac taaaacggga gaaaaagccc ttccaaatga agaagaaggt agagatgcag   1800
 ggggaatcgg caggcgagca agtgagaaag aagggcatga ggggctggca acagaaacaa   1860
 cagcagaaag acaaggccgc cacccaagcc tccaaacagt acatccagcc attgacatta   1920
 gtatcctaca cacctgactt gctcttgagt gtcagaggtg aaaggaaaaa tgaaacagac   1980
 agcagcctca accaggaggc tcccacggag gaggccagct ctgttttccc caagctgacg   2040
 tctgcgaagc ccttcagttc tctacccgat ctgaggaata tcaatctcag cagctcgaag   2100
 ttggagccca gtaaacccaa cttcagcatc aaggaggcca agtctgcctc tgcagtgaac   2160
 gtattcactg gcactgtggt aagtattctg gaggctgaga agtccaagat caaggtgctg   2220
 gcaagtttga tgtctggtga gggcctattc ctcatagacg gcagcttctt gctgtgtcct   2280
 cacacagtgg aaggagctag ttaa                                          2304



      <210> 2454
      <211> 1518
      <212> DNA
      <213> Homo sapiens


      <400> 2454
 atggttaata ctgagcgtca acttgattgg attgaaagat gccaagtatt gatcttagct     60
 ttatctgagg agataaaccc tgagctgcct gaggcaattg tgatggcctc ctctgaggta    120
 gttaccaggc aagataatat tgattctcct caggagccac ccccaacacc cctgtttgct    180
 tctagacctg taactagact aaagtcctgg cgagccccta gagtgcgtcc agtgggtccc    240
 cggactcatc ctgtggtcat ttccccagtg ccagaatgca taattagcat agacatactt    300
 cgaagctggc agaaccccca cattggcacc ctgactggta gggtgagggc tgttatggtg    360
 agaaaggcca aatggaagcc attagagctg tctctaccta gaaaaatagt aaaccaaaaa    420
 caatattgtg tccctggagg gattgtggag attagtgcca ccaccaagga cttgaaagat    480
 gcaaaggtgg tgattcccac catatccctg ttcaactatc ctatttggct tgtgcagaag    540
 aatgatggat cttggagaat ggcagtggat tatcataagc ttacccaagg ggtgactcca    600
 attgcagctg ctgtaccaaa tgtgatttca ttgcttgagc aaattaacac atcttctggt    660
 acctggtatg cagccattta cttggtaaat gtctttttct ccattcctgt ccataaggcc    720
 ctcaagaaac aatttgcctt cagctggcaa ggtcaaccat atacctttac cattctacct    780
 tgggggcata tcaactctcc gactttgtgt tataatctca tttggagaga acttgatcac    840
 ttttcgcttc cacaagatat cacactggtt cattacattg atgacattat gctaattgga    900
 tccagtgagc aagaagtagc aaacacactg gacttattgg agaaggctct gcaacaggtc    960
 caggctgctg tgcaagctgc tctaccactt gggccatatg acccagcaga tccagtggtg   1020
 cttgaggtgt cagtggcaga tagggatact gtttggagcc tatgctcctg ctgctacact   1080
 ccctggtttg ggacactttc tcatgtcagc aatttgcaaa cctggagccc atgtccccct   1140
 ccagtgtccc cagtggggtc ccagagacct cagctgtcac gtgagaaaaa caaaaatact   1200
 aaacgtattc attccatccc cgaagtatta attatgaaac catatttcac agctgttgct   1260
 aaaccatctc tgctttccca taagtggctc cctttagaaa aaccagaaaa tccttgctgt   1320
 tattcctcag atcacagaac agcagtcccc aacctgctcc tttatcgacg gagcaccagg   1380
 agaaaaacag agctcactaa caaggaactc acttcggcac acttcactgg agacttaccc   1440
 aggcgagctg tgtgggtttt aggagacaga acagcagtcc gtccttcact ggagcaaggc   1500
 atggcattgt ggatttga                                                 1518



      <210> 2455
      <211> 1231
      <212> DNA
      <213> Homo sapiens


      <400> 2455
 aaaaggaagc acagaagcct ttatttctgg tacggctggg tgggggactg gtctcctccc     60
 gtcctctgcc gggctgcctg ggggttgggg gcctgctggt gggtgggccg gcactgacag    120
 gagagggccg cgtgccaggc ccatcccaca gaaaagccct ccttggccat ggtcgggaga    180
 tgcagccaaa ggacagtcag gcttcctccc ggtggcggcg tgggctgggc agggaaggct    240
 tcccggagga ggcatcattg tccactgaga agcaccgtgg ggcctggcca ctgcctgtgt    300
 gtctgcttgg agctgggcac ggctgggccc ttcaaactct gctgcagccg tgggaggaca    360
 gcagggtgag gggtgtggca gggtgggggg catggtgggg cagggaaggt gctgggggga    420
 ccacaggcgg gacgtgcagg ggcccactgg gtcactggta ctggttgggg gaggacagcg    480
 tgttgcagcg gctgtgcgac atgtcctcgt acaccacaca tgccgccgaa ttcttatccc    540
 gccacgagca cagtttcttt atctgtgtcc tcgccagcac acacgccacc cccaggccca    600
 gcccgaggag gaaggagatc accgccaggg ccgcagggag ggcagaggct gctggcgggt    660
 cagggagggc agaggctgtc tgcgggtcag ggagggcgga gcctgtcggt ggggcaggga    720
 gggcagaggc ccttggtggg gcgtccgagc atctgtgcca tccttgggac tgttcctctg    780
 tcaccaggac cagggtgccg gagccgtaga cattgacctc cgtgatggcc tggcaggtgt    840
 aggtgccagt gtccgacagc tgcaggcggt gcatggtgat agtcaggttg tcctgggacc    900
 ctgagaagtc gatgcggccc cggaaccgtc tgtccgtagt gggcaccacc ccgtcctcgt    960
 agtaaatgat gtcttggggc tgtggcccga gctgcctcag gtagatccca cgcaggcccc   1020
 cgctggtgga gcaggtgatg ttgacggagg ctcccacggg gacagtcgtg cagtggggag   1080
 actgctgcac ctcttgggca gccagggccc caggcaggcc gcgagccagc gccagaagca   1140
 ggggcagcag caggagcctc ggaggcccgg ccatgttccc cacacccagc tctcccagcc   1200
 gggcgagtgc agctgagcct ctctgggtct a                                  1231



      <210> 2456
      <211> 1100
      <212> DNA
      <213> Homo sapiens


      <400> 2456
 tcaagacctt ttaaaaatgg aactgtcggc tgcggctgga aggcgcaggc aggcgccctg     60
 gagagaattc acagggaggc acaggacaga acgctcccag gaacgaggaa gcacccccag    120
 aaaggagcgc tctatgggct ccaggcagcc gaggaaacgc gaacgtgagc cccgtgactg    180
 cactcccacg tgcaccaacg ctgccagtgt gagcagaagc ggagcccgca gagcgccagg    240
 ctgcgccggg agatgcatca cgatgaaaaa ctgcgccaga gcatggcggg aactttccga    300
 gagggcgtgt tgtttccagg cggttccacc ttctaatatg aaacagtctt ggttgatttt    360
 ccttgatact actttatgct cggcctggtt gttggcaagt agctgcccgc gtctgtacgc    420
 gcccttgatt agtttccact gcatgtgttt taacacagtc ctcctttttc cacgtttatt    480
 tgggccaacc ctgtctgcaa agatccagtt taataacaga tttgagtcta acgtgctata    540
 gccctggaaa tgtactaaag acactacaac atattggctg gaaagaatag aaatctttaa    600
 ttcctgaatg caaagcggac acacacacac acatacacac acactgtgcg gtcctcctta    660
 aggggacgaa gggagtgctc atactgagct tccctcttgg agaacgcaca cagcacaacc    720
 tccgatgggt tttcctctcc tgggggcagc gcactgccct gcgttgttgg agatgctgtc    780
 acagttggtt ctggatgtgc cactgaaatg ccaccatacc aagggctgaa actgtcacca    840
 gcaatgttga cacagctgca cagcttccat tggcagaact tgaatggtgt ctgggtgaca    900
 gcagctctga gccagcccgg tgctaggtga tgggcaactg cagtgcccat gccacaggct    960
 gggtcagatt ttcttgtggg gacgcggtca tggggatgtt gcttgtccag cttagctccc   1020
 atgtgtcctg gatgatggag gtgatgtgtg ccttctagac cggggttgag tcctaattgc   1080
 tctaagtcag ccatggccat                                               1100



      <210> 2457
      <211> 530
      <212> DNA
      <213> Homo sapiens


      <400> 2457
 attctctggt cattgagcat atccaagtga acaaagcacc taagatgcgc cgccggacct     60
 acagagctca tggtcggatt aacccataca tgagctctcc ctgccacatt gagatgatcc    120
 ttacggaaaa ggaacagatt gttcctaaac cagaagagga ggttgcccag aagaaaaagt    180
 tgaggagctc aagctttggg aaaaatgcgt gcattccttg tatcgtcatt ccagttctgc    240
 tctggatcta caaaaaattc ctggagccat atatataccc tctggtttcc cccttcgtta    300
 gtcgtatatg gcctaagaaa gcaatacaag aatccaatga tacaaacaaa ggcaaagtaa    360
 actttaaggg tgcagacatg aatggattac caatcaaagg accaacagaa atctgtgata    420
 aaaagaaaga ctaaagaaat tttcctaaag gaccccatca tttaaaaaat ggacctgata    480
 atatgaagca tcttccttgg aattgtctct gacctttcta tctgagaccg               530



      <210> 2458
      <211> 2139
      <212> DNA
      <213> Homo sapiens


      <400> 2458
 aagttactca ttgtgactgg ttgtcttgct ttcctcaggt tttcttccac catctgtgac     60
 agcttcttga tctgtctcca ggtgggtggc tgtgtttgac aggtgttgct cgtgacagtt    120
 ggggtcttcc tcagcgtcag tctggacatg gctgcaaccg ggggtggggg tggggtccac    180
 agtttcctcc cggaatctct tcctcagcat ctggctcatg ataaggtttc aggtgtcttg    240
 atggtatcca aatcggctgt tgagtcagtc ctggagaaac acaagcataa cctttacccc    300
 aagttattat tttacctatt tcctaacttt ttgttattgg atctctccac caaactagtt    360
 gttctgcttc tgtctttgca gctggtttct gtagatgctg ttcagctact gataggatct    420
 ggcctttagg caggctcaaa aaatttaaag ttaacaatgc tagattcagt tgcatatggg    480
 gtgtccccgt agtccttgtt ttcccccctt ttttttgctt tttgcaactg ctgtttcagg    540
 ggagagattc attctttcca ctatggcttg tccttgagaa ttataaggga taccagtaat    600
 gtgtttaata ttccgtatag agaaaaatgt agctagagct tggctagtat agcctggggc    660
 gttatctgtt ttaatagaag ctagaatgcc aattaccaca aaacactgca aaaggtgacg    720
 tttaacgtag gcagaagact ctcctgattg gcatgtagcc cagacaaagt gagaaaaggt    780
 gtccacacat gcatgtacat aagctagtct cccaaacgag ggaacatgtg tgacatccat    840
 ttcccaaaga gaattaggtt ccagtcctct aggattaact cctcctgtaa aagatgagga    900
 atgtaccact tggcaagttg ggcatcgctg gataatagct ttagcttctt tccaggtaat    960
 gctgtatctg tgtttgagac cagaggcatt aacatgggtt aaactgtgaa agtgtctagc   1020
 attagatact gcagtagcaa ctaggcgatc agccatttga ttcccttcag tcaaagatcc   1080
 tggaagatgt gtatgagccc ttatgtgagt gatgtaaaat cggtgcattc tacttctaac   1140
 tgctgtttgc aattgggtaa ataaagtcat cagtttttct tctgtatgaa atcgtaactg   1200
 agcattttca attaactgtg tggaatgaac cacgtatgaa gaatcagaaa tcacattaat   1260
 aggcatatca aaagcagtca ataattcaat tacagctaca agctccactt tttgagcaga   1320
 agtatagggt gtctggaaaa ctttacgttt tgatccaaaa taagatgctt taccattact   1380
 agacccatct gtaaaaacat tctcagcacc ttcaattggt ttaaatttag ttattttggg   1440
 gagaatgcaa ttagttaatt tcagaaactg aaacagcttc attttaggaa aatgattatc   1500
 gagaataccc acaaagtcag ctaaatgggt ttgccaagta agactattta taaaagcttg   1560
 ctgtatttgt gccttcatga gagggacaat aatttttcca ggatcatatc catgtaattt   1620
 aacaatccga gttctcccaa ttcctatcat agtagtgatt tgatctaaat aaggagttag   1680
 agtccatgaa tcagtatgtg gaagaaaaaa ccactctact aagtcctgtt cttggacaat   1740
 aacaccagta ggtgaatgct gagttgaaaa aattagcaaa tctggaatct tctctggatc   1800
 tattctattt atttgagctt tatggacttg cttttcaatc agctgtaact ctgcctcagc   1860
 ctcctttgtt aattgccaat ggctagtgag actaggatct cctccagtgt cctccagaaa   1920
 agaaagatct ggagggtcag gccactcctt ttcttcaaaa taattaagag gtgcagaagg   1980
 gtagggatga acctctttct cctttgctgc gttagcttta gctggcaaac aaacctgctc   2040
 tgtcacctct tctgttactt cgttatactt tgcttcctcc tcattattag tgtgaaaagg   2100
 ttccaaggtg gaatgaacca gaacccacac ttgtcccat                          2139



      <210> 2459
      <211> 415
      <212> DNA
      <213> Homo sapiens


      <400> 2459
 gggagacagg acgacacaga tcccagcaat cggtatcatc gccccccgta cagccaagag     60
 gaaaaagagc aatgtatcac tctgctgctg agctggtgtc taggggattc ccaaggcccc    120
 cagtgcaggc cccagctgag cctgcaggag ctgcggaggg agttcacagt cagcctgcat    180
 ctcgccagga agctgctctc cgaggttcgg ggccaggccc accgctttgt aagtccccct    240
 aatgcagctg gcgctggaga tgggcagacc cccaatccct tctggccccc actaacagac    300
 cttgcccccc aggcggaatc tcacctgcca ggagtgaacc tgtacctcct gcccctggga    360
 gagcagctcc ctgatgtttc cctgaccttc caggcctggc gccgcctctc tgtga         415



      <210> 2460
      <211> 423
      <212> DNA
      <213> Homo sapiens


      <400> 2460
 aaaggatata taaacaactc attttaatta ggtatgacct tcagggtagg cttcttgtca     60
 gggcagaaca gcaccatagg catgggtttc ttctcccgac tgaatataca agacggcctc    120
 ccaaccttct ttgtgctgca atggatccca tcctatatat tattaagagc tattcccatg    180
 ctccttatac cctactttct ggaatggaaa aagctctggc ccttggctgt gctctcctta    240
 gcctggctca cctatgattg gaacacccac agtcaaggtg gcaggcgttc agcttgggta    300
 cgaaactgga ccctatggaa gtatttccga aattacttcc cagtaaagct ggtgaagact    360
 catgatcttt ctcccaaaca caactacatc attgccaatc acccccatgg cattctctct    420
 ttt                                                                  423



      <210> 2461
      <211> 533
      <212> DNA
      <213> Homo sapiens


      <400> 2461
 caccttgtct tgtctccagc cagtgggaat aaccgaggtc accataatgc catgctgacc     60
 cttccccaga gcctttggat gctcactaga agaactatct gctttgtccc caccattgtc    120
 agttgccggg gactgcttcc ctccaacccc caccatgaac ttgccagatt gatttctgtg    180
 tcgcagcaca gggtgtggcc acacccagta ggcactcaat acctttaact ggagaaatgc    240
 agagggaatg ccttcatttg gctgcctctg ctgccccctg ctgtctgaga ctggttggta    300
 caacattaaa gggctggttc tggaacttaa tggtttcggg accccttttc ttgcctaaaa    360
 attattgagg accccaaaga acatctggtt atacggttta tggctattgg catttaccgg    420
 aatataaaat taaaatggaa tgggtttgaa aaaatcctat tatttgaata aaacaataaa    480
 tgtggtggga caacacaatt ttagaaaaaa tatttcccaa aataaaaaaa aaa           533



      <210> 2462
      <211> 1587
      <212> DNA
      <213> Homo sapiens


      <400> 2462
 tcagctttgg ataagtcctc cagcaagtac tttgttgaaa gcgagaaagg cagctgcata     60
 actctccagt ccacagagct gacaaatcac tgtgtcatca aagaagaggg aatcatggga    120
 aatagcctgt ggttcaccct ctgctgattc caatttcaca ttccattcca cattgatgaa    180
 taataataat gatgtacttt tagctttgtc agaaatccta tttttgatgt cccctctctc    240
 atacttagtt aaccattttg aattccactt agtaagaaaa gtttccattt tctttttctt    300
 cgggggactt agatatgatc tgcactcttc tgactgtacc tttgctttca cgagggctct    360
 ttcccggaat gatatgtcca tacaactatt gttgttgttc ttacttttag ctcttttctt    420
 agaagcccac ttgtacccag gtttgatcac accccctact ctcctgcccc gagaaagttt    480
 cagccaaact tcgggcggcg gctgaggcgg cggccgagga gcggcggact cggggcgcgg    540
 ggagtcgagg catttgcgct gggcttcgga gcgtagcgcc agggcctgag cctttgaagc    600
 aggaggaggg gaggagagag tggggctcct ctatcgggac cccctcccca tgtggatctg    660
 cccaggcggc ggcggcggcg gcggcggagg aggcgaccga gaagataccc gccctgcgcc    720
 ccgctctgct gtgggcgctg ctggcgctct ggctgtgctg cgcgaccccc gcgcatgcat    780
 tgcagtgtcg agatggctat gaaccctgtg taaatgaagg aatgtgtgtt acctaccaca    840
 atggcacagg atactgcaaa tgtccagaag gcttcttggg ggaatattgt caacatcgag    900
 acccctgtga gaagaaccgc tgccagaatg gtgggacttg tgtggcccag gccatgctgg    960
 ggaaagccac gtgccgatgt gcctcagggt ttacaggaga ggactgccag tactcgacat   1020
 ctcatccatg ctttgtgtct cgaccttgcc tgaatggcgg cacatgccat atgctcagcc   1080
 gggataccta tgagtgcacc tgtcaagtcg ggtttacagg taggaaccca aagtgtcctg   1140
 gtggcaatct taactaccag tttaatggaa tcattgttgt gtattctggt ggcagtgttc   1200
 ctccctctgg aactaagacc tctaagccag cagaacataa tgccatggga acaggaagca   1260
 aaaattttgc tagtggaaca ctatgggtga tggtgagtgg tgccacttcc acttccactt   1320
 ccaccctttg attcctggac ccgtgaatcc tgtctatggg agaaacagta ccatatattg   1380
 gacactgatt cagagcatac acagccttct ggagaacttt gccccaggcc tgcaaagtat   1440
 tgtcacctag ttggcattgt aatcgtgact tcaaaaggcc attcaaaagc tgcttcagga   1500
 tgatagggat catggtaaga ccagtaaatt ccatgagcat gagcccactg tcacacttct   1560
 ttagccataa agtgagtggc ttggccg                                       1587



      <210> 2463
      <211> 700
      <212> DNA
      <213> Homo sapiens


      <400> 2463
 ccactgcgca gaaggagcag ctgctccgcg ccccgccgcg cctcgctgag gccgatgtcc     60
 gcagggccgc ggggaagccg agggctgccg gagaaccctg caggtgtcac tcgggacgcg    120
 gaagtgcgct tgccgaggtt tgctttacaa tacgcttgag actccccgac aagcgtaatt    180
 tggtcgagtt cgacgggaaa gtactctccc caccccagcg ccggccgcgt agtccgaggt    240
 tactgtcccc ggcgcgtcct ctgttgcccc agtccagagg ctgcccttga acccgggcgc    300
 gcacgagcgc agggcatccg aggcgacagc ccctggcacg gcccgacctg tacccagcct    360
 ggcaggaaga ctgtaatcgt gggaatacag ctacctaccc aggcaatatg aagattttat    420
 ttgtagaacc tgccattttc cttagtgcat ttgctatgac tttgaccggt ccactgacaa    480
 cgcaatatgt ttatcggaga atatgggaag aaactggcaa ctacactttt tcatctgata    540
 gcaatatttc tgagtgtgaa aaaaacaaaa gcagcccaat ttttgcattc caggaggaag    600
 ttcagaaaaa agtgtcacgt tttaatctgc agatggacat aagtggatta attcctggtc    660
 tagtgtctac attcatactt ttgtctatta gtgatcacta                          700



      <210> 2464
      <211> 2109
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(2109)
      <223> n = a,t,c or g


      <400> 2464
 ctcactctgt tgcccaggct ggattgcagt ggtgcgatct cggctcactg caacctctga     60
 ctcccgggtt caagcgattc tcctacctca gcctcctgag taactaggac tacaggcgtg    120
 agccaccaca ccctgctaat ttttgtactt tttagtagag atgggtgccg agaccagctc    180
 cgtgtgcgga gaccagctcg gttgtggaga ccctaaccca gcgttgctag aggaattaaa    240
 gacacacaca cagaaatata aagtgtggag tgggaaatca gggggctgac agccttcaga    300
 gctgagagcc tcaaacagag ttttacccac atatttattg acagcaagcc agtgataagc    360
 attgtttcta tagattatag attaactaaa atgggaaaca aagggatggg ccaaaacaaa    420
 ggtatgggcc ctggctagtt atctgcagca ggagcatgtc cttaaggcac agattactta    480
 tgctatggtt tgtggttcag gaaccccttt aagcggtttt ccgccctggg gataggccag    540
 ggtgttcctc gctctcattc cggtaaacca cagccttccc ancatgggcg ttatggccac    600
 catggaacat gtcacagcgc tgcagaggat tttgtttatg ggccagtttt gggggccagt    660
 ttatgtccag atttgggggg cctattcccc agcatatccc ccttcttgtt tttgcagggc    720
 aataaaagca aaggcagctt tatcacggtg agctacttct cgcaggagtc aggatctgca    780
 tctgcagact acacaaagac aaacaacaca gattaaaagc acaatcatca ttgaaatcac    840
 agagcttcca agtgttttca tccattttaa tgggttacta gctgctaatt tgtctgcagc    900
 tcctttaagg actccagttc ctggcattaa ggtcaggtgt gcctgggatg ctttaaatat    960
 ttgttctttt aattttgcca tatccaaaaa caagtttgta gagtgtcctt ctagatgctt   1020
 ttttattctt tcccaaattt tgatcttatt aacagacatt aatagtttcc acaaatcctt   1080
 atgtttagct tctacagtgg accatatcat ttgaggttga ggtgccacta taccgccacg   1140
 tttccagata atgggaactc ttgctgtatt tcttaccatt tctaccatct gactgttttg   1200
 ttcagaccag ctgaacatag tgtggctgtg gcacacagac tgacaggtgc aattcaagct   1260
 aaacatcccc ttaggggacc aatcaataat gattccatag gaattgttgc acagcacctc   1320
 tgcctgtttt gcaatgcaat cttcccaaac aaatacattc attatttcta gccaggtcca   1380
 attctgttta caaataggtt tttgagggca gtatacctca attacaggag cagatttatt   1440
 atggtaaata cggagaccag aaagcatgtg taactgtgtc atagagtgat tacatccagg   1500
 cattattgcc agccaagatt gataaatacg cccaataagt ataattgtcc tctgtgccag   1560
 cccttgttga aggaatactc atggcaatgg tgatcaccac tatcatagct atcattaaat   1620
 tactcattgt gactggttgt cccactttcc ttaggttttc ttctgccatc tgtgacagct   1680
 tcttgatctg tccccaggta ggtggctgcg ttcgatgggt gttgctcgtg acagttgggg   1740
 tccccctcag cgtcagtctc aacatggctg caaccagggg atcctcggga tcctcccaga   1800
 atctattcct cagcatcagg ctcatgataa ggtttcaggt gcctcgatga tatccaaatt   1860
 ggcagttgat ttggtccacg gggattgctt aagagtactc aggtgtcctc cagcttagtt   1920
 ccacgttctc caaccgtcgc tctggcgacc cttcaaccca ggttcgagcc ccatgtatgg   1980
 acaccacttg ctgagaccag ctcggttgtg gagaccctaa cccagtggca ctggagcaac   2040
 tcagcactac ctgcagcggc gcagctcctc gtgccgaatt cgtgcagccg gcgaagncgn   2100
 cgagtctcc                                                           2109



      <210> 2465
      <211> 399
      <212> DNA
      <213> Homo sapiens


      <400> 2465
 tcaatgatca tgatagttat ttagtaagaa ataatggttg ttaatcaaat acatgttatg     60
 tcttgtcctt ctctgatttt tctgacttgg attccttaat ttgcagtgat gtcttagaaa    120
 tggaaaaagt atcctctggg ctttcagact ttcagcaaca acagccagtg ggatacctct    180
 gagttcttgt gttctagtct cttgtatgtc ttgggtgtct ccagccaaaa tgcagttaat    240
 caatattcca tagaacggag cattgtcgga ggtgactgct gtcctttctt tccctggtat    300
 gtacatcatt cctgggccac acttaaggaa cagcgtcttt ttctggccca acagcaacag    360
 gaagatcatg aggactgcac aaagtttgag gtgccacat                           399



      <210> 2466
      <211> 337
      <212> DNA
      <213> Homo sapiens


      <400> 2466
 ggaggatcgc agcgcatttc ggccaagaca gcctcacacg cttcaccctt tacacgcacg     60
 gtcacttgcc ccgcgcagcc ccaccccccc cagccctcct agccctgaca cacagctggg    120
 actctcaggt ccgaccagcg gtcctgaatc cgctcccacg gcacgggaaa tccttcgtgg    180
 cgaagcagca ggtggggaag cagcagcccc tgcgctgcct catctacata gaagtcgccc    240
 tatccgtgat gtcaccgaca gtgcctttcc cagtccccgt ctgcctttct gccgctcagc    300
 ctaccaaccc gctgccggag ccggcagggg gaagtga                             337



      <210> 2467
      <211> 485
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(485)
      <223> n = a,t,c or g


      <400> 2467
 gggcgttacc cccagcttag aaccccctag ggacctancg nctanntggc tnagcacaan     60
 ccgnnggaan tnngaanang aggaggagga gccggngctg gtactgagcc ctgattagcc    120
 cgggcctgtt ccagccgcgg tcagctgccg ccgagactgt gcctgttccc aggagggcgt    180
 cgtggactgt ggcggtattg acctgcgtga gttcccgggg gacctgcctg agcacaccaa    240
 ccacctatct ctgcagaaca accagctgga aaagatctac cctgaggagc tctcccggct    300
 gcaccggctg gagacactga acctgcaaaa caaccgcctg acttcccgag gcacctgtaa    360
 tccgagctac tcaggaggct gaggcagaag aatcacatga acccgggagg cggaggttgc    420
 agtgagctga gatcacacca ttgcactcca gtctgggcaa taagagtgaa aaaagctgtc    480
 taact                                                                485



      <210> 2468
      <211> 601
      <212> DNA
      <213> Homo sapiens


      <400> 2468
 gcgcggcgcg ccagcaacac tgcacgcagg tgcgcagccg gcggctcatg aaggagctgc     60
 aggacatcgc gcgccttagc gaccgcttca tctccgtgga gctggtggac gagagcctgt    120
 tcgactggaa cgtgaagctg caccaggtgg acaaggactc ggtgctgtgg caggacatga    180
 aggagaccaa caccgagttc atcctgctca acctcacctt ccccgacaac ttccccttct    240
 cgccgccctt catgcgggtg ctcagcccgc gcctggagaa cggctacgtg ctggacggcg    300
 gcgccatctg catggagctg ctcacgccgc gcggctggtc cagcgcctac accgtggagg    360
 ccgtcatgcg ccagttcgca gccagcctgg tcaagggcca gggacggatc tgtagaaaag    420
 ctggcaaatc aaaaaagtcc ttcagtcgca aggaagctga agctaccttt aagagtttgg    480
 gtgaagacgc atgaaaaata tggttggggt caccccgccc gtgttcccga cggctgatgt    540
 ctgccacgtg cagtagacgg ttcgagcgcc tgtccacaca cacaccagta ccctgacatc    600
 t                                                                    601



      <210> 2469
      <211> 3500
      <212> DNA
      <213> Homo sapiens


      <400> 2469
 taattattgt tttctttttt ttttcaacta ataatggcct tttttattta tgtggttgga     60
 aaggttaaaa taggtgacac gtgaaaagtg ccttgcacat agaaagcact ctattaattg    120
 agggggatat tattgttact gttcattgtt agtagtagca ttaaaactga tatgattgct    180
 aatgaagaaa cagacttaaa gaggaagcaa acctcgaaca gatgccacaa taaagcaaca    240
 aaattgctga ttcttcaggg ctctttctac aggacagagg gactagagct tactctccct    300
 gaggttctct tgctgtttac tttggaagct ctgacctttc cagcagacac catcacctgt    360
 gccctgcagg gagcagagat tcggactttt taagtttccg cttctggctg ggtctgtggc    420
 ccttgtctag gctctgctaa aacagatggc aaacacggcc actcagtagg tgtctttatt    480
 catacttgtt gacatttccc atggggaatg gttgaaggga ggggcaggga gggctgagcg    540
 ggaagccacg gcttggtttt cctccatcca gtggagaaga gactcggtag ggacatgcta    600
 agtagagtga acaggggaac catcactatg tgggctgaga tgcactgtgc agtgacttca    660
 gacaacctga gtccttctgt caggaaatgc aatttctaag tggaaaaaaa aaacaagacc    720
 caaagaaaaa aacaaagtgc atacaaagca aactgctaat gtaagaaagg ttctaaggca    780
 gccagcagtg aaaagccagg ggtctggagt ggccacctgg ccatgccctg tcccactgcc    840
 ctgtgccagg ctgtcgggcc accagtgccc tcttgagaca gtctccattg gctccaaggg    900
 ttctgtgagc cacagaaggt tgtgaaagga gaagagcctg aagtgtggca gcaccagggc    960
 agcccaaagc agggctgcgt tgaaaatatc aaagtatctc tttaggggtg gctctgaggg   1020
 ttggtgggat tggaggggga aggggcgcct gggaggagta cagtcagcat ctattcttgg   1080
 gcaccgggag gagccactct ctggaatctt aaattaccag gtaggagtga gaatgctgat   1140
 tagctgtaga gctgaaggca cggctgccag gcccctccgg gtccttctct agttctccag   1200
 gcccggtgta tcgaaggcag tggagaggaa gggcctgtgg gagccagggc cagctcagca   1260
 gcctagccag tcggatttga tgcttccaaa cttcacgctc ttcagacttt ggttctccag   1320
 cttcaggtaa taggcaccct tgaagaagta gctgtgaccg ccgccctgca ggtccacgac   1380
 ggcatccagg ttatcgggga tggcattcca ggcatctgcg atgagcttgg ggaagccagg   1440
 atccattttc ttcttcacct cattgtatct ccagaatttg tctccagcaa agatgtatgt   1500
 cttcttgttt ttgctccagt taaaggcggc atccactcgc tggacatcag ggggcagtcc   1560
 caggctggtc agtggcttgg ggtaccctcg ctccagggtg ctggctgagt agatccagta   1620
 ttcattccct gcaaagaaca cagccttctc ctcctgtggg gcctcgtata ccgcatcaat   1680
 cttttccggg agctcaggcc agaatgtggc caccagcagg ggccccatgg gcttgtcacg   1740
 tggcgtcaca gtccgccaaa tgaaccggtc cttgaagaag aagatctcac cacggatctg   1800
 agcgatgcca tcaaatacaa tgtcctgttt gcagatctca ggagtgacag ggcccagcgt   1860
 gggggtgggg ccggtgccaa ggtcaatgtc aggagaggcc ccatagagct cctgaatgcc   1920
 cttgatgtca tcctgggaca gacggaagtt cttggtgtag gtgtaaatgg gtgccatcag   1980
 ggccccaggg tcttgggagt gctccagccc catggcgtgg ccaaactcgt gggctgccac   2040
 gaggaacagg ctgtaccctt ggtcagggca gaagccccac ttgcggtcgt catcgtagtt   2100
 ggctgtggtc gcacaccaca tctttccgtc actgcggccg gcgctggtgc agctctcata   2160
 tttgttgccc aggaaagtga aggggaagac acagggggca ccttctgagt tcccaccaac   2220
 agtggacatg gcggtctcag ggcagaagcc atacttcttg tcgcggtcgt agtcctcagt   2280
 ggtgccgcac cagcggtagc catccgtgcg gccctcagtg gtgcagctgt cataggatgt   2340
 gccctggaag cggaatggaa acttgcaggg ctgtccttca gcgttgccgc ccatggtgaa   2400
 cagggcttca tggggacaga agccgtactt gccatccttc tcaaagttgt aggtggtgga   2460
 gcaccagagg aagccatcgc tgcggccggt atcagtgcag ctgttgtact ccttgccatt   2520
 gaacaagaag gggaacttgc agtactcccc atcggcgttc ccatacttca cacggaccac   2580
 ttggccttct cccaaggtcc atagctcatc gtcatcaaaa tgggagtctc ccccaacacc   2640
 agtgcctggg gcgaaggcat gagccaggag tccgtcctta ccgtcaaagg ggtatccatc   2700
 gccatgctcc cagcggccaa agttgatcat gatgtctgcc tctccatcat ggattcgaga   2760
 aaaccgcagt ggggtcacat cgctccagac ttggaaggca cgagcaaagg catcatccac   2820
 tgtctctggg tccagatcag gtgtgtagcc aatgatcctg tatgtgatct ggttcttgtc   2880
 ccacttgggc ttgcgaggga agaagttgta gttggccaca tctgggttgc cgcagcgtgg   2940
 cttccgcatg gtctcgatgg tattctggtc aagatcacct gtctggggca gtccaaagaa   3000
 cttctgcatc ttctttagtg tgtccttcag cacaaacagg ttgcagctct ccttggggca   3060
 gccatagaag gtgttcaggt attgcactgc caactctttg tccgttttgg gggcgacatc   3120
 gccggggaac ttgatgatgg gcgacggcgc ggcggcggcg tggctcagca ggcagcccag   3180
 gagacagagc gccctcaggg gacccgtgag cgcggccccg ggccattagc gcctccatcg   3240
 tagcgctccc tggccccgcg cgtcgcccgg gggtcgctgg ctcggtgcgt gtggccgcct   3300
 cgccgcctgg ttggagcctg ctccgcggcg cagggctgcg ctccgagggt ccgctggctc   3360
 ggtggcctgg ggtttgcccg gctcagcggc tcatggtccg gcccccgcgc cccagccccc   3420
 gccgccgccg ccgccgccgc aggtcctggc aatccctttg tatgtttaaa gccccagatg   3480
 cgcagcctcc agccaccgcc                                               3500



      <210> 2470
      <211> 575
      <212> DNA
      <213> Homo sapiens


      <400> 2470
 gatgcggttg cgcgcgtacg caagcttgga ttctgtagag cggccgctgc ggcgaactgt     60
 ccagtgctga aaacggatgc ggcccgtccc gcagagctca gacccaagcc tgccgcaccc    120
 agcggagctc gaaccgagct cctggaagcg ctgacgcaga gcgcagggag agccggagcg    180
 gcgagctcca agcctggcat ggacctgcag agacccgatt cctaccaggg aggagctggc    240
 cctgacttca acgaccacgt cctgcataag ctctctctct attgttccct tccagaccat    300
 cctggtgggt gacagtggtg tgggaaagac gtctctgctg gttcagttcg atcagggcaa    360
 gttcattccc ggctccttct cggccactgt gggcatcgga ttcacgaaca aggtggggac    420
 tgtggatggc gtgagagaga agctgccgat ctgcgacacc cgctgggaag gaacggttcc    480
 gaagcgtcac ccatgcttat tacagagatg ctcatggcta gtttctgctg tatgacccca    540
 accaccgtat ctctttgtta cgactatcgg cgctt                               575



      <210> 2471
      <211> 207
      <212> DNA
      <213> Homo sapiens


      <400> 2471
 cggccgcgtc gacgcccaac taaagtgtgc tgcgttctct gggtcctgag gcggcagtct     60
 ggccgcagtg accagactaa ctgtgccccg gaggctgctt ggaattccac ttaacgctgg    120
 aagcacgcag acgctcttga ggcgggcagc tgcgtagcgt gtggcggagc cgggagagcg    180
 ccccccaatg tggcacctga gcgtctg                                        207



      <210> 2472
      <211> 453
      <212> DNA
      <213> Homo sapiens


      <400> 2472
 gggtgcgatc tgacatgaac tcgaatcctc tagagcggcc gatacagagc gccacccgcg     60
 cctcgggcgc ccgcagaagc cggagccagt tctcagccct gatcgccgcc agccgcccag    120
 gcttcgggga aggagggagg ggagaataat gcgcccctct ttcaataaac gccactgcca    180
 accactccaa cagacacact ttcggtcccc cgccagagct ccggtgcccc cgagtgaccg    240
 ctttctgcga tcgcgtccgc cgggaccccg tccctctttc cccttcagac ttcagggagg    300
 gggaggcgct ccgcattagc ggggcagttc agcaaccccg accccacccg cgtggctcca    360
 ggcccagggg tccgatcact tccccgtccg aggtggtgga cgccaattcg cctaaaaaaa    420
 ccctggcaaa agagcgcgga cccttcacta cag                                 453



      <210> 2473
      <211> 885
      <212> DNA
      <213> Homo sapiens


      <400> 2473
 ctaggccaca gagctagttg gtgacagcag gatgagaagc caggcctctt ggttgcctaa     60
 caaagaacgt tgcaggcgtt ccatgctgag tcgatactgc ttcttcctag atgacaggac    120
 tgtagtcaaa tagaaaagtt ggtgcccttt gcccacacat ttaggctcaa caactagaga    180
 gcttgctggg cagggatcca aattgcagga cttcaggagc tgtgggggcc ggcggctggt    240
 cacgcacagg ttctcctcag caggctcccg agtctgtttg ttcaagcagc tcaccacagc    300
 ctcctggaca cctcctccac aggactcgga gcacttggtg aacccctcat actcccagtc    360
 atacagctcg tcgaaatcct gcaggccacc aaagagccca tctgtctcgt ctgggttgaa    420
 ctcaggaatt tccccgctgc atgggcctgc ataacaggca cgctgggatg ctggcttggg    480
 cccttcacac tcgtcaatag gcaggtcagc cacggactga gagaaagaca ggagcacctg    540
 gcacctgact attcgcacct gggtccccac accacaggtg actgtgcagg ccgaccaggc    600
 ctctgggatg aacctgcagt cggcaagcaa acaagaggac aggatgagaa gccccaggca    660
 ggaagccatg ggggctggag tcgtgctgca gaggcatgca aacctggctc cttaaccttg    720
 actttggcag acaatgaaag aactgataag aaggcatcac tagctcatcg tgtgtttttg    780
 ctcttcagcc cttatgaatg taactcggaa tccgtatctg cacagtactc caggaaaact    840
 ctgtcagtca ttagatttgg cttcaggatc tcaaacctgt ttgct                    885



      <210> 2474
      <211> 7268
      <212> DNA
      <213> Homo sapiens


      <400> 2474
 tgcagcctga gttgcacctg gctacagagt ggagccttgc ttctgaaaag atataaagtt     60
 tattgggcaa acctagaatc atcagtatta ttacataaat tagacagcgg taaaattttc    120
 ctagggcata tgtacaaatc acagtgattt ccattgcgca acaaacaaga ttaaaaatag    180
 gcactcccct ccctgacccc ccatgagaag gtggggtcac tccgcggggt tcccagttct    240
 ggctcgccaa ggggtgcaca aacctgccaa ggcactctgc ctgtgtgcac agcatccggc    300
 agcagtcaca ggggccccag aagcacgttg gcaacaaggc gaggctgccc agtgttcagc    360
 acaaaaaaag aattcagctg tgacagctga gcagagctca acagccatct cagagcacaa    420
 ggactgtgga aaagcttcaa atcccacctg ctaaaacaca gatgtaatgc tttttatata    480
 cagaacagac atgtccacca tggaagatca aactaagcct caacagaact tcccaacaca    540
 caacaattta cagagaaaca tgacagagca tccccgttat taggaaggac tgtactgctg    600
 ggggcaaggc agatggtttg caaagcaaac ttgattatga aaaggcttgg tgaaaataca    660
 gcccaccttc accaagacac acacacagac aggcacacac cccaaagtat ccaaatgcat    720
 taagacacct gttcatgtgc ttttcttctt gcttttaagt caatcccgtc catttaagtt    780
 atactaatta gaaggcgttc ttgcctccat cagcaagaga aaaacagtgc atcgactcct    840
 ccaatgtgtg taaaatgcat gctaggtaga ttgaaggaaa aacgagagga acccgggcac    900
 cccatttcaa atctgtacaa ctggagaaat caaaggctgc aaggactgtg tagacctgat    960
 gcaaagttaa ctggctgcaa aaataaaacc caagccagtg ctgtcttgca ctctgttcac   1020
 tcagcagctg gagcaatgaa tgattgtgac attctggtgg ggtatttgtg cagcctgagt   1080
 tgcacctggc tacagagtgg agccttggag tctttaacag tgttaagcca tagtttcaca   1140
 gttacaattg tccaaagaac tagagaccat gtaggtcaaa cacagaaatg gcgaacaaca   1200
 catcccaaac cactcaactg tttagttcca ctggtggaat ttttttttaa aattgggggg   1260
 ttaaggttgg aatttcaaat gatttggtgt tttgttgctt ttgctttttc ttcaaagcaa   1320
 acaaataaaa aggtcttgaa tatggacaga aaagaaacaa aacgctgaat gagaaattca   1380
 gtaacaagtg attttgcagt tgtttgatgg gcatggagag ggagtggggc tgaactgcat   1440
 tttgagggga tgaagcgtgc aatcttaccc actgctgggg ggtttctgtt tcttattcca   1500
 tcatgctgac agcaaatata atttgcccat cgctggctat agatatgttt aggctaagca   1560
 ggatttagac ttctgttgtg aaggaattag aagaattcag tagatacagt gtatactatt   1620
 cggttgtgac tttatttcct tcctggcttt atcaatgcct atgaaagcag gccggtggca   1680
 tttcccttca gaaaaacaac ctcttgttac ttcttgtttt aacatttcca tttcctaaag   1740
 atattctctt actgtatccc aatttaagaa aatactgcca attcataaaa ttacatggag   1800
 caaagtaaat ttgtaatgtt tttctgatac aaattttgtg attatcgtaa gaattttcct   1860
 ctacattttg cacagtgatt gtttcacgat catctatggg aacattttgg aatgcccacc   1920
 cgggtcaact atttttattt attttttttt ttattttttg agatgggagt ctcactcctt   1980
 cgccctggct ggagtgcagt ggcgcaatct tggttgactg cagcctccgc ctcctgagtt   2040
 ccatattctc ctgcctcagc ctcccgacta actgggatta caggcatgtg ccaccacatc   2100
 tggctaattt ttgtgttttt aatagagaca agggtttcat catgttggcc aggctggtct   2160
 caaactcctg acctcaggtg atctgcctgc cttggcctcc caaagtgctg ggattgcagg   2220
 catgacacac tctgccaggt aaactctttt taaattattc agtgattgtt ccatgtttta   2280
 gctcattttg attaaattaa cctctatatg acattgggac atttaaatta tgaccccgcc   2340
 atgggcagtt tccaggtagc ctgtgtctct tcaaatgctg aaatgtgtgt gacggtcaaa   2400
 agtgggttca caccatcaca cgttcttgga attgcttcta atttctcatt tgttctgtat   2460
 ggctggaggc tgatcatgat gtctgtaaag aacaaggtca ccaatgtgct tacatatttc   2520
 attttcctgc gtatcagttc acaattaagg catttcaggc tttcctgatg ctaatgctca   2580
 tctgagtatg aaatcctgga taataaaaca gacaacataa aattacacat atggactcat   2640
 gggtttatgt actttttaaa gtgtgctcaa gtgtttcatt tatggtttta ttaataattt   2700
 ttaaagtaga atgttcaata atattattac tatgatttat ttttatagtc agcaaacatg   2760
 agacttcatg cttttccttc tagctccacg tcggtgcaca gtgtaacctt tttttaaaaa   2820
 aatatggaat gctgcatgaa tctgcggatc ttcctcgcgc agggggccat gctaatctcc   2880
 tctgtgtcat tccaatttta gtatacctgc taccgaagtc agcaacagtt tcaccttttc   2940
 acattcacag taaaactgat gggaaaccgc acgctaaatg tttaggcagc gatggccctc   3000
 aactgttaat cccaacagga tggtgagtga gaagcacagg ctgaaaatag agttgtctaa   3060
 aacatttcca catttcacca tctgaacatc attttccact gagttattaa ttgtaaagag   3120
 tttattctgc tgaacctact aattattctc acctactgag ttgaccgtca cgtgaagaaa   3180
 aggtcactga tgaaacaggg tggctatgtt ctgtttctgt aatttcactg ttttaacatc   3240
 ttttttttta tatagagatg gggtctcgct atgctgccca ggccagtctc aaactcccag   3300
 gctcaagcaa tctttctgct tcagcttccc caaatcctag gattataaaa gtgagcccta   3360
 caaccagctt cactgtcttt taaagcctta aagtggacgt tctcttcata ccaccttcaa   3420
 aagcaaaaag ccattgaggt tttttgggtt tttttttttt tttggaacag ggtctcactc   3480
 tgtcacccag gctggagggc aatggtgtga tctcagatca ctgtggcctg gacctcctca   3540
 ggctcaagtg atcctctcat ctcagcctcc tgagtagctg agactacagg catgctccac   3600
 catgcccagt taactttttt gtattttgta gagatgaggt gtttcccaga caggtattga   3660
 actcctgggc tcaagcaatc ctctcgcccc agcctcccaa agtgttactt aggattacag   3720
 gtgtgagcct ggccccagtg ccttcttatc tgtaggcgaa ctctggccca aatctgatta   3780
 catttccctt gacattttgc ctacattttt aaaaatgtat ggcttttcct aacagaaact   3840
 ctccacagta ctgatgtgtg atatgtgtgc agaagagagg tagcaagtgc tagagggaga   3900
 aatctcttcc cagatattgc ttggaaaaac agctccaata gcaaggaatg caccggatgg   3960
 ctccagagaa cctgagctac tgagttttga gaagagatta ggagccgagg ggacccaact   4020
 ggcttctcac tgcacacatt ttcactaaca catggcaagg gtatactcca cccctactct   4080
 gggtgcagaa ggagacagat gaaggcaggg catgagaaaa agaagaggtg gagaagaaag   4140
 tcttggaggt ctgtgtgagt gtacccctgt tgtcaacaag gaattcctgg aaggctccaa   4200
 aacctacttc ttcaatgcac tcacccctgc cacagctggg ccctgtgacc tcatacacag   4260
 cagatttgag caatgccata tttgaggtga gtcacagtaa agagaaaagg tgcaccctct   4320
 tcagatgtct acagccaagt ttccagccag gatggtccag agaaaaagca agggagaaaa   4380
 tgagttatgt acaaagccag accccacacc ctcagtttat gctgtgtcta gcatgaccca   4440
 catttagcaa gagatgtttc agaacaaact cactgtatgg ctgtcatgcc atcaacaccc   4500
 agggaagaac atctgggggt tgctcctttc aggtgtctcc ccagtcattt cccaagagaa   4560
 cactctcacg cctggattat tctgcataaa acagcatgac ttgtcgagga gagtattagg   4620
 cacactcaac atgaatattt aaaaggagaa attaggaaca ggtgaggttc cttttgactc   4680
 tgccacccac tcacatccta tagatcatct gtttctcgct tttcccaaaa ctaaaggtga   4740
 aataaaatct ctgcatgaag gtcagcctta tagatgagct gatcttaaaa gttatttgtg   4800
 aactgtggga ggtgtatttt ttcaaaaaat ttcaactggg actttaatag gtagccattt   4860
 ccctgtgcag gatgaatttt ttttttaata cagggtcttg ctctgtcgtc cagcctggag   4920
 tgcactggca caatcagggc tcactgcagc ctcaacctct tgagctcagg caatctctcc   4980
 tacaacagct cctgaatagc tgggactaca ggtatgcaca atgacacccg actaattttt   5040
 ataatttgtg taaattccat acagacaggg ttcactatgt tgcccaagct ggtctcaaac   5100
 tcctggcctt aagcaatcct cccaacccag gttcccagag tgctgggact acaggaacaa   5160
 gccactgcac ctagcctaga tgaaattttt taatgtgaca caggttttct gaatacaatg   5220
 cattgctcca acaacttcaa agtcattgtg gattcctgca ataaattcgc tcccacatct   5280
 tctccatgtt tcrtctttta aagtcrcaag ttactaggta ggaagaacta aagatactga   5340
 atgtagacac ccccggcccc cggatatctt attcccccaa actatacaat gcatatgaga   5400
 tgattttttt aaaaatgcat gcaacatacc cttcagatgt tgtccccaag agaagggaag   5460
 ataatttgag aaactgaatt gaaaaataaa aataataggc tctgtgaagt atgtatattt   5520
 acatcactgc acaatttgtg catctgccat aatgacttct atatatacac acacacacac   5580
 acacacaatt tgtggttata atcaaataag tccagttcaa acttataaag tctatgagaa   5640
 aaaccaagac aacaccaaaa gataagataa aatctataac gaaacaattt tcaaaacctt   5700
 cctacagtgt ggaattctgg ttgcttaaat aatgccagtt ccatgaattt caactgtgct   5760
 ctgatctatt tctatacaca caggtacaga gaaaactgga aatgtcctca ggccgtgaag   5820
 aagacatttt gcttctggtc tgcttaggtg cagttctttg ttccaggcag attccaatct   5880
 tcctgtttct tccagatgtg agctcgtcct cagaaattct tgaagatttc taaatccttc   5940
 tgcggcacgg gcgcggctgt gtcccagtca tgctcagggt aagtttcgaa gttggaagtg   6000
 tcgccgttgc cagctatcgt gggcacgatg ggaggcttca gttttctctg cggaacagct   6060
 ttccagtcca cggagcggaa ccaccgatgg tggttcacat cattcgcccc gtttttacat   6120
 ggaaatccaa atgtctgggg aaatatagtt tgcctgcaag aattttctga taaatgccaa   6180
 acgggttgtc atcaaaaaat ggaggaaacc ccgaaagcat ctcgaatatc aggatgccga   6240
 gggcccacca gtccacggcc cttccgtggc ccttgctctg aatgacttcg ggggctaggt   6300
 actcgggtgt tccacagagg gtccaagtcc tgtctaccag cttcttggca aacccaaagt   6360
 ccgtgagctt gatgtgacca tccctatcca gcaggatgtt ctccggcttc aaatccctgt   6420
 agacgatctc cttggagtgc aggtactcaa tggcacagat gatctccgca gagtagaaga   6480
 gccccgtggt gctggagaag tgcccccggt tgcgcaggta gctgaagagc tcgccacccg   6540
 gcacatactc catgagcatg tagaggaagc gctcctcatg ccacgtccag aacagcctga   6600
 tgaggaacgg gtggctgact tccttcagga cagacttctc attgtgcacg tgctgctcct   6660
 gcttccggcg gatgacgtcg ggaatgctca tcaccttgag ggcgaagaaa tgcttggctg   6720
 tcttctcctt caccaggtgc acccgcccga acgtcccagt gcccatggtg accagcgcgt   6780
 cgcagtcctg caggcggtag gcaggcgcct ccggcgaccg cgcctcgggg ctggggcaga   6840
 gcgcgggcgc ccagtcggcg gcatcctccg tcacctctcg ggagttgctc tccgccgcgg   6900
 ccgcctgggc cggcccgggc gcctccatgg ggaggcactc aggtccgggg cgccgggcca   6960
 ggccggagcg ctcgggaagc cggactcccc gggacgcagc ctcggagggc ggcgcggcag   7020
 ccgcggcagc atcaacggag gctccccatg cgcgccctcg cctctgggtg cgcggctcgg   7080
 cacggctgac ggagacacag agacaatggc tgggcggtgc tcacggcact agcagcaata   7140
 gccccgggag ggagcagccg ctggcctcgc ggggcgtgca ccgagtgctg gatggctgcg   7200
 aggaaggcgg gggcccaagc attcccggtc tcacgcccgc cgcttcctcc agctcggtgg   7260
 ccgcgtgc                                                            7268



      <210> 2475
      <211> 1143
      <212> DNA
      <213> Homo sapiens


      <400> 2475
 ttataggaca tgggaaggtc ccaatactaa cagtagaatg cttaggactc taacaggttt     60
 tcggactgca tcagtaaggt tagccactaa atccgatttt tcttggtcct cttgtggtct    120
 tcctcggttc tccttgtggt ctgggaggag actagtgttt ctgctgctgc gttggtgaga    180
 gcaattattc caatcagagg gtccagggac cgttgcgggt tcttgggcag gggttgtttc    240
 tgctgcgtca gtgagcacaa ctattctgat cagcaggggc cagggaccat tgcagttctg    300
 tttggtcagg cctggcccaa tatctaggcc aattctcaag tccaggcact ggcccaagat    360
 taggccactt ctcaagtcca ggcactctgg tccttcagta tgtggatgat tacttttggc    420
 taccagtttg gaagcctcat gccagcaggc tactctagtc tcttgaactt tctcgcttgc    480
 cacactcgaa ttcttgctgg gcctcagccg cctccccgtg gggcaggctt gggacctgca    540
 gcccgccatg cccgagcccc actgtggtgg gctccgtgcg gcccgagcct ccctgatggg    600
 cactgccccc tgctccatgg cgccggtacc atcgacaacc caagggctga ggaatgcagg    660
 tgcatggcac gggctggcag gcagctccac ccgtggcccc agcgcgggat ccactaggtg    720
 aaccagctgg gctcctgtgt ctagctcagg gattgtaaat gcaccaatca gcaccctgtc    780
 aaatggacca atcagctctc tgtaaaactg acctatcagc tctctgtaaa acgaccaatc    840
 agctctcgtg agagcccgca gttcattctc gaagtcagtg aaaccaagaa cccaccaatt    900
 cttccacatg ttcaacatcg gccccgcgcg ggacggtccg ccgcctccct ctcctgctcc    960
 ccacggaccc ggaacacttc cgtaccgggg cagttccagg ccggggtcac cgccgccccc   1020
 gcctcgaact cccccagtca gctccttcct ttgccacagc agcggcgcgc cggtgacacg   1080
 tcgagacgcg gcagcacagg cgcacctgct ctgctctcgc ttcccttttt ccttcatagg   1140
 cat                                                                 1143



      <210> 2476
      <211> 784
      <212> DNA
      <213> Homo sapiens


      <400> 2476
 atgactaaaa ttcaggaacc ttctacctca gtaaaatttc taggggtcca gtggagtggg     60
 gcctatcaag atattccttc taaggtgaag gataagttgc tgcatttggc ccctcctaca    120
 accacgaaag aggcttattt gggactattg gattttggag gcaacacatt cctcatttgg    180
 tacagaacag gagaagactc tacaacacgt ccaggctgct gtgcaagttg ctctgtttct    240
 cgagccatat gacccagcag atccaatggt gcttgaggtg tcagtggcag atagggatgc    300
 tatttggagc ctttggcagg cccccataag tgaatcacag tggagacctc aaggattttg    360
 gagcaaggcc cttccatctt ctgcagctaa ctactctcct tttgagagac agctcttggc    420
 ctattactgg gctttggtgg aaactgaaca tttgactatg ggtcatcaag tcaccaagca    480
 acctgaactg cctatcatga actgggtgct ttctgatcca tctagccata aagtggggtg    540
 cgcacagcag cattccatca tcaaatggaa gtggtatata tgtgatcggg ctcgagcagg    600
 tcctgaaggc acaaccaccc ctgtcatcac ccaatgggcc catgaacaaa gtggccatgg    660
 tggcagggat ggaggttaca catgggctca gcaacaggga cttccactca ccaaggctga    720
 cctggctaca gccactgctg agtgcccaat ttgccagcag cagagaccaa cactgagccc    780
 ttga                                                                 784



      <210> 2477
      <211> 1413
      <212> DNA
      <213> Homo sapiens


      <400> 2477
 atggcccgcg ccacgctctc cgccgccccc agcaatcccc ggctcctgcg ggtggcgctg     60
 ctgctcctgc tcctggtggc cgccagccgg cgcgcagcag gagcgtccgt ggtcactgaa    120
 ctgcgctgcc agtgcttgca gacactgcag ggaattcacc tcaagaacat ccaaagtgtg    180
 aatagccaca ctcaagaatg ggaagaaagc ttgtctcaac cccgcatccc ccatggttca    240
 gaaaatcatc gaaaagatac tgaacaatcc ctaatgggct tcagacctga aaaatgcaat    300
 gtctggtttg ggcactttgg gcctgtaagc cttcttggtg aagagcagaa actttgcagt    360
 aacaccttca ttcaggaacc cgcgaccgct cgcagcgctc tcttgaccac tatgagcctc    420
 ctgtccagcc gcgcggcccg tgtccccggt ccttcgagct ccttgtgcgc gctgttggtg    480
 ctgctgctgc tgctgacgca gccagggccc atcgccagcg ctggtcctgc cgctgctgtg    540
 ttgagagagc tgcgttgcgt ttgtttacag accacgcagg gagttcatcc caaaatgatc    600
 agtaatctgc aagtgttcgc cataggccca cagtgctcca aggtggaagt ggtagcctcc    660
 ctgaagaacg ggaaggaaat ttgtcttgat ccagaagccc cttttctaaa gaaagtcatc    720
 cagaaaattt tggacgggcc tatccgggga gtgaatcctc tcagctgcaa gtctgggacg    780
 ggacttcatc ctactagagc cctagctgat tgcttgatag ttctttggtt tacaccacag    840
 ttgacatcca taacaggaat gtctgactta aagattcatt tgttactggt caatgcatct    900
 aacattgagt tttacggaaa acccctgata cttaatgaca gagagaagta ttctctgact    960
 tttctgagtg agtcaaatac cactatggaa gtaggttatg aaatagattt agagagttat   1020
 gagcagaact tttttaaaag ggaaatagaa tggaatagaa aattttcctc ccacactgat   1080
 ttacctgcta cacaaaatta ttcttactgg gcttatgtgc cttttcctcc acttattcga   1140
 cctctcacct ggatagatgc tcctgcagaa atctacacta acgatagtgt gtggatgcct   1200
 ggagccacag atgactgttg ccctgctcaa ccaggagaag gcactgcatt taatgttacc   1260
 atgggttata aataccctcc tctgtgcctt ggacatgcac ctggttgtat ccatctagaa   1320
 actcaagtct gggctgctta tcttccggag atatcagcta cagaggaacc gggatatttg   1380
 atctctggcc tctccctttc tcctttaaaa taa                                1413



      <210> 2478
      <211> 1239
      <212> DNA
      <213> Homo sapiens


      <400> 2478
 atgctgattg gatccagtga gcaagaagta gctaacacac tggacttatt tgtgagacat     60
 ttgcatgcca gagaatggga aataaaactg actaaaattc agggaccttc tacctcagta    120
 aaatttctag gggtccagtg gtatggggcc tgtcaagata ttccttctaa tgtaaaggat    180
 acgttgctgc atttggcccc tcccataacc aagaaagagg cacaatgcct actgggccta    240
 tttggatttt ggaggcaaca cattcctcat ttggaattgc ctatcaagaa ctgggtgctt    300
 tctgacccat ctagctataa agtgggttgt gcacagcagt attccatcat caaatggaag    360
 tggtatatat gtgattgggc tcaagcaaat ccagaaggca caatcaatgg tttggctcga    420
 tggtcaggga cttggaagaa gcacaattgg aaaattggtg acaaagaaat ttggggaaga    480
 ggcatgtgga tggacctctc tgagtggtca aaaactgtga agatatatgt atcccatgta    540
 agtgctcacc aacagatgac ctcagcagag gaggatttta ataatcaagt ggataggatg    600
 acccgttcta tggacaccac acagcctctt tccccaacca ctcctgtcat cacccaatgg    660
 gcccatgaac aaagtgacca tggtggcagg gatggagatt atacatgggc tcagcaacat    720
 ggacttccac tcaccaagtc attcactttt gctaaagaag tgtggcagtg ggctcatgct    780
 catggaattc actggtctta tgttccccat catcctgaag cagctggatt gatagaacga    840
 tggaatggcc ttttgaagtc acaattaaaa tgccaactag gtgacaatac tttgcagggc    900
 tggggcaaag ttctccagaa ggctatgtat gctctgaatc agcatccaat atatggtact    960
 gtttctccca tagccaggct tcatgggtcc aggaatcaag gggaggaagt ggaagtggca   1020
 ccactcatca tcacccctgg tgacctacta gcaaaatttt tgcttcctgt ttccacgaca   1080
 ttacattctg ctggcctagg agttgtgtat gggttcaagt tgacaaggga tggacttgtg   1140
 atggttaata ctgagtgtca acttgatcgg attgaaggat gcaaagtatt gttcctgggt   1200
 gtgtctgtga gagtgtcgcc aaaggagatt aacatttga                          1239



      <210> 2479
      <211> 714
      <212> DNA
      <213> Homo sapiens


      <400> 2479
 gtagaaggcc cttcattgca ctctgtcttt ccaatgttgc ttttatgctt ccctggcaat     60
 ttgctcagtt tatacttttt acacagatag catcattatt tcccatgtat gttgtgggat    120
 acattgaacc aagcaaattt cagaagatca tttatatgaa catgatttca gttaccctta    180
 gtttcatttt gatgtttgga aattcaatgt acttatcttc ttattattct tcatctttgt    240
 taatgacgtg ggcaataatt ctaaagagaa atgaaattca aaaactggga gtatctaaac    300
 tcaactgctg gctaattcaa ggtagtgcct ggtggtgtgg aacaatcatt ttgaaatttc    360
 tgacatctaa aatcttaggc gtttcagacc atatttgcct gagtgatctt atagcagccg    420
 gaatcttaag gtatacagat tttgatactt taaaatacac ctgttctccc gaatttgact    480
 tcatggaaaa agcgactctg ctgatataca caaagacatt attgcttcca gttgttatgg    540
 tgattacatg ttttatcttt aaaaagactg ttggtgatat ttcgcgtgtt ttagctacaa    600
 acgtttatct aagaaaacag ctccttgaac acagtgagct ggcttttcac acattgcagt    660
 tgttagcatt tactgccctt gccattttaa ttttgaggct aaagctggtt ttga          714



      <210> 2480
      <211> 702
      <212> DNA
      <213> Homo sapiens


      <400> 2480
 atgcgcttcg tcatgtctgt gacgatgtat cacacgacgt tggtggggtt ggatattaaa     60
 cacctcaacc tggagtctgg taaagtgtgg gttatgggaa aagccagcaa agagccccgc    120
 ctcccgattg gtcgcaacgc tgtggcgtgg attgagcact ggcttgattt gcgcgacctg    180
 tttggtagca aagacgacgc gctttttctg tcgaaactgg gcaagcgtat ctccgcgcgt    240
 aatgtgcaga aacgctttgc cgaatggggc ataaaacaag ggctgaataa tcacgttcat    300
 ccgcataaat tacgtcactc gttcgccacg catatgctgg agtcgagcgg cgatcttcgt    360
 ggtcttttcc gctttgtaag cgcaaaacgg cacgcgaaag gttccaaagt tgggtcgccc    420
 ataatttacg cggaccagat catcattggt gccggtcaga accatccggc ccggtggcgg    480
 ggcttacccc ggaaatcacg cttattggtc agtccttcaa acgacaaacg cagaaaagca    540
 ggcgccgcac ccgttgccgc actgcgccat ttccctccca tcagcattga aaatgcgata    600
 gtgaaaatcc agttcaggat cattcggcgg ctcaaccacc agcagttggt caaaccctac    660
 ccccaggtgc cgatcagcca ggcgacgaat cagttccggt ga                       702



      <210> 2481
      <211> 2580
      <212> DNA
      <213> Homo sapiens


      <400> 2481
 atgttcgcca ttatcagcta ctccagcctt gctgctgtac tgctgaccgc gactctgacc     60
 gccgcaggca ttatctcctt ccccgtggcg ctctgtctgg tgattggtgc taacctcggt    120
 tccggtctgc tggcaatgct caacaacagt gccgccaatg ccgcagcccg ccgtgtcgcg    180
 ctgggtagtc tgctgtttaa gctggtgggt agcctgatta tcctgccgtt tgtccatttg    240
 ctggcagaga caatggggaa gttgtcattg ccaaaagcgg aactggtgat ctatttccac    300
 gtcttctaca accttgtacg ttgcctggtc atgctgccat ttgttgaccc gatggcacgg    360
 ttttgcaaaa cgattattcg cgatgaaccg gaactggata cccagctacg gcctaaacat    420
 ctggatgtca gcgcgctgga tacgcccacg cttgctctgg cgaacgccgc gcgcgaaacc    480
 tgcgcattgg cgacgccatg gacagatgat ggaagaaaat atgcttattc agcagcttct    540
 ggtgggcgac gaagtgctac gaaagtaatg gtagttgtaa ctgacggtga atcacatgat    600
 ggttcaatgt tgaaagctgt gattgatcaa tgcaaccatg acaatatact gaggtttggc    660
 atagcagttc ttgggtactt aaacagaaac gcccttgata ctaaaaattt aataaaagaa    720
 ataaaagcaa tcgctagtat tccaacagaa agatactttt tcaatgtgtc tgatgaagca    780
 gctctactag aaaaggctgg gacattagga gaacaaattt tcagcattga agatatggac    840
 ctcggcgatg aggtctacac cgtcgggcgt ccacatccga tgatcgaccc aaccttacgc    900
 aaccagttaa ttgccgatct cggcgctaaa ccgcaagtgc gcgtgttgct gcttgatgtc    960
 gtgattggct tcggtgcgac cgccgatcct gccgcctcgc tggtgagcgc ctggcaaaaa   1020
 gcctgtgccg cgcgtttaga taatcaacca ctgtatgcca ttgccacggt gacaggcact   1080
 gaacgtgacc cgcaatgccg ctcgcagcaa atcgccacgc tggaagatgc ggggattgcg   1140
 gtcgtgagtt cgctaccgga agccaccttg ctggcggcag cgttaattca tccgctctcg   1200
 cctgccgcac agcaacacac accgtcatta ctggaaaacg tcgccgtgat taacatcgga   1260
 ttacgcagct ttgcgctgga gctacaaagc gccagcaaac cggttgtgca ttaccaatgg   1320
 tcgccagtcg ccgggcaggg aaaatggctg gcgaatcctg agctgctgga agccgatgca   1380
 gatgcggaat acgcggcagt gatcgacatc gatctggcgg atattaaaga gccaatcctg   1440
 tgtgctccga acgacccgga tgacgcgcgt ccgctgtctg cggtacaggg tgagaagatc   1500
 gacgaagtgt ttatcggttc ctgcatgacc aacatcggtc acttccgtgc tgcgggtaaa   1560
 ctgctggatg cgcataaagg tcagttgccg acccgcctgt gggtggcacc gccaacccgt   1620
 atggacgccg cacagttgac cgaagaaggc tactacagcg tcttcggtaa gagtggtgcg   1680
 cgcgtatcga gtatcccctg tgctgttccc tgtgtatggg cgcgtgtggc ggacggtgca   1740
 acggtggttt ccacctctac ccgtaacttc ccgaaccgtc tgggtactgg cgcgaatgtc   1800
 ttcctggctt ctgcggaact ggcggctgtt gcggcgctga ttggcaaact gccgacgccg   1860
 gaagagtacc agacctacgt ggcgcaggta gataaaacag ccgttgatac ttaccgttat   1920
 ctgaacttca accagctttc tcagtacacc gagaaagccg atgggctttt gaagccccgt   1980
 ttccgcccgt ggcagcggaa aattctcgac acattagcga cttatcatga gcaacatcgc   2040
 gatgaacctg gccctgggcg cgaacgtctg cgacgtatgg cgttgccaat ggaagatgaa   2100
 gcgctggtac tgttgctgat tgaaaagatg cgcgaaagcg gcgacatcca cagccatcac   2160
 ggctggctgc atctgccaga tcacaaagcg ggcttcagcg aagagcagca ggccatctgg   2220
 caaaaagcag agccactgtt tggtgacgaa ccgtggtggg tgcgtgacct ggcaaaagag   2280
 acgggaaccg acgagcaggc aatgcgcctg actctacgcc aggcggcgca gcaaggaata   2340
 attaccgcga tcgttaaaga tcgttattac cgtaacgatc ggattgtcga gtttgccaat   2400
 atgatccgcg atctcgatca ggagtgtggt tcaacctgcg cggcggattt ccgcgatcgc   2460
 ttaggcgtag gccgaaagct ggcaattcag attctggaat attttgaccg cattggcttt   2520
 acgcgtcgtc gtggaaatga tcatttattg cgcgacgcat tattatttcc ggaaaaataa   2580



      <210> 2482
      <211> 633
      <212> DNA
      <213> Homo sapiens


      <400> 2482
 tttcgtcgca atgtgggcat tgatcaagcc agctgccagg gcagcgggcg cagggcttgg     60
 gcactggagc ccagccccgg accgcacctc cagcagtgct gggtgcagaa ggcagtcact    120
 gtggcagtgg agagacagag tgtgtaccca gacacgtgtt gcttctgggg taaggttctg    180
 aaggctgagt agccagcggg atgcccggct tgctgaattg gatcacgggg gcagccctgc    240
 ccctcaccgc gtctgatgtt acctcctgtg tcagcggtta tgccctgggc ctaactgcct    300
 ccctcaccta tggcaacctg gaagcccagc ccttccaggg cctcttcgtg taccccctgg    360
 atgagtgcac cacggtgatc ggctttgagg cagtcattgc cgaccgtgtc gtgactgtac    420
 agatcaagga caaagccaag ctggagagcg gccacttcga tgcctcccat gttcgatccc    480
 caacagtcac agggaacatt ctgcaagacg gggtttccat agcccctcat tcctgcacac    540
 cgggaaaggt gaccttggac gaggatttgg agcggatcct gttcgtggcc aacctgtgga    600
 ccattgcccc tatgtataga gcagtctggg ata                                 633



      <210> 2483
      <211> 632
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(632)
      <223> n = a,t,c or g


      <400> 2483
 gaggagtttg cagttttaaa ggaatcacat taaggacact gcaaatccct gctgcggtgt     60
 gcggccccgt gcctgcctgc cttctgcggg ttcggtatga cggccccctg ggccatttgg    120
 agattcacac tcgcttaacc ataacgaccc tcgatgaacc ctagtgcgct gacggtttgc    180
 ttttttctgg gcaaacaaaa ctaggaaatg tgccacaagc cgataattga gcatgatgat    240
 tttcatcagg cgttgcacgg cccccatcca atggctgcgg gctgcattca tccgctccac    300
 aaaggctcta ggaggccctg ctgtgcgcca ggctcttgaa tgttctaaag accaggaagg    360
 cgcaagcttt agcatggaca cattcgctgt ctgctgaggg agataatgtt aggtaaggtg    420
 tgcaatacga tttgaaaagg tggcttttta tagtaaaaac caagtatatg tgtgtagggg    480
 gggatgccca cagggaagga tttcgaagac tccagaaagg acttcgcana ggaggtggcg    540
 tgctggctag aacctcggga gtagaaatct gcctggcaga agcaaggctg ctccagacgg    600
 aagggaatcc tcccgacgcc agcagcccag gg                                  632



      <210> 2484
      <211> 450
      <212> DNA
      <213> Homo sapiens


      <400> 2484
 tgtttgaact ttcgacccac gcgtccgctc aggatgaaca aacacttctt gttcctcttc     60
 ctcctttact gcctcattgc ggcagtgaca tcacttcagt gcataacatg ccaccttcgc    120
 acacggacag accgctgtag aagaggcttt ggtgtctgta ctgctcagaa gggcgaggca    180
 tgcatgctct taaggattta ccagcgcaat actctccaga tatcatacat ggtgtgtcag    240
 aaattctgca gagacatgac atttgatctc aggaatcgga cttatgttca tacatgctgc    300
 aactacaatt actgtaactt taaactctaa gatatttgcc ctcctgaggt ctcgctttgg    360
 aatgtcccca atgttgctca tccttcacac tctgctggcc cttgcttccc ttccgtgtct    420
 gtcctgacaa tacccctgcc ctcgcattaa                                     450



      <210> 2485
      <211> 412
      <212> DNA
      <213> Homo sapiens


      <400> 2485
 tttcgttgaa tagtttgatg gggcgccggg cggatgacag cgggaactgt tgtgatcact     60
 ggcggaatcc tagctacggt gatcctcctc tgcatcattg ccgtcctgtg ctactgcagg    120
 ctccagtatt actgctgcaa gaagagcgga accgaggttg cagacgagga ggaggagcgg    180
 gagcacgacc ttcccacgca tcccagaggc cccacctgca atgcctgcag ctcccaagcc    240
 ctggacggca gaggcagcct ggcgcctctc accagcgagc cctgcagcca gccctgtggg    300
 gtggccgcga gccactgcac tacctgctcc ccatacagct ccccctttta catacggacg    360
 gctgacatgg tgcccaatgg gggtggaggc gagaggctct cctttgctcc ca            412



      <210> 2486
      <211> 711
      <212> DNA
      <213> Homo sapiens


      <400> 2486
 ttttttttta ataatgttgt tttttcagtt tgtgattttc gttatttata cgaagagcga     60
 gctggttttc ttaccaaact ggaaacctag ctgtttgaac tatgatgaca tatctaacat    120
 attctacctt tttggagttt atcttgaacc aagaaaaatt atgggaggaa ataacagctc    180
 attgcttgat taatgattca aatttttaaa atgtttctca tgaaatgaaa gaatggcaga    240
 tgttaatatt gttattatct taatggccat gactcaattg accctagaat gagatttcat    300
 ttgtcacata gcatctgcaa ggctgaattt tcatgatgcc aaccaatctg gcacatcttg    360
 ttttctggca agctcttctg gcctctggca ggtttagcct aatggagcac tatccaccca    420
 acgtccagtc caacagagga atcacacatt acatgcttcc cagagggtac atcctggggc    480
 tgctttacag ctctgctggc aacacaggaa cttcccgtcc acgaagaacc cactatggta    540
 cttgaccagc aggtgggggt taccccttat ctctgaggag ccgacaggaa gaaaacaaga    600
 cgttagcaaa cgttgatcca agaggagaaa cattcagtaa gtgctgttat cacagaacca    660
 taaaaacccc tttggcagaa cccagggaag aagcaaaggg ttccgaaaga a             711



      <210> 2487
      <211> 892
      <212> DNA
      <213> Homo sapiens


      <400> 2487
 cccggaagct gggaaatgac ttattaacct tcatggcctc tggtcttctg aggaagcagt     60
 ctgaggagcc cgagttttga aaagggaagc aatcctccaa ggctgcgatt tccacagaaa    120
 tcacatgtga gccacaggtg tcattttaaa atttctagta gcaacagaaa cgaggaataa    180
 acagatggtg tttgagtcac tgaatttttg gaaggacttc aaatgtcaag cattattctc    240
 catgaacagg gtgatgaggg gtctggccat caccaccacc tgcctcctga gcatgctcca    300
 ggccatcacc atcagcccta gcatcttgtg gaatcatgct gctgtccagt atgtacacgg    360
 tcattctctt gttcaggcat gagaggtgat accagagcct tcgcaacacc agccgctccc    420
 caagagcctc cccagagaaa agggccatgc agaccagcct gtgtcttctg gaactggaac    480
 acggactacc cacccctatg ttgaggcagc ttctgacagg ccttactgct tacggtcatc    540
 ggtcatcagc ccacccgctt gcatctccag ctgcaagtca ctctgggccc agttctcaga    600
 caaggccaag tcggccacac caggggctct ctggggagcc tggaggaagg ttgactcttt    660
 agtctgctgc atctcagcca ggagttcatc catcttgaag gtctgagggg cacggggata    720
 caacgggcca actggggccc ttcatagaat acccccaccc tattcttttc cgaacctctc    780
 tccaaggctc tgaagactgc ctccgacgtc tgtctctcgc gcccgcgcca cccgtaaacc    840
 actacgactc ttcactcatt cctgcaagtc ttcactccct ctactccgat gc            892



      <210> 2488
      <211> 1057
      <212> DNA
      <213> Homo sapiens


      <400> 2488
 gagaacaacc cattcctccc tccctcaagc accttggaca atctgggagg gctccccaaa     60
 ggaggtgagc accttggaca atccgggagg gcttcctgaa ggagttgatg ccacagtggt    120
 tggctttgca aagacagcaa gctttgctca cattgctctc cggggctgga acctgggcag    180
 gcatgaggcc ccctagtcag tgttggcctc aaggtcctag tacaggtaac caatccctgt    240
 ctcacggaag gggagaattg ctgacccatg ctgtgggagt ctgcatctga aaaggtcact    300
 ggggcctgag agggcagctc ccagaacagt gtgaagtgtc caggaggcca gagacaccta    360
 taggagaacc tccagatatt gcatctattt cgtctacatc ctggttgtgt cgtgccccag    420
 ggatgccagc ctcacaccgt ggctcttccg gaaggtgtgg ggccaggcct gctgcactta    480
 ctgctttggg ctaatgattc agagagtgaa gggtgctttc tccccagagg aaggagcgaa    540
 ggcctttgca ggagatgaca cactgacgaa ggtttcccat gccctctcca agaaaactga    600
 tggacaacgg ggctgcatcc tgggcggggg cttacctggg aaccacgtgg gaccaggtcc    660
 ggagaaccat cctctagcca gctcgtcttg gcaagtgtcg tccaacccag tgctagctga    720
 tagaaccttc tgcaacgatg ggaatgttct gtacctggat aaccccctgg cacagatgac    780
 tactgggtac tggaaatgtg gccacaagga accaaatttt tcattgtgtt tcatcgtaat    840
 ttaaattcac atggccctgg gtggccagta gcgctcacat tggacaaaac agctctatcg    900
 tcatcatctg tgctctaccg gttttcttgg tggctaattt gtaaactggt tttggcttca    960
 tgcctgcgta agaactgcaa gcactagtag tttatgcctg gttttacatt ttgtgcctgt   1020
 cgaagtgaca ttataagaaa agacactata tggtctt                            1057



      <210> 2489
      <211> 704
      <212> DNA
      <213> Homo sapiens


      <400> 2489
 gagaacccca taaggtacag ctagggaaag atatcttgcg ataaataaga tttgccatgt     60
 ggaaaactga cccaccatca gtgataactg ctatggcatt ttggtaagat gctgatgcta    120
 attttggtaa caggagtgtc atctttgagg aatatgatta tgtgtgatta tattagcaga    180
 gcaaagctga agtctagtca cattgtactc tcatattgta ccctgaagca agaatatgat    240
 gacagcaggg gagtgatgaa cttggaggct agagaagagg gaagcagagg cttctactgc    300
 ctcggctgca ttgatactgg cttgcaaact cccggaggaa gaggcccatc atctgctttg    360
 gtgacttcag tgcaccttgc ttgcgaagag tacagtaagc attcatttgt taaatgaatg    420
 aataatatta acgtatggta ttattgaggt agagataagg gagatttggc ttaatcgctt    480
 gaccccaagg catacttagg aaggtattat tattattatt attttttgag atggaggctc    540
 cctctgtcac caagctggac gatctcagct cactggaacc tccgcctcct gggctgaaca    600
 attctgctgg ctaaactccc aggactgggg ttacaggcaa caccaccaac ctggttaatt    660
 tttgatttta aaaaaaaggg ttcaccttat ggctaggtgg ccga                     704



      <210> 2490
      <211> 575
      <212> DNA
      <213> Homo sapiens


      <400> 2490
 gatgcggttg cgcgcgtacg caagcttgga ttctgtagag cggccgctgc ggcgaactgt     60
 ccagtgctga aaacggatgc ggcccgtccc gcagagctca gacccaagcc tgccgcaccc    120
 agcggagctc gaaccgagct cctggaagcg ctgacgcaga gcgcagggag agccggagcg    180
 gcgagctcca agcctggcat ggacctgcag agacccgatt cctaccaggg aggagctggc    240
 cctgacttca acgaccacgt cctgcataag ctctctctct attgttccct tccagaccat    300
 cctggtgggt gacagtggtg tgggaaagac gtctctgctg gttcagttcg atcagggcaa    360
 gttcattccc ggctccttct cggccactgt gggcatcgga ttcacgaaca aggtggggac    420
 tgtggatggc gtgagagaga agctgccgat ctgcgacacc cgctgggaag gaacggttcc    480
 gaagcgtcac ccatgcttat tacagagatg ctcatggcta gtttctgctg tatgacccca    540
 accaccgtat ctctttgtta cgactatcgg cgctt                               575



      <210> 2491
      <211> 651
      <212> DNA
      <213> Homo sapiens


      <400> 2491
 tttcgtgctg ctgcttcgcc acctgctgct tcgccacgaa agagttcccg tgccgtggga     60
 gcaagtctgg gacctctggt cggaacggag agtcgcagct gtgtgttagg gctaggatgg    120
 ctccgttatg cgcgtgaggc aagtgacctt gcgtgtaaag ggtgaggaat atgaggctgc    180
 ggcggggcgg aggggcgcga gcttatactt atgtttatct gacagaagaa atgttatgat    240
 cacgaaggtg gtttttccag agcaaggctt agcagtttta ctgtggatgt gctgacccct    300
 gtgatttccc cgaatgtggg aatcttgatt acataatttg tggcagtggg gaactgtgtc    360
 tgtgtttttc cctgggttgt tgtcgtttta aaagtggatt ttgtttgctg tggaagcata    420
 tacaaggcgt tagtataaac taataaacag gtctttgttc ccatctgtaa cttactttca    480
 aagtaaagat tttgccaggt agtggttggt tctcacgctt gtaatctcag tagtctgtga    540
 gatgcattga taactttatg ttaataccgc tcgagctctg gagtttgatg tcagtgtggt    600
 caaatatggt ggacccgtct ctactaatct cttaactttt ttttttgttc t             651



      <210> 2492
      <211> 3128
      <212> DNA
      <213> Homo sapiens


      <400> 2492
 agcggccgcc cttttttttt ttttttcatt tcattcaaga gaattaaatc gtttattgat     60
 tacacatgat aatggataca caagcttcat tcccatctat aattttatct ggtaccatta    120
 ttcaatttag atatattgca taggatgtgc caacaatcac ttttataacc attccatgat    180
 tttgcttggg taatcccttt taatggtgaa cttcaggtca caacagtaac tatcagttca    240
 actacaccaa ggtttccgaa gacaatggct tctccaccca agcaggttgt atataaattc    300
 caaatagaac ctggcatcac cctgaaggaa ttctaacttc acactgttgg ggaaatttac    360
 caagatggct taagagtaga ctaactttac acagcacatt aaaaaaaaga catttattca    420
 gcgtcacgat cagactgtta catttagcaa tcaacagcat ggggtgcaaa aaaaaaaaat    480
 ctacattaaa accctttgtt ggaatgcttt acactttcca cagaacagaa actaaaataa    540
 cctgttatac aattagtcac aaatacagtc ctcgagtttt ttgcccatac acatgagtat    600
 ttgtctaaaa catgtcttct ttgtagcagc taggccctgc caccactgtg cttggctgag    660
 ttcacaaatc tgttgtaacc tgtagcttcc ctgtcacttc tctggctctc ctctcctgct    720
 aagctttgtt tcctaattaa aatcttctgc cactgccata gctactgctg ctgctggaac    780
 cgccatagcc accttggttt cgtggttttg caaagtattg gcctccaccg ccataggggc    840
 cagagcttct gcctccaaaa tttcctccct tcatgggtcc aaaatttgaa gactgattgt    900
 tgtaattccc aaaatcattg tagcttccac cacctccaaa attgcttcca tcattaccaa    960
 atccattata gccatcccca ctgccaccat atccaccacc caccacgggt ggcacccaaa   1020
 gccaaccaag gaccaactga agtttcctcc acggaccgaa gttgtccatt cccaccgaaa   1080
 accacctccc acgacccacc accaaaagtt tccaagaacc acttcgaccc tcctttgggc   1140
 tggatgaaag cactagccat ctcttgcctt tgaacagggc ttttctaaac ttcacaggtt   1200
 gtggcccatt cacagtatgg taattcctga aatggacaat cttatcccac ggagtccatg   1260
 gtccgtccaa aggttacaaa aggcaaagcc cctttttctt ggccactggc ctccggtcca   1320
 gtcaatggat ttcaatcaac ttcaaatttt tccaatactt gttcaaaata atctcttagg   1380
 tgaatgttct ttcaggggtc ttctttaatg ccaaccaaac aaaatatctt ttttcacaag   1440
 ttaatgtggg cacctgggtc ttttgagaaa tcttcctctg gaagacaagc tcctctttgg   1500
 gttcccacaa ctccttacca tcccaccttt gtgtggcctt tgcattcata gctgcatcca   1560
 cctcctccac acgtggcata tgtgacaaac ccaaagcccc ttggagcgct tggtggtttg   1620
 ggatctctca ttaccacaca ggtccgtgda gcgtttcccc cattgcctcg aaaatggctc   1680
 ctcagggctc tcatcatgtt gtttcaaagc tcraaccctc mgaatgaaga gcttcctcag   1740
 ctgttcgggg ctctttagga gactctgccc gtggacgccg ccgaagaagc atcgttaaag   1800
 tctctcttca ccctgccgtc atgtctaagt cagagtctcc taaagagccc gaacagctga   1860
 ggaagctctt cattggaggg ttgagctttg aaacaactga tgagagcctg aggagccatt   1920
 ttgagcaatg gggaacgctc acggactgtg tggtaatgag agatccaaac accaagcgct   1980
 ccaggggctt tgggtttgtc acatatgcca ctgtggagga ggtggatgca gctatgaatg   2040
 caaggccaca caaggtggat ggaagagttg tggaaccaaa gagagctgtc tccagagaag   2100
 attctcaaag accaggtgcc cacttaactg tgaaaaagat atttgttggt ggcattaaag   2160
 aagacactga agaacatcac ctaagagatt attttgaaca gtatggaaaa attgaagtga   2220
 ttgaaatcat gactgaccga ggcagtggca agaaaagggg ctttgccttt gtaacctttg   2280
 acgaccatga ctccgtggat aagattgtca ttcagaaata ccatactgtg aatggccaca   2340
 actgtgaagt tagaaaagcc ctgtcaaagc aagagatggc tagtgcttca tccagccaaa   2400
 gaggtcgaag tggttctgga aactttggtg gtggtcgtgg aggtggtttc ggtgggaatg   2460
 acaacttcgg tcgtggagga aacttcagtg gtcgtggtgg ctttggtggc agccgtggtg   2520
 gtggtggata tggtggcagt ggggatggct ataatggatt tggtaatgat ggaagcaatt   2580
 ttggaggtgg tggaagctac aatgattttg ggaattacaa caatcagtct tcaaattttg   2640
 gacccatgaa gggaggaaat tttggaggca gaagctctgg cccctatggc ggtggaggcc   2700
 aatactttgc aaaaccacga aaccaaggtg gctatggcgg ttccagcagc agcagtagct   2760
 atggcagtgg cagaagattt taattaggaa acaaagctta gcaggagagg agagccagag   2820
 aagtgacagg gaagctacag gttacaacag atttgtgaac tcagccaagc acagtggtgg   2880
 cagggcctag ctgctacaaa gaagacatgt tttagacaaa tactcatgtg tatgggcaaa   2940
 aaactcgagg actgtatttg tgactaattg tataacaggt tattttagtt tctgttctgt   3000
 ggaaagtgta aagcattcca acaaagggtt ttaatgtaga tttttttttt tgccccccat   3060
 gctgttgatt gctaaatgta acagtctgat cgtgacgctg aataaatgtc ttttttttaa   3120
 aaaaaaaa                                                            3128



      <210> 2493
      <211> 657
      <212> DNA
      <213> Homo sapiens


      <400> 2493
 tcacagtccc tgtccatcct gaaccagtcc agggccagag taggttccac tgtagaggac     60
 gaaaggcaag agcaggctgc gagccgccac gctgtgcacg gtctcagacg tgaatgacca    120
 tcctcttggg gggacccacg gcccgtccac agcgggtggg aaccgcatct gtaacaggcc    180
 caaggtgctt cctcctgcac catcaatccc agacacctgg gtgtggtgtc tgagttcaac    240
 agccagggag gggcctggac ctttcaacag acggccccgg tggccgttct caggtgggac    300
 tgatctggtc ctgctgctgc cttcactgag cagcatcggg agaaccaggt ggccgctgtc    360
 caggctctgc gctcccggcc ctgctgggtc tgctctggag ttcagggctc gtgatggtgt    420
 cccagtgtgt aggtggcccg agctgggagt cccacagtcc cgcagcggcg acgccgccac    480
 ccgccgagtg ccgaggcccg gggcccactc ccagcccagc tccaggagag gccgcgccgg    540
 aggaccgcga ggacggcgcc gcagcgccag gtcgggctga gcctgccagc atcgtggccc    600
 cagctgacgg ctcccaaggg caggtgctgg caacacaagc aggagccctc ggggcat       657



      <210> 2494
      <211> 2418
      <212> DNA
      <213> Homo sapiens


      <400> 2494
 cggagattcg tacgagcggc accatggccc cgcgggggcg gcggcggccg cggcctcaca     60
 ggtctgaggg cgcaagacgt tcaaagaaca ctttagaaag aacacattcc atgaaagata    120
 aagctggtca aaagtgcaag cctattgacg tgttcgactt tcctgataat tctgatgtct    180
 caagcattgg caggctgggt gaaaatgaga aagatgaaga aacttatgag acctttgatc    240
 ctcctttaca tagcacagct atatatgctg atgaagaaga attctccaaa cattgtggac    300
 tgtctctctc ttcaactcct ccaggaaaag aagcaaaaag aagttcagac acttctggaa    360
 atgaagcaag tgaaatcgaa tctgtaaaaa ttagtgcaaa aaagccagga agaaagctca    420
 ggcccattag tgatgactct gaaagcattg aagaaagtga tacaaggaga aaagttaaat    480
 cagcagagaa aataagtaca caacgtcatg aggttattcg aaccacagcg tcttcagaac    540
 tttcagagaa accagctgag tctgtcactt ctaaaaagac aggacccctt agtgcccagc    600
 cctctgttga aaaagagaac ttggcaatag aaagtcaatc gaaaactcag aaaaaaaggg    660
 aagatatctc atgacaaaag gaagaaatca agaagtaaag ccataggctc agatacttct    720
 gacattgtgc acatttggtg tccagaagga atgaaaacca gtgacatcaa ggagttgaat    780
 attgttttgc ctgaatttga gaaaacccac ctagagcatc aacaaagaat agaatctaaa    840
 gtttgtaagg cagccatcgc cacattttat gttaatgtta aagaacaatt catcaaaatg    900
 cttaaagaaa gccagatgtt gacaaatctg aaaaggaaga atgctaagat gatttcagat    960
 atcgaaaaga aaaggcagcg tatgattgaa gtccaggatg aactgcttcg gttagagcca   1020
 cagctgaaac aactacaaac aaaatatgat gaacttaaag agagaaagtc ttcccttagg   1080
 aatgcagcat atttcttatc taatttaaaa cagctttatc aagattattc agatgttcaa   1140
 gctcaagaac caaacgtaaa ggaaacgtat gattcatcca gccttccagc tctgttattt   1200
 aaagcaagaa cacttctggg agccgaaagc catctgcgaa atatcaacca tcagttagag   1260
 aagctccttg accagggatg agaagagcag tctactaaaa tgtgcctata ggaagactag   1320
 tctcatgctg ttaccttctg aaactgtacc tttataaatc aattgttttg caaagaagtt   1380
 atggcctact tagaatctaa aatttgttat tcaaattaaa tggctgtgaa caatgttaaa   1440
 tagcatcagt ttgtccaata gttttaaagg ccataatcat cttttctggt taatatcttg   1500
 agtaatttta aaatgttgac accttaatcg gtcccaggta tgagctataa taaacttgta   1560
 aaattaagtt gatgtgaaca taattttgat taattaataa ggcgatttct cctgaattta   1620
 caccaaagct aatttttaat gaaattgggt ttacaggaag gtaaaaaaca aaaattggga   1680
 aaggcaaagt aataaaactt agtttatata aacaggttga atgatatatt tatcaaatct   1740
 cacagacatc aggcaaatta tagcctggtg acaaaagtgt tcatagtgaa ttagttactc   1800
 ttgtaatact tctataatta gttcatcagg aatttcatcc acttcactgt tataactgag   1860
 aagactgttc tctgcagctt cagctaattc agcatcttca gtagcttcta aaaaataagc   1920
 atcatcaatg ccattatccc agacagcatc agcagatgca cctgttgaca gcctgctagg   1980
 tgatggttta tgaggattct gggtttcatt gctcctagtt tcatctgctt catctgttgt   2040
 aaactcttct tcctctttga aaaaaaacag gagacatact tcagcaggta atgggaaaca   2100
 gtcagatttg aagttttttg ctttacatac agggtcatga cattttttat accaaacttc   2160
 atttttcaga tcaaccagaa tcctttttgt ttaaaaaaaa aaaaaagtat taataccaag   2220
 actgggtaga aaacaaaatc cagctgcatg ctgttccaag aaatatgcct aagacttaaa   2280
 gatggagaaa aattaaaaag taaaaggata aggatagata cataccaatc aaaacggtgg   2340
 ttgccaaaaa tcacacaaaa tgaactgcag ggcaaaaagt agatactgat gaaagttccc   2400
 ccaggaagat gtaacaat                                                 2418



      <210> 2495
      <211> 1137
      <212> DNA
      <213> Homo sapiens


      <400> 2495
 gatacgtact gcaggggaga ccagctgcac atcctgctgg ttgtgaggga ccacttggga     60
 cgcaggaagc aatatggcgg ggatttcctg agggccagga ggtcttcccc agcgctgatg    120
 gcaggtgctt caggaaaggt gactgacttc aacaacggca cctacctggt cagcttcact    180
 ctgttctggg agggccaggt ctctctgtct ctgctgctca tccaccccag tgaaggggtg    240
 tcagctctct ggagtgcaag gaaccaaggc tatgacaggg tgatcttcac tggccagttt    300
 gtcaatggca cttcccaagt ccactctgaa tgtggcctga tcctaaacac aaatgctgaa    360
 ttgtgccaat acctggacaa cagagaccaa gaaagcttct actgggtgag gcctcaacac    420
 atgcgctgtg ctgcactcac tcacatgtat tctaagaaca agaaagtttc ttatcttagc    480
 aaacaagaaa agagcctctt tgaaaggtca aatgtgggtg tagagattat ggaaaaattc    540
 aatacaatta gtgtctccaa atgcaacaca ctgaagtcag tggatctgca tgaatctgga    600
 aaattgcaac accagcttgc tgtggatttg gataggaaca tcaacatcca gtggcaaaaa    660
 tattgttatc ccttgatagg atcaatgacc tattcagtca aagagatgga gtacctcacc    720
 cgggccattg acagaactgg aggagaaaaa aatactgtca ttgttatttc cctgggccag    780
 catttcagac cctttcccat tgatgttttt atccgaaggg ccctcaatgt ccacaaagcc    840
 attcagcatc ttcttctgag aagcccagac actatggtta tcatcaaaac agaaaacatc    900
 agggagatgt acaatgatgc agaaagattt agtgactttc atggttacat tcaatatctc    960
 atcataaagg acattttcca ggatctcagt gacattcgtc atgtcctcaa atacaatgct   1020
 tcaaaaaacg ctgctgatct tgatctcttt ttcagtagta acctggatga tttttataat   1080
 ttctcagaac ttcacaaagg taggagcaaa tcacctttga tgcagatcac acagtaa      1137



      <210> 2496
      <211> 502
      <212> DNA
      <213> Homo sapiens


      <400> 2496
 tttttggtaa taatctttta tttgagttca ttttcaaaac cattaggcct tcgtagtaga     60
 ggccccctgt aaaaccagcc cctcttgcac ccttaatgag gttagccctc tccactgtct    120
 acatacacag tataatctgg aaaaaacagt gggattccca catgtttagt gcatgaaaaa    180
 caggccagac tcagtcattt tccataattg accggggttc tgttctgttc ttttacagca    240
 agcacagcca gcatctctgc ccctctgccc tttagctcct tacattggta gggcctctct    300
 ccagtgtgaa ttctctgatg ttgcttgagt tgtgagctca ctctaaaggc ctttccacat    360
 actttgcact catagggttt ctcaccggta tgaattctct gatgtcgtat aagagttgag    420
 ccttgattaa aagccttccc acattcctta cattcataga gtttcctgcc agtatgaaca    480
 gtctgatgtt gaatcaactg ag                                             502



      <210> 2497
      <211> 2885
      <212> DNA
      <213> Homo sapiens


      <400> 2497
 atgggggaaa ctgccctcat gatccaatta cctccacctg gtcccgccct tggcacatgg     60
 ggattatggg atttacaatt caagactaac accacatcta cagacactga ccctagatca    120
 cacctccagg agacaggaga caacatctta acacttttca ccatgcatcc tcctcttgaa    180
 tcagagtgga ctatttgtaa ctttcgccag atatggctct tgtcttcatg gtccaccttg    240
 gagactagag ctcagccatt acactcctat ttcagaaagc tgaaaggaag gggcactgca    300
 attgcgggca ttgtttttgg aatagtattt atcatggggg tcattgctgg gattgccata    360
 tgcatctgca tgtgcatgaa gaaccacagg gcgacccgcg tgggcatcct caggacgact    420
 cacatcaaca ccgtctcctc ctatcctgga ccaccaccct acggtcacga ccacgagatg    480
 gaatactgtg cagacttgcc tcctccatac tcccccaccc cacagggtcc agcacagcgt    540
 tctccacccc ctccttatcc tggaaacgca aggaaataat ctatctccca gaacagaaca    600
 tgtgccaatg ggcgatcttg cctggaataa aatgcctcta ctcagaaaca ggcaggaaag    660
 aattgctcca aggaatactt tttggggtca gataatgtgt caggtggaat atccctgcta    720
 ggagatatag gatttctact ctgctcaaag ctgaccccat ctggagtatt aatgtttggt    780
 tctatgttaa ccacatttta agagatctgc tgatccacct aagcacattc agggaagagt    840
 aatgtaattg acaaaatatc tgataatcat gttgtttaag ggctaggtga agaaagtttc    900
 agtattgatc ctggaaaaaa agaagatcta agtaggatgg gagaatgatt tggcccacac    960
 aaggaagcaa ctttattcta tatagcttta aaagtcagaa ctagaattgt tcattctttc   1020
 attcatcaat aaatgtattt tgagtgccta agagtttact atgtgcctag cactgtttga   1080
 ggtcctgatg gaagttacag gatgggtact ctggttttag tacaagaaag agcaatgact   1140
 agattgcttt gtgaagctct tggtagagac acgctccaga agggataaca aaatcaaata   1200
 gtagatgggt tcattgggcc tcaaaagttc tgctcgtatt ttaggggggt gtgaagtgaa   1260
 tttctatatg tccaggagtg aatacaacag aaagagttgg atcttattta tttaattagg   1320
 gagttaaaac aagaccaaaa agactcaaca gccgctttga agccaaggaa ctctttccat   1380
 gccagctact gccacctaaa aatcatctgg ctttatagtg gatcagaata aaggttattc   1440
 taactgtggg gagaaaaaaa aaattgtatc aagttccaca ggtagcagac acttcacttc   1500
 caagtaaaag atgagaaatc aattattccc acaggatttt aggtcaggga gcaaaaatct   1560
 cagaacttga ccatgaagat acacaacaga ctcggcaaaa ataaagtggg aaatgaagtt   1620
 cagattccct tctgtagatt tcccttaaaa ctattatttt tttccttctt cgtaaaattt   1680
 tggataatct gttctcttaa aaaagttaat gacacaatta agatactgac atcaaattgt   1740
 tgccttttac caaaatgcaa attttatgaa gtgcctacct ttatatgtat aaagcattta   1800
 ataaataatt ctaatgtgcc atattttgct gtgagtgacc ttaacattta tatttttata   1860
 tgaattgttt catgtattta taaaaattgt atattgaaca ttggaaatag atgattagat   1920
 ttttgtgtca ttttacaatt aaatctaaaa tgcttaatcc aatatcatca tcaaaattca   1980
 gtgaaatccc aaaacagtgc caagaatttt gctgaatgaa acaatcaaac aaagcatttt   2040
 aaggtgtaag ttatagtacc tgtacttgca gataagaagc ttactatatc attattataa   2100
 gtagcatata ttactttcaa atacctatat tagaaagata ttggatctga ctgaaatata   2160
 acctacctgc cagtaaggtc caaaggctga atttgttttg aatgagttcc atgatcttta   2220
 agcactgatg attttcttat atatgaggat gcaaagcatt caagagtttc agcctgttct   2280
 ggtgaggggc tccctgtctt tcataaagtt ttcagtgcaa ttttaatagt acatatgctt   2340
 taatttattt ttcttctgcg tgtggtcaga cccaattaca ctgtggctaa gactctcaaa   2400
 gtgccagggt ttctgtgatg attctgagaa tgctgaatac aaatatacct tatattcttt   2460
 aaggaaaacg gaaaggaaag atcagcagaa aatagggttt tctcatcttc accatcaata   2520
 aacatttatt gcgtacctcc tatattctgc aaattttccc caaatagaag ccagttcagt   2580
 ccacaccatc tcttctttga gttgtttatg gcctccctta aggcatttta caaacccata   2640
 agcctacaat agatgagtat ttttactatt tgtattaagt gtcataatag catcaatgtg   2700
 cacattacca gtatagactg ttggagttca ctgattgttt tcatagatga tgcttcttgg   2760
 ggaaaaatag tataggatgt gaaagttttg aattacggtt atttaaaaac taacatttgc   2820
 tatggccaaa gtgtttacaa taagcaataa agtgaaagaa cctattataa cccaaaaaaa   2880
 aaaaa                                                               2885



      <210> 2498
      <211> 943
      <212> DNA
      <213> Homo sapiens


      <400> 2498
 gcggccgccg ggagggcgcg cggcgccgga gacatgttca ggcggaaaca gagcaacccc     60
 cggcagatca agcgttccct cggagacatg gaggccagag aggaggtgca gttggtgggt    120
 gccagccaca tggagcaaaa ggccacggca cctgaagccc cgagccctcc cagcgcagat    180
 gttaactcac ccccaccgct gccgtccccc acatccccag gaggccccaa ggagctggaa    240
 ggacaggaac cagaacccag gcccacggag gaagagccgg gcagtccctg gagcgggcca    300
 gacgagctgg agccggtggt gcaggaggcc ggaggcgcat acgggcccga ctcagcctcg    360
 ccacgggcct gtcctggggc ccgttccatg ggagtgtcca gaccagagcc tcatccccca    420
 ggcaggcgga gccgagccca gccctgaccc tgctgctggt ggacgaggcc tgctggctga    480
 ggacgttgcc ccaggccctg actgaggccg aggccaacac agagatccac aggaaggatg    540
 acgcactctg gtgcagggtc accaagccgg tgcctgcggg gggactcctg agcgtgctcc    600
 tcacgggcga gccccacagc acccccggcc accctgtgaa gaaggagcca gcagagccca    660
 cgtgcccggc ccctgcacac gacctccagc tcctgcccca gcaggccggg atggcctcca    720
 tccttgccac cgcagtgatc aacaaagacg tcttcccctg caaggactgt ggcatctggt    780
 accgcagcga gcgcaacctg caggcgcacc tgctctacta ctgcgccagc cgccagggca    840
 ccggctcccc ggccgcagcc gccacagacg agaagcccaa agagacctac cccaacgagc    900
 gcgtctgccc ctacccccag agccgcaaga gctgccccgg cgc                      943



      <210> 2499
      <211> 435
      <212> DNA
      <213> Homo sapiens


      <400> 2499
 tgccgtatgc aggaccagct ctgatgtaga tgacaaccct ccagttttta atcagctcat     60
 ttatgagtca tatgtgagtg aattagcccc ccggggccat tttgtaacct gtgtacaagc    120
 ctctgatgca gacagctctg attttgaccg gttggaatat agcattttat ctgggaatga    180
 ccggacgagc tttctgatgg acagcaagag tggagttatc acattgtcca accatcggaa    240
 gcagcggatg gagcctctgt acagtctcaa tgtgtctgtc tctgatgggt tgttcaccag    300
 cactgcacag gtgcatatta gggtacttgg ggctaacttg tacagccctg ccttttcaca    360
 aagcacatac gtagctgagg tgagagagaa cgtggctgca ggaacaaagg taattcatgt    420
 tcgagccaca gatgg                                                     435



      <210> 2500
      <211> 400
      <212> DNA
      <213> Homo sapiens


      <400> 2500
 ggcacgcact cccccgcgcg gcaccacttg tctgccccac actcggtgcc atccagggga     60
 gggtccagct tggtcttgca ggatgtgtct ccttctacca ggcaccacag tccagcacac    120
 attagatgct ccatgtttct gcagaaggtg gcattcatgc caaacaggat ctggcactgc    180
 tcgttggcac tgtagtgcat gcccggcagc ttgtgcggga ggcgtactgt gtgctggctt    240
 ctggggtccg tgactagcaa gcaggtgctg acttttgact tgaggaagtt ttcaaggtca    300
 tctcggctgc aggaggacca agagaggtca cttgggttcc ggcctttcac ccactctcct    360
 gacatgatgt gggacctgcc agcgcaagat gagtggtcat                          400



      <210> 2501
      <211> 397
      <212> DNA
      <213> Homo sapiens


      <400> 2501
 gccagaaaat cgacacctca aagcactagc tctttgaacc gttctctgcc tcaccctaac     60
 ttcctgcagc tttcgccagt cattggccac ttagtccttt gggggctggg cagcggctcc    120
 gtgcactttg gagtcggggg cgccttccta gagcccagca tccactgggg ctccgaagcc    180
 gtagcctgtc tgtgtcctcc acccactttg tgccctcatc ctcctctggg gctatggcag    240
 cggcgatgcc agcgtcctct gcaggtccga caggctgctg acgggcacca agatcaccac    300
 gcagaacatc cacgaccact tggttcctac ctggacaagg tgcgggctct ggaggaggcc    360
 gggtgagctg aaggtgaaga tctgcgactg ggcccct                             397



      <210> 2502
      <211> 834
      <212> DNA
      <213> Homo sapiens


      <400> 2502
 gaattcccgg gtcgagggcc agctctgcga cctggacccc agtgctcact tctacgggca     60
 ctgcggcgag cagcttgagt gccggctgga cacaggcggc gacctgagcc gcggagaggt    120
 gccggaacct ctgtgtgcct gtcgttcgca gagtccgctc tgcgggtccg acggtcacac    180
 ctactcccag atctgccgcc tgcaggaggc ggcccgcgct cggcccgatg ccaacctcac    240
 tgtggcacac ccggggccct gcgaatcggg gccccagatc gtgtcacatc catatgacac    300
 ttggaatgtg acagggcagg atgtgatctt tggctgtgaa gtgtttgcct accccatggc    360
 ctccatcgag tggaggaagg atggcttgga catccagctg ccaggggatg acccccacat    420
 ctctgtgcag tttaggggtg gaccccagag gtttgaggtg actggctggc tgcagatcca    480
 ggctgtgcgt cccagtgatg agggcactta ccgctgcctt gcccgcaatg ccctgggtca    540
 agtggaggcc cctgctagct tgacagtgct cacacctgac cagctgaact ctacaggcat    600
 cccccagctg cgatcactaa acctggttcc tgaggaggag gctgagagtg aagagaatga    660
 cgattactac taggtccaga gctctggccc atgggggtgg gtgagcggct atagtgttca    720
 tccctgctct tgaaagacct ggaaagggag cagggtcctt catcgactgc tttcatgctg    780
 tcagtaggga tgatcatggg aggctatttg actccaaggt agcagtgtgg tagg          834



      <210> 2503
      <211> 440
      <212> DNA
      <213> Homo sapiens


      <400> 2503
 ggcaatcaga aatgcacgag gaacaaccac cgcatctcct ccctgctctg cgacccccag     60
 gaaggctacc tccagatgct gcagatctcc aacctctatc tgtatgacag tgttctgatg    120
 ctggccaacg cctttcacag gaagctggag gaccggaagt ggcataacat ggcgagcctc    180
 aactgcatac ggaaatccac taagccatgg aatggtggga ggtccatgct ggataccatc    240
 aaaaagggcc acatcactgg cctcactggg gtgatggagt ttcgggagga cagttcgaat    300
 ccctatgtcc agtttgaaat ccttggcact acctatagtg agactcttgg aagagccttt    360
 cgtgatggtg gctgagaaca tcctaggaca gcccaagcgc tacaaagggt tctccataga    420
 tgtcctggat gcactggcca                                                440



      <210> 2504
      <211> 395
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(395)
      <223> n = a,t,c or g


      <400> 2504
 gngnngnagc gtctaggact gaggctcagg ggacgccggg ggccagcaca gggcccggtg     60
 tccctcgggc cgtgccggta actgggattg gcacccgccg gccatggaag agcctgggcc    120
 cccaggtggg ctcagccaag accaagtgga gcggtgcatg ggtgccatgc aagaggggat    180
 gcagatggtg aagctgcgtg gcggctccaa gggcctggtc cgcttctact acctggacga    240
 gcaccgctcc tgcatccgct ggaggccctc acgcaagaac gagaaggccg agatctccat    300
 cgactccatc caggaggtga gtgaggggcg gcagtcggag gtccttcagc gctaccctga    360
 cgggagcttc gaccccaact gctgctgtag tatcc                               395



      <210> 2505
      <211> 691
      <212> DNA
      <213> Homo sapiens


      <400> 2505
 tttcgtccaa gctggaggaa cgggaccgag ggatcgaccg aggctggctg gctaggggtg     60
 ggactggcag agctacggac aggtgggagc agtcagacag cctgagagag ggagaccaga    120
 acgcaaagag agcgagagca ttaagtaggc agggagaggc acacagaaag atagacagca    180
 acactcgcgt gctccctccc tccacacgcc ctcctcttac cgagcgaagc ggccaggggc    240
 acagagtggg agaggactgt gggcacagaa gaccggaaga gggacgctgc attgctggtg    300
 ggacggaggg attcggacgg acggacagac cagcgcacag actggcagcc tgcgagagtg    360
 gcagctttga gagcagagcg cagcaaagcg agaatcccgc gccgagctgc tagtcggacc    420
 cacagacggt cggactgaca gacgtgcaga cggacagaag agcagacagg aggcgggggc    480
 gcgttcactc ccggcggcca gccggccaga gaaggcggcg gtggcacctt ctgagcgcgt    540
 ccggagcaga gaccagcagc agcaggggca gcggggacac aagccgcgac cgagccgccg    600
 ccgcagccct ggctgccaca gctgtgtggg atcccagccg acactgcaga aagctccttt    660
 tactagcagt taaataaatc gaccaaaaaa a                                   691



      <210> 2506
      <211> 1887
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1887)
      <223> n = a,t,c or g


      <400> 2506
 tttttttaat ttcctgcaat aagtagtcat ttaattaaag aacaaaatta acaggaatca     60
 aaatgttgca gctgtatttt ttgttagaca ttatataaaa aaggaaaagt ataatacagt    120
 aaatcatctt gtataacatg aacttaaaga gttttcaaat taattatgat caggataaaa    180
 atgtcttttg aacataatac tgaatgacac tgtcacatgt ccctcatgtc agaggcctgg    240
 gagtggtgag cctgcacatg cacgttgccc gtcctccatt acactgcaga actgtaaaac    300
 aaggttgaaa ggcaaacaac agttttcttc tgatagagtt atgttgggtc ttaactgacc    360
 ccaacagttc acactcctca gacaccaaag aaggaaggaa gtgtgtcctc tggttactcc    420
 tcttgcaggt aagtgtggtc aagattgcac ctgtgtgtgt gatcctactc ttctcacaaa    480
 cacagcaggt agggtagtct tgagctgaac ttcaggaaag ttccctgatg aatgttcagt    540
 gttggtatca aaaaattaaa cacaaattct tctcagaaga aaatctctat ggcctgtgga    600
 atcttgtcaa gtgcttgctt gatgcatgta cctccatttc attacttttg tactcattta    660
 attctttacg aattgctgcc ttatctgctg ctgacagtct cgtccagggt ttgtctgccc    720
 tcctgtcata gtcctgcgct tttgctactt ccacgtaatc actgaatcgt atcagaattt    780
 ttctgtctct taattcatca acagtgggtc tctgattaag ctttcttgtc aatctttgct    840
 tgatttctct tctttcttcc tgctctgtct gatcattcct ttgtttcaag atatttcttc    900
 tctccagctc ttccacggca ggtctttggc tcagccgttt ggaaagcttc atctcgatct    960
 gctgccggat ctcctgtctt tcttcatcag tccttctggg gaaaatgttc cggtcttcta   1020
 gttcctgttt gcttggccgg ttccttagct tcacggccag gagctccttc ttgcatttcc   1080
 gtggcagtgt tccagaaata atggagtcgt tcagcgcctc ctcgtcctga tacaaaagca   1140
 agtcgtcttt gagttcagaa tttatgatca ggttctcctt gttctcctca gattccttag   1200
 cggcagttcg cttgttctcc aatgccccgt caaagctcca agcctcctcc ctctccttgc   1260
 cccgctccac gctggacgtt ctcgacagac ggacatccag ccgcttcttt ggagaccctt   1320
 tactttctct tccttgaaaa ctgtcctggc ggtgcttcgt ggccagcgcc ctgtgcagct   1380
 cctcaatgac gcggcttggg ggaagaggcc ggtggaccgt ggtgagatgc ggagaccccg   1440
 tgggtgtgga gagctggccc cggagggaag ggtcggcact cttcatgctg gaggcttgga   1500
 agagtgtggc ttggcctgtg acattttttg tggttttgga gcttgccttg ggtggcggag   1560
 tgggcagcag tggggggctg gggagctggc ccacggatct ctccagaggt ctgggaggac   1620
 tgtccaggga gtcagcccca gctaaggctt gggagagctc attggtggtg ggcaggaggc   1680
 tgccagcgtc tgcttcttca ccactggatg cagaaggcat cttggctgca tcgtccaagt   1740
 gggcagctga ggacagtggc ttgtccaggg agacctggtc cgtcccagtg gccaaggggc   1800
 ttccgggctg ggcatcttct gaagtcagcg tctccgccgt gggagtgggt ggganttccn   1860
 ccgcnctggc gagggtntac ctgtcat                                       1887



      <210> 2507
      <211> 2109
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(2109)
      <223> n = a,t,c or g


      <400> 2507
 ctcactctgt tgcccaggct ggattgcagt ggtgcgatct cggctcactg caacctctga     60
 ctcccgggtt caagcgattc tcctacctca gcctcctgag taactaggac tacaggcgtg    120
 agccaccaca ccctgctaat ttttgtactt tttagtagag atgggtgccg agaccagctc    180
 cgtgtgcgga gaccagctcg gttgtggaga ccctaaccca gcgttgctag aggaattaaa    240
 gacacacaca cagaaatata aagtgtggag tgggaaatca gggggctgac agccttcaga    300
 gctgagagcc tcaaacagag ttttacccac atatttattg acagcaagcc agtgataagc    360
 attgtttcta tagattatag attaactaaa atgggaaaca aagggatggg ccaaaacaaa    420
 ggtatgggcc ctggctagtt atctgcagca ggagcatgtc cttaaggcac agattactta    480
 tgctatggtt tgtggttcag gaaccccttt aagcggtttt ccgccctggg gataggccag    540
 ggtgttcctc gctctcattc cggtaaacca cagccttccc ancatgggcg ttatggccac    600
 catggaacat gtcacagcgc tgcagaggat tttgtttatg ggccagtttt gggggccagt    660
 ttatgtccag atttgggggg cctattcccc agcatatccc ccttcttgtt tttgcagggc    720
 aataaaagca aaggcagctt tatcacggtg agctacttct cgcaggagtc aggatctgca    780
 tctgcagact acacaaagac aaacaacaca gattaaaagc acaatcatca ttgaaatcac    840
 agagcttcca agtgttttca tccattttaa tgggttacta gctgctaatt tgtctgcagc    900
 tcctttaagg actccagttc ctggcattaa ggtcaggtgt gcctgggatg ctttaaatat    960
 ttgttctttt aattttgcca tatccaaaaa caagtttgta gagtgtcctt ctagatgctt   1020
 ttttattctt tcccaaattt tgatcttatt aacagacatt aatagtttcc acaaatcctt   1080
 atgtttagct tctacagtgg accatatcat ttgaggttga ggtgccacta taccgccacg   1140
 tttccagata atgggaactc ttgctgtatt tcttaccatt tctaccatct gactgttttg   1200
 ttcagaccag ctgaacatag tgtggctgtg gcacacagac tgacaggtgc aattcaagct   1260
 aaacatcccc ttaggggacc aatcaataat gattccatag gaattgttgc acagcacctc   1320
 tgcctgtttt gcaatgcaat cttcccaaac aaatacattc attatttcta gccaggtcca   1380
 attctgttta caaataggtt tttgagggca gtatacctca attacaggag cagatttatt   1440
 atggtaaata cggagaccag aaagcatgtg taactgtgtc atagagtgat tacatccagg   1500
 cattattgcc agccaagatt gataaatacg cccaataagt ataattgtcc tctgtgccag   1560
 cccttgttga aggaatactc atggcaatgg tgatcaccac tatcatagct atcattaaat   1620
 tactcattgt gactggttgt cccactttcc ttaggttttc ttctgccatc tgtgacagct   1680
 tcttgatctg tccccaggta ggtggctgcg ttcgatgggt gttgctcgtg acagttgggg   1740
 tccccctcag cgtcagtctc aacatggctg caaccagggg atcctcggga tcctcccaga   1800
 atctattcct cagcatcagg ctcatgataa ggtttcaggt gcctcgatga tatccaaatt   1860
 ggcagttgat ttggtccacg gggattgctt aagagtactc aggtgtcctc cagcttagtt   1920
 ccacgttctc caaccgtcgc tctggcgacc cttcaaccca ggttcgagcc ccatgtatgg   1980
 acaccacttg ctgagaccag ctcggttgtg gagaccctaa cccagtggca ctggagcaac   2040
 tcagcactac ctgcagcggc gcagctcctc gtgccgaatt cgtgcagccg gcgaagncgn   2100
 cgagtctcc                                                           2109



      <210> 2508
      <211> 687
      <212> DNA
      <213> Homo sapiens


      <400> 2508
 ccaggaacta cagctatagt agggggcgcc taggttggtg gctccagggc gccggatcgg     60
 ctcctttgag ggcccaccgc ggcccgagac tcctccccgg aagtttcctc ggatggcagc    120
 aggcacagcg aggtggccga gccgcccaga gaacgtccaa ggcccacctc cggctccgcg    180
 gatgccgtct cggcctccat ggccttggcc tcgacggcgc gggcgggggc agcctgggac    240
 tccacctcgc gcagcgccta gtagtggtcc tgggccggca gggccggggc ctgttccgcg    300
 cctgtgcctg cgccgttggt ctgcgagcac acgtgcctga cccgcgggag cgccctggag    360
 cccttgacgc ggcggctgtc cccgtcgcca tacaccttat agcggatcat gagcagaacg    420
 atgaagacga ggcccgaggc gacgatgacg cccccgatgg cgatgatcat ggtgccgccc    480
 aagaaatggg ccctcagcgg gcggcagggc gccggatccc cagcggtggt gaactgtaca    540
 cagcccacca ctcgcgttgc cggcagcgct gtggccccgt cgtcgtagac cgccagcacg    600
 cacaagtcgt aggcacggcc cgccgccagg tcattcacca gaaaggtctg actggtggac    660
 gggatcatcc tgtagacgag ggagtct                                        687



      <210> 2509
      <211> 876
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(876)
      <223> n = a,t,c or g


      <400> 2509
 gggaattgaa tttacaagat tttagtcatc ttgaccacag ggacctaata cctatcattg     60
 ctgctctgga atataatcag tggttcacaa aactgtcctc taaggatcta aaactgtcca    120
 ctgatgtctg tgaacagatc ttgagggtgg tgagtaggtc caatcgactg gaagaattgg    180
 tgttggaaaa tgctggactt agaacagatt ttgcacaaaa actggccagt gctctagcac    240
 ataatcccaa ctcaggactc cacacaatta accttgctgg caacccactg gaggatagag    300
 gtgtgtcctc tttaagtatt caatttgcca aactcccaaa gggattaaag cacttaattt    360
 tatctaaaac ccattatcan cctaaggngg tgaacagcct ttctcagtca ctcagtgcca    420
 atccattgac cgcctctacc cttgtccacc tcgacctctc agggaacgtc cttcgtggag    480
 atgacctctc acacatgtat aattttttgg cccagccaaa tgccattgtt catctggatt    540
 tatccaatac agaatgttcc ctggacatgg tctgtggagc tcttctccgt ggatgccttc    600
 aatatttagc tgtgctcaac ctctccagaa ctgtcttctc tcaccggaaa ggaaaagaag    660
 tacctccatc tttcaagcaa ttttttagta gttctctggc tttgatgcac atcaaccttt    720
 caggcacaaa actgtctcct gagcccttaa aagcactgtt attgggcctg gcttgtaatc    780
 ataacttgaa aggggtttct ctggatctca gcaactgtga gctgagatca ggaggtgctc    840
 aagtattaga aggttgcatt ggctgaaata cacaac                              876



      <210> 2510
      <211> 763
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(763)
      <223> n = a,t,c or g


      <400> 2510
 cccatatggg ccaccagatg ttacgggggg tggagggggt ctttgttctt agagctccca     60
 agatgcgacg ggccgctctc aagatggggg tgggctgctc ccaagatggc tgcaagcctt    120
 ttgttctctg acctggggtt cttggcctca aggattccaa agaatggaac cttgggccat    180
 gtggtcagtg ttatagctct agtagaagtc atgggtcacg gaagagaact gtggaaccca    240
 gtgactagtg ttcagctcga ttaggatgaa ccctgggccc ttagccatgc aggaacaatg    300
 gtcagcctct agcccgattg ggagcggcaa tggacacctc tctggatcag aagcacagcg    360
 gacaccctgc tggatccagt gggtggaagt caatggtggg tctgggacag cagtgaacag    420
 cagtggtgga cagtgagcga aagctcagct cgagctgtaa caaacacaga ccagaagagt    480
 gtgcagttgc aagatttaac agaatgaaaa cagctcccat acaatgggag gggatgcaaa    540
 gggggtttcc cacttcctgc tcaaatgcct gggtttatat cccaatcatt gtccctaccc    600
 ctgtactctc aggcgatatg tgatttgact atttctctac ttccttcctt tagcctagtt    660
 tgtaatttag tgagccctct ttgctacctg attggtcggg tgtgngctga gttacaagcc    720
 tcgtgtttaa gggtaggtgt gtcaccttcc ccngctagct tag                      763



      <210> 2511
      <211> 397
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(397)
      <223> n = a,t,c or g


      <400> 2511
 tttcgtaaan nnnnaaatat ctcaagtagt gctggctcgg agatgctacg cacgaaaagg     60
 tccagatatg cagttgggga catgacctct tgcacaggca ccttatggag agcaggagcc    120
 aagactggta ccaaaaattc attggatatg taaatgacaa gctgatttcg aatcaagggg    180
 tgagccacct gtatgactgc attgcaaaac tccagggagt tcatgaactg gacaagagaa    240
 ggaagtagaa gccagtcatc tttcagaagg cagtgccatt cctcgccttt ctcttctagc    300
 tttgtaggca gggaagagta gagaccactg agcccagttg caagtactgg acaaaagtag    360
 gtgttctcca cgatgtgatg ggccaccatg gtgttct                             397



      <210> 2512
      <211> 583
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(583)
      <223> n = a,t,c or g


      <400> 2512
 actgttctga gatctttgcc tccctcaggc tcccgagaat catggctcat tccaagcagc     60
 ctagtcactt ccagagtctg atgcttctgc agtggccttt gagctacctt gccatctttt    120
 ggatcttgca gccattgttc gtctacctgc tgtttacatc cttgtggccg ctaccagtgc    180
 tttactttgc ctggttgttc ctggactgga agaccccaga gcgaggtggc aggcgttcgg    240
 cctgggtaag gaactggtgt gtctggaccc acatcaggga ctatttcccc attacgatcc    300
 tgaagacaaa ggacctatca cctgagcaca actacctcat gggggttcac ccccatggcc    360
 tcctgacctt tggcgccttc tgcaacttct gcactgaggc cacaggcttc tcgaagacct    420
 tcccaggcat cactcctcac ttggccacgc tgtcctggtt cttcaagatc ccctttgtta    480
 gggagtacct catggccaaa ggtgcttctg accatactta ctggagcttc tggtccatgt    540
 ttctgcttgg aaatgcaccc ttttnaaatc atccctcttc ccc                      583



      <210> 2513
      <211> 777
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(777)
      <223> n = a,t,c or g


      <400> 2513
 cacgctcgcg gacggcgggg aggggcagtt cgacggcaca ttcgagcctg ccaccgtggc     60
 tcttccaggc ggcgagcacg ccgagaacgc cgtgcagatc cacaaggtgg tcacgggcac    120
 catggccctc atcttctcct tcctcatcgn ggncctggtg ctctacgtgt cctggaagtg    180
 tttcccagcc agcctcaggc agctcagaca gtgctttgtc acgcagcgca ggaagcaaaa    240
 gcagaaacag accatgcatc agatggctgc catgtctgcc caggaatact acgttgatta    300
 caaaccgaac cacattgagg gagccctggt gatcatcaac gagtatggct cgtgtacctg    360
 ccaccagcag cccgcgaggg aatgcgaggt gtgattgtcc cagtggctct caacccatgc    420
 gctaccaaat acgcctgggc agccgggacg ggccggcggg caccaggctg gggtctcctt    480
 ggcctgtgct ctgataatgc tccttgactg aaaactttaa ggggatctct tcccagagac    540
 ttgacatttt agctttattg tgtcttaaaa acaaaagcga attaaaaccc aacaaaaaaa    600
 ccccacccca caaccttcag gacagtctat cttaaatttc atatgagaac tccttcctcc    660
 ctttgaagat ctgtccatat tcaggaatct gagagtgtaa aaaaggtacc aatcattgat    720
 tttttttttt tttgtaaact aaaatgttta aaataaaata gcatttacag ttaaaaa       777



      <210> 2514
      <211> 412
      <212> DNA
      <213> Homo sapiens


      <400> 2514
 ggaattcctg agttccaacc agatcaccca actgcccaac accaccttcc ggcccatgcc     60
 caacctgcgc agcgtggacc tctcgtacaa caagctgcag gcgctcgcgc ccgacctctt    120
 ccacgggctg cggaagctca ccacgctgca tatgcgggcc aacgccatcc agtttgtgcc    180
 cgtgcgcatc ttccaggact gccgcagcct caagtttctc gacatcggat acaatcagct    240
 caagagtctg gcgcgcaact ctttcgccgg cttgtttaag ctcaccgagc tgcacctcga    300
 gcacaacgac ttggtcaagg tgaacttcgc ccacttcccg cgcctcatct ccctgcactc    360
 gctctgcctg cggaggaaca aggtggccat tgtggtcagc tcgctggact gg            412



      <210> 2515
      <211> 1392
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1392)
      <223> n = a,t,c or g


      <400> 2515
 gaacgttgta aagtgcagtc ctccacttta gtgtcttctc tggaggcgga gctctctgaa     60
 gttaaaatac agacccatat tgtgcaacag gaaaaccacc ttctcaaaga tgaactggag    120
 aaaatgaaac agctgcacag atgtcccgat ctctctgact tccagcaaaa aatctctagt    180
 gttctaagct acaacgaaaa actgctgaaa gaaaaggaag ctctgagtga ggaattaaat    240
 agctgtgtcg ataagttggc aaaatcaagt cttttagagc atagaattgc gacgatgaag    300
 caggaacaga aatcctggga acatcagagt gcgagcttaa agtcacagct ggtggcttct    360
 caggaaaagg ttcagaattt agaagacacc gtgcagaatg taaacctgca aatgtcccgg    420
 atgaaatctg acctacgagt gactcagcag gaaaaggagg ctttaaaaca agaagtgatg    480
 tctttacata agcaacttca gaatgctggt ggcaagagct gggccccaga gatagctact    540
 catccatcag ggctccataa ccagcagaaa aggctgtcct gggacaagtt ggatcatctg    600
 atgaaatnga ggaacagcag ctgctttggc aagagaatga gaggctccag accatggtac    660
 agaacaccaa agccgaactc acgcactccc gggagaaggt ccgtcagttg gaatccaatc    720
 ttcttcccaa gcaccaaaaa catctaaacc catcaggtac catgaatccc acagagcaag    780
 aaaaattgag cttaaagaga gagtgtgatc agtttcagaa agaacaatct cctgctaaca    840
 ggaaggtcag tcagatgaat tcccttgaac aagaattaga aacaattcat ttggaaaatg    900
 aaggcctgaa aaagaaacaa gtaaaactgg atgagcagct catggagatg cagcacctga    960
 ggtccactgc gacgcctagc ccgtcccctc atgcttggga tttgcagctg ctccagcagc   1020
 aagcctgtcc gatggtgccc agggagcagt ttctgcagct tcaacgccag ctgctgcagg   1080
 cagaaaggat aaaccagcac ctgcaggagg aacttgaaaa caggacctcc gaaaccaaca   1140
 caccacaggg aaaccaggaa caactggtaa ctgtcatgga ggaacgaatg atagaagttg   1200
 aacagaaact gaaactagtg aaaaggcttc ttcaagagaa agtgaatcag ctcaaagaac   1260
 aagtgagcct acctggtcat ctctgttcac ccacctcaca ttccagcttt aactccagtt   1320
 ttacatccct ttattgccat taactcgtta acttatgttg gctaataaag gcaaattcta   1380
 ttaaaaaaaa aa                                                       1392



      <210> 2516
      <211> 441
      <212> DNA
      <213> Homo sapiens


      <400> 2516
 atgttgacta ttggcggacg gggtctcaaa ggcgccactg agcgtgcgca gaaccgaccc     60
 ctgcagccct ttaggctgcg gtgccaaaga gtcggtcccg aagcggaagt gcttgttggg    120
 gccaggcttt gtaacggtct cctgagcagc gagcagaaaa tctgttatcg agagagacac    180
 agtgacctgc ccctaaaggt tcatgcgcat ccctcagacc cctctttaga cgcgccccgc    240
 ttctccctct gccctctccc cttgcccaag ccccgaggtg ggggcctggt gtgaatgctc    300
 cggccgaagt gaacctgcac ccccgcaccc gaaggcctct ttccggcttc tgggcaaggc    360
 ggccccggtg agctcggccg tcacacatct ctgctttttc ccaagaagag caggaaatgg    420
 ccaaacccca gaaaaaaaaa g                                              441



      <210> 2517
      <211> 387
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(387)
      <223> n = a,t,c or g


      <400> 2517
 cagattctta aaaatatttt tggtgaagga ttaccactgt aatttttcct aacttcgacc     60
 ggcactggtc ccagcgccca ggccatctcc cagcggtggc aacatgaagc caggcggcta    120
 gggcggaggt ggcggccctg atggcggcga gctggtggcc aacatgctcc cagtcgctgg    180
 cggcggtgcc tgctcctgac ctgggctcca ctcccacccc gtgcgccaag cgcagccaac    240
 gccgcccaca aaaggatttt tcaaatgttt ttttcgcggt gaaagaagtt tgaagactac    300
 tgcantaaac aacaacagag aaaaaggaag aggaaagagn ataaagattt ttgcttatat    360
 catgtgaatt attaaaaaga atgaagg                                        387



      <210> 2518
      <211> 586
      <212> DNA
      <213> Homo sapiens


      <400> 2518
 ccatggtgga gtgtccagcc tgccagcatt agagaccaac actgagtctt agagatacca     60
 gctaccacca ggttgagtgc atcagatccc ttttaccttg gaatgggcat caatttgttc    120
 ttaccagaat tgatatatgc tctaaatgag cttgtcttcc ccaactactt tgcctccagc    180
 agcaccacca tctgagagct tacagggtgc cttatccatt gacatacctg aaactaagga    240
 acccaccgat agccaaggag gtgtgacagt gaactcgaag ctacaaaatt catggtgcat    300
 actcatcatc cagaagcagc tagccagata gggttttgga atggcctgtt gaagactggg    360
 ctaaattgcg attaagatgt aatgccttgc aaagttggga gcagttcttc agaatatggt    420
 atatgcgctg aaatgcattg ggccaaaatg gatatatagt attgtgtctc cagtaggact    480
 atgtgcatac aggagtagcc tctattacta tcacacccag ccactcacct gtagaatttg    540
 tgcctcctcg ctccgaaatc tggagccagc tgggttatga tcctca                   586



      <210> 2519
      <211> 377
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(377)
      <223> n = a,t,c or g


      <400> 2519
 nggccccttt atgagaacct ttacgttcgt cctgaccaca cccttgtcac ccccaggccc     60
 gggtgctgcg cagcccccgg gatgcagtac aatgcctcca gcgccttgcc ggatgacatc    120
 ctcaactttg tcaagaccca ccctctgatg gacgaggcgg tgccctcgct gggccatgcg    180
 ccctggatcc tgcggaccct gatgaggtcg gtcctggaga ggcagggcat ggcgagggga    240
 gacaggatgg ggtagatgga gggtgagagg atccagatgc tcaacacaga tgagcccatg    300
 gcttccggcg ctgcccagag agctggagac acagagagac agagagggaa agatggagag    360
 acaccaggaa ttgtatt                                                   377



      <210> 2520
      <211> 718
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(718)
      <223> n = a,t,c or g


      <400> 2520
 aagaaggtgg gcaattacta cacaaccccg atctacaggt tccggatgaa atgccacctc     60
 tgtgtcaact acatcgagat gcagacggac cccgccaact gcgactacgt gatcgtgagt    120
 ggcgcccagc gcaaggagga gcgctgggac atggcggaca atgagcaggt gctgaccaca    180
 ggtgagcgcc acccacttac ctgcctgggg gccctggccc tgagtctgcg ctggggcccc    240
 caaagcccag ccgagctctg atcgttgcag agcatgagaa gaagcagaag ctggagacgg    300
 acgccatgtt ccggctggag catggcgagg ccgaccgcag cacactcaag aaggcgctgc    360
 ccacactgag ccacatccag gaggcccaga gcgcctggaa ggacgacttc gccctcaaca    420
 gcatgctgcg gagaaggttc cgggtgaggg gggctccagc ccggggtcag agaggatgca    480
 tggtggacca aggcccgggt ccagccctcc ccccaccaca tcctagcttt gagcaggcca    540
 cttgtacctt ctgagcctca gtttccccat ttgctacatg gtgccatgcc cctgtcttaa    600
 tccattctgg ctactataat accaaaatac catagacaga aacagtagaa aaaagaaagg    660
 gcacggtgac tcacgccttg tattgcggcc gctcggnngg tccncctaac gaaatgat      718



      <210> 2521
      <211> 850
      <212> DNA
      <213> Homo sapiens


      <400> 2521
 atggctgtgg tcatccctgc tgccttggga acagctgctc tggtgccctg gtccatcctg     60
 agggggaagg caccaaggta ctggctcctc ccattacttc tggacccaga taaagtgcca    120
 atcattagtg caagggatct gacttctcca gatgctgccc tggccagtct gacagctcag    180
 tctggagggt tagaggagtt acacctcaag ttagttcatg aagtagctgt gatggctaat    240
 actgaatgtc aacttgattg gattgaagga tgcaaagtat taatcctggc ttgcagattg    300
 tgggaccttg tgatcatgac acatccagcc ttttaccaga gtgtgcagtg gggaaaggga    360
 aatgatcaga catttcaggg acgactggac actggctgtg agctgatgtt gattccaggg    420
 gacccgaatt gtggtcctcc agttaaagta ggggtttatg gaggtatcat ttatcactgt    480
 gatcttacca aagaggagct ggagccaaga gttttccgag aggtgaccgt aaaaggaatt    540
 gatgcttctg attaccagac agtccagctc cccaagggta ctgagtcttc cagaaactga    600
 atcactggtt gattgatgat gacgaaaaat gtctctgttc ctttgcaatg agaggtcacc    660
 aatagggcac cagggtgttt atcaaggccc ctcccacctg ggagggctgg gaccacacag    720
 gccacagatt agggaatcag aacattgttt gtgaagggaa ggatgaggaa taaaggaggc    780
 gctgggatgt ttccccacaa tgttttctgt ggaaactagg gcattattat agcttggtga    840
 attacccttt                                                           850



      <210> 2522
      <211> 2142
      <212> DNA
      <213> Homo sapiens


      <400> 2522
 atgggtggag caggctcgcc gcaagtcata ctagtgagcc acacgccaca gtcagcgtct     60
 gctgcttgtg aagaaatagc ctaccaggta gctggcgtct ctgggaacct ggccccgggc    120
 aaccagccag agaaggaggg ccgggcgcac cagtgcctgg agtgtgaccg cgccttctca    180
 tcggcggcgg tgctcatgca ccacagcaag gaggtgcatg gccgggagcg catccacggc    240
 tgccccgtgt gcaggaaggc cttcaagcgc gccacgcacc tcaaggagca catgcagaca    300
 caccaggccg gcccctcttt gagctcccag aagccaagag tgtttaaatg tgacacttgt    360
 gagaaggcat ttgccaaacc aagccagctg gagcgccaca gccgcataca cacaggggag    420
 cggccgttcc attgcacgct ttgtgagaaa gccttcaacc agaagagtgc gctgcaggtg    480
 cacatgaaga agcacacggg ggagcggccc tacaagtgtg cctactgcgt catgggcttc    540
 acgcagaaga gcaacatgaa gctgcacatg aagcgggcgc acagctatgc tgtggccgtg    600
 gccatgggtg gtactgccca gtgcccgcca ggtgccactg cctgcctggg cactgccatc    660
 tgcccatcag ggttaagagc tcagcgtccc tccaacctta gtgtaccaga agcagctaag    720
 cctaaaagtg ggagaaacag aaaaattgaa gcccccacgt gggcactgtc tacctccaag    780
 gacccccaga ctgaggggct gcgaaatcct cagacctgtg ttcagatcag aagcaaccct    840
 ttctgtgcat ttgcccaagg tttcagtctc atctctgagc taaggaccct taactgtttc    900
 gtgggactct gtgactcgca atctggaaag cagcagcttg gtttctacag cggccaacca    960
 gcaacagaag cctggcagaa atactccttg gccgtgtgca ttctgagaag tgaacaggaa   1020
 attagtgcaa cacggttagg gttgaaaaac acaaatgtga acaagctgga tggtggttgt   1080
 ggagcctgga attttcttgg aggcatgtct gagcataact caccgccttc aggaagagca   1140
 atacttctgc ctgttgtgtt tactgaggtg ttcccaggtc cttggacacc ggagcaaggc   1200
 tcgcatatct gccgaatgaa cttagctccc acattccaag cctttctgcc caaaacaggg   1260
 tttcctattg accctcaaga attgttgcaa gggcccattg agagaacaat ttggccggga   1320
 acagtgtaca ctttccgttc agccatcgtc acagcacgtg ctgtgtgggt gcggccacgt   1380
 atggatcgca gagccgacct cagctcagcg acgcagagtg cttctgctga aaaatttgga   1440
 gggagggtta gtgctggcca ctgtgcactg ccgctgccag cacgcccggt cacagccagt   1500
 gtctatgggc gactggcgcg gctgcgaggc tgtctagagg actcctaccc ttctgctctg   1560
 agtgcgcaag tcttcctgga ctctccggct gtgggctgtg gtttggaaac gaggttgttc   1620
 atagaggctg ctctggggcc accatgcagg gcaacggtga cgtccagagg ccacctgctt   1680
 gacatctcca tcaccaaatc tccaggaaga ccctgtttcc tatctgtgtg cctccatggc   1740
 agtgaccagc aaaagcgcaa gggtgccgca gccacggcga aaagaaagtc caagggtgga   1800
 ggggtgaacg tggagggacg tctgtgcacc tggccccctg aagacccacc caaatcctgg   1860
 tctctggcct tcggccccct gcaagagaag accacggagc tcaacctcca cccgcggtgc   1920
 tgggcacgct gcttgagcca ctgggagctg ccaccagggc cccggggaag ggcccaggcc   1980
 ccggactgga ctggatctaa gtcgtttagg gaacagttgc ttaccttcac gctgtggggt   2040
 gttcaagaga agattagcaa acatcaagca aatcaaggta aggaggctcc tgcctacacg   2100
 ggtttggagg actcggaccc tggggggctg tgcgctgtgt ag                      2142



      <210> 2523
      <211> 10136
      <212> DNA
      <213> Homo sapiens


      <400> 2523
 atgcacaaaa gggagagctg tttatggtca ccagaactgc ccccatctat taataatgat     60
 gaaaataata atagccgaca attactgggc atttactaca cagccagtga cagcttccct    120
 ggcaatgaga gagggaatgg gagcagcagt agttggagaa gacatttcag tgaggacagc    180
 tattcttcac tgaaaagtct gccagcaaaa ttcatcccca agggaagcac aggtcttcct    240
 acactgagac agatgcccag cagcatggga caggcaccca gctggaatac agtcatcacg    300
 gagggagcca tcaaaggcca cttggacctt gagatcaaag ctgagtgttc aggatggcag    360
 aagggacagc agtctgagat tgaactgcaa ggtggcagcg aggctggggg cagggcaccc    420
 accaatgctg aggcttggcc tccgctgctg atacccaggc aaacagggtc tggagtggac    480
 ctccagcaaa ctccaacaga cctgccactg agggtcctga ctgttaaaag gaaaactaac    540
 aaacagaaag gacatccaca gcaaaacccc atctgtacgt cactatcatc aaagatgaaa    600
 gaaatacaaa ctaccatcag agaatactat aaacacctct atgcaaataa actagaaaat    660
 ctagaagaaa tggataaatt cctcgacata cacaccctcc caagactgaa ccaagaagaa    720
 gttgaatctc tgaatagacc aataacaggc tctgaaactg aggcaataat taatagctta    780
 ccaactaaca aaagtccagg accagatgga ttcacagctg aattctacga gaggtacaag    840
 gaggagctga taccattcct tctgaaacta ttccaatcaa tagcaaaaga gggaatcctc    900
 cctaactcat tttatgaggc cagcatcatc ctgataccaa agtctggcag agacacacac    960
 acaaaaaaga attttagacc aatatccatg atgaacgtcg atgcaaaaat cctcaataaa   1020
 atactggcaa accaaatcca gcagcacatc aaaaagttta tccaccatga tcaagtgggc   1080
 ttcatccctg ggatgcaagg ctggttcaat atacgcaaat caataaatgt aatccagcat   1140
 ataaacagaa ccaaagacaa aaaccacatg attatctcaa tagatgcagt aaaggccttt   1200
 gacaaaattc aacagccctt catgctaaaa attctcaata aatttggtat tgatgggacc   1260
 ccaaatctca ttaagctgat aagcaacttc agcaaagtct caggacacaa aatcaatgtg   1320
 caaaaatcac aagcattctt atacaccaat aacagacaaa cagagagcca aatcatgagt   1380
 gaactcccat tcacaattgc ttcaaagaga ataaaatacc taggaatcca acttacaagg   1440
 gatgtgaacg acctcttcaa ggaaaactac aaaccactac tcaacgaaat agaagaggac   1500
 acaaacaaat ggaagaacat tccatgctca tggataggaa gaatcaatat catgaaaatg   1560
 gccatactgc ccaagatcta ttgttgcaca ggatttctgg ctattacaag tcagttgcat   1620
 caagtaaatt ctgatttact tggctggtgg ctttgtgaac gacaattacc ctcaggcggg   1680
 ctcaatggaa ggccggagaa ggtggatcct tttcatacct tatttggaat tgctggattg   1740
 tcacttttgg gagaagaaca gattaaacct gttaatcctg tcttttgcat gcctgaagaa   1800
 gtgcttcaca gagtgaatgt tcagcctgag ctacatttta tatttcaaaa ttacccaaag   1860
 aaggagttgt cttcaaataa ggaaacacta acggggtccc cgctacaatt tcggactcca   1920
 ggagactcca cagagccgcc cttcggtcca ggtggtctct gcatccacct gtcctggcac   1980
 gtcaggagct gcgggcgacc ggagcagcag cagcagcagc cttccctgcc ccgcgccaaa   2040
 ctcccggcca gctcaaggca aggagtgatt gggtggagga gtctccttga ggctagaggc   2100
 cggcagttca tggaggctcg ggggcacgtg ggtggtggtt accacagtga agttgtgatt   2160
 tggttggggc gttcatactt tggaaacaaa agagcttatg cagaaaacac agttgcatca   2220
 aattttactt ttggtgcaag ctcatcttct gcacgagata ctaattatcc tcaaacactt   2280
 aaaactccat tgtctactgg aaatcctcag agatcaggtt ataagagctg gacaccacaa   2340
 gtgggatatt cagcttcatc ctcatctgcg atttctgcac actccccatc agttattgta   2400
 gctgttgtag aagggagagg acttgccaga ggtgaaatag gaatggcaag tattgattta   2460
 aaaaaccccc aaattatact atcccagttt gcagacaaca caacatatgc aaaggtcaca   2520
 ctgatgcaag aagtgaactc ccatagcctt gagcagctcc acccttgtgc ctttgcaggg   2580
 tacagccccc tgaaccctgc agctgctttt aaggctggtg ttgagtgtct gtggcttttc   2640
 caggaacaca actcctcacc agcaagggaa caaaactgga tgcagaatga gtttgacgac   2700
 ttgacagaag taggcttcag aaggtcggta ataacaaact tctccaagct aaaggagcag   2760
 gttctaaccc atcaaaagga agctaaaaac cttgaaaaaa aggtacaaag aggagctggg   2820
 accattcctt ctgaaactat tccaatcaat agaaaaagag ggagtcctct ctaactcatt   2880
 ttatgaaacc agcatcatcc tgataccaaa gcctggcaga gacacaacaa aaaaagagaa   2940
 ttttagacca atatccctga tgaaccaatt gatgcaaaaa tcctcaataa aatactggca   3000
 aaccgaatcc agcagcacat acaaaagctt atccactacg atcaagttgg cttcatccct   3060
 gcgatgcaag gctggttcaa catacacaaa atcaataaac ataatccatc acaaaaacag   3120
 aaccaacgac aaaaaccaca tgattatctg aatagatgca gaaaaggcct ttgacaaaat   3180
 tcaacaacac ttcatgctaa aaactctcaa taaattaggt attgatggga catatctgac   3240
 atatctcaaa ataataagag ctatttatga caaacccaca gccaatatca tactgaatgg   3300
 gcaaaaactg gaagcattcc cttttaagac tggcacaaga cagggatgtc ctctctcacc   3360
 actcctattc aacatagtgt tggaagctct ggccagggca atcaggcaag agaaagaaat   3420
 aaagggtatt caattaggaa aagaggatgt caaattgtcc ctgtttgcag atgacatgat   3480
 tgtatattta gaaaacccca tcgtctcagc ccaaaatctc cttaagctga taagcaactt   3540
 cagcgaagtc tcaggataca aaatcaatgt gcaaaaatca caagcattcc tatacaccaa   3600
 taacagacag acagagagcc aaatcatgag tgaactccca ttcacaattg cttcaaagag   3660
 aataaaatac ctaggaatac aacttacaag ggatgtgaag gacctcttca aggagaacta   3720
 caaaccactg ctcaatgaaa taaaagagga cacaaacaaa tggaagaaca ttccatgctc   3780
 atggatagga agaatcaata ttgtgaaaat ggccatactg cccaaggaat ggggcttcct   3840
 cagagctgaa atgtagtgat tgttttgctc ttatgagtct agccacccag cagagctcca   3900
 ggctggtgct gaagagtgtc tgcaaagagt cctgtaatgt tatctgtctt caggtcttgg   3960
 cagccatgga taccaccacc tgctccagtg gagcaatatt cgatgttctg cagcctctgc   4020
 tgctgatacc caggcaaacg gggtctggag tggacctcca gcaaactcca acagacctgc   4080
 agctgagggt cctgactgtt agaaggaaaa ctaacaaaca gaaaggacat ccacaccaaa   4140
 accccatctg tacgtcacca tcatcaaaga ccaaagaact agagaagcaa gagcaaacac   4200
 attcaaaagc tagcagaagg caagaaataa ctaagatcag agcaggactg aaggagttag   4260
 agacacgaaa aacccttcaa aaaatcaatg aatccaggag cttgtttttt gaaaagatca   4320
 acaaaattga tagaccacta gcaagactca taaagaacaa aagagagaag aatcaaatag   4380
 acgcaataaa aaatgataaa ggagatatca ccaccaatcc cacagagata catactaccg   4440
 tcagagaata ctataaacac ctctacgcaa ataaactaga aaatctagaa gaaatggata   4500
 aattcctgga cacatccacc ctcccaagac taaaccagga agaagttgaa tctctgaata   4560
 gaccaatcac aggctctgaa attcaggcaa taattaatag cctaccaacc aaaaaaagtc   4620
 cagtacctga cggattcaca gccaaattct accagaggta caaggcagag ctcgtaccat   4680
 tccttctgaa actcttccaa tcaatagaaa aagtgggaat tctccctaac tcattttacg   4740
 aggccagcat catcctaata ccaaagcctg gcagagacac aacaaaaaat gataatttta   4800
 gactaatatc cctgatgaac atcgatgcaa aaatcctcaa taaaatactg ggaaaccgaa   4860
 ttcagcagca catcaaaaaa cttatccacc atgatcaagt gggcttcatc cctgggatgc   4920
 aaggctggtt caacatatgc aaatcaataa acataatcca gcatataaac agaaccaatg   4980
 acaaaaatca catgattatc tcaatagatg cagaaaaggc ctttgacaaa attcaacaac   5040
 ccttcatgct aaaaactctc aataagttag gtattgatcg gacgtatctc aaaataataa   5100
 gagctatcta tgacagaccc acagccaata tcatactgaa tgggcaaaaa atggaagcat   5160
 tccctttgaa aactggcaca agacagggat gccctctctc accactccta ttgaacacag   5220
 cgttggaaat tctggccagg gcaatcaggc aggagaagga aataaagggt actcaattag   5280
 gaaaagagga agtcaaattg tccctgtttt cagatgacat gattgtatat ctagaaaacc   5340
 ccattgtctc aacccaaaat ctccttaagc tgataagcaa cttcagcaaa gtctcaggat   5400
 acaaaatcaa tgtgcaaaaa tcacaagcat tcttatacac caataacaga caaacagaga   5460
 gccaaatcat gagtgaactc ccattcacaa ttgcttcaaa gagaataaaa tacctaggaa   5520
 tccaacttac aagggatgtg aaggacctct tcaaggagaa ctgcaaacca ctgctcaacg   5580
 aaataaaaga ggttacaaac aaatggaaga acattccatg ctcatggata ggaagaatca   5640
 atatcatgaa aatggccata ctccccaaga ggactccatt attatcgctg cctagtacat   5700
 tatatgagga gctgtggaga cttaggtcct acttcccatt gtgccctcaa ctttacaaca   5760
 tggagcagaa taccacagac tgggtaattt ataaagaaca gtgcatttgg ctcacagctc   5820
 tggagactgg ggagtccaag agcactgcac cagcatttgg caagggttat cccatggcag   5880
 aatacatcat atggggcaga ttgacacctc acatggctgg ctactcctct gagacaaaac   5940
 ttccagagga acgatcaggc agcaacatct gctgttcacc aatatccgct gttctgcagc   6000
 ctctgctgct gatacccagg caaacagggt ctggagtgga cctccagcaa actccaacag   6060
 acctgcagct gagggtcctg actgttagaa ggaaaactaa caaacagaaa ggacatccac   6120
 accaaaaccc catctgtacg tcaccatcat caaagaccaa aggatcaaat tcacacataa   6180
 caatattaac cttaaatgta aatgggctaa atgctccaat taaaagacac agactggcaa   6240
 attggataaa gagtcaagac ccatcagtgt gctgtattca ggagacccat ctcacgtgca   6300
 gagacacaca caggatcaaa ataaagggat ggagggagat ctaccaagca aatggaaaac   6360
 aaaaaaaggc aggggttgca atcctagtct ctgataaaac ggactttaaa ccaacaaaga   6420
 tcaaaagaga caaagaaggc cattacatga tggtaaaggg atcaattcaa caagaagagc   6480
 taactaccct aaatatatat gcacccaata caggagcacc cagattcata aagcaagtcc   6540
 ttagagacct acaaagagac ttagactccc acacattaat aatgggagac tttaacaccc   6600
 cactgtcaac attagacaga tcaacgagac agaaagttaa caaggatatc caggatttga   6660
 actcagctct gcaccaagtg gacctaatag acatctacag aactctccac cccaaatcaa   6720
 cagaatatac attcttctca gcactacacc acatttattc caaaattgac cacatagttg   6780
 gaagtaaagc actcctcagc aaatataaaa caacagaaat tataacaaac tgtctctcag   6840
 accacagtgc aatcaaactc gaactcagga ttaagaaact cactcaaaac cgctcaacta   6900
 catggaaact gaacaacctg ctcctgaatg actactgggt acataacaaa atgaaggcag   6960
 aaataaatac attatttgaa accaacgaga acaaagacac aacataccag aatctctggg   7020
 acacattcaa agcagtgtgt agagggaaat tcatagcact aaatgcccac aagagaaagc   7080
 aggaaagatc taaaattgac accctaacat cacaattaaa agaactagag aagcaagaac   7140
 aaacacattc aaaagctagc agaaggcaag aaataactaa gatcagagca aaactgaagg   7200
 aaatagagac acaaaaaatc cttcaaaaaa tcaatgaatc caggagctgg ttttttgaaa   7260
 agatcaacaa aattgataga ccactagcaa gaccaataaa gaagaaaaga gagaagaatc   7320
 aaatagatgc aataaaaaat gataaagggg atatcaccac tgatcccaca gaaatacaaa   7380
 ctaccatcag agaatactat aaacacctct atgcaaataa actagaaaat ctagaagaaa   7440
 tggataaatt cctcaacaca tacaccctcc caagactaaa ccaggaagaa gttgaatctc   7500
 tgaataaacc aataacaggc tctgaaattg aggcaataat taatagctta ccaatcaaaa   7560
 aaagtccagg accagatgga ttcatagcca aattccacca gaggtacaag gaggagctgg   7620
 aggccagcat catcctgata ccaaagcctg gcagagacac aaccaaaaaa gagaatttta   7680
 gaccaatacc cctgatgaat attgatgcaa aaatcctcaa taaaatactg gcaaaccgaa   7740
 tccagcagca catcaagaag cttatccacc atgatcaagt gggcttcatc cctgggatgc   7800
 aaggctcgtt caacatatgc aaatcaataa acgtaatcca ggatataaac agaacgaatg   7860
 acaaaaacca tatgattatc tcaatagatg cagaaaaggc ctttgacaaa attcaacaac   7920
 ccttcattct aaaaactctc aataaattag gtattgatgg gacgtatctc aaaataataa   7980
 gagctatcta tgacaaaccc acagccaata tcatactgaa tgggcaaaaa ctggaagcat   8040
 tccctttgaa aactggcaca agacaggggt gccctctctc accactccta ttcaacatag   8100
 tgttggaagt tctggccagg gcaatcaggc aggagaagga aataaagggc attcaattag   8160
 gacaagagga agtcaaattg tccctgtttg cagatgacat gattgtatat cgagaaaacc   8220
 ccatcgtctc aacccaaaat ctccataagc tgataagcaa cttcagcaaa gtctcaggat   8280
 acaaaatcaa tgtgcaaaaa tcacaagcat ttttatacac caataacaga caaacagaga   8340
 gccaaatcat gagtgaactc ccattcacaa ttgcttcaaa gagaataaaa tacctaggaa   8400
 tccaacttac aagggatgtg aaggatctct tcaaggagaa ctacaaacca ctgctcaagg   8460
 aaataaaaga ggatacaaac aaatggaaga acattccatg ctcatgggta ggaagaatca   8520
 atatcgtgaa aatggccata ctgcccaagg taatttatag atttaatgcc atccccatca   8580
 agctaccaat gactttcttc acagaattgg aaaaaactac tttaaagttc atatggaacc   8640
 aaaaaagagc ccgcattgcc aagtcaatcc taagccaaag gaacaaagct ggaggcatca   8700
 cactacctga cttcaaacta tactacaagg ctacagtaac caaaacagca tggtactggt   8760
 accaaaacag agatatagac caatggaaca gaacggagcc ctcagaaata atgccacata   8820
 tctacaacca tctgatcttt gacaaacctg acaaaaacaa gaaatgggga aatgattccc   8880
 tatttaataa atggtgctgg gaaaactggc tagccatatg taggagaaag ctgaaactgg   8940
 atcccttcct tacaccttat acaaaaatta attcaagatg gattaaagac ttaaatgtta   9000
 gacctaaaac cataaaaacc ctagaagaaa acctaggcaa taccattcag gacataggca   9060
 tgggcaagga cttcatgtct acaacaccaa aagcaatggc aacaaaagcc aaaattgaca   9120
 aatgggatct aattaaacta aagagcttct gcacagcaaa agaaactacc atcacagtga   9180
 acaggcaacc tacagaatgg gagaaaattt ttacaatcta cccatctgac aaagggctaa   9240
 tatccagaat ctacaaagaa ctcaaacaaa tttacaagaa aagaacaaac aaccccatca   9300
 acaagtgggt gaaggatatg aacagacact tctcaaaaga agacatttat acagccaaaa   9360
 ggcacatgaa aaaatgctca tcatcactgg ccatcagaga aatgcaaatc aaaaccacat   9420
 tgagatacca tctcatacca gttagaatgg cgatcattaa aaagtcagga aacaacagac   9480
 caagctccaa tgtcttctct gtgaaacttt ctgagatcca atccttggct ctcatagaga   9540
 ctaggtgctt aatgaatgct gatgaacagg gtgtgccact gattcaagaa atgctggaat   9600
 cttgggcaag tatttgcaaa gttcccaagt atccaaatgc cgaagcagtg cggccagaag   9660
 agcaaacacc ccacctgcac ccaggtgaaa taaacagcca tgttgctcac acaaagcttg   9720
 tttggtggtc tcttcacacg gacacgcatg aaatttggtg ccgtgactcg gatcggggga   9780
 cctcccttgg gagatcaatc ccctgtcctc ctgctctttg ctccgtgaga aagatccacc   9840
 tacgacctca ggtcctcaga ccgaccagcc caagaaacat ctcaccaatt tcaaatccgc   9900
 acacaagaac ttccaaacgc ctgaaccgca gcggccaggc gttcctccag aacctccttc   9960
 cccaggagct tgctacaagt gccagaaatc tgaccaccag gccaaggaat gcctgcagcc  10020
 caggattcct cctaagccgt gtcccatctg tgcgggaccc cactggaaat tggactgttc  10080
 agctcacctg gcagccactc tcagagcccc tggaactctg gcccaaggct ctctga      10136



      <210> 2524
      <211> 353
      <212> DNA
      <213> Homo sapiens


      <400> 2524
 cgaggttgac cacaggggcg attacgtgtc ccatgaaatc atgcaccatc agcggcggag     60
 aagagcagtg cccgtgtccg aggttgagcc tcttcacctt cggctgaaag gctccaggca    120
 cgacttccac gtggatctga ggacttccag cagcctagtg gctcctggct ttattgtgca    180
 gacgttggga aagacaggca ctaagtctgt gcagacttta ccgccagagg acttctgttt    240
 ctatcaaggc tctttgcgat cacacagaaa ctcctcagtg gccctttcaa cctgccaagg    300
 cttgtcaggc atgatacgaa cagaagaggc agattacttc ctaaggccac ttc           353



      <210> 2525
      <211> 412
      <212> DNA
      <213> Homo sapiens


      <400> 2525
 ccagtacaca cttctttaat cccgtagtaa attttctctt tatagccaat tcccaaagtc     60
 aagtatattg actcataaaa ataccttctg ggaagcatgt gactgatttc cagctgagag    120
 gccctgccac tggatggtta agttcatagg ccccagagtc agaagggggt tggaatctcc    180
 cctctgccat gcctgctact tggccttgtg tacgctcgcg ctcgtgcgct tgtgcgctct    240
 ctctcgctct cgctctctct ctctcatgct gattctgcag gcattctaca ggcctcccat    300
 gtcccaggag ccagctctgt ccacagtgct cttcctgctc ctgctcctgg ccaaccctcc    360
 aaccaaggtg tctaggagcc acaggaaaga gcgggttctc ttgctagttg ct            412



      <210> 2526
      <211> 808
      <212> DNA
      <213> Homo sapiens


      <400> 2526
 atggccttcc tagaaacttc tgcacccctg tatgaacaca tatggacact tcaggttgct     60
 ttctccactg ttggtctggg agagaccctg aaagttgcca tgatcagcat gtccacatca    120
 tctgggtatt ttcttcagct attacaatac tgctgctcct caaccatcac catcactgga    180
 tacaagggct tcctaagaga cctgaaggtg gagacaaggg ccgatggtgt aatgaggaca    240
 atggctcccg aaaagctgct aaagagtatg ccaatactac agggacaaat tgatgcactg    300
 cttgaatttg atgtgcatcc aaatgaacta acaaatggtg tcataaatgc agcatttatg    360
 cttcttttca aagatcttat caaacttttt gcttgctaca atgatggtgt tattaactta    420
 ctcgggacat ggatgaagct ggaaaccatc attctcagca aactattgca acgacagaaa    480
 accaaacact gcatgttctc actcataggt gggaatcgaa caatgagaac acttggacac    540
 aggaagggga acatcacaca ctgggccctg ttggcgggtg ggggtgctgc ggaaggatag    600
 cattaggaga aatacctaat gtaggcctag ataatatatt acttagcctt gagaaactga    660
 gaaatccccc actgtgtcac cttctagagc ccctgtcaac cctttgcaac tccaagagac    720
 aagtcactcc tactttccag aaaacattca gaagcaagca ccagcccttc cccagaggtc    780
 aagcagcaga aagggccttc cactgcag                                       808



      <210> 2527
      <211> 989
      <212> DNA
      <213> Homo sapiens


      <400> 2527
 gcggccgcct gtcggcttgc tggagactcg gttgaggtga ccacagaggc cacactagtg     60
 ggggtggagt tggcctgagc ggaggtggct gttgtcccct tcagtgatgc tggggtgggc    120
 tgtgggatgt tgacgagcag gctggtgttg ggaacattgg cgacgcggat gaggccctgc    180
 tggatgatcc tttgtccctg aatctgcaca ctgggcaccg acgcccgggg ggccaggagg    240
 aggggcggtg gccctgtgct ggaatgttgc ctaatgctgt ggatttgctg agccccccct    300
 gacgagtggg ggcatgacga cctgtgagct cgcctgtggc cccagctttg aggacgcctg    360
 ctgcccacct cggaccaggg gcgggggtat gacactgccg ggcatccgag ctgaagaggt    420
 ctggagtgat ggcttgccag caggaatgtt ctgagtgccc cgaacaagcg ggggaggggt    480
 ggtcacggtg ctcccaacag aacctgtggg cttctgggcg gtggcttcct tttgtatttg    540
 actctgccgc aactttttca acaacacgag ttttgcttct tctaacctca attcttcctt    600
 cagctgcttg atcatccttt ctcgttcttc aggactgctt ttcatgaggg cctcggtgct    660
 agtctccttc aaggccaccg tggtcagccc attcactctc gggctcgagg gctgctcgtt    720
 gtcggagagc acaatcacgt caggtgaggg gggtctcctc tcggacttca tgtcatctat    780
 ccgtgatcct cagagacatc ttgcaaaaat tatgtgatgc acaccttttt tccagctggc    840
 cccattttgg cacagaacaa aacaaagccg tccacactcc cacgttctgg acaactgggt    900
 ggctggatgt ctgtgtgagg tgcgcatgtc cacgggccca tcgcccacca gcccttcgcc    960
 tctgcccatg gccatggccg tggcctctg                                      989



      <210> 2528
      <211> 1429
      <212> DNA
      <213> Homo sapiens


      <400> 2528
 tttactggcc cgaggcgctg gaagaacaaa tccagcccct ccacttatgt cctgtggccc     60
 ttggggcaag tttcttaagt gttgtgaggt ctataaaagt ggaccataca aggtgcagta    120
 ggaagagatc accatccaca gtcgggctga ggctgaaagc acgtaccaga tcaagtatga    180
 ggagctgcag acgctggctg ggaagcatgg ggatgacctg cgttgtgcaa agacagatct    240
 ccgagatgaa ccagaacatc agcaggctcc aggctgagac tgagggcctc aaaggccagg    300
 gggcttccct ggaggccgcc atcgcagatg ccgagcagtg gggggagctg gccattaaag    360
 atgccaacac caagctgtct gagctggagg ccgccatgca gcgggccaag caggacatgg    420
 cacgcagctg ggtgagtacc agaagctggc cctggacatc gagatcgcca cctacaggaa    480
 gctgctggag ggcgaggaga gccgtctgga gtctgggatg cagaacgtga gtatccataa    540
 gaagaccacc agtggctatg caggcgctcc agcgaggata gtctcccttc tccagaatga    600
 actgctgtcc ctggaagtcg gggtactcaa aggccaccca actggaaaag gagaagagct    660
 gggagctcca tactcagagt gctcctttgg actgtgccga aggacagtga tgctcaccca    720
 ggctccaagc tccgtcgtga ggtccaggaa cagcaggaac cacaccgtga actctggtgg    780
 atcctgcctg agtgccagca cagtggccat ccctgccatc aacgacagca gtgcagccat    840
 gagtgcctgc agcaccatca gcgcccagaa gagaacatgc tgcacagcct gtgaacctgc    900
 gaggaagtac aaggacactg cctcccatca agaaccagca gtctgtcagc cggcctgcca    960
 gctggaaact gcagacccca aaggaggagg tgtcctggcc ctgccccagc caccctcgcc   1020
 aggcatgctc tgctggcctt actgccgagc ccatgccacc gactactttc tggctaactt   1080
 cttctcagag tttccctgcc actttttgca ccgagcaggg gctgcccaga cgcaagccac   1140
 tggtgacggg atggagcatg ggcagagcag ggagctgcca aagaggaagg cccccaggga   1200
 agagtcagag acttctgagg aaaaatcccc taacaagtgg ggccctgttt ccaagcagaa   1260
 gaagcagctc ctggttgaca ttctcaccac aataatcagg cctacaagag gtaatgctta   1320
 cacaggcctg agcactagaa aatggaagcc aagatccgag gaaaatgctc tgatgcagcc   1380
 caacaagaag gacgagaagg ggactcttac acagaaactg gggttatag               1429



      <210> 2529
      <211> 4235
      <212> DNA
      <213> Homo sapiens


      <400> 2529
 tttgaacact gcaaaaggct tttattttat aggcaccact gcaaaatgag gaatcacatc     60
 aaaacatatc aaatagaaaa taataattta ttttaacttc attttactgt ttgtaactaa    120
 tcatgatttt gtgaacttgc ctgtataagt ctgtaccttc aaatctacaa agcaaaagtt    180
 tactacaatg agcacttaaa attccacaaa ccgtctccat ccacaacttt cctgtacatg    240
 caaattcttt cagtgggctg caatatttgc aaacatgctt taaacttcca taaagatgca    300
 agatattttg ctttctgcta aaacctttac actctcttgg gaaccttaac caggaaaatg    360
 tttaaatgta tatcccaact ctaaacgctg ccggtttggt tatatgtatt aaatcgttaa    420
 ccaccgggtt gggtggtttt gagttgaaac cttcacctaa atgataatat cttaacggtc    480
 acgcatatga aacacattca gtaacgtacc attataaaat agggttccat taaaaataca    540
 tactggcagt tgtatttgtg ttttaggcag gaaaaaaagc gtgtttaact tttttatatg    600
 aatatagttt aaacaagtta ttctgtgaaa gtatgcttaa taaaagatct ttctgaaatt    660
 taaacacttt atgtaaaagg gtacaggtag aaaagtacaa ttgctatttg aaaaaagctc    720
 tgtttgttaa tattgccttc caagatagta agggtgtttt tctctctctt cccttaaaat    780
 agacctatga cacccagagt tgtagggttt gcaaatttgg actataaaca tgaagaccgt    840
 acttatctta tatacaaaaa cttgccgcat tgaacgaggc aggaatttct accccagtgg    900
 tagtggtctc ctttatgtac ataatgcaga agtgaaaatt atacagtagt caccgatagg    960
 aaggaattgt atactctagt gccgtccggg gattttgtgc cgtgggttaa gagttcttgg   1020
 atcgtcatcc agttatcgaa gattttctta ttcctcttct tcatcatctt tttgtggctc   1080
 agttcgagaa tgttcatctc cttcctgtca tcggctgctt gctgctcctt gagacaatcc   1140
 aacctgctct gcatcatgaa ctcgcgccgc cgccgctgct ccttggcctt caccaggtgc   1200
 tgcttcctct cctccttgct ccagtagcgc cccatcttca tctcgctcac cgcgtcgtcg   1260
 tcggtggtca tgccgctgcg ctcttcccgg atcttcaggg cgcgctcccg cagcaggcgg   1320
 tcccgcacgg gcctcttggt gatgtagcgc gtcccgtcgc tgcggatctt caccttccac   1380
 tccatgcgcg gctccgacgg ggtgggagag ctcaggtcct tgcacatgct caccaggctc   1440
 atctggcttt gcgcgtactc cacggccgac ttctgctgga tcagctgcat gtagctctgg   1500
 tagtgctggg cgtgcgccgg gatgtgcgcg tgcttgtatg gggagtggtg ataggagggc   1560
 aggtaggcgc tgcccagctt ctggctgggc gtggggctcc ggctcccgtc gctggctctc   1620
 cgctctttgc tttccagggg ctggttgggg tccagctcct tcagggacgg gctataggta   1680
 ggggtgccca cttcgggatc ttccgtgatg gagagcagat tcttggaggc tggcccgtag   1740
 gcttccgtgg tccccacagc cccttcgctg ctcgggcagc tgatgccctc cgccgctctc   1800
 ctcaaggagt tgtcggggga gatctccagg gtgagcgggg tgctgcggca gctctcgcct   1860
 gtgttgtagg cgctcgagct gtccttgtcg gatttctccg ggagctcggt gatatctgag   1920
 agctcgtgtc tgcgcacgtc gatgctggtg ttgtagttgc ggaagccgct gttgtgcagc   1980
 atccaggact cgcggtactg ctccttgagc tgctgcatct tgtgggcgcg cacgatgctc   2040
 aggcactcca gctcgatgct gcgcagctct tcgttcagca gctccagctc cttgtccacg   2100
 ctctcagggt cactcttgcc ggcgtccagg gggccgctag ggtagtacag gccgtaaggg   2160
 gtggcgctct tcacctggca cttgagctcc aggagctcgc ggaagcgctc gcactcgtcc   2220
 accgggatcc ccaggtaggc ggcgcccgtg cactcgggcg aaatgaacga cttgttgctg   2280
 aagggcaggt cgccgctgcc caaggtgtcc tggctgcagg tgagcttcct ctgccccgcc   2340
 agcgggttgg aggatgcggt ggcgtcgtcg ccattgttct cttgctccga gctctcgtca   2400
 ttacgggtgc tctcgtcggt ccgccccaca ccgctgtcct tctcgtgctg gttggacaag   2460
 atggtggctg tatctgtggt cccaccgtct tcgtcgtgct tcttctgctg cagcacgcta   2520
 gctgtgaatt gcatggcctg gtggtgctgc tcctccagca tgtccatgtg caggtcatcc   2580
 agaaagtcgt tcctgtcatc atccatccag ccctcatcca gctggagttc agcccttgca   2640
 atcagcaatg aaaagttttt attttcttca ctggttagaa gagccacagc ctcttcacgg   2700
 ttctgcacct ctatcccatt aatctggata atgcggtctc cttctcggat gcgcccatcc   2760
 ttggctgcaa tgctgttagg gtcaatctca ctgatataaa tcccaatgtc gtcttcatcg   2820
 tccgtccggt agcacacagt gaggcccagc ttgtcctggc tgttcattct gtagaggtcc   2880
 acttcctcca gctccagctc ctccctgtcc atctcctgat ggatgtctcc aatgtagtca   2940
 tttggatcgt agtattcatg ggctgaggga tgctcctctg gcaagagata gggatccagc   3000
 acgggtgggc tgggagagga catcttagtg agggccatga tatgttcaaa ggtgatgtcg   3060
 gtttgggttc ccgtgtccac cagctgagac tctgatggag gcgtgaacat tttggtcctt   3120
 ggtgttcttc tcaacacctg caccactatg ggctccttgg ctgtcttgaa agcttccaca   3180
 gcctggtcat gagttgctct ggataagtct ctgccgttga cctcaataat cctgtcatga   3240
 atttgcaggc ctccttcctt ggctgcaggc ccactgtcaa ctatcttgga tacaaagatt   3300
 ccttcactgg atgatccatc gtggttatcc acactcggcc ggccaccaat aatattgaat   3360
 cccagggagc cggagtcccg atgcaggaca agagtcagac ttttggtttc ttcgcccttg   3420
 ccgccgggcg gcgcggccac gcagcggctg agcgagtcga ggcgcgcgct gtattcggtg   3480
 aatttcttct ggtagcgcag cgcggtcatc tgcagctcaa gctgcgccgc ggccagctgg   3540
 gccaccagcg acttctcgcg cttcccagcg cgcagcgcct ccttcttgag cgccttgtgc   3600
 agcgcgccca ggcgggcctg gagcgcgccg ttgtgcgccc gcagcgctcg cgcgcagcag   3660
 tggccgcccg cgcgctgctc gccgtgcgtc aagggtagcc cgcagccctc ctggcagcgg   3720
 cccactggcc gcgcgtcgca cgcgtcgcgc atgtgcgcct ccacgtcgcg ccgcagcagc   3780
 acctggccgc aacccgcgtg gcgacagcgc gcgggcgcga agtcgcagcg ctcgaggtgc   3840
 tccggcagct gctgcagctt gaccacccgg ccgcagccgc gcgtcgcgta cgcgcacttg   3900
 atgtccagct tgaggataag gcgcttgagc ggcaggacgt ggttgagctc tttggccgac   3960
 aggcgaccgc ggcagcgcgc cgggcagctg ccctcctgca ccacccaggg cagcacgcag   4020
 ccggcgcaga agacgtggcc gcacggcgtg gtcagcgggt cctccaggac cttgtggcac   4080
 agcgcgcact tcaggtccgg gtccacgtcg ccgtcgaagc ggtccagctc gaagcccatg   4140
 gtggcggcca ggccccgggg tcgccgccgg gcggccgggc gccccctccc tccccacgag   4200
 gcggcccaga caggccggct acgccgcccg cgcgc                              4235



      <210> 2530
      <211> 792
      <212> DNA
      <213> Homo sapiens


      <400> 2530
 attgagacca tagagagccc ggcggaattc atttttttct tcaagctaga aatattacgg     60
 cttatgaagc atgtgagaca gtccccgcca tgtgctgatt acacagaccc ctgtaccaga    120
 aatcagaagg aaaggagtca gacttgaatc aaagaaatgt ctctggcaca caggccttca    180
 aattgatggc tggagcctgt cttttaagaa caaattaatt cattatagga aaaaccctaa    240
 ctaattgaaa ggtctaaatt cttcaggttc tcttgtgatc ctgggaaatg ctagaccgtg    300
 agcatcttga tggaggatgt gaactgccac ttcctcacag gcagcaggca ggtgctgaat    360
 aagtgcttgc tgaatgaatg aatgaatcac gccaaggggc atgttacctg ttccgccaaa    420
 atctgctgct gctgctgctg ctgctgcctt tgctcccgca ggaactgttg cttctgctgc    480
 tctatcaact gggcccgctg atcaatgagc atctgcttca tgatggctgc ttggggctgg    540
 ctgcccagga agccggggcc tgcgggactg gctcctgaga ccatgccacc tgagcctggg    600
 ggcacggagg actgcatggg gcctgtggtt cggggaagtc caactggatg ctgctcctga    660
 ccgtgggatg gaagtgcagc gtaagccatg ggctgattca tcactccttt ctgcttcatg    720
 agaagcaggc gtttctggtc ttcgctcagg tgtgccctgg gggcctgaag ctagaagagg    780
 cggacgcgtg gg                                                        792



      <210> 2531
      <211> 431
      <212> DNA
      <213> Homo sapiens


      <400> 2531
 agtttacgcg ttccgacgag ctggcccgcc actacaggac gcacacgggc gagaagcgct     60
 tctcctgccc cctctgcccc aagcagttct cccggagcga ccacctgacc aagcatgctc    120
 gccgccaccc aacctatcat ccagatatga tcgagtaccg gggacgtcgt cgaactcccc    180
 gcatcgaccc gccactcacc agcgaggtgg aaagctccgc ctccggctcc ggtcccggcc    240
 cggcgcccag cttcaccacc tgcctgtagg acagtcattg ctgtcagtct taccctcaag    300
 gatgatcccc caggccgttg tccctgcttt ctctctgcac atccttcttt cccagagtca    360
 ttacaccaag gcacagactg gttcctctgc tctgagggtg gtccaggcag acatgtggac    420
 tctggggagg g                                                         431



      <210> 2532
      <211> 588
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(588)
      <223> n = a,t,c or g


      <400> 2532
 ccggtccgga attcccgggc tcggccaagc tcgtgttcct cgacctcagc tacaacaact     60
 tgacccagct gggcgccggc gccttccgct cggccgggag gctggtgaag cttagcctgg    120
 ctaacaacaa cctggtgggc gtgcacgagg acgccttcga gaccctggag tcgctgcagg    180
 tgctggagct caacgacaac aacctgcgca gcctcagcgt ggccgccctg gccgcgctgc    240
 ccgcgctgcg ctccctgcgt ctggacggga acccctggct gtgcgactgt gacttcgccc    300
 acctcttctc ctggatccag gagaacgcat ccaaactgcc caaaggcctt gatgaaatcc    360
 agtgctccct gcccatggag agcaggagga tatccctgcg tgcgtgtcgg aggccagctt    420
 cacgagtgta ggttcacctg tcatcacaga cctctgcatc atcattttct ctggtgtggc    480
 cgtgtcattg cggcatcatc tcagcttctc ctgccactgt ggtcagtgct ccagaggtgn    540
 cacccaacaa agatgcggag gatgaagacg aggacgagga tgactgag                 588



      <210> 2533
      <211> 498
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(498)
      <223> n = a,t,c or g


      <400> 2533
 attcccgtgt cgacgatttc gtagcgcctg agagggcggt ggggtggcgg ngttcctgcg     60
 cgcggcccgc catggatgtg gaggaggcgt tccaggcggt gggggagatg ggcatctacc    120
 agatgtactt gtgcttcctg ctggccgtgc tgctgcagct ctacgtggcc acggaggcca    180
 tcctcattgc actggttggg gccacgccat cctaccactg ggacctggca gagctcctgc    240
 caaatcagag ccacggtaac cagtcagctg gtgaagacca ggcctttggg gactggctcc    300
 tgacagccaa cggcagtgag atccataagc acgtgcattt cagcagcagc ttcacctcta    360
 tcgcctcgga gtggttttta attgccaaca gatcctacaa agtcagtgca gcaagctctt    420
 ttttcttcag tggtgtattt gttggagtta tctcttttgg tcagctttca gatcgcttcg    480
 gaaggaaaaa agtctatc                                                  498



      <210> 2534
      <211> 758
      <212> DNA
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(758)
      <223> n = a,t,c or g


      <400> 2534
 accacctcaa ataaattaga agttcgaaat tcatcaaaca aaactaattc tttatttggg     60
 caatatgata acattaatac acagataact ttgaattcta gcaactgtaa aatctaaact    120
 taaatgttat ttaccgtata tttagtgaat ttatttttcc ctaccttcac gggacattaa    180
 aataggaaag gaagttaggt tcaaaggaga aatggggctt tgtagtcatc gctgccacct    240
 gaagccacct gcctctagcc atggtcaacg ccactgtgtt cttttgacat cattgttgat    300
 ggtaactcct ttggcccatg cagctccttc gagctgtttg ccgacaaagc tccaaaaaca    360
 gtggaaaact ttcgtgcact gagcactgga agaaaagggg ttgggtataa gggttcctgc    420
 tttcacagaa ttattccagg gtttatttta tctgccagag tgctgacttc acacaccata    480
 ataatgccag tccatctacc aggagaaatt tgatgatgag aacttcatcc tgaagcacac    540
 aggtcctggc atcttgtcca tggcaaatgc tggcccgaca caaatggttc ccagtttttc    600
 acctgtgtgg ccaagactga gtggctggat ggcaagcaca aggtctttgg caaagtgaga    660
 agagggagtg aatatcatgg aagccatgga gtgctctggg tccgggaatg gtgagactgg    720
 caagaagata cccactgcca nctgcggaca actctaat                            758



      <210> 2535
      <211> 72
      <212> PRT
      <213> Homo sapiens


      <400> 2535
 Met Met Arg Arg Pro Val His Cys Ala Thr Asp Lys Glu Gly Ile Leu
   1               5                  10                  15    
 Ala Pro Lys His Phe Gln Ala Ala Ala Gly Glu Ala Arg Thr Ser Thr
              20                  25                  30        
 Asp Arg Ser Gly Ala Gln Ala Gln Arg Ser Val Thr Pro Cys Gln Trp
          35                  40                  45            
 His Ser Val Gln Asp Ser Ser Thr Tyr Ser Ser Val Val Val Val Val
      50                  55                  60                
 Val Ala Ala Ala Ala Glu Thr Leu
  65                  70        



      <210> 2536
      <211> 179
      <212> PRT
      <213> Homo sapiens


      <400> 2536
 Pro Ala Asp Ala Pro Ser Leu Ala Ala Phe Pro Gly Asp Pro Gln Tyr
   1               5                  10                  15    
 Asp Pro Pro Tyr Cys Tyr Pro Gly Thr Gln Cys Trp Val Pro Gly Glu
              20                  25                  30        
 Gly Met Leu Leu Leu Ser Gln Thr Leu Cys Leu Gly Glu Gln Val Leu
          35                  40                  45            
 Leu Gly Ala Trp Leu Val Trp Gly Pro Ser Arg Asp Pro Arg Pro Leu
      50                  55                  60                
 Pro Tyr Leu Cys His Asp Glu Pro Tyr Thr Phe Asp Ile Asn Leu Ser
  65                  70                  75                  80
 Val Asn Leu Lys Gly Pro Gly Asn Arg Leu Gly Glu Pro Ile Pro Ile
                  85                  90                  95    
 Ser Lys Ala His Glu His Ile Phe Gly Met Val Leu Met Asn Asp Trp
             100                 105                 110        
 Ser Gly Asn Tyr Trp Ser Ser Val Pro Val Lys Met Thr Gly Lys Glu
         115                 120                 125            
 Leu Gly Thr Trp Gly Asn Phe Ile Lys Ala Glu Asp Trp Cys Arg Ser
     130                 135                 140                
 Lys Gly Ala Val Met Ala Leu Pro Arg Ala Val Thr Pro Thr Arg Ala
 145                 150                 155                 160
 Ile Asn Glu Ser Thr Ile Gly Ala Ala Gly Val Asp Asn Glu Val Ser
                 165                 170                 175    
 Ser Thr Gly
            



      <210> 2537
      <211> 544
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(544)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2537
 Asn His Lys Ser Pro Met Ala Leu Pro Tyr His Ile Phe Leu Phe Thr
   1               5                  10                  15    
 Val Leu Leu Pro Ser Phe Thr Leu Thr Ala Pro Pro Pro Cys Arg Cys
              20                  25                  30        
 Met Thr Ser Ser Ser Pro Tyr Gln Glu Phe Leu Trp Arg Met Gln Arg
          35                  40                  45            
 Pro Gly Asn Ile Asp Ala Pro Ser Tyr Arg Ser Leu Ser Lys Gly Thr
      50                  55                  60                
 Pro Thr Phe Thr Ala His Thr His Met Pro Arg Asn Cys Tyr His Ser
  65                  70                  75                  80
 Ala Thr Leu Cys Met His Ala Asn Thr His Tyr Trp Thr Gly Lys Met
                  85                  90                  95    
 Ile Asn Pro Ser Cys Pro Gly Gly Leu Gly Val Thr Val Cys Arg Thr
             100                 105                 110        
 Tyr Phe Thr Gln Thr Gly Met Ser Asp Gly Gly Gly Val Gln Asp Gln
         115                 120                 125            
 Ala Arg Glu Lys His Val Lys Glu Ala Ile Ser Gln Leu Thr Arg Gly
     130                 135                 140                
 His Ser Thr Pro Ser Pro Tyr Lys Gly Leu Val Leu Ser Lys Leu His
 145                 150                 155                 160
 Glu Thr Leu Arg Thr His Thr Arg Leu Val Ser Leu Phe Asn Thr Thr
                 165                 170                 175    
 Leu Thr Gly Leu His Glu Val Ser Ala Gln Asn Pro Thr Asn Cys Trp
             180                 185                 190        
 Ile Cys Leu Pro Leu Asn Phe Arg Pro Tyr Val Ser Ile Pro Val Pro
         195                 200                 205            
 Glu Gln Trp Asn Asn Phe Ser Thr Glu Ile Asn Thr Thr Ser Val Leu
     210                 215                 220                
 Val Gly Pro Leu Val Ser Asn Leu Glu Ile Thr His Thr Ser Asn Leu
 225                 230                 235                 240
 Thr Cys Val Lys Phe Ser Asn Thr Thr Tyr Thr Thr Asn Ser Gln Cys
                 245                 250                 255    
 Ile Arg Trp Val Thr Pro Pro Thr Gln Ile Val Cys Leu Pro Ser Gly
             260                 265                 270        
 Ile Phe Phe Val Cys Gly Thr Ser Ala Tyr Arg Cys Leu Asn Gly Ser
         275                 280                 285            
 Ser Glu Ser Met Cys Phe Leu Ser Phe Leu Val Pro Pro Met Thr Ile
     290                 295                 300                
 Tyr Thr Glu Gln Asp Leu Tyr Ser Tyr Val Ile Ser Xaa Ser Pro Arg
 305                 310                 315                 320
 Asn Lys Arg Val Pro Ile Leu Pro Phe Val Ile Gly Ala Gly Val Leu
                 325                 330                 335    
 Gly Gly Leu Gly Thr Gly Ile Gly Gly Ile Thr Thr Ser Thr Gln Phe
             340                 345                 350        
 Tyr His Lys Leu Ser Gln Glu Leu Asn Gly Asp Met Glu Gln Val Ala
         355                 360                 365            
 Asp Ser Leu Val Thr Leu Gln Asp Gln Leu Asn Ser Leu Ala Ala Val
     370                 375                 380                
 Val Leu Gln Asn Arg Arg Ala Leu Asp Leu Leu Thr Ala Glu Arg Gly
 385                 390                 395                 400
 Gly Thr Cys Leu Leu Leu Gly Glu Glu Cys Cys Tyr Tyr Val Asn Gln
                 405                 410                 415    
 Ser Gly Ile Val Thr Glu Lys Val Lys Glu Ile Arg Asp Arg Ile Gln
             420                 425                 430        
 Arg Arg Ala Glu Glu Leu Arg Asn Thr Gly Pro Trp Gly Leu Leu Ser
         435                 440                 445            
 Gln Trp Met Pro Trp Ile Leu Pro Phe Leu Gly Pro Leu Ala Ala Ile
     450                 455                 460                
 Ile Leu Leu Leu Leu Phe Gly Pro Cys Ile Phe Asn Leu Leu Val Asn
 465                 470                 475                 480
 Phe Val Ser Ser Arg Ile Glu Ala Val Lys Leu Gln Met Glu Pro Lys
                 485                 490                 495    
 Met Gln Ser Lys Thr Lys Ile Tyr Arg Arg Pro Leu Asp Arg Pro Ala
             500                 505                 510        
 Ser Pro Arg Ser Asp Val Asn Asp Ile Lys Gly Thr Pro Pro Glu Glu
         515                 520                 525            
 Ile Ser Ala Ala Gln Pro Leu Leu Arg Pro Asn Ser Ala Gly Ser Ser
     530                 535                 540                





      <210> 2538
      <211> 20
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(20)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2538
 Xaa Tyr Cys Arg Val Pro Thr Tyr Phe His Met Thr Pro Tyr Glu Gly
   1               5                  10                  15    
 Thr Thr Ser Thr
              20



      <210> 2539
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 2539
 Gly Gly Ile Gly Arg Gly Gly Gly Ala Gly Gly Gly Val Gly Ala Ala
   1               5                  10                  15    
 Gly Ser Ala Ser Gly Gly Val Gly Arg Arg Gly Ala Gly Gly Val Ile
              20                  25                  30        
 Ala Asp Ser Gly Ala Pro Gly Gly Gly Val Glu Gly Gly Val Gly Ala
          35                  40                  45            
 Ser Gly Gly Trp Arg Glu Gly Arg Gly Thr Ser Gly Gly Val Gly Gly
      50                  55                  60                
 Ser Gly Gly Ala Cys Gly Ser Val Gly Gly Ser Gly Gly Ala Gly Gly
  65                  70                  75                  80
 Gly Val Gly Ala Cys Gly Ser Thr Ser Asp Gly Val Gly Arg Ser Arg
                  85                  90                  95    
 Gly Thr Ile Gly Gly Leu Gly Gly Ser Gly Ser Ala Gly Gly Gly Val
             100                 105                 110        
 Gly Ala Cys Gly Gly Ala Ser Gly Tyr Val Gly Ile Arg Gly Ala Gly
         115                 120                 125            
 Gly Gly
     130



      <210> 2540
      <211> 122
      <212> PRT
      <213> Homo sapiens


      <400> 2540
 Ala Arg Asp Pro Leu Leu Glu Gln Val Glu Leu Pro Ala Val Ala Ser
   1               5                  10                  15    
 Val Ser Ala Ser Val Ile Lys Ser Pro Ser Asp Pro Ser His Val Ser
              20                  25                  30        
 Val Pro Pro Pro Pro Leu Leu Leu Pro Ala Ala Thr Thr Arg Ser Asn
          35                  40                  45            
 Ser Thr Ser Met His Ser Ser Ile Pro Ser Ile Glu Asn Lys Pro Pro
      50                  55                  60                
 Gln Ala Ile Val Lys Pro Gln Ile Leu Thr His Val Ile Glu Gly Phe
  65                  70                  75                  80
 Val Ile Gln Glu Gly Leu Glu Pro Phe Pro Val Ser Arg Ser Ser Leu
                  85                  90                  95    
 Leu Ile Glu Gln Pro Val Lys Lys Arg Pro Leu Leu Asp Asn Gln Val
             100                 105                 110        
 Ile Asn Ser Val Cys Val Gln Pro Glu Leu
         115                 120        



      <210> 2541
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 2541
 Met Trp Ser Ala His Pro Leu Ala Val Leu Ser Leu Lys Leu Thr Leu
   1               5                  10                  15    
 Phe Ser Leu Thr Ser Asp Trp Leu Ser Ser Lys Asp Met Ala Ile Ser
              20                  25                  30        
 Leu Ala Phe Lys Ile Ser Gln Ile Leu Cys Ser Val Leu Ser Ala Pro
          35                  40                  45            
 Gly Lys Arg Leu Ile Ser Val Leu Trp Asn Thr Ser Ser Leu Lys Arg
      50                  55                  60                
 Ser
  65



      <210> 2542
      <211> 1276
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1276)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2542
 His Pro Leu Asp Ile His Thr Ile Leu Leu Ala Ala Gly Phe Leu Gly
   1               5                  10                  15    
 Leu Arg Thr Val Gly Val Thr Lys Ala Trp Arg Ser Gly Trp Leu Arg
              20                  25                  30        
 Phe Pro Ala Ala Met Phe Leu Tyr Asn Leu Thr Leu Gln Arg Ala Thr
          35                  40                  45            
 Gly Ile Ser Phe Ala Ile His Gly Asn Phe Ser Gly Thr Lys Gln Gln
      50                  55                  60                
 Glu Ile Val Val Ser Arg Gly Lys Ile Leu Glu Leu Leu Arg Pro Asp
  65                  70                  75                  80
 Pro Asn Thr Gly Lys Val His Thr Leu Leu Thr Val Glu Val Phe Gly
                  85                  90                  95    
 Val Ile Arg Ser Leu Met Ala Phe Arg Leu Thr Gly Gly Thr Lys Asp
             100                 105                 110        
 Tyr Ile Val Val Gly Ser Asp Ser Gly Arg Ile Val Ile Leu Glu Tyr
         115                 120                 125            
 Gln Pro Ser Lys Asn Met Phe Glu Lys Ile His Gln Glu Thr Phe Gly
     130                 135                 140                
 Lys Ser Gly Gly Arg Ser Ile Val Pro Gly Gln Phe Leu Ala Val Asp
 145                 150                 155                 160
 Pro Lys Gly Arg Ala Val Met Ile Ser Ala Ile Glu Lys Gln Lys Leu
                 165                 170                 175    
 Val Tyr Ile Leu Asn Arg Asp Ala Ala Ala Arg Leu Thr Ile Ser Ser
             180                 185                 190        
 Pro Leu Glu Ala His Lys Ala Asn Thr Leu Val Tyr His Val Val Gly
         195                 200                 205            
 Val Asp Val Gly Phe Glu Asn Pro Met Phe Ala Cys Leu Glu Met Asp
     210                 215                 220                
 Tyr Glu Glu Ala Asp Asn Asp Pro Thr Gly Glu Ala Ala Ala Asn Thr
 225                 230                 235                 240
 Gln Gln Thr Leu Thr Phe Tyr Glu Leu Asp Leu Gly Leu Asn His Val
                 245                 250                 255    
 Val Arg Lys Tyr Ser Glu Pro Leu Glu Glu His Gly Asn Phe Leu Ile
             260                 265                 270        
 Thr Val Pro Gly Gly Ser Asp Gly Pro Ser Gly Val Leu Ile Cys Ser
         275                 280                 285            
 Glu Asn Tyr Ile Thr Tyr Lys Asn Phe Gly Asp Gln Pro Asp Ile Arg
     290                 295                 300                
 Cys Pro Ile Pro Arg Arg Arg Asn Asp Leu Asp Asp Pro Glu Arg Gly
 305                 310                 315                 320
 Met Ile Phe Val Cys Ser Ala Thr His Lys Thr Lys Ser Met Phe Phe
                 325                 330                 335    
 Phe Leu Ala Gln Thr Glu Gln Gly Asp Ile Phe Lys Ile Thr Leu Glu
             340                 345                 350        
 Thr Asp Glu Asp Met Val Thr Glu Ile Arg Leu Lys Tyr Phe Asp Thr
         355                 360                 365            
 Val Pro Val Ala Ala Ala Met Cys Val Leu Lys Thr Gly Phe Leu Phe
     370                 375                 380                
 Val Ala Ser Glu Phe Gly Asn His Tyr Leu Tyr Gln Ile Ala His Leu
 385                 390                 395                 400
 Gly Asp Asp Asp Glu Glu Pro Glu Phe Ser Ser Ala Met Pro Leu Glu
                 405                 410                 415    
 Glu Gly Asp Thr Phe Phe Phe Gln Pro Arg Pro Leu Lys Asn Leu Val
             420                 425                 430        
 Leu Val Asp Glu Leu Asp Ser Leu Ser Pro Ile Leu Phe Cys Gln Ile
         435                 440                 445            
 Ala Asp Leu Ala Asn Glu Asp Thr Pro Gln Leu Tyr Val Ala Cys Gly
     450                 455                 460                
 Arg Gly Pro Arg Ser Ser Leu Arg Val Leu Arg His Gly Leu Glu Val
 465                 470                 475                 480
 Ser Glu Met Ala Val Ser Glu Leu Pro Gly Asn Pro Asn Ala Val Trp
                 485                 490                 495    
 Thr Val Arg Arg His Ile Glu Asp Glu Phe Asp Ala Tyr Ile Ile Val
             500                 505                 510        
 Ser Phe Val Asn Ala Thr Leu Val Leu Ser Ile Gly Glu Thr Val Glu
         515                 520                 525            
 Glu Val Thr Asp Ser Gly Phe Leu Gly Thr Thr Pro Thr Leu Ser Cys
     530                 535                 540                
 Ser Leu Leu Gly Asp Asp Ala Leu Val Gln Val Tyr Pro Asp Gly Ile
 545                 550                 555                 560
 Arg His Ile Arg Ala Asp Lys Arg Val Asn Glu Trp Lys Thr Pro Gly
                 565                 570                 575    
 Lys Lys Thr Ile Val Lys Cys Ala Val Asn Gln Arg Gln Val Val Ile
             580                 585                 590        
 Ala Leu Thr Gly Gly Glu Leu Val Tyr Phe Glu Met Asp Pro Ser Gly
         595                 600                 605            
 Gln Leu Asn Glu Tyr Thr Glu Arg Lys Glu Met Ser Ala Asp Val Val
     610                 615                 620                
 Cys Met Ser Leu Ala Asn Val Pro Pro Gly Glu Gln Arg Ser Arg Phe
 625                 630                 635                 640
 Leu Ala Val Gly Leu Val Asp Asn Thr Val Arg Ile Ile Ser Leu Asp
                 645                 650                 655    
 Pro Ser Asp Cys Leu Gln Pro Leu Ser Met Gln Ala Leu Pro Ala Gln
             660                 665                 670        
 Pro Glu Ser Leu Cys Ile Val Glu Met Gly Gly Thr Xaa Lys Gln Asp
         675                 680                 685            
 Glu Leu Gly Glu Arg Gly Ser Ile Gly Phe Leu Tyr Leu Asn Ile Gly
     690                 695                 700                
 Leu Gln Asn Gly Val Leu Leu Arg Thr Val Leu Asp Pro Val Thr Gly
 705                 710                 715                 720
 Asp Leu Ser Asp Thr Arg Thr Arg Tyr Leu Gly Ser Arg Pro Val Lys
                 725                 730                 735    
 Leu Phe Arg Val Arg Met Gln Gly Gln Glu Ala Val Leu Ala Met Ser
             740                 745                 750        
 Ser Arg Ser Trp Leu Ser Tyr Ser Tyr Gln Ser Arg Phe His Leu Thr
         755                 760                 765            
 Pro Leu Ser Tyr Glu Thr Leu Glu Phe Ala Ser Gly Phe Ala Ser Glu
     770                 775                 780                
 Gln Cys Pro Glu Gly Ile Val Ala Ile Ser Thr Asn Thr Leu Arg Ile
 785                 790                 795                 800
 Leu Ala Leu Glu Lys Leu Gly Ala Val Phe Asn Gln Val Ala Phe Pro
                 805                 810                 815    
 Leu Gln Tyr Thr Pro Arg Lys Phe Val Ile His Pro Glu Ser Asn Asn
             820                 825                 830        
 Leu Ile Ile Ile Glu Thr Asp His Asn Ala Tyr Thr Glu Ala Thr Lys
         835                 840                 845            
 Ala Gln Arg Lys Gln Gln Met Ala Glu Glu Met Val Glu Ala Ala Trp
     850                 855                 860                
 Glu Asp Glu Arg Asp Leu Ala Ala Glu Met Ala Ala Ala Phe Leu Asn
 865                 870                 875                 880
 Glu Asn Leu Pro Glu Ser Ile Phe Gly Ala Pro Lys Ala Gly Asn Gly
                 885                 890                 895    
 Gln Leu Ala Ser Val Ile Arg Val Met Asn Pro Ile Gln Gly Glu His
             900                 905                 910        
 Thr Trp Thr Leu Ser Ser Leu Glu Gln Asn Arg Ala Ala Phe Ser Val
         915                 920                 925            
 Ala Val Cys Arg Phe Ser Asn Thr Gly Asp Asp Trp Tyr Val Leu Val
     930                 935                 940                
 Gly Val Pro Lys Asp Leu Ile Leu Asn Pro Arg Ser Val Ala Gly Gly
 945                 950                 955                 960
 Phe Val Tyr Thr Tyr Lys Leu Val Asn Asn Gly Glu Lys Leu Glu Phe
                 965                 970                 975    
 Leu His Lys Thr Pro Val Glu Glu Val Pro Ala Ala Ile Ala Pro Phe
             980                 985                 990        
 Gln Gly Arg Val Leu Ile Gly Val Gly Lys Leu Leu Arg Val Tyr Asp
         995                1000                1005            
 Leu Gly Lys Glu Gly Ser Tyr Phe Arg Lys Cys Xaa Glu Leu Arg His
    1010                1015                1020                
 Ile Ala Asn Tyr Ile Ser Gly Asp Pro Asp Tyr Ser Gly His Arg Val
1025                1030                1035                1040
 Ile Val Ser Asp Val Gln Glu Lys Phe His Pro Gly Phe Arg Tyr Lys
                1045                1050                1055    
 Arg Lys Leu Lys Thr Lys Leu Ile Ile Phe Ala Asp Asp Thr Tyr Pro
            1060                1065                1070        
 Arg Trp Val His Tyr Arg Pro Ala Ser Trp Asp Tyr Asp Thr Val Gly
        1075                1080                1085            
 Trp Gly Gln Asp Lys Phe Arg Pro Thr Tyr Val Trp Val Arg Leu Pro
    1090                1095                1100                
 Thr Leu Thr Pro Ile Asp Glu Val Arg Asp Glu Asp Pro Thr Gly Asn
1105                1110                1115                1120
 Lys Ser Pro Val Gly Thr Arg Gly Leu Ala Gln Met Gly Gly Leu Pro
                1125                1130                1135    
 Arg Lys Ala Glu Val Ile Ile Glu Leu Thr His Val Gly Glu Thr Val
            1140                1145                1150        
 Leu Ser Leu Gln Lys Thr Thr Leu Ile Pro Gly Arg Leu Gln Asn Ser
        1155                1160                1165            
 Leu Val Leu Leu Pro Pro Cys Phe Gly Gly Ile Gly Ile Leu Val Pro
    1170                1175                1180                
 Phe Thr Ser His Glu Asp His Asp Phe Phe Gln His Val Glu Met His
1185                1190                1195                1200
 Leu Arg Ser Glu His Pro Pro Leu Cys Gly Gly Gly Asp His Leu Ser
                1205                1210                1215    
 Phe Arg Ser Tyr Tyr Phe Pro Cys Glu Gly Met Xaa Leu Met Gly Asp
            1220                1225                1230        
 Leu Cys Glu Gln Phe Asn Ser Met Glu Pro Asn Lys Gln Lys Glu Arg
        1235                1240                1245            
 Leu Leu Lys Glu Leu Gly Pro Glu Pro Pro Pro Arg Ser Val Pro Arg
    1250                1255                1260                
 Lys Phe Glu Gly Tyr Ser Gly Thr Arg Tyr Gly Phe
1265                1270                1275    



      <210> 2543
      <211> 119
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(119)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2543
 Ser His Ile Leu Pro Gly Ala Pro Gly Ala Pro Ala Trp Trp Thr Arg
   1               5                  10                  15    
 Trp Pro Ser Thr Leu Pro Glu Pro Phe Pro Arg Gly Arg Gly Ser Pro
              20                  25                  30        
 Ala Gly Thr Ser Pro Ile Ser Arg Pro Gly Leu Val Gln Ser Ser Xaa
          35                  40                  45            
 Ala Ser Arg Gly Ser Asp Ser Arg Leu Pro Val Gly Pro Ala Ser Cys
      50                  55                  60                
 Gln Ala Ser Gly Pro Gly Pro Asp Ser Arg Arg Pro Pro Pro Cys Thr
  65                  70                  75                  80
 Pro Ala Gly Pro His His Gly Ser Leu Pro Ser Ala Gly Arg Val Gly
                  85                  90                  95    
 Ala Ser Ala Ala Ala Ala Gly Pro Pro Ser Pro Ala Val Pro Leu Pro
             100                 105                 110        
 Pro Ala Glu Arg Pro Ala Pro
         115                



      <210> 2544
      <211> 658
      <212> PRT
      <213> Homo sapiens


      <400> 2544
 Asp Ala Glu Arg Gln Glu Ala Leu Gly Ile Val Arg Arg Ile Gly Thr
   1               5                  10                  15    
 Asp Thr Glu Ala Ala Thr Glu Pro Ala Gly Ala Thr Val Pro Ala Ala
              20                  25                  30        
 Ala Ala Ala Ala Arg Ile Gly Thr Val Gly Pro Gln Pro Pro Ala Met
          35                  40                  45            
 Pro Arg Arg Lys Arg Asn Ala Gly Ser Ser Ser Asp Gly Thr Glu Asp
      50                  55                  60                
 Ser Asp Phe Ser Thr Asp Leu Glu His Thr Asp Ser Ser Glu Ser Asp
  65                  70                  75                  80
 Gly Thr Ser Arg Arg Ser Ala Arg Val Thr Arg Ser Ser Ala Arg Leu
                  85                  90                  95    
 Ser Gln Ser Ser Gln Asp Ser Ser Pro Val Arg Asn Leu Gln Ser Phe
             100                 105                 110        
 Gly Thr Glu Glu Pro Ala Tyr Ser Thr Arg Arg Val Thr Arg Ser Gln
         115                 120                 125            
 Gln Gln Pro Thr Pro Val Thr Pro Lys Lys Tyr Pro Leu Arg Gln Thr
     130                 135                 140                
 Arg Ser Ser Gly Ser Glu Thr Glu Gln Val Val Asp Phe Ser Asp Arg
 145                 150                 155                 160
 Glu Thr Lys Asn Thr Ala Asp His Asp Glu Ser Pro Pro Arg Thr Pro
                 165                 170                 175    
 Thr Gly Asn Ala Pro Ser Ser Glu Ser Asp Ile Asp Ile Ser Ser Pro
             180                 185                 190        
 Asn Val Ser His Asp Glu Ser Ile Ala Lys Asp Met Ser Leu Lys Asp
         195                 200                 205            
 Ser Gly Ser Asp Leu Ser His Arg Pro Lys Arg Arg Arg Phe His Glu
     210                 215                 220                
 Ser Tyr Asn Phe Asn Met Lys Cys Pro Thr Pro Gly Cys Asn Ser Leu
 225                 230                 235                 240
 Gly His Leu Thr Gly Lys His Glu Arg His Phe Ser Ile Ser Gly Cys
                 245                 250                 255    
 Pro Leu Tyr His Asn Leu Ser Ala Asp Glu Cys Lys Val Arg Ala Gln
             260                 265                 270        
 Thr Arg Asp Lys Gln Ile Glu Glu Arg Met Leu Ser His Arg Gln Asp
         275                 280                 285            
 Asp Asn Asn Arg His Ala Thr Arg His Gln Ala Pro Thr Glu Arg Gln
     290                 295                 300                
 Leu Arg Tyr Lys Glu Lys Val Ala Glu Leu Lys Lys Lys Arg Asn Ser
 305                 310                 315                 320
 Gly Leu Ser Lys Glu Gln Lys Glu Lys Tyr Met Glu His Arg Gln Thr
                 325                 330                 335    
 Tyr Gly Asn Thr Arg Glu Pro Leu Leu Glu Asn Leu Thr Ser Glu Tyr
             340                 345                 350        
 Asp Leu Asp Leu Phe Arg Arg Ala Gln Ala Arg Ala Ser Glu Asp Leu
         355                 360                 365            
 Glu Lys Leu Arg Leu Gln Gly Gln Ile Thr Glu Gly Ser Asn Met Ile
     370                 375                 380                
 Lys Thr Ile Ala Phe Gly Arg Tyr Glu Leu Asp Thr Trp Tyr His Ser
 385                 390                 395                 400
 Pro Tyr Pro Glu Glu Tyr Ala Arg Leu Gly Arg Leu Tyr Met Cys Glu
                 405                 410                 415    
 Phe Cys Leu Lys Tyr Met Lys Ser Gln Thr Ile Leu Arg Arg His Met
             420                 425                 430        
 Ala Lys Cys Val Trp Lys His Pro Pro Gly Asp Glu Ile Tyr Arg Lys
         435                 440                 445            
 Gly Ser Ile Ser Val Phe Glu Val Asp Gly Lys Lys Asn Lys Ile Tyr
     450                 455                 460                
 Cys Gln Asn Leu Cys Leu Leu Ala Lys Leu Phe Leu Asp His Lys Thr
 465                 470                 475                 480
 Leu Tyr Tyr Asp Val Glu Pro Phe Leu Phe Tyr Val Met Thr Glu Ala
                 485                 490                 495    
 Asp Asn Thr Gly Cys His Leu Ile Gly Tyr Phe Ser Lys Glu Lys Asn
             500                 505                 510        
 Ser Phe Leu Asn Tyr Asn Val Ser Cys Ile Leu Thr Met Pro Gln Tyr
         515                 520                 525            
 Met Arg Gln Gly Tyr Gly Lys Met Leu Ile Asp Phe Ser Tyr Leu Leu
     530                 535                 540                
 Ser Lys Val Glu Glu Lys Val Gly Ser Pro Glu Arg Pro Leu Ser Asp
 545                 550                 555                 560
 Leu Gly Leu Ile Ser Tyr Arg Ser Tyr Trp Lys Glu Val Leu Leu Arg
                 565                 570                 575    
 Tyr Leu His Asn Phe Gln Gly Lys Glu Ile Ser Ile Lys Glu Ile Ser
             580                 585                 590        
 Gln Glu Thr Ala Val Asn Pro Val Asp Ile Val Ser Thr Leu Gln Ala
         595                 600                 605            
 Leu Gln Met Leu Lys Tyr Trp Lys Gly Lys His Leu Val Leu Lys Arg
     610                 615                 620                
 Gln Asp Leu Ile Asp Glu Trp Ile Ala Lys Glu Ala Lys Arg Ser Asn
 625                 630                 635                 640
 Ser Asn Lys Thr Met Asp Pro Ser Cys Leu Lys Trp Thr Pro Pro Lys
                 645                 650                 655    
 Gly Thr
        



      <210> 2545
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 2545
 Val Trp Pro Glu Val Thr Asp Pro Glu Lys Phe Val Tyr Glu Asp Val
   1               5                  10                  15    
 Ala Ile Ala Ala Tyr Leu Leu Ile Leu Trp Glu Glu Glu Arg Ala Glu
              20                  25                  30        
 Arg Gly Leu Thr Ala Arg Gln Ser Phe Val Asp Leu Gly Cys Gly Asn
          35                  40                  45            
 Gly Leu Leu Val His Ile Leu Ser Ser Glu Gly His Pro Gly Arg Gly
      50                  55                  60                
 Ile Asp Val Arg Arg Arg Lys Ile Trp Asp Met Tyr Gly Pro Gln Thr
  65                  70                  75                  80
 Gln Leu Glu Glu Asp Ala Ile Thr Pro Asn Asp Lys Thr Leu Phe Pro
                  85                  90                  95    
 Asp Val Asp Trp Leu Ile Gly Asn His Ser Asp Glu Leu Thr Pro Trp
             100                 105                 110        
 Ile Pro Val Ile Ala Ala Arg Ser Ser Tyr Asn Cys Arg Phe Phe Val
         115                 120                 125            
 Leu Pro Cys Cys Phe Phe Asp Phe Ile Gly Arg Tyr Ser Arg Arg Gln
     130                 135                 140                
 Ser Lys Lys Thr Gln Tyr Arg Glu Tyr Leu Asp Phe Ile Lys Glu Val
 145                 150                 155                 160
 Gly Phe Thr Cys Gly Phe His Val Asp Glu Asp Cys Leu Arg Ile Pro
                 165                 170                 175    
 Ser Thr Thr Arg Val Cys Leu Val Gly Lys Ser Arg Thr Tyr Pro Tyr
             180                 185                 190        
 Ser Ile Glu Ala Ser Val Asp Glu Lys Arg Thr Gln Tyr Ile Lys Ser
         195                 200                 205            





      <210> 2546
      <211> 68
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(68)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2546
 Xaa Pro Phe Leu Ile Leu Leu Leu Ser Pro Val Ser Thr Asp Gln Ala
   1               5                  10                  15    
 Asn Thr Thr Thr Ala Glu Ile His Ser Gln Leu Thr Pro Arg Leu Asn
              20                  25                  30        
 Leu Thr Ile Leu Ser Ser Gln Gly Ala Ser Leu Gln Gln Arg Val Thr
          35                  40                  45            
 Tyr His Arg Asn His Lys Tyr Gly Gln Thr His Pro Gln Lys Ala Glu
      50                  55                  60                
 Ile Val Val Gly
  65            



      <210> 2547
      <211> 92
      <212> PRT
      <213> Homo sapiens


      <400> 2547
 Gly Leu Ala Ala Gly Leu Pro Glu Thr Leu His Ile Ser Tyr Cys Met
   1               5                  10                  15    
 Thr Val Phe Arg Phe Glu Ser Leu Asp Ser Gly Val Trp Thr Asp Asp
              20                  25                  30        
 His Ser Glu Ala Cys Arg Asn Met His Val Leu Ser Val Trp Thr Ala
          35                  40                  45            
 Ser Cys Lys Ala Glu Pro Asn Pro Ile Trp Pro His His Pro Trp Leu
      50                  55                  60                
 Ser Cys Ala Thr Trp Pro Cys Trp Lys Gly Phe Asp Leu Pro Gly Ile
  65                  70                  75                  80
 Cys Phe Thr Ala Leu Ser Cys Pro Lys Ile Tyr Ala
                  85                  90        



      <210> 2548
      <211> 535
      <212> PRT
      <213> Homo sapiens


      <400> 2548
 Pro Met Tyr Leu Phe Leu Cys Pro Pro Leu Ala Leu Val Gln Cys Ala
   1               5                  10                  15    
 Leu Lys Asp Pro Arg Ser Lys Tyr Ser Leu Gly Gly Arg Thr Thr Leu
              20                  25                  30        
 Ile Ile Thr Leu Gln Gly Ser Gly Lys Lys Asn Asn Ile Pro His Pro
          35                  40                  45            
 Ser Ser Leu Ser Glu Arg Val Met Thr Ala Lys Asp Gly Phe Val Ser
      50                  55                  60                
 Arg Cys His Leu Leu Met Gln Pro Lys Gln Gln Lys Trp Ser Leu Met
  65                  70                  75                  80
 Tyr Pro Met Glu Gly Glu Val Leu Glu Asn Gly Cys Trp Pro Thr Leu
                  85                  90                  95    
 Gln Asp Ser Leu Leu Cys Thr Ala Leu Val Asp Lys Leu Leu Val Phe
             100                 105                 110        
 Leu Gly Arg Cys Phe Cys Thr Ala Val Glu Val Val Met Leu Val Thr
         115                 120                 125            
 Cys Arg Thr Ala Ala Ala Val Ser Ala Phe Leu Ile Val Gly Arg Val
     130                 135                 140                
 Ser Ser Pro Val Cys Arg Ala Val Ser Val Gln Pro Trp Thr Leu Thr
 145                 150                 155                 160
 Ala Asp His Thr Pro Gly Arg Tyr Cys Leu Lys Leu Val Cys Arg Gln
                 165                 170                 175    
 Leu Cys Leu Cys Pro Ser Ser Thr Pro Leu Thr Glu Val Phe Cys Ser
             180                 185                 190        
 Lys Glu Ala Phe Phe Ile Ile Leu Asp Cys Ser Asn Leu Pro His Ala
         195                 200                 205            
 Leu Leu Pro Val Asp Ser Pro Lys Gly Leu Ser Lys Cys Ser Asn Pro
     210                 215                 220                
 Arg Glu Lys Ala Arg Arg Lys Leu Gln Gly His Tyr His Val Ala Ser
 225                 230                 235                 240
 Glu Val Ser Phe Val Pro Val Arg Arg Phe Pro Lys Gly Glu Ile Gly
                 245                 250                 255    
 Ala Asn Gln Pro Gly Thr His Arg Lys Phe Tyr His Leu Thr His Tyr
             260                 265                 270        
 Arg Gln Asn Leu Lys Gln Pro Asp Val Pro His Gly Arg Ile Val Phe
         275                 280                 285            
 Asp Asp Lys Asp Ile Thr Asp Trp Gln Thr Ala Lys Ile Met Arg Glu
     290                 295                 300                
 Ala Val Ala Ile Val Pro Glu Gly Arg Arg Val Phe Ser Arg Met Thr
 305                 310                 315                 320
 Val Glu Glu Asn Leu Ala Met Gly Gly Phe Phe Ala Glu Arg Asp Gln
                 325                 330                 335    
 Phe Gln Glu Arg Ile Lys Trp Val Tyr Glu Leu Phe Pro Arg Leu His
             340                 345                 350        
 Glu Arg Arg Ile Gln Arg Ala Gly Thr Met Ser Gly Gly Glu Gln Gln
         355                 360                 365            
 Met Leu Ala Ile Gly Arg Ala Leu Met Ser Asn Pro Arg Leu Leu Leu
     370                 375                 380                
 Leu Asp Glu Pro Ser Leu Gly Leu Ala Pro Ile Ile Ile Gln Gln Ile
 385                 390                 395                 400
 Phe Asp Thr Ile Glu Gln Leu Arg Glu Gln Gly Met Thr Ile Phe Leu
                 405                 410                 415    
 Val Glu Gln Asn Ala Asn Gln Ala Leu Lys Leu Ala Asp Arg Gly Tyr
             420                 425                 430        
 Val Leu Glu Asn Gly His Val Val Leu Ser Asp Thr Gly Asp Ala Leu
         435                 440                 445            
 Leu Ala Asn Glu Ala Val Arg Arg Gly Asp Glu Leu Thr Glu Asp Arg
     450                 455                 460                
 Ser Arg Ser Leu Asp Gly Glu Leu Ile Arg Ser Leu Pro Cys Gly Ala
 465                 470                 475                 480
 Ser Tyr Gly Gly Leu Ser Leu Arg Pro Trp Ser Arg Gly His Ile Pro
                 485                 490                 495    
 Gln Ser His Gln Ser Ser Glu Ser Val Arg Val Met Phe Ile Asn Thr
             500                 505                 510        
 Ser Lys Gly Ala Ser Ile Ile Ser Ser Ser Ala Thr Met Pro Gly Pro
         515                 520                 525            
 Leu Pro Lys His Leu Gly Pro
     530                 535



      <210> 2549
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 2549
 Met His Val Gln Gly Lys Ala Ala Ile Leu Gly Arg His Phe Ser Ile
   1               5                  10                  15    
 Ser Ser Leu Leu Pro Gly Ala Leu Leu Leu Leu Thr Val Ile Lys Gly
              20                  25                  30        
 His Thr His Pro Glu Glu Lys Ser Pro Gly Ala His Glu Lys Ala Val
          35                  40                  45            
 Thr Gly Glu Pro Lys Cys Leu Gly Ala Leu Pro Tyr Cys Asp Ser Gly
      50                  55                  60                
 Gly Lys Lys Ala Thr Lys Lys Lys Asp Ala Gly Glu Met Arg Ser Arg
  65                  70                  75                  80
 Ile Lys Asp Gly Val Leu Val Leu Lys Cys Ile Ser Leu Gln Val Gly
                  85                  90                  95    
 Leu Ala Ser Trp Ile Val Ser Trp Leu Arg Thr Glu Ala Thr Gly Tyr
             100                 105                 110        
 Thr Phe Ala Leu Leu Pro Pro Gly Thr His His Thr Glu Gln Thr Pro
         115                 120                 125            
 Ser Lys His Glu Gln Asn Gly Ala Glu Leu Phe Cys Asn Cys Val Ser
     130                 135                 140                
 Cys Phe Glu Asp Pro Cys Pro Cys Gln Val Pro Gly Thr Gln Pro Gly
 145                 150                 155                 160
 Asn Arg Leu Ser Glu Glu His Gln Ala Ser Ser Gln Ala Asp Val Thr
                 165                 170                 175    
 Asn Ser Ser Ala Pro Lys Gln Pro His Pro Pro Pro Ala Pro Cys Lys
             180                 185                 190        
 Gly Val Cys Ser His Cys
         195            



      <210> 2550
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 2550
 Met Ala Gly Thr Ala Gln Leu Leu Gly Leu Lys Gln Leu Ile Gly Leu
   1               5                  10                  15    
 Glu Leu Leu Thr Ala Gln Cys Gly Gln Ile Thr Gly Tyr Arg Asp Arg
              20                  25                  30        
 Arg Glu Glu Leu Leu Pro Pro Arg Phe Leu Ala Thr Gly Pro Pro Ser
          35                  40                  45            
 Cys His Pro Pro Ser Gln Thr Val Pro
      50                  55        



      <210> 2551
      <211> 2176
      <212> PRT
      <213> Homo sapiens


      <400> 2551
 Met Trp Gly Ser Asp Arg Leu Ala Gly Ala Gly Gly Gly Gly Ala Ala
   1               5                  10                  15    
 Val Thr Val Ala Phe Thr Asn Ala Arg Asp Cys Phe Leu His Leu Pro
              20                  25                  30        
 Arg Arg Leu Val Ala Gln Leu His Leu Leu Gln Asn Gln Ala Ile Glu
          35                  40                  45            
 Val Val Trp Ser His Gln Pro Ala Phe Leu Ser Trp Val Glu Gly Arg
      50                  55                  60                
 His Phe Ser Asp Gln Gly Glu Asn Val Ala Glu Ile Asn Arg Gln Val
  65                  70                  75                  80
 Gly Gln Lys Leu Gly Leu Ser Asn Gly Gly Gln Glu Leu His Ala Val
                  85                  90                  95    
 Ser Leu Glu Gln His Leu Leu Asp Gln Ile Arg Ile Val Phe Pro Lys
             100                 105                 110        
 Ala Ile Phe Pro Val Trp Val Asp Gln Gln Thr Tyr Ile Phe Ile Gln
         115                 120                 125            
 Ile Val Ala Leu Ile Pro Ala Ala Ser Tyr Gly Arg Leu Glu Thr Asp
     130                 135                 140                
 Thr Lys Leu Leu Ile Gln Pro Lys Thr Arg Arg Ala Lys Glu Asn Thr
 145                 150                 155                 160
 Phe Ser Lys Ala Asp Ala Glu Tyr Lys Lys Leu His Ser Tyr Gly Arg
                 165                 170                 175    
 Asp Gln Lys Gly Met Met Lys Glu Leu Gln Thr Lys Gln Leu Gln Ser
             180                 185                 190        
 Asn Thr Val Gly Ile Thr Glu Ser Asn Glu Asn Glu Ser Glu Ile Pro
         195                 200                 205            
 Val Asp Ser Ser Ser Val Ala Ser Leu Trp Thr Met Ile Gly Ser Ile
     210                 215                 220                
 Phe Ser Phe Gln Ser Glu Lys Lys Gln Glu Thr Ser Trp Gly Leu Thr
 225                 230                 235                 240
 Glu Ile Asn Ala Phe Lys Asn Met Gln Ser Lys Val Val Pro Leu Asp
                 245                 250                 255    
 Asn Ile Phe Arg Val Cys Lys Ser Gln Pro Pro Ser Ile Tyr Asn Ala
             260                 265                 270        
 Ser Ala Thr Ser Val Phe His Lys His Cys Ala Ile His Val Phe Pro
         275                 280                 285            
 Trp Asp Gln Glu Tyr Phe Asp Val Glu Pro Ser Phe Thr Val Thr Tyr
     290                 295                 300                
 Gly Lys Leu Val Lys Leu Leu Ser Pro Lys Gln Gln Gln Ser Lys Thr
 305                 310                 315                 320
 Lys Gln Asn Val Leu Ser Pro Glu Lys Glu Lys Gln Met Ser Glu Pro
                 325                 330                 335    
 Leu Asp Gln Lys Lys Ile Arg Ser Asp His Asn Glu Glu Asp Glu Lys
             340                 345                 350        
 Ala Cys Val Leu Gln Val Val Trp Asn Gly Leu Glu Glu Leu Asn Asn
         355                 360                 365            
 Ala Ile Lys Tyr Thr Lys Asn Val Glu Val Leu His Leu Gly Lys Val
     370                 375                 380                
 Trp Pro Lys Asp Ile Ser Glu Glu Asp Ile Lys Thr Val Phe Tyr Ser
 385                 390                 395                 400
 Trp Leu Gln Gln Ser Thr Thr Thr Met Leu Pro Leu Val Ile Ser Glu
                 405                 410                 415    
 Glu Glu Phe Ile Lys Leu Glu Thr Lys Asp Gly Pro Ser Arg Ser Tyr
             420                 425                 430        
 Gly Lys Arg Arg Lys Gln Gly Val Asn Ser Leu Gly Val Ser Ser Leu
         435                 440                 445            
 Glu His Ile Thr His Ser Leu Leu Gly Arg Pro Leu Ser Arg Gln Leu
     450                 455                 460                
 Met Ser Leu Val Ala Gly Leu Arg Asn Gly Ala Leu Leu Leu Thr Gly
 465                 470                 475                 480
 Gly Lys Gly Ser Gly Lys Ser Thr Leu Ala Lys Ala Ile Cys Lys Glu
                 485                 490                 495    
 Ala Phe Asp Lys Leu Asp Ala His Val Glu Arg Val Asp Cys Lys Ala
             500                 505                 510        
 Leu Arg Gly Lys Arg Leu Glu Asn Ile Gln Lys Thr Leu Glu Val Ala
         515                 520                 525            
 Phe Ser Glu Ala Val Trp Met Gln Pro Ser Val Val Leu Leu Asp Asp
     530                 535                 540                
 Leu Asp Leu Ile Ala Gly Leu Pro Ala Val Pro Glu His Glu His Ser
 545                 550                 555                 560
 Pro Asp Ala Val Gln Ser Gln Arg Leu Ala His Ala Leu Asn Asp Met
                 565                 570                 575    
 Ile Lys Glu Phe Ile Ser Met Gly Ser Leu Val Ala Leu Ile Ala Thr
             580                 585                 590        
 Ser Gln Ser Gln Gln Ser Leu His Pro Leu Leu Val Ser Ala Gln Gly
         595                 600                 605            
 Val His Ile Phe Gln Cys Val Gln His Ile Gln Pro Pro Asn Gln Glu
     610                 615                 620                
 Gln Arg Cys Glu Ile Leu Cys Asn Val Ile Lys Asn Lys Leu Asp Cys
 625                 630                 635                 640
 Asp Ile Asn Lys Phe Thr Asp Leu Asp Leu Gln His Val Ala Lys Glu
                 645                 650                 655    
 Thr Gly Gly Phe Val Ala Arg Asp Phe Thr Val Leu Val Asp Arg Ala
             660                 665                 670        
 Ile His Ser Arg Leu Ser Arg Gln Ser Ile Ser Thr Arg Glu Lys Leu
         675                 680                 685            
 Val Leu Thr Thr Leu Asp Phe Gln Lys Ala Leu Arg Gly Phe Leu Pro
     690                 695                 700                
 Ala Ser Leu Arg Ser Val Asn Leu His Lys Pro Arg Asp Leu Gly Trp
 705                 710                 715                 720
 Asp Lys Ile Gly Gly Leu His Glu Val Arg Gln Ile Leu Met Asp Thr
                 725                 730                 735    
 Ile Gln Leu Pro Ala Lys Tyr Pro Glu Leu Phe Ala Asn Leu Pro Ile
             740                 745                 750        
 Arg Gln Arg Thr Gly Ile Leu Leu Tyr Gly Pro Pro Gly Thr Gly Lys
         755                 760                 765            
 Thr Leu Leu Ala Gly Val Ile Ala Arg Glu Ser Arg Met Asn Phe Ile
     770                 775                 780                
 Ser Val Lys Gly Pro Glu Leu Leu Ser Lys Tyr Ile Gly Ala Ser Glu
 785                 790                 795                 800
 Gln Ala Val Arg Asp Ile Phe Ile Arg Ala Gln Ala Ala Lys Pro Cys
                 805                 810                 815    
 Ile Leu Phe Phe Asp Glu Phe Glu Ser Ile Ala Pro Arg Arg Gly His
             820                 825                 830        
 Asp Asn Thr Gly Val Thr Asp Arg Val Val Asn Gln Leu Leu Thr Gln
         835                 840                 845            
 Leu Asp Gly Val Glu Gly Leu Gln Gly Val Tyr Val Leu Ala Ala Thr
     850                 855                 860                
 Ser Arg Pro Asp Leu Ile Asp Pro Ala Leu Leu Arg Pro Gly Arg Leu
 865                 870                 875                 880
 Asp Lys Cys Val Tyr Cys Pro Pro Pro Asp Gln Asp Gly Ser Ser Ser
                 885                 890                 895    
 Ser Asp Ser Asp Leu Ser Leu Ser Ser Met Val Phe Leu Asn His Ser
             900                 905                 910        
 Ser Gly Ser Asp Asp Ser Ala Gly Asp Gly Glu Cys Gly Leu Asp Gln
         915                 920                 925            
 Ser Leu Val Ser Leu Glu Met Ser Glu Ile Leu Pro Asp Glu Ser Lys
     930                 935                 940                
 Phe Asn Met Tyr Arg Leu Tyr Phe Gly Ser Ser Tyr Glu Ser Glu Leu
 945                 950                 955                 960
 Gly Asn Gly Thr Ser Ser Asp Leu Glu Asp Glu Ser Met Asn Gln Pro
                 965                 970                 975    
 Gly Pro Ile Lys Thr Arg Leu Ala Ile Ser Gln Ser His Leu Met Thr
             980                 985                 990        
 Ala Leu Gly His Thr Arg Pro Ser Ile Ser Glu Asp Asp Trp Lys Asn
         995                1000                1005            
 Phe Ala Glu Leu Tyr Glu Ser Phe Gln Asn Pro Lys Arg Arg Lys Asn
    1010                1015                1020                
 Gln Ser Gly Thr Met Phe Arg Pro Gly Gln Lys Phe Phe Asp Glu Ile
1025                1030                1035                1040
 Thr Glu Leu Thr Tyr Leu Pro Ser Phe His His Lys Ala Ala Pro His
                1045                1050                1055    
 Gln Ala Glu Pro Gly Pro Asn Ser Ser Ser Ala Ser Ala Pro Pro Pro
            1060                1065                1070        
 Tyr Asn Pro Phe Ile Thr Ser Ser Pro His Thr Gln Ser Gly Leu Gln
        1075                1080                1085            
 Phe Arg Ser Val Thr Ser Pro Pro Pro Ser Ala Gln Gln Phe Pro Leu
    1090                1095                1100                
 Lys Glu Val Ala Gly Ala Lys Gly Ile Val Lys Thr Ala Leu Glu Thr
1105                1110                1115                1120
 Ala Pro Thr Leu Ala Leu Pro Val Ser Ser Gln Pro Phe Ser Leu His
                1125                1130                1135    
 Thr Ala Glu Val Gln Gly Cys Ala Val Gly Ile Leu Thr Gln Gly Pro
            1140                1145                1150        
 Gly Pro Cys Pro Val Ala Phe Leu Ser Lys Gln Leu Asp Leu Thr Val
        1155                1160                1165            
 Leu Gly Ser Pro Ser Cys Leu His Ala Val Ala Ser Ala Ala Leu Ile
    1170                1175                1180                
 Leu Leu Glu Ala Leu Lys Ile Thr Asn Tyr Ala Gln Leu Thr Leu Tyr
1185                1190                1195                1200
 Ser Ser His Asn Phe Gln Asn Leu Phe Ser Phe Ser His Leu Thr His
                1205                1210                1215    
 Ile Leu Ser Ala Pro Arg Leu Leu Gln Leu Tyr Ser Leu Phe Val Glu
            1220                1225                1230        
 Ser Pro Thr Ile Thr Ile Leu Pro Gly Pro Asp Phe Asn Leu Ala Ser
        1235                1240                1245            
 His Ile Ile Leu Asp Thr Thr Pro Asp Pro Asp Asp Cys Met Ser Leu
    1250                1255                1260                
 Ile Tyr Leu Thr Phe Thr Pro Phe Pro His Ile Ser Phe Phe Ser Val
1265                1270                1275                1280
 Pro His Val Asp His Ile Trp Phe Thr Asp Gly Ser Ser Thr Arg Pro
                1285                1290                1295    
 Asp Arg His Ser Pro Ala Lys Ala Gly Tyr Ala Ile Glu Ser Ser Thr
            1300                1305                1310        
 Ser Ile Ile Glu Ala Thr Ala Leu Pro Pro Ser Thr Thr Ser Gln Gln
        1315                1320                1325            
 Ala Glu Leu Ile Ala Leu Thr Arg Ala Phe Thr Leu Ala Lys Gly Leu
    1330                1335                1340                
 His Val Asn Ile Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Leu His
1345                1350                1355                1360
 His His Ala Val Ile Trp Ala Glu Arg Gly Phe Leu Thr Thr Gln Gly
                1365                1370                1375    
 Ser Ser Ile Ile Asn Ala Ser Leu Ile Lys Thr Leu Leu Lys Ala Ala
            1380                1385                1390        
 Leu Leu Pro Lys Glu Ala Gly Val Thr His Cys Lys Gly His Gln Lys
        1395                1400                1405            
 Ala Ser Asp Pro Ile Thr Leu Gly Asn Ala Tyr Ala Asp Lys Gly Val
    1410                1415                1420                
 Arg Cys Ala Pro Asp Pro Ala Arg Arg Pro Leu Pro Leu Pro Ile Gly
1425                1430                1435                1440
 Leu Lys Ala Cys His Cys Ser Cys Thr Ala Lys Ile Gly Gly Lys Tyr
                1445                1450                1455    
 Arg Ala Leu Val Gly Gln Leu Lys Thr Ile Ser Val Ala Thr Gly Leu
            1460                1465                1470        
 Lys Thr Gln Asp Arg Thr Ile Asp Gly Ser Ser Gln Val Ile Glu Glu
        1475                1480                1485            
 Lys Asn His Asn Gly Tyr Ser Val Ile Asp Thr Gly Thr Leu Val Glu
    1490                1495                1500                
 Ala Glu Leu Glu Lys Leu Pro Asn Asn Trp Ser Pro Gln Thr Cys Glu
1505                1510                1515                1520
 Leu Phe Ala Leu Ser Gln Ala Leu Lys Tyr Leu Gln Asn Gln Lys Thr
                1525                1530                1535    
 Ile Ser Ile Leu Ile Gln Lys Glu Pro Ser Pro Ala Leu Gly Leu Thr
            1540                1545                1550        
 Pro Glu Arg Lys Gly Asn Val Gly His Ala Gly Lys Gly Pro Leu Glu
        1555                1560                1565            
 Ser Ser Ser Pro Asp Pro Phe Leu Cys Gly Gln Glu Arg Arg Glu Lys
    1570                1575                1580                
 Gly Cys Arg Thr Ala Thr Ser Val Ser Ile Thr Asn Pro Ile Asn Arg
1585                1590                1595                1600
 Gly Pro Trp Val Val Thr His Pro Gly Lys Glu Leu Thr Pro Glu His
                1605                1610                1615    
 Lys Gly Asn Val Gly His Ala Gly Arg Asp Ile Leu Ala Lys Ala Gly
            1620                1625                1630        
 Ala Ile Ile His Leu Asn Ile Gly Glu Gly Thr Pro Val Cys Cys Pro
        1635                1640                1645            
 Leu Leu Glu Glu Gly Ile Asn Pro Glu Val Trp Ala Thr Glu Gly Gln
    1650                1655                1660                
 Tyr Gly Arg Ala Lys Asn Ala Arg Pro Val Gln Val Lys Leu Lys Asp
1665                1670                1675                1680
 Ser Thr Ser Phe Pro Tyr Gln Arg Gln Tyr Pro Leu Arg Pro Lys Ala
                1685                1690                1695    
 Gln Gln Gly Leu Gln Lys Ile Val Lys Asp Leu Lys Ala Gln Gly Leu
            1700                1705                1710        
 Val Lys Pro Cys Ser Asn Pro Cys Ser Thr Pro Ile Leu Gly Val Gln
        1715                1720                1725            
 Lys Pro Asn Arg Gln Trp Arg Thr Leu Cys His Gln Ala Thr Gln Ala
    1730                1735                1740                
 Leu Phe Asn Phe Leu Ala Thr Cys Gly Tyr Met Val Ser Lys Pro Lys
1745                1750                1755                1760
 Ala Gln Leu Cys Ser Gln Gln Arg Tyr Leu Gly Leu Lys Leu Ser Lys
                1765                1770                1775    
 Gly Thr Arg Ala Leu Ser Glu Glu His Ile Gln Pro Ile Leu Ala Tyr
            1780                1785                1790        
 Pro His Pro Lys Thr Leu Lys Gln Leu Arg Gly Phe Leu Gly Val Ile
        1795                1800                1805            
 Gly Phe Cys Arg Lys Trp Ile Pro Arg Tyr Gly Glu Ile Ala Arg Ser
    1810                1815                1820                
 Leu Asn Thr Leu Ile Lys Glu Thr Gln Lys Ala Asn Thr His Leu Val
1825                1830                1835                1840
 Arg Trp Thr Thr Glu Val Glu Val Ala Phe Gln Ala Leu Thr Gln Ala
                1845                1850                1855    
 Pro Val Leu Ser Leu Pro Thr Gly Gln Asp Phe Ser Ser Tyr Val Thr
            1860                1865                1870        
 Glu Lys Thr Gly Ile Ala Leu Gly Val Leu Thr Gln Ile Arg Gly Met
        1875                1880                1885            
 Ser Leu Gln Pro Val Ala Tyr Leu Thr Lys Glu Ile Asp Val Val Ala
    1890                1895                1900                
 Lys Gly Trp Pro His Cys Leu Arg Val Val Ala Ala Val Val Val Leu
1905                1910                1915                1920
 Val Ser Glu Ala Val Lys Leu Ile Gln Gly Arg Asp Leu Thr Val Trp
                1925                1930                1935    
 Thr Ser His Asp Val Asn Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp
            1940                1945                1950        
 Leu Ser Asp Asn His Leu Leu Lys Tyr Gln Ala Leu Leu Leu Glu Gly
        1955                1960                1965            
 Pro Val Leu Arg Leu Cys Thr Cys Ala Thr Leu Asn Pro Ala Thr Phe
    1970                1975                1980                
 Leu Pro Asp Asn Lys Glu Lys Ile Glu His Asn Cys Gln Gln Val Ile
1985                1990                1995                2000
 Val Gln Thr Tyr Ala Ala Gln Gly Asp Pro Leu Glu Val Pro Leu Thr
                2005                2010                2015    
 Asp Pro Asp Leu Thr Leu Cys Thr Asp Gly Ser Ser Phe Val Glu Lys
            2020                2025                2030        
 Gly Leu Arg Lys Val Gly Tyr Ala Val Val Ser Asp Asn Gly Ile Leu
        2035                2040                2045            
 Glu Ser Asn Pro Leu Thr Pro Gly Thr Ser Ala Gln Leu Ala Glu Leu
    2050                2055                2060                
 Ile Ala Leu Thr Trp Ala Leu Glu Leu Gly Glu Glu Lys Arg Ala Asn
2065                2070                2075                2080
 Ile Tyr Thr Asp Ser Lys Tyr Ala Tyr Leu Val Leu His Ala His Ala
                2085                2090                2095    
 Ala Ile Trp Lys Glu Arg Glu Phe Leu Thr Ser Glu Arg Thr Pro Ile
            2100                2105                2110        
 Lys His Gln Glu Ala Ile Arg Lys Leu Leu Leu Ala Val Gln Lys Pro
        2115                2120                2125            
 Lys Glu Val Ala Val Leu His Cys Arg Gly His Gln Lys Gly Lys Glu
    2130                2135                2140                
 Arg Glu Ile Glu Glu Asn Cys Gln Ala Asp Ile Glu Ala Lys Arg Ala
2145                2150                2155                2160
 Ala Arg Gln Asp Pro Pro Leu Glu Met Leu Ile Lys Gln Pro Leu Val
                2165                2170                2175    





      <210> 2552
      <211> 108
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(108)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2552
 Ile Leu Pro Thr Ser Leu Phe Phe Leu Phe Cys Phe Val Phe Phe Val
   1               5                  10                  15    
 Cys Phe Xaa Asp Arg Val Leu Leu Leu Ser Pro Gly Trp Ser Ala Val
              20                  25                  30        
 Ala Arg Ser Trp Leu Tyr Cys Asn Leu Ser Leu Arg Gly Phe Lys Gly
          35                  40                  45            
 Phe Ser Cys Leu Ser Leu Leu Ser Asn Trp Asp Tyr Arg Cys Thr Pro
      50                  55                  60                
 Leu Arg Ser Ala Asn Phe Val Phe Leu Cys Arg Asp Arg Val Ser Pro
  65                  70                  75                  80
 Cys Trp Pro Thr Ser Val Ser Asn Ser Xaa Pro Gln Val Ile His Pro
                  85                  90                  95    
 Pro Trp Pro Pro Lys Val Leu Gly Ile Thr Arg Val
             100                 105            



      <210> 2553
      <211> 246
      <212> PRT
      <213> Homo sapiens


      <400> 2553
 Met Arg Pro Val Asp Pro Asp Gly Thr Glu His Ser Leu Phe Cys Pro
   1               5                  10                  15    
 Leu Thr Ala Leu Arg Gly Met Val Asn Ser Arg Ile Gln Lys Ser Pro
              20                  25                  30        
 Gly Lys Pro Ser Val Cys Asp Val Pro Leu Pro Ile Ser Pro Gly Gln
          35                  40                  45            
 Ser Ser Gln Leu His Gly Lys Val Phe Gly Gln Leu Asn Ala Gly Lys
      50                  55                  60                
 Ala Ala Glu Phe Leu Lys Ser Pro Pro Asp His Gln Ala Gln Ala Ala
  65                  70                  75                  80
 Ser Thr Ser Gly Pro Gln Lys Thr Thr Leu Ser Lys Arg Gly Leu Arg
                  85                  90                  95    
 Leu Gln Pro Cys Gln Leu His Ser Ala Pro His Ser Phe Gln Leu Leu
             100                 105                 110        
 Pro Leu Thr Gln Lys Ser Thr Trp Asp Leu Arg Gly Ser Ala Pro Leu
         115                 120                 125            
 His Ala Ala Gln Thr Ser Leu Ser Glu Phe Ser Cys His Arg Pro Asp
     130                 135                 140                
 Val Glu Asp Thr Leu Gly Thr Lys Gly Pro Asp Lys Thr Gln Cys Gln
 145                 150                 155                 160
 Ser Glu Asn Ser Thr Arg Pro Gln Tyr Ser Pro Glu Thr Ser Gln Asn
                 165                 170                 175    
 Gln Pro Val Gly Lys Gly Thr Asp Leu Lys Val Thr Lys Leu Gly Val
             180                 185                 190        
 Pro Ser Leu Met Ala Gln Asp Gly Val Asn Tyr Ser Val Lys Thr Glu
         195                 200                 205            
 Ala His Ser Thr Gly Thr Thr Ala Glu Pro Leu Ser Ser Gln Asp Arg
     210                 215                 220                
 Ala Val Arg Gly His Asn Thr Asp Ser His Val Gln Thr Pro Asp Leu
 225                 230                 235                 240
 Gly Glu Asp Thr Ala Leu
                 245    



      <210> 2554
      <211> 292
      <212> PRT
      <213> Homo sapiens


      <400> 2554
 Lys Ala Thr Arg Phe Ile Ser Ala Ala Phe Val Val Leu Asn Lys Gln
   1               5                  10                  15    
 Gly Val Ser Pro Ala Lys Leu Pro His Thr Ser Trp Ser Trp Ser Leu
              20                  25                  30        
 Gln Thr Leu Ser Phe Leu Phe Ser Gly Asp Leu Ala Glu Lys Ser Leu
          35                  40                  45            
 Gln Cys Phe Pro Cys Ser Ala Met Leu Leu Glu Leu Ile Pro Leu Leu
      50                  55                  60                
 Gly Ile His Phe Val Leu Arg Thr Ala Arg Ala Gln Ser Val Thr Gln
  65                  70                  75                  80
 Pro Asp Ile His Ile Thr Val Ser Glu Gly Ala Ser Leu Glu Leu Arg
                  85                  90                  95    
 Cys Asn Tyr Ser Tyr Gly Ala Thr Pro Tyr Leu Phe Trp Met Glu Arg
             100                 105                 110        
 Thr Val Glu Glu Ala Phe Ile Leu Leu Val Cys Leu Lys Pro Trp Arg
         115                 120                 125            
 Val Ala Ser Ser Leu Glu Lys Lys Glu Lys Glu Asp Glu Ser Phe Gln
     130                 135                 140                
 Leu Leu Leu Gly Ser Arg Tyr Asn Val Leu Lys Gly Ser Arg Gly Glu
 145                 150                 155                 160
 Thr Ser Glu Gly Gly Ala Glu Ser Phe Ser Ser Gln Ser Pro Gly Glu
                 165                 170                 175    
 Asn Gln Leu Tyr Ser Glu Met Gln Phe Phe Tyr Leu Cys Glu Gln Arg
             180                 185                 190        
 Ala Val Val Pro Thr Glu Ser Trp Val Gly Leu Ile Asn Leu Phe Phe
         195                 200                 205            
 Met Ala Ser Trp Met Lys His Ser Gly Lys Leu Trp Ser Lys Arg Asn
     210                 215                 220                
 Ser Glu Glu Leu Cys Gly Thr Leu His Ile Thr Ala Ala Gln Leu Lys
 225                 230                 235                 240
 Asp Ser Gly Thr Tyr Phe Cys Ala Val Glu Ala Gln Phe Ser Gln Glu
                 245                 250                 255    
 Ile Cys Ser Leu Asp Pro Asn Cys Ser Trp Ala Cys Ser Pro Asn Pro
             260                 265                 270        
 Phe Arg Glu Arg Gly Met Leu Pro Pro Gln Tyr His Leu His Ser Phe
         275                 280                 285            
 Gly Phe Ser Asp
     290        



      <210> 2555
      <211> 171
      <212> PRT
      <213> Homo sapiens


      <400> 2555
 Glu Thr Ser Leu Glu Arg Glu Arg Leu Ser Phe Cys Thr Gly Ser Arg
   1               5                  10                  15    
 Thr Thr Arg Ser Ala Glu Leu Lys Ala Val Gly Phe Glu Ala Ala Leu
              20                  25                  30        
 Gln Glu Val Ile Thr Pro Glu Val Val Pro Ala Ser Gln Ser Glu Ala
          35                  40                  45            
 Tyr Gln Thr Leu Arg Gln Asn Gln Ala Gln Val His Asn Phe Phe Phe
      50                  55                  60                
 Phe Trp Gly Gly Asp Ser Pro Thr Leu Ser Pro Arg Leu Glu Cys Ser
  65                  70                  75                  80
 Ser Ala Ile Ser Ala His Cys Asn Leu Arg Leu Pro Gly Ser Ser Asn
                  85                  90                  95    
 Ser Pro Thr Ser Ala Ser Arg Val Ala Gly Thr Thr Gly Ala Cys Arg
             100                 105                 110        
 His Ala Arg Leu Ile Phe Cys Ile Leu Val Glu Met Gly Phe His Arg
         115                 120                 125            
 Val Ala Gln Ala Gly Arg Glu Leu Leu Ser Ser Ala Asn Pro Pro Thr
     130                 135                 140                
 Ser Ala Ser Gln Ser Ala Gly Ile Thr Gly Met Ser His His Ala Gln
 145                 150                 155                 160
 Pro Ser Ser Gln Leu Leu Ile Ser Ser Cys Cys
                 165                 170    



      <210> 2556
      <211> 142
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(142)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2556
 Tyr Arg Glu Val Met Val Ser Glu Ser Xaa Glu Thr Pro Ala Gly Ala
   1               5                  10                  15    
 Arg Gly Arg Pro Tyr Tyr Phe Ser Ala Pro Gly Thr Ala Pro Pro Ala
              20                  25                  30        
 Ile Asn Val His Pro Pro Pro Pro Ser Leu Ser Ala Thr Pro His Pro
          35                  40                  45            
 Pro Gln Pro Gln Pro Pro Pro Pro His Gln His Asn Ala Lys Ala Arg
      50                  55                  60                
 Val Ala Thr Ile Arg Thr Lys Arg Thr Ser Asn Cys Arg Ile Arg Ser
  65                  70                  75                  80
 Arg Lys Val Arg Lys Ser Pro Pro Glu Lys Trp Val Gly Phe Asn Arg
                  85                  90                  95    
 Arg Pro Lys Ala Ser Cys Pro Ser Pro Pro Gly Ala Ala Arg Val Asp
             100                 105                 110        
 Val Gly Gly Glu Thr Glu Arg Arg Glu Gln Ala Ala Ala Pro Gly Glu
         115                 120                 125            
 Met Gly Lys Trp Ala Arg Pro Gly Glu Glu Tyr Phe His Ser
     130                 135                 140        



      <210> 2557
      <211> 195
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(195)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2557
 Ala Ala Ala Ala Pro Ala Gly Gly Asn Pro Glu Gln Arg Leu Asp Tyr
   1               5                  10                  15    
 Glu Arg Ala Ala Ala Leu Gly Gly Pro Asp Gly Arg Ala Trp Gly Gly
              20                  25                  30        
 Arg Ser Pro Leu Pro Pro Pro Ala Pro Xaa Ala Gln Gly Ala Pro Gly
          35                  40                  45            
 Pro Arg Trp Pro Pro Pro Arg Ala Gly Ser Pro Ala Pro Ser Pro Ala
      50                  55                  60                
 Gly Cys Gly Gly Gly Lys Gly Gly Gly Leu Val Thr Pro Gly Arg Gly
  65                  70                  75                  80
 Gly Pro Arg Ala Ala Gly Arg Glu Leu Arg Ala Val Arg Cys Pro Cys
                  85                  90                  95    
 Pro Val Arg Pro Arg Pro Pro Ser Lys Pro Ala Leu Gly Gly Ser Leu
             100                 105                 110        
 Pro Gln Pro Glu Pro Ala Ala Ala Pro Gly Pro Ser Ile Arg Pro Val
         115                 120                 125            
 Leu Pro Ile Gln Thr Gly Ser Pro Trp Arg Arg Pro Lys Ser Leu Arg
     130                 135                 140                
 Pro Val Leu Gly Thr Arg Val Gly Arg Thr Pro Pro Leu Pro Pro Pro
 145                 150                 155                 160
 Pro Asp Pro Ala Gly Pro Pro Pro Leu Pro Leu Pro Gly Pro His Pro
                 165                 170                 175    
 Ser Arg Pro Pro Pro Pro Thr Gly Pro Trp Arg Pro Ala Arg Ala Asp
             180                 185                 190        
 Gly Arg Val
         195



      <210> 2558
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 2558
 Pro Arg Val Arg Val Gln Trp Ala Gln Leu Ser Gln Asp Lys Lys Gly
   1               5                  10                  15    
 Glu Met Asn Ser Met Thr Ser Thr Ala Gly Pro Pro Gly Ser Ser Ser
              20                  25                  30        
 Ala Pro Cys Ala Thr Arg Arg Asn Leu Leu Gln Arg Gln His Leu Gln
          35                  40                  45            
 Arg Leu Ser Gly Glu Phe Lys Lys Asp Pro Ala Thr Tyr Ser Lys His
      50                  55                  60                
 Leu Glu Pro Leu Glu Glu Glu Arg Asp Lys
  65                  70                



      <210> 2559
      <211> 75
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(75)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2559
 Gly Arg Leu Trp Ser Ala Met Thr Pro Gly Lys Leu Lys Thr Leu Cys
   1               5                  10                  15    
 Lys Ile Asp Trp Pro Ala Leu Glu Val Gly Trp Pro Leu Glu Gly Ser
              20                  25                  30        
 Leu Asp Arg Ser Leu Val Ser Lys Val Trp His Lys Val Thr Tyr Lys
          35                  40                  45            
 Pro Arg Asn Pro Asp Gln Phe Pro Tyr Arg Asp Thr Xaa Leu Glu Leu
      50                  55                  60                
 Val Leu Asp Pro Pro Pro Pro Thr His Ser Gly
  65                  70                  75



      <210> 2560
      <211> 153
      <212> PRT
      <213> Homo sapiens


      <400> 2560
 Asp Asn His Pro Ser Phe Pro Arg Leu Pro Ser Ser Arg Pro Gly Thr
   1               5                  10                  15    
 Lys Glu Val Leu Lys Glu Ile His Ile Ser Asp Thr Thr Ala Asp Val
              20                  25                  30        
 Ile Phe Tyr Pro Ile Tyr Arg Met Ser Glu Met Ile Phe Arg Arg Ile
          35                  40                  45            
 Lys Met Pro Trp Leu Trp Leu Asp Leu Trp Tyr Leu Met Phe Lys Glu
      50                  55                  60                
 Gly Trp Glu His Lys Lys Ser Leu Lys Ile Leu His Thr Phe Thr Asn
  65                  70                  75                  80
 Ser Val Ile Ala Glu Arg Ala Asn Glu Met Asn Ala Asn Glu Asp Cys
                  85                  90                  95    
 Arg Gly Asp Gly Arg Gly Ser Ala Pro Ser Lys Asn Lys Arg Arg Ala
             100                 105                 110        
 Phe Leu Asp Leu Leu Leu Ser Val Thr Asp Asp Glu Gly Asn Arg Leu
         115                 120                 125            
 Ser His Glu Asp Ile Arg Glu Glu Val Asp Thr Phe Met Phe Glu Val
     130                 135                 140                
 Leu Tyr Ile Val Arg Phe Arg Tyr His
 145                 150            



      <210> 2561
      <211> 247
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(247)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2561
 Ser Leu His Leu Ser Glu Arg Ala Asp Trp Gln Tyr Ser Gln Arg Ala
   1               5                  10                  15    
 Gly Asp Ala Val Glu Val Phe Phe Ser Arg Thr Ala Arg Asp Asn Arg
              20                  25                  30        
 Leu Gly Cys Met Phe Val Arg Cys Ala Pro Ser Ser Arg Tyr Thr Leu
          35                  40                  45            
 Leu Phe Ser His Gly Asn Ala Val Asp Leu Gly Gln Met Cys Ser Phe
      50                  55                  60                
 Tyr Ile Gly Leu Gly Ser Arg Ile Asn Cys Asn Ile Phe Ser Tyr Asp
  65                  70                  75                  80
 Tyr Ser Gly Tyr Gly Val Ser Ser Gly Lys Pro Ser Glu Lys Asn Leu
                  85                  90                  95    
 Tyr Ala Asp Ile Asp Ala Ala Trp Gln Ala Leu Arg Thr Arg Tyr Gly
             100                 105                 110        
 Val Ser Pro Glu Asn Ile Ile Leu Tyr Gly Gln Ser Ile Gly Thr Val
         115                 120                 125            
 Pro Thr Val Asp Leu Ala Ser Arg Tyr Glu Cys Ala Ala Val Ile Leu
     130                 135                 140                
 His Ser Pro Leu Met Ser Gly Leu Arg Val Ala Phe Pro Asp Thr Arg
 145                 150                 155                 160
 Lys Thr Tyr Cys Phe Asp Ala Phe Pro Ser Ile Asp Lys Ile Ser Lys
                 165                 170                 175    
 Val Thr Ser Pro Val Leu Val Ile His Gly Thr Glu Asp Glu Val Ile
             180                 185                 190        
 Asp Phe Ser His Gly Leu Ala Met Tyr Glu Arg Cys Pro Arg Ala Val
         195                 200                 205            
 Glu Pro Leu Trp Val Glu Gly Ala Gly His Asn Asp Ile Glu Leu Tyr
     210                 215                 220                
 Ala Gln Tyr Leu Glu Arg Leu Lys Gln Phe Ile Ser His Glu Leu Pro
 225                 230                 235                 240
 Asn Ser Xaa Arg Gln Ser Lys
                 245        



      <210> 2562
      <211> 227
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(227)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2562
 Ala Ala Ala Ser Ala Phe Lys Pro Gly Leu Ala Leu Ser Asp Arg Ala
   1               5                  10                  15    
 Phe Ala Ala Trp Glu Pro Ser Gly Ala Ala Val Ser Arg Ser Pro Leu
              20                  25                  30        
 Ser Pro Pro Ser Arg Pro Phe Ala Ser Arg Glu Pro Ala Gly Phe Arg
          35                  40                  45            
 Ala Ala Leu Ala Asp Pro Pro Gly Met Pro Arg Tyr Glu Leu Ala Leu
      50                  55                  60                
 Ile Leu Lys Ala Met Gln Arg Pro Glu Thr Ala Ala Thr Leu Lys Arg
  65                  70                  75                  80
 Thr Ile Glu Ala Leu Met Asp Arg Gly Ala Ile Val Arg Asp Leu Glu
                  85                  90                  95    
 Asn Leu Gly Glu Arg Ala Leu Pro Tyr Arg Ile Ser Ala His Ser Gln
             100                 105                 110        
 Gln His Asn Arg Gly Gly Tyr Phe Leu Val Asp Phe Tyr Ala Pro Thr
         115                 120                 125            
 Ala Ala Val Glu Ser Met Val Glu His Leu Ser Arg Asp Ile Asp Val
     130                 135                 140                
 Ile Arg Gly Asn Ile Val Lys His Pro Leu Thr Gln Glu Leu Lys Glu
 145                 150                 155                 160
 Trp Glu Gly Ile Val Pro Val Pro Leu Ala Glu Lys Leu Tyr Ser Thr
                 165                 170                 175    
 Lys Lys Arg Lys Lys Xaa Glu Asp Ser Pro Asp Phe Ser Leu Ile Cys
             180                 185                 190        
 Asn Ser Phe Thr Phe Gly Gln His Gly Arg Glu Gly Arg Ile Cys Lys
         195                 200                 205            
 Phe Gly Leu Tyr Ile Ser Met Cys Cys Arg Cys Cys Leu Ile Phe Leu
     210                 215                 220                
 Arg Tyr Phe
 225        



      <210> 2563
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 2563
 Met Asp Lys Ser Leu Leu Leu Glu Leu Pro Ile Leu Leu Cys Cys Phe
   1               5                  10                  15    
 Arg Ala Leu Ser Gly Ser Leu Ser Met Arg Asn Asp Ala Val Ile Glu
              20                  25                  30        
 Ile Val Gln Cys Arg Met Cys His Leu Gln Phe Pro Gly Glu Lys Cys
          35                  40                  45            
 Ser Arg Gly Arg Gly Ile Cys Thr Ala Thr Thr Glu Glu Ala Cys Met
      50                  55                  60                
 Val Gly Arg Met Phe Lys Arg Asp Gly Asn Pro Trp Leu Thr Phe Met
  65                  70                  75                  80
 Gly Cys Leu Lys Asn Cys Ala Asp Val Lys Gly Ile Arg Trp Ser Val
                  85                  90                  95    
 Tyr Leu Val Asn Phe Arg Cys Cys Arg Ser His Asp Leu Cys Asn Glu
             100                 105                 110        
 Asp Leu
        



      <210> 2564
      <211> 45
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(45)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2564
 Leu Gln Arg Leu Glu Cys Ser Gly Thr Ile Ser Ala His Cys Asn Leu
   1               5                  10                  15    
 Cys Leu Leu Gly Ser Ser Asn Pro Leu Ala Ser Ala Ser Xaa Ile Ala
              20                  25                  30        
 Gly Thr Thr Gly Thr Leu Thr Gly Asp Val Asp Ser Thr
          35                  40                  45



      <210> 2565
      <211> 36
      <212> PRT
      <213> Homo sapiens


      <400> 2565
 Glu Ile Ser Asn Ile Gln Gln Ala Asp Phe Pro Gly Val Leu Ala Thr
   1               5                  10                  15    
 His Pro Ala Phe Ser Arg Leu Leu Pro Cys Leu His Phe Ile Pro Lys
              20                  25                  30        
 Ser Ala Asn Gln
          35    



      <210> 2566
      <211> 236
      <212> PRT
      <213> Homo sapiens


      <400> 2566
 Pro Ala Pro Val Lys Asp Glu Gly Pro Met Val Ser Ala Ser Val Lys
   1               5                  10                  15    
 Asp Gln Gly Pro Met Val Ser Ala Pro Val Lys Asp Gln Gly Pro Ile
              20                  25                  30        
 Val Pro Ala Pro Val Lys Gly Glu Gly Pro Ile Val Pro Ala Pro Val
          35                  40                  45            
 Lys Asp Glu Gly Pro Met Val Ser Ala Pro Ile Lys Asp Gln Asp Pro
      50                  55                  60                
 Met Val Pro Glu His Pro Lys Asp Glu Ser Ala Met Ala Thr Ala Pro
  65                  70                  75                  80
 Ile Lys Asn Gln Gly Ser Met Val Ser Glu Pro Val Lys Asn Gln Gly
                  85                  90                  95    
 Leu Val Val Ser Gly Pro Val Lys Asp Gln Asp Val Val Val Pro Glu
             100                 105                 110        
 His Ala Lys Val His Asp Ser Ala Val Val Ala Pro Val Lys Asn Gln
         115                 120                 125            
 Gly Pro Val Val Pro Glu Ser Val Lys Asn Gln Asp Pro Ile Leu Pro
     130                 135                 140                
 Val Leu Val Lys Asp Gln Gly Pro Thr Val Leu Gln Pro Pro Lys Asn
 145                 150                 155                 160
 Gln Gly Arg Ile Val Pro Glu Pro Leu Lys Asn Gln Val Pro Ile Val
                 165                 170                 175    
 Pro Val Pro Leu Lys Asp Gln Asp Pro Leu Val Pro Val Pro Ala Lys
             180                 185                 190        
 Asp Gln Gly Pro Ala Val Pro Glu Pro Leu Lys Thr Gln Gly Pro Arg
         195                 200                 205            
 Asp Pro Gln Leu Pro Thr Val Ser Pro Leu Pro Arg Val Met Ile Pro
     210                 215                 220                
 Thr Ala Pro His Thr Glu Tyr Ile Glu Ser Ser Pro
 225                 230                 235    



      <210> 2567
      <211> 118
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(118)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2567
 Gln Gln Gly Lys Asn Gln Glu Cys Ile Arg Asn Gln His Thr Arg Ala
   1               5                  10                  15    
 Pro Gly Arg Gly Ala Ser Pro Gln Gln Gly Glu Gly Lys Thr Trp Ala
              20                  25                  30        
 Trp Val Gly His Pro Val Pro His Ala Leu Val Ile Pro Gly Leu Gln
          35                  40                  45            
 Arg Gly Ser Ala Arg Gly Leu Ala Trp Arg Gln Leu Gly Arg Ala Arg
      50                  55                  60                
 Xaa Pro Arg Pro Pro Ala Pro Pro Arg Ala Cys Arg Pro Glu Glu Pro
  65                  70                  75                  80
 Pro Tyr Thr Pro Gly Arg Arg Ala Pro Gly Arg Pro Ala Pro Ala Pro
                  85                  90                  95    
 Arg Ser Ala Cys Gly Trp Ala Ala Ser Ala Ser Arg Trp Cys Arg Arg
             100                 105                 110        
 Thr Val Phe Phe Ser Gln
         115            



      <210> 2568
      <211> 305
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(305)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2568
 Glu Glu Leu Leu Cys Leu Asp Val Ser Glu Asn Arg Leu Glu Arg Leu
   1               5                  10                  15    
 Pro Glu Glu Ile Ser Gly Leu Thr Ser Leu Thr Asp Leu Val Ile Ser
              20                  25                  30        
 Gln Asn Leu Leu Glu Thr Ile Pro Asp Gly Ile Gly Lys Leu Lys Lys
          35                  40                  45            
 Leu Ser Ile Leu Lys Val Asp Gln Asn Arg Leu Thr Gln Leu Pro Glu
      50                  55                  60                
 Ala Val Gly Glu Cys Glu Ser Leu Thr Glu Leu Val Leu Thr Glu Asn
  65                  70                  75                  80
 Gln Leu Leu Thr Leu Pro Xaa Ser Ile Gly Lys Leu Lys Lys Leu Ser
                  85                  90                  95    
 Asn Leu Asn Ala Asp Arg Asn Lys Leu Val Ser Leu Pro Lys Glu Ile
             100                 105                 110        
 Gly Gly Cys Cys Ser Leu Thr Val Phe Cys Val Arg Asp Asn Arg Leu
         115                 120                 125            
 Thr Arg Ile Pro Ala Glu Val Ser Gln Ala Thr Glu Leu His Val Leu
     130                 135                 140                
 Asp Val Ala Gly Asn Arg Leu Leu His Leu Pro Leu Ser Leu Thr Ala
 145                 150                 155                 160
 Leu Lys Leu Lys Ala Leu Trp Leu Ser Asp Asn Gln Ser Gln Pro Leu
                 165                 170                 175    
 Leu Thr Phe Gln Thr Asp Thr Asp Tyr Thr Thr Gly Glu Lys Ile Leu
             180                 185                 190        
 Thr Cys Val Leu Leu Pro Gln Leu Pro Ser Glu Pro Thr Cys Gln Glu
         195                 200                 205            
 Asn Leu Pro Arg Cys Gly Ala Leu Glu Asn Leu Val Asn Asp Val Ser
     210                 215                 220                
 Asp Glu Ala Trp Asn Glu Arg Ala Val Asn Arg Val Ser Ala Ile Arg
 225                 230                 235                 240
 Phe Val Glu Asp Glu Lys Asp Glu Glu Asp Asn Glu Thr Arg Thr Leu
                 245                 250                 255    
 Leu Arg Arg Ala Thr Pro His Pro Gly Glu Leu Lys His Met Lys Lys
             260                 265                 270        
 Thr Val Glu Asn Leu Arg Asn Asp Met Asn Ala Ala Lys Gly Leu Asp
         275                 280                 285            
 Ser Asn Lys Asn Glu Val Asn His Ala Ile Asp Arg Val Thr Thr Ser
     290                 295                 300                
 Val
 305



      <210> 2569
      <211> 297
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(297)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2569
 Thr Ser Lys Gln Asn Ala Ala Pro Leu Val Lys Tyr Phe Gln Glu Lys
   1               5                  10                  15    
 Gly Leu Ile Met Thr Phe Asp Ala Asp Arg Asp Glu Asp Glu Val Phe
              20                  25                  30        
 Tyr Asp Ile Ser Met Ala Val Asp Asn Lys Leu Phe Pro Asn Lys Glu
          35                  40                  45            
 Ala Ala Ala Gly Ser Ser Asp Leu Asp Pro Ser Met Ile Leu Asp Thr
      50                  55                  60                
 Gly Glu Ile Ile Asp Thr Gly Ser Asp Tyr Glu Asp Gln Gly Asp Asp
  65                  70                  75                  80
 Gln Leu Asn Val Phe Gly Glu Asp Thr Met Gly Gly Phe Met Glu Asp
                  85                  90                  95    
 Leu Arg Lys Cys Lys Ile Ile Phe Ile Ile Gly Gly Pro Gly Ser Gly
             100                 105                 110        
 Lys Gly Thr Gln Cys Glu Lys Leu Val Glu Lys Tyr Gly Phe Thr His
         115                 120                 125            
 Leu Ser Thr Gly Glu Leu Leu Arg Glu Glu Leu Ala Ser Xaa Ser Glu
     130                 135                 140                
 Arg Ser Lys Leu Ile Lys Asp Ile Met Glu Arg Gly Asp Leu Val Pro
 145                 150                 155                 160
 Ser Gly Ile Val Leu Glu Leu Leu Lys Glu Ala Met Val Gly Ser Leu
                 165                 170                 175    
 Gly Asp Thr Arg Gly Phe Leu Ile Asp Gly Tyr Pro Arg Glu Val Lys
             180                 185                 190        
 Gln Gly Glu Glu Phe Gly Arg Arg Ile Trp Arg Pro His Ser Trp Val
         195                 200                 205            
 Ile Cys Met Glu Cys Ser Ala Asp Thr Met Thr Asn Arg Leu Leu Gln
     210                 215                 220                
 Arg Ser Arg Ser Ser Leu Pro Val Asp Asp Thr Thr Lys Thr Met Ala
 225                 230                 235                 240
 Lys Arg Leu Glu Ala Tyr Tyr Arg Ala Ser Ile Pro Val Ile Ala Tyr
                 245                 250                 255    
 Tyr Glu Thr Lys Thr Gln Leu His Lys Ile Asn Ala Glu Gly Thr Pro
             260                 265                 270        
 Glu Asp Val Phe Leu Gln Leu Cys Thr Ser Xaa Leu Thr Leu Leu Phe
         275                 280                 285            
 Ser Glu Gly Lys Asn Ala Cys Leu Gly
     290                 295        



      <210> 2570
      <211> 887
      <212> PRT
      <213> Homo sapiens


      <400> 2570
 Gly Ala Tyr His Lys His Leu Met Glu Leu Ala Leu Gln Gln Thr Tyr
   1               5                  10                  15    
 Gln Asp Thr Cys Asn Cys Ile Lys Ser Arg Ile Lys Leu Glu Phe Glu
              20                  25                  30        
 Lys Arg Gln Gln Glu Arg Leu Leu Leu Ser Leu Leu Pro Ala His Ile
          35                  40                  45            
 Ala Met Glu Met Lys Ala Glu Ile Ile Gln Arg Leu Gln Gly Pro Lys
      50                  55                  60                
 Ala Gly Gln Met Glu Asn Thr Asn Asn Phe His Asn Leu Tyr Val Lys
  65                  70                  75                  80
 Arg His Thr Asn Val Ser Ile Leu Tyr Ala Asp Ile Val Gly Phe Thr
                  85                  90                  95    
 Arg Leu Ala Ser Asp Cys Ser Pro Gly Glu Leu Val His Met Leu Asn
             100                 105                 110        
 Glu Leu Phe Gly Lys Phe Asp Gln Ile Ala Lys Glu Asn Glu Cys Met
         115                 120                 125            
 Arg Ile Lys Ile Leu Gly Asp Cys Tyr Tyr Cys Val Ser Gly Leu Pro
     130                 135                 140                
 Ile Ser Leu Pro Asn His Ala Lys Asn Cys Val Lys Met Gly Leu Asp
 145                 150                 155                 160
 Met Cys Glu Ala Ile Lys Lys Val Arg Asp Ala Thr Gly Val Asp Ile
                 165                 170                 175    
 Asn Met Arg Val Gly Val His Ser Gly Asn Val Leu Cys Gly Val Ile
             180                 185                 190        
 Gly Leu Gln Lys Trp Gln Tyr Asp Val Trp Ser His Asp Val Thr Leu
         195                 200                 205            
 Ala Asn His Met Glu Ala Gly Gly Val Pro Gly Arg Val His Ile Ser
     210                 215                 220                
 Ser Val Thr Leu Glu His Leu Asn Gly Ala Tyr Lys Val Glu Glu Gly
 225                 230                 235                 240
 Asp Gly Asp Ile Arg Asp Pro Tyr Leu Lys Gln His Leu Val Lys Thr
                 245                 250                 255    
 Tyr Phe Val Ile Asn Pro Lys Gly Glu Arg Arg Ser Pro Gln His Leu
             260                 265                 270        
 Phe Arg Pro Arg His Thr Leu Asp Gly Ala Lys Met Arg Ala Ser Val
         275                 280                 285            
 Arg Met Thr Arg Tyr Leu Glu Ser Trp Gly Ala Ala Lys Pro Phe Ala
     290                 295                 300                
 His Leu His His Arg Asp Ser Met Thr Thr Glu Asn Gly Lys Ile Ser
 305                 310                 315                 320
 Thr Thr Asp Val Pro Met Gly Gln His Asn Phe Gln Asn Arg Thr Leu
                 325                 330                 335    
 Arg Thr Lys Ser Gln Lys Lys Arg Phe Glu Glu Glu Leu Asn Glu Arg
             340                 345                 350        
 Met Ile Gln Ala Ile Asp Gly Ile Asn Ala Gln Lys Gln Trp Leu Lys
         355                 360                 365            
 Ser Glu Asp Ile Gln Arg Ile Ser Leu Leu Phe Tyr Asn Lys Val Leu
     370                 375                 380                
 Glu Lys Glu Tyr Arg Ala Thr Ala Leu Pro Ala Phe Lys Tyr Tyr Val
 385                 390                 395                 400
 Thr Cys Ala Cys Leu Ile Phe Phe Cys Ile Phe Ile Val Gln Ile Leu
                 405                 410                 415    
 Val Leu Pro Lys Thr Ser Val Leu Gly Ile Ser Phe Gly Ala Ala Phe
             420                 425                 430        
 Leu Leu Leu Ala Phe Ile Leu Phe Val Cys Phe Ala Gly Gln Leu Leu
         435                 440                 445            
 Gln Cys Ser Lys Lys Ala Ser Pro Leu Leu Met Trp Leu Leu Lys Ser
     450                 455                 460                
 Ser Gly Ile Ile Ala Asn Arg Pro Trp Pro Arg Ile Ser Leu Thr Ile
 465                 470                 475                 480
 Ile Thr Thr Ala Ile Ile Leu Met Met Ala Val Phe Asn Met Phe Phe
                 485                 490                 495    
 Leu Ser Asp Ser Glu Glu Thr Ile Pro Pro Thr Ala Asn Thr Thr Asn
             500                 505                 510        
 Thr Ser Phe Ser Ala Ser Asn Asn Gln Val Ala Ile Leu Arg Ala Gln
         515                 520                 525            
 Ile Leu Phe Phe Leu Pro Tyr Phe Ile Tyr Ser Cys Ile Leu Gly Leu
     530                 535                 540                
 Ile Ser Cys Ser Val Phe Leu Arg Val Asn Tyr Glu Leu Lys Met Leu
 545                 550                 555                 560
 Ile Met Met Val Ala Leu Val Gly Tyr Asn Thr Ile Leu Leu His Thr
                 565                 570                 575    
 His Ala His Val Leu Gly Asp Tyr Ser Gln Val Leu Phe Glu Arg Pro
             580                 585                 590        
 Gly Ile Trp Lys Asp Leu Lys Thr Met Gly Ser Val Ser Leu Ser Ile
         595                 600                 605            
 Phe Phe Ile Thr Leu Leu Val Leu Gly Arg Gln Asn Glu Tyr Tyr Cys
     610                 615                 620                
 Arg Leu Asp Phe Leu Trp Lys Asn Lys Phe Lys Lys Glu Arg Glu Glu
 625                 630                 635                 640
 Ile Glu Thr Met Glu Asn Leu Asn Arg Val Leu Leu Glu Asn Val Leu
                 645                 650                 655    
 Pro Ala His Val Ala Glu His Phe Leu Ala Arg Ser Leu Lys Asn Glu
             660                 665                 670        
 Glu Leu Tyr His Gln Ser Tyr Asp Cys Val Cys Val Met Phe Ala Ser
         675                 680                 685            
 Ile Pro Asp Phe Lys Glu Phe Tyr Thr Glu Ser Asp Val Asn Lys Glu
     690                 695                 700                
 Gly Leu Glu Cys Leu Arg Leu Leu Asn Glu Ile Ile Ala Asp Phe Asp
 705                 710                 715                 720
 Asp Leu Leu Ser Lys Pro Lys Phe Ser Gly Val Glu Lys Ile Lys Thr
                 725                 730                 735    
 Ile Gly Ser Thr Tyr Met Ala Ala Thr Gly Leu Ser Ala Val Pro Ser
             740                 745                 750        
 Gln Glu His Ser Gln Glu Pro Glu Arg Gln Tyr Met His Ile Gly Thr
         755                 760                 765            
 Met Val Glu Phe Ala Phe Ala Leu Val Gly Lys Leu Asp Ala Ile Asn
     770                 775                 780                
 Lys His Ser Phe Asn Asp Phe Lys Leu Arg Val Gly Ile Asn His Gly
 785                 790                 795                 800
 Pro Val Ile Ala Gly Val Ile Gly Ala Gln Lys Pro Gln Tyr Asp Ile
                 805                 810                 815    
 Trp Gly Asn Thr Val Asn Val Ala Ser Arg Met Asp Ser Thr Gly Val
             820                 825                 830        
 Leu Asp Lys Ile Gln Val Thr Glu Glu Thr Ser Leu Val Leu Gln Thr
         835                 840                 845            
 Leu Gly Tyr Thr Cys Thr Cys Arg Gly Ile Ile Asn Val Lys Gly Lys
     850                 855                 860                
 Gly Asp Leu Lys Thr Tyr Phe Val Asn Thr Glu Met Ser Arg Ser Leu
 865                 870                 875                 880
 Ser Gln Ser Asn Val Ala Ser
                 885        



      <210> 2571
      <211> 140
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(140)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2571
 Pro Leu Leu Thr Pro Leu Val Ser Lys Val Thr Ala Ala Gly Val Pro
   1               5                  10                  15    
 Leu Phe Phe Phe Phe Phe Phe Phe Phe Xaa Asp Ile Val Ser Leu Cys
              20                  25                  30        
 His Pro Gly Trp Ser Ala Val Val Xaa Pro Xaa Leu Thr Ala Ala Ser
          35                  40                  45            
 Asn Ser Xaa Val Lys Gln Ser Ser His Leu Ser Leu Pro Ser Ser Trp
      50                  55                  60                
 Asp Asn Arg Tyr Ala Pro Pro Arg Pro Ala Asn Tyr Phe Tyr Tyr Phe
  65                  70                  75                  80
 Tyr Phe Leu Xaa Arg Leu Asp Leu Ala Leu Phe Pro Lys Leu Leu Leu
                  85                  90                  95    
 Asn Cys Trp Ala Gln Val Ile Leu Pro Ser Gln Pro Pro Lys Val Leu
             100                 105                 110        
 Gly Leu Xaa Ala Gln Ser Ser Glu Gly Gly Ile His Ser Gly Leu Ser
         115                 120                 125            
 Leu Pro Ser Pro Cys Phe Leu Leu Cys Asn Pro Ile
     130                 135                 140



      <210> 2572
      <211> 222
      <212> PRT
      <213> Homo sapiens


      <400> 2572
 Ala Ser Ser Thr Pro Gln Val Thr Ala Asn Glu Glu Ile Asn Val Thr
   1               5                  10                  15    
 Ser Thr Asp Ser Glu Val Glu Ile Val Thr Val Gly Glu Ser Tyr Arg
              20                  25                  30        
 Ser Arg Ser Thr Leu Gly His Ser Arg Ser His Trp Ser Gln Gly Ser
          35                  40                  45            
 Ser Ser His Ala Ser Arg Pro Gln Glu Pro Arg Asn Arg Ser Arg Ile
      50                  55                  60                
 Ser Thr Val Ile Gln Pro Leu Arg Gln Asn Ala Ala Glu Val Val Asp
  65                  70                  75                  80
 Leu Thr Val Asp Glu Asp Glu Pro Thr Val Val Pro Thr Thr Ser Ala
                  85                  90                  95    
 Arg Met Glu Ser Gln Ala Thr Ser Ala Ser Ile Asn Asn Ser Asn Pro
             100                 105                 110        
 Ser Thr Ser Glu Gln Ala Ser Asp Thr Ala Ser Ala Val Thr Ser Ser
         115                 120                 125            
 Gln Pro Ser Thr Val Ser Glu Thr Ser Ala Thr Leu Thr Ser Asn Ser
     130                 135                 140                
 Thr Thr Gly Thr Ser Ile Gly Asp Asp Ser Arg Arg Thr Thr Ser Ser
 145                 150                 155                 160
 Ala Val Thr Glu Thr Gly Pro Pro Ala Met Pro Arg Leu Pro Ser Cys
                 165                 170                 175    
 Cys Pro Gln His Ser Pro Cys Gly Gly Ser Ser Gln Asn His His Ala
             180                 185                 190        
 Leu Gly His Pro His Thr Ser Cys Phe Gln Gln His Gly His His Phe
         195                 200                 205            
 Gln His His His His His His His Thr Pro His Pro Cys Ile
     210                 215                 220        



      <210> 2573
      <211> 63
      <212> PRT
      <213> Homo sapiens


      <400> 2573
 Pro Cys Gly Pro Pro Gln Glu Lys Gly Ala Asp Cys His Leu Lys Ala
   1               5                  10                  15    
 Cys Pro Thr Ala Pro Cys Thr Thr Phe Arg Ala Ser Cys Cys Ser His
              20                  25                  30        
 Pro Ala Ser Cys Ser Arg Gly Lys Gln Ala Ser Met Ser Ser Thr Ser
          35                  40                  45            
 Ser Ser Ala Thr Val Pro Leu Pro Ala Asn Glu Met His Ser Gly
      50                  55                  60            



      <210> 2574
      <211> 120
      <212> PRT
      <213> Homo sapiens


      <400> 2574
 Gln Glu Leu Glu Arg Ser Met Ala Gln Arg Cys Val Cys Val Leu Ala
   1               5                  10                  15    
 Leu Val Ala Met Leu Leu Leu Val Phe Pro Thr Val Ser Arg Ser Met
              20                  25                  30        
 Gly Pro Arg Ser Gly Glu His Gln Arg Ala Ser Arg Ile Pro Ser Gln
          35                  40                  45            
 Phe Ser Lys Glu Glu Arg Val Ala Met Lys Glu Ala Leu Lys Val Phe
      50                  55                  60                
 Pro Thr Val Val Ser Thr Ser Phe Ile Gln His Glu Val Val Glu Glu
  65                  70                  75                  80
 Tyr Ser His Leu Phe Thr Ile Gln Gly Ser Asp Pro Ser Leu Gln Pro
                  85                  90                  95    
 Tyr Leu Leu Met Ala His Phe Asp Val Val Pro Ala Pro Glu Glu Gly
             100                 105                 110        
 Trp Glu Val Pro Pro Phe Ser Gly
         115                 120



      <210> 2575
      <211> 95
      <212> PRT
      <213> Homo sapiens


      <400> 2575
 Glu Asn Gly Ser Leu Arg Pro Lys Pro Thr Gly Ile Pro Leu Ser Ser
   1               5                  10                  15    
 Ala Arg Gly Asn Glu Leu Ser Pro Thr Arg Arg Arg Arg Arg Pro Trp
              20                  25                  30        
 Thr Pro Asn Pro Ala Gly Glu Thr Met Ser Ser Val Gln Gln Gln Pro
          35                  40                  45            
 Pro Pro Pro Arg Arg Val Thr Asn Val Gly Ser Leu Leu Leu Thr Pro
      50                  55                  60                
 Gln Glu Asn Glu Ser Leu Phe Thr Phe Leu Gly Lys Lys Cys Val Gly
  65                  70                  75                  80
 Ala Gly Arg Gly Gly Arg Ala Pro Pro Ser Arg Ala Ala Gly Glu
                  85                  90                  95



      <210> 2576
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 2576
 Met Leu Leu Trp Pro Leu Thr Gln Ala Gln Ser Ser Glu Met Ser Cys
   1               5                  10                  15    
 Cys Arg Leu Gly Ala Cys Phe Ile Thr Ser Leu Leu His Gln Ile Pro
              20                  25                  30        
 Ala Thr Ala Leu Leu Glu Gly Asn Leu Asp Ile Thr Leu Thr Val Gln
          35                  40                  45            
 Leu Gln Ile Leu Asp Ala His Asn Phe Pro Tyr Arg Leu Cys Leu Ile
      50                  55                  60                
 Asp Arg Cys Ile Cys Phe Ile Ser Ser Ser Thr Tyr Pro Gln Ile Asp
  65                  70                  75                  80
 Gly Leu Lys Ser Ser Arg Asp Ile Gly Asp Lys Ile Ser Phe Val Arg
                  85                  90                  95    
 Ser Asn Gly Ser Ile Asn Met Gly Lys Pro Phe Asn Phe
             100                 105                



      <210> 2577
      <211> 723
      <212> PRT
      <213> Homo sapiens


      <400> 2577
 Met Glu Gly Leu Asn Trp Leu Ser Leu Leu Ala Phe Ile Phe Leu Leu
   1               5                  10                  15    
 Cys Trp Met Leu Ser Ala Leu Lys His Gln Thr Pro Asn Ser Ser Ala
              20                  25                  30        
 Phe Gly Leu Leu Asp Leu His Gln Trp Phe Ala Thr Gly Ser Arg Met
          35                  40                  45            
 Asn Lys Asn Asn Lys Pro Ser Ser Phe Ile Ala Ile Arg Asn Ala Ala
      50                  55                  60                
 Phe Ser Glu Val Gly Ile Gly Ile Ser Ala Asn Ala Met Leu Leu Leu
  65                  70                  75                  80
 Phe His Ile Leu Thr Cys Leu Leu Lys His Arg Thr Lys Pro Ala Asp
                  85                  90                  95    
 Leu Ile Val Cys His Val Ala Leu Ile His Ile Ile Leu Leu Leu Pro
             100                 105                 110        
 Thr Glu Phe Ile Ala Thr Asp Ile Phe Gly Ser Gln Asp Ser Glu Asp
         115                 120                 125            
 Asp Ile Lys His Lys Ser Val Ile Tyr Arg Arg Asn Arg Gln Ser Gln
     130                 135                 140                
 His Phe His Ser Thr Asn Leu Ser Pro Lys Ala Pro Pro Glu Lys Met
 145                 150                 155                 160
 Ala Thr Gln Thr Ile Leu Leu Leu Val Ser Cys Phe Val Ile Val Tyr
                 165                 170                 175    
 Val Leu Asp Cys Val Val Ala Ser Cys Ser Gly Leu Val Trp Asn Ser
             180                 185                 190        
 Asp Pro Val Arg His Arg Val Gln Met Leu Val Asp Asn Gly Tyr Ala
         195                 200                 205            
 Thr Ile Ser Pro Ser Val Leu Pro Arg Leu Thr Ala Pro Asn Glu Trp
     210                 215                 220                
 Arg Ala Ser Val Tyr Leu Asn Asp Ser Leu Asn Lys Cys Ser Asn Gly
 225                 230                 235                 240
 Arg Leu Leu Cys Val Asp Arg Gly Leu Asp Glu Gly Pro Arg Ser Val
                 245                 250                 255    
 Pro Lys Cys Ser Glu Ser Glu Thr Asp Glu Asp Tyr Ile Val Leu Arg
             260                 265                 270        
 Ala Pro Leu Arg Glu Asp Glu Pro Lys Asp Gly Gly Ser Val Gly Asn
         275                 280                 285            
 Ala Ala Leu Val Ser Pro Glu Ala Ser Ala Glu Glu Glu Glu Glu Arg
     290                 295                 300                
 Glu Glu Gly Gly Glu Ala Cys Gly Leu Glu Arg Thr Gly Ala Gly Gly
 305                 310                 315                 320
 Glu Gln Val Asp Leu Gly Glu Leu Pro Asp His Glu Glu Lys Ser Asn
                 325                 330                 335    
 Gln Lys Val Ala Ala Ala Thr Leu Glu Asp Arg Thr Gln Asp Glu Pro
             340                 345                 350        
 Ala Glu Glu Ser Cys Gln Ile Val Leu Phe Gln Asn Asn Cys Met Asp
         355                 360                 365            
 Asn Phe Val Thr Ser Leu Thr Gly Ser Pro Tyr Glu Phe Phe Pro Thr
     370                 375                 380                
 Lys Ser Thr Ser Phe Cys Arg Glu Ser Cys Ser Pro Phe Ser Glu Ser
 385                 390                 395                 400
 Val Lys Ser Leu Glu Ser Glu Gln Ala Pro Lys Leu Gly Leu Cys Ala
                 405                 410                 415    
 Glu Glu Asp Pro Val Val Gly Ala Leu Cys Gly Gln His Gly Pro Leu
             420                 425                 430        
 Gln Asp Gly Val Ala Glu Gly Pro Thr Ala Pro Asp Val Val Val Leu
         435                 440                 445            
 Pro Lys Glu Glu Glu Lys Glu Glu Val Ile Val Asp Asp Met Leu Ala
     450                 455                 460                
 Asn Pro Tyr Val Met Gly Asp Glu Gly Glu Glu Glu Glu Glu Glu Phe
 465                 470                 475                 480
 Val Asp Asp Thr Leu Ala Asn Pro Tyr Val Met Gly Val Gly Leu Pro
                 485                 490                 495    
 Gly Arg Gly Gly Glu Glu Glu Glu Glu Glu Glu Val Val Asp Asp Thr
             500                 505                 510        
 Leu Ala Ser Leu Tyr Lys Met Gly Glu Glu His Arg His Lys Gly Leu
         515                 520                 525            
 Ala Pro Leu Trp Glu Gly Gly Gln Lys Pro Ser Gln Lys Leu Pro Pro
     530                 535                 540                
 Lys Lys Pro Asp Leu Arg Gln Val Pro Gln Pro Leu Ala Ser Glu Val
 545                 550                 555                 560
 Pro Gln Arg Arg Gln Glu Arg Ala Val Val Thr Glu Gly Arg Pro Leu
                 565                 570                 575    
 Glu Ala Ser Arg Ala Leu Pro Ala Lys Pro Arg Ala Phe Thr Leu Tyr
             580                 585                 590        
 Pro Arg Ser Phe Ser Val Glu Gly Gln Glu Ile Pro Val Ser Ile Ser
         595                 600                 605            
 Val Tyr Trp Glu Pro Glu Gly Ser Gly Leu Asp Asp His Arg Ile Lys
     610                 615                 620                
 Arg Lys Glu Glu His Leu Ser Val Val Ser Gly Ser Phe Ser Gln Arg
 625                 630                 635                 640
 Asn His Leu Pro Ser Ser Gly Thr Ser Thr Pro Ser Ser Met Val Asp
                 645                 650                 655    
 Ile Pro Pro Pro Phe Asp Leu Ala Cys Ile Thr Lys Lys Pro Ile Thr
             660                 665                 670        
 Lys Ser Ser Pro Ser Leu Leu Ile Asp Ser Asp Ser Pro Asp Lys Tyr
         675                 680                 685            
 Lys Lys Lys Lys Ser Ser Phe Lys Arg Phe Leu Ala Leu Met Phe Asn
     690                 695                 700                
 Lys Met Glu Arg Pro Gly Thr Met Ala His Ala Cys His Pro Ser Thr
 705                 710                 715                 720
 Leu Gly Ser
            



      <210> 2578
      <211> 119
      <212> PRT
      <213> Homo sapiens


      <400> 2578
 Met His Leu Leu Gln Ala Ala Leu Leu Leu Ala Val Pro Cys Leu Leu
   1               5                  10                  15    
 Cys Tyr Val Ala Val Gly Tyr Ala Phe Ser Val Leu Leu Thr Leu Leu
              20                  25                  30        
 Leu Thr Ala Pro Ala Leu Leu Pro Asp Asp Phe Glu Gly Phe Asn Ile
          35                  40                  45            
 Arg Glu Lys Thr Gly Trp Tyr Gly Lys Lys Glu Gly Met Val Thr Leu
      50                  55                  60                
 Ser Asn Pro Gln Val Ala Arg Glu Lys Glu Gln Phe Asn Asp Leu Tyr
  65                  70                  75                  80
 Phe Asn Ala Lys Gln Ala Glu Gln Lys Gly Tyr Leu Asn Thr Ala Arg
                  85                  90                  95    
 Arg Glu Ala Ser Leu Ala Phe Lys Val Thr Glu Thr Thr His Asn Lys
             100                 105                 110        
 Ser Gly Leu Ile Thr Glu Ser
         115                



      <210> 2579
      <211> 345
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(345)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2579
 Ala Thr Val Gly Gly Arg Glu Ile Tyr Val Lys Gly Phe Val His Tyr
   1               5                  10                  15    
 Lys Val Arg Ala Leu Phe Pro Cys Glu Lys Pro Pro Arg Pro Thr Glu
              20                  25                  30        
 Met Ser Arg His His Ser Arg Phe Glu Arg Asp Tyr Arg Val Gly Trp
          35                  40                  45            
 Asp Arg Arg Glu Trp Ser Val Asn Gly Thr His Gly Thr Thr Ser Ile
      50                  55                  60                
 Cys Ser Val Thr Ser Gly Ala Gly Glu Arg His Ser Gln Gln Pro Gln
  65                  70                  75                  80
 Arg Pro Ala Arg Pro Pro Ala Ala Ala Arg Gly Ala Leu Pro Ala Ala
                  85                  90                  95    
 His Pro Gly Tyr Ser Ser Cys Ser Leu Arg Pro Pro Ala Ala Ala Arg
             100                 105                 110        
 Pro Ser Pro Ala Ser Trp Pro Ala Leu Arg Leu Arg Ser Pro Pro Arg
         115                 120                 125            
 Leu Pro Ala Ser Pro Lys Gly Thr Val Ser Pro Arg Asp Trp Arg Pro
     130                 135                 140                
 Ala Ser Gly Gly Gly Arg Arg Leu Ser Ile Ser Pro His Pro Gly Ile
 145                 150                 155                 160
 Thr Asp Glu Pro Pro Ser Lys Gln Met Arg Glu Ser Asp Asn Pro Gly
                 165                 170                 175    
 Thr Gly Pro Trp Gly Pro Arg Trp Pro Pro Gly Thr Ser Pro Pro Xaa
             180                 185                 190        
 Ser His Thr Pro Met Glu Trp Pro Ser Leu Pro Pro Ser Pro Gly Cys
         195                 200                 205            
 Glu Arg Pro Gly Pro Gly His Trp Gly Asp Pro Leu Thr Ala Ser Pro
     210                 215                 220                
 Arg Gly Ala Pro Ala Pro Ala Asp Ala Arg Pro Leu Pro Leu Pro Gln
 225                 230                 235                 240
 Pro Pro Ser Gln Pro Leu Ser Ser Gly Trp Ser Thr Cys Leu Pro Arg
                 245                 250                 255    
 Pro Cys Met Pro Ala Leu Ser Pro Trp Pro Cys Pro His Cys Pro Val
             260                 265                 270        
 Trp Gly Arg Trp Pro Ala Gln Asp Pro Pro Leu Trp Ala Thr Ala Thr
         275                 280                 285            
 Trp Gln Gly Pro Cys Cys Leu His Arg Arg Gln Pro Ser Arg Pro Pro
     290                 295                 300                
 Leu Ser Pro Val Val Pro Leu Pro Pro Met Gly Pro Pro Gln Pro Thr
 305                 310                 315                 320
 Arg Pro Thr Gly Cys Arg Cys Cys Gly Pro Leu Ala Trp Gly Ser Met
                 325                 330                 335    
 Ser Ser Pro Thr Arg Gly Thr Pro Glu
             340                 345



      <210> 2580
      <211> 511
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(511)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2580
 Met Glu Glu Lys Thr Asn Val Gln Leu Pro Pro Gly Gln Thr Glu Gln
   1               5                  10                  15    
 His Val Glu Ile His Ile Met Asn Phe Cys Ser Lys Asn His His Arg
              20                  25                  30        
 Ile Thr Pro Glu Lys Pro Lys Glu Leu Thr Asp Pro Phe Lys Glu Ala
          35                  40                  45            
 Ala Cys Cys Cys Lys Leu Tyr Glu Ile Asp Lys Lys Leu Tyr Arg Met
      50                  55                  60                
 Ala Glu Trp Ile Lys Ile His Lys Pro Ser Ile Cys Cys Leu Gln Glu
  65                  70                  75                  80
 Thr His Leu Thr His Lys Asp Ser His Lys Leu Lys Val Ser Ile Thr
                  85                  90                  95    
 Phe Lys Asp Leu Ala Val Arg Phe Ser Glu Glu Glu Trp Arg Leu Leu
             100                 105                 110        
 Glu Glu Gly Gln Arg Glu Phe Tyr Arg Asp Val Met Arg Glu Asn Tyr
         115                 120                 125            
 Glu Thr Leu Val Ser Val Glu Pro Gly Arg Ala Val Gly Gly Gly Ser
     130                 135                 140                
 His Ala Asp Glu Gly Gln Glu Pro Ala Gly Cys Gly Val Ser Pro Gly
 145                 150                 155                 160
 Pro Gly Ala Ala Gly Glu Gly Asp Pro Arg Val Leu Val Trp Arg Ser
                 165                 170                 175    
 Gln Gly Arg Tyr Gly Gln Pro Arg Glu Arg Gly Arg Gly Ala Ser Leu
             180                 185                 190        
 Asp Gly Glu Arg Ala Ser Pro Glu Ala Ala Asp Gly Lys Arg Ala Leu
         195                 200                 205            
 Pro Ser Pro Arg Pro Ala Gln Leu Pro Ser Arg Arg Pro Tyr Gln Pro
     210                 215                 220                
 Ala Pro Pro Gly Pro Thr Pro Thr Asp Ser Ser Cys Ser Ser Gly Pro
 225                 230                 235                 240
 Thr Gly Asp Gly Val Gln Gly Ser Pro Leu Pro Ile Arg Ile Ser Pro
                 245                 250                 255    
 Gly Asn Ser Pro Leu Pro Arg Pro His Gln Leu Ser Glu Gly Asn Pro
             260                 265                 270        
 Cys Ala Trp Ala Pro Ala Pro Arg Asp Ile Pro Lys Leu Leu Ala Thr
         275                 280                 285            
 Ser Pro Xaa Pro Gly His Val Gln Ala Asn Gln Ser Arg Pro Gly Ala
     290                 295                 300                
 Trp Glu Pro Ala Leu Gly Arg Ser Asp Gln Arg Ala Cys Ser Ala Ser
 305                 310                 315                 320
 Gly Ser Ala Glu Leu Cys Glu Arg Trp Pro Gln Gln Ala Pro Ala Pro
                 325                 330                 335    
 Pro Glu Glu Pro Pro Pro Ala Ser Pro His Pro Ala Ala Pro Thr Gly
             340                 345                 350        
 Pro Gly Phe Trp Glu Ser Cys Gly Glu Pro Gly Ala Ala Pro Gly Lys
         355                 360                 365            
 Gly Ser Ala Pro Lys Pro Ser Pro Leu His Cys Leu Glu Ser Ala Leu
     370                 375                 380                
 Arg Gly Ile Leu Pro Glu Gly Pro Cys Ala Ser Pro Ala Trp Glu Ala
 385                 390                 395                 400
 Pro Ala Pro Ala Pro Ala Pro Ala Pro Ala Arg Ala Ser Ala Ala Ala
                 405                 410                 415    
 Glu Gly Glu Asp Pro Arg Pro Glu Pro Glu Leu Trp Lys Pro Leu Pro
             420                 425                 430        
 Gln Glu Arg Asp Arg Leu Pro Ser Cys Lys Pro Pro Val Pro Leu Ser
         435                 440                 445            
 Pro Cys Pro Gly Gly Thr Pro Ala Gly Ser Ser Gly Gly Ser Pro Gly
     450                 455                 460                
 Glu Ala Pro Gly Glu Gln Ser Pro Gly Thr Ala Ala Ala Ser Val Gln
 465                 470                 475                 480
 Val Ser Pro Ala His Trp Pro Cys Phe Ser Ser Pro Val Arg Tyr Ser
                 485                 490                 495    
 Ser Gly Ser Leu Pro Gly Phe Ser Ala Gly Glu Lys Ala Gln Gly
             500                 505                 510    



      <210> 2581
      <211> 170
      <212> PRT
      <213> Homo sapiens


      <400> 2581
 Pro Arg Leu Leu Met Glu Ala Gly Pro His Pro Arg Pro Gly His Cys
   1               5                  10                  15    
 Cys Lys Pro Gly Gly Arg Leu Asp Met Asn His Gly Phe Val His His
              20                  25                  30        
 Ile Arg Arg Asn Gln Ile Ala Arg Asp Asp Tyr Asp Lys Lys Val Lys
          35                  40                  45            
 Gln Ala Ala Lys Glu Lys Val Arg Arg Arg His Thr Pro Ala Pro Thr
      50                  55                  60                
 Arg Pro Arg Lys Pro Asp Leu Gln Val Tyr Leu Pro Arg His Arg Asp
  65                  70                  75                  80
 Val Ser Ala His Pro Arg Asn Pro Asp Tyr Glu Glu Ser Gly Glu Ser
                  85                  90                  95    
 Ser Ser Ser Gly Gly Ser Glu Leu Glu Pro Ser Gly His Gln Leu Phe
             100                 105                 110        
 Cys Leu Glu Tyr Glu Ala Asp Ser Gly Glu Val Thr Ser Val Ile Val
         115                 120                 125            
 Tyr Gln Gly Asp Asp Pro Gly Lys Val Ser Glu Lys Val Ser Ala His
     130                 135                 140                
 Thr Pro Leu Asp Pro Pro Met Arg Glu Ala Leu Lys Leu Arg Ile Gln
 145                 150                 155                 160
 Glu Glu Ile Ala Lys Arg Gln Ser Gln His
                 165                 170



      <210> 2582
      <211> 398
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(398)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2582
 Gly Gly Ser Ser Ala Arg Pro Arg Ala Ser Ser Arg Arg Met Leu Ser
   1               5                  10                  15    
 Arg Lys Lys Thr Lys Asn Glu Val Ser Lys Pro Ala Glu Val Gln Gly
              20                  25                  30        
 Lys Tyr Val Lys Lys Glu Thr Ser Pro Leu Leu Arg Asn Leu Met Pro
          35                  40                  45            
 Ser Phe Ile Arg His Gly Pro Thr Ile Pro Arg Arg Thr Asp Ile Cys
      50                  55                  60                
 Leu Pro Asp Ser Ser Pro Asn Ala Phe Ser Thr Ser Gly Asp Gly Val
  65                  70                  75                  80
 Val Ser Arg Asn Gln Ser Phe Leu Arg Thr Pro Ile Gln Arg Thr Pro
                  85                  90                  95    
 His Glu Ile Met Arg Arg Glu Ser Asn Arg Leu Ser Ala Pro Ser Tyr
             100                 105                 110        
 Leu Ala Arg Ser Leu Ala Asp Val Pro Arg Glu Tyr Gly Ser Ser Gln
         115                 120                 125            
 Ser Phe Val Thr Glu Val Ser Phe Ala Val Glu Asn Gly Asp Ser Gly
     130                 135                 140                
 Ser Arg Tyr Tyr Tyr Ser Asp Asn Phe Phe Asp Gly Gln Arg Lys Arg
 145                 150                 155                 160
 Pro Leu Gly Asp Arg Ala His Glu Asp Tyr Arg Tyr Tyr Glu Tyr Asn
                 165                 170                 175    
 His Asp Leu Phe Gln Arg Met Pro Gln Asn Gln Gly Arg His Ala Ser
             180                 185                 190        
 Gly Ile Gly Arg Val Ala Ala Thr Ser Leu Gly Asn Leu Thr Asn His
         195                 200                 205            
 Gly Ser Glu Asp Leu Pro Leu Pro Pro Gly Trp Ser Val Asp Trp Thr
     210                 215                 220                
 Met Arg Gly Arg Lys Tyr Tyr Ile Asp His Asn Thr Asn Thr Thr His
 225                 230                 235                 240
 Trp Ser His Pro Leu Glu Arg Glu Gly Leu Pro Pro Gly Trp Glu Arg
                 245                 250                 255    
 Val Glu Ser Ser Glu Phe Gly Thr Tyr Tyr Val Asp His Thr Asn Lys
             260                 265                 270        
 Lys Ala Gln Tyr Arg His Pro Cys Ala Pro Thr Cys Thr Ser Val Xaa
         275                 280                 285            
 Ser Thr Thr Ser Cys His Ile Ala Ser Arg Gln Gln Thr Glu Arg Asn
     290                 295                 300                
 Gln Ser Leu Leu Val Pro Ala Asn Pro Tyr His Thr Ala Glu Ile Pro
 305                 310                 315                 320
 Asp Trp Leu Gln Val Tyr Ala Arg Ala Pro Val Lys Tyr Asp His Ile
                 325                 330                 335    
 Leu Lys Trp Glu Leu Phe Gln Leu Ala Asp Leu Asp Thr Tyr Gln Gly
             340                 345                 350        
 Met Leu Lys Leu Leu Phe Met Lys Glu Leu Glu Gln Ile Val Lys Met
         355                 360                 365            
 Tyr Glu Ala Tyr Arg Gln Ala Leu Leu Thr Glu Leu Glu Asn Arg Lys
     370                 375                 380                
 Gln Arg Gln Gln Trp Tyr Ala Gln Gln His Gly Lys Asn Phe
 385                 390                 395            



      <210> 2583
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 2583
 Leu Gly Thr Arg Gly Cys Leu Asn Met Ala Ala Pro Leu Ser Val Glu
   1               5                  10                  15    
 Val Glu Phe Gly Gly Gly Ala Glu Leu Leu Phe Asp Gly Ile Lys Lys
              20                  25                  30        
 His Arg Val Thr Leu Pro Gly Gln Glu Glu Pro Trp Asp Ile Arg Asn
          35                  40                  45            
 Leu Leu Ile Trp Ile Lys Lys Asn Leu Leu Lys Glu Arg Pro Glu Leu
      50                  55                  60                
 Phe Ile Gln Gly Asp Ser Val Arg Pro Gly Ile Leu Val Leu Ile Asn
  65                  70                  75                  80
 Asp Ala Asp Trp Glu Leu Leu Gly Glu Leu Asp Tyr Gln Leu Gln Asp
                  85                  90                  95    
 Gln Asp Ser Val Leu Phe Ile Ser Thr Leu His Gly Gly
             100                 105                



      <210> 2584
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 2584
 Val Arg Ser Met Ser Cys Pro Pro Ser Trp Pro Tyr Cys Ala Pro Cys
   1               5                  10                  15    
 Pro Thr Asn Ile Gly Glu Ser Thr Ser Pro Leu Arg Lys Thr Ile Glu
              20                  25                  30        
 Thr Pro Thr Leu Trp Asp Pro Lys Ala Pro Ser Cys Ser Leu Glu Leu
          35                  40                  45            
 Pro Pro Trp Val Leu Ala Ser Pro Gln Arg Ser Arg Gly Thr Ala Leu
      50                  55                  60                
 Pro Phe Leu Pro Ser Asn Val Leu Pro Ser Leu Ala Leu Pro Ser Thr
  65                  70                  75                  80
 Ser Phe Leu Cys Arg Pro Leu Leu Ser His Leu Val Thr Ser Leu Leu
                  85                  90                  95    
 Ala Gly Pro Gly Ala His Asp Gly His Leu Arg Lys Glu Gly Trp Arg
             100                 105                 110        
 Ser Thr Pro Glu Met Thr Ser Leu Pro Ala Pro Glu His Pro Ala Ser
         115                 120                 125            
 Pro Cys Asp Ser Val Leu Cys Ser Pro Asp Val Ser Met Cys Thr Leu
     130                 135                 140                
 Gly Pro Ala Ala Arg Trp Asp Ala Gln Ala Lys Ser Ala Pro Leu Pro
 145                 150                 155                 160
 Pro Cys Cys Thr Asp Cys Lys Ser Phe Pro His Leu Gln Arg Pro Trp
                 165                 170                 175    
 Ala Gln Pro His Thr Ser Gln Ala Thr Ser Val Asp Ser Gly Glu Ala
             180                 185                 190        
 Gly Thr Lys Gly Met Ser Gln Phe Thr Val Trp Thr Trp Trp Arg Ser
         195                 200                 205            
 Arg Pro Cys Glu Thr Arg Gln Gly Glu Gly Ile Gly Asn Trp Gly Tyr
     210                 215                 220                
 Ser Val Thr Pro Gly Pro Pro Gly Ser Gln Asn Leu Pro Ala Arg Leu
 225                 230                 235                 240
 Asp Gly Gln Gly Leu Ala Ser
                 245        



      <210> 2585
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 2585
 Asn Ala His Ser Leu Pro Ile Glu Trp Ala Phe Cys Lys Ile Glu Asn
   1               5                  10                  15    
 Leu Cys Gly Lys Cys Val Tyr Met Cys Met Cys Ser Gln Asn Lys Asn
              20                  25                  30        
 Asn Gln Leu Lys Phe Ser Phe Ile Pro Gly Arg Trp Cys Ala Ser Leu
          35                  40                  45            
 Lys Met Tyr Ser Lys Gly Gln Arg Ser Leu Met Tyr Pro Cys Arg Tyr
      50                  55                  60                
 His Gln Arg Met Leu Leu Val Ser Arg Tyr Leu Asp Thr Val Leu Leu
  65                  70                  75                  80
 Asp Trp Asp Pro Pro Gly Pro Leu Pro Glu Gly Arg Gln His Ser Pro
                  85                  90                  95    
 Gly Arg Arg Gln Arg Asp Leu Ala Ser Ala Leu Leu Cys
             100                 105                



      <210> 2586
      <211> 368
      <212> PRT
      <213> Homo sapiens


      <400> 2586
 Met Leu Tyr Trp Leu Met Pro Lys Gly Lys Leu Leu Trp Ile Ala Ser
   1               5                  10                  15    
 Phe Leu Thr Arg Leu Gln Gly Ile Gln His Thr Leu Pro Arg Val Glu
              20                  25                  30        
 Glu Lys Ser Ile Gln Ser Val Lys Asp Asp Asn Ile Tyr His Pro His
          35                  40                  45            
 Pro Arg Pro Arg Ile Ala Val Val Gly Ser Ser Ser Thr Val Ile Ser
      50                  55                  60                
 Tyr Ser Pro Gly Glu Tyr Ala Phe Thr Asn Gly Thr Ser Arg Cys Pro
  65                  70                  75                  80
 Ser Leu Ser Leu Ala Ala Gly Pro Arg Leu Ile Thr Asn Gly Pro Trp
                  85                  90                  95    
 Glu Ala His Glu Val Gln Arg Glu Ser Thr Ile Ala Leu Met Lys Leu
             100                 105                 110        
 Leu Gln Val Leu Glu Gln Lys Val Arg Leu Arg Glu Gly His Ser Leu
         115                 120                 125            
 Gly Thr Val Lys Met Ser Lys Asn Ile Asn Pro Met Gly His Val Ser
     130                 135                 140                
 Asn Pro Pro Thr Ser Tyr Pro Asp Glu Leu Ile Thr Lys Gln Val Cys
 145                 150                 155                 160
 Pro Gly Ser His Pro Lys Arg Pro Gly Glu Val Lys His Asn Glu Glu
                 165                 170                 175    
 Val Pro Thr Ser Gln Asp Arg Asp Thr Cys Thr Thr Gln Glu Thr Gln
             180                 185                 190        
 Tyr Ser Val Arg Lys Ile Ile Ser Ala Glu Asp Asp Phe Thr Val Lys
         195                 200                 205            
 Asn Tyr Asn His Ile Arg Asn Lys Phe Thr Ile Pro Ser Arg Lys Gly
     210                 215                 220                
 Gln Gln Ala His Arg Ala Trp Leu Asn Lys Ala Ile Pro Gln Pro Met
 225                 230                 235                 240
 Pro Thr Ser Ala Thr Ser Leu Leu Ala Ala Leu Val Arg Ala Ala Lys
                 245                 250                 255    
 His Arg Asn Gln Gln Pro Gln Asp Leu Ala Gln Ser Ser Ser His His
             260                 265                 270        
 Ile Tyr Leu Phe Ile Thr Ile Thr Phe Gly Ser Leu Arg Asp Ser Glu
         275                 280                 285            
 Leu Lys Ser Lys Arg Gly Pro Asp Pro Gln Leu Ser Leu Glu Leu Glu
     290                 295                 300                
 Met Val Ala Lys Ala Lys Ala Val Lys Pro Glu Asn Ser Arg Arg Trp
 305                 310                 315                 320
 Phe Ser Gly Asn Gln Leu Gly Ser Ile Ile Asn Ser Pro Lys Lys Gly
                 325                 330                 335    
 Ser Ala Val Leu Glu Gly Thr Phe Gln Glu Lys Gln Lys Trp Asp Ala
             340                 345                 350        
 Arg Leu Thr Lys Gly Asp Cys Leu Ala Thr Asn Val Leu Asn Arg Val
         355                 360                 365            





      <210> 2587
      <211> 128
      <212> PRT
      <213> Homo sapiens


      <400> 2587
 Met Ala Cys Arg Val Leu Gln Gly Leu Pro Phe Ala Cys Leu Ser Ser
   1               5                  10                  15    
 Pro Ile Cys Ser His Ser Ala Leu Thr Leu Asp His Ser Leu Leu Cys
              20                  25                  30        
 Leu Asn Phe Phe Phe Asn Pro Tyr Ala Leu Leu Pro Asn Phe Tyr Leu
          35                  40                  45            
 Phe Gly Lys Phe Gln Leu Arg Ile Pro Ser Ser Gly Lys Pro Phe Leu
      50                  55                  60                
 Thr Ser Glu Asp Gln Asp Pro Ala Gly Ile Phe Glu Leu Val Glu Val
  65                  70                  75                  80
 Val Gly Asn Gly Thr Tyr Gly Gln Val Tyr Lys Val Arg Arg Met Val
                  85                  90                  95    
 Trp Lys Tyr Asp Leu His Ile Cys Arg Ala Val Leu Gly Gly Val Glu
             100                 105                 110        
 Gly Ser Arg Phe Leu Val Cys Arg Ser Glu Gly Gly Tyr Gly Arg Cys
         115                 120                 125            





      <210> 2588
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2588
 Met Leu Leu Pro Leu Phe Leu Leu Ile His Thr Gly Ile Gly Pro Ser
   1               5                  10                  15    
 Tyr Ser Ala Ser Asp Arg Ala Glu Pro Arg Pro Ser Pro Gly Gly Arg
              20                  25                  30        
 Leu Thr Ala Arg Ile Trp Ile Lys Gly Val Lys Glu Asp Gly Gly Thr
          35                  40                  45            
 Met Gln Gly Ala Val Asp Trp Gly Glu Gly Val Glu Arg Cys Ala Gly
      50                  55                  60                
 Arg Ile Thr Ala Ser His Lys Val Ala Asp Lys Trp His Ser Ser Arg
  65                  70                  75                  80
 Asn Ser Leu Gly Gly Ser Pro Glu Pro Gly Thr Pro Ala Pro Gly Pro
                  85                  90                  95    
 Trp Val Gly Phe Cys His Pro Cys Leu Pro Ala Ser Pro Leu Ser Trp
             100                 105                 110        
 Thr Ala Thr Gly Thr Ala Ala Thr His Ala Gln Cys Ala Glu Arg Val
         115                 120                 125            
 His Asn Leu Cys Arg Arg Ala Lys Pro Ser
     130                 135            



      <210> 2589
      <211> 65
      <212> PRT
      <213> Homo sapiens


      <400> 2589
 Met Gln Ala Gly Leu Ala Arg Ala Met Val Leu Ala Ala Gly Trp Ser
   1               5                  10                  15    
 Arg Val Ala Ser Ala Gly Ala Ala Gly Asp Thr Ser Pro Val Pro Arg
              20                  25                  30        
 Ala Leu Ser Asp Leu Arg Ile Thr Gln Lys Cys Gly Leu Leu Val Pro
          35                  40                  45            
 Lys Ala Val Ser Trp Lys Ser Leu Phe Leu Phe Pro Ile Thr Val Glu
      50                  55                  60                
 Leu
  65



      <210> 2590
      <211> 115
      <212> PRT
      <213> Homo sapiens


      <400> 2590
 Met Ala Val Ala Val Leu Leu Cys Gly Cys Ile Val Ala Thr Val Ser
   1               5                  10                  15    
 Phe Phe Trp Glu Glu Ser Leu Thr Gln His Val Ala Gly Leu Leu Phe
              20                  25                  30        
 Leu Met Thr Gly Ile Phe Cys Thr Ile Ser Leu Cys Thr Tyr Ala Ala
          35                  40                  45            
 Ser Ile Ser Tyr Asp Leu Asn Arg Leu Pro Lys Leu Ile Tyr Ser Leu
      50                  55                  60                
 Pro Ala Asp Val Glu His Gly Tyr Ser Trp Ser Ile Phe Cys Ala Trp
  65                  70                  75                  80
 Cys Ser Leu Gly Phe Ile Val Ala Ala Gly Gly Leu Cys Ile Ala Tyr
                  85                  90                  95    
 Pro Phe Ile Ser Arg Thr Lys Ile Ala Gln Leu Lys Ser Gly Arg Asp
             100                 105                 110        
 Ser Thr Val
         115



      <210> 2591
      <211> 147
      <212> PRT
      <213> Homo sapiens


      <400> 2591
 Ser Ser Ala Phe Arg Ser Val Leu Leu Glu Met Arg Val Ser Ser Arg
   1               5                  10                  15    
 Thr Cys Ile Ile Asp Thr Leu Gln Gly Ala Val Pro Thr Tyr Pro Gly
              20                  25                  30        
 Ser Gly Thr Pro Ala Leu Gly Glu Lys Ser Gly Ser Leu Gly Leu Val
          35                  40                  45            
 Ala Trp Ser Phe Pro Arg Pro Gly Glu Ser Ser Ser Thr Ala Pro Arg
      50                  55                  60                
 Arg Ser Pro Cys Cys Cys Pro Trp Ser Pro Ser His Ser Ser Pro Ala
  65                  70                  75                  80
 Ser Phe Pro Pro Leu Arg Pro Ser Ala Pro Ala Thr Arg Ala Pro Arg
                  85                  90                  95    
 Glu Gly Leu Pro Thr Pro Ala Ser Arg Ala His Phe Pro Gly Ala Thr
             100                 105                 110        
 Ala Ile Pro Lys Thr Ser Gly Leu Leu Ile Ala Thr Ala Ser Leu Cys
         115                 120                 125            
 Trp Gly Gln Thr His Gln Pro Cys Pro Leu Pro Leu Ala Arg Phe Leu
     130                 135                 140                
 Gly Lys Arg
 145        



      <210> 2592
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 2592
 Gly His Cys Pro Val Leu Arg Val Val Thr Glu Lys His Cys Arg Ala
   1               5                  10                  15    
 Cys Glu Lys Glu Gly Met Asp Ser Ser Ile His Leu Ser Ser Leu Ile
              20                  25                  30        
 Ser Arg His Asp Asp Glu Ala Thr Arg Thr Ser Thr Ser Glu Gly Leu
          35                  40                  45            
 Glu Glu Gly Glu Val Glu Gly Glu Thr Leu Leu Ile Val Glu Ser Glu
      50                  55                  60                
 Asp Gln Ala Ser Val Asp Leu Ser His Asp Gln Ser Gly Asp Ser Leu
  65                  70                  75                  80
 Asn Ser Asp Glu Gly Asp Val Ser Trp Met Glu Glu Gln Leu Ser Tyr
                  85                  90                  95    
 Phe Cys Asp Lys Cys Gln Lys Trp Ile Pro Ala Ser Lys Glu Leu Leu
             100                 105                 110        
 Asn Ser Phe Asp Leu Ser Ile Pro Val
         115                 120    



      <210> 2593
      <211> 74
      <212> PRT
      <213> Homo sapiens


      <400> 2593
 Met Gly Arg Val Ser Gly Leu Val Pro Ser Arg Phe Leu Thr Leu Leu
   1               5                  10                  15    
 Ala His Leu Val Val Val Ile Thr Leu Phe Trp Ser Arg Asp Ser Asn
              20                  25                  30        
 Ile Gln Ala Cys Leu Pro Leu Thr Phe Thr Pro Glu Glu Tyr Asp Lys
          35                  40                  45            
 Gln Asp Ile His Ala Leu Pro Ala Val Thr Glu Met Ala Leu Phe Val
      50                  55                  60                
 Thr Val Phe Gly Leu Lys Lys Lys Pro Phe
  65                  70                



      <210> 2594
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 2594
 Met Ser Phe Ile Cys Phe Leu Asn Phe Val Val Pro Thr Ser Ala Ile
   1               5                  10                  15    
 Pro Leu Arg Leu Trp Asn Tyr Cys Gly Met Asn Ser Pro Ser Arg Ser
              20                  25                  30        
 Trp Asp Cys Leu Cys Thr Pro Leu Ser Arg Gln Ser Ala Pro Val Ser
          35                  40                  45            
 His Met Ala Lys Val Trp
      50                



      <210> 2595
      <211> 348
      <212> PRT
      <213> Homo sapiens


      <400> 2595
 Arg Tyr Arg Ala Ala Arg Asn Val Met Lys Asp Gln Arg Leu Val Phe
   1               5                  10                  15    
 His Ser Lys Val Arg Ser Ser Gly Tyr Ala Ser Ala Pro His Val Thr
              20                  25                  30        
 Met Phe Ser Pro Lys Thr Asn Ile Lys Ser Glu Gly Lys Gly Ser Ser
          35                  40                  45            
 Arg Ser Arg Ser Ser Cys Ala Arg Glu Ala Tyr Pro Val Glu Cys Ala
      50                  55                  60                
 Val Pro Thr Lys Pro Gly Pro Gln Val Ala Ala Ala Pro Thr Cys Thr
  65                  70                  75                  80
 Arg Val Cys Cys Ile Gln Tyr Ser Gly Asp Gly Gln Trp Leu Ala Cys
                  85                  90                  95    
 Gly Leu Ala Asn His Leu Leu Leu Val Phe Asp Ala Ser Leu Thr Gly
             100                 105                 110        
 Thr Pro Ala Val Phe Ser Gly His Asp Gly Ala Val Asn Ala Val Cys
         115                 120                 125            
 Trp Ser Gln Asp Arg Arg Trp Leu Leu Ser Ala Ala Arg Asp Gly Thr
     130                 135                 140                
 Leu Arg Met Trp Ser Ala Arg Gly Ala Glu Leu Ala Leu Leu Arg Tyr
 145                 150                 155                 160
 Lys Gln Lys Ser Lys Ser Lys Leu Ile Cys Arg Leu Ser Thr Thr Gly
                 165                 170                 175    
 Ala Val Asp Met Thr Ser Leu Ser Ala Val Asn Asp Phe Tyr Ser His
             180                 185                 190        
 Ile Val Leu Ala Ala Gly Arg Asn Arg Thr Val Glu Val Phe Asp Leu
         195                 200                 205            
 Asn Ala Gly Cys Ser Ala Ala Val Ile Val Glu Ala His Ser Arg Pro
     210                 215                 220                
 Val His Gln Ile Cys Gln Asn Lys Gly Ser Ser Phe Thr Thr Gln Gln
 225                 230                 235                 240
 Pro Gln Ala Tyr Asn Leu Phe Leu Thr Thr Ala Ile Gly Asp Gly Met
                 245                 250                 255    
 Arg Leu Trp Asp Leu Arg Thr Leu Arg Cys Glu Arg His Phe Glu Gly
             260                 265                 270        
 His Pro Thr Arg Gly Tyr Pro Cys Gly Ile Ala Phe Ser Pro Cys Gly
         275                 280                 285            
 Arg Phe Ala Ala Cys Gly Ala Glu Asp Arg His Ala Tyr Val Tyr Glu
     290                 295                 300                
 Met Gly Ser Ser Thr Phe Ser His Arg Leu Ala Gly His Thr Asp Thr
 305                 310                 315                 320
 Val Thr Gly Val Ala Phe Asn Pro Ser Ala Pro Gln Leu Ala Thr Ala
                 325                 330                 335    
 Thr Leu Asp Gly Lys Leu Gln Leu Phe Leu Ala Glu
             340                 345            



      <210> 2596
      <211> 251
      <212> PRT
      <213> Homo sapiens


      <400> 2596
 Arg Ser Gly Ser Leu Met Ala Ala Ala Ala Ala Thr Lys Ile Leu Leu
   1               5                  10                  15    
 Cys Leu Pro Leu Leu Leu Leu Leu Ser Gly Trp Ser Arg Ala Gly Arg
              20                  25                  30        
 Ala Asp Pro His Ser Leu Cys Tyr Asp Ile Thr Val Ile Pro Lys Phe
          35                  40                  45            
 Arg Pro Gly Pro Arg Trp Cys Ala Val Gln Gly Gln Val Asp Glu Lys
      50                  55                  60                
 Thr Phe Leu His Tyr Asp Cys Gly Asn Lys Thr Val Thr Pro Val Ser
  65                  70                  75                  80
 Pro Leu Gly Lys Lys Leu Asn Val Thr Thr Ala Trp Lys Ala Gln Asn
                  85                  90                  95    
 Pro Val Leu Arg Glu Val Val Asp Ile Leu Thr Glu Gln Leu Arg Asp
             100                 105                 110        
 Ile Gln Leu Glu Asn Tyr Thr Pro Lys Glu Pro Leu Thr Leu Gln Ala
         115                 120                 125            
 Arg Met Ser Cys Glu Gln Lys Ala Glu Gly His Ser Ser Gly Ser Trp
     130                 135                 140                
 Gln Phe Ser Phe Asp Gly Gln Ile Phe Leu Leu Phe Asp Ser Glu Lys
 145                 150                 155                 160
 Arg Met Trp Thr Thr Val His Pro Gly Ala Arg Lys Met Lys Glu Lys
                 165                 170                 175    
 Trp Glu Asn Asp Lys Val Val Ala Met Ser Phe His Tyr Phe Ser Met
             180                 185                 190        
 Gly Asp Cys Ile Gly Trp Leu Glu Asp Phe Leu Met Gly Met Asp Ser
         195                 200                 205            
 Thr Leu Glu Pro Ser Ala Gly Ala Pro Leu Ala Met Ser Ser Gly Thr
     210                 215                 220                
 Thr Gln Leu Arg Ala Thr Ala Thr Thr Leu Ile Leu Cys Cys Leu Leu
 225                 230                 235                 240
 Ile Leu Leu Pro Cys Phe Ile Leu Pro Gly Ile
                 245                 250    



      <210> 2597
      <211> 166
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(166)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2597
 Ile Glu Leu Arg Ala Val Ala Gln Gly Ile Ala Gln Ser Leu Gly Gln
   1               5                  10                  15    
 Leu Leu Phe Thr Gln Cys Pro Leu Glu Lys Lys Asp Leu Glu Gly Leu
              20                  25                  30        
 Phe Leu Gln Asn Asn Lys Glu Gly Val Gln Lys Gly Arg Asp Glu Pro
          35                  40                  45            
 Leu Pro Pro Leu Pro Xaa Ala Thr Ala Leu Ser Ser Ile Gln Ala Gly
      50                  55                  60                
 Ile Gln Gln Ala Arg Xaa Glu Gly Asp Leu Glu Ala Trp Gln Phe Pro
  65                  70                  75                  80
 Val Arg Ile His Pro Pro Asp Gln Gln Gly Asn Ile Ile Val Thr Phe
                  85                  90                  95    
 Glu Pro Phe Pro Phe Lys Leu Phe Lys Glu Phe Lys Gln Ala Val Asn
             100                 105                 110        
 Gln Tyr Gly Pro Gly Ser Pro Phe Val Met Gly Leu Leu Lys Asn Val
         115                 120                 125            
 Ala Val Ser Ser Trp Met Ile Pro Thr Asp Trp Asp Ala Leu Thr Arg
     130                 135                 140                
 Ala Cys Leu Thr Pro Ala Gln Phe Leu Gln Phe Lys Thr Trp Trp Ala
 145                 150                 155                 160
 Asp Glu Ala Gly Arg Val
                 165    



      <210> 2598
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2598
 Ala Val Phe Thr Phe His Asn His Gly Arg Thr Ala Asn Leu Tyr Ser
   1               5                  10                  15    
 Leu His Ser Trp Leu Gly Ile Thr Thr Val Phe Leu Phe Ala Cys Gln
              20                  25                  30        
 Arg Phe Leu Gly Phe Ala Val Phe Leu Leu Pro Trp Ala Ser Met Trp
          35                  40                  45            
 Leu Arg Ser Leu Leu Lys Pro Ile His Val Phe Phe Gly Ala Ala Ile
      50                  55                  60                
 Leu Ser Leu Ser Ile Ala Ser Val Ile Ser Gly Ile Asn Glu Lys Leu
  65                  70                  75                  80
 Phe Phe Ser Leu Lys Asn Thr Thr Arg Pro Tyr His Ser Leu Pro Ser
                  85                  90                  95    
 Glu Ala Val Phe Ala Asn Ser Thr Gly Met Leu Val Val Ala Phe Gly
             100                 105                 110        
 Leu Leu Val Leu Tyr Ile Leu Leu Ala Ser Ser Trp Lys Arg Pro
         115                 120                 125        



      <210> 2599
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2599
 Cys Ser Thr Met Asn Pro Ser Glu Met Gln Arg Ile Ala Pro Pro Arg
   1               5                  10                  15    
 Arg Gln Arg His Arg Ser Arg Ala Pro Ser Ala His Lys Met Asn Arg
              20                  25                  30        
 Met Val Met Ser Glu Glu Gln Met Lys Leu Pro Ser Thr Lys Lys Ala
          35                  40                  45            
 Glu Pro Pro Thr Trp Ala Gln Leu Lys Lys Leu Thr Gln Leu Ala Lys
      50                  55                  60                
 Lys Lys Leu Glu Asn Thr Lys Val Thr Gln Thr Pro Glu Asn Met Leu
  65                  70                  75                  80
 Leu Ala Ala Leu Lys Thr Val Ser Thr Val Ser Ala Gly Val Pro Ser
                  85                  90                  95    
 Ser Ser Glu Glu Ser Asp His Arg Glu Arg Ala Met Met Thr Thr Val
             100                 105                 110        
 Val Leu Ser Lys Arg Arg Gly Lys Cys Gly Glu Lys Lys Glu Ile Ser
         115                 120                 125            
 Asp Cys Tyr Cys Val Tyr Val Glu Arg Ser
     130                 135            



      <210> 2600
      <211> 312
      <212> PRT
      <213> Homo sapiens


      <400> 2600
 Met Ala Leu Arg Leu Val Ile Pro Ala Leu Trp Glu Ala Glu Leu Val
   1               5                  10                  15    
 Gly Ala Leu Met Leu Ala Ala Leu Ser His Leu His Arg Phe Leu Leu
              20                  25                  30        
 Ser Met Trp Val Leu Pro Pro Gly Thr Phe Thr Asp Ala Phe Pro Gly
          35                  40                  45            
 Leu Leu Phe His Phe Pro Arg Arg Ser Gln Lys Asp Cys Leu Leu Gly
      50                  55                  60                
 Leu Ser Lys Ser Asp Gln Arg Ala Met Ala Cys Tyr Phe Gly Ile Leu
  65                  70                  75                  80
 Leu Ile Val Ser Ala Thr Leu Cys Phe Gly Met Asn Tyr Tyr Leu Asp
                  85                  90                  95    
 Glu Phe Ala Asn Leu Leu Asp Glu Leu Leu Met Lys Ile Asn Gly Leu
             100                 105                 110        
 Ser Asp Ser Leu Gln Leu Pro Leu Leu Glu Lys Thr Ser Asn Asn Thr
         115                 120                 125            
 Gly Glu Ala Arg Thr Glu Glu Ser Pro Leu Val Asp Ile Ser Ser Tyr
     130                 135                 140                
 Gln Ala Ala Glu Met Val Met Met Ala Arg Thr Leu Ala Thr Cys Leu
 145                 150                 155                 160
 Gln His Ala Gln Gly Leu Gly Phe Glu Ala Cys Leu Pro Ile Leu Ser
                 165                 170                 175    
 Ala Pro His Ala Leu Ser His Trp Thr Leu Thr Thr Cys Leu Trp Gln
             180                 185                 190        
 Leu Gly Phe Met Ser Ala Val Leu Ile Leu Lys Tyr Thr Arg Ala Leu
         195                 200                 205            
 Leu Ala Gln Gly Gln Phe Ser Gly Pro Phe Val Ile Asp Lys Gly Val
     210                 215                 220                
 Arg Leu Glu Leu Ile Gly Leu Ile Ser Arg Val Trp Glu Val Ser Glu
 225                 230                 235                 240
 Gln Glu Asn Ser Lys Glu Glu Val Tyr Arg His Glu Glu Gly Ile Thr
                 245                 250                 255    
 Val Ile Ser Asp Leu Leu Leu Gly Arg Gln Trp Gln Gln Gly His Lys
             260                 265                 270        
 Gly Ile Cys Leu Gln Leu Met Leu Pro Phe Ser Arg Gly Lys His Arg
         275                 280                 285            
 Thr Ser Gly Ala Phe Leu Met Phe Ser Leu Glu Leu Phe Thr Val Ala
     290                 295                 300                
 Gln Leu Val Pro Ile Ser Gly Ser
 305                 310        



      <210> 2601
      <211> 232
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(232)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2601
 Val Leu Asn Pro Leu Gly Lys Pro Xaa His Asp Thr Pro Ala Trp His
   1               5                  10                  15    
 Glu Glu Gly Tyr Pro Phe Pro Thr Ala Pro Pro Val Asp Pro Phe Ala
              20                  25                  30        
 Lys Ile Lys Val Asp Asp Cys Gly Lys Thr Lys Gly Cys Phe Arg Tyr
          35                  40                  45            
 Gly Lys Pro Gly Cys Asn Ala Glu Thr Cys Asp Tyr Phe Leu Ser Tyr
      50                  55                  60                
 Arg Met Ile Gly Ala Asp Val Glu Phe Glu Leu Ser Ala Asp Thr Asp
  65                  70                  75                  80
 Gly Trp Val Ala Val Gly Phe Ser Ser Asp Lys Lys Met Gly Gly Asp
                  85                  90                  95    
 Asp Val Met Ala Cys Val His Asp Asp Asn Gly Arg Val Arg Ile Gln
             100                 105                 110        
 His Phe Tyr Asn Val Gly Gln Trp Ala Lys Glu Ile Gln Arg Asn Pro
         115                 120                 125            
 Ala Arg Asp Glu Glu Gly Val Phe Glu Asn Asn Arg Val Thr Cys Arg
     130                 135                 140                
 Phe Lys Arg Pro Val Asn Val Pro Arg Asp Glu Thr Ile Val Asp Leu
 145                 150                 155                 160
 His Leu Ser Trp Tyr Tyr Leu Phe Ala Trp Gly Pro Ala Ile Gln Gly
                 165                 170                 175    
 Ser Ile Thr Arg His Asp Ile Asp Ser Pro Pro Ala Ser Glu Arg Val
             180                 185                 190        
 Val Ser Ile Tyr Lys Tyr Glu Asp Ile Phe Met Pro Ser Ala Ala Tyr
         195                 200                 205            
 Gln Thr Phe Ser Ser Pro Phe Cys Leu Leu Leu Ile Val Ala Leu Thr
     210                 215                 220                
 Phe Tyr Leu Leu Met Gly Thr Pro
 225                 230        



      <210> 2602
      <211> 105
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(105)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2602
 Phe Tyr Leu Phe Ile Leu Phe Leu Phe Phe Val Phe Leu Val Glu Thr
   1               5                  10                  15    
 Gly Phe His His Val Gly Gln Ala Gly Phe Glu Leu Leu Thr Ser Ser
              20                  25                  30        
 Asp Pro Ser Ala Leu Ala Ser Gln Ser Ala Arg Ile Thr Gly Met Ser
          35                  40                  45            
 His His Ala Trp Pro Asn Phe Cys Leu Leu Ser Arg Asp Gln Val Ser
      50                  55                  60                
 Pro Cys Trp Pro Gly Trp Ser Xaa Thr Pro Asp Leu Arg Xaa Ser Thr
  65                  70                  75                  80
 Phe Leu Gly Leu Pro Lys Cys Xaa Leu Gln Ala Xaa Ala Thr Val Pro
                  85                  90                  95    
 Ser Ala Gly Glu Pro Gln Cys Gly Gln
             100                 105



      <210> 2603
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 2603
 Met Gly Leu Gly Ala Arg Gly Ala Trp Ala Ala Leu Leu Leu Gly Thr
   1               5                  10                  15    
 Leu Gln Val Leu Ala Leu Leu Gly Ala Ala His Glu Ser Ala Ala Met
              20                  25                  30        
 Ala Ala Ser Ala Asn Ile Glu Asn Ser Gly Leu Pro His Asn Ser Ser
          35                  40                  45            
 Ala Asn Ser Thr Glu Thr Leu Gln His Val Pro Ser Asp His Thr Asn
      50                  55                  60                
 Glu Thr Ser Asn Ser Thr Val Lys Pro Pro Thr Ser Val Ala Ser Asp
  65                  70                  75                  80
 Ser Ser Asn Thr Thr Val Thr Thr Met Lys Pro Thr Ala Ala Ser Asn
                  85                  90                  95    
 Thr Thr Thr Pro Gly Met Val Ser Thr Asn Met Thr Ser Thr Thr Leu
             100                 105                 110        
 Lys Ser Thr Pro Lys Thr Thr Ser Val Ser Gln Asn Thr Ser Gln Ile
         115                 120                 125            
 Ser Thr Ser Thr Met Thr Val Thr His Asn Ser Ser Val Thr Ser Ala
     130                 135                 140                
 Ala Ser Ser Val Thr Ile Thr Thr Thr Met His Ser Glu Ala Lys Lys
 145                 150                 155                 160
 Gly Ser Lys Phe Asp Thr Gly Ser Phe Val Gly Gly Ile Val Leu Thr
                 165                 170                 175    
 Leu Gly Val Leu Ser Ile Leu Tyr Ile Gly Cys Lys Met Tyr Tyr Ser
             180                 185                 190        
 Arg Arg Gly Ile Arg Tyr Arg Thr Ile Asp Glu His Asp Ala Ile Ile
         195                 200                 205            





      <210> 2604
      <211> 109
      <212> PRT
      <213> Homo sapiens


      <400> 2604
 Trp Val Phe Ser Ser Pro Ile Thr Ala Arg Asp Ala Leu Gly Ile Lys
   1               5                  10                  15    
 His Thr Met Val Lys Ile Arg Pro Leu Ser Gln Ala Thr Arg Ala Ala
              20                  25                  30        
 Lys Ala Lys Ala Arg Ala Tyr Ala Glu Phe Leu Gln Pro Ala Lys Glu
          35                  40                  45            
 Arg Pro Glu Thr Ser Ala Ala Leu Ala Arg Arg Leu Val Ile Ser Ala
      50                  55                  60                
 Leu Gly Val Arg Ser Lys Gln Ser Lys Thr Glu Arg Glu Ala Glu Leu
  65                  70                  75                  80
 Lys Lys Leu Gln Glu Ala Arg Glu Arg Lys Arg Leu Glu Ala Lys Gln
                  85                  90                  95    
 Arg Glu Asp Ile Trp Glu Gly Arg Asp Gln Ser Thr Val
             100                 105                



      <210> 2605
      <211> 30
      <212> PRT
      <213> Homo sapiens


      <400> 2605
 Cys Cys Cys Cys Cys Cys Cys Leu Cys Phe Gly Ile His Ser Ser Lys
   1               5                  10                  15    
 Gly Thr His Ser Ala Asn Ser Asp Lys Trp Pro Phe Asp Pro
              20                  25                  30



      <210> 2606
      <211> 172
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(172)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2606
 Ser Cys Tyr Val Cys Gly Gly Thr Val Thr Gly Asp Gln Trp Pro Xaa
   1               5                  10                  15    
 Glu Ala Arg Glu Leu Val Pro Thr Asp Pro Val Pro Asp Glu Phe Pro
              20                  25                  30        
 Ala Gln Lys Asn His Pro Asp Asn Phe Xaa Val Leu Lys Val Ser Ile
          35                  40                  45            
 Ile Arg Gln Tyr Cys Thr Ala Ile Glu Gly Lys Gln Phe Thr His Ser
      50                  55                  60                
 Ile Gly Arg Leu Ser Cys Leu Arg Gln Lys Leu Tyr Asn Gly Thr Thr
  65                  70                  75                  80
 Lys Thr Val Thr Trp Trp Asn Ser Asn Tyr Thr Glu Arg Asn Pro Phe
                  85                  90                  95    
 Ser Lys Phe Pro Lys Leu Gln Thr Val Trp Ala His Pro Glu Phe His
             100                 105                 110        
 Trp Asp Trp Met Ala Pro Thr Arg Leu Tyr Trp Ile Cys Gly His Arg
         115                 120                 125            
 Ala Tyr Ala Lys Leu Pro Asp Gln Trp Thr Gly Ser Cys Val Ile Ser
     130                 135                 140                
 Thr Ile Lys Pro Ser Phe Phe Leu Leu Pro Ile Lys Thr Gly Glu Leu
 145                 150                 155                 160
 Leu Gly Phe Pro Val Tyr Ala Ser His Glu Lys Arg
                 165                 170        



      <210> 2607
      <211> 135
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(135)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2607
 Phe Leu Val Glu Thr Glu Phe Cys Tyr Val Gly Gln Ala Gly Leu Glu
   1               5                  10                  15    
 Leu Leu Thr Ser Arg Asp Pro Pro Ala Ser Ala Ser Lys Gly Ala Gly
              20                  25                  30        
 Met Thr Gly Val Ser His Gln Val Gln Pro Gln Xaa Xaa Ser Xaa Leu
          35                  40                  45            
 Trp Thr Xaa Pro Ser Ser Val Glu Ala Gly Thr Ser Phe Gly Leu Ser
      50                  55                  60                
 Phe Leu Ser Ser Ser Trp Ala Leu Ser Ala Gln Glu Gly Cys Leu Ala
  65                  70                  75                  80
 Val Pro Ser Ser Gly Ser Arg Gly Leu Leu Val Gly Ala Leu Leu Leu
                  85                  90                  95    
 Trp Thr Lys Pro Ser Pro Gln Leu Ser Pro Val Pro Ala Ser Gln Arg
             100                 105                 110        
 Leu Ser Ser Leu Ser Leu Met Pro Pro Leu Pro Gln Pro Gln His Leu
         115                 120                 125            
 Thr His Thr Ser Ile Glu Thr
     130                 135



      <210> 2608
      <211> 741
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(741)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2608
 Phe Phe Phe Asn Lys Asn Leu Leu Phe Ile Gln Lys Leu Thr Pro Gly
   1               5                  10                  15    
 Val Phe Ser Pro Ile Phe Lys Lys Lys Lys Lys Arg Gly Gly Gln Gly
              20                  25                  30        
 Phe Pro Ser Gln Cys Pro Xaa Val Asn Ser Leu Ala Ile Gln Gly Trp
          35                  40                  45            
 Pro Ser Arg Gly Val Ser Gly Lys Arg Cys Gln Lys Cys Gly Gly Pro
      50                  55                  60                
 Gly Pro Leu Arg Thr His Ser Pro Leu Leu Ala Ser Pro Leu Gln Pro
  65                  70                  75                  80
 Pro Ser Trp Thr Thr Arg Pro Val Gly Leu Gln Pro Pro Gly Ala Leu
                  85                  90                  95    
 Gly Leu Thr Thr Thr Arg Gly Arg Ala Ala Leu Pro Xaa Leu Pro Xaa
             100                 105                 110        
 Asn Xaa Met Leu Lys Pro Arg Trp Glu Gln Gly Asp Phe Pro Pro Gly
         115                 120                 125            
 Gly Trp Ala Met Glu Ala Phe Ser Arg Asp Ser Leu Pro Leu Gln Glu
     130                 135                 140                
 Gly Ile Pro Gly Ile Pro Thr Ser Pro Pro Thr Pro Ser Glu Lys Asn
 145                 150                 155                 160
 Lys Val Pro Glu Thr Pro Gly Ala Leu Val Xaa Glu Thr Gly Cys Gln
                 165                 170                 175    
 Thr Glu Lys His Phe Arg Gly Gly Asp Val Ser Thr Glu Gly Asp Thr
             180                 185                 190        
 Tyr Ala Cys Leu Asp Val Ile Leu Asn Val Ala Cys Leu Asp His Gly
         195                 200                 205            
 Lys Ser Glu His Ser Pro Lys Ser Pro Ser Thr Gln Ser Glu Glu Gln
     210                 215                 220                
 Thr Leu Arg Gly Arg Gly Gln Ala Val Ala Asp Trp Pro Pro Gly Ala
 225                 230                 235                 240
 Gly Ala Cys Pro Gly Pro Ser Ala Arg Leu Cys Arg Gly Thr Met Gly
                 245                 250                 255    
 Met Pro Ser Ala Ser Glu His Leu Lys Arg Ala Ala Leu Gly Gly Lys
             260                 265                 270        
 Pro Pro Leu Trp Arg Gly Ala Arg Ala Ala Gln Glu Ala Pro Gly Ser
         275                 280                 285            
 Gly Phe Cys Gly Ile Thr Ala Ala Arg Gly Leu Gly Arg Gly Gly Gly
     290                 295                 300                
 Arg Asp Arg Ser Leu Pro Gly Lys Leu Xaa Xaa Lys Trp Pro Val Ser
 305                 310                 315                 320
 Ser Thr Pro Pro Gly Pro Gly Arg Ala Ala Leu Pro Ala Ala Leu Gly
                 325                 330                 335    
 Trp Pro Gly Cys Gly Pro Thr Gly Met Pro Gly Leu Arg Ser Ala Ser
             340                 345                 350        
 Ile Pro Ser Ala Lys Ala Arg Ser His Thr Cys Gly Phe Lys Pro Lys
         355                 360                 365            
 Gly Leu Lys Gly Arg Thr Met Glu Glu Gly Gln Thr His Arg Arg Gly
     370                 375                 380                
 Pro His Ala Xaa Ala Gln Thr Pro Ser Ala Thr Gly Gln Val Val Gln
 385                 390                 395                 400
 Gln Cys Pro Val Pro Leu Asp Gln Arg Gly Lys Ser Ser Leu Arg Gln
                 405                 410                 415    
 Arg Pro Lys Glu Ser Asn Leu Thr Gly Lys Asp Leu Pro His Pro Leu
             420                 425                 430        
 Ser Pro Lys Pro Pro Cys Arg Ser Leu Pro Gln Thr Pro Gly Gln Ser
         435                 440                 445            
 Pro Ala Glu Lys Leu Gln Pro Leu Val Leu Ser Pro Arg Ser Pro Gly
     450                 455                 460                
 Pro Ala Ala Glu Gln Gly Ala Asp Trp Gln Gly Pro Gln Arg Ile His
 465                 470                 475                 480
 Pro Ser Lys Trp Pro Val Lys Val Glu Pro Leu Thr Pro Ser Leu Gln
                 485                 490                 495    
 Asp Val Gly Gly Gly Gly Gly Val Thr Val Gly Pro Ala Cys Ser Pro
             500                 505                 510        
 Arg Gly Leu Pro Met Asn Ala Ser Gly Gly Thr Leu Gly Leu Ala Glu
         515                 520                 525            
 Cys Ser Ser Gln Gly Glu Gln Pro Arg Ser Pro Thr Arg Gln Arg His
     530                 535                 540                
 His Gly Arg Gly Leu Pro Arg Ala Gly Gly Leu Leu Ala Glu Gly Gly
 545                 550                 555                 560
 Asn Arg Gly Pro Lys Cys Pro Pro Leu Lys His Gly Leu Met Gly Cys
                 565                 570                 575    
 Xaa Leu Cys Lys Ala Ala Ala Arg Ile Leu Asp Pro Gly Leu Ala Leu
             580                 585                 590        
 Thr Val Trp Glu Ala Ala Ser His Pro Ser Leu Pro Cys Ala Arg Thr
         595                 600                 605            
 Pro Ser Gly Ser Gln Arg Ala Leu Lys Gly Leu Gly Gly Thr Arg Lys
     610                 615                 620                
 Cys Cys Gly Lys Gly Gln Gly Val Pro His Asp Asn Ser Ser Ala Gly
 625                 630                 635                 640
 Thr Asp Pro Thr His Gln Gln Pro Arg Asn Arg Gly Cys Ala Gly Asp
                 645                 650                 655    
 Ser Asp Ser Pro Ser Gly Cys Trp Gly Gln Ala Asn Leu Thr Thr Ala
             660                 665                 670        
 Ser Pro Ala Thr Gly Asn Xaa Thr Pro Gly Leu Glu Xaa His Asp Val
         675                 680                 685            
 Gly Met Glu Lys Gly Leu Gln Asp Gln Gln Pro Gly Pro Pro Arg Ser
     690                 695                 700                
 Ala Asp Gly Ala Thr Glu Thr Gln Arg Gly Gln Glu Ala Ala His Asn
 705                 710                 715                 720
 Gln Arg Ala Arg Gly Arg Thr Leu Gly Ser Tyr Leu Trp Ser Arg Val
                 725                 730                 735    
 Gly Ser His Ser Trp
             740    



      <210> 2609
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 2609
 Met Asp Gly Gln Ala Arg Trp Leu Thr Pro Val Ile Pro Ala Leu Trp
   1               5                  10                  15    
 Glu Ala Glu Val Phe Ile Glu His Met Leu Tyr Ala Leu Asn Ile Leu
              20                  25                  30        
 Arg Thr Val Leu Gly Arg Ala Arg Thr Leu Ser Leu Asn His Arg Cys
          35                  40                  45            
 Arg Leu Leu Leu Leu Ser Leu Leu Val Leu His Cys Val Arg Ser Val
      50                  55                  60                
 Arg Ser Trp Tyr Leu Phe Cys Glu Ala Ala Ala Glu Lys Thr Leu Ala
  65                  70                  75                  80
 Phe Ala Met Ala Glu Glu Lys Pro Lys Ala Leu Ser Met Gly Gln Ile
                  85                  90                  95    
 Arg Phe Arg Phe Asp Ser Gln Pro Ile Asn Glu Thr Asp Thr Pro Val
             100                 105                 110        
 Gln Val Glu Met Glu Asp Ile Asp Ile Ile Asp Val Phe His Gln Gln
         115                 120                 125            
 Ile Gly Gly Val Tyr
     130            



      <210> 2610
      <211> 547
      <212> PRT
      <213> Homo sapiens


      <400> 2610
 Met Gly Glu Leu His Met Ile Thr Glu Glu Lys His Gln Pro Phe Met
   1               5                  10                  15    
 Asp Thr Gln Thr Ala Ala Lys Gly Thr Leu Leu Glu Ala Gly Pro Gly
              20                  25                  30        
 Leu Asp Pro Val Cys Leu Gly His Ile Lys Lys Val Ile Gln Arg Lys
          35                  40                  45            
 Phe Trp Arg Tyr Ser Ala Pro Gly Thr Val Pro Thr Thr Ser Ala Ile
      50                  55                  60                
 Pro Gly Glu Thr Glu Trp Gly Arg Leu Pro Gln Trp Ser Thr Ala Trp
  65                  70                  75                  80
 Ser Glu Thr Ala Gln His Gly Trp Pro Ala Ala Arg Gln Ser Arg Ile
                  85                  90                  95    
 Thr Val Leu His Gln Gln Pro Gln Cys Asp Pro Gly Pro Glu Val Thr
             100                 105                 110        
 Ser Glu Gln Leu Pro Gly Val Ile Asn Met Leu Thr Leu Lys Tyr Ile
         115                 120                 125            
 Lys Val Ala Ala His Pro His Gly Ser Trp Asn Thr Arg Val Pro Cys
     130                 135                 140                
 Leu Val Ala Val Leu Leu Thr Pro Thr Arg Leu Ser Tyr Tyr Ile Ser
 145                 150                 155                 160
 Glu Ile Gln Thr Thr Phe Arg Glu Tyr Tyr Lys His Leu Tyr Glu Asn
                 165                 170                 175    
 Lys Leu Glu Asn Leu Glu Glu Met Asp Lys Phe Leu Asp Thr Tyr Thr
             180                 185                 190        
 Leu Pro Arg Leu Asn Gln Glu Glu Val Glu Ser Leu Asn Arg Pro Met
         195                 200                 205            
 Thr Ser Ser Glu Ile Glu Ala Val Ile Asn Ser Leu Pro Thr Lys Lys
     210                 215                 220                
 Ser Pro Gly Pro Asp Gly Phe Thr Ala Glu Phe Tyr Gln Arg Tyr Glu
 225                 230                 235                 240
 Glu Glu Leu Val Pro Phe Leu Leu Arg Leu Phe Gln Thr Ile Glu Lys
                 245                 250                 255    
 Glu Gly Ile Leu Pro Asn Ser Phe Tyr Glu Ala Ser Ile Ile Leu Ile
             260                 265                 270        
 Pro Lys Pro Gly Arg Asp Thr Thr Lys Asn Glu Asn Phe Arg Pro Ile
         275                 280                 285            
 Ser Leu Met Asn Ile Asp Ala Lys Thr Leu Asn Lys Ile Met Ala Asn
     290                 295                 300                
 Arg Ile Gln Gln His Ser Lys Lys Leu Ile His His Asn Gln Val Gly
 305                 310                 315                 320
 Phe Ile Ser Gly Met Gln Gly Trp Phe Asn Ile Cys Lys Ser Ile Asn
                 325                 330                 335    
 Ile Ile His His Ile Asn Arg Thr Asn Asp Lys Asn His Met Ile Ile
             340                 345                 350        
 Ser Ile Asp Ala Glu Lys Ala Phe Asp Lys Ile Gln His Pro Phe Met
         355                 360                 365            
 Leu Lys Ala Leu Asn Lys Leu Gly Ile Asp Gly Thr His Leu Lys Ile
     370                 375                 380                
 Ile Arg Ala Ile Phe Asp Lys Pro Thr Ala Asn Ile Ile Leu Asn Gly
 385                 390                 395                 400
 Gln Lys Leu Glu Ala Phe Leu Leu Lys Thr Asp Thr Arg Gln Gly Cys
                 405                 410                 415    
 Pro Leu Ser Pro Leu Leu Phe Asn Val Val Leu Glu Val Leu Ala Arg
             420                 425                 430        
 Ala Ile Arg Gln Glu Lys Glu Ile Pro Ala Pro Ala Asp Thr Ser Ser
         435                 440                 445            
 Leu Ile Ala His His Pro Ser Pro Ser Tyr Gln Pro Trp Thr Pro Val
     450                 455                 460                
 Thr Arg Thr Ser His Ser Thr Pro Thr Ile Thr Cys Tyr Pro Cys Leu
 465                 470                 475                 480
 Glu Cys Thr Pro Ala Lys Trp Leu Thr Ser Val Ser Thr Met Gly Gly
                 485                 490                 495    
 Gly Leu Leu Ser Val Pro Gln Gly Thr Val Arg Val Ser Ala Leu Asn
             500                 505                 510        
 Tyr Cys Phe Ile Pro Gln Leu Gly Gly Gly Pro Leu Met Ala Ser Ser
         515                 520                 525            
 Ala Ser Ser Asp Tyr Val Pro Glu Ser Asp Glu Ser Glu Pro Leu Phe
     530                 535                 540                
 Thr Phe Glu
 545        



      <210> 2611
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2611
 Leu Leu Ser Pro Ser His Pro Leu Thr Ala Pro Pro Pro Arg Pro Pro
   1               5                  10                  15    
 Arg Pro Pro Pro Thr Arg Ala Pro Gly Ala Cys Ala Ser Ser Met Gly
              20                  25                  30        
 Pro Pro Thr Ser Lys Phe Pro Lys Asp Leu Thr Leu Pro Gly Asp Ala
          35                  40                  45            
 Ala Leu Gly Cys Gly Thr Pro Ala Thr Gly Gly Glu Gly Ala Ser Ser
      50                  55                  60                
 Arg Ala Arg Ser Glu Thr Gln Arg Ala Arg Ala Pro Thr Pro Gly Arg
  65                  70                  75                  80
 Ser Trp Gly Arg Ala Gly Ser Ala
                  85            



      <210> 2612
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2612
 Pro Ile Cys Leu Phe Ser Arg Pro Thr Leu Arg Pro Ser Arg Ser Lys
   1               5                  10                  15    
 Val Ser Leu Ile Glu Gly Arg Gly Ala Asn Met Ala Ala Arg Trp Arg
              20                  25                  30        
 Phe Trp Cys Val Ser Val Thr Met Val Val Ala Leu Leu Ile Val Cys
          35                  40                  45            
 Asp Val Pro Ser Ala Ser Ala Gln Arg Lys Lys Glu Met Val Leu Ser
      50                  55                  60                
 Glu Lys Val Ser Gln Leu Met Glu Trp Thr Asn Lys Arg Pro Val Ile
  65                  70                  75                  80
 Arg Met Asn Gly Asp Lys Phe Arg Arg Leu Val Lys Ala Pro Pro Arg
                  85                  90                  95    
 Asn Tyr Ser Val Ile Val Met Phe Thr Ala Leu Gln Leu His Arg Gln
             100                 105                 110        
 Cys Val Val Cys Lys Tyr Glu Leu Gln Leu Arg Phe Lys Ile Lys
         115                 120                 125        



      <210> 2613
      <211> 208
      <212> PRT
      <213> Homo sapiens


      <400> 2613
 Ser Arg Val Glu Asp Phe Val Leu His Leu Leu Arg Ala Leu Ala Gln
   1               5                  10                  15    
 Asp Asp Val Val Pro Tyr Phe Lys Thr Glu Pro Gly Leu Pro Gln Ile
              20                  25                  30        
 His Leu Glu Gly Asn Arg Leu Val Leu Thr Cys Leu Ala Glu Gly Ser
          35                  40                  45            
 Trp Pro Leu Glu Phe Lys Trp Met Arg Asp Asp Ser Glu Leu Thr Thr
      50                  55                  60                
 Tyr Ser Ser Glu Tyr Lys Tyr Ile Ile Pro Ser Leu Gln Lys Leu Asp
  65                  70                  75                  80
 Ala Gly Phe Tyr Arg Cys Val Val Arg Asn Arg Met Gly Ala Leu Leu
                  85                  90                  95    
 Gln Arg Lys Ser Glu Val Gln Val Ala Tyr Met Gly Ser Phe Met Asp
             100                 105                 110        
 Thr Asp Gln Arg Lys Thr Val Ser Gln Gly Arg Ala Ala Ile Leu Asn
         115                 120                 125            
 Leu Leu Pro Ile Thr Ser Tyr Pro Arg Pro Gln Val Thr Trp Phe Arg
     130                 135                 140                
 Glu Gly His Lys Ile Ile Pro Ser Asn Arg Ile Ala Ile Thr Leu Glu
 145                 150                 155                 160
 Asn Gln Leu Val Ile Leu Ala Thr Thr Thr Ser Asp Ala Gly Ala Tyr
                 165                 170                 175    
 Tyr Val Gln Ala Val Asn Glu Lys Asn Gly Glu Asn Lys Thr Ser Pro
             180                 185                 190        
 Phe Ile His Leu Ser Ile Ala Ser Phe Cys Gly Asn Thr Thr Gln Asp
         195                 200                 205            





      <210> 2614
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 2614
 Ser Asn Leu Cys Leu Gly Asn Ser Trp Arg Trp Arg Trp Ala Lys Ser
   1               5                  10                  15    
 Arg His His Cys Ile Pro Thr Val Thr Leu Ser Lys Arg Ser Gly Asp
              20                  25                  30        
 Ile Arg Gly Ser His Phe Ser Ser Pro Gln Arg Gln Arg Ser Gln Arg
          35                  40                  45            
 Val Pro Gly Lys Glu Thr Ala Arg Val Leu Arg Ala Gly Lys Gln Gly
      50                  55                  60                
 Arg Gly Gln Ile Pro Ile Pro Cys Pro Trp Pro Pro Pro Pro Pro Pro
  65                  70                  75                  80
 Pro Pro Pro Gly Ser Pro Gly Pro Gly Cys Arg Gln Phe His Gln Ser
                  85                  90                  95    
 Leu Glu Ala Lys Ala Arg His Pro Ala Ser Val Arg Glu Met Arg Gly
             100                 105                 110        
 Lys Val Lys Met Arg Arg Ala Leu Arg Arg Ala Pro Ala Ser Thr Arg
         115                 120                 125            
 Ala Ser Ser Arg Gln Pro Asn Pro Lys
     130                 135        



      <210> 2615
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 2615
 Thr Gly Pro Thr Ile Lys Asn Met Asp Gly Thr Phe Asn Val Thr Ser
   1               5                  10                  15    
 Cys Leu Lys Leu Asn Ser Ser Gln Glu Asp Pro Gly Thr Val Tyr Gln
              20                  25                  30        
 Cys Val Val Arg His Ala Ser Leu His Thr Pro Leu Arg Ser Asn Phe
          35                  40                  45            
 Thr Leu Thr Ala Ala Arg His Ser Leu Ser Glu Thr Glu Lys Thr Asp
      50                  55                  60                
 Asn Phe Ser Ile His Trp Trp Pro Ile Ser Phe Ile Gly Val Gly Leu
  65                  70                  75                  80
 Val Leu Leu Ile Val Leu Ile Pro Trp Lys Lys Ile Cys Asn Lys Ser
                  85                  90                  95    
 Ser Ser Ala Tyr Thr Pro Leu Lys Cys Ile Leu Lys His Trp Asn Ser
             100                 105                 110        
 Phe Asp Thr Gln Thr Leu Lys Lys Glu His Leu Ile Phe Phe Cys Thr
         115                 120                 125            
 Arg Ala Trp Pro Ser Tyr Gln Leu Gln Asp Gly Glu Ala Trp Pro Pro
     130                 135                 140                
 Glu Gly Ser Val Asn Ile Asn Thr Tyr Ser Thr Thr Val
 145                 150                 155        



      <210> 2616
      <211> 661
      <212> PRT
      <213> Homo sapiens


      <400> 2616
 Ser Leu Ser Gly Phe Thr Arg Glu Ala Ser Phe Glu Met Ala Ala Gln
   1               5                  10                  15    
 Arg Ile Arg Ala Ala Asn Ser Asn Gly Leu Pro Arg Cys Lys Ser Glu
              20                  25                  30        
 Gly Thr Leu Ile Asp Leu Ser Glu Gly Phe Ser Glu Thr Ser Phe Asn
          35                  40                  45            
 Asp Ile Lys Val Pro Ser Pro Ser Ala Leu Leu Val Asp Asn Pro Thr
      50                  55                  60                
 Pro Phe Gly Asn Ala Lys Glu Val Ile Ala Ile Lys Asp Tyr Cys Pro
  65                  70                  75                  80
 Thr Asn Phe Thr Thr Leu Lys Phe Ser Lys Gly Asp His Leu Tyr Val
                  85                  90                  95    
 Leu Asp Thr Ser Gly Gly Glu Trp Trp Tyr Ala His Asn Thr Thr Glu
             100                 105                 110        
 Met Gly Tyr Ile Pro Ser Ser Tyr Val Gln Pro Leu Asn Tyr Arg Asn
         115                 120                 125            
 Ser Thr Leu Ser Asp Ser Gly Met Ile Asp Asn Leu Pro Asp Ser Pro
     130                 135                 140                
 Asp Glu Val Ala Lys Glu Leu Glu Leu Leu Gly Gly Trp Thr Asp Asp
 145                 150                 155                 160
 Lys Lys Val Pro Gly Arg Met Tyr Ser Asn Asn Pro Phe Trp Asn Gly
                 165                 170                 175    
 Val Gln Thr Asn Pro Phe Leu Asn Gly Asn Val Pro Val Met Pro Ser
             180                 185                 190        
 Leu Asp Glu Leu Asn Pro Lys Ser Thr Val Asp Leu Leu Leu Phe Asp
         195                 200                 205            
 Ala Gly Thr Ser Ser Phe Thr Glu Ser Ser Ser Ala Thr Thr Asn Ser
     210                 215                 220                
 Thr Gly Asn Ile Phe Asp Glu Leu Pro Val Thr Asn Gly Leu His Ala
 225                 230                 235                 240
 Glu Pro Pro Val Arg Arg Asp Asn Pro Phe Phe Arg Ser Lys Arg Ser
                 245                 250                 255    
 Tyr Ser Leu Ser Glu Leu Ser Val Leu Gln Ala Lys Ser Asp Ala Pro
             260                 265                 270        
 Thr Ser Ser Ser Phe Phe Thr Gly Leu Lys Ser Pro Ala Pro Glu Gln
         275                 280                 285            
 Phe Gln Ser Arg Glu Asp Phe Arg Thr Ala Trp Leu Asn His Arg Lys
     290                 295                 300                
 Leu Ala Arg Ser Cys His Asp Leu Asp Leu Leu Gly Gln Ser Pro Gly
 305                 310                 315                 320
 Trp Gly Gln Thr Gln Ala Val Glu Thr Asn Ile Val Cys Lys Leu Asp
                 325                 330                 335    
 Ser Ser Gly Gly Ala Val Gln Leu Pro Asp Thr Ser Ile Ser Ile His
             340                 345                 350        
 Val Pro Glu Gly His Val Ala Pro Gly Glu Thr Gln Gln Ile Ser Met
         355                 360                 365            
 Lys Ala Leu Leu Asp Pro Pro Leu Glu Leu Asn Ser Asp Arg Ser Cys
     370                 375                 380                
 Ser Ile Ser Pro Val Leu Glu Val Lys Leu Ser Asn Leu Glu Val Lys
 385                 390                 395                 400
 Thr Ser Ile Ile Leu Glu Met Lys Val Ser Ala Glu Ile Lys Asn Asp
                 405                 410                 415    
 Leu Phe Ser Lys Ser Thr Val Gly Leu Gln Cys Leu Arg Ser Asp Ser
             420                 425                 430        
 Lys Glu Gly Pro Tyr Val Ser Val Pro Leu Asn Cys Ser Cys Gly Asp
         435                 440                 445            
 Thr Val Gln Ala Gln Leu His Asn Leu Glu Pro Cys Met Tyr Val Ala
     450                 455                 460                
 Val Val Ala His Gly Pro Ser Ile Leu Tyr Pro Ser Thr Val Trp Asp
 465                 470                 475                 480
 Phe Ile Asn Lys Lys Val Thr Val Gly Leu Tyr Gly Pro Lys His Ile
                 485                 490                 495    
 His Pro Ser Phe Lys Thr Val Val Thr Ile Phe Gly His Asp Cys Ala
             500                 505                 510        
 Pro Lys Thr Leu Leu Gly Ser Gly Glu Val Thr Arg Gln Ala Pro Asn
         515                 520                 525            
 Pro Ala Pro Val Ala Leu Gln Leu Pro Gln Asp Leu Lys Val Cys Met
     530                 535                 540                
 Phe Ser Asn Met Thr Asn Tyr Glu Val Lys Ala Ser Glu Gln Ala Lys
 545                 550                 555                 560
 Val Val Arg Gly Phe Gln Leu Lys Leu Gly Lys Val Ser Arg Leu Ile
                 565                 570                 575    
 Phe Pro Ile Thr Ser Gln Asn Pro Asn Glu Leu Ser Asp Phe Thr Leu
             580                 585                 590        
 Arg Val Gln Val Lys Asp Asp Gln Glu Ala Ile Leu Thr Gln Phe Cys
         595                 600                 605            
 Val Gln Thr Pro Gln Pro Pro Pro Lys Ser Ala Ile Lys Pro Ser Gly
     610                 615                 620                
 Gln Arg Arg Phe Leu Lys Lys Asn Glu Val Gly Lys Ile Ile Leu Ser
 625                 630                 635                 640
 Pro Phe Ala Thr Thr Thr Lys Tyr Pro Thr Phe Gln Asp Arg Pro Val
                 645                 650                 655    
 Ser Ser Leu Lys Phe
             660    



      <210> 2617
      <211> 150
      <212> PRT
      <213> Homo sapiens


      <400> 2617
 Met Ser Gly Trp Leu Gly Leu Val Ser Ser Leu His Arg Leu Leu Val
   1               5                  10                  15    
 Ser Pro Cys Pro Gly Arg Thr Val Gly Leu Gln Arg Arg Lys Arg Leu
              20                  25                  30        
 Lys Ser Gly Ser Ser Arg Met Ser Phe Pro Val Thr Arg Arg Pro Arg
          35                  40                  45            
 Glu Gln Thr Pro His Pro Asp Ile Val Ala Ala Ile Pro Ser Gly Thr
      50                  55                  60                
 Asp Asp Phe Gln Gly His Arg Ser Lys Glu Lys Glu Asn Trp Lys Pro
  65                  70                  75                  80
 Met Cys Leu Asn Arg Phe Ile Leu Glu Glu Cys Ile Ala Ala Asp Asp
                  85                  90                  95    
 Phe Arg Ile Arg Gly Leu Glu Pro Asn Pro Gln Tyr Leu Gln Gly Lys
             100                 105                 110        
 Pro Thr Gln Val Ser Glu Ser Leu Arg Leu Leu Arg Asn Asp Thr Gln
         115                 120                 125            
 Asp Pro Asn Ile Lys Thr Arg Tyr Ile Met Asn Leu Ala Lys Thr Ile
     130                 135                 140                
 Gln Arg Ser Pro Asp Lys
 145                 150



      <210> 2618
      <211> 136
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(136)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2618
 Met Ile Ile Ile Pro Lys Asn Leu Asn Met Cys Ala Leu Gln Ser Lys
   1               5                  10                  15    
 Pro Glu Ser Arg Gly Phe Gly Glu Leu Ser Gln Arg Gly Asn Val Lys
              20                  25                  30        
 Phe Asn Val Glu Thr Leu Cys Ser His Gln Lys Lys Ile Ser Arg Leu
          35                  40                  45            
 Ser Ala Ala Ile His Gln Leu Asp Ile Ser Asp Ile Arg Pro Leu Thr
      50                  55                  60                
 Val Leu Leu Thr Leu Cys Ile Thr Leu Ala Leu Leu Met Arg Gly Ala
  65                  70                  75                  80
 Gln Pro Gly Met Asn Ser Gly Lys Ile Pro Tyr Arg Met Phe Ile Pro
                  85                  90                  95    
 Asn Ser His Ser Asp Ser Glu Leu Met Ser Phe Gln Asp Ser Val Arg
             100                 105                 110        
 His Arg Arg Gly Gly Phe Gln Thr Phe Asp Cys Asp Ser Gln Gln Glu
         115                 120                 125            
 Thr Phe Trp Thr Trp Ser Ile Xaa
     130                 135    



      <210> 2619
      <211> 262
      <212> PRT
      <213> Homo sapiens


      <400> 2619
 Met Gly Arg Glu Arg Asp Pro Ser Gly Trp Thr Trp Leu Leu Arg Cys
   1               5                  10                  15    
 Ala Ala Ala Ala Cys Ala Leu Leu Leu Gly Ser Gln Arg Gln Glu Thr
              20                  25                  30        
 Gln Leu Leu Leu Ser Glu His Ser Asp Pro Asp Ile Glu His Arg Val
          35                  40                  45            
 Arg Gly Glu Pro Lys Arg Thr Thr Arg Trp Leu Gly Val Glu Cys Trp
      50                  55                  60                
 Arg Gln Gly Val Ile Asn Ile Glu Thr Lys Ala Gln Glu Gln Leu Gln
  65                  70                  75                  80
 Pro Lys Gly Lys Lys Val Ser Ser Leu Leu Thr Ala Leu Pro Gly Ser
                  85                  90                  95    
 Ile Asp Glu Leu Ser Leu Lys Arg Asp Val Lys Glu Ser Ile Ser Leu
             100                 105                 110        
 Pro Ala Val Pro Phe Gln Ile Glu Leu Leu Leu Ile Ser Lys Ile Asn
         115                 120                 125            
 Met Gln Thr Arg Leu Leu Gln Leu Pro Leu Lys Phe Ala Val Ala Ala
     130                 135                 140                
 Ala Ser Ser Arg Phe Asn Pro Arg Pro Pro Val Ile Gly Gln Leu Leu
 145                 150                 155                 160
 Arg Gly Lys Lys Ser Thr Pro Trp Gln Pro Asp Lys Pro Ile Lys Ser
                 165                 170                 175    
 Pro Ala Gly Val Thr Ala Ala Thr Leu Gln Ala Gly Val Gly Trp Ala
             180                 185                 190        
 Glu Glu Gln Ser Gly His Cys Ala Gln Val His Ser Leu Gly Val Asp
         195                 200                 205            
 Ser Ser Cys Trp Ser Pro Arg Ser Gly Tyr Thr Tyr Val His His Pro
     210                 215                 220                
 Val His Thr Pro Thr Leu Cys Ala Leu Val Gly Ser Gly Gly Glu Arg
 225                 230                 235                 240
 Gly Gly Gly Glu Gly Glu Lys His Ile Gly Leu Glu Glu Gln Glu Pro
                 245                 250                 255    
 Gln Lys Arg Val Leu Asn
             260        



      <210> 2620
      <211> 303
      <212> PRT
      <213> Homo sapiens


      <400> 2620
 Phe Met Thr Asp Val Asn Ser Trp Leu Leu Thr Phe Gly Phe Gln Leu
   1               5                  10                  15    
 His Asn Val Ile Pro Gly Tyr Pro Lys Pro Asp Met Asp Ala Met Glu
              20                  25                  30        
 Pro Ser Tyr Glu Leu Ile His Thr Gln Met Lys Thr Gln Glu Trp Asp
          35                  40                  45            
 Asn Ser Lys Ser Ile Leu Gly Val Gln Cys Glu Val Gln Lys Gln Leu
      50                  55                  60                
 Lys Ala Phe Val Thr Leu Glu Arg Phe Asp Gln Leu Tyr Gly Ser Thr
  65                  70                  75                  80
 Ile Thr Ser Cys Gln Gln Ala Pro Lys Thr Lys Lys Phe Ala Ser Ser
                  85                  90                  95    
 Gly Ser Val Phe Gly Lys Gly Val Lys Phe Ala Leu Lys Asp Gly Arg
             100                 105                 110        
 Val Thr Thr Asp Ile Ile Ser Val Ala Asn Glu Asp Gly Arg Arg Val
         115                 120                 125            
 Ala Ala Ile Leu Asn His Ala His Tyr Leu Glu Asn Leu His Phe Thr
     130                 135                 140                
 Ile Asp Gly Val Asp Thr His Tyr Phe Val Lys Pro Gly Pro Ser Glu
 145                 150                 155                 160
 Gly Asp Leu Ala Ile Leu Gly Leu Ser Gly Gly Arg Arg Thr Leu Glu
                 165                 170                 175    
 Asn Gly Val Asn Val Thr Val Ser Gln Ile Asn Thr Val Leu Asn Gly
             180                 185                 190        
 Arg Thr Arg Arg Tyr Thr Asp Ile Gln Leu Gln Tyr Gly Ala Leu Cys
         195                 200                 205            
 Leu Asn Thr Arg Tyr Gly Thr Thr Leu Asp Glu Glu Lys Ala Arg Val
     210                 215                 220                
 Leu Glu Leu Ser Arg Gln Arg Ala Val Arg Gln Ala Trp Ala Arg Glu
 225                 230                 235                 240
 Gln Gln Arg Leu Arg Glu Gly Glu Glu Gly Leu Arg Ala Trp Thr Glu
                 245                 250                 255    
 Gly Glu Lys Gln Gln Val Leu Ser Thr Gly Arg Val Gln Gly Tyr Asp
             260                 265                 270        
 Gly Phe Phe Val Ile Ser Val Glu Gln Tyr Pro Glu Leu Ser Asp Ser
         275                 280                 285            
 Ala Asn Asn Ile His Phe Met Arg Gln Ser Glu Met Gly Arg Arg
     290                 295                 300            



      <210> 2621
      <211> 755
      <212> PRT
      <213> Homo sapiens


      <400> 2621
 Leu Thr Arg Ala Pro Asp Pro Asp Arg Val Gly Leu Val Ala Asp Phe
   1               5                  10                  15    
 Leu Arg Leu Phe Ile Pro Thr Ala Lys Gly Pro Val Ile Asn Ala Pro
              20                  25                  30        
 Leu Pro Gln Arg Leu Arg Ser Asn Thr Ala Pro Ile Arg Thr Leu His
          35                  40                  45            
 Ala Pro Ser Val His Arg Pro Thr Gly Arg Glu Ser Met Pro Arg Thr
      50                  55                  60                
 Arg Leu Thr Arg Ala Arg Thr Ser Pro Asp Thr Thr Gly Ser Asp Lys
  65                  70                  75                  80
 Thr Pro His Pro Arg Pro Lys Thr Leu Pro Ile Gln Thr Arg Ser Cys
                  85                  90                  95    
 Ala Asp Ser Gly Lys Leu Ser Glu Ile Arg Lys Ile Asp Asp Pro Leu
             100                 105                 110        
 Gln His His Leu Gln Asn Gln Ser Ile Gln Lys Ser Val Lys Gln Cys
         115                 120                 125            
 His Glu Gln Asn Met Phe Gly Asn Ile Val Asn Gln Asn Lys Gly His
     130                 135                 140                
 Phe Leu Leu Lys Gln Asp Cys Asp Thr Phe Asp Leu His Glu Lys Pro
 145                 150                 155                 160
 Leu Lys Ser Asn Leu Ser Phe Glu Asn Gln Lys Arg Ser Ser Gly Leu
                 165                 170                 175    
 Lys Asn Ser Ala Glu Phe Asn Arg Asp Gly Lys Ser Leu Phe His Ala
             180                 185                 190        
 Asn His Lys Gln Phe Tyr Thr Glu Met Lys Phe Pro Ala Ile Ala Lys
         195                 200                 205            
 Pro Ile Asn Lys Ser Gln Phe Ile Lys Gln Gln Arg Thr His Asn Ile
     210                 215                 220                
 Glu Asn Ala His Val Cys Ser Glu Cys Gly Lys Ala Phe Leu Lys Leu
 225                 230                 235                 240
 Ser Gln Phe Ile Asp His Gln Arg Val His Thr Gly Glu Lys Pro His
                 245                 250                 255    
 Val Cys Ser Met Cys Gly Lys Ala Phe Ser Arg Lys Ser Arg Leu Met
             260                 265                 270        
 Asp His Gln Arg Thr His Thr Glu Leu Lys His Tyr Glu Cys Thr Glu
         275                 280                 285            
 Cys Asp Lys Thr Phe Leu Lys Lys Ser Gln Leu Asn Ile His Gln Lys
     290                 295                 300                
 Thr His Met Gly Gly Lys Pro Tyr Thr Cys Ser Gln Cys Gly Lys Ala
 305                 310                 315                 320
 Phe Ile Lys Lys Cys Arg Leu Ile Tyr His His Arg Thr His Thr Gly
                 325                 330                 335    
 Glu Lys Pro His Gly Cys Ser Val Cys Gly Lys Ala Phe Ser Thr Lys
             340                 345                 350        
 Phe Ser Leu Thr Thr His Gln Lys Thr His Thr Gly Glu Lys Pro Tyr
         355                 360                 365            
 Ile Cys Ser Glu Cys Gly Lys Gly Phe Ile Glu Lys Arg Arg Leu Thr
     370                 375                 380                
 Ala His His Arg Thr His Thr Gly Glu Lys Pro Phe Ile Cys Asn Lys
 385                 390                 395                 400
 Cys Gly Lys Gly Phe Thr Leu Lys Asn Ser Leu Ile Thr His Gln Gln
                 405                 410                 415    
 Thr His Thr Gly Glu Lys Leu Tyr Thr Cys Ser Glu Cys Gly Lys Gly
             420                 425                 430        
 Phe Ser Met Lys His Cys Leu Met Val His Gln Arg Thr His Thr Gly
         435                 440                 445            
 Glu Lys Pro Tyr Lys Cys Asn Glu Cys Gly Lys Gly Phe Ala Leu Lys
     450                 455                 460                
 Ser Pro Leu Ile Arg His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr
 465                 470                 475                 480
 Val Cys Thr Glu Cys Arg Lys Gly Phe Thr Met Lys Ser Asp Leu Ile
                 485                 490                 495    
 Val His Gln Arg Thr His Thr Ala Glu Lys Pro Tyr Ile Cys Asn Asp
             500                 505                 510        
 Cys Gly Lys Gly Phe Thr Val Lys Ser Arg Leu Ile Val His Gln Arg
         515                 520                 525            
 Thr His Thr Gly Glu Lys Pro Tyr Val Cys Gly Glu Cys Gly Lys Gly
     530                 535                 540                
 Phe Pro Ala Lys Ile Arg Leu Met Gly His Gln Arg Thr His Thr Gly
 545                 550                 555                 560
 Glu Lys Pro Tyr Ile Cys Asn Glu Cys Gly Lys Gly Phe Thr Glu Lys
                 565                 570                 575    
 Ser His Leu Asn Val His Arg Arg Thr His Thr Gly Glu Lys Pro Tyr
             580                 585                 590        
 Val Cys Ser Glu Cys Gly Lys Gly Leu Thr Gly Lys Ser Met Leu Ile
         595                 600                 605            
 Ala His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Ile Cys Asn Glu
     610                 615                 620                
 Cys Gly Lys Gly Phe Thr Met Lys Ser Thr Leu Ser Ile His Gln Gln
 625                 630                 635                 640
 Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Asn Glu Cys Asp Lys Thr
                 645                 650                 655    
 Phe Arg Lys Lys Thr Cys Leu Ile Gln His Gln Arg Phe His Thr Gly
             660                 665                 670        
 Lys Thr Ser Phe Ala Cys Thr Glu Cys Gly Lys Phe Ser Leu Arg Lys
         675                 680                 685            
 Asn Asp Leu Ile Thr His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr
     690                 695                 700                
 Lys Cys Ser Asp Cys Gly Lys Ala Phe Thr Thr Lys Ser Gly Leu Asn
 705                 710                 715                 720
 Val His Gln Arg Lys His Thr Gly Glu Arg Pro Tyr Gly Cys Ser Asp
                 725                 730                 735    
 Cys Gly Lys Ala Phe Ala His Leu Ser Ile Leu Val Lys His Lys Arg
             740                 745                 750        
 Ile His Arg
         755



      <210> 2622
      <211> 677
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(677)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2622
 Met Lys Leu Met Glu Thr Leu Asn Gln Cys Ile Asn Ala Gly His Glu
   1               5                  10                  15    
 Met Thr Lys Ala Ile Ala Ile Ala Gln Phe Asn Asp Asp Ser Pro Glu
              20                  25                  30        
 Ala Arg Lys Ile Thr Arg Arg Trp Arg Ile Gly Glu Ala Ala Asp Leu
          35                  40                  45            
 Val Gly Val Ser Ser Gln Ala Ile Arg Asp Ala Glu Lys Ala Gly Arg
      50                  55                  60                
 Leu Pro His Pro Asp Met Glu Ile Arg Gly Arg Val Glu Gln Arg Val
  65                  70                  75                  80
 Gly Tyr Thr Ile Glu Gln Ile Asn His Met Arg Asp Val Phe Gly Thr
                  85                  90                  95    
 Arg Leu Arg Arg Ala Glu Asp Val Phe Pro Pro Val Ile Gly Val Ala
             100                 105                 110        
 Ala His Lys Glu Asn Thr Leu Leu Pro Phe Tyr Leu Gly Glu Lys Gly
         115                 120                 125            
 Asp Val Thr Tyr Ala Ile Lys Pro Leu Ala Gly Arg Gly Leu Thr Tyr
     130                 135                 140                
 Phe Phe Leu Ser Gly Ser Ala Arg Ile Glu Asn Glu Leu Met Gly Lys
 145                 150                 155                 160
 Phe Val Glu Arg Lys Leu Ala Thr His Thr Thr Leu Ser Phe Asp Trp
                 165                 170                 175    
 Pro Leu Glu Thr Thr Pro Gln Leu Leu Pro Pro His Ile Leu Ser Pro
             180                 185                 190        
 Val Phe Ala Ser Ala Ser Pro Ser Arg Cys Trp Arg Val Ala Ser Gly
         195                 200                 205            
 Lys Tyr Cys Lys Val Phe Arg Gly Ser Gly Phe Gln Ala Gln Xaa Ile
     210                 215                 220                
 Pro Gln Pro Thr Leu Arg Asp Pro His Tyr Val Glu Asp Lys Gly His
 225                 230                 235                 240
 Lys Tyr Leu Val Phe Glu Ala Asn Thr Gly Thr Glu Asn Gly Tyr Gln
                 245                 250                 255    
 Gly Glu Glu Ser Leu Phe Asn Lys Ala Tyr Tyr Gly Gly Gly Thr Asn
             260                 265                 270        
 Phe Phe Arg Lys Glu Ser Gln Lys Leu Gln Gln Ser Ala Lys Lys Arg
         275                 280                 285            
 Asp Ala Glu Leu Ala Asn Gly Ala Leu Gly Ile Ile Glu Leu Asn Asn
     290                 295                 300                
 Asp Tyr Thr Leu Lys Lys Val Met Lys Pro Leu Ile Thr Ser Asn Thr
 305                 310                 315                 320
 Val Thr Asp Glu Ile Glu Arg Ala Asn Val Phe Lys Met Asn Gly Lys
                 325                 330                 335    
 Trp Tyr Leu Phe Thr Asp Ser Arg Gly Ser Lys Met Thr Ile Asp Gly
             340                 345                 350        
 Ile Asn Ser Asn Asp Ile Tyr Met Leu Gly Tyr Val Ser Asn Ser Leu
         355                 360                 365            
 Thr Gly Pro Tyr Lys Pro Leu Asn Lys Thr Gly Leu Val Leu Gln Met
     370                 375                 380                
 Gly Leu Asp Pro Asn Asp Val Thr Phe Thr Tyr Ser His Phe Ala Val
 385                 390                 395                 400
 Pro Gln Ala Lys Gly Asn Asn Val Asn Arg Phe Thr Gln Phe Arg Leu
                 405                 410                 415    
 Ser Glu Thr Lys Glu Ile Thr Asn Pro Tyr Ala Met Arg Leu Tyr Glu
             420                 425                 430        
 Ser Leu Cys Gln Tyr Arg Lys Pro Asp Gly Ser Gly Ile Val Ser Leu
         435                 440                 445            
 Lys Ile Asp Trp Ile Ile Glu Arg Tyr Gln Leu Pro Gln Ser Tyr Gln
     450                 455                 460                
 Arg Met Pro Asp Phe Arg Arg Arg Phe Leu Gln Gly Gln Phe Asp His
 465                 470                 475                 480
 Ala Ala Ser Pro Val Glu Arg Gly His Leu Arg Lys Ile Pro Phe Arg
                 485                 490                 495    
 Gly Gly Thr Arg Glu Ser Arg Glu Arg Gly Leu Ser Glu Ala Gly Tyr
             500                 505                 510        
 Leu Pro Arg Glu Ala Gly Gln Ala Gln Lys Arg Arg Pro Trp Thr Lys
         515                 520                 525            
 Gly Pro Leu Glu Lys Ile Gly Leu Glu Thr Leu His Cys Asp Ser Arg
     530                 535                 540                
 Arg Tyr Pro Cys Arg Ser Asn Trp Val Trp Ile Cys Thr Val Lys Glu
 545                 550                 555                 560
 Gly Gly Arg Glu Gly Arg Gly Gly Arg Gly Arg Arg Val Gln Leu Ala
                 565                 570                 575    
 Ala Val Ala Gly Thr Val Ala Pro Ala Ala Ala Pro Lys Asn Pro Pro
             580                 585                 590        
 Pro Arg Phe Arg Trp Ser Val Trp Ala Arg Asp Gly Val Lys Glu Arg
         595                 600                 605            
 Val Pro Leu Gln Ala Gly Val Gly Gly Gly Gln Ala Val Gln Arg Arg
     610                 615                 620                
 Glu Thr Ala Arg Arg Ser Arg Gly Trp Leu Leu Arg Ile Trp Asp Ser
 625                 630                 635                 640
 Ile Gly Arg Asp Arg Ser Leu Gly Gly Asn Gly Phe Phe Thr Thr Ala
                 645                 650                 655    
 Asp Gln Arg Phe Asp Phe Ala Val Leu Trp Leu Val Ala Phe Arg Ile
             660                 665                 670        
 Asn Ser Asp Lys Leu
         675        



      <210> 2623
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 2623
 Thr Gly Thr Ala Trp Thr Pro Pro Pro Pro Pro Leu Thr Thr Gly Ala
   1               5                  10                  15    
 Pro Cys Thr Pro Pro Pro Arg Cys Thr Ala Arg Gly Arg Thr Pro Gly
              20                  25                  30        
 Asp Ser His Leu Gly Gly Gly Pro Ala Ala Thr Ala Gly Gly Pro Arg
          35                  40                  45            
 Thr Ser Pro Met Ser Ser Gly Gly Pro Ser Ala Pro Gly Met Arg Pro
      50                  55                  60                
 Pro Ala Ser Ser Pro Lys Arg Asn Thr Thr Ser Leu Leu Asn Ser Gly
  65                  70                  75                  80
 Leu Glu Pro Thr Phe Ser Phe Arg Ile Thr Phe Gly Phe Met
                  85                  90                



      <210> 2624
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 2624
 Met Pro Leu Leu Glu Tyr Ala Arg Asn Met Leu Arg Thr Trp Ser Ser
   1               5                  10                  15    
 Leu Pro Trp Thr Arg Phe Arg Val Cys Leu Leu Ser Leu Ser Leu Phe
              20                  25                  30        
 Leu Trp Ala Asn Arg Leu Glu Asp Ser Arg Ser Cys Gln Pro Asn Pro
          35                  40                  45            
 Met Ser Leu Thr Thr Leu Pro Gly His Arg Leu Lys Glu Ala Val Trp
      50                  55                  60                
 Leu Pro Ala Pro Ser Arg Thr Met Ser Pro His Leu Asp Pro Asn Gln
  65                  70                  75                  80
 Leu Gly Ile Leu Leu Arg Val Leu Arg Lys Glu Lys Glu Asp Gly Asp
                  85                  90                  95    
 Tyr Pro Asp Met Met Ala Thr His Pro Ser Ser Arg Tyr Glu Ala Cys
             100                 105                 110        
 Ser Ser Gly Ile Thr Leu Ala Ala Pro Pro Thr His Gly Pro Arg Pro
         115                 120                 125            
 Thr Asp Pro Arg Ile Gly Pro Ala Pro
     130                 135        



      <210> 2625
      <211> 440
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(440)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2625
 Met Ala Ile Leu Pro Lys Val Ile Tyr Arg Phe Asn Ala Ile Pro Ile
   1               5                  10                  15    
 Lys Leu Pro Val Thr Phe Phe Thr Glu Leu Gly Lys Thr Thr Leu Arg
              20                  25                  30        
 Phe Ile Trp Asn Gln Lys Arg Ala Cys Ile Gly Lys Ser Val Leu Ser
          35                  40                  45            
 Gln Lys Asn Lys Ala Gly Gly Ile Thr Leu Pro Asp Phe Lys Leu Tyr
      50                  55                  60                
 Tyr Lys Ala Thr Val Thr Lys Thr Ala Trp Tyr Trp Tyr Gln Asn Arg
  65                  70                  75                  80
 Asp Ile Asp Gln Trp Asn Arg Thr Glu Ser Ser Glu Ile Met Leu His
                  85                  90                  95    
 Ile Tyr Asn His Leu Ile Phe Asp Lys Pro Asp Lys Asn Lys Lys Trp
             100                 105                 110        
 Gly Lys Asp Ser Leu Phe Asn Lys Trp Cys Trp Glu Asn Trp Leu Ala
         115                 120                 125            
 Ile Cys Arg Lys Leu Lys Leu Asp Pro Phe Leu Thr Ser His Thr Lys
     130                 135                 140                
 Ile Asn Ser Arg Trp Ile Lys Asp Leu Asn Val Arg Pro Lys Thr Ile
 145                 150                 155                 160
 Lys Thr Leu Glu Glu Asn Leu Gly Asn Thr Ile Gln Ala Ile Gly Met
                 165                 170                 175    
 Gly Lys Asp Phe Met Thr Lys Thr Pro Lys Ala Met Ala Thr Lys Ala
             180                 185                 190        
 Lys Ile Asp Lys Trp Asp Leu Ile Lys Leu Lys Ser Phe Cys Thr Ala
         195                 200                 205            
 Lys Glu Thr Thr Ile Arg Leu Leu Gly Arg Pro Pro Ala Leu Phe Thr
     210                 215                 220                
 Ala Ser Ser Ser Val Leu Lys Gln Leu Ala Leu Glu Gly Ile Leu Ile
 225                 230                 235                 240
 Leu Asp Ser Arg Ala Leu Leu Gly Phe Leu Tyr Glu Ala Arg His Ser
                 245                 250                 255    
 His Ser Asn Ser Pro Asn His Asp Ala Gln Asn Ala Thr Ser Lys Lys
             260                 265                 270        
 Asn Ile Arg Asp Gly Tyr Asp Lys Ile Tyr Arg Gln Glu Gln Val Leu
         275                 280                 285            
 Ala Arg Met Glu Glu Lys Thr Leu Ile Thr Ala Gly Gly Asn Val Lys
     290                 295                 300                
 Trp Cys Ser His Phe Arg Lys Gln Ile Gly Gly Gln Trp Leu Thr Leu
 305                 310                 315                 320
 Glu Thr Lys Thr Lys Thr Pro Gln Pro Phe Ser Ser Thr Ser Gln Ile
                 325                 330                 335    
 Ser Thr Asp Lys Asp Lys Gly Leu Asn Pro Gln Leu Leu Lys Met Asp
             340                 345                 350        
 Pro Gly His Met Gly Trp Cys Pro Pro Gly Met Gly Ile Pro Trp Gln
         355                 360                 365            
 Leu Ser Ser Asp Asp Arg Val Trp Val Leu Ala Ala Ala Gly Ser Gly
     370                 375                 380                
 Arg His Pro Gly Ser Gly Phe Lys Ser Leu Pro Gly Leu Leu His Glu
 385                 390                 395                 400
 Gly Ser Tyr Gly His Xaa Xaa Xaa Xaa Ser Xaa Ile Xaa Gly Gly Asn
                 405                 410                 415    
 Ser Xaa Gly Ser Ser Gly Gly Pro Gln Cys Ile Ser Gly Glu Glu Arg
             420                 425                 430        
 Val Phe Arg Val Val Gln Ser Ile
         435                 440



      <210> 2626
      <211> 67
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(67)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2626
 Val Ser Asn Ile Val Asp Pro His Gln Thr Val Gly Leu Ser Thr Gln
   1               5                  10                  15    
 Glu Pro Gly Asp Ile Phe Thr Tyr Ser Glu Phe Asp Gly Ile Leu Gly
              20                  25                  30        
 Leu Ala Tyr Pro Ser Leu Ala Ser Glu Xaa Ser Val Pro Val Leu Asp
          35                  40                  45            
 Asn Thr Met Gln Arg His Leu Val Ala Gln Asp Leu Phe Ser Val Tyr
      50                  55                  60                
 Met Ser Arg
  65        



      <210> 2627
      <211> 138
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(138)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2627
 Glu Phe Phe His His Val Gly Gln Asp Gly Leu Asp Leu Leu Thr Ser
   1               5                  10                  15    
 Xaa Ser Ala His Leu Gly Leu Leu Lys Cys Trp Asp Tyr Arg Arg Glu
              20                  25                  30        
 Pro Pro Arg Pro Ala Ser Asp Gly His Tyr Xaa Thr Asp Ala Thr Gly
          35                  40                  45            
 Ser Leu Pro Ser Ser Gly Thr Thr Xaa Ile Arg Thr Lys Pro Ser Gln
      50                  55                  60                
 Ala Pro Ala Ser Trp Gly Leu Trp Asn Leu Ala His His Pro Pro Arg
  65                  70                  75                  80
 Ser His Pro Ser Cys Pro Met Ala Asn Leu Ile Cys Ser Thr Leu Ser
                  85                  90                  95    
 Ser Phe Asp Gly Gly Ser Pro Gly Thr Gly Pro Gly Gly Trp Cys Pro
             100                 105                 110        
 Leu Gly Leu Ser Gly Ser Pro Ala Arg Ala Val Phe Lys Asp Ser Ser
         115                 120                 125            
 Cys Ser Leu His Pro Leu Ala Thr Gly Ile
     130                 135            



      <210> 2628
      <211> 95
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(95)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2628
 Arg Gln Gly Phe Pro Leu Cys Asn His Lys Gly Thr Val Thr Ala Asp
   1               5                  10                  15    
 Leu Gln Pro Leu Pro Pro Gly Leu Lys Xaa Ile Ser His Leu Ser Leu
              20                  25                  30        
 Leu Ser Ser Trp Asn Tyr Arg Cys Thr Pro Pro His Pro Ala Asp Phe
          35                  40                  45            
 Xaa Phe Phe Val Glu Arg Arg Ser His Tyr Val Ala Xaa Ala Cys Leu
      50                  55                  60                
 Glu Leu Leu Cys Ser Ser Asp Leu Pro Ala Leu Ile Ser Gln Arg Val
  65                  70                  75                  80
 Gly Ile Thr Gly Met Ser Thr Thr Pro Gly Pro Ile Cys Leu Leu
                  85                  90                  95



      <210> 2629
      <211> 267
      <212> PRT
      <213> Homo sapiens


      <400> 2629
 Met Val Ile Val Gly Leu Ala Ala Gly Val Leu Leu Val Gly Pro Gly
   1               5                  10                  15    
 Asp Gly Gly Leu Ile Ser Glu Gly Val Val Arg Glu Asp Leu Met Cys
              20                  25                  30        
 Gly Val Trp Ser Ala Gly Thr Trp Ser Val Gly Thr Ala Glu Arg Cys
          35                  40                  45            
 Leu Glu Lys Pro Gly Ala Leu His Val Ile Glu Gly Pro Leu Asp Ser
      50                  55                  60                
 Trp Asp Gly Pro Val Met Pro Asn Gly Pro Val Lys Asn His Lys Gly
  65                  70                  75                  80
 Glu Gln Gln Glu Val Pro Ser Lys His Pro Gln Met Ala Leu Glu Ile
                  85                  90                  95    
 Cys Leu Cys Leu Asp Phe Leu Tyr Tyr Pro Phe Leu Arg Gly Asp Ala
             100                 105                 110        
 Ser Ala Gly Pro Val Thr Trp Cys Thr Thr Ser Asp Thr Ile Ile Leu
         115                 120                 125            
 Gln Gln His Arg Thr Leu Thr Ser Gln Gly Val Asp Asp Phe Leu Lys
     130                 135                 140                
 Ala Lys Ala Thr Phe Lys Ala Ser Asp Phe Ile Asp Ala Leu Val Leu
 145                 150                 155                 160
 Ser Lys Asp Leu Asn Ser Gly Gly Arg Met Glu Leu Glu Ile Lys Cys
                 165                 170                 175    
 Leu Ile Lys Val Leu Glu Leu Asp Leu Glu Gly Ser Gly Glu Pro Trp
             180                 185                 190        
 Lys Val Leu Asp Lys Gly Val Thr Val Ser Tyr Val Phe Glu Met Thr
         195                 200                 205            
 Ile Glu Gly Cys Leu Glu Gly Val Asn Lys Ser Gln Glu Thr Arg Glu
     210                 215                 220                
 Gly Ala Cys Gly Ala Gly Leu Glu Met Ala Lys Glu Gly Ser Cys Leu
 225                 230                 235                 240
 Asp Glu Arg Ser Ser Gly Thr Val Ser Gly Tyr Thr Gln Val Ser Ser
                 245                 250                 255    
 Glu Leu Val Cys Ser Gly Phe Leu Ser Pro Gly
             260                 265        



      <210> 2630
      <211> 76
      <212> PRT
      <213> Homo sapiens


      <400> 2630
 Gly Gly Gly Ser Ser Pro Arg Glu Leu Ala Gly Ala Ala Gly Leu Thr
   1               5                  10                  15    
 Val Thr Ser Gln Ala Val Ala Ala Arg Arg Gln Gln Pro Ser Phe Ser
              20                  25                  30        
 Arg Ala Arg Ala Pro Ala His Ser Leu Arg Ala Ala Leu Ser Leu Ala
          35                  40                  45            
 Ser Ser Ala Arg Ser Trp Gly Ala Val Ser Arg Asp Arg Gly Pro Cys
      50                  55                  60                
 Pro Pro Ala Ile Met Tyr Gln Ser Ser Asn Lys Cys
  65                  70                  75    



      <210> 2631
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2631
 Met Leu Val Pro Val Leu Ile Leu Ser Pro Cys Leu Val Gly Ile Glu
   1               5                  10                  15    
 Pro Trp Glu Val Ser Pro His Thr Asn Ser Thr Ser Ser Tyr Glu Ser
              20                  25                  30        
 Thr Pro Lys Ser Tyr Pro Leu Gly Thr Ala Ala Lys Ala Ala Ser Gly
          35                  40                  45            
 Gln Ser Pro Ser Thr Thr Ser Pro Leu Pro Glu Thr Ala Pro Ser Thr
      50                  55                  60                
 Leu His Glu Arg Gly Leu Glu Asn Val Val Cys Ser Asp Lys Asp Leu
  65                  70                  75                  80
 Arg Gln Ala Thr Gly Tyr Ser Ala Ala Glu Lys Ser Lys Pro Pro Gly
                  85                  90                  95    
 Leu Cys Thr Arg Ala Phe Cys Pro Glu Ala Ile Pro Asp Ala Gln Asp
             100                 105                 110        
 Trp Val Lys Cys Gln Pro Leu Gly Ser Leu Ser Ala Leu Asn Phe
         115                 120                 125        



      <210> 2632
      <211> 91
      <212> PRT
      <213> Homo sapiens


      <400> 2632
 Lys Thr Ser Gln Asp Thr Lys Pro Ser Val Leu Trp Lys Asp Val Asn
   1               5                  10                  15    
 Ser Asn Leu Trp Cys Arg Pro His Asp Leu Leu Thr Trp Gly Arg Gly
              20                  25                  30        
 Tyr Ala Cys Val His Ile Pro Ser Gly Pro Leu Gly Ile Pro Val Gln
          35                  40                  45            
 Cys Ile Lys Pro Tyr His Gly Met Ala Gly Thr Gln Cys Ser Thr Gly
      50                  55                  60                
 Asn Glu Glu Cys Glu Pro Val Gly Pro Ala Ala Pro Asp Asn Ala Ala
  65                  70                  75                  80
 Ser Ser Asp Asn Thr Gly Pro Gly Trp Gly Met
                  85                  90    



      <210> 2633
      <211> 1141
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1141)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2633
 Xaa Gly Lys Pro Glu Lys Phe Ser Phe Gly Leu Leu Asp Leu Pro Phe
   1               5                  10                  15    
 Arg Val Gly Val Pro Phe Asn Ile Pro Leu Glu Phe Gln Asp Glu Phe
              20                  25                  30        
 Gly His Thr Ser Gln Leu Val Thr Asp Ile Gln Pro Val Leu Glu Ala
          35                  40                  45            
 Ser Gly Leu Ser Leu His Tyr Glu Glu Ile Thr Asn Gly Pro Asn Cys
      50                  55                  60                
 Val Ile Arg Gly Val Thr Ala Lys Gly Pro Val Asn Ser Cys Gln Gly
  65                  70                  75                  80
 Lys Val Ala Pro Asn Leu Pro Val Tyr Val Val Asp Cys Ser Ser Ser
                  85                  90                  95    
 Gly Thr Ser Ile Leu Thr Gly Ser Ala Ile Gln Val Gln Asn Ile Lys
             100                 105                 110        
 Lys Asp Gln Thr Leu Lys Ala Arg Ile Glu Ile Pro Ser Cys Lys Asp
         115                 120                 125            
 Val Ala Pro Val Glu Lys Thr Ile Lys Leu Leu Pro Ser Ser His Val
     130                 135                 140                
 Ala Arg Leu Gln Ile Phe Ser Val Glu Gly Gln Lys Ala Ile Gln Ile
 145                 150                 155                 160
 Lys His Gln Asp Glu Val Asn Trp Ile Ala Gly Asp Ile Met His Asn
                 165                 170                 175    
 Leu Ile Phe Gln Met Tyr Asp Glu Gly Glu Arg Glu Ile Asn Ile Thr
             180                 185                 190        
 Ser Ala Leu Ala Glu Lys Ile Lys Gly Leu Leu Pro Asp Val Gln Val
         195                 200                 205            
 Pro Thr Ser Val Lys Asp Met Arg Tyr Cys Gln Val Ser Phe Gln Asp
     210                 215                 220                
 Asp His Val Ser Leu Glu Ser Ala Phe Thr Val Ser Met Leu Glu Leu
 225                 230                 235                 240
 Leu Gln Leu Met Val Ser Leu Lys Thr Ser Asn Leu Leu Asn Asn Phe
                 245                 250                 255    
 Arg Pro Leu Pro Asp Glu Pro Lys His Leu Lys Cys Glu Met Lys Gly
             260                 265                 270        
 Gly Lys Thr Val Gln Met Gly Gln Glu Leu Gln Gly Glu Val Val Ile
         275                 280                 285            
 Ile Ile Thr Asp Gln Tyr Gly Asn Gln Ile Gln Ala Phe Ser Pro Ser
     290                 295                 300                
 Ser Leu Ser Ser Leu Ser Ile Ala Gly Val Gly Leu Asp Ser Ser Asn
 305                 310                 315                 320
 Leu Lys Thr Thr Phe Gln Ser Ile Pro Val Ile Asn Gly Arg Asp Leu
                 325                 330                 335    
 Gln Asn Pro Ile Ile Val Gln Leu Cys Asp Gln Trp Asp Asn Pro Ala
             340                 345                 350        
 Pro Val Gln His Val Lys Ile Ser Leu Thr Lys Ala Ser Asn Leu Lys
         355                 360                 365            
 Val Lys Ala Ile Tyr Asn Lys Ser Ile Ile Glu Gly Pro Ile Ile Lys
     370                 375                 380                
 Leu Met Ile Leu Pro Asp Pro Glu Lys Pro Val Arg Leu Asn Val Lys
 385                 390                 395                 400
 Tyr Asp Lys Asp Ala Ser Phe Leu Ala Gly Gly Leu Phe Thr Gly Tyr
                 405                 410                 415    
 Val Arg Pro Val Pro Val Pro Arg Ser Leu Asn Ser Asp Ile Ser Tyr
             420                 425                 430        
 Phe Gly Val Gly Gly Lys Gln Ala Val Phe Phe Val Gly Gln Ser Ala
         435                 440                 445            
 Arg Met Ile Ser Lys Pro Ala Asp Ser Gln Asp Val His Glu Leu Val
     450                 455                 460                
 Leu Ser Lys Glu Asp Phe Glu Lys Lys Glu Lys Asn Lys Glu Ala Ile
 465                 470                 475                 480
 Tyr Ser Gly Tyr Ile Arg Asn Arg Lys Ile Ser Met Phe Glu Lys Gly
                 485                 490                 495    
 Lys Val Pro Lys Ile Val Asn Leu Arg Glu Ile Gln Asp Asp Met Gln
             500                 505                 510        
 Thr Leu Tyr Val Asn Thr Ala Ala Asp Ser Phe Glu Phe Lys Ala His
         515                 520                 525            
 Val Glu Gly Asp Gly Val Val Glu Gly Ile Ile Pro Tyr His Pro Phe
     530                 535                 540                
 Leu Tyr Asp Arg Glu Thr Tyr Pro Asp Asp Pro Cys Phe Pro Ser Asn
 545                 550                 555                 560
 Asn Phe Gly Ile Ser Phe Val His Ser Leu Glu Val Ile Leu Xaa Leu
                 565                 570                 575    
 Lys Asp Glu Asp Asp Glu Asp Asp Cys Phe Ile Leu Glu Lys Ala Ala
             580                 585                 590        
 Arg Gly Lys Arg Pro Ile Phe Glu Cys Phe Trp Asn Gly Arg Leu Ile
         595                 600                 605            
 Pro Tyr Thr Ser Val Glu Asp Arg Gly Leu Ala Pro Ile Glu Cys Tyr
     610                 615                 620                
 Asn Arg Ile Ser Gly Ala Leu Phe Thr Asn Asp Lys Phe Gln Val Ser
 625                 630                 635                 640
 Thr Asn Lys Leu Thr Phe Met Asp Leu Glu Leu Lys Leu Lys Asp Lys
                 645                 650                 655    
 Asn Thr Leu Phe Thr Arg Ile Leu Asn Gly Gln Glu Gln Arg Met Lys
             660                 665                 670        
 Ile Asp Arg Glu Phe Ala Leu Trp Leu Lys Asp Cys His Glu Lys Tyr
         675                 680                 685            
 Asp Lys Gln Ile Lys Phe Thr Leu Phe Lys Gly Val Ile Thr Arg Pro
     690                 695                 700                
 Asp Leu Pro Ser Lys Lys Gln Gly Pro Trp Ala Thr Tyr Ala Ala Ile
 705                 710                 715                 720
 Glu Trp Asp Gly Lys Ile Tyr Lys Ala Gly Gln Leu Glu Pro Gln Ala
                 725                 730                 735    
 Leu Tyr Asp Glu Val Arg Thr Val Pro Ile Ala Lys Leu Asp Arg Thr
             740                 745                 750        
 Val Ala Glu Lys Ala Val Lys Lys Tyr Val Glu Asp Glu Met Ala Ser
         755                 760                 765            
 Leu Trp Ile Leu Gly Tyr Lys Pro Val Gln His Met Thr Val Leu Ser
     770                 775                 780                
 Thr Ala Gly Asn Cys Asn Thr Thr Phe Trp Lys Lys Ile Asn Ile Thr
 785                 790                 795                 800
 Val Ile Leu Arg Cys Arg Ser Leu Thr Lys Val Leu Leu Ala Thr Glu
                 805                 810                 815    
 Arg Thr Phe Glu Thr Ala Gly Val Gly Gly Leu Ile Leu Gly Gln Val
             820                 825                 830        
 Glu Glu Ala Arg Leu Lys Glu Ala Gln Leu Arg Asn Glu Leu Lys Ile
         835                 840                 845            
 His Asn Ile Asp Ile Pro Thr Thr Gln Gln Val Pro His Ile Glu Ala
     850                 855                 860                
 Leu Leu Lys Arg Lys Leu Ser Glu Gln Glu Glu Leu Lys Lys Lys Pro
 865                 870                 875                 880
 Arg Arg Ser Cys Thr Leu Pro Asn Tyr Thr Lys Gly Ser Gly Asp Val
                 885                 890                 895    
 Leu Gly Lys Gly Gln Ser Thr Gly Leu Gly Pro Val Glu Val Thr Gln
             900                 905                 910        
 Ser Ser Pro Ser Ser Arg Thr Ser Glu Tyr Phe Trp Leu Thr Lys Phe
         915                 920                 925            
 Cys Trp Leu Glu Asp Trp Ala Ser Gly Glu Ser Leu Arg Leu Leu Pro
     930                 935                 940                
 Leu Met Val Glu Gly Glu Gly Glu Pro Val Tyr Ala Glu Ile Ile Trp
 945                 950                 955                 960
 Gln Lys Arg Asp Glu Thr Val Lys Asp Gly Val Thr Leu Tyr Leu Leu
                 965                 970                 975    
 Gln Ser Val Asn Gln Leu Leu Leu Thr Ala Thr Lys Glu Arg Ile Asp
             980                 985                 990        
 Phe Leu Pro His Tyr Asp Thr Leu Val Lys Ser Gly Met Tyr Glu Tyr
         995                1000                1005            
 Tyr Ala Ser Glu Gly Gln Asn Pro Leu Xaa Ile Tyr Thr His Val Gly
    1010                1015                1020                
 Asp Arg Glu Ala Gln Ala Ala Leu Lys Leu Gly Arg Trp Ser His Pro
1025                1030                1035                1040
 Arg Thr Pro Asn Ala Val Gly Ala Pro Gly Pro Pro Glu Gly Ala Gly
                1045                1050                1055    
 Gly Gly Asp Ala Val Thr Ser Gln Ser Ala Leu Leu Thr Phe Ser Arg
            1060                1065                1070        
 Thr Arg Phe Ala Ser Gly Ala His Ala Gly Ala His Pro Val Leu Leu
        1075                1080                1085            
 Arg Asn Glu Glu Glu Lys Gly Ala Pro Ala Leu Val Ala Pro Ile Phe
    1090                1095                1100                
 Ser Ala Glu Gly Pro Thr Cys Ser Leu Trp Trp Thr Leu Arg Pro Ala
1105                1110                1115                1120
 Ser Thr Ala Gly Leu Lys Leu Pro Ala Arg Arg Val His Ala Thr Gln
                1125                1130                1135    
 Pro Glu Arg Ala His
            1140    



      <210> 2634
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2634
 Met Leu Ala Ser Pro Leu Trp Leu Gln Ala Leu Ser Leu Ala Ala Gly
   1               5                  10                  15    
 Thr Trp Arg Pro Arg Leu Gly Ser Gly Gln Ala Gly Asn Ser Glu Met
              20                  25                  30        
 Arg Ala Gly Phe Leu Pro Gly Ala Gly Ser Gln Val Arg Ala Gln Leu
          35                  40                  45            
 Gln Asp Arg Leu Pro Lys Thr Thr Glu Thr Lys Gly Ala Leu Trp Pro
      50                  55                  60                
 His Thr Glu Leu Cys Gly Met Trp Ser Ile Ala Pro Gly Ala Glu Asn
  65                  70                  75                  80
 Gln Glu Leu Gln Ile Asp Ser Pro Leu Leu Gly Gln Leu Ser Asn Gln
                  85                  90                  95    
 Val Trp Arg Glu Asp Gly Tyr Gly Lys Ala Phe Arg Leu Arg Thr Leu
             100                 105                 110        
 Ser Ser Met Gly Ile Thr Glu Glu Ala Asn Glu Asn Val Leu Ile
         115                 120                 125        



      <210> 2635
      <211> 162
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(162)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2635
 Phe Phe Ile Ser Val Ile Asn Gly Gln Val Ser Ser Val Gln Arg Leu
   1               5                  10                  15    
 Ser Gly Val Gly Pro Ala Cys Leu Ser Cys Gly Ser Ala Asn Pro Gly
              20                  25                  30        
 Pro Pro Pro Gly Thr Ser Pro Gly Ala Gly Ala Gln Arg Arg Xaa Pro
          35                  40                  45            
 Arg Ala Asp Gly Ser Gly Ser Pro Gln Trp Pro Arg Gly Ala Arg Val
      50                  55                  60                
 Gly Gly Gly Arg Leu Gly Thr Gly Gly Arg Gly Arg Pro Gly Trp Arg
  65                  70                  75                  80
 Gln Val Pro Arg Arg Leu Ser Pro Gly Phe Gly Arg Xaa Gly Gly Thr
                  85                  90                  95    
 Gly Pro Gly Pro Val Gly Thr Ser Gly Lys Arg Gly Pro Ser Arg Arg
             100                 105                 110        
 Arg Ala Pro Ala Asn Asp Lys Ala Ala Cys Trp Pro Arg Phe Pro Gly
         115                 120                 125            
 Gln Pro Ala Ser Xaa Thr Gly Phe Arg Gly Glu Arg Gly Val Lys Gly
     130                 135                 140                
 Phe Ser Ser Trp Gly Ser Gly Trp Arg Ala Trp Glu Asp Gly Gly Thr
 145                 150                 155                 160
 Val His
        



      <210> 2636
      <211> 242
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(242)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2636
 His Gly Leu Val Leu Asp Val Arg Gly Pro Leu Ser His Ala Ala Pro
   1               5                  10                  15    
 Tyr Trp Ala Pro Tyr Pro Ala Ala Thr Ala Ala Ala Ala Arg Thr Ala
              20                  25                  30        
 Pro Leu Pro Pro Arg Ser Ala Ile Val Xaa Ser Gly Pro Gln Pro Asp
          35                  40                  45            
 Phe Gln Glu Leu Arg Lys Thr Trp Pro Ser Gln Cys Gly Met Ala Arg
      50                  55                  60                
 Arg Glu Pro Leu Leu Pro Ile Thr Ala Ile Pro Arg Val Val Val Glu
  65                  70                  75                  80
 Thr Thr Pro Xaa Gly Phe Ala Lys Gln Glu Pro Ser Val Ala Gly Leu
                  85                  90                  95    
 Arg Cys Arg Gly Ser Glu Ala Pro Ala Xaa Leu Leu His Gly Val His
             100                 105                 110        
 Arg Asn Val Ser Glu Thr Pro Gly Pro Glu Met Gly Arg Pro Gly Xaa
         115                 120                 125            
 Gly Asn His Arg Gln Arg Pro Gly Lys Gln Arg Gly Ile Pro Ser Ser
     130                 135                 140                
 Gly Leu Pro Gly Arg Cys Ser Gly Ser Arg Gly Pro His Ser Ser Pro
 145                 150                 155                 160
 Gly Gln Lys Pro His Gly Ser Thr Leu Ser Gly Arg Arg Gly Ala Asp
                 165                 170                 175    
 Pro Arg Pro Arg Arg Arg Val Tyr Leu Ser Thr Pro Leu Leu Cys Glu
             180                 185                 190        
 Lys Lys Pro His His Asp Thr Ile Leu Lys Arg Lys Pro Gly Met Gly
         195                 200                 205            
 Asp Gly Asn Asn Pro Cys Pro Trp Asn Ala Gly Leu Tyr Gly Gln Ala
     210                 215                 220                
 Thr Arg Phe Ala Pro Leu Pro Leu Cys Pro Arg Arg Arg His Gly Ala
 225                 230                 235                 240
 Val Ser
        



      <210> 2637
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 2637
 Ser Pro Leu Arg Pro Leu Leu Leu Ala Leu Ala Leu Ala Ser Val Pro
   1               5                  10                  15    
 Cys Ala Gln Gly Ala Cys Pro Ala Ser Ala Asp Leu Lys His Ser Asp
              20                  25                  30        
 Gly Thr Arg Thr Cys Ala Lys Leu Tyr Asp Lys Ser Asp Pro Tyr Tyr
          35                  40                  45            
 Glu Asn Cys Cys Gly Gly Ala Glu Leu Ser Leu Glu Ser Gly Ala Asp
      50                  55                  60                
 Leu Pro Tyr Leu Pro Ser Asn Trp Ala Asn Thr Ala Ser Ser Leu Val
  65                  70                  75                  80
 Val Ala Pro Arg Cys Glu Leu Thr Val Trp Ser Arg Gln Gly Lys Ala
                  85                  90                  95    
 Gly Lys Thr His Lys Phe Ser Ala Gly Thr Tyr Pro Arg Leu Glu Glu
             100                 105                 110        
 Tyr Arg Arg Gly Ile Leu Gly Asp Trp Ser Asn Ala Ile Ser Ala Leu
         115                 120                 125            
 Tyr Cys Arg Cys Ser
     130            



      <210> 2638
      <211> 325
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(325)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2638
 Ile Asn Tyr Ser Leu Glu Lys His Val Gly Ala Leu Gly Arg Val Leu
   1               5                  10                  15    
 Phe Ser Leu Xaa Arg Ala Gly Cys Pro Gly Met Gly Ser Thr Arg Glu
              20                  25                  30        
 Arg Gly Leu Tyr Leu Gly Lys His Arg Gly Ser Gly Gly Ile Trp Xaa
          35                  40                  45            
 Ala Leu Ala Gly Pro Xaa Lys Ser Arg Gly Asp Ser Val Ser Leu Thr
      50                  55                  60                
 Gln Gly His Thr His Val Cys Ser Arg Ser Pro Arg Xaa Ala Asp Ser
  65                  70                  75                  80
 Pro Pro Gly Ser His Leu Ser Pro Val Pro His Ser Val Glu Val Ala
                  85                  90                  95    
 Gly His Val Leu Val Pro Ala Thr Arg Ala Ala Val Pro Cys Ser Ala
             100                 105                 110        
 Ser Ala Gly Ala Xaa Gln Ser Thr Tyr Arg Thr Gly Val His Gln Gly
         115                 120                 125            
 Asn Pro Thr Val Xaa Thr Lys Pro Ser Arg Arg Pro Ser Gly Gly Val
     130                 135                 140                
 Ala Lys Xaa Phe Leu Pro Ser Ala Val Arg Gly Glu Pro Gly Ala Lys
 145                 150                 155                 160
 Pro Leu Val Asp Asp Leu Leu Pro Gly Trp Ser Leu Ala Thr His Gly
                 165                 170                 175    
 Gln Pro Pro Leu Val Ala Ala Pro Gly Ser Gly Leu Trp Gly Arg Pro
             180                 185                 190        
 Ala Asp Ala Xaa Gly Cys Glu Thr Ala Gly Gly Ser Pro Cys Pro Arg
         195                 200                 205            
 Ser Thr Ser Arg Pro Ser Gly Pro Ser Gly Val Gln Gly Cys Pro Leu
     210                 215                 220                
 Gly Xaa Ala Gly Ser Gly Ala Ser Ala Ser Arg Ser Glu Pro Pro Gly
 225                 230                 235                 240
 Ser Thr Ser Cys Cys Pro Arg Ala Pro Thr Xaa Pro Ala Ala Pro Cys
                 245                 250                 255    
 Val Pro Asp Trp Pro Ala Gly Asp Gln Trp Arg Ser His Gly Tyr Leu
             260                 265                 270        
 Pro Pro Ser Arg Glu Leu Xaa Gly Trp Met Pro Pro Ser Arg Pro Ala
         275                 280                 285            
 Thr Leu Pro Gln Leu Ala Phe Ala Arg Gln Arg Gln Gly Asn Arg Phe
     290                 295                 300                
 Asp Ala Ala Phe Glu Ser Ser Gly Glu Asp Phe His Gln Met Pro Arg
 305                 310                 315                 320
 Val Gly Arg Met Gly
                 325



      <210> 2639
      <211> 487
      <212> PRT
      <213> Homo sapiens


      <400> 2639
 Met Arg Glu Leu Tyr Ser Ile Trp Leu Lys Gly Tyr Trp Thr Glu Gly
   1               5                  10                  15    
 Asp Trp Ala Gln Ser Pro Pro Arg Ser Pro Arg Glu Ala Leu Glu Gly
              20                  25                  30        
 Ile Arg Val His Leu Arg Cys Phe Lys Ala Tyr Gly Ile Ile Val Leu
          35                  40                  45            
 Cys Gln Cys Pro Trp Asn Thr Pro Leu Leu Pro Val Pro Lys Pro Gly
      50                  55                  60                
 Thr Lys His Tyr Glu Pro Val Gln Asp Leu Arg Leu Val Asn Gln Ala
  65                  70                  75                  80
 Thr Val Thr Leu His Pro Thr Val Pro Asn Pro Tyr Thr Leu Leu Gly
                  85                  90                  95    
 Leu Leu Pro Ala Glu Asp Ile Trp Phe Thr His Leu Asp Leu Lys Asp
             100                 105                 110        
 Ala Ile Cys Ser Ile Arg Ile Ala Pro Glu Ser Gln Lys Leu Phe Ala
         115                 120                 125            
 Phe Gln Trp Glu Asp Leu Gln Ser Gly Val Thr Thr Gln Tyr Thr Trp
     130                 135                 140                
 Asn Trp Leu Pro Gln Gly Trp Val Leu Lys Arg Val Asp Ala Leu Phe
 145                 150                 155                 160
 Gln His Leu Glu Asp Cys Gly Tyr Lys Val Pro Lys Lys Lys Ser Gln
                 165                 170                 175    
 Ile Cys Arg Gln Gln Val Arg Tyr Leu Gly Phe Thr Ile Trp Lys Gly
             180                 185                 190        
 Glu His Ser Leu Trp Ser Glu Arg Lys Gln Val Ile Cys Ser Leu Pro
         195                 200                 205            
 Glu Pro Lys Thr Arg Arg Gln Val Arg Glu Phe Leu Gly Ala Val Gly
     210                 215                 220                
 Phe Cys Thr Leu Trp Ile Pro Asn Phe Ala Val Leu Ala Lys His Leu
 225                 230                 235                 240
 Tyr Gly Ile Thr Lys Gly Gly Asn Trp Glu Pro Phe Glu Trp Gly Pro
                 245                 250                 255    
 Leu Gln Gln Gln Ala Phe Leu Ser Glu Ser Pro Val Glu His Asn Cys
             260                 265                 270        
 Val Glu Val Leu Asp Ser Val Tyr Ser Ser Arg Pro Asp Leu Arg Asp
         275                 280                 285            
 Gln Pro Trp Ala Ser Val Asp Leu Glu Leu Tyr Leu Asp Gly Ser Ser
     290                 295                 300                
 Phe Ile Asn Pro Gln Gly Glu Arg Cys Ala Glu Tyr Ala Val Val Thr
 305                 310                 315                 320
 Leu Asp Ala Val Ile Glu Thr Lys Pro Leu Pro Gln Gly Thr Ser Ala
                 325                 330                 335    
 Gln Lys Ala Glu Leu Ile Ala Leu Thr Arg Ala Leu Glu Leu Ser Glu
             340                 345                 350        
 Gly Asp Cys Ile Trp Ile Lys Asp Cys Asn Ile Ala Pro Leu Arg Pro
         355                 360                 365            
 Arg Trp Lys Gly Pro Gln Thr Val Ile Leu Thr Thr Pro Thr Ala Val
     370                 375                 380                
 Lys Arg Ser Ile Ala Ile Gly Asn Trp Gln Asp Asp Glu Trp Leu Pro
 385                 390                 395                 400
 Glu Arg Ile Thr Gln Tyr Tyr Gly Pro Ala Thr Trp Ala Gln Tyr Gly
                 405                 410                 415    
 Ser Trp Gly Tyr Tyr Asn Pro Ile Tyr Met Leu Asn Gln Met Ile Trp
             420                 425                 430        
 Leu Gln Ala Val Leu Glu Ile Thr Thr Asn Lys Thr Gly Arg Ala Leu
         435                 440                 445            
 Thr Ile Leu Ala Trp Gln Glu Thr Gln Met Arg Asn Pro Thr Tyr Gln
     450                 455                 460                
 Asp Arg Leu Ala Leu Asp Tyr Leu Leu Ala Ala Glu Gly Gly Val Cys
 465                 470                 475                 480
 Gly Lys Phe Asn Leu Thr Asn
                 485        



      <210> 2640
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 2640
 Met Ala Ile Ser Trp Lys Pro Thr Gly Leu Pro Trp His Ser Met Leu
   1               5                  10                  15    
 Gln Val Leu Leu Ala Ala Trp Leu Pro Gly Pro Thr Pro Thr Pro His
              20                  25                  30        
 Ser Ala Leu Pro Ser Phe Ser Pro Pro Pro Ser Leu Pro Pro Lys Met
          35                  40                  45            
 Cys Leu Pro Lys Cys Cys
      50                



      <210> 2641
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 2641
 Ala Ser Phe Phe Asn Phe Ser Ile Cys Ile Cys Lys Ile Ile Leu Glu
   1               5                  10                  15    
 Val Gly Pro Pro Val Gly His Pro Ala His Asp Asp Val Gly Gly Arg
              20                  25                  30        
 His Gly Pro Gly Gly Arg Gly Ser Arg Ser Pro Arg Ser Leu Gln Cys
          35                  40                  45            
 Ala Pro Gly Gly Gly Arg Arg Ser Gly Cys Pro Ala Gly Ser Ser Pro
      50                  55                  60                
 Ala Ser Thr Cys Pro Pro Ser Pro Gly Gly Ser Gly Ala Asp Arg Phe
  65                  70                  75                  80
 Gly Pro Ser Pro Pro Pro Pro Ser Arg Glu Ala Ala Pro Thr Ala Gly
                  85                  90                  95    
 Ala Ala Ala Ser Ser Thr Ser Ser Gly Ala Ser Cys Pro Pro Val Pro
             100                 105                 110        
 Ala Ser Ser Arg Trp Gly Val Arg Ser Arg Thr Arg Ser Gly Ser Gly
         115                 120                 125            
 Gly Glu Arg Glu Pro Arg Asp Arg Pro Ser Glu Arg Pro Arg Leu Val
     130                 135                 140                





      <210> 2642
      <211> 265
      <212> PRT
      <213> Homo sapiens


      <400> 2642
 Val Val Glu Phe Ala Asp Val Glu Lys Lys Gly Ala Gly Arg Thr Glu
   1               5                  10                  15    
 Phe Arg Tyr Pro Ser Tyr Val Gln His Ile Met Gly Asp Ile Phe Ser
              20                  25                  30        
 Gln Gly Phe Gly Pro Phe Arg Trp Val Cys Thr Ser Gly Asp Pro Gln
          35                  40                  45            
 Asp Leu Ala Val Thr Asp Glu Leu Ala Thr Ser Val Leu Glu Glu Ala
      50                  55                  60                
 Ile Ala Asp Gly Val Lys Val Ser Val Lys Leu Gln Tyr Met Asp Asn
  65                  70                  75                  80
 Ile Arg Trp Ile Arg Glu Ala Ala Arg His Arg Leu Val Val Gly Ser
                  85                  90                  95    
 Gln Ala Arg Ile Leu Tyr Ser Asp Gln Lys Gly Arg Val Ala Ile Ala
             100                 105                 110        
 Val Ala Ile Asn Gln Ala Ile Ala Cys Arg Arg Ile Lys Ala Pro Val
         115                 120                 125            
 Val Leu Ser Arg Asp His His Asp Val Ser Gly Thr Asp Ser Pro Phe
     130                 135                 140                
 Arg Glu Thr Ser Asn Ile Tyr Asp Gly Ser Ala Phe Cys Ala Asp Met
 145                 150                 155                 160
 Ala Val Gln Asn Phe Val Gly Asp Ala Cys Arg Gly Ala Thr Trp Val
                 165                 170                 175    
 Ala Leu His Asn Gly Gly Gly Val Gly Trp Gly Glu Val Ile Asn Gly
             180                 185                 190        
 Gly Phe Gly Leu Val Leu Asp Gly Thr Pro Glu Ala Glu Gly Arg Ala
         195                 200                 205            
 Arg Leu Met Leu Ser Trp Asp Val Ser Asn Gly Val Ala Arg Arg Cys
     210                 215                 220                
 Trp Ser Gly Asn Gln Lys Ala Tyr Glu Ile Ile Cys Gln Thr Met Gln
 225                 230                 235                 240
 Glu Asn Ser Thr Leu Val Val Thr Leu Pro His Lys Val Glu Asp Glu
                 245                 250                 255    
 Arg Val Leu Gln Gln Ala Leu Gln Leu
             260                 265



      <210> 2643
      <211> 833
      <212> PRT
      <213> Homo sapiens


      <400> 2643
 Gln Ile Ser Ser Gly Arg Glu Leu Arg Val Ile Gln Glu Ser Glu Ala
   1               5                  10                  15    
 Gly Asp Ala Gly Leu Pro Arg Val Glu Val Ile Leu Asp Cys Ser Asp
              20                  25                  30        
 Arg Gln Lys Thr Glu Gly Cys Arg Leu Gln Ala Gly Lys Glu Cys Val
          35                  40                  45            
 Asp Ser Pro Val Glu Gly Gly Gln Ser Glu Ala Pro Pro Ser Leu Val
      50                  55                  60                
 Ser Phe Ala Val Ser Ser Glu Gly Thr Glu Gln Gly Glu Asp Pro Arg
  65                  70                  75                  80
 Ser Glu Lys Asp His Ser Arg Pro His Lys His Arg Ala Arg His Ala
                  85                  90                  95    
 Arg Leu Arg Arg Ser Glu Ser Leu Ser Glu Lys Gln Val Lys Glu Ala
             100                 105                 110        
 Lys Ser Lys Cys Lys Ser Ile Ala Leu Leu Leu Thr Asp Ala Pro Asn
         115                 120                 125            
 Pro Asn Ser Lys Gly Val Leu Met Phe Lys Lys Arg Arg Arg Arg Ala
     130                 135                 140                
 Arg Lys Tyr Thr Leu Val Ser Tyr Gly Thr Gly Glu Leu Glu Arg Glu
 145                 150                 155                 160
 Ala Asp Glu Glu Glu Glu Gly Asp Lys Glu Asp Thr Cys Glu Val Ala
                 165                 170                 175    
 Phe Leu Gly Ala Ser Glu Ser Glu Val Asp Glu Glu Leu Leu Ser Asp
             180                 185                 190        
 Val Asp Asp Asn Thr Gln Val Val Asn Phe Asp Trp Asp Ser Gly Leu
         195                 200                 205            
 Val Asp Ile Glu Lys Lys Leu Asn Arg Gly Asp Lys Met Glu Met Leu
     210                 215                 220                
 Pro Asp Thr Thr Gly Lys Gly Ala Leu Met Phe Ala Lys Arg Arg Glu
 225                 230                 235                 240
 Arg Met Asp Gln Ile Thr Ala Gln Lys Glu Glu Asp Lys Val Gly Gly
                 245                 250                 255    
 Thr Pro Ser Arg Glu Gln Asp Ala Ala Gln Thr Asp Gly Leu Arg Thr
             260                 265                 270        
 Thr Thr Ser Tyr Gln Arg Lys Glu Glu Glu Ser Val Arg Thr Gln Ser
         275                 280                 285            
 Ser Val Ser Lys Ser Tyr Ile Glu Val Ser His Gly Leu Gly His Val
     290                 295                 300                
 Pro Gln Gln Asn Gly Phe Ser Gly Ala Ser Glu Thr Ala Asn Ile Gln
 305                 310                 315                 320
 Arg Met Val Pro Met Asn Arg Thr Ala Lys Pro Phe Pro Gly Ser Val
                 325                 330                 335    
 Asn Gln Pro Ala Thr Pro Phe Ser Pro Thr Arg Asn Met Thr Ser Pro
             340                 345                 350        
 Ile Ala Asp Phe Pro Ala Pro Pro Pro Tyr Ser Ala Val Thr Pro Pro
         355                 360                 365            
 Pro Asp Ala Phe Ser Arg Gly Val Ser Ser Pro Ile Ala Gly Pro Ala
     370                 375                 380                
 Gln Pro Pro Pro Trp Pro Gln Pro Ala Pro Trp Ser Gln Pro Ala Phe
 385                 390                 395                 400
 Tyr Asp Ser Ser Glu Arg Ile Ala Ser Arg Asp Glu Arg Ile Ser Val
                 405                 410                 415    
 Pro Ala Lys Arg Thr Gly Ile Leu Gln Glu Ala Lys Arg Arg Ser Thr
             420                 425                 430        
 Thr Lys Pro Met Phe Thr Phe Lys Glu Pro Lys Val Ser Pro Asn Pro
         435                 440                 445            
 Glu Leu Leu Ser Leu Leu Gln Asn Ser Glu Gly Lys Arg Gly Thr Gly
     450                 455                 460                
 Ala Gly Gly Asp Ser Gly Pro Glu Glu Asp Tyr Leu Ser Leu Gly Ala
 465                 470                 475                 480
 Glu Ala Cys Asn Phe Met Gln Ser Ser Ser Ala Lys Gln Lys Thr Pro
                 485                 490                 495    
 Pro Pro Val Ala Pro Lys Pro Ala Val Lys Ser Ser Ser Ser Gln Pro
             500                 505                 510        
 Val Thr Pro Val Ser Pro Val Trp Ser Pro Gly Val Ala Pro Thr Gln
         515                 520                 525            
 Pro Pro Ala Phe Pro Thr Ser Asn Pro Ser Lys Gly Thr Val Val Ser
     530                 535                 540                
 Ser Ile Lys Ile Ala Gln Pro Ser Tyr Pro Pro Ala Arg Pro Ala Ser
 545                 550                 555                 560
 Thr Leu Asn Val Ala Gly Pro Phe Lys Gly Pro Gln Ala Ala Val Ala
                 565                 570                 575    
 Ser Gln Asn Tyr Thr Pro Lys Pro Thr Val Ser Thr Pro Thr Val Asn
             580                 585                 590        
 Ala Val Gln Pro Gly Ala Val Gly Pro Ser Asn Glu Leu Pro Gly Met
         595                 600                 605            
 Ser Gly Arg Gly Ala Gln Leu Phe Ala Lys Arg Gln Ser Arg Met Glu
     610                 615                 620                
 Lys Tyr Val Val Asp Ser Asp Thr Val Gln Ala His Ala Ala Arg Ala
 625                 630                 635                 640
 Gln Ser Pro Thr Pro Ser Leu Pro Ala Ser Trp Lys Tyr Ser Ser Asn
                 645                 650                 655    
 Val Arg Ala Pro Pro Pro Val Ala Tyr Asn Pro Ile His Ser Pro Ser
             660                 665                 670        
 Tyr Pro Leu Ala Ala Leu Lys Ser Gln Pro Ser Ala Ala Gln Pro Ser
         675                 680                 685            
 Lys Met Gly Lys Lys Lys Gly Lys Lys Pro Leu Asn Ala Leu Asp Val
     690                 695                 700                
 Met Lys His Gln Pro Tyr Gln Leu Asn Ala Ser Leu Phe Thr Phe Gln
 705                 710                 715                 720
 Pro Pro Asp Ala Lys Asp Gly Leu Pro Gln Lys Ser Ser Val Lys Val
                 725                 730                 735    
 Asn Ser Ala Leu Ala Met Lys Gln Ala Leu Pro Pro Arg Pro Val Asn
             740                 745                 750        
 Ala Ala Ser Pro Thr Asn Val Gln Ala Ser Ser Val Tyr Ser Val Pro
         755                 760                 765            
 Ala Tyr Thr Ser Pro Pro Ser Phe Phe Ala Glu Ala Ser Ser Pro Val
     770                 775                 780                
 Ser Ala Ser Pro Val Pro Val Gly Ile Pro Thr Ser Pro Lys Gln Glu
 785                 790                 795                 800
 Ser Ala Ser Ser Ser Tyr Phe Val Ala Pro Arg Pro Lys Phe Ser Ala
                 805                 810                 815    
 Lys Lys Ser Gly Val Thr Ile Gln Val Trp Lys Pro Ser Val Val Glu
             820                 825                 830        
 Glu
    



      <210> 2644
      <211> 95
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(95)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2644
 Arg Ser Ser Asp Gly His Ala Ala Glu Thr Ser Arg Ser Cys Gln Leu
   1               5                  10                  15    
 His Xaa Val Ser Arg Ser Arg Asn His Pro Gly Pro Gln Pro Ser Gly
              20                  25                  30        
 Asn Thr Leu Arg Val Arg Gln Ser Leu Ser Pro Pro Asp Ser Arg Thr
          35                  40                  45            
 Leu Ala Ser Ala Ile Leu Ala Pro Pro Thr Pro Leu Ser Ser Phe Arg
      50                  55                  60                
 Ala Leu Ala Leu Gln Pro Gln Glu Glu Asn Arg Arg Glu Glu Glu Met
  65                  70                  75                  80
 Lys Glu Glu Gly Gln Val Leu Gly Ala Val Pro Leu Arg Thr Ser
                  85                  90                  95



      <210> 2645
      <211> 71
      <212> PRT
      <213> Homo sapiens


      <400> 2645
 Met Ala Thr His Pro Ser Leu Leu Val Cys Gln Val Gly Leu Leu Gly
   1               5                  10                  15    
 Ala Gln Val Pro Ser Val Arg Ala Gly Met Pro Gln Ser Arg Arg Gln
              20                  25                  30        
 Thr Glu Gly Ala Gln Gly Met Val Arg Asn Glu Glu Gly Gly Ser Leu
          35                  40                  45            
 Arg Leu Ser His His Gln Ala Cys Lys Ala Thr His Thr Gln Gln Trp
      50                  55                  60                
 Thr Leu Glu Val Thr Ala Gln
  65                  70    



      <210> 2646
      <211> 196
      <212> PRT
      <213> Homo sapiens


      <400> 2646
 Met Thr Ile His Ile Leu Ile Leu Leu Leu Leu Leu Ala Phe Ser Ala
   1               5                  10                  15    
 Gln Gly Asp Leu Asp Thr Ala Ala Arg Arg Gly Gln His Gln Val Pro
              20                  25                  30        
 Gln His Arg Gly His Val Cys Tyr Leu Gly Val Cys Arg Thr His Arg
          35                  40                  45            
 Leu Ala Glu Ile Ile Tyr Trp Ile Arg Cys Leu His Gln Gly Ala Leu
      50                  55                  60                
 Gly Glu Gly Gln Pro Arg Ala Pro Gly Pro Leu Gln Leu Trp Ala Pro
  65                  70                  75                  80
 Pro Val Ala Arg Gly Gly Ser Pro Ala Arg Phe Pro Gly Phe Arg Pro
                  85                  90                  95    
 Ala Ala Arg Gly Leu Ala Gln Cys Pro Ala Arg Trp Val Thr Ser Gly
             100                 105                 110        
 Thr Ala Arg Pro Leu Leu Gly Phe Ser Leu Pro Ile Trp Leu Gln Arg
         115                 120                 125            
 Asp Met Ala Glu Ala His Gln Ala Val Gly Phe Arg Pro Ser Leu Thr
     130                 135                 140                
 Ser Asp Gly Ala Glu Val Glu Leu Ser Ala Pro Val Leu Gln Glu Ile
 145                 150                 155                 160
 Tyr Leu Ser Gly Leu Arg Ser Trp Lys Arg His Leu Ser Arg Phe Trp
                 165                 170                 175    
 Val Arg Ser Gly Ala Gly Arg Phe Pro Ser Gly Asp Pro Gly Phe Cys
             180                 185                 190        
 Phe Arg Asp Val
         195    



      <210> 2647
      <211> 262
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(262)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2647
 Phe Gln Glu Ala Ala Val Gln Leu Tyr Ser His Ala Pro His Val Gln
   1               5                  10                  15    
 Leu Arg Leu Lys Ile Ser Pro Gly His Ser Pro Pro Ala Leu Gly Leu
              20                  25                  30        
 Ser Phe Pro Pro Gly Gln Gly Arg Gly Phe Ser Cys Gln Leu Leu Pro
          35                  40                  45            
 Ala Ser Phe Ser Trp Gly Ile Pro Gln Arg Pro Leu Pro Gln Arg Glu
      50                  55                  60                
 Pro Pro Gly Arg Thr Arg Thr Pro Ala Trp Ser Cys Ser Trp Gly Pro
  65                  70                  75                  80
 Ala Ile Pro Pro Val His Thr Leu Val Pro Ala Pro Ser Pro Gly Pro
                  85                  90                  95    
 Gly Ala Asp Arg Gly Gly Ser Gln Gly Pro Gly Leu Leu Val Gln Gly
             100                 105                 110        
 Leu Pro Leu Gly Ser Leu Ala Pro Xaa Ala Leu Gly Leu Pro Gly Ala
         115                 120                 125            
 Ser Ala Asp Thr Pro Val Pro Arg Arg Leu His Ser Gln Ala Cys Cys
     130                 135                 140                
 Ser His Gly Val Thr Gly Xaa Gly Met Gly Xaa Gly Asp Val Ser Pro
 145                 150                 155                 160
 Val Pro Val Pro Gln Gly Pro Leu Gly Trp His Leu Phe Arg Val Pro
                 165                 170                 175    
 Ala Gly Ser Gln Arg Ser Ser Pro Ile Pro His Gln Val Leu Gly Gly
             180                 185                 190        
 Thr Arg Gln Pro Leu Gly Pro Gly Pro Val Arg Lys Trp Thr Glu Leu
         195                 200                 205            
 Ala Gly Asp Thr Gly Asp Lys Lys Glu Ala Ser Ser Pro Lys Glu Leu
     210                 215                 220                
 Val Gly Pro Gln Arg Val Gly Gly Leu Ala Gly Thr Val Thr Leu Val
 225                 230                 235                 240
 Pro His Leu Cys Cys Gly Arg Arg Ala Pro Pro Gly Gly Leu Asp Gly
                 245                 250                 255    
 Ala Val Glu Ile Val Ala
             260        



      <210> 2648
      <211> 310
      <212> PRT
      <213> Homo sapiens


      <400> 2648
 Lys Ala Leu Cys Pro Cys Leu Pro Val Pro Leu Val His Gly Asn Val
   1               5                  10                  15    
 Glu Val Ala Gly Pro Arg Ser Gly Gly Ala Cys Pro Thr Leu Gly Leu
              20                  25                  30        
 Val Val Leu Phe Asn Pro Pro Gly Asn His Ala Ala Thr Leu Arg Ala
          35                  40                  45            
 His Gly Gln Pro Cys Thr Ala Leu Trp Arg Pro Leu Lys Pro Ser Pro
      50                  55                  60                
 Gln Gly Tyr Leu Glu Gly Ala Ala Arg Gly Ser Ala Ala Lys Arg Pro
  65                  70                  75                  80
 Leu Gln Arg Ala Leu Val Ser Leu Asp Pro Gly Leu Gly Val Leu Ala
                  85                  90                  95    
 Ala Thr Arg Leu Pro Gly Pro Val Ala Gly Gly Trp Glu Thr Gln Tyr
             100                 105                 110        
 Met Cys Cys Ser Ala Ala Ala Gly Ser Val Gly Cys Gln Val Ala Lys
         115                 120                 125            
 Gln His Val Gln Asp Gly Arg Lys Glu Arg Leu Glu Gly Phe Val Lys
     130                 135                 140                
 Thr Phe Glu Lys Glu Leu Ser Gly Asp Thr His Pro Gly Ile Tyr Ala
 145                 150                 155                 160
 Leu Asp Cys Glu Met Ser Tyr Thr Thr Tyr Gly Leu Glu Leu Thr Arg
                 165                 170                 175    
 Val Thr Val Val Asp Thr Asp Val His Val Val Tyr Asp Thr Phe Val
             180                 185                 190        
 Lys Pro Asp Asn Glu Ile Val Asp Tyr Asn Thr Arg Phe Ser Gly Val
         195                 200                 205            
 Thr Glu Ala Asp Leu Ala Asp Thr Ser Val Thr Leu Arg Asp Val Gln
     210                 215                 220                
 Ala Val Leu Leu Ser Met Phe Ser Ala Asp Thr Ile Leu Ile Gly His
 225                 230                 235                 240
 Ser Leu Glu Ser Asp Leu Leu Ala Leu Lys Val Ile His Ser Thr Val
                 245                 250                 255    
 Val Asp Thr Ser Val Leu Phe Pro His Arg Leu Gly Leu Pro Tyr Lys
             260                 265                 270        
 Arg Ser Leu Arg Asn Leu Met Ala Asp Tyr Leu Arg Gln Ile Ile Gln
         275                 280                 285            
 Asp Asn Val Asp Gly His Ser Ser Ser Glu Asp Ala Gly Ala Cys Met
     290                 295                 300                
 His Leu Val Ile Trp Lys
 305                 310



      <210> 2649
      <211> 126
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(126)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2649
 Gln Ser Pro Gln Glu His Phe His Pro Glu Cys Gly Arg Arg Asp Ile
   1               5                  10                  15    
 Leu Cys Gln Val Arg Gln Glu Ile Arg Trp Pro Asn Pro Gly Glu Val
              20                  25                  30        
 His His Leu Gly Leu Glu Ile Cys Pro Val Trp Ile Leu Gln Leu His
          35                  40                  45            
 Leu Ala Leu Arg Thr Arg Ala Pro Glu His Pro Leu Gln Val His Arg
      50                  55                  60                
 Pro Gly Gly Gly Ala Val Xaa Arg Gly Val Pro Pro Pro Leu Arg Leu
  65                  70                  75                  80
 Leu Gln Ala Cys Asp Gly Pro Glu Val Pro Ala Ala Gly Arg Pro Arg
                  85                  90                  95    
 Pro Ala Arg Ser Ser Pro Gly Gln Trp Pro Pro Xaa Pro Ala Ala Val
             100                 105                 110        
 Ala Pro Pro Val Thr Glu Arg Pro Pro Thr Pro Ser Ala Ala
         115                 120                 125    



      <210> 2650
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2650
 Arg Ala Met Glu Pro Leu Leu Leu Gly Arg Gly Leu Ile Val Tyr Leu
   1               5                  10                  15    
 Met Phe Leu Leu Leu Lys Phe Ser Lys Ala Ile Glu Ile Pro Ser Ser
              20                  25                  30        
 Gly Lys Val Lys Thr Phe Ser Ala Ile Leu Leu Ser Met Asp Ser Pro
          35                  40                  45            
 Phe Gln Ala Gly Gly Ile Phe Gly Thr Pro Pro Gly Leu Gly Ser Arg
      50                  55                  60                
 Ile Leu Ser Pro Ser Pro Met Val Ser Leu Gly Ser Cys Cys Thr His
  65                  70                  75                  80
 Arg Ser Pro Ile Cys Phe Ser Pro
                  85            



      <210> 2651
      <211> 187
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(187)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2651
 Met Ala Glu Arg Ala Ala Gly Gly Gln Leu Pro Ser Gln Gly Pro Val
   1               5                  10                  15    
 Gln Leu Pro Ser Thr Arg Lys Glu Lys Asp Glu Gln Thr Glu Asn Gln
              20                  25                  30        
 Gln Leu Phe Phe Ile Arg Gln Arg Thr Glu Ser Pro Gly Lys Ala Arg
          35                  40                  45            
 Pro Pro Asn Leu Glu Thr Gln Thr Ser Gly Phe Gln Glu Pro Gln Leu
      50                  55                  60                
 Thr Gly Ala Glu Pro Leu Arg Gly Gln Cys His Gly Leu Glu Leu Pro
  65                  70                  75                  80
 Leu Met Asn Phe Trp Arg Cys His Leu Asp Lys Thr Asn Leu Arg Leu
                  85                  90                  95    
 Lys Glu Glu Leu Lys Ala Glu Lys Lys Ser Gly Phe Trp Asp Asn Leu
             100                 105                 110        
 Val Leu Lys Gln Asn Ile Gln Ser Lys Lys Pro Asp Glu Ile Glu Gly
         115                 120                 125            
 Trp Glu Pro Pro Lys Leu Ala Leu Glu Asp Ile Ser Ala Asp Pro Glu
     130                 135                 140                
 Asp Thr Val Gly Gly His Pro Ser Trp Ser Gly Trp Glu Asp Asp Ala
 145                 150                 155                 160
 Lys Gly Ser Thr Lys Tyr Thr Ser Leu Ala Ser Ser Ala Asn Ser Ser
                 165                 170                 175    
 Arg Trp Ser Leu Arg Ala Ala Gly Lys Ala Xaa
             180                 185        



      <210> 2652
      <211> 175
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(175)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2652
 Phe Arg Leu Gly Arg Lys Pro Arg Xaa Gly Gly Val Met Xaa Pro Val
   1               5                  10                  15    
 Trp Ser Arg Gly Glu Pro Gly Ser Val Gly Ala Glu Ala Gly Arg Ser
              20                  25                  30        
 Xaa Ser Ala Pro Arg Arg Leu Leu His His Pro Ala Ala Gly Leu Ala
          35                  40                  45            
 Thr Gly Leu Ser Ala Ser Gly Arg Arg Ser Ala Arg Trp Lys Met Glu
      50                  55                  60                
 Arg Ala Ser Gly Leu Ser Pro Gly Gly Gly Leu Gly Ala Thr Ser Arg
  65                  70                  75                  80
 Gln Met Ser Pro Gly Thr Gln Leu Ala Asn Pro Pro Asp His Gly Asp
                  85                  90                  95    
 Lys Asp Cys Leu Gly Arg Ile Ser Pro Gly Ser Gly Lys Gln Ile Gln
             100                 105                 110        
 Ala Ala Gly Gln Leu Pro Gly Pro Pro Thr Ser Leu Ala Pro Ala Gln
         115                 120                 125            
 Gly Arg Leu Arg Ser Leu Thr Pro Trp Gly Leu Gln Thr Pro Glu His
     130                 135                 140                
 Ser Glu Pro Glu Gly Ile Gly His Leu Gln Ala Ala Thr Glu Ala Val
 145                 150                 155                 160
 Leu Pro His Ser Thr Gln Asn Leu Ile Thr Lys Arg Asn Leu Met
                 165                 170                 175



      <210> 2653
      <211> 131
      <212> PRT
      <213> Homo sapiens


      <400> 2653
 Ala Ala Tyr Thr Leu Leu Leu His Ala Glu Leu Leu Gln Trp Ser Asp
   1               5                  10                  15    
 Lys Pro Cys Val Pro His Leu Leu Gln Arg Asp Ser Tyr Tyr Val Tyr
              20                  25                  30        
 Thr Gln Gln Glu Leu Lys Glu Lys Leu Tyr Gln Glu Ile Ile Ser Tyr
          35                  40                  45            
 Phe Asp Lys Gly Lys Met Trp Glu Lys Ala Ile Lys Leu Ser Lys Glu
      50                  55                  60                
 Leu Ala Glu Thr Tyr Glu Ser Lys Val Phe Asp Tyr Glu Gly Leu Gly
  65                  70                  75                  80
 Asn Leu Leu Lys Lys Arg Ala Ser Phe Tyr Glu Asn Ile Ile Lys Ala
                  85                  90                  95    
 Met Ser Pro Gln Pro Glu Tyr Phe Ala Val Gly Tyr Tyr Gly Gln Gly
             100                 105                 110        
 Phe Pro Ser Phe Leu Arg Asn Lys Ile Phe Ile Tyr Arg Gly Lys Glu
         115                 120                 125            
 Tyr Glu Arg
     130    



      <210> 2654
      <211> 168
      <212> PRT
      <213> Homo sapiens


      <400> 2654
 Met Pro Leu Thr His Pro Asn His Gly Pro Asp Thr Leu Gln Arg Trp
   1               5                  10                  15    
 Thr Ser Ser Gln Thr Pro Thr Ser Leu Ser Ser Lys Leu Asn Pro Glu
              20                  25                  30        
 Pro Glu Ala Asp Ala Ala Ser Ile Leu Ile Ala Thr Ser Ile Leu Tyr
          35                  40                  45            
 Lys Gln Ser Asp Pro Tyr Leu Asp Ile Leu Ala Arg Val Tyr Gly Pro
      50                  55                  60                
 Pro Thr Ala Ala Glu Glu Asn Leu Lys Cys Leu Lys Glu Gln Gly Gln
  65                  70                  75                  80
 Ala His Leu Arg His Phe Leu Leu Cys Lys Met Ala Ala Pro Ile Ala
                  85                  90                  95    
 Val Val Leu Thr Ala Ala Met Phe Glu Asn Trp Thr His Arg Arg Gln
             100                 105                 110        
 Trp Gln Val Phe Glu Pro Gly Ala Arg Glu Glu Glu Lys Ser Leu Lys
         115                 120                 125            
 Ser Pro Arg Phe Leu Ala Leu Lys Val Leu Arg Lys Gly Ala Asp Phe
     130                 135                 140                
 Gln Arg Leu Arg Leu Tyr Gln Ala Asn Met Gly Gln Ala Lys Leu Pro
 145                 150                 155                 160
 Leu Ala Leu Phe His Pro Leu Cys
                 165            



      <210> 2655
      <211> 343
      <212> PRT
      <213> Homo sapiens


      <400> 2655
 Ala Leu Met Asn Lys Cys Ala Val Ser Thr Gly Arg Gln Arg Cys Ser
   1               5                  10                  15    
 Val Met Trp Ala Arg Ala Cys Ser Val Phe Cys Val Leu Thr Leu Arg
              20                  25                  30        
 Asn Thr Gly Ala Gln Lys His Trp Leu Thr Glu Gly Ala Ala Lys Glu
          35                  40                  45            
 His Cys Val Ser Asp Asp Ser Glu His Phe Glu Ser Trp Arg Ala Ala
      50                  55                  60                
 Gln Leu Phe Glu Ser Val Asp Ala Glu Pro Met Asn Met Glu Ser Gln
  65                  70                  75                  80
 Leu His Phe Ile Met Pro Lys Ala Leu Arg Thr Lys Lys Ala Ala Ser
                  85                  90                  95    
 Asp Ser Ser Lys Glu Gln Val Ala Asn Ser Arg Glu Ser Ser Pro Ser
             100                 105                 110        
 Pro Lys Glu Val Asn Asp Ser Pro Arg Ala Ala Thr Lys Ser Pro Glu
         115                 120                 125            
 Ser Gln Asn Leu Ile Asp Gly Thr Lys Lys Pro Ser Leu Lys Gln Pro
     130                 135                 140                
 Asp Ser Pro Arg Asn Ile Ser Ser Asp Asn Ser Ser Lys Gly Thr Pro
 145                 150                 155                 160
 Ser Ser Pro Ala Gly Ser Thr Thr Ala Ile Pro Lys Val Arg Ile Lys
                 165                 170                 175    
 Thr Ile Lys Thr Ser Ser Gly Glu Ile Lys Arg Thr Glu Thr Arg Val
             180                 185                 190        
 Phe Pro Glu Val Asp Leu Asp Ser Gly Lys Lys Pro Ser Glu Gln Met
         195                 200                 205            
 Val Ser Val Met Ala Ser Val Thr Ser Leu Leu Ser Ser Pro Ala Ser
     210                 215                 220                
 Ala Ala Ala Leu Ser Ser Pro Pro Arg Val Pro Leu Gln Ser Ala Val
 225                 230                 235                 240
 Val Thr Asn Ala Val Phe Pro Ala Glu Pro Thr Pro Lys Gln Val Thr
                 245                 250                 255    
 Ile Lys Pro Val Ala Thr Ala Phe Leu Pro Val Ser Ala Val Lys Thr
             260                 265                 270        
 Ala Gly Ser Gln Val Ile Asn Leu Lys Leu Ala Asn Asn Thr Thr Val
         275                 280                 285            
 Lys Ala Thr Val Ile Pro Ala Ala Ser Val Gln Ser Ala Ser Ser Ile
     290                 295                 300                
 Ile Ile Lys Ala Ala Asn Ala Ile Gln Glu Gln Ala Val Met Met Pro
 305                 310                 315                 320
 Ala Ser Ser Leu Ala Asn Ala Lys Leu Val Pro Lys Thr Val His Leu
                 325                 330                 335    
 Ala Asn Leu Asn Leu Leu Ala
             340            



      <210> 2656
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 2656
 Lys Gly Ala Gly Val Leu Gln Thr Phe Gly Ser Ser Glu Ser Val Phe
   1               5                  10                  15    
 Cys Ile Asp Val Asp Arg Glu Leu Leu Ile Phe Ala Tyr Gln Asn Ile
              20                  25                  30        
 Leu Leu Phe Leu Lys Asn Lys Arg Ala Leu Ile Leu Glu Thr Thr Cys
          35                  40                  45            
 Phe Gly Trp Val Gly Thr Val Lys Arg Thr
      50                  55            



      <210> 2657
      <211> 245
      <212> PRT
      <213> Homo sapiens


      <400> 2657
 Phe Arg Gly Glu Ile Ala Glu Asn Leu Pro Glu Gln Asp Ile Leu Ile
   1               5                  10                  15    
 Gln Ser Val Cys Glu Thr Met Val Pro Lys Leu Val Ala Glu Asp Ile
              20                  25                  30        
 Pro Leu Leu Phe Ser Leu Leu Ser Asp Val Phe Pro Gly Val Gln Tyr
          35                  40                  45            
 His Arg Gly Glu Met Thr Ala Leu Arg Glu Glu Leu Lys Lys Val Cys
      50                  55                  60                
 Gln Glu Met Tyr Leu Thr Tyr Gly Asp Gly Glu Glu Val Gly Gly Met
  65                  70                  75                  80
 Trp Val Glu Lys Val Leu Gln Leu Tyr Gln Ile Thr Gln Ile Asn His
                  85                  90                  95    
 Gly Leu Met Met Val Gly Pro Ser Gly Ser Gly Lys Ser Met Ala Trp
             100                 105                 110        
 Arg Val Leu Leu Lys Ala Leu Glu Arg Leu Glu Gly Val Glu Gly Val
         115                 120                 125            
 Ala His Ile Ile Asp Pro Lys Ala Ile Ser Lys Asp His Leu Tyr Gly
     130                 135                 140                
 Thr Leu Asp Pro Asn Thr Arg Glu Trp Thr Asp Gly Leu Phe Thr His
 145                 150                 155                 160
 Val Leu Arg Lys Ile Ile Asp Ser Val Arg Gly Glu Leu Gln Lys Arg
                 165                 170                 175    
 Gln Trp Ile Val Phe Asp Gly Asp Val Asp Pro Glu Trp Val Glu Asn
             180                 185                 190        
 Leu Asn Ser Val Leu Asp Asp Asn Lys Leu Leu Thr Leu Pro Asn Gly
         195                 200                 205            
 Glu Arg Leu Ser Leu Pro Pro Asn Val Arg Ile Met Phe Glu Val Gln
     210                 215                 220                
 Asp Leu Lys Tyr Ala Thr Leu Ala Thr Val Ser Arg Cys Gly Met Val
 225                 230                 235                 240
 Trp Phe Ser Glu Asp
                 245



      <210> 2658
      <211> 42
      <212> PRT
      <213> Homo sapiens


      <400> 2658
 Met Lys Ile Ala Ala Leu Leu Gly Cys Met Met Met Ala Ala Arg Cys
   1               5                  10                  15    
 Gly Thr Leu Ser Ala Met Arg Asp Leu Ser Phe Ser Asp Glu Asn Arg
              20                  25                  30        
 Arg Leu Ala Val Gly Thr Ala Ala Ala Ala
          35                  40        



      <210> 2659
      <211> 298
      <212> PRT
      <213> Homo sapiens


      <400> 2659
 Met Pro Gly Pro Met Ser Leu Trp Leu Leu Leu Leu Val Leu Pro Leu
   1               5                  10                  15    
 Ser Leu Glu His Ser Asp Leu Arg Ile Cys Phe Pro Gly Gln Val Val
              20                  25                  30        
 Ser Met Glu Ser Ser Ser Thr Gly Phe Ile Trp Thr Asp Val Arg Ala
          35                  40                  45            
 Trp Gln Thr Ser Asn Arg His Val Ser Ser Trp Arg Glu Pro Arg His
      50                  55                  60                
 Ser Arg Met Pro Pro Gly Ala Gly Leu Met Glu Arg Ile Gln Ala Ile
  65                  70                  75                  80
 Ala Gln Asn Val Ser Asp Ile Ala Val Lys Val Asp Gln Ile Leu Arg
                  85                  90                  95    
 His Ser Leu Leu Leu His Ser Lys Val Ser Glu Gly Arg Arg Asp Gln
             100                 105                 110        
 Cys Glu Ala Pro Ser Asp Pro Lys Phe Pro Asp Cys Ser Gly Lys Val
         115                 120                 125            
 Glu Trp Met Arg Ala Arg Trp Thr Ser Asp Pro Cys Tyr Ala Phe Phe
     130                 135                 140                
 Gly Val Asp Gly Thr Glu Cys Ser Phe Leu Ile Tyr Leu Ser Glu Val
 145                 150                 155                 160
 Glu Trp Phe Cys Pro Pro Leu Pro Trp Arg Asn Gln Thr Ala Ala Gln
                 165                 170                 175    
 Arg Ala Pro Lys Pro Leu Pro Lys Val Gln Ala Val Phe Arg Ser Asn
             180                 185                 190        
 Leu Ser His Leu Leu Asp Leu Met Gly Ser Gly Lys Glu Ser Leu Ile
         195                 200                 205            
 Phe Met Lys Lys Arg Thr Lys Arg Leu Thr Ala Gln Trp Ala Leu Ala
     210                 215                 220                
 Ala Gln Arg Leu Ala Gln Lys Leu Gly Ala Thr Gln Arg Asp Gln Lys
 225                 230                 235                 240
 Gln Ile Leu Val His Ile Gly Phe Leu Thr Glu Glu Ser Gly Asp Val
                 245                 250                 255    
 Phe Ser Pro Arg Val Leu Lys Gly Gly Pro Leu Gly Glu Met Val Gln
             260                 265                 270        
 Trp Ala Asp Ile Leu Thr Ala Leu Tyr Val Leu Gly His Gly Leu Arg
         275                 280                 285            
 Val Thr Val Ser Leu Lys Glu Leu Gln Arg
     290                 295            



      <210> 2660
      <211> 4899
      <212> PRT
      <213> Homo sapiens


      <400> 2660
 Ala Ala Ala Val Ser Ala Arg Arg Ala Ala Ala Gly Gly Ser Arg Gly
   1               5                  10                  15    
 Ala Gly Gly Trp Gly Thr Ala Asp Ala Ser Gly Ala Met Ala Glu Gly
              20                  25                  30        
 Gly Glu Gly Gly Glu Asp Glu Ile Gln Phe Leu Arg Thr Glu Asp Glu
          35                  40                  45            
 Val Val Leu Gln Cys Ile Ala Thr Ile His Lys Glu Gln Arg Lys Phe
      50                  55                  60                
 Cys Leu Ala Ala Glu Gly Leu Gly Asn Arg Leu Cys Phe Leu Glu Pro
  65                  70                  75                  80
 Thr Ser Glu Ala Lys Tyr Ile Pro Pro Asp Leu Cys Val Cys Asn Phe
                  85                  90                  95    
 Val Leu Glu Gln Ser Leu Ser Val Arg Ala Leu Gln Glu Met Leu Ala
             100                 105                 110        
 Asn Thr Gly Glu Asn Gly Gly Glu Gly Ala Ala Gln Gly Gly Gly His
         115                 120                 125            
 Arg Thr Leu Leu Tyr Gly His Ala Val Leu Leu Arg His Ser Phe Ser
     130                 135                 140                
 Gly Met Tyr Leu Thr Cys Leu Thr Thr Ser Arg Ser Gln Thr Asp Lys
 145                 150                 155                 160
 Leu Ala Phe Asp Val Gly Leu Arg Glu His Ala Thr Gly Glu Ala Cys
                 165                 170                 175    
 Trp Trp Thr Ile His Pro Ala Ser Lys Gln Arg Ser Glu Gly Glu Lys
             180                 185                 190        
 Val Arg Ile Gly Asp Asp Leu Ile Leu Val Ser Val Ser Ser Glu Arg
         195                 200                 205            
 Tyr Leu His Leu Ser Val Ser Asn Gly Asn Ile Gln Val Asp Ala Ser
     210                 215                 220                
 Phe Met Gln Thr Leu Trp Asn Val His Pro Thr Cys Ser Gly Ser Ser
 225                 230                 235                 240
 Ile Glu Glu Gly Tyr Leu Leu Gly Gly His Val Val Arg Leu Phe His
                 245                 250                 255    
 Gly His Asp Glu Cys Leu Thr Ile Pro Ser Thr Asp Gln Asn Asp Ser
             260                 265                 270        
 Gln His Arg Arg Ile Phe Tyr Glu Ala Gly Gly Ala Gly Thr Arg Ala
         275                 280                 285            
 Arg Ser Leu Trp Arg Val Glu Pro Leu Arg Ile Ser Trp Ser Gly Ser
     290                 295                 300                
 Asn Ile Arg Trp Gly Gln Ala Phe Arg Leu Arg His Leu Thr Thr Gly
 305                 310                 315                 320
 His Tyr Leu Ala Leu Thr Glu Asp Gln Gly Leu Ile Leu Gln Asp Arg
                 325                 330                 335    
 Ala Lys Ser Asp Thr Lys Ser Thr Ala Phe Ser Phe Arg Ala Ser Lys
             340                 345                 350        
 Glu Leu Lys Glu Lys Leu Asp Ser Ser His Lys Arg Asp Ile Glu Gly
         355                 360                 365            
 Met Gly Val Pro Glu Ile Lys Tyr Gly Asp Ser Val Cys Phe Val Gln
     370                 375                 380                
 His Ile Ala Ser Gly Leu Trp Val Thr Tyr Lys Ala Gln Asp Ala Lys
 385                 390                 395                 400
 Thr Ser Arg Leu Gly Pro Leu Lys Arg Lys Val Ile Leu His Gln Glu
                 405                 410                 415    
 Gly His Met Asp Asp Gly Leu Thr Leu Gln Arg Cys Gln Arg Glu Glu
             420                 425                 430        
 Ser Gln Ala Ala Arg Ile Ile Arg Asn Thr Thr Ala Leu Phe Ser Gln
         435                 440                 445            
 Phe Val Ser Gly Asn Asn Arg Thr Ala Ala Pro Ile Thr Leu Pro Ile
     450                 455                 460                
 Glu Glu Val Leu Gln Thr Leu Gln Asp Leu Ile Ala Tyr Phe Gln Pro
 465                 470                 475                 480
 Pro Glu Glu Glu Met Arg His Glu Asp Lys Gln Asn Lys Leu Arg Ser
                 485                 490                 495    
 Leu Lys Asn Arg Gln Asn Leu Phe Lys Glu Glu Gly Met Leu Ala Leu
             500                 505                 510        
 Val Leu Asn Cys Ile Asp Arg Leu Asn Val Tyr Asn Ser Val Ala His
         515                 520                 525            
 Phe Ala Gly Ile Ala Arg Glu Glu Ser Gly Met Ala Trp Lys Glu Ile
     530                 535                 540                
 Leu Asn Leu Leu Tyr Lys Leu Leu Ala Ala Leu Ile Arg Gly Asn Arg
 545                 550                 555                 560
 Asn Asn Cys Ala Gln Phe Ser Asn Asn Leu Asp Trp Leu Ile Ser Lys
                 565                 570                 575    
 Leu Asp Arg Leu Glu Ser Ser Ser Gly Ile Leu Glu Val Leu His Cys
             580                 585                 590        
 Ile Leu Thr Glu Ser Pro Glu Ala Leu Asn Leu Ile Ala Glu Gly His
         595                 600                 605            
 Ile Lys Ser Ile Ile Ser Leu Leu Asp Lys His Gly Arg Asn His Lys
     610                 615                 620                
 Val Leu Asp Ile Leu Cys Ser Leu Cys Leu Cys Asn Gly Val Ala Val
 625                 630                 635                 640
 Arg Ala Asn Gln Asn Leu Ile Cys Asp Asn Leu Leu Pro Arg Arg Asn
                 645                 650                 655    
 Leu Leu Leu Gln Thr Arg Leu Ile Asn Asp Val Thr Ser Ile Arg Pro
             660                 665                 670        
 Asn Ile Phe Leu Gly Val Ala Glu Gly Ser Ala Gln Tyr Lys Lys Trp
         675                 680                 685            
 Tyr Phe Glu Leu Ile Ile Asp Gln Val Asp Pro Phe Leu Thr Ala Glu
     690                 695                 700                
 Pro Thr His Leu Arg Val Gly Trp Ala Ser Ser Ser Gly Tyr Ala Pro
 705                 710                 715                 720
 Tyr Pro Gly Gly Gly Glu Gly Trp Gly Gly Asn Gly Val Gly Asp Asp
                 725                 730                 735    
 Leu Tyr Ser Tyr Gly Phe Asp Gly Leu His Leu Trp Ser Gly Arg Ile
             740                 745                 750        
 Pro Arg Ala Val Ala Ser Ile Asn Gln His Leu Leu Arg Ser Asp Asp
         755                 760                 765            
 Val Gly Lys Leu Leu Pro Gly Pro Arg Gly Cys Pro Ala Ser His Ser
     770                 775                 780                
 Ala Ser Met Gly Ser Pro Cys Arg Gly Cys Leu Glu Asn Phe Asn Thr
 785                 790                 795                 800
 Asp Gly Leu Phe Phe Pro Val Met Ser Phe Ser Ala Gly Val Lys Val
                 805                 810                 815    
 Arg Phe Leu Met Gly Gly Arg His Gly Glu Phe Lys Phe Leu Pro Pro
             820                 825                 830        
 Ser Gly Tyr Ala Pro Cys Tyr Glu Ala Leu Leu Pro Lys Glu Lys Met
         835                 840                 845            
 Arg Leu Glu Pro Val Lys Glu Tyr Lys Arg Asp Ala Asp Gly Ile Arg
     850                 855                 860                
 Asp Leu Leu Gly Thr Thr Gln Phe Leu Ser Gln Ala Ser Phe Ile Pro
 865                 870                 875                 880
 Cys Pro Val Asp Thr Ser Gln Val Ile Leu Pro Pro His Leu Glu Lys
                 885                 890                 895    
 Ile Arg Asp Arg Leu Ala Glu Asn Ile His Glu Leu Trp Gly Met Asn
             900                 905                 910        
 Lys Ile Glu Leu Gly Trp Thr Phe Gly Lys Ile Arg Asp Asp Asn Lys
         915                 920                 925            
 Arg Gln His Pro Cys Leu Val Glu Phe Ser Lys Leu Pro Glu Thr Glu
     930                 935                 940                
 Lys Asn Tyr Asn Leu Gln Met Ser Thr Glu Thr Leu Lys Thr Leu Leu
 945                 950                 955                 960
 Thr Leu Gly Cys His Ile Ala His Val Asn Pro Ala Ala Glu Glu Asp
                 965                 970                 975    
 Leu Lys Lys Val Lys Leu Pro Lys Asn Tyr Met Met Ser Asn Gly Tyr
             980                 985                 990        
 Lys Pro Ala Pro Leu Asp Leu Ser Asp Val Lys Leu Leu Pro Pro Gln
         995                1000                1005            
 Glu Ile Leu Val Asp Lys Leu Ala Glu Asn Ala His Asn Val Trp Ala
    1010                1015                1020                
 Lys Asp Arg Ile Lys Gln Gly Trp Thr Tyr Gly Ile Gln Gln Asp Leu
1025                1030                1035                1040
 Lys Asn Lys Arg Asn Pro Arg Leu Val Pro Tyr Ala Leu Leu Asp Glu
                1045                1050                1055    
 Arg Thr Lys Lys Ser Asn Arg Asp Ser Leu Arg Glu Ala Val Arg Thr
            1060                1065                1070        
 Phe Val Gly Tyr Gly Tyr Asn Ile Glu Pro Ser Asp Gln Glu Leu Ala
        1075                1080                1085            
 Asp Ser Ala Val Glu Lys Val Ser Ile Asp Lys Ile Arg Phe Phe Arg
    1090                1095                1100                
 Val Glu Arg Ser Tyr Pro Val Arg Ser Gly Lys Trp Tyr Phe Glu Phe
1105                1110                1115                1120
 Glu Val Val Thr Gly Gly Asp Met Arg Val Gly Trp Ala Arg Pro Gly
                1125                1130                1135    
 Cys Arg Pro Asp Val Glu Leu Gly Ala Asp Asp Gln Ala Phe Val Phe
            1140                1145                1150        
 Glu Gly Asn Arg Gly Gln Arg Trp His Gln Gly Ser Gly Tyr Phe Gly
        1155                1160                1165            
 Arg Thr Trp Gln Pro Gly Asp Val Val Gly Cys Met Ile Asn Leu Asp
    1170                1175                1180                
 Asp Ala Ser Met Ile Phe Thr Leu Asn Gly Glu Leu Leu Ile Thr Asn
1185                1190                1195                1200
 Lys Gly Ser Glu Leu Ala Phe Ala Asp Tyr Glu Ile Glu Asn Gly Phe
                1205                1210                1215    
 Val Pro Ile Cys Cys Leu Gly Leu Ser Gln Ile Gly Arg Met Asn Leu
            1220                1225                1230        
 Gly Thr Asp Ala Ser Thr Phe Lys Phe Tyr Thr Met Cys Gly Leu Gln
        1235                1240                1245            
 Glu Gly Phe Glu Pro Phe Ala Val Asn Met Asn Arg Asp Val Ala Met
    1250                1255                1260                
 Trp Phe Ser Lys Arg Leu Pro Thr Phe Val Asn Val Pro Lys Asp His
1265                1270                1275                1280
 Pro His Ile Glu Val Met Arg Ile Asp Gly Thr Met Asp Ser Pro Pro
                1285                1290                1295    
 Cys Leu Lys Val Thr His Lys Thr Phe Gly Thr Gln Asn Ser Asn Ala
            1300                1305                1310        
 Asp Met Ile Tyr Cys Arg Leu Ser Met Pro Val Glu Cys His Ser Ser
        1315                1320                1325            
 Phe Ser His Ser Pro Cys Leu Asp Ser Glu Ala Phe Gln Lys Arg Lys
    1330                1335                1340                
 Gln Met Gln Glu Ile Leu Ser His Thr Thr Thr Gln Cys Tyr Tyr Ala
1345                1350                1355                1360
 Ile Arg Ile Phe Gly Gly Gln Asp Pro Ser Cys Val Trp Val Gly Trp
                1365                1370                1375    
 Val Thr Pro Asp Tyr His Leu Tyr Ser Glu Lys Phe Asp Leu Asn Lys
            1380                1385                1390        
 Asn Cys Thr Val Thr Val Thr Leu Gly Asp Glu Arg Gly Arg Val His
        1395                1400                1405            
 Glu Ser Val Lys Arg Ser Asn Cys Tyr Met Val Trp Gly Gly Asp Ile
    1410                1415                1420                
 Val Ala Ser Ser Gln Arg Ser Asn Arg Ser Asn Val Asp Leu Glu Ile
1425                1430                1435                1440
 Gly Cys Leu Val Asp Leu Ala Met Gly Met Leu Ser Phe Ser Ala Asn
                1445                1450                1455    
 Gly Lys Glu Leu Gly Thr Cys Tyr Gln Val Glu Pro Asn Thr Lys Val
            1460                1465                1470        
 Phe Pro Ala Val Phe Leu Gln Pro Thr Ser Thr Ser Leu Phe Gln Phe
        1475                1480                1485            
 Glu Leu Gly Lys Leu Lys Asn Ala Met Pro Leu Ser Ala Ala Ile Phe
    1490                1495                1500                
 Arg Ser Glu Glu Glu Asn Pro Val Pro Gln Cys Pro Pro Arg Leu Asp
1505                1510                1515                1520
 Val Gln Thr Ile Gln Pro Val Leu Trp Ser Arg Met Pro Asn Ser Phe
                1525                1530                1535    
 Leu Lys Val Glu Thr Glu Arg Val Ser Glu Arg His Gly Trp Val Val
            1540                1545                1550        
 Gln Cys Leu Glu Pro Leu Gln Met Met Ala Leu His Ile Pro Glu Glu
        1555                1560                1565            
 Asn Arg Cys Val Asp Ile Leu Glu Leu Cys Glu Gln Glu Asp Leu Met
    1570                1575                1580                
 Arg Phe His Tyr His Thr Leu Arg Leu Tyr Ser Ala Val Cys Ala Leu
1585                1590                1595                1600
 Gly Asn Ser Arg Val Ala Tyr Ala Leu Cys Ser His Val Asp Leu Ser
                1605                1610                1615    
 Gln Leu Phe Tyr Ala Ile Asp Asn Lys Tyr Leu Pro Gly Leu Leu Arg
            1620                1625                1630        
 Ser Gly Phe Tyr Asp Leu Leu Ile Ser Ile His Leu Ala Ser Ala Lys
        1635                1640                1645            
 Glu Arg Lys Leu Met Met Lys Asn Glu Tyr Ile Ile Pro Ile Thr Ser
    1650                1655                1660                
 Thr Thr Arg Asn Ile Cys Leu Phe Pro Asp Glu Ser Lys Arg His Gly
1665                1670                1675                1680
 Leu Pro Gly Val Gly Leu Arg Thr Cys Leu Lys Pro Gly Phe Arg Phe
                1685                1690                1695    
 Ser Thr Pro Cys Phe Val Val Thr Gly Glu Asp His Gln Lys Gln Ser
            1700                1705                1710        
 Pro Glu Ile Pro Leu Glu Ser Leu Arg Thr Lys Ala Leu Ser Met Leu
        1715                1720                1725            
 Thr Glu Ala Val Gln Cys Ser Gly Ala His Ile Arg Asp Pro Val Gly
    1730                1735                1740                
 Gly Ser Val Glu Phe Gln Phe Val Pro Val Leu Lys Leu Ile Gly Thr
1745                1750                1755                1760
 Leu Leu Val Met Gly Val Phe Asp Asp Asp Asp Val Arg Gln Ile Leu
                1765                1770                1775    
 Leu Leu Ile Asp Pro Ser Val Phe Gly Glu His Ser Ala Gly Thr Glu
            1780                1785                1790        
 Glu Gly Ala Glu Lys Glu Glu Val Thr Gln Val Glu Glu Lys Ala Val
        1795                1800                1805            
 Glu Ala Gly Glu Lys Ala Gly Lys Glu Ala Pro Val Lys Gly Leu Leu
    1810                1815                1820                
 Gln Thr Arg Leu Pro Glu Ser Val Lys Leu Gln Met Cys Glu Leu Leu
1825                1830                1835                1840
 Ser Tyr Leu Cys Asp Cys Glu Leu Gln His Arg Val Glu Ala Ile Val
                1845                1850                1855    
 Ala Phe Gly Asp Ile Tyr Val Ser Lys Leu Gln Ala Asn Gln Lys Phe
            1860                1865                1870        
 Arg Tyr Asn Glu Leu Met Gln Ala Leu Asn Met Ser Ala Ala Leu Thr
        1875                1880                1885            
 Ala Arg Lys Thr Lys Glu Phe Arg Ser Pro Pro Gln Glu Gln Ile Asn
    1890                1895                1900                
 Met Leu Leu Asn Phe Gln Leu Gly Glu Asn Cys Pro Cys Pro Glu Glu
1905                1910                1915                1920
 Ile Arg Glu Glu Leu Tyr Asp Phe His Glu Asp Leu Leu Leu His Cys
                1925                1930                1935    
 Gly Val Pro Leu Glu Glu Glu Glu Glu Glu Glu Glu Asp Thr Ser Trp
            1940                1945                1950        
 Thr Gly Lys Leu Cys Ala Leu Val Tyr Lys Ile Lys Gly Pro Pro Lys
        1955                1960                1965            
 Pro Glu Lys Glu Gln Pro Thr Glu Glu Glu Glu Arg Cys Pro Thr Thr
    1970                1975                1980                
 Leu Lys Glu Leu Ile Ser Gln Thr Met Ile Cys Trp Ala Gln Glu Asp
1985                1990                1995                2000
 Gln Ile Gln Asp Ser Glu Leu Val Arg Met Met Phe Asn Leu Leu Arg
                2005                2010                2015    
 Arg Gln Tyr Asp Ser Ile Gly Glu Leu Leu Gln Ala Leu Arg Lys Thr
            2020                2025                2030        
 Tyr Thr Ile Ser His Thr Ser Val Ser Asp Thr Ile Asn Leu Leu Ala
        2035                2040                2045            
 Ala Leu Gly Gln Ile Arg Ser Leu Leu Ser Val Arg Met Gly Lys Glu
    2050                2055                2060                
 Glu Glu Leu Leu Met Ile Asn Gly Leu Gly Asp Ile Met Asn Asn Lys
2065                2070                2075                2080
 Val Phe Tyr Gln His Pro Asn Leu Met Arg Val Leu Gly Met His Glu
                2085                2090                2095    
 Thr Val Met Glu Val Met Val Asn Val Leu Gly Thr Glu Lys Ser Gln
            2100                2105                2110        
 Ile Ala Phe Pro Lys Met Val Ala Ser Cys Cys Arg Phe Leu Cys Tyr
        2115                2120                2125            
 Phe Cys Arg Ile Ser Arg Gln Asn Gln Lys Ala Met Phe Glu His Leu
    2130                2135                2140                
 Ser Tyr Leu Leu Glu Asn Ser Ser Val Gly Leu Ala Ser Pro Ser Met
2145                2150                2155                2160
 Arg Gly Ser Thr Pro Leu Asp Val Ala Ala Ser Ser Val Met Asp Asn
                2165                2170                2175    
 Asn Glu Leu Ala Leu Ser Leu Glu Glu Pro Asp Leu Glu Lys Val Val
            2180                2185                2190        
 Thr Tyr Leu Ala Gly Cys Gly Leu Gln Ser Cys Pro Met Leu Leu Ala
        2195                2200                2205            
 Lys Gly Tyr Pro Asp Val Gly Trp Asn Pro Ile Glu Gly Glu Arg Tyr
    2210                2215                2220                
 Leu Ser Phe Leu Arg Phe Ala Val Phe Val Asn Ser Glu Ser Val Glu
2225                2230                2235                2240
 Glu Asn Ala Ser Val Val Val Lys Leu Leu Ile Arg Arg Pro Glu Cys
                2245                2250                2255    
 Phe Gly Pro Ala Leu Arg Gly Glu Gly Gly Asn Gly Leu Leu Ala Ala
            2260                2265                2270        
 Met Gln Gly Ala Ile Lys Ile Ser Glu Asn Pro Ala Leu Asp Leu Pro
        2275                2280                2285            
 Ser Gln Gly Tyr Lys Arg Glu Val Ser Thr Glu Asp Asp Glu Glu Glu
    2290                2295                2300                
 Glu Glu Ile Val His Met Gly Asn Ala Ile Met Ser Phe Tyr Ser Ala
2305                2310                2315                2320
 Leu Ile Asp Leu Leu Gly Arg Cys Ala Pro Glu Met His Leu Ile Gln
                2325                2330                2335    
 Thr Gly Lys Gly Glu Ala Ile Arg Ile Arg Ser Ile Leu Arg Ser Leu
            2340                2345                2350        
 Val Pro Thr Glu Asp Leu Val Gly Ile Ile Ser Ile Pro Leu Lys Leu
        2355                2360                2365            
 Pro Ser Leu Asn Lys Asp Gly Ser Val Ser Glu Pro Asp Met Ala Gly
    2370                2375                2380                
 Asn Phe Cys Pro Asp His Lys Ala Pro Met Val Leu Phe Leu Asp Arg
2385                2390                2395                2400
 Val Tyr Gly Ile Lys Asp Gln Thr Phe Leu Leu His Leu Leu Glu Val
                2405                2410                2415    
 Gly Phe Leu Pro Asp Leu Arg Ala Ser Ala Ser Leu Asp Thr Val Ser
            2420                2425                2430        
 Leu Ser Thr Thr Glu Ala Ala Leu Ala Leu Asn Arg Tyr Ile Cys Ser
        2435                2440                2445            
 Ala Val Leu Pro Leu Leu Thr Arg Cys Ala Pro Leu Phe Gly Gly Thr
    2450                2455                2460                
 Glu His Cys Thr Ser Leu Ile Asp Ser Thr Leu Gln Thr Ile Tyr Arg
2465                2470                2475                2480
 Leu Ser Lys Gly Arg Ser Leu Thr Lys Ala Gln Arg Asp Thr Ile Glu
                2485                2490                2495    
 Glu Cys Leu Leu Ala Ile Cys Asn His Leu Arg Pro Ser Met Leu Gln
            2500                2505                2510        
 Gln Leu Leu Arg Arg Leu Val Phe Asp Val Pro Gln Leu Asn Glu Tyr
        2515                2520                2525            
 Cys Lys Met Pro Leu Lys Leu Leu Thr Asn His Tyr Glu Gln Cys Trp
    2530                2535                2540                
 Lys Tyr Tyr Cys Leu Pro Ser Gly Trp Gly Ser Tyr Gly Leu Ala Val
2545                2550                2555                2560
 Glu Glu Glu Leu His Leu Thr Glu Lys Leu Phe Trp Gly Ile Ile Asp
                2565                2570                2575    
 Ser Leu Ser His Lys Lys Tyr Asp Pro Asp Leu Phe Arg Met Ala Leu
            2580                2585                2590        
 Pro Cys Leu Ser Ala Ile Ala Gly Ala Leu Pro Pro Asp Tyr Leu Asp
        2595                2600                2605            
 Ser Arg Ile Thr Ala Thr Leu Glu Lys Gln Ile Ser Val Asp Ala Asp
    2610                2615                2620                
 Gly Asn Phe Asp Pro Lys Pro Ile Asn Thr Met Asn Phe Ser Leu Pro
2625                2630                2635                2640
 Glu Lys Leu Glu Tyr Ile Val Thr Lys Tyr Ala Glu His Ser His Asp
                2645                2650                2655    
 Lys Trp Ala Cys Asp Lys Ser Gln Ser Gly Trp Lys Tyr Gly Ile Ser
            2660                2665                2670        
 Leu Asp Glu Asn Val Lys Thr His Pro Leu Ile Arg Pro Phe Lys Thr
        2675                2680                2685            
 Leu Thr Glu Lys Glu Lys Glu Ile Tyr Arg Trp Pro Ala Arg Glu Ser
    2690                2695                2700                
 Leu Lys Thr Met Leu Ala Val Gly Trp Thr Val Glu Arg Thr Lys Glu
2705                2710                2715                2720
 Gly Glu Ala Leu Val Gln Gln Arg Glu Asn Glu Lys Leu Arg Ser Val
                2725                2730                2735    
 Ser Gln Ala Asn Gln Gly Asn Ser Tyr Ser Pro Ala Pro Leu Asp Leu
            2740                2745                2750        
 Ser Asn Val Val Leu Ser Arg Glu Leu Gln Gly Met Val Glu Val Val
        2755                2760                2765            
 Ala Glu Asn Tyr His Asn Ile Trp Ala Lys Lys Lys Lys Leu Glu Leu
    2770                2775                2780                
 Glu Ser Lys Gly Gly Gly Ser His Pro Leu Leu Val Pro Tyr Asp Thr
2785                2790                2795                2800
 Leu Thr Ala Lys Glu Lys Phe Lys Asp Arg Glu Lys Ala Gln Asp Leu
                2805                2810                2815    
 Phe Lys Phe Leu Gln Val Asn Gly Ile Ile Val Ser Arg Gly Met Lys
            2820                2825                2830        
 Asp Met Glu Leu Asp Ala Ser Ser Met Glu Lys Arg Phe Gly Tyr Lys
        2835                2840                2845            
 Phe Leu Lys Lys Ile Leu Lys Tyr Val Asp Ser Ala Gln Glu Phe Ile
    2850                2855                2860                
 Ala His Leu Glu Ala Ile Val Ser Ser Gly Lys Thr Glu Lys Ser Pro
2865                2870                2875                2880
 Arg Asp Gln Glu Ile Lys Phe Phe Ala Lys Val Leu Leu Pro Leu Val
                2885                2890                2895    
 Asp Gln Tyr Phe Thr Ser His Cys Leu Tyr Phe Leu Ser Ser Pro Leu
            2900                2905                2910        
 Lys Pro Leu Ser Ser Ser Gly Tyr Ala Ser His Lys Glu Lys Glu Met
        2915                2920                2925            
 Val Ala Gly Leu Phe Cys Lys Leu Ala Ala Leu Val Arg His Arg Ile
    2930                2935                2940                
 Ser Leu Phe Gly Ser Asp Ser Thr Thr Met Val Ser Cys Leu His Ile
2945                2950                2955                2960
 Leu Ala Gln Thr Leu Asp Thr Arg Thr Val Met Lys Ser Gly Ser Glu
                2965                2970                2975    
 Leu Val Lys Ala Gly Leu Arg Ala Phe Phe Glu Asn Ala Ala Glu Asp
            2980                2985                2990        
 Leu Glu Lys Thr Ser Glu Asn Leu Lys Leu Gly Lys Phe Thr His Ser
        2995                3000                3005            
 Arg Thr Gln Ile Lys Gly Val Ser Gln Asn Ile Asn Tyr Thr Thr Val
    3010                3015                3020                
 Ala Leu Leu Pro Ile Leu Thr Ser Ile Phe Glu His Val Thr Gln His
3025                3030                3035                3040
 Gln Phe Gly Met Asp Leu Leu Leu Gly Asp Val Gln Ile Ser Cys Tyr
                3045                3050                3055    
 His Ile Leu Cys Ser Leu Tyr Ser Leu Gly Thr Gly Lys Asn Ile Tyr
            3060                3065                3070        
 Val Glu Arg Gln Arg Pro Ala Leu Gly Glu Cys Leu Ala Ser Leu Ala
        3075                3080                3085            
 Ala Ala Ile Pro Val Ala Phe Leu Glu Pro Thr Leu Asn Arg Tyr Asn
    3090                3095                3100                
 Pro Leu Ser Val Phe Asn Thr Lys Thr Pro Arg Glu Arg Ser Ile Leu
3105                3110                3115                3120
 Gly Met Pro Asp Thr Val Glu Asp Met Cys Pro Asp Ile Pro Gln Leu
                3125                3130                3135    
 Glu Gly Leu Met Lys Glu Ile Asn Asp Leu Ala Glu Ser Gly Ala Arg
            3140                3145                3150        
 Tyr Thr Glu Met Pro His Val Ile Glu Val Ile Leu Pro Met Leu Cys
        3155                3160                3165            
 Asn Tyr Leu Ser Tyr Trp Trp Glu Arg Gly Pro Glu Asn Leu Pro Pro
    3170                3175                3180                
 Ser Thr Gly Pro Cys Cys Thr Lys Val Thr Ser Glu His Leu Ser Leu
3185                3190                3195                3200
 Ile Leu Gly Asn Ile Leu Lys Ile Ile Asn Asn Asn Leu Gly Ile Asp
                3205                3210                3215    
 Glu Ala Ser Trp Met Lys Arg Ile Ala Val Tyr Ala Gln Pro Ile Ile
            3220                3225                3230        
 Ser Lys Ala Arg Pro Asp Leu Leu Arg Ser His Phe Ile Pro Thr Leu
        3235                3240                3245            
 Glu Lys Leu Lys Lys Lys Ala Val Lys Thr Val Gln Glu Glu Glu Gln
    3250                3255                3260                
 Leu Lys Ala Asp Gly Lys Gly Asp Thr Gln Glu Ala Glu Leu Leu Ile
3265                3270                3275                3280
 Leu Asp Glu Phe Ala Val Leu Cys Arg Asp Leu Tyr Ala Phe Tyr Pro
                3285                3290                3295    
 Met Leu Ile Arg Tyr Val Asp Asn Asn Arg Ser Asn Trp Leu Lys Ser
            3300                3305                3310        
 Pro Asp Ala Asp Ser Asp Gln Leu Phe Arg Met Val Ala Glu Val Phe
        3315                3320                3325            
 Ile Leu Trp Cys Lys Ser His Asn Phe Lys Arg Glu Glu Gln Asn Phe
    3330                3335                3340                
 Val Ile Gln Asn Glu Ile Asn Asn Leu Ala Phe Leu Thr Gly Asp Ser
3345                3350                3355                3360
 Lys Ser Lys Met Ser Lys Ala Met Gln Val Lys Ser Gly Gly Gln Asp
                3365                3370                3375    
 Gln Glu Arg Lys Lys Thr Lys Arg Arg Gly Asp Leu Tyr Ser Ile Gln
            3380                3385                3390        
 Thr Ser Leu Ile Val Ala Ala Leu Lys Lys Met Leu Pro Ile Gly Leu
        3395                3400                3405            
 Asn Met Cys Thr Pro Gly Asp Gln Glu Leu Ile Ser Leu Ala Lys Ser
    3410                3415                3420                
 Arg Tyr Ser His Arg Asp Thr Asp Glu Glu Val Arg Glu His Leu Arg
3425                3430                3435                3440
 Asn Asn Leu His Leu Gln Glu Lys Ser Asp Asp Pro Ala Val Lys Trp
                3445                3450                3455    
 Gln Leu Asn Leu Tyr Lys Asp Val Leu Lys Ser Glu Glu Pro Phe Asn
            3460                3465                3470        
 Pro Glu Lys Thr Val Glu Arg Val Gln Arg Ile Ser Ala Ala Val Phe
        3475                3480                3485            
 His Leu Glu Gln Val Glu Gln Pro Leu Arg Ser Lys Lys Ala Val Trp
    3490                3495                3500                
 His Lys Leu Leu Ser Lys Gln Arg Lys Arg Ala Val Val Ala Cys Phe
3505                3510                3515                3520
 Arg Met Ala Pro Leu Tyr Asn Leu Pro Arg His Arg Ser Ile Asn Leu
                3525                3530                3535    
 Phe Leu His Gly Tyr Gln Arg Phe Trp Ile Glu Thr Glu Glu Tyr Ser
            3540                3545                3550        
 Phe Glu Glu Lys Leu Val Gln Asp Leu Ala Lys Ser Pro Lys Val Glu
        3555                3560                3565            
 Glu Glu Glu Glu Glu Glu Thr Glu Lys Gln Pro Asp Pro Leu His Gln
    3570                3575                3580                
 Ile Ile Leu Tyr Phe Ser Arg Asn Ala Leu Thr Glu Arg Ser Lys Leu
3585                3590                3595                3600
 Glu Asp Asp Pro Leu Tyr Thr Ser Tyr Ser Ser Met Met Ala Lys Ser
                3605                3610                3615    
 Cys Gln Ser Gly Glu Asp Glu Glu Glu Asp Glu Asp Lys Glu Lys Thr
            3620                3625                3630        
 Phe Glu Glu Lys Glu Met Glu Lys Gln Lys Thr Leu Tyr Gln Gln Ala
        3635                3640                3645            
 Arg Leu His Glu Arg Gly Ala Ala Glu Met Val Leu Gln Met Ile Ser
    3650                3655                3660                
 Ala Ser Lys Gly Glu Met Ser Pro Met Val Val Glu Thr Leu Lys Leu
3665                3670                3675                3680
 Gly Ile Ala Ile Leu Asn Gly Gly Asn Ala Gly Val Gln Gln Lys Met
                3685                3690                3695    
 Leu Asp Tyr Leu Lys Glu Lys Lys Asp Ala Gly Phe Phe Gln Ser Leu
            3700                3705                3710        
 Ser Gly Leu Met Gln Ser Cys Ser Val Leu Asp Leu Asn Ala Phe Glu
        3715                3720                3725            
 Arg Gln Asn Lys Ala Glu Gly Leu Gly Met Val Thr Glu Glu Gly Thr
    3730                3735                3740                
 Leu Ile Val Arg Glu Arg Gly Glu Lys Val Leu Gln Asn Asp Glu Phe
3745                3750                3755                3760
 Thr Arg Asp Leu Phe Arg Phe Leu Gln Leu Leu Cys Glu Gly His Asn
                3765                3770                3775    
 Ser Asp Phe Gln Asn Phe Leu Arg Thr Gln Met Gly Asn Thr Thr Thr
            3780                3785                3790        
 Val Asn Val Ile Ile Ser Thr Val Asp Tyr Leu Leu Arg Leu Gln Glu
        3795                3800                3805            
 Ser Ile Ser Asp Phe Tyr Trp Tyr Tyr Ser Gly Lys Asp Ile Ile Asp
    3810                3815                3820                
 Glu Ser Gly Gln His Asn Phe Ser Lys Ala Leu Ala Val Thr Lys Gln
3825                3830                3835                3840
 Ile Phe Asn Ser Leu Thr Glu Tyr Ile Gln Gly Pro Cys Ile Gly Asn
                3845                3850                3855    
 Gln Gln Ser Leu Ala His Ser Arg Leu Trp Asp Ala Val Val Gly Phe
            3860                3865                3870        
 Leu His Val Phe Ala Asn Met Gln Met Lys Leu Ser Gln Asp Ser Ser
        3875                3880                3885            
 Gln Ile Glu Leu Leu Lys Glu Leu Leu Asp Leu Leu Gln Asp Met Val
    3890                3895                3900                
 Val Met Leu Leu Ser Leu Leu Glu Gly Asn Val Val Asn Gly Thr Ile
3905                3910                3915                3920
 Gly Lys Gln Met Val Asp Thr Leu Val Glu Ser Ser Thr Asn Val Glu
                3925                3930                3935    
 Met Ile Leu Lys Phe Phe Asp Met Phe Leu Lys Leu Lys Asp Leu Thr
            3940                3945                3950        
 Ser Ser Asp Thr Phe Lys Glu Tyr Asp Pro Asp Gly Lys Gly Ile Ile
        3955                3960                3965            
 Ser Lys Lys Glu Phe Gln Lys Ala Met Glu Gly Gln Lys Gln Tyr Thr
    3970                3975                3980                
 Gln Ser Glu Ile Asp Phe Leu Leu Ser Cys Ala Glu Ala Asp Glu Asn
3985                3990                3995                4000
 Asp Met Phe Asn Tyr Val Asp Phe Val Asp Arg Phe His Glu Pro Ala
                4005                4010                4015    
 Lys Asp Ile Gly Phe Asn Val Ala Val Leu Leu Thr Asn Leu Ser Glu
            4020                4025                4030        
 His Met Pro Asn Asp Ser Arg Leu Lys Cys Leu Leu Asp Pro Ala Glu
        4035                4040                4045            
 Ser Val Leu Asn Tyr Phe Glu Pro Tyr Leu Gly Arg Ile Glu Ile Met
    4050                4055                4060                
 Gly Gly Ala Lys Lys Ile Glu Arg Val Tyr Phe Glu Ile Ser Glu Ser
4065                4070                4075                4080
 Ser Arg Thr Gln Trp Glu Lys Pro Gln Val Lys Glu Ser Lys Arg Gln
                4085                4090                4095    
 Phe Ile Phe Asp Val Val Asn Glu Gly Gly Glu Gln Glu Lys Met Glu
            4100                4105                4110        
 Leu Phe Val Asn Phe Cys Glu Asp Thr Ile Phe Glu Met Gln Leu Ala
        4115                4120                4125            
 Ser Gln Ile Ser Glu Ser Asp Ser Ala Asp Arg Pro Glu Glu Glu Glu
    4130                4135                4140                
 Glu Asp Glu Asp Ser Ser Tyr Val Leu Glu Ile Ala Gly Glu Glu Glu
4145                4150                4155                4160
 Glu Asp Gly Ser Leu Glu Pro Ala Ser Ala Phe Ala Met Ala Cys Ala
                4165                4170                4175    
 Ser Val Lys Arg Asn Val Thr Asp Phe Leu Lys Arg Ala Thr Leu Lys
            4180                4185                4190        
 Asn Leu Arg Lys Gln Tyr Arg Asn Val Lys Lys Met Thr Ala Lys Glu
        4195                4200                4205            
 Leu Val Lys Val Leu Phe Ser Phe Phe Trp Met Leu Phe Val Gly Leu
    4210                4215                4220                
 Phe Gln Leu Leu Phe Thr Ile Leu Gly Gly Ile Phe Gln Ile Leu Trp
4225                4230                4235                4240
 Ser Thr Val Phe Gly Gly Gly Leu Val Glu Gly Ala Lys Asn Ile Arg
                4245                4250                4255    
 Val Thr Lys Ile Leu Gly Asp Met Pro Asp Pro Thr Gln Phe Gly Ile
            4260                4265                4270        
 His Asp Asp Thr Met Glu Ala Glu Arg Ala Glu Val Met Glu Pro Gly
        4275                4280                4285            
 Ile Thr Thr Glu Leu Val His Phe Ile Lys Gly Glu Lys Gly Asp Thr
    4290                4295                4300                
 Asp Ile Met Ser Asp Leu Phe Gly Leu His Pro Lys Lys Glu Gly Ser
4305                4310                4315                4320
 Leu Lys His Gly Pro Glu Val Gly Leu Gly Asp Leu Ser Glu Ile Ile
                4325                4330                4335    
 Gly Lys Asp Glu Pro Pro Thr Leu Glu Ser Thr Val Gln Lys Lys Arg
            4340                4345                4350        
 Lys Ala Gln Ala Ala Glu Met Lys Ala Ala Asn Glu Ala Glu Gly Lys
        4355                4360                4365            
 Val Glu Ser Glu Lys Ala Asp Met Glu Asp Gly Glu Lys Glu Asp Lys
    4370                4375                4380                
 Asp Lys Glu Glu Glu Gln Ala Glu Tyr Leu Trp Thr Glu Val Thr Lys
4385                4390                4395                4400
 Lys Lys Lys Arg Arg Cys Gly Gln Lys Val Glu Lys Pro Glu Ala Phe
                4405                4410                4415    
 Thr Ala Asn Phe Phe Lys Gly Leu Glu Ile Tyr Gln Thr Lys Leu Leu
            4420                4425                4430        
 His Tyr Leu Ala Arg Asn Phe Tyr Asn Leu Arg Phe Leu Ala Leu Phe
        4435                4440                4445            
 Val Ala Phe Ala Ile Asn Phe Ile Leu Leu Phe Tyr Lys Val Thr Glu
    4450                4455                4460                
 Glu Pro Leu Glu Glu Glu Thr Glu Asp Val Ala Asn Leu Trp Asn Ser
4465                4470                4475                4480
 Phe Asn Asp Glu Glu Glu Glu Glu Ala Met Val Phe Phe Val Leu Gln
                4485                4490                4495    
 Glu Ser Thr Gly Tyr Met Ala Pro Thr Leu Arg Ala Leu Ala Ile Ile
            4500                4505                4510        
 His Thr Ile Ile Ser Leu Val Cys Val Val Gly Tyr Tyr Cys Leu Lys
        4515                4520                4525            
 Val Pro Leu Val Val Phe Lys Arg Glu Lys Glu Ile Ala Arg Lys Leu
    4530                4535                4540                
 Glu Phe Asp Gly Leu Tyr Ile Thr Glu Gln Pro Ser Glu Asp Asp Ile
4545                4550                4555                4560
 Lys Gly Gln Trp Asp Arg Leu Val Ile Asn Thr Pro Ser Phe Pro Asn
                4565                4570                4575    
 Asn Tyr Trp Asp Lys Phe Val Lys Arg Lys Val Ile Asn Lys Tyr Gly
            4580                4585                4590        
 Asp Leu Tyr Gly Ala Glu Arg Ile Ala Glu Leu Leu Gly Leu Asp Lys
        4595                4600                4605            
 Asn Ala Leu Asp Phe Ser Pro Val Glu Glu Thr Lys Ala Glu Ala Ala
    4610                4615                4620                
 Ser Leu Val Ser Trp Leu Ser Ser Ile Asp Met Lys Tyr His Ile Trp
4625                4630                4635                4640
 Lys Leu Gly Val Val Phe Thr Asp Asn Ser Phe Leu Tyr Leu Ala Trp
                4645                4650                4655    
 Tyr Thr Thr Met Ser Val Leu Gly His Tyr Asn Asn Phe Phe Phe Ala
            4660                4665                4670        
 Ala His Leu Leu Asp Ile Ala Met Gly Phe Lys Thr Leu Arg Thr Ile
        4675                4680                4685            
 Leu Ser Ser Val Thr His Asn Gly Lys Gln Leu Val Leu Thr Val Gly
    4690                4695                4700                
 Leu Leu Ala Val Val Val Tyr Leu Tyr Thr Val Val Ala Phe Asn Phe
4705                4710                4715                4720
 Phe Arg Lys Phe Tyr Asn Lys Ser Glu Asp Asp Asp Glu Pro Asp Met
                4725                4730                4735    
 Lys Cys Asp Asp Met Met Thr Cys Tyr Leu Phe His Met Tyr Val Gly
            4740                4745                4750        
 Val Arg Ala Gly Gly Gly Ile Gly Asp Glu Ile Glu Asp Pro Ala Gly
        4755                4760                4765            
 Asp Pro Tyr Glu Met Tyr Arg Ile Val Phe Asp Ile Thr Phe Phe Phe
    4770                4775                4780                
 Phe Val Ile Val Ile Leu Leu Ala Ile Ile Gln Gly Leu Ile Ile Asp
4785                4790                4795                4800
 Ala Phe Gly Glu Leu Arg Asp Gln Gln Glu Gln Val Arg Glu Asp Met
                4805                4810                4815    
 Glu Thr Lys Cys Phe Ile Cys Gly Ile Gly Asn Asp Tyr Phe Asp Thr
            4820                4825                4830        
 Thr Pro His Gly Phe Glu Thr His Thr Leu Gln Glu His Asn Leu Ala
        4835                4840                4845            
 Asn Tyr Leu Phe Phe Leu Met Tyr Leu Ile Asn Lys Asp Glu Thr Glu
    4850                4855                4860                
 His Thr Gly Gln Glu Ser Tyr Val Trp Lys Met Tyr Gln Glu Arg Cys
4865                4870                4875                4880
 Trp Asp Phe Phe Pro Ala Gly Asp Cys Phe Arg Lys Gln Tyr Glu Asp
                4885                4890                4895    
 Gln Leu Gly
            



      <210> 2661
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 2661
 Met Leu Asn Ser Ser Glu Gln Arg Arg Pro His Gly Val Leu Asp Ser
   1               5                  10                  15    
 Val Trp Pro Gly Ile His Gly Ala Leu Cys Ala Gly Arg Trp Leu Arg
              20                  25                  30        
 Thr Gly Gln Leu Ser Trp Asp Thr Arg His Met Leu Ala Arg Lys Met
          35                  40                  45            
 Val Ser Ser Ser Glu Pro Gln Arg Pro Pro Thr Ser Trp Ser Trp Cys
      50                  55                  60                
 Cys Leu Ala Ser Thr Val Arg Pro Leu Leu Val Asp Gly Ser Gly Trp
  65                  70                  75                  80
 Gly Ser Cys Arg Gly Arg Pro Ala Ala Cys Trp Lys Glu Asp Gly Gln
                  85                  90                  95    
 Phe Phe
        



      <210> 2662
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 2662
 Ser Ser Ala Leu Leu Ser Ser Asn Gln Thr Ala Ser Phe Gly Ser Cys
   1               5                  10                  15    
 Ser Leu Ser Leu Pro Cys Ser Ala Arg Glu Arg Thr Pro Glu Gly Gly
              20                  25                  30        
 Gly Trp Pro Gly Gly Arg Leu Ser Glu Pro Leu Pro Ala Met Leu Leu
          35                  40                  45            
 Leu Trp Val Ser Val Val Ala Ala Leu Ala Leu Ala Val Leu Ala Pro
      50                  55                  60                
 Gly Ala Gly Glu Gln Arg Arg Arg Ala Ala Lys Ala Pro Asn Val Val
  65                  70                  75                  80
 Leu Val Val Ser Asp Ser Phe Asp Gly Arg Leu Thr Phe His Pro Gly
                  85                  90                  95    
 Ser Gln Val Val Lys Leu Pro Phe Ile Asn Phe Met Lys Thr Arg Gly
             100                 105                 110        
 Thr Ser Phe Leu Asn Ala Tyr Thr Asn Ser Pro Ile Cys Cys Pro Ser
         115                 120                 125            
 Arg Ala Ala Met Trp Ser Gly Leu Phe Thr His Leu Thr Glu Ser Trp
     130                 135                 140                
 Asn Asn Phe Lys Gly Leu Asp Pro Asn Tyr Thr Thr Trp Met Asp Val
 145                 150                 155                 160
 Met Glu Arg His Gly Tyr Arg Thr Gln Lys Phe Gly Lys Leu Asp Tyr
                 165                 170                 175    
 Thr Ser Gly His His Ser Ile Arg His Ser Glu Arg Gly Ser Thr Asn
             180                 185                 190        
 Gln Arg Ser Glu Lys Val
         195            



      <210> 2663
      <211> 61
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(61)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2663
 Met Pro Val Trp Trp Arg Arg Arg Arg Leu Arg Ala Arg Ser Trp Ala
   1               5                  10                  15    
 Leu Arg Ala Arg Pro Leu Ser Leu Pro Arg Ala Gln Arg Ser Gly Arg
              20                  25                  30        
 Leu Leu Arg Arg Pro Lys Gly Tyr Ala Pro Gly Ala Pro Lys Ala His
          35                  40                  45            
 Glu Leu Ser Pro Gln Ala Ile Cys Ala Val Ala Phe Xaa
      50                  55                  60    



      <210> 2664
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 2664
 Met Val Ile Leu Asn Ala Leu Gln Arg Arg Ala Phe Leu Cys Ala Ala
   1               5                  10                  15    
 Asn Val Lys Ile Pro Arg Leu Arg Ile Lys Val Lys Thr Lys Glu Ala
              20                  25                  30        
 Ser Ala Gln Val Val Lys Glu Glu Cys Asn Lys Tyr Leu Leu Phe Leu
          35                  40                  45            
 Leu Pro Val Pro Ser Ala Gly Leu Leu Pro Ser Ile Met Glu Ile Ala
      50                  55                  60                
 Asp Pro Phe Ser Ser Phe Gly Ser Glu Asp Lys Cys Tyr Thr Leu Thr
  65                  70                  75                  80
 Pro Pro Leu Pro Arg His Thr Glu Lys Ser Ser Asp Ser Gln Glu Lys
                  85                  90                  95    
 Gly His Phe Glu Ala Gly Val Glu Pro Lys Ser Arg Gly Ser Thr Pro
             100                 105                 110        
 Gly Gln Tyr Pro Gly Ile Gly Cys Phe Ala Arg Phe Arg Glu Tyr Gln
         115                 120                 125            
 Ile Gly Met Arg His Leu Thr Thr Arg Pro Ala Met His Arg Ala Gln
     130                 135                 140                
 Val Leu Phe Pro Leu Ser Phe
 145                 150    



      <210> 2665
      <211> 193
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(193)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2665
 Phe Leu Thr Arg Glu Thr Gly Asp Pro Thr Gly Arg Ser Ser Ser His
   1               5                  10                  15    
 Ala Asn Thr Gln Ser Arg Phe Phe Pro Asp Asp Pro Pro Gly Pro Leu
              20                  25                  30        
 Asn Asn Leu Gly Asn Thr His Gly Cys Gly Arg Arg Ala Gly Arg Cys
          35                  40                  45            
 Pro Gly Thr Gly Pro Asp Gly Pro Ala Gly Cys Gly Gly Pro Arg Cys
      50                  55                  60                
 Trp Pro Ser Gly His Leu Ala Ala Thr Gly Asp Xaa Gly Pro Ser Cys
  65                  70                  75                  80
 Gly Arg Leu Gly Ala Asn Arg Gly Glu Ala Gly Pro Ala Gly Phe Thr
                  85                  90                  95    
 Ala Cys Ser Pro Leu Ser Gly Cys Arg Thr Pro Tyr Thr His His Phe
             100                 105                 110        
 Pro Ala Ser Arg Met Ser Cys His Leu Asn Cys Ala Ser Pro Arg Thr
         115                 120                 125            
 Tyr Arg Ser Gln Gly Asn Arg Gly Cys Glu Arg Val Ala Gln Gly Ser
     130                 135                 140                
 Gln Gly Ala Gly Gly Glu Arg Gly Ala Lys Ser Gln Val Pro Val Pro
 145                 150                 155                 160
 Ala Pro Ala Arg Asn Lys Asp Pro Ala Lys Cys Arg Lys Pro Arg Asn
                 165                 170                 175    
 Arg Arg Pro Gly Asn Ser Gly Pro Val Val Arg Ala Tyr Arg Arg Gln
             180                 185                 190        
 Arg
    



      <210> 2666
      <211> 616
      <212> PRT
      <213> Homo sapiens


      <400> 2666
 Arg Ala Arg Arg Leu Ala Leu Gln Cys His Val Cys Val Cys Ala Leu
   1               5                  10                  15    
 Thr Pro Gly Glu Gln Ser Gly Arg Arg Leu Pro Gly Gln Thr Trp Leu
              20                  25                  30        
 Met Phe Ser Cys Phe Cys Phe Ser Leu Gln Asp Asn Ser Phe Ser Ser
          35                  40                  45            
 Thr Thr Val Thr Glu Cys Asp Glu Asp Pro Val Ser Leu His Glu Asp
      50                  55                  60                
 Gln Thr Asp Cys Ser Ser Leu Arg Asp Glu Asn Asn Lys Glu Asn Tyr
  65                  70                  75                  80
 Pro Asp Ala Gly Ala Leu Val Glu Glu His Ala Pro Pro Ser Trp Glu
                  85                  90                  95    
 Pro Gln Gln Gln Asn Val Glu Ala Thr Val Leu Val Asp Ser Val Leu
             100                 105                 110        
 Arg Pro Ser Met Gly Asn Phe Lys Ser Arg Lys Pro Lys Ser Ile Phe
         115                 120                 125            
 Lys Ala Glu Ser Gly Arg Ser His Gly Glu Ser Gln Glu Thr Glu His
     130                 135                 140                
 Val Val Ser Ser Gln Ser Glu Cys Gln Val Arg Ala Gly Thr Pro Ala
 145                 150                 155                 160
 His Glu Ser Pro Gln Asn Asn Ala Phe Lys Cys Gln Glu Thr Val Arg
                 165                 170                 175    
 Leu Gln Pro Arg Ile Asp Gln Arg Thr Ala Thr Ser Pro Lys Asp Ala
             180                 185                 190        
 Phe Glu Thr Arg Gln Asp Leu Asn Glu Glu Glu Ala Ala Gln Val His
         195                 200                 205            
 Gly Val Lys Asp Pro Ala Pro Ala Ser Thr Gln Ser Val Leu Ala Asp
     210                 215                 220                
 Gly Thr Asp Ser Ala Asp Pro Ser Pro Val His Lys Asp Gly Gln Asn
 225                 230                 235                 240
 Glu Ala Asp Ser Ala Pro Glu Asp Leu His Ser Val Gly Thr Ser Arg
                 245                 250                 255    
 Leu Leu Leu Tyr His Ile Thr Asp Gly Asp Asn Pro Thr Ala Val Arg
             260                 265                 270        
 His Gly Cys Ser Leu Phe Ser Gly Gln Ser Gln Arg Phe Asn Leu Asp
         275                 280                 285            
 Pro Glu Ser Ala Pro Ser Pro Pro Ser Thr Gln Gln Phe Met Met Pro
     290                 295                 300                
 Arg Ser Ser Ser Arg Cys Ser Cys Gly Asp Gly Lys Glu Pro Gln Thr
 305                 310                 315                 320
 Ile Thr Gln Leu Thr Lys His Ile Gln Ser Leu Lys Arg Lys Ile Arg
                 325                 330                 335    
 Lys Phe Glu Glu Lys Phe Glu Gln Glu Lys Lys Tyr Arg Pro Ser His
             340                 345                 350        
 Gly Asp Lys Thr Ser Asn Pro Glu Val Leu Lys Trp Met Asn Asp Leu
         355                 360                 365            
 Ala Lys Gly Arg Lys Gln Leu Lys Glu Leu Lys Leu Lys Leu Ser Glu
     370                 375                 380                
 Glu Gln Gly Ser Ala Pro Lys Gly Pro Pro Arg Asn Leu Leu Cys Glu
 385                 390                 395                 400
 Gln Pro Thr Val Pro Arg Glu Ser Gly Lys Pro Glu Ala Ala Gly Pro
                 405                 410                 415    
 Glu Pro Ser Ser Ser Gly Glu Glu Thr Pro Asp Ala Ala Leu Thr Cys
             420                 425                 430        
 Leu Lys Glu Arg Arg Glu Gln Leu Pro Pro Gln Glu Asp Ser Lys Val
         435                 440                 445            
 Thr Lys Gln Asp Lys Asn Leu Ile Lys Pro Leu Tyr Asp Arg Tyr Arg
     450                 455                 460                
 Ile Ile Lys Gln Ile Leu Ser Thr Pro Ser Leu Ile Pro Thr Ile Gln
 465                 470                 475                 480
 Glu Glu Glu Asp Ser Asp Glu Asp Arg Pro Gln Gly Ser Gln Gln Pro
                 485                 490                 495    
 Ser Leu Ala Asp Pro Ala Ser His Leu Pro Val Gly Asp His Leu Thr
             500                 505                 510        
 Tyr Ser Asn Glu Thr Glu Pro Val Arg Ala Leu Leu Pro Asp Glu Lys
         515                 520                 525            
 Lys Glu Val Lys Pro Pro Ala Leu Ser Met Ser Asn Leu His Glu Ala
     530                 535                 540                
 Thr Met Pro Val Leu Leu Asp His Leu Arg Glu Thr Arg Ala Asp Lys
 545                 550                 555                 560
 Lys Arg Leu Arg Lys Ala Leu Arg Glu Phe Glu Glu Gln Phe Phe Lys
                 565                 570                 575    
 Gln Thr Gly Arg Ser Pro Gln Lys Glu Asp Arg Ile Pro Met Ala Asp
             580                 585                 590        
 Glu Tyr Tyr Glu Tyr Lys His Ile Lys Ala Lys Leu Arg Leu Leu Ala
         595                 600                 605            
 Pro Pro Ala Gly Ser Tyr Phe Pro
     610                 615    



      <210> 2667
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 2667
 Met Tyr Lys Ala Gln Phe Leu Ala Ala Ser Pro Gly Arg Cys Leu Gly
   1               5                  10                  15    
 Leu Leu Ala Ala Ser Asn His His Ala Lys Ser Ile His Gly Phe Arg
              20                  25                  30        
 Arg Leu Val Lys Thr Met Arg Asn Arg Leu Cys Ser Leu Cys Gln Pro
          35                  40                  45            
 Phe Pro Leu Pro Lys His Leu Leu Ser Leu Ser Trp Phe Gly Asp Gln
      50                  55                  60                
 Gly His Thr Ser Gln Tyr Phe Thr Leu Ser Thr Gln Arg Asn Glu Ala
  65                  70                  75                  80
 Gln Leu Gln
            



      <210> 2668
      <211> 596
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(596)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2668
 Met Ser Lys Gly Glu Ser Arg Lys Cys Asn Glu Glu Asn Val Ser Lys
   1               5                  10                  15    
 Ser Ser Lys Val Val Lys Val Phe Ile Val Leu Thr Pro Gln Phe Leu
              20                  25                  30        
 Ser Arg Asp Lys Asp Gln Leu Thr Lys Glu Leu Gln Lys His Val Lys
          35                  40                  45            
 Ser Val Thr Val Ser Cys Lys Ser Pro Arg Lys Leu Leu Ser His Ile
      50                  55                  60                
 Thr Arg Leu His Pro Pro Ser Lys Gly Gln Gly Glu Asn Leu Thr His
  65                  70                  75                  80
 Leu Val Asp Ser Ile Lys Ala Thr Ile Trp Cys Gln Pro Val Trp Glu
                  85                  90                  95    
 Thr Val Glu Gly Gln Arg Arg Arg Val Gly Asn Cys Ile Asp Phe Thr
             100                 105                 110        
 Asn Gly Cys Asp Leu Val Gly Ser Ser Ser Leu His Asn Met Leu Val
         115                 120                 125            
 Cys Ser Ser Tyr Asp Ile Asn Arg Gln Asp Thr Phe Gln Lys Asp Arg
     130                 135                 140                
 Thr Ser Glu Lys His Leu Leu Asp Ser Val Phe Thr Ala Leu Gln Asp
 145                 150                 155                 160
 Ser Ala Gly Gln Gln Trp Pro Ala Arg Leu His Pro Gln Arg Gly Glu
                 165                 170                 175    
 Glu Val Ala Asp Pro Arg Gly Ala Pro Ser Arg His Val Glu Pro Glu
             180                 185                 190        
 Asn Ser Ser Pro Cys Gln Gly Asn Gly Glu Gln Ala Gly Lys Ala Gly
         195                 200                 205            
 Ala Arg Ala Leu Cys Gly Gln Ala Arg Arg Ser Pro Ala Thr Met Pro
     210                 215                 220                
 Pro Pro Leu Thr Thr Arg Ser Leu Cys Glu Phe Ala Val Phe Leu Leu
 225                 230                 235                 240
 His Trp Leu Phe Pro Glu Leu Phe His Tyr Arg Lys Leu Gly Glu Gln
                 245                 250                 255    
 Asp Ser Cys Tyr Gly Asp Gly Gly Lys Gln Glu Leu Asp Pro Gln Arg
             260                 265                 270        
 Leu Gln Ile Ile Cys Asn Phe Thr Glu Val Tyr Phe Pro His Met Gln
         275                 280                 285            
 Glu Glu Glu Ala Trp Arg Gln Ala Gly Pro Gly Pro Ala Glu Ala Ala
     290                 295                 300                
 Asp Thr Ser Ala Thr Ser Arg Arg Ser Thr Ser Pro Thr Cys Arg Arg
 305                 310                 315                 320
 Arg Arg Pro Gly Cys Ser Gly Ala Pro Ser Ala Ser Thr Thr Ser Phe
                 325                 330                 335    
 Arg Ala Trp Gly Trp Thr Gln Ala Ala Lys Ala Ser Pro Pro Arg Asp
             340                 345                 350        
 Asn Cys Tyr Asn Ser Ser Ser Leu Pro Asp Asp Ile Ser Leu Phe Thr
         355                 360                 365            
 His Asp Asn Leu His Lys Gln His Ser Cys Ser Asp Ser Leu Gly Lys
     370                 375                 380                
 Lys Gln Leu Asp Pro Ser Cys Ile Lys Leu Ile Arg His Xaa Val His
 385                 390                 395                 400
 Leu Leu Tyr Leu Cys Thr Lys Asn Asn Arg Val Trp Thr Leu Glu Phe
                 405                 410                 415    
 Met Gly Asn Leu His Trp Asn Arg Asn Arg Gly Ala Pro Thr Ser Ser
             420                 425                 430        
 Ser Ala Arg Ser Thr Cys Trp Pro Arg Val Xaa Arg His Glu Glu Leu
         435                 440                 445            
 Cys Asn Gln Ser Xaa Glu Val Gln Arg Gly Val Xaa Gly Ser Pro Ala
     450                 455                 460                
 Ala Pro Glu Arg Ser Ser Lys Asp Phe Cys Lys Ile Pro Leu Asp Glu
 465                 470                 475                 480
 Val Val Val Pro His Xaa Asp Phe Pro Val Arg Ser Pro Tyr Leu Leu
                 485                 490                 495    
 Ser Asp Lys Glu Val Cys Lys Ile Val Gln Gln Ser Leu Ser Val Gly
             500                 505                 510        
 Asn Phe Ala Ala Gly Leu Leu Leu Pro Pro Arg Thr Ser Ser Cys Ser
         515                 520                 525            
 Thr Thr Ile Phe Gly Leu Asp Asn Lys Lys Gln Leu Asp Pro Thr Gln
     530                 535                 540                
 Leu Arg Leu Ile Cys His Xaa Val Glu Ala Val Tyr Pro Val Glu Lys
 545                 550                 555                 560
 Val Glu Glu Val Trp His Cys Glu Cys Ile Pro Ser Asn Asp Glu Gln
                 565                 570                 575    
 Cys His Cys Pro Asn Arg Lys Lys Cys Asn Ile Leu Lys Lys Ala Lys
             580                 585                 590        
 Lys Val Glu Lys
         595    



      <210> 2669
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 2669
 Arg Arg Phe Arg Glu Pro Asp Ala Gln Met Leu Glu Ile Pro Asn Leu
   1               5                  10                  15    
 Thr Pro Tyr Thr His Tyr Arg Phe Arg Met Lys Gln Val Asn Ile Val
              20                  25                  30        
 Gly Pro Ser Pro Tyr Ser Pro Ser Ser Arg Val Ile Gln Thr Leu Gln
          35                  40                  45            
 Ala Pro Pro Asp Val Ala Pro Thr Ser Val Thr Val Arg Thr Ala Ser
      50                  55                  60                
 Glu Thr Ser Leu Arg Leu Arg Trp Val Pro Leu Pro Asp Ser Gln Tyr
  65                  70                  75                  80
 Asn Gly Asn Pro Glu Ser Val Gly Tyr Arg Ile Lys Tyr Trp Arg Ser
                  85                  90                  95    
 Asp Leu Gln Ser Ser Ala Val Ala Gln Val Val Ser Asp Arg Leu Glu
             100                 105                 110        
 Arg Glu Phe Thr Ile Glu Glu Leu Glu Glu Trp Met Glu Tyr Glu Leu
         115                 120                 125            
 Gln Met Gln Ala Phe Asn Ala Val Gly
     130                 135        



      <210> 2670
      <211> 274
      <212> PRT
      <213> Homo sapiens


      <400> 2670
 Met Arg Ala Leu Lys Leu Gln Arg Arg Lys Ser Phe Trp Ile Val Val
   1               5                  10                  15    
 Ala Trp Glu Ala Phe Val Gln Leu Val Asn Tyr Glu Cys Lys Val Gly
              20                  25                  30        
 Glu Trp Lys Gly Leu Ala His Cys Val Ser Gln Asn Asn Lys Tyr Arg
          35                  40                  45            
 Thr Thr Tyr Ile Ile Ala Gly Val Pro Asn Pro Gln Glu Pro Gly Tyr
      50                  55                  60                
 Thr Ala Gly Gly Gln Leu Lys Gly Asn Asp Leu Thr Val Leu His Leu
  65                  70                  75                  80
 Leu Val Ile Glu Gly Lys Trp Glu Ala Val Arg Lys Phe Pro Phe Lys
                  85                  90                  95    
 Lys Tyr Ile Val Asn Thr Ala Ile Val Lys Glu Ala Arg Lys Tyr Trp
             100                 105                 110        
 Val Glu Glu Gly Ser Ser Leu Ala Lys Ala Thr Arg Ser Asn Pro Gly
         115                 120                 125            
 Tyr Leu Gln Pro Tyr Met Arg Thr Gly Ile Pro Val Phe Ala Pro Pro
     130                 135                 140                
 Lys Leu Pro Phe Gly Pro Pro Cys Pro Leu Ser Cys Thr His Ile Asn
 145                 150                 155                 160
 Pro Lys Pro Gln Ala Pro Glu Ala Asp Gln Gln Leu Pro Ile His Leu
                 165                 170                 175    
 Ala Glu Ser His Phe His His Ser Ile Lys Pro Arg Ile His Pro Ser
             180                 185                 190        
 Ser Pro Cys Val Thr Arg Phe Phe Leu Asp Ala Glu Arg Glu Leu Gly
         195                 200                 205            
 Ile Gln Lys Ala Val Pro Trp Ser Phe Thr Leu Val Lys Lys Gln Lys
     210                 215                 220                
 Ser Leu Gly Leu Pro Ser Val Gln Asp Phe Gly Ser Val Tyr Lys Met
 225                 230                 235                 240
 Asn Ile Trp Ser Asp Val Ala Cys Cys Asp Pro Gln Leu Gln Gln Pro
                 245                 250                 255    
 Ala Ala Ser Ala Gln Thr Ser Ala Ile Ser Gln Leu Ser Arg Val Thr
             260                 265                 270        
 Glu Ser
        



      <210> 2671
      <211> 124
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(124)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2671
 Xaa Arg Thr Glu Arg Val His Leu Arg Ile Thr Pro Gly Asp Asp Ser
   1               5                  10                  15    
 Arg Lys Arg Ser Ser Ala Ser His Tyr Arg Val Ala Gly Ile Ser Arg
              20                  25                  30        
 Leu Thr Leu Ser Leu Asp Arg Glu Gln Leu Tyr Leu Glu Gln Ser Thr
          35                  40                  45            
 Glu Gly Pro Glu Gln Asp Lys Arg Glu Gly Lys Ser Ala Arg Ser Ser
      50                  55                  60                
 Ser Arg Glu Pro Thr Gly Gln Pro Arg Thr Leu Leu Gly Gly Met Arg
  65                  70                  75                  80
 Ala Arg Lys Arg Lys Thr Leu Val Leu Gly Pro Phe Pro Arg Val Ile
                  85                  90                  95    
 Ser Gly Ser Asn Ala Lys Met Asp Thr Leu Ser Pro Ala Cys Ala Cys
             100                 105                 110        
 Ala Phe Ala Leu Tyr Gly Ile Pro Lys Pro Ala Ala
         115                 120                



      <210> 2672
      <211> 254
      <212> PRT
      <213> Homo sapiens


      <400> 2672
 Leu Gly Thr Val Ser Tyr Gly Ala Asp Thr Met Asp Glu Ile Gln Ser
   1               5                  10                  15    
 His Val Arg Asp Ser Tyr Ser Gln Met Gln Ser Gln Ala Gly Gly Asn
              20                  25                  30        
 Asn Thr Gly Ser Thr Pro Leu Arg Lys Ala Gln Ser Ser Ala Pro Lys
          35                  40                  45            
 Val Arg Lys Ser Val Ser Ser Arg Ile His Glu Ala Val Lys Ala Ile
      50                  55                  60                
 Val Leu Cys His Asn Val Thr Pro Val Tyr Glu Ser Arg Ala Gly Val
  65                  70                  75                  80
 Thr Glu Glu Thr Glu Phe Ala Glu Ala Asp Gln Asp Phe Ser Asp Glu
                  85                  90                  95    
 Asn Arg Thr Tyr Gln Ala Ser Ser Pro Asp Glu Val Ala Leu Val Gln
             100                 105                 110        
 Trp Thr Glu Ser Val Gly Leu Thr Leu Val Ser Arg Asp Leu Thr Ser
         115                 120                 125            
 Met Gln Leu Lys Thr Pro Ser Gly Gln Val Leu Ser Phe Cys Ile Leu
     130                 135                 140                
 Gln Leu Phe Pro Phe Thr Ser Glu Ser Lys Arg Met Gly Val Ile Val
 145                 150                 155                 160
 Arg Asp Glu Ser Thr Ala Glu Ile Thr Phe Tyr Met Lys Gly Ala Asp
                 165                 170                 175    
 Val Ala Met Ser Pro Ile Val Gln Tyr Asn Asp Trp Leu Glu Glu Glu
             180                 185                 190        
 Cys Gly Asn Met Ala Arg Glu Gly Leu Arg Thr Leu Val Val Ala Lys
         195                 200                 205            
 Lys Ala Leu Thr Glu Glu Gln Tyr Gln Asp Phe Glu Val Ser Arg Leu
     210                 215                 220                
 Pro Gly Ile Pro Ser Ser Tyr Asp Arg Cys Leu Pro Tyr Ala Glu Ile
 225                 230                 235                 240
 Ser Ser Ser Cys Leu Cys Met Lys Leu Glu Leu Gly Ser Leu
                 245                 250                



      <210> 2673
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 2673
 Glu Pro Lys Ser Leu Ile Gln Ile Ile Lys Gln Ser Ile Val Glu Leu
   1               5                  10                  15    
 Lys Leu Gln Ala Glu Asp Ser Phe Val Leu Lys Val Val Gln Leu Glu
              20                  25                  30        
 Glu Leu Leu Gln Val Arg His Ser Val Phe Ile Val Gly Asn Ala Gly
          35                  40                  45            
 Ser Gly Lys Ser Gln Val Leu Thr Leu Ala Ser Asn Glu Arg Ile Pro
      50                  55                  60                
 Leu Asn Arg Thr Met Arg Leu Val Phe Glu Ile Ser His Leu Arg Thr
  65                  70                  75                  80
 Ala Thr Pro Ala Thr Val Ser Arg Ala Gly Ile Leu Tyr Ile Asn Pro
                  85                  90                  95    
 Ala Asp Leu Gly Trp Asn Pro Val Val Ser Ser Trp Ile Glu Arg Arg
             100                 105                 110        
 Lys Val Gln Ser Glu Lys Ala Asn Leu Met Ile Leu Phe Asp Lys Tyr
         115                 120                 125            
 Leu Pro Thr Cys Leu Asp Lys
     130                 135



      <210> 2674
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 2674
 Ser Trp Gly Val Trp Tyr Lys Tyr Gln Pro Leu Asp Leu Val Arg Arg
   1               5                  10                  15    
 Tyr Phe Gly Glu Lys Ile Gly Leu Tyr Phe Ala Trp Leu Gly Trp Tyr
              20                  25                  30        
 Thr Gly Met Leu Phe Pro Ala Ala Phe Ile Gly Leu Phe Val Phe Leu
          35                  40                  45            
 Tyr Gly Val Thr Thr Val Asp His Ser Gln Val Ser Lys Glu Val Cys
      50                  55                  60                
 Gln Ala Thr Asp Ile Ile Met Cys Pro Val Cys Asp Lys Tyr Cys Pro
  65                  70                  75                  80
 Phe Met Arg Leu Ser Asp Ser Cys Val Tyr Ala Lys Val Thr His Leu
                  85                  90                  95    
 Phe Asp Asn Gly Ala Thr Val Phe Ser Ala Val Phe Met Ala Val Trp
             100                 105                 110        
 Ala Thr Val Leu Met Glu Phe Gly Lys
         115                 120    



      <210> 2675
      <211> 611
      <212> PRT
      <213> Homo sapiens


      <400> 2675
 Met Val Asp Ser Leu Ile Ala Arg Val Gly Val Met Ala Arg Gly Asn
   1               5                  10                  15    
 Ala Ile Thr Leu Pro Val Cys Gly Arg Asp Val Lys Phe Thr Leu Glu
              20                  25                  30        
 Val Leu Arg Gly Asp Ser Val Glu Lys Thr Ser Arg Val Trp Ser Gly
          35                  40                  45            
 Asn Glu Arg Asp Gln Glu Leu Leu Thr Glu Asp Ala Leu Asp Asp Leu
      50                  55                  60                
 Ile Pro Ser Phe Leu Leu Thr Gly Gln Gln Thr Pro Ala Phe Gly Arg
  65                  70                  75                  80
 Arg Val Ser Gly Val Ile Glu Ile Ala Asp Gly Ser Arg Arg Arg Lys
                  85                  90                  95    
 Ala Ala Ala Leu Thr Glu Ser Asp Tyr Arg Val Leu Val Gly Glu Leu
             100                 105                 110        
 Asp Asp Glu Gln Met Ala Ala Leu Ser Arg Leu Gly Asn Asp Tyr Arg
         115                 120                 125            
 Pro Thr Ser Ala Tyr Glu Arg Gly Gln Arg Tyr Ala Ser Arg Leu Gln
     130                 135                 140                
 Asn Glu Phe Ala Gly Asn Ile Ser Ala Leu Ala Asp Ala Glu Asn Ile
 145                 150                 155                 160
 Ser His Ser Asp Lys Phe Asp Ala Asn Asp Pro Ile Leu Lys Asp Gln
                 165                 170                 175    
 Thr Gln Glu Trp Ser Gly Ser Ala Thr Phe Thr Ser Asp Gly Lys Ile
             180                 185                 190        
 Arg Leu Phe Tyr Thr Asp Tyr Ser Gly Lys His Tyr Gly Lys Gln Ser
         195                 200                 205            
 Leu Thr Thr Ala Gln Val Asn Val Ser Lys Ser Asp Asp Thr Leu Lys
     210                 215                 220                
 Ile Asn Gly Val Glu Asp His Lys Thr Ile Phe Asp Gly Asp Gly Lys
 225                 230                 235                 240
 Thr Tyr Gln Asn Val Gln Gln Phe Ile Asp Glu Gly Asn Tyr Thr Ser
                 245                 250                 255    
 Gly Asp Asn His Thr Leu Arg Asp Pro His Tyr Val Glu Asp Lys Gly
             260                 265                 270        
 His Lys Tyr Leu Val Phe Glu Ala Asn Thr Gly Thr Glu Asn Gly Tyr
         275                 280                 285            
 Gln Gly Glu Glu Ser Leu Phe Asn Lys Ala Tyr Tyr Gly Gly Gly Thr
     290                 295                 300                
 Asn Phe Phe Arg Lys Glu Ser Gln Lys Leu Gln Gln Ser Ala Lys Lys
 305                 310                 315                 320
 Arg Asp Ala Glu Leu Ala Asn Gly Ala Leu Val Asn Thr Gln Ser Thr
                 325                 330                 335    
 Thr Thr Arg Arg Pro Gly Ser Asn Ser Leu Ser His Leu Met Trp Pro
             340                 345                 350        
 Val Asp His Gln Lys Phe Gln Ser Val Thr Glu Met Cys Gly Ser Ile
         355                 360                 365            
 Leu Ser Arg Asp Phe Ala Asp Phe Gly Thr Thr Ile Lys Gln Asp Phe
     370                 375                 380                
 Arg Leu Leu Gly Gln Thr Ser Val Asp Arg Leu Leu Gln Leu Ser Gln
 385                 390                 395                 400
 Gly Gln Ala Val Lys Gly Asn Gln Leu Leu Pro Val Ser Leu Val Lys
                 405                 410                 415    
 Arg Lys Thr Thr Leu Ala Pro Asn Thr Gln Thr Ala Ser Pro Arg Ala
             420                 425                 430        
 Leu Ala Asp Ser Leu Met Gln Leu Ala Arg Gln Val Ser Arg Leu Glu
         435                 440                 445            
 Ser Gly Gln Asp Phe Ala Asp Phe Gly Thr Thr Ile Lys Gln Asp Phe
     450                 455                 460                
 Arg Leu Leu Gly Gln Thr Ser Val Asp Arg Leu Leu Gln Leu Ser Gln
 465                 470                 475                 480
 Gly Gln Ala Val Lys Gly Asn Gln Leu Leu Pro Val Ser Leu Val Lys
                 485                 490                 495    
 Arg Lys Thr Thr Leu Ala Pro Asn Thr Gln Thr Ala Ser Pro Arg Ala
             500                 505                 510        
 Leu Ala Asp Ser Leu Met Gln Leu Ala Arg Gln Val Ser Arg Leu Glu
         515                 520                 525            
 Ser Gly Gln Asp Phe Ala Asp Phe Gly Thr Thr Ile Lys Gln Asp Phe
     530                 535                 540                
 Arg Leu Leu Gly Gln Thr Ser Val Asp Arg Leu Leu Gln Leu Ser Gln
 545                 550                 555                 560
 Gly Gln Ala Val Lys Gly Asn Gln Leu Leu Pro Val Ser Leu Val Lys
                 565                 570                 575    
 Arg Lys Thr Thr Leu Ala Pro Asn Thr Gln Thr Ala Ser Pro Arg Ala
             580                 585                 590        
 Leu Ala Asp Ser Leu Met Gln Leu Ala Arg Gln Val Ser Arg Leu Glu
         595                 600                 605            
 Ser Gly Gln
     610    



      <210> 2676
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 2676
 Met Gly Lys Ala Met Leu Gln Leu Leu Ile Arg Ala His Trp Thr Val
   1               5                  10                  15    
 Phe Pro Cys Glu His Glu Asp Asn Ala Ala Ser Val Ser Val Thr Leu
              20                  25                  30        
 Cys Ser Asp Leu Ala Gly Gly Glu Val Val Ser Ala Val Leu Thr Gly
          35                  40                  45            
 Gln Ser Val Val Gln Thr Glu Lys Glu Ile Asp Arg Ser Ser Lys Pro
      50                  55                  60                
 Pro Ala Cys Leu Val Ala Pro Gln Val Val Phe Cys Ser Glu Val Leu
  65                  70                  75                  80
 Arg Val Asp Glu Ser Tyr His Arg Lys Tyr Pro Val Gln Leu Arg Pro
                  85                  90                  95    
 Val His Ile Ala Ala Lys
             100        



      <210> 2677
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 2677
 Arg Gly Lys Lys Ser Val Thr Thr Val Ala Gly Pro Met Ala Gln Asp
   1               5                  10                  15    
 Val Glu Ser Leu Ala Leu Cys Leu Gln Ala Leu Leu Ser Glu Asp Met
              20                  25                  30        
 Tyr Arg Leu Asp Pro Thr Val Leu Gln Met Pro Phe Arg Glu Glu Val
          35                  40                  45            
 Lys Thr Pro Phe Pro Thr Pro Gly Cys Ser Glu
      50                  55                



      <210> 2678
      <211> 119
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(119)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2678
 Met Lys Arg Arg Arg Gln Leu Arg Ala Arg Val Phe Ala Leu Ala Leu
   1               5                  10                  15    
 Ala Trp Ser Leu Gly Pro Cys Trp Ala Leu Arg Val Ala Val Pro Lys
              20                  25                  30        
 Ala Ser Xaa Thr Ile Arg Gly Pro Gln Arg Arg Leu Leu Ala Ser Leu
          35                  40                  45            
 Leu Gln Glu Asn Thr Glu Ile Leu Gly Tyr Leu Leu Gly Ser Val Ala
      50                  55                  60                
 Ala Phe Gly Ser Trp Ala Ser Arg Ile Pro Pro Leu Ser Arg Ile Cys
  65                  70                  75                  80
 Arg Gly Lys Thr Phe Pro Ser Ile His Leu Trp Thr Arg Leu Leu Ser
                  85                  90                  95    
 Ala Leu Ala Gly Leu Leu Tyr Ala Ser Ala Ile Ala Ala His Asp Arg
             100                 105                 110        
 His Pro Glu Tyr Leu Leu Arg
         115                



      <210> 2679
      <211> 188
      <212> PRT
      <213> Homo sapiens


      <400> 2679
 Ser Tyr Tyr Glu Arg Ile Asn Arg Gln Leu Ile Glu Ala Lys Met Ala
   1               5                  10                  15    
 Leu Gln Asp Arg Glu Glu Lys Met Glu Lys Val Phe Asp Asp Ile Glu
              20                  25                  30        
 Thr Asn Met Asn Leu Ile Gly Ala Thr Ala Val Glu Asp Lys Leu Gln
          35                  40                  45            
 Asp Gln Ala Ala Glu Thr Ile Glu Ala Leu His Ala Ala Gly Leu Lys
      50                  55                  60                
 Val Trp Val Leu Thr Gly Asp Lys Met Glu Thr Ala Lys Ser Thr Cys
  65                  70                  75                  80
 Tyr Ala Cys Arg Leu Phe Gln Thr Asn Thr Glu Leu Leu Glu Leu Thr
                  85                  90                  95    
 Thr Lys Thr Ile Glu Glu Ser Glu Arg Lys Glu Asp Arg Leu His Glu
             100                 105                 110        
 Leu Leu Ile Glu Tyr Arg Lys Lys Leu Leu His Glu Phe Pro Lys Ser
         115                 120                 125            
 Thr Arg Ser Phe Lys Lys Ala Trp Thr Glu His Gln Glu Tyr Gly Leu
     130                 135                 140                
 Ile Ile Asp Gly Ser Thr Leu Ser Leu Ile Leu Asn Ser Ser Gln Asp
 145                 150                 155                 160
 Ser Ser Ser Asn Asn Tyr Lys Ser Ile Phe Leu Gln Ile Cys Met Lys
                 165                 170                 175    
 Cys Thr Ala Val Leu Cys Cys Arg Met Ala Pro Leu
             180                 185            



      <210> 2680
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 2680
 Ser Ser Arg Trp Ala Phe Gln Val Leu Ser Pro Ser Ala Asp Ser Ala
   1               5                  10                  15    
 Arg Leu Pro Gly Arg Ala Pro Gly Asp Arg Asp Cys Thr Phe Gln Pro
              20                  25                  30        
 Ser Ala Pro Ala Pro Ser Lys Pro Phe Leu Leu Ser Thr Pro Pro Phe
          35                  40                  45            
 Tyr Ser Ala Cys Cys Gly Gly Ser Cys Arg Arg Pro Ala Ser Ser Thr
      50                  55                  60                
 Ala Phe Pro Arg Glu Glu Ser Met Leu Pro Leu Leu Thr Gln Asp Ser
  65                  70                  75                  80
 Asn Ser Lys Ala Arg Arg Gly Ile Leu Arg Arg Ala Val Phe Ser Glu
                  85                  90                  95    
 Asp Gln Arg Lys Ala Leu Glu Lys Met Phe His Lys Gln Lys Tyr Ile
             100                 105                 110        
 Ser Lys Thr Asp Arg Lys Lys Leu Ala Ile Asn Leu Gly Leu Lys Glu
         115                 120                 125            
 Ser Gln
     130



      <210> 2681
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 2681
 Glu Pro Gly Asp Pro Arg Glu Gly Glu Glu Glu Glu Glu Glu Asp Glu
   1               5                  10                  15    
 Pro Asp Pro Glu Ala Pro Glu Asn Gly Ser Leu Pro Arg Phe Val Pro
              20                  25                  30        
 Arg Phe Asn Phe Ser Leu Lys Asp Leu Thr Arg Phe Val Asp Phe Asn
          35                  40                  45            
 Ile Lys Gly Arg Asp Val Ile Val Phe Leu His Ile Gln Lys Thr Gly
      50                  55                  60                
 Gly Thr Ala Phe Gly Arg His Leu Val Lys Asn Ile Arg Leu Glu Gln
  65                  70                  75                  80
 Pro Cys Ser Cys Lys Ala Gly Gln Lys Lys Cys Thr Cys His Arg Pro
                  85                  90                  95    
 Gly Lys Lys Glu Thr Trp Leu Phe Ser Arg Phe Ser Thr Gly Trp Ser
             100                 105                 110        
 Cys Gly Leu His Ala Asp Trp Thr Glu
         115                 120    



      <210> 2682
      <211> 307
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(307)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2682
 Leu Gln Leu Cys Ser Met Trp Leu Leu Arg Ser Trp Val Gln Ala Glu
   1               5                  10                  15    
 Gly Ala Val Ser Ile Ser Asp Ser Pro Phe Ser Leu His Gln Cys Trp
              20                  25                  30        
 Ala Val Leu His Lys Ala Trp Cys Val Phe Leu Gln Leu Pro Gly Gly
          35                  40                  45            
 Phe Thr Phe Thr Leu Asn Pro Leu Ser Asp Asn Leu Leu Gly Lys Arg
      50                  55                  60                
 Val Asp Ser Ala Pro Ser Trp Gly Pro Leu Gly Ser Ala Phe Arg Gly
  65                  70                  75                  80
 Val His Met Pro Cys Val Gly Ala Ala Trp Glu Gly Lys Gly Pro Asn
                  85                  90                  95    
 Leu Leu Arg Pro Ser Gly Lys Leu Gly Pro Ser Gly Ser Arg Pro Thr
             100                 105                 110        
 Pro Ile Gly Gln Gln Gln Leu Pro Glu Val Pro Arg Ala Lys Gly Pro
         115                 120                 125            
 Leu Gly Pro Ala Ala Val Ile Cys Gln His Met Pro Ala Pro Ser Thr
     130                 135                 140                
 Gly Gly Lys Arg Gly Ser Phe Ser Gly Arg Tyr Leu Ser Ala Ser Leu
 145                 150                 155                 160
 Glu Leu Gly Gly Leu Pro Met Ala Pro Thr Gly Pro Ser Ala Leu Ser
                 165                 170                 175    
 Ala Pro Pro Ser Val Ser Arg Gly Ala Arg Xaa Ser Thr Arg Glu Lys
             180                 185                 190        
 Pro Gly Val Tyr Ala Ser Ala Thr Xaa Ala Ala Glu Ile Arg Glu Gly
         195                 200                 205            
 Gln Ala Leu Gly Gly Pro Arg Pro Ser Arg Asn Gly Ser Gly Gly Pro
     210                 215                 220                
 Leu Gly Pro Asp Phe Gly Pro Asn Gly Pro Lys Leu Arg Arg Ser Lys
 225                 230                 235                 240
 Ala Gly Cys Pro Trp Trp His Leu Ser Ser Val Asp Ala Gly Glu Xaa
                 245                 250                 255    
 Leu Trp Lys Gln His Ser Thr Ala Val Phe Ser Met Pro Gly Thr Gln
             260                 265                 270        
 Pro Pro Trp Arg Gly Leu Ile Thr Met Pro Ile Ser Pro Arg Gly Thr
         275                 280                 285            
 Glu Pro Thr Ala His Pro Gly Pro Arg Ser Pro Gly Leu Ala Tyr Ser
     290                 295                 300                
 Leu Thr Ala
 305        



      <210> 2683
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 2683
 Asn Arg Leu Thr Thr His Ser Pro His Ser Pro Gly Pro Gly Gly Arg
   1               5                  10                  15    
 Gln Ala Pro Trp Arg Arg Gln Cys Arg Pro Ala Ser Cys Pro Ala Lys
              20                  25                  30        
 Ser Thr Thr Trp Pro Val Thr Arg Ala Pro Thr Arg Pro Pro Ala Trp
          35                  40                  45            
 Pro Pro Pro Ala Ser Ala Pro Pro Arg Tyr Leu Leu Glu Glu Trp Phe
      50                  55                  60                
 Gln Asn Cys Tyr Ala Arg Tyr His Gln Ala Phe Ala Asp Arg Asp Gln
  65                  70                  75                  80
 Ser Glu Arg Gln Arg His Glu Ser Gln Gln Leu Ala Thr Glu Thr Gln
                  85                  90                  95    
 Ala Leu Ala Gln Arg Thr Gln Gln Asp Ser Thr Arg Thr Val Gly Glu
             100                 105                 110        
 Arg Leu Gln Asp Thr His Ser Trp Lys Ser Glu Leu Gln Arg Glu Met
         115                 120                 125            
 Glu Ala Leu Ala Ala Glu Thr Asn Leu Leu Leu
     130                 135                



      <210> 2684
      <211> 334
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(334)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2684
 Thr Pro Thr Thr Ser Gly Arg Thr Arg Lys Met Trp Pro Arg Pro Gly
   1               5                  10                  15    
 Thr Xaa Pro Pro Ala Asn Cys Ser Ala Asn Ile Asn Leu Thr His Gln
              20                  25                  30        
 Pro Trp Phe Gln Val Leu Glu Pro Gln Phe Arg Gln Phe Leu Phe Tyr
          35                  40                  45            
 Arg His Cys Arg Tyr Phe Pro Met Leu Leu Asn His Pro Glu Lys Cys
      50                  55                  60                
 Arg Gly Asp Val Tyr Leu Leu Val Val Val Lys Ser Val Ile Thr Gln
  65                  70                  75                  80
 His Asp Arg Arg Glu Ala Ile Arg Gln Thr Trp Ala Arg Ala Ala Val
                  85                  90                  95    
 Arg Gly Trp Gly Pro Ser Ala Val Arg Thr Leu Phe Leu Leu Gly Thr
             100                 105                 110        
 Ala Ser Lys Gln Glu Glu Arg Thr His Tyr Gln Gln Leu Leu Ala Tyr
         115                 120                 125            
 Glu Asp Ala Leu Tyr Gly Asp Ile Leu Gln Trp Gly Phe Leu Asp Thr
     130                 135                 140                
 Phe Phe Asn Leu Thr Leu Lys Glu Ile His Phe Leu Lys Trp Leu Asp
 145                 150                 155                 160
 Ile Tyr Cys Pro His Val Pro Phe Ile Phe Lys Gly Asp Asp Asp Val
                 165                 170                 175    
 Phe Val Asn Pro Thr Asn Leu Leu Glu Phe Leu Ala Asp Arg Gln Pro
             180                 185                 190        
 Gln Glu Asn Leu Phe Val Gly Asp Val Leu Gln His Ala Arg Pro Ile
         195                 200                 205            
 Arg Arg Lys Asp Asn Lys Tyr Tyr Ile Pro Gly Ala Leu Tyr Gly Lys
     210                 215                 220                
 Ala Ser Tyr Pro Pro Tyr Ala Gly Gly Gly Gly Phe Leu Met Ala Gly
 225                 230                 235                 240
 Ser Leu Ala Arg Arg Leu His His Ala Cys Asp Thr Leu Glu Leu Tyr
                 245                 250                 255    
 Pro Ile Asp Asp Val Phe Leu Gly Met Cys Leu Glu Val Leu Gly Val
             260                 265                 270        
 Gln Pro Thr Ala His Glu Gly Phe Lys Thr Phe Gly Ile Ser Arg Asn
         275                 280                 285            
 Arg Asn Ser Arg Met Asn Lys Glu Pro Cys Phe Phe Arg Ala Met Leu
     290                 295                 300                
 Val Val His Lys Leu Leu Pro Pro Glu Leu Leu Ala Met Trp Gly Leu
 305                 310                 315                 320
 Val His Ser Asn Leu Thr Cys Ser Arg Lys Leu Gln Val Leu
                 325                 330                



      <210> 2685
      <211> 247
      <212> PRT
      <213> Homo sapiens


      <400> 2685
 Val Arg Ser Met Ser Cys Pro Pro Ser Trp Pro Tyr Cys Ala Pro Cys
   1               5                  10                  15    
 Pro Thr Asn Ile Gly Glu Ser Thr Ser Pro Leu Arg Lys Thr Ile Glu
              20                  25                  30        
 Thr Pro Thr Leu Trp Asp Pro Lys Ala Pro Ser Cys Ser Leu Glu Leu
          35                  40                  45            
 Pro Pro Trp Val Leu Ala Ser Pro Gln Arg Ser Arg Gly Thr Ala Leu
      50                  55                  60                
 Pro Phe Leu Pro Ser Asn Val Leu Pro Ser Leu Ala Leu Pro Ser Thr
  65                  70                  75                  80
 Ser Phe Leu Cys Arg Pro Leu Leu Ser His Leu Val Thr Ser Leu Leu
                  85                  90                  95    
 Ala Gly Pro Gly Ala His Asp Gly His Leu Arg Lys Glu Gly Trp Arg
             100                 105                 110        
 Ser Thr Pro Glu Met Thr Ser Leu Pro Ala Pro Glu His Pro Ala Ser
         115                 120                 125            
 Pro Cys Asp Ser Val Leu Cys Ser Pro Asp Val Ser Met Cys Thr Leu
     130                 135                 140                
 Gly Pro Ala Ala Arg Trp Asp Ala Gln Ala Lys Ser Ala Pro Leu Pro
 145                 150                 155                 160
 Pro Cys Cys Thr Asp Cys Lys Ser Phe Pro His Leu Gln Arg Pro Trp
                 165                 170                 175    
 Ala Gln Pro His Thr Ser Gln Ala Thr Ser Val Asp Ser Gly Glu Ala
             180                 185                 190        
 Gly Thr Lys Gly Met Ser Gln Phe Thr Val Trp Thr Trp Trp Arg Ser
         195                 200                 205            
 Arg Pro Cys Glu Thr Arg Gln Gly Glu Gly Ile Gly Asn Trp Gly Tyr
     210                 215                 220                
 Ser Val Thr Pro Gly Pro Pro Gly Ser Gln Asn Leu Pro Ala Arg Leu
 225                 230                 235                 240
 Asp Gly Gln Gly Leu Ala Ser
                 245        



      <210> 2686
      <211> 96
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(96)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2686
 Thr Phe Cys Pro Arg Cys Gly Cys Pro Ser Gly Leu Ala Met Arg Leu
   1               5                  10                  15    
 Phe Leu Ser Leu Pro Val Leu Val Val Val Leu Ser Ile Val Leu Glu
              20                  25                  30        
 Gly Pro Ala Pro Ala Xaa Gly Ala Pro Glu Val Ser Asn Pro Phe Asp
          35                  40                  45            
 Gly Leu Glu Glu Leu Gly Lys Thr Leu Glu Asp Tyr Thr Arg Glu Phe
      50                  55                  60                
 Ile Asn Arg Ile Thr Gln Ser Glu Leu Pro Ala Lys Met Trp Asp Trp
  65                  70                  75                  80
 Phe Ser Glu Thr Phe Arg Lys Val Lys Glu Lys Leu Lys Thr Asp Ser
                  85                  90                  95    





      <210> 2687
      <211> 1263
      <212> PRT
      <213> Homo sapiens


      <400> 2687
 Pro Arg Gly Pro Arg Pro Gly Ala Ser Gly Ser Ala Met Trp Leu Ser
   1               5                  10                  15    
 Pro Glu Glu Val Leu Val Ala Asn Ala Leu Trp Val Thr Glu Arg Ala
              20                  25                  30        
 Asn Pro Phe Phe Val Leu Arg Arg Arg Arg Gly His Gly Arg Gly Gly
          35                  40                  45            
 Gly Leu Thr Gly Leu Leu Val Gly Thr Leu Asp Val Val Leu Asp Ser
      50                  55                  60                
 Ser Ala Arg Val Ala Pro Tyr Arg Ile Leu His Gln Thr Gln Asp Ser
  65                  70                  75                  80
 Gln Val Tyr Trp Thr Val Ala Cys Gly Ser Ser Arg Lys Glu Ile Thr
                  85                  90                  95    
 Lys His Trp Glu Trp Leu Glu Asn Asn Leu Leu Gln Thr Leu Ser Ile
             100                 105                 110        
 Phe Asp Ser Glu Glu Asp Ile Thr Thr Phe Val Lys Gly Lys Ile His
         115                 120                 125            
 Gly Ile Ile Ala Glu Glu Asn Lys Asn Leu Gln Pro Gln Gly Asp Glu
     130                 135                 140                
 Asp Pro Gly Lys Phe Lys Glu Ala Glu Leu Lys Met Arg Lys Gln Phe
 145                 150                 155                 160
 Gly Met Pro Glu Gly Glu Lys Leu Val Asn Tyr Tyr Ser Cys Ser Tyr
                 165                 170                 175    
 Trp Lys Gly Arg Val Pro Arg Gln Gly Trp Leu Tyr Leu Thr Val Asn
             180                 185                 190        
 His Leu Cys Phe Tyr Ser Phe Leu Leu Gly Lys Glu Val Ser Leu Val
         195                 200                 205            
 Val Gln Trp Val Asp Ile Thr Arg Leu Glu Lys Asn Ala Thr Leu Leu
     210                 215                 220                
 Phe Pro Glu Ser Ile Arg Val Asp Thr Arg Asp Gln Glu Leu Phe Phe
 225                 230                 235                 240
 Ser Met Phe Leu Asn Ile Gly Glu Thr Phe Lys Leu Met Glu Gln Leu
                 245                 250                 255    
 Ala Asn Leu Ala Met Arg Gln Leu Leu Asp Ser Glu Gly Phe Leu Glu
             260                 265                 270        
 Asp Lys Ala Leu Pro Arg Pro Ile Arg Pro His Arg Asn Ile Ser Ala
         275                 280                 285            
 Leu Lys Arg Asp Leu Asp Ala Arg Ala Lys Asn Glu Cys Tyr Arg Ala
     290                 295                 300                
 Thr Phe Arg Leu Pro Arg Asp Glu Arg Leu Asp Gly His Thr Ser Cys
 305                 310                 315                 320
 Thr Leu Trp Thr Pro Phe Asn Lys Leu His Ile Pro Gly Gln Met Phe
                 325                 330                 335    
 Ile Ser Asn Asn Tyr Ile Cys Phe Ala Ser Lys Glu Glu Asp Ala Cys
             340                 345                 350        
 His Leu Ile Ile Pro Leu Arg Glu Val Thr Ile Val Glu Lys Ala Asp
         355                 360                 365            
 Ser Ser Ser Val Leu Pro Ser Pro Leu Ser Ile Ser Thr Lys Ser Lys
     370                 375                 380                
 Met Thr Phe Leu Phe Ala Asn Leu Lys Asp Arg Asp Phe Leu Val Gln
 385                 390                 395                 400
 Arg Ile Ser Asp Phe Leu Gln Lys Thr Pro Ser Lys Gln Pro Gly Ser
                 405                 410                 415    
 Ile Gly Ser Arg Lys Ala Ser Val Val Asp Pro Ser Thr Glu Ser Ser
             420                 425                 430        
 Pro Ala Pro Gln Glu Gly Ser Glu Gln Pro Ala Ser Pro Ala Ser Pro
         435                 440                 445            
 Leu Ser Ser Arg Gln Ser Phe Cys Ala Gln Glu Ala Pro Thr Ala Ser
     450                 455                 460                
 Gln Gly Leu Leu Lys Leu Phe Gln Lys Asn Ser Pro Met Glu Asp Leu
 465                 470                 475                 480
 Gly Ala Lys Gly Ala Lys Glu Lys Met Lys Glu Glu Ser Trp His Ile
                 485                 490                 495    
 His Phe Phe Glu Tyr Gly Arg Gly Val Cys Met Tyr Arg Thr Ala Lys
             500                 505                 510        
 Thr Arg Ala Leu Val Leu Lys Gly Ile Pro Glu Ser Leu Arg Gly Glu
         515                 520                 525            
 Leu Trp Leu Leu Phe Ser Gly Ala Trp Asn Glu Met Val Thr His Pro
     530                 535                 540                
 Gly Tyr Tyr Ala Glu Leu Val Glu Lys Ser Thr Gly Lys Tyr Ser Leu
 545                 550                 555                 560
 Ala Thr Glu Glu Ile Glu Arg Asp Leu His Arg Ser Met Pro Glu His
                 565                 570                 575    
 Pro Ala Phe Gln Asn Glu Leu Gly Ile Ala Ala Leu Arg Arg Val Leu
             580                 585                 590        
 Thr Ala Tyr Ala Phe Arg Asn Pro Thr Ile Gly Tyr Cys Gln Ala Met
         595                 600                 605            
 Asn Ile Val Thr Ser Val Leu Leu Leu Tyr Gly Ser Glu Glu Glu Ala
     610                 615                 620                
 Phe Trp Leu Leu Val Ala Leu Cys Glu Arg Met Leu Pro Asp Tyr Tyr
 625                 630                 635                 640
 Asn Thr Arg Val Val Gly Ala Leu Val Asp Gln Gly Ile Phe Glu Glu
                 645                 650                 655    
 Leu Thr Arg Asp Phe Leu Pro Gln Leu Ser Glu Lys Met Gln Asp Leu
             660                 665                 670        
 Gly Val Ile Ser Ser Ile Ser Leu Ser Trp Phe Leu Thr Leu Phe Leu
         675                 680                 685            
 Ser Val Met Pro Phe Glu Ser Ala Val Val Ile Val Asp Cys Phe Phe
     690                 695                 700                
 Tyr Glu Gly Ile Lys Val Ile Leu Gln Val Ala Leu Ala Val Leu Asp
 705                 710                 715                 720
 Ala Asn Met Glu His Leu Leu Gly Cys Ser Asp Glu Gly Glu Ala Met
                 725                 730                 735    
 Thr Met Leu Gly Arg Tyr Leu Asp Asn Val Val Asn Lys Gln Ser Val
             740                 745                 750        
 Ser Pro Pro Ile Pro His Leu Arg Ala Leu Leu Ser Ser Ser Asp Asp
         755                 760                 765            
 Pro Pro Ala Glu Val Asp Ile Phe Glu Leu Leu Lys Val Ser Tyr Glu
     770                 775                 780                
 Lys Phe Ser Ser Leu Arg Ala Glu Asp Ile Glu Gln Met Arg Phe Lys
 785                 790                 795                 800
 Gln Arg Leu Lys Val Ile Gln Ser Leu Glu Asp Thr Ala Lys Arg Ser
                 805                 810                 815    
 Val Val Arg Ala Ile Pro Val Asp Ile Gly Phe Ser Ile Glu Glu Leu
             820                 825                 830        
 Glu Asp Leu Tyr Met Val Phe Lys Ala Lys His Leu Ala Ser Gln Tyr
         835                 840                 845            
 Trp Gly Cys Ser Arg Thr Met Ala Gly Arg Arg Asp Pro Ser Leu Pro
     850                 855                 860                
 Tyr Leu Glu Gln Tyr Arg Ile Asp Ala Ser Gln Phe Arg Glu Leu Phe
 865                 870                 875                 880
 Ala Ser Leu Thr Pro Trp Ala Cys Gly Ser His Thr Pro Leu Leu Ala
                 885                 890                 895    
 Gly Arg Met Phe Arg Leu Leu Asp Glu Asn Lys Asp Ser Leu Ile Asn
             900                 905                 910        
 Phe Lys Glu Phe Val Thr Gly Met Ser Gly Met Tyr His Gly Asp Leu
         915                 920                 925            
 Thr Glu Lys Leu Lys Val Leu Tyr Lys Leu His Leu Pro Pro Ala Leu
     930                 935                 940                
 Ser Pro Glu Glu Ala Glu Ser Ala Leu Glu Ala Thr His Leu Phe Ser
 945                 950                 955                 960
 Gln Arg Asp Ser Ser Ser Glu Ala Ser Pro Leu Ala Ser Asp Leu Asp
                 965                 970                 975    
 Leu Phe Leu Pro Trp Glu Ala Gln Glu Ala Leu Pro Gln Glu Glu Gln
             980                 985                 990        
 Glu Gly Ser Gly Ser Glu Glu Arg Gly Glu Glu Lys Gly Thr Ser Ser
         995                1000                1005            
 Pro Asp Tyr Arg His Tyr Leu Arg Met Trp Ala Lys Glu Lys Glu Ala
    1010                1015                1020                
 Gln Lys Glu Thr Ile Lys Asp Leu Pro Lys Met Asn Gln Glu Gln Phe
1025                1030                1035                1040
 Ile Glu Leu Cys Lys Thr Leu Tyr Asn Met Phe Ser Glu Asp Pro Met
                1045                1050                1055    
 Glu Gln Asp Leu Tyr His Ala Ile Ala Thr Val Ala Ser Leu Leu Leu
            1060                1065                1070        
 Arg Ile Gly Glu Val Gly Lys Lys Phe Ser Ala Arg Thr Gly Arg Lys
        1075                1080                1085            
 Pro Arg Asp Cys Ala Thr Glu Glu Asp Glu Pro Pro Ala Pro Glu Leu
    1090                1095                1100                
 His Gln Asp Ala Ala Arg Glu Leu Gln Pro Pro Ala Ala Gly Asp Pro
1105                1110                1115                1120
 Gln Ala Lys Ala Gly Gly Asp Thr His Leu Gly Lys Ala Pro Gln Glu
                1125                1130                1135    
 Ser Gln Val Val Val Glu Gly Gly Ser Gly Glu Gly Gln Gly Ser Pro
            1140                1145                1150        
 Ser Gln Leu Leu Ser Asp Asp Glu Thr Lys Asp Asp Met Ser Met Ser
        1155                1160                1165            
 Ser Tyr Ser Val Val Ser Thr Gly Ser Leu Gln Cys Glu Asp Leu Ala
    1170                1175                1180                
 Asp Asp Thr Val Leu Val Gly Gly Glu Ala Cys Ser Pro Thr Ala Arg
1185                1190                1195                1200
 Ile Gly Gly Thr Val Asp Thr Asp Trp Cys Ile Ser Phe Glu Gln Ile
                1205                1210                1215    
 Leu Ala Ser Ile Leu Thr Glu Ser Val Leu Val Asn Phe Phe Glu Lys
            1220                1225                1230        
 Arg Val Asp Ile Gly Leu Lys Ile Lys Asp Gln Lys Lys Val Glu Arg
        1235                1240                1245            
 Gln Phe Ser Thr Ala Ser Asp His Glu Gln Pro Gly Val Ser Gly
    1250                1255                1260            



      <210> 2688
      <211> 187
      <212> PRT
      <213> Homo sapiens


      <400> 2688
 Gly Asp Lys Gly Ala Asp Glu Arg Glu Ile Ser Gly Gly Thr Asp Thr
   1               5                  10                  15    
 Ala Ala Ala Ala Gln Leu Lys Ile His Tyr Trp Ile Pro Gly Pro Ser
              20                  25                  30        
 Thr Val Gln Glu His Lys Glu Val Phe Asn Thr Lys Leu Ala Asp Gly
          35                  40                  45            
 Gln Asn Gly Ser Pro Ser Lys Gln Ala Ser Ile Cys Asp Arg Gln Phe
      50                  55                  60                
 Val Val Ala Gly Gly Tyr His Arg Ser Leu Ala Asp Glu Ala Tyr Gly
  65                  70                  75                  80
 Asp Glu Glu Asp Leu Pro Lys Val Val Gly Leu Val His Ser Thr Arg
                  85                  90                  95    
 Gly Pro Ala His Pro Thr Tyr Leu Leu Arg Pro Leu Gln Lys Asp Gln
             100                 105                 110        
 Asp Ser Ser Leu Leu Arg Ala Ser Gly Gly Gly Gly Gly Ser Pro Ser
         115                 120                 125            
 Ser Ser Thr Lys Ser Glu His Ser Cys Arg Gln Ile His Ile Pro Gly
     130                 135                 140                
 Pro Phe Ser His Ala Asp Ile Thr Gly Gln Lys Trp Phe Pro Gly Gly
 145                 150                 155                 160
 Val Ser Thr Glu Pro Ala Arg Asn Met Gly Phe Leu Lys Pro Thr Pro
                 165                 170                 175    
 Thr Pro Leu Leu Arg Ser Pro Lys Asp Phe Arg
             180                 185        



      <210> 2689
      <211> 907
      <212> PRT
      <213> Homo sapiens


      <400> 2689
 Met Ala Gly Ala Arg Val Gly Pro Ala Ala Gly Ala Arg Thr Ala Val
   1               5                  10                  15    
 Pro Ala Ala Gly Glu Val Pro Ala Ser Pro Ala Leu Thr Asp Thr Gln
              20                  25                  30        
 Lys Gly Thr Gly Ile Gly His Trp Val Val Ala Val Ala Pro Thr Ile
          35                  40                  45            
 Gln Thr Ser Val Trp Pro Lys Pro Phe Arg Gly Asn Arg Ile Ser Val
      50                  55                  60                
 Leu Gly Phe Glu Pro His Ser Leu Val Ser Ala Asp Pro Gln Gln Ser
  65                  70                  75                  80
 Gln Tyr Pro Tyr Phe Leu Phe Pro Glu Pro Pro Ser Pro Lys Pro Leu
                  85                  90                  95    
 Ser Met Leu Glu Asp Ser Tyr Ala Ser Leu Lys Ile Gln Ala Ser Ala
             100                 105                 110        
 Arg Ala Pro Pro Leu Ser Pro Ile Asp Met Asp Lys Gln Glu Arg Ile
         115                 120                 125            
 Lys Ala Glu Arg Lys Arg Leu Arg Asn Arg Ile Ala Ala Ser Gln Val
     130                 135                 140                
 Pro Gln Ala Gln Ala Gly Ala His Leu Ala Pro Gly Lys Lys Val Lys
 145                 150                 155                 160
 Thr Leu Lys Ser Gln Asn Thr Glu Leu Ala Ser Thr Ala Ala Cys Cys
                 165                 170                 175    
 Ala Ser Ser Ser Ser Leu Val Gly Gly Ser Arg Glu Arg Val Ser Glu
             180                 185                 190        
 Ser Gly Pro His Ile Cys Ala Gln Arg Ala Pro Pro Arg Arg Ala Leu
         195                 200                 205            
 Ala Arg Gly Arg Leu Met Pro Gly Asp Thr Gly Pro Arg Glu Leu His
     210                 215                 220                
 Arg Asn Pro Ser Val Val Val Val Val Cys Leu Leu Val Ser Leu Leu
 225                 230                 235                 240
 Leu Ile Gly Ser Val Val Met Ala Val Arg Phe Cys His Arg Asn Glu
                 245                 250                 255    
 Ser Lys Phe Glu Asn Leu Asp Glu Val Ser Met Gly Ser Val Asn Asp
             260                 265                 270        
 Arg Leu Ser Phe Ala His His Leu Gln Glu His Gln Phe Leu Phe Pro
         275                 280                 285            
 Arg Val Ala Gly Cys Arg Ala Arg Gly Thr Pro Ala Thr Pro Ala Ala
     290                 295                 300                
 Leu Gly Arg Cys Trp Pro Trp Pro Leu Arg Pro Pro Cys Pro Ala Ser
 305                 310                 315                 320
 Gln Arg Gln Lys Val Ala Val Gly Pro Lys Arg Met Gly Pro Ser Pro
                 325                 330                 335    
 Phe Arg Leu Ala Ala Thr Val Arg Gln Pro Glu Arg Pro Gln Ala Pro
             340                 345                 350        
 Met Ala Val Pro Ser Cys Pro Ser Thr Pro Asp Tyr Glu Asn Met Phe
         355                 360                 365            
 Val Ala Ser Gln Gln Pro Ser Thr Ser Gly Met Asn Lys Gly Lys Ala
     370                 375                 380                
 Leu Pro Ala Gly Ile Leu Gln Met Val Thr Asp Thr Ser Arg Pro Asn
 385                 390                 395                 400
 Val Gly Gly Asp Glu Ser Leu Asp Cys Leu Val Leu Asn Arg Ile Ser
                 405                 410                 415    
 Tyr Thr Cys Arg Ser Thr Leu Ser Pro Arg Pro Ser Phe Ser Ala Pro
             420                 425                 430        
 Gly Arg Glu Glu Ser Gly Ser Val Met Ala Pro Asp Asp Ser Met Gly
         435                 440                 445            
 Ile Met Arg Ser Leu Gly Gly Leu Ser Arg Leu Thr Val Ala Ala Ile
     450                 455                 460                
 Val Arg Asp Val Thr Lys Phe Cys Asp Pro Gly Pro Pro His Pro Ala
 465                 470                 475                 480
 Leu Gln Glu Thr Pro Gln Met Ala Pro Ser Pro Gly Ala Pro Gln Pro
                 485                 490                 495    
 Leu Asn Pro Pro Ala Pro Pro Arg Lys Arg Asn Thr Ala Ser Ala Pro
             500                 505                 510        
 Val His Leu Arg Ala Ala Arg Asp Asp Ser Glu Ala Ala Leu Tyr Pro
         515                 520                 525            
 Phe Leu Gln Val Ser Tyr Ser Leu Ser Gly His Lys Asn Asn Tyr Thr
     530                 535                 540                
 Tyr Tyr Ala Trp Val Val Gly Gly Phe Arg Ala Leu Gly Tyr Lys His
 545                 550                 555                 560
 Ser Thr Asp Val Cys Ser Gly Val Thr Ile Gln Glu Glu Met Trp Ile
                 565                 570                 575    
 Arg His Arg Phe Leu Arg Ala Ala Pro Ile Ser Gln Arg Thr Arg His
             580                 585                 590        
 Tyr His Arg Phe Leu Gly Cys Ser Met Ala Gly Ser Gly Cys Ala Ser
         595                 600                 605            
 Asp Leu Leu Cys Cys Asp Trp Arg Asp Ser Cys Cys Arg Cys Ser Leu
     610                 615                 620                
 Ser Ala Ala Gln Ala Thr Pro Leu Ser Ser Pro Arg Pro Arg Pro Arg
 625                 630                 635                 640
 Ser Ala Ala Arg Leu Ser Ala Arg Gly Ala Ala Thr Thr Ala Gly Ser
                 645                 650                 655    
 Val Cys Ser Gly Gly Gly Glu Val Ala Gly Glu Pro Gly Pro Arg Arg
             660                 665                 670        
 His His Val Gly Gly Ala Glu Lys Trp Gly Asp Val Gln Trp Thr Pro
         675                 680                 685            
 Gly Asp Cys Asp Asn Trp Met Asn Ile Asn Leu Arg Glu Val Ile Cys
     690                 695                 700                
 Thr Ser Gly Thr Gly Gln Val Leu Ala Asp Ala Arg Val Leu His Pro
 705                 710                 715                 720
 Arg Gln His His Gln Tyr Leu Arg Ile Pro Asp Glu Ile Ile Asp Met
                 725                 730                 735    
 Val Lys Glu Glu Val Gly Pro Arg Ala Ala Ala Ala Glu Ala Cys Ser
             740                 745                 750        
 Ser Arg Ser Ser Arg Lys Pro Arg His Gly Arg Arg Trp Pro Arg Cys
         755                 760                 765            
 Phe Gly Ala Leu Ser Cys Cys Gly Gly Arg Glu Ser Asp Ser Thr Cys
     770                 775                 780                
 Cys Lys Pro Leu Pro Phe Ala Asp Pro Gln Val Leu His Ala Pro Glu
 785                 790                 795                 800
 Lys Gly Val Trp Glu Ala Gly Ser Arg Thr Arg Pro Arg Glu Arg Ala
                 805                 810                 815    
 Pro Arg Ser Val Cys Pro Gly Ser Gly Pro Gly Pro Gly Val Glu Ala
             820                 825                 830        
 Thr Ala Arg Ser Cys Arg Ala Gly Gly Ala Glu Ala Val Glu Gly Gly
         835                 840                 845            
 Thr Gly Ala Gln Ala Ser Met Val Asn Thr Thr Gly Tyr Trp Ala Arg
     850                 855                 860                
 Pro Leu Gln Ala Thr Gln Gly Gly Ser Ala Ala Trp Gln Gln Trp Gly
 865                 870                 875                 880
 Thr Arg Glu Ala Ser Pro Asp Asp Thr Thr Thr Arg Gly Leu Thr Gly
                 885                 890                 895    
 Ala Lys Pro Glu Ser Thr Asn Ser Gln Asn His
             900                 905        



      <210> 2690
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 2690
 Ser Arg Lys Gly Ser Ser Leu Ala Ala His Pro Leu Ser Pro Ser Arg
   1               5                  10                  15    
 Leu Ser Ala Val Pro Thr Ala Gly Gly Gly Gly Asp Ser Glu Ala Lys
              20                  25                  30        
 Pro His Leu Val Ser Pro Gly Gly Ser Glu Gly Ala Ile Trp Cys Gly
          35                  40                  45            
 His Gly Gln Gly Arg Gly Gly Ser Gly Asn Asp Arg Gly Gly Gln Gly
      50                  55                  60                
 Pro Gly Ala Gly Gly Arg Arg Gly Ile Pro Thr Pro Ala Arg Gly Ala
  65                  70                  75                  80
 Val Ile Tyr Lys Thr Gln Arg Arg Glu Glu Glu Gly Thr Arg Gly Cys
                  85                  90                  95    
 Asn Gln Leu Ala Ser Leu Ser Gly Pro Gln Gly Ala Thr Val Ser Pro
             100                 105                 110        
 Ser Ser Gly Gly Ser Ser Pro Gly Thr Cys Cys Asp Arg His Pro Leu
         115                 120                 125            
 Arg Ala Asp Thr Arg Met Met Val Trp Gly Gln Glu Pro Ser Pro Ser
     130                 135                 140                
 Leu Val Cys Phe Pro Lys Leu Gln Pro Asp Ser Leu
 145                 150                 155    



      <210> 2691
      <211> 552
      <212> PRT
      <213> Homo sapiens


      <400> 2691
 Met Glu Thr Glu Pro Ser Lys Ala Lys Ala Asn Asp Pro Gly Ser Ala
   1               5                  10                  15    
 Ala Glu Gly Val Val Phe Ala Ser Ile Ser Ser Gly Leu Gly Glu Val
              20                  25                  30        
 Thr Phe Leu Ser Leu Thr Ala Phe Tyr Pro Arg Ala Val Ile Ser Trp
          35                  40                  45            
 Trp Ser Ser Gly Thr Gly Gly Ala Gly Leu Leu Gly Ala Leu Ser Tyr
      50                  55                  60                
 Leu Gly Leu Thr Gln Ala Gly Leu Ser Pro Gln Gln Thr Leu Leu Ser
  65                  70                  75                  80
 Met Leu Gly Ile Pro Ala Leu Leu Leu Ala Ser Ile Leu Arg Lys Ala
                  85                  90                  95    
 Leu Asp Lys Ile Ala Glu Ile Lys Ser Leu Leu Glu Glu Arg Arg Ile
             100                 105                 110        
 Gly His Lys Tyr Leu Gly Leu Arg Tyr Cys Pro Pro Leu Tyr Val Leu
         115                 120                 125            
 Tyr Thr Asp Ala Phe Trp Ser Val Thr Pro Tyr Ser Glu Val His Ile
     130                 135                 140                
 Ala Phe Thr Ile Leu Glu Glu Val Ser Leu Cys Asp Ser Lys Leu Ile
 145                 150                 155                 160
 His Ile Ile Phe Val Arg Leu Ala Tyr Ala Cys Pro Arg Phe Thr Val
                 165                 170                 175    
 Ser Ala Trp Ala Ala Ser Ile Pro Glu Tyr Met Val Arg Ile Ser Leu
             180                 185                 190        
 Leu Thr Ala Gln Val Asp Met Thr Ile Ile Gly Ile Ala Phe Met Pro
         195                 200                 205            
 Cys Pro Arg Pro Leu Met Pro Thr Val Ala Pro Thr Ala Ala Arg Glu
     210                 215                 220                
 Met Gly Val His His Thr Gly Asp Ser Ala Gly Glu Lys Leu His Arg
 225                 230                 235                 240
 Ala Cys Cys Gly Arg Gly Arg Leu Cys Arg Glu His Arg Val Leu Ala
                 245                 250                 255    
 Leu Pro Leu Ser Ser Thr Leu Pro Tyr Arg Asp Cys Ala Pro Gly Cys
             260                 265                 270        
 Ile Leu His Phe Pro Pro Phe Val His Arg Tyr Glu Val Asp Asp Ile
         275                 280                 285            
 Asp Glu Glu Gly Lys Ala Arg His Thr Val Ser Leu Arg Arg Ile Ile
     290                 295                 300                
 Pro Leu Thr Arg Trp Lys Ala Asn Pro Glu Thr Asp Pro Glu Ala Leu
 305                 310                 315                 320
 Leu Val Lys Glu Lys Thr Met Phe Ser Gly Cys Cys Asn Leu Gly Asp
                 325                 330                 335    
 Ser Thr Ala Asn Thr Gly Ser Leu Gly Asn Thr Ala Lys Trp Ala Arg
             340                 345                 350        
 Val Pro Asn Tyr Thr Asn Met Gln Arg Leu Val Val Ala Pro Asn Val
         355                 360                 365            
 Gly Leu Arg Cys Tyr Leu Leu Asp Thr Arg Leu Lys Gly Gln Gly Lys
     370                 375                 380                
 Glu Cys Glu Ser Pro Pro Met Ile Gly Leu Arg Ser Ile Cys Met His
 385                 390                 395                 400
 Thr Lys Lys Arg Val Ser Ser Phe Arg Gly Asn Lys Ile Gly Leu Lys
                 405                 410                 415    
 Asp Val Ile Thr Leu Arg Arg His Val Glu Thr Lys Val Arg Ala Lys
             420                 425                 430        
 Ile Arg Lys Arg Lys Val Thr Thr Lys Ile Asn Arg His Asp Lys Ile
         435                 440                 445            
 Asn Gly Lys Arg Lys Thr Ala Arg Lys Gln Leu Ser Leu Ser Pro Cys
     450                 455                 460                
 Ser Gln Cys Leu Asn Leu Val Phe Leu Leu Ala Asp Val Trp Phe Gly
 465                 470                 475                 480
 Phe Leu Pro Ser Ile Tyr Leu Val Phe Leu Ile Ile Leu Tyr Glu Gly
                 485                 490                 495    
 Leu Leu Gly Gly Ala Ala Tyr Val Asn Thr Phe His Asn Ile Ala Leu
             500                 505                 510        
 Glu Thr Ser Asp Glu His Arg Glu Phe Ala Met Ala Ala Thr Cys Ile
         515                 520                 525            
 Ser Asp Thr Leu Gly Ile Ser Leu Ser Gly Leu Leu Ala Leu Pro Leu
     530                 535                 540                
 His Asp Phe Leu Cys Gln Leu Ser
 545                 550        



      <210> 2692
      <211> 225
      <212> PRT
      <213> Homo sapiens


      <400> 2692
 Met Lys Thr Leu Leu Ala Arg Ala Ser Arg Phe Leu Ala Leu Pro Arg
   1               5                  10                  15    
 Thr Ser Phe Asn Ala Leu Ser Lys Ser His Asn Leu Leu Gly Phe Lys
              20                  25                  30        
 Asp Ile Arg Ser Asn Val Glu Ala Leu Ala Gln Lys Thr Gln Pro Ser
          35                  40                  45            
 Val Phe Pro Lys Glu Ser Val Gln Val Thr Pro Val Cys Tyr Thr Lys
      50                  55                  60                
 Gly Asp Arg Glu Ser Val Gln Lys Cys Pro Leu Ile Phe Arg Ser His
  65                  70                  75                  80
 Ser Ala Thr Glu Gln Val Ser Ile Arg Arg Gly Val Ile Val Arg Val
                  85                  90                  95    
 Ala Lys Trp Arg Gly Glu Ser His Ile His Gly Gly Pro Asp Val Pro
             100                 105                 110        
 Gly Leu Val Leu Asp Thr Ser Tyr Glu Thr Ser Pro Leu Ile His Thr
         115                 120                 125            
 Pro Ala Leu Arg Val Tyr Tyr Ile Gly Glu Asp Ile Ala Met Glu Gln
     130                 135                 140                
 Val Thr Asn Leu Ala Phe Pro Leu Leu Tyr Ser Asn Ser His Arg Val
 145                 150                 155                 160
 Ser Glu Pro Gly Glu Leu Gly Phe Trp Gly Pro Gly Glu Ser Val Met
                 165                 170                 175    
 Pro Ala Asp Ala Val Ser Val Pro Cys Thr Cys His Pro Gly Ser Tyr
             180                 185                 190        
 Gly Val Gln Pro Leu Val Leu Arg Ile Gln Gly Tyr Ser Gly Thr Gly
         195                 200                 205            
 Arg Trp Ile Ser Ala Ser Ala Met Ser Cys Ile Ile Ser Asp Arg Asn
     210                 215                 220                
 Gly
 225



      <210> 2693
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 2693
 Ala Leu Lys His Phe Cys Leu Cys Ser Leu Ile Phe Ser Val Thr Thr
   1               5                  10                  15    
 Met Lys Phe Leu Ala Val Leu Val Leu Leu Gly Val Ser Ile Phe Leu
              20                  25                  30        
 Val Ser Ala Gln Asn Pro Thr Thr Ala Ala Pro Ala Asp Thr Val Ser
          35                  40                  45            
 Ser Leu Leu Val Leu Leu Met Met Lys Pro Leu Asp Ala Glu Thr Thr
      50                  55                  60                
 Ala Ala Ala Thr Thr Ala Thr Thr Ala Ala Pro Thr Thr Ala Thr Thr
  65                  70                  75                  80
 Ala Ala Ser Thr Thr Ala Arg Lys Asp Ile Pro Val Leu Pro Lys Trp
                  85                  90                  95    
 Val Gly Asp Leu Pro Asn Arg
             100            



      <210> 2694
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 2694
 Arg Val Asp Pro Arg Val Arg Ala Pro Arg Cys Gly Asp Lys Ile Lys
   1               5                  10                  15    
 Asn His Met Tyr Lys Cys Asp Cys Gly Ser Leu Lys Asp Cys Ala Ser
              20                  25                  30        
 Asp Arg Cys Cys Glu Thr Ser Cys Thr Leu Ser Leu Gly Ser Val Cys
          35                  40                  45            
 Asn Thr Gly Leu Cys Cys His Lys Cys Lys Tyr Ala Ala Pro Gly Val
      50                  55                  60                
 Val Cys Arg Asp Leu Gly Gly Ile Cys Asp Leu Pro Glu Tyr Cys Asp
  65                  70                  75                  80
 Gly Lys Lys Glu Glu Cys Pro Asn Asp Ile Tyr Ile Gln Asp Gly Thr
                  85                  90                  95    
 Pro Cys Ser Ala Val Ser Val Cys Ile Arg Gly Asn Cys Ser Asp Arg
             100                 105                 110        
 Asp Met Gln Cys Gln Ala Leu Phe Gly Tyr Gln Val Lys Asp Gly Ser
         115                 120                 125            
 Pro Ala Cys Tyr Arg Lys Leu Asn Arg Ile Gly Asn Arg Phe Gly Thr
     130                 135                 140                





      <210> 2695
      <211> 440
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(440)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2695
 Thr Met Asn Ser Glu Asp Thr Leu Arg Gln Asn Leu Leu Met Gly Tyr
   1               5                  10                  15    
 Arg Gln His Gln Ala Ile Leu Thr Ala His Ser Thr Gly Pro Arg Arg
              20                  25                  30        
 Pro Ala His Gln Ser Ser Ala Glu Gly Ser Leu Val Pro Cys Ser Gly
          35                  40                  45            
 Asn Pro Val Pro Pro Lys Gly Xaa Leu Trp Ala Arg Gln Gly Pro Ala
      50                  55                  60                
 Glu Val Ser Gly Ala Gly Lys Ile Pro Ala Ser Pro Lys Thr Gly Phe
  65                  70                  75                  80
 Pro Phe Leu Phe Leu Ser Ser His Trp Lys Leu Glu Lys Gly Tyr Ser
                  85                  90                  95    
 Pro Cys Ala Gln Ala Gly Cys Ser Lys Gly Gln Gly Leu Ser Pro Gln
             100                 105                 110        
 Pro Tyr Leu Lys Val Leu Ile Ile Leu Gly Tyr Gln Ala Xaa Lys Gly
         115                 120                 125            
 Ser Xaa Phe Phe Gly Pro Ser Pro Pro Ser Arg Lys Val Phe Pro Ser
     130                 135                 140                
 Met Gly Thr Gly Pro Gln Arg Arg Lys Phe Ser Xaa Pro Arg Phe Pro
 145                 150                 155                 160
 Glu Gly Leu Asn Xaa Pro Asp Cys Gly Pro Gly Thr Glu Pro Pro Leu
                 165                 170                 175    
 Gly Cys Gly Cys Arg Gly Leu Ser Xaa Val Pro Arg Ser Gly Arg Glu
             180                 185                 190        
 Lys Arg Ala Met Ala Asp Pro Xaa Ser Gln Leu Gly Gly Ser Gln Leu
         195                 200                 205            
 Gly Gly Asp Phe Ser Xaa Gly Pro Glu Ala Gly Arg Leu Xaa Val Gly
     210                 215                 220                
 Ala Gln Gln Gly Pro Pro Gly Val Arg Asn Arg His Xaa Ser Pro Leu
 225                 230                 235                 240
 Leu Thr Ser Ser Xaa Arg Pro Lys Ala Arg Ser Pro Asp Glu Ser Arg
                 245                 250                 255    
 Gly Lys Pro Gln Ser Pro Leu Pro Met Met Ser Leu Leu Pro Arg Gly
             260                 265                 270        
 Gly Pro Ser Gly Pro His Leu Gly Pro Pro Leu Glu His Leu Pro Pro
         275                 280                 285            
 Ala Pro Ser Thr Pro Leu Gln Asn Pro Gly Pro Gln Ser Met Val Gly
     290                 295                 300                
 Pro His Ser Asp Phe Tyr Pro Leu Pro Val Ser Pro Trp Gly Ser Arg
 305                 310                 315                 320
 Arg Leu Gln Pro Thr Gln Leu Cys Leu Pro Asp Ser Lys Leu Pro Gly
                 325                 330                 335    
 Ala Ser Pro Pro Gly Ser Ala Lys Met Ala Ala Gly Gln Val Arg Trp
             340                 345                 350        
 Asn Gly Asn Val Ala Arg Pro Thr Pro Pro Gly Asn Xaa Pro Pro Ser
         355                 360                 365            
 Ser Pro Pro Gly Ala Asp Pro Leu Leu Ser Gln Leu Asp Pro Leu Arg
     370                 375                 380                
 Pro Leu Lys Trp Leu Pro Ser Leu Gln Phe Phe Pro Lys Gly Cys Gly
 385                 390                 395                 400
 Leu Gly Cys Leu Cys Pro Gly Pro Pro Ala Ser Glu Arg Ser Val Leu
                 405                 410                 415    
 Ser Pro Ala Pro Gly Pro Gly Leu Val Gly Val Leu Gly Glu Gln Gly
             420                 425                 430        
 Val Ala Arg Thr Pro Gly Gly Arg
         435                 440



      <210> 2696
      <211> 151
      <212> PRT
      <213> Homo sapiens


      <400> 2696
 Ser Gly His Gly Ser Ser Ser Gly Thr Lys Ser Ser Lys Lys Lys Asn
   1               5                  10                  15    
 Gln Asn Ile Gly Tyr Lys Leu Gly His Arg Arg Ala Leu Phe Glu Lys
              20                  25                  30        
 Arg Lys Arg Leu Ser Asp Tyr Ala Leu Ile Phe Gly Met Phe Gly Ile
          35                  40                  45            
 Val Val Met Val Ile Glu Thr Glu Leu Ser Trp Gly Ala Tyr Asp Lys
      50                  55                  60                
 Ala Ser Leu Tyr Ser Leu Ala Leu Lys Cys Leu Ile Ser Leu Ser Thr
  65                  70                  75                  80
 Ile Ile Leu Leu Gly Leu Ile Ile Val Tyr His Ala Arg Glu Ile Gln
                  85                  90                  95    
 Leu Phe Met Val Asp Asn Gly Ala Asp Asp Trp Arg Ile Ala Met Thr
             100                 105                 110        
 Tyr Glu Arg Ile Phe Phe Ile Cys Leu Glu Ile Leu Val Cys Ala Ile
         115                 120                 125            
 His Pro Ile Pro Gly Asn Tyr Thr Phe Thr Trp Thr Ala Arg Leu Ala
     130                 135                 140                
 Phe Ser Tyr Ala Pro Ser Thr
 145                 150    



      <210> 2697
      <211> 270
      <212> PRT
      <213> Homo sapiens


      <400> 2697
 Gly Arg Thr Ser Ser Gly Lys Ala Gly Met Trp Lys Pro Gly Ala Glu
   1               5                  10                  15    
 Ser Trp Pro Leu His Thr Gly Ala Ala Gln Val Met Trp Phe Glu Lys
              20                  25                  30        
 Leu Tyr Ala Gly Leu Gln Cys Val Glu Lys Tyr Leu Ile Tyr Pro Ala
          35                  40                  45            
 Val Val Leu Asn Ala Leu Thr Val Asp Ala His Thr Val Val Ser His
      50                  55                  60                
 Pro Asp Lys Tyr Cys Phe Tyr Cys Arg Ala Leu Leu Met Thr Val Ala
  65                  70                  75                  80
 Gly Leu Lys Leu Leu Arg Ser Ala Phe Cys Cys Pro Pro Gln Gln Tyr
                  85                  90                  95    
 Leu Thr Leu Ala Phe Thr Val Leu Leu Phe His Phe Asp Tyr Pro Arg
             100                 105                 110        
 Leu Ser Gln Gly Phe Leu Leu Asp Tyr Phe Leu Met Ser Leu Leu Cys
         115                 120                 125            
 Ser Lys Leu Trp Asp Leu Leu Tyr Lys Leu Arg Phe Val Leu Thr Tyr
     130                 135                 140                
 Ile Ala Pro Trp Gln Ile Thr Trp Gly Ser Ala Phe His Ala Phe Ala
 145                 150                 155                 160
 Gln Pro Phe Ala Val Pro His Ser Ala Met Leu Phe Val Gln Ala Leu
                 165                 170                 175    
 Leu Ser Gly Leu Phe Ser Thr Pro Leu Asn Pro Leu Leu Gly Ser Ala
             180                 185                 190        
 Val Phe Ile Met Ser Tyr Ala Arg Pro Leu Lys Phe Trp Glu Arg Asp
         195                 200                 205            
 Tyr Asn Thr Lys Arg Val Asp His Ser Asn Thr Arg Leu Val Thr Gln
     210                 215                 220                
 Leu Asp Arg Asn Pro Gly Ala Asp Asp Asn Asn Leu Asn Ser Ile Phe
 225                 230                 235                 240
 Tyr Glu His Leu Thr Arg Ser Leu Gln His Thr Leu Cys Gly Asp Leu
                 245                 250                 255    
 Val Leu Gly Arg Trp Gly Asn Tyr Gly Pro Gly Asp Cys Phe
             260                 265                 270



      <210> 2698
      <211> 244
      <212> PRT
      <213> Homo sapiens


      <400> 2698
 Met Ala Cys Tyr Leu Leu Val Ala Asn Ile Leu Leu Val Asn Leu Leu
   1               5                  10                  15    
 Ile Ala Val Phe Asn Asn Thr Phe Phe Glu Val Lys Ser Ile Ser Asn
              20                  25                  30        
 Gln Val Trp Lys Phe Gln Arg Tyr Gln Leu Ile Met Thr Phe His Glu
          35                  40                  45            
 Arg Pro Val Leu Pro Pro Pro Leu Ile Ile Phe Ser His Met Thr Met
      50                  55                  60                
 Ile Phe Gln His Leu Cys Cys Arg Trp Arg Lys His Glu Ser Asp Pro
  65                  70                  75                  80
 Asp Glu Arg Asp Tyr Gly Leu Lys Leu Phe Ile Thr Asp Asp Glu Leu
                  85                  90                  95    
 Lys Lys Val His Asp Phe Glu Glu Gln Cys Ile Glu Glu Tyr Phe Arg
             100                 105                 110        
 Glu Lys Asp Asp Arg Phe Asn Ser Ser Asn Asp Glu Arg Ile Arg Val
         115                 120                 125            
 Thr Ser Glu Arg Val Glu Asn Met Ser Met Arg Leu Glu Glu Val Asn
     130                 135                 140                
 Glu Arg Glu His Ser Met Lys Ala Ser Leu Gln Thr Val Asp Ile Arg
 145                 150                 155                 160
 Leu Ala Gln Leu Glu Asp Leu Ile Gly Arg Met Ala Thr Ala Leu Glu
                 165                 170                 175    
 Arg Leu Thr Gly Leu Glu Arg Ala Glu Ser Asn Lys Ile Arg Ser Arg
             180                 185                 190        
 Thr Ser Ser Asp Cys Thr Asp Ala Arg Leu His Trp Pro Val Arg Ala
         195                 200                 205            
 Ala Leu Thr Ser Gln Glu Arg Glu His Leu Ser Ala Pro Lys Arg Gly
     210                 215                 220                
 Leu Glu Pro Trp Gln Asn Ile Leu Phe Ile Gln Tyr Lys Pro Ala Ala
 225                 230                 235                 240
 Ser Ser Ser Thr
                



      <210> 2699
      <211> 183
      <212> PRT
      <213> Homo sapiens


      <400> 2699
 Lys Ala Ser Val Ile Val His Ser Asp Val Lys Pro Phe Lys Cys Lys
   1               5                  10                  15    
 Leu Cys Gly Lys Glu Phe Asn Arg Met His Asn Leu Met Gly His Met
              20                  25                  30        
 His Leu His Ser Tyr Ser Lys Pro Phe Lys Cys Leu Tyr Cys Pro Ser
          35                  40                  45            
 Lys Phe Thr Leu Lys Gly Asn Leu Thr Arg His Met Lys Val Lys His
      50                  55                  60                
 Gly Val Met Glu Arg Gly Leu His Ser Gln Gly Leu Gly Arg Gly Arg
  65                  70                  75                  80
 Ile Ala Leu Ala Gln Thr Asp Gly Val Leu Arg Ser Leu Glu Gln Glu
                  85                  90                  95    
 Glu Pro Phe Asp Leu Ser Gln Lys Arg Arg Ala Lys Val Pro Val Phe
             100                 105                 110        
 Gln Ser Asp Gly Glu Ser Ala Gln Gly Ser His Cys His Glu Glu Glu
         115                 120                 125            
 Glu Glu Asp Asn Cys Tyr Glu Val Glu Pro Tyr Ser Pro Gly Leu Ala
     130                 135                 140                
 Pro Gln Ser Gln Gln Leu Cys Thr Pro Glu Asp Leu Ser Thr Lys Ser
 145                 150                 155                 160
 Glu His Ala Pro Glu Val Leu Glu Glu Ala Cys Lys Glu Glu Lys Glu
                 165                 170                 175    
 Asp Ala Ser Lys Gly Glu Trp
             180            



      <210> 2700
      <211> 198
      <212> PRT
      <213> Homo sapiens


      <400> 2700
 Met Thr Glu Glu Glu Glu Trp Lys Pro Met Asp Pro Ser Lys Met Arg
   1               5                  10                  15    
 Cys Ser Phe Phe Gln Asn Gly Lys Glu Ser Glu Lys Glu Lys Val Pro
              20                  25                  30        
 Thr Arg Ser Leu Leu Ala Gln Val Ile Ile Pro Leu Val Asn Tyr Arg
          35                  40                  45            
 Gly Asp Gly Ser Asp Ala Thr Leu Gln Asn Ala Asp Pro Phe Val Gly
      50                  55                  60                
 Lys Ala Gly Leu Gly Phe Val Asp Asp Ser Pro Leu Lys Glu Val Arg
  65                  70                  75                  80
 Cys Gln Arg Gly Leu Met Asp Asn Val His Lys Ser Val Cys Glu Lys
                  85                  90                  95    
 Thr Lys Lys Gly Glu Ala Val Pro Ala Leu Cys Ile Leu Ile Leu Asp
             100                 105                 110        
 Asn Pro Ser Ser Cys Tyr Gln Pro Phe Leu Ala Tyr Pro Arg Tyr Val
         115                 120                 125            
 Lys Pro Ser Ser Glu Ile Pro Ser Ile Leu Pro Trp Lys Glu Asn Ile
     130                 135                 140                
 Glu Leu Gly Lys Gln Ala Thr Asn Asn Ser Phe Thr Glu Tyr Met Leu
 145                 150                 155                 160
 Asn Cys Ala Gly Leu Asp Pro Cys His Ser Met Cys Gly Ser Arg Thr
                 165                 170                 175    
 Lys Ile Ile Ile Ile Thr Cys Glu Leu Ala Arg Asn Ala Glu Ser Gln
             180                 185                 190        
 Ala Pro Pro His Thr Tyr
         195            



      <210> 2701
      <211> 33
      <212> PRT
      <213> Homo sapiens


      <400> 2701
 Gly Gln Ala Arg Trp Leu Met Ser Val Ile Pro Ala Leu Trp Lys Ala
   1               5                  10                  15    
 Glu Ala Gly Gly Pro Leu Glu Pro Arg Ser Ser Arg Pro Ala Trp Ala
              20                  25                  30        
 Thr
    



      <210> 2702
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2702
 Ser Glu Gln Glu Pro Leu Leu Gly Asp Thr Pro Gly Ser Arg Glu Trp
   1               5                  10                  15    
 Asp Ile Leu Glu Thr Glu Glu His Tyr Lys Ser Arg Trp Arg Ser Ile
              20                  25                  30        
 Arg Ile Leu Tyr Leu Thr Met Phe Leu Ser Ser Val Gly Phe Ser Val
          35                  40                  45            
 Val Met Met Ser Ile Trp Pro Tyr Leu Gln Lys Ile Asp Pro Thr Ala
      50                  55                  60                
 Asp Thr Ser Phe Leu Gly Trp Val Ile Ala Ser Tyr Ser Leu Gly Gln
  65                  70                  75                  80
 Met Val Ala Ser Pro Ile Phe Gly Leu Trp Ser Asn Tyr Arg Pro Arg
                  85                  90                  95    
 Lys Glu Pro Leu Ile Val Ser Ile Leu Ile Ser Val Ala Ala Asn Cys
             100                 105                 110        
 Leu Tyr Ala Tyr Leu His Ile Pro Ala Ser His Asn Lys Tyr Tyr Met
         115                 120                 125            
 Leu Val Ala Arg Gly Leu Leu Gly Ile Gly
     130                 135            



      <210> 2703
      <211> 106
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(106)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2703
 Asp Ser Lys Ala Ala Gln Asp Leu Glu Lys Leu His Gly Val Asn Gly
   1               5                  10                  15    
 Met Ser Val Asp Glu Lys Pro Asp Ser Pro Met Tyr Val Tyr Glu Ser
              20                  25                  30        
 Thr Val His Cys Thr Asn Ile Leu Leu Gly Leu Asn Asp Gln Arg Lys
          35                  40                  45            
 Lys Asp Ile Leu Cys Asp Val Thr Leu Ile Val Glu Arg Lys Glu Phe
      50                  55                  60                
 Arg Ala His Arg Ala Val Leu Ala Ala Cys Ser Glu Tyr Phe Trp Gln
  65                  70                  75                  80
 Ala Leu Val Gly Gln Thr Lys Asn Asp Leu Val Val Ser Leu Pro Glu
                  85                  90                  95    
 Glu Val Gln Xaa Phe Gly Leu Cys Asp Cys
             100                 105    



      <210> 2704
      <211> 108
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(108)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2704
 Arg Trp Arg Gln Arg Trp Phe Trp Cys Leu His Cys Leu Val Leu Phe
   1               5                  10                  15    
 Arg Ile Thr Pro Arg Thr Phe Ala Leu Ser Gln Cys Arg Pro Trp Asp
              20                  25                  30        
 Asp Ser Arg Ser Gln Asp Thr Ser Met Ser His Ser Ile Gln Trp Asn
          35                  40                  45            
 Arg Met Tyr Cys Asn Cys Ser Met Gln Asp Glu Gln Glu Ala Asp Glu
      50                  55                  60                
 Ala Asn Gly Lys Gly Pro Ala Gln Val Gly Asp Arg Gln Ala Trp Ala
  65                  70                  75                  80
 Gly Arg Cys Arg Ser His Arg Arg Glu Gly Thr Ile Pro Gly Asn Pro
                  85                  90                  95    
 His Pro Arg Ala Ser Xaa Arg Ala Gly Trp Gln Arg
             100                 105            



      <210> 2705
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 2705
 Met Leu Leu His Val Gly Thr Thr Ala His Val Ala Val Glu His Leu
   1               5                  10                  15    
 Ile Gly Gly Val Gln Asp Asp Glu Asp Leu Glu Met Thr Ile Gly Cys
              20                  25                  30        
 His Gly Glu Glu Met Ile Gly Asp Leu Asp Lys Asn Ser Phe Gly Ala
          35                  40                  45            
 Gly Gly Leu Cys Ile Gly Glu Arg Val Gly Gly Pro Gly Cys Cys Glu
      50                  55                  60                
 Val Leu Ile Arg Met Thr Pro Thr Glu Asp Val Gly Glu Glu Arg Ser
  65                  70                  75                  80
 Asp Met Lys Gly Ile Gln Leu Ser Met Gln Glu Arg Thr Arg Cys Arg
                  85                  90                  95    
 Gln Phe Pro Glu Gly Arg Arg His Gln Leu Gly His Leu Leu Gln Gly
             100                 105                 110        
 Gly Leu Gly Arg Gly Glu Ala Trp Lys Tyr His Gln Ile Trp Glu Glu
         115                 120                 125            
 Gly His Trp Leu Leu Arg Glu Gln
     130                 135    



      <210> 2706
      <211> 44
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(44)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2706
 Arg Gly Met Gly Arg Thr Tyr Arg Gly Arg His Thr Asp Ser Arg Lys
   1               5                  10                  15    
 Ser Asp Arg Xaa Xaa Gly Gly Arg Arg Gln Lys Thr Gln Lys Pro Met
              20                  25                  30        
 Ser Cys Ile Thr Val Gln Arg Lys His Gly Thr Ser
          35                  40                



      <210> 2707
      <211> 458
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(458)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2707
 Gly Thr Ser Gly Val Gln Gln Glu Ile Ser Arg Leu Thr Asn Glu Asn
   1               5                  10                  15    
 Leu Asp Leu Lys Glu Leu Val Glu Lys Leu Glu Lys Asn Glu Arg Lys
              20                  25                  30        
 Leu Lys Lys Gln Leu Lys Ile Tyr Met Lys Lys Ala Gln Asp Leu Glu
          35                  40                  45            
 Ala Ala Gln Ala Leu Ala Gln Ser Glu Arg Lys Arg His Glu Leu Asn
      50                  55                  60                
 Arg Gln Val Thr Val Gln Arg Lys Glu Lys Asp Phe Gln Gly Met Leu
  65                  70                  75                  80
 Glu Tyr His Lys Glu Asp Glu Ala Leu Leu Ile Arg Asn Leu Val Thr
                  85                  90                  95    
 Asp Leu Lys Pro Gln Met Leu Ser Gly Thr Val Pro Cys Leu Pro Ala
             100                 105                 110        
 Tyr Ile Leu Tyr Met Cys Ile Arg His Ala Asp Tyr Thr Asn Asp Asp
         115                 120                 125            
 Leu Lys Val His Ser Leu Leu Thr Ser Thr Ile Asn Gly Ile Lys Lys
     130                 135                 140                
 Val Leu Lys Lys His Asn Asp Asp Phe Glu Met Thr Ser Phe Trp Leu
 145                 150                 155                 160
 Ser Asn Thr Cys Arg Leu Leu His Cys Leu Lys Gln Tyr Ser Gly Asp
                 165                 170                 175    
 Glu Gly Phe Met Thr Gln Asn Thr Ala Lys Gln Asn Glu His Cys Leu
             180                 185                 190        
 Lys Asn Phe Asp Leu Thr Glu Tyr Arg Gln Val Leu Ser Asp Leu Ser
         195                 200                 205            
 Ile Gln Ile Tyr Gln Gln Leu Ile Lys Ile Ala Glu Gly Val Leu Gln
     210                 215                 220                
 Pro Met Ile Val Ser Ala Met Leu Glu Asn Xaa Ser Ile Gln Gly Leu
 225                 230                 235                 240
 Ser Gly Val Lys Pro Thr Gly Ser Gln Lys His Ser Ser Ser Met Ala
                 245                 250                 255    
 Asp Glu Asp Asn Ser Tyr Arg Leu Glu Ala Ile Ile Arg Gln Met Asn
             260                 265                 270        
 Ala Phe His Thr Val Met Cys Asp Gln Gly Leu Asp Pro Glu Ile Ile
         275                 280                 285            
 Leu Gln Val Phe Lys Gln Leu Phe Tyr Met Ile Asn Ala Val Thr Leu
     290                 295                 300                
 Asn Asp Leu Leu Leu Arg Lys Asp Val Cys Ser Trp Ser Thr Gly Met
 305                 310                 315                 320
 Gln Leu Arg Tyr Asn Ile Ser Gln Leu Glu Glu Trp Leu Arg Gly Arg
                 325                 330                 335    
 Asn Leu His Gln Ser Gly Ala Val Gln Thr Met Glu Pro Leu Ile Gln
             340                 345                 350        
 Ala Ala Gln Leu Leu Gln Leu Lys Lys Lys Thr Gln Glu Asp Ala Glu
         355                 360                 365            
 Ala Ile Cys Ser Leu Cys Thr Ser Leu Ser Thr Gln Gln Ile Val Lys
     370                 375                 380                
 Ile Leu Asn Leu Tyr Thr Pro Leu Asn Glu Phe Glu Glu Arg Val Thr
 385                 390                 395                 400
 Val Ala Phe Ile Arg Thr Ile Gln Ala Gln Leu Gln Glu Arg Asn Asp
                 405                 410                 415    
 Pro Gln Gln Leu Leu Leu Asp Ala Lys His Met Phe Pro Val Leu Phe
             420                 425                 430        
 Pro Phe Asn Pro Ser Ser Leu Thr Met Asp Ser Ile His Ile Pro Ala
         435                 440                 445            
 Cys Leu Asn Leu Glu Phe Leu Asn Glu Val
     450                 455            



      <210> 2708
      <211> 156
      <212> PRT
      <213> Homo sapiens


      <400> 2708
 Met Gln Gly Leu Val Asn Tyr Gln Ile Ser Ile Lys Cys Ser Asn Gln
   1               5                  10                  15    
 Phe Lys Leu Glu Val Cys Leu Leu Asn Ala Glu Asn Lys Val Val Asp
              20                  25                  30        
 Asn Gln Ala Gly Thr Gln Gly Gln Leu Lys Val Leu Gly Ala Asn Leu
          35                  40                  45            
 Trp Trp Pro Tyr Leu Met His Glu His Pro Ala Tyr Leu Tyr Ser Trp
      50                  55                  60                
 Glu Val Arg Leu Thr Ala Gln Lys Ser Leu Gly Pro Leu Thr Ser Thr
  65                  70                  75                  80
 His Ser Leu Trp Gly Ser Ala Leu Cys Pro Ser Pro Arg Ala Ser Gly
                  85                  90                  95    
 Met Val Ile Ala His Thr Lys Ala Leu Asp Pro Ser Gln Pro Val Thr
             100                 105                 110        
 Phe Val Thr Asn Val Thr Tyr Ala Ala Asp Lys Gly Pro Leu Trp Glu
         115                 120                 125            
 Val Ala Ala Pro Ser Ser Ser Gln Arg Ala Ser Ser Gly Val Thr Glu
     130                 135                 140                
 Leu Thr Arg Val Thr Pro Val Asp Leu Gln Ile Glu
 145                 150                 155    



      <210> 2709
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 2709
 Thr Ser Asn Pro Lys Asn Lys Val Gly Leu Leu Asp Leu Glu Leu Asn
   1               5                  10                  15    
 Arg Leu Thr Lys Ala Leu Phe Met Ala Leu Val Ala His Ser Ile Val
              20                  25                  30        
 Met Val Thr Ile Gln Gly Phe Val Gly Pro Trp Tyr Arg Asn Leu Phe
          35                  40                  45            
 Arg Phe Leu Pro Leu Phe Ser Tyr Ile Ile Thr Ile Ser Leu Arg Val
      50                  55                  60                
 Asn Leu Asp Met Gly Lys Ala Val Tyr Gly Trp Met Met Met Lys Asp
  65                  70                  75                  80
 Glu Asn Ile Pro Gly Thr Val Val Arg Thr Ser Thr Ile Pro Glu Glu
                  85                  90                  95    
 Leu Gly Arg Val Val Tyr Leu Leu Thr Asp Lys Thr Gly Pro Leu Thr
             100                 105                 110        
 Gln Asn Glu Met Ile Phe Lys Arg Leu His Leu Gly Thr Val Ser Tyr
         115                 120                 125            
 Gly Ala Asp Thr Met Tyr Glu Ile His Thr Lys
     130                 135                



      <210> 2710
      <211> 190
      <212> PRT
      <213> Homo sapiens


      <400> 2710
 Met Ser Ala Ala Cys Gly Gln Asn Tyr Thr Leu Ala Leu Met Glu Met
   1               5                  10                  15    
 Gly Ser Val Phe Ala Phe Gly Glu Asn Lys Met Gly Gln Leu Gly Leu
              20                  25                  30        
 Gly Asn Leu Thr Asp Thr Ile Pro Ser Pro Ala Gln Ile Ile Tyr Asn
          35                  40                  45            
 Gly Gln Pro Ile Thr Lys Met Ala Phe Gly Ala Glu Phe Ser Met Ile
      50                  55                  60                
 Met Asp Cys Lys Gly Asn Leu Tyr Ser Phe Gly Cys His Glu Tyr Gly
  65                  70                  75                  80
 Gln Leu Gly His Asn Ser Asp Gly Lys Phe Ile Ala Arg Ala Arg Arg
                  85                  90                  95    
 Thr Asp Gly Tyr Gly Arg Leu Gly His Ala Glu Gln Asp Glu Met Val
             100                 105                 110        
 Pro His Leu Val Lys Leu Phe Asp Phe Pro Gly His Arg Val Ser Gln
         115                 120                 125            
 Ile Tyr Thr Gly Tyr Thr Cys Ser Phe Ala Ile Ser Glu Val Gly Gly
     130                 135                 140                
 Leu Phe Phe Gln Gly Ala Thr Asn Thr Ser Arg Glu Ser Thr Thr Tyr
 145                 150                 155                 160
 Pro Lys Ala Val Gln Asp Leu Cys Gly Trp Ile Ile Gln Ser Leu Ala
                 165                 170                 175    
 Cys Gly Lys Ser Ser Ile Ile Val Ala Thr Glu Arg Ala Pro
             180                 185                 190



      <210> 2711
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 2711
 Ala Trp Glu Gly Ala His Val Phe Thr Thr Ser Pro Ser Ser Cys His
   1               5                  10                  15    
 Ser Trp Val Arg Asp Tyr Ala Arg Val Gly Leu Pro Pro Leu Pro Leu
              20                  25                  30        
 Pro Cys Pro Gln Arg Ala Leu Leu Gly Leu Trp Glu Val Trp Lys Gly
          35                  40                  45            
 Ala Tyr Ser Pro Ala Ile
      50                



      <210> 2712
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 2712
 Met Ala Leu Arg His Leu Ala Leu Leu Ala Gly Leu Leu Val Gly Val
   1               5                  10                  15    
 Ala Ser Lys Ser Met Glu Asn Thr Asp Thr Asp Val Pro Ala Pro Glu
              20                  25                  30        
 Val Leu Thr Arg Ser Thr Ala Gly Val Arg Gly Ala Cys Ala Ser Gln
          35                  40                  45            
 Arg Gly Ala Leu Arg Cys Leu Leu Gly Pro
      50                  55            



      <210> 2713
      <211> 168
      <212> PRT
      <213> Homo sapiens


      <400> 2713
 Met Glu Arg Gly Pro Val Thr Cys Thr Gln Ala Gln Thr Val Arg Gly
   1               5                  10                  15    
 Arg Thr Gly His Arg Arg Arg Phe Gly Pro Gly Ala His Gly Leu Arg
              20                  25                  30        
 Glu Glu Pro Glu Phe Val Thr Ala Arg Ala Gly Glu Ser Val Val Leu
          35                  40                  45            
 Arg Cys Asp Val Ile His Pro Val Thr Gly Gln Pro Pro Pro Tyr Val
      50                  55                  60                
 Val Glu Trp Phe Lys Phe Gly Val Pro Ile Pro Ile Phe Ile Lys Phe
  65                  70                  75                  80
 Gly Tyr Tyr Pro Pro His Val Asp Pro Glu Tyr Ala Glu Gln Ser Cys
                  85                  90                  95    
 Phe Gln Ala Pro Ser Phe Pro Ser Pro Ser Pro Ala Glu Glu Leu Arg
             100                 105                 110        
 Val Val Ser Ala Arg His Gly Leu Cys Gln Ala Leu Asp Ala Ser Trp
         115                 120                 125            
 Phe Cys Thr Gly Val Gln Arg Gln Pro Trp Thr Gln Pro Pro Thr Gly
     130                 135                 140                
 Tyr His Leu Ala Gln Arg Ala Gly Asp Leu Tyr Pro Val Gly Phe Pro
 145                 150                 155                 160
 Lys Glu Thr Tyr Phe Glu Lys Val
                 165            



      <210> 2714
      <211> 87
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(87)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2714
 Lys Gln Cys Gln Arg Arg Cys Leu Glu Thr Glu Val Trp Lys Leu Ser
   1               5                  10                  15    
 Lys Leu Gln Ile Ser Thr Lys Ala Ser Asn Arg Gln Asp Arg Ser Thr
              20                  25                  30        
 Phe Ser Ala Pro Pro Arg Lys Ser Gln Leu Met Trp Xaa Thr Ser Leu
          35                  40                  45            
 Leu Ser Tyr Phe Gln Lys Leu Pro Gln Ser Pro Gln Pro Ser Ala Thr
      50                  55                  60                
 Thr Ala Leu Ile Ser Gln Gln Pro Ser Thr Leu Asn Pro Gln Pro Trp
  65                  70                  75                  80
 Pro Gly Ser Cys Pro Gly Gly
                  85        



      <210> 2715
      <211> 295
      <212> PRT
      <213> Homo sapiens


      <400> 2715
 Met Arg Ile Arg Arg Trp Ser Leu Met Phe Asp Ser Val Trp Pro Met
   1               5                  10                  15    
 Cys Ala Phe Tyr Ser Trp Ala Lys Ala Ser Arg Thr Phe Leu Lys Ala
              20                  25                  30        
 Asp Gly Leu Pro Arg Arg Lys Gln Trp Val Leu Val Glu Ala Leu Ala
          35                  40                  45            
 Gly Gly Gly Val Leu Gly Val Lys Gln Ile Thr Ile Gln Val Leu Phe
      50                  55                  60                
 Glu Val Leu Leu Arg Arg Gly Lys Glu Ser Glu Thr Tyr Thr Lys Met
  65                  70                  75                  80
 Tyr Arg Arg Leu Gly Pro Glu Arg Cys Arg Arg Ser Lys Tyr Ala Gly
                  85                  90                  95    
 Val Glu Arg Ile Val Asp Lys Arg Lys Asn Lys Lys Gly Lys Trp Glu
             100                 105                 110        
 Tyr Leu Ile Arg Trp Lys Gly Tyr Gly Ser Thr Glu Asp Thr Trp Glu
         115                 120                 125            
 Pro Glu His His Leu Leu His Cys Glu Glu Phe Ile Asp Glu Phe Asn
     130                 135                 140                
 Gly Leu His Met Ser Lys Asp Lys Arg Ile Lys Ser Gly Lys Gln Ser
 145                 150                 155                 160
 Ser Thr Ser Lys Leu Leu Arg Asp Ser Arg Gly Pro Ser Val Glu Lys
                 165                 170                 175    
 Leu Ser His Arg Pro Ser Asp Pro Gly Lys Ser Lys Gly Thr Ser His
             180                 185                 190        
 Lys Arg Lys Arg Ile Asn Pro Pro Leu Ala Lys Pro Lys Lys Gly Tyr
         195                 200                 205            
 Ser Gly Lys Pro Ser Ser Gly Gly Asp Arg Ala Thr Lys Thr Val Ser
     210                 215                 220                
 Tyr Arg Thr Thr Pro Ser Gly Leu Gln Ile Met Pro Leu Lys Lys Ser
 225                 230                 235                 240
 Gln Asn Gly Met Glu Asn Gly Asp Ala Gly Ser Glu Lys Asp Glu Arg
                 245                 250                 255    
 His Phe Gly Asn Gly Ser His Gln Pro Gly Leu Asp Leu Asn Asp His
             260                 265                 270        
 Val Gly Glu Gln Asp Met Gly Glu Cys Asp Val Asn His Ala Thr Leu
         275                 280                 285            
 Ala Glu Asn Gly Leu Gly Leu
     290                 295



      <210> 2716
      <211> 971
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(971)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2716
 Arg Thr Arg Ser Leu Thr Arg Lys Ala Met Ala Glu His Ala Pro Arg
   1               5                  10                  15    
 Arg Cys Cys Leu Gly Trp Asp Phe Ser Thr Gln Gln Val Lys Val Val
              20                  25                  30        
 Ala Val Asp Ala Glu Leu Asn Val Phe Tyr Glu Glu Ser Val His Phe
          35                  40                  45            
 Asp Arg Asp Leu Pro Glu Phe Gly His Val Leu Asp Val His Gly Val
      50                  55                  60                
 His Val His Lys Asp Gly Leu Thr Val Thr Ser Pro Val Leu Met Trp
  65                  70                  75                  80
 Val Gln Ala Leu Asp Ile Ile Leu Glu Lys Met Lys Ala Ser Gly Phe
                  85                  90                  95    
 Glu Phe Ser Gln Val Leu Ala Leu Ser Gly Ala Gly Gln Gln His Gly
             100                 105                 110        
 Ser Ile Tyr Trp Lys Ala Gly Ala Gln Gln Ala Leu Thr Ser Leu Ser
         115                 120                 125            
 Pro Asp Leu Arg Leu His Gln Gln Leu Gln Asp Cys Phe Ser Ile Ser
     130                 135                 140                
 Asp Cys Pro Val Trp Met Asp Ser Ser Thr Thr Ala Gln Cys Arg Gln
 145                 150                 155                 160
 Leu Glu Ala Ala Val Gly Gly Ala Gln Ala Leu Ser Cys Leu Thr Gly
                 165                 170                 175    
 Ser Arg Ala Tyr Glu Phe Asn Leu Val Cys Asp Arg Lys His Leu Lys
             180                 185                 190        
 Asp Thr Thr Gln Ser Val Phe Met Ala Gly Leu Leu Val Gly Thr Leu
         195                 200                 205            
 Met Phe Gly Pro Leu Cys Asp Arg Ile Gly Arg Lys Ala Thr Ile Leu
     210                 215                 220                
 Ala Gln Leu Leu Leu Phe Thr Leu Ile Gly Leu Ala Thr Ala Phe Val
 225                 230                 235                 240
 Pro Ser Phe Glu Leu Tyr Met Ala Leu Arg Phe Ala Gly Leu Leu Pro
                 245                 250                 255    
 Ser Leu Asp Leu Ala Ser Ala Met Ser Pro Tyr Xaa Gln Asn Gly Trp
             260                 265                 270        
 Gly Pro His Gly Gly Arg Arg Pro Trp Ser Trp Pro Ser Ala Thr Ser
         275                 280                 285            
 Pro Ser Gly Arg Trp Cys Leu Arg Asp Ser Pro Thr Val Ser Ala Thr
     290                 295                 300                
 Gly Gly Ser Phe Arg Ser Pro Ala Leu Arg Leu Ala Tyr Cys Ser Ser
 305                 310                 315                 320
 Leu Leu Leu Gly Ser Ala Arg Ile Cys Thr Leu Ala Pro Asp Pro Trp
                 325                 330                 335    
 Glu Asp Gly Arg Gly Asp Thr Thr Asp Pro Glu Asn Gly Leu Gly Gln
             340                 345                 350        
 Xaa Ala Glu Thr Leu Pro Gly Ala His Glu Pro Ala Gly Pro Arg Glu
         355                 360                 365            
 Asp Arg Pro Leu Arg Glu Cys Pro Gly Ser Val Gln Thr Pro Pro Ala
     370                 375                 380                
 Pro Glu Gly Asp Pro Asp Tyr Leu Leu Cys Leu Val Cys Gly Gln Ser
 385                 390                 395                 400
 Gly Val Leu Arg Pro Glu Pro Pro Ser Gly Gly Leu Arg Pro Gly Arg
                 405                 410                 415    
 Leu Ser Asp Ala Ala His Leu Trp Ser Cys Xaa Gly Ala Cys Pro Leu
             420                 425                 430        
 Phe Gln His Leu His Asp Ala Glu Val Trp Pro Gln Val Glu Pro Arg
         435                 440                 445            
 Trp Gly Pro Trp Ser Trp Val Ala Xaa Cys Val Ser Ser Ser Ser Ser
     450                 455                 460                
 Ser Gln Gln Ile Cys Pro Trp Trp Ser Pro Cys Trp Leu Trp Trp Gly
 465                 470                 475                 480
 Lys Trp Pro Gln Leu Leu Pro Leu Pro Ser Pro Met Cys Thr Leu Pro
                 485                 490                 495    
 Ser Phe Ser Pro Pro Ser Ser Gly Arg Gln Ala Trp Gly Trp Trp Ala
             500                 505                 510        
 Ser Ser His Gly Ser Gly Ala Ser Ser His His Leu Xaa Ser Cys Trp
         515                 520                 525            
 Glu Ser Thr Thr Leu Pro Ser Pro Cys Ser Ser Thr Ala Ala Ser Pro
     530                 535                 540                
 Ser Trp Pro Ala Ser Leu Cys Thr Leu Leu Pro Glu Thr His Gly Gln
 545                 550                 555                 560
 Gly Leu Lys Asp Thr Leu Gln Asp Leu Glu Leu Gly Pro His Pro Arg
                 565                 570                 575    
 Ser Pro Lys Ser Val Pro Ser Glu Lys Glu Thr Glu Ala Lys Gly Arg
             580                 585                 590        
 Thr Ser Ser Pro Gly Val Ala Phe Val Ser Leu Gly Thr Ser Asp Thr
         595                 600                 605            
 Leu Phe Leu Trp Leu Gln Glu Pro Met Pro Ala Leu Glu Gly His Ile
     610                 615                 620                
 Phe Cys Asn Pro Val Asp Ser Gln His Tyr Met Ala Leu Leu Cys Phe
 625                 630                 635                 640
 Lys Asn Gly Ser Leu Met Arg Glu Lys Ile Arg Asn Glu Ser Val Ser
                 645                 650                 655    
 Arg Ser Trp Ser Asp Phe Ser Lys Ala Leu Gln Ser Thr Glu Met Gly
             660                 665                 670        
 Asn Gly Gly Asn Leu Gly Phe Tyr Phe Asp Val Met Glu Ile Thr Pro
         675                 680                 685            
 Glu Ile Ile Gly Arg His Arg Phe Asn Thr Glu Asn His Lys Tyr Phe
     690                 695                 700                
 Lys Gly Lys Gly Ala Pro Gly His Pro Met Pro Ser Leu Lys Ala Asn
 705                 710                 715                 720
 Phe Asp Leu Leu Ala Cys Leu Arg Gly Val Gly Ser Ser Thr Leu Leu
                 725                 730                 735    
 Leu Trp Pro Ala Val Leu Gly Ala Gln Thr Arg Gln Ala Gly Val Asn
             740                 745                 750        
 Glu Gly Arg Ser Gln Val Ala Asp Phe Leu Arg Ile Pro Val Thr Gly
         755                 760                 765            
 Cys Pro Glu Gln Arg Arg Asn Pro Pro Ser Pro Pro Ala Pro Leu Gly
     770                 775                 780                
 Thr Gly Gly Pro Ala Glu Glu Arg Leu Gln Phe Pro Gly Val Ala Gly
 785                 790                 795                 800
 Ser Arg Arg Gly Arg Gly Arg Ile Leu Arg Ala Gly Gly Ile Gly Arg
                 805                 810                 815    
 Ala Ser Pro Gly Glu Gly Thr Gly Ala Pro Arg Pro Arg Ala Gly Gln
             820                 825                 830        
 Gly Arg Gly Gly Pro Gly Lys Pro Glu Ser Gly Gly Gly Gly Pro Val
         835                 840                 845            
 Ala Leu Arg Pro Gly Asp Cys Thr Cys Cys Val Leu Lys Ser Gln Pro
     850                 855                 860                
 Arg Gln Gln Arg Arg Gly Ala Cys Ser Ala Met Ala Phe Arg Val Arg
 865                 870                 875                 880
 Leu Arg Val Arg Gln Ser Val Arg Pro Pro Arg Gly Val Ile Val Ala
                 885                 890                 895    
 Ala Leu Gln Arg Pro Glu Thr Gln Gly Pro Ala Pro Ser Ser Ala Arg
             900                 905                 910        
 Pro Asp Cys Gly Pro Glu Ser Arg Gly Gly Leu Ala Leu Trp Arg Arg
         915                 920                 925            
 Leu Arg Gly Tyr Ala Ser Arg Asp Arg Val Leu Cys Asn Arg Arg Cys
     930                 935                 940                
 Pro His Ala Ala Arg Phe Pro Ser Lys Arg Thr Pro Ser Gly Ser Pro
 945                 950                 955                 960
 His Leu His Leu Met Ser Ser Trp Ala Val Pro
                 965                 970    



      <210> 2717
      <211> 315
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(315)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2717
 Leu Arg Ser Asn His Gly Glu Asp Trp Ser Gln Phe Ile Gly Ala Ala
   1               5                  10                  15    
 Gln Arg Glu Thr Thr Val Ser Leu Leu Pro Met Pro His Thr Trp Pro
              20                  25                  30        
 Val Ser Leu Ser Thr Gly Ser Cys Met Thr Arg Gly Thr Pro Ile Leu
          35                  40                  45            
 Pro Phe Ile Asn Asn Pro Gln Leu Gln Val His Phe His Arg Glu Asp
      50                  55                  60                
 Asp Glu His Ser Asp Ile Ala Phe His Phe Xaa Val Tyr Phe Gly His
  65                  70                  75                  80
 Trp Val Ile Met Asn Ser His Glu Cys Gly Ala Trp Lys Cys Glu Glu
                  85                  90                  95    
 Arg Ser Asn Asn Met Pro Ala Glu Asp Gly Arg Val Phe Glu Leu His
             100                 105                 110        
 Ile Ile Val Leu Asp Asn Glu Tyr Gln Ala Met Val Asn Gly Gln Ser
         115                 120                 125            
 Leu Leu His Ser Phe Ala His Arg Leu Leu Pro Gly Ser Val Lys Met
     130                 135                 140                
 Val Gln Val Trp Arg Asp Val Ser Leu Asn Ser Arg Cys Val Ser Ser
 145                 150                 155                 160
 Gly Glu Thr Val Ser Ser Ser Ser Ser Phe Leu Pro Pro Pro Pro Pro
                 165                 170                 175    
 Pro Leu Pro Leu Pro Leu Leu Leu Leu Leu Pro Pro Leu Pro Leu Pro
             180                 185                 190        
 Asp Glu Ala Leu Phe Leu Ser Leu Pro Ser His Ala Leu Pro Ser Gly
         195                 200                 205            
 Arg Cys Gly Val Leu Ser Leu Cys Gly Ser His Tyr Pro Gln Pro Gly
     210                 215                 220                
 Gly Leu Leu Gln Ser Ser Ala Gly Ala Ser Gly Arg Arg Gly Ala Pro
 225                 230                 235                 240
 Gly Val Pro Trp Gln Val Leu Val Leu Leu Thr Pro Arg Gly Leu Gln
                 245                 250                 255    
 Gly Pro Pro Pro Gly Met Arg Gly Arg Val Val His Lys Pro Leu Leu
             260                 265                 270        
 Val Met Glu Leu Gly Glu Gln Pro Phe Ser Phe Pro Ser Val Arg Thr
         275                 280                 285            
 Ala Thr Ser Ser Ala Ser Gly Lys Ala Pro Pro Arg Cys Pro Trp Pro
     290                 295                 300                
 Gly Pro Arg Ala Leu Ser Pro Ser Ser Val Pro
 305                 310                 315



      <210> 2718
      <211> 408
      <212> PRT
      <213> Homo sapiens


      <400> 2718
 Ser Leu Gly Ser Thr Ile Ser Thr Asp Trp Ala Asn His Tyr Leu Ala
   1               5                  10                  15    
 Lys Ser Gly His Lys Arg Leu Ile Arg Asp Leu Gln Gln Asp Val Thr
              20                  25                  30        
 Asp Gly Val Leu Leu Ala Gln Ile Ile Gln Val Val Ala Asn Glu Lys
          35                  40                  45            
 Ile Glu Asp Ile Asn Gly Cys Pro Lys Asn Arg Ser Gln Met Ile Glu
      50                  55                  60                
 Asn Ile Asp Ala Cys Leu Asn Phe Leu Ala Ala Lys Gly Ile Asn Ile
  65                  70                  75                  80
 Gln Gly Leu Ser Ala Glu Glu Ile Lys Asn Gly Asn Leu Lys Ala Ile
                  85                  90                  95    
 Leu Gly Leu Phe Phe Ser Leu Ser Arg Tyr Lys Gln Gln Gln Gln Gln
             100                 105                 110        
 Pro Gln Lys Gln His Leu Ser Ser Pro Leu Pro Pro Ala Val Ser Gln
         115                 120                 125            
 Val Ala Gly Ala Pro Ser Gln Cys Gln Ala Gly Thr Pro Gln Gln Ala
     130                 135                 140                
 Pro Gly Val Pro Val Thr Pro Gln Ala Pro Cys Gln Pro His Gln Pro
 145                 150                 155                 160
 Ala Pro His Gln Gln Ser Lys Ala Gln Ala Glu Met Gln Ser Arg Leu
                 165                 170                 175    
 Pro Gly Pro Thr Ala Arg Val Ser Ala Ala Gly Ser Glu Ala Lys Thr
             180                 185                 190        
 Arg Gly Gly Ser Thr Thr Ala Asn Asn Arg Arg Ser Gln Ser Phe Asn
         195                 200                 205            
 Asn Tyr Asp Lys Ser Lys Pro Val Thr Ser Pro Pro Pro Pro Pro Ser
     210                 215                 220                
 Ser His Glu Lys Glu Pro Leu Ala Ser Ser Ala Ser Ser His Pro Gly
 225                 230                 235                 240
 Met Ser Asp Asn Ala Pro Ala Ser Leu Glu Ser Gly Ser Ser Ser Thr
                 245                 250                 255    
 Pro Thr Asn Cys Ser Thr Tyr Ser Gly Ile Pro His Ser Gly Ala Ala
             260                 265                 270        
 Thr Lys Pro Trp Arg Ser Lys Ser Leu Ser Val Lys His Ser Ala Thr
         275                 280                 285            
 Val Ser Met Leu Ser Val Lys Pro Pro Gly Pro Glu Ala Pro Arg Pro
     290                 295                 300                
 Thr Pro Glu Ala Met Lys Pro Ala Pro Asn Asn Gln Lys Ser Met Leu
 305                 310                 315                 320
 Glu Lys Leu Lys Leu Phe Asn Ser Lys Gly Gly Ser Lys Ala Gly Glu
                 325                 330                 335    
 Gly Pro Gly Ser Arg Asp Thr Ser Cys Glu Arg Leu Glu Thr Leu Pro
             340                 345                 350        
 Ser Phe Glu Glu Ser Glu Glu Leu Glu Ala Ala Ser Arg Met Leu Thr
         355                 360                 365            
 Thr Val Gly Pro Ala Ser Ser Ser Pro Lys Ile Ala Leu Lys Gly Ile
     370                 375                 380                
 Ala Gln Arg Thr Phe Ser Arg Ala Leu Thr Asn Lys Lys Ser Ser Leu
 385                 390                 395                 400
 Lys Gly Asn Glu Lys Gly Lys Glu
                 405            



      <210> 2719
      <211> 213
      <212> PRT
      <213> Homo sapiens


      <400> 2719
 Asn Ala Asn Thr Gln Arg Ala Arg Arg Arg Glu Gly Ala Arg Leu Asp
   1               5                  10                  15    
 Asn Leu Trp Leu Glu Gln Val Ile Ser Val Leu Pro Gly Leu Val Thr
              20                  25                  30        
 Gln Gly Phe Arg Cys His Ser Gly Pro Met Gly Arg Gly Leu Glu Pro
          35                  40                  45            
 His Pro Ile Arg Gly Ala Gly Ala Gly Ser Cys Gln Leu Ser Ile Arg
      50                  55                  60                
 Gly Arg Gly Gly Arg Ile Pro Ala Phe Leu Thr Pro Arg Arg Leu Ala
  65                  70                  75                  80
 Pro Lys Gly Gly Arg Asp Leu Gly Phe Pro Ala Pro Arg Gly Thr Arg
                  85                  90                  95    
 Cys Leu Arg His Ser Phe Cys Arg Ser Ile Ala Arg Thr Val Thr Arg
             100                 105                 110        
 Thr Val Arg Gly Ile Arg Gly Glu Glu Ala Arg Thr Pro Gly Ser Arg
         115                 120                 125            
 Glu Met Asp Ser Val Val Phe Glu Asp Val Asp Val Asn Phe Thr Gln
     130                 135                 140                
 Glu Glu Trp Ala Leu Leu Asp Pro Ser Gln Lys Asn Leu Tyr Arg Asp
 145                 150                 155                 160
 Val Met Gln Glu Thr Phe Arg Asn Leu Ala Ser Val Gly Lys Lys Trp
                 165                 170                 175    
 Lys Asp Gln Lys Ile Glu Asp Glu Tyr Lys Asn Pro Arg Arg Asn Leu
             180                 185                 190        
 Arg Asn Tyr Val Tyr His Phe Ser Leu Lys Lys Trp Ser Trp Ser Leu
         195                 200                 205            
 Tyr Ala Arg Gln Thr
     210            



      <210> 2720
      <211> 224
      <212> PRT
      <213> Homo sapiens


      <400> 2720
 Leu Leu Leu His Ser Leu Phe Pro Val Pro Arg Met Gly Asn Ser Ala
   1               5                  10                  15    
 Ser Asn Ile Val Ser Pro Gln Glu Ala Leu Pro Gly Arg Lys Glu Gln
              20                  25                  30        
 Thr Pro Val Ala Ala Lys His His Val Asn Gly Asn Arg Thr Val Glu
          35                  40                  45            
 Pro Phe Pro Glu Gly Thr Gln Met Ala Val Phe Gly Met Gly Cys Phe
      50                  55                  60                
 Trp Gly Ala Glu Arg Lys Phe Trp Val Leu Lys Gly Val Tyr Ser Thr
  65                  70                  75                  80
 Gln Val Gly Phe Ala Gly Gly Tyr Thr Ser Asn Pro Thr Tyr Lys Glu
                  85                  90                  95    
 Val Cys Ser Glu Lys Thr Gly His Ala Glu Val Val Arg Val Val Tyr
             100                 105                 110        
 Gln Pro Glu His Met Ser Phe Glu Glu Leu Leu Lys Val Phe Trp Glu
         115                 120                 125            
 Asn His Asp Pro Thr Gln Gly Met Arg Gln Gly Asn Asp His Gly Thr
     130                 135                 140                
 Gln Tyr Arg Ser Ala Ile Tyr Pro Thr Ser Ala Lys Gln Met Glu Ala
 145                 150                 155                 160
 Ala Leu Ser Ser Lys Glu Asn Tyr Gln Lys Val Leu Ser Glu His Gly
                 165                 170                 175    
 Phe Gly Pro Ile Thr Thr Asp Ile Arg Glu Gly Gln Thr Phe Tyr Tyr
             180                 185                 190        
 Ala Glu Asp Tyr His Gln Gln Tyr Leu Ser Lys Asn Pro Asn Gly Tyr
         195                 200                 205            
 Cys Gly Leu Gly Gly Thr Gly Val Ser Cys Pro Val Gly Ile Lys Lys
     210                 215                 220                





      <210> 2721
      <211> 808
      <212> PRT
      <213> Homo sapiens


      <400> 2721
 Asn Glu Ile Glu Lys Gln Leu Asn Ala Ile Arg Asp Asn Ile Lys Ile
   1               5                  10                  15    
 Gly Glu Asp Arg Ala Ala Arg Leu Asp Arg Lys Met Glu Glu Gln Gln
              20                  25                  30        
 Val Arg Leu Asn Glu Ala Glu Gln Lys Tyr Lys Asp Ile Gln Asp Lys
          35                  40                  45            
 Leu Glu Lys Ile Ser Glu Glu Thr Asn Ala Arg Ala Pro Glu Cys Met
      50                  55                  60                
 Ala Leu Lys Ala Asp Val Val Ala Lys Lys Arg Ala Tyr Asn Glu Ala
  65                  70                  75                  80
 Glu Val Leu Tyr Asn Arg Ser Leu Asn Glu Tyr Lys Ala Leu Lys Lys
                  85                  90                  95    
 Asp Asp Glu Gln Leu Cys Lys Arg Ile Glu Glu Leu Lys Lys Ser Thr
             100                 105                 110        
 Asp Gln Ser Leu Glu Pro Glu Arg Leu Glu Arg Gln Lys Lys Ile Ser
         115                 120                 125            
 Trp Leu Lys Glu Arg Val Lys Ala Phe Gln Asn Gln Glu Asn Ser Val
     130                 135                 140                
 Asn Gln Glu Ile Glu Gln Phe Gln Gln Ala Ile Glu Lys Asp Lys Glu
 145                 150                 155                 160
 Glu His Gly Lys Ile Lys Arg Glu Glu Leu Asp Val Lys His Ala Leu
                 165                 170                 175    
 Ser Tyr Asn Gln Gly Gln Leu Lys Glu Leu Lys Asp Ser Lys Thr Asp
             180                 185                 190        
 Arg Leu Lys Arg Phe Gly Pro Asn Val Pro Ala Leu Leu Glu Ala Ile
         195                 200                 205            
 Asp Asp Ala Tyr Arg Gln Gly His Phe Thr Tyr Lys Pro Val Gly Pro
     210                 215                 220                
 Leu Gly Ala Cys Ile His Leu Arg Asp Pro Glu Leu Ala Leu Ala Ile
 225                 230                 235                 240
 Glu Ser Cys Leu Lys Gly Leu Leu Gln Ala Tyr Cys Cys His Asn His
                 245                 250                 255    
 Ala Asp Glu Arg Val Leu Gln Ala Leu Met Lys Arg Phe Tyr Leu Pro
             260                 265                 270        
 Trp Thr Ser Arg Pro Pro Ile Ile Val Ser Glu Cys Arg Asn Glu Ile
         275                 280                 285            
 Tyr Asp Val Arg His Arg Ala Ala Tyr His Pro Asp Phe Pro Thr Val
     290                 295                 300                
 Leu Thr Ala Leu Glu Ile Asp Asn Ala Val Ala Ala Asn Ser Leu Ile
 305                 310                 315                 320
 Asp Met Arg Gly Ile Glu Thr Val Leu Leu Ile Lys Asn Asn Ser Val
                 325                 330                 335    
 Ala Arg Ala Val Met Gln Ser Gln Lys Pro Pro Lys Asn Cys Arg Glu
             340                 345                 350        
 Ala Phe Thr Ala Asp Gly Asp Gln Val Phe Ala Gly Arg Tyr Tyr Ser
         355                 360                 365            
 Ser Glu Asn Thr Arg Pro Lys Phe Leu Ser Arg Asp Val Asp Ser Glu
     370                 375                 380                
 Ile Ser Asp Leu Glu Asn Glu Val Glu Asn Lys Thr Ala Gln Ile Leu
 385                 390                 395                 400
 Asn Leu Gln Gln His Leu Ser Ala Leu Glu Lys Asp Ile Lys His Asn
                 405                 410                 415    
 Glu Glu Leu Leu Lys Arg Cys Gln Leu His Tyr Lys Glu Leu Lys Met
             420                 425                 430        
 Lys Ile Arg Lys Asn Ile Ser Glu Ile Arg Glu Leu Glu Asn Ile Glu
         435                 440                 445            
 Glu His Gln Ser Val Asp Ile Ala Thr Leu Glu Asp Glu Ala Gln Glu
     450                 455                 460                
 Asn Lys Ser Lys Met Lys Met Val Glu Glu His Met Glu Gln Gln Lys
 465                 470                 475                 480
 Glu Asn Met Glu His Leu Lys Ser Leu Lys Ile Glu Ala Glu Asn Lys
                 485                 490                 495    
 Tyr Asp Ala Ile Lys Phe Lys Ile Asn Gln Leu Ser Glu Leu Ala Asp
             500                 505                 510        
 Pro Leu Lys Asp Glu Leu Asn Leu Ala Asp Ser Glu Val Asp Asn Gln
         515                 520                 525            
 Lys Arg Gly Lys Arg His Tyr Glu Glu Lys Gln Lys Glu His Leu Asp
     530                 535                 540                
 Thr Leu Asn Lys Lys Lys Arg Glu Leu Asp Met Lys Glu Lys Glu Leu
 545                 550                 555                 560
 Glu Glu Lys Met Ser Gln Ala Arg Gln Ile Cys Pro Glu Arg Ile Glu
                 565                 570                 575    
 Val Glu Lys Ser Ala Ser Ile Leu Asp Lys Glu Ile Asn Arg Leu Arg
             580                 585                 590        
 Gln Lys Ile Gln Ala Glu His Ala Ser His Gly Asp Arg Glu Glu Ile
         595                 600                 605            
 Met Arg Gln Tyr Gln Glu Ala Arg Glu Thr Tyr Leu Asp Leu Asp Ser
     610                 615                 620                
 Lys Val Arg Thr Leu Lys Lys Phe Ile Lys Leu Leu Gly Glu Ile Met
 625                 630                 635                 640
 Glu His Arg Phe Lys Thr Tyr Gln Gln Phe Arg Arg Cys Leu Thr Leu
                 645                 650                 655    
 Arg Cys Lys Leu Tyr Phe Asp Asn Leu Leu Ser Gln Arg Ala Tyr Cys
             660                 665                 670        
 Gly Lys Met Asn Phe Asp His Lys Asn Glu Thr Leu Ser Ile Ser Val
         675                 680                 685            
 Gln Pro Gly Glu Gly Asn Lys Ala Ala Phe Asn Asp Met Arg Ala Leu
     690                 695                 700                
 Ser Gly Gly Glu Arg Ser Phe Ser Thr Val Cys Phe Ile Leu Ser Leu
 705                 710                 715                 720
 Trp Ser Ile Ala Glu Ser Pro Phe Arg Cys Leu Asp Glu Phe Asp Val
                 725                 730                 735    
 Tyr Met Asp Met Val Asn Arg Arg Ile Ala Met Asp Leu Ile Leu Lys
             740                 745                 750        
 Met Ala Asp Ser Gln Arg Phe Arg Gln Phe Ile Leu Leu Thr Pro Gln
         755                 760                 765            
 Ser Met Ser Ser Leu Pro Ser Ser Lys Leu Ile Arg Ile Leu Arg Met
     770                 775                 780                
 Ser Asp Pro Glu Arg Gly Gln Thr Thr Leu Pro Phe Arg Pro Val Thr
 785                 790                 795                 800
 Gln Glu Glu Asp Asp Asp Gln Arg
                 805            



      <210> 2722
      <211> 140
      <212> PRT
      <213> Homo sapiens


      <400> 2722
 Ala Glu Val Leu Gly Arg Ala Val Glu Pro Pro Pro Gly Arg Cys Trp
   1               5                  10                  15    
 Ser Thr Pro Pro Val Ala Pro Pro Ala Arg Ser Ala Ser Ala Ala Ala
              20                  25                  30        
 Met Gly Val Gln Val Glu Thr Ile Ser Pro Gly Asp Gly Arg Thr Phe
          35                  40                  45            
 Pro Lys Arg Gly Gln Thr Cys Val Val His Tyr Thr Gly Met Leu Glu
      50                  55                  60                
 Asp Gly Lys Lys Phe Asp Ser Ser Arg Asp Arg Asn Lys Pro Phe Lys
  65                  70                  75                  80
 Phe Met Leu Gly Lys Gln Glu Val Ile Arg Gly Trp Glu Glu Gly Val
                  85                  90                  95    
 Ala Gln Met Ser Val Gly Gln Arg Ala Lys Leu Thr Ile Ser Pro Asp
             100                 105                 110        
 Tyr Ala Tyr Gly Ala Thr Gly His Pro Gly Ile Ile Pro Pro His Ala
         115                 120                 125            
 Thr Leu Val Phe Asp Val Glu Leu Leu Lys Leu Glu
     130                 135                 140



      <210> 2723
      <211> 95
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(95)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2723
 Arg Arg Val Gly Cys Arg Cys Phe His Pro Ser Gln Thr Gly Thr Cys
   1               5                  10                  15    
 Thr Xaa Arg Pro Pro Trp Asn Val His His Xaa Pro Ala Thr Cys His
              20                  25                  30        
 Leu Ala Tyr Asn Arg His Ser Trp Ser Pro His Arg Ala His Trp His
          35                  40                  45            
 Ile Ala Thr Ala Ile Gln Leu Ser Ala His Val Phe Ala Cys His Tyr
      50                  55                  60                
 Gln Gln Leu His His Tyr His Gln His His His His His His His Tyr
  65                  70                  75                  80
 Arg His His His His His His His His His Tyr Cys His His His
                  85                  90                  95



      <210> 2724
      <211> 156
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(156)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2724
 Pro Met Ala Leu Trp Ala Asp Gly Arg Ala Arg His Lys Val Gly Thr
   1               5                  10                  15    
 Glu Cys Glu Cys Gly Met His Pro Gly Leu Lys Cys Ser Gly Arg Thr
              20                  25                  30        
 Leu Gly Ser Gln Thr Met Leu Ala Thr Thr Pro Cys Asp Ser Pro Thr
          35                  40                  45            
 Xaa Ile Ser Asn Lys Asn Gly Leu Arg Ser Val Ser Tyr Arg Xaa Cys
      50                  55                  60                
 Leu Ile Asn Ala Leu Trp Leu Phe Ser Ile Ser Pro His Ile Leu Val
  65                  70                  75                  80
 Arg Cys Gly Thr Glu Ser Ser Xaa Leu Leu Pro Ser Leu Val Pro Ser
                  85                  90                  95    
 Trp Leu Pro Xaa Leu Val Arg Val Arg Pro Leu Pro Thr Gly Trp Cys
             100                 105                 110        
 Xaa Ile Pro Ser Cys Leu Lys Pro Pro Pro Thr Trp Ser Ser His His
         115                 120                 125            
 Ser Pro Gln Arg Leu Pro Xaa Asn Pro Ala Thr Leu Val Cys Leu Gln
     130                 135                 140                
 Asn Gly Thr Ala Arg Ser His Ser Ser Thr Pro Val
 145                 150                 155    



      <210> 2725
      <211> 166
      <212> PRT
      <213> Homo sapiens


      <400> 2725
 Gly Ser Phe Lys Thr Gly Leu Tyr Leu Pro Thr Ser Asp Ile Asp Leu
   1               5                  10                  15    
 Val Val Phe Gly Lys Trp Glu Asn Leu Pro Leu Trp Thr Leu Glu Glu
              20                  25                  30        
 Ala Leu Arg Lys His Lys Val Ala Asp Glu Asp Ser Val Lys Val Leu
          35                  40                  45            
 Asp Lys Ala Thr Val Pro Ile Ile Lys Leu Thr Asp Ser Phe Thr Glu
      50                  55                  60                
 Val Lys Val Asp Ile Ser Phe Asn Val Gln Asn Gly Val Arg Ala Ala
  65                  70                  75                  80
 Asp Leu Ile Lys Asp Phe Thr Lys Lys Tyr Pro Val Leu Pro Tyr Leu
                  85                  90                  95    
 Val Leu Val Leu Lys Gln Phe Leu Leu Gln Arg Asp Leu Asn Glu Val
             100                 105                 110        
 Phe Thr Gly Gly Ile Gly Ser Tyr Ser Leu Phe Leu Met Ala Val Ser
         115                 120                 125            
 Phe Leu Gln Leu His Pro Arg Glu Asp Ala Cys Ile Pro Asn Thr Asn
     130                 135                 140                
 Tyr Gly Val Leu Leu Ile Glu Phe Phe Glu Leu Tyr Gly Arg His Phe
 145                 150                 155                 160
 Asn Tyr Leu Lys Thr Gly
                 165    



      <210> 2726
      <211> 60
      <212> PRT
      <213> Homo sapiens


      <400> 2726
 Met Thr Leu Arg Met Leu Val Pro Arg Leu Leu Leu Thr Arg Gln Leu
   1               5                  10                  15    
 Val Trp Phe Phe Ser Ala Ala Thr Glu Arg Asp Pro Glu Met Met Asn
              20                  25                  30        
 Gly Ile Pro Arg Lys Leu Met Ser Phe Pro Pro Ser Ser Val Thr Ser
          35                  40                  45            
 Arg Arg Ser Arg Arg Gly His His Leu Gln Ser Leu
      50                  55                  60



      <210> 2727
      <211> 149
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(149)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2727
 Trp Asn Ser Asp Gln Pro Ala Thr Arg Xaa Gln Val Gly Asp Thr Gly
   1               5                  10                  15    
 Ser Leu Pro Ser Arg Lys Gly Gln His Phe Val Leu Thr Gly Ile Asp
              20                  25                  30        
 Thr Tyr Ser Arg Ser Gly Phe Ala Phe Pro Val Arg His Ala Pro Ala
          35                  40                  45            
 Lys Thr Ser Ile Arg Gly Leu Thr Glu Cys Arg Thr Tyr Cys His Gly
      50                  55                  60                
 Met Pro His Cys Thr Ala Ser Val Xaa Gly Thr Pro Phe Thr Ala Lys
  65                  70                  75                  80
 Lys Val Trp Xaa Arg Ala His Ala His Gly Ile Pro Arg Tyr Asp His
                  85                  90                  95    
 Val Ala His His Leu Glu Ala Ala Gly Leu Ile Arg Trp Trp Asn Gly
             100                 105                 110        
 Leu Leu Lys Thr Pro Leu Gln His Gln Leu Gly Gly Asp Ala Leu Gln
         115                 120                 125            
 Gly Trp Ala Arg Val Leu Gln Glu Ala Val Tyr Ala Leu Asn Gln Asn
     130                 135                 140                
 Xaa Val Xaa Gly Trp
 145                



      <210> 2728
      <211> 143
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(143)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2728
 Thr Pro Ser Pro Ser Pro Cys Pro Xaa Pro Arg Pro Leu Ala Ala Leu
   1               5                  10                  15    
 Lys Pro Val Arg Leu His Ser Phe Gln Glu His Val Phe Lys Arg Ala
              20                  25                  30        
 Ser Pro Cys Glu Leu Cys His Gln Leu Ile Val Gly Asn Ser Lys Gln
          35                  40                  45            
 Gly Leu Arg Cys Lys Met Cys Lys Val Ser Val His Leu Trp Cys Ser
      50                  55                  60                
 Glu Glu Ile Ser His Gln Gln Cys Pro Gly Lys Thr Ser Thr Ser Phe
  65                  70                  75                  80
 Arg Arg Asn Phe Ser Ser Pro Leu Leu Val His Glu Pro Pro Pro Val
                  85                  90                  95    
 Cys Ala Thr Ser Lys Glu Ser Pro Pro Thr Gly Asp Ser Gly Lys Val
             100                 105                 110        
 Asp Pro Val Tyr Glu Thr Leu Arg Tyr Gly Thr Ser Leu Ala Leu Met
         115                 120                 125            
 Asn Arg Ser Ser Phe Ser Ser Thr Ser Glu Ser Pro Thr Arg Ser
     130                 135                 140            



      <210> 2729
      <211> 207
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(207)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2729
 Ala Glu Pro Ala Ala Gly Ala Gly Thr Leu Ala Gly Asp Cys Arg Ala
   1               5                  10                  15    
 Val Gln Gly Gly Val His Ala Ala Arg Pro Arg Gly Ala Lys Glu Gly
              20                  25                  30        
 His Gly Pro Ala Asp Gly His Gly Lys Gly Gly Ala Gly Thr Gly Gln
          35                  40                  45            
 Glu Arg Leu Ala Gly Gly Ala Glu Val Cys His Ala Gln Val Arg Gly
      50                  55                  60                
 Gly Ala Ala Ala Pro Gly Cys Arg Val Gly Gly Val Leu Arg Ala Ala
  65                  70                  75                  80
 Lys Ala Glu Xaa Gly Ala Gly Arg Ala Arg Gly Arg Ala Gly Ile Ala
                  85                  90                  95    
 Gly Gly His Pro Ala Gly Gly His Pro His Gln Pro Gly Gln Gly Ala
             100                 105                 110        
 Gly Xaa Ala Glu Asp Gln Gly Gln Arg Ala Pro Gly Arg Gly Glu Ala
         115                 120                 125            
 Ala Gly Ser Gly Arg Gly Ala Gly Pro Gly Ala Gly Ala Ala Gly Ala
     130                 135                 140                
 Ala Ala Gly Glu Gly Glu Asp Gln Arg His Arg Pro Ala Cys Gln Ala
 145                 150                 155                 160
 Pro Arg Arg Gly Gly Gly Glu His Glu Gln Gly Gly Leu Arg Glu Val
                 165                 170                 175    
 Arg Gly Gly Gly Ala Gly Ile Ala Arg Gly Pro Ala Gly Ala Gly Arg
             180                 185                 190        
 Ala Ala Gly Pro Val Ala Gly Gly Ala Ala Thr Ala Gly Ala Ala
         195                 200                 205        



      <210> 2730
      <211> 80
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(80)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2730
 Met Gln Lys Ser Glu Gly Ser Gly Gly Thr Gln Leu Lys Asn Arg Ala
   1               5                  10                  15    
 Thr Gly Asn Tyr Asp Gln Arg Thr Ser Ser Ser Thr Gln Leu Lys His
              20                  25                  30        
 Arg Asn Ala Val Gln Gly Ser Lys Ser Ser Leu Ser Thr Ser Ser Pro
          35                  40                  45            
 Glu Ser Ala Arg Lys Leu His Pro Arg Pro Ser Asp Lys Leu Asn Pro
      50                  55                  60                
 Xaa Thr Ile Asn Pro Val His Ser Asp Asp Glu Val Phe Glu Arg Gly
  65                  70                  75                  80





      <210> 2731
      <211> 107
      <212> PRT
      <213> Homo sapiens


      <400> 2731
 Met Ala Leu Asp Phe Val Asn Val Leu Leu Cys Gln Leu Ala Glu Val
   1               5                  10                  15    
 Thr Leu Gly Val Leu Arg Glu Glu Gly Ala Ser Leu Leu Val Ala Leu
              20                  25                  30        
 Gly Ser Ala Leu Phe Pro Ser Ala Ala Ala Val Gly Lys Gln Gly Ser
          35                  40                  45            
 Met Gly Val Thr Ser His Met Gln Cys Pro Val Cys Gln His Pro Arg
      50                  55                  60                
 Asp Val Leu Leu Ala Ser Pro Val Ser His Ser His Ala Cys Gln Pro
  65                  70                  75                  80
 Gln Pro Ala Gly Cys Ser Asn Cys His Leu Gly His Leu Thr Arg Ser
                  85                  90                  95    
 Pro Pro Phe Gln Gly Leu Leu Pro Leu Leu Gln
             100                 105        



      <210> 2732
      <211> 275
      <212> PRT
      <213> Homo sapiens


      <400> 2732
 Met Lys Arg Tyr Ser Tyr Gly Ser Val Leu Phe Thr Ala Phe Asp Leu
   1               5                  10                  15    
 Gly Tyr Leu Asp Pro Asp Glu Val Gln Gln Gly His Glu Ile Gly Arg
              20                  25                  30        
 Leu Phe Asp Gly Thr Glu Pro Ile Val Leu Asp Ser Leu Lys Gln His
          35                  40                  45            
 Tyr Phe Ile Asp Arg Asp Gly Gln Met Phe Arg Tyr Ile Leu Asn Phe
      50                  55                  60                
 Leu Arg Thr Ser Lys Leu Leu Ile Pro Asp Asp Phe Lys Arg Thr Leu
  65                  70                  75                  80
 Val Phe Ile Leu Pro Leu Ala Ala Pro Phe Ser Val Gly Leu Glu Ala
                  85                  90                  95    
 Cys Pro Leu Ala Gly Lys Arg Leu Lys Gly Ser Val Cys Pro Glu Leu
             100                 105                 110        
 Glu Phe Pro Leu Trp Lys Lys His Arg Val Phe Ser Gln Ser Leu Pro
         115                 120                 125            
 Tyr Lys Thr His Ala Phe Asn Glu Glu Arg Leu Gln Asp Asn Lys Ser
     130                 135                 140                
 Tyr Ile His Ser Val Leu Gln Glu Pro Arg Glu Asp Thr Asp Pro Glu
 145                 150                 155                 160
 Gly Ala Gly Ala Ala Pro Asp His Arg Ser Thr Tyr Lys Leu Leu Ser
                 165                 170                 175    
 Pro Ala Leu Ser Leu Asn Leu Gly Glu Lys Asn Lys Trp Leu Arg Arg
             180                 185                 190        
 Tyr Ile Glu Leu Leu Ile Ser Glu Arg Glu Met Ala Ala Ala Gly Ser
         195                 200                 205            
 Ser Ile Pro Ser Trp Thr Ser Val Ser Ile Gln Val Lys Leu Arg Lys
     210                 215                 220                
 Cys Gln Leu Gln Leu Leu Ala Lys Glu Glu Val Ala Thr Ile Val Leu
 225                 230                 235                 240
 Asp Glu Thr Ser Gly Val Asn Gly Ile His Ile Glu His Gln Leu Gln
                 245                 250                 255    
 Cys Leu Ile Gln Val Pro Lys Leu Ser Ala Pro Asn Ile Ala Pro Pro
             260                 265                 270        
 Thr Pro Ala
         275



      <210> 2733
      <211> 101
      <212> PRT
      <213> Homo sapiens


      <400> 2733
 Gly Met Gly Tyr Leu His Ala Lys Gly Ile Leu His Lys Asp Leu Lys
   1               5                  10                  15    
 Ser Lys Asn Val Phe Tyr Asp Asn Gly Lys Val Val Ile Thr Asp Phe
              20                  25                  30        
 Gly Leu Phe Ser Ile Ser Gly Val Leu Gln Ala Gly Arg Arg Glu Asp
          35                  40                  45            
 Lys Leu Arg Ile Gln Asn Gly Trp Leu Cys His Leu Ala Pro Glu Ile
      50                  55                  60                
 Ile Arg Gln Leu Ser Pro Asp Thr Glu Glu Asp Lys Leu Pro Phe Ser
  65                  70                  75                  80
 Lys His Ser Asp Val Phe Ala Leu Gly Thr Ile Trp Tyr Glu Leu His
                  85                  90                  95    
 Ala Arg Glu Trp Pro
             100    



      <210> 2734
      <211> 195
      <212> PRT
      <213> Homo sapiens


      <400> 2734
 His Thr His Lys Leu Val Ala Pro Arg Pro Gly Leu Pro Pro Thr Ser
   1               5                  10                  15    
 Gln Trp Pro Arg Asp Ala Gly Arg Gln Ala Ser Gly Gly Leu Pro Ser
              20                  25                  30        
 Leu Ser Thr Gly Pro Pro Lys Gly Pro Arg Asp Gly Leu Ala Arg Gly
          35                  40                  45            
 His Pro Ala Glu Trp Leu Ala Gly Ser Pro Gly Asn Asn Ser Pro Thr
      50                  55                  60                
 Gln Gly Ser Leu Pro Pro Gln Leu Asp Leu Tyr Ala Gly Ala Leu Phe
  65                  70                  75                  80
 Val His Ile Cys Leu Gly Trp Asn Phe Tyr Leu Ser Thr Ile Leu Thr
                  85                  90                  95    
 Leu Gly Ile Thr Ala Leu Tyr Thr Ile Ala Gly Met Val Pro Ala Ala
             100                 105                 110        
 Gly Arg Ser Thr Gln Gly Thr Cys Lys Gly Val Arg Arg Pro Pro Pro
         115                 120                 125            
 Pro Thr Gly Pro Arg Glu Gln Pro Arg Lys Trp Pro Gln Gln Glu Pro
     130                 135                 140                
 Gln Lys Phe Leu Pro Val Ser Leu Leu Pro Gly Ala Arg Ala Pro Ser
 145                 150                 155                 160
 Ser Asn Leu Ala Ser Thr Gly Arg Gly Pro Gly Cys Cys Asn Leu His
                 165                 170                 175    
 Gly Arg Pro Ala Asp Ala His His Gly Gly Gly Gly Cys His Pro Asp
             180                 185                 190        
 Asn Gln Arg
         195



      <210> 2735
      <211> 135
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(135)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2735
 Arg His Leu Leu Leu Ser Leu Ser Ala Val Thr Gly Lys Cys Ser Phe
   1               5                  10                  15    
 Ala Pro Asp Cys Gly Glu Leu Lys Leu Pro Gly Ala Ala Cys Ala Cys
              20                  25                  30        
 Gln Val Val Ala Asp Val Ser Ser Leu Leu Leu Xaa Leu Cys Gln Met
          35                  40                  45            
 Arg Glu Leu Arg Cys Glu Asn Val Ala Thr Cys Leu Gly Ile Phe Gly
      50                  55                  60                
 Ser Leu Gly Asn Leu Leu Arg Lys Glu Val Leu His Leu Asp Trp Thr
  65                  70                  75                  80
 Phe Lys Ala Ser Leu Leu Leu Asp Leu Ile Cys Met Arg Ser Leu Pro
                  85                  90                  95    
 Gly Pro Gly Thr Ala Glu Leu Leu Trp Thr Ala Pro Glu Leu Leu Pro
             100                 105                 110        
 Gly Pro Gly Arg Pro Gly Arg Arg Thr Leu Thr Gly Asp Ile Phe Ser
         115                 120                 125            
 Thr Gly Ile Ile Leu Gln Glu
     130                 135



      <210> 2736
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 2736
 Leu Val Asp Pro Arg Val Arg Gly Glu Pro Gly Pro Pro Ser Asp Ala
   1               5                  10                  15    
 Val Phe Ala Arg Asp Pro Met Arg Pro Pro Gly Leu Val Arg Asn Leu
              20                  25                  30        
 Gln Val Thr Asp Arg Ser Asn Thr Ser Ile Thr Leu Ser Trp Ala Gly
          35                  40                  45            
 Pro Asp Thr Gln Glu Gly Asp Glu Ala Gln Gly Tyr Val Val Glu Leu
      50                  55                  60                
 Cys Ser Ser Asn Ser Leu Gln Trp Leu Pro Cys His Val Gly Thr Val
  65                  70                  75                  80
 Pro Val Thr Thr Tyr Thr Ala Lys Gly Leu Arg Pro Gly Glu Gly Tyr
                  85                  90                  95    
 Phe Val Arg Val Thr Ala Val Asn Glu Gly Gly Gln Ser Gln Pro Ser
             100                 105                 110        
 Ala Leu Asp Thr Leu Val Gln Ala Met Pro Val Thr Val Cys Pro Lys
         115                 120                 125            
 Phe Leu Val Asp Ser Ser Thr Lys Asp Leu Leu Thr Val Lys Val Gly
     130                 135                 140                
 Asp Thr Val Arg Val Pro Val Ser Phe Glu His Ala Arg Arg Pro Leu
 145                 150                 155                 160
 Gly Pro Ser Thr Cys Arg Arg Thr Cys Leu Gly Arg
                 165                 170        



      <210> 2737
      <211> 144
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(144)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2737
 Asn Asp Pro Arg Val Gln Lys Pro Arg Glu Glu Ala Pro Ala Gly Ala
   1               5                  10                  15    
 Ala Ala Ser Gly Xaa Cys Gly Arg Xaa Pro Gly Gln His Pro Ala Ala
              20                  25                  30        
 Ala Xaa Pro Xaa Ser Ala Gly Pro Arg Arg Ala Pro Thr Ala Leu Ser
          35                  40                  45            
 Pro Pro Thr Ala Glu Pro Ser Leu Cys Pro Ala Pro Gly Xaa Pro Glu
      50                  55                  60                
 Gln Pro Gln Cys Ser Arg Arg Pro Gly Gly Gln Pro Arg Asp Pro Val
  65                  70                  75                  80
 Gly Gln His Arg Ser Gln Pro Ala Val Gly Pro Ala Ala Gly Ser Pro
                  85                  90                  95    
 Leu Arg Pro Cys Ala Trp Ser Ala Gln Arg Gly Ser Pro Gln Pro Asp
             100                 105                 110        
 Gln Leu Pro His Thr Pro Pro Gly Ala Ala Gly Ser Xaa Ser Gln Leu
         115                 120                 125            
 Pro Arg Pro Pro Pro Ser Phe Ala Gln Ala Thr Pro Ser Thr Pro Pro
     130                 135                 140                





      <210> 2738
      <211> 181
      <212> PRT
      <213> Homo sapiens


      <400> 2738
 Glu Glu Leu Cys Val Arg Glu His Val Thr Gly Gly Ile Cys Gly Gly
   1               5                  10                  15    
 Ser Gln Met Met Val Val Leu Leu Gly Ala Thr Thr Leu Val Leu Val
              20                  25                  30        
 Ala Val Ala Pro Trp Val Leu Ser Ala Ala Ala Gly Glu Arg Arg Gly
          35                  40                  45            
 Gly Glu Ser Trp Arg Arg Ala Gly Gly Arg Ala Arg Ser Trp Ala Thr
      50                  55                  60                
 Gly Ala Ala Met Leu Leu Gly Ala Thr Asp Ala Gln Ser Gly Lys Pro
  65                  70                  75                  80
 Ser Val His Phe Ala Ala Pro Lys Ile Lys Pro Asp Leu Gly Ser Gln
                  85                  90                  95    
 Ile Asn Gln Glu Lys Val Val Phe Trp Val Leu Ser Cys Arg Leu Pro
             100                 105                 110        
 Val Ala Val Tyr Gly Ser Ser Gly Ala Pro Gly Ser His Pro Arg Glu
         115                 120                 125            
 Met Ala Val Pro Glu Leu Cys Val Glu Phe Asp Ser Phe Arg Glu Thr
     130                 135                 140                
 His Gln Ile Leu Leu Val Tyr Phe Val Cys Gly Pro Arg Gln Leu Phe
 145                 150                 155                 160
 Phe Gln Cys Gly Pro Arg Lys Pro Lys Arg Val Asp Thr Leu Asp Ala
                 165                 170                 175    
 Asp Glu Ala Cys Arg
             180    



      <210> 2739
      <211> 136
      <212> PRT
      <213> Homo sapiens


      <400> 2739
 Cys His Ser Thr Glu Ser Ser Ser Asp Phe Ile Leu Pro Gly Asp Tyr
   1               5                  10                  15    
 Leu Leu Gly Gly Leu Cys Pro Leu His Ser Gly Cys Leu Gln Val Cys
              20                  25                  30        
 Ser Phe Asn Glu His Gly Tyr His Leu Phe Gln Ala Met Arg Leu Ala
          35                  40                  45            
 Val Glu Glu Ile Asn Asn Ser Thr Ala Leu Leu Pro Asn Ile Thr Leu
      50                  55                  60                
 Gly Tyr Gln Leu Tyr Asp Val Cys Ser Asp Ser Ala Asn Val Tyr Ala
  65                  70                  75                  80
 Thr Leu Arg Val Leu Ser Leu Pro Gly Gln His His Ile Glu Leu Gln
                  85                  90                  95    
 Gly Asp Leu Leu His Tyr Ser Pro Thr Val Leu Ala Val Ile Gly Pro
             100                 105                 110        
 Asp Ser Thr Asn Arg Ala Ala Thr Thr Ala Ala Leu Leu Ser Pro Phe
         115                 120                 125            
 Leu Val Pro Met Leu Leu Glu Gln
     130                 135    



      <210> 2740
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2740
 Ser Thr Arg Pro Glu Phe Pro Gly Arg Ala Pro Thr Gly Phe Leu Lys
   1               5                  10                  15    
 Leu Leu Ala Asp Lys Asn Ser Glu Leu Phe Arg Lys Tyr Ala Leu Phe
              20                  25                  30        
 Ser Pro Ser Asp His Arg Val Pro Arg Ile Tyr Val Pro Leu Lys Asp
          35                  40                  45            
 Cys Pro Gln Asp Phe Val Ala Arg Pro Lys Asp Tyr Ala Asn Thr Leu
      50                  55                  60                
 Phe Ile Cys Arg Ile Val Asp Trp Lys Glu Asp Cys Asn Phe Ala Leu
  65                  70                  75                  80
 Gly Gln Leu Ala Lys Ser Leu Gly Gln Ala Gly Glu Ile Glu Pro Glu
                  85                  90                  95    
 Thr Glu Gly Ile Leu Thr Glu Tyr Gly Val Asp Phe Ser Asp Phe Ser
             100                 105                 110        
 Ser Glu Val Leu Glu Cys Leu Pro Gln Gly Leu Pro Trp Thr Ile Pro
         115                 120                 125            
 Pro Glu Glu Phe Ser Lys Arg Arg Val Val
     130                 135            



      <210> 2741
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 2741
 Met Ala Pro Ala Ala Asp Arg Glu Gly Tyr Trp Gly Pro Thr Thr Ser
   1               5                  10                  15    
 Thr Leu Asp Trp Cys Glu Glu Asn Tyr Ser Val Thr Trp Tyr Ile Ala
              20                  25                  30        
 Glu Phe Ser Trp Leu Met Ser Gly Phe Leu Pro Thr Pro Ser Ser Leu
          35                  40                  45            
 Arg Asp Leu Thr Ala Ser Arg Trp Val Arg Ser Leu Pro Pro Ser Arg
      50                  55                  60                
 Ser Pro Ala Gly Arg Gln Pro Gly Pro Ala Glu Glu Leu Pro Lys Ala
  65                  70                  75                  80
 Ser Pro Cys Pro Trp Gly Lys Ser Leu Ser Arg Pro Phe Ala Ser Phe
                  85                  90                  95    
 Ser Ala Ser Ser Gly Pro Ser
             100            



      <210> 2742
      <211> 124
      <212> PRT
      <213> Homo sapiens


      <400> 2742
 Phe Arg Asp Leu Gln Cys Ala Leu Tyr Asn Gly Arg Pro Val Leu Gly
   1               5                  10                  15    
 Thr Gln Lys Thr Tyr Gln Trp Val Pro Phe His Gly Ala Pro Asn Gln
              20                  25                  30        
 Cys Asp Leu Asn Cys Leu Ala Glu Gly His Ala Phe Tyr His Ser Phe
          35                  40                  45            
 Gly Arg Val Leu Asp Gly Thr Ala Cys Ser Pro Gly Ala Gln Gly Val
      50                  55                  60                
 Cys Val Ala Gly Arg Cys Leu Ser Ala Gly Cys Asp Gly Leu Leu Gly
  65                  70                  75                  80
 Ser Gly Ala Leu Glu Asp Arg Cys Gly Arg Cys Gly Gly Ala Asn Asp
                  85                  90                  95    
 Ser Cys Leu Phe Val Gln Arg Val Phe Arg Asp Ala Gly Ala Phe Ala
             100                 105                 110        
 Gly Tyr Trp Asn Val Thr Leu Ile Pro Glu Gly Ala
         115                 120                



      <210> 2743
      <211> 113
      <212> PRT
      <213> Homo sapiens


      <400> 2743
 Met Gly Pro Val Pro Leu Val Trp Ala Met Ser Gln Leu Ser Leu Ser
   1               5                  10                  15    
 Ala Lys Met Asp Arg Arg Arg Thr Gly Val Met Met Thr Ser Thr Pro
              20                  25                  30        
 Ile Thr Trp Gly Thr Leu Glu Lys Thr Met Gln Glu Ala Glu Lys Leu
          35                  40                  45            
 Leu Glu Arg Gln Gly Gln Thr Lys Thr Pro Asp Ser Met Phe Leu Ala
      50                  55                  60                
 Met Glu Glu Ser Leu Asn Val Thr Phe Val Lys Asn Ile Thr Thr Gln
  65                  70                  75                  80
 Phe Met Val Cys Gly Phe Asn Pro Tyr Val Phe Leu Ala Ala Lys Ala
                  85                  90                  95    
 Asp Gln Leu Gln Val Val Val Ser His Thr Thr Thr Ala Ser Gln Glu
             100                 105                 110        
 Arg
    



      <210> 2744
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 2744
 Met Ile Leu Ile Asn Phe Arg Glu Ile Cys Leu Lys Val Leu His Thr
   1               5                  10                  15    
 Pro Leu Cys Val Ser Gly Gly Cys Val Leu Leu Tyr Ile Leu Ala Leu
              20                  25                  30        
 Thr Cys Cys Tyr Thr Asn Ser Leu Leu Ile Ser His Leu Pro Pro Leu
          35                  40                  45            
 Ser Leu Pro Thr Glu Thr Gln Thr His Leu Phe Met Tyr Arg Val Leu
      50                  55                  60                
 Lys Val Arg Lys Asp Ile Lys Asn His Val Phe His Pro Thr Tyr Leu
  65                  70                  75                  80
 Val Ala Lys Glu Thr Glu Thr Tyr Gly Glu Glu Leu Ile Pro Leu Pro
                  85                  90                  95    
 Pro Cys Arg Glu His Gln Asp
             100            



      <210> 2745
      <211> 1298
      <212> PRT
      <213> Homo sapiens


      <400> 2745
 Asn Arg Pro Ser Ser Ala Ser Ser Thr Ser Ser Lys Ala Pro Pro Ser
   1               5                  10                  15    
 Ser Arg Arg Asn Val Gly Met Gly Thr Thr Arg Arg Leu Gly Ser Ser
              20                  25                  30        
 Thr Leu Gly Ser Lys Ser Ser Ala Ala Lys Glu Gly Ala Gly Ala Val
          35                  40                  45            
 Asp Glu Glu Asp Phe Ile Lys Ala Phe Asp Asp Val Pro Val Val Gln
      50                  55                  60                
 Ile Tyr Ser Ser Arg Asp Leu Glu Glu Ser Ile Asn Lys Ile Arg Glu
  65                  70                  75                  80
 Ile Leu Ser Asp Asp Lys His Asp Trp Glu Gln Arg Val Asn Ala Leu
                  85                  90                  95    
 Lys Lys Ile Arg Ser Leu Leu Leu Ala Gly Ala Ala Glu Tyr Asp Asn
             100                 105                 110        
 Phe Phe Gln His Leu Arg Leu Leu Asp Gly Ala Phe Lys Leu Ser Ala
         115                 120                 125            
 Lys Asp Leu Arg Ser Gln Val Val Arg Glu Ala Cys Ile Thr Leu Gly
     130                 135                 140                
 His Leu Ser Ser Val Leu Gly Asn Lys Phe Asp His Gly Ala Glu Ala
 145                 150                 155                 160
 Ile Met Pro Thr Ile Phe Asn Leu Ile Pro Asn Ser Ala Lys Ile Met
                 165                 170                 175    
 Ala Thr Ser Gly Val Val Ala Val Arg Leu Ile Ile Arg His Thr His
             180                 185                 190        
 Ile Pro Arg Leu Ile Pro Val Ile Thr Ser Asn Cys Thr Ser Lys Ala
         195                 200                 205            
 Val Ala Val Arg Arg Arg Cys Phe Glu Phe Leu Asp Leu Leu Leu Gln
     210                 215                 220                
 Glu Trp Gln Thr His Ser Leu Glu Arg His Ile Ser Val Leu Ala Glu
 225                 230                 235                 240
 Thr Ile Lys Lys Gly Ile His Asp Ala Asp Ser Glu Ala Arg Ile Glu
                 245                 250                 255    
 Ala Arg Lys Cys Tyr Trp Gly Phe His Ser His Phe Ser Arg Glu Ala
             260                 265                 270        
 Glu His Leu Tyr His Thr Leu Glu Ser Ser Tyr Gln Lys Ala Leu Gln
         275                 280                 285            
 Ser His Leu Lys Asn Ser Asp Ser Ile Val Ser Leu Pro Gln Ser Asp
     290                 295                 300                
 Arg Ser Ser Ser Ser Ser Gln Glu Ser Leu Asn Arg Pro Leu Ser Ala
 305                 310                 315                 320
 Lys Arg Ser Pro Thr Gly Ser Thr Thr Ser Arg Ala Ser Thr Val Ser
                 325                 330                 335    
 Thr Lys Ser Val Ser Thr Thr Gly Ser Leu Gln Arg Ser Arg Ser Asp
             340                 345                 350        
 Ile Asp Val Asn Ala Ala Ala Ser Ala Lys Ser Lys Val Ser Ser Ser
         355                 360                 365            
 Ser Gly Thr Thr Pro Phe Ser Ser Ala Ala Ala Leu Pro Pro Gly Ser
     370                 375                 380                
 Tyr Ala Ser Leu Asp Gly Thr Thr Thr Lys Ala Glu Gly Arg Ile Arg
 385                 390                 395                 400
 Thr Arg Arg Gln Ser Ser Gly Ser Ala Thr Asn Val Ala Ser Thr Pro
                 405                 410                 415    
 Asp Asn Arg Gly Arg Ser Arg Ala Lys Val Val Ser Gln Ser Gln Arg
             420                 425                 430        
 Ser Arg Ser Ala Asn Pro Ala Gly Ala Gly Ser Arg Ser Ser Ser Pro
         435                 440                 445            
 Gly Lys Leu Leu Gly Ser Gly Tyr Gly Gly Leu Thr Gly Gly Ser Ser
     450                 455                 460                
 Arg Gly Pro Pro Val Thr Pro Ser Ser Glu Lys Arg Ser Lys Ile Pro
 465                 470                 475                 480
 Arg Ser Gln Gly Cys Ser Arg Glu Thr Ser Pro Asn Arg Ile Gly Leu
                 485                 490                 495    
 Ala Arg Ser Ser Arg Ile Pro Arg Pro Ser Met Ser Gln Gly Cys Ser
             500                 505                 510        
 Arg Asp Thr Ser Arg Glu Ser Ser Arg Asp Thr Ser Pro Ala Arg Gly
         515                 520                 525            
 Phe Pro Pro Leu Asp Arg Phe Gly Leu Gly Gln Pro Gly Arg Ile Pro
     530                 535                 540                
 Gly Ser Val Asn Ala Met Arg Val Leu Ser Thr Ser Thr Asp Leu Glu
 545                 550                 555                 560
 Ala Ala Val Ala Asp Ala Leu Lys Lys Pro Val Arg Arg Arg Tyr Glu
                 565                 570                 575    
 Pro Tyr Gly Met Tyr Ser Asp Asp Asp Ala Asn Ser Asp Ala Ser Ser
             580                 585                 590        
 Val Cys Ser Glu Arg Ser Tyr Gly Ser Arg Asn Gly Gly Ile Pro His
         595                 600                 605            
 Tyr Leu Arg Gln Thr Glu Asp Val Ala Glu Val Leu Asn His Cys Ala
     610                 615                 620                
 Ser Ser Asn Trp Ser Glu Arg Lys Glu Gly Leu Leu Gly Leu Gln Asn
 625                 630                 635                 640
 Leu Leu Lys Ser Gln Arg Thr Leu Ser Arg Val Glu Leu Lys Arg Leu
                 645                 650                 655    
 Cys Glu Ile Phe Thr Arg Met Phe Ala Asp Pro His Ser Lys Arg Val
             660                 665                 670        
 Phe Ser Met Phe Leu Glu Thr Leu Val Asp Phe Ile Ile Ile His Lys
         675                 680                 685            
 Asp Asp Leu Gln Asp Trp Leu Phe Val Leu Leu Thr Gln Leu Leu Lys
     690                 695                 700                
 Lys Asn Gly Glu Ala Asp Leu Leu Gly Ser Val Gln Ala Lys Val Gln
 705                 710                 715                 720
 Lys Ala Leu Asp Val Thr Arg Asp Ser Phe Pro Phe Asp Gln Gln Phe
                 725                 730                 735    
 Asn Ile Leu Met Arg Phe Ile Val Asp Gln Thr Gln Thr Pro Asn Leu
             740                 745                 750        
 Lys Val Lys Val Ala Ile Leu Lys Tyr Ile Glu Ser Leu Ala Arg Gln
         755                 760                 765            
 Met Asp Pro Thr Asp Phe Val Asn Ser Ser Glu Thr Arg Leu Ala Val
     770                 775                 780                
 Ser Arg Ile Ile Thr Trp Thr Thr Glu Pro Lys Ser Ser Asp Val Arg
 785                 790                 795                 800
 Lys Ala Ala Gln Ile Val Leu Ile Ser Leu Phe Glu Leu Asn Thr Pro
                 805                 810                 815    
 Glu Phe Thr Met Leu Leu Gly Ala Leu Pro Lys Thr Phe Gln Asp Gly
             820                 825                 830        
 Ala Thr Lys Leu Leu His Asn His Leu Lys Asn Ser Ser Asn Thr Ser
         835                 840                 845            
 Val Gly Ser Pro Ser Asn Thr Ile Gly Arg Thr Pro Ser Arg His Thr
     850                 855                 860                
 Ser Ser Arg Thr Ser Pro Leu Thr Ser Pro Thr Asn Cys Ser His Gly
 865                 870                 875                 880
 Gly Leu Ser Pro Ser Arg Leu Trp Gly Trp Ser Ala Asp Gly Leu Ala
                 885                 890                 895    
 Lys His Pro Pro Pro Phe Ser Gln Pro Asn Ser Ile Pro Thr Ala Pro
             900                 905                 910        
 Ser His Lys Ala Leu Arg Arg Ser Tyr Ser Pro Ser Met Leu Asp Tyr
         915                 920                 925            
 Asp Thr Glu Asn Leu Asn Ser Glu Glu Ile Tyr Ser Ser Leu Arg Gly
     930                 935                 940                
 Val Thr Glu Ala Ile Glu Lys Phe Ser Phe Arg Ser Gln Glu Asp Leu
 945                 950                 955                 960
 Asn Glu Pro Ile Lys Arg Asp Gly Lys Lys Glu Cys Asp Ile Val Ser
                 965                 970                 975    
 Arg Asp Gly Gly Ala Ala Ser Pro Ala Thr Glu Gly Arg Gly Gly Ser
             980                 985                 990        
 Glu Val Glu Gly Gly Arg Thr Ala Leu Asp Asn Lys Thr Ser Leu Leu
         995                1000                1005            
 Asn Thr Gln Pro Pro Arg Ala Phe Pro Gly Pro Arg Ala Arg Asp Tyr
    1010                1015                1020                
 Asn Pro Tyr Pro Tyr Ser Asp Ala Ile Asn Thr Tyr Asp Lys Thr Ala
1025                1030                1035                1040
 Leu Lys Glu Ala Val Phe Asp Asp Asp Met Glu Gln Leu Arg Asp Val
                1045                1050                1055    
 Pro Ile Asp His Ser Asp Leu Val Ala Asp Leu Leu Lys Glu Leu Ser
            1060                1065                1070        
 Asn His Asn Glu Arg Val Glu Glu Arg Lys Gly Ala Leu Leu Glu Leu
        1075                1080                1085            
 Leu Lys Ile Thr Arg Glu Asp Ser Leu Gly Val Trp Glu Glu His Phe
    1090                1095                1100                
 Lys Thr Ile Leu Leu Leu Leu Leu Glu Thr Leu Gly Asp Lys Asp His
1105                1110                1115                1120
 Ser Ile Arg Ala Leu Ala Leu Arg Val Leu Arg Glu Ile Leu Arg Asn
                1125                1130                1135    
 Gln Pro Ala Arg Phe Lys Asn Tyr Ala Glu Leu Thr Ile Met Lys Thr
            1140                1145                1150        
 Leu Glu Ala His Lys Asp Ser His Lys Glu Val Val Arg Ala Ala Glu
        1155                1160                1165            
 Glu Ala Ala Ser Thr Leu Ala Ser Ser Ile His Pro Glu Gln Cys Ile
    1170                1175                1180                
 Lys Val Leu Cys Pro Ile Ile Gln Thr Ala Asp Tyr Pro Ile Asn Leu
1185                1190                1195                1200
 Ala Ala Ile Lys Met Gln Thr Lys Val Val Glu Arg Ile Ala Lys Glu
                1205                1210                1215    
 Ser Leu Leu Gln Leu Leu Val Asp Ile Ile Pro Gly Leu Leu Gln Gly
            1220                1225                1230        
 Tyr Asp Asn Thr Glu Ser Ser Val Arg Lys Ala Ser Val Phe Cys Leu
        1235                1240                1245            
 Val Ala Ile Tyr Ser Val Ile Gly Glu Asp Leu Lys Pro His Leu Ala
    1250                1255                1260                
 Gln Leu Thr Gly Ser Lys Met Lys Leu Leu Asn Leu Tyr Ile Lys Arg
1265                1270                1275                1280
 Ala Gln Thr Thr Asn Ser Asn Ser Ser Ser Ser Ser Asp Val Ser Thr
                1285                1290                1295    
 His Ser
        



      <210> 2746
      <211> 357
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(357)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2746
 Arg Val Phe Ser Glu Ser Val Cys Ser Pro Val Arg Asn Leu Glu Phe
   1               5                  10                  15    
 Leu Trp Arg Phe Ala Phe Pro Leu Ala Pro Ala Gly Arg Cys Pro Pro
              20                  25                  30        
 Gly Val Pro Leu Gln Thr Ser Pro Arg Asp Thr Asp Ala His Arg Ser
          35                  40                  45            
 Ser Pro Leu Pro Pro Ala Arg Ala Ser Pro Gly Gln Val Ala Ala Ala
      50                  55                  60                
 Tyr Arg Trp Ala Arg Cys Pro Gly Cys Gly Gly Arg Lys Pro Arg Ser
  65                  70                  75                  80
 Ser Gly Ser Trp Gln Leu Cys Arg Cys Pro Thr Leu Pro Pro Pro Pro
                  85                  90                  95    
 Arg Gly Ser Arg Ser Ser Gly Arg Cys Arg Thr Trp Pro Ser Pro Pro
             100                 105                 110        
 Ser Cys Phe Pro His Phe Gln Ser Gly Pro Arg Thr Thr Arg Ala Pro
         115                 120                 125            
 Thr Pro Ser Thr Ile Pro Gly Tyr Ser Gly Ser Tyr Ser Ser Gly Pro
     130                 135                 140                
 Gly Arg Xaa Gly Leu Ser Pro Leu His Ala Ala Val Ser Pro Pro Leu
 145                 150                 155                 160
 Pro Pro Gly Gly Pro Xaa Gly Ser Trp Ala Arg Ala Gly Leu Gly Ser
                 165                 170                 175    
 Ile Ala Ser Ala His Ser Pro Cys Pro Leu Cys Arg Ser Leu Ile Arg
             180                 185                 190        
 Ser Arg Ser Xaa Gln Thr Cys Thr Arg Ser Pro Thr Xaa Asn Cys Glu
         195                 200                 205            
 Val Pro Pro Ser Ala Pro Xaa Ala Ala Ser Pro Leu Arg Thr Met Phe
     210                 215                 220                
 Ala Leu Val Arg Thr Ala Gly Leu Lys Val His Leu Leu Pro Leu Gly
 225                 230                 235                 240
 Tyr Cys Thr Thr Met Ser Xaa Ser Ser Ser Met Pro Gln Thr Val Pro
                 245                 250                 255    
 Val Val Val Lys Val Ser Asn Ile Pro Ser Val His Pro Pro Xaa Pro
             260                 265                 270        
 Cys Cys Lys Asp Cys Thr Ile Ser Arg Ser Arg Ser Ile Phe Thr Arg
         275                 280                 285            
 Ser Pro Ile Cys Asn Pro Pro Gly Phe Leu Leu Pro Phe Cys Ser Pro
     290                 295                 300                
 Ser Thr Gly Gln Xaa Ser Leu Xaa Lys Glu Pro Pro Leu Ala Ser Trp
 305                 310                 315                 320
 Thr His Phe Arg Ser Asp Val Leu Leu Leu Phe Ser Val Ser Met Asn
                 325                 330                 335    
 Gly Ser Thr Leu Ser Leu Gly Cys Pro Ser Gln Lys Ala Val Ile Ala
             340                 345                 350        
 Leu Val Gln Val Thr
         355        



      <210> 2747
      <211> 332
      <212> PRT
      <213> Homo sapiens


      <400> 2747
 Met Lys Ile His Ser Cys Ala Phe Val Ile Glu Gln Glu Glu Lys Lys
   1               5                  10                  15    
 Lys Thr Glu Ala His Lys Glu Gly Asp Gly Val Lys Arg Ala Asp Lys
              20                  25                  30        
 Ile Leu Gly Val Thr Lys Asp Pro Gly Thr Ile Ala Gly Leu Asn Val
          35                  40                  45            
 Val Arg Ile Ile Asn Glu Pro Thr Ala Ala Ser Ile Ala Tyr Gly Thr
      50                  55                  60                
 Asp Lys Lys Phe Gly Ala Glu Arg His Val Leu Ile Tyr Asp Leu Arg
  65                  70                  75                  80
 Asp Glu Ile Phe Asp Val Ser Val Leu Thr Leu Glu Asp Glu Ile Phe
                  85                  90                  95    
 Glu Ile Lys Ser Thr Ala Gly Asp Thr His Leu Gly Glu Glu Asp Phe
             100                 105                 110        
 Asp Asn Gln Met Ile Asn His Phe Ile Ala Glu Phe Lys Tyr Lys His
         115                 120                 125            
 Lys Asp Ser Arg Ala Asp Ile Tyr Thr Ser Ile Thr His Ala Gln Phe
     130                 135                 140                
 Glu Glu Leu Asn Ala Val Leu Phe Arg Gly Thr Gln Asp Pro Ile Glu
 145                 150                 155                 160
 Ile Ala Leu Gln Asp Thr Lys Leu Asp Lys Leu Gln Ile His Val Ile
                 165                 170                 175    
 Val Leu Thr Gln Thr Phe Thr Thr Tyr Pro Asp Asn Gln Pro Asp Val
             180                 185                 190        
 Leu Ile Gln Val Tyr Glu Gly Glu Ser Ala Ile Thr Lys Asp Asn Asn
         195                 200                 205            
 Leu Leu Val Ile Gln Gly Lys Phe Glu Leu Thr Gly Ile Leu Pro Ala
     210                 215                 220                
 Pro Phe Ala Val Pro Gln Ile Lys Val Thr Cys Asp Ile Asp Val Asn
 225                 230                 235                 240
 Ser Ser Leu Asn Ile Ser Ala Val Gly Lys Ser Thr Glu Lys Glu Asn
                 245                 250                 255    
 Lys Ile Ile Ile Thr Asn Asp Gln Gly His Leu Ser Lys Glu Asp Ile
             260                 265                 270        
 Glu Asn Met Val Gln Glu Ala Glu Tyr Lys Ala Glu Asp Glu Lys Gln
         275                 280                 285            
 Lys Asn Lys Val Ala Ser Lys Asn Ser Leu Asp Ser Tyr Ala Phe Asn
     290                 295                 300                
 Met Lys Ala Thr Glu Lys Leu Gln Gly Lys Ile Asn Asn Lys Asp Lys
 305                 310                 315                 320
 Gln Lys Ile Leu Asp Lys Cys Asn Lys Ile Ile Asn
                 325                 330        



      <210> 2748
      <211> 379
      <212> PRT
      <213> Homo sapiens


      <400> 2748
 Ile Pro Pro Pro Ser Ser Pro Ser Ser Pro Ala Ala Ala Pro Arg Ala
   1               5                  10                  15    
 Gln Leu Gly Lys Asp Ala Leu Ser Pro Leu Ala Leu Leu Leu Arg Pro
              20                  25                  30        
 Arg Arg Ala Tyr Pro Arg Pro Leu Pro Thr Ser Glu Ser Leu Ala Trp
          35                  40                  45            
 Gly Ser Pro Pro Pro Ser Arg Phe Gly Pro Ser Pro Ala Ser Gln Pro
      50                  55                  60                
 Arg Ser Pro Arg Leu Ser Phe Leu Val Leu Gly Val Ala Cys Ser Ala
  65                  70                  75                  80
 Ile Leu Met Tyr Ile Phe Cys Thr Asp Cys Trp Leu Ile Ala Val Leu
                  85                  90                  95    
 Tyr Phe Thr Trp Leu Val Phe Asp Trp Asn Thr Pro Lys Lys Gly Gly
             100                 105                 110        
 Arg Arg Ser Gln Trp Val Arg Asn Trp Ala Val Trp Arg Tyr Phe Arg
         115                 120                 125            
 Asp Tyr Phe Pro Ile Gln Leu Val Lys Thr His Asn Leu Leu Thr Thr
     130                 135                 140                
 Arg Asn Tyr Ile Phe Gly Tyr His Pro His Gly Ile Met Gly Leu Gly
 145                 150                 155                 160
 Ala Phe Cys Asn Phe Ser Thr Glu Ala Thr Glu Val Ser Lys Lys Phe
                 165                 170                 175    
 Pro Gly Ile Arg Pro Tyr Leu Ala Thr Leu Ala Gly Asn Phe Arg Met
             180                 185                 190        
 Pro Val Leu Arg Glu Tyr Leu Met Ser Gly Gly Ile Cys Pro Val Ser
         195                 200                 205            
 Arg Asp Thr Ile Asp Tyr Leu Leu Ser Lys Asn Gly Ser Gly Asn Ala
     210                 215                 220                
 Ile Ile Ile Val Val Gly Gly Ala Ala Glu Ser Leu Ser Ser Met Pro
 225                 230                 235                 240
 Gly Lys Asn Ala Val Thr Leu Arg Asn Arg Lys Gly Phe Val Lys Leu
                 245                 250                 255    
 Ala Leu Arg His Gly Ala Asp Leu Val Pro Ile Tyr Ser Phe Gly Glu
             260                 265                 270        
 Asn Glu Val Tyr Lys Gln Val Ile Phe Glu Glu Gly Ser Trp Gly Arg
         275                 280                 285            
 Trp Val Gln Lys Lys Phe Gln Lys Tyr Ile Gly Phe Ala Pro Cys Ile
     290                 295                 300                
 Phe His Gly Arg Gly Leu Phe Ser Ser Asp Thr Trp Gly Leu Val Pro
 305                 310                 315                 320
 Tyr Ser Lys Pro Ile Thr Thr Val Val Gly Glu Pro Ile Thr Ile Pro
                 325                 330                 335    
 Lys Leu Glu His Pro Thr Gln Gln Asp Ile Asp Leu Tyr His Thr Met
             340                 345                 350        
 Tyr Met Glu Ala Leu Val Lys Leu Phe Asp Lys His Lys Thr Lys Phe
         355                 360                 365            
 Gly Leu Pro Glu Thr Glu Val Leu Glu Val Asn
     370                 375                



      <210> 2749
      <211> 49
      <212> PRT
      <213> Homo sapiens


      <400> 2749
 Asp Leu Tyr Ser Glu Lys Ala Ser Ala Asp His Glu Gly Ala Glu Gln
   1               5                  10                  15    
 Phe Thr Asp Glu Phe Ala Lys Val Ile Ala Asp Gly Asn Leu Met Pro
              20                  25                  30        
 Glu Gln Val Tyr Asn Ala Val Lys Thr Ser Leu Phe Trp Cys Met Val
          35                  40                  45            
 Pro
    



      <210> 2750
      <211> 57
      <212> PRT
      <213> Homo sapiens


      <400> 2750
 Met Leu Glu Gln Ala Ser Leu Trp Leu Gly Arg Ser Phe Leu Leu Ala
   1               5                  10                  15    
 Gly Phe Leu Val Ser Ser Ser Cys Pro Ser Leu Glu Gln Ala Ala Lys
              20                  25                  30        
 Gly Glu Gly Cys Ser Pro Ile Pro Cys Phe Ala His Cys Leu Asp Ser
          35                  40                  45            
 Leu Val Arg Asn Phe Leu Cys His Pro
      50                  55        



      <210> 2751
      <211> 469
      <212> PRT
      <213> Homo sapiens


      <400> 2751
 Gly Pro Leu Ile Asp Leu Cys Lys Gly Pro His Glu Thr His Thr Gly
   1               5                  10                  15    
 Lys Ile Lys Thr Ile Gln Ile Phe Thr Asn Ser Ser Thr Tyr Trp Glu
              20                  25                  30        
 Gly Asn Pro Glu Met Glu Thr Leu Gln Arg Ile Tyr Gly Ile Ser Phe
          35                  40                  45            
 Pro Asp Asn Lys Met Met Arg Asp Trp Glu Lys Phe Gln Glu Glu Ala
      50                  55                  60                
 Lys Asn Arg Asp His Arg Lys Ile Gly Lys Glu Gln Glu Leu Phe Phe
  65                  70                  75                  80
 Phe His Asp Leu Ser Pro Gly Ser Cys Phe Phe Leu Pro Arg Gly Ala
                  85                  90                  95    
 Phe Ile Tyr Asn Thr Leu Thr Asp Phe Ile Arg Glu Glu Tyr His Lys
             100                 105                 110        
 Arg Asp Phe Thr Glu Val Leu Ser Pro Asn Met Tyr Asn Ser Lys Leu
         115                 120                 125            
 Trp Glu Ala Ser Gly His Trp Gln His Tyr Ser Glu Asn Met Phe Thr
     130                 135                 140                
 Phe Glu Ile Glu Lys Asp Thr Phe Ala Leu Lys Pro Met Asn Cys Pro
 145                 150                 155                 160
 Gly His Cys Leu Met Phe Ala His Arg Pro Arg Ser Trp Arg Glu Met
                 165                 170                 175    
 Pro Ile Arg Phe Ala Asp Phe Gly Val Leu His Arg Asn Glu Leu Ser
             180                 185                 190        
 Gly Thr Leu Ser Gly Leu Thr Arg Val Arg Arg Phe Gln Gln Asp Asp
         195                 200                 205            
 Ala His Ile Phe Cys Thr Val Glu Gln Ile Glu Glu Glu Ile Lys Gly
     210                 215                 220                
 Cys Leu Gln Phe Leu Gln Ser Val Tyr Ser Thr Phe Gly Phe Ser Phe
 225                 230                 235                 240
 Gln Leu Asn Leu Ser Thr Arg Pro Glu Asn Phe Leu Gly Glu Ile Glu
                 245                 250                 255    
 Met Trp Asn Glu Ala Glu Lys Gln Leu Gln Asn Ser Leu Met Asp Phe
             260                 265                 270        
 Gly Glu Pro Trp Lys Met Asn Pro Gly Asp Gly Ala Phe Tyr Gly Pro
         275                 280                 285            
 Lys Ile Asp Ile Lys Ile Lys Asp Ala Ile Gly Arg Tyr His Gln Cys
     290                 295                 300                
 Ala Thr Ile Gln Leu Asp Phe Gln Leu Pro Ile Arg Phe Asn Leu Thr
 305                 310                 315                 320
 Tyr Val Ser Lys Asp Gly Asp Asp Lys Lys Arg Pro Val Ile Ile His
                 325                 330                 335    
 Arg Ala Ile Leu Gly Ser Val Glu Arg Met Ile Ala Ile Leu Ser Glu
             340                 345                 350        
 Asn Tyr Gly Gly Lys Trp Pro Phe Trp Leu Ser Pro Arg Gln Val Met
         355                 360                 365            
 Val Ile Pro Val Gly Pro Thr Cys Glu Lys Tyr Ala Leu Gln Val Ser
     370                 375                 380                
 Ser Glu Phe Phe Glu Glu Gly Phe Met Ala Asp Val Asp Leu Asp His
 385                 390                 395                 400
 Ser Cys Thr Leu Asn Lys Lys Ile Arg Asn Ala Gln Leu Ala Gln Tyr
                 405                 410                 415    
 Asn Phe Ile Leu Val Val Gly Glu Lys Glu Lys Ile Asp Asn Ala Val
             420                 425                 430        
 Asn Val Arg Thr Arg Asp Asn Lys Ile His Gly Glu Ile Leu Val Thr
         435                 440                 445            
 Ser Ala Ile Asp Lys Leu Lys Asn Leu Arg Lys Thr Arg Thr Leu Asn
     450                 455                 460                
 Ala Glu Glu Ala Phe
 465                



      <210> 2752
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 2752
 Met Val Ala Ser Phe Arg Glu Ser Arg Val Leu Leu Leu Gly Leu Val
   1               5                  10                  15    
 Val Arg Val Leu Thr Phe Asp Phe Leu Thr Gln Val Val Arg Val Gly
              20                  25                  30        
 Ser Glu Cys Gly Asp Glu Leu Val Arg Leu Tyr Ser Phe Thr Asp Glu
          35                  40                  45            
 Lys Ala Asn Tyr Leu Gln Gln Gly Gly Cys Arg
      50                  55                



      <210> 2753
      <211> 187
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(187)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2753
 Leu Arg Ser Ile Tyr Thr Thr His Tyr Arg Glu Ser Val Pro Lys Ala
   1               5                  10                  15    
 His Leu Thr Asp Ser Phe Pro Asp Leu Leu Gly Leu Ala Ala Glu Asp
              20                  25                  30        
 Xaa His Cys Pro Ile Ala Leu Glu Ala Leu Xaa Thr Ile Thr Asp Ala
          35                  40                  45            
 Glu Leu Arg Val Thr Leu Thr Val Glu Gly Lys Pro Val Pro Phe Leu
      50                  55                  60                
 Ile Asn Thr Glu Ala Thr His Ser Thr Leu Pro Ser Phe Gln Gly Pro
  65                  70                  75                  80
 Val Ser Leu Ala Ser Ile Thr Val Val Gly Ile Asp Gly Gln Ala Ser
                  85                  90                  95    
 Lys Pro Leu Lys Thr Pro Gln Leu Trp Cys Gln His Xaa Thr Ile Arg
             100                 105                 110        
 Arg Phe Lys His Ser Phe Leu Val Ile Pro Thr Cys Gln Val Pro Leu
         115                 120                 125            
 Leu Gly Glu Asp Thr Leu Thr Lys Leu Ser Ala Ser Leu Thr Ile Pro
     130                 135                 140                
 Gly Leu Gln Leu Tyr Leu Ile Ala Thr Leu Leu Pro Asn Pro Lys Pro
 145                 150                 155                 160
 Pro Leu Cys Pro Pro Leu Val Ser Pro Gln Leu Asn Pro Gln Val Xaa
                 165                 170                 175    
 Asp Ile Ser Thr Pro Ser Leu Thr Thr Asp Ser
             180                 185        



      <210> 2754
      <211> 64
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(64)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2754
 Gly Leu Gly Pro His Asp Tyr Leu Tyr Ser Ile Leu Ser Ile Glu Arg
   1               5                  10                  15    
 Ser Cys Cys Cys Xaa Cys Cys Cys Cys Cys Cys Arg Arg Arg Arg Cys
              20                  25                  30        
 Cys Cys Cys Cys Cys Val Xaa Gly Cys Ser Arg Phe Leu Cys Ser Ile
          35                  40                  45            
 Ala Glu Ser Thr Pro Ser Gly Ala Leu Arg Arg Leu Arg Gly Gly Arg
      50                  55                  60                





      <210> 2755
      <211> 168
      <212> PRT
      <213> Homo sapiens


      <400> 2755
 Ala Ser Ala Leu Leu Phe Val Val Gly Phe Ala Glu Ser Leu Arg Glu
   1               5                  10                  15    
 Phe Thr Ala Asp Cys Pro Pro Tyr Lys Cys Pro Val Ala Pro Glu Pro
              20                  25                  30        
 Leu Pro Gln Pro Leu Ser Pro Leu Gln Cys Pro Gly Glu Glu Ser Thr
          35                  40                  45            
 Asp Ser Pro Phe Ser Leu Pro Thr Val Gln Pro Val Lys Ser Arg Cys
      50                  55                  60                
 Ser Pro Phe Ile Glu Glu Ser Pro Arg Ala Asn Arg Ser Ile Pro Ala
  65                  70                  75                  80
 Phe Gly Ser His Leu Glu Cys Ala Ser Cys Ser Ser Arg Ser Phe His
                  85                  90                  95    
 Gly Pro Pro Pro Cys Cys Leu Trp Gly Leu Pro Leu Ser Ala Pro Ser
             100                 105                 110        
 Pro His Val Leu His Pro Pro Ala Ser Ala Ala Ile Gly Pro Ala Cys
         115                 120                 125            
 Cys Val Thr Ser Leu Cys Pro Gly Ala Pro Gln Ala Gln Arg Pro Arg
     130                 135                 140                
 Lys Val Asp Gln Thr Ser Ser Ala Pro Gly Ala Gly Pro Gly Thr Gln
 145                 150                 155                 160
 Asp Gly Asn Glu Arg Pro Asn Pro
                 165            



      <210> 2756
      <211> 1202
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1202)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2756
 Tyr Trp Lys Glu Arg Pro Thr Gln Lys Val Ile Pro Arg Ala Thr Glu
   1               5                  10                  15    
 Asn His Gly Leu Lys Ser Tyr Leu Gln Lys Thr Lys Leu Ser Ile Asp
              20                  25                  30        
 Glu Ala Ala Phe Leu Leu Pro Asp Thr Asn Leu Lys Ser Glu Leu Leu
          35                  40                  45            
 Glu Leu Leu Thr His Trp Leu Gln Val Gly Val Pro Met Thr Pro Ser
      50                  55                  60                
 Leu Gly Ser Ile Asn Leu Leu Gly Trp Leu Thr Glu Leu Arg Glu Thr
  65                  70                  75                  80
 His Thr Tyr Ile Cys Trp Phe Ile Val Lys Glu Thr Thr Arg Asp Thr
                  85                  90                  95    
 Asp Glu Glu Met Cys Arg Thr Glu Pro Ala Leu Ala Cys Ser Ile Ser
             100                 105                 110        
 His Tyr Cys Asp Asp Gly Cys Ile Gln Met Leu Asn Thr Pro Glu Thr
         115                 120                 125            
 Leu Gln Cys Ser Ala Lys Asp Ser Lys His Phe Ile Pro Lys Glu Cys
     130                 135                 140                
 Ser Ile Pro Gly Glu Asn Arg Pro Pro Ser Asp Thr Gly Lys Thr Val
 145                 150                 155                 160
 Lys Phe Leu Ser Leu Asn Ile Phe Asn Leu Gln Leu Ala Glu Ser Thr
                 165                 170                 175    
 Asp Ala Glu Gln Arg Ala Asn Cys Ile Leu Arg Cys Phe Leu Thr Glu
             180                 185                 190        
 Thr Thr Leu Asn Tyr Gln Lys Ile Leu Ser Val Arg Pro Gly Thr Lys
         195                 200                 205            
 Leu Ala Thr Ala Ser His Val Ser Gly Leu Gly Leu Gln Thr Pro Pro
     210                 215                 220                
 Phe Gly Leu Ala Gln His Leu Ile Arg Pro His Ala Phe Leu Ala Pro
 225                 230                 235                 240
 Lys Asp Pro Leu Thr Ser Phe Thr Glu Arg Asn Ser Arg Ser Gly Lys
                 245                 250                 255    
 Thr Arg Cys Arg Ser Lys Lys Cys Ala Met Arg Val Val Lys Ser Tyr
             260                 265                 270        
 Ser Ala Ile Leu Pro Lys Lys Arg Glu Ser Val Leu Thr Lys Thr Leu
         275                 280                 285            
 Leu Val Ala Pro Thr Asn Glu Gln Thr Asp Pro Val Leu Arg Met Cys
     290                 295                 300                
 Cys Gly Lys Thr Gly Leu Lys Lys Gly Ala Gly Phe Thr Leu Glu Ser
 305                 310                 315                 320
 Arg Gly Gln Arg Arg Met Arg Ala Gly Cys Pro Thr Leu Cys Val Arg
                 325                 330                 335    
 Ala Arg Val Thr Glu Thr Asp Pro Ser Ile Cys Ser Glu Val Thr Phe
             340                 345                 350        
 Ser Trp Met Ile Leu Met Leu Met Asp Val Cys Gln Cys Leu Gly Ile
         355                 360                 365            
 Glu Glu Phe Gly Ile Tyr Cys Ser Leu Arg Ser Leu Asp Leu Phe Val
     370                 375                 380                
 Pro Ile Phe Leu Glu Lys Val Phe Gln Val Phe Glu Gly Thr Ser Ser
 385                 390                 395                 400
 Pro Ile Met Leu Trp Phe Leu Gln Thr His Arg Gly Thr Thr Leu Val
                 405                 410                 415    
 Ala Leu Asp Lys Ile Gln Lys Asn Ser Leu Asp Tyr Gln Ala Glu Thr
             420                 425                 430        
 Leu Val Leu Phe Pro Tyr Phe Leu Pro Asn Lys Trp Asn Leu Ser Val
         435                 440                 445            
 Phe Ala Glu Pro Pro Gly Thr Gly Asp Val Val Met Gln Ala Pro Leu
     450                 455                 460                
 Trp Pro Pro Pro Leu Gly Leu Tyr Trp Ala Leu Glu His Tyr Asp Gln
 465                 470                 475                 480
 His Val Ala Lys Pro Ala Arg Gln Arg Ser Leu Ser Leu Trp Pro Pro
                 485                 490                 495    
 Pro Pro Thr Ala His Lys Gly Phe Leu Gln Gly His Cys Gln Cys Ser
             500                 505                 510        
 Leu Lys Thr Gln Arg Leu Phe Ser Gln Leu Met Ala Asn Ala Ala Arg
         515                 520                 525            
 Pro Glu Thr Gln Ala Ser Gly Gln Trp Thr Pro Phe Ser Pro Gly Gln
     530                 535                 540                
 Ile Gln Lys Cys Ser Pro Arg Ser Arg Asn Ala Leu Gly Thr Pro Arg
 545                 550                 555                 560
 Ala Cys Leu Leu Leu Tyr Pro Thr Val Ala Glu Leu Gly Ser Thr Glu
                 565                 570                 575    
 Phe Asn Val Lys Pro Ser Ile Cys Cys Thr Leu Pro Tyr Gln Gly Ala
             580                 585                 590        
 Gln Ser Pro Ser Leu His Thr Leu Gln Leu Arg Gly Asn Gly Val Gly
         595                 600                 605            
 Gly Gln His Gln Gln Phe Lys Thr Val Ser Leu Asp Pro Phe Asn Ala
     610                 615                 620                
 Ser Phe Arg Asp Met Lys Leu Lys Leu Gly Lys Ser Gly Ile Ser Ser
 625                 630                 635                 640
 Trp Phe Val Ser Ile Ala Ala Ala Val Gly Asp Glu Gly Leu Val Pro
                 645                 650                 655    
 Arg Ser Met Glu Leu Tyr Ser Gln Lys Ala Tyr Asp Cys Leu Cys Cys
             660                 665                 670        
 Val Met Gln Val Val Arg Lys Val Gly Glu Ser Trp Gln Ser Gln Thr
         675                 680                 685            
 Ser Pro Ser Ser His Thr Thr Gln Lys Ala Asn Leu Thr Ser Thr Leu
     690                 695                 700                
 Pro Pro Thr Thr Ala Leu Ser Val Phe Pro Gly Ser Gly Tyr Gln Glu
 705                 710                 715                 720
 Trp Gly Thr Ala Val Lys Ile Leu Glu Ser Met Glu Ala Thr Leu Glu
                 725                 730                 735    
 Gln Asp Asn Lys Thr Arg Leu Glu Gln Phe Gly Gly Phe Arg Arg Lys
             740                 745                 750        
 Glu Asp Arg Lys Met Trp Glu Ser Leu Glu Leu Pro Arg Asp Leu Trp
         755                 760                 765            
 Asn Asp Phe Asp Gln Asn Ala Asp Ser Asp Met Asp Asn Glu Val Gln
     770                 775                 780                
 Ala Glu Val Val Ser Asp Gly Asp Lys Glu Leu Val Arg Asn Trp Ser
 785                 790                 795                 800
 Lys Val Trp Lys Gly Asn Val Gly Leu Glu Pro Arg Tyr Arg Val Pro
                 805                 810                 815    
 Thr Gly Ala Leu Thr Ser Arg Val Val Arg Arg Gly Pro Pro Ser Phe
             820                 825                 830        
 Arg Pro Gln Lys Cys Arg Ser Thr Asp Ser Leu His His Glu Pro Gly
         835                 840                 845            
 Lys Ala Ala Gly Thr Gln Cys Gln Pro Val Lys Asp Leu Pro Lys Ala
     850                 855                 860                
 Val Gly Ala His Ser Leu His Gln Pro Ala Leu Asp Phe Arg Gln Glu
 865                 870                 875                 880
 Tyr Leu Asn Pro Phe Ser Lys Asn Ala Lys Phe Gln Tyr Glu Cys Gly
                 885                 890                 895    
 Asn Tyr Ser Gly Ala Ala Glu Asn Phe Tyr Phe Phe Lys Gly Leu Val
             900                 905                 910        
 Pro Ala Thr Asp Arg Asn Ala Leu Ser Ser Leu Trp Gly Lys Leu Ala
         915                 920                 925            
 Ser Glu Ile Leu Met Gln Asn Trp Asp Ala Ala Met Glu Asp Leu Thr
     930                 935                 940                
 Arg Leu Lys Glu Thr Ile Asp Asn Asn Asp Glu Lys Pro Ser Phe Thr
 945                 950                 955                 960
 His Val Val Gly Lys Glu Arg Tyr Leu Asn Ala Ile Gln Thr Met Cys
                 965                 970                 975    
 Pro Gln Phe Phe Arg Tyr Leu Xaa Leu Thr Ala Val His Asn Lys Gln
             980                 985                 990        
 Gly Ile Val Arg Lys Arg Arg Pro Arg Val Xaa Lys Ile Xaa Leu Ser
         995                1000                1005            
 Phe Ile Lys Gln Glu Ser Tyr Thr Tyr Lys Arg Pro Asn Leu Gln Asn
    1010                1015                1020                
 Leu Leu Glu Cys Leu Tyr Val Asn Phe Asp Phe Asp Gly Gly Ser Arg
1025                1030                1035                1040
 Lys Ser Xaa Gly Glu Cys Glu Pro Gly Leu Val Asn Asp Phe Phe Leu
                1045                1050                1055    
 Gly Gly Xaa Ser Xaa Gly Phe Gln Xaa Lys Met Pro Arg Leu Phe Ile
            1060                1065                1070        
 Phe Glu Thr Phe Cys Arg Ile Pro Pro Ser Val Ser Ala Ile Asn Met
        1075                1080                1085            
 Leu Ala Asp Lys Leu Asn Met Thr Pro Glu Glu Ala Glu Arg Val Asp
    1090                1095                1100                
 Trp Xaa Asn Leu Ile Arg Lys Trp Gln Ala Trp Met Pro Gln Asp Leu
1105                1110                1115                1120
 Ile Pro Lys Leu Gly Ser Cys Gly Leu Trp Gly Asn Asn Ala Val Ser
                1125                1130                1135    
 Pro Leu Gln Gln Val Ile Glu Lys Thr Lys Ser Leu Ser Phe Arg Ser
            1140                1145                1150        
 Pro Asp Val Gly Pro Xaa Ile Met Arg Lys Asn Leu Asn Gln Asn Ser
        1155                1160                1165            
 Arg Ser Glu Ala Pro Xaa Arg Gly Gln Leu Gln Asp Ser Gly Leu Leu
    1170                1175                1180                
 Leu Lys Asn His Lys Glu Lys Met Lys Lys Lys Asn Tyr Gln Arg Lys
1185                1190                1195                1200
 Met Lys
        



      <210> 2757
      <211> 1030
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(1030)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2757
 Met His Lys Glu Leu Pro Ala Leu Ala Ala Cys Gly Leu Val Ala Asp
   1               5                  10                  15    
 Phe Asp Pro Val Gly Glu Glu Glu Thr Ala Asp Phe Gly Pro Leu Val
              20                  25                  30        
 Leu Asp Ser Asp Ser Asp Asp Ser Val Asp Arg Asp Ile Glu Glu Ala
          35                  40                  45            
 Ile Gln Glu Tyr Leu Lys Val Gly Ser Ser Lys Asp Gln Gly Ser Ala
      50                  55                  60                
 Ser Pro Val Ser Met Ser Arg Ala Asp Ser Phe Glu Gln Ser Ile Arg
  65                  70                  75                  80
 Ala Glu Ile Glu Gln Phe Leu Asn Glu Lys Arg Gln His Glu Thr Gln
                  85                  90                  95    
 Lys Cys Asp Gly Ser Val Glu Lys Lys Pro Asp Thr His Glu Asn Ser
             100                 105                 110        
 Ala Lys Ser Leu Ser Lys Ser His Gln Glu Pro Ala Thr Lys Val Val
         115                 120                 125            
 His Arg Gln Gly Leu Met Gly Val Gln Lys Glu Phe Ala Phe Cys Arg
     130                 135                 140                
 Pro Pro Arg Leu Ala Lys Thr Asn Val Gln Pro Arg Ser Leu Arg Ser
 145                 150                 155                 160
 Lys Val Thr Thr Thr Thr Thr Gln Glu Lys Glu Gly Ser Thr Lys Pro
                 165                 170                 175    
 Ala Thr Pro Thr Arg Pro Ser Glu Ala Val Gln Asn Lys Ser Gly Ile
             180                 185                 190        
 Lys Arg Ser Ala Ser Thr Ala Arg Arg Gly Lys Arg Val Thr Ser Ala
         195                 200                 205            
 Val Gln Ala Pro Glu Ala Ser Asp Ser Ser Ser Asp Asp Gly Ile Glu
     210                 215                 220                
 Glu Ala Ile Gln Leu Tyr Gln Val Gln Lys Thr His Lys Glu Ala Asp
 225                 230                 235                 240
 Gly Asp Pro Pro Gln Arg Val Gln Leu Gln Glu Glu Arg Ala Pro Ala
                 245                 250                 255    
 Pro Pro Ala His Ser Thr Ser Ser Ala Thr Lys Ser Ala Leu Pro Glu
             260                 265                 270        
 Thr His Arg Lys Thr Pro Ser Lys Lys Lys Pro Val Pro Thr Lys Thr
         275                 280                 285            
 Thr Asp Pro Gly Pro Gly Asp Leu Asp Ala Asp His Ser Pro Lys Ile
     290                 295                 300                
 Pro Lys Glu Thr Lys Ala Pro Pro Pro Thr Ser Pro Ala Ser Arg Ser
 305                 310                 315                 320
 Lys Phe Val Glu Trp Ser Ser Cys Gln Ala Asp Thr Ser Ala Glu Leu
                 325                 330                 335    
 Ile Ala Val Leu Asp Ile Phe Lys Thr Ile Leu Pro Ala Pro Met Glu
             340                 345                 350        
 Gly Ser Asp Gly Ser Leu Ser Ala Ser Pro Leu Phe Tyr Ser Pro Asn
         355                 360                 365            
 Val Pro Ser Arg Ser Asp Gly Asp Ser Ser Ser Val Asp Ser Asp Asp
     370                 375                 380                
 Ser Ile Glu Gln Glu Ile Trp Thr Phe Leu Ala Leu Lys Gly Thr Ala
 385                 390                 395                 400
 Ser Glu Ala Pro Gly Gly Glu Gly Ala Ala Arg Val Pro Gly Asp Thr
                 405                 410                 415    
 Arg Thr Ser Gln Gly Gln Gly Lys Thr Asp Glu Ala Arg His Leu Asp
             420                 425                 430        
 Lys Lys Lys Ser Ser Glu Asp Lys Ser Ser Ser Leu Asp Ser Asp Lys
         435                 440                 445            
 Asp Leu Asp Thr Ala Ile Lys Asp Leu Leu Arg Arg Val Pro Gly Pro
     450                 455                 460                
 Ser Ser Gln Pro Trp Leu Leu Val Xaa Gln Gln Gln Phe Ser Gly Gln
 465                 470                 475                 480
 Arg Arg Xaa His Arg Thr Gly Asp Xaa Glu Val Phe Gly Gly Lys Gly
                 485                 490                 495    
 Gln Gly Val Gly Ser Pro Arg Pro Gly Pro Ala Leu Ser Leu Glu Ala
             500                 505                 510        
 His Thr Cys Trp Arg Arg Arg Thr Ala Ile Thr Gly Gln Ala Gly Arg
         515                 520                 525            
 Cys Leu Cys Tyr Asp Ser Gln Asp Pro Lys Cys Gly Asp Leu Lys Lys
     530                 535                 540                
 Pro Ser Lys Lys Arg Val Lys Arg Lys Pro Tyr Ser Thr Thr Lys Val
 545                 550                 555                 560
 Thr Ser Gly Ser Thr Phe Asn Glu Asn Thr Arg Arg Tyr Ala Val His
                 565                 570                 575    
 Thr Asn Gln Cys Arg Arg Pro His Gly Ser Arg Val Lys Lys Lys Arg
             580                 585                 590        
 Tyr Pro Gln Glu Asp Asp Phe His His Thr Val Phe Ser Asn Leu Glu
         595                 600                 605            
 Arg Leu Asp Lys Leu Gln Pro Thr Leu Glu Ala Ser Glu Glu Ser Leu
     610                 615                 620                
 Val His Lys Asp Arg Gly Asp Gly Glu Arg Pro Val Asn Val Arg Val
 625                 630                 635                 640
 Val Gln Val Ala Pro Leu Arg Leu Glu Ser Ser Lys Tyr Thr Gly Ile
                 645                 650                 655    
 Thr Cys Gln Glu Asn Asn Leu Asp Ala Lys Lys Ala Pro His Glu Asp
             660                 665                 670        
 Thr Val His Asp Ile Thr Asn Glu Asp Ala Thr His Asp Ile Ala Asn
         675                 680                 685            
 Glu Asp Thr Val His Asp Ile Ala Asn Glu Ala Ala Asp Lys Gly Ile
     690                 695                 700                
 Ala Asn Glu Asp Ala Ala His Gly Ile Ala Ser Glu Asp Ala Ala His
 705                 710                 715                 720
 Gly Ile Ala Ser Glu Asp Ala Ala Gln Gly Ile Ala Ser Glu Asp Ala
                 725                 730                 735    
 Ala Gln Gly Ile Ala Ser Glu Asp Ala Ala Gln Gly Ile Ala Lys Glu
             740                 745                 750        
 Asp Ala Ala Gln Gly Ile Ala Asn Glu Asp Ala Ala Gln Gly Ile Ala
         755                 760                 765            
 Asn Glu Gly Ala Ala Gln Gly Ile Ala Lys Glu Asp Ala Ala Gln Gly
     770                 775                 780                
 Ile Ala Lys Glu Gly Ala Ala His Gly Ile Ala Asn Glu Asp Ala Ala
 785                 790                 795                 800
 Gln Gly Ile Ala Asn Glu Asp Ser Ala His Gly Ile Ala Ser Glu Asp
                 805                 810                 815    
 Ala Ala His Gly Ile Ala Ile Ala Asn Glu Asp Ala Ile Tyr Asp Ile
             820                 825                 830        
 Ala Asn Asp Thr Val Gln Gly Thr Leu Thr Arg Thr Leu Tyr Thr Thr
         835                 840                 845            
 Ser Leu Met Arg Thr Pro Tyr Lys Ala Leu Val Met Arg Thr Leu Tyr
     850                 855                 860                
 Met Thr Ser Leu Thr Arg Thr Leu Tyr Lys Pro Ser Leu Thr Arg Thr
 865                 870                 875                 880
 Leu Tyr Thr Thr Ser Leu Met Thr Ala Pro Tyr Lys Thr Ser Pro Met
                 885                 890                 895    
 Arg Ala Leu Tyr Thr Thr Leu Leu Met Ile Pro Thr Arg His Ala Asn
             900                 905                 910        
 Ala Asp Thr Val His Asp Ile Ala Asn Glu Asp Ser Val Tyr Asp Ile
         915                 920                 925            
 Ala Asn Glu Gly Ala Val Tyr Asp Ile Ala Asn Asp Thr Val Gln Gly
     930                 935                 940                
 Thr Leu Thr Arg Thr Leu Tyr Thr Thr Ser Leu Met Arg Thr Pro Tyr
 945                 950                 955                 960
 Lys Ala Ser Val Met Arg Thr Leu Tyr Thr Thr Ser Leu Thr Arg Thr
                 965                 970                 975    
 Pro Tyr Lys Pro Ser Leu Thr Arg Thr Leu Tyr Thr Thr Ser Leu Met
             980                 985                 990        
 Thr Ala Pro Tyr Lys Thr Ser Pro Met Arg Ala Leu Tyr Thr Thr Leu
         995                1000                1005            
 Leu Met Ile Pro Thr Arg His Ala Asn Val Asp Ala Val His Asp Ile
    1010                1015                1020                
 Ala Asn Glu Asp Thr Val
1025                1030



      <210> 2758
      <211> 342
      <212> PRT
      <213> Homo sapiens


      <400> 2758
 Met Thr Leu Gly Pro Leu Thr Asn Gln Arg Lys Glu His Leu Thr Asn
   1               5                  10                  15    
 Phe Lys Ser Val Ser Thr Pro Ser Ser Glu Ser Phe Glu Cys Phe Phe
              20                  25                  30        
 Ser Thr Asp Ser Ser Asp Leu Ser Pro Ser Pro Gln Ala Ala Arg Arg
          35                  40                  45            
 Gln Ala Glu Pro Gly Ala Cys Phe Lys Cys Trp Lys Ser Gly His Trp
      50                  55                  60                
 Ala Glu Glu Cys Leu Gln Pro Arg Ile Pro Pro Lys Leu His Pro Ile
  65                  70                  75                  80
 Cys Val Gly Pro His Trp Lys Ser Asp Cys Pro Ala His Leu Ala Ala
                  85                  90                  95    
 Thr Pro Arg Ala Ala Gly Thr Leu Ala Gln Gly Ser Leu Thr Pro Ser
             100                 105                 110        
 Gln Ile Phe Leu Ala Glu Trp Leu Lys Thr Asp Thr Ala Arg Ser Pro
         115                 120                 125            
 Gln Lys Pro Pro Gly Pro Ser Gln Thr Leu Trp Val Thr Leu Thr Val
     130                 135                 140                
 Glu Val Ala Ala Thr Ala Leu Ile Leu Leu Glu Ala Leu Lys Ile Thr
 145                 150                 155                 160
 Ser Tyr Ala Pro Leu Thr Leu Tyr Ser Ser His Asn Phe Gln Asn Leu
                 165                 170                 175    
 Phe Ser Ser Ser His Leu Thr His Ile Leu Ser Ala Pro Lys Thr Leu
             180                 185                 190        
 Gln Leu Tyr Ser Leu Phe Val Glu Ser Ser Thr Ile Thr Ile Val Ala
         195                 200                 205            
 Gly Pro Asp Phe Asn Pro Ala Ser His Ile Ile Pro Asp Thr Thr Pro
     210                 215                 220                
 Asp Pro His Asp Cys Ile Ser Leu Ile His Leu Thr Phe Ile Pro Phe
 225                 230                 235                 240
 Pro His Ile Ser Phe Phe Pro Val Pro His Pro Asp His Thr Trp Phe
                 245                 250                 255    
 Ile Asp Gly Ser Ser Thr Arg Pro Asn Arg His Thr Pro Ala Lys Ala
             260                 265                 270        
 Gly Tyr Ala Ile Val Ser Ser Thr Phe Ile Ile Glu Ala Thr Ala Leu
         275                 280                 285            
 Pro Pro Ser Thr Thr Ser Gln Gln Ala Lys Leu Ile Ala Leu Thr Gln
     290                 295                 300                
 Ala Leu Thr Leu Ala Lys Gly Leu Leu Val Asn Ile Tyr Thr Asp Ser
 305                 310                 315                 320
 Lys Tyr Ala Phe His Ile Gln Tyr His His Ala Val Ile Trp Ala Glu
                 325                 330                 335    
 Arg Asn Phe Leu Thr Thr
             340        



      <210> 2759
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2759
 Thr Arg Lys Cys Gly Gln Leu Pro Arg Ser Val Ser Leu Pro Ser Gly
   1               5                  10                  15    
 Pro Gln Pro Leu Pro Gly Ser Val Arg His Pro Arg Pro Val Leu Arg
              20                  25                  30        
 Arg Pro Leu Pro Arg Ala Gln Gly Ser Ser Ser Ser Phe Arg Pro Arg
          35                  40                  45            
 Pro Pro Phe Ala Pro Asp Thr Met Asp Lys Phe Trp Trp His Ala Ala
      50                  55                  60                
 Trp Gly Leu Cys Leu Val Pro Leu Ser Leu Ala Gln Ile Gly Glu Cys
  65                  70                  75                  80
 Pro Pro Gln Pro Gly Gln Gln Asp Gly Cys Gly Val Leu Ser Ala Asp
                  85                  90                  95    
 Pro Ala Ala Ala Pro Pro Ala Glu Ser Ala Leu Gly Asp Trp Ser Gln
             100                 105                 110        
 Val Ser Cys Leu Arg Ser Ala Leu Gly Ser Gly Lys Gln Gly Trp
         115                 120                 125        



      <210> 2760
      <211> 74
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(74)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2760
 Ala Arg Pro Ser Arg Val Glu Ala Gln Met Leu Gly Ala Arg Arg Ala
   1               5                  10                  15    
 Ala Ser Trp Leu Trp Ala Pro Trp Phe Cys Pro Asn Glu Gly Xaa Asn
              20                  25                  30        
 Gln Pro Gly Gln His Ser Glu Thr Pro Ser Leu Gln Lys Val Leu Lys
          35                  40                  45            
 Pro Gly Met Val Val His Leu Leu Trp Ser Gln Leu Leu Gly Ser Leu
      50                  55                  60                
 Arg Trp Glu Asp Arg Leu Ser Pro Gly Asp
  65                  70                



      <210> 2761
      <211> 116
      <212> PRT
      <213> Homo sapiens


      <400> 2761
 Asn Gln Thr Pro Phe Phe Phe Phe Phe Phe Gly Gly Thr Glu Thr Thr
   1               5                  10                  15    
 Ser Thr Thr Leu Cys Ser Tyr Gly Leu Leu Ile Leu Leu Lys Tyr Pro
              20                  25                  30        
 Glu Val Ala Glu Ser Ala Ser Gln Arg Asp Pro Glu Trp Glu Ala Ala
          35                  40                  45            
 Val Trp Arg Trp Leu Glu Gly Pro Gly Ser Ala Gln Pro Pro Ser Ala
      50                  55                  60                
 Pro Ala Lys Gly Gln Glu Leu Asp Pro Val Val Gly Gln Arg Pro Val
  65                  70                  75                  80
 Pro Ser Pro Asp Asp His Val Gln Trp Pro Tyr Thr Asn Ala Val Leu
                  85                  90                  95    
 Leu Glu Ile Gln Arg Phe Ile Ser Val Val Lys Arg Thr Leu Thr Leu
             100                 105                 110        
 Asp Thr Leu Tyr
         115    



      <210> 2762
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 2762
 Met Thr Gly Ile Val Ala Lys Gln Asn Ser Ala Ser Val Pro Leu Pro
   1               5                  10                  15    
 Ala Arg Leu Val Arg Pro Thr Val Asn Arg Lys Leu Leu Gly Ala Gly
              20                  25                  30        
 Thr Gly Ser Leu Pro Arg Lys Glu Ala Arg Arg Glu Arg Phe Leu Asp
          35                  40                  45            
 Gly Asp Gln Asp Gly Asp Glu Gly Pro Arg Gln Pro Ser Met Gly Leu
      50                  55                  60                
 Pro His Lys Gln Val Gln Asn Arg Ala Met Ala Lys Val Val Ile Thr
  65                  70                  75                  80
 Phe Ala Pro Thr Asn Ala Met Gln Leu Ala Arg Ser Pro Lys Thr Leu
                  85                  90                  95    
 Asn Phe Met Lys Ile Ile Gly Glu Met Glu Ser Val Leu Glu
             100                 105                 110



      <210> 2763
      <211> 476
      <212> PRT
      <213> Homo sapiens


      <400> 2763
 Met Val Asn Pro Thr Val Phe Phe Asp Thr Glu Pro Leu Gly Arg Ile
   1               5                  10                  15    
 Ser Phe Glu Leu Phe Ala Asp Lys Phe Pro Lys Thr Ala Gly Asn Phe
              20                  25                  30        
 His Ala Leu Ser Thr Gly Glu Lys Gly Phe Gly Tyr Lys Gly Ser Cys
          35                  40                  45            
 Phe His Arg Ile Val Pro Gly Phe Met Cys Gln Gly Gly Asp Phe Thr
      50                  55                  60                
 Cys His Asp Gly Thr Gly Gly Lys Ser Ile Tyr Arg Glu Lys Phe Asp
  65                  70                  75                  80
 Asp Lys Asn Phe Ile Arg Lys His Thr Val Ser Gly Ile Leu Ser Met
                  85                  90                  95    
 Ala Asn Ala Gly Pro Asn Ala Asn Ser Ser Gln Phe Phe Ile Cys Ala
             100                 105                 110        
 Ala Lys Thr Glu Trp Leu Asp Gly Lys His Val Val Phe Ser Lys Val
         115                 120                 125            
 Lys Glu Gly Met Asn Ile Val Glu Thr Met Glu Cys Phe Gly Ser Arg
     130                 135                 140                
 Asn Gly Lys Thr Lys Gly Ala Gly Leu Ala Gly Ser His Ser Gln Arg
 145                 150                 155                 160
 Trp Leu Ala Ala Ser Val Cys Gly Ala Ser Gln Pro Ser Arg Leu Leu
                 165                 170                 175    
 Ser Thr Ala Cys Arg Gln Gln Lys Leu Gln Ile Ser Gly Arg Ser Lys
             180                 185                 190        
 Gly Cys Ser Arg Lys Thr Ser Gly Leu Glu Asp Gln Gly Leu Thr Lys
         195                 200                 205            
 Asp Gly Thr Asn Asn Thr Gln Gly Ile Lys Leu Gln Leu Gly Glu Glu
     210                 215                 220                
 Glu Glu His Ser Pro Arg Pro Ser Ser Leu Val Pro Val Ser Gln Leu
 225                 230                 235                 240
 Lys Ala Asn Gly Ser Ser Ser Ala Ser Ile Ala Cys Ala Glu Asp Gly
                 245                 250                 255    
 Pro Ala Arg Pro Val Pro Gly Cys Gln Cys Gln Asn Gln Gly His His
             260                 265                 270        
 Gln Asn Lys Arg Pro Arg Thr Ser Gln Leu Cys Gln Met Pro Lys Thr
         275                 280                 285            
 His Leu Val Val Ala Asp Ala Arg Pro Asn Ile Ser Arg Val Phe Phe
     290                 295                 300                
 Gly Leu Pro Glu Arg Glu Ser Ala Leu Trp Ser Phe Pro Arg Asp Trp
 305                 310                 315                 320
 Leu Val Asn Leu Leu Asn Gln Cys Asp Glu Leu Gly Ile Arg Asn Gln
                 325                 330                 335    
 Phe Glu Val Glu Val Leu Ser Tyr Gly His Leu Pro Leu Ala Tyr Ser
             340                 345                 350        
 Ala Arg Cys Phe Thr Ala Arg Ser Glu Asp Arg Pro Lys Asp Glu Cys
         355                 360                 365            
 Glu Thr Cys Cys Ile Lys Tyr Pro Asn Gly Arg Asn Val Leu Ser Gln
     370                 375                 380                
 Glu Asn Gln Gln Val Phe Val Leu Asn Gly Ile Gln Thr Met Ser Gly
 385                 390                 395                 400
 Tyr Val Tyr Asn Leu Gly Asn Glu Leu Ala Ser Met Gln Gly Leu Val
                 405                 410                 415    
 Asp Val Val Arg Leu Ser Pro Gln Gly Thr Asp Thr Phe Ala Met Leu
             420                 425                 430        
 Asp Ala Phe Arg Ala Asn Glu Asn Gly Ala Ala Pro Leu Pro Leu Thr
         435                 440                 445            
 Ala Asn Ser Asp Cys Asn Gly Tyr Trp Arg Arg Leu Ala Asp Phe Glu
     450                 455                 460                
 Cys Thr Trp Ala His Ser Gln Gly Gly Cys His Ala
 465                 470                 475    



      <210> 2764
      <211> 781
      <212> PRT
      <213> Homo sapiens


      <400> 2764
 Met Thr Cys Gly Thr Asp Gly Ala Ile Thr Phe Trp Glu Ser Leu Thr
   1               5                  10                  15    
 Gly His Arg Tyr Ile His Lys Pro Thr Asn Pro Asp Glu Pro Pro Val
              20                  25                  30        
 Ala Glu Gln Pro Lys Pro Leu Tyr Pro Tyr Arg Thr Ile Gly Cys Val
          35                  40                  45            
 Phe Asn His Gln Met Phe Leu Gly Asn Cys Gln Pro Ser Asp Ala Val
      50                  55                  60                
 Glu Thr Cys Val Phe Asp Leu Asn Asp Glu Ser Lys Trp Lys Pro Met
  65                  70                  75                  80
 Ser Glu Glu Ala Ile Lys Ser Val Cys Ala Pro Gly Ala Thr Thr Ser
                  85                  90                  95    
 Leu Pro Pro Phe Pro Pro Leu Cys Ala Ser Thr Ile Asp Ala Ser Val
             100                 105                 110        
 Thr Ser Asn Glu Ile Glu Met Gln Leu Arg Leu Leu Val Ser Glu His
         115                 120                 125            
 Arg Lys Tyr Thr Lys Ile His Thr Cys Pro Ser Pro Thr Gly Gly Pro
     130                 135                 140                
 Val Glu Pro Ala Asp Thr Lys Ser Gln Pro Ser Val Cys Met Asp Phe
 145                 150                 155                 160
 Thr Ser His Glu Tyr Arg Ile Ser Asp Pro Phe Leu Val Glu Lys Asn
                 165                 170                 175    
 Leu Pro Lys Glu Lys Thr Ala Asn Thr Ala Gly His Gln Lys Glu Gln
             180                 185                 190        
 Thr Gly Asp Thr Leu Pro Leu Arg Asn Ile Thr Gly Thr Val Arg Val
         195                 200                 205            
 His Gly Phe Ile Leu Glu Val Ser Glu Thr Lys Asn Pro Pro Asn Pro
     210                 215                 220                
 Gly His Lys Thr Thr Ser Ile Ser Gln Arg Pro Lys Ala Leu Val Ser
 225                 230                 235                 240
 Leu Gly Pro Glu Val Arg Arg Gly Thr Arg Gly Glu Asp Glu Lys Ala
                 245                 250                 255    
 Leu Glu Lys Glu Gly Gly Gly Arg Arg Trp Glu Cys Gly Gly Ala Asn
             260                 265                 270        
 Glu Leu Cys Gly Arg Pro Pro Ala Phe Thr Arg Val Thr Val His Trp
         275                 280                 285            
 Gly Lys Gly Asn Asp Gln Thr Phe Gln Asp Leu Leu Asp Thr Gly Ser
     290                 295                 300                
 Glu Leu Thr Leu Ile Pro Gly Asp Pro Lys Arg His Cys Gly Pro Pro
 305                 310                 315                 320
 Val Lys Ile Gly Ala Tyr Gly Gly Gln Ile Ile Asn Gly Val Leu Ala
                 325                 330                 335    
 Gln Val Gln Leu Thr Val Asp Ala Val Gly Pro Trp Thr His Pro Val
             340                 345                 350        
 Val Phe Pro Ser Ala Arg Met His Asn Trp Asn Arg His Thr Gln Gln
         355                 360                 365            
 Leu Ala Glu Ser His Ile Gly Ser Leu Thr Val His Leu Ser Ser Asp
     370                 375                 380                
 Pro Lys Gly Cys His Ser Glu Trp Gly Pro Glu Gln Glu Lys Ala Leu
 385                 390                 395                 400
 Gln Glu Val Gln Ala Ala Val Gln Ala Ala Leu Ile Leu Glu Pro Tyr
                 405                 410                 415    
 Asp Pro Ala Gly Pro Val Val Leu Glu Val Ser Leu Ala Asp Arg Asp
             420                 425                 430        
 Ala Val Trp Ser Leu Trp Gln Ala Pro Ile Gly Glu Ser Gln Gln Arg
         435                 440                 445            
 Pro Leu Gly Phe Trp Ser Lys Ala Leu Pro Ser Ser Ala Ala Ile Lys
     450                 455                 460                
 Arg Val Met His Ser Ser Ile Pro Ser Ser Asn Gly Ser Gly Ile Tyr
 465                 470                 475                 480
 Met Ile Gly Leu Glu Gln Val Arg Lys Ala Gln Ile Val Leu His Asp
                 485                 490                 495    
 Met Gln Pro Pro Cys Glu Asn Gly Thr Ala Ser Ala Leu Gln Pro Leu
             500                 505                 510        
 Ser Arg Lys Ser Leu Lys Asp Ser Ser Glu Gly Lys Ser Ser Gln Trp
         515                 520                 525            
 Ala Glu Leu Arg Ala Val His Leu Ala Val His Val Ala Trp Lys Glu
     530                 535                 540                
 Lys Trp Pro Asp Val Arg Leu Asp Thr Asp Ser Trp Ala Val Ala Asn
 545                 550                 555                 560
 Gly Leu Ala Arg Trp Ser Gly Thr Trp Lys Glu His Asp Arg Lys Ile
                 565                 570                 575    
 Gly Asp Lys Glu Val Trp Gly Arg Gly Thr Arg Ile Glu Leu Ser Glu
             580                 585                 590        
 Trp Ser Lys Thr Val Thr Ile Phe Val Ser His Cys Phe Tyr Gln Asp
         595                 600                 605            
 Tyr His Pro Ser Val Gly Ser Gln Asn Ala Leu Tyr Thr Asn Met Val
     610                 615                 620                
 Phe His Thr Ala Leu Pro Leu Thr Lys Ala Leu Thr Leu Arg Leu Lys
 625                 630                 635                 640
 Asn Cys Asn Ser Gly Leu Met Leu Thr Glu Phe Thr Gly Leu Thr Met
                 645                 650                 655    
 Phe Pro Ile Ile Gln Gly Trp Gly Lys Val Leu Gln Lys Ala Val Tyr
             660                 665                 670        
 Ala Leu Asn Gln Arg Pro Ile Tyr Glu Trp Lys Glu Glu Ser Cys Leu
         675                 680                 685            
 His Thr Gly Val Ala Asp Ala Leu Arg Gly Asn Trp Ala Glu Gly His
     690                 695                 700                
 Arg Glu His Lys Ala Leu Trp Leu Gly Leu Trp Ser Thr Trp Ser Gln
 705                 710                 715                 720
 His Pro Leu Arg Ser Leu Lys Thr Thr Arg His His Pro Gly Leu Gly
                 725                 730                 735    
 Val Leu Ser Glu Asp Ile Cys Glu Ala Gly Gly Ala Thr Glu Glu Leu
             740                 745                 750        
 Ser Arg Ala Ser Gly Phe Ala Thr Gly Tyr Gly Lys Arg Lys Glu Asp
         755                 760                 765            
 Thr Lys Lys His Lys Gln His Ser Val Ser Asp Ile Met
     770                 775                 780    



      <210> 2765
      <211> 220
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(220)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2765
 Thr Arg Ile Ala Glu Thr Ile Leu Lys Lys Lys Thr Lys Val Gly Gly
   1               5                  10                  15    
 Thr Ile Leu Ser Asp Phe Lys Met Asn Lys Ala Arg Val Leu Glu Ile
              20                  25                  30        
 Val Trp Tyr Leu Trp Ser Asn Arg Cys Met Asn Gln Trp Asn Arg Ile
          35                  40                  45            
 Glu Asp Pro Glu Thr Asp Pro Gln Thr Asn Gly Ala Leu Ala Ile Gly
      50                  55                  60                
 His Pro Gln Thr Lys Gln Ile Lys Leu Thr Asn Arg Pro Gln Ser Leu
  65                  70                  75                  80
 Asn Leu Asn Leu Arg Pro Asp Met Lys Met Asn Ser Lys Trp Ile Val
                  85                  90                  95    
 Asp Leu Asn Val Lys Cys Glu Ala Ile Lys Thr Phe Glu Lys Lys Thr
             100                 105                 110        
 Arg Glu Asn Leu His His Gln Lys His Asn Leu Glu Asp Asn Ile Tyr
         115                 120                 125            
 Lys Leu Asn Phe Lys Ile Cys Ser Ala Lys Ser Ala Val Ser Arg Ile
     130                 135                 140                
 Lys Lys Lys Pro Thr Ala Xaa Glu Lys Ile Phe Ala Asn Arg Leu Ser
 145                 150                 155                 160
 Asn Ile Gly Leu Ile Ser Arg Glu Tyr Lys Gln Leu Leu Lys Leu Ser
                 165                 170                 175    
 Ser Xaa Lys Thr Val Xaa Leu Glu Asn Gly Gly Leu Ala Trp Trp Leu
             180                 185                 190        
 Thr Pro Val Ile Pro Ser Leu Arg Glu Ala Lys Val Asp Glu Pro Leu
         195                 200                 205            
 Glu Ala Arg Gly Ser Arg Pro Ala Tyr Pro Thr Trp
     210                 215                 220



      <210> 2766
      <211> 64
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(64)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2766
 Ser Val Ala His Ser Ser Cys Val Ser His Thr His Met His Thr Leu
   1               5                  10                  15    
 Leu Gly Arg Arg Ala Thr Ile Asn Cys Leu Phe Arg Asn Gly Arg Gly
              20                  25                  30        
 Gln Val Gln Trp Leu Thr Ser Ala Val Pro Ala Leu Arg Lys Ala Asp
          35                  40                  45            
 Val Gly Gly Xaa Leu Glu Pro Arg Ser Ser Arg Pro Ala Trp Ala Thr
      50                  55                  60                





      <210> 2767
      <211> 64
      <212> PRT
      <213> Homo sapiens


      <400> 2767
 Met Val Met Leu Thr Leu Ala Ile Arg Leu Met Gln Phe Glu Phe Arg
   1               5                  10                  15    
 Gln Phe Phe Ile Lys Val Asn Phe Arg Met Arg Gly Leu Ser Lys Met
              20                  25                  30        
 Ala Met Leu Leu Leu Cys Arg Ala Arg Pro Tyr Ser Tyr Lys Lys Glu
          35                  40                  45            
 Glu Gly Trp Ser Val Leu Ser Gly Tyr Phe Leu Thr Ala Gly Asn Phe
      50                  55                  60                





      <210> 2768
      <211> 119
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(119)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2768
 Asp Phe Tyr Leu Tyr Pro Glu Arg Lys Lys Arg Gly Gln Met Met Thr
   1               5                  10                  15    
 Ala Val Ser Leu Thr Thr Arg Pro Gln Glu Ser Val Ala Phe Glu Asp
              20                  25                  30        
 Val Ala Val Tyr Phe Thr Thr Lys Glu Trp Ala Ile Met Gly Pro Ala
          35                  40                  45            
 Glu Arg Ala Leu Tyr Arg Asp Val Met Leu Glu Asn Tyr Gly Gly Cys
      50                  55                  60                
 Gly Pro Leu Xaa Cys His Pro Thr Ser Lys Pro Ala Leu Val Phe Ser
  65                  70                  75                  80
 Leu Glu Gln Gly Lys Glu Ser Cys Phe Ser Pro Ala Thr Gly Ser Ser
                  85                  90                  95    
 Leu Ser Arg Asn Asp Trp Arg Ala Gly Trp Ile Gly Tyr Leu Glu Leu
             100                 105                 110        
 Arg Arg Tyr Thr Tyr Leu Ser
         115                



      <210> 2769
      <211> 1600
      <212> PRT
      <213> Homo sapiens


      <400> 2769
 Lys Arg Leu Glu Asn Ile Gln Lys Thr Leu Glu Val Ala Phe Ser Glu
   1               5                  10                  15    
 Ala Val Trp Met Gln Pro Ser Val Val Leu Leu Asp Asp Leu Asp Leu
              20                  25                  30        
 Ile Ala Gly Leu Pro Ala Val Pro Glu His Glu His Ser Pro Asp Ala
          35                  40                  45            
 Val Gln Ser Gln Arg Leu Ala His Ala Leu Asn Asp Met Ile Lys Glu
      50                  55                  60                
 Phe Ile Ser Met Gly Ser Leu Val Ala Leu Ile Ala Thr Ser Gln Ser
  65                  70                  75                  80
 Gln Gln Ser Leu His Pro Leu Leu Val Ser Ala Gln Gly Val His Ile
                  85                  90                  95    
 Phe Gln Cys Val Gln His Ile Gln Pro Pro Asn Gln Glu Gln Arg Cys
             100                 105                 110        
 Glu Ile Leu Cys Asn Val Ile Lys Asn Lys Leu Asp Cys Asp Ile Asn
         115                 120                 125            
 Lys Phe Thr Asp Leu Asp Leu Gln His Val Ala Lys Glu Thr Gly Gly
     130                 135                 140                
 Phe Val Ala Arg Asp Phe Thr Val Leu Val Asp Arg Ala Ile His Ser
 145                 150                 155                 160
 Arg Leu Ser Arg Gln Ser Ile Ser Thr Arg Glu Lys Leu Val Leu Thr
                 165                 170                 175    
 Thr Leu Asp Phe Gln Lys Ala Leu Arg Gly Phe Leu Pro Ala Ser Leu
             180                 185                 190        
 Arg Ser Val Asn Leu His Lys Pro Arg Asp Leu Gly Trp Asp Lys Ile
         195                 200                 205            
 Gly Gly Leu His Glu Val Arg Gln Ile Leu Met Asp Thr Ile Gln Leu
     210                 215                 220                
 Pro Ala Lys Tyr Pro Glu Leu Phe Ala Asn Leu Pro Ile Arg Gln Arg
 225                 230                 235                 240
 Thr Gly Ile Leu Leu Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Leu
                 245                 250                 255    
 Ala Gly Val Ile Ala Arg Glu Ser Arg Met Asn Phe Ile Ser Val Lys
             260                 265                 270        
 Gly Pro Glu Leu Leu Ser Lys Tyr Ile Gly Ala Ser Glu Gln Ala Val
         275                 280                 285            
 Arg Asp Ile Phe Ile Arg Ala Gln Ala Ala Lys Pro Cys Ile Leu Phe
     290                 295                 300                
 Phe Asp Glu Phe Glu Ser Ile Ala Pro Arg Arg Gly His Asp Asn Thr
 305                 310                 315                 320
 Gly Val Thr Asp Arg Val Val Asn Gln Leu Leu Thr Gln Leu Asp Gly
                 325                 330                 335    
 Val Glu Gly Leu Gln Gly Val Tyr Val Leu Ala Ala Thr Ser Arg Pro
             340                 345                 350        
 Asp Leu Ile Asp Pro Ala Leu Leu Arg Pro Gly Arg Leu Asp Lys Cys
         355                 360                 365            
 Val Tyr Cys Pro Pro Pro Asp Gln Asp Gly Ser Ser Ser Ser Asp Ser
     370                 375                 380                
 Asp Leu Ser Leu Ser Ser Met Val Phe Leu Asn His Ser Ser Gly Ser
 385                 390                 395                 400
 Asp Asp Ser Ala Gly Asp Gly Glu Cys Gly Leu Asp Gln Ser Leu Val
                 405                 410                 415    
 Ser Leu Glu Met Ser Glu Ile Leu Pro Asp Glu Ser Lys Phe Asn Met
             420                 425                 430        
 Tyr Arg Leu Tyr Phe Gly Ser Ser Tyr Glu Ser Glu Leu Gly Asn Gly
         435                 440                 445            
 Thr Ser Ser Asp Leu Glu Asp Glu Ser Met Asn Gln Pro Gly Pro Ile
     450                 455                 460                
 Lys Thr Arg Leu Ala Ile Ser Gln Ser His Leu Met Thr Ala Leu Gly
 465                 470                 475                 480
 His Thr Arg Pro Ser Ile Ser Glu Asp Asp Trp Lys Asn Phe Ala Glu
                 485                 490                 495    
 Leu Tyr Glu Ser Phe Gln Asn Pro Lys Arg Arg Lys Asn Gln Ser Gly
             500                 505                 510        
 Thr Met Phe Arg Pro Gly Gln Lys Phe Phe Asp Glu Ile Thr Glu Leu
         515                 520                 525            
 Thr Tyr Leu Pro Ser Phe His His Lys Ala Ala Pro His Gln Ala Glu
     530                 535                 540                
 Pro Gly Pro Asn Ser Ser Ser Ala Ser Ala Pro Pro Pro Tyr Asn Pro
 545                 550                 555                 560
 Phe Ile Thr Ser Ser Pro His Thr Gln Ser Gly Leu Gln Phe Arg Ser
                 565                 570                 575    
 Val Thr Ser Pro Pro Pro Ser Ala Gln Gln Phe Pro Leu Lys Glu Val
             580                 585                 590        
 Ala Gly Ala Lys Gly Ile Val Lys Thr Ala Leu Glu Thr Ala Pro Thr
         595                 600                 605            
 Leu Ala Leu Pro Val Ser Ser Gln Pro Phe Ser Leu His Thr Ala Glu
     610                 615                 620                
 Val Gln Gly Cys Ala Val Gly Ile Leu Thr Gln Gly Pro Gly Pro Cys
 625                 630                 635                 640
 Pro Val Ala Phe Leu Ser Lys Gln Leu Asp Leu Thr Val Leu Gly Ser
                 645                 650                 655    
 Pro Ser Cys Leu His Ala Val Ala Ser Ala Ala Leu Ile Leu Leu Glu
             660                 665                 670        
 Ala Leu Lys Ile Thr Asn Tyr Ala Gln Leu Thr Leu Tyr Ser Ser His
         675                 680                 685            
 Asn Phe Gln Asn Leu Phe Ser Phe Ser His Leu Thr His Ile Leu Ser
     690                 695                 700                
 Ala Pro Arg Leu Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Pro Thr
 705                 710                 715                 720
 Ile Thr Ile Leu Pro Gly Pro Asp Phe Asn Leu Ala Ser His Ile Ile
                 725                 730                 735    
 Leu Asp Thr Thr Pro Asp Pro Asp Asp Cys Met Ser Leu Ile Tyr Leu
             740                 745                 750        
 Thr Phe Thr Pro Phe Pro His Ile Ser Phe Phe Ser Val Pro His Val
         755                 760                 765            
 Asp His Ile Trp Phe Thr Asp Gly Ser Ser Thr Arg Pro Asp Arg His
     770                 775                 780                
 Ser Pro Ala Lys Ala Gly Tyr Ala Ile Glu Ser Ser Thr Ser Ile Ile
 785                 790                 795                 800
 Glu Ala Thr Ala Leu Pro Pro Ser Thr Thr Ser Gln Gln Ala Glu Leu
                 805                 810                 815    
 Ile Ala Leu Thr Arg Ala Phe Thr Leu Ala Lys Gly Leu His Val Asn
             820                 825                 830        
 Ile Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Leu His His His Ala
         835                 840                 845            
 Val Ile Trp Ala Glu Arg Gly Phe Leu Thr Thr Gln Gly Ser Ser Ile
     850                 855                 860                
 Ile Asn Ala Ser Leu Ile Lys Thr Leu Leu Lys Ala Ala Leu Leu Pro
 865                 870                 875                 880
 Lys Glu Ala Gly Val Thr His Cys Lys Gly His Gln Lys Ala Ser Asp
                 885                 890                 895    
 Pro Ile Thr Leu Gly Asn Ala Tyr Ala Asp Lys Asp Arg Thr Ile Asp
             900                 905                 910        
 Gly Ser Ser Gln Val Ile Glu Glu Lys Asn His Asn Gly Tyr Ser Val
         915                 920                 925            
 Ile Asp Thr Gly Thr Leu Val Glu Ala Glu Leu Glu Lys Leu Pro Asn
     930                 935                 940                
 Asn Trp Ser Pro Gln Thr Cys Glu Leu Phe Ala Leu Ser Gln Ala Leu
 945                 950                 955                 960
 Lys Tyr Leu Gln Asn Gln Lys Thr Ile Ser Ile Leu Ile Gln Lys Glu
                 965                 970                 975    
 Pro Ser Pro Ala Leu Gly Leu Thr Pro Glu Arg Lys Gly Asn Val Gly
             980                 985                 990        
 His Ala Gly Lys Gly Pro Leu Glu Ser Ser Ser Pro Asp Pro Phe Leu
         995                1000                1005            
 Cys Gly Gln Glu Arg Arg Glu Lys Gly Cys Arg Thr Ala Thr Ser Val
    1010                1015                1020                
 Ser Ile Thr Asn Pro Ile Asn Arg Gly Pro Trp Val Val Thr His Pro
1025                1030                1035                1040
 Gly Lys Glu Leu Thr Pro Glu His Lys Gly Asn Val Gly His Ala Gly
                1045                1050                1055    
 Arg Asp Ile Leu Ala Lys Ala Gly Ala Ile Ile His Leu Asn Ile Gly
            1060                1065                1070        
 Glu Gly Thr Pro Val Cys Cys Pro Leu Leu Glu Glu Gly Ile Asn Pro
        1075                1080                1085            
 Glu Val Trp Ala Thr Glu Gly Gln Tyr Gly Arg Ala Lys Asn Ala Arg
    1090                1095                1100                
 Pro Val Gln Val Lys Leu Lys Asp Ser Thr Ser Phe Pro Tyr Gln Arg
1105                1110                1115                1120
 Gln Tyr Pro Leu Arg Pro Lys Ala Gln Gln Gly Leu Gln Lys Ile Val
                1125                1130                1135    
 Lys Asp Leu Lys Ala Gln Gly Leu Val Lys Pro Cys Ser Asn Pro Cys
            1140                1145                1150        
 Ser Thr Pro Ile Leu Gly Val Gln Lys Pro Asn Arg Gln Trp Arg Thr
        1155                1160                1165            
 Leu Cys His Gln Ala Thr Gln Ala Leu Phe Asn Phe Leu Ala Thr Cys
    1170                1175                1180                
 Gly Tyr Met Val Ser Lys Pro Lys Ala Gln Leu Cys Ser Gln Gln Arg
1185                1190                1195                1200
 Tyr Leu Gly Leu Lys Leu Ser Lys Gly Thr Arg Ala Leu Ser Glu Glu
                1205                1210                1215    
 His Ile Gln Pro Ile Leu Ala Tyr Pro His Pro Lys Thr Leu Lys Gln
            1220                1225                1230        
 Leu Arg Gly Phe Leu Gly Val Ile Gly Phe Cys Arg Lys Trp Ile Pro
        1235                1240                1245            
 Arg Tyr Gly Glu Ile Ala Arg Ser Leu Asn Thr Leu Ile Lys Glu Thr
    1250                1255                1260                
 Gln Lys Ala Asn Thr His Leu Val Arg Trp Thr Thr Glu Val Glu Val
1265                1270                1275                1280
 Ala Phe Gln Ala Leu Thr Gln Ala Pro Val Leu Ser Leu Pro Thr Gly
                1285                1290                1295    
 Gln Asp Phe Ser Ser Tyr Val Thr Glu Lys Thr Gly Ile Ala Leu Gly
            1300                1305                1310        
 Val Leu Thr Gln Ile Arg Gly Met Ser Leu Gln Pro Val Ala Tyr Leu
        1315                1320                1325            
 Thr Lys Glu Ile Asp Val Val Ala Lys Val Val Ala Val Ala Val Leu
    1330                1335                1340                
 Val Ser Glu Ala Val Lys Ile Ile Gln Gly Arg Asp Leu Thr Val Trp
1345                1350                1355                1360
 Thr Ser His Asp Val Asn Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp
                1365                1370                1375    
 Leu Ser Asp Asn Cys Leu Leu Lys Cys Gln Ala Leu Leu Leu Glu Gly
            1380                1385                1390        
 Pro Val Leu Arg Leu Cys Thr Cys Ala Thr Leu Asn Pro Ala Thr Phe
        1395                1400                1405            
 Leu Pro Asp Asn Glu Glu Lys Ile Lys His Asn Cys Gln Gln Val Ile
    1410                1415                1420                
 Ser Gln Thr Tyr Ala Thr Arg Gly Asp Leu Leu Glu Val Pro Leu Thr
1425                1430                1435                1440
 Asp Pro Asp Leu Asn Leu Tyr Thr Asp Gly Ser Ser Phe Val Glu Lys
                1445                1450                1455    
 Gly Leu Arg Lys Val Gly Tyr Ala Val Val Ser Asp Asn Gly Ile Leu
            1460                1465                1470        
 Glu Ser Asn Pro Leu Thr Pro Gly Thr Ser Ala Gln Leu Ala Glu Leu
        1475                1480                1485            
 Ile Ala Leu Thr Trp Ala Leu Glu Leu Gly Glu Glu Lys Arg Ala Asn
    1490                1495                1500                
 Ile Tyr Thr Asp Ser Lys Tyr Ala Tyr Leu Val Leu His Ala His Ala
1505                1510                1515                1520
 Ala Ile Trp Lys Glu Arg Glu Phe Leu Thr Ser Glu Arg Thr Pro Ile
                1525                1530                1535    
 Lys His Gln Glu Ala Ile Arg Lys Leu Leu Leu Ala Val Gln Lys Pro
            1540                1545                1550        
 Lys Glu Val Ala Val Leu His Cys Arg Gly His Gln Lys Gly Lys Glu
        1555                1560                1565            
 Arg Glu Ile Glu Glu Asn Cys Gln Ala Asp Ile Glu Ala Lys Arg Ala
    1570                1575                1580                
 Ala Arg Gln Asp Pro Pro Leu Glu Met Leu Ile Lys Gln Pro Leu Val
1585                1590                1595                1600





      <210> 2770
      <211> 973
      <212> PRT
      <213> Homo sapiens


      <400> 2770
 Met Leu Leu Ala Thr Ala Leu Arg Gly Phe Leu Lys Asn Gly Asp Arg
   1               5                  10                  15    
 Gly His Val Asp Thr Glu Glu Trp Arg Ser Tyr Pro Trp Ala Ala Ser
              20                  25                  30        
 Phe Gly Gln Leu Arg Ser Ser Gln Asn Cys Pro Gly Ala Ser Ala Ser
          35                  40                  45            
 Gly Arg Thr Gly Val Pro Thr Val Leu Val Ala Arg Thr Asp Ala Asp
      50                  55                  60                
 Ala Ser Asp Leu Ile Thr Ser Asp Cys Asp Pro Tyr Asp Ser Glu Phe
  65                  70                  75                  80
 Met Thr Gly Glu Arg Thr Ser Glu Gly Phe Phe Arg Thr His Ala Gly
                  85                  90                  95    
 Ile Glu Gln Ala Ile Ser Arg Gly Leu Ala Tyr Ala Pro Tyr Ala Asp
             100                 105                 110        
 Leu Val Trp Cys Glu Thr Ser Thr Pro Asp Leu Glu Leu Ala Arg Arg
         115                 120                 125            
 Phe Ala Gln Ala Ile His Ala Lys Tyr Pro Gly Lys Leu Leu Ala Tyr
     130                 135                 140                
 Asn Cys Ser Pro Ser Phe Asn Trp Gln Lys Asn Leu Asp Asp Lys Thr
 145                 150                 155                 160
 Ile Ala Ser Phe Gln Gln Gln Leu Ser Asp Met Gly Tyr Lys Phe Gln
                 165                 170                 175    
 Phe Ile Thr Leu Ala Gly Ile His Ser Met Trp Phe Asn Met Phe Asp
             180                 185                 190        
 Leu Ala Asn Ala Tyr Ala Gln Gly Glu Gly Met Lys His Tyr Val Glu
         195                 200                 205            
 Lys Val Gln Gln Pro Glu Phe Ala Ala Ala Lys Asp Gly Tyr Thr Phe
     210                 215                 220                
 Val Ser His Gln Gln Glu Val Gly Thr Gly Tyr Phe Asp Lys Val Thr
 225                 230                 235                 240
 Thr Ile Ile Gln Gly Gly Thr Pro Asp Lys Ala Phe Thr Pro His Pro
                 245                 250                 255    
 Ala Ser Lys Pro Ala His Lys Pro Gly Glu Gln Pro Met Lys Asn Asn
             260                 265                 270        
 Pro Leu Ile Ser Ile Tyr Met Pro Thr Trp Asn Arg Gln Gln Leu Ala
         275                 280                 285            
 Ile Arg Ala Ile Lys Ser Val Leu Arg Gln Asp Tyr Ser Asn Trp Glu
     290                 295                 300                
 Met Ile Ile Val Asp Asp Cys Ser Thr Ser Trp Glu Gln Leu Gln Gln
 305                 310                 315                 320
 Tyr Val Thr Ala Leu Asn Asp Pro Arg Ile Thr Tyr Ile His Asn Asp
                 325                 330                 335    
 Ile Asn Ser Gly Ala Cys Ala Val Arg Asn Gln Ala Ile Met Leu Ala
             340                 345                 350        
 Gln Gly Glu Tyr Ile Thr Gly Ile Asp Asp Asp Asp Glu Trp Thr Pro
         355                 360                 365            
 Asn Arg Leu Ser Val Phe Leu Ala His Lys Gln Gln Leu Val Thr His
     370                 375                 380                
 Ala Phe Leu Tyr Ala Asn Asp Tyr Val Cys Gln Gly Glu Val Tyr Ser
 385                 390                 395                 400
 Gln Pro Ala Ser Leu Pro Leu Tyr Pro Lys Ser Pro Tyr Ser Arg Arg
                 405                 410                 415    
 Leu Phe Tyr Lys Arg Asn Ile Ile Gly Asn Gln Val Phe Thr Trp Ala
             420                 425                 430        
 Trp Arg Phe Lys Glu Cys Leu Phe Asp Thr Glu Leu Lys Ala Ala Gln
         435                 440                 445            
 Asp Tyr Asp Ile Phe Leu Arg Met Val Val Glu Tyr Gly Glu Pro Trp
     450                 455                 460                
 Lys Val Glu Glu Ala Thr Gln Ile Leu Ala Ile Asn His Gly Glu Met
 465                 470                 475                 480
 Pro Ile His Ser Ser Arg Glu His Phe Arg Val Leu Pro Phe Cys Arg
                 485                 490                 495    
 Ser Thr Arg Pro Phe Arg Gln Ala Arg Lys Ile Ser Arg Val Ile Val
             500                 505                 510        
 Thr Ser Thr Lys Ser Asp Ser Leu Tyr Thr Val Gly Met Leu Ala Leu
         515                 520                 525            
 Ser Val Arg Ala Ile Arg Cys Pro Leu Tyr Leu Leu Thr Gly Leu Ile
     530                 535                 540                
 Ser Val Ser Lys Asn Gly Leu Trp Tyr Cys Glu Leu Gln Val Ala Leu
 545                 550                 555                 560
 His Gly Arg Ser Val Thr Leu Tyr Glu Lys Ala Phe Pro Leu Ser Glu
                 565                 570                 575    
 Gln Cys Ser Lys Lys Ala His Asp Gln Phe Leu Ala Asp Leu Ala Ser
             580                 585                 590        
 Ile Leu Pro Ser Asn Thr Thr Pro Leu Ile Val Ser Asp Ala Gly Phe
         595                 600                 605            
 Lys Val Pro Trp Tyr Lys Ser Val Glu Lys Leu Gly Trp Tyr Trp Leu
     610                 615                 620                
 Ser Arg Arg Met Gln Ile Glu Glu Thr Phe Arg Asp Leu Lys Ser Pro
 625                 630                 635                 640
 Ala Tyr Gly Leu Gly Leu Arg His Ser Arg Thr Ser Ser Ser Glu Arg
                 645                 650                 655    
 Phe Asp Ile Met Leu Leu Ile Ala Leu Met Leu Gln Leu Thr Cys Trp
             660                 665                 670        
 Leu Ala Gly Val His Ala Gln Lys Gln Gly Leu Asp Leu Gly Val Tyr
         675                 680                 685            
 Gly Ala Pro Glu Thr Phe Leu Ile Asp Gly Asn Gly Ile Ile Arg Tyr
     690                 695                 700                
 Arg His Ala Gly Asp Leu Asn Pro Arg Val Trp Glu Glu Glu Ile Lys
 705                 710                 715                 720
 Pro Leu Trp Glu Lys Tyr Thr Leu Ala Thr Ile Asp Val Leu Gln Phe
                 725                 730                 735    
 Lys Asp Glu Ala Gln Glu Gln Gln Phe Arg Gln Leu Thr Glu Glu Leu
             740                 745                 750        
 Arg Cys Pro Lys Cys Gln Asn Asn Ser Ile Ala Asp Ser Asn Ser Met
         755                 760                 765            
 Ile Ala Thr Asp Leu Arg Gln Lys Val Tyr Glu Leu Met Gln Glu Gly
     770                 775                 780                
 Lys Ser Lys Lys Glu Ile Val Asp Tyr Met Val Ala Arg Tyr Gly Asn
 785                 790                 795                 800
 Phe Val Thr Tyr Asp Pro Pro Leu Thr Pro Leu Thr Val Leu Leu Trp
                 805                 810                 815    
 Val Leu Pro Val Val Ala Ile Gly Ile Gly Gly Trp Val Ile Tyr Ala
             820                 825                 830        
 Arg Ser Arg Arg Arg Val Arg Val Val Pro Glu Ala Phe Pro Glu Gln
         835                 840                 845            
 Ser Val Pro Glu Gly Lys Arg Ala Gly Tyr Val Val Tyr Leu Pro Gly
     850                 855                 860                
 Ile Val Val Ala Leu Ile Val Ala Gly Val Ser Tyr Tyr Gln Thr Gly
 865                 870                 875                 880
 Asn Tyr Gln Gln Val Lys Ile Trp Gln Gln Ala Thr Ala Gln Ala Pro
                 885                 890                 895    
 Ala Leu Leu Asp Arg Ala Leu Asp Pro Lys Ala Asp Pro Leu Asn Glu
             900                 905                 910        
 Glu Glu Met Ser Arg Leu Ala Leu Gly Met Arg Thr Gln Leu Gln Lys
         915                 920                 925            
 Asn Pro Gly Asp Ile Glu Gly Trp Ile Met Leu Gly Arg Val Gly Met
     930                 935                 940                
 Ala Leu Gly Asn Ala Ser Ile Ala Thr Asp Cys Tyr Ala Thr Gly Tyr
 945                 950                 955                 960
 Arg Leu Asp Arg Thr Thr Val Met Leu Asp Gly Asp Arg
                 965                 970            



      <210> 2771
      <211> 590
      <212> PRT
      <213> Homo sapiens


      <400> 2771
 Met Ala Leu Gly Ile Ser Ala Pro Val Ala Leu Gln Gly Thr Ala Pro
   1               5                  10                  15    
 Leu Leu Ala Val Leu Ser Gly Cys Ser Phe Pro Lys His Met Leu Gln
              20                  25                  30        
 Thr Val Asn Gly Ser Pro Phe Trp Gly Leu Glu Asn Gly Gly Pro Leu
          35                  40                  45            
 Leu Arg Ala Arg Leu Gly Ser Ala Pro Val Glu Thr Leu Glu Leu Phe
      50                  55                  60                
 Ser Ser Leu Asn Lys Ile Leu His Ser Tyr His Ser Ser Val Val Lys
  65                  70                  75                  80
 Cys Asp Leu Ile Leu Leu Gly Arg Trp Thr Lys Ala Trp Asp Pro Leu
                  85                  90                  95    
 Ser Ala Gly Gly Gly Cys His Thr Gly Pro Leu Pro Leu Gln Val Glu
             100                 105                 110        
 Gly Asn His Pro Thr Gly Ser Tyr Arg Val Pro Asn Arg Pro Gln Tyr
         115                 120                 125            
 Arg Ser Val Ala Trp Gly Leu Gly Thr Ser Gly Leu Val Asn Tyr Thr
     130                 135                 140                
 Phe Leu Leu Asn Ser Gly Glu Thr Thr Tyr Gln Phe Leu Arg Gly Asn
 145                 150                 155                 160
 Lys Asp Phe Leu Lys Asn His Ile Lys Leu Asn Tyr Cys Phe Leu Leu
                 165                 170                 175    
 Ile Glu Val Asp Asn Leu Thr Leu Val Phe Val Ile Glu Lys Thr Leu
             180                 185                 190        
 Gly Gln Ile Phe Asp Ile Pro Lys Val Glu Leu Leu Phe Ser Tyr Gln
         195                 200                 205            
 Cys Phe Pro Met Val Glu Asn Arg Gln Lys Pro Glu Gly Glu Glu Asp
     210                 215                 220                
 Cys Val Ile Gln Leu Ser Glu Leu Ser Cys Thr Glu Cys Ser Lys Lys
 225                 230                 235                 240
 Ala Trp Arg Met Glu Val Leu His Thr Asn Lys Thr Thr Asn Ala Thr
                 245                 250                 255    
 Gln Cys Gly Gly Pro Ala Gln Leu Gln Gln Phe Asn Ala Val Leu Ser
             260                 265                 270        
 Glu Lys Val His Ile Val Pro Ser Leu Leu Arg Ser Trp Asn Ile Ile
         275                 280                 285            
 Ser His Gly Arg Phe Pro Ser Phe Glu Thr Phe Asn Thr Lys Asn Cys
     290                 295                 300                
 Ile Ala Tyr Asn Pro Asn Gly Asn Ala Leu Asp Glu Ser Cys Glu Asp
 305                 310                 315                 320
 Lys Asn Arg Tyr Ile Trp Leu Glu Lys Pro Gln Glu Thr Tyr Ser Asn
                 325                 330                 335    
 Asp Arg Arg Glu Ser Lys His Ile Pro Leu Arg Met Ala Ala Glu Arg
             340                 345                 350        
 Arg Arg Ala Glu Gln Lys Glu Lys Tyr Pro Leu Ile Lys Ser Ser Asp
         355                 360                 365            
 Leu Gly Ala Ser Glu Ala Ile Arg Gln Arg Gln Ser Ser Ala Ala Lys
     370                 375                 380                
 Leu Arg Lys Ser Gly Lys Glu Ser Val Arg Glu Pro Trp Ala Arg Val
 385                 390                 395                 400
 Pro Gly Ala Leu Gly Val Ala Ala Arg Ala Leu Ile Ala Glu Asp Ala
                 405                 410                 415    
 Gly Leu Ser Arg Val Ile Leu Phe His Tyr Gly Glu Ser Trp Asn Leu
             420                 425                 430        
 Leu Arg Ala Asp Gln Arg Leu Ile Phe Ala Lys Ser Trp Pro Arg Ala
         435                 440                 445            
 Ser Arg Tyr Gln Gln Gly His Gln Asp Leu Phe Ile Leu Arg Ser Asp
     450                 455                 460                
 Leu Pro Ser Gln Val Phe Ile Arg Asp Lys Leu Met Glu Arg Arg Asn
 465                 470                 475                 480
 Arg Arg Thr Gly Arg Thr Glu Lys Ala Arg Ile Trp Glu Val Thr Asp
                 485                 490                 495    
 Arg Thr Val Arg Thr Trp Ile Gly Glu Ala Val Ala Ala Ala Ala Ala
             500                 505                 510        
 Asp Gly Val Thr Phe Ser Val Pro Val Thr Pro His Thr Phe Arg His
         515                 520                 525            
 Ser Tyr Ala Met His Met Leu Tyr Ala Gly Ile Pro Leu Lys Val Leu
     530                 535                 540                
 Gln Ser Leu Met Gly His Lys Ser Ile Ser Ser Thr Glu Val Tyr Thr
 545                 550                 555                 560
 Lys Val Phe Ala Leu Asp Val Ala Ala Arg His Arg Val Gln Phe Ala
                 565                 570                 575    
 Met Pro Glu Ser Asp Ala Val Ala Met Leu Lys Gln Leu Ser
             580                 585                 590



      <210> 2772
      <211> 52
      <212> PRT
      <213> Homo sapiens


      <400> 2772
 Met Arg Pro Cys Cys Trp Trp Ala Thr Leu Cys Gly Lys His Leu Arg
   1               5                  10                  15    
 Met Cys Ser His Ala Leu Lys Met Arg Pro Asn Ala Ser Ala Ala Glu
              20                  25                  30        
 Thr Glu Gln Leu Asn Ala His Ser Arg Gly Leu Met Asn Ser Ser Ser
          35                  40                  45            
 Arg Pro Ala Pro
      50        



      <210> 2773
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 2773
 Gly Asn Arg Ala Gly Ala Leu Pro Gly Ala Thr Leu Leu Ile Leu Ala
   1               5                  10                  15    
 Gly Phe Leu Pro Ser Ala His Gln Asn Arg Pro Ser Arg Asn Pro Val
              20                  25                  30        
 Ser Arg Pro Pro Asn Thr Gln Arg Val Ala Arg Arg Lys His Tyr Ala
          35                  40                  45            
 Leu Ala Asp Gly Tyr Thr Glu Arg Arg Trp Thr Asn Ala Pro
      50                  55                  60        



      <210> 2774
      <211> 220
      <212> PRT
      <213> Homo sapiens


      <400> 2774
 Met Pro Asn Phe Phe Ile Asp Arg Pro Ile Phe Ala Trp Val Ile Ala
   1               5                  10                  15    
 Ile Ile Ile Met Leu Ala Gly Gly Leu Ala Ile Leu Lys Leu Pro Val
              20                  25                  30        
 Ala Gln Tyr Pro Thr Ile Ala Pro Pro Ala Val Thr Ile Ser Ala Ser
          35                  40                  45            
 Tyr Pro Gly Ala Asp Ala Lys Thr Val Gln Asp Thr Val Thr Gln Val
      50                  55                  60                
 Ile Glu Gln Asn Met Asn Gly Ile Asp Asn Leu Met Tyr Met Ser Ser
  65                  70                  75                  80
 Asn Ser Asp Ser Thr Gly Thr Val Gln Ile Thr Leu Thr Phe Glu Ser
                  85                  90                  95    
 Gly Gln Val Gln Asn Lys Leu Gln Leu Ala Met Pro Leu Leu Pro Gln
             100                 105                 110        
 Glu Val Gln Gln Gln Gly Val Ser Val Glu Lys Ser Ser Ser Ser Phe
         115                 120                 125            
 Leu Met Val Val Gly Val Ile Asn Thr Asp Gly Thr Met Thr Gln Glu
     130                 135                 140                
 Asp Ile Ser Asp Tyr Val Ala Ala Asn Met Lys Asp Ala Ile Ser Arg
 145                 150                 155                 160
 Thr Ser Gly Val Gly Asp Val Gln Leu Phe Gly Ser Gln Tyr Ala Met
                 165                 170                 175    
 Arg Ile Trp Met Asn Pro Asn Glu Leu Asn Lys Val Glu Arg Asn Ser
             180                 185                 190        
 Arg Arg Gln Asp Val Gly Glu Arg Asp Ile Ser Ser Gly Ser Arg Lys
         195                 200                 205            
 Val Asn Lys Glu Ser Arg Glu Asp Glu Glu Val Thr
     210                 215                 220



      <210> 2775
      <211> 62
      <212> PRT
      <213> Homo sapiens


      <400> 2775
 Pro Val Glu Arg Ser Asn Leu Gly Val Arg Leu Tyr Ala Cys Cys Gly
   1               5                  10                  15    
 Leu Leu Leu Arg Pro Ala Tyr Pro Gln His Phe Ala His Gly Tyr Val
              20                  25                  30        
 Asp Lys Ile Pro Asp Tyr Pro Arg Arg Ala Gly Thr Leu Thr Gly Leu
          35                  40                  45            
 His Pro Met Gln Val Cys Arg Cys Arg Arg Ala Arg Glu Leu
      50                  55                  60        



      <210> 2776
      <211> 306
      <212> PRT
      <213> Homo sapiens


      <400> 2776
 Met Leu Asp Asp Tyr Gly Gly Ser Leu Ser Glu Leu Ala Arg Glu Gln
   1               5                  10                  15    
 Leu Pro Ala Ala Glu Gln Ala Ala Leu Ala Gln Leu Ala Ala Arg Ser
              20                  25                  30        
 Leu Ala Pro Val Pro Asp Asp Thr Gly Gly Ala Gly Met Ser Asn Asp
          35                  40                  45            
 Thr Pro Phe Asp Ala Leu Trp Gln Arg Met Leu Ala Arg Gly Trp Thr
      50                  55                  60                
 Pro Val Ser Glu Ser Arg Leu Asp Asp Trp Leu Thr Gln Ala Pro Asp
  65                  70                  75                  80
 Gly Val Val Leu Leu Ser Ser Asp Pro Lys Arg Thr Pro Glu Val Ser
                  85                  90                  95    
 Asp Asn Pro Val Met Ile Gly Glu Leu Leu Arg Glu Phe Pro Asp Tyr
             100                 105                 110        
 Thr Trp Gln Val Ala Ile Ala Asp Leu Glu Gln Ser Gly Arg Ile Gly
         115                 120                 125            
 Asp Arg Phe Gly Val Phe Arg Phe Pro Ala Thr Leu Val Phe Thr Gly
     130                 135                 140                
 Gly Asn Tyr Arg Gly Val Leu Asn Gly Ile His Pro Leu Ala Glu Leu
 145                 150                 155                 160
 Ile Asn Leu Met Arg Trp Leu Val Glu Pro Gln Gln Glu Leu His Gln
                 165                 170                 175    
 Pro Leu Thr Thr Val Gln Asn Ala Asn Asp Cys Cys Cys Asp Gly Ala
             180                 185                 190        
 Cys Ser Ser Thr Pro Thr Leu Ser Glu Asn Val Ser Gly Thr Arg Tyr
         195                 200                 205            
 Ser Trp Lys Val Ser Gly Met Asp Cys Ala Ala Cys Ala Arg Lys Val
     210                 215                 220                
 Glu Asn Ala Val Arg Gln Leu Ala Gly Val Asn Gln Val Gln Val Leu
 225                 230                 235                 240
 Phe Ala Thr Glu Lys Leu Val Val Asp Ala Asp Asn Asp Ile Arg Ala
                 245                 250                 255    
 Gln Val Glu Ser Ala Leu Gln Lys Ala Gly Tyr Ser Leu Arg Asp Glu
             260                 265                 270        
 Gln Ala Ala Glu Glu Pro Gln Ala Ser Arg Leu Lys Glu Asn Leu Pro
         275                 280                 285            
 Leu Ile Thr Leu Ile Asp Ser Ser Tyr Phe Pro His Gly Thr Glu Leu
     290                 295                 300                
 Ala Phe
 305    



      <210> 2777
      <211> 76
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(76)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2777
 Phe Pro Cys Pro Pro Ala Pro His Val Cys Gly Pro Pro Pro Cys Pro
   1               5                  10                  15    
 Arg Ala Phe Pro Val Gly Gln Ser Ser Ser Gln Pro Gln Val Ala Thr
              20                  25                  30        
 Gly Phe Pro Xaa Ser Pro Val Cys Pro Pro Pro Arg Leu Tyr Trp Gly
          35                  40                  45            
 Pro Gly Thr Glu Arg His Trp Val Glu Thr His Tyr Arg Ala Phe Leu
      50                  55                  60                
 Pro Ser Gln His Leu Ser Ser Pro Val Thr Ala Ala
  65                  70                  75    



      <210> 2778
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 2778
 Val Leu Val Arg Asp Pro Ser Gln Pro Ala Gln Pro Phe Ser Val Ser
   1               5                  10                  15    
 Phe Ser Pro Gln Lys His Arg Asp Glu Lys Leu Tyr Phe Leu Pro Lys
              20                  25                  30        
 Gly Val Ser Gly Gly Ser Glu Leu Arg Gly Arg Pro Gln Pro Tyr Leu
          35                  40                  45            
 Pro Cys Pro Val Ser Pro Thr Leu Cys Pro Trp Gly His Leu Ser Leu
      50                  55                  60                
 Ala Pro Pro Ser Val Pro Pro Thr Ala Cys Glu Ser Ser Ser Glu Leu
  65                  70                  75                  80
 Trp Pro Ser Leu Ser Trp Thr Trp Ala Glu
                  85                  90



      <210> 2779
      <211> 61
      <212> PRT
      <213> Homo sapiens


      <400> 2779
 Met Pro Leu His Thr Cys Leu Val His Val Gly Val Ser His Ala Ala
   1               5                  10                  15    
 Arg Gly Ser Pro Val Cys Pro Ser Val Leu Trp Val Trp Phe Cys Val
              20                  25                  30        
 His Phe Gln Val Ile His Met Trp Ala His Glu Cys Val Gln Ala Asp
          35                  40                  45            
 Val Trp Ala His Ile Gln Asp Cys Ala Gln Val Cys Val
      50                  55                  60    



      <210> 2780
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 2780
 Ala Ala Ala Asn Arg Lys Arg Ala Ala Tyr Tyr Ser Ala Ala Gly Pro
   1               5                  10                  15    
 Arg Pro Gly Ala Asp Arg His Gly Arg Tyr Gln Leu Glu Asp Glu Ser
              20                  25                  30        
 Ala His Leu Asp Glu Met Pro Leu Met Met Ser Glu Glu Gly Phe Glu
          35                  40                  45            
 Asn Glu Glu Ser Asp Tyr His Thr Leu Pro Arg Ala Arg Ile Met Gln
      50                  55                  60                
 Arg Lys Arg Gly Leu Glu Trp Phe Val Cys Asp Gly Trp Lys Phe Leu
  65                  70                  75                  80
 Cys Thr Ser Cys Cys Gly Trp Leu Ile Asn Ile Cys Arg Arg Lys Lys
                  85                  90                  95    
 Glu Leu Lys Ala Arg Thr Val Trp Leu Gly Cys Pro Glu Lys Cys Glu
             100                 105                 110        
 Glu Lys His Pro Arg Asn Ser Ile Lys Asn Gln Lys Tyr Asn Val Phe
         115                 120                 125            
 Thr Phe Ile Pro Gly Val Leu Tyr Glu Gln Phe Lys Phe Phe Leu Asn
     130                 135                 140                
 Leu Tyr Phe Ala Val Ile Ser Cys Ser Gln Phe Val Thr Ala Leu Lys
 145                 150                 155                 160
 Ile Gly Tyr Leu Tyr Thr Tyr Trp Ala Pro Leu Gly Phe
                 165                 170            



      <210> 2781
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 2781
 Glu Gln Phe Leu Arg Arg Gln Ile Ala Ser Glu Lys Glu Glu Ile Glu
   1               5                  10                  15    
 Arg Leu Lys Ala Glu Ile Ala Glu Ile Gln Ser Arg Gln Gln His Gly
              20                  25                  30        
 Arg Ser Glu Thr Glu Glu Tyr Ser Ser Leu Leu Leu Gln Phe
          35                  40                  45    



      <210> 2782
      <211> 133
      <212> PRT
      <213> Homo sapiens


      <400> 2782
 Gly Asn Gly Gly Phe Val Val His Trp Leu Asn Asn Lys Glu Phe His
   1               5                  10                  15    
 Phe Thr Ser Ser Thr Glu Val Phe Met His Gln Leu Arg Lys Leu Ser
              20                  25                  30        
 Asp Lys Gln Val Asp His Glu Asn Asp Asp Ala Asp Arg Glu Asp Glu
          35                  40                  45            
 Glu His Ser Gln Glu Asp Arg Glu Arg Gly Leu His Met Lys Leu Asp
      50                  55                  60                
 His Asp Leu Ser Leu Asp Arg Glu Ser Glu Ala Gly Thr Gly Ser Ser
  65                  70                  75                  80
 Glu His Glu Asp Gly Glu Arg Glu Gly Ser Pro Arg Thr Tyr Ser Arg
                  85                  90                  95    
 Leu Ser Val Pro Met Pro Leu Pro Thr Val Leu Leu Asp Arg Lys Ile
             100                 105                 110        
 Glu Thr Leu Leu Thr Glu Trp Asn Lys Asn Pro Asp Met Leu Phe Thr
         115                 120                 125            
 Ile His Pro Met Tyr
     130            



      <210> 2783
      <211> 241
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(241)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2783
 Ile Ser Val Phe Arg Ser Pro Gly Gln Ser Thr Ser Gln His Asp Ala
   1               5                  10                  15    
 Ala Thr Trp Pro Phe Leu His Ile Ser Gly Glu Gly Pro Thr Pro Ser
              20                  25                  30        
 Arg Arg Lys Ala Pro Pro Ala Phe His Pro His Thr Gln Ala Cys Pro
          35                  40                  45            
 Ser Thr Cys Tyr Cys His Thr Leu Ala Ser Arg Arg Gly Pro Cys Asn
      50                  55                  60                
 Gly Arg Tyr His Arg Pro Val Tyr Pro His Pro Thr Ala Met Gln Arg
  65                  70                  75                  80
 Asp Pro Pro Ala Gly Pro Arg Gly Cys Gln Ser Pro Cys Trp His Tyr
                  85                  90                  95    
 Thr Pro Ala Cys Arg His Pro Cys Gly Arg His Tyr Arg Xaa His Gly
             100                 105                 110        
 Gln His Asp Pro Pro Pro Trp Gln Xaa His Cys Xaa Phe Gly Ser Pro
         115                 120                 125            
 Gly Gln Ser Thr Ser Gln His Asp Ala Val Thr Trp Pro Phe Leu His
     130                 135                 140                
 Ile Pro Gly Glu Arg Pro Thr Ala Ser Arg Arg Lys Ala Pro Pro Ala
 145                 150                 155                 160
 Phe His Pro His Thr Gln Ala Cys Pro Ser Ala Cys Tyr Cys His Thr
                 165                 170                 175    
 Leu Ala Ser Arg Arg Gly Pro Ser Asn Gly Arg Tyr His Arg Pro Gly
             180                 185                 190        
 Tyr Pro His Pro Thr Ala Val Gln Arg Asp Pro Pro Ala Gly Pro Arg
         195                 200                 205            
 Gly Cys Gln Ser Pro Cys Xaa His Glu Pro Pro Ala Cys Arg His Pro
     210                 215                 220                
 Cys Gly Arg His Tyr Arg Xaa His Gly Gln His Asp Pro Pro Pro Trp
 225                 230                 235                 240
 Gln
    



      <210> 2784
      <211> 68
      <212> PRT
      <213> Homo sapiens


      <400> 2784
 Met Ser Leu Val Lys Leu Phe Asn Leu Leu Val Phe Ser Tyr Arg Arg
   1               5                  10                  15    
 Gly Ala Val Ile Thr Ile Lys Ile Glu Val Lys Ile Lys Val Thr Tyr
              20                  25                  30        
 Val Lys Cys Gln Ala His Gly Glu Arg Leu Ile Asn Gly His Tyr Asp
          35                  40                  45            
 Tyr Ser Ala Cys His Val Ile Lys Leu Met Phe Cys Ala Glu Glu Lys
      50                  55                  60                
 Lys Pro His Gln
  65            



      <210> 2785
      <211> 153
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(153)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2785
 Thr Gly Glu Lys Val Val Pro Gly Glu Val Asn Pro Pro Asn Gly Pro
   1               5                  10                  15    
 Val Gly Asp Pro Leu Ser Leu Leu Phe Gly Asp Val Thr Ser Leu Lys
              20                  25                  30        
 Ser Phe Asp Ser Leu Thr Gly Cys Gly Asp Ile Ile Ala Glu Gln Asp
          35                  40                  45            
 Met Asp Ser Met Thr Asp Ser Met Ala Ser Gly Gly Gln Arg Ala Asn
      50                  55                  60                
 Arg Asp Gly Thr Lys Arg Ser Ser Cys Leu Val Thr Tyr Gln Gly Gly
  65                  70                  75                  80
 Gly Glu Glu Met Ala Leu Pro Asp Asp Asp Asp Glu Glu Glu Glu Glu
                  85                  90                  95    
 Glu Glu Glu Val Glu Leu Glu Glu Glu Glu Glu Glu Val Lys Glu Glu
             100                 105                 110        
 Glu Glu Asp Asp Asp Leu Glu Tyr Leu Xaa Glu Gly Ser Thr Arg Arg
         115                 120                 125            
 Gly Lys Pro Thr Gln Trp Pro Cys Gly Gly Pro Thr Glu Pro Leu Val
     130                 135                 140                
 Trp Gly Cys Asp Ile Pro Glu Lys Leu
 145                 150            



      <210> 2786
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 2786
 Gln Pro Gln Tyr Ile Ala Pro Leu Met Ala Asn Phe Asp Pro Ser Val
   1               5                  10                  15    
 Ser Arg Asn Ser Thr Val Arg Tyr Phe Asp Asn Gly Thr Ala Leu Val
              20                  25                  30        
 Val Gln Trp Asp His Val His Leu Gln Asp Asn Tyr Asn Leu Gly Ser
          35                  40                  45            
 Phe Thr Phe Gln Ala Thr Leu Leu Met Asp Gly Arg Ile Ile Phe Gly
      50                  55                  60                
 Tyr Lys Glu Ile Pro Val Leu Val Thr Gln Ile Ser Ser Thr Asn His
  65                  70                  75                  80
 Pro Val Lys Val Gly Leu Ser Asp Ala Phe Val Val Val His Arg Ile
                  85                  90                  95    
 Gln Gln Ile Pro Ser Thr
             100        



      <210> 2787
      <211> 23
      <212> PRT
      <213> Homo sapiens


      <400> 2787
 Phe His His Lys Gln Leu His Asn Pro Val Leu Glu Cys His Gln Pro
   1               5                  10                  15    
 Ala Gly Pro Cys His Tyr Leu
              20            



      <210> 2788
      <211> 403
      <212> PRT
      <213> Homo sapiens


      <400> 2788
 Trp Thr Pro Pro Gly Ala Pro Gly Ala Lys Gly Pro Arg Gln Gly Gly
   1               5                  10                  15    
 Cys Cys Ser Gly Leu Leu Arg Pro Pro Arg Val Ser Gly Lys Thr Cys
              20                  25                  30        
 Gly Ala Arg Pro Pro Trp Pro Trp Arg Ser Leu Ser Arg Ile Pro Lys
          35                  40                  45            
 Arg Glu Gly Leu Gly Glu Glu Asp Thr Ala Val Ala Gly His Glu Leu
      50                  55                  60                
 Leu Leu Pro Asn Glu Arg Ser Phe Gln Asn Ala Ala Lys Ser Asn Asn
  65                  70                  75                  80
 Leu Asp Leu Met Glu Lys Leu Phe Glu Lys Lys Val Asn Ile Asn Val
                  85                  90                  95    
 Val Asn Asn Met Asn Arg Thr Ala Leu His Phe Ala Val Gly Arg Asn
             100                 105                 110        
 His Leu Ser Ala Val Asp Phe Leu Leu Lys His Lys Ala Arg Val Asp
         115                 120                 125            
 Val Ala Asp Lys Thr Arg Met Arg Glu Leu Leu Leu Glu Ile Phe Leu
     130                 135                 140                
 Thr Val Pro Arg Ala Gln Phe His Asp Leu His Cys Leu Glu Ser Lys
 145                 150                 155                 160
 Leu Glu Asp Cys Glu Met Arg Asp Thr Leu Arg His Met Gln Ala Val
                 165                 170                 175    
 Tyr Arg Glu Thr Asn Ile Leu Thr His Thr Val Thr Cys Val Arg Leu
             180                 185                 190        
 Gly Ala Leu Ser Tyr Leu Lys Thr Met Ala Cys Arg Pro Gln Gln Asn
         195                 200                 205            
 Ile Leu Ser Asp Lys Asn Met Asp Ser Val Leu Thr Ser Tyr Met Asn
     210                 215                 220                
 Leu Gly Lys Leu His Asn Leu Ser Val Leu Gln Phe Leu Tyr Leu Lys
 225                 230                 235                 240
 Asn Glu Asp Lys Asn Ser Thr Tyr Val Asn Leu Ile Leu Ser Glu Arg
                 245                 250                 255    
 Ile Pro Thr Leu Ile Phe Gln Ile Gln Lys Pro Lys Tyr Arg Glu Val
             260                 265                 270        
 Met Gln Leu Ala Gln Met Leu Val Val Leu Ala Leu Thr Leu Phe Ser
         275                 280                 285            
 Phe Thr Val Val Val Leu Asn Ser Ile Arg Ala Met Val Pro Ser Glu
     290                 295                 300                
 Arg Ile Phe Lys Ala Lys Asp Leu Leu Ser Arg Lys Ile His Ile His
 305                 310                 315                 320
 Ile Tyr Asp Lys Asn Ile Ala Tyr Glu Ser Ala Val Pro Ile Met Pro
                 325                 330                 335    
 Val Ile Pro Gln Thr Gly Ser Pro Thr Tyr Thr Ser Ser Ala Ala Leu
             340                 345                 350        
 Pro Gln Cys Leu Thr Pro Gly Asn Thr Ile His Ser Val Ala Ile Val
         355                 360                 365            
 Asn Gly Ser Ser Trp Ser Ser Ala Leu Arg Ser Gln Cys Asp His Arg
     370                 375                 380                
 Leu His Thr Cys Ser Phe Thr Leu Val Pro Gln Arg His Pro His Thr
 385                 390                 395                 400
 Gln Leu Ile
            



      <210> 2789
      <211> 111
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(111)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2789
 Phe Arg Ala Asn Arg Thr Val Lys Asp Ala His Ser Ile His Gly Thr
   1               5                  10                  15    
 Asn Pro Gln Tyr Leu Val Glu Lys Ile Ile Arg Thr Arg Ile Tyr Glu
              20                  25                  30        
 Ser Lys Tyr Trp Lys Glu Glu Cys Phe Gly Leu Thr Ala Glu Leu Val
          35                  40                  45            
 Val Asp Lys Ala Met Glu Leu Arg Phe Val Gly Gly Val Tyr Gly Gly
      50                  55                  60                
 Asn Ile Lys Pro Thr Pro Phe Leu Cys Leu Thr Leu Lys Met Leu Gln
  65                  70                  75                  80
 Ile Gln Pro Glu Lys Asp Ile Ile Val Glu Phe Ile Lys Asn Glu Asp
                  85                  90                  95    
 Phe Lys Xaa Val Gln Cys Ser Leu Ala Asn Ile Arg Gly Met Tyr
             100                 105                 110    



      <210> 2790
      <211> 598
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(598)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2790
 Ala Met Leu Pro Met Glu Leu Gly Cys Gly Pro Leu Pro Glu Pro Leu
   1               5                  10                  15    
 Pro Val Gly Cys Ser Arg Phe Ser Leu Phe Lys Xaa Gln Thr Cys Ile
              20                  25                  30        
 Ser Thr Val Pro Gly Tyr Met Val Thr Ala Gln Ser Met Ser Ser Thr
          35                  40                  45            
 Pro Pro Pro Pro Ser Pro Ser Thr Leu Pro Ser Ser Pro Ser Pro Pro
      50                  55                  60                
 Pro Pro Leu Pro Gln Pro Leu Pro Pro Pro Pro Pro Ser Pro Pro Thr
  65                  70                  75                  80
 Leu Ser Ser Leu Ser Ser Pro Ser Pro Pro Arg Pro Pro Leu Val Ser
                  85                  90                  95    
 Pro Ser Thr Leu Pro Ser Pro Gln Pro Ser Ser Pro Gln Pro Leu Leu
             100                 105                 110        
 Pro Pro Ser Ser Ser Pro Pro Ser Leu Pro Ser Pro Pro Pro Pro Ser
         115                 120                 125            
 Pro Pro Leu Pro Ser Pro Ser Pro Ser Ala Ile Pro Ser Leu Pro Pro
     130                 135                 140                
 Pro Ser Pro Gln Pro Leu Pro Pro Pro Pro Pro Ser Ser Pro Pro Pro
 145                 150                 155                 160
 Ser Leu Pro Ser Pro Leu Leu Pro Pro Pro Pro Leu Ser Ser Ser Pro
                 165                 170                 175    
 Ser Ser Pro Leu Ser Pro Ser Pro Pro Pro Pro Ser Pro Pro Pro Ser
             180                 185                 190        
 Leu Pro Pro Ser Pro Pro Pro Ser Pro Pro Pro Pro Pro Pro Pro Gln
         195                 200                 205            
 Pro Pro Ser Pro Pro Ser Ser Pro Leu Ser Ser Pro Pro Leu Ser Ser
     210                 215                 220                
 Ser Gln Pro Ser Leu Leu Pro Pro Ser Leu Ser Ser Leu Pro Leu Pro
 225                 230                 235                 240
 Ser Ser Pro Ser Pro Leu Leu Pro Leu Ser Leu Pro Leu Ser Ile Ser
                 245                 250                 255    
 Pro Pro Xaa Leu Ser Leu Leu Ser Pro Leu Pro Pro Ser Pro Ser Leu
             260                 265                 270        
 Pro Pro Ser Ser Phe Gln Ser Thr Xaa Thr Ile Gly Gln Cys Phe Ser
         275                 280                 285            
 Leu Val Met Trp His Val Ala Pro Cys Thr Tyr Leu Ala Leu Ala Gly
     290                 295                 300                
 Asn Thr Leu Met Ala Trp Pro Leu Met Ser Ala Ser Ser Lys Ala Ser
 305                 310                 315                 320
 Gly Gly Val Ser Met Phe Val Trp Arg Asn Val Glu Pro Cys Ser Val
                 325                 330                 335    
 Ala Val Phe Ser Trp Tyr Ser Val Pro Phe Leu Thr Pro Pro Cys Ser
             340                 345                 350        
 Arg Val Arg Pro Ser Asn Leu Pro Val Thr Gln Trp Pro Pro Thr Arg
         355                 360                 365            
 Ala Lys Asn Leu Pro Ser Arg Gln Leu Leu Leu Thr Ser Val His Gln
     370                 375                 380                
 Ala Gln Ser Leu Ser Ala Leu Cys Lys Glu Gln Asp Ser Ser Ser Glu
 385                 390                 395                 400
 Lys Asp Gly Arg Ser Pro Asn Lys Trp Asp Lys Asp His Ile Trp Trp
                 405                 410                 415    
 Pro Met Ser Gly Gly His Asp Leu Gln Gln Ala Ala Pro Gly Pro Gly
             420                 425                 430        
 Arg Ala His Gln Gly His Pro Tyr Gln Asp Asn Trp Thr Ile Ser Gln
         435                 440                 445            
 Ile Leu Ser Glu Arg Trp Tyr Thr Leu Gly Pro Asn Glu Met Gln Lys
     450                 455                 460                
 Tyr His Asp Leu Ala Phe Gln His Met Ala Gly Glu Asp Ile Ala Ser
 465                 470                 475                 480
 Asp Glu Glu His Met Val Ile His Glu Glu Glu Gly Val Met Val Ser
                 485                 490                 495    
 Leu Leu Met Thr Ala Leu Ala Pro Leu Thr Leu Ile Ser Ser Ser Arg
             500                 505                 510        
 Ile Phe Gly Lys Val Tyr Gly Pro Thr Pro Ser Ser Ser Tyr Thr Tyr
         515                 520                 525            
 Ser Asp Ala Ser Ser Ser Thr Leu Ala Pro Thr Ser Phe Leu Leu Gly
     530                 535                 540                
 Pro Gly Ala Phe Lys Ala Gln Glu Ser Gly Glu Glu Ala Glu Asp Gly
 545                 550                 555                 560
 Leu Arg Glu Leu Glu Thr Glu Lys Ala Leu Ser Ser Ser Leu Arg Arg
                 565                 570                 575    
 Ala Leu Asp Gln Xaa Leu Ala Leu Ile Met Gln Leu Phe Gln Ala His
             580                 585                 590        
 Cys Phe Phe Leu Ser Thr
         595            



      <210> 2791
      <211> 783
      <212> PRT
      <213> Homo sapiens


      <400> 2791
 Ala Ile Cys Asp Pro Cys Tyr Trp Arg Met Glu Lys Ser Pro Arg Met
   1               5                  10                  15    
 Met Glu Lys Lys Leu Ser Lys Gly Met Ile Pro Asp Trp Glu Ser Arg
              20                  25                  30        
 Trp Glu Asn Lys Glu Leu Ser Thr Lys Lys Asp Asn Tyr Asp Glu Asp
          35                  40                  45            
 Ser Pro Gln Thr Val Ile Ile Glu Lys Val Val Lys Gln Ser Tyr Glu
      50                  55                  60                
 Phe Ser Asn Ser Lys Lys Asn Leu Glu Tyr Ile Glu Lys Leu Glu Gly
  65                  70                  75                  80
 Lys His Gly Ser Gln Val Asp His Phe Arg Pro Ala Ile Leu Thr Ser
                  85                  90                  95    
 Arg Glu Ser Pro Thr Ala Asp Ser Val Tyr Lys Tyr Asn Ile Phe Arg
             100                 105                 110        
 Ser Thr Phe His Ser Lys Ser Thr Leu Ser Glu Pro Gln Lys Ile Ser
         115                 120                 125            
 Ala Glu Gly Asn Ser His Lys Tyr Asp Ile Leu Lys Lys Asn Leu Pro
     130                 135                 140                
 Lys Lys Ser Val Ile Lys Asn Glu Lys Val Asn Gly Gly Lys Lys Leu
 145                 150                 155                 160
 Leu Asn Ser Asn Lys Ser Gly Ala Ala Phe Ser Gln Gly Lys Ser Leu
                 165                 170                 175    
 Thr Leu Pro Gln Thr Cys Asn Arg Glu Lys Ile Tyr Thr Cys Ser Glu
             180                 185                 190        
 Cys Gly Lys Ala Phe Gly Lys Gln Ser Ile Leu Asn Arg His Trp Arg
         195                 200                 205            
 Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Arg Glu Cys Gly Lys Thr
     210                 215                 220                
 Phe Ser His Gly Ser Ser Leu Thr Arg His Leu Ile Ser His Ser Gly
 225                 230                 235                 240
 Glu Lys Pro Tyr Lys Cys Ile Glu Cys Gly Lys Ala Phe Ser His Val
                 245                 250                 255    
 Ser Ser Leu Thr Asn His Gln Ser Thr His Thr Gly Glu Lys Pro Tyr
             260                 265                 270        
 Glu Cys Met Asn Cys Gly Lys Ser Phe Ser Arg Val Ser His Leu Ile
         275                 280                 285            
 Glu His Leu Arg Ile His Thr Gln Glu Lys Leu Tyr Glu Cys Arg Ile
     290                 295                 300                
 Cys Gly Lys Ala Phe Ile His Arg Ser Ser Leu Ile His His Gln Lys
 305                 310                 315                 320
 Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Arg Glu Cys Gly Lys Ala
                 325                 330                 335    
 Phe Cys Cys Ser Ser His Leu Thr Arg His Gln Arg Ile His Thr Met
             340                 345                 350        
 Glu Lys Gln Tyr Glu Cys Asn Lys Cys Leu Lys Val Phe Ser Ser Leu
         355                 360                 365            
 Ser Phe Leu Val Gln His Gln Ser Ile His Thr Glu Glu Lys Pro Phe
     370                 375                 380                
 Glu Cys Gln Lys Cys Arg Lys Ser Phe Asn Gln Leu Glu Ser Leu Asn
 385                 390                 395                 400
 Met His Leu Arg Asn His Ile Arg Leu Lys Cys Asp Phe Tyr Leu Met
                 405                 410                 415    
 Asn Ala Ile Tyr Val Gly Lys Pro Leu Val Ile Gly His Pro Cys Phe
             420                 425                 430        
 Asn Ile Thr Glu Phe Ile Leu Glu Arg Asn Leu Thr Asn Val Leu Asn
         435                 440                 445            
 Val Gly Arg Pro Ser Ala Val Val Gln Thr Leu Pro Tyr Ile Arg Glu
     450                 455                 460                
 Phe Ile Leu Glu Lys Ser His Ile Asn Val Val Ser Val Gly Lys Leu
 465                 470                 475                 480
 Leu Ala Lys Ala Gln Ile Leu Leu Pro Ile Lys Glu Tyr Ile Met Glu
                 485                 490                 495    
 Arg Asn Pro Ile Val Trp Glu Pro Leu Gln Pro Val Val Ser Arg Gln
             500                 505                 510        
 Ala Leu Gly His Gln Ala Gly Glu Ser Arg Gly His Thr Gln Arg Cys
         515                 520                 525            
 Lys Val Thr Arg Leu Ser Ser Trp Gln Val Leu Val Gly Ala Ala Val
     530                 535                 540                
 Pro Cys Ser Gly Ala Arg Asp Arg Val Pro Val Pro Arg His Val Pro
 545                 550                 555                 560
 Gln Ala Cys Leu Gln Gly Arg Val Gln Thr Gly Arg Leu Asp Trp Arg
                 565                 570                 575    
 Gly His Ala Cys Ser Ala Ser Pro Asn Ala Val Pro Thr Val Thr Phe
             580                 585                 590        
 Ser Asp Val Ala Ile Asp Phe Ser His Glu Glu Trp Ala Cys Leu Asp
         595                 600                 605            
 Ser Ala Gln Arg Asp Leu Tyr Lys Asp Val Met Val Gln Asn Tyr Glu
     610                 615                 620                
 Asn Leu Val Ser Val Gly Leu Ser Ile Thr Lys Pro Tyr Val Ile Thr
 625                 630                 635                 640
 Leu Leu Glu His Gly Lys Glu Pro Trp Met Val Glu Lys Lys Leu Ser
                 645                 650                 655    
 Lys Gly Met Ile Pro Val Leu Glu Val Leu Ala Arg Ala Met Arg Gln
             660                 665                 670        
 Lys Asn Glu Ile Lys Gly Ile Gln Leu Gly Lys Glu Glu Val Lys Leu
         675                 680                 685            
 Ser Leu Phe Ala Asp Asp Met Ile Val Tyr Leu Glu Asn Pro Ile Val
     690                 695                 700                
 Ser Ala Gln Asn Leu Leu Lys Leu Ile Ser Asn Phe Ser Lys Val Ser
 705                 710                 715                 720
 Glu Ile Pro Lys Ser Met Tyr Lys Asn His Lys Ala Phe Leu Tyr Thr
                 725                 730                 735    
 Asn Asn Arg Gln Thr Glu Ser Gln Ile Met Ser Glu Leu Pro Phe Thr
             740                 745                 750        
 Ile Ala Ser Lys Arg Ile Lys Tyr Leu Gly Ile Gln Leu Thr Arg Asp
         755                 760                 765            
 Val Lys Asp Leu Phe Lys Glu Asn Tyr Lys Pro Cys Ser Thr Lys
     770                 775                 780            



      <210> 2792
      <211> 102
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(102)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2792
 Ile Pro Ala Ala Ala Thr Cys Met Gly Ser Leu Leu Gly Gly Xaa Glu
   1               5                  10                  15    
 Thr Pro Gly Leu Trp Ala Arg Arg Ser Val Lys Ser Arg Gly Leu Phe
              20                  25                  30        
 Pro Gly Leu Pro Ser Pro Ser Arg Ala Ser Val Arg Ser Leu Leu Leu
          35                  40                  45            
 Leu Pro Ala Trp Ala Ala Phe Leu Glu Gly Ile Val Asp Thr Arg Pro
      50                  55                  60                
 Thr Ala Trp Arg Ala Phe Pro Trp Thr Leu Phe Leu Ser Val Phe Cys
  65                  70                  75                  80
 Gln Phe Leu Asp Phe Pro Glu Thr Ser Leu Asp Ser Gln Lys Leu Ser
                  85                  90                  95    
 Leu Asp Thr Pro Ser Phe
             100        



      <210> 2793
      <211> 77
      <212> PRT
      <213> Homo sapiens


      <400> 2793
 Ile Leu Leu Gln Arg Ser Leu Gly Val Gly Gly His Arg Ala Trp Gly
   1               5                  10                  15    
 Ile Gln Glu Pro Ser Lys Val Leu Val Ser Gly Arg Arg Thr Glu Ala
              20                  25                  30        
 Pro Ser Met Leu Gln Met Gly Arg Gln Met Trp Gly Arg Thr Ser Trp
          35                  40                  45            
 Arg Trp Thr Arg Thr Trp Arg Cys Gly Trp Pro Trp Gly Gly Pro Leu
      50                  55                  60                
 Ala Ala Arg His Val Ser Ser Cys Thr Lys Gln Gly His
  65                  70                  75        



      <210> 2794
      <211> 79
      <212> PRT
      <213> Homo sapiens


      <400> 2794
 Ile Phe Thr Leu Phe Asp Lys Leu Ser Ser Gln Ile Pro Ser Ile Leu
   1               5                  10                  15    
 Arg Ser Gln Tyr Gln Ser Cys Leu Tyr Asp Pro Ser Gln Pro Trp Pro
              20                  25                  30        
 Pro Pro Thr Ser Asp Ala His Asp His Lys His Gly Pro His Ile Ala
          35                  40                  45            
 Pro Pro Pro Pro Leu Pro Cys Leu Leu Gly Leu Ala Ser Pro Phe Arg
      50                  55                  60                
 Ser Ile Gln Tyr Ile Ser Ala Arg Pro Gln Leu Lys Gly Pro Phe
  65                  70                  75                



      <210> 2795
      <211> 235
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(235)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2795
 Val Thr Ala Gly Val Pro Lys Gly His Cys Pro Arg Arg Gly Thr Ser
   1               5                  10                  15    
 Ser Ala Ile Ala Ser Cys Pro Pro Tyr Gly Ser Pro Pro Arg Ala Glu
              20                  25                  30        
 Cys Ala Leu Arg Ala Gly Ser Thr Val Thr Thr Xaa Arg Arg Ser Cys
          35                  40                  45            
 Cys Thr Ser Tyr Ser Ser Gly Arg Pro Pro Thr Gly Arg Arg Gly Ser
      50                  55                  60                
 Trp Thr Leu Val Cys Thr Ser Cys Cys Ala Ser Trp Arg Arg Ala Cys
  65                  70                  75                  80
 Ser Arg Arg Ser Ser Thr Ser Ser Ser Ser Ala Thr Ala Arg Cys Leu
                  85                  90                  95    
 Arg Pro Trp Asp Ser Leu Arg Pro Cys Ser Gly Pro Ser Pro Ser Thr
             100                 105                 110        
 Ser Ser Gly Pro Ser Ser Cys Ser Glu Ala Phe Thr Val Arg His Trp
         115                 120                 125            
 Thr Pro Ser Met Arg Cys Ser Arg Met Pro Gln Arg Ser Leu Ala Ser
     130                 135                 140                
 Ile Pro Tyr Met Ser Ser Ser Asp Gln Pro Thr Pro Lys Ser Xaa Arg
 145                 150                 155                 160
 Leu Leu Gln Asn Val Gly Ser Ser Ser Xaa Asp Glu Gly Ile Pro His
                 165                 170                 175    
 Val His Thr Pro Gly Gly Ile Cys Gln Pro Cys Ser Gly Asp Lys Ala
             180                 185                 190        
 Gly Phe Arg Gly Ser Arg Ala Gln Pro Ala Arg Lys Pro Ser Pro Thr
         195                 200                 205            
 Val Gln Arg Lys Gln Asn Phe Asn Gly Lys Leu Val Cys Phe Ile Pro
     210                 215                 220                
 Leu Gly Ser Ala Gly Lys Ala Val Ile Trp Val
 225                 230                 235



      <210> 2796
      <211> 196
      <212> PRT
      <213> Homo sapiens


      <400> 2796
 Phe Gln Gly Arg Gly Leu Ala Ala Asn Asp Gly Glu Tyr Leu Lys Leu
   1               5                  10                  15    
 Gln Trp Arg Ala Gly Thr Leu Val Leu Ala Pro Ser Cys Pro Leu Ser
              20                  25                  30        
 Thr Leu Ser Val Leu Ser Ser Pro Pro Arg Glu Leu Gln Ala Met Glu
          35                  40                  45            
 Ala Leu Gln Asn Gly Gln Thr Thr Val Glu Gly Ser Ile Glu Gly Gln
      50                  55                  60                
 Ser Ala Gly Ala Ala Ser His Ala Met Ile Glu Lys Ile Leu Ser Glu
  65                  70                  75                  80
 Glu Pro Arg Trp Gln Glu Thr Ala Tyr Val Leu Gly Asn Tyr Lys Thr
                  85                  90                  95    
 Glu Pro Cys Lys Lys Pro Pro Arg Leu Cys Arg Gln Gly Tyr Ala Cys
             100                 105                 110        
 Pro Tyr Tyr His Asn Ser Lys Asp Arg Arg Arg Ser Pro Arg Lys His
         115                 120                 125            
 Lys Tyr Arg Ser Leu Gly Thr Gln Glu Ala Ser His Gly Arg Glu Glu
     130                 135                 140                
 Trp Gln Gly Arg Gly Gln Ala Glu Ala Ala Pro Thr Gly Ser Pro Gly
 145                 150                 155                 160
 Gly Gly Glu Ala Gly Pro Gly Asp Asp Arg Ile Ala Ser Pro Gly Pro
                 165                 170                 175    
 Arg Gly Gly His Ser Glu Asp Ser Trp Thr Val Gly Ala Gln Leu His
             180                 185                 190        
 Leu Leu His Glu
         195    



      <210> 2797
      <211> 166
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(166)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2797
 Ile Glu Leu Arg Ala Val Ala Gln Gly Ile Ala Gln Ser Leu Gly Gln
   1               5                  10                  15    
 Leu Leu Phe Thr Gln Cys Pro Leu Glu Lys Lys Asp Leu Glu Gly Leu
              20                  25                  30        
 Phe Leu Gln Asn Asn Lys Glu Gly Val Gln Lys Gly Arg Asp Glu Pro
          35                  40                  45            
 Leu Pro Pro Leu Pro Xaa Ala Thr Ala Leu Ser Ser Ile Gln Ala Gly
      50                  55                  60                
 Ile Gln Gln Ala Arg Xaa Glu Gly Asp Leu Glu Ala Trp Gln Phe Pro
  65                  70                  75                  80
 Val Arg Ile His Pro Pro Asp Gln Gln Gly Asn Ile Ile Val Thr Phe
                  85                  90                  95    
 Glu Pro Phe Pro Phe Lys Leu Phe Lys Glu Phe Lys Gln Ala Val Asn
             100                 105                 110        
 Gln Tyr Gly Pro Gly Ser Pro Phe Val Met Gly Leu Leu Lys Asn Val
         115                 120                 125            
 Ala Val Ser Ser Trp Met Ile Pro Thr Asp Trp Asp Ala Leu Thr Arg
     130                 135                 140                
 Ala Cys Leu Thr Pro Ala Gln Phe Leu Gln Phe Lys Thr Trp Trp Ala
 145                 150                 155                 160
 Asp Glu Ala Gly Arg Val
                 165    



      <210> 2798
      <211> 305
      <212> PRT
      <213> Homo sapiens


      <400> 2798
 Met Ser Thr Ala Val Val Val Lys Val Val Leu Cys Thr Val Ala Pro
   1               5                  10                  15    
 Gly Arg Gly Ser Ala Pro Ser Leu Ser Ser Cys Leu Asp Trp Lys Val
              20                  25                  30        
 Asn Gly Ala Glu Gly Ser His Asn Lys Asp Leu Phe Val Leu Thr Tyr
          35                  40                  45            
 Gly Ala Leu Val Ala Gln Leu Cys Lys Asp Tyr Glu Lys Asp Glu Asp
      50                  55                  60                
 Val Asn Gln Tyr Leu Asp Lys Met Gly Tyr Gly Ile Gly Thr Arg Leu
  65                  70                  75                  80
 Val Glu Asp Phe Leu Ala Arg Ser Cys Val Gly Arg Cys His Ser Tyr
                  85                  90                  95    
 Ser Glu Ile Ile Asp Ile Ile Ala Gln Asp Met Glu Arg Gly Phe Cys
             100                 105                 110        
 Ala Leu His Ile Asp Thr Glu Gly Arg Tyr Glu Trp Trp Thr Thr Ser
         115                 120                 125            
 Thr Gln Leu Gln Ser Thr Leu Pro Arg Ala Ala Gln Cys Ser Val Tyr
     130                 135                 140                
 Gln Lys Gln Pro Asp Arg Lys Ser Leu Thr Val Gly Gln Lys Ile Glu
 145                 150                 155                 160
 Val Gly Asn Pro Gly Ile Gly Thr Glu Gln Ser Pro Gln Gly Leu Val
                 165                 170                 175    
 Arg Phe Ala Thr Gln Ala Phe Leu Thr Thr His Arg Ala Glu Gly Leu
             180                 185                 190        
 Gln Gln Ser Gln Val Lys Gly Ser Val Ile His Leu Lys Ser Gln Asp
         195                 200                 205            
 Lys Cys Gly Glu His Arg Phe Thr Thr Asn Gln Val Glu Thr Gly Asp
     210                 215                 220                
 Pro Val Arg Glu Ser Ser Ser Gln His Ser Val Gly Arg Gly Gly Pro
 225                 230                 235                 240
 Lys Asp Ile Gln Ile Gln Gly Ala Asn Val Pro Val Arg Gln Cys Asn
                 245                 250                 255    
 Leu Leu Trp Arg Ile Thr Leu Gly Pro Leu Glu Thr Pro His Leu Glu
             260                 265                 270        
 Phe Ser Gly Glu Cys Ser Leu Leu Ala Ala Met Glu Ala Pro Glu His
         275                 280                 285            
 Thr Trp Asp Gln Glu Lys Ser Asp Ile Pro Glu Pro Pro His Arg Ser
     290                 295                 300                
 Ser
 305



      <210> 2799
      <211> 188
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(188)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2799
 Glu Lys Leu Leu Asn Pro Gln Thr Thr Ser Phe Phe Leu Gln Leu Leu
   1               5                  10                  15    
 Gln Lys Lys Gln Trp Tyr Pro Lys Ser Phe Pro Cys Cys Leu Pro Ser
              20                  25                  30        
 Gln Gly Leu Leu Pro Ala Ala Arg Val Gln Lys Cys Leu Leu Val Leu
          35                  40                  45            
 Arg Asn Val Ser Gly Ser Pro Phe Pro Phe Leu Ile Gly Phe Pro Pro
      50                  55                  60                
 Pro Ile Leu Glu Leu Lys Glu Ser Tyr Pro Trp Ala Gly Thr Asp Ile
  65                  70                  75                  80
 Gln Cys Glu Pro Ala Gln Gly His Val Leu Thr Ser Pro Ser Pro Thr
                  85                  90                  95    
 Leu Arg Leu Gln Gly Ala Pro Asp Leu Pro Ala Gly Glu Pro Ala Trp
             100                 105                 110        
 Leu Leu Leu Thr Ala Arg Glu Glu Asp Asp Gly Xaa Asn Phe Ser Cys
         115                 120                 125            
 Xaa Ala Ser Leu Val Val Gln Gly Gln Arg Leu Met Lys Thr Thr Val
     130                 135                 140                
 Ile Gln Leu His Ile Leu Cys Glu Trp Arg Pro Asp Leu Ser Cys Gln
 145                 150                 155                 160
 Asn Lys Asp Tyr Tyr Phe Pro Ile Ser Arg Glu Leu Leu Gly Gln Gln
                 165                 170                 175    
 Cys Phe Ile Ile Thr Val Ala Thr Phe Phe Ser Leu
             180                 185            



      <210> 2800
      <211> 382
      <212> PRT
      <213> Homo sapiens


      <400> 2800
 Met Val Gly Glu Cys Gly Thr Lys Leu Glu Val Met Gln Val His Leu
   1               5                  10                  15    
 Ser Asn Pro Arg Asp Glu Leu Glu Gly Glu Leu Arg Ser Ile Arg Val
              20                  25                  30        
 Thr Met Gly Gln Val Trp Ala Leu Val His Ser Thr Leu Glu Pro Phe
          35                  40                  45            
 His Thr Asn Glu Glu Glu Glu Gly Leu Tyr Asn Lys Val Thr Glu Glu
      50                  55                  60                
 Val Thr Glu Gln Val Cys Leu Pro Ala Lys Ala Lys Ala Ala Lys Glu
  65                  70                  75                  80
 Gly Glu Val His Pro Tyr Pro Ser Pro Phe Pro His Tyr Phe Glu Glu
                  85                  90                  95    
 Thr Glu Trp Pro Asp Pro Pro Asp Leu Ser Phe Leu Glu Asp Thr Gly
             100                 105                 110        
 Gly Asp Pro Ser Leu Thr Ser His Trp Gln Leu Thr Lys Glu Ala Glu
         115                 120                 125            
 Ala Glu Leu Gln Leu Ile Glu Lys Gln Val His Lys Ala Gln Ile Asn
     130                 135                 140                
 Arg Ile Asp Pro Glu Lys Ile Pro Asp Leu Leu Ile Phe Ser Thr Gln
 145                 150                 155                 160
 His Ser Pro Thr Gly Val Ile Val Gln Glu Gln Asp Leu Val Glu Trp
                 165                 170                 175    
 Leu Phe Leu Pro His Thr Asn Ser Trp Thr Leu Thr Pro Tyr Leu Asp
             180                 185                 190        
 Gln Asn Ala Thr Met Ile Gly Asn Glu Arg Thr Gln Ile Val Lys Leu
         195                 200                 205            
 His Gly Tyr Asp Pro Arg Lys Ile Ile Val Leu Leu Met Lys Ala Asn
     210                 215                 220                
 Ile Gln Gln Ala Phe Ile Asn Gly Leu Thr Trp Gln Thr His Leu Ala
 225                 230                 235                 240
 Asn Phe Val Val Ile Leu Asp Asn His Phe Pro Lys Met Lys Leu Phe
                 245                 250                 255    
 Gln Phe Leu Lys Leu Thr Asn Trp Ile Leu Pro Lys Ile Thr Lys Phe
             260                 265                 270        
 Lys Pro Ile Lys Gly Ala Glu Asn Val Phe Thr Asp Gly Ser Ser Asn
         275                 280                 285            
 Gly Lys Ala Ser Tyr Ser Gly Ser Lys Gly Leu Ser Gln Gln Leu Ile
     290                 295                 300                
 Trp Ile Ser Ser Arg Asn Leu Lys Pro Tyr His Glu Ser Asp Ala Glu
 305                 310                 315                 320
 Glu Glu Ile Pro Gly Arg Thr Gln Gly Thr Pro Gly Cys Ser His Val
                 325                 330                 335    
 Glu Thr Asp Thr Glu Glu Asp Pro Asn Cys His Glu Gln His Pro Leu
             340                 345                 350        
 Asn Thr Ala Thr His Leu Gly Thr Asp Gln Glu Ala Val Thr Asp Gly
         355                 360                 365            
 Gly Arg Lys Pro Glu Glu Arg Gly Thr Thr Ser His Asn Glu
     370                 375                 380        



      <210> 2801
      <211> 308
      <212> PRT
      <213> Homo sapiens


      <400> 2801
 Arg Pro Glu Pro Ser Cys Arg Pro Arg Ser Glu Tyr Gln Pro Ser Asp
   1               5                  10                  15    
 Ala Pro Phe Glu Arg Glu Thr Gln Tyr Gln Lys Asp Phe Arg Ala Trp
              20                  25                  30        
 Pro Leu Pro Arg Arg Gly Asp His Pro Trp Ile Pro Lys Pro Val Gln
          35                  40                  45            
 Ile Ser Ala Ala Ser Gln Ala Ser Ala Pro Ile Leu Gly Ala Pro Lys
      50                  55                  60                
 Arg Arg Pro Gln Ser Gln Glu Arg Trp Pro Val Gln Ala Ala Ala Glu
  65                  70                  75                  80
 Ala Arg Glu Gln Glu Ala Ala Pro Gly Gly Ala Gly Gly Leu Ala Ala
                  85                  90                  95    
 Gly Lys Ala Ser Gly Ala Asp Glu Arg Asp Thr Arg Arg Lys Ala Gly
             100                 105                 110        
 Pro Ala Trp Met Val Arg Arg Ala Glu Gly Leu Gly His Glu Gln Thr
         115                 120                 125            
 Pro Leu Pro Ala Ala Gln Ala Gln Val Gln Ala Thr Gly Pro Glu Ala
     130                 135                 140                
 Gly Arg Gly Arg Ala Ala Ala Asp Ala Leu Asn Arg Gln Ile Arg Glu
 145                 150                 155                 160
 Glu Val Ala Ser Ala Val Ser Ser Ser Tyr Arg Asn Glu Phe Arg Ala
                 165                 170                 175    
 Trp Thr Asp Ile Lys Pro Val Lys Pro Ile Lys Ala Lys Pro Gln Tyr
             180                 185                 190        
 Lys Pro Pro Asp Asp Lys Met Val His Glu Thr Ser Tyr Ser Ala Gln
         195                 200                 205            
 Phe Lys Gly Glu Ala Ser Lys Pro Thr Thr Ala Asp Asn Lys Val Ile
     210                 215                 220                
 Asp Arg Arg Arg Ile Arg Ser Leu Tyr Ser Glu Pro Phe Lys Glu Pro
 225                 230                 235                 240
 Pro Lys Val Glu Lys Pro Ser Val Gln Ser Ser Lys Pro Lys Lys Thr
                 245                 250                 255    
 Ser Ala Ser His Lys Pro Thr Arg Lys Ala Lys Asp Lys Gln Ala Val
             260                 265                 270        
 Ser Gly Gln Ala Ala Lys Lys Lys Ser Ala Glu Gly Pro Ser Thr Thr
         275                 280                 285            
 Lys Pro Asp Asp Lys Glu Gln Ser Lys Glu Met Asn Asn Lys Leu Ala
     290                 295                 300                
 Glu Ala Lys Glu
 305            



      <210> 2802
      <211> 138
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(138)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2802
 Thr Lys Tyr Trp Leu Leu Leu Phe Phe Leu Ile Leu Ile Leu Pro Phe
   1               5                  10                  15    
 Phe Phe Trp Arg Arg Ser Arg Ser Val Thr Gln Ala Gly Gly Gln Trp
              20                  25                  30        
 His Asp Leu Gly Ser Leu Gln Pro Pro Pro Pro Gly Phe Lys Gln Phe
          35                  40                  45            
 Ser Cys Leu Ser Leu Pro Ser Ser Trp Asp Tyr Arg Arg Ala Pro Leu
      50                  55                  60                
 His Leu Ala Asn Phe Tyr Ile Phe Ser Arg Asp Met Asp Phe Thr Met
  65                  70                  75                  80
 Leu Ala Arg Leu Val Ser Asn Ser Arg Ser Gln Cys Asp Pro Leu Ala
                  85                  90                  95    
 Ser Ala Ser Gln Ser Ala Gly Ile Ser Gly Lys Ser Gln His Thr Arg
             100                 105                 110        
 Pro Val Leu Val Leu Leu Lys Thr Tyr Thr Asn Ser His Ser Phe Xaa
         115                 120                 125            
 Val Lys Gly Leu Gly Trp Glu Phe Ile Leu
     130                 135            



      <210> 2803
      <211> 542
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(542)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2803
 Thr Ala Ala Ala Arg Arg Ser Ser Arg Thr Ser Ser His Arg Ser Leu
   1               5                  10                  15    
 Leu His Val Pro Glu Asn Leu Ala Thr Gly Pro Ser Glu Phe Arg Ser
              20                  25                  30        
 Pro Gly Phe Leu Leu Ser Arg Val Pro Ser Val Trp Asp Pro Thr Glu
          35                  40                  45            
 Asn Arg Thr Val Gln Leu Thr Trp Gln Pro Leu Pro Glu Pro Leu Glu
      50                  55                  60                
 Leu Trp Pro Lys Ala His Leu Thr Asp Ser Phe Pro Asp Leu Leu Gly
  65                  70                  75                  80
 Leu Ala Ala Glu Asp Xaa His Cys Pro Ile Ala Ser Glu Ala Pro Xaa
                  85                  90                  95    
 Thr Ile Thr Asp Ala Glu Leu Arg Val Thr Leu Thr Val Glu Gly Lys
             100                 105                 110        
 Pro Phe Pro Phe Leu Ile Asn Thr Glu Ala Thr His Ser Thr Leu Pro
         115                 120                 125            
 Ser Phe Gln Gly Pro Val Ser Leu Ala Ser Ile Thr Val Val Gly Ile
     130                 135                 140                
 Asp Gly Gln Ala Ser Lys Pro Leu Lys Thr Pro Gln Leu Trp Cys Gln
 145                 150                 155                 160
 Leu Arg Gln Tyr Ser Phe Lys His Ser Phe Leu Val Ile Pro Thr Cys
                 165                 170                 175    
 Pro Val Pro Val Leu Gly Xaa Asp Thr Leu Thr Lys Leu Ser Ala Ser
             180                 185                 190        
 Leu Thr Ile Pro Gly Leu Gln Leu Tyr Leu Ile Ala Ala Leu Leu Pro
         195                 200                 205            
 Asn Pro Lys Pro Pro Leu Arg Pro Pro Leu Val Ser Pro Asp Leu Asn
     210                 215                 220                
 Pro Gln Val Xaa Asp Pro His Ser Cys Pro Pro Glu Asn Lys Pro Pro
 225                 230                 235                 240
 Leu Thr Val Ile Phe Leu Tyr Leu Pro Lys Ser Tyr Lys Thr Ala Pro
                 245                 250                 255    
 Pro His Leu Pro Leu Leu Thr Leu Phe Ser Asp Ser Ala Arg Leu His
             260                 265                 270        
 Pro Gly Glu Ile Asn Ser His Val Ala His Thr Lys Pro Val Trp Trp
         275                 280                 285            
 Ser Leu His Thr Asp Ala His Glu Ile Trp Cys Arg His Ser Asp Arg
     290                 295                 300                
 Gly Thr Ser Leu Gly Arg Ser Ile Pro Cys Pro Pro Ala Leu Cys Ser
 305                 310                 315                 320
 Met Arg Lys Ile His Leu Arg Pro Gln Val Leu Arg Gln Thr Ser Pro
                 325                 330                 335    
 Arg Asn Ile Ser Pro Ile Ser Asn Pro Val Ser Gly Leu Phe Leu Leu
             340                 345                 350        
 Ser Ser Pro Thr Cys Leu Thr Ile Pro Gln Pro Leu Ser Pro Phe Asn
         355                 360                 365            
 Leu Gly Ala Thr Leu Gln Ser Leu Pro Ser Leu Asn Phe Asn Ser Phe
     370                 375                 380                
 His Phe Leu Val Glu Thr Lys Glu Thr Arg Phe Ile Cys Gly Pro Lys
 385                 390                 395                 400
 Thr Pro Ala Leu Val Thr Asp Trp Glu Gly Ser Leu Pro Leu Met Phe
                 405                 410                 415    
 Asn His Cys Arg Asp Thr Ser Leu Ile Ile His Pro Cys Phe Gln Gly
             420                 425                 430        
 Val Arg Pro Cys Arg Asp Ala Cys Leu Ser Pro Ser Pro Leu Ala Ala
         435                 440                 445            
 Ser Pro Ala Phe Leu Gly Lys Gly Gln Val Pro Leu Asn Pro Phe Phe
     450                 455                 460                
 Thr Leu Ser Gly Lys Ser Arg Phe Ser Gly Gly Gly Ala Ser Thr Pro
 465                 470                 475                 480
 Thr Pro Ser Phe His Val Ser Thr Pro Ser Leu Leu Phe Trp Gly Arg
                 485                 490                 495    
 Gly Lys Tyr Pro Ser Thr Pro Ser Ser Pro Leu Val Ala Ser Pro Ala
             500                 505                 510        
 Phe Leu Gly Lys Gly Gln Val Pro Leu Asn Pro Phe Ser Phe Thr Leu
         515                 520                 525            
 Ser Gly Lys Ser His Phe Pro Gly Thr Gly Ala Arg Phe Asn
     530                 535                 540        



      <210> 2804
      <211> 270
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(270)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2804
 Gly Val Ser Pro Cys Trp Pro Gly Trp Ser Arg Thr Pro Asp Phe Gly
   1               5                  10                  15    
 Ser Asn Pro Lys Cys Pro Pro Ile Arg Ala Ser Pro Gly Ala Glu Leu
              20                  25                  30        
 Gln Ala Leu Ser Ser Thr Val Thr Thr Pro Tyr Trp Gly Ile Leu Val
          35                  40                  45            
 Thr Ala Val Phe Pro His Xaa Gly Leu Arg Pro Arg Gln Cys Arg Gln
      50                  55                  60                
 Asp His Pro Ala Gly Arg Gln Gly Pro Gly Pro Gly Glu Val Pro Glu
  65                  70                  75                  80
 Ile Leu Gly Gln Ser Gly Cys Thr Asp Arg Thr Trp Ser Lys Ala Gly
                  85                  90                  95    
 Gly Arg Thr Gln Ala Pro Gly Pro Arg Ser Arg Ala Gly Arg Arg Val
             100                 105                 110        
 Ser Gly Gln Glu Ile Arg Ala Pro Gly Pro Leu Gly Cys Arg His Gly
         115                 120                 125            
 Gly Val Gly Ala Pro Trp Thr Pro Glu Ala Ala Ser Pro Leu Thr Ala
     130                 135                 140                
 Thr Glu Pro Ser Cys Pro His Leu Gln Ala Pro Cys Gly Tyr Met Pro
 145                 150                 155                 160
 Leu Ser Val Ser Pro Arg Arg Arg Tyr Arg Gly Pro Ala Gly Asp Gln
                 165                 170                 175    
 Lys Val Lys Met Leu Lys Phe Lys Ala Phe Cys Leu Asp Tyr Trp Gln
             180                 185                 190        
 Phe Leu Cys Leu Gln Pro Leu His Gly Ala Tyr Lys Arg Asp Ser Asp
         195                 200                 205            
 Leu Met Thr Trp Ile Trp Gly Leu Leu Pro Glu Val Thr Gly Ala Ala
     210                 215                 220                
 Gly Thr Thr Ser Pro Asn Val His Thr Ser Gly Arg Phe Phe Arg Ala
 225                 230                 235                 240
 Cys Val Phe Cys Pro Val His Thr Leu Val Lys Lys Glu Pro His Pro
                 245                 250                 255    
 Gly Gln Gln Glu Ile Ile Met Glu Pro Ser Pro Trp Ser Pro
             260                 265                 270



      <210> 2805
      <211> 134
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(134)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2805
 Phe Glu Pro Leu Phe Tyr Leu Met Cys Leu Leu Asn Leu Phe Pro Leu
   1               5                  10                  15    
 Gln Leu Pro Arg His Pro Phe Leu Phe Leu Thr Val Asp Leu Val Asn
              20                  25                  30        
 Thr Trp Gly Cys Pro Leu Pro Ser Ser Pro Gln Xaa Glu Trp Leu Leu
          35                  40                  45            
 Ala Ala Pro His Arg Ser Thr Pro Pro Pro Leu Ser Ser Gly Phe Pro
      50                  55                  60                
 Ala Arg Arg Gln Leu Glu Pro Gly Ala Gly Ala Arg Gly Pro His His
  65                  70                  75                  80
 Thr Gln Ala Leu His Leu Ser Phe Phe Phe Val Phe Leu Arg Arg Ser
                  85                  90                  95    
 Leu Asp Ser Val Ala Gln Ala Gly Val Gln Trp Arg Gly Leu Gly Ser
             100                 105                 110        
 Leu Gln Pro Leu Pro Pro Gly Phe Val Ile Leu Ser Ser Pro Leu Ser
         115                 120                 125            
 Leu Pro Ser Leu Thr Tyr
     130                



      <210> 2806
      <211> 1600
      <212> PRT
      <213> Homo sapiens


      <400> 2806
 Lys Arg Leu Glu Asn Ile Gln Lys Thr Leu Glu Val Ala Phe Ser Glu
   1               5                  10                  15    
 Ala Val Trp Met Gln Pro Ser Val Val Leu Leu Asp Asp Leu Asp Leu
              20                  25                  30        
 Ile Ala Gly Leu Pro Ala Val Pro Glu His Glu His Ser Pro Asp Ala
          35                  40                  45            
 Val Gln Ser Gln Arg Leu Ala His Ala Leu Asn Asp Met Ile Lys Glu
      50                  55                  60                
 Phe Ile Ser Met Gly Ser Leu Val Ala Leu Ile Ala Thr Ser Gln Ser
  65                  70                  75                  80
 Gln Gln Ser Leu His Pro Leu Leu Val Ser Ala Gln Gly Val His Ile
                  85                  90                  95    
 Phe Gln Cys Val Gln His Ile Gln Pro Pro Asn Gln Glu Gln Arg Cys
             100                 105                 110        
 Glu Ile Leu Cys Asn Val Ile Lys Asn Lys Leu Asp Cys Asp Ile Asn
         115                 120                 125            
 Lys Phe Thr Asp Leu Asp Leu Gln His Val Ala Lys Glu Thr Gly Gly
     130                 135                 140                
 Phe Val Ala Arg Asp Phe Thr Val Leu Val Asp Arg Ala Ile His Ser
 145                 150                 155                 160
 Arg Leu Ser Arg Gln Ser Ile Ser Thr Arg Glu Lys Leu Val Leu Thr
                 165                 170                 175    
 Thr Leu Asp Phe Gln Lys Ala Leu Arg Gly Phe Leu Pro Ala Ser Leu
             180                 185                 190        
 Arg Ser Val Asn Leu His Lys Pro Arg Asp Leu Gly Trp Asp Lys Ile
         195                 200                 205            
 Gly Gly Leu His Glu Val Arg Gln Ile Leu Met Asp Thr Ile Gln Leu
     210                 215                 220                
 Pro Ala Lys Tyr Pro Glu Leu Phe Ala Asn Leu Pro Ile Arg Gln Arg
 225                 230                 235                 240
 Thr Gly Ile Leu Leu Tyr Gly Pro Pro Gly Thr Gly Lys Thr Leu Leu
                 245                 250                 255    
 Ala Gly Val Ile Ala Arg Glu Ser Arg Met Asn Phe Ile Ser Val Lys
             260                 265                 270        
 Gly Pro Glu Leu Leu Ser Lys Tyr Ile Gly Ala Ser Glu Gln Ala Val
         275                 280                 285            
 Arg Asp Ile Phe Ile Arg Ala Gln Ala Ala Lys Pro Cys Ile Leu Phe
     290                 295                 300                
 Phe Asp Glu Phe Glu Ser Ile Ala Pro Arg Arg Gly His Asp Asn Thr
 305                 310                 315                 320
 Gly Val Thr Asp Arg Val Val Asn Gln Leu Leu Thr Gln Leu Asp Gly
                 325                 330                 335    
 Val Glu Gly Leu Gln Gly Val Tyr Val Leu Ala Ala Thr Ser Arg Pro
             340                 345                 350        
 Asp Leu Ile Asp Pro Ala Leu Leu Arg Pro Gly Arg Leu Asp Lys Cys
         355                 360                 365            
 Val Tyr Cys Pro Pro Pro Asp Gln Asp Gly Ser Ser Ser Ser Asp Ser
     370                 375                 380                
 Asp Leu Ser Leu Ser Ser Met Val Phe Leu Asn His Ser Ser Gly Ser
 385                 390                 395                 400
 Asp Asp Ser Ala Gly Asp Gly Glu Cys Gly Leu Asp Gln Ser Leu Val
                 405                 410                 415    
 Ser Leu Glu Met Ser Glu Ile Leu Pro Asp Glu Ser Lys Phe Asn Met
             420                 425                 430        
 Tyr Arg Leu Tyr Phe Gly Ser Ser Tyr Glu Ser Glu Leu Gly Asn Gly
         435                 440                 445            
 Thr Ser Ser Asp Leu Glu Asp Glu Ser Met Asn Gln Pro Gly Pro Ile
     450                 455                 460                
 Lys Thr Arg Leu Ala Ile Ser Gln Ser His Leu Met Thr Ala Leu Gly
 465                 470                 475                 480
 His Thr Arg Pro Ser Ile Ser Glu Asp Asp Trp Lys Asn Phe Ala Glu
                 485                 490                 495    
 Leu Tyr Glu Ser Phe Gln Asn Pro Lys Arg Arg Lys Asn Gln Ser Gly
             500                 505                 510        
 Thr Met Phe Arg Pro Gly Gln Lys Phe Phe Asp Glu Ile Thr Glu Leu
         515                 520                 525            
 Thr Tyr Leu Pro Ser Phe His His Lys Ala Ala Pro His Gln Ala Glu
     530                 535                 540                
 Pro Gly Pro Asn Ser Ser Ser Ala Ser Ala Pro Pro Pro Tyr Asn Pro
 545                 550                 555                 560
 Phe Ile Thr Ser Ser Pro His Thr Gln Ser Gly Leu Gln Phe Arg Ser
                 565                 570                 575    
 Val Thr Ser Pro Pro Pro Ser Ala Gln Gln Phe Pro Leu Lys Glu Val
             580                 585                 590        
 Ala Gly Ala Lys Gly Ile Val Lys Thr Ala Leu Glu Thr Ala Pro Thr
         595                 600                 605            
 Leu Ala Leu Pro Val Ser Ser Gln Pro Phe Ser Leu His Thr Ala Glu
     610                 615                 620                
 Val Gln Gly Cys Ala Val Gly Ile Leu Thr Gln Gly Pro Gly Pro Cys
 625                 630                 635                 640
 Pro Val Ala Phe Leu Ser Lys Gln Leu Asp Leu Thr Val Leu Gly Ser
                 645                 650                 655    
 Pro Ser Cys Leu His Ala Val Ala Ser Ala Ala Leu Ile Leu Leu Glu
             660                 665                 670        
 Ala Leu Lys Ile Thr Asn Tyr Ala Gln Leu Thr Leu Tyr Ser Ser His
         675                 680                 685            
 Asn Phe Gln Asn Leu Phe Ser Phe Ser His Leu Thr His Ile Leu Ser
     690                 695                 700                
 Ala Pro Arg Leu Leu Gln Leu Tyr Ser Leu Phe Val Glu Ser Pro Thr
 705                 710                 715                 720
 Ile Thr Ile Leu Pro Gly Pro Asp Phe Asn Leu Ala Ser His Ile Ile
                 725                 730                 735    
 Leu Asp Thr Thr Pro Asp Pro Asp Asp Cys Met Ser Leu Ile Tyr Leu
             740                 745                 750        
 Thr Phe Thr Pro Phe Pro His Ile Ser Phe Phe Ser Val Pro His Val
         755                 760                 765            
 Asp His Ile Trp Phe Thr Asp Gly Ser Ser Thr Arg Pro Asp Arg His
     770                 775                 780                
 Ser Pro Ala Lys Ala Gly Tyr Ala Ile Glu Ser Ser Thr Ser Ile Ile
 785                 790                 795                 800
 Glu Ala Thr Ala Leu Pro Pro Ser Thr Thr Ser Gln Gln Ala Glu Leu
                 805                 810                 815    
 Ile Ala Leu Thr Arg Ala Phe Thr Leu Ala Lys Gly Leu His Val Asn
             820                 825                 830        
 Ile Tyr Thr Asp Ser Lys Tyr Ala Phe His Ile Leu His His His Ala
         835                 840                 845            
 Val Ile Trp Ala Glu Arg Gly Phe Leu Thr Thr Gln Gly Ser Ser Ile
     850                 855                 860                
 Ile Asn Ala Ser Leu Ile Lys Thr Leu Leu Lys Ala Ala Leu Leu Pro
 865                 870                 875                 880
 Lys Glu Ala Gly Val Thr His Cys Lys Gly His Gln Lys Ala Ser Asp
                 885                 890                 895    
 Pro Ile Thr Leu Gly Asn Ala Tyr Ala Asp Lys Asp Arg Thr Ile Asp
             900                 905                 910        
 Gly Ser Ser Gln Val Ile Glu Glu Lys Asn His Asn Gly Tyr Ser Val
         915                 920                 925            
 Ile Asp Thr Gly Thr Leu Val Glu Ala Glu Leu Glu Lys Leu Pro Asn
     930                 935                 940                
 Asn Trp Ser Pro Gln Thr Cys Glu Leu Phe Ala Leu Ser Gln Ala Leu
 945                 950                 955                 960
 Lys Tyr Leu Gln Asn Gln Lys Thr Ile Ser Ile Leu Ile Gln Lys Glu
                 965                 970                 975    
 Pro Ser Pro Ala Leu Gly Leu Thr Pro Glu Arg Lys Gly Asn Val Gly
             980                 985                 990        
 His Ala Gly Lys Gly Pro Leu Glu Ser Ser Ser Pro Asp Pro Phe Leu
         995                1000                1005            
 Cys Gly Gln Glu Arg Arg Glu Lys Gly Cys Arg Thr Ala Thr Ser Val
    1010                1015                1020                
 Ser Ile Thr Asn Pro Ile Asn Arg Gly Pro Trp Val Val Thr His Pro
1025                1030                1035                1040
 Gly Lys Glu Leu Thr Pro Glu His Lys Gly Asn Val Gly His Ala Gly
                1045                1050                1055    
 Arg Asp Ile Leu Ala Lys Ala Gly Ala Ile Ile His Leu Asn Ile Gly
            1060                1065                1070        
 Glu Gly Thr Pro Val Cys Cys Pro Leu Leu Glu Glu Gly Ile Asn Pro
        1075                1080                1085            
 Glu Val Trp Ala Thr Glu Gly Gln Tyr Gly Arg Ala Lys Asn Ala Arg
    1090                1095                1100                
 Pro Val Gln Val Lys Leu Lys Asp Ser Thr Ser Phe Pro Tyr Gln Arg
1105                1110                1115                1120
 Gln Tyr Pro Leu Arg Pro Lys Ala Gln Gln Gly Leu Gln Lys Ile Val
                1125                1130                1135    
 Lys Asp Leu Lys Ala Gln Gly Leu Val Lys Pro Cys Ser Asn Pro Cys
            1140                1145                1150        
 Ser Thr Pro Ile Leu Gly Val Gln Lys Pro Asn Arg Gln Trp Arg Thr
        1155                1160                1165            
 Leu Cys His Gln Ala Thr Gln Ala Leu Phe Asn Phe Leu Ala Thr Cys
    1170                1175                1180                
 Gly Tyr Met Val Ser Lys Pro Lys Ala Gln Leu Cys Ser Gln Gln Arg
1185                1190                1195                1200
 Tyr Leu Gly Leu Lys Leu Ser Lys Gly Thr Arg Ala Leu Ser Glu Glu
                1205                1210                1215    
 His Ile Gln Pro Ile Leu Ala Tyr Pro His Pro Lys Thr Leu Lys Gln
            1220                1225                1230        
 Leu Arg Gly Phe Leu Gly Val Ile Gly Phe Cys Arg Lys Trp Ile Pro
        1235                1240                1245            
 Arg Tyr Gly Glu Ile Ala Arg Ser Leu Asn Thr Leu Ile Lys Glu Thr
    1250                1255                1260                
 Gln Lys Ala Asn Thr His Leu Val Arg Trp Thr Thr Glu Val Glu Val
1265                1270                1275                1280
 Ala Phe Gln Ala Leu Thr Gln Ala Pro Val Leu Ser Leu Pro Thr Gly
                1285                1290                1295    
 Gln Asp Phe Ser Ser Tyr Val Thr Glu Lys Thr Gly Ile Ala Leu Gly
            1300                1305                1310        
 Val Leu Thr Gln Ile Arg Gly Met Ser Leu Gln Pro Val Ala Tyr Leu
        1315                1320                1325            
 Thr Lys Glu Ile Asp Val Val Ala Lys Val Val Ala Val Ala Val Leu
    1330                1335                1340                
 Val Ser Glu Ala Val Lys Ile Ile Gln Gly Arg Asp Leu Thr Val Trp
1345                1350                1355                1360
 Thr Ser His Asp Val Asn Gly Ile Leu Thr Ala Lys Gly Asp Leu Trp
                1365                1370                1375    
 Leu Ser Asp Asn Cys Leu Leu Lys Cys Gln Ala Leu Leu Leu Glu Gly
            1380                1385                1390        
 Pro Val Leu Arg Leu Cys Thr Cys Ala Thr Leu Asn Pro Ala Thr Phe
        1395                1400                1405            
 Leu Pro Asp Asn Glu Glu Lys Ile Lys His Asn Cys Gln Gln Val Ile
    1410                1415                1420                
 Ser Gln Thr Tyr Ala Thr Arg Gly Asp Leu Leu Glu Val Pro Leu Thr
1425                1430                1435                1440
 Asp Pro Asp Leu Asn Leu Tyr Thr Asp Gly Ser Ser Phe Val Glu Lys
                1445                1450                1455    
 Gly Leu Arg Lys Val Gly Tyr Ala Val Val Ser Asp Asn Gly Ile Leu
            1460                1465                1470        
 Glu Ser Asn Pro Leu Thr Pro Gly Thr Ser Ala Gln Leu Ala Glu Leu
        1475                1480                1485            
 Ile Ala Leu Thr Trp Ala Leu Glu Leu Gly Glu Glu Lys Arg Ala Asn
    1490                1495                1500                
 Ile Tyr Thr Asp Ser Lys Tyr Ala Tyr Leu Val Leu His Ala His Ala
1505                1510                1515                1520
 Ala Ile Trp Lys Glu Arg Glu Phe Leu Thr Ser Glu Arg Thr Pro Ile
                1525                1530                1535    
 Lys His Gln Glu Ala Ile Arg Lys Leu Leu Leu Ala Val Gln Lys Pro
            1540                1545                1550        
 Lys Glu Val Ala Val Leu His Cys Arg Gly His Gln Lys Gly Lys Glu
        1555                1560                1565            
 Arg Glu Ile Glu Glu Asn Cys Gln Ala Asp Ile Glu Ala Lys Arg Ala
    1570                1575                1580                
 Ala Arg Gln Asp Pro Pro Leu Glu Met Leu Ile Lys Gln Pro Leu Val
1585                1590                1595                1600





      <210> 2807
      <211> 197
      <212> PRT
      <213> Homo sapiens


      <400> 2807
 Met Thr Pro Arg Gly Thr Gly Gly Asp Ser Glu Val Pro Phe Gln Ala
   1               5                  10                  15    
 Ala Lys Pro Leu Ser Val Lys Gln Gly Val Ser Phe Arg Leu Trp Ala
              20                  25                  30        
 Arg Arg Arg Pro Arg Cys Asp Phe Leu Arg Ser Ser Arg Ile Arg Val
          35                  40                  45            
 His Pro Thr Pro Ala Ala Ser Thr Met Pro Pro Lys Phe Asp Pro Asn
      50                  55                  60                
 Glu Ile Lys Val Val Tyr Leu Arg Cys Thr Gly Gly Glu Val Gly Ala
  65                  70                  75                  80
 Thr Ser Ala Leu Ala Pro Lys Ile Gly Pro Leu Cys Leu Ser Pro Lys
                  85                  90                  95    
 Lys Asn Arg Gln Ala Gln Ile Glu Val Val Pro Ser Ala Ser Ala Leu
             100                 105                 110        
 Ile Ile Lys Ala Leu Lys Glu Pro Pro Arg Asp Arg Lys Lys Gln Lys
         115                 120                 125            
 Asn Ile Lys His Ser Gly Asn Ile Thr Phe Asp Glu Ile Val Asn Ile
     130                 135                 140                
 Ala Arg Gln Met Arg His Arg Ser Leu Ala Arg Glu Leu Ser Gly Thr
 145                 150                 155                 160
 Ile Lys Glu Ile Leu Gly Thr Ala Gln Ser Val Gly Cys Asn Val Asp
                 165                 170                 175    
 Gly Arg His Pro His Asp Ile Ile Asp Asp Ile Asn Ser Gly Ala Val
             180                 185                 190        
 Glu Cys Pro Ala Ser
         195        



      <210> 2808
      <211> 203
      <212> PRT
      <213> Homo sapiens


      <400> 2808
 Ile Gly Cys Asp Val Leu Ile Asn Asn Ala Gly Ile Phe Gln Cys Pro
   1               5                  10                  15    
 Tyr Met Lys Thr Glu Asp Gly Phe Glu Met Gln Phe Gly Val Asn His
              20                  25                  30        
 Leu Gly His Phe Leu Leu Thr Asn Leu Leu Leu Gly Leu Leu Lys Ser
          35                  40                  45            
 Ser Ala Pro Ser Arg Ile Val Val Val Ser Ser Lys Leu Tyr Lys Tyr
      50                  55                  60                
 Gly Asp Ile Asn Phe Asp Asp Leu Asn Ser Glu Gln Ser Tyr Asn Lys
  65                  70                  75                  80
 Ser Phe Cys Tyr Ser Arg Ser Lys Leu Ala Asn Ile Leu Phe Thr Arg
                  85                  90                  95    
 Glu Leu Ala Arg Arg Leu Glu Gly Thr Asn Val Thr Val Asn Val Leu
             100                 105                 110        
 His Pro Gly Ile Val Arg Thr Asn Leu Gly Arg His Asn Thr Phe His
         115                 120                 125            
 Cys Trp Ser Asn His Ser Ser Ile Trp Trp Ser Trp Ala Phe Phe Lys
     130                 135                 140                
 Thr Pro Val Glu Gly Ala Gln Thr Ser Ile Tyr Leu Ala Ser Ser Pro
 145                 150                 155                 160
 Glu Val Glu Gly Val Ser Gly Arg Tyr Phe Gly Asp Cys Lys Glu Glu
                 165                 170                 175    
 Glu Leu Leu Pro Lys Ala Met Asp Glu Ser Val Ala Arg Lys Leu Trp
             180                 185                 190        
 Asp Ile Ser Glu Val Met Val Gly Leu Leu Lys
         195                 200            



      <210> 2809
      <211> 68
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(68)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2809
 His Ile Trp Gln Asn Ser Leu Ile Val Leu Phe Arg Gly Cys Arg Ser
   1               5                  10                  15    
 Ala His Ala Lys Val His Arg Trp Lys Asn Xaa Leu Pro Leu Asn Leu
              20                  25                  30        
 Ala Pro Leu Leu Pro Arg Ser Gly Ser Ser Ala Pro Ile Arg Pro Pro
          35                  40                  45            
 Pro Ser Ala Gln Ala Arg Gln Pro Met Lys Ser Thr Tyr Gly Val Asp
      50                  55                  60                
 Arg Arg His Ser
  65            



      <210> 2810
      <211> 73
      <212> PRT
      <213> Homo sapiens


      <400> 2810
 Met Leu Leu Leu Ser Ser Ser Leu Leu Lys Cys Gly Thr Cys Gln Trp
   1               5                  10                  15    
 Gln Val Gln Pro Ala Val Ala Gly Ser Leu Glu Gly Gly Glu Glu Glu
              20                  25                  30        
 Ser Met Val Ser Ala Leu Leu Ile Ser Ala Leu Pro Phe Leu Gly Thr
          35                  40                  45            
 Ser His Val Thr Val Glu Thr Leu Asp Val Gln Tyr Thr Val Phe Pro
      50                  55                  60                
 Lys Leu Ile Cys Phe Leu Pro Cys Glu
  65                  70            



      <210> 2811
      <211> 118
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(118)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2811
 Phe Gly Phe Asn Gly Cys Ser Lys Arg Ile Ile Lys Leu Gln Glu Leu
   1               5                  10                  15    
 Ser Asp Leu Glu Glu Arg Glu Asn Glu Asp Ser Met Val Pro Leu Pro
              20                  25                  30        
 Lys Gln Ser Leu Lys Phe Phe Cys Ala Leu Glu Val Val Leu Pro Ser
          35                  40                  45            
 Cys Asp Cys Arg Ser Pro Gly Ile Gly Leu Val Glu Glu Pro Met Asp
      50                  55                  60                
 Lys Val Glu Glu Gly Pro Leu Ser Phe Leu Met Lys Arg Lys Thr Ala
  65                  70                  75                  80
 Gln Lys Leu Ala Ile Gln Lys Ala Leu Ser Asp Ala Phe Gln Lys Leu
                  85                  90                  95    
 Leu Ile Val Val Leu Gly Gln Asp Cys Leu Asp His Pro Xaa Ser Thr
             100                 105                 110        
 Ser Val Ser Val Ser Lys
         115            



      <210> 2812
      <211> 971
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(971)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2812
 Arg Thr Arg Ser Leu Thr Arg Lys Ala Met Ala Glu His Ala Pro Arg
   1               5                  10                  15    
 Arg Cys Cys Leu Gly Trp Asp Phe Ser Thr Gln Gln Val Lys Val Val
              20                  25                  30        
 Ala Val Asp Ala Glu Leu Asn Val Phe Tyr Glu Glu Ser Val His Phe
          35                  40                  45            
 Asp Arg Asp Leu Pro Glu Phe Gly His Val Leu Asp Val His Gly Val
      50                  55                  60                
 His Val His Lys Asp Gly Leu Thr Val Thr Ser Pro Val Leu Met Trp
  65                  70                  75                  80
 Val Gln Ala Leu Asp Ile Ile Leu Glu Lys Met Lys Ala Ser Gly Phe
                  85                  90                  95    
 Glu Phe Ser Gln Val Leu Ala Leu Ser Gly Ala Gly Gln Gln His Gly
             100                 105                 110        
 Ser Ile Tyr Trp Lys Ala Gly Ala Gln Gln Ala Leu Thr Ser Leu Ser
         115                 120                 125            
 Pro Asp Leu Arg Leu His Gln Gln Leu Gln Asp Cys Phe Ser Ile Ser
     130                 135                 140                
 Asp Cys Pro Val Trp Met Asp Ser Ser Thr Thr Ala Gln Cys Arg Gln
 145                 150                 155                 160
 Leu Glu Ala Ala Val Gly Gly Ala Gln Ala Leu Ser Cys Leu Thr Gly
                 165                 170                 175    
 Ser Arg Ala Tyr Glu Phe Asn Leu Val Cys Asp Arg Lys His Leu Lys
             180                 185                 190        
 Asp Thr Thr Gln Ser Val Phe Met Ala Gly Leu Leu Val Gly Thr Leu
         195                 200                 205            
 Met Phe Gly Pro Leu Cys Asp Arg Ile Gly Arg Lys Ala Thr Ile Leu
     210                 215                 220                
 Ala Gln Leu Leu Leu Phe Thr Leu Ile Gly Leu Ala Thr Ala Phe Val
 225                 230                 235                 240
 Pro Ser Phe Glu Leu Tyr Met Ala Leu Arg Phe Ala Gly Leu Leu Pro
                 245                 250                 255    
 Ser Leu Asp Leu Ala Ser Ala Met Ser Pro Tyr Xaa Gln Asn Gly Trp
             260                 265                 270        
 Gly Pro His Gly Gly Arg Arg Pro Trp Ser Trp Pro Ser Ala Thr Ser
         275                 280                 285            
 Pro Ser Gly Arg Trp Cys Leu Arg Asp Ser Pro Thr Val Ser Ala Thr
     290                 295                 300                
 Gly Gly Ser Phe Arg Ser Pro Ala Leu Arg Leu Ala Tyr Cys Ser Ser
 305                 310                 315                 320
 Leu Leu Leu Gly Ser Ala Arg Ile Cys Thr Leu Ala Pro Asp Pro Trp
                 325                 330                 335    
 Glu Asp Gly Arg Gly Asp Thr Thr Asp Pro Glu Asn Gly Leu Gly Gln
             340                 345                 350        
 Xaa Ala Glu Thr Leu Pro Gly Ala His Glu Pro Ala Gly Pro Arg Glu
         355                 360                 365            
 Asp Arg Pro Leu Arg Glu Cys Pro Gly Ser Val Gln Thr Pro Pro Ala
     370                 375                 380                
 Pro Glu Gly Asp Pro Asp Tyr Leu Leu Cys Leu Val Cys Gly Gln Ser
 385                 390                 395                 400
 Gly Val Leu Arg Pro Glu Pro Pro Ser Gly Gly Leu Arg Pro Gly Arg
                 405                 410                 415    
 Leu Ser Asp Ala Ala His Leu Trp Ser Cys Xaa Gly Ala Cys Pro Leu
             420                 425                 430        
 Phe Gln His Leu His Asp Ala Glu Val Trp Pro Gln Val Glu Pro Arg
         435                 440                 445            
 Trp Gly Pro Trp Ser Trp Val Ala Xaa Cys Val Ser Ser Ser Ser Ser
     450                 455                 460                
 Ser Gln Gln Ile Cys Pro Trp Trp Ser Pro Cys Trp Leu Trp Trp Gly
 465                 470                 475                 480
 Lys Trp Pro Gln Leu Leu Pro Leu Pro Ser Pro Met Cys Thr Leu Pro
                 485                 490                 495    
 Ser Phe Ser Pro Pro Ser Ser Gly Arg Gln Ala Trp Gly Trp Trp Ala
             500                 505                 510        
 Ser Ser His Gly Ser Gly Ala Ser Ser His His Leu Xaa Ser Cys Trp
         515                 520                 525            
 Glu Ser Thr Thr Leu Pro Ser Pro Cys Ser Ser Thr Ala Ala Ser Pro
     530                 535                 540                
 Ser Trp Pro Ala Ser Leu Cys Thr Leu Leu Pro Glu Thr His Gly Gln
 545                 550                 555                 560
 Gly Leu Lys Asp Thr Leu Gln Asp Leu Glu Leu Gly Pro His Pro Arg
                 565                 570                 575    
 Ser Pro Lys Ser Val Pro Ser Glu Lys Glu Thr Glu Ala Lys Gly Arg
             580                 585                 590        
 Thr Ser Ser Pro Gly Val Ala Phe Val Ser Leu Gly Thr Ser Asp Thr
         595                 600                 605            
 Leu Phe Leu Trp Leu Gln Glu Pro Met Pro Ala Leu Glu Gly His Ile
     610                 615                 620                
 Phe Cys Asn Pro Val Asp Ser Gln His Tyr Met Ala Leu Leu Cys Phe
 625                 630                 635                 640
 Lys Asn Gly Ser Leu Met Arg Glu Lys Ile Arg Asn Glu Ser Val Ser
                 645                 650                 655    
 Arg Ser Trp Ser Asp Phe Ser Lys Ala Leu Gln Ser Thr Glu Met Gly
             660                 665                 670        
 Asn Gly Gly Asn Leu Gly Phe Tyr Phe Asp Val Met Glu Ile Thr Pro
         675                 680                 685            
 Glu Ile Ile Gly Arg His Arg Phe Asn Thr Glu Asn His Lys Tyr Phe
     690                 695                 700                
 Lys Gly Lys Gly Ala Pro Gly His Pro Met Pro Ser Leu Lys Ala Asn
 705                 710                 715                 720
 Phe Asp Leu Leu Ala Cys Leu Arg Gly Val Gly Ser Ser Thr Leu Leu
                 725                 730                 735    
 Leu Trp Pro Ala Val Leu Gly Ala Gln Thr Arg Gln Ala Gly Val Asn
             740                 745                 750        
 Glu Gly Arg Ser Gln Val Ala Asp Phe Leu Arg Ile Pro Val Thr Gly
         755                 760                 765            
 Cys Pro Glu Gln Arg Arg Asn Pro Pro Ser Pro Pro Ala Pro Leu Gly
     770                 775                 780                
 Thr Gly Gly Pro Ala Glu Glu Arg Leu Gln Phe Pro Gly Val Ala Gly
 785                 790                 795                 800
 Ser Arg Arg Gly Arg Gly Arg Ile Leu Arg Ala Gly Gly Ile Gly Arg
                 805                 810                 815    
 Ala Ser Pro Gly Glu Gly Thr Gly Ala Pro Arg Pro Arg Ala Gly Gln
             820                 825                 830        
 Gly Arg Gly Gly Pro Gly Lys Pro Glu Ser Gly Gly Gly Gly Pro Val
         835                 840                 845            
 Ala Leu Arg Pro Gly Asp Cys Thr Cys Cys Val Leu Lys Ser Gln Pro
     850                 855                 860                
 Arg Gln Gln Arg Arg Gly Ala Cys Ser Ala Met Ala Phe Arg Val Arg
 865                 870                 875                 880
 Leu Arg Val Arg Gln Ser Val Arg Pro Pro Arg Gly Val Ile Val Ala
                 885                 890                 895    
 Ala Leu Gln Arg Pro Glu Thr Gln Gly Pro Ala Pro Ser Ser Ala Arg
             900                 905                 910        
 Pro Asp Cys Gly Pro Glu Ser Arg Gly Gly Leu Ala Leu Trp Arg Arg
         915                 920                 925            
 Leu Arg Gly Tyr Ala Ser Arg Asp Arg Val Leu Cys Asn Arg Arg Cys
     930                 935                 940                
 Pro His Ala Ala Arg Phe Pro Ser Lys Arg Thr Pro Ser Gly Ser Pro
 945                 950                 955                 960
 His Leu His Leu Met Ser Ser Trp Ala Val Pro
                 965                 970    



      <210> 2813
      <211> 299
      <212> PRT
      <213> Homo sapiens


      <400> 2813
 Met Thr Tyr Gly Val Gly Lys Gly Asp Met Val Asp Gly Thr Lys Glu
   1               5                  10                  15    
 Arg Gly Glu Arg Ile Glu Ser Ala Leu Gly Thr Ser His Ile Met Arg
              20                  25                  30        
 Val Ala Glu Pro Gln Gly Ser Gln Ser Trp Cys Pro Asp Glu Glu Leu
          35                  40                  45            
 Arg Pro Val Gly Ser Pro Ala Thr Ala Ala Gln Lys Leu Pro Ser Thr
      50                  55                  60                
 Pro Gly Ala Leu Gly Pro Thr His Ser Thr Glu Cys Cys Ser Ile Pro
  65                  70                  75                  80
 Leu Asp Pro Lys Ala Gln Gln Gly Leu Gln Lys Ile Val Lys Asp Leu
                  85                  90                  95    
 Lys Ala Gln Gly Leu Val Lys Pro Cys Asn Ser Pro Cys Asn Thr Pro
             100                 105                 110        
 Ile Leu Gly Val Gln Lys Pro Asn Gly Gln Trp Arg Leu Val Gln Asp
         115                 120                 125            
 Leu Arg Ile Ile Asn Glu Ala Leu Val Pro Leu Tyr Pro Ala Val Pro
     130                 135                 140                
 Asn Pro Tyr Thr Leu Leu Ser Gln Ile Pro Glu Glu Ala Glu Trp Phe
 145                 150                 155                 160
 Thr Val Leu Gly Leu Lys Asp Asp Phe Phe Cys Ile Pro Val His Pro
                 165                 170                 175    
 Asp Ser Gln Phe Leu Phe Ala Phe Glu Glu Pro Ser Asn Pro Thr Ser
             180                 185                 190        
 Gln Leu Thr Trp Thr Val Leu Pro Lys Gly Phe Arg Asp Ser Pro His
         195                 200                 205            
 Leu Phe Gly Gln Val Leu Ala Gln Asn Leu Ser Gln Phe Ser Tyr Leu
     210                 215                 220                
 Asp Thr Leu Val Leu Arg Tyr Val Asp Asp Leu Leu Leu Ala Ala Arg
 225                 230                 235                 240
 Ser Glu Thr Leu Cys His Gln Ala Thr Gln Ala Leu Leu Asn Phe Leu
                 245                 250                 255    
 Thr Thr Cys Gly Tyr Lys Val Ser Lys Pro Lys Ala Gln Leu Cys Ser
             260                 265                 270        
 Gln Glu Val Thr Tyr Leu Gly Leu Lys Leu Ser Lys Gly Thr Arg Ala
         275                 280                 285            
 Leu Ser Glu Glu Arg Ile Gln Pro Ile Leu Ala
     290                 295                



      <210> 2814
      <211> 307
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(307)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2814
 Xaa Pro Ala Glu Ala Leu Lys Asp Gly Glu Glu Arg Gln Lys Asn Lys
   1               5                  10                  15    
 Lys Lys Ala Lys Lys Ile Lys Ala Arg Met Asn Phe Arg Ala Lys Glu
              20                  25                  30        
 Tyr Glu Ser Leu Met Glu Thr Lys Asn Ser Gly Ser Asp Ser Pro Tyr
          35                  40                  45            
 Lys Ala Lys Leu Gln Arg Leu Ala Lys Asp Leu Leu Lys Gln Val Gln
      50                  55                  60                
 Val Gln Asp Ser Gly Ser Trp Ala Asn Asn Lys Val Ser Ala Leu Asp
  65                  70                  75                  80
 Arg Thr Leu Gly Glu Ile Thr Arg Ile Leu Glu Lys Glu Asn Val Ala
                  85                  90                  95    
 Asp Gln Ile Ala Phe Gln Ala Ala Gly Gly Leu Thr Ala Leu Glu His
             100                 105                 110        
 Ile Leu Gln Ala Val Val Pro Ala Thr Asn Val Asn Thr Val Leu Arg
         115                 120                 125            
 Asn Ser Ser Met Pro Gln Asp Ser Tyr Met Gln Cys Val Thr Leu Cys
     130                 135                 140                
 Phe Ala Val Thr Gly Arg Ser Tyr Ser Ile Phe Asp Asn Asn Arg Gln
 145                 150                 155                 160
 Asp Pro Thr Gly Leu Thr Ala Ala Leu Gln Ala Thr Asp Leu Ala Gly
                 165                 170                 175    
 Val Leu His Met Leu Tyr Cys Val Leu Phe His Gly Thr Ile Leu Asp
             180                 185                 190        
 Pro Ser Thr Ala Ser Pro Lys Glu Asn Tyr Thr Gln Asn Thr Ile Gln
         195                 200                 205            
 Val Ala Ile Gln Ser Leu Arg Phe Phe Asn Ser Phe Ala Ala Leu His
     210                 215                 220                
 Leu Pro Ala Phe Gln Ser Ile Val Gly Ala Glu Gly Leu Ser Leu Ala
 225                 230                 235                 240
 Phe Arg His Met Ala Ser Ser Leu Leu Gly His Cys Ser Gln Val Ser
                 245                 250                 255    
 Cys Glu Ser Leu Leu His Glu Val Ile Val Cys Val Gly Tyr Phe Thr
             260                 265                 270        
 Val Asn His Pro Asp Asn Gln Gly Asp Arg Ala Val Arg Pro Pro Pro
         275                 280                 285            
 His Ser Ala Ala Lys Ser Ser Ala Ser Cys Pro Ser Ser Ile Ser Val
     290                 295                 300                
 Thr His Gly
 305        



      <210> 2815
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 2815
 Glu Val Arg Trp Asn Ser Pro Pro Thr Asp Ser Leu Ser Pro Asp Gly
   1               5                  10                  15    
 Gly Ser Ile Glu Leu Glu Phe Tyr Leu Ala Pro Glu Pro Phe Ser Met
              20                  25                  30        
 Pro Ser Leu Leu Gly Ala Pro Pro Tyr Ser Gly Leu Gly Gly Val Gly
          35                  40                  45            
 Asp Pro Tyr Ala Pro Leu Met Val Leu Met Cys Arg Val Cys Leu Glu
      50                  55                  60                
 Asp Lys Pro Ile Lys Pro Leu Pro Cys Cys Lys Lys Ala Val Cys Glu
  65                  70                  75                  80
 Glu Cys Leu Lys Val Tyr Leu Ser Ala Gln Ile Gln Cys Pro Thr Cys
                  85                  90                  95    
 Gln Phe Val Trp Cys Phe Lys Cys His Ser Pro Trp His Glu Gly Val
             100                 105                 110        
 Asn Cys Lys Glu Tyr Lys Lys Gly Asp Lys Leu Leu Arg His Trp Ala
         115                 120                 125            
 Ser Glu Ile Glu His Gly Gln Arg Asn Ala Gln Lys Cys Pro Lys Cys
     130                 135                 140                
 Lys Ile His Ile Gln Arg Thr Glu Gly Cys Asp His Met
 145                 150                 155        



      <210> 2816
      <211> 428
      <212> PRT
      <213> Homo sapiens


      <400> 2816
 Arg Gly Ala Val Phe Pro Gly Pro Glu His Ser Val Pro Glu Glu Ser
   1               5                  10                  15    
 Val Thr Phe Glu Asp Val Ala Val Val Phe Thr Asp Glu Glu Trp Ser
              20                  25                  30        
 Arg Leu Val Pro Ile Gln Arg Asp Leu Tyr Lys Glu Val Met Leu Glu
          35                  40                  45            
 Asn Tyr Asn Ser Ile Val Ser Leu Gly Leu Pro Val Pro Gln Pro Asp
      50                  55                  60                
 Val Ile Phe Gln Leu Lys Arg Gly Asp Lys Pro Trp Met Val Asp Leu
  65                  70                  75                  80
 His Gly Ser Glu Glu Arg Glu Trp Pro Glu Ser Val Ser Leu Asp Trp
                  85                  90                  95    
 Glu Thr Lys Pro Glu Ile His Asp Ala Ser Asp Lys Lys Ser Glu Gly
             100                 105                 110        
 Ser Leu Arg Glu Cys Leu Gly Arg Gln Ser Pro Leu Cys Pro Lys Phe
         115                 120                 125            
 Glu Val His Thr Pro Asn Gly Arg Met Gly Thr Glu Lys Gln Ser Pro
     130                 135                 140                
 Ser Gly Glu Thr Arg Lys Lys Ser Leu Ser Arg Asp Lys Gly Leu Arg
 145                 150                 155                 160
 Arg Arg Ser Ala Leu Ser Arg Glu Ile Leu Thr Lys Glu Arg His Gln
                 165                 170                 175    
 Glu Cys Ser Asp Cys Gly Lys Thr Phe Phe Asp His Ser Ser Leu Thr
             180                 185                 190        
 Arg His Gln Arg Thr His Thr Gly Glu Lys Pro Tyr Asp Cys Arg Glu
         195                 200                 205            
 Cys Gly Lys Ala Phe Ser His Arg Ser Ser Leu Ser Arg His Leu Met
     210                 215                 220                
 Ser His Thr Gly Glu Ser Pro Tyr Glu Cys Ser Val Cys Ser Lys Ala
 225                 230                 235                 240
 Phe Phe Asp Arg Ser Ser Leu Thr Val His Gln Arg Ile His Thr Gly
                 245                 250                 255    
 Glu Lys Pro Phe Gln Cys Asn Glu Cys Gly Lys Ala Phe Phe Asp Arg
             260                 265                 270        
 Ser Ser Leu Thr Arg His Gln Arg Ile His Thr Gly Glu Ser Pro Tyr
         275                 280                 285            
 Glu Cys His Gln Cys Gly Lys Ala Phe Ser Gln Lys Ser Ile Leu Thr
     290                 295                 300                
 Arg His Gln Leu Ile His Thr Gly Arg Lys Pro Tyr Glu Cys Asn Glu
 305                 310                 315                 320
 Cys Gly Lys Ala Phe Tyr Gly Val Ser Ser Leu Asn Arg His Gln Lys
                 325                 330                 335    
 Ala His Ala Gly Asp Pro Arg Tyr Gln Cys Asn Glu Cys Gly Lys Ala
             340                 345                 350        
 Phe Phe Asp Arg Ser Ser Leu Thr Gln His Gln Lys Ile His Thr Gly
         355                 360                 365            
 Asp Lys Pro Tyr Glu Cys Ser Glu Cys Gly Lys Ala Phe Ser Gln Arg
     370                 375                 380                
 Cys Arg Leu Thr Arg His Gln Arg Val His Thr Gly Glu Lys Pro Phe
 385                 390                 395                 400
 Glu Cys Thr Val Cys Gly Lys Val Phe Ser Ser Lys Ser Ser Val Ile
                 405                 410                 415    
 Gln His Gln Arg Arg Tyr Ala Lys Gln Gly Ile Asp
             420                 425            



      <210> 2817
      <211> 53
      <212> PRT
      <213> Homo sapiens


      <400> 2817
 Met Leu Tyr Ile Glu Cys Lys Ser His Lys Leu Val Ala Pro Leu Ala
   1               5                  10                  15    
 Val Phe Phe Ala Leu Phe Phe Leu Leu Ile Phe Phe Trp Val Ala Phe
              20                  25                  30        
 Ser Tyr Pro Phe Glu Leu Leu Phe Leu Gln Leu Arg Ser Arg Gln Ala
          35                  40                  45            
 Asp Ile Gly Val Gln
      50            



      <210> 2818
      <211> 177
      <212> PRT
      <213> Homo sapiens


      <400> 2818
 Thr Gly Thr Ile Asp Lys Leu Gln Gly Ser Gly Pro His Leu Leu Arg
   1               5                  10                  15    
 Asp Trp Ala Phe His Pro Pro Trp Arg Lys Ile Cys Leu His Cys Lys
              20                  25                  30        
 Cys Pro Gln Glu Glu His Met Val Thr Val Met Pro Leu Glu Met Glu
          35                  40                  45            
 Lys Thr Ile Ser Lys Leu Met Phe Asp Phe Gln Arg Asn Ser Thr Ser
      50                  55                  60                
 Asp Asp Asp Ser Gly Cys Ala Leu Glu Glu Tyr Ala Trp Val Pro Pro
  65                  70                  75                  80
 Gly Leu Lys Pro Glu Gln Val His Gln Tyr Tyr Ser Cys Leu Pro Glu
                  85                  90                  95    
 Glu Lys Val Pro Tyr Val Asn Ser Pro Gly Glu Lys Leu Arg Ile Lys
             100                 105                 110        
 Gln Leu Leu His Gln Leu Pro Pro His Asp Asn Glu Val Arg Tyr Cys
         115                 120                 125            
 Asn Ser Leu Asp Glu Glu Glu Lys Arg Glu Leu Lys Leu Phe Ser Ser
     130                 135                 140                
 Gln Arg Lys Arg Glu Asn Leu Gly Arg Gly Asn Val Arg Pro Phe Pro
 145                 150                 155                 160
 Val Thr Met Thr Gly Ala Ile Cys Glu Gln Val Ser Met Asp Ser Gly
                 165                 170                 175    
 Tyr
    



      <210> 2819
      <211> 107
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(107)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2819
 Met Trp Leu Glu Pro Met Gln Met Gly Phe Leu His Met Met Glu Lys
   1               5                  10                  15    
 Met Ala Ala Arg Thr Ser Ala Ile Leu Asp Xaa Gly Thr Leu Lys Xaa
              20                  25                  30        
 Phe His Phe Thr Leu Thr Thr Ser Leu Lys Ala Leu Ser Ser His Thr
          35                  40                  45            
 Pro Ile Phe Pro Gly Thr Gly Glu Leu Gln Leu Pro Val Ser Pro Ser
      50                  55                  60                
 Val Cys Leu Asp Gln Gly Met Gln Leu Lys Pro Ser Thr Ser Ser His
  65                  70                  75                  80
 Leu Leu Lys Thr Val Lys Pro Arg Met Lys Arg Gln Ser Leu Leu His
                  85                  90                  95    
 Met Lys Gln Ser Phe Glu Pro Lys Ile Tyr Leu
             100                 105        



      <210> 2820
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2820
 Met Glu Thr Glu Thr Lys Glu Ser Gly Lys Asn Lys Lys Ile Pro Pro
   1               5                  10                  15    
 Lys His Gln Ile Glu Asn Val Gly Val Gly Gly Leu Gly Ala Gln Asp
              20                  25                  30        
 Gly Leu Asn Gln Ile Gly Lys Ile Pro Pro Val Leu Ser Cys Ser Gln
          35                  40                  45            
 Ser Arg Phe Gly Thr Met Pro Ala Ala Phe Pro Cys Val Phe Pro Pro
      50                  55                  60                
 Gln Ser Leu Gln Val Ser Pro Gln Met Ser Ser Lys Ala Trp Glu Lys
  65                  70                  75                  80
 Gln Ser Leu Pro Leu Pro Gly Leu Arg Gly Ser Pro Val Glu Arg Lys
                  85                  90                  95    
 Asn Arg Asn Tyr Asp Leu Cys Leu Pro Tyr Cys Leu Arg Asn Ile Phe
             100                 105                 110        
 Asn Cys Arg Gly Lys Pro Val Leu Phe Trp Arg Lys Ala Asn Arg
         115                 120                 125        



      <210> 2821
      <211> 108
      <212> PRT
      <213> Homo sapiens


      <400> 2821
 Pro Ala Ser Leu Pro Pro Cys Ser Leu Ile Ser Asp Cys Cys Ala Ser
   1               5                  10                  15    
 Asn Gln Arg Asp Ser Val Gly Val Gly Pro Ser Glu Pro Gly Val Gly
              20                  25                  30        
 Tyr Ser Leu Val Val Arg Arg Phe Leu Ser Arg Ser Glu Lys Arg Asn
          35                  40                  45            
 Ile Arg Val Gly Val Thr Arg Phe Ser Arg Cys Val Leu Ser Pro Leu
      50                  55                  60                
 Ser Leu Thr Gln Lys Gly Asn Ser Leu Thr Pro Cys Ala Ser Gln Val
  65                  70                  75                  80
 Arg Gln Cys Leu Ala Leu Leu Arg Leu Ala His Gly Ala Cys Thr His
                  85                  90                  95    
 Trp Pro Ala Pro Thr Val Trp His Ser Leu Val Arg
             100                 105            



      <210> 2822
      <211> 54
      <212> PRT
      <213> Homo sapiens


      <400> 2822
 Met Gln Lys Arg His Asn Cys Lys Lys Val His Ala Leu Pro Pro Ala
   1               5                  10                  15    
 Val Leu Gly Phe Gln Arg Ala Ser Gly Cys Arg Phe Ala Asn Lys Arg
              20                  25                  30        
 Ser Arg Ile Thr His Phe Gly Gly Arg Arg Leu Ser Leu Thr Pro Ala
          35                  40                  45            
 Ser Asp Ser Ala Gly Val
      50                



      <210> 2823
      <211> 86
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(86)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2823
 Arg Gly Pro Val Ser Arg Asn Gln Pro Pro Phe Thr Arg Phe Pro Gln
   1               5                  10                  15    
 Thr Arg Lys Thr Thr Glu Thr His Val Arg Gly Gln Ser Leu Pro Arg
              20                  25                  30        
 Pro Gly Thr Gln Ser Leu Gln Thr Lys Ala Ala Gln Val Pro Ser Pro
          35                  40                  45            
 Gln Arg Leu Pro Lys Asn Pro Glu Xaa Ala Val Trp Leu Thr Gln Ala
      50                  55                  60                
 Pro Asn Ala His Pro Asn Xaa Val Ala Arg Glu Thr Pro Asn Cys Gln
  65                  70                  75                  80
 Thr Lys Ser Ser Thr Arg
                  85    



      <210> 2824
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 2824
 Pro Thr Arg Pro Pro Leu Gln Leu Gln Ala Pro Arg Ala His Leu Ser
   1               5                  10                  15    
 Glu Asp Gln Lys Arg Leu Leu Leu Met Lys Gln Lys Gly Val Met Asn
              20                  25                  30        
 Gln Pro Met Ala Tyr Ala Ala Leu Pro Ser His Gly Gln Glu Gln His
          35                  40                  45            
 Pro Val Gly Leu Pro Arg Thr Thr Gly Pro Met Gln Ser Ser Val Pro
      50                  55                  60                
 Pro Gly Ser Gly Gly Met Val Ser Gly Ala Ser Pro Ala Gly Pro Gly
  65                  70                  75                  80
 Phe Leu Gly Ser Gln Pro Gln Ala Ala Ile Met Lys Gln Met Leu Ile
                  85                  90                  95    
 Asp Gln Arg Ala Gln Leu Ile Glu Gln Gln Lys Gln Gln Phe Leu Arg
             100                 105                 110        
 Glu Gln Arg Gln Gln Gln Gln Gln Gln Gln Gln Ile Leu Ala Glu Gln
         115                 120                 125            
 Val Thr Cys Pro Leu Ala
     130                



      <210> 2825
      <211> 99
      <212> PRT
      <213> Homo sapiens


      <400> 2825
 Met Val Pro Leu Cys Gln Val Arg Val Ala Gly Val Arg Ala Gly Leu
   1               5                  10                  15    
 Ala Leu Val Ser Arg Thr Ser Pro Leu Ala Pro Asn Leu Ala Gly Val
              20                  25                  30        
 Leu Gly Ser Gly Ala Pro Pro Pro Pro Pro Pro Gly Pro Ser Cys Leu
          35                  40                  45            
 Arg Ala Leu Leu Arg Leu Pro Gln Gln Lys Ser Gly Pro Leu Arg Glu
      50                  55                  60                
 Leu Leu Ser Ala His Gly Ser Lys Asp Gly Leu Val Val Lys Ala Pro
  65                  70                  75                  80
 Thr His Phe Tyr Asp His Leu Phe Pro Arg Leu Phe Val Leu Met Lys
                  85                  90                  95    
 Leu Lys Phe
            



      <210> 2826
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 2826
 Met Lys Ala Leu Leu Ala Leu Pro Leu Leu Leu Leu Leu Ser Thr Pro
   1               5                  10                  15    
 Pro Cys Ala Pro Gln Val Ser Gly Ile Arg Gly Asp Ala Leu Glu Arg
              20                  25                  30        
 Phe Cys Leu Gln Gln Pro Leu Asp Cys Asp Asp Ile Tyr Ala Gln Gly
          35                  40                  45            
 Tyr Gln Ser Asp Gly Val Tyr Leu Ile Tyr Pro Ser Gly Pro Ser Val
      50                  55                  60                
 Pro Val Pro Val Phe Cys Asp Met Thr Thr Glu Gly Gly Lys Trp Thr
  65                  70                  75                  80
 Val Phe Gln Lys Arg Phe Asn Gly Ser Val Ser Phe Phe Arg Gly Trp
                  85                  90                  95    
 Asn Asp Tyr Lys Leu Gly Phe Gly Arg Ala Asp Gly Glu Tyr Trp Leu
             100                 105                 110        
 Gly Leu Gln Asn Met His Leu Leu Thr Leu Lys Gln Lys Tyr Glu Leu
         115                 120                 125            
 Arg Val Asp Leu Glu Asp Phe Glu Asn
     130                 135        



      <210> 2827
      <211> 236
      <212> PRT
      <213> Homo sapiens


      <400> 2827
 Lys Ile Ala Asp Phe Gly Phe Ser Asn Leu Phe Thr Pro Gly Gln Leu
   1               5                  10                  15    
 Leu Lys Thr Trp Cys Gly Ser Pro Pro Tyr Ala Ala Pro Glu Leu Phe
              20                  25                  30        
 Glu Gly Lys Glu Tyr Asp Gly Pro Lys Val Asp Ile Trp Ser Leu Gly
          35                  40                  45            
 Val Val Leu Tyr Val Leu Val Cys Gly Ala Leu Pro Phe Asp Gly Ser
      50                  55                  60                
 Thr Leu Gln Asn Leu Arg Ala Arg Val Leu Ser Gly Lys Phe Arg Ile
  65                  70                  75                  80
 Pro Phe Phe Met Ser Thr Glu Cys Glu His Leu Ile Arg His Met Leu
                  85                  90                  95    
 Val Leu Asp Pro Asn Lys Arg Leu Ser Met Glu Gln Ile Cys Lys His
             100                 105                 110        
 Lys Trp Met Lys Leu Gly Asp Ala Asp Pro Asn Phe Asp Arg Leu Ile
         115                 120                 125            
 Ala Glu Cys Gln Gln Leu Lys Glu Glu Arg Gln Val Asp Pro Leu Asn
     130                 135                 140                
 Glu Asp Val Leu Leu Ala Met Glu Asp Met Gly Leu Asp Lys Glu Gln
 145                 150                 155                 160
 Thr Leu Gln Ser Leu Arg Ser Asp Ala Tyr Asp His Tyr Ser Ala Ile
                 165                 170                 175    
 Tyr Ser Leu Leu Cys Asp Arg His Lys Arg His Lys Thr Leu Arg Leu
             180                 185                 190        
 Gly Ala Leu Pro Ser Met Pro Arg Ala Leu Gly Leu Ser Ser Thr Ser
         195                 200                 205            
 Gln Tyr Pro Ala Glu Gln Ala Gly Thr Ala Met Asn Ile Ser Val Pro
     210                 215                 220                
 Gln Val Gln Leu Ile Asn Pro Glu Asn Gln Ile Val
 225                 230                 235    



      <210> 2828
      <211> 253
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(253)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2828
 Thr Trp Arg Leu Asp Pro Gln Ile Ile Ser Ser Pro Lys Pro Gln Pro
   1               5                  10                  15    
 Gly Gly Thr Tyr Thr Leu Glu Val Val Lys Ser Ser Lys Ser Lys Lys
              20                  25                  30        
 Val Leu Ser Pro His Pro Xaa Trp Pro Pro Leu Arg Leu Trp Gln Arg
          35                  40                  45            
 Gly Gly Ser Pro Glu Gly Gly Thr Gln Ala Pro Asp Gly Ser Leu Pro
      50                  55                  60                
 Pro Pro Pro Pro Arg Pro Lys Ser Glu Arg Val Gly Ser Pro Lys Leu
  65                  70                  75                  80
 Ser Gly Gly Lys Arg Glu Gly Ser His Pro Gly Gly Pro Pro His Ile
                  85                  90                  95    
 Thr His Pro Asp Gly Glu Glu Lys Ala Lys Ser Ser Trp Phe Gly Leu
             100                 105                 110        
 Arg Glu Ala Lys Asp Pro Thr Gln Lys Pro Ser Pro His Pro Val Lys
         115                 120                 125            
 Pro Leu Ser Ala Ala Pro Val Glu Gly Ser Pro Asp Arg Lys Gln Ser
     130                 135                 140                
 Arg Ser Ser Leu Ser Ile Ala Leu Ser Ser Gly Leu Glu Lys Leu Lys
 145                 150                 155                 160
 Thr Val Thr Ser Gly Ser Ile Gln Pro Val Thr Gln Ala Pro Gln Ala
                 165                 170                 175    
 Gly Gln Met Val Asp Thr Lys Arg Leu Lys Asp Ser Ala Val Leu Asp
             180                 185                 190        
 Gln Ser Ala Lys Tyr Tyr His Leu Thr His Asp Glu Leu Ile Ser Leu
         195                 200                 205            
 Leu Leu Gln Arg Glu Arg Glu Leu Ser Gln Arg Asp Glu His Val Gln
     210                 215                 220                
 Glu Leu Glu Ser Tyr Ile Asp Arg Leu Leu Val Arg Ile Met Glu Thr
 225                 230                 235                 240
 Ser Pro Thr Leu Leu Gln Ile Pro Pro Gly Pro Pro Lys
                 245                 250            



      <210> 2829
      <211> 86
      <212> PRT
      <213> Homo sapiens


      <400> 2829
 Trp Gln Gly Gly Ile Leu Gly Ser Asp Pro Thr Pro Pro Leu Thr Ser
   1               5                  10                  15    
 Pro Asn Leu Leu Gln Thr Ala Cys Phe Arg Glu Glu Arg Asp Val Arg
              20                  25                  30        
 Arg Glu Arg Gly Gln Pro Leu Gly Asp His Ser Ala Leu Cys Leu Pro
          35                  40                  45            
 Arg Arg Gly Val Pro Val Pro Cys Asp Gly Leu Leu Cys Trp Trp Gly
      50                  55                  60                
 Pro Pro Asp Ala Ala Glu Pro Leu Arg Gly Pro Ser Pro Ala Arg Ala
  65                  70                  75                  80
 Gly Pro Val Leu Pro Gly
                  85    



      <210> 2830
      <211> 354
      <212> PRT
      <213> Homo sapiens


      <400> 2830
 Met Thr Ala Asp Ala Val Leu Ile Lys Asn Gly Ser Lys Asp Ala Asp
   1               5                  10                  15    
 Trp Glu Tyr Glu Glu Gly Asp Lys Leu Glu Glu Phe Leu Arg Ser Leu
              20                  25                  30        
 Asn Ser Ser Lys Pro Leu Tyr Leu Gly Gln Thr Gly Leu Gly Asn Ile
          35                  40                  45            
 Glu Glu Leu Gly Lys Leu Gly Leu Glu Pro Gly Glu Asn Phe Cys Met
      50                  55                  60                
 Gly Gly Pro Gly Met Ile Phe Ser Arg Glu Val Leu Arg Arg Met Val
  65                  70                  75                  80
 Pro His Ile Gly Glu Cys Leu Arg Glu Met Tyr Thr Thr His Glu Asp
                  85                  90                  95    
 Val Glu Val Gly Arg Cys Val Arg Arg Phe Gly Gly Thr Gln Cys Val
             100                 105                 110        
 Trp Ser Tyr Glu Gly Arg Cys Ser Phe Arg Val Val Pro Asp Ser Ala
         115                 120                 125            
 Ile Glu Phe Ser Met Asp Phe Glu Lys Ile Leu Met Leu Asp Pro Thr
     130                 135                 140                
 Leu His Pro Leu Cys Gln Asn Leu Leu Gln Arg Leu Asn Thr Met Trp
 145                 150                 155                 160
 Lys Pro Pro Asn Val Gly Leu Val Pro Ser Lys Ala Thr Ala Gln Ala
                 165                 170                 175    
 Val Arg Trp Ser Leu Leu Ala Met Ala Arg Ala Gly Ala Ala Thr Met
             180                 185                 190        
 Pro Gly Ala Leu Ser Gln Gly Cys Ile Glu Val Ser Arg Leu Leu Lys
         195                 200                 205            
 Lys Leu Pro Asp Asp Glu Gly Ile Thr Met Asp Thr Val Gly Phe Ala
     210                 215                 220                
 Pro Leu Cys Leu Trp Gln Arg Leu Thr Leu Ala Asn His Gln Arg Tyr
 225                 230                 235                 240
 Phe Ala Asp Gly Pro Gln Pro Val Cys Asn His Met Gln Pro Ala Pro
                 245                 250                 255    
 His His Phe Ala Ser Met Arg Ser Ser Ala Ala Ser Pro Thr Ser Leu
             260                 265                 270        
 Pro Ala Phe Ala Asp Pro Ala Ala Val Pro Pro Leu Glu His Val Tyr
         275                 280                 285            
 Val Trp Thr Leu Leu Leu Cys Gln Arg Trp Cys Thr Tyr Met Tyr Met
     290                 295                 300                
 Asp Ser Thr Ala Thr Thr Leu Thr Lys His Cys Cys Cys Pro Pro Pro
 305                 310                 315                 320
 Ile Pro Pro Ile Gly Val Leu Leu Pro Ala Asp Trp Gly His Ile Gly
                 325                 330                 335    
 Pro Ser Ser Asp Ser Arg Ser Glu Asn Lys Ala Met Gly Ser Ser Pro
             340                 345                 350        
 Ser Thr
        



      <210> 2831
      <211> 78
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(78)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2831
 Thr Lys Leu Asn Pro Lys Ile Met Asp Val Gly Trp Pro Glu Leu His
   1               5                  10                  15    
 Ala Pro Pro Leu Asp Lys Met Cys Thr Ile Cys Lys Ala Gln Glu Ser
              20                  25                  30        
 Trp Leu Asn Ser Asn Leu Gln His Val Val Val Ile His Cys Arg Gly
          35                  40                  45            
 Gly Lys Gly Arg Ile Gly Val Val Ile Ser Ser Tyr Met His Phe Thr
      50                  55                  60                
 Asn Val Ser Ala Arg Xaa Asp Glu Asp Val Ser Ser Leu Ser
  65                  70                  75            



      <210> 2832
      <211> 52
      <212> PRT
      <213> Homo sapiens


      <400> 2832
 Arg Leu His Thr Ala Asn Leu Gly Asp Ser Gly Phe Leu Val Val Arg
   1               5                  10                  15    
 Gly Gly Glu Val Val His Arg Ser Asp Glu Gln Gln His Tyr Phe Asn
              20                  25                  30        
 Thr Pro Phe Gln Leu Ser Ile Ala Pro Pro Glu Ala Glu Gly Val Val
          35                  40                  45            
 Leu Ser Asp Arg
      50        



      <210> 2833
      <211> 329
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(329)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2833
 Met Pro Ala Glu Phe Phe Gln Arg Cys Ser Val Ile Met Val Gln Leu
   1               5                  10                  15    
 Pro Trp Lys Glu Ala His Val Glu Arg Pro His Gly Glu Arg Asp Tyr
              20                  25                  30        
 Thr Pro Asp Leu Gln Pro Asp Met Trp Glu Lys Phe Pro Gly Leu Arg
          35                  40                  45            
 Arg Ala Leu Arg Pro Val Val Lys Thr Leu Leu Val Gln Leu Glu Tyr
      50                  55                  60                
 Arg Gln Ala Glu Lys Cys Glu Lys Arg Asp Trp Pro Ser Leu Pro Asp
  65                  70                  75                  80
 Tyr Ile Phe Leu Leu Cys Trp Met Leu Pro Ala Leu Glu Tyr Arg Thr
                  85                  90                  95    
 Pro Ser Ser Ser Val Leu Glu Leu Arg Leu Ala Leu Arg Ala Pro Gln
             100                 105                 110        
 Pro Ala Asp Ser Leu Leu Trp Asp Leu Val Ile Val Pro Ile Thr Ser
         115                 120                 125            
 Leu Lys Ser Trp Gln Thr Pro Arg Gly Glu Val Glu Gly Val Thr His
     130                 135                 140                
 Glu Glu Ile Cys Ala Ser Leu Lys Ser Leu Ala Val Ala Leu Leu Ser
 145                 150                 155                 160
 Met Ser Asp Leu Thr Val Gly Thr Pro Val Thr Gln Pro Gln Thr Leu
                 165                 170                 175    
 Asn Thr Met Gly Ile Ile Gly Ser Arg Gly Gly Arg Gly Gln Val Ala
             180                 185                 190        
 Ala Leu Asn Arg Gln Arg Gln Val Pro Glu Leu Ile Ile Gly Ile Asp
         195                 200                 205            
 Ile Leu Ser Ser Trp Gln Asn Pro His Ile Gly Ser Leu Asn Gly Arg
     210                 215                 220                
 Gly Tyr Ile Asn Ser Leu Ala Leu Cys His Asn Leu Ile Arg Arg Asp
 225                 230                 235                 240
 Leu Asp Arg Phe Leu Leu Pro Gln Asp Ile Thr Leu Val His Tyr Ile
                 245                 250                 255    
 Asp His Ile Met Arg Leu Asp Ser Val Lys Asp Lys Trp Leu His Leu
             260                 265                 270        
 Ala Pro Pro Thr Thr Lys Lys Glu Ala Gln Cys Leu Val Gly Leu Phe
         275                 280                 285            
 Gly Phe Trp Arg Gln His Ile Ser His Leu Glu Thr Ala Leu Arg Pro
     290                 295                 300                
 Val Thr Gly Leu Trp Trp Lys Leu Asn Ile Xaa Leu Trp Ala Ile Lys
 305                 310                 315                 320
 Ser Pro Cys Asn Leu Asn Cys Leu Ser
                 325                



      <210> 2834
      <211> 411
      <212> PRT
      <213> Homo sapiens


      <400> 2834
 Glu Ala Gly Pro Ala Pro Leu Ser Ala Ala Ala Pro Gly Ala Gly Arg
   1               5                  10                  15    
 Gly Trp Pro Arg Pro Leu Ala Glu Arg Arg Lys Gly Arg Gly Arg Arg
              20                  25                  30        
 Gln Pro Leu Arg Ala Arg Leu Asn Arg Arg Arg Trp Ala Ala Gly Gln
          35                  40                  45            
 Gly Ser Thr Val Gln Ala Ala Thr Phe Gly Pro Ala Met Ala Ala Ala
      50                  55                  60                
 Pro Leu Lys Val Cys Ile Val Gly Ser Gly Asn Trp Gly Ser Ala Val
  65                  70                  75                  80
 Ala Lys Ile Ile Gly Asn Asn Val Lys Lys Leu Gln Lys Phe Ala Ser
                  85                  90                  95    
 Thr Val Lys Met Trp Val Phe Glu Glu Thr Val Asn Gly Arg Lys Leu
             100                 105                 110        
 Thr Asp Ile Ile Asn Asn Asp His Glu Asn Val Lys Tyr Leu Pro Gly
         115                 120                 125            
 His Lys Leu Pro Glu Asn Val Val Ala Met Ser Asn Leu Ser Glu Ala
     130                 135                 140                
 Val Gln Asp Ala Asp Leu Leu Val Phe Val Ile Pro His Gln Phe Ile
 145                 150                 155                 160
 His Arg Ile Cys Asp Glu Ile Thr Gly Arg Val Pro Lys Lys Ala Leu
                 165                 170                 175    
 Gly Ile Thr Leu Ile Lys Gly Ile Asp Glu Gly Pro Glu Gly Leu Lys
             180                 185                 190        
 Leu Ile Ser Asp Ile Ile Arg Glu Lys Met Gly Ile Asp Ile Ser Val
         195                 200                 205            
 Leu Met Gly Ala Asn Ile Ala Asn Glu Val Ala Ala Glu Lys Phe Cys
     210                 215                 220                
 Glu Thr Thr Ile Gly Ser Lys Val Met Glu Asn Gly Leu Leu Phe Lys
 225                 230                 235                 240
 Glu Leu Leu Gln Thr Pro Asn Phe Arg Ile Thr Val Val Asp Asp Ala
                 245                 250                 255    
 Asp Thr Val Glu Leu Cys Gly Ala Leu Lys Asn Ile Val Ala Val Gly
             260                 265                 270        
 Ala Gly Phe Cys Asp Gly Leu Arg Cys Gly Asp Asn Thr Lys Ala Ala
         275                 280                 285            
 Val Ile Arg Leu Gly Leu Met Glu Met Ile Ala Phe Ala Arg Ile Phe
     290                 295                 300                
 Cys Lys Gly Gln Val Ser Thr Ala Thr Phe Leu Glu Ser Cys Gly Val
 305                 310                 315                 320
 Ala Asp Leu Ile Thr Thr Cys Tyr Gly Gly Arg Asn Arg Arg Val Ala
                 325                 330                 335    
 Glu Ala Phe Ala Arg Thr Gly Lys Thr Ile Glu Glu Leu Glu Lys Glu
             340                 345                 350        
 Met Leu Asn Gly Gln Lys Leu Gln Gly Pro Gln Thr Ser Ala Glu Val
         355                 360                 365            
 Tyr Arg Ile Leu Lys Gln Lys Gly Leu Leu Asp Lys Phe Pro Leu Phe
     370                 375                 380                
 Thr Ala Val Tyr Gln Ile Cys Tyr Glu Ser Arg Pro Val Gln Glu Met
 385                 390                 395                 400
 Leu Ser Cys Leu Gln Ser His Pro Glu His Thr
                 405                 410    



      <210> 2835
      <211> 569
      <212> PRT
      <213> Homo sapiens


      <400> 2835
 Gln Leu Leu Pro Thr Asp Thr Pro Thr Gly Asn Ser Ser Pro Ser Leu
   1               5                  10                  15    
 Pro His Leu Pro Phe Ala Gly Ala Cys Gly Leu Ser Ile Tyr Asn Leu
              20                  25                  30        
 Val Pro Thr Gln Gln Lys Arg Asn Pro Ser Gly Ser Ser Gly Phe Ile
          35                  40                  45            
 Leu Ser Arg Ile Cys Phe Thr Asn Tyr Ser Pro Val Pro Pro Ser Leu
      50                  55                  60                
 Gln Met Phe Phe Arg Leu Gln Leu Pro Pro Val Asn Ser Glu Glu Thr
  65                  70                  75                  80
 Ser His Tyr Glu Ile Pro Leu Pro Gly Arg Arg Val Glu Leu Arg Tyr
                  85                  90                  95    
 Pro Leu Arg Gln Gly Thr Glu Ala Thr Asp Gly Gln Val Cys Gly Asn
             100                 105                 110        
 Glu Asp Met Leu Ile Arg Asp Arg Val Arg Lys Thr Arg Gly Ser Ala
         115                 120                 125            
 Pro Pro Pro Ala His Asn Leu Ala Pro Thr Glu Val Ala Leu Glu Asp
     130                 135                 140                
 Val Leu Arg Ile Phe Thr Ser Ala Trp Arg Gly Val Asp Gly Ala Leu
 145                 150                 155                 160
 Glu Lys Gly Gly Thr Ser Cys Pro Ala Arg Ala Gln Leu Pro Ala Glu
                 165                 170                 175    
 Pro Glu Asp Pro Leu Phe Arg Cys Leu Arg Val Ser Arg Leu Lys Asp
             180                 185                 190        
 Arg Glu Val Arg Gly Leu Gly Leu Pro Arg Gln Leu Gln Gly Val Trp
         195                 200                 205            
 Ser Thr Thr Tyr Pro Arg Arg His Ala Ile Ala Glu His Ala Gly Ser
     210                 215                 220                
 Pro Lys Pro Leu Arg Lys Arg Glu Pro Glu Thr Trp Gln Ala Asn Lys
 225                 230                 235                 240
 Lys Gly Val Ile Gly Ile Gln Leu Val Val Thr Met Val Met Ala Ser
                 245                 250                 255    
 Val Met Gln Lys Ile Ile Pro His Tyr Ser Leu Ala Arg Trp Leu Leu
             260                 265                 270        
 Cys Asn Gly Arg Lys Tyr Asn Gly His Ile Glu Ser Lys Pro Leu Thr
         275                 280                 285            
 Ile Pro Lys Asp Ile Asp Leu His Leu Glu Thr Lys Ser Val Thr Glu
     290                 295                 300                
 Val Asp Thr Leu Ala Leu His Tyr Phe Pro Glu Tyr Gln Trp Leu Val
 305                 310                 315                 320
 Asp Phe Thr Val Ala Ala Thr Val Val Tyr Leu Val Thr Glu Val Tyr
                 325                 330                 335    
 Tyr Asn Phe Met Lys Pro Thr Gln Glu Met Asn Ile Ser Leu Val Cys
             340                 345                 350        
 Lys Val Leu Phe Ser Leu Thr Thr His Tyr Phe Lys Val Glu Asp Gly
         355                 360                 365            
 Gly Glu Arg Ser Val Cys Val Thr Phe Gly Phe Phe Phe Phe Val Lys
     370                 375                 380                
 Ala Met Ala Val Leu Ile Val Thr Glu Asn Tyr Leu Glu Phe Gly Leu
 385                 390                 395                 400
 Glu Thr Gly Phe Thr Asn Phe Ser Asp Ser Ala Met Gln Phe Leu Glu
                 405                 410                 415    
 Lys Gln Gly Leu Glu Ser Gln Thr Leu Leu His Ile Asn Phe Leu Ala
             420                 425                 430        
 Pro Leu Phe Met Val Leu Leu Trp Val Lys Pro Ile Thr Lys Asp Tyr
         435                 440                 445            
 Ile Met Asn Pro Pro Leu Gly Lys Glu Ser Ile Pro Leu Met Thr Glu
     450                 455                 460                
 Ala Thr Phe Asp Thr Leu Arg Leu Trp Leu Ile Ile Leu Leu Cys Ala
 465                 470                 475                 480
 Leu Arg Leu Ala Met Met Arg Ser His Leu Gln Ala Tyr Leu Asn Leu
                 485                 490                 495    
 Ala Gln Lys Cys Val Asp Gln Met Lys Lys Glu Ala Gly Arg Ile Ser
             500                 505                 510        
 Thr Val Glu Leu Gln Lys Met Val Ala Arg Val Phe Tyr Tyr Leu Cys
         515                 520                 525            
 Val Ile Ala Leu Gln Tyr Val Ala Pro Leu Val Met Leu Leu His Thr
     530                 535                 540                
 Thr Leu Leu Leu Lys Thr Leu Gly Asn His Ser Trp Gly Tyr Leu Ser
 545                 550                 555                 560
 Arg Ile Tyr Leu Tyr Leu Thr Ser Gly
                 565                



      <210> 2836
      <211> 257
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(257)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2836
 His Ser Tyr Ser His Ser His Gly His Cys Gly Ser Pro Ala Gly Asp
   1               5                  10                  15    
 Thr Glu Gln Gly Tyr Lys Pro Val Trp Pro Val Cys Ser Leu Phe Pro
              20                  25                  30        
 Asp Gly Ser His Pro Gly Val Xaa Gln Pro Ile His Glu Pro Ala Gln
          35                  40                  45            
 Gly Arg Gly Gly Leu Pro Pro Trp Gly Ala Ala Xaa Thr Pro Arg Ala
      50                  55                  60                
 Trp Arg Leu Ala Xaa Arg Pro Arg Gly Xaa Ala Ala Leu Pro Trp Ala
  65                  70                  75                  80
 Xaa Thr Ser Pro Gly Arg Pro Ala Ser Ala Pro Leu Ala His Thr Gly
                  85                  90                  95    
 Ser Gly Cys Pro Ser Arg Pro Thr Arg Ala Pro Gly Pro Ser Pro Ile
             100                 105                 110        
 Pro Ile Gln Asn Ile Lys Arg Pro Tyr Pro Gly Glu Ala Phe Val Pro
         115                 120                 125            
 Ser Arg Ala Gly Pro Thr Val Gly Val Thr Arg Ser Phe His Leu Ala
     130                 135                 140                
 Pro Ser Leu Pro Pro Phe Pro Ser Ser Xaa Leu Ser Pro Ser Leu Pro
 145                 150                 155                 160
 Pro Arg Thr Thr Thr Ser Cys Thr Arg Ala Ile Leu Thr Pro Ser Ser
                 165                 170                 175    
 Xaa Gln Lys Leu Leu Tyr Pro Pro Ser Arg Pro Val Val Leu Leu Val
             180                 185                 190        
 Arg Arg Ala Arg Pro Pro Ala Ala Ala Pro Thr Ser Glu Glu Pro Pro
         195                 200                 205            
 Glu Arg Ser Pro Trp Glu Thr Pro His Ala Ala Pro Ser Gln Leu His
     210                 215                 220                
 Glu Leu His Glu Thr His Ser Val Ala Gln Lys Ser Asp Leu Leu Pro
 225                 230                 235                 240
 Ala Pro Glu Ala Met Xaa Pro Gly Ser Val Ser Ser Arg Phe Leu Leu
                 245                 250                 255    
 Tyr
    



      <210> 2837
      <211> 173
      <212> PRT
      <213> Homo sapiens


      <400> 2837
 Cys Ser Ala Ala Trp Ala Pro Lys Leu Gln Leu Leu Ser Val Cys Arg
   1               5                  10                  15    
 Gln Gln Leu Pro Gly Asn Pro Arg Ala Arg Ser His Ser His His Arg
              20                  25                  30        
 Arg Thr Arg Ala Arg Cys Pro Ser Gly Cys Gly Gln Ala Arg His Ser
          35                  40                  45            
 Ala Gly Ser Trp His Lys Leu Gln Phe Pro Leu Cys Pro Trp Lys Met
      50                  55                  60                
 Arg Ser Pro Leu Lys Met Arg Ser Leu Leu Lys Met Ile Pro Ser Glu
  65                  70                  75                  80
 Ser Arg Met Val Val Thr Phe Leu Ile Ser Ala Leu Glu Ser Thr Glu
                  85                  90                  95    
 Gln Tyr His Gly Gly Val Tyr Thr Pro Cys Asp Ile Asp Ser Asn Ile
             100                 105                 110        
 Ile Leu Ser Pro Pro Asp Ile Ser Asn Asn Ile Thr Glu Gly Val Tyr
         115                 120                 125            
 Thr Pro Cys Asp Ile Asp Arg His Leu Ile Pro Phe Phe Leu Pro Leu
     130                 135                 140                
 Asp Met Arg Leu Gln Val Leu Met Pro Leu Asp Ser Gly Thr Cys Thr
 145                 150                 155                 160
 Ser Gly Phe Pro Glu Ala Leu Arg Pro Ser Ala Ser Asp
                 165                 170            



      <210> 2838
      <211> 414
      <212> PRT
      <213> Homo sapiens


      <400> 2838
 Trp Pro Cys Gly Ala Ala Pro Gly Leu Thr His Ala Ser Glu Arg Met
   1               5                  10                  15    
 Phe Thr Leu Thr Thr Met Ile Gln Ala Leu Ala Pro Val Met Gly Trp
              20                  25                  30        
 Asp Arg Lys Pro Leu Lys Met Phe Ser Ser Glu Glu Met Arg Gly His
          35                  40                  45            
 Leu His His His His Lys Cys Leu Thr Lys Ile Leu Lys Val Glu Gly
      50                  55                  60                
 Gln Val Pro Asp Leu Pro Ser Cys Leu Pro Leu Thr Asp Asn Thr Arg
  65                  70                  75                  80
 Met Leu Ala Ser Ile Leu Ile Asn Met Leu Tyr Asp Asp Leu Arg Cys
                  85                  90                  95    
 Asp Pro Glu Arg Asp His Phe Arg Lys Ile Cys Glu Glu Tyr Ile Thr
             100                 105                 110        
 Gly Lys Phe Asp Pro Gln Asp Met Asp Lys Asn Leu Asn Ala Ile Gln
         115                 120                 125            
 Thr Val Ser Gly Ile Leu Gln Gly Pro Phe Asp Leu Gly Asn Gln Leu
     130                 135                 140                
 Leu Gly Leu Lys Gly Val Met Glu Met Met Val Ala Leu Cys Gly Ser
 145                 150                 155                 160
 Glu Arg Glu Thr Asp Gln Leu Val Ala Val Glu Ala Leu Ile His Ala
                 165                 170                 175    
 Ser Thr Lys Leu Ser Arg Ala Thr Phe Ile Ile Thr Asn Gly Val Ser
             180                 185                 190        
 Leu Leu Lys Gln Ile Tyr Lys Thr Thr Lys Asn Glu Lys Ile Lys Ile
         195                 200                 205            
 Arg Thr Leu Val Gly Leu Cys Lys Leu Gly Ser Ala Gly Gly Thr Asp
     210                 215                 220                
 Tyr Gly Leu Arg Gln Phe Ala Glu Gly Ser Thr Glu Lys Leu Ala Lys
 225                 230                 235                 240
 Gln Cys Arg Lys Trp Leu Cys Asn Met Ser Ile Asp Thr Arg Thr Arg
                 245                 250                 255    
 Arg Trp Ala Val Glu Gly Leu Ala Tyr Leu Thr Leu Asp Ala Asp Val
             260                 265                 270        
 Lys Asp Asp Phe Val Gln Asp Val Pro Ala Leu Gln Ala Met Phe Glu
         275                 280                 285            
 Leu Ala Lys Thr Ser Asp Lys Thr Ile Leu Tyr Ser Val Ala Thr Thr
     290                 295                 300                
 Leu Val Asn Cys Thr Asn Ser Tyr Asp Val Lys Glu Val Ile Pro Glu
 305                 310                 315                 320
 Leu Val Gln Leu Ala Lys Phe Ser Lys Gln His Val Pro Glu Glu His
                 325                 330                 335    
 Pro Lys Asp Lys Lys Asp Phe Ile Asp Met Arg Val Lys Arg Leu Leu
             340                 345                 350        
 Lys Ala Gly Val Ile Ser Ala Leu Ala Cys Met Val Lys Ala Asp Ser
         355                 360                 365            
 Ala Ile Leu Thr Asp Gln Thr Lys Glu Leu Leu Ala Arg Val Phe Leu
     370                 375                 380                
 Ala Leu Cys Asp Asn Pro Lys Asp Arg Gly Thr Ile Val Ala Gln Gly
 385                 390                 395                 400
 Gly Gly Lys Ala Leu Ile Pro Leu Ala Leu Glu Gly Thr Asp
                 405                 410                



      <210> 2839
      <211> 109
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(109)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2839
 Glu Asp Ser Gly Leu Arg Leu Leu Trp Ile Cys Leu Ser Leu Ser Leu
   1               5                  10                  15    
 Ser Phe Pro Xaa Asn Arg Val Ser Leu Cys His Pro Gly Trp Ser Ala
              20                  25                  30        
 Val Ala Arg Pro Gln Leu Thr Ala Ala Arg Pro Ser Arg Leu Gln Gln
          35                  40                  45            
 Ser Ser His Leu Ser Leu Gln Ser Thr Trp Asp His Arg His Thr Pro
      50                  55                  60                
 Pro Tyr Leu Ala Leu Phe Phe Ile Phe Leu Phe Leu Val Asp Met Ser
  65                  70                  75                  80
 Phe Thr Thr Val Pro Arg Pro Val Leu Asn Ser Trp Ala Gln Ala Ile
                  85                  90                  95    
 Leu Pro Phe Arg Pro Leu Lys Val Leu Gly Leu Leu Ala
             100                 105                



      <210> 2840
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 2840
 Met Tyr Met Leu Leu Gln Ala Phe Trp Leu Trp Gln Glu Thr Leu Lys
   1               5                  10                  15    
 Thr Ile Leu Leu Tyr Lys Phe Thr Lys Pro Pro Ala Asn Thr Pro Val
              20                  25                  30        
 Leu Gly Val Asn Ala Gln Val Cys His Ser Cys Leu Ala Ala Leu Arg
          35                  40                  45            
 Ile Arg Lys Val Asn Gly His Lys Arg Asn Phe Lys Ala Gln Pro Pro
      50                  55                  60                
 Asn Gly Lys Leu Pro Leu Val Leu Gly Cys Leu Cys Leu Leu Thr Asp
  65                  70                  75                  80
 Leu Ile His Ala Leu Gly Tyr Asp Cys Arg Arg Asp Phe Pro Val Ser
                  85                  90                  95    
 Leu Glu Tyr Ala Glu Leu Val Phe Leu Phe Val Val Ala Tyr
             100                 105                 110



      <210> 2841
      <211> 57
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(57)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2841
 Leu Asp Phe Phe Leu Val Phe Leu Gln Gln Phe Leu Pro Arg Pro Ser
   1               5                  10                  15    
 Ser Ser Glu Ile Xaa Met Leu Pro Gly Phe Pro Ala Ala Ala Tyr Gly
              20                  25                  30        
 Pro Val Ala Ala Ala Ala Val Ala Ala Ala Arg Gly Ser Gly Arg Lys
          35                  40                  45            
 Val Tyr Gly Thr Gly Asp Ser Gln Ala
      50                  55        



      <210> 2842
      <211> 117
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(117)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2842
 Lys Thr Trp Thr Pro Gln Pro Arg His Pro Pro Pro His Pro Glu Thr
   1               5                  10                  15    
 Ser Lys Pro Thr Pro Pro Cys Xaa Gly Pro Val Leu Cys Ser Cys Leu
              20                  25                  30        
 Lys Val Met Pro Arg Pro Leu Pro Pro Pro Pro Xaa Asp Leu Cys Ser
          35                  40                  45            
 Pro Pro Leu Leu Ala Pro Gly Pro Arg Arg Ser Ala Gly Gly Cys Trp
      50                  55                  60                
 Ala Cys Gln Arg Arg Lys Lys Met Ser Cys Leu Gly Gly Ala Gly Val
  65                  70                  75                  80
 Cys Leu Lys Gln Gly His Gly His Met Gly Leu Cys Tyr Asp Leu Gly
                  85                  90                  95    
 Leu Ser Thr Leu Ala Glu Pro Pro Gly Ser Ser Ala Arg Arg Leu Pro
             100                 105                 110        
 Ala Arg Ser Ala Leu
         115        



      <210> 2843
      <211> 135
      <212> PRT
      <213> Homo sapiens


      <400> 2843
 Met Ala Glu Thr Ala Val Ile Asn His Lys Lys Arg Lys Asn Ser Pro
   1               5                  10                  15    
 Arg Ile Val Gln Ser Asn Asp Leu Thr Glu Ala Ala Tyr Ser Leu Ser
              20                  25                  30        
 Arg Asp Gln Lys Arg Met Leu Tyr Leu Phe Val Asp Gln Ile Arg Lys
          35                  40                  45            
 Ser Asp Gly Thr Leu Gln Glu His Asp Gly Ile Cys Glu Ile His Val
      50                  55                  60                
 Ala Lys Tyr Ala Glu Ile Phe Gly Leu Thr Ser Ala Glu Ala Ser Lys
  65                  70                  75                  80
 Asp Ile Arg Gln Ala Leu Lys Ser Phe Ala Gly Lys Glu Val Val Phe
                  85                  90                  95    
 Tyr Arg Pro Glu Lys Asp Ala Gly Asp Glu Lys Gly Tyr Glu Ser Phe
             100                 105                 110        
 Pro Trp Phe Ile Lys His Ser Thr Asn Ile Thr Ser Leu Ser Leu Trp
         115                 120                 125            
 Phe Phe Ser Ser Cys Thr His
     130                 135



      <210> 2844
      <211> 298
      <212> PRT
      <213> Homo sapiens


      <400> 2844
 Met Pro Gly Pro Met Ser Leu Trp Leu Leu Leu Leu Val Leu Pro Leu
   1               5                  10                  15    
 Ser Leu Glu His Ser Asp Leu Arg Ile Cys Phe Pro Gly Gln Val Val
              20                  25                  30        
 Ser Met Glu Ser Ser Ser Thr Gly Phe Ile Trp Thr Asp Val Arg Ala
          35                  40                  45            
 Trp Gln Thr Ser Asn Arg His Val Ser Ser Trp Arg Glu Pro Arg His
      50                  55                  60                
 Ser Arg Met Pro Pro Gly Ala Gly Leu Met Glu Arg Ile Gln Ala Ile
  65                  70                  75                  80
 Ala Gln Asn Val Ser Asp Ile Ala Val Lys Val Asp Gln Ile Leu Arg
                  85                  90                  95    
 His Ser Leu Leu Leu His Ser Lys Val Ser Glu Gly Arg Arg Asp Gln
             100                 105                 110        
 Cys Glu Ala Pro Ser Asp Pro Lys Phe Pro Asp Cys Ser Gly Lys Val
         115                 120                 125            
 Glu Trp Met Arg Ala Arg Trp Thr Ser Asp Pro Cys Tyr Ala Phe Phe
     130                 135                 140                
 Gly Val Asp Gly Thr Glu Cys Ser Phe Leu Ile Tyr Leu Ser Glu Val
 145                 150                 155                 160
 Glu Trp Phe Cys Pro Pro Leu Pro Trp Arg Asn Gln Thr Ala Ala Gln
                 165                 170                 175    
 Arg Ala Pro Lys Pro Leu Pro Lys Val Gln Ala Val Phe Arg Ser Asn
             180                 185                 190        
 Leu Ser His Leu Leu Asp Leu Met Gly Ser Gly Lys Glu Ser Leu Ile
         195                 200                 205            
 Phe Met Lys Lys Arg Thr Lys Arg Leu Thr Ala Gln Trp Ala Leu Ala
     210                 215                 220                
 Ala Gln Arg Leu Ala Gln Lys Leu Gly Ala Thr Gln Arg Asp Gln Lys
 225                 230                 235                 240
 Gln Ile Leu Val His Ile Gly Phe Leu Thr Glu Glu Ser Gly Asp Val
                 245                 250                 255    
 Phe Ser Pro Arg Val Leu Lys Gly Gly Pro Leu Gly Glu Met Val Gln
             260                 265                 270        
 Trp Ala Asp Ile Leu Thr Ala Leu Tyr Val Leu Gly His Gly Leu Arg
         275                 280                 285            
 Val Thr Val Ser Leu Lys Glu Leu Gln Arg
     290                 295            



      <210> 2845
      <211> 613
      <212> PRT
      <213> Homo sapiens


      <400> 2845
 Thr Asn Asp Lys Asn His Met Ile Thr Ser Val Asp Gly Glu Lys Ala
   1               5                  10                  15    
 Phe Asp Lys Ile Gln Gln Pro Phe Met Leu Lys Thr Leu Asn Lys Leu
              20                  25                  30        
 Val Leu Glu Val Leu Ala Arg Ala Ile Arg Gln Glu Lys Gly Ile Lys
          35                  40                  45            
 Gly Ile Gln Leu Gly Lys Glu Glu Val Lys Leu Ser Leu Phe Ala Asp
      50                  55                  60                
 Asp Met Ile Val Tyr Leu Glu Asn Pro Ile Val Ser Ala Gln Asn Leu
  65                  70                  75                  80
 Leu Lys Leu Ile Ser Asn Phe Asn Lys Val Ser Gly Tyr Lys Ile Asn
                  85                  90                  95    
 Val Gln Lys Ser Gln Ala Phe Val Tyr Thr Asn Asn Arg Gln Thr Glu
             100                 105                 110        
 Ser Gln Ile Met Ser Glu Leu Pro Phe Thr Ile Ala Ser Lys Arg Ile
         115                 120                 125            
 Lys Tyr Leu Gly Ile Gln Leu Thr Arg Asp Val Lys Asp Phe Phe Lys
     130                 135                 140                
 Glu Asn Tyr Lys Pro Leu Leu Asn Glu Ile Lys Glu Asp Thr Asn Lys
 145                 150                 155                 160
 Trp Lys Lys Ile Pro Cys Ser Trp Val Gly Arg Ile Asn Ile Val Lys
                 165                 170                 175    
 Met Ala Ile Leu Pro Lys Val Ile Tyr Arg Phe Asn Ala Ile Pro Ile
             180                 185                 190        
 Lys Leu Pro Met Thr Phe Phe Thr Lys Leu Glu Lys Thr Thr Leu Lys
         195                 200                 205            
 Phe Ile Trp Asn Gln Lys Arg Ala His Ile Ala Lys Thr Ile Leu Ser
     210                 215                 220                
 Gln Lys Asn Lys Ala Gly Ser Ile Ala Leu Pro Asp Phe Lys Leu Tyr
 225                 230                 235                 240
 Trp Lys Ala Thr Val Thr Lys Thr Ala Trp Tyr Trp Tyr Gln Asn Arg
                 245                 250                 255    
 Asp Ile Asp Gln Trp Asn Arg Ile Glu Pro Ser Glu Ile Ile Pro His
             260                 265                 270        
 Ile Tyr Asn His Leu Ile Phe Asp Lys Pro Asp Lys Asn Lys Lys Trp
         275                 280                 285            
 Gly Lys Asp Ser Leu Phe Asn Lys Trp Cys Trp Glu Asn Trp Leu Ala
     290                 295                 300                
 Ile Cys Arg Lys Leu Lys Leu Asp Pro Phe Leu Thr Pro Tyr Thr Lys
 305                 310                 315                 320
 Ile Asn Ser Arg Trp Ile Lys Asp Leu Asn Val Arg Pro Lys Thr Ile
                 325                 330                 335    
 Lys Thr Leu Glu Glu Asn Leu Gly Asn Thr Ile Gln Ala Met Gly Met
             340                 345                 350        
 Gly Lys Asp Phe Met Thr Glu Thr Pro Lys Ala Met Ala Thr Lys Ala
         355                 360                 365            
 Lys Ile Asp Lys Trp Asp Leu Ile Lys Leu Lys Ser Phe Cys Thr Ala
     370                 375                 380                
 Lys Glu Thr Thr Ile Arg Val Asn Arg Gln Pro Thr Glu Trp Glu Lys
 385                 390                 395                 400
 Ile Phe Thr Ile Tyr Pro Ser Asp Lys Gly Leu Ile Ser Arg Ile Tyr
                 405                 410                 415    
 Asn Glu Leu Lys Gln Ile Asn Lys Lys Lys Ser Asn Asn Pro Ile Asn
             420                 425                 430        
 Lys Trp Ala Lys Asp Met Asn Arg Arg Phe Ser Lys Glu Asp Ile Tyr
         435                 440                 445            
 Ala Ala Asn Arg His Met Lys Lys Cys Ser Ser Ser Leu Ala Ile Arg
     450                 455                 460                
 Glu Met Gln Ile Lys Thr Thr Met Arg Tyr His Leu Thr Pro Val Arg
 465                 470                 475                 480
 Met Ala Ile Ile Lys Lys Ser Gly Asn Asn Arg Cys Trp Arg Ala Cys
                 485                 490                 495    
 Gly Glu Ile Gly Thr Val Gly Tyr Lys Asn Asp Arg Gln Glu Thr Gln
             500                 505                 510        
 Arg Thr Arg Lys Leu His Asn Ile Leu Glu Asp Lys Pro Tyr Gly Glu
         515                 520                 525            
 Ile Asn Gln Ile Phe Leu Gln Val Gly Gln Arg Lys Asn Gly Tyr Ala
     530                 535                 540                
 Arg Pro Gln Lys Ser Cys Leu Pro Cys Asn Ile Phe Gln Tyr Val Phe
 545                 550                 555                 560
 Gln Lys Lys Met Lys Glu Lys Thr Lys Lys Glu Lys Lys Trp Asn Leu
                 565                 570                 575    
 Gly Asn Thr Arg Ile Lys Pro Glu Lys Gly Lys Glu Asn Met Gly Gly
             580                 585                 590        
 Thr Val Leu Pro Pro Ser Ser Pro Ile Ile Trp Val Glu Tyr Glu Pro
         595                 600                 605            
 Pro Val Ser Ser Pro
     610            



      <210> 2846
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 2846
 Glu Ala Gly Lys Arg Glu Ser Ser Arg Asp Lys Gly Ala Arg Cys Val
   1               5                  10                  15    
 Tyr Thr Arg His Gly Leu Arg Ala Ser Ile Pro Ala Pro Gly Leu Arg
              20                  25                  30        
 Ser Arg Arg Gly Glu Gln Gly Cys Ser Gly Ile Arg Pro Ser Cys Gly
          35                  40                  45            
 Lys Arg Leu Val Cys Pro Gly Cys Arg Asn Gln Glu Asn Pro Glu Gly
      50                  55                  60                
 Asn Arg Gly Lys Gly Ala Ala Arg Phe Thr Arg Glu Ser Ala Ser Gly
  65                  70                  75                  80
 Arg Gly Glu Ser Arg Ser Ala Arg Gly Ser Ile Glu Arg Ser Gly Asp
                  85                  90                  95    
 Met Arg Thr Tyr Trp Leu His Ser Val Trp Val Leu Gly Phe Phe Leu
             100                 105                 110        
 Ser Leu Phe Ser Leu Gln Gly Leu Pro Val Arg Ser Val Asp Phe Asn
         115                 120                 125            
 Arg Gly Thr Asp Asn Ile Thr Val Arg Gln Gly Asp Thr Ala Ile Leu
     130                 135                 140                





      <210> 2847
      <211> 132
      <212> PRT
      <213> Homo sapiens


      <400> 2847
 Gly Gly Gln Gly Val Thr Pro Trp Pro Ser Ser Cys Leu Pro Gly Thr
   1               5                  10                  15    
 Gly Ser Pro Ala Pro Ser Pro Thr Arg Leu Leu Gly Pro Thr Pro Arg
              20                  25                  30        
 Asp Arg Ala Glu Ala Ile Val Gly Pro Asp Ser Ala Thr Cys Ser Gln
          35                  40                  45            
 Thr Glu Gly Ala Gln Glu Gly Gly Arg Cys Leu Pro Pro Gly Met Glu
      50                  55                  60                
 Leu Pro Ala Gly Asp Gly Ala Gly Arg Arg Val Gly Gln Gly Gly Pro
  65                  70                  75                  80
 Glu Gly Gln Leu Gly Gly Gln Gln Arg Gly Lys Gly Ala Gly Pro Gln
                  85                  90                  95    
 Pro Pro Pro Gln Glu Gln Pro Gly Leu Ala Trp Val Gly Asp Arg Leu
             100                 105                 110        
 Ile His Pro Arg Leu Cys Leu Pro Pro Thr Cys Gly His Arg Ala Gly
         115                 120                 125            
 Ser Pro Gly Trp
     130        



      <210> 2848
      <211> 75
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(75)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2848
 Met Asn Ser Leu Ser Trp Gly Ala Ala Asn Ala Val Leu Leu Leu Leu
   1               5                  10                  15    
 Leu Leu Ala Trp Ala Ser Pro Thr Phe Ile Ser Ile Asn Arg Gly Val
              20                  25                  30        
 Arg Val Met Lys Gly Pro Ser Ala Phe Leu Ser Gly Asp Asp Met Lys
          35                  40                  45            
 Phe Ala Ile Pro Lys Glu Lys Asp Ala Cys Cys Ile Arg Glu Ser Ser
      50                  55                  60                
 Thr Arg Xaa Xaa Arg Ser Gly Ser Ala Gly Leu
  65                  70                  75



      <210> 2849
      <211> 142
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(142)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2849
 His Val Ile Lys Val Leu His Asp Asp Trp Ile Phe Thr Pro Phe Ile
   1               5                  10                  15    
 Gln Gly Pro Xaa Ser Met Cys Ser Ser Lys Asn Glu Ser Arg His Ile
              20                  25                  30        
 Gly Ser Xaa Arg Val Thr Gly Xaa Leu Leu Glu Val Leu Lys Ser Leu
          35                  40                  45            
 Leu Xaa Ser Phe Gly Arg Leu Asn Ala Leu Asn Met Lys Ser Leu Thr
      50                  55                  60                
 Ser Glu Val Gln Glu Glu Xaa Arg Lys Leu Asn Lys Thr His Arg Val
  65                  70                  75                  80
 Gln Arg Asp Phe Asp Lys Asp Arg Lys Leu Ala Val Gly Gln Ser Glu
                  85                  90                  95    
 Ser Pro Gly His Pro Thr Ser Glu Lys Pro Pro Ser Thr Ser Ser Ser
             100                 105                 110        
 Ala Gly Cys Met Leu Cys Ser Leu His Ile Ser Arg Gly Phe Gln Leu
         115                 120                 125            
 Arg Arg Lys Arg Gln Leu Asn Gly Lys Cys Cys Pro Ile Gln
     130                 135                 140        



      <210> 2850
      <211> 136
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(136)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2850
 Arg Gln Glu Gly Glu Asp Ser Ala Gly Ser Trp His Ser Gln Gly Pro
   1               5                  10                  15    
 Gly Gln Cys Gln Gly Arg Ala Lys Ala Gly Ser Gly Pro Xaa Xaa Gly
              20                  25                  30        
 Pro Ala Thr Gly Leu Gly Leu Gly Gln Xaa Gln Asp Gln Ser Gln Gly
          35                  40                  45            
 Lys Gly Gln Ser Ser Ala Arg Pro Gly Xaa Gly Gln Ala Phe Gln Gly
      50                  55                  60                
 Gln Gly Gln Gly Arg Thr Arg Ala Arg Ser Glu Ala Gly Lys Gly Gln
  65                  70                  75                  80
 Gly Gln Asp Arg Ser Arg Ala Gly Pro Xaa His Gly Gln Gly Leu Arg
                  85                  90                  95    
 Xaa Gly Lys Gly Arg Ala Arg Ala Arg Xaa Gly Ser Gly Pro Arg Pro
             100                 105                 110        
 Gly Xaa Gly Gln Gly Lys Lys Tyr Gly Arg Thr Arg Gly Asn Ala Lys
         115                 120                 125            
 Ala Lys Ala Gly Pro Gly Leu Thr
     130                 135    



      <210> 2851
      <211> 91
      <212> PRT
      <213> Homo sapiens


      <400> 2851
 Met Trp Leu Leu Pro Ala Leu Leu Leu Leu Cys Leu Ser Gly Cys Leu
   1               5                  10                  15    
 Ser Leu Lys Gly Pro Gly Ser Val Thr Gly Thr Ala Gly Asp Ser Leu
              20                  25                  30        
 Thr Val Trp Cys Gln Tyr Glu Ser Met Tyr Lys Gly Tyr Asn Lys Tyr
          35                  40                  45            
 Trp Cys Arg Gly Gln Tyr Asp Thr Ser Cys Glu Ser Ile Val Glu Thr
      50                  55                  60                
 Thr Gly Glu Glu Lys Gly Gly Lys Glu Trp Pro Arg Val His Gln Arg
  65                  70                  75                  80
 Pro Pro Gly Gly Ser Arg Leu His Cys Asp His
                  85                  90    



      <210> 2852
      <211> 79
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(79)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2852
 Ile Asn Asn Leu Ser Trp Gln Asp Tyr Gly Glu Ser Pro Xaa Ala Leu
   1               5                  10                  15    
 Ser Asn Gln Thr Ser Xaa Val Val Pro Ile Leu Arg Pro Phe Ile Pro
              20                  25                  30        
 Val Phe Leu Leu Leu Leu Phe His Leu Val Phe Gln Phe Ile Gln Asn
          35                  40                  45            
 Arg Ile Gln Ala Ile Thr Asn His Ser Ile Xaa Gln Met Phe Leu Leu
      50                  55                  60                
 Thr Thr Pro Gln Tyr His Pro Leu Pro Gln Asp Leu Pro Ser Ala
  65                  70                  75                



      <210> 2853
      <211> 874
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(874)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2853
 Met Ser Phe Asp Pro Asn Leu Leu His Asn Asn Gly His Asn Gly Tyr
   1               5                  10                  15    
 Pro Asn Gly Thr Ser Ala Ala Leu Arg Glu Thr Gly Val Ile Glu Lys
              20                  25                  30        
 Leu Leu Thr Ser Tyr Gly Phe Ile Gln Cys Ser Glu Arg Gln Ala Arg
          35                  40                  45            
 Leu Phe Phe His Cys Ser Gln Tyr Asn Gly Asn Leu Gln Asp Leu Lys
      50                  55                  60                
 Val Gly Asp Asp Val Glu Phe Glu Val Ser Ser Asp Arg Arg Thr Gly
  65                  70                  75                  80
 Lys Pro Ile Ala Val Lys Leu Val Lys Ile Lys Gln Glu Ile Leu Pro
                  85                  90                  95    
 Glu Glu Arg Met Asn Gly Gln Val Val Cys Ala Val Pro His Asn Leu
             100                 105                 110        
 Glu Ser Lys Ser Pro Ala Ala Pro Gly Gln Ser Pro Thr Gly Ser Val
         115                 120                 125            
 Cys Tyr Glu Arg Asn Gly Glu Val Phe Tyr Leu Thr Tyr Thr Pro Glu
     130                 135                 140                
 Asp Val Glu Gly Asn Val Gln Leu Glu Thr Gly Asp Lys Ile Asn Phe
 145                 150                 155                 160
 Val Ile Asp Asn Asn Lys His Thr Gly Ala Val Ser Ala Arg Asn Ile
                 165                 170                 175    
 Met Leu Leu Lys Lys Lys Gln Ala Arg Cys Gln Gly Val Val Cys Ala
             180                 185                 190        
 Met Lys Glu Ala Phe Gly Phe Ile Glu Arg Gly Asp Val Val Lys Glu
         195                 200                 205            
 Ile Phe Phe His Tyr Ser Glu Phe Lys Gly Asp Leu Glu Thr Leu Gln
     210                 215                 220                
 Pro Gly Asp Asp Val Glu Phe Thr Ile Lys Asp Arg Asn Gly Lys Glu
 225                 230                 235                 240
 Val Ala Thr Asp Val Arg Leu Leu Pro Gln Gly Thr Val Ile Phe Glu
                 245                 250                 255    
 Asp Ile Ser Ile Glu His Phe Glu Gly Thr Val Thr Lys Val Ile Pro
             260                 265                 270        
 Lys Val Pro Ser Lys Asn Gln Asn Asp Pro Leu Pro Gly Arg Ile Lys
         275                 280                 285            
 Val Asp Phe Val Ile Pro Lys Glu Leu Pro Phe Gly Asp Lys Asp Thr
     290                 295                 300                
 Lys Ser Lys Val Thr Leu Leu Glu Gly Asp His Val Arg Phe Asn Ile
 305                 310                 315                 320
 Ser Thr Asp Arg Arg Asp Lys Leu Glu Arg Ala Thr Asn Ile Glu Val
                 325                 330                 335    
 Leu Ser Asn Thr Phe Gln Phe Thr Asn Glu Ala Arg Glu Met Gly Val
             340                 345                 350        
 Ile Ala Ala Met Arg Asp Gly Phe Gly Phe Ile Lys Cys Val Asp Arg
         355                 360                 365            
 Asp Val Arg Met Phe Phe His Phe Ser Glu Ile Leu Asp Gly Asn Gln
     370                 375                 380                
 Leu His Ile Ala Asp Glu Val Glu Phe Thr Val Val Pro Asp Met Leu
 385                 390                 395                 400
 Ser Ala Gln Arg Asn His Ala Ile Arg Ile Lys Lys Leu Pro Lys Gly
                 405                 410                 415    
 Thr Val Ser Phe His Ser His Ser Asp His Arg Phe Leu Gly Thr Val
             420                 425                 430        
 Glu Lys Glu Ala Thr Phe Ser Asn Pro Lys Thr Thr Ser Pro Asn Lys
         435                 440                 445            
 Gly Lys Glu Lys Glu Ala Glu Asp Gly Ile Ile Ala Tyr Asp Asp Cys
     450                 455                 460                
 Gly Val Lys Leu Thr Ile Ala Phe Gln Ala Lys Asp Val Glu Gly Ser
 465                 470                 475                 480
 Thr Ser Pro Gln Ile Gly Asp Lys Val Glu Phe Ser Ile Ser Asp Lys
                 485                 490                 495    
 Gln Arg Pro Gly Gln Gln Val Ala Thr Cys Val Arg Leu Leu Gly Arg
             500                 505                 510        
 Asn Ser Asn Ser Lys Arg Leu Leu Gly Tyr Val Ala Thr Leu Lys Asp
         515                 520                 525            
 Asn Phe Gly Phe Ile Glu Thr Ala Asn His Asp Lys Glu Ile Phe Phe
     530                 535                 540                
 His Tyr Ser Glu Phe Ser Gly Asp Val Asp Ser Leu Glu Leu Gly Asp
 545                 550                 555                 560
 Met Val Glu Tyr Ser Leu Ser Lys Gly Lys Gly Asn Lys Val Ser Ala
                 565                 570                 575    
 Glu Lys Val Asn Lys Thr His Ser Val Asn Gly Ile Thr Glu Glu Ala
             580                 585                 590        
 Asp Pro Thr Ile Tyr Ser Gly Lys Val Ile Arg Pro Leu Arg Ser Val
         595                 600                 605            
 Asp Pro Thr Gln Thr Glu Tyr Gln Gly Met Ile Glu Ile Val Glu Glu
     610                 615                 620                
 Gly Asp Met Lys Gly Glu Val Tyr Pro Phe Gly Ile Val Gly Met Ala
 625                 630                 635                 640
 Asn Lys Gly Asp Cys Leu Gln Lys Gly Glu Ser Val Lys Phe Gln Leu
                 645                 650                 655    
 Cys Val Leu Gly Gln Asn Ala Gln Thr Met Ala Tyr Asn Ile Thr Pro
             660                 665                 670        
 Leu Arg Arg Ala Thr Val Glu Cys Val Lys Asp Gln Phe Gly Phe Ile
         675                 680                 685            
 Asn Tyr Glu Val Gly Asp Ser Lys Lys Leu Phe Phe His Val Lys Glu
     690                 695                 700                
 Val Gln Asp Gly Ile Glu Leu Gln Ala Gly Asp Glu Val Glu Phe Ser
 705                 710                 715                 720
 Val Ile Leu Asn Gln Arg Thr Gly Lys Cys Ser Ala Cys Asn Val Trp
                 725                 730                 735    
 Arg Val Cys Glu Gly Pro Lys Ala Val Ala Ala Pro Arg Pro Asp Arg
             740                 745                 750        
 Leu Val Asn Arg Leu Lys Asn Ile Thr Leu Asp Asp Ala Ser Ala Pro
         755                 760                 765            
 Arg Leu Met Val Leu Arg Gln Pro Arg Gly Pro Asp Asn Ser Met Gly
     770                 775                 780                
 Phe Gly Ala Glu Arg Lys Ile Arg Gln Ala Gly Val Ile Asp Xaa Asn
 785                 790                 795                 800
 Trp Arg Lys Gln Lys Cys Phe Val Phe Thr Lys Ile Asn Gly Leu Phe
                 805                 810                 815    
 Thr Gln Arg Ser Lys Pro Gln Thr Thr Arg Gly Lys Ile Lys Pro Pro
             820                 825                 830        
 Ser Pro Thr Ser Pro Glu Leu Thr Leu Val Ile Leu Asp Lys Ala Phe
         835                 840                 845            
 Ser Pro Leu Ala Arg Asp Pro Val Tyr Gly Gln Phe Lys Lys Arg Ala
     850                 855                 860                
 Lys Lys Ser Asp Pro Ser Ile Pro Val Ile
 865                 870                



      <210> 2854
      <211> 248
      <212> PRT
      <213> Homo sapiens


      <400> 2854
 Met Arg Leu Gln Arg Pro Arg Gln Ala Pro Ala Gly Gly Arg Arg Ala
   1               5                  10                  15    
 Pro Arg Gly Gly Arg Gly Ser Pro Tyr Arg Pro Asp Pro Gly Arg Gly
              20                  25                  30        
 Ala Arg Arg Leu Arg Arg Phe Gln Lys Gly Gly Glu Gly Ala Pro Arg
          35                  40                  45            
 Ala Asp Pro Pro Trp Ala Pro Leu Gly Thr Met Ala Leu Leu Ala Leu
      50                  55                  60                
 Leu Leu Val Val Ala Leu Pro Arg Val Trp Thr Asp Ala Asn Leu Thr
  65                  70                  75                  80
 Ala Arg Gln Arg Asp Pro Glu Asp Ser Gln Arg Thr Asp Glu Gly Asp
                  85                  90                  95    
 Asn Arg Val Trp Cys His Val Cys Glu Arg Glu Asn Thr Phe Glu Cys
             100                 105                 110        
 Gln Asn Pro Arg Arg Cys Lys Trp Thr Glu Pro Tyr Cys Val Ile Ala
         115                 120                 125            
 Ala Val Lys Ile Phe Pro Arg Phe Phe Met Val Ala Lys Gln Cys Ser
     130                 135                 140                
 Ala Gly Cys Ala Ala Met Glu Arg Pro Lys Pro Glu Glu Lys Arg Phe
 145                 150                 155                 160
 Leu Leu Glu Glu Pro Met Pro Phe Phe Tyr Leu Lys Cys Cys Lys Ile
                 165                 170                 175    
 Arg Tyr Cys Asn Leu Gly Gly Ala Asn Leu Ser Thr His Gln Cys Ser
             180                 185                 190        
 Lys Asn Met Leu Gly Ala Trp Val Arg Ala Val Val Gly Cys Gly Trp
         195                 200                 205            
 Pro Ser Ser Cys Cys Trp Pro Pro Leu Gln Pro Ala Ser Ala Cys Leu
     210                 215                 220                
 Glu Pro Arg Asp Cys His Arg Leu Ser Leu Pro Glu His Gly Leu Ala
 225                 230                 235                 240
 Pro Asp Arg Cys His Leu Leu His
                 245            



      <210> 2855
      <211> 338
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(338)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2855
 Phe Ala Ser Phe Pro Ser Ile Asn Leu Gln Gln Met Leu Lys Glu Val
   1               5                  10                  15    
 Pro Lys Arg Phe Gly Asp Glu Arg Gly Ala Ile Val His Tyr Thr Ile
              20                  25                  30        
 Leu Asn Asn His Val Tyr Arg Arg Ser Leu Gly Lys Tyr Thr Asp Phe
          35                  40                  45            
 Lys Met Phe Ser Asp Glu Ile Leu Leu Ser Leu Thr Arg Lys Val Leu
      50                  55                  60                
 Leu Pro Asp Leu Glu Phe Tyr Val Asn Leu Gly Asp Trp Pro Leu Glu
  65                  70                  75                  80
 His Arg Lys Val Asn Gly Thr Pro Ser Pro Ile Pro Ile Ile Ser Trp
                  85                  90                  95    
 Cys Gly Ser Leu Asp Ser Arg Asp Val Val Leu Pro Thr Tyr Asp Ile
             100                 105                 110        
 Thr His Ser Met Leu Glu Ala Met Arg Gly Val Thr Asn Asp Leu Leu
         115                 120                 125            
 Ser Ile Gln Gly Asn Thr Gly Pro Ser Trp Ile Asn Lys Thr Glu Arg
     130                 135                 140                
 Ala Phe Phe Arg Gly Arg Asp Ser Arg Glu Glu Arg Leu Gln Leu Val
 145                 150                 155                 160
 Gln Leu Ser Lys Glu Asn Pro Gln Leu Leu Asp Ala Trp Asn Tyr Arg
                 165                 170                 175    
 Ile Phe Leu Phe Pro Arg Glu Arg Lys Gly Ala Xaa Lys Ala Lys Leu
             180                 185                 190        
 Met Gly Leu Leu Asp Thr Cys Thr Xaa Arg Asn Val Asp Gly Thr Val
         195                 200                 205            
 Ala Ala Tyr Arg Tyr Pro Tyr Leu Met Leu Gly Asp Ser Leu Val Leu
     210                 215                 220                
 Lys Gln Asp Ser Pro Tyr Tyr Glu His Phe Tyr Met Ala Leu Glu Pro
 225                 230                 235                 240
 Trp Lys His Tyr Val Pro Ile Lys Arg Asn Leu Ser Asp Leu Leu Glu
                 245                 250                 255    
 Lys Val Lys Trp Ala Lys Glu Asn Asp Glu Glu Ala Lys Lys Ile Ala
             260                 265                 270        
 Lys Glu Gly Gln Leu Met Ala Arg Asp Leu Leu Gln Pro His Arg Leu
         275                 280                 285            
 Tyr Cys Tyr Tyr Tyr Gln Val Leu Gln Lys Tyr Ala Glu Arg Gln Ser
     290                 295                 300                
 Ser Lys Pro Glu Val Arg Asp Gly Met Glu Leu Val Pro Gln Pro Glu
 305                 310                 315                 320
 Asp Ser Thr Ala Ile Cys Gln Cys His Arg Lys Lys Pro Ser Arg Glu
                 325                 330                 335    
 Glu Leu
        



      <210> 2856
      <211> 1233
      <212> PRT
      <213> Homo sapiens


      <400> 2856
 Arg Ala Gly Glu Val Val Pro Gly Trp Leu Leu Ala Ala Ala Ala Ala
   1               5                  10                  15    
 His Pro Gly Arg Pro Ala Ala Ser Leu Ser Pro Gly Leu Gly Ala Val
              20                  25                  30        
 Leu Gly Val Ala Gly Arg Gln Val Ala Asp Pro Arg Phe Arg Arg Asp
          35                  40                  45            
 Trp Phe Arg Ile Pro Ser Pro Pro Ala Glu Ser Ala Gly Pro Ala Arg
      50                  55                  60                
 Gln Ala Gly Phe Ala Ala Ala Pro Pro Ala Arg Ala Gly Pro Ala Leu
  65                  70                  75                  80
 Ser Thr Met Lys Gly Thr Arg Ala Ile Gly Ser Val Pro Glu Arg Ser
                  85                  90                  95    
 Pro Ala Gly Val Asp Leu Ser Leu Thr Gly Leu Pro Pro Pro Val Ser
             100                 105                 110        
 Arg Arg Pro Gly Ser Ala Ala Thr Thr Lys Pro Ile Val Arg Ser Val
         115                 120                 125            
 Ser Val Val Thr Gly Ser Glu Gln Lys Arg Lys Val Leu Glu Ala Thr
     130                 135                 140                
 Gly Pro Gly Gly Ser Gln Ala Ile Asn Asn Leu Arg Arg Ser Asn Ser
 145                 150                 155                 160
 Thr Thr Gln Val Ser Gln Pro Arg Ser Gly Ser Pro Arg Pro Thr Glu
                 165                 170                 175    
 Pro Thr Asp Phe Leu Met Leu Phe Glu Gly Ser Pro Ser Gly Lys Lys
             180                 185                 190        
 Arg Pro Ala Ser Leu Ser Thr Ala Pro Ser Glu Lys Gly Ala Thr Trp
         195                 200                 205            
 Asn Val Leu Asp Asp Gln Pro Arg Gly Phe Thr Leu Pro Ser Asn Ala
     210                 215                 220                
 Arg Ser Ser Ser Ala Leu Asp Ser Pro Ala Gly Pro Arg Arg Lys Glu
 225                 230                 235                 240
 Cys Thr Val Ala Leu Ala Pro Asn Phe Thr Ala Asn Asn Arg Ser Asn
                 245                 250                 255    
 Lys Gly Ala Val Gly Asn Cys Val Thr Thr Met Val His Asn Arg Tyr
             260                 265                 270        
 Thr Pro Ser Glu Arg Ala Pro Pro Leu Lys Ser Ser Asn Gln Thr Ala
         275                 280                 285            
 Pro Ser Leu Asn Asn Ile Ile Lys Ala Ala Thr Cys Glu Gly Ser Glu
     290                 295                 300                
 Ser Ser Gly Phe Gly Lys Leu Pro Lys Asn Val Ser Ser Ala Thr His
 305                 310                 315                 320
 Ser Ala Arg Asn Asn Thr Gly Gly Ser Thr Gly Leu Pro Arg Arg Lys
                 325                 330                 335    
 Glu Val Thr Glu Glu Glu Ala Glu Arg Phe Ile His Gln Val Asn Gln
             340                 345                 350        
 Ala Ala Val Thr Ile Gln Arg Trp Tyr Arg His Gln Val Gln Arg Arg
         355                 360                 365            
 Gly Ala Gly Ala Ala Arg Leu Glu His Leu Leu Gln Ala Lys Arg Glu
     370                 375                 380                
 Glu Gln Arg Gln Arg Ser Gly Glu Gly Thr Leu Leu Asp Leu His Gln
 385                 390                 395                 400
 Gln Lys Glu Ala Ala Arg Arg Lys Ala Arg Glu Glu Lys Ala Arg Gln
                 405                 410                 415    
 Ala Arg Arg Ala Ala Ile Gln Glu Leu Gln Gln Lys Arg Ala Leu Arg
             420                 425                 430        
 Ala Gln Lys Ala Ser Thr Ala Glu Arg Gly Pro Pro Glu Asn Pro Arg
         435                 440                 445            
 Glu Thr Arg Val Pro Gly Met Arg Gln Pro Ala Gln Glu Leu Ser Pro
     450                 455                 460                
 Thr Pro Gly Gly Thr Ala His Gln Ala Leu Lys Ala Asn Asn Ala Gly
 465                 470                 475                 480
 Gly Gly Leu Pro Ala Ala Gly Pro Gly Asp Arg Cys Leu Pro Thr Ser
                 485                 490                 495    
 Asp Ser Ser Pro Glu Pro Gln Gln Pro Pro Glu Asp Arg Thr Gln Asp
             500                 505                 510        
 Val Leu Ala Gln Asp Ala Ala Gly Asp Asn Leu Glu Met Met Ala Pro
         515                 520                 525            
 Ser Arg Gly Ser Ala Lys Ser Arg Gly Pro Leu Glu Glu Leu Leu His
     530                 535                 540                
 Thr Leu Gln Leu Leu Glu Lys Glu Pro Asp Ala Leu Pro Arg Pro Arg
 545                 550                 555                 560
 Thr His His Arg Gly Arg Tyr Ala Trp Ala Ser Glu Val Thr Thr Glu
                 565                 570                 575    
 Asp Asp Ala Ser Ser Leu Thr Ala Asp Asn Leu Glu Lys Phe Gly Lys
             580                 585                 590        
 Leu Ser Ala Phe Pro Glu Pro Pro Glu Asp Gly Thr Leu Leu Ser Glu
         595                 600                 605            
 Ala Lys Leu Gln Ser Ile Met Ser Phe Leu Asp Glu Met Glu Lys Ser
     610                 615                 620                
 Gly Gln Asp Gln Leu Asp Ser Gln Gln Glu Gly Trp Val Pro Glu Ala
 625                 630                 635                 640
 Gly Pro Gly Pro Leu Glu Leu Gly Ser Glu Val Ser Thr Ser Val Met
                 645                 650                 655    
 Arg Leu Lys Leu Glu Val Glu Glu Lys Lys Gln Ala Met Leu Leu Leu
             660                 665                 670        
 Gln Arg Ala Leu Ala Gln Gln Arg Asp Leu Thr Ala Arg Arg Val Lys
         675                 680                 685            
 Glu Thr Glu Lys Ala Leu Ser Arg Gln Leu Gln Arg Gln Lys Glu Ala
     690                 695                 700                
 Tyr Glu Ala Thr Ile Gln Arg His Leu Ala Phe Ile Asp Gln Leu Ile
 705                 710                 715                 720
 Glu Asp Lys Lys Val Leu Ser Glu Lys Cys Glu Ala Val Val Ala Glu
                 725                 730                 735    
 Leu Lys Gln Glu Asp Gln Arg Cys Thr Glu Arg Val Ala Gln Ala Gln
             740                 745                 750        
 Ala Gln His Glu Leu Glu Ile Lys Lys Leu Lys Glu Leu Met Ser Ala
         755                 760                 765            
 Thr Glu Lys Ala Arg Arg Glu Lys Trp Ile Ser Glu Lys Thr Lys Lys
     770                 775                 780                
 Ile Lys Glu Val Thr Val Arg Gly Leu Glu Pro Glu Ile Gln Lys Leu
 785                 790                 795                 800
 Ile Ala Arg His Lys Gln Glu Val Arg Arg Leu Lys Ser Leu His Glu
                 805                 810                 815    
 Ala Glu Leu Leu Gln Ser Asp Glu Arg Ala Ser Gln Arg Cys Leu Arg
             820                 825                 830        
 Gln Ala Glu Glu Leu Arg Glu Gln Leu Glu Arg Glu Lys Glu Ala Leu
         835                 840                 845            
 Gly Gln Gln Glu Arg Glu Arg Ala Arg Gln Arg Phe Gln Gln His Leu
     850                 855                 860                
 Glu Gln Glu Gln Trp Ala Leu Gln Gln Gln Arg Gln Arg Leu Tyr Ser
 865                 870                 875                 880
 Glu Val Ala Glu Glu Arg Glu Arg Leu Gly Gln Gln Ala Ala Arg Gln
                 885                 890                 895    
 Arg Ala Glu Leu Glu Glu Leu Arg Gln Gln Leu Glu Glu Ser Ser Ser
             900                 905                 910        
 Ala Leu Thr Arg Ala Leu Arg Ala Glu Phe Glu Lys Gly Arg Glu Glu
         915                 920                 925            
 Gln Glu Arg Arg His Gln Met Glu Leu Asn Thr Leu Lys Gln Gln Leu
     930                 935                 940                
 Glu Leu Glu Arg Gln Ala Trp Glu Ala Gly Arg Thr Arg Lys Glu Glu
 945                 950                 955                 960
 Ala Trp Leu Leu Asn Arg Glu Gln Glu Leu Arg Glu Glu Ile Arg Lys
                 965                 970                 975    
 Gly Arg Asp Lys Glu Ile Glu Leu Val Ile His Arg Leu Glu Ala Asp
             980                 985                 990        
 Met Ala Leu Ala Lys Glu Glu Ser Glu Lys Ala Ala Glu Ser Arg Ile
         995                1000                1005            
 Lys Arg Leu Arg Asp Lys Tyr Glu Ala Glu Leu Ser Glu Leu Glu Gln
    1010                1015                1020                
 Ser Glu Arg Lys Leu Gln Glu Arg Cys Ser Glu Leu Lys Gly Gln Leu
1025                1030                1035                1040
 Gly Glu Ala Glu Gly Glu Asn Leu Arg Leu Gln Gly Leu Val Arg Gln
                1045                1050                1055    
 Lys Glu Arg Ala Leu Glu Asp Ala Gln Ala Val Asn Glu Gln Leu Ser
            1060                1065                1070        
 Ser Glu Arg Ser Asn Leu Ala Gln Val Ile Arg Gln Glu Phe Glu Asp
        1075                1080                1085            
 Arg Leu Ala Ala Ser Glu Glu Glu Thr Arg Gln Ala Lys Ala Glu Leu
    1090                1095                1100                
 Ala Thr Leu Gln Ala Arg Gln Gln Leu Glu Leu Glu Glu Val His Arg
1105                1110                1115                1120
 Arg Val Lys Thr Ala Leu Ala Arg Lys Glu Glu Ala Val Ser Ser Leu
                1125                1130                1135    
 Arg Thr Gln His Lys Gly Ser Val Lys Arg Ala Asp His Leu Glu Glu
            1140                1145                1150        
 Leu Leu Lys Gln His Arg Arg Pro Thr Pro Ser Thr Lys Cys Pro Gly
        1155                1160                1165            
 Met Pro Gly Thr Leu Phe Lys Asn Gly Arg Gln Arg Thr Lys Ala Gly
    1170                1175                1180                
 Arg Gly Pro Arg Gly Pro Gln Gly Arg Pro Pro Ala Pro His Arg Gly
1185                1190                1195                1200
 Trp Trp Leu Arg Cys Pro Arg Leu Ser Thr Cys Gly Cys Ile Leu Thr
                1205                1210                1215    
 Val Lys Glu Ala Val Val Phe Ser Lys Lys Lys Lys Lys Gly Ala Pro
            1220                1225                1230        
 Phe
    



      <210> 2857
      <211> 687
      <212> PRT
      <213> Homo sapiens


      <400> 2857
 Met Thr Ala Ser Ile Arg Arg Tyr His Thr Cys Ala Thr Asp Gly Glu
   1               5                  10                  15    
 Pro Asp Ser Ser Val Leu Val Gly Gly Asp Gly Asp Leu Thr Leu Leu
              20                  25                  30        
 Val Ala Ala Leu Gly Leu Asp Leu Gly Leu Pro Phe Met Leu Leu Pro
          35                  40                  45            
 Pro Leu Met Glu Trp Met Arg Val Ala Ile Thr Tyr Ala Glu His Arg
      50                  55                  60                
 Arg Ser Leu Thr Val Asp Ser Gly Asp Ile Arg Gln Ala Ala Arg Leu
  65                  70                  75                  80
 Leu Leu Pro Gly Pro Glu His Cys Phe Ser Ser Phe Arg Arg Leu Asp
                  85                  90                  95    
 Ala Arg Ala Ala Thr Glu Lys Phe Asn Gln Asp Leu Gly Phe Arg Met
             100                 105                 110        
 Leu Asn Cys Gly Arg Thr Asp Leu Ile Asn Gln Ala Ile Glu Ala Leu
         115                 120                 125            
 Gly Pro Asp Gly Val Asn Thr Met Asp Asp Gln Gly Met Thr Pro Leu
     130                 135                 140                
 Met Tyr Ala Cys Ala Ala Gly Asp Glu Ala Met Val Gln Met Leu Ile
 145                 150                 155                 160
 Asp Ala Gly Ala Asn Leu Asp Ile Gln Val Pro Ser Asn Ser Pro Arg
                 165                 170                 175    
 His Pro Ser Ile His Pro Asp Ser Arg His Trp Thr Ser Leu Thr Phe
             180                 185                 190        
 Ala Val Leu His Gly His Ile Ser Val Val Gln Leu Leu Leu Asp Ala
         195                 200                 205            
 Gly Ala His Val Glu Gly Ser Ala Val Asn Gly Gly Glu Asp Ser Tyr
     210                 215                 220                
 Ala Glu Thr Pro Leu Gln Leu Ala Ser Ala Ala Gly Asn Tyr Glu Leu
 225                 230                 235                 240
 Val Ser Leu Leu Leu Ser Arg Gly Ala Asp Pro Leu Leu Ser Met Leu
                 245                 250                 255    
 Glu Ala His Gly Met Gly Ser Ser Leu His Glu Asp Met Asn Cys Phe
             260                 265                 270        
 Ser His Ser Ala Ala His Gly His Arg Gly Ile Trp Gly Leu Val Thr
         275                 280                 285            
 Leu Gly Pro Leu Ala Cys Leu Glu Glu Glu Asp His Glu Thr Pro Ser
     290                 295                 300                
 Pro Arg Val Pro Gln Ser Ser Pro Ser Gly Gln Glu Gly Thr Gly Gly
 305                 310                 315                 320
 Gln Leu Arg Asn Val Leu Arg Lys Leu Leu Thr Gln Pro Gln Gln Ala
                 325                 330                 335    
 Lys Ala Asp Val Leu Ser Leu Glu Glu Ile Leu Ala Glu Gly Val Glu
             340                 345                 350        
 Glu Ser Asp Ala Ser Ser Gln Gly Ser Gly Ser Glu Gly Pro Val Arg
         355                 360                 365            
 Leu Ser Arg Thr Arg Thr Lys Ala Leu Gln Glu Ala Met Tyr Tyr Ser
     370                 375                 380                
 Ala Glu His Gly Tyr Val Asp Ile Thr Met Glu Leu Arg Ala Leu Gly
 385                 390                 395                 400
 Val Pro Trp Lys Leu His Ile Trp Ile Glu Ser Leu Arg Thr Ser Phe
                 405                 410                 415    
 Ser Gln Ser Arg Tyr Ser Val Val Gln Ser Leu Leu Arg Asp Phe Ser
             420                 425                 430        
 Ser Ile Arg Glu Glu Glu Tyr Asn Glu Glu Leu Val Thr Glu Gly Leu
         435                 440                 445            
 Gln Leu Met Phe Asp Ile Leu Lys Thr Ser Lys Asn Asp Ser Val Ile
     450                 455                 460                
 Gln Gln Leu Ala Thr Ile Phe Thr His Cys Tyr Gly Ser Ser Pro Ile
 465                 470                 475                 480
 Pro Ser Ile Pro Glu Ile Arg Lys Thr Leu Pro Ala Arg Leu Asp Pro
                 485                 490                 495    
 His Phe Leu Asn Asn Lys Glu Met Ser Asp Val Thr Phe Leu Val Glu
             500                 505                 510        
 Gly Lys Leu Phe Tyr Ala His Lys Val Leu Leu Val Thr Ala Ser Asn
         515                 520                 525            
 Arg Phe Lys Thr Leu Met Thr Asn Lys Ser Glu Gln Asp Gly Asp Ser
     530                 535                 540                
 Ser Lys Thr Ile Glu Ile Ser Asp Met Lys Tyr His Ile Phe Gln Met
 545                 550                 555                 560
 Met Met Gln Tyr Leu Tyr Tyr Gly Gly Thr Glu Ser Met Glu Ile Pro
                 565                 570                 575    
 Thr Thr Asp Ile Leu Glu Leu Leu Ser Ala Ala Ser Leu Phe Gln Leu
             580                 585                 590        
 Asp Ala Leu Gln Arg His Cys Glu Ile Leu Cys Ser Gln Thr Leu Ser
         595                 600                 605            
 Met Glu Ser Ala Val Asn Thr Tyr Lys Tyr Ala Lys Ile His Asn Ala
     610                 615                 620                
 Pro Glu Leu Ala Leu Phe Cys Glu Gly Phe Phe Leu Lys His Met Lys
 625                 630                 635                 640
 Ala Leu Leu Glu Gln Met Pro Ser Gly Ser Ser Ser Thr Ala Ala Ala
                 645                 650                 655    
 Ala Lys Cys Arg Ala Trp Ile His Cys Arg Thr Cys Arg Thr Pro Trp
             660                 665                 670        
 Gln Ser Ala Cys Thr Leu Ser Thr Ser Pro Pro Gly Ser Ala Ala
         675                 680                 685        



      <210> 2858
      <211> 190
      <212> PRT
      <213> Homo sapiens


      <400> 2858
 Phe Arg Pro Gly Arg Arg Ala Lys Arg Ala Met Ala Val Tyr Val Gly
   1               5                  10                  15    
 Met Leu Arg Leu Gly Arg Leu Cys Ala Gly Ser Ser Gly Val Leu Gly
              20                  25                  30        
 Ala Arg Ala Ala Leu Ser Arg Ser Trp Gln Glu Ala Arg Leu Gln Gly
          35                  40                  45            
 Val Arg Phe Leu Ser Ser Arg Glu Val Asp Arg Met Val Ser Thr Pro
      50                  55                  60                
 Ile Gly Gly Leu Ser Tyr Val Gln Gly Cys Thr Lys Lys His Leu Asn
  65                  70                  75                  80
 Ser Lys Thr Val Gly Gln Cys Leu Glu Thr Thr Ala Gln Arg Val Pro
                  85                  90                  95    
 Glu Arg Glu Ala Leu Val Val Leu His Glu Asp Val Arg Leu Thr Phe
             100                 105                 110        
 Ala Gln Leu Lys Glu Glu Val Asp Lys Ala Ala Ser Gly Leu Leu Ser
         115                 120                 125            
 Ile Gly Leu Cys Lys Gly Asp Arg Leu Gly Met Trp Gly Pro Asn Ser
     130                 135                 140                
 Tyr Ala Trp Val Leu Met Gln Leu Ala Thr Ala Gln Ala Gly Ile Ile
 145                 150                 155                 160
 Leu Val Ser Val Asn Pro Ala Tyr Gln Ala Met Glu Leu Glu Tyr Val
                 165                 170                 175    
 Leu Lys Lys Val Gly Cys Lys Ala Leu Val Phe Pro Lys Gln
             180                 185                 190



      <210> 2859
      <211> 45
      <212> PRT
      <213> Homo sapiens


      <400> 2859
 Met Cys Cys Trp Ile Trp Phe Ala Ser Ile Leu Leu Arg Ile Phe Ala
   1               5                  10                  15    
 Leu Met Phe Ile Arg Asp Ile Gly Leu Lys Phe Ser Phe Phe Val Val
              20                  25                  30        
 Ser Leu Pro Gly Phe Gly Ile Arg Met Met Leu Ala Ser
          35                  40                  45



      <210> 2860
      <211> 451
      <212> PRT
      <213> Homo sapiens


      <400> 2860
 Met Val Lys Leu Ser Ile Val Leu Thr Pro Gln Phe Leu Ser His Asp
   1               5                  10                  15    
 Gln Gly Gln Leu Thr Lys Glu Leu Gln Gln His Val Lys Ser Val Thr
              20                  25                  30        
 Cys Pro Cys Glu Tyr Leu Arg Lys Val Ser Leu Leu Lys Thr Ile Phe
          35                  40                  45            
 Trp Ser Arg Asn Gly His Asp Gly Ser Thr Asp Val Gln Gln Arg Ala
      50                  55                  60                
 Trp Arg Ser Asn Arg Arg Arg Gln Glu Gly Leu Arg Ser Ile Cys Met
  65                  70                  75                  80
 His Thr Lys Lys Arg Val Ser Ser Phe Arg Gly Asn Lys Ile Gly Leu
                  85                  90                  95    
 Lys Asp Val Ile Thr Leu Arg Arg His Val Glu Thr Lys Val Arg Ala
             100                 105                 110        
 Lys Ile Arg Lys Arg Lys Val Thr Thr Lys Ile Asn His His Asp Lys
         115                 120                 125            
 Ile Asn Gly Lys Arg Lys Thr Ala Arg Lys His Thr Gly Asp Cys His
     130                 135                 140                
 Pro Gly Glu Val Val Gly Gln Ala His Phe Val Pro Asp Ser Pro Val
 145                 150                 155                 160
 His Ile Ala Leu His Gly Met Ala Gln Pro Leu Phe Gly Ile Gln Gly
                 165                 170                 175    
 Gly Ala Leu Glu Pro Ala Gly Arg Gly Thr Gly Phe Leu Asp Ser Pro
             180                 185                 190        
 Val Phe Arg Pro Ile Arg Lys Tyr Asn Val Gln Ile Pro Pro Ser Ala
         195                 200                 205            
 Arg Lys Ala Leu Cys Asn Trp Ser Leu Leu Leu Val Cys Val Gly Lys
     210                 215                 220                
 Pro Glu Ile Phe Val Ala Ile His Tyr Tyr Thr Pro Asn Thr Lys Leu
 225                 230                 235                 240
 Val Pro Leu Ala Arg Pro Arg Asn Ser His Val Pro His Pro Pro Glu
                 245                 250                 255    
 Arg Thr Thr Val Thr Gln Tyr Ser Thr Cys Ala Leu Leu Thr Ala Leu
             260                 265                 270        
 Cys Leu Leu Leu Pro Val Leu Gln Glu Thr Ala Gln Ser Arg Arg Met
         275                 280                 285            
 Val Thr Ser His Pro Glu Asp Ser Pro Ala Leu Ala Arg Lys His Gly
     290                 295                 300                
 Ala Ser Gln Pro Ala Gly Leu Gly Phe Pro Arg Thr Gln Thr Val Thr
 305                 310                 315                 320
 Pro Ala Phe Thr Phe Gln Thr Pro Thr Ala Ala Glu Pro Ala Leu Leu
                 325                 330                 335    
 Ser Ala Trp Leu Gly Arg Ala Pro Glu Thr Glu Thr Ile Thr Asp Met
             340                 345                 350        
 Ala Gly Ser Ala Ala Ala Ala Pro Thr Cys Glu Met Leu Arg Ala His
         355                 360                 365            
 Gly His Asp Asp Leu Tyr Phe Lys Trp Glu Pro Cys Ala Ser Ser Gln
     370                 375                 380                
 Ala Ile Thr Val Leu Pro Lys His Ser Gly Thr Gly Gly Ser Arg Gln
 385                 390                 395                 400
 Gly Pro Ala Val Ala His Pro Ala Ala Pro Phe Pro Lys Val Arg Gly
                 405                 410                 415    
 Gly Glu Gly Thr Tyr Tyr Leu His Leu Ser Val Phe Ser Asp Leu Val
             420                 425                 430        
 Asp Leu His Leu Leu His Val Gly Gln Arg Val Val Gln Gly Leu Arg
         435                 440                 445            
 Leu Arg Leu
     450    



      <210> 2861
      <211> 114
      <212> PRT
      <213> Homo sapiens


      <400> 2861
 Cys Ser Ser Phe Cys Phe Pro Phe Pro Arg Ser Arg Pro Thr Ala Pro
   1               5                  10                  15    
 Arg Pro Asp His Arg Pro Ala Glu Pro Gln Arg Leu His Ser Ala Glu
              20                  25                  30        
 Gly Ala Pro Glu Val Val Gly Pro Thr Ser Asp Pro His His His Pro
          35                  40                  45            
 Cys Pro Gly Gly Ala Pro Gly Gly Thr Gln Asp Pro Lys Met Ala Ala
      50                  55                  60                
 Glu Ala Pro Gln Gln Pro Asn Ser Asp Trp Ala Gly Glu Ile Ser Met
  65                  70                  75                  80
 Cys Arg Gly Ser Thr His Gln Leu Gln Met Ala Phe Ser Glu Thr Phe
                  85                  90                  95    
 Leu Ser Ala Leu Ser Gly Ser Ser Arg Gly Arg Pro Ala Gly Lys Glu
             100                 105                 110        
 Ser Cys
        



      <210> 2862
      <211> 123
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(123)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2862
 Ser Gly Leu Phe Leu Phe Phe Phe Pro Phe Pro Pro Phe Leu Pro Leu
   1               5                  10                  15    
 Pro Leu Cys Lys His Gln Ile Arg Asp Glu Trp Gly Asn Gln Ile Trp
              20                  25                  30        
 Ile Cys Pro Gly Cys Asn Lys Pro Asp Asp Gly Ser Pro Met Ile Gly
          35                  40                  45            
 Cys Asp Asp Cys Asp Asp Trp Tyr His Trp Pro Cys Val Gly Ile Met
      50                  55                  60                
 Thr Ala Pro Pro Glu Glu Met Gln Trp Phe Cys Pro Lys Cys Ala Asn
  65                  70                  75                  80
 Lys Lys Lys Asp Lys Lys His Lys Lys Arg Lys His Arg Ala His Xaa
                  85                  90                  95    
 Arg Asp Asp Tyr Lys Met Leu Phe Met Thr Tyr Lys Arg Lys Leu Arg
             100                 105                 110        
 Ile Phe Val Arg Asn Ala Leu Ser Leu Asn Thr
         115                 120            



      <210> 2863
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 2863
 Leu Val Asp Pro Arg Val Arg Ala Val Phe Leu Gln Leu Leu Pro Leu
   1               5                  10                  15    
 Leu Leu Ser Arg Ala Gln Gly Asn Pro Gly Ala Ser Leu Asp Gly Arg
              20                  25                  30        
 Pro Gly Asp Arg Val Asn Leu Ser Cys Gly Gly Val Ser His Pro Ile
          35                  40                  45            
 Arg Trp Val Trp Ala Pro Ser Phe Pro Ala Cys Lys Gly Leu Ser Lys
      50                  55                  60                
 Gly Arg Arg Pro Ile Leu Trp Ala Ser Ser Ser Gly Thr Pro Thr Val
  65                  70                  75                  80
 Pro Pro Leu Gln Pro Phe Val Gly Arg Leu Arg Ser Leu Asp Ser Gly
                  85                  90                  95    
 Ile Arg Arg Leu Glu Leu Leu Leu Ser Ala Gly Asp Ser Gly Thr Phe
             100                 105                 110        
 Phe Cys Lys Gly Arg His Glu Asp Glu Ser Arg Thr Val Leu His Val
         115                 120                 125            
 Leu Gly Asp Arg Thr Tyr Cys Lys Ala Pro Gly Pro Thr His Gly Ser
     130                 135                 140                
 Val Tyr Pro Gln Leu Leu Ile Pro Leu Leu Gly Ala Gly Leu Val Leu
 145                 150                 155                 160
 Gly Leu Gly Ala Leu Gly Leu Val Trp Trp Leu His
                 165                 170        



      <210> 2864
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 2864
 Arg Thr Arg Gly Arg Thr Arg Gly Leu Val Ile Lys Lys Trp Ala Ser
   1               5                  10                  15    
 His His Gln Ile Asn Asp Ala Ser Arg Gly Thr Leu Ser Ser Tyr Ser
              20                  25                  30        
 Leu Val Leu Met Val Leu His Tyr Leu Gln Thr Leu Pro Glu Pro Ile
          35                  40                  45            
 Leu Pro Ser Leu Gln Lys Ile Tyr Pro Glu Ser Phe Ser Pro Ala Ile
      50                  55                  60                
 Gln Leu His Leu Val His Gln Ala Pro Cys Asn Val Pro Pro Tyr Leu
  65                  70                  75                  80
 Ser Lys Asn Glu Ser Asn Leu Gly Asp Leu Leu Leu Gly Phe Leu Lys
                  85                  90                  95    
 Tyr Tyr Ala Thr Glu Phe Asp Trp Asn Ser Gln Met Ile Ser Val Arg
             100                 105                 110        
 Glu Ala Lys Ala Ile Pro Arg Pro Asp Gly Ile Glu Trp Arg Asn Lys
         115                 120                 125            
 Tyr Ile Cys Val Glu Glu Pro Phe Asp Gly Thr Asn Thr Ala Arg Ala
     130                 135                 140                
 Val His Glu Lys Gln Lys Phe Asp Met Ile Lys Asp Gln Phe Leu Lys
 145                 150                 155                 160
 Ser Trp His Arg Leu Lys Asn Lys Arg Asp Leu Asn Ser Ile Leu Pro
                 165                 170                 175    
 Val Arg Ala Ala Val Leu Lys Arg
             180                



      <210> 2865
      <211> 110
      <212> PRT
      <213> Homo sapiens


      <400> 2865
 Met Trp Ser Leu Trp Ile Trp Val Asp Gln His Gln Ala Arg Leu Ile
   1               5                  10                  15    
 Pro Ser Pro Gln Val Leu Leu Leu Leu Leu Arg Glu Thr Pro Ser Thr
              20                  25                  30        
 Ala Ala Ala Val Ala Gly Trp Leu Val Val Ala Ser Met Ala Leu Leu
          35                  40                  45            
 Gln Leu His Ala Val Gly Gly Val Ala Leu Thr Ser Ser His Pro Phe
      50                  55                  60                
 Met Trp Ala Thr Gly Glu Glu Leu Arg Lys Pro Pro Trp Gln Gly Ser
  65                  70                  75                  80
 Ala Gly Ser Ala Ser Gly Val Glu Glu Leu Thr Gly Lys His Ser Cys
                  85                  90                  95    
 Pro Gly Pro Glu Glu Pro Ala Thr Val Gln Lys Ala Pro Ala
             100                 105                 110



      <210> 2866
      <211> 223
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(223)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2866
 Thr Phe Thr Gln Pro Asp Pro Asp Asp Leu Ile Ser Lys Pro Pro Arg
   1               5                  10                  15    
 Thr Pro Gly Gly Gly Xaa Tyr Gln Thr Gln Trp Pro Ser Pro Pro Asp
              20                  25                  30        
 Pro Arg Arg Thr Ser Pro Ala Gly Arg Pro Gly Pro Ala Arg Arg Pro
          35                  40                  45            
 Pro Arg Arg Thr Pro Arg Pro Ala Arg Gly Arg His Pro Gly Arg Xaa
      50                  55                  60                
 Gly Gly Pro Gly Ala Ser Arg Pro Gly Gly Thr Gly Ala Ala Pro Ala
  65                  70                  75                  80
 Ala Asp Gln Thr Gly Ser Pro Ala Val Ser Thr Pro Ser Glu Phe Gly
                  85                  90                  95    
 Ala Pro Gly Gln Ala Glu Gly Pro Gln Ser Pro Ile Arg Ala Ser Ala
             100                 105                 110        
 Arg Ser His Leu Ser Cys Thr Ala Trp Leu Gly Lys Pro Ser Lys Pro
         115                 120                 125            
 Ser Ala Gln Arg Gln Pro Thr Val Gly Pro Asp Gly Asp Arg Asp Gly
     130                 135                 140                
 Ser Ser Gln Ala Pro Asn Leu Ser Arg Gly Gln Ala Trp Arg Ala Ser
 145                 150                 155                 160
 Leu Ala Ser Pro Gln Asn Thr Ser Ala Thr Gly Arg Val Thr Cys His
                 165                 170                 175    
 Gly Gln Ser Thr Trp Pro Leu Cys Arg Leu Lys Ser Asn Arg Arg Arg
             180                 185                 190        
 Lys Ser Gly Phe Ala Gly Asn Lys Ser Glu Pro Val Gly Leu Thr Arg
         195                 200                 205            
 Arg Ser Lys His Gln Pro Arg Asn Pro Gln Gly Gln Val Gly Ile
     210                 215                 220            



      <210> 2867
      <211> 148
      <212> PRT
      <213> Homo sapiens


      <400> 2867
 Met Tyr Thr Val Ser Leu Leu Leu Cys Leu Phe Phe Lys Lys Ser Asp
   1               5                  10                  15    
 Pro Asp Pro Gly Pro Phe Gln Asn Asn Leu Phe His Asn His Gly Thr
              20                  25                  30        
 Gln Ser Gln Ser Cys Met Gly Ser Lys Val Gly Asp Val Ile Pro Gly
          35                  40                  45            
 Ala Ala Arg Leu Ile Ser Glu Thr Ala Gln Arg Val His Thr Ile Gly
      50                  55                  60                
 Gln Lys Gln Lys Asn Asp Gln His Leu Arg Arg Val Gln Ala Leu Leu
  65                  70                  75                  80
 Ser Gly Arg Gln Ala Lys Gly Leu Thr Ser Gly Arg Trp Phe Leu Arg
                  85                  90                  95    
 Gln Gly Trp Leu Ile Val Val Pro Thr His Gly Glu Pro Arg Pro Arg
             100                 105                 110        
 Met Phe Phe Leu Phe Thr Asp Val Leu Leu Met Ala Lys Pro Arg Pro
         115                 120                 125            
 Thr Leu His Leu Leu Arg Ser Gly Thr Phe Ala Cys Lys Ala Leu Tyr
     130                 135                 140                
 Pro Met Ala Gln
 145            



      <210> 2868
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 2868
 Thr Gln Arg Leu Val Ile Ser Glu Pro Asp Gly Glu Ile Leu Thr Pro
   1               5                  10                  15    
 Gly Trp Asp Thr Gln Asp Arg Met Gly Val Glu Ser Arg Thr Asn Ile
              20                  25                  30        
 Gln Glu Leu Gly Asn Arg Asn Gln Arg Glu Ala Gly Gly Glu Asn Leu
          35                  40                  45            
 Pro Glu Thr Gln Ala His Met Gly Glu Thr Gln Asp Gln Leu Arg Cys
      50                  55                  60                
 Lys Ile Asp Ala Glu Thr Gln Thr Pro Glu Trp Glu Asn Gln Asp Lys
  65                  70                  75                  80
 Asn Gly Ser Glu Asp Ala Val Glu Thr Gln Thr Phe Glu Lys Lys Asp
                  85                  90                  95    
 Lys Lys Glu Ala Gly Glu Glu Asp Gly Glu Glu Ile Gln Ala Gln Gly
             100                 105                 110        
 Leu Gly Lys Gln Gly Gln Thr Gly Asp Glu Asn Gly Glu Glu Thr Gln
         115                 120                 125            
 Thr Arg Val Leu Arg Ala Leu Glu Thr Ile Pro Ala Ser Ser
     130                 135                 140        



      <210> 2869
      <211> 129
      <212> PRT
      <213> Homo sapiens


      <400> 2869
 Met Thr Pro Lys His Asp His Leu Gly His Val Leu Pro Ile Ser Leu
   1               5                  10                  15    
 Gln Leu Leu Leu Glu Leu Ser Ser Cys Leu Pro Ala Ala Ser Ala Val
              20                  25                  30        
 Trp Cys Ala Gly Cys Asn Asp Pro Trp Met Thr Gly Tyr Pro Asp Asn
          35                  40                  45            
 Met His Tyr Asn Tyr Lys Pro Met Leu His Asp Arg Gly Gly Ser Ala
      50                  55                  60                
 Val Thr Leu Ser Ala Ser Gln Ser Trp Tyr Ala Gly Cys Asn Ala Glu
  65                  70                  75                  80
 Lys Ser Glu Val Asn Ala Phe Pro Gly Thr Gln Gly Met Arg Phe Ile
                  85                  90                  95    
 Ser Ala Ala Ser Tyr Lys Asp Trp Val Gln Val Leu Gln Gln Lys Asp
             100                 105                 110        
 Val Ser Arg Asn Met Gly Thr Lys Ala Arg Ser Ala Ser Ser Leu Lys
         115                 120                 125            
 Asn
    



      <210> 2870
      <211> 1137
      <212> PRT
      <213> Homo sapiens


      <400> 2870
 Met Met Glu Gly Glu Gly Gly Val Arg Met Ser His Asp Gln Thr Gly
   1               5                  10                  15    
 Asn Lys Arg Lys His Gly Thr Ser Gly Ile Ser Val Cys Pro Asn Leu
              20                  25                  30        
 Leu Leu Leu Gln Glu Tyr Gln Pro Asp Tyr Ile Arg Ala His Ala Ser
          35                  40                  45            
 Gly Leu Asn Leu Ile Ser Ser Ser Lys Ala Leu Pro Lys Tyr Ser His
      50                  55                  60                
 Val Leu Ser Gly Leu Cys Lys Ile Cys Ser Phe Gly Pro Arg Phe Ser
  65                  70                  75                  80
 Leu His Ser Asp Thr Phe Phe Phe Ala Leu Phe Ala His Ala Asp Pro
                  85                  90                  95    
 Glu Gln Ile Arg Asn Cys Glu Thr Pro Ala Pro Pro Leu Gln Thr Glu
             100                 105                 110        
 Arg Lys Asn Glu Met Arg Ile Lys Thr His Pro Ser Ser Ser Pro Leu
         115                 120                 125            
 Tyr Asp Thr Pro Gly Arg Pro Ala Gly Ser Asp Asp Ser Ser Ser Arg
     130                 135                 140                
 Gly Arg Ala Gly Ala Leu Ser Thr Phe Leu Glu Pro Gln Arg Pro Arg
 145                 150                 155                 160
 Thr His Leu Ser Leu Ile Leu His Arg Pro Ser Pro Gly Pro Arg Leu
                 165                 170                 175    
 Ser Leu Pro Leu Phe Thr Lys Pro Ser Phe Leu Gly Ser Gly Arg Arg
             180                 185                 190        
 Glu His Ala Glu Glu Arg Ala Arg Gly Pro Arg Glu Thr Ala Ala Val
         195                 200                 205            
 Ala Ala Arg Ala Glu Gln Gly Arg Gly Gly Ser His Ser His Ser Ser
     210                 215                 220                
 Ala Leu Gly Ala Pro Arg Arg Val Ala Met Leu Pro Gly Leu Ala Leu
 225                 230                 235                 240
 Leu Leu Leu Ala Ala Trp Thr Ala Arg Ala Leu Glu Ser Leu Glu Asn
                 245                 250                 255    
 Arg Ser Ala Ala Gly Gly Cys Arg Lys Glu Met Asn Lys Gly Asn Asp
             260                 265                 270        
 Asn Gly Ala Leu Ala Ile Gly Gly Asn Met Val Ile Ile Trp Val Asp
         275                 280                 285            
 Asp Phe Gly Trp Tyr Val Asp Arg Asp Thr Leu Glu Gln Gly Ser Pro
     290                 295                 300                
 Thr Pro Ser His Gly Gln Val Leu Val His Gly Leu Leu Gly Thr Gly
 305                 310                 315                 320
 Pro His Ser Arg Ser Thr Leu Asn Ile Lys Glu Gln Leu Pro Arg Ser
                 325                 330                 335    
 Lys Ile Ser Ser Ile Gly Ala Cys Asn Ile Ile Phe Gln Val Asp Ile
             340                 345                 350        
 Asn Ala Ile Phe Gly Ile Leu Met Val Pro Thr Asp Gly Asn Ala Gly
         355                 360                 365            
 Leu Leu Ala Glu Pro Gln Ile Ala Met Phe Cys Gly Arg Leu Asn Met
     370                 375                 380                
 His Met Asn Val Gln Asn Gly Lys Trp Asp Ser Asp Pro Ser Gly Thr
 385                 390                 395                 400
 Lys Thr Cys Ile Asp Thr Lys Glu Gly Ile Leu Gln Tyr Cys Gln Glu
                 405                 410                 415    
 Val Tyr Pro Glu Leu Gln Ile Thr Asn Val Val Glu Ala Asn Gln Pro
             420                 425                 430        
 Val Thr Ile Gln Asn Trp Cys Lys Arg Gly Arg Lys Gln Cys Lys Thr
         435                 440                 445            
 His Pro His Phe Val Ile Pro Tyr Arg Cys Leu Val Gly Glu Phe Val
     450                 455                 460                
 Ser Asp Ala Leu Leu Val Pro Asp Lys Cys Lys Phe Leu His Gln Glu
 465                 470                 475                 480
 Arg Met Asp Val Cys Glu Thr His Leu His Trp His Thr Val Ala Lys
                 485                 490                 495    
 Glu Thr Cys Ser Glu Lys Ser Thr Asn Leu His Asp Tyr Gly Met Leu
             500                 505                 510        
 Leu Pro Cys Gly Ile Asp Lys Phe Arg Gly Val Glu Phe Val Cys Cys
         515                 520                 525            
 Pro Leu Ala Glu Glu Ser Asp Asn Val Asp Ser Ala Asp Ala Glu Glu
     530                 535                 540                
 Asp Asp Ser Asp Val Trp Trp Gly Gly Ala Asp Thr Asp Tyr Ala Asp
 545                 550                 555                 560
 Gly Arg Thr Ser Ala Ile Phe Gly Tyr Asp His Asp Cys Lys Val His
                 565                 570                 575    
 Asp Ala Phe Ala Leu Ser Ser Val Leu Val Asp Arg Gln Glu Trp Gly
             580                 585                 590        
 Ser Thr Tyr Glu Ser Gly Ala Gly Gln Gly Ile Ala Ala Phe Trp Gly
         595                 600                 605            
 Ala Cys Trp Lys Glu Glu Gln Ser Leu Leu Phe Leu Leu Pro Asp Met
     610                 615                 620                
 Asp Trp Leu Cys Leu His Ser Asn Ile Asn Phe Asn Tyr Ile Ser Gln
 625                 630                 635                 640
 Asn Ser His Met Leu Trp Arg Asp Pro Gly Glu Ile Asp Ser Lys Lys
                 645                 650                 655    
 Leu Ser Ala Leu Ser Ser Leu Pro Gly Ile Val Leu Ala Leu Gly Lys
             660                 665                 670        
 Ala Gln Arg Ile Leu Leu Ile Glu Leu Leu Gly Val Gly Leu Glu Ser
         675                 680                 685            
 Glu Asp Lys Val Val Glu Val Ala Glu Glu Glu Glu Val Ala Glu Val
     690                 695                 700                
 Glu Glu Glu Glu Ala Asp Asp Asp Glu Asp Asp Glu Asp Gly Asp Glu
 705                 710                 715                 720
 Val Glu Glu Glu Ala Glu Glu Pro Tyr Glu Glu Ala Thr Glu Arg Thr
                 725                 730                 735    
 Thr Ser Ile Ala Thr Thr Thr Thr Thr Thr Thr Glu Ser Val Glu Glu
             740                 745                 750        
 Val Val Arg Glu Val Cys Ser Glu Gln Ala Glu Thr Gly Pro Cys Arg
         755                 760                 765            
 Ala Met Ile Ser Arg Trp Tyr Phe Asp Val Thr Glu Gly Lys Cys Ala
     770                 775                 780                
 Pro Phe Phe Tyr Gly Gly Cys Gly Gly Asn Arg Asn Asn Phe Asp Thr
 785                 790                 795                 800
 Glu Glu Tyr Cys Met Ala Val Cys Gly Ser Ala Thr Asn Cys Thr Phe
                 805                 810                 815    
 Asp Leu Lys Lys Ser Trp Ser Ser Gly Gly Gln Ile Gln Met Ala Asp
             820                 825                 830        
 Ser Ile Gln Arg Lys Gly Ala Glu Leu Glu Ala Ile Cys Gln Lys Arg
         835                 840                 845            
 Phe Ser Gln Arg Lys His Arg Tyr Gly Lys Cys Phe Val Gly Val Leu
     850                 855                 860                
 Ala Pro Val Met Glu Glu His Phe Val Ile Gly Thr Leu Gly Ala Ala
 865                 870                 875                 880
 Ser Pro Phe Met Asn Lys Leu Lys Ala Asn Leu Cys Tyr Phe Thr Pro
                 885                 890                 895    
 Glu Asn Arg Ala Leu Ala Val Pro Thr Thr Ala Ala Ser Thr Pro Asp
             900                 905                 910        
 Ala Val Asp Lys Tyr Leu Glu Thr Pro Gly Asp Glu Asn Glu His Ala
         915                 920                 925            
 His Phe Gln Lys Ala Lys Glu Arg Leu Glu Ala Lys His Arg Glu Arg
     930                 935                 940                
 Met Ser Gln Val Met Arg Glu Trp Glu Glu Ala Glu Arg Gln Ala Lys
 945                 950                 955                 960
 Asn Leu Pro Lys Ala Asp Lys Lys Ala Val Ile Gln His Phe Gln Glu
                 965                 970                 975    
 Lys Val Glu Ser Leu Glu Gln Glu Ala Ala Asn Glu Arg Gln Gln Leu
             980                 985                 990        
 Val Glu Thr His Met Ala Arg Val Glu Ala Met Leu Asn Asp Arg Arg
         995                1000                1005            
 Arg Leu Ala Leu Glu Asn Tyr Ile Thr Ala Leu Gln Ala Val Pro Pro
    1010                1015                1020                
 Arg Val Gly Leu Ala Ala Ala Glu Phe Thr Leu Gln Val Thr Ala Gln
1025                1030                1035                1040
 Thr Pro Arg His Val Phe Asn Met Leu Lys Lys Tyr Val Arg Ala Glu
                1045                1050                1055    
 Gln Lys Asp Arg Gln His Thr Leu Lys His Phe Glu His Val Arg Met
            1060                1065                1070        
 Val Asp Pro Lys Lys Ala Ala Gln Ile Arg Ser Gln Val Met Thr His
        1075                1080                1085            
 Leu Arg Val Ile Tyr Glu Arg Met Asn Gln Ser Leu Ser Leu Leu Tyr
    1090                1095                1100                
 Asn Val Pro Ala Val Ala Glu Glu Ile Gln Asp Glu Val Ala Phe Lys
1105                1110                1115                1120
 Ile Asn Lys Asn Met Asn Tyr Tyr Lys Pro Asp Ala Gly Lys Ile Ser
                1125                1130                1135    
 Gly
    



      <210> 2871
      <211> 121
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(121)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2871
 Gly Lys Met Pro Pro His Leu Ala Met Gly Cys Pro Pro Arg Leu Asn
   1               5                  10                  15    
 Pro Trp Glu Gln Pro Glu Leu Gly Ala Arg Gly Arg Gly Asp Gly Cys
              20                  25                  30        
 Pro Cys Pro Ala Glu His Gly Trp Ala Leu Asp Val Arg Tyr Ser Xaa
          35                  40                  45            
 Leu Pro Leu Pro Gln Ser Leu Ala Ser Ser Leu Ala Ile Pro Pro Gln
      50                  55                  60                
 Val Phe Cys Ser Phe Thr Leu Ser Ser Lys Ser Pro Arg Pro Ala Ala
  65                  70                  75                  80
 Arg Gln Glu Thr Pro Ala Gly Ala Pro Pro Ala Gly Pro Ser Phe Ala
                  85                  90                  95    
 Gly Arg Arg Arg Thr Ile Pro Gly Ser Gly Ala Pro Arg Arg Ser Pro
             100                 105                 110        
 Gly Gly Arg Arg Gln Glu Gln Leu Arg
         115                 120    



      <210> 2872
      <211> 89
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(89)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2872
 Cys Cys Leu Ala Ala His Ser Gly Pro Pro Ala Gln Gly Gln Arg Arg
   1               5                  10                  15    
 Gly Pro Gly Xaa Leu Cys Cys Ser Ala Gly Ser Gly Gly Asn Leu Xaa
              20                  25                  30        
 Ser Xaa Ala Gly Gly Pro Gly Xaa Gly Arg Ser Gly Gln Pro Val Cys
          35                  40                  45            
 Pro Pro Trp Pro Gly Pro Gly Ala Pro Gly His Arg Pro Ala Leu Pro
      50                  55                  60                
 Gly Ser Gly Gly Ser Ser Ala Val Gly Arg Ser Ala Val Pro Gly Ala
  65                  70                  75                  80
 Val Arg Ser Pro Ser His Ala Gly Trp
                  85                



      <210> 2873
      <211> 161
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(161)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2873
 Ala Leu Leu Glu Ser Leu Ser Ser Gly Glu Ala Gln Ala Trp Gly Ala
   1               5                  10                  15    
 Pro Arg Leu Val Ala Gly Ile Arg Leu Ile Glu His Lys Cys Val Leu
              20                  25                  30        
 Gly Gly Gly Thr Ala Gly Ala Trp Gly Xaa Lys Asp Gln Val Thr Ile
          35                  40                  45            
 Gln Pro Ala Gly His Ala Pro Gly Leu Ser Gly Thr Glu Ala Thr Val
      50                  55                  60                
 Thr Pro Asp Asp Ser Val Ser Asp Pro Thr Thr Trp Pro Ser Gln Glu
  65                  70                  75                  80
 Val Ser Met Cys His Pro Leu Pro Gly Ser His Pro Ser His Leu Leu
                  85                  90                  95    
 Lys Glu Gly Met Thr Ser Val Arg Pro Arg Ala Leu Gln Gln Gly Pro
             100                 105                 110        
 Pro Trp Gln Leu Gln Thr Lys Asp Ser Ala Pro Pro Pro Xaa Thr Pro
         115                 120                 125            
 Ala Ser Phe Ser Pro Phe Phe Pro Leu Ser Pro Leu Pro Val Ser Pro
     130                 135                 140                
 Ser Leu Ser His Thr His Ser Phe Arg Val Gln Gly Ala Lys Arg Phe
 145                 150                 155                 160
 Ala
    



      <210> 2874
      <211> 336
      <212> PRT
      <213> Homo sapiens


      <400> 2874
 Ala Arg Val Arg Trp Arg Pro Pro Arg Trp Pro Pro Arg Ala Ser Cys
   1               5                  10                  15    
 Pro Gly Pro Ala Leu Arg Leu Cys Arg Gly Gly Ser Met Gly Gly Pro
              20                  25                  30        
 Arg Gly Ala Gly Trp Val Ala Ala Gly Leu Leu Leu Gly Ala Gly Ala
          35                  40                  45            
 Cys Tyr Cys Ile Tyr Arg Leu Thr Arg Gly Arg Arg Arg Gly Asp Arg
      50                  55                  60                
 Glu Leu Gly Ile Arg Ser Ser Lys Ser Ala Glu Asp Leu Thr Asp Gly
  65                  70                  75                  80
 Ser Tyr Asp Asp Val Leu Asn Ala Glu Gln Leu Gln Lys Leu Leu Tyr
                  85                  90                  95    
 Leu Leu Glu Ser Thr Glu Asp Pro Val Ile Ile Glu Arg Ala Leu Ile
             100                 105                 110        
 Thr Leu Gly Asn Asn Ala Ala Phe Ser Val Asn Gln Ala Ile Ile Arg
         115                 120                 125            
 Glu Leu Gly Gly Ile Pro Ile Val Ala Asn Lys Ile Asn His Ser Asn
     130                 135                 140                
 Gln Ser Ile Lys Glu Lys Ala Leu Asn Ala Leu Asn Asn Leu Ser Val
 145                 150                 155                 160
 Asn Val Glu Asn Gln Ile Lys Ile Lys Ile Tyr Ile Ser Gln Val Cys
                 165                 170                 175    
 Glu Asp Val Phe Ser Gly Pro Leu Asn Ser Ala Val Gln Leu Ala Gly
             180                 185                 190        
 Leu Thr Leu Leu Thr Asn Met Thr Val Thr Asn Asp His Gln His Met
         195                 200                 205            
 Leu His Ser Tyr Ile Thr Asp Leu Phe Gln Val Leu Leu Thr Gly Asn
     210                 215                 220                
 Gly Asn Thr Lys Val Gln Val Leu Lys Leu Leu Leu Asn Leu Ser Glu
 225                 230                 235                 240
 Asn Pro Ala Met Thr Glu Gly Leu Leu Arg Ala Gln Val Asp Ser Ser
                 245                 250                 255    
 Phe Leu Ser Leu Tyr Asp Ser His Val Ala Lys Glu Ile Leu Leu Arg
             260                 265                 270        
 Val Leu Thr Leu Phe Gln Asn Ile Lys Asn Cys Leu Lys Ile Glu Gly
         275                 280                 285            
 His Leu Ala Val Gln Pro Thr Phe Thr Glu Gly Ser Leu Phe Phe Leu
     290                 295                 300                
 Leu His Gly Glu Glu Cys Ala Gln Lys Ile Arg Ala Leu Val Asp His
 305                 310                 315                 320
 His Asp Ala Glu Val Lys Glu Lys Val Val Thr Ile Ile Pro Lys Ile
                 325                 330                 335    





      <210> 2875
      <211> 176
      <212> PRT
      <213> Homo sapiens


      <400> 2875
 Met Ala Arg Asn Glu Cys Val Asp Gly Gln Pro Gly His Leu Val Asp
   1               5                  10                  15    
 Phe Thr Cys Leu Val Thr Tyr Arg Val Ser Gly Glu Ser Arg Ala Pro
              20                  25                  30        
 His Pro Met Ala Glu Leu Phe Leu Val Ile Tyr His Met Glu Glu Lys
          35                  40                  45            
 Leu Glu Thr His Ile Pro Arg Lys Gln Glu Arg Val Glu Glu Lys Gly
      50                  55                  60                
 Pro Cys Ile Cys Lys Ala Leu Ser Pro Asn Ser Val Asn Gln Arg Asp
  65                  70                  75                  80
 Ala Arg Glu Lys Glu Met Leu Gln Gln Leu Gln Asn Arg Asp Thr Lys
                  85                  90                  95    
 Gln Val Leu Pro Ser Lys Ala Ser Ala His Thr Pro Leu Asp Lys Ala
             100                 105                 110        
 His His Thr Ala Lys Pro Asp Gly Ser Gly Gly Glu Lys Asp Phe Leu
         115                 120                 125            
 His Thr Arg Thr Thr Pro Pro Pro Leu Leu Gln Gly Arg Ala Gly Asn
     130                 135                 140                
 Ile Phe Asn Asn Lys Thr Val Tyr Arg Ser Asn Thr Ile Ile Thr Ile
 145                 150                 155                 160
 Gly Arg Trp Val Leu Arg Ala Ile Glu Leu Arg Pro Lys Asp Asn Asn
                 165                 170                 175    





      <210> 2876
      <211> 428
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(428)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2876
 Glu Pro Val Phe Glu Gln Ala Ile Asp Gln Arg Ser Ser Thr Asp Thr
   1               5                  10                  15    
 Ser Leu Ser Thr Pro Ala Ala Pro Met Val Asp Ser Leu Ile Ala Arg
              20                  25                  30        
 Val Gly Val Met Ala Arg Gly Asn Ala Ile Thr Leu Pro Val Cys Gly
          35                  40                  45            
 Arg Asp Val Lys Phe Thr Leu Glu Val Leu Arg Gly Asp Ser Val Glu
      50                  55                  60                
 Lys Thr Ser Arg Val Trp Ser Gly Asn Glu Arg Asp Gln Glu Leu Leu
  65                  70                  75                  80
 Thr Glu Asp Ala Leu Asp Asp Leu Ile Pro Ser Phe Leu Leu Thr Gly
                  85                  90                  95    
 Gln Gln Thr Pro Ala Phe Gly Arg Arg Val Ser Gly Val Ile Glu Ile
             100                 105                 110        
 Ala Asp Gly Ser Arg Arg Arg Lys Ala Ala Ala Leu Thr Glu Ser Asp
         115                 120                 125            
 Tyr Arg Val Leu Val Gly Glu Leu Asp Asp Glu Gln Met Ala Ala Leu
     130                 135                 140                
 Ser Arg Leu Gly Asn Asp Tyr Arg Pro Thr Ser Ala Tyr Glu Arg Gly
 145                 150                 155                 160
 Gln Arg Tyr Ala Ser Arg Leu Gln Asn Glu Phe Ala Gly Asn Ile Ser
                 165                 170                 175    
 Ala Leu Ala Asp Ala Glu Asn Ile Ser Gln Xaa Ile Cys Trp Lys Tyr
             180                 185                 190        
 Phe Cys Ala Gly Xaa Cys Gly Lys Tyr Phe Arg Lys Ile Ile Thr Arg
         195                 200                 205            
 Cys Ile Asn Thr Ala Lys Leu Pro Lys Ser Val Val Ala Leu Phe Ser
     210                 215                 220                
 His Pro Gly Glu Leu Ser Ala Arg Ser Gly Asp Ala Leu Gln Lys Ala
 225                 230                 235                 240
 Phe Thr Asp Lys Glu Glu Leu Leu Lys Gln Gln Ala Ser Asn Leu His
                 245                 250                 255    
 Glu Gln Lys Lys Ala Gly Val Ile Ser Pro Pro Glu Glu Val Ile Thr
             260                 265                 270        
 Leu Leu Thr Ser Glu Ile Lys Thr Ser Ser Ala Ser Arg Thr Ser Leu
         275                 280                 285            
 Ser Ser Arg His Gln Phe Ala Pro Gly Ala Thr Val Leu Tyr Lys Gly
     290                 295                 300                
 Asp Lys Met Phe Ile Thr Val Lys Ile Ala Lys Arg Ser Gln Ala Pro
 305                 310                 315                 320
 Cys Met Lys Ser Asn Asn Ala Leu Ile Val Ile Leu Gly Thr Val Thr
                 325                 330                 335    
 Leu Asp Ala Val Gly Ile Gly Leu Val Met Pro Val Leu Pro Gly Leu
             340                 345                 350        
 Leu Arg Asp Ile Val His Ser Asp Ser Ile Ala Ser His Tyr Gly Val
         355                 360                 365            
 Leu Leu Ala Leu Tyr Ala Leu Met Gln Phe Leu Cys Ala Pro Val Leu
     370                 375                 380                
 Gly Ala Leu Ser Asp Arg Phe Gly Arg Arg Pro Val Leu Leu Ala Ser
 385                 390                 395                 400
 Leu Leu Gly Ala Thr Ile Asp Tyr Ala Ile Met Ala Thr Thr Pro Val
                 405                 410                 415    
 Leu Trp Ile Tyr Pro Leu Val Asn Ser Pro Ser Cys
             420                 425            



      <210> 2877
      <211> 855
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(855)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2877
 Xaa Ala Leu Met Ile Glu Ile Asp Gly Gly Glu Ser Trp Ser Phe Met
   1               5                  10                  15    
 Asp Asp Asn Gln Asn Lys Thr His Asp Lys Lys Glu Lys Lys Met Val
              20                  25                  30        
 Val Gln Lys Pro His Gly Thr Met Glu Tyr Thr Ala Gly Asn Gln Asp
          35                  40                  45            
 Thr Leu Asn Ser Ile Ala Leu Lys Phe Asn Ile Thr Pro Asn Lys Leu
      50                  55                  60                
 Val Glu Leu Asn Lys Leu Phe Thr His Thr Ile Val Pro Gly Gln Val
  65                  70                  75                  80
 Leu Phe Val Pro Asp Ala Asn Ser Pro Ser Ser Thr Leu Arg Leu Ser
                  85                  90                  95    
 Ser Ser Ser Pro Gly Ala Thr Val Ser Pro Ser Ser Ser Asp Ala Glu
             100                 105                 110        
 Tyr Asp Lys Leu Pro Asp Ala Asp Leu Ala Arg Lys Ala Leu Lys Pro
         115                 120                 125            
 Ile Glu Arg Val Leu Ser Ser Thr Ser Glu Glu Asp Glu Pro Gly Val
     130                 135                 140                
 Val Lys Phe Leu Lys Met Asn Cys Arg Tyr Phe Thr Asp Gly Lys Gly
 145                 150                 155                 160
 Val Val Gly Gly Val Met Ile Val Thr Pro Asn Asn Ile Met Phe Asp
                 165                 170                 175    
 Pro His Lys Ser Asp Pro Leu Val Ile Glu Asn Gly Cys Glu Glu Tyr
             180                 185                 190        
 Gly Leu Ile Cys Pro Met Glu Glu Val Val Ser Ile Ala Leu Tyr Asn
         195                 200                 205            
 Asp Ile Ser His Met Lys Ile Lys Asp Ala Leu Pro Ser Pro Gly Glu
     210                 215                 220                
 Trp Glu Asp Leu Ala Ser Glu Lys Asp Ile Asn Pro Phe Ser Lys Phe
 225                 230                 235                 240
 Lys Ser Ile Asn Lys Glu Lys Arg Gln Gln Asn Gly Glu Lys Ile Met
                 245                 250                 255    
 Thr Ser Asp Ser Arg Pro Ile Val Pro Leu Glu Lys Ser Thr Gly His
             260                 265                 270        
 Thr Pro Thr Lys Pro Ser Gly Ser Ser Val Ser Glu Lys Leu Lys Lys
         275                 280                 285            
 Leu Asp Ser Ser Arg Glu Thr Ser His Gly Ser Pro Thr Val Thr Lys
     290                 295                 300                
 Leu Ser Lys Glu Pro Ser Asp Thr Ser Ser Ala Phe Glu Ser Thr Ala
 305                 310                 315                 320
 Lys Glu Asn Phe Leu Gly Glu Asp Asp Asp Phe Val Asp Leu Glu Glu
                 325                 330                 335    
 Leu Ser Ser Gln Thr Gly Gly Gly Met His Lys Lys Asp Thr Leu Lys
             340                 345                 350        
 Glu Cys Leu Ser Leu Asp Pro Glu Glu Arg Lys Lys Ala Glu Ser Gln
         355                 360                 365            
 Ile Asn Asn Ser Ala Val Glu Met Gln Val Gln Ser Ala Leu Ala Phe
     370                 375                 380                
 Leu Gly Thr Glu Asn Asp Val Glu Leu Lys Gly Ala Leu Asp Leu Glu
 385                 390                 395                 400
 Thr Cys Glu Lys Gln Asp Ile Met Pro Glu Val Asp Lys Gln Ser Gly
                 405                 410                 415    
 Ser Pro Glu Ser Arg Val Glu Asn Thr Leu Asn Ile His Glu Asp Leu
             420                 425                 430        
 Asp Lys Val Lys Leu Ile Glu Tyr Tyr Leu Thr Lys Asn Lys Glu Gly
         435                 440                 445            
 Pro Gln Val Ser Glu Asn Leu Gln Lys Thr Glu Leu Ser Asp Gly Lys
     450                 455                 460                
 Ser Ile Glu Pro Gly Gly Ile Asp Ile Thr Leu Ser Ser Ser Leu Ser
 465                 470                 475                 480
 Gln Ala Gly Asp Pro Ile Thr Glu Gly Asn Lys Glu Pro Asp Lys Thr
                 485                 490                 495    
 Trp Val Lys Lys Gly Glu Pro Leu Pro Val Lys Leu Asn Ser Ser Thr
             500                 505                 510        
 Glu Ala Asn Val Ile Lys Glu Ala Leu Asp Ser Ser Leu Glu Ser Thr
         515                 520                 525            
 Leu Asp Asn Ser Cys Gln Gly Ala Gln Met Asp Asn Lys Ser Glu Val
     530                 535                 540                
 Gln Leu Trp Leu Leu Lys Arg Ile Gln Val Pro Ile Glu Asp Ile Leu
 545                 550                 555                 560
 Pro Ser Lys Glu Glu Lys Ser Lys Thr Pro Pro Met Phe Leu Cys Ile
                 565                 570                 575    
 Lys Val Gly Lys Pro Met Arg Lys Ser Phe Ala Thr His Thr Ala Ala
             580                 585                 590        
 Met Val Gln Gln Tyr Gly Lys Arg Arg Lys Gln Pro Glu Tyr Trp Phe
         595                 600                 605            
 Ala Val Pro Arg Glu Arg Val Asp His Leu Tyr Thr Phe Phe Val Gln
     610                 615                 620                
 Trp Ser Pro Asp Val Tyr Gly Lys Asp Ala Lys Glu Gln Gly Phe Val
 625                 630                 635                 640
 Val Val Glu Lys Glu Glu Leu Asn Met Ile Asp Asn Phe Phe Ser Glu
                 645                 650                 655    
 Pro Thr Thr Lys Ser Trp Glu Ile Ile Thr Val Glu Glu Ala Lys Arg
             660                 665                 670        
 Arg Lys Ser Thr Cys Ser Tyr Tyr Glu Asp Glu Asp Glu Glu Val Leu
         675                 680                 685            
 Pro Val Leu Arg Pro His Ser Ala Leu Leu Glu Asn Met His Ile Glu
     690                 695                 700                
 Gln Leu Ala Arg Arg Leu Pro Cys Lys Gly Tyr Pro Trp Arg Leu Ala
 705                 710                 715                 720
 Tyr Ser Thr Leu Glu His Gly Thr Ser Leu Lys Thr Leu Tyr Arg Lys
                 725                 730                 735    
 Ser Ala Ser Leu Asp Ser Pro Val Leu Leu Val Ile Lys Asp Met Asp
             740                 745                 750        
 Asn Gln Ile Phe Gly Ala Tyr Ala Thr His Pro Phe Lys Phe Ser Asp
         755                 760                 765            
 His Tyr Tyr Gly Thr Gly Glu Thr Phe Leu Tyr Thr Phe Ser Pro His
     770                 775                 780                
 Phe Lys Val Phe Lys Trp Ser Gly Glu Asn Ser Tyr Phe Ile Asn Gly
 785                 790                 795                 800
 Asp Ile Ser Ser Leu Glu Leu Gly Gly Gly Gly Gly Arg Phe Gly Leu
                 805                 810                 815    
 Trp Leu Asp Ala Asp Leu Tyr His Gly Arg Ser Asn Ser Cys Ser Thr
             820                 825                 830        
 Phe Asn Asn Asp Ile Leu Ser Lys Lys Glu Asp Phe Ile Val Gln Asp
         835                 840                 845            
 Leu Glu Val Trp Ala Phe Asp
     850                 855



      <210> 2878
      <211> 679
      <212> PRT
      <213> Homo sapiens


      <400> 2878
 Ser Val Lys Asn Tyr Thr Lys Cys His Val Arg Asn Glu Gln Ile Cys
   1               5                  10                  15    
 Asn Lys Leu Thr Ser Cys Lys Ser Cys Ser Leu Asn Leu Asn Cys Gln
              20                  25                  30        
 Trp Asp Gln Arg Gln Gln Glu Cys Gln Ala Leu Pro Ala His Leu Cys
          35                  40                  45            
 Gly Glu Gly Trp Ser His Ile Gly Asp Ala Cys Leu Arg Val Asn Ser
      50                  55                  60                
 Ser Arg Glu Asn Tyr Asp Asn Ala Lys Leu Tyr Cys Tyr Asn Leu Ser
  65                  70                  75                  80
 Gly Asn Leu Ala Ser Leu Thr Thr Ser Lys Glu Val Glu Phe Val Leu
                  85                  90                  95    
 Asp Glu Ile Gln Lys Tyr Thr Gln Gln Lys Val Ser Pro Trp Val Gly
             100                 105                 110        
 Leu Arg Lys Ile Asn Ile Ser Tyr Trp Gly Trp Glu Asp Met Ser Pro
         115                 120                 125            
 Phe Thr Asn Thr Thr Leu Gln Trp Leu Pro Gly Glu Pro Asn Asp Ser
     130                 135                 140                
 Gly Phe Cys Ala Tyr Leu Glu Arg Ala Ala Val Ala Gly Leu Lys Ala
 145                 150                 155                 160
 Asn Pro Cys Thr Ser Met Ala Asn Gly Leu Val Cys Glu Lys Pro Val
                 165                 170                 175    
 Val Ser Pro Asn Gln Asn Ala Arg Pro Cys Lys Lys Pro Cys Ser Leu
             180                 185                 190        
 Arg Thr Ser Cys Ser Asn Cys Thr Ser Asn Gly Met Glu Cys Met Trp
         195                 200                 205            
 Cys Ser Ser Thr Lys Arg Cys Val Asp Ser Asn Ala Tyr Ile Ile Ser
     210                 215                 220                
 Phe Pro Tyr Gly Gln Cys Leu Glu Trp Gln Thr Ala Thr Cys Ser Pro
 225                 230                 235                 240
 Gln Asn Cys Ser Gly Leu Arg Thr Cys Gly Gln Cys Leu Glu Gln Pro
                 245                 250                 255    
 Gly Cys Gly Trp Cys Asn Asp Pro Ser Asn Thr Gly Arg Gly His Cys
             260                 265                 270        
 Ile Glu Gly Ser Ser Arg Gly Pro Met Lys Leu Ile Gly Met His His
         275                 280                 285            
 Asn Glu Met Val Leu Asp Thr Asn Leu Cys Pro Lys Glu Lys Asn Tyr
     290                 295                 300                
 Glu Trp Ser Phe Ile Gln Cys Pro Ala Cys Gln Cys Asn Gly His Ser
 305                 310                 315                 320
 Thr Cys Ile Asn Asn Asn Val Cys Glu Gln Cys Lys Asn Leu Thr Thr
                 325                 330                 335    
 Gly Lys Gln Cys Gln Asp Cys Met Pro Gly Tyr Tyr Gly Asp Pro Thr
             340                 345                 350        
 Asn Gly Gly Gln Cys Thr Ala Cys Thr Cys Ser Gly His Ala Asn Ile
         355                 360                 365            
 Cys His Leu His Thr Gly Lys Cys Phe Cys Thr Thr Lys Gly Ile Lys
     370                 375                 380                
 Gly Asp Gln Cys Gln Leu Cys Asp Ser Glu Asn Arg Tyr Val Gly Asn
 385                 390                 395                 400
 Pro Leu Arg Gly Thr Cys Tyr Tyr Ser Leu Leu Ile Asp Tyr Gln Phe
                 405                 410                 415    
 Thr Phe Ser Leu Leu Gln Glu Asp Asp Arg His His Thr Ala Ile Asn
             420                 425                 430        
 Phe Ile Ala Asn Pro Glu Gln Ser Asn Lys Asn Leu Asp Ile Ser Ile
         435                 440                 445            
 Asn Ala Ser Asn Asn Phe Asn Leu Asn Ile Thr Trp Ser Val Gly Ser
     450                 455                 460                
 Thr Ala Gly Thr Ile Ser Gly Glu Glu Thr Ser Ile Val Ser Lys Asn
 465                 470                 475                 480
 Asn Ile Lys Glu Tyr Arg Asp Ser Phe Ser Tyr Glu Lys Phe Asn Phe
                 485                 490                 495    
 Arg Ser Asn Pro Asn Ile Thr Phe Tyr Val Tyr Val Ser Asn Phe Ser
             500                 505                 510        
 Trp Pro Ile Lys Ile Gln Ile Ala Phe Ser Gln His Asn Thr Ile Met
         515                 520                 525            
 Asp Leu Val Gln Phe Phe Val Thr Phe Phe Ser Cys Phe Leu Ser Leu
     530                 535                 540                
 Leu Leu Val Ala Ala Val Val Trp Lys Ile Lys Gln Thr Cys Trp Ala
 545                 550                 555                 560
 Ser Arg Arg Arg Glu Gln Leu Leu Arg Glu Arg Gln Gln Met Ala Ser
                 565                 570                 575    
 Arg Pro Phe Ala Ser Val Asp Val Ala Leu Glu Val Gly Ala Glu Gln
             580                 585                 590        
 Thr Glu Phe Leu Arg Gly Pro Leu Glu Gly Ala Pro Lys Pro Ile Ala
         595                 600                 605            
 Ile Glu Pro Cys Ala Gly Asn Arg Ala Ala Val Leu Thr Val Phe Leu
     610                 615                 620                
 Cys Leu Pro Arg Gly Ser Ser Gly Ala Pro Pro Pro Gly Gln Ser Gly
 625                 630                 635                 640
 Leu Ala Ile Ala Ser Ala Leu Ile Asp Ile Ser Gln Gln Lys Ala Ser
                 645                 650                 655    
 Asp Ser Lys Asp Lys Thr Ser Gly Val Arg Asn Arg Lys His Leu Ser
             660                 665                 670        
 Thr Arg Gln Gly Thr Cys Val
         675                



      <210> 2879
      <211> 377
      <212> PRT
      <213> Homo sapiens


      <400> 2879
 Met Lys Val Thr Phe Ala Asn Lys Pro Glu Gly Gly Gly Arg Leu Ala
   1               5                  10                  15    
 Lys Gln Arg Pro Pro Gly Arg Gly Ala Arg Pro Arg Pro Lys His Glu
              20                  25                  30        
 Gly Gly Gln Ser Val Leu Gly Thr Arg Arg Pro Ala Leu Leu Gln Val
          35                  40                  45            
 Ser Cys Thr Asp Val Ser Leu Ser Glu Gln Asp Lys Asp Gly Ala Thr
      50                  55                  60                
 Ala Thr His Phe Ala Ala Ser Arg Gly His Ser Lys Val Leu Ser Trp
  65                  70                  75                  80
 Leu Leu Leu His Gly Gly Glu Ile Ser Ala Asp Leu Trp Gly Gly Thr
                  85                  90                  95    
 Ala Leu Tyr Asp Ala Ala Glu Asn Gly Glu Leu Gly Cys Cys Gln Ile
             100                 105                 110        
 Leu Val Val Asn Gly Ala Glu Leu Glu Val Arg Asp Arg Asp Gly Tyr
         115                 120                 125            
 Ala Ala Ala Asp Leu Ser Asp Phe Asn Gly His Ser His Cys Thr His
     130                 135                 140                
 Cys Leu Arg Thr Val Glu Asn Leu His Arg Gly Met Val Leu Ala Leu
 145                 150                 155                 160
 Gly Ala Ala Glu His Ser Lys Ala Gln Arg Pro Glu Ala Ala Gly Gly
                 165                 170                 175    
 Pro Glu Gly Glu Leu Pro Pro Glu Lys Glu Ser Leu Glu Glu Asn Glu
             180                 185                 190        
 Trp Pro Ser Arg Gly Gln Gly Leu Val Pro Ser Ala Pro Thr Ala Val
         195                 200                 205            
 Ala Gln Ser Met Glu His Cys Val Leu Ser Arg Asp Pro Ser Val Glu
     210                 215                 220                
 Leu Glu Ala Lys Gln Pro Asp Ser Gly Met Ser Ser Pro Asn Thr Thr
 225                 230                 235                 240
 Val Ser Val Gln Pro Leu Asn Phe Asp Leu Ser Ser Pro Thr Ser Thr
                 245                 250                 255    
 Leu Ser Asn Tyr Asp Ser Cys Ser Ser Ser His Ser Ser Ile Lys Gly
             260                 265                 270        
 Gln His Pro Pro Arg Ala Pro Asn Pro Gln Ile Leu Gln Tyr Lys Lys
         275                 280                 285            
 Arg Phe Ser Glu Leu Glu Gln Leu Leu Glu Arg Ser Gly Glu Leu Glu
     290                 295                 300                
 Gln Gln Gln Leu Arg Asp Ala Glu His Ser Gln Asp Leu Glu Ser Ala
 305                 310                 315                 320
 Leu Ile Trp Leu Glu Glu Glu Gln Gln Gly Gly Pro Gly Leu Ala Ala
                 325                 330                 335    
 Trp Pro Pro Gly Arg Ala Pro Thr Asp Pro Leu Cys Pro Ile Gln Glu
             340                 345                 350        
 Cys Gln Pro Gly Pro Gly Glu Cys His Ala Leu Arg Thr Ala Gly Pro
         355                 360                 365            
 Gly Arg Phe Gly Gln Pro Gly Ser Glu
     370                 375        



      <210> 2880
      <211> 138
      <212> PRT
      <213> Homo sapiens


      <400> 2880
 Phe Arg Thr Asp Ala Arg Val Ala Ile Thr Ile Tyr Tyr Gln Ala Thr
   1               5                  10                  15    
 Glu Glu Phe Gln Asn Gly Ile Ala Ser Tyr Ile Pro Lys Asp Asn Ser
              20                  25                  30        
 Leu Gln Ser Glu Thr Val Gln Tyr Lys Arg Gly Val Cys Gln Gln Phe
          35                  40                  45            
 Cys Leu Pro Ser His Thr Val Asp Pro Ser Glu Trp Ala Glu Glu Glu
      50                  55                  60                
 Leu Gly Phe Asp Leu Asp Arg Glu Val Tyr Pro Leu Val Val His Ala
  65                  70                  75                  80
 Val Val Asp Glu Gly Asp Glu Tyr Phe Gly His Cys His Val Leu Leu
                  85                  90                  95    
 Gly Thr Phe Glu Lys His Thr Asp Gly Thr Phe Cys Val Lys Pro Leu
             100                 105                 110        
 Lys Gln Lys Gln Val Val Asp Gly Val Ser Tyr Leu Leu Gln Glu Ile
         115                 120                 125            
 Tyr Gly Ile Glu Asn Lys Tyr Asn Thr Gln
     130                 135            



      <210> 2881
      <211> 139
      <212> PRT
      <213> Homo sapiens


      <400> 2881
 Lys Tyr Phe Lys Cys Ala Pro Phe Pro Pro Ala Thr Arg Pro Lys Ala
   1               5                  10                  15    
 His Thr Val Phe Leu Lys Asn Val Asp Ile Gln Val Asn Leu Arg Phe
              20                  25                  30        
 Cys Ser Lys Val Ala Lys Leu His Tyr Pro Asn Asn Leu Leu Phe His
          35                  40                  45            
 Ser Leu Gly Ile Thr Lys Met Gln Leu Asp Arg Lys Glu Leu Ala Val
      50                  55                  60                
 Val Gln Ser His Ser Gly Ser Lys Gly Arg Ile Leu Phe Ser Pro Ser
  65                  70                  75                  80
 Leu Pro Ala Leu Glu Gln Leu Arg Val Pro Leu Glu Glu His Ser Ala
                  85                  90                  95    
 Ser Pro Asp Pro Ile His Pro Pro Ser Leu Ala Pro Glu Arg Ala Ala
             100                 105                 110        
 Ser Pro Gly Pro Pro Thr Gly Ala Glu Thr Arg Val Pro Ala Pro His
         115                 120                 125            
 Ala Gly Thr Asp Pro Ser Glu Pro Pro Arg Arg
     130                 135                



      <210> 2882
      <211> 121
      <212> PRT
      <213> Homo sapiens


      <400> 2882
 Ala Arg Pro Arg Val Val Leu Lys Arg Leu Gly Ser Gln Arg Glu Leu
   1               5                  10                  15    
 Ala Gln Leu Gly Pro Glu His Leu Gln Ala Gly His Arg Pro Ala Pro
              20                  25                  30        
 Leu Arg Pro Ala Ala Gly His Ala Pro Asp Arg Val Arg Ala Pro Gln
          35                  40                  45            
 Arg Arg Arg Ala Ser Ala His Ala Arg Gly Ser Gly Gly Leu Val Gly
      50                  55                  60                
 Pro Gly Ala Leu Pro Leu Ala Ala Pro Ser Arg Pro Pro Gly Ala Pro
  65                  70                  75                  80
 Leu Arg Gly Asp Gln Gly Leu Gly Gln Leu Pro Ala Ser Gln Pro Gln
                  85                  90                  95    
 Gly Leu Gly Ala His Ala Ala Ala Ala Asp Pro Gly Leu Gln Pro Arg
             100                 105                 110        
 Ala Ala Gly Ala Thr Glu Phe Ser Val
         115                 120    



      <210> 2883
      <211> 466
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(466)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2883
 Arg Gln Glu Asn Asn Thr Arg Gly Val Pro Ser Leu Leu Lys Ser Phe
   1               5                  10                  15    
 Leu Gln Glu Arg Leu Gly Ile His Leu Ile Arg Arg Lys Ile Val Lys
              20                  25                  30        
 Pro Lys His His Val Leu Met Ser Arg Lys Glu Ser Trp Lys Val Lys
          35                  40                  45            
 Ser Glu Ile Pro Lys Val Pro Lys Gln Pro Leu Val Leu His His Pro
      50                  55                  60                
 Arg Met Thr Thr Thr Lys Ser Pro Ser Lys Asp Met Leu Glu Pro Glu
  65                  70                  75                  80
 Ala Glu Leu Ala Glu Asp Leu Pro Thr Thr Lys Ser Thr Ser Val Glu
                  85                  90                  95    
 Ser Glu Asp Ala His Xaa Glu Pro Gly Arg Pro Phe Pro Val Leu Pro
             100                 105                 110        
 Asp Leu Pro Cys His Cys Leu Pro Ser Ala Pro Thr Pro Leu Cys Ile
         115                 120                 125            
 Val Lys Arg Pro Cys Pro Thr Xaa Val Thr Gln Leu Ser Ala Ser Ala
     130                 135                 140                
 Gln Ser Ala His Gln Met Arg Thr Pro Arg Ala Gln Ser Pro Ser Ser
 145                 150                 155                 160
 Xaa Pro Arg Xaa Val Asn Cys Leu Pro Pro Ser Leu His Lys Asp Asp
                 165                 170                 175    
 Leu Glu Leu Lys Glu Lys Asp Gln Lys Lys Pro Pro Thr Ala Pro Arg
             180                 185                 190        
 Glu Val Lys Gly Thr Arg Arg Lys Leu Pro Thr Ala Phe Leu Pro Ser
         195                 200                 205            
 Lys Tyr His Gly Tyr Glu Glu Leu Leu Thr Ala Lys Pro Asp Pro Ala
     210                 215                 220                
 Phe Ile Glu Pro Lys Gly Ile Gln Lys Asn Ala Pro Ser Pro Ala Thr
 225                 230                 235                 240
 Asn Ala Glu Ala Pro Thr Pro Val Pro Leu Leu Gln Ala Gln Ala Gly
                 245                 250                 255    
 His Ser Ser Glu Thr Leu Cys Ser Gln Arg Glu Thr Gly Pro Glu Asn
             260                 265                 270        
 Pro Asp Ser Thr Pro Lys Glu Asp Xaa Ser Pro Thr Ser Gly Xaa His
         275                 280                 285            
 Leu His Ser Leu Ala Gly Ser Pro Glu His Tyr Arg Gly Ser Thr Arg
     290                 295                 300                
 Cys Cys Pro Ala Pro Val Asp Arg Thr Ala Ala Gly Glu Pro Ala Ser
 305                 310                 315                 320
 Ser Thr Trp Arg Pro Arg Gly Cys Xaa Arg Ser Ser Arg His Val Thr
                 325                 330                 335    
 Gly Ser Trp Xaa Val Ala Leu Cys Ala Gln Cys Ser Gly Leu Pro Arg
             340                 345                 350        
 Ser Pro Trp Pro Ala Gln Arg Xaa Val Arg Ala Ser Pro Ser Ser Ala
         355                 360                 365            
 Thr Ser Ser Ser Ser Trp Met Ser Ser Ala Arg Ser Pro Gln Pro Val
     370                 375                 380                
 Thr His Lys Ala Arg Ala Val His Gly Gly Cys Val His His Pro Ala
 385                 390                 395                 400
 Cys Ala Pro Ala Leu Pro Glu Gly Ser Val Pro Trp Thr Ala Pro Gln
                 405                 410                 415    
 Gly Xaa Pro Ala Gly His Arg Pro Gln Ser Ser Ala Gly Pro His Leu
             420                 425                 430        
 Leu Ala Thr Arg Trp His Pro Leu Val Arg Ile Ser Pro Pro Trp Pro
         435                 440                 445            
 Arg His Asp Leu Val Pro Gly Pro Ala Ala Ile Lys Ser Gly Cys Thr
     450                 455                 460                
 Gly Gln
 465    



      <210> 2884
      <211> 103
      <212> PRT
      <213> Homo sapiens


      <400> 2884
 Met Leu Ile Gly Leu Leu Ala Trp Leu Gln Thr Val Pro Ala His Gly
   1               5                  10                  15    
 Cys Gln Phe Leu Pro Ile Thr Ser Val Thr Ala Thr Val Tyr His Leu
              20                  25                  30        
 Pro Val His Gln Leu Lys Gly Arg Ser Arg Val Gln Lys Asn Leu Thr
          35                  40                  45            
 Leu Asp Asn Glu Gly Glu Gly Thr Trp Thr Thr Cys Leu Glu Phe Leu
      50                  55                  60                
 Glu Ser Leu Ala Gly Trp Arg Leu Gly Trp Gly Val Ser Arg Gly Val
  65                  70                  75                  80
 Arg Glu Trp Leu Cys Leu Gln Gln Val Ser Leu His Gln Thr Pro Gly
                  85                  90                  95    
 Leu Pro His Lys Gln Asp Leu
             100            



      <210> 2885
      <211> 233
      <212> PRT
      <213> Homo sapiens


      <400> 2885
 Glu Arg Ser Thr Tyr Asp Leu Arg Ser Ser Asp Arg Pro Ala Gln Glu
   1               5                  10                  15    
 Thr Ser His Gln Phe Gln Ile His Leu Pro Cys Val Leu Leu Leu Tyr
              20                  25                  30        
 Ser Pro Thr Leu Thr Leu Lys Tyr Ile Ser Thr Pro Ser Leu Ala Thr
          35                  40                  45            
 Asp His Ala Pro Leu Thr Ile Ser Leu Lys Pro Asn His Pro Tyr Pro
      50                  55                  60                
 Ala Gln Cys Gln Tyr Pro Ile Pro Gln His Ala Leu Lys Gly Leu Lys
  65                  70                  75                  80
 Pro Ala Ile Thr Arg Leu Leu Gln His Gly Leu Leu Lys Pro Ile Asn
                  85                  90                  95    
 Ser Pro Tyr Asn Ser Pro Ile Leu Pro Val Leu Glu Pro Glu Lys Ile
             100                 105                 110        
 Tyr Arg Leu Val Gln Asp Leu Arg Leu Ile Asn Gln Ile Val Leu Pro
         115                 120                 125            
 Ile His Pro Val Val Pro Asn Pro Tyr Thr Leu Leu Ser Ser Ile Pro
     130                 135                 140                
 Pro Ser Thr Ile His Tyr Ser Val Leu Asp Leu Lys Arg Ala Phe Phe
 145                 150                 155                 160
 Thr Ile Pro Leu Tyr Pro Ser Ser Gln Pro Leu Phe Ala Phe Thr Trp
                 165                 170                 175    
 Thr Asp Pro Asp Thr Leu Gln Ala Gln Gln Ile Thr Trp Ala Val Leu
             180                 185                 190        
 Pro Gln Ser Phe Thr Asp Ser Pro His Tyr Phe Ser Gln Ala Gln Ile
         195                 200                 205            
 Ser Ser Leu Ser Val Thr Tyr Leu Ser Ile Ile Leu Ile Lys Thr His
     210                 215                 220                
 Thr Leu Ser Leu Leu Ile Met Ser Asp
 225                 230            



      <210> 2886
      <211> 124
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(124)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2886
 Thr Pro Ala Trp Met Thr Glu Arg Asp Cys Ile Trp Arg Arg Arg Thr
   1               5                  10                  15    
 Ser Ala Pro Gly Gly Ser Trp Pro Ser Gly Pro Val Pro Ser Pro Gly
              20                  25                  30        
 Ala Gln Xaa Arg Pro Pro Ser Gln Gly Leu Gly Leu Trp Trp Ala Ala
          35                  40                  45            
 Ala Ala Ala Pro Arg Cys Xaa Thr Ala Pro Gly Pro Arg Pro Pro Pro
      50                  55                  60                
 His Gly Pro Gly Ser Pro Gln Gly Ala Ser Pro Pro Thr Arg Pro Pro
  65                  70                  75                  80
 Arg Cys Arg Pro His Pro Arg Ala Gly Ser Ala Gly Pro Thr Gly Ala
                  85                  90                  95    
 Thr Pro Pro Gly Ser Thr Gln Gly Gln Arg Arg Arg His Ser His Gln
             100                 105                 110        
 Leu Pro Gly His Pro Gly His Arg Val Ala Leu Gly
         115                 120                



      <210> 2887
      <211> 208
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(208)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2887
 His Ile Leu Arg Arg Gln Glu Phe Phe Phe Phe Cys Leu Phe Val Cys
   1               5                  10                  15    
 Leu Arg Trp Val Leu Val Leu Leu Pro Arg Leu Glu Xaa Cys Gly Met
              20                  25                  30        
 Ile Leu Ala His Cys Asn Leu Phe Leu Leu Gly Ser Ser Asn Ser Pro
          35                  40                  45            
 Ala Ser Ala Ser Xaa Val Ala Gly Thr Thr Gly Val Arg His His Ala
      50                  55                  60                
 Trp Ile Ile Phe Cys Ile Leu Val Glu Thr Glu Phe His Arg Val Ala
  65                  70                  75                  80
 Gln Thr Asp Leu Glu Leu Leu Ser Ser Gly Asn Pro Pro Ala Ser Ala
                  85                  90                  95    
 Ser Xaa Ser Ala Gly Ile Ile Gly Val Ser His Ser Ala Trp Pro Glu
             100                 105                 110        
 Ser Cys Arg Tyr Ala Arg Arg Lys Cys Phe Cys Val Lys Lys Leu Arg
         115                 120                 125            
 Arg Trp Lys Leu Asn Pro Leu Cys Ile Gln Lys Ala Val Ser Glu Gly
     130                 135                 140                
 His Cys Trp Gln Ala Ser Pro Tyr Arg Asp Ser Ala Val Arg Glu Gln
 145                 150                 155                 160
 Ser Ile Trp Gly Thr Thr Ala Ser Ser Gly Gly Ala Arg Met Arg Trp
                 165                 170                 175    
 Ser Ser Pro Ala Ala Leu Tyr Val Arg Leu Leu Ala Gly Phe Ser Phe
             180                 185                 190        
 Ile Asn Lys Leu Val Ala Ser Glu Tyr Arg Val Phe Ser Ser Thr Leu
         195                 200                 205            





      <210> 2888
      <211> 832
      <212> PRT
      <213> Homo sapiens


      <400> 2888
 Asn Ser His Arg Trp Val Tyr Val Arg Ala Arg Arg Trp Arg Arg Arg
   1               5                  10                  15    
 Gly Lys Gln Arg Glu Gln Pro Glu Asp Arg Gly Val Pro Met Lys Arg
              20                  25                  30        
 Ala Ala Met Ala Leu His Ser Pro Gln Tyr Ile Phe Gly Asp Phe Ser
          35                  40                  45            
 Pro Asp Glu Phe Asn Gln Phe Phe Val Thr Pro Arg Ser Ser Val Glu
      50                  55                  60                
 Leu Pro Pro Tyr Ser Gly Thr Val Leu Cys Gly Thr Gln Ala Val Asp
  65                  70                  75                  80
 Lys Leu Pro Asp Gly Gln Glu Tyr Gln Arg Ile Glu Phe Gly Val Asp
                  85                  90                  95    
 Glu Val Ile Glu Pro Ser Asp Thr Leu Pro Arg Thr Pro Ser Tyr Ser
             100                 105                 110        
 Ile Ser Ser Thr Leu Asn Pro Gln Ala Pro Glu Phe Ile Leu Gly Cys
         115                 120                 125            
 Thr Ala Ser Lys Ile Thr Pro Asp Gly Ile Thr Lys Glu Ala Ser Tyr
     130                 135                 140                
 Gly Ser Ile Asp Cys Gln Tyr Pro Gly Ser Ala Leu Ala Leu Asp Gly
 145                 150                 155                 160
 Ser Ser Asn Val Glu Ala Glu Val Leu Glu Asn Asp Gly Val Ser Gly
                 165                 170                 175    
 Gly Leu Gly Gln Arg Glu Arg Lys Lys Lys Lys Lys Arg Pro Pro Gly
             180                 185                 190        
 Tyr Tyr Ser Tyr Leu Lys Asp Gly Gly Asp Asp Ser Ile Ser Thr Glu
         195                 200                 205            
 Ala Leu Val Asn Gly His Ala Asn Ser Ala Val Pro Asn Ser Val Ser
     210                 215                 220                
 Ala Glu Asp Ala Glu Phe Met Gly Asp Met Pro Pro Ser Val Thr Pro
 225                 230                 235                 240
 Arg Thr Cys Asn Ser Pro Gln Asn Ser Thr Asp Ser Val Ser Asp Ile
                 245                 250                 255    
 Val Pro Asp Ser Pro Phe Pro Gly Ala Leu Gly Ser Asp Thr Arg Thr
             260                 265                 270        
 Ala Gly Gln Pro Glu Gly Gly Pro Gly Ala Asp Phe Gly Gln Ser Cys
         275                 280                 285            
 Phe Pro Ala Glu Ala Gly Arg Asp Thr Leu Ser Arg Thr Ala Gly Ala
     290                 295                 300                
 Gln Pro Cys Val Gly Thr Asp Thr Thr Glu Asn Leu Gly Val Ala Asn
 305                 310                 315                 320
 Gly Gln Ile Leu Glu Ser Ser Gly Glu Gly Thr Ala Thr Asn Gly Val
                 325                 330                 335    
 Glu Leu His Thr Thr Glu Ser Ile Asp Leu Asp Pro Thr Lys Pro Glu
             340                 345                 350        
 Ser Ala Ser Pro Pro Ala Asp Gly Thr Gly Ser Ala Ser Gly Thr Leu
         355                 360                 365            
 Pro Val Ser Gln Pro Lys Ser Trp Ala Ser Leu Phe His Asp Ser Lys
     370                 375                 380                
 Pro Ser Ser Ser Ser Pro Val Ala Tyr Val Glu Thr Lys Tyr Ser Pro
 385                 390                 395                 400
 Pro Ala Ile Ser Pro Leu Val Ser Glu Lys Gln Val Glu Val Lys Glu
                 405                 410                 415    
 Gly Leu Val Pro Val Ser Glu Asp Pro Val Ala Ile Lys Ile Ala Glu
             420                 425                 430        
 Leu Leu Glu Asn Val Thr Leu Ile His Lys Pro Val Ser Leu Gln Pro
         435                 440                 445            
 Arg Gly Leu Ile Asn Lys Gly Asn Trp Cys Tyr Ile Asn Ala Thr Leu
     450                 455                 460                
 Gln Ala Leu Val Ala Cys Pro Pro Met Tyr His Leu Met Lys Phe Ile
 465                 470                 475                 480
 Pro Leu Tyr Ser Lys Val Gln Arg Pro Cys Thr Ser Thr Pro Met Ile
                 485                 490                 495    
 Asp Ser Phe Val Arg Leu Met Asn Glu Phe Thr Asn Met Pro Val Pro
             500                 505                 510        
 Pro Lys Pro Arg Gln Ala Leu Gly Asp Lys Ile Val Arg Asp Ile Arg
         515                 520                 525            
 Pro Gly Ala Ala Phe Glu Pro Thr Tyr Ile Tyr Arg Leu Leu Thr Val
     530                 535                 540                
 Asn Lys Ser Ser Leu Ser Glu Lys Gly Arg Gln Glu Asp Ala Glu Glu
 545                 550                 555                 560
 Tyr Leu Gly Phe Ile Leu Asn Gly Leu His Glu Glu Met Leu Asn Leu
                 565                 570                 575    
 Lys Lys Leu Leu Ser Pro Ser Asn Glu Lys Leu Thr Ile Ser Asn Gly
             580                 585                 590        
 Pro Lys Asn His Ser Val Asn Glu Glu Glu Gln Glu Glu Gln Gly Glu
         595                 600                 605            
 Gly Ser Glu Asp Glu Trp Glu Gln Val Gly Pro Arg Asn Lys Thr Ser
     610                 615                 620                
 Val Thr Arg Gln Ala Asp Phe Val Gln Thr Pro Ile Thr Gly Ile Phe
 625                 630                 635                 640
 Gly Gly His Ile Arg Ser Val Val Tyr Gln Gln Ser Ser Lys Glu Ser
                 645                 650                 655    
 Ala Thr Leu Gln Pro Phe Phe Thr Leu Gln Leu Asp Ile Gln Ser Asp
             660                 665                 670        
 Lys Ile Arg Thr Val Gln Asp Ala Leu Glu Ser Leu Val Ala Arg Glu
         675                 680                 685            
 Ser Val Gln Gly Tyr Thr Thr Lys Thr Lys Gln Glu Val Glu Ile Ser
     690                 695                 700                
 Arg Arg Val Thr Leu Glu Lys Leu Pro Pro Val Leu Val Leu His Leu
 705                 710                 715                 720
 Lys Arg Phe Val Tyr Glu Lys Thr Gly Gly Cys Gln Lys Leu Ile Lys
                 725                 730                 735    
 Asn Ile Glu Tyr Pro Val Asp Leu Glu Ile Ser Lys Glu Leu Leu Ser
             740                 745                 750        
 Pro Gly Val Lys Asn Lys Asn Phe Lys Cys His Arg Thr Tyr Arg Leu
         755                 760                 765            
 Phe Ala Val Val Tyr His His Gly Asn Ser Ala Thr Gly Gly His Tyr
     770                 775                 780                
 Thr Thr Asp Val Phe Gln Ile Gly Leu Asn Gly Trp Leu Arg Ile Asp
 785                 790                 795                 800
 Asp Gln Thr Val Lys Val Ile Asn Gln Tyr Gln Val Val Lys Pro Thr
                 805                 810                 815    
 Ala Glu Arg Thr Ala Tyr Leu Leu Tyr Tyr Arg Arg Val Asp Leu Leu
             820                 825                 830        





      <210> 2889
      <211> 111
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(111)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2889
 Phe Arg Arg Pro Arg Arg Ala Asn Arg Phe Arg Ser Arg Ile Arg Asn
   1               5                  10                  15    
 Gln Pro Gly Pro His Gly Glu Thr Pro Phe Phe Leu Xaa Ile Pro Lys
              20                  25                  30        
 Leu Ala Arg His Gly Gly Gly Cys Pro Xaa Ser Pro Leu Leu Arg Arg
          35                  40                  45            
 Val Arg Pro Glu Asn Pro Phe Asn Pro Gly Ser Arg Gly Phe Asn Xaa
      50                  55                  60                
 Leu Lys Pro Gln Pro Cys Pro Pro Thr Trp Val Thr Glu Xaa Asp Ser
  65                  70                  75                  80
 Val Ser Lys Thr Asn Lys Gln Pro Pro Pro Thr Lys Lys Asn Arg Asp
                  85                  90                  95    
 Gly Arg Trp Gly Ala Ile Trp Glu Ser Gln Met Glu Thr Trp Ser
             100                 105                 110    



      <210> 2890
      <211> 145
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(145)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2890
 Gly Lys Gly Gly Cys Gly Gln Thr Arg Arg Cys Ala Arg Pro Gly Arg
   1               5                  10                  15    
 His His Ala Ala Pro Ala Leu Arg Ala Asp Arg Thr Gly Pro Ala Pro
              20                  25                  30        
 Arg Arg Gly Leu Phe Gly Arg Cys Arg Thr Leu Gln Pro Ser Ala Arg
          35                  40                  45            
 Arg Leu Ser Ser Glu His Ser Val Xaa Gln Thr His Gly Cys Ala Thr
      50                  55                  60                
 Pro Ser Arg Cys His Gly Gly Asp Gly Arg Glu Asp Arg Gly Ser Pro
  65                  70                  75                  80
 Gly Asp Arg Gly Glu Arg Pro Ala Gly Pro Ala Gly Gly Ala Gly Leu
                  85                  90                  95    
 Glu Pro Ala Pro Gly Thr Leu Gln Pro Arg Ser Arg Pro Ser Arg Arg
             100                 105                 110        
 Trp Leu Leu Ser Pro Gly Ala Gly Ala Gln Gln Leu Glu Val Val His
         115                 120                 125            
 Leu Pro Gly Gln Arg Pro Gln Asn Gln Pro Cys Pro Leu Asp Phe Leu
     130                 135                 140                
 Pro
 145



      <210> 2891
      <211> 401
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(401)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2891
 Phe Phe Phe Pro Val Pro Pro Pro Leu Phe Thr Asp Pro Arg Ala Pro
   1               5                  10                  15    
 Gln Pro His Arg His Leu Ala Phe Arg Gly His Arg Lys Glu Lys Gly
              20                  25                  30        
 Pro Gly Asp Pro Pro Ser Thr Pro Gln Ser Gln Ala Asp Pro Ala Ala
          35                  40                  45            
 Ala Pro Gln Gly Gln Pro Gly Cys Arg Leu Pro Arg Gly His Cys Asp
      50                  55                  60                
 Arg Arg His Gln Glu Ala Arg Pro Gly Cys Trp Gly Pro Pro Gly Gly
  65                  70                  75                  80
 Pro Gly Ser Ile Leu Gly Pro Lys Ser Trp Cys His Leu Glu Ala Asp
                  85                  90                  95    
 Ser Gly Lys Arg Pro Gly Trp Thr Val Gly Val Gly Val Arg Ser Ser
             100                 105                 110        
 Pro Ala Cys Pro Gly His Val Glu Gln Gln Gly Ser Ala Gly Ser Pro
         115                 120                 125            
 Gly Trp Met Gly Trp Gly Cys Pro Cys Pro Val Ser Xaa Pro Leu Gln
     130                 135                 140                
 Gly Gln Asn Gln Pro Ser Pro Ser Ser Leu Gly Gly Ser Arg Gly Ser
 145                 150                 155                 160
 Phe Phe Ser Pro Pro Asp Pro Ala Gly Gly Gln Gly Gln Glu Gly Glu
                 165                 170                 175    
 Gly Arg Gly Glu Arg Ser Gly Gln Gly Pro Trp Gly Pro Gly Ser Phe
             180                 185                 190        
 Lys Asn Ala Arg Gln Val Ala Gly Gly Gly Gln Glu Gly Gly Gln Gly
         195                 200                 205            
 Pro Asp Pro His Asp Gly Gly Ser Leu Arg Pro Pro Arg Met Lys Glu
     210                 215                 220                
 Gly Gly Leu Gly Arg Arg Gly Arg Pro Gln Pro Ser Val Thr Pro Val
 225                 230                 235                 240
 Leu Gly Ser Ala Ala Arg Trp Ser Lys Ala Pro Pro Ser Gln Gly Gln
                 245                 250                 255    
 Asp His Arg Thr Gly Gly Asn Arg His Leu Ala Pro Xaa Ser Ser Gly
             260                 265                 270        
 Gly Arg Gly Gly Ala Pro Gly Ala Leu Gly Leu Pro Trp His Pro Ala
         275                 280                 285            
 Cys Ser Gly Ala Ser Gly His Ser Gly Arg Trp Ala Xaa Arg Ser Ser
     290                 295                 300                
 Gly Trp Gly Xaa Gly Pro Ser Pro His Thr Pro Pro Pro Gly Pro Ala
 305                 310                 315                 320
 Arg His Pro Ala Pro Gly Leu Ala Gly Leu Ala Pro His Pro Ala Arg
                 325                 330                 335    
 Leu Arg Lys Xaa Ser Gly Arg Ser Pro Arg Glu Ala Gly Val Lys Ile
             340                 345                 350        
 Ser Leu Leu Leu Gly Gly Glu Arg Gly Leu Pro Gly Pro Leu Ala Val
         355                 360                 365            
 Val His Asp Ser Gly Asp Gly Gly Ala Gly His Arg Gly Gly Val Xaa
     370                 375                 380                
 Ser Xaa Arg Ser Pro Pro Asp Pro Leu Ser Leu Ser Pro Arg Pro Ala
 385                 390                 395                 400
 Ala
    



      <210> 2892
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 2892
 Ser Ala Phe Ser Tyr Ile Pro Pro Arg Arg Leu Asp Pro Thr Glu His
   1               5                  10                  15    
 Ser Tyr Tyr Tyr Arg Pro Ala Arg Glu Gln Glu Arg Pro Ala Gly Val
              20                  25                  30        
 Leu Thr Ser Ser Val Tyr Gly Lys Arg Ile Asn Gln Pro Ile Glu Pro
          35                  40                  45            
 Leu Asn Arg Asp Phe Gly Arg Ala Asn His Val Gln Ala Asp Phe Tyr
      50                  55                  60                
 Arg Lys Asn Asp Ile Pro Ser Leu Lys Glu Pro Gly Phe Gly His Ile
  65                  70                  75                  80
 Ala Pro Ser
            



      <210> 2893
      <211> 1142
      <212> PRT
      <213> Homo sapiens


      <400> 2893
 Met Ala Gly Gly Gln Glu Val Glu Ala Val Val Ala Asp Gln Leu Cys
   1               5                  10                  15    
 Ala Lys Tyr Ser Lys Glu Tyr Gly Lys Leu Cys Arg Thr Asn Gln Ile
              20                  25                  30        
 Gly Thr Val Asn Asp Arg Leu Met His Lys Leu Ser Val Glu Ala Pro
          35                  40                  45            
 Pro Lys Ile Leu Val Glu Arg Tyr Leu Ile Glu Ile Ala Lys Asn Tyr
      50                  55                  60                
 Asn Val Pro Tyr Glu Pro Asp Ser Val Val Met Val Glu Asp Ile Leu
  65                  70                  75                  80
 Glu Met Ser Leu Val Glu Phe Gly Asn Ile Gly Glu Ala Phe Leu Glu
                  85                  90                  95    
 Gln Asn Gln Ser Pro Glu Ser Ser Val Thr Leu Thr Ser Ala Asn Ala
             100                 105                 110        
 Thr Leu Leu Leu Ser Arg Gln Asn Ile Ser Thr Leu Pro Leu Ser Ser
         115                 120                 125            
 Tyr Thr Leu Gly His Pro Ala Pro Val Arg Leu Gly Phe Pro Ser Ala
     130                 135                 140                
 Leu Ala Leu Lys Glu Leu Leu Asn Lys His Pro Gly Val Asn Val Gln
 145                 150                 155                 160
 Val Phe Ala Leu Asp Pro Val Leu Gly Thr Phe Leu Ile Leu Thr Ser
                 165                 170                 175    
 Val Ile Leu Met Val Leu Val Val Ile Asn Leu Phe Val Ser Ala Ile
             180                 185                 190        
 Leu Met Ala Phe Gly Lys Glu Arg Lys Ser Leu Lys Val Val Met Gln
         195                 200                 205            
 Ser Asn Thr Ile Cys Tyr Arg Glu Asn Arg Ile Ser Thr Val Pro Pro
     210                 215                 220                
 Ser Gly Thr Arg Glu Thr Ala Arg Lys Ala Lys Gly His Arg Gly Leu
 225                 230                 235                 240
 Pro Glu Asn Pro Val Gln Leu Ser Glu Ala Phe Asn Cys Gln Asp Lys
                 245                 250                 255    
 Leu Cys Asn Trp Ile Pro Val Gly Gln Cys Pro Ala Ala Arg Ser Thr
             260                 265                 270        
 Val Tyr Ala Asn Glu Arg Ala Gln Leu Pro Gly Thr Val Thr Met Ala
         275                 280                 285            
 Ser Arg Val Ile Phe Pro Leu Pro Leu Ala Phe Glu Ser Leu His Thr
     290                 295                 300                
 Pro Gly Lys Ser Ser Ser Gln Gly Ser Asp Ala Gly Ala Gly Pro Pro
 305                 310                 315                 320
 Ile Leu Gly Leu Phe Cys Pro Trp Thr Arg Gly Pro Arg Leu Ser Ala
                 325                 330                 335    
 Leu Arg Ala Arg Arg Leu Ser Ser Pro Ile Ala Asp Val Asn Lys Asn
             340                 345                 350        
 Ile Pro Pro Ser Lys His Arg Thr Ile Leu Ser Ser Arg Pro Asp Gly
         355                 360                 365            
 Ser Ile Leu Phe Leu Pro Pro Phe Phe Val Val Thr Ile Thr Pro Pro
     370                 375                 380                
 Ala Arg Ala Asp Val Gln Glu Lys Asp Gly His Thr Ile Glu Gln Asp
 385                 390                 395                 400
 Glu Gly Glu Arg Gln His Gln Ile Glu Lys Thr Glu Glu Glu Asn Thr
                 405                 410                 415    
 Asn Lys Pro Lys Arg Lys Gln Lys Leu Ala Pro Gly Thr Pro Gln Ser
             420                 425                 430        
 Asn Met Lys Pro Val His Glu Arg Ser Gln Glu Cys Leu Pro Pro Lys
         435                 440                 445            
 Lys Arg Asp Leu Pro Val Thr Ser Glu Asp Met Gly Arg Thr Thr Ser
     450                 455                 460                
 Cys Ser Thr Asn His Thr Pro Ser Ser Asp Ala Ser Glu Trp Ser Arg
 465                 470                 475                 480
 Gly Val Val Val Ala Gly Gln Ser Gln Ala Gly Ala Arg Val Ser Leu
                 485                 490                 495    
 Gly Gly Asp Gly Ala Glu Ala Ile Thr Gly Leu Thr Val Asp Gln Tyr
             500                 505                 510        
 Gly Met Leu Tyr Lys Val Ala Val Pro Pro Ala Thr Phe Ser Pro Thr
         515                 520                 525            
 Gly Leu Pro Ser Val Val Asn Met Ser Pro Leu Pro Pro Thr Phe Asn
     530                 535                 540                
 Val Ala Ser Ser Leu Ile Gln His Pro Gly Ile His Tyr Pro Pro Leu
 545                 550                 555                 560
 His Tyr Ala Gln Leu Pro Ser Thr Ser Leu Gln Phe Ile Gly Ser Pro
                 565                 570                 575    
 Tyr Ser Leu Pro Tyr Ala Val Pro Pro Asn Phe Leu Pro Ser Pro Leu
             580                 585                 590        
 Leu Ser Pro Ser Ala Asn Leu Ala Thr Ser His Leu Pro His Phe Val
         595                 600                 605            
 Pro Tyr Ala Ser Leu Leu Ala Glu Gly Ala Thr Pro Pro Pro Gln Ala
     610                 615                 620                
 Pro Ser Pro Ala His Ser Phe Asn Lys Ala Pro Ser Ala Thr Ser Pro
 625                 630                 635                 640
 Ser Gly Gln Leu Pro His His Ser Ser Thr Gln Pro Leu Asp Leu Ala
                 645                 650                 655    
 Pro Gly Arg Met Pro Ile Tyr Tyr Gln Met Ser Arg Leu Pro Ala Gly
             660                 665                 670        
 Tyr Thr Leu His Glu Thr Pro Pro Ala Gly Ala Ser Pro Val Leu Thr
         675                 680                 685            
 Pro Gln Glu Ser Gln Ser Ala Leu Glu Ala Ala Ala Ala Asn Gly Gly
     690                 695                 700                
 Gln Arg Pro Arg Glu Arg Asn Leu Val Arg Arg Glu Ser Glu Ala Leu
 705                 710                 715                 720
 Asp Ser Pro Asn Ser Lys Gly Glu Gly Gln Gly Leu Val Pro Val Val
                 725                 730                 735    
 Glu Cys Val Val Asp Gly Gln Leu Phe Ser Gly Ser Gln Thr Pro Arg
             740                 745                 750        
 Val Glu Val Ala Ala Pro Ala His Arg Gly Thr Pro Asp Thr Asp Leu
         755                 760                 765            
 Glu Val Gln Arg Val Val Ala Ser Gln Val Gly Pro Gln Ser Thr Ile
     770                 775                 780                
 Leu Arg Thr Gln Cys Leu Cys Asn His Leu Thr Phe Phe Ala Ser Asp
 785                 790                 795                 800
 Phe Phe Val Val Pro Arg Thr Val Asn Val Glu Asp Thr Ile Lys Leu
                 805                 810                 815    
 Phe Leu Arg Val Thr Asn Asn Pro Val Gly Val Ser Leu Leu Ala Ser
             820                 825                 830        
 Leu Leu Gly Phe Tyr Val Ile Thr Val Val Trp Ala Arg Lys Lys Asp
         835                 840                 845            
 Gln Ala Asp Met Gln Lys Gly Cys Gln Thr Pro Ala Gly Val His Pro
     850                 855                 860                
 Pro Ala Pro Gln Leu Glu Glu Ala Gly Thr Ile Pro Ser Gly Gly Leu
 865                 870                 875                 880
 Val Lys Val Thr Val Leu Ala Asp Asn Asp Pro Ser Ala Gln Phe His
                 885                 890                 895    
 Tyr Leu Ile Gln Val Tyr Thr Gly Tyr Arg Arg Ser Ala Ala Thr Thr
             900                 905                 910        
 Ala Lys Leu Ser Val Tyr Leu Ile Leu Pro Gly Cys Arg Thr Arg Thr
         915                 920                 925            
 Arg Asp Pro Leu Ser Gly Val Gly Ser Arg Pro Val Ala Gly Ala Glu
     930                 935                 940                
 Tyr Arg Leu Pro Gly Gln Phe Gly Arg Thr Ser Thr Val Ala Ala Ser
 945                 950                 955                 960
 Asn Thr Gln Ala Glu Gly Ala Ala Gly His Arg Gly Phe Trp Leu Ala
                 965                 970                 975    
 Lys Gln His Pro Lys Asp Ala Val Thr Leu Glu Leu Arg Cys Thr Pro
             980                 985                 990        
 Cys Arg Ser Ile Ala Arg Leu Ser Asp Ala Gly Gly Val Pro Ala Gly
         995                1000                1005            
 Ala Arg Arg Val Arg Cys Ala Ala Val Leu Ala Asn Cys Ser Leu Asp
    1010                1015                1020                
 Met Lys Arg Gly Val Cys Ala Ser Arg Ser Ala Thr Val Arg Lys Arg
1025                1030                1035                1040
 Ser Asp Lys Asp Val Glu Glu Leu Gly Asp Arg Glu Ser Ala Val Gly
                1045                1050                1055    
 Val Ser Asp Phe Leu Asp Gly Asp Ala His Tyr Glu Arg Asn Gly Asn
            1060                1065                1070        
 Asn Ser His Leu Tyr Gln Arg His Lys Lys Thr Lys Arg Gly Val Ala
        1075                1080                1085            
 Ile Ala Arg Asp Lys Met Pro Pro Asp Phe Gln Asp His Val Ile Pro
    1090                1095                1100                
 Gly Gln Glu Ile Lys Ala Lys Ser Phe Tyr Ser Pro Val Asp Ser Asp
1105                1110                1115                1120
 Glu Thr Gly Asp Lys Ile Arg Tyr Asn Ser Lys Arg Arg His Trp Arg
                1125                1130                1135    
 Thr Gly Met Leu Gly Leu
            1140        



      <210> 2894
      <211> 256
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(256)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2894
 Glu Asn Phe Gln His Phe Met Asp Arg Ile Ser Asn Gly Gly Leu Glu
   1               5                  10                  15    
 Glu Gly Lys Pro Val Asp Leu Val Leu Ser Cys Val Asp Asn Phe Glu
              20                  25                  30        
 Ala Arg Met Thr Ile Asn Thr Ala Cys Asn Glu Leu Gly Gln Thr Trp
          35                  40                  45            
 Met Glu Ser Gly Val Ser Glu Asn Ala Val Ser Gly His Ile Gln Leu
      50                  55                  60                
 Ile Ile Pro Gly Glu Ser Ala Cys Phe Ala Cys Ala Pro Pro Leu Val
  65                  70                  75                  80
 Val Ala Ala Asn Ile Asp Glu Lys Thr Leu Lys Arg Glu Gly Val Cys
                  85                  90                  95    
 Ala Ala Ser Leu Pro Thr Thr Met Gly Val Val Ala Gly Ile Leu Val
             100                 105                 110        
 Gln Asn Val Leu Lys Phe Leu Leu Asn Phe Gly Thr Val Ser Phe Tyr
         115                 120                 125            
 Leu Gly Tyr Asn Ala Met Gln Asp Phe Phe Pro Thr Met Ser Met Lys
     130                 135                 140                
 Pro Asn Pro Gln Cys Asp Asp Arg Asn Cys Arg Lys Gln Gln Glu Glu
 145                 150                 155                 160
 Tyr Lys Lys Lys Val Ala Ala Leu Pro Lys Gln Glu Val Ile Gln Glu
                 165                 170                 175    
 Glu Glu Glu Ile Ile His Glu Asp Asn Glu Trp Gly Ile Glu Leu Val
             180                 185                 190        
 Ser Glu Val Ser Glu Glu Glu Leu Lys Asn Phe Ser Gly Pro Val Pro
         195                 200                 205            
 Asp Leu Pro Glu Gly Ile Thr Val Ala Tyr Thr Ile Pro Lys Lys Gln
     210                 215                 220                
 Glu Asp Ser Val Thr Glu Leu Thr Val Glu Asp Ser Gly Glu Ser Leu
 225                 230                 235                 240
 Glu Asp Leu Met Ala Lys Met Lys Asn Met Xaa Ile Ser Trp Ile Glu
                 245                 250                 255    





      <210> 2895
      <211> 789
      <212> PRT
      <213> Homo sapiens


      <400> 2895
 Ala Gly Gly Ala Arg Leu Arg Pro Ala Arg Gly Arg Pro Pro Arg Leu
   1               5                  10                  15    
 Leu Pro Pro Arg Pro Gly Pro Cys Arg Pro Pro Pro Val Pro Ala Pro
              20                  25                  30        
 Thr Val Asn Glu Arg Arg Ala Pro Pro Arg Ala Gly Trp Glu Arg Arg
          35                  40                  45            
 Ser Asp Ala Gly Leu Ser Arg Gly Ala Arg Pro Ala Glu Met Tyr Gly
      50                  55                  60                
 Val Cys Gly Cys Tyr Gly Ala Leu Arg Pro Arg Tyr Lys Arg Leu Val
  65                  70                  75                  80
 Asp Asn Ile Phe Pro Glu Asp Pro Glu Asp Gly Leu Val Lys Thr Asn
                  85                  90                  95    
 Met Glu Lys Leu Thr Phe Tyr Ala Leu Ser Ala Pro Glu Lys Leu Asp
             100                 105                 110        
 Arg Ile Gly Ala Tyr Leu Ser Glu Arg Leu Ile Arg Asp Val Gly Arg
         115                 120                 125            
 His Arg Tyr Gly Tyr Val Cys Ile Ala Met Glu Ala Leu Asp Gln Leu
     130                 135                 140                
 Leu Met Ala Cys His Cys Gln Ser Ile Asn Leu Phe Val Glu Ser Phe
 145                 150                 155                 160
 Leu Lys Met Val Ala Lys Leu Leu Glu Ser Glu Lys Pro Asn Leu Gln
                 165                 170                 175    
 Ile Leu Gly Thr Asn Ser Phe Val Lys Phe Ala Asn Ile Glu Glu Asp
             180                 185                 190        
 Thr Pro Ser Tyr His Arg Ser Tyr Asp Phe Phe Val Ser Arg Phe Ser
         195                 200                 205            
 Glu Met Cys His Ser Ser His Asp Asp Leu Glu Ile Lys Thr Lys Ile
     210                 215                 220                
 Arg Met Ser Gly Ile Lys Gly Leu Gln Gly Val Val Arg Lys Thr Val
 225                 230                 235                 240
 Asn Asp Glu Leu Gln Ala Asn Ile Trp Asp Pro Gln His Met Asp Lys
                 245                 250                 255    
 Ile Val Pro Ser Leu Leu Phe Asn Leu Gln His Val Glu Glu Ala Glu
             260                 265                 270        
 Ser Arg Ser Pro Ser Pro Leu Gln Ala Pro Glu Lys Glu Lys Glu Ser
         275                 280                 285            
 Pro Ala Glu Leu Ala Glu Arg Cys Leu Arg Glu Leu Leu Gly Arg Ala
     290                 295                 300                
 Ala Phe Gly Asn Ile Lys Asn Ala Ile Lys Pro Val Leu Ile His Leu
 305                 310                 315                 320
 Asp Asn His Ser Leu Trp Glu Pro Lys Val Phe Ala Ile Arg Cys Phe
                 325                 330                 335    
 Lys Ile Ile Met Tyr Ser Ile Gln Pro Gln His Ser His Leu Val Ile
             340                 345                 350        
 Gln Gln Leu Leu Gly His Leu Asp Ala Asn Ser Arg Ser Ala Ala Thr
         355                 360                 365            
 Val Arg Ala Gly Ile Val Glu Val Leu Ser Glu Ala Ala Val Ile Ala
     370                 375                 380                
 Ala Thr Gly Ser Val Gly Pro Thr Val Leu Glu Met Phe Asn Thr Leu
 385                 390                 395                 400
 Leu Arg Gln Leu Arg Leu Ser Ile Asp Tyr Ala Leu Thr Gly Ser Tyr
                 405                 410                 415    
 Asp Gly Ala Val Ser Leu Gly Thr Lys Ile Ile Lys Glu His Glu Glu
             420                 425                 430        
 Arg Met Phe Gln Glu Ala Val Ile Lys Thr Val Gly Ser Phe Ala Ser
         435                 440                 445            
 Thr Leu Pro Thr Tyr Gln Arg Ser Glu Val Ile Leu Phe Ile Met Ser
     450                 455                 460                
 Lys Val Pro Arg Pro Ser Leu His Gln Ala Val Asp Thr Gly Arg Thr
 465                 470                 475                 480
 Gly Glu Asn Arg Asn Arg Leu Thr Gln Ile Met Leu Leu Lys Ser Leu
                 485                 490                 495    
 Leu Gln Val Ser Thr Gly Phe Gln Cys Asn Asn Met Met Ser Ala Leu
             500                 505                 510        
 Pro Ser Asn Phe Leu Asp Arg Leu Leu Ser Thr Ala Leu Met Glu Asp
         515                 520                 525            
 Ala Glu Ile Arg Leu Phe Val Leu Glu Ile Leu Ile Ser Phe Ile Asp
     530                 535                 540                
 Arg His Gly Asn Arg His Lys Phe Ser Thr Ile Ser Thr Leu Ser Asp
 545                 550                 555                 560
 Ile Ser Val Leu Lys Leu Lys Val Asp Lys Cys Ser Arg Gln Asp Thr
                 565                 570                 575    
 Val Phe Met Lys Lys His Ser Gln Gln Leu Tyr Arg His Ile Tyr Leu
             580                 585                 590        
 Ser Cys Lys Glu Glu Thr Asn Val Gln Lys His Tyr Glu Ala Leu Tyr
         595                 600                 605            
 Gly Leu Leu Ala Leu Ile Ser Ile Glu Leu Ala Asn Glu Glu Val Val
     610                 615                 620                
 Val Asp Leu Ile Arg Leu Val Leu Ala Val Gln Asp Val Ala Gln Val
 625                 630                 635                 640
 Asn Glu Glu Asn Leu Pro Val Tyr Asn Arg Cys Ala Leu Tyr Ala Leu
                 645                 650                 655    
 Gly Ala Ala Tyr Leu Asn Leu Ile Ser Gln Leu Thr Thr Val Pro Ala
             660                 665                 670        
 Phe Cys Gln His Ile His Glu Val Ile Glu Thr Arg Lys Lys Glu Ala
         675                 680                 685            
 Pro Tyr Met Leu Pro Glu Asp Val Phe Val Glu Arg Pro Arg Leu Ser
     690                 695                 700                
 Gln Asn Leu Asp Gly Val Val Ile Glu Leu Leu Phe Arg Gln Ser Lys
 705                 710                 715                 720
 Ile Ser Glu Val Leu Gly Gly Ser Gly Tyr Asn Ser Asp Arg Leu Cys
                 725                 730                 735    
 Leu Pro Tyr Ile Pro Gln Leu Thr Asp Glu Asp Arg Leu Ser Lys Arg
             740                 745                 750        
 Arg Ser Ile Gly Glu Thr Ile Ser Leu Gln Val Glu Val Glu Ser Arg
         755                 760                 765            
 Asn Ser Pro Glu Lys Glu Glu Val Ser Val Arg Ala Thr Val Leu Gly
     770                 775                 780                
 Gln Pro His Leu Leu
 785                



      <210> 2896
      <211> 131
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(131)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2896
 Arg Glu Met Gly Phe Arg His Val Gly Gln Thr Gly Leu Glu Leu Leu
   1               5                  10                  15    
 Thr Ser Gly Asp Leu Pro Thr Ser Ala Ser Gln Ser Ala Gly Ile Thr
              20                  25                  30        
 Gly Val Ser His His Thr Trp Pro Lys Thr Leu Phe Val Leu Arg Gln
          35                  40                  45            
 Ser Leu Thr Leu Ser Pro Gly Leu Glu Cys Ser Gly Thr Ile Ser Ala
      50                  55                  60                
 His Cys Ser Pro His Leu Pro Cys Ser Ser Asn Ser Cys Ala Pro Ala
  65                  70                  75                  80
 Ser Arg Val Ala Glu Ser Thr Glu Ala His His Leu Cys Pro Asp Asn
                  85                  90                  95    
 Leu His Ile Ser Ser Arg Glu Gly Ala Ser Pro Cys Trp Pro Gly Cys
             100                 105                 110        
 Ser Xaa Thr Pro Glu Leu Lys Arg Pro Ala His Pro Cys Arg Asp Gln
         115                 120                 125            
 Leu Gly His
     130    



      <210> 2897
      <211> 143
      <212> PRT
      <213> Homo sapiens


      <400> 2897
 Phe Cys Ser Met Ser Ser Gln Lys Trp Ser Trp Gln Ala Gln Pro Leu
   1               5                  10                  15    
 Ser Trp Arg His Trp Ser Gln Gly Pro Val Pro Ser Leu Pro Ala Lys
              20                  25                  30        
 Leu Leu Phe Lys Gly Phe Leu Pro Gly Thr Ala Lys Pro Ala Cys Ser
          35                  40                  45            
 Ala Phe Arg Glu Ala Ala Ala Leu Ala Phe Ile Gln Asp Asn Lys Thr
      50                  55                  60                
 Ala Ile Ser Glu Glu Lys Gly Asn Gly Ser Arg Phe Leu Gly Phe Pro
  65                  70                  75                  80
 Ser Ala Arg Leu Arg Gly Arg Pro Arg Ala Glu Ser Pro Arg Pro Glu
                  85                  90                  95    
 Pro Arg Ala Arg Pro Arg Ala Thr Gln Pro Gly Pro Ala Ala Pro Ala
             100                 105                 110        
 Ala His Ala Thr Pro Pro Pro Gly Pro Ala Pro Ala Pro Tyr Leu Val
         115                 120                 125            
 Ile Arg Gly Ala Ser Gly Gly Arg Gly Asn Val Arg Gly Pro Lys
     130                 135                 140            



      <210> 2898
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 2898
 Asp Leu His Phe Glu Ile Gln Val Leu Leu Glu Ala Leu Arg Gly Leu
   1               5                  10                  15    
 Cys Ser Leu Tyr Pro Lys His Arg Glu Gly Ser Leu Lys Val His Pro
              20                  25                  30        
 Gly His Leu Cys Trp Met Pro Thr Val Thr Arg Pro Gly Thr Pro Pro
          35                  40                  45            
 Ser Gln Ala Ser Thr Gly Ala Gln Glu Leu Pro Gly Gly Glu Lys Lys
      50                  55                  60                
 Thr Cys Arg Trp Glu Lys Lys Lys Lys Thr Phe Pro Gly Ser Ala Gly
  65                  70                  75                  80
 Leu Thr Gly Lys Ser Ile Glu Arg Leu Thr Arg Pro Ala Leu Tyr Leu
                  85                  90                  95    
 Arg Pro Leu Leu Phe Ser Ser Phe Pro Val Arg Val Thr Leu Glu Ala
             100                 105                 110        
 Leu Pro Gly Gly Val Pro Lys Arg Ser Ala Ser Arg Met Pro Val Glu
         115                 120                 125            
 Met Lys Arg Gly Pro Phe
     130                



      <210> 2899
      <211> 77
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(77)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2899
 Lys Arg Gly Thr Glu Arg Lys Thr His Phe Gly Gly Cys Ser Ile Gln
   1               5                  10                  15    
 Phe Ser Asp Ile Ala Ser Gly Lys Asn Ile Leu Pro Gly Leu Cys Phe
              20                  25                  30        
 Leu Thr His Lys Arg Trp Phe Cys Ser Leu Xaa Arg Gln Gly Trp Val
          35                  40                  45            
 Ser Arg Trp Ser His Glu Xaa Gly Cys Thr Arg Cys Trp Arg Leu Gly
      50                  55                  60                
 Lys Phe Leu Trp Val Ala Asp Arg Phe Leu Gly Ser Gly
  65                  70                  75        



      <210> 2900
      <211> 487
      <212> PRT
      <213> Homo sapiens


      <400> 2900
 Met Lys Ala Met Pro Trp Asn Trp Thr Cys Leu Leu Ser His Leu Leu
   1               5                  10                  15    
 Met Val Gly Met Gly Ser Ser Thr Leu Leu Thr Arg Gln Pro Ala Pro
              20                  25                  30        
 Leu Ser Gln Lys Gln Arg Ser Phe Val Thr Phe Arg Gly Glu Pro Ala
          35                  40                  45            
 Glu Gly Phe Asn His Leu Val Val Asp Glu Arg Thr Gly His Ile Tyr
      50                  55                  60                
 Leu Gly Ala Val Asn Arg Ile Tyr Lys Leu Ser Ser Asp Leu Lys Val
  65                  70                  75                  80
 Leu Val Thr His Glu Thr Gly Pro Asp Glu Asp Asn Pro Lys Cys Tyr
                  85                  90                  95    
 Pro Pro Arg Ile Val Gln Thr Cys Asn Glu Pro Leu Thr Thr Thr Asn
             100                 105                 110        
 Asn Val Asn Lys Met Leu Leu Ile Asp Tyr Lys Glu Asn Arg Leu Ile
         115                 120                 125            
 Ala Cys Gly Ser Leu Tyr Gln Gly Ile Cys Lys Leu Leu Arg Leu Glu
     130                 135                 140                
 Asp Leu Phe Lys Leu Gly Glu Pro Tyr His Lys Lys Glu His Tyr Leu
 145                 150                 155                 160
 Ser Gly Val Asn Glu Ser Gly Ser Val Phe Gly Val Ile Val Ser Tyr
                 165                 170                 175    
 Ser Asn Leu Asp Asp Lys Leu Phe Ile Ala Thr Ala Val Asp Gly Lys
             180                 185                 190        
 Pro Glu Tyr Phe Pro Thr Ile Ser Ser Arg Lys Leu Thr Lys Asn Ser
         195                 200                 205            
 Glu Ala Asp Gly Met Phe Ala Tyr Val Phe His Asp Glu Phe Val Ala
     210                 215                 220                
 Ser Met Ile Lys Ile Pro Ser Asp Thr Phe Thr Ile Ile Pro Asp Phe
 225                 230                 235                 240
 Asp Ile Tyr Tyr Val Tyr Gly Phe Ser Ser Gly Asn Phe Val Tyr Phe
                 245                 250                 255    
 Leu Thr Leu Gln Pro Glu Met Val Ser Pro Pro Gly Ser Thr Thr Lys
             260                 265                 270        
 Glu Gln Val Tyr Thr Ser Lys Leu Val Arg Leu Cys Lys Glu Asp Thr
         275                 280                 285            
 Ala Phe Asn Ser Tyr Val Glu Val Pro Ile Gly Cys Glu Arg Ser Gly
     290                 295                 300                
 Val Glu Tyr Arg Leu Leu Gln Ala Ala Tyr Leu Ser Lys Ala Gly Ala
 305                 310                 315                 320
 Val Leu Gly Arg Thr Leu Gly Val His Pro Asp Asp Asp Leu Leu Phe
                 325                 330                 335    
 Thr Val Phe Ser Lys Gly Gln Lys Arg Lys Met Lys Ser Leu Asp Glu
             340                 345                 350        
 Ser Ala Leu Cys Ile Phe Ile Leu Lys Gln Ile Asn Asp Arg Ile Lys
         355                 360                 365            
 Glu Arg Leu Gln Ser Cys Tyr Arg Gly Glu Gly Thr Leu Asp Leu Ala
     370                 375                 380                
 Trp Leu Lys Val Lys Asp Ile Pro Cys Ser Ser Ala Ile Arg Val Asp
 385                 390                 395                 400
 Gly Pro Arg Gly Asn Ala Leu Gln Tyr Glu Thr Val Gln Val Val Asp
                 405                 410                 415    
 Pro Gly Pro Val Leu Arg Asp Met Ala Phe Ser Lys Asp His Glu Gln
             420                 425                 430        
 Leu Tyr Ile Met Ser Glu Arg Gln Ser Gln Glu Leu Cys Pro Pro Gln
         435                 440                 445            
 Glu Leu Asp Asp Ile Phe Ser Cys Cys Gln Thr Pro Arg Ser Pro Asp
     450                 455                 460                
 Phe Ser His Thr Gly Thr His Cys Ala Leu Asp Glu Ala Ala Met Ala
 465                 470                 475                 480
 Trp Glu Trp Ser His Ser Gln
                 485        



      <210> 2901
      <211> 111
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(111)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2901
 Gly Leu Phe Pro Asn Lys Ile Pro Phe Ser Val Leu Glu Ile Arg Thr
   1               5                  10                  15    
 Trp Ala His Leu Ser Gly Arg His His Ser Ala His Cys Thr Ser Cys
              20                  25                  30        
 Ala Trp Pro Gln Val Ala Cys Leu Pro Leu Ala Thr His Pro Ser Cys
          35                  40                  45            
 Thr Cys Thr Phe Cys Ser Leu Gln Ala Pro Gly Arg Pro Gly Gln Ser
      50                  55                  60                
 Pro Leu Ser Pro Arg Arg Ala Cys Gly Pro Glu Asp Leu Pro Pro Pro
  65                  70                  75                  80
 Pro Tyr Val Xaa Asp Leu Ala Pro Ser Leu Gly Pro Ser Leu Gly Pro
                  85                  90                  95    
 Leu Met Ser Gln Ser Gln Pro Arg Arg Thr Pro Pro Leu Arg Gly
             100                 105                 110    



      <210> 2902
      <211> 394
      <212> PRT
      <213> Homo sapiens


      <400> 2902
 Glu Trp Pro Glu Gly Gly Gly Arg Tyr Ser Ser Val Pro Ser Ala Val
   1               5                  10                  15    
 His His Ala Arg Thr Cys Leu Ala Ala Glu Leu Ser Gly Thr Ser Arg
              20                  25                  30        
 Pro Gln Glu Pro Arg Ala Leu Pro Pro Glu Thr Gly Val Ala Thr Ala
          35                  40                  45            
 Glu Ala Glu Lys Ser Asn Gln Pro Ala Ala Ile Ser Lys Pro Asn Gly
      50                  55                  60                
 Gln Gly Ala Pro Leu Gln Arg Arg Ser Pro Arg Leu Ser Pro Ser Pro
  65                  70                  75                  80
 Gly Ala Ala Gln Val Pro Ala Leu Pro Met Gln Asp Met Ser Glu Gly
                  85                  90                  95    
 Ser Ser Ser Pro Ser Pro Pro Gly Gly His Ile Trp Leu Ala Ser Leu
             100                 105                 110        
 Thr Pro Cys Ser Leu Ala Leu Trp Asn Ser Cys Cys Gln Ser Pro Gly
         115                 120                 125            
 Ser Gln Pro Arg Gly Arg Asp Glu Gly Asp Cys Leu Val Arg Ala Thr
     130                 135                 140                
 Glu Pro Ser Ala Thr Gly Pro Asp Pro Arg Arg Thr Arg Leu Cys Ser
 145                 150                 155                 160
 Ile Ser Ala Ser Leu Val Val Arg Asn Thr Pro Asp Pro Gly Ile Ser
                 165                 170                 175    
 Asp Arg Arg Pro Gly Ile Ser Asp Arg Arg Pro Gly Thr Ser Asp Arg
             180                 185                 190        
 Arg Pro Gly Thr Ser Asp Arg Arg Pro Gly Ile Ser Asp Arg Arg Pro
         195                 200                 205            
 Gly Thr Ser Asp Arg Arg Pro Gly Thr Ser Asp Arg Arg Pro Gly Thr
     210                 215                 220                
 Ser Asp Arg Arg Pro Gly Thr Ser Asp Arg Arg Pro Gly Ile Ser Asp
 225                 230                 235                 240
 Arg Arg Pro Gly Thr Ser Asp Arg Arg Pro Gly Ile Ser Asp Arg Arg
                 245                 250                 255    
 Pro Gly Thr Ser Asp Arg Arg Pro Gly Ile Ser Asp Arg Arg Pro Gly
             260                 265                 270        
 Thr Ser Asp Arg Arg Pro Gly Thr Ser Asp Arg Arg Pro Gly Ile Ser
         275                 280                 285            
 Arg Leu Pro Arg Asp Trp Ile Pro Ala Ala Ala Ala Ser Arg Glu Asn
     290                 295                 300                
 Ser Asn Ser Ala Asp Ala Arg Asn Arg Cys Ser Ser Pro Ser Arg Lys
 305                 310                 315                 320
 Cys Gln Thr Pro Thr Ser His Arg Met Arg Gly Ser Ala Gly Ser Val
                 325                 330                 335    
 Gly Ser Ser Ala Gly His Thr Ala Gly Gly Thr Gly Leu Pro Thr Pro
             340                 345                 350        
 Ser Arg Cys Ser Gln Ala Leu Gln Val Phe Pro Ala Val Leu Gly Lys
         355                 360                 365            
 Arg Gly Phe Leu Ser Trp Glu Arg Ser Leu Lys Gln Arg Asp Ile Arg
     370                 375                 380                
 Gly Pro Asp Phe Ser Ser Thr Ala Leu Ile
 385                 390                



      <210> 2903
      <211> 849
      <212> PRT
      <213> Homo sapiens


      <400> 2903
 Met Arg Lys Tyr Asn Ser Leu Val Val Asp Met Arg Lys Val Ser Val
   1               5                  10                  15    
 Val Trp Ile Asp Gln Ala Ser His Asn Ile Pro Leu Ser Gln Ser Gln
              20                  25                  30        
 Ile Gln Ile Arg Pro Phe Asn Ser Val Lys Ala Glu Arg Gly Glu Glu
          35                  40                  45            
 Ala Thr Glu Glu Glu Leu Glu Ala Asn Thr Ala Ser Gly Cys Ala Ser
      50                  55                  60                
 Arg Leu His Ser Tyr Leu Leu Ala Leu His Cys Phe Thr Val Arg Leu
  65                  70                  75                  80
 Cys Gly Val Pro Ser Pro His Leu Phe Ala Ser Ser Thr Ala Ser Leu
                  85                  90                  95    
 Pro Glu Ser Pro Gly Cys Cys Met His Ser Leu Val Thr Lys Ser Pro
             100                 105                 110        
 Cys Gly Asp Pro Leu Glu Pro Asp Asp Ala Thr Leu Phe Lys Gln Asn
         115                 120                 125            
 Leu Phe Tyr Leu Glu Thr Leu Asn Thr Lys Gln Lys Leu Tyr His Lys
     130                 135                 140                
 Lys Ile Phe Arg Thr Ala Met Leu Phe Gln Phe Val Asn Val Leu Leu
 145                 150                 155                 160
 Gln Val Leu Val His Lys Ser His Asp Leu Leu Gln Glu Glu Ile Gly
                 165                 170                 175    
 Ile Ala Ile Tyr Asn Met Ala Ser Val Asp Phe Asp Gly Phe Phe Ala
             180                 185                 190        
 Ala Phe Leu Pro Glu Phe Leu Thr Ser Cys Asp Gly Val Asp Ala Asn
         195                 200                 205            
 Gln Lys Ser Val Leu Gly Arg Asn Phe Lys Met Asp Arg Val Cys Glu
     210                 215                 220                
 Gly Ile Ser Ser Leu Ser Arg Leu Gln Asn Glu Leu Ser Tyr Ile Glu
 225                 230                 235                 240
 Lys Phe Thr Asp Phe Leu Arg Leu Phe Val Ser Val His Leu Arg Arg
                 245                 250                 255    
 Ile Glu Ser Tyr Ser Gln Phe Pro Val Val Glu Phe Leu Thr Leu Leu
             260                 265                 270        
 Phe Lys Tyr Thr Phe His Gln Asp Leu Asp Ile Gln Pro Ser Gln Ala
         275                 280                 285            
 Val Phe Gly Gly Ile Glu Phe Thr Tyr Ile Leu Val Thr Leu Val Ile
     290                 295                 300                
 Leu Gly Thr Gln Arg Val Pro Lys Pro Gly Cys Gly Gln Gly Gly Arg
 305                 310                 315                 320
 Ala Asn Cys Pro Asn Ser Gly Ala Asn Ala Thr Ala Asn Gly Thr Ala
                 325                 330                 335    
 Ala Pro Ala Ala Ala Ala Ala Ala Ala Thr Ala Tyr Gly Glu Arg Pro
             340                 345                 350        
 Thr Trp Arg Arg Ala Asp Thr Ala Gly Arg Pro Ala Thr Asn Ala Ser
         355                 360                 365            
 Ala Ser Gly Phe Pro His Arg Ile Glu Leu Lys Ala Gly Lys Thr Ile
     370                 375                 380                
 Thr Leu Glu Asp Gly Arg Gln Ile Asn Gly Ala Asp Tyr Leu Ala Ala
 385                 390                 395                 400
 Pro Val Pro Gly Lys Ala Leu Ala Ile Phe Gly Asp Thr Gly Pro Cys
                 405                 410                 415    
 Asp Ala Ala Leu Asp Leu Ala Lys Gly Val Asp Val Met Val His Glu
             420                 425                 430        
 Ala Thr Leu Asp Ile Thr Met Glu Ala Lys Ala Asn Ser Arg Gly His
         435                 440                 445            
 Ser Ser Thr Arg Gln Ala Ala Thr Leu Ala Arg Glu Ala Gly Val Gly
     450                 455                 460                
 Lys Leu Ile Ile Thr His Val Ser Ser Arg Tyr Asp Asp Lys Gly Cys
 465                 470                 475                 480
 Gln His Leu Leu Arg Glu Cys Arg Asp Phe Lys Ala Thr Arg Pro Asn
                 485                 490                 495    
 Glu Lys Trp Val Thr Asp Val Thr Glu Phe Ala Val Asn Gly Arg Lys
             500                 505                 510        
 Leu Tyr Leu Ser Pro Val Ile Asp Leu Phe Asn Asn Glu Val Ile Ser
         515                 520                 525            
 Tyr Ser Leu Ser Glu Arg Pro Val Met Asn Met Val Glu Asn Met Leu
     530                 535                 540                
 Asp Gln Ala Phe Lys Lys Leu Asn Pro His Glu His Pro Val Leu His
 545                 550                 555                 560
 Ser Asp Gln Gly Trp Gln Tyr Arg Met Arg Arg Tyr Gln Asn Ile Leu
                 565                 570                 575    
 Lys Glu His Gly Ile Lys Gln Ser Met Ser Arg Lys Gly Asn Cys Leu
             580                 585                 590        
 Asp Asn Ala Val Val Glu Cys Phe Phe Gly Thr Leu Lys Ser Glu Cys
         595                 600                 605            
 Phe Tyr Leu Asp Glu Phe Ser Asn Ile Ser Glu Leu Lys Asp Ala Val
     610                 615                 620                
 Thr Glu Tyr Ile Glu Tyr Tyr Asn Ser Arg Arg Ile Ser Leu Lys Leu
 625                 630                 635                 640
 Lys Ala Leu Ala Val Ala Leu Ala Asn Ile Asp Pro Ile Ile Glu Leu
                 645                 650                 655    
 Thr Ser Cys Ala Asp Ala Cys Lys Arg Thr Ala Leu Val Ala Asn Pro
             660                 665                 670        
 Trp Gln Leu Gly Asn Val Arg Asp Ala Arg Thr Tyr Lys Glu Leu Leu
         675                 680                 685            
 Asp Gln Ile Ala Glu Leu Leu Arg Ile Leu Gly Ser Ala Asp Arg Leu
     690                 695                 700                
 Met Glu Val Ile Arg Glu Glu Leu Glu Leu Val Arg Glu Gln Phe Gly
 705                 710                 715                 720
 Asp Lys Arg Arg Thr Glu Ile Thr Ala Asn Ser Ala Asp Ile Asn Leu
                 725                 730                 735    
 Glu Asp Leu Ile Thr Gln Glu Asp Val Val Val Thr Leu Ser His Gln
             740                 745                 750        
 Gly Tyr Val Lys Tyr Gln Pro Leu Ser Glu Tyr Glu Ala Gln Arg Arg
         755                 760                 765            
 Gly Gly Lys Gly Lys Ser Ala Ala Arg Ile Lys Glu Glu Asp Phe Ile
     770                 775                 780                
 Asp Arg Leu Leu Val Ala Asn Thr His Asp His Ile Leu Cys Phe Ser
 785                 790                 795                 800
 Ser Arg Gly Arg Val Tyr Ser Met Lys Val Tyr Gln Leu Pro Glu Ala
                 805                 810                 815    
 Thr Arg Gly Ala Arg Gly Arg Pro Ile Val Asn Leu Leu Pro Leu Glu
             820                 825                 830        
 Gln Asp Glu Arg Ile Thr Ala Ile Leu Pro Val Thr Glu Leu Gly Ile
         835                 840                 845            
 Leu
    



      <210> 2904
      <211> 157
      <212> PRT
      <213> Homo sapiens


      <400> 2904
 Met Phe Val Ile Ala Phe Leu Ser Pro Leu Ser Leu Ile Phe Leu Ala
   1               5                  10                  15    
 Lys Phe Leu Lys Lys Ala Asp Thr Arg Asp Ser Arg Gln Ala Cys Leu
              20                  25                  30        
 Ala Ala Ser Leu Ala Leu Ala Leu Asn Gly Val Phe Thr Asn Thr Ile
          35                  40                  45            
 Lys Leu Ile Val Gly Arg Pro Arg Pro Asp Phe Phe Tyr Arg Cys Phe
      50                  55                  60                
 Pro Asp Gly Leu Ala His Ser Asp Leu Met Cys Thr Gly Asp Lys Asp
  65                  70                  75                  80
 Val Val Asn Glu Gly Arg Lys Ser Phe Pro Ser Gly His Ser Ser Phe
                  85                  90                  95    
 Ala Phe Ala Gly Leu Ala Phe Ala Ser Phe Tyr Leu Ala Gly Lys Leu
             100                 105                 110        
 His Cys Phe Thr Pro Gln Gly Arg Gly Lys Ser Trp Arg Phe Cys Ala
         115                 120                 125            
 Phe Leu Ser Pro Leu Leu Phe Ala Ala Val Ile Ala Leu Ser Arg Thr
     130                 135                 140                
 Cys Asp Tyr Lys His His Trp Gln Gly Pro Phe Lys Trp
 145                 150                 155        



      <210> 2905
      <211> 767
      <212> PRT
      <213> Homo sapiens


      <400> 2905
 Met Gly Trp Asp Cys Gly Leu Ala Arg Trp Ala Arg Val Gly Leu Arg
   1               5                  10                  15    
 Glu Arg Ala Ala Val Gln Pro Leu Ala Pro Gly Cys Ala Ala Met Ser
              20                  25                  30        
 Phe Ala Phe Pro Pro Phe Ile Pro Gln Gly Tyr Lys Thr Ala Phe Gly
          35                  40                  45            
 Val Gly Thr Asn Lys Ile Val Thr Gln Asp Asn Arg Trp Glu Leu Pro
      50                  55                  60                
 Gly Ala Trp Tyr Phe Pro Arg Ala Ser Ser Gln Ala Arg Glu Met Pro
  65                  70                  75                  80
 Gln Cys Pro Thr Leu Glu Ser Gln Glu Gly Glu Asn Ser Glu Glu Lys
                  85                  90                  95    
 Gly Asp Ser Ser Lys Glu Asp Pro Lys Glu Thr Val Ala Leu Ala Phe
             100                 105                 110        
 Val Arg Glu Asn Pro Gly Ala Gln Asn Gly Leu Gln Asn Ala Gln Gln
         115                 120                 125            
 Gln Gly Lys Lys Lys Arg Lys Lys Lys Arg Leu Gly Leu Lys Ala Gly
     130                 135                 140                
 Glu Trp Gly Ala Met Leu Met Ile Gly Asp Gln Ser Ile Gln Leu Pro
 145                 150                 155                 160
 Ala Phe Leu Ser Ser Ile Val Arg Arg Ala Ala Gln Gln Tyr Gly Phe
                 165                 170                 175    
 Arg Glu Gly Gly Glu Asp Asp Asp Trp Thr Leu Tyr Trp Thr Asp Tyr
             180                 185                 190        
 Ser Val Ser Leu Glu Arg Val Met Glu Met Lys Ser Tyr Gln Lys Ile
         195                 200                 205            
 Asn His Phe Pro Gly Met Ser Glu Ile Cys Arg Lys Asp Leu Leu Ala
     210                 215                 220                
 Arg Asn Met Ser Arg Met Leu Lys Met Phe Pro Lys Asp Phe Arg Phe
 225                 230                 235                 240
 Phe Pro Arg Thr Trp Cys Leu Pro Ala Asp Trp Gly Asp Leu Gln Thr
                 245                 250                 255    
 Tyr Ser Arg Ser Arg Lys Asn Lys Thr Tyr Ile Cys Lys Pro Asp Ser
             260                 265                 270        
 Gly Cys Gln Gly Lys Gly Ile Phe Ile Thr Arg Thr Val Lys Glu Ile
         275                 280                 285            
 Lys Pro Gly Glu Asp Met Ile Cys Gln Leu Tyr Ile Ser Lys Pro Phe
     290                 295                 300                
 Ile Ile Asp Gly Phe Lys Phe Asp Leu Arg Ile Tyr Val Leu Val Thr
 305                 310                 315                 320
 Ser Cys Asp Pro Leu Arg Ile Phe Val Tyr Asn Glu Gly Leu Ala Arg
                 325                 330                 335    
 Phe Ala Thr Thr Ser Tyr Ser Arg Pro Cys Thr Asp Asn Leu Asp Asp
             340                 345                 350        
 Ile Cys Met His Leu Thr Asn Tyr Ser Ile Asn Lys His Ser Ser Asn
         355                 360                 365            
 Phe Ser Arg Asp Ala His Ser Gly Ser Lys Arg Lys Leu Ser Thr Phe
     370                 375                 380                
 Ser Ala Tyr Leu Glu Asp His Ser Tyr Asn Val Glu Gln Ile Trp Arg
 385                 390                 395                 400
 Asp Ile Glu Asp Val Ile Ile Lys Thr Leu Ile Ser Ala His Pro Ile
                 405                 410                 415    
 Ile Arg His Asn Tyr His Thr Cys Phe Pro Asn His Thr Leu Asn Ser
             420                 425                 430        
 Ala Cys Phe Glu Ile Leu Gly Phe Asp Ile Leu Leu Asp His Lys Leu
         435                 440                 445            
 Lys Pro Trp Leu Leu Glu Val Asn His Ser Pro Ser Phe Ser Thr Asp
     450                 455                 460                
 Ser Arg Leu Asp Lys Glu Val Lys Asp Gly Leu Leu Tyr Asp Thr Leu
 465                 470                 475                 480
 Val Leu Ile Asn Leu Glu Ser Cys Asp Lys Lys Lys Val Leu Glu Glu
                 485                 490                 495    
 Glu Arg Gln Arg Gly Gln Phe Leu Gln Gln Cys Cys Ser Arg Glu Met
             500                 505                 510        
 Arg Ile Glu Glu Ala Lys Gly Phe Arg Ala Val Gln Leu Lys Lys Thr
         515                 520                 525            
 Glu Thr Tyr Glu Lys Glu Asn Cys Gly Gly Phe Arg Leu Ile Tyr Pro
     530                 535                 540                
 Ser Leu Asn Ser Glu Lys Tyr Glu Lys Phe Phe Gln Asp Asn Asn Ser
 545                 550                 555                 560
 Leu Phe Gln Asn Thr Val Ala Ser Arg Ala Arg Glu Glu Tyr Ala Arg
                 565                 570                 575    
 Gln Leu Ile Gln Glu Leu Arg Leu Lys Arg Glu Lys Lys Pro Phe Gln
             580                 585                 590        
 Met Lys Lys Lys Val Glu Met Gln Gly Glu Ser Ala Gly Glu Gln Val
         595                 600                 605            
 Arg Lys Lys Gly Met Arg Gly Trp Gln Gln Lys Gln Gln Gln Lys Asp
     610                 615                 620                
 Lys Ala Ala Thr Gln Ala Ser Lys Gln Tyr Ile Gln Pro Leu Thr Leu
 625                 630                 635                 640
 Val Ser Tyr Thr Pro Asp Leu Leu Leu Ser Val Arg Gly Glu Arg Lys
                 645                 650                 655    
 Asn Glu Thr Asp Ser Ser Leu Asn Gln Glu Ala Pro Thr Glu Glu Ala
             660                 665                 670        
 Ser Ser Val Phe Pro Lys Leu Thr Ser Ala Lys Pro Phe Ser Ser Leu
         675                 680                 685            
 Pro Asp Leu Arg Asn Ile Asn Leu Ser Ser Ser Lys Leu Glu Pro Ser
     690                 695                 700                
 Lys Pro Asn Phe Ser Ile Lys Glu Ala Lys Ser Ala Ser Ala Val Asn
 705                 710                 715                 720
 Val Phe Thr Gly Thr Val Val Ser Ile Leu Glu Ala Glu Lys Ser Lys
                 725                 730                 735    
 Ile Lys Val Leu Ala Ser Leu Met Ser Gly Glu Gly Leu Phe Leu Ile
             740                 745                 750        
 Asp Gly Ser Phe Leu Leu Cys Pro His Thr Val Glu Gly Ala Ser
         755                 760                 765        



      <210> 2906
      <211> 505
      <212> PRT
      <213> Homo sapiens


      <400> 2906
 Met Val Asn Thr Glu Arg Gln Leu Asp Trp Ile Glu Arg Cys Gln Val
   1               5                  10                  15    
 Leu Ile Leu Ala Leu Ser Glu Glu Ile Asn Pro Glu Leu Pro Glu Ala
              20                  25                  30        
 Ile Val Met Ala Ser Ser Glu Val Val Thr Arg Gln Asp Asn Ile Asp
          35                  40                  45            
 Ser Pro Gln Glu Pro Pro Pro Thr Pro Leu Phe Ala Ser Arg Pro Val
      50                  55                  60                
 Thr Arg Leu Lys Ser Trp Arg Ala Pro Arg Val Arg Pro Val Gly Pro
  65                  70                  75                  80
 Arg Thr His Pro Val Val Ile Ser Pro Val Pro Glu Cys Ile Ile Ser
                  85                  90                  95    
 Ile Asp Ile Leu Arg Ser Trp Gln Asn Pro His Ile Gly Thr Leu Thr
             100                 105                 110        
 Gly Arg Val Arg Ala Val Met Val Arg Lys Ala Lys Trp Lys Pro Leu
         115                 120                 125            
 Glu Leu Ser Leu Pro Arg Lys Ile Val Asn Gln Lys Gln Tyr Cys Val
     130                 135                 140                
 Pro Gly Gly Ile Val Glu Ile Ser Ala Thr Thr Lys Asp Leu Lys Asp
 145                 150                 155                 160
 Ala Lys Val Val Ile Pro Thr Ile Ser Leu Phe Asn Tyr Pro Ile Trp
                 165                 170                 175    
 Leu Val Gln Lys Asn Asp Gly Ser Trp Arg Met Ala Val Asp Tyr His
             180                 185                 190        
 Lys Leu Thr Gln Gly Val Thr Pro Ile Ala Ala Ala Val Pro Asn Val
         195                 200                 205            
 Ile Ser Leu Leu Glu Gln Ile Asn Thr Ser Ser Gly Thr Trp Tyr Ala
     210                 215                 220                
 Ala Ile Tyr Leu Val Asn Val Phe Phe Ser Ile Pro Val His Lys Ala
 225                 230                 235                 240
 Leu Lys Lys Gln Phe Ala Phe Ser Trp Gln Gly Gln Pro Tyr Thr Phe
                 245                 250                 255    
 Thr Ile Leu Pro Trp Gly His Ile Asn Ser Pro Thr Leu Cys Tyr Asn
             260                 265                 270        
 Leu Ile Trp Arg Glu Leu Asp His Phe Ser Leu Pro Gln Asp Ile Thr
         275                 280                 285            
 Leu Val His Tyr Ile Asp Asp Ile Met Leu Ile Gly Ser Ser Glu Gln
     290                 295                 300                
 Glu Val Ala Asn Thr Leu Asp Leu Leu Glu Lys Ala Leu Gln Gln Val
 305                 310                 315                 320
 Gln Ala Ala Val Gln Ala Ala Leu Pro Leu Gly Pro Tyr Asp Pro Ala
                 325                 330                 335    
 Asp Pro Val Val Leu Glu Val Ser Val Ala Asp Arg Asp Thr Val Trp
             340                 345                 350        
 Ser Leu Cys Ser Cys Cys Tyr Thr Pro Trp Phe Gly Thr Leu Ser His
         355                 360                 365            
 Val Ser Asn Leu Gln Thr Trp Ser Pro Cys Pro Pro Pro Val Ser Pro
     370                 375                 380                
 Val Gly Ser Gln Arg Pro Gln Leu Ser Arg Glu Lys Asn Lys Asn Thr
 385                 390                 395                 400
 Lys Arg Ile His Ser Ile Pro Glu Val Leu Ile Met Lys Pro Tyr Phe
                 405                 410                 415    
 Thr Ala Val Ala Lys Pro Ser Leu Leu Ser His Lys Trp Leu Pro Leu
             420                 425                 430        
 Glu Lys Pro Glu Asn Pro Cys Cys Tyr Ser Ser Asp His Arg Thr Ala
         435                 440                 445            
 Val Pro Asn Leu Leu Leu Tyr Arg Arg Ser Thr Arg Arg Lys Thr Glu
     450                 455                 460                
 Leu Thr Asn Lys Glu Leu Thr Ser Ala His Phe Thr Gly Asp Leu Pro
 465                 470                 475                 480
 Arg Arg Ala Val Trp Val Leu Gly Asp Arg Thr Ala Val Arg Pro Ser
                 485                 490                 495    
 Leu Glu Gln Gly Met Ala Leu Trp Ile
             500                 505



      <210> 2907
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2907
 Lys Gly Ser Thr Glu Ala Phe Ile Ser Gly Thr Ala Gly Trp Gly Thr
   1               5                  10                  15    
 Gly Leu Leu Pro Ser Ser Ala Gly Leu Pro Gly Gly Trp Gly Pro Ala
              20                  25                  30        
 Gly Gly Trp Ala Gly Thr Asp Arg Arg Gly Pro Arg Ala Arg Pro Ile
          35                  40                  45            
 Pro Gln Lys Ser Pro Pro Trp Pro Trp Ser Gly Asp Ala Ala Lys Gly
      50                  55                  60                
 Gln Ser Gly Phe Leu Pro Val Ala Ala Trp Ala Gly Gln Gly Arg Leu
  65                  70                  75                  80
 Pro Gly Gly Gly Ile Ile Val His
                  85            



      <210> 2908
      <211> 315
      <212> PRT
      <213> Homo sapiens


      <400> 2908
 Met Ala Asp Leu Glu Gln Leu Gly Leu Asn Pro Gly Leu Glu Gly Thr
   1               5                  10                  15    
 His His Leu His His Pro Gly His Met Gly Ala Lys Leu Asp Lys Gln
              20                  25                  30        
 His Pro His Asp Arg Val Pro Thr Arg Lys Ser Asp Pro Ala Cys Gly
          35                  40                  45            
 Met Gly Thr Ala Val Ala His His Leu Ala Pro Gly Trp Leu Arg Ala
      50                  55                  60                
 Ala Val Thr Gln Thr Pro Phe Lys Phe Cys Gln Trp Lys Leu Cys Ser
  65                  70                  75                  80
 Cys Val Asn Ile Ala Gly Asp Ser Phe Ser Pro Trp Tyr Gly Gly Ile
                  85                  90                  95    
 Ser Val Ala His Pro Glu Pro Thr Val Thr Ala Ser Pro Thr Thr Gln
             100                 105                 110        
 Gly Ser Ala Leu Pro Pro Gly Glu Glu Asn Pro Ser Glu Val Val Leu
         115                 120                 125            
 Cys Ala Phe Ser Lys Arg Glu Ala Gln Tyr Glu His Ser Leu Arg Pro
     130                 135                 140                
 Leu Lys Glu Asp Arg Thr Val Tyr Arg Val Gly Pro Asn Lys Arg Gly
 145                 150                 155                 160
 Lys Arg Arg Thr Val Leu Lys His Met Gln Trp Lys Leu Ile Lys Gly
                 165                 170                 175    
 Ala Tyr Arg Arg Gly Gln Leu Leu Ala Asn Asn Gln Ala Glu His Lys
             180                 185                 190        
 Val Val Ser Arg Lys Ile Asn Gln Asp Cys Phe Ile Leu Glu Gly Gly
         195                 200                 205            
 Thr Ala Trp Lys Gln His Ala Leu Ser Glu Ser Ser Arg His Ala Leu
     210                 215                 220                
 Ala Gln Phe Phe Ile Val Met His Leu Pro Ala Gln Pro Gly Ala Leu
 225                 230                 235                 240
 Arg Ala Pro Leu Leu Leu Thr Leu Ala Ala Leu Val His Val Gly Val
                 245                 250                 255    
 Gln Ser Arg Gly Ser Arg Ser Arg Phe Leu Gly Cys Leu Glu Pro Ile
             260                 265                 270        
 Glu Arg Ser Phe Leu Gly Val Leu Pro Arg Ser Trp Glu Arg Ser Val
         275                 280                 285            
 Leu Cys Leu Pro Val Asn Ser Leu Gln Gly Ala Cys Leu Arg Leu Pro
     290                 295                 300                
 Ala Ala Ala Asp Ser Ser Ile Phe Lys Arg Ser
 305                 310                 315



      <210> 2909
      <211> 50
      <212> PRT
      <213> Homo sapiens


      <400> 2909
 Thr Arg Arg Gly Gly Cys Pro Glu Glu Lys Val Glu Glu Leu Lys Leu
   1               5                  10                  15    
 Trp Glu Lys Cys Val His Ser Leu Tyr Arg His Ser Ser Ser Ala Leu
              20                  25                  30        
 Asp Leu Gln Lys Ile Pro Gly Ala Ile Tyr Ile Pro Ser Gly Phe Pro
          35                  40                  45            
 Leu Arg
      50



      <210> 2910
      <211> 557
      <212> PRT
      <213> Homo sapiens


      <400> 2910
 Met Gly Gln Val Trp Val Leu Val His Ser Thr Leu Glu Pro Phe His
   1               5                  10                  15    
 Thr Asn Asn Glu Glu Glu Ala Lys Tyr Asn Glu Val Thr Glu Glu Val
              20                  25                  30        
 Thr Glu Gln Val Cys Leu Pro Ala Lys Ala Asn Ala Ala Lys Glu Lys
          35                  40                  45            
 Glu Val His Pro Tyr Pro Ser Ala Pro Leu Asn Tyr Phe Glu Glu Lys
      50                  55                  60                
 Glu Trp Pro Asp Pro Pro Asp Leu Ser Phe Leu Glu Asp Thr Gly Gly
  65                  70                  75                  80
 Asp Pro Ser Leu Thr Ser His Trp Gln Leu Thr Lys Glu Ala Glu Ala
                  85                  90                  95    
 Glu Leu Gln Leu Ile Glu Lys Gln Val His Lys Ala Gln Ile Asn Arg
             100                 105                 110        
 Ile Asp Pro Glu Lys Ile Pro Asp Leu Leu Ile Phe Ser Thr Gln His
         115                 120                 125            
 Ser Pro Thr Gly Val Ile Val Gln Glu Gln Asp Leu Val Glu Trp Phe
     130                 135                 140                
 Phe Leu Pro His Thr Asp Ser Trp Thr Leu Thr Pro Tyr Leu Asp Gln
 145                 150                 155                 160
 Ile Thr Thr Met Ile Gly Ile Gly Arg Thr Arg Ile Val Lys Leu His
                 165                 170                 175    
 Gly Tyr Asp Pro Gly Lys Ile Ile Val Pro Leu Met Lys Ala Gln Ile
             180                 185                 190        
 Gln Gln Ala Phe Ile Asn Ser Leu Thr Trp Gln Thr His Leu Ala Asp
         195                 200                 205            
 Phe Val Gly Ile Leu Asp Asn His Phe Pro Lys Met Lys Leu Phe Gln
     210                 215                 220                
 Phe Leu Lys Leu Thr Asn Cys Ile Leu Pro Lys Ile Thr Lys Phe Lys
 225                 230                 235                 240
 Pro Ile Glu Gly Ala Glu Asn Val Phe Thr Asp Gly Ser Ser Asn Gly
                 245                 250                 255    
 Lys Ala Ser Tyr Phe Gly Ser Lys Arg Lys Val Phe Gln Thr Pro Tyr
             260                 265                 270        
 Thr Ser Ala Gln Lys Val Glu Leu Val Ala Val Ile Glu Leu Leu Thr
         275                 280                 285            
 Ala Phe Asp Met Pro Ile Asn Val Ile Ser Asp Ser Ser Tyr Val Val
     290                 295                 300                
 His Ser Thr Gln Leu Ile Glu Asn Ala Gln Leu Arg Phe His Thr Glu
 305                 310                 315                 320
 Glu Lys Leu Met Thr Leu Phe Thr Gln Leu Gln Thr Ala Val Arg Ser
                 325                 330                 335    
 Arg Met His Arg Phe Tyr Ile Thr His Ile Arg Ala His Thr His Leu
             340                 345                 350        
 Pro Gly Ser Leu Thr Glu Gly Asn Gln Met Ala Asp Arg Leu Val Ala
         355                 360                 365            
 Thr Ala Val Ser Asn Ala Arg His Phe His Ser Leu Thr His Val Asn
     370                 375                 380                
 Ala Ser Gly Leu Lys His Arg Tyr Ser Ile Thr Trp Lys Glu Ala Lys
 385                 390                 395                 400
 Ala Ile Ile Gln Arg Cys Pro Thr Cys Gln Val Val His Ser Ser Ser
                 405                 410                 415    
 Phe Thr Gly Gly Val Asn Pro Arg Gly Leu Glu Pro Asn Ser Leu Trp
             420                 425                 430        
 Glu Met Asp Val Thr His Val Pro Ser Phe Gly Arg Leu Ala Tyr Val
         435                 440                 445            
 His Ala Cys Val Asp Thr Phe Ser His Phe Val Trp Ala Thr Cys Gln
     450                 455                 460                
 Ser Gly Glu Ser Ser Ala Tyr Val Lys Arg His Leu Leu Gln Cys Phe
 465                 470                 475                 480
 Val Val Ile Gly Ile Leu Ala Ser Ile Lys Thr Asp Asn Ala Pro Gly
                 485                 490                 495    
 Tyr Thr Ser Gln Ala Leu Ala Thr Phe Phe Ser Ile Arg Asn Ile Lys
             500                 505                 510        
 His Ile Thr Gly Ile Pro Tyr Asn Ser Gln Gly Gln Ala Ile Val Glu
         515                 520                 525            
 Arg Met Asn Leu Ser Pro Glu Thr Ala Val Ala Lys Ser Lys Lys Lys
     530                 535                 540                
 Gly Gly Lys Gln Gly Leu Arg Gly His Pro Ile Cys Asn
 545                 550                 555        



      <210> 2911
      <211> 138
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(138)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2911
 Glu Thr Gly Arg His Arg Ser Gln Gln Ser Val Ser Ser Pro Pro Val
   1               5                  10                  15    
 Gln Pro Arg Gly Lys Arg Ala Met Tyr His Ser Ala Ala Glu Leu Val
              20                  25                  30        
 Ser Arg Gly Phe Pro Arg Pro Pro Val Gln Ala Pro Ala Glu Pro Ala
          35                  40                  45            
 Gly Ala Ala Glu Gly Val His Ser Gln Pro Ala Ser Arg Gln Glu Ala
      50                  55                  60                
 Gly Ser Thr Glu Val Arg Gly Gln Ala His Arg Phe Val Ser Pro Pro
  65                  70                  75                  80
 Asn Ala Ala Gly Ala Gly Asp Gly Pro Asp Pro Gln Ser Leu Leu Ala
                  85                  90                  95    
 Pro Thr Asn Arg Pro Cys Pro Pro Gly Gly Ile Ser Pro Ala Arg Ser
             100                 105                 110        
 Glu Pro Val Pro Pro Ala Pro Gly Arg Ala Ala Pro Xaa Cys Phe Pro
         115                 120                 125            
 Asp Leu Pro Gly Leu Ala Pro Pro Leu Cys
     130                 135            



      <210> 2912
      <211> 82
      <212> PRT
      <213> Homo sapiens


      <400> 2912
 Met Leu Leu Ile Pro Tyr Phe Leu Glu Trp Lys Lys Leu Trp Pro Leu
   1               5                  10                  15    
 Ala Val Leu Ser Leu Ala Trp Leu Thr Tyr Asp Trp Asn Thr His Ser
              20                  25                  30        
 Gln Gly Gly Arg Arg Ser Ala Trp Val Arg Asn Trp Thr Leu Trp Lys
          35                  40                  45            
 Tyr Phe Arg Asn Tyr Phe Pro Val Lys Leu Val Lys Thr His Asp Leu
      50                  55                  60                
 Ser Pro Lys His Asn Tyr Ile Ile Ala Asn His Pro His Gly Ile Leu
  65                  70                  75                  80
 Ser Phe
        



      <210> 2913
      <211> 58
      <212> PRT
      <213> Homo sapiens


      <400> 2913
 Met Leu Thr Leu Pro Gln Ser Leu Trp Met Leu Thr Arg Arg Thr Ile
   1               5                  10                  15    
 Cys Phe Val Pro Thr Ile Val Ser Cys Arg Gly Leu Leu Pro Ser Asn
              20                  25                  30        
 Pro His His Glu Leu Ala Arg Leu Ile Ser Val Ser Gln His Arg Val
          35                  40                  45            
 Trp Pro His Pro Val Gly Thr Gln Tyr Leu
      50                  55            



      <210> 2914
      <211> 294
      <212> PRT
      <213> Homo sapiens


      <400> 2914
 Ser His Pro Leu Leu Ser Cys Pro Glu Lys Val Ser Ala Lys Leu Arg
   1               5                  10                  15    
 Ala Ala Ala Glu Ala Ala Ala Glu Glu Arg Arg Thr Arg Gly Ala Gly
              20                  25                  30        
 Ser Arg Gly Ile Cys Ala Gly Leu Arg Ser Val Ala Pro Gly Pro Glu
          35                  40                  45            
 Pro Leu Lys Gln Glu Glu Gly Arg Arg Glu Trp Gly Ser Ser Ile Gly
      50                  55                  60                
 Thr Pro Ser Pro Cys Gly Ser Ala Gln Ala Ala Ala Ala Ala Ala Ala
  65                  70                  75                  80
 Glu Glu Ala Thr Glu Lys Ile Pro Ala Leu Arg Pro Ala Leu Leu Trp
                  85                  90                  95    
 Ala Leu Leu Ala Leu Trp Leu Cys Cys Ala Thr Pro Ala His Ala Leu
             100                 105                 110        
 Gln Cys Arg Asp Gly Tyr Glu Pro Cys Val Asn Glu Gly Met Cys Val
         115                 120                 125            
 Thr Tyr His Asn Gly Thr Gly Tyr Cys Lys Cys Pro Glu Gly Phe Leu
     130                 135                 140                
 Gly Glu Tyr Cys Gln His Arg Asp Pro Cys Glu Lys Asn Arg Cys Gln
 145                 150                 155                 160
 Asn Gly Gly Thr Cys Val Ala Gln Ala Met Leu Gly Lys Ala Thr Cys
                 165                 170                 175    
 Arg Cys Ala Ser Gly Phe Thr Gly Glu Asp Cys Gln Tyr Ser Thr Ser
             180                 185                 190        
 His Pro Cys Phe Val Ser Arg Pro Cys Leu Asn Gly Gly Thr Cys His
         195                 200                 205            
 Met Leu Ser Arg Asp Thr Tyr Glu Cys Thr Cys Gln Val Gly Phe Thr
     210                 215                 220                
 Gly Arg Asn Pro Lys Cys Pro Gly Gly Asn Leu Asn Tyr Gln Phe Asn
 225                 230                 235                 240
 Gly Ile Ile Val Val Tyr Ser Gly Gly Ser Val Pro Pro Ser Gly Thr
                 245                 250                 255    
 Lys Thr Ser Lys Pro Ala Glu His Asn Ala Met Gly Thr Gly Ser Lys
             260                 265                 270        
 Asn Phe Ala Ser Gly Thr Leu Trp Val Met Val Ser Gly Ala Thr Ser
         275                 280                 285            
 Thr Ser Thr Ser Thr Leu
     290                



      <210> 2915
      <211> 83
      <212> PRT
      <213> Homo sapiens


      <400> 2915
 Asp Ser Pro Thr Ser Val Ile Trp Ser Ser Ser Thr Gly Lys Tyr Ser
   1               5                  10                  15    
 Pro His Pro Ser Ala Gly Arg Val Val Arg Gly Tyr Cys Pro Arg Arg
              20                  25                  30        
 Val Leu Cys Cys Pro Ser Pro Glu Ala Ala Leu Glu Pro Gly Arg Ala
          35                  40                  45            
 Arg Ala Gln Gly Ile Arg Gly Asp Ser Pro Trp His Gly Pro Thr Cys
      50                  55                  60                
 Thr Gln Pro Gly Arg Lys Thr Val Ile Val Gly Ile Gln Leu Pro Thr
  65                  70                  75                  80
 Gln Ala Ile
            



      <210> 2916
      <211> 298
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(298)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2916
 Val Phe Leu Gln Gln Gly Leu Ala Gln Arg Thr Ile Ile Leu Ile Gly
   1               5                  10                  15    
 Arg Ile Tyr Gln Ser Trp Leu Ala Ile Met Pro Gly Cys Asn His Ser
              20                  25                  30        
 Met Thr Gln Leu His Met Leu Ser Gly Leu Arg Ile Tyr His Asn Lys
          35                  40                  45            
 Ser Ala Pro Val Ile Glu Val Tyr Cys Pro Gln Lys Pro Ile Cys Lys
      50                  55                  60                
 Gln Asn Trp Thr Trp Leu Glu Ile Met Asn Val Phe Val Trp Glu Asp
  65                  70                  75                  80
 Cys Ile Ala Lys Gln Ala Glu Val Leu Cys Asn Asn Ser Tyr Gly Ile
                  85                  90                  95    
 Ile Ile Asp Trp Ser Pro Lys Gly Met Phe Ser Leu Asn Cys Thr Cys
             100                 105                 110        
 Gln Ser Val Cys His Ser His Thr Met Phe Ser Trp Ser Glu Gln Asn
         115                 120                 125            
 Ser Gln Met Val Glu Met Val Arg Asn Thr Ala Arg Val Pro Ile Ile
     130                 135                 140                
 Trp Lys Arg Gly Gly Ile Val Ala Pro Gln Pro Gln Met Ile Trp Ser
 145                 150                 155                 160
 Thr Val Glu Ala Lys His Lys Asp Leu Trp Lys Leu Leu Met Ser Val
                 165                 170                 175    
 Asn Lys Ile Lys Ile Trp Glu Arg Ile Lys Lys His Leu Glu Gly His
             180                 185                 190        
 Ser Thr Asn Leu Phe Leu Asp Met Ala Lys Leu Lys Glu Gln Ile Phe
         195                 200                 205            
 Lys Ala Ser Gln Ala His Leu Thr Leu Met Pro Gly Thr Gly Val Leu
     210                 215                 220                
 Lys Gly Ala Ala Asp Lys Leu Ala Ala Ser Asn Pro Leu Lys Trp Met
 225                 230                 235                 240
 Lys Thr Leu Gly Ser Ser Val Ile Ser Met Met Ile Val Leu Leu Ile
                 245                 250                 255    
 Cys Val Val Cys Leu Cys Val Val Cys Arg Cys Arg Ser Xaa Leu Leu
             260                 265                 270        
 Arg Glu Val Ala His Arg Asp Lys Ala Ala Phe Ala Phe Ile Ala Leu
         275                 280                 285            
 Gln Lys Gln Glu Gly Gly Tyr Ala Gly Glu
     290                 295            



      <210> 2917
      <211> 94
      <212> PRT
      <213> Homo sapiens


      <400> 2917
 Lys Trp Lys Lys Tyr Pro Leu Gly Phe Gln Thr Phe Ser Asn Asn Ser
   1               5                  10                  15    
 Gln Trp Asp Thr Ser Glu Phe Leu Cys Ser Ser Leu Leu Tyr Val Leu
              20                  25                  30        
 Gly Val Ser Ser Gln Asn Ala Val Asn Gln Tyr Ser Ile Glu Arg Ser
          35                  40                  45            
 Ile Val Gly Gly Asp Cys Cys Pro Phe Phe Pro Trp Tyr Val His His
      50                  55                  60                
 Ser Trp Ala Thr Leu Lys Glu Gln Arg Leu Phe Leu Ala Gln Gln Gln
  65                  70                  75                  80
 Gln Glu Asp His Glu Asp Cys Thr Lys Phe Glu Val Pro His
                  85                  90                



      <210> 2918
      <211> 112
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(112)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2918
 Glu Asp Arg Ser Ala Phe Arg Pro Arg Gln Pro His Thr Leu His Pro
   1               5                  10                  15    
 Leu His Ala Arg Ser Leu Ala Pro Arg Ser Pro Thr Pro Pro Ser Pro
              20                  25                  30        
 Pro Ser Pro Asp Thr Gln Leu Gly Leu Ser Gly Pro Thr Ser Gly Pro
          35                  40                  45            
 Glu Ser Ala Pro Thr Ala Pro Gly Asn Pro Ser Trp Arg Ser Ser Arg
      50                  55                  60                
 Trp Gly Ser Ser Ser Pro Cys Ala Ala Ser Ser Thr Xaa Lys Ser Pro
  65                  70                  75                  80
 Tyr Pro Xaa Cys Ser Pro Thr Cys Ala Phe Pro Ser Pro Arg Leu Pro
                  85                  90                  95    
 Phe Cys Arg Ser Ala Tyr Gln Pro Ala Ala Gly Ala Gly Arg Gly Lys
             100                 105                 110        





      <210> 2919
      <211> 79
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(79)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2919
 Val Arg Gln Leu Phe Ser Leu Leu Leu Pro Arg Leu Glu Cys Asn Gly
   1               5                  10                  15    
 Val Ile Ser Ala His Cys Asn Leu Arg Leu Pro Gly Ser Cys Asp Ser
              20                  25                  30        
 Ser Ala Ser Ala Ser Xaa Val Ala Arg Ile Thr Gly Ala Ser Gly Ser
          35                  40                  45            
 Gln Ala Val Val Leu Gln Val Gln Cys Leu Gln Pro Val Gln Pro Gly
      50                  55                  60                
 Glu Leu Leu Arg Val Asp Leu Phe Gln Leu Val Val Leu Gln Arg
  65                  70                  75                



      <210> 2920
      <211> 177
      <212> PRT
      <213> Homo sapiens


      <400> 2920
 Ala Ala Arg Gln Gln His Cys Thr Gln Val Arg Ser Arg Arg Leu Met
   1               5                  10                  15    
 Lys Glu Leu Gln Asp Ile Ala Arg Leu Ser Asp Arg Phe Ile Ser Val
              20                  25                  30        
 Glu Leu Val Asp Glu Ser Leu Phe Asp Trp Asn Val Lys Leu His Gln
          35                  40                  45            
 Val Asp Lys Asp Ser Val Leu Trp Gln Asp Met Lys Glu Thr Asn Thr
      50                  55                  60                
 Glu Phe Ile Leu Leu Asn Leu Thr Phe Pro Asp Asn Phe Pro Phe Ser
  65                  70                  75                  80
 Pro Pro Phe Met Arg Val Leu Ser Pro Arg Leu Glu Asn Gly Tyr Val
                  85                  90                  95    
 Leu Asp Gly Gly Ala Ile Cys Met Glu Leu Leu Thr Pro Arg Gly Trp
             100                 105                 110        
 Ser Ser Ala Tyr Thr Val Glu Ala Val Met Arg Gln Phe Ala Ala Ser
         115                 120                 125            
 Leu Val Lys Gly Gln Gly Arg Ile Cys Arg Lys Ala Gly Lys Ser Lys
     130                 135                 140                
 Lys Ser Phe Ser Arg Lys Glu Ala Glu Ala Thr Phe Lys Ser Leu Val
 145                 150                 155                 160
 Lys Thr His Glu Lys Tyr Gly Trp Gly His Pro Ala Arg Val Pro Asp
                 165                 170                 175    
 Gly
    



      <210> 2921
      <211> 708
      <212> PRT
      <213> Homo sapiens


      <400> 2921
 Ala Gly Gln Thr Pro Gly His Arg Ala Ser Gly Pro Ser Glu Arg Ser
   1               5                  10                  15    
 Pro Ala Pro Arg Ser Arg Leu Gln Pro Gly Gly Glu Ala Ala Thr Arg
              20                  25                  30        
 Thr Glu Pro Ala Thr Pro Gly Arg Arg Ala Gly Pro Gly Ser Ala Thr
          35                  40                  45            
 Met Glu Ala Leu Met Ala Arg Gly Ala Leu Thr Gly Pro Leu Arg Ala
      50                  55                  60                
 Leu Cys Leu Leu Gly Cys Leu Leu Ser His Ala Ala Ala Ala Pro Ser
  65                  70                  75                  80
 Pro Ile Ile Lys Phe Pro Gly Asp Val Ala Pro Lys Thr Asp Lys Glu
                  85                  90                  95    
 Leu Ala Val Gln Tyr Leu Asn Thr Phe Tyr Gly Cys Pro Lys Glu Ser
             100                 105                 110        
 Cys Asn Leu Phe Val Leu Lys Asp Thr Leu Lys Lys Met Gln Lys Phe
         115                 120                 125            
 Phe Gly Leu Pro Gln Thr Gly Asp Leu Asp Gln Asn Thr Ile Glu Thr
     130                 135                 140                
 Met Arg Lys Pro Arg Cys Gly Asn Pro Asp Val Ala Asn Tyr Asn Phe
 145                 150                 155                 160
 Phe Pro Arg Lys Pro Lys Trp Asp Lys Asn Gln Ile Thr Tyr Arg Ile
                 165                 170                 175    
 Ile Gly Tyr Thr Pro Asp Leu Asp Pro Glu Thr Val Asp Asp Ala Phe
             180                 185                 190        
 Ala Arg Ala Phe Gln Val Trp Ser Asp Val Thr Pro Leu Arg Phe Ser
         195                 200                 205            
 Arg Ile His Asp Gly Glu Ala Asp Ile Met Ile Asn Phe Gly Arg Trp
     210                 215                 220                
 Glu His Gly Asp Gly Tyr Pro Phe Asp Gly Lys Asp Gly Leu Leu Ala
 225                 230                 235                 240
 His Ala Phe Ala Pro Gly Thr Gly Val Gly Gly Asp Ser His Phe Asp
                 245                 250                 255    
 Asp Asp Glu Leu Trp Thr Leu Gly Glu Gly Gln Val Val Arg Val Lys
             260                 265                 270        
 Tyr Gly Asn Ala Asp Gly Glu Tyr Cys Lys Phe Pro Phe Leu Phe Asn
         275                 280                 285            
 Gly Lys Glu Tyr Asn Ser Cys Thr Asp Thr Gly Arg Ser Asp Gly Phe
     290                 295                 300                
 Leu Trp Cys Ser Thr Thr Tyr Asn Phe Glu Lys Asp Gly Lys Tyr Gly
 305                 310                 315                 320
 Phe Cys Pro His Glu Ala Leu Phe Thr Met Gly Gly Asn Ala Glu Gly
                 325                 330                 335    
 Gln Pro Cys Lys Phe Pro Phe Arg Phe Gln Gly Thr Ser Tyr Asp Ser
             340                 345                 350        
 Cys Thr Thr Glu Gly Arg Thr Asp Gly Tyr Arg Trp Cys Gly Thr Thr
         355                 360                 365            
 Glu Asp Tyr Asp Arg Asp Lys Lys Tyr Gly Phe Cys Pro Glu Thr Ala
     370                 375                 380                
 Met Ser Thr Val Gly Gly Asn Ser Glu Gly Ala Pro Cys Val Phe Pro
 385                 390                 395                 400
 Phe Thr Phe Leu Gly Asn Lys Tyr Glu Ser Cys Thr Ser Ala Gly Arg
                 405                 410                 415    
 Ser Asp Gly Lys Met Trp Cys Ala Thr Thr Ala Asn Tyr Asp Asp Asp
             420                 425                 430        
 Arg Lys Trp Gly Phe Cys Pro Asp Gln Gly Tyr Ser Leu Phe Leu Val
         435                 440                 445            
 Ala Ala His Glu Phe Gly His Ala Met Gly Leu Glu His Ser Gln Asp
     450                 455                 460                
 Pro Gly Ala Leu Met Ala Pro Ile Tyr Thr Tyr Thr Lys Asn Phe Arg
 465                 470                 475                 480
 Leu Ser Gln Asp Asp Ile Lys Gly Ile Gln Glu Leu Tyr Gly Ala Ser
                 485                 490                 495    
 Pro Asp Ile Asp Leu Gly Thr Gly Pro Thr Pro Thr Leu Gly Pro Val
             500                 505                 510        
 Thr Pro Glu Ile Cys Lys Gln Asp Ile Val Phe Asp Gly Ile Ala Gln
         515                 520                 525            
 Ile Arg Gly Glu Ile Phe Phe Phe Lys Asp Arg Phe Ile Trp Arg Thr
     530                 535                 540                
 Val Thr Pro Arg Asp Lys Pro Met Gly Pro Leu Leu Val Ala Thr Phe
 545                 550                 555                 560
 Trp Pro Glu Leu Pro Glu Lys Ile Asp Ala Val Tyr Glu Ala Pro Gln
                 565                 570                 575    
 Glu Glu Lys Ala Val Phe Phe Ala Gly Asn Glu Tyr Trp Ile Tyr Ser
             580                 585                 590        
 Ala Ser Thr Leu Glu Arg Gly Tyr Pro Lys Pro Leu Thr Ser Leu Gly
         595                 600                 605            
 Leu Pro Pro Asp Val Gln Arg Val Asp Ala Ala Phe Asn Trp Ser Lys
     610                 615                 620                
 Asn Lys Lys Thr Tyr Ile Phe Ala Gly Asp Lys Phe Trp Arg Tyr Asn
 625                 630                 635                 640
 Glu Val Lys Lys Lys Met Asp Pro Gly Phe Pro Lys Leu Ile Ala Asp
                 645                 650                 655    
 Ala Trp Asn Ala Ile Pro Asp Asn Leu Asp Ala Val Val Asp Leu Gln
             660                 665                 670        
 Gly Gly Gly His Ser Tyr Phe Phe Lys Gly Ala Tyr Tyr Leu Lys Leu
         675                 680                 685            
 Glu Asn Gln Ser Leu Lys Ser Val Lys Phe Gly Ser Ile Lys Ser Asp
     690                 695                 700                
 Trp Leu Gly Cys
 705            



      <210> 2922
      <211> 140
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(140)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2922
 Arg Arg Ala Gln Gly Glu Pro Glu Arg Arg Ala Pro Ser Leu Ala Trp
   1               5                  10                  15    
 Thr Cys Arg Asp Pro Ile Pro Thr Arg Glu Glu Leu Ala Leu Thr Ser
              20                  25                  30        
 Thr Thr Thr Ser Cys Ile Ser Ser Leu Ser Ile Val Pro Phe Gln Thr
          35                  40                  45            
 Ile Leu Val Gly Asp Ser Gly Val Gly Lys Thr Ser Leu Leu Val Gln
      50                  55                  60                
 Phe Asp Gln Gly Lys Phe Ile Pro Gly Ser Phe Ser Ala Thr Val Gly
  65                  70                  75                  80
 Ile Gly Phe Thr Asn Lys Val Gly Thr Val Asp Gly Val Arg Glu Lys
                  85                  90                  95    
 Leu Pro Ile Trp Thr Pro Ala Gly Lys Glu Arg Phe Arg Ser Val Thr
             100                 105                 110        
 His Ala Tyr Tyr Arg Asp Ala His Gly Xaa Phe Leu Leu Tyr Asp Pro
         115                 120                 125            
 Asn His Arg Ile Ser Leu Leu Arg Leu Ser Ala Leu
     130                 135                 140



      <210> 2923
      <211> 6
      <212> PRT
      <213> Homo sapiens


      <400> 2923
 Met Trp His Leu Ser Val
   1               5    



      <210> 2924
      <211> 150
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(150)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2924
 Val Arg Ser Asp Met Asn Ser Asn Pro Leu Asp Gly Arg Tyr Arg Ala
   1               5                  10                  15    
 Pro Pro Ala Pro Arg Ala Pro Ala Glu Ala Gly Ala Ser Ser Gln Pro
              20                  25                  30        
 Xaa Ser Pro Pro Ala Ala Gln Ala Ser Gly Lys Glu Gly Gly Glu Asn
          35                  40                  45            
 Asn Ala Pro Leu Phe Gln Xaa Thr Pro Leu Pro Thr Thr Pro Thr Asp
      50                  55                  60                
 Thr Leu Ser Val Pro Pro Arg Ala Pro Val Pro Pro Ser Asp Arg Phe
  65                  70                  75                  80
 Leu Arg Ser Arg Pro Pro Gly Pro Arg Pro Ser Phe Pro Phe Arg Leu
                  85                  90                  95    
 Gln Gly Gly Gly Gly Ala Pro His Xaa Arg Gly Ser Ser Ala Thr Pro
             100                 105                 110        
 Thr Pro Pro Ala Ser Ala Pro Gly Pro Gly Val Arg Ser Leu Pro Arg
         115                 120                 125            
 Pro Arg Trp Trp Thr Pro Ile Arg Leu Lys Lys Pro Trp Gln Lys Ser
     130                 135                 140                
 Ala Asp Pro Ser Leu Gln
 145                 150



      <210> 2925
      <211> 236
      <212> PRT
      <213> Homo sapiens


      <400> 2925
 Gly Ala Arg Phe Ala Cys Leu Cys Ser Thr Thr Pro Ala Pro Met Ala
   1               5                  10                  15    
 Ser Cys Leu Gly Leu Leu Ile Leu Ser Ser Cys Leu Leu Ala Asp Cys
              20                  25                  30        
 Arg Phe Ile Pro Glu Ala Trp Ser Ala Cys Thr Val Thr Cys Gly Val
          35                  40                  45            
 Gly Thr Gln Val Arg Ile Val Arg Cys Gln Val Leu Leu Ser Phe Ser
      50                  55                  60                
 Gln Ser Val Ala Asp Leu Pro Ile Asp Glu Cys Glu Gly Pro Lys Pro
  65                  70                  75                  80
 Ala Ser Gln Arg Ala Cys Tyr Ala Gly Pro Cys Ser Gly Glu Ile Pro
                  85                  90                  95    
 Glu Phe Asn Pro Asp Glu Thr Asp Gly Leu Phe Gly Gly Leu Gln Asp
             100                 105                 110        
 Phe Asp Glu Leu Tyr Asp Trp Glu Tyr Glu Gly Phe Thr Lys Cys Ser
         115                 120                 125            
 Glu Ser Cys Gly Gly Gly Val Gln Glu Ala Val Val Ser Cys Leu Asn
     130                 135                 140                
 Lys Gln Thr Arg Glu Pro Ala Glu Glu Asn Leu Cys Val Thr Ser Arg
 145                 150                 155                 160
 Arg Pro Pro Gln Leu Leu Lys Ser Cys Asn Leu Asp Pro Cys Pro Ala
                 165                 170                 175    
 Ser Ser Leu Val Val Glu Pro Lys Cys Val Gly Lys Gly His Gln Leu
             180                 185                 190        
 Phe Tyr Leu Thr Thr Val Leu Ser Ser Arg Lys Lys Gln Tyr Arg Leu
         195                 200                 205            
 Ser Met Glu Arg Leu Gln Arg Ser Leu Leu Gly Asn Gln Glu Ala Trp
     210                 215                 220                
 Leu Leu Ile Leu Leu Ser Pro Thr Ser Ser Val Ala
 225                 230                 235    



      <210> 2926
      <211> 38
      <212> PRT
      <213> Homo sapiens


      <400> 2926
 Arg Gln Gly Phe His His Val Gly Gln Ala Gly Leu Lys Leu Leu Thr
   1               5                  10                  15    
 Ser Gly Asp Leu Pro Ala Leu Ala Ser Gln Ser Ala Gly Ile Ala Gly
              20                  25                  30        
 Met Thr His Ser Ala Arg
          35            



      <210> 2927
      <211> 104
      <212> PRT
      <213> Homo sapiens


      <400> 2927
 Asn Asp Gln Ser Ala Leu Val Arg Ala Arg Ser Ser Phe Ser Lys Ser
   1               5                  10                  15    
 Val Lys Pro Arg Thr His Gln Phe Phe His Met Phe Asn Ile Gly Pro
              20                  25                  30        
 Ala Arg Asp Gly Pro Pro Pro Pro Ser Pro Ala Pro His Gly Pro Gly
          35                  40                  45            
 Thr Leu Pro Tyr Arg Gly Ser Ser Arg Pro Gly Ser Pro Pro Pro Pro
      50                  55                  60                
 Pro Arg Thr Pro Pro Val Ser Ser Phe Leu Cys His Ser Ser Gly Ala
  65                  70                  75                  80
 Pro Val Thr Arg Arg Asp Ala Ala Ala Gln Ala His Leu Leu Cys Ser
                  85                  90                  95    
 Arg Phe Pro Phe Ser Phe Ile Gly
             100                



      <210> 2928
      <211> 261
      <212> PRT
      <213> Homo sapiens


      <400> 2928
 Met Thr Lys Ile Gln Glu Pro Ser Thr Ser Val Lys Phe Leu Gly Val
   1               5                  10                  15    
 Gln Trp Ser Gly Ala Tyr Gln Asp Ile Pro Ser Lys Val Lys Asp Lys
              20                  25                  30        
 Leu Leu His Leu Ala Pro Pro Thr Thr Thr Lys Glu Ala Tyr Leu Gly
          35                  40                  45            
 Leu Phe Gly Phe Trp Arg Gln His Ile Pro His Leu Gly Thr Glu Gln
      50                  55                  60                
 Glu Lys Thr Leu Gln His Val Gln Ala Ala Val Gln Val Ala Leu Phe
  65                  70                  75                  80
 Leu Glu Pro Tyr Asp Pro Ala Asp Pro Met Val Leu Glu Val Ser Val
                  85                  90                  95    
 Ala Asp Arg Asp Ala Ile Trp Ser Leu Trp Gln Ala Pro Ile Ser Glu
             100                 105                 110        
 Ser Gln Trp Arg Pro Gln Gly Phe Trp Ser Lys Ala Leu Pro Ser Ser
         115                 120                 125            
 Ala Ala Asn Tyr Ser Pro Phe Glu Arg Gln Leu Leu Ala Tyr Tyr Trp
     130                 135                 140                
 Ala Leu Val Glu Thr Glu His Leu Thr Met Gly His Gln Val Thr Lys
 145                 150                 155                 160
 Gln Pro Glu Leu Pro Ile Met Asn Trp Val Leu Ser Asp Pro Ser Ser
                 165                 170                 175    
 His Lys Val Gly Cys Ala Gln Gln His Ser Ile Ile Lys Trp Lys Trp
             180                 185                 190        
 Tyr Ile Cys Asp Arg Ala Arg Ala Gly Pro Glu Gly Thr Thr Thr Pro
         195                 200                 205            
 Val Ile Thr Gln Trp Ala His Glu Gln Ser Gly His Gly Gly Arg Asp
     210                 215                 220                
 Gly Gly Tyr Thr Trp Ala Gln Gln Gln Gly Leu Pro Leu Thr Lys Ala
 225                 230                 235                 240
 Asp Leu Ala Thr Ala Thr Ala Glu Cys Pro Ile Cys Gln Gln Gln Arg
                 245                 250                 255    
 Pro Thr Leu Ser Pro
             260    



      <210> 2929
      <211> 90
      <212> PRT
      <213> Homo sapiens


      <400> 2929
 Met Ala Arg Ala Thr Leu Ser Ala Ala Pro Ser Asn Pro Arg Leu Leu
   1               5                  10                  15    
 Arg Val Ala Leu Leu Leu Leu Leu Leu Val Ala Ala Ser Arg Arg Ala
              20                  25                  30        
 Ala Gly Ala Ser Val Val Thr Glu Leu Arg Cys Gln Cys Leu Gln Thr
          35                  40                  45            
 Leu Gln Gly Ile His Leu Lys Asn Ile Gln Ser Val Asn Ala Thr Leu
      50                  55                  60                
 Lys Asn Gly Lys Lys Ala Cys Leu Asn Pro Ala Ser Pro Met Val Gln
  65                  70                  75                  80
 Lys Ile Ile Glu Lys Ile Leu Asn Asn Pro
                  85                  90



      <210> 2930
      <211> 412
      <212> PRT
      <213> Homo sapiens


      <400> 2930
 Met Leu Ile Gly Ser Ser Glu Gln Glu Val Ala Asn Thr Leu Asp Leu
   1               5                  10                  15    
 Phe Val Arg His Leu His Ala Arg Glu Trp Glu Ile Lys Leu Thr Lys
              20                  25                  30        
 Ile Gln Gly Pro Ser Thr Ser Val Lys Phe Leu Gly Val Gln Trp Tyr
          35                  40                  45            
 Gly Ala Cys Gln Asp Ile Pro Ser Asn Val Lys Asp Thr Leu Leu His
      50                  55                  60                
 Leu Ala Pro Pro Ile Thr Lys Lys Glu Ala Gln Cys Leu Leu Gly Leu
  65                  70                  75                  80
 Phe Gly Phe Trp Arg Gln His Ile Pro His Leu Glu Leu Pro Ile Lys
                  85                  90                  95    
 Asn Trp Val Leu Ser Asp Pro Ser Ser Tyr Lys Val Gly Cys Ala Gln
             100                 105                 110        
 Gln Tyr Ser Ile Ile Lys Trp Lys Trp Tyr Ile Cys Asp Trp Ala Gln
         115                 120                 125            
 Ala Asn Pro Glu Gly Thr Ile Asn Gly Leu Ala Arg Trp Ser Gly Thr
     130                 135                 140                
 Trp Lys Lys His Asn Trp Lys Ile Gly Asp Lys Glu Ile Trp Gly Arg
 145                 150                 155                 160
 Gly Met Trp Met Asp Leu Ser Glu Trp Ser Lys Thr Val Lys Ile Tyr
                 165                 170                 175    
 Val Ser His Val Ser Ala His Gln Gln Met Thr Ser Ala Glu Glu Asp
             180                 185                 190        
 Phe Asn Asn Gln Val Asp Arg Met Thr Arg Ser Met Asp Thr Thr Gln
         195                 200                 205            
 Pro Leu Ser Pro Thr Thr Pro Val Ile Thr Gln Trp Ala His Glu Gln
     210                 215                 220                
 Ser Asp His Gly Gly Arg Asp Gly Asp Tyr Thr Trp Ala Gln Gln His
 225                 230                 235                 240
 Gly Leu Pro Leu Thr Lys Ser Phe Thr Phe Ala Lys Glu Val Trp Gln
                 245                 250                 255    
 Trp Ala His Ala His Gly Ile His Trp Ser Tyr Val Pro His His Pro
             260                 265                 270        
 Glu Ala Ala Gly Leu Ile Glu Arg Trp Asn Gly Leu Leu Lys Ser Gln
         275                 280                 285            
 Leu Lys Cys Gln Leu Gly Asp Asn Thr Leu Gln Gly Trp Gly Lys Val
     290                 295                 300                
 Leu Gln Lys Ala Met Tyr Ala Leu Asn Gln His Pro Ile Tyr Gly Thr
 305                 310                 315                 320
 Val Ser Pro Ile Ala Arg Leu His Gly Ser Arg Asn Gln Gly Glu Glu
                 325                 330                 335    
 Val Glu Val Ala Pro Leu Ile Ile Thr Pro Gly Asp Leu Leu Ala Lys
             340                 345                 350        
 Phe Leu Leu Pro Val Ser Thr Thr Leu His Ser Ala Gly Leu Gly Val
         355                 360                 365            
 Val Tyr Gly Phe Lys Leu Thr Arg Asp Gly Leu Val Met Val Asn Thr
     370                 375                 380                
 Glu Cys Gln Leu Asp Arg Ile Glu Gly Cys Lys Val Leu Phe Leu Gly
 385                 390                 395                 400
 Val Ser Val Arg Val Ser Pro Lys Glu Ile Asn Ile
                 405                 410        



      <210> 2931
      <211> 237
      <212> PRT
      <213> Homo sapiens


      <400> 2931
 Arg Arg Pro Phe Ile Ala Leu Cys Leu Ser Asn Val Ala Phe Met Leu
   1               5                  10                  15    
 Pro Trp Gln Phe Ala Gln Phe Ile Leu Phe Thr Gln Ile Ala Ser Leu
              20                  25                  30        
 Phe Pro Met Tyr Val Val Gly Tyr Ile Glu Pro Ser Lys Phe Gln Lys
          35                  40                  45            
 Ile Ile Tyr Met Asn Met Ile Ser Val Thr Leu Ser Phe Ile Leu Met
      50                  55                  60                
 Phe Gly Asn Ser Met Tyr Leu Ser Ser Tyr Tyr Ser Ser Ser Leu Leu
  65                  70                  75                  80
 Met Thr Trp Ala Ile Ile Leu Lys Arg Asn Glu Ile Gln Lys Leu Gly
                  85                  90                  95    
 Val Ser Lys Leu Asn Cys Trp Leu Ile Gln Gly Ser Ala Trp Trp Cys
             100                 105                 110        
 Gly Thr Ile Ile Leu Lys Phe Leu Thr Ser Lys Ile Leu Gly Val Ser
         115                 120                 125            
 Asp His Ile Cys Leu Ser Asp Leu Ile Ala Ala Gly Ile Leu Arg Tyr
     130                 135                 140                
 Thr Asp Phe Asp Thr Leu Lys Tyr Thr Cys Ser Pro Glu Phe Asp Phe
 145                 150                 155                 160
 Met Glu Lys Ala Thr Leu Leu Ile Tyr Thr Lys Thr Leu Leu Leu Pro
                 165                 170                 175    
 Val Val Met Val Ile Thr Cys Phe Ile Phe Lys Lys Thr Val Gly Asp
             180                 185                 190        
 Ile Ser Arg Val Leu Ala Thr Asn Val Tyr Leu Arg Lys Gln Leu Leu
         195                 200                 205            
 Glu His Ser Glu Leu Ala Phe His Thr Leu Gln Leu Leu Ala Phe Thr
     210                 215                 220                
 Ala Leu Ala Ile Leu Ile Leu Arg Leu Lys Leu Val Leu
 225                 230                 235        



      <210> 2932
      <211> 233
      <212> PRT
      <213> Homo sapiens


      <400> 2932
 Met Arg Phe Val Met Ser Val Thr Met Tyr His Thr Thr Leu Val Gly
   1               5                  10                  15    
 Leu Asp Ile Lys His Leu Asn Leu Glu Ser Gly Lys Val Trp Val Met
              20                  25                  30        
 Gly Lys Ala Ser Lys Glu Pro Arg Leu Pro Ile Gly Arg Asn Ala Val
          35                  40                  45            
 Ala Trp Ile Glu His Trp Leu Asp Leu Arg Asp Leu Phe Gly Ser Lys
      50                  55                  60                
 Asp Asp Ala Leu Phe Leu Ser Lys Leu Gly Lys Arg Ile Ser Ala Arg
  65                  70                  75                  80
 Asn Val Gln Lys Arg Phe Ala Glu Trp Gly Ile Lys Gln Gly Leu Asn
                  85                  90                  95    
 Asn His Val His Pro His Lys Leu Arg His Ser Phe Ala Thr His Met
             100                 105                 110        
 Leu Glu Ser Ser Gly Asp Leu Arg Gly Leu Phe Arg Phe Val Ser Ala
         115                 120                 125            
 Lys Arg His Ala Lys Gly Ser Lys Val Gly Ser Pro Ile Ile Tyr Ala
     130                 135                 140                
 Asp Gln Ile Ile Ile Gly Ala Gly Gln Asn His Pro Ala Arg Trp Arg
 145                 150                 155                 160
 Gly Leu Pro Arg Lys Ser Arg Leu Leu Val Ser Pro Ser Asn Asp Lys
                 165                 170                 175    
 Arg Arg Lys Ala Gly Ala Ala Pro Val Ala Ala Leu Arg His Phe Pro
             180                 185                 190        
 Pro Ile Ser Ile Glu Asn Ala Ile Val Lys Ile Gln Phe Arg Ile Ile
         195                 200                 205            
 Arg Arg Leu Asn His Gln Gln Leu Val Lys Pro Tyr Pro Gln Val Pro
     210                 215                 220                
 Ile Ser Gln Ala Thr Asn Gln Phe Arg
 225                 230            



      <210> 2933
      <211> 823
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(823)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2933
 Met Phe Ala Ile Ile Ser Tyr Ser Ser Leu Ala Ala Val Leu Leu Thr
   1               5                  10                  15    
 Ala Thr Leu Thr Ala Ala Gly Ile Ile Ser Phe Pro Val Ala Leu Cys
              20                  25                  30        
 Leu Val Ile Gly Ala Asn Leu Gly Ser Gly Leu Leu Ala Met Leu Asn
          35                  40                  45            
 Asn Ser Ala Ala Asn Ala Ala Ala Arg Arg Val Ala Leu Gly Ser Leu
      50                  55                  60                
 Leu Phe Lys Leu Val Gly Ser Leu Ile Ile Leu Pro Phe Val His Leu
  65                  70                  75                  80
 Leu Ala Glu Thr Met Gly Lys Leu Ser Leu Pro Lys Ala Glu Leu Val
                  85                  90                  95    
 Ile Tyr Phe His Val Phe Tyr Asn Leu Val Arg Cys Leu Val Met Leu
             100                 105                 110        
 Pro Phe Val Asp Pro Met Ala Arg Phe Cys Lys Thr Ile Ile Arg Asp
         115                 120                 125            
 Glu Pro Glu Leu Asp Thr Gln Leu Arg Pro Lys His Leu Asp Val Ser
     130                 135                 140                
 Ala Leu Asp Thr Pro Thr Leu Ala Leu Ala Asn Ala Ala Arg Glu Thr
 145                 150                 155                 160
 Cys Ala Leu Ala Thr Pro Trp Thr Asp Asp Gly Arg Lys Tyr Ala Tyr
                 165                 170                 175    
 Ser Ala Ala Ser Gly Gly Arg Arg Ser Ala Thr Lys Val Met Val Val
             180                 185                 190        
 Val Thr Asp Gly Glu Ser His Asp Gly Ser Met Leu Lys Ala Val Ile
         195                 200                 205            
 Asp Gln Cys Asn His Asp Asn Ile Leu Arg Phe Gly Ile Ala Val Leu
     210                 215                 220                
 Gly Tyr Leu Asn Arg Asn Ala Leu Asp Thr Lys Asn Leu Ile Lys Glu
 225                 230                 235                 240
 Ile Lys Ala Ile Ala Ser Ile Pro Thr Glu Arg Tyr Phe Phe Asn Val
                 245                 250                 255    
 Ser Asp Glu Ala Ala Leu Leu Glu Lys Ala Gly Thr Leu Gly Glu Gln
             260                 265                 270        
 Ile Phe Ser Ile Glu Asp Met Asp Leu Gly Asp Glu Val Tyr Thr Val
         275                 280                 285            
 Gly Arg Pro His Pro Met Ile Asp Pro Thr Leu Arg Asn Gln Leu Ile
     290                 295                 300                
 Ala Asp Leu Gly Ala Lys Pro Gln Val Arg Val Leu Leu Leu Asp Val
 305                 310                 315                 320
 Val Ile Gly Phe Gly Ala Thr Ala Asp Pro Ala Ala Ser Leu Val Ser
                 325                 330                 335    
 Ala Trp Gln Lys Ala Cys Ala Ala Arg Leu Asp Asn Gln Pro Leu Tyr
             340                 345                 350        
 Ala Ile Ala Thr Val Thr Gly Thr Glu Arg Asp Pro Gln Cys Arg Ser
         355                 360                 365            
 Gln Gln Ile Ala Thr Leu Glu Asp Ala Gly Ile Ala Val Val Ser Ser
     370                 375                 380                
 Leu Pro Glu Ala Thr Leu Leu Ala Ala Ala Leu Ile His Pro Leu Ser
 385                 390                 395                 400
 Pro Ala Ala Gln Gln His Thr Pro Ser Leu Leu Glu Asn Val Ala Val
                 405                 410                 415    
 Ile Asn Ile Gly Leu Arg Ser Phe Ala Leu Glu Leu Gln Ser Ala Ser
             420                 425                 430        
 Lys Pro Val Val His Tyr Gln Trp Ser Pro Val Ala Gly Gln Gly Lys
         435                 440                 445            
 Trp Leu Ala Asn Pro Glu Leu Leu Glu Ala Asp Ala Asp Ala Glu Tyr
     450                 455                 460                
 Ala Ala Val Ile Asp Ile Asp Leu Ala Asp Ile Lys Glu Pro Ile Leu
 465                 470                 475                 480
 Cys Ala Pro Asn Asp Pro Asp Asp Ala Arg Pro Leu Ser Ala Val Gln
                 485                 490                 495    
 Gly Glu Lys Ile Asp Glu Val Phe Ile Gly Ser Cys Met Thr Asn Ile
             500                 505                 510        
 Gly His Phe Arg Ala Ala Gly Lys Leu Leu Asp Ala His Lys Gly Gln
         515                 520                 525            
 Leu Pro Thr Arg Leu Trp Val Ala Pro Pro Thr Arg Met Asp Ala Ala
     530                 535                 540                
 Gln Leu Thr Glu Glu Gly Tyr Tyr Ser Val Phe Gly Lys Ser Gly Ala
 545                 550                 555                 560
 Arg Val Ser Ser Ile Pro Cys Ala Val Pro Cys Val Trp Ala Arg Val
                 565                 570                 575    
 Ala Asp Gly Ala Thr Val Val Ser Thr Ser Thr Arg Asn Phe Pro Asn
             580                 585                 590        
 Arg Leu Gly Thr Gly Ala Asn Val Phe Leu Ala Ser Ala Glu Leu Ala
         595                 600                 605            
 Ala Val Ala Ala Leu Ile Gly Lys Leu Pro Thr Pro Glu Glu Tyr Gln
     610                 615                 620                
 Thr Tyr Val Ala Gln Val Asp Lys Thr Ala Val Asp Thr Tyr Arg Tyr
 625                 630                 635                 640
 Leu Asn Phe Asn Gln Leu Ser Gln Tyr Thr Glu Lys Ala Asp Gly Leu
                 645                 650                 655    
 Leu Lys Pro Arg Phe Arg Pro Trp Gln Arg Lys Ile Leu Asp Thr Leu
             660                 665                 670        
 Ala Thr Tyr His Glu Gln His Arg Asp Glu Pro Gly Pro Gly Arg Glu
         675                 680                 685            
 Arg Leu Arg Arg Met Ala Leu Pro Met Glu Asp Glu Ala Leu Val Leu
     690                 695                 700                
 Leu Leu Ile Glu Lys Met Arg Glu Ser Gly Asp Ile His Ser His His
 705                 710                 715                 720
 Gly Trp Leu His Leu Pro Asp His Lys Ala Gly Xaa Ser Ser Asp Asn
                 725                 730                 735    
 Gly Lys Tyr Gln Arg Leu Phe Tyr Leu Pro Ala Pro Arg Arg Ser Gly
             740                 745                 750        
 Thr Leu Pro Ala Ser Ala Val Cys Gln Ser Ala Pro Gln Gln Leu Ala
         755                 760                 765            
 Ser Ser Ala Glu Ala Arg Lys Thr Phe Ala Pro Val Pro Arg Arg Phe
     770                 775                 780                
 Gly Lys Leu Arg Val Glu Val Glu Thr Thr Val Ala Pro Ser Ala Thr
 785                 790                 795                 800
 Arg Ala His Thr Gln Gly Thr Ala Gln Gly Ile Leu Asp Thr Arg Ala
                 805                 810                 815    
 Pro Leu Leu Pro Lys Thr Leu
             820            



      <210> 2934
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 2934
 Met Pro Gly Leu Leu Asn Trp Ile Thr Gly Ala Ala Leu Pro Leu Thr
   1               5                  10                  15    
 Ala Ser Asp Val Thr Ser Cys Val Ser Gly Tyr Ala Leu Gly Leu Thr
              20                  25                  30        
 Ala Ser Leu Thr Tyr Gly Asn Leu Glu Ala Gln Pro Phe Gln Gly Leu
          35                  40                  45            
 Phe Val Tyr Pro Leu Asp Glu Cys Thr Thr Val Ile Gly Phe Glu Ala
      50                  55                  60                
 Val Ile Ala Asp Arg Val Val Thr Val Gln Ile Lys Asp Lys Ala Lys
  65                  70                  75                  80
 Leu Glu Ser Gly His Phe Asp Ala Ser His Val Arg Ser Pro Thr Val
                  85                  90                  95    
 Thr Gly Asn Ile Leu Gln Asp Gly Val Ser Ile Ala Pro His Ser Cys
             100                 105                 110        
 Thr Pro Gly Lys Val Thr Leu Asp Glu Asp Leu Glu Arg Ile Leu Phe
         115                 120                 125            
 Val Ala Asn Leu Trp Thr Ile Ala Pro Met Tyr Arg Ala Val Trp Asp
     130                 135                 140                





      <210> 2935
      <211> 80
      <212> PRT
      <213> Homo sapiens


      <400> 2935
 Met Gly Ala Val Gln Arg Leu Met Lys Ile Ile Met Leu Asn Tyr Arg
   1               5                  10                  15    
 Leu Val Ala His Phe Leu Val Leu Phe Ala Gln Lys Lys Ala Asn Arg
              20                  25                  30        
 Gln Arg Thr Arg Val His Arg Gly Ser Leu Trp Leu Ser Glu Cys Glu
          35                  40                  45            
 Ser Pro Asn Gly Pro Gly Gly Arg His Thr Glu Pro Ala Glu Gly Arg
      50                  55                  60                
 Gln Ala Arg Gly Arg Thr Pro Gln Gln Gly Phe Ala Val Ser Leu Met
  65                  70                  75                  80





      <210> 2936
      <211> 98
      <212> PRT
      <213> Homo sapiens


      <400> 2936
 Met Asn Lys His Phe Leu Phe Leu Phe Leu Leu Tyr Cys Leu Ile Ala
   1               5                  10                  15    
 Ala Val Thr Ser Leu Gln Cys Ile Thr Cys His Leu Arg Thr Arg Thr
              20                  25                  30        
 Asp Arg Cys Arg Arg Gly Phe Gly Val Cys Thr Ala Gln Lys Gly Glu
          35                  40                  45            
 Ala Cys Met Leu Leu Arg Ile Tyr Gln Arg Asn Thr Leu Gln Ile Ser
      50                  55                  60                
 Tyr Met Val Cys Gln Lys Phe Cys Arg Asp Met Thr Phe Asp Leu Arg
  65                  70                  75                  80
 Asn Arg Thr Tyr Val His Thr Cys Cys Asn Tyr Asn Tyr Cys Asn Phe
                  85                  90                  95    
 Lys Leu
        



      <210> 2937
      <211> 126
      <212> PRT
      <213> Homo sapiens


      <400> 2937
 Met Thr Ala Gly Thr Val Val Ile Thr Gly Gly Ile Leu Ala Thr Val
   1               5                  10                  15    
 Ile Leu Leu Cys Ile Ile Ala Val Leu Cys Tyr Cys Arg Leu Gln Tyr
              20                  25                  30        
 Tyr Cys Cys Lys Lys Ser Gly Thr Glu Val Ala Asp Glu Glu Glu Glu
          35                  40                  45            
 Arg Glu His Asp Leu Pro Thr His Pro Arg Gly Pro Thr Cys Asn Ala
      50                  55                  60                
 Cys Ser Ser Gln Ala Leu Asp Gly Arg Gly Ser Leu Ala Pro Leu Thr
  65                  70                  75                  80
 Ser Glu Pro Cys Ser Gln Pro Cys Gly Val Ala Ala Ser His Cys Thr
                  85                  90                  95    
 Thr Cys Ser Pro Tyr Ser Ser Pro Phe Tyr Ile Arg Thr Ala Asp Met
             100                 105                 110        
 Val Pro Asn Gly Gly Gly Gly Glu Arg Leu Ser Phe Ala Pro
         115                 120                 125    



      <210> 2938
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 2938
 Met Met Pro Thr Asn Leu Ala His Leu Val Phe Trp Gln Ala Leu Leu
   1               5                  10                  15    
 Ala Ser Gly Arg Phe Ser Leu Met Glu His Tyr Pro Pro Asn Val Gln
              20                  25                  30        
 Ser Asn Arg Gly Ile Thr His Tyr Met Leu Pro Arg Gly Tyr Ile Leu
          35                  40                  45            
 Gly Leu Leu Tyr Ser Ser Ala Gly Asn Thr Gly Thr Ser Arg Pro Arg
      50                  55                  60                
 Arg Thr His Tyr Gly Thr
  65                  70



      <210> 2939
      <211> 46
      <212> PRT
      <213> Homo sapiens


      <400> 2939
 Met Asn Arg Val Met Arg Gly Leu Ala Ile Thr Thr Thr Cys Leu Leu
   1               5                  10                  15    
 Ser Met Leu Gln Ala Ile Thr Ile Ser Pro Ser Ile Leu Trp Asn His
              20                  25                  30        
 Ala Ala Val Gln Tyr Val His Gly His Ser Leu Val Gln Ala
          35                  40                  45    



      <210> 2940
      <211> 60
      <212> PRT
      <213> Homo sapiens


      <400> 2940
 Met Pro Gln Trp Leu Ala Leu Gln Arg Gln Gln Ala Leu Leu Thr Leu
   1               5                  10                  15    
 Leu Ser Gly Ala Gly Thr Trp Ala Gly Met Arg Pro Pro Ser Gln Cys
              20                  25                  30        
 Trp Pro Gln Gly Pro Ser Thr Gly Asn Gln Ser Leu Ser His Gly Arg
          35                  40                  45            
 Gly Glu Leu Leu Thr His Ala Val Gly Val Cys Ile
      50                  55                  60



      <210> 2941
      <211> 102
      <212> PRT
      <213> Homo sapiens


      <400> 2941
 Met Leu Met Leu Ile Leu Val Thr Gly Val Ser Ser Leu Arg Asn Met
   1               5                  10                  15    
 Ile Met Cys Asp Tyr Ile Ser Arg Ala Lys Leu Lys Ser Ser His Ile
              20                  25                  30        
 Val Leu Ser Tyr Cys Thr Leu Lys Gln Glu Tyr Asp Asp Ser Arg Gly
          35                  40                  45            
 Val Met Asn Leu Glu Ala Arg Glu Glu Gly Ser Arg Gly Phe Tyr Cys
      50                  55                  60                
 Leu Gly Cys Ile Asp Thr Gly Leu Gln Thr Pro Gly Gly Arg Gly Pro
  65                  70                  75                  80
 Ser Ser Ala Leu Val Thr Ser Val His Leu Ala Cys Glu Glu Tyr Ser
                  85                  90                  95    
 Lys His Ser Phe Val Lys
             100        



      <210> 2942
      <211> 140
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(140)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2942
 Arg Arg Ala Gln Gly Glu Pro Glu Arg Arg Ala Pro Ser Leu Ala Trp
   1               5                  10                  15    
 Thr Cys Arg Asp Pro Ile Pro Thr Arg Glu Glu Leu Ala Leu Thr Ser
              20                  25                  30        
 Thr Thr Thr Ser Cys Ile Ser Ser Leu Ser Ile Val Pro Phe Gln Thr
          35                  40                  45            
 Ile Leu Val Gly Asp Ser Gly Val Gly Lys Thr Ser Leu Leu Val Gln
      50                  55                  60                
 Phe Asp Gln Gly Lys Phe Ile Pro Gly Ser Phe Ser Ala Thr Val Gly
  65                  70                  75                  80
 Ile Gly Phe Thr Asn Lys Val Gly Thr Val Asp Gly Val Arg Glu Lys
                  85                  90                  95    
 Leu Pro Ile Trp Thr Pro Ala Gly Lys Glu Arg Phe Arg Ser Val Thr
             100                 105                 110        
 His Ala Tyr Tyr Arg Asp Ala His Gly Xaa Phe Leu Leu Tyr Asp Pro
         115                 120                 125            
 Asn His Arg Ile Ser Leu Leu Arg Leu Ser Ala Leu
     130                 135                 140



      <210> 2943
      <211> 143
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(143)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2943
 Arg Leu Val Tyr Ala Ser Thr Ala Asn Lys Ile His Phe Xaa Asn Asp
   1               5                  10                  15    
 Asn Asn Pro Gly Lys Asn Thr Asp Thr Val Pro His Cys His Lys Leu
              20                  25                  30        
 Cys Asn Gln Asp Ser His Ile Arg Gly Asn His Arg Gly Gln His Ile
          35                  40                  45            
 His Ser Lys Thr Ala Lys Pro Cys Ser Gly Lys Thr Thr Phe Val Ile
      50                  55                  60                
 Ile Thr Phe Leu Leu Ser Asp Lys His Lys Tyr Lys Leu Ala Pro Leu
  65                  70                  75                  80
 Arg Pro Ala Ala Ala Ser Tyr Ser Ser Pro Phe Thr Arg Lys Val Thr
                  85                  90                  95    
 Cys Leu Thr Arg Ile Thr Glu Pro Ser Xaa Pro Xaa His Thr Ala Ala
             100                 105                 110        
 Thr Leu Arg Ser Asp Gln Arg Ser Gln Thr Cys Ser His Gly Thr Gly
         115                 120                 125            
 Thr Leu Ser Trp Arg Ser Ser Arg Trp Arg Ser Ser Ser Thr Lys
     130                 135                 140            



      <210> 2944
      <211> 351
      <212> PRT
      <213> Homo sapiens


      <400> 2944
 Arg Ala Ser Ser Ala Val Arg Gly Ser Leu Gly Asp Ser Ala Arg Gly
   1               5                  10                  15    
 Arg Arg Arg Arg Ser Ile Val Lys Val Ser Leu His Pro Ala Val Met
              20                  25                  30        
 Ser Lys Ser Glu Ser Pro Lys Glu Pro Glu Gln Leu Arg Lys Leu Phe
          35                  40                  45            
 Ile Gly Gly Leu Ser Phe Glu Thr Thr Asp Glu Ser Leu Arg Ser His
      50                  55                  60                
 Phe Glu Gln Trp Gly Thr Leu Thr Asp Cys Val Val Met Arg Asp Pro
  65                  70                  75                  80
 Asn Thr Lys Arg Ser Arg Gly Phe Gly Phe Val Thr Tyr Ala Thr Val
                  85                  90                  95    
 Glu Glu Val Asp Ala Ala Met Asn Ala Arg Pro His Lys Val Asp Gly
             100                 105                 110        
 Arg Val Val Glu Pro Lys Arg Ala Val Ser Arg Glu Asp Ser Gln Arg
         115                 120                 125            
 Pro Gly Ala His Leu Thr Val Lys Lys Ile Phe Val Gly Gly Ile Lys
     130                 135                 140                
 Glu Asp Thr Glu Glu His His Leu Arg Asp Tyr Phe Glu Gln Tyr Gly
 145                 150                 155                 160
 Lys Ile Glu Val Ile Glu Ile Met Thr Asp Arg Gly Ser Gly Lys Lys
                 165                 170                 175    
 Arg Gly Phe Ala Phe Val Thr Phe Asp Asp His Asp Ser Val Asp Lys
             180                 185                 190        
 Ile Val Ile Gln Lys Tyr His Thr Val Asn Gly His Asn Cys Glu Val
         195                 200                 205            
 Arg Lys Ala Leu Ser Lys Gln Glu Met Ala Ser Ala Ser Ser Ser Gln
     210                 215                 220                
 Arg Gly Arg Ser Gly Ser Gly Asn Phe Gly Gly Gly Arg Gly Gly Gly
 225                 230                 235                 240
 Phe Gly Gly Asn Asp Asn Phe Gly Arg Gly Gly Asn Phe Ser Gly Arg
                 245                 250                 255    
 Gly Gly Phe Gly Gly Ser Arg Gly Gly Gly Gly Tyr Gly Gly Ser Gly
             260                 265                 270        
 Asp Gly Tyr Asn Gly Phe Gly Asn Asp Gly Ser Asn Phe Gly Gly Gly
         275                 280                 285            
 Gly Ser Tyr Asn Asp Phe Gly Asn Tyr Asn Asn Gln Ser Ser Asn Phe
     290                 295                 300                
 Gly Pro Met Lys Gly Gly Asn Phe Gly Gly Arg Ser Ser Gly Pro Tyr
 305                 310                 315                 320
 Gly Gly Gly Gly Gln Tyr Phe Ala Lys Pro Arg Asn Gln Gly Gly Tyr
                 325                 330                 335    
 Gly Gly Ser Ser Ser Ser Ser Ser Tyr Gly Ser Gly Arg Arg Phe
             340                 345                 350    



      <210> 2945
      <211> 141
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(141)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2945
 Val Gln Gln Pro Gly Arg Gly Leu Asp Leu Ser Thr Asp Gly Pro Gly
   1               5                  10                  15    
 Gly Arg Ser Gln Val Gly Leu Ile Trp Ser Cys Cys Cys Leu His Xaa
              20                  25                  30        
 Ala Ala Ser Gly Glu Pro Gly Gly Arg Cys Pro Gly Ser Gly Ala Pro
          35                  40                  45            
 Gly Pro Ala Gly Ser Ala Leu Glu Phe Arg Ala Arg Asp Gly Val Pro
      50                  55                  60                
 Gly Val Gly Gly Pro Ser Trp Glu Ser His Ser Pro Ala Ala Ala Thr
  65                  70                  75                  80
 Pro Pro Pro Ala Glu Cys Arg Gly Pro Gly Pro Thr Pro Ser Pro Ala
                  85                  90                  95    
 Pro Gly Glu Ala Ala Pro Glu Asp Arg Glu Asp Gly Ala Ala Ala Pro
             100                 105                 110        
 Gly Arg Ala Glu Pro Ala Ser Ile Val Ala Pro Ala Asp Gly Ser Gln
         115                 120                 125            
 Gly Gln Val Leu Ala Thr Gln Ala Gly Ala Leu Gly Ala
     130                 135                 140    



      <210> 2946
      <211> 138
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(138)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2946
 Tyr Ile Tyr Gln Ile Ser Gln Thr Ser Gly Lys Leu Xaa Pro Gly Asp
   1               5                  10                  15    
 Lys Ser Val His Ser Glu Leu Val Ser Ser Cys Asn Thr Ser Ile Ile
              20                  25                  30        
 Ser Ser Ser Gly Ile Ser Ser Thr Ser Leu Leu Xaa Leu Arg Arg Leu
          35                  40                  45            
 Phe Ser Ala Ala Ser Ala Asn Ser Ala Ser Ser Val Ala Ser Lys Lys
      50                  55                  60                
 Xaa Ala Ser Ser Met Pro Leu Ser Gln Thr Ala Ser Ala Asp Ala Pro
  65                  70                  75                  80
 Val Asp Ser Leu Leu Gly Asp Gly Leu Xaa Gly Phe Trp Val Ser Leu
                  85                  90                  95    
 Leu Leu Val Ser Ser Ala Ser Ser Val Val Asn Ser Ser Ser Ser Leu
             100                 105                 110        
 Lys Lys Asn Arg Arg His Thr Ser Ala Gly Asn Gly Lys Gln Ser Asp
         115                 120                 125            
 Leu Lys Phe Phe Ala Leu His Thr Gly Ser
     130                 135            



      <210> 2947
      <211> 378
      <212> PRT
      <213> Homo sapiens


      <400> 2947
 Asp Thr Tyr Cys Arg Gly Asp Gln Leu His Ile Leu Leu Val Val Arg
   1               5                  10                  15    
 Asp His Leu Gly Arg Arg Lys Gln Tyr Gly Gly Asp Phe Leu Arg Ala
              20                  25                  30        
 Arg Arg Ser Ser Pro Ala Leu Met Ala Gly Ala Ser Gly Lys Val Thr
          35                  40                  45            
 Asp Phe Asn Asn Gly Thr Tyr Leu Val Ser Phe Thr Leu Phe Trp Glu
      50                  55                  60                
 Gly Gln Val Ser Leu Ser Leu Leu Leu Ile His Pro Ser Glu Gly Val
  65                  70                  75                  80
 Ser Ala Leu Trp Ser Ala Arg Asn Gln Gly Tyr Asp Arg Val Ile Phe
                  85                  90                  95    
 Thr Gly Gln Phe Val Asn Gly Thr Ser Gln Val His Ser Glu Cys Gly
             100                 105                 110        
 Leu Ile Leu Asn Thr Asn Ala Glu Leu Cys Gln Tyr Leu Asp Asn Arg
         115                 120                 125            
 Asp Gln Glu Ser Phe Tyr Trp Val Arg Pro Gln His Met Arg Cys Ala
     130                 135                 140                
 Ala Leu Thr His Met Tyr Ser Lys Asn Lys Lys Val Ser Tyr Leu Ser
 145                 150                 155                 160
 Lys Gln Glu Lys Ser Leu Phe Glu Arg Ser Asn Val Gly Val Glu Ile
                 165                 170                 175    
 Met Glu Lys Phe Asn Thr Ile Ser Val Ser Lys Cys Asn Thr Leu Lys
             180                 185                 190        
 Ser Val Asp Leu His Glu Ser Gly Lys Leu Gln His Gln Leu Ala Val
         195                 200                 205            
 Asp Leu Asp Arg Asn Ile Asn Ile Gln Trp Gln Lys Tyr Cys Tyr Pro
     210                 215                 220                
 Leu Ile Gly Ser Met Thr Tyr Ser Val Lys Glu Met Glu Tyr Leu Thr
 225                 230                 235                 240
 Arg Ala Ile Asp Arg Thr Gly Gly Glu Lys Asn Thr Val Ile Val Ile
                 245                 250                 255    
 Ser Leu Gly Gln His Phe Arg Pro Phe Pro Ile Asp Val Phe Ile Arg
             260                 265                 270        
 Arg Ala Leu Asn Val His Lys Ala Ile Gln His Leu Leu Leu Arg Ser
         275                 280                 285            
 Pro Asp Thr Met Val Ile Ile Lys Thr Glu Asn Ile Arg Glu Met Tyr
     290                 295                 300                
 Asn Asp Ala Glu Arg Phe Ser Asp Phe His Gly Tyr Ile Gln Tyr Leu
 305                 310                 315                 320
 Ile Ile Lys Asp Ile Phe Gln Asp Leu Ser Asp Ile Arg His Val Leu
                 325                 330                 335    
 Lys Tyr Asn Ala Ser Lys Asn Ala Ala Asp Leu Asp Leu Phe Phe Ser
             340                 345                 350        
 Ser Asn Leu Asp Asp Phe Tyr Asn Phe Ser Glu Leu His Lys Gly Arg
         355                 360                 365            
 Ser Lys Ser Pro Leu Met Gln Ile Thr Gln
     370                 375            



      <210> 2948
      <211> 101
      <212> PRT
      <213> Homo sapiens


      <400> 2948
 Gln Leu Ile Gln His Gln Thr Val His Thr Gly Arg Lys Leu Tyr Glu
   1               5                  10                  15    
 Cys Lys Glu Cys Gly Lys Ala Phe Asn Gln Gly Ser Thr Leu Ile Arg
              20                  25                  30        
 His Gln Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Val Cys
          35                  40                  45            
 Gly Lys Ala Phe Arg Val Ser Ser Gln Leu Lys Gln His Gln Arg Ile
      50                  55                  60                
 His Thr Gly Glu Arg Pro Tyr Gln Cys Lys Glu Leu Lys Gly Arg Gly
  65                  70                  75                  80
 Ala Glu Met Leu Ala Val Leu Ala Val Lys Glu Gln Asn Arg Thr Pro
                  85                  90                  95    
 Val Asn Tyr Gly Lys
             100    



      <210> 2949
      <211> 192
      <212> PRT
      <213> Homo sapiens


      <400> 2949
 Met Gly Glu Thr Ala Leu Met Ile Gln Leu Pro Pro Pro Gly Pro Ala
   1               5                  10                  15    
 Leu Gly Thr Trp Gly Leu Trp Asp Leu Gln Phe Lys Thr Asn Thr Thr
              20                  25                  30        
 Ser Thr Asp Thr Asp Pro Arg Ser His Leu Gln Glu Thr Gly Asp Asn
          35                  40                  45            
 Ile Leu Thr Leu Phe Thr Met His Pro Pro Leu Glu Ser Glu Trp Thr
      50                  55                  60                
 Ile Cys Asn Phe Arg Gln Ile Trp Leu Leu Ser Ser Trp Ser Thr Leu
  65                  70                  75                  80
 Glu Thr Arg Ala Gln Pro Leu His Ser Tyr Phe Arg Lys Leu Lys Gly
                  85                  90                  95    
 Arg Gly Thr Ala Ile Ala Gly Ile Val Phe Gly Ile Val Phe Ile Met
             100                 105                 110        
 Gly Val Ile Ala Gly Ile Ala Ile Cys Ile Cys Met Cys Met Lys Asn
         115                 120                 125            
 His Arg Ala Thr Arg Val Gly Ile Leu Arg Thr Thr His Ile Asn Thr
     130                 135                 140                
 Val Ser Ser Tyr Pro Gly Pro Pro Pro Tyr Gly His Asp His Glu Met
 145                 150                 155                 160
 Glu Tyr Cys Ala Asp Leu Pro Pro Pro Tyr Ser Pro Thr Pro Gln Gly
                 165                 170                 175    
 Pro Ala Gln Arg Ser Pro Pro Pro Pro Tyr Pro Gly Asn Ala Arg Lys
             180                 185                 190        





      <210> 2950
      <211> 314
      <212> PRT
      <213> Homo sapiens


      <400> 2950
 Ala Ala Ala Gly Arg Ala Arg Gly Ala Gly Asp Met Phe Arg Arg Lys
   1               5                  10                  15    
 Gln Ser Asn Pro Arg Gln Ile Lys Arg Ser Leu Gly Asp Met Glu Ala
              20                  25                  30        
 Arg Glu Glu Val Gln Leu Val Gly Ala Ser His Met Glu Gln Lys Ala
          35                  40                  45            
 Thr Ala Pro Glu Ala Pro Ser Pro Pro Ser Ala Asp Val Asn Ser Pro
      50                  55                  60                
 Pro Pro Leu Pro Ser Pro Thr Ser Pro Gly Gly Pro Lys Glu Leu Glu
  65                  70                  75                  80
 Gly Gln Glu Pro Glu Pro Arg Pro Thr Glu Glu Glu Pro Gly Ser Pro
                  85                  90                  95    
 Trp Ser Gly Pro Asp Glu Leu Glu Pro Val Val Gln Asp Gly Arg Arg
             100                 105                 110        
 Arg Ile Arg Ala Arg Leu Ser Leu Ala Thr Gly Leu Ser Trp Gly Pro
         115                 120                 125            
 Phe His Gly Ser Val Gln Thr Arg Ala Ser Ser Pro Arg Gln Ala Glu
     130                 135                 140                
 Pro Ser Pro Ala Leu Thr Leu Leu Leu Val Asp Glu Ala Cys Trp Leu
 145                 150                 155                 160
 Arg Thr Leu Pro Gln Ala Leu Thr Glu Ala Glu Ala Asn Thr Glu Ile
                 165                 170                 175    
 His Arg Lys Asp Asp Ala Leu Trp Cys Arg Val Thr Lys Pro Val Pro
             180                 185                 190        
 Ala Gly Gly Leu Leu Ser Val Leu Leu Thr Gly Glu Pro His Ser Thr
         195                 200                 205            
 Pro Gly His Pro Val Lys Lys Glu Pro Ala Glu Pro Thr Cys Pro Ala
     210                 215                 220                
 Pro Ala His Asp Leu Gln Leu Leu Pro Gln Gln Ala Gly Met Ala Ser
 225                 230                 235                 240
 Ile Leu Ala Thr Ala Val Ile Asn Lys Asp Val Phe Pro Cys Lys Asp
                 245                 250                 255    
 Cys Gly Ile Trp Tyr Arg Ser Glu Arg Asn Leu Gln Ala His Leu Leu
             260                 265                 270        
 Tyr Tyr Cys Ala Ser Arg Gln Gly Thr Gly Ser Pro Ala Ala Ala Ala
         275                 280                 285            
 Thr Asp Glu Lys Pro Lys Glu Thr Tyr Pro Asn Glu Arg Val Cys Pro
     290                 295                 300                
 Tyr Pro Gln Ser Arg Lys Ser Cys Pro Gly
 305                 310                



      <210> 2951
      <211> 144
      <212> PRT
      <213> Homo sapiens


      <400> 2951
 Ala Val Cys Arg Thr Ser Ser Asp Val Asp Asp Asn Pro Pro Val Phe
   1               5                  10                  15    
 Asn Gln Leu Ile Tyr Glu Ser Tyr Val Ser Glu Leu Ala Pro Arg Gly
              20                  25                  30        
 His Phe Val Thr Cys Val Gln Ala Ser Asp Ala Asp Ser Ser Asp Phe
          35                  40                  45            
 Asp Arg Leu Glu Tyr Ser Ile Leu Ser Gly Asn Asp Arg Thr Ser Phe
      50                  55                  60                
 Leu Met Asp Ser Lys Ser Gly Val Ile Thr Leu Ser Asn His Arg Lys
  65                  70                  75                  80
 Gln Arg Met Glu Pro Leu Tyr Ser Leu Asn Val Ser Val Ser Asp Gly
                  85                  90                  95    
 Leu Phe Thr Ser Thr Ala Gln Val His Ile Arg Val Leu Gly Ala Asn
             100                 105                 110        
 Leu Tyr Ser Pro Ala Phe Ser Gln Ser Thr Tyr Val Ala Glu Val Arg
         115                 120                 125            
 Glu Asn Val Ala Ala Gly Thr Lys Val Ile His Val Arg Ala Thr Asp
     130                 135                 140                





      <210> 2952
      <211> 67
      <212> PRT
      <213> Homo sapiens


      <400> 2952
 Met Pro Gly Ser Leu Cys Gly Arg Arg Thr Val Cys Trp Leu Leu Gly
   1               5                  10                  15    
 Ser Val Thr Ser Lys Gln Val Leu Thr Phe Asp Leu Arg Lys Phe Ser
              20                  25                  30        
 Arg Ser Ser Arg Leu Gln Glu Asp Gln Glu Arg Ser Leu Gly Phe Arg
          35                  40                  45            
 Pro Phe Thr His Ser Pro Asp Met Met Trp Asp Leu Pro Ala Gln Asp
      50                  55                  60                
 Glu Trp Ser
  65        



      <210> 2953
      <211> 121
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(121)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2953
 Thr Val Leu Cys Leu Thr Leu Thr Ser Cys Ser Phe Arg Gln Ser Leu
   1               5                  10                  15    
 Ala Thr Xaa Ser Phe Gly Gly Met Gly Ser Gly Ser Val His Phe Gly
              20                  25                  30        
 Val Gly Gly Ala Phe Leu Glu Pro Ser Ile His Trp Gly Ser Gly Ser
          35                  40                  45            
 Arg Ser Leu Ser Val Ser Ser Thr His Phe Val Pro Ser Ser Ser Ser
      50                  55                  60                
 Gly Gly Tyr Gly Ser Gly Asp Ala Ser Val Leu Cys Arg Ser Asp Arg
  65                  70                  75                  80
 Leu Leu Thr Gly Thr Lys Ile Thr Thr Gln Asn Ile His Asp Arg Leu
                  85                  90                  95    
 Gly Ser Tyr Leu Asp Lys Val Arg Ala Leu Glu Glu Ala Gly Glu Leu
             100                 105                 110        
 Lys Val Lys Ile Cys Asp Trp Ala Pro
         115                 120    



      <210> 2954
      <211> 223
      <212> PRT
      <213> Homo sapiens


      <400> 2954
 Asn Ser Arg Val Glu Gly Gln Leu Cys Asp Leu Asp Pro Ser Ala His
   1               5                  10                  15    
 Phe Tyr Gly His Cys Gly Glu Gln Leu Glu Cys Arg Leu Asp Thr Gly
              20                  25                  30        
 Gly Asp Leu Ser Arg Gly Glu Val Pro Glu Pro Leu Cys Ala Cys Arg
          35                  40                  45            
 Ser Gln Ser Pro Leu Cys Gly Ser Asp Gly His Thr Tyr Ser Gln Ile
      50                  55                  60                
 Cys Arg Leu Gln Glu Ala Ala Arg Ala Arg Pro Asp Ala Asn Leu Thr
  65                  70                  75                  80
 Val Ala His Pro Gly Pro Cys Glu Ser Gly Pro Gln Ile Val Ser His
                  85                  90                  95    
 Pro Tyr Asp Thr Trp Asn Val Thr Gly Gln Asp Val Ile Phe Gly Cys
             100                 105                 110        
 Glu Val Phe Ala Tyr Pro Met Ala Ser Ile Glu Trp Arg Lys Asp Gly
         115                 120                 125            
 Leu Asp Ile Gln Leu Pro Gly Asp Asp Pro His Ile Ser Val Gln Phe
     130                 135                 140                
 Arg Gly Gly Pro Gln Arg Phe Glu Val Thr Gly Trp Leu Gln Ile Gln
 145                 150                 155                 160
 Ala Val Arg Pro Ser Asp Glu Gly Thr Tyr Arg Cys Leu Ala Arg Asn
                 165                 170                 175    
 Ala Leu Gly Gln Val Glu Ala Pro Ala Ser Leu Thr Val Leu Thr Pro
             180                 185                 190        
 Asp Gln Leu Asn Ser Thr Gly Ile Pro Gln Leu Arg Ser Leu Asn Leu
         195                 200                 205            
 Val Pro Glu Glu Glu Ala Glu Ser Glu Glu Asn Asp Asp Tyr Tyr
     210                 215                 220            



      <210> 2955
      <211> 146
      <212> PRT
      <213> Homo sapiens


      <400> 2955
 Gly Asn Gln Lys Cys Thr Arg Asn Asn His Arg Ile Ser Ser Leu Leu
   1               5                  10                  15    
 Cys Asp Pro Gln Glu Gly Tyr Leu Gln Met Leu Gln Ile Ser Asn Leu
              20                  25                  30        
 Tyr Leu Tyr Asp Ser Val Leu Met Leu Ala Asn Ala Phe His Arg Lys
          35                  40                  45            
 Leu Glu Asp Arg Lys Trp His Asn Met Ala Ser Leu Asn Cys Ile Arg
      50                  55                  60                
 Lys Ser Thr Lys Pro Trp Asn Gly Gly Arg Ser Met Leu Asp Thr Ile
  65                  70                  75                  80
 Lys Lys Gly His Ile Thr Gly Leu Thr Gly Val Met Glu Phe Arg Glu
                  85                  90                  95    
 Asp Ser Ser Asn Pro Tyr Val Gln Phe Glu Ile Leu Gly Thr Thr Tyr
             100                 105                 110        
 Ser Glu Thr Leu Glu Glu Pro Phe Val Met Val Ala Glu Asn Ile Leu
         115                 120                 125            
 Gly Gln Pro Lys Arg Tyr Lys Gly Phe Ser Ile Asp Val Leu Asp Ala
     130                 135                 140                
 Leu Ala
 145    



      <210> 2956
      <211> 124
      <212> PRT
      <213> Homo sapiens


      <400> 2956
 Gly Ser Gly Asp Ala Gly Gly Gln His Arg Ala Arg Cys Pro Ser Gly
   1               5                  10                  15    
 Arg Ala Gly Asn Trp Asp Trp His Pro Pro Ala Met Glu Glu Pro Gly
              20                  25                  30        
 Pro Pro Gly Gly Leu Ser Gln Asp Gln Val Glu Arg Cys Met Gly Ala
          35                  40                  45            
 Met Gln Glu Gly Met Gln Met Val Lys Leu Arg Gly Gly Ser Lys Gly
      50                  55                  60                
 Leu Val Arg Phe Tyr Tyr Leu Asp Glu His Arg Ser Cys Ile Arg Trp
  65                  70                  75                  80
 Arg Pro Ser Arg Lys Asn Glu Lys Ala Glu Ile Ser Ile Asp Ser Ile
                  85                  90                  95    
 Gln Glu Val Ser Glu Gly Arg Gln Ser Glu Val Leu Gln Arg Tyr Pro
             100                 105                 110        
 Asp Gly Ser Phe Asp Pro Asn Cys Cys Cys Ser Ile
         115                 120                



      <210> 2957
      <211> 172
      <212> PRT
      <213> Homo sapiens


      <400> 2957
 Lys Glu Leu Ser Ala Val Ser Ala Gly Ile Pro His Ser Cys Gly Ser
   1               5                  10                  15    
 Gln Gly Cys Gly Gly Gly Ser Val Ala Ala Cys Val Pro Ala Ala Pro
              20                  25                  30        
 Ala Ala Ala Gly Leu Cys Ser Gly Arg Ala Gln Lys Val Pro Pro Pro
          35                  40                  45            
 Pro Ser Leu Ala Gly Trp Pro Pro Gly Val Asn Ala Pro Pro Pro Pro
      50                  55                  60                
 Val Cys Ser Ser Val Arg Leu His Val Cys Gln Ser Asp Arg Leu Trp
  65                  70                  75                  80
 Val Arg Leu Ala Ala Arg Arg Gly Ile Leu Ala Leu Leu Arg Ser Ala
                  85                  90                  95    
 Leu Lys Ala Ala Thr Leu Ala Gly Cys Gln Ser Val Arg Trp Ser Val
             100                 105                 110        
 Arg Pro Ser Glu Ser Leu Arg Pro Thr Ser Asn Ala Ala Ser Leu Phe
         115                 120                 125            
 Arg Ser Ser Val Pro Thr Val Leu Ser His Ser Val Pro Leu Ala Ala
     130                 135                 140                
 Ser Leu Gly Lys Arg Arg Ala Cys Gly Gly Arg Glu His Ala Ser Val
 145                 150                 155                 160
 Ala Val Tyr Leu Ser Val Cys Leu Ser Leu Pro Thr
                 165                 170        



      <210> 2958
      <211> 421
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(421)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2958
 Pro Pro Thr Pro Thr Ala Glu Thr Leu Thr Ser Glu Asp Ala Gln Pro
   1               5                  10                  15    
 Gly Ser Pro Leu Ala Thr Gly Thr Asp Gln Val Ser Leu Asp Lys Pro
              20                  25                  30        
 Leu Ser Ser Ala Ala His Leu Asp Asp Ala Ala Lys Met Pro Ser Ala
          35                  40                  45            
 Ser Ser Gly Glu Glu Ala Asp Ala Gly Ser Leu Leu Pro Thr Thr Asn
      50                  55                  60                
 Glu Leu Ser Gln Ala Leu Ala Gly Ala Asp Ser Leu Asp Ser Pro Pro
  65                  70                  75                  80
 Arg Pro Leu Glu Arg Ser Val Gly Gln Leu Pro Ser Pro Pro Leu Leu
                  85                  90                  95    
 Pro Thr Pro Pro Pro Lys Ala Ser Ser Lys Thr Lys Lys Met Ser Gln
             100                 105                 110        
 Ala Lys Pro His Ser Ser Lys Pro Pro Ala Xaa Arg Val Pro Thr Leu
         115                 120                 125            
 Pro Leu Arg Gly Gln Leu Ser Thr Pro Thr Gly Ser Pro His Leu Thr
     130                 135                 140                
 Thr Val His Arg Pro Leu Pro Pro Ser Arg Val Ile Glu Glu Leu His
 145                 150                 155                 160
 Arg Ala Leu Ala Thr Lys His Arg Gln Asp Ser Phe Gln Gly Arg Glu
                 165                 170                 175    
 Ser Lys Gly Ser Pro Lys Lys Arg Leu Asp Val Arg Leu Ser Arg Thr
             180                 185                 190        
 Ser Ser Val Glu Arg Gly Lys Glu Arg Glu Glu Ala Trp Ser Phe Asp
         195                 200                 205            
 Gly Ala Leu Glu Asn Lys Arg Thr Ala Ala Lys Glu Ser Glu Glu Asn
     210                 215                 220                
 Lys Glu Asn Leu Ile Ile Asn Ser Glu Leu Lys Asp Asp Leu Leu Leu
 225                 230                 235                 240
 Tyr Gln Asp Glu Glu Ala Leu Asn Asp Ser Ile Ile Ser Gly Thr Leu
                 245                 250                 255    
 Pro Arg Lys Cys Lys Lys Glu Leu Leu Ala Val Lys Leu Arg Asn Arg
             260                 265                 270        
 Pro Ser Lys Gln Glu Leu Glu Asp Arg Asn Ile Phe Pro Arg Arg Thr
         275                 280                 285            
 Asp Glu Glu Arg Gln Glu Ile Arg Gln Gln Ile Glu Met Lys Leu Ser
     290                 295                 300                
 Lys Arg Leu Ser Gln Arg Pro Ala Val Glu Glu Leu Glu Arg Arg Asn
 305                 310                 315                 320
 Ile Leu Lys Gln Arg Asn Asp Gln Thr Glu Gln Glu Glu Arg Arg Glu
                 325                 330                 335    
 Ile Lys Gln Arg Leu Thr Arg Lys Leu Asn Gln Arg Pro Thr Val Asp
             340                 345                 350        
 Glu Leu Arg Asp Arg Lys Ile Leu Ile Arg Phe Ser Asp Tyr Val Glu
         355                 360                 365            
 Val Ala Lys Ala Gln Asp Tyr Asp Arg Arg Ala Asp Lys Pro Trp Thr
     370                 375                 380                
 Arg Leu Ser Ala Ala Asp Lys Ala Ala Ile Arg Lys Glu Leu Asn Glu
 385                 390                 395                 400
 Tyr Lys Ser Asn Glu Met Glu Val His Ala Ser Ser Lys His Leu Thr
                 405                 410                 415    
 Arg Phe His Arg Pro
             420    



      <210> 2959
      <211> 298
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(298)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2959
 Val Phe Leu Gln Gln Gly Leu Ala Gln Arg Thr Ile Ile Leu Ile Gly
   1               5                  10                  15    
 Arg Ile Tyr Gln Ser Trp Leu Ala Ile Met Pro Gly Cys Asn His Ser
              20                  25                  30        
 Met Thr Gln Leu His Met Leu Ser Gly Leu Arg Ile Tyr His Asn Lys
          35                  40                  45            
 Ser Ala Pro Val Ile Glu Val Tyr Cys Pro Gln Lys Pro Ile Cys Lys
      50                  55                  60                
 Gln Asn Trp Thr Trp Leu Glu Ile Met Asn Val Phe Val Trp Glu Asp
  65                  70                  75                  80
 Cys Ile Ala Lys Gln Ala Glu Val Leu Cys Asn Asn Ser Tyr Gly Ile
                  85                  90                  95    
 Ile Ile Asp Trp Ser Pro Lys Gly Met Phe Ser Leu Asn Cys Thr Cys
             100                 105                 110        
 Gln Ser Val Cys His Ser His Thr Met Phe Ser Trp Ser Glu Gln Asn
         115                 120                 125            
 Ser Gln Met Val Glu Met Val Arg Asn Thr Ala Arg Val Pro Ile Ile
     130                 135                 140                
 Trp Lys Arg Gly Gly Ile Val Ala Pro Gln Pro Gln Met Ile Trp Ser
 145                 150                 155                 160
 Thr Val Glu Ala Lys His Lys Asp Leu Trp Lys Leu Leu Met Ser Val
                 165                 170                 175    
 Asn Lys Ile Lys Ile Trp Glu Arg Ile Lys Lys His Leu Glu Gly His
             180                 185                 190        
 Ser Thr Asn Leu Phe Leu Asp Met Ala Lys Leu Lys Glu Gln Ile Phe
         195                 200                 205            
 Lys Ala Ser Gln Ala His Leu Thr Leu Met Pro Gly Thr Gly Val Leu
     210                 215                 220                
 Lys Gly Ala Ala Asp Lys Leu Ala Ala Ser Asn Pro Leu Lys Trp Met
 225                 230                 235                 240
 Lys Thr Leu Gly Ser Ser Val Ile Ser Met Met Ile Val Leu Leu Ile
                 245                 250                 255    
 Cys Val Val Cys Leu Cys Val Val Cys Arg Cys Arg Ser Xaa Leu Leu
             260                 265                 270        
 Arg Glu Val Ala His Arg Asp Lys Ala Ala Phe Ala Phe Ile Ala Leu
         275                 280                 285            
 Gln Lys Gln Glu Gly Gly Tyr Ala Gly Glu
     290                 295            



      <210> 2960
      <211> 70
      <212> PRT
      <213> Homo sapiens


      <400> 2960
 Met Ile Ile Ala Ile Gly Gly Val Ile Val Ala Ser Gly Leu Val Phe
   1               5                  10                  15    
 Ile Val Leu Leu Met Ile Arg Tyr Lys Val Tyr Gly Asp Gly Asp Ser
              20                  25                  30        
 Arg Arg Val Lys Gly Ser Arg Ala Leu Pro Arg Val Arg His Val Cys
          35                  40                  45            
 Ser Gln Thr Asn Gly Ala Gly Thr Gly Ala Glu Gln Ala Pro Ala Leu
      50                  55                  60                
 Pro Ala Gln Asp His Tyr
  65                  70



      <210> 2961
      <211> 287
      <212> PRT
      <213> Homo sapiens


      <400> 2961
 Glu Leu Asn Leu Gln Asp Phe Ser His Leu Asp His Arg Asp Leu Ile
   1               5                  10                  15    
 Pro Ile Ile Ala Ala Leu Glu Tyr Asn Gln Trp Phe Thr Lys Leu Ser
              20                  25                  30        
 Ser Lys Asp Leu Lys Leu Ser Thr Asp Val Cys Glu Gln Ile Leu Arg
          35                  40                  45            
 Val Val Ser Arg Ser Asn Arg Leu Glu Glu Leu Val Leu Glu Asn Ala
      50                  55                  60                
 Gly Leu Arg Thr Asp Phe Ala Gln Lys Leu Ala Ser Ala Leu Ala His
  65                  70                  75                  80
 Asn Pro Asn Ser Gly Leu His Thr Ile Asn Leu Ala Gly Asn Pro Leu
                  85                  90                  95    
 Glu Asp Arg Gly Val Ser Ser Leu Ser Ile Gln Phe Ala Lys Leu Pro
             100                 105                 110        
 Lys Gly Leu Lys His Leu Ile Leu Ser Lys Thr His Tyr Tyr Pro Lys
         115                 120                 125            
 Ala Val Asn Ser Leu Ser Gln Ser Leu Ser Ala Asn Pro Leu Thr Ala
     130                 135                 140                
 Ser Thr Leu Val His Leu Asp Leu Ser Gly Asn Val Leu Arg Gly Asp
 145                 150                 155                 160
 Asp Leu Ser His Met Tyr Asn Phe Leu Ala Gln Pro Asn Ala Ile Val
                 165                 170                 175    
 His Leu Asp Leu Ser Asn Thr Glu Cys Ser Leu Asp Met Val Trp Gly
             180                 185                 190        
 Ala Leu Leu Arg Gly Cys Leu Gln Tyr Leu Ala Val Leu Asn Leu Ser
         195                 200                 205            
 Arg Thr Val Phe Ser His Arg Lys Gly Lys Glu Val Pro Pro Ser Phe
     210                 215                 220                
 Lys Gln Phe Phe Ser Ser Ser Leu Ala Leu Met His Ile Asn Leu Ser
 225                 230                 235                 240
 Gly Thr Lys Leu Ser Pro Glu Pro Leu Lys Ala Leu Leu Leu Gly Leu
                 245                 250                 255    
 Ala Cys Asn His Asn Leu Lys Gly Val Ser Leu Asp Leu Ser Asn Cys
             260                 265                 270        
 Glu Leu Arg Ser Gly Gly Ala Gln Val Leu Glu Gly Cys Ile Gly
         275                 280                 285        



      <210> 2962
      <211> 125
      <212> PRT
      <213> Homo sapiens


      <400> 2962
 Thr Gln Ala Phe Glu Gln Glu Val Gly Asn Pro Leu Cys Ile Pro Ser
   1               5                  10                  15    
 His Cys Met Gly Ala Val Phe Ile Leu Leu Asn Leu Ala Thr Ala His
              20                  25                  30        
 Ser Ser Gly Leu Cys Leu Leu Gln Leu Glu Leu Ser Phe Arg Ser Leu
          35                  40                  45            
 Ser Thr Thr Ala Val His Cys Cys Pro Arg Pro Thr Ile Asp Phe His
      50                  55                  60                
 Pro Leu Gly Ser Ser Arg Val Ser Ala Val Leu Leu Ile Gln Gln Arg
  65                  70                  75                  80
 Cys Pro Leu Pro Leu Pro Ile Gly Leu Glu Ala Asp His Cys Ser Cys
                  85                  90                  95    
 Met Ala Lys Gly Pro Gly Phe Ile Leu Ile Glu Leu Asn Thr Ser His
             100                 105                 110        
 Trp Val Pro Gln Phe Ser Ser Val Thr His Asp Phe Tyr
         115                 120                 125



      <210> 2963
      <211> 127
      <212> PRT
      <213> Homo sapiens


      <400> 2963
 Asn Thr Met Val Ala His His Ile Val Glu Asn Thr Tyr Phe Cys Pro
   1               5                  10                  15    
 Val Leu Ala Thr Gly Leu Ser Gly Leu Tyr Ser Ser Leu Pro Thr Lys
              20                  25                  30        
 Leu Glu Glu Lys Gly Glu Glu Trp His Cys Leu Leu Lys Asp Asp Trp
          35                  40                  45            
 Leu Leu Leu Pro Ser Leu Val Gln Phe Met Asn Ser Leu Glu Phe Cys
      50                  55                  60                
 Asn Ala Val Ile Gln Val Ala His Pro Leu Ile Arg Asn Gln Leu Val
  65                  70                  75                  80
 Ile Tyr Ile Ser Asn Glu Phe Leu Val Pro Val Leu Ala Pro Ala Leu
                  85                  90                  95    
 His Lys Val Pro Val Gln Glu Val Met Ser Pro Thr Ala Tyr Leu Asp
             100                 105                 110        
 Leu Phe Val Arg Ser Ile Ser Glu Pro Ala Leu Leu Glu Ile Phe
         115                 120                 125        



      <210> 2964
      <211> 187
      <212> PRT
      <213> Homo sapiens


      <400> 2964
 Cys Ser Glu Ile Phe Ala Ser Leu Arg Leu Pro Arg Ile Met Ala His
   1               5                  10                  15    
 Ser Lys Gln Pro Ser His Phe Gln Ser Leu Met Leu Leu Gln Trp Pro
              20                  25                  30        
 Leu Ser Tyr Leu Ala Ile Phe Trp Ile Leu Gln Pro Leu Phe Val Tyr
          35                  40                  45            
 Leu Leu Phe Thr Ser Leu Trp Pro Leu Pro Val Leu Tyr Phe Ala Trp
      50                  55                  60                
 Leu Phe Leu Asp Trp Lys Thr Pro Glu Arg Gly Gly Arg Arg Ser Ala
  65                  70                  75                  80
 Trp Val Arg Asn Trp Cys Val Trp Thr His Ile Arg Asp Tyr Phe Pro
                  85                  90                  95    
 Ile Thr Ile Leu Lys Thr Lys Asp Leu Ser Pro Glu His Asn Tyr Leu
             100                 105                 110        
 Met Gly Val His Pro His Gly Leu Leu Thr Phe Gly Ala Phe Cys Asn
         115                 120                 125            
 Phe Cys Thr Glu Ala Thr Gly Phe Ser Lys Thr Phe Pro Gly Ile Thr
     130                 135                 140                
 Pro His Leu Ala Thr Leu Ser Trp Phe Phe Lys Ile Pro Phe Val Arg
 145                 150                 155                 160
 Glu Tyr Leu Met Ala Lys Gly Ala Ser Asp His Thr Tyr Trp Ser Phe
                 165                 170                 175    
 Trp Ser Met Phe Leu Leu Gly Asn Ala Pro Phe
             180                 185        



      <210> 2965
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 2965
 Thr Leu Ala Asp Gly Gly Glu Gly Gln Phe Asp Gly Thr Phe Glu Pro
   1               5                  10                  15    
 Ala Thr Val Ala Leu Pro Gly Gly Glu His Ala Glu Asn Ala Val Gln
              20                  25                  30        
 Ile His Lys Val Val Thr Gly Thr Met Ala Leu Ile Phe Ser Phe Leu
          35                  40                  45            
 Ile Ala Ala Leu Val Leu Tyr Val Ser Trp Lys Cys Phe Pro Ala Ser
      50                  55                  60                
 Leu Arg Gln Leu Arg Gln Cys Phe Val Thr Gln Arg Arg Lys Gln Lys
  65                  70                  75                  80
 Gln Lys Gln Thr Met His Gln Met Ala Ala Met Ser Ala Gln Glu Tyr
                  85                  90                  95    
 Tyr Val Asp Tyr Lys Pro Asn His Ile Glu Gly Ala Leu Val Ile Ile
             100                 105                 110        
 Asn Glu Tyr Gly Ser Cys Thr Cys His Gln Gln Pro Ala Arg Glu Cys
         115                 120                 125            
 Glu Val
     130



      <210> 2966
      <211> 137
      <212> PRT
      <213> Homo sapiens


      <400> 2966
 Glu Phe Leu Ser Ser Asn Gln Ile Thr Gln Leu Pro Asn Thr Thr Phe
   1               5                  10                  15    
 Arg Pro Met Pro Asn Leu Arg Ser Val Asp Leu Ser Tyr Asn Lys Leu
              20                  25                  30        
 Gln Ala Leu Ala Pro Asp Leu Phe His Gly Leu Arg Lys Leu Thr Thr
          35                  40                  45            
 Leu His Met Arg Ala Asn Ala Ile Gln Phe Val Pro Val Arg Ile Phe
      50                  55                  60                
 Gln Asp Cys Arg Ser Leu Lys Phe Leu Asp Ile Gly Tyr Asn Gln Leu
  65                  70                  75                  80
 Lys Ser Leu Ala Arg Asn Ser Phe Ala Gly Leu Phe Lys Leu Thr Glu
                  85                  90                  95    
 Leu His Leu Glu His Asn Asp Leu Val Lys Val Asn Phe Ala His Phe
             100                 105                 110        
 Pro Arg Leu Ile Ser Leu His Ser Leu Cys Leu Arg Arg Asn Lys Val
         115                 120                 125            
 Ala Ile Val Val Ser Ser Leu Asp Trp
     130                 135        



      <210> 2967
      <211> 447
      <212> PRT
      <213> Homo sapiens


      <400> 2967
 Glu Arg Cys Lys Val Gln Ser Ser Thr Leu Val Ser Ser Leu Glu Ala
   1               5                  10                  15    
 Glu Leu Ser Glu Val Lys Ile Gln Thr His Ile Val Gln Gln Glu Asn
              20                  25                  30        
 His Leu Leu Lys Asp Glu Leu Glu Lys Met Lys Gln Leu His Arg Cys
          35                  40                  45            
 Pro Asp Leu Ser Asp Phe Gln Gln Lys Ile Ser Ser Val Leu Ser Tyr
      50                  55                  60                
 Asn Glu Lys Leu Leu Lys Glu Lys Glu Ala Leu Ser Glu Glu Leu Asn
  65                  70                  75                  80
 Ser Cys Val Asp Lys Leu Ala Lys Ser Ser Leu Leu Glu His Arg Ile
                  85                  90                  95    
 Ala Thr Met Lys Gln Glu Gln Lys Ser Trp Glu His Gln Ser Ala Ser
             100                 105                 110        
 Leu Lys Ser Gln Leu Val Ala Ser Gln Glu Lys Val Gln Asn Leu Glu
         115                 120                 125            
 Asp Thr Val Gln Asn Val Asn Leu Gln Met Ser Arg Met Lys Ser Asp
     130                 135                 140                
 Leu Arg Val Thr Gln Gln Glu Lys Glu Ala Leu Lys Gln Glu Val Met
 145                 150                 155                 160
 Ser Leu His Lys Gln Leu Gln Asn Ala Gly Gly Lys Ser Trp Ala Pro
                 165                 170                 175    
 Glu Ile Ala Thr His Pro Ser Gly Leu His Asn Gln Gln Lys Arg Leu
             180                 185                 190        
 Ser Trp Asp Lys Leu Asp His Leu Met Asn Val Glu Glu Gln Gln Leu
         195                 200                 205            
 Leu Trp Gln Glu Asn Glu Arg Leu Gln Thr Met Val Gln Asn Thr Lys
     210                 215                 220                
 Ala Glu Leu Thr His Ser Arg Glu Lys Val Arg Gln Leu Glu Ser Asn
 225                 230                 235                 240
 Leu Leu Pro Lys His Gln Lys His Leu Asn Pro Ser Gly Thr Met Asn
                 245                 250                 255    
 Pro Thr Glu Gln Glu Lys Leu Ser Leu Lys Arg Glu Cys Asp Gln Phe
             260                 265                 270        
 Gln Lys Glu Gln Ser Pro Ala Asn Arg Lys Val Ser Gln Met Asn Ser
         275                 280                 285            
 Leu Glu Gln Glu Leu Glu Thr Ile His Leu Glu Asn Glu Gly Leu Lys
     290                 295                 300                
 Lys Lys Gln Val Lys Leu Asp Glu Gln Leu Met Glu Met Gln His Leu
 305                 310                 315                 320
 Arg Ser Thr Ala Thr Pro Ser Pro Ser Pro His Ala Trp Asp Leu Gln
                 325                 330                 335    
 Leu Leu Gln Gln Gln Ala Cys Pro Met Val Pro Arg Glu Gln Phe Leu
             340                 345                 350        
 Gln Leu Gln Arg Gln Leu Leu Gln Ala Glu Arg Ile Asn Gln His Leu
         355                 360                 365            
 Gln Glu Glu Leu Glu Asn Arg Thr Ser Glu Thr Asn Thr Pro Gln Gly
     370                 375                 380                
 Asn Gln Glu Gln Leu Val Thr Val Met Glu Glu Arg Met Ile Glu Val
 385                 390                 395                 400
 Glu Gln Lys Leu Lys Leu Val Lys Arg Leu Leu Gln Glu Lys Val Asn
                 405                 410                 415    
 Gln Leu Lys Glu Gln Val Ser Leu Pro Gly His Leu Cys Ser Pro Thr
             420                 425                 430        
 Ser His Ser Ser Phe Asn Ser Ser Phe Thr Ser Leu Tyr Cys His
         435                 440                 445        



      <210> 2968
      <211> 59
      <212> PRT
      <213> Homo sapiens


      <400> 2968
 Arg Pro Ser Ser Pro Gly Pro Pro Cys Pro Glu Ala Gly Lys Arg Arg
   1               5                  10                  15    
 Phe Gly Cys Gly Gly Ala Gly Ser Leu Arg Pro Glu His Ser Thr Arg
              20                  25                  30        
 Pro Pro Pro Arg Gly Leu Gly Lys Gly Arg Gly Gln Arg Glu Lys Arg
          35                  40                  45            
 Gly Ala Ser Lys Glu Gly Ser Glu Gly Cys Ala
      50                  55                



      <210> 2969
      <211> 91
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(91)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2969
 Ala Val Val Phe Lys Leu Leu Ser Pro Arg Lys Lys His Leu Lys Asn
   1               5                  10                  15    
 Pro Phe Val Gly Gly Val Gly Cys Ala Trp Arg Thr Gly Trp Glu Trp
              20                  25                  30        
 Ser Pro Gly Gln Glu Gln Ala Pro Pro Pro Ala Thr Gly Ser Met Leu
          35                  40                  45            
 Ala Thr Ser Ser Pro Pro Ser Gly Pro Pro Pro Pro Pro Xaa Pro Pro
      50                  55                  60                
 Gly Phe Met Leu Pro Pro Leu Gly Asp Gly Leu Gly Ala Gly Thr Ser
  65                  70                  75                  80
 Ala Gly Arg Ser Xaa Glu Lys Gly Arg Gly Lys
                  85                  90    



      <210> 2970
      <211> 196
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(196)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2970
 Met Val Glu Cys Pro Ala Cys Gln His Xaa Arg Pro Thr Leu Ser Leu
   1               5                  10                  15    
 Arg Asp Thr Ser Tyr His Gln Val Glu Cys Ile Arg Ser Leu Leu Pro
              20                  25                  30        
 Trp Asn Gly His Gln Phe Val Leu Thr Arg Ile Asp Ile Cys Ser Lys
          35                  40                  45            
 Xaa Gly Phe Val Phe Pro Asn Tyr Phe Ala Ser Ser Ser Thr Thr Ile
      50                  55                  60                
 Xaa Glu Leu Thr Gly Cys Leu Ile His Xaa His Thr Xaa Asn Xaa Gly
  65                  70                  75                  80
 Thr His Leu Ile Ala Lys Glu Val Xaa Gln Xaa Thr Arg Ser Tyr Lys
                  85                  90                  95    
 Ile His Trp Cys Ile Pro His His Pro Glu Ala Ala Ser Gln Ile Gly
             100                 105                 110        
 Phe Trp Asn Gly Leu Leu Lys Thr Gly Leu Gln Leu Arg Leu Arg Cys
         115                 120                 125            
 Asn Ala Leu Gln Ser Trp Gly Ala Val Leu Gln Asn Met Val Tyr Ala
     130                 135                 140                
 Leu Lys Cys Ile Gly Pro Lys Trp Ile Tyr Ser Ile Val Ser Pro Val
 145                 150                 155                 160
 Gly His Val His Thr Gly Val Ala Ser Ile Thr Ile Thr Pro Ser His
                 165                 170                 175    
 Ser Pro Val Glu Phe Val Pro Pro Arg Ser Glu Ile Trp Ser Gln Leu
             180                 185                 190        
 Gly Tyr Asp Pro
         195    



      <210> 2971
      <211> 92
      <212> PRT
      <213> Homo sapiens


      <400> 2971
 Met Gly Ser Ser Val Leu Ser Ile Trp Ile Leu Ser Pro Ser Ile Tyr
   1               5                  10                  15    
 Pro Ile Leu Ser Pro Leu Ala Met Pro Cys Leu Ser Arg Thr Asp Leu
              20                  25                  30        
 Ile Arg Val Arg Arg Ile Gln Gly Ala Trp Pro Ser Glu Gly Thr Ala
          35                  40                  45            
 Ser Ser Ile Arg Gly Trp Val Leu Thr Lys Leu Arg Met Ser Ser Gly
      50                  55                  60                
 Lys Ala Leu Glu Ala Leu Tyr Cys Ile Pro Gly Ala Ala Gln His Pro
  65                  70                  75                  80
 Gly Leu Gly Val Thr Arg Val Trp Ser Gly Arg Thr
                  85                  90        



      <210> 2972
      <211> 184
      <212> PRT
      <213> Homo sapiens


      <400> 2972
 Lys Lys Val Gly Asn Tyr Tyr Thr Thr Pro Ile Tyr Arg Phe Arg Met
   1               5                  10                  15    
 Lys Cys His Leu Cys Val Asn Tyr Ile Glu Met Gln Thr Asp Pro Ala
              20                  25                  30        
 Asn Cys Asp Tyr Val Ile Val Ser Gly Ala Gln Arg Lys Glu Glu Arg
          35                  40                  45            
 Trp Asp Met Ala Asp Asn Glu Gln Val Leu Thr Thr Gly Glu Arg His
      50                  55                  60                
 Pro Leu Thr Cys Leu Gly Ala Leu Asp Pro Glu Ser Ala Leu Gly Pro
  65                  70                  75                  80
 Pro Lys Pro Ser Arg Ala Leu Ile Val Ala Glu His Glu Lys Lys Gln
                  85                  90                  95    
 Lys Leu Glu Thr Asp Ala Met Phe Arg Leu Glu His Gly Glu Ala Asp
             100                 105                 110        
 Arg Ser Thr Leu Lys Lys Ala Leu Pro Thr Leu Ser His Ile Gln Glu
         115                 120                 125            
 Ala Gln Ser Ala Trp Lys Asp Asp Phe Ala Leu Asn Ser Met Leu Arg
     130                 135                 140                
 Arg Arg Phe Arg Val Arg Gly Ala Pro Ala Arg Gly Gln Arg Gly Cys
 145                 150                 155                 160
 Met Val Asp Gln Gly Pro Gly Pro Ala Leu Pro Pro Pro His Pro Ser
                 165                 170                 175    
 Phe Glu Gln Ala Thr Cys Thr Phe
             180                



      <210> 2973
      <211> 199
      <212> PRT
      <213> Homo sapiens


      <400> 2973
 Met Ala Val Val Ile Pro Ala Ala Leu Gly Thr Ala Ala Leu Val Pro
   1               5                  10                  15    
 Trp Ser Ile Leu Arg Gly Lys Ala Pro Arg Tyr Trp Leu Leu Pro Leu
              20                  25                  30        
 Leu Leu Asp Pro Asp Lys Val Pro Ile Ile Ser Ala Arg Asp Leu Thr
          35                  40                  45            
 Ser Pro Asp Ala Ala Leu Ala Ser Leu Thr Ala Gln Ser Gly Gly Leu
      50                  55                  60                
 Glu Glu Leu His Leu Lys Leu Val His Glu Val Ala Val Met Ala Asn
  65                  70                  75                  80
 Thr Glu Cys Gln Leu Asp Trp Ile Glu Gly Cys Lys Val Leu Ile Leu
                  85                  90                  95    
 Ala Cys Arg Leu Trp Asp Leu Val Ile Met Thr His Pro Ala Phe Tyr
             100                 105                 110        
 Gln Ser Val Gln Trp Gly Lys Gly Asn Asp Gln Thr Phe Gln Gly Arg
         115                 120                 125            
 Leu Asp Thr Gly Cys Glu Leu Met Leu Ile Pro Gly Asp Pro Asn Cys
     130                 135                 140                
 Gly Pro Pro Val Lys Val Gly Val Tyr Gly Gly Ile Ile Tyr His Cys
 145                 150                 155                 160
 Asp Leu Thr Lys Glu Glu Leu Glu Pro Arg Val Phe Arg Glu Val Thr
                 165                 170                 175    
 Val Lys Gly Ile Asp Ala Ser Asp Tyr Gln Thr Val Gln Leu Pro Lys
             180                 185                 190        
 Gly Thr Glu Ser Ser Arg Asn
         195                



      <210> 2974
      <211> 713
      <212> PRT
      <213> Homo sapiens


      <400> 2974
 Met Gly Gly Ala Gly Ser Pro Gln Val Ile Leu Val Ser His Thr Pro
   1               5                  10                  15    
 Gln Ser Ala Ser Ala Ala Cys Glu Glu Ile Ala Tyr Gln Val Ala Gly
              20                  25                  30        
 Val Ser Gly Asn Leu Ala Pro Gly Asn Gln Pro Glu Lys Glu Gly Arg
          35                  40                  45            
 Ala His Gln Cys Leu Glu Cys Asp Arg Ala Phe Ser Ser Ala Ala Val
      50                  55                  60                
 Leu Met His His Ser Lys Glu Val His Gly Arg Glu Arg Ile His Gly
  65                  70                  75                  80
 Cys Pro Val Cys Arg Lys Ala Phe Lys Arg Ala Thr His Leu Lys Glu
                  85                  90                  95    
 His Met Gln Thr His Gln Ala Gly Pro Ser Leu Ser Ser Gln Lys Pro
             100                 105                 110        
 Arg Val Phe Lys Cys Asp Thr Cys Glu Lys Ala Phe Ala Lys Pro Ser
         115                 120                 125            
 Gln Leu Glu Arg His Ser Arg Ile His Thr Gly Glu Arg Pro Phe His
     130                 135                 140                
 Cys Thr Leu Cys Glu Lys Ala Phe Asn Gln Lys Ser Ala Leu Gln Val
 145                 150                 155                 160
 His Met Lys Lys His Thr Gly Glu Arg Pro Tyr Lys Cys Ala Tyr Cys
                 165                 170                 175    
 Val Met Gly Phe Thr Gln Lys Ser Asn Met Lys Leu His Met Lys Arg
             180                 185                 190        
 Ala His Ser Tyr Ala Val Ala Val Ala Met Gly Gly Thr Ala Gln Cys
         195                 200                 205            
 Pro Pro Gly Ala Thr Ala Cys Leu Gly Thr Ala Ile Cys Pro Ser Gly
     210                 215                 220                
 Leu Arg Ala Gln Arg Pro Ser Asn Leu Ser Val Pro Glu Ala Ala Lys
 225                 230                 235                 240
 Pro Lys Ser Gly Arg Asn Arg Lys Ile Glu Ala Pro Thr Trp Ala Leu
                 245                 250                 255    
 Ser Thr Ser Lys Asp Pro Gln Thr Glu Gly Leu Arg Asn Pro Gln Thr
             260                 265                 270        
 Cys Val Gln Ile Arg Ser Asn Pro Phe Cys Ala Phe Ala Gln Gly Phe
         275                 280                 285            
 Ser Leu Ile Ser Glu Leu Arg Thr Leu Asn Cys Phe Val Gly Leu Cys
     290                 295                 300                
 Asp Ser Gln Ser Gly Lys Gln Gln Leu Gly Phe Tyr Ser Gly Gln Pro
 305                 310                 315                 320
 Ala Thr Glu Ala Trp Gln Lys Tyr Ser Leu Ala Val Cys Ile Leu Arg
                 325                 330                 335    
 Ser Glu Gln Glu Ile Ser Ala Thr Arg Leu Gly Leu Lys Asn Thr Asn
             340                 345                 350        
 Val Asn Lys Leu Asp Gly Gly Cys Gly Ala Trp Asn Phe Leu Gly Gly
         355                 360                 365            
 Met Ser Glu His Asn Ser Pro Pro Ser Gly Arg Ala Ile Leu Leu Pro
     370                 375                 380                
 Val Val Phe Thr Glu Val Phe Pro Gly Pro Trp Thr Pro Glu Gln Gly
 385                 390                 395                 400
 Ser His Ile Cys Arg Met Asn Leu Ala Pro Thr Phe Gln Ala Phe Leu
                 405                 410                 415    
 Pro Lys Thr Gly Phe Pro Ile Asp Pro Gln Glu Leu Leu Gln Gly Pro
             420                 425                 430        
 Ile Glu Arg Thr Ile Trp Pro Gly Thr Val Tyr Thr Phe Arg Ser Ala
         435                 440                 445            
 Ile Val Thr Ala Arg Ala Val Trp Val Arg Pro Arg Met Asp Arg Arg
     450                 455                 460                
 Ala Asp Leu Ser Ser Ala Thr Gln Ser Ala Ser Ala Glu Lys Phe Gly
 465                 470                 475                 480
 Gly Arg Val Ser Ala Gly His Cys Ala Leu Pro Leu Pro Ala Arg Pro
                 485                 490                 495    
 Val Thr Ala Ser Val Tyr Gly Arg Leu Ala Arg Leu Arg Gly Cys Leu
             500                 505                 510        
 Glu Asp Ser Tyr Pro Ser Ala Leu Ser Ala Gln Val Phe Leu Asp Ser
         515                 520                 525            
 Pro Ala Val Gly Cys Gly Leu Glu Thr Arg Leu Phe Ile Glu Ala Ala
     530                 535                 540                
 Leu Gly Pro Pro Cys Arg Ala Thr Val Thr Ser Arg Gly His Leu Leu
 545                 550                 555                 560
 Asp Ile Ser Ile Thr Lys Ser Pro Gly Arg Pro Cys Phe Leu Ser Val
                 565                 570                 575    
 Cys Leu His Gly Ser Asp Gln Gln Lys Arg Lys Gly Ala Ala Ala Thr
             580                 585                 590        
 Ala Lys Arg Lys Ser Lys Gly Gly Gly Val Asn Val Glu Gly Arg Leu
         595                 600                 605            
 Cys Thr Trp Pro Pro Glu Asp Pro Pro Lys Ser Trp Ser Leu Ala Phe
     610                 615                 620                
 Gly Pro Leu Gln Glu Lys Thr Thr Glu Leu Asn Leu His Pro Arg Cys
 625                 630                 635                 640
 Trp Ala Arg Cys Leu Ser His Trp Glu Leu Pro Pro Gly Pro Arg Gly
                 645                 650                 655    
 Arg Ala Gln Ala Pro Asp Trp Thr Gly Ser Lys Ser Phe Arg Glu Gln
             660                 665                 670        
 Leu Leu Thr Phe Thr Leu Trp Gly Val Gln Glu Lys Ile Ser Lys His
         675                 680                 685            
 Gln Ala Asn Gln Gly Lys Glu Ala Pro Ala Tyr Thr Gly Leu Glu Asp
     690                 695                 700                
 Ser Asp Pro Gly Gly Leu Cys Ala Val
 705                 710            



      <210> 2975
      <211> 116
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(116)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2975
 Asp Arg Cys Pro Ala Ala Trp Asp Arg His Pro Ala Gly Ile Gln Ser
   1               5                  10                  15    
 Ser Arg Arg Glu Pro Ser Lys Ala Thr Trp Thr Leu Arg Ser Lys Leu
              20                  25                  30        
 Ser Val Gln Asp Gly Arg Arg Asp Ser Ser Leu Arg Leu Asn Cys Lys
          35                  40                  45            
 Val Ala Ala Arg Leu Gly Ala Gly His Pro Pro Met Leu Arg Leu Gly
      50                  55                  60                
 Leu Arg Cys Xaa Tyr Pro Gly Lys Gln Gly Leu Glu Trp Thr Ser Ser
  65                  70                  75                  80
 Lys Leu Gln Gln Thr Cys His Xaa Gly Ser Xaa Leu Leu Lys Gly Lys
                  85                  90                  95    
 Leu Thr Asn Arg Lys Asp Ile His Ser Lys Thr Pro Ser Val Arg His
             100                 105                 110        
 Tyr His Gln Arg
         115    



      <210> 2976
      <211> 117
      <212> PRT
      <213> Homo sapiens


      <400> 2976
 Glu Val Asp His Arg Gly Asp Tyr Val Ser His Glu Ile Met His His
   1               5                  10                  15    
 Gln Arg Arg Arg Arg Ala Val Pro Val Ser Glu Val Glu Pro Leu His
              20                  25                  30        
 Leu Arg Leu Lys Gly Ser Arg His Asp Phe His Val Asp Leu Arg Thr
          35                  40                  45            
 Ser Ser Ser Leu Val Ala Pro Gly Phe Ile Val Gln Thr Leu Gly Lys
      50                  55                  60                
 Thr Gly Thr Lys Ser Val Gln Thr Leu Pro Pro Glu Asp Phe Cys Phe
  65                  70                  75                  80
 Tyr Gln Gly Ser Leu Arg Ser His Arg Asn Ser Ser Val Ala Leu Ser
                  85                  90                  95    
 Thr Cys Gln Gly Leu Ser Gly Met Ile Arg Thr Glu Glu Ala Asp Tyr
             100                 105                 110        
 Phe Leu Arg Pro Leu
         115        



      <210> 2977
      <211> 93
      <212> PRT
      <213> Homo sapiens


      <400> 2977
 Met Val Lys Phe Ile Gly Pro Arg Val Arg Arg Gly Leu Glu Ser Pro
   1               5                  10                  15    
 Leu Cys His Ala Cys Tyr Leu Ala Leu Cys Thr Leu Ala Leu Val Arg
              20                  25                  30        
 Leu Cys Ala Leu Ser Arg Ser Arg Ser Leu Ser Leu Met Leu Ile Leu
          35                  40                  45            
 Gln Ala Phe Tyr Arg Pro Pro Met Ser Gln Glu Pro Ala Leu Ser Thr
      50                  55                  60                
 Val Leu Phe Leu Leu Leu Leu Leu Ala Asn Pro Pro Thr Lys Val Ser
  65                  70                  75                  80
 Arg Ser His Arg Lys Glu Arg Val Leu Leu Leu Val Ala
                  85                  90            



      <210> 2978
      <211> 199
      <212> PRT
      <213> Homo sapiens


      <400> 2978
 Met Ala Phe Leu Glu Thr Ser Ala Pro Leu Tyr Glu His Ile Trp Thr
   1               5                  10                  15    
 Leu Gln Val Ala Phe Ser Thr Val Gly Leu Gly Glu Thr Leu Lys Val
              20                  25                  30        
 Ala Met Ile Ser Met Ser Thr Ser Ser Gly Tyr Phe Leu Gln Leu Leu
          35                  40                  45            
 Gln Tyr Cys Cys Ser Ser Thr Ile Thr Ile Thr Gly Tyr Lys Gly Phe
      50                  55                  60                
 Leu Arg Asp Leu Lys Val Glu Thr Arg Ala Asp Gly Val Met Arg Thr
  65                  70                  75                  80
 Met Ala Pro Glu Lys Leu Leu Lys Ser Met Pro Ile Leu Gln Gly Gln
                  85                  90                  95    
 Ile Asp Ala Leu Leu Glu Phe Asp Val His Pro Asn Glu Leu Thr Asn
             100                 105                 110        
 Gly Val Ile Asn Ala Ala Phe Met Leu Leu Phe Lys Asp Leu Ile Lys
         115                 120                 125            
 Leu Phe Ala Cys Tyr Asn Asp Gly Val Ile Asn Leu Leu Gly Thr Trp
     130                 135                 140                
 Met Lys Leu Glu Thr Ile Ile Leu Ser Lys Leu Leu Gln Arg Gln Lys
 145                 150                 155                 160
 Thr Lys His Cys Met Phe Ser Leu Ile Gly Gly Asn Arg Thr Met Arg
                 165                 170                 175    
 Thr Leu Gly His Arg Lys Gly Asn Ile Thr His Trp Ala Leu Leu Ala
             180                 185                 190        
 Gly Gly Gly Ala Ala Glu Gly
         195                



      <210> 2979
      <211> 262
      <212> PRT
      <213> Homo sapiens


      <400> 2979
 Gly Ser Arg Ile Asp Asp Met Lys Ser Glu Arg Arg Pro Pro Ser Pro
   1               5                  10                  15    
 Asp Val Ile Val Leu Ser Asp Asn Glu Gln Pro Ser Ser Pro Arg Val
              20                  25                  30        
 Asn Gly Leu Thr Thr Val Ala Leu Lys Glu Thr Ser Thr Glu Ala Leu
          35                  40                  45            
 Met Lys Ser Ser Pro Glu Glu Arg Glu Arg Met Ile Lys Gln Leu Lys
      50                  55                  60                
 Glu Glu Leu Arg Leu Glu Glu Ala Lys Leu Val Leu Leu Lys Lys Leu
  65                  70                  75                  80
 Arg Gln Ser Gln Ile Gln Lys Glu Ala Thr Ala Gln Lys Pro Thr Gly
                  85                  90                  95    
 Ser Val Gly Ser Thr Val Thr Thr Pro Pro Pro Leu Val Arg Gly Thr
             100                 105                 110        
 Gln Asn Ile Pro Ala Gly Lys Pro Ser Leu Gln Thr Ser Ser Ala Arg
         115                 120                 125            
 Met Pro Gly Ser Val Ile Pro Pro Pro Leu Val Arg Gly Gly Gln Gln
     130                 135                 140                
 Ala Ser Ser Lys Leu Gly Pro Gln Ala Ser Ser Gln Val Val Met Pro
 145                 150                 155                 160
 Pro Leu Val Arg Gly Ala Gln Gln Ile His Ser Ile Arg Gln His Ser
                 165                 170                 175    
 Ser Thr Gly Pro Pro Pro Leu Leu Leu Ala Pro Arg Ala Ser Val Pro
             180                 185                 190        
 Ser Val Gln Ile Gln Gly Gln Arg Ile Ile Gln Gln Gly Leu Ile Arg
         195                 200                 205            
 Val Ala Asn Val Pro Asn Thr Ser Leu Leu Val Asn Ile Pro Gln Pro
     210                 215                 220                
 Thr Pro Ala Ser Leu Lys Gly Thr Thr Ala Thr Ser Ala Gln Ala Asn
 225                 230                 235                 240
 Ser Thr Pro Thr Ser Val Ala Ser Val Val Thr Ser Thr Glu Ser Pro
                 245                 250                 255    
 Ala Ser Arg Gln Ala Ala
             260        



      <210> 2980
      <211> 476
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(476)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2980
 Leu Leu Ala Arg Gly Ala Gly Arg Thr Asn Pro Ala Pro Pro Leu Met
   1               5                  10                  15    
 Ser Cys Gly Pro Trp Gly Lys Phe Leu Lys Cys Cys Glu Val Tyr Lys
              20                  25                  30        
 Ser Gly Pro Tyr Lys Val Gln Xaa Glu Glu Ile Thr Ile His Ser Arg
          35                  40                  45            
 Ala Glu Ala Glu Ser Thr Tyr Gln Ile Lys Tyr Glu Glu Leu Gln Thr
      50                  55                  60                
 Leu Ala Gly Lys His Gly Asp Asp Leu Arg Cys Ala Lys Thr Glu Ile
  65                  70                  75                  80
 Ser Glu Met Asn Gln Asn Ile Ser Arg Leu Gln Ala Glu Thr Glu Gly
                  85                  90                  95    
 Leu Lys Gly Gln Gly Ala Ser Leu Glu Ala Ala Ile Ala Asp Ala Glu
             100                 105                 110        
 Gln Trp Gly Glu Leu Ala Ile Lys Asp Ala Asn Thr Lys Leu Ser Glu
         115                 120                 125            
 Leu Glu Ala Ala Met Gln Arg Ala Lys Gln Asp Met Ala Arg Gln Leu
     130                 135                 140                
 Gly Glu Tyr Gln Lys Leu Ala Leu Asp Ile Glu Ile Ala Thr Tyr Arg
 145                 150                 155                 160
 Lys Leu Leu Glu Gly Glu Glu Ser Arg Leu Glu Ser Gly Met Gln Asn
                 165                 170                 175    
 Val Ser Ile His Lys Lys Thr Thr Ser Gly Tyr Ala Gly Ala Pro Ala
             180                 185                 190        
 Arg Ile Val Ser Leu Leu Gln Asn Glu Leu Leu Ser Leu Glu Val Gly
         195                 200                 205            
 Val Leu Lys Gly His Pro Thr Gly Lys Gly Glu Glu Leu Gly Ala Pro
     210                 215                 220                
 Tyr Ser Glu Cys Ser Phe Gly Leu Cys Arg Arg Thr Val Met Leu Thr
 225                 230                 235                 240
 Gln Ala Pro Ser Ser Val Val Arg Ser Arg Asn Ser Arg Asn His Thr
                 245                 250                 255    
 Val Asn Ser Gly Gly Ser Cys Leu Ser Ala Ser Thr Val Ala Ile Pro
             260                 265                 270        
 Ala Ile Asn Asp Ser Ser Ala Ala Met Ser Ala Cys Ser Thr Ile Ser
         275                 280                 285            
 Ala Gln Lys Arg Thr Cys Cys Thr Ala Cys Glu Pro Ala Arg Lys Tyr
     290                 295                 300                
 Lys Asp Thr Ala Ser His Gln Glu Pro Ala Val Cys Gln Pro Ala Cys
 305                 310                 315                 320
 Gln Leu Glu Thr Ala Asp Pro Lys Gly Gly Gly Val Leu Ala Leu Pro
                 325                 330                 335    
 Gln Pro Pro Ser Pro Gly Met Leu Cys Trp Pro Tyr Cys Arg Ala His
             340                 345                 350        
 Ala Thr Asp Tyr Phe Leu Ala Asn Phe Phe Ser Glu Phe Pro Cys His
         355                 360                 365            
 Phe Leu His Arg Ala Gly Ala Ala Gln Thr Gln Ala Thr Gly Asp Gly
     370                 375                 380                
 Met Glu His Gly Gln Ser Arg Glu Leu Pro Lys Arg Lys Ala Pro Arg
 385                 390                 395                 400
 Glu Glu Ser Glu Thr Ser Glu Glu Lys Ser Pro Asn Lys Trp Gly Pro
                 405                 410                 415    
 Val Ser Lys Gln Lys Lys Gln Leu Leu Val Asp Ile Leu Thr Thr Ile
             420                 425                 430        
 Ile Arg Pro Thr Arg Gly Asn Ala Tyr Thr Gly Leu Ser Thr Arg Lys
         435                 440                 445            
 Trp Lys Pro Arg Ser Glu Glu Asn Ala Leu Met Gln Pro Asn Lys Lys
     450                 455                 460                
 Asp Glu Lys Gly Thr Leu Thr Gln Lys Leu Gly Leu
 465                 470                 475    



      <210> 2981
      <211> 1098
      <212> PRT
      <213> Homo sapiens


      <400> 2981
 Ala Arg Gly Arg Arg Ser Arg Pro Val Trp Ala Ala Ser Trp Gly Gly
   1               5                  10                  15    
 Arg Gly Arg Pro Ala Ala Arg Arg Arg Pro Arg Gly Leu Ala Ala Thr
              20                  25                  30        
 Met Gly Phe Glu Leu Asp Arg Phe Asp Gly Asp Val Asp Pro Asp Leu
          35                  40                  45            
 Lys Cys Ala Leu Cys His Lys Val Leu Glu Asp Pro Leu Thr Thr Pro
      50                  55                  60                
 Cys Gly His Val Phe Cys Ala Gly Cys Val Leu Pro Trp Val Val Gln
  65                  70                  75                  80
 Glu Gly Ser Cys Pro Ala Arg Cys Arg Gly Arg Leu Ser Ala Lys Glu
                  85                  90                  95    
 Leu Asn His Val Leu Pro Leu Lys Arg Leu Ile Leu Lys Leu Asp Ile
             100                 105                 110        
 Lys Cys Ala Tyr Ala Thr Arg Gly Cys Gly Arg Val Val Lys Leu Gln
         115                 120                 125            
 Gln Leu Pro Glu His Leu Glu Arg Cys Asp Phe Ala Pro Ala Arg Cys
     130                 135                 140                
 Arg His Ala Gly Cys Gly Gln Val Leu Leu Arg Arg Asp Val Glu Ala
 145                 150                 155                 160
 His Met Arg Asp Ala Cys Asp Ala Arg Pro Val Gly Arg Cys Gln Glu
                 165                 170                 175    
 Gly Cys Gly Leu Pro Leu Thr His Gly Glu Gln Arg Ala Gly Gly His
             180                 185                 190        
 Cys Cys Ala Arg Ala Leu Arg Ala His Asn Gly Ala Leu Gln Ala Arg
         195                 200                 205            
 Leu Gly Ala Leu His Lys Ala Leu Lys Lys Glu Ala Leu Arg Ala Gly
     210                 215                 220                
 Lys Arg Glu Lys Ser Leu Val Ala Gln Leu Ala Ala Ala Gln Leu Glu
 225                 230                 235                 240
 Leu Gln Met Thr Ala Leu Arg Tyr Gln Lys Lys Phe Thr Glu Tyr Ser
                 245                 250                 255    
 Ala Arg Leu Asp Ser Leu Ser Arg Cys Val Ala Ala Pro Pro Gly Gly
             260                 265                 270        
 Lys Gly Glu Glu Thr Lys Ser Leu Thr Leu Val Leu His Arg Asp Ser
         275                 280                 285            
 Gly Ser Leu Gly Phe Asn Ile Ile Gly Gly Arg Pro Ser Val Asp Asn
     290                 295                 300                
 His Asp Gly Ser Ser Ser Glu Gly Ile Phe Val Ser Lys Ile Val Asp
 305                 310                 315                 320
 Ser Gly Pro Ala Ala Lys Glu Gly Gly Leu Gln Ile His Asp Arg Ile
                 325                 330                 335    
 Ile Glu Val Asn Gly Arg Asp Leu Ser Arg Ala Thr His Asp Gln Ala
             340                 345                 350        
 Val Glu Ala Phe Lys Thr Ala Lys Glu Pro Ile Val Val Gln Val Leu
         355                 360                 365            
 Arg Arg Thr Pro Arg Thr Lys Met Phe Thr Pro Pro Ser Glu Ser Gln
     370                 375                 380                
 Leu Val Asp Thr Gly Thr Gln Thr Asp Ile Thr Phe Glu His Ile Met
 385                 390                 395                 400
 Ala Leu Thr Lys Met Ser Ser Pro Ser Pro Pro Val Leu Asp Pro Tyr
                 405                 410                 415    
 Leu Leu Pro Glu Glu His Pro Ser Ala His Glu Tyr Tyr Asp Pro Asn
             420                 425                 430        
 Asp Tyr Ile Gly Asp Ile His Gln Glu Met Asp Arg Glu Glu Leu Glu
         435                 440                 445            
 Leu Glu Glu Val Asp Leu Tyr Arg Met Asn Ser Gln Asp Lys Leu Gly
     450                 455                 460                
 Leu Thr Val Cys Tyr Arg Thr Asp Asp Glu Asp Asp Ile Gly Ile Tyr
 465                 470                 475                 480
 Ile Ser Glu Ile Asp Pro Asn Ser Ile Ala Ala Lys Asp Gly Arg Ile
                 485                 490                 495    
 Arg Glu Gly Asp Arg Ile Ile Gln Ile Asn Gly Ile Glu Val Gln Asn
             500                 505                 510        
 Arg Glu Glu Ala Val Ala Leu Leu Thr Ser Glu Glu Asn Lys Asn Phe
         515                 520                 525            
 Ser Leu Leu Ile Ala Arg Ala Glu Leu Gln Leu Asp Glu Gly Trp Met
     530                 535                 540                
 Asp Asp Asp Arg Asn Asp Phe Leu Asp Asp Leu His Met Asp Met Leu
 545                 550                 555                 560
 Glu Glu Gln His His Gln Ala Met Gln Phe Thr Ala Ser Val Leu Gln
                 565                 570                 575    
 Gln Lys Lys His Asp Glu Asp Gly Gly Thr Thr Asp Thr Ala Thr Ile
             580                 585                 590        
 Leu Ser Asn Gln His Glu Lys Asp Ser Gly Val Gly Arg Thr Asp Glu
         595                 600                 605            
 Ser Thr Arg Asn Asp Glu Ser Ser Glu Gln Glu Asn Asn Gly Asp Asp
     610                 615                 620                
 Ala Thr Ala Ser Ser Asn Pro Leu Ala Gly Gln Arg Lys Leu Thr Cys
 625                 630                 635                 640
 Ser Gln Asp Thr Leu Gly Ser Gly Asp Leu Pro Phe Ser Asn Lys Ser
                 645                 650                 655    
 Phe Ile Ser Pro Glu Cys Thr Gly Ala Ala Tyr Leu Gly Ile Pro Val
             660                 665                 670        
 Asp Glu Cys Glu Arg Phe Arg Glu Leu Leu Glu Leu Lys Cys Gln Val
         675                 680                 685            
 Lys Ser Ala Thr Pro Tyr Gly Leu Tyr Tyr Pro Ser Gly Pro Leu Asp
     690                 695                 700                
 Ala Gly Lys Ser Asp Pro Glu Ser Val Asp Lys Glu Leu Glu Leu Leu
 705                 710                 715                 720
 Asn Glu Glu Leu Arg Ser Ile Glu Leu Glu Cys Leu Ser Ile Val Arg
                 725                 730                 735    
 Ala His Lys Met Gln Gln Leu Lys Glu Gln Tyr Arg Glu Ser Trp Met
             740                 745                 750        
 Leu His Asn Ser Gly Phe Arg Asn Tyr Asn Thr Ser Ile Asp Val Arg
         755                 760                 765            
 Arg His Glu Leu Ser Asp Ile Thr Glu Leu Pro Glu Lys Ser Asp Lys
     770                 775                 780                
 Asp Ser Ser Ser Ala Tyr Asn Thr Gly Glu Ser Cys Arg Ser Thr Pro
 785                 790                 795                 800
 Leu Thr Leu Glu Ile Ser Pro Asp Asn Ser Leu Arg Arg Ala Ala Glu
                 805                 810                 815    
 Gly Ile Ser Cys Pro Ser Ser Glu Gly Ala Val Gly Thr Thr Glu Ala
             820                 825                 830        
 Tyr Gly Pro Ala Ser Lys Asn Leu Leu Ser Ile Thr Glu Asp Pro Glu
         835                 840                 845            
 Val Gly Thr Pro Thr Tyr Ser Pro Ser Leu Lys Glu Leu Asp Pro Asn
     850                 855                 860                
 Gln Pro Leu Glu Ser Lys Glu Arg Arg Ala Ser Asp Gly Ser Arg Ser
 865                 870                 875                 880
 Pro Thr Pro Ser Gln Lys Leu Gly Ser Ala Tyr Leu Pro Ser Tyr His
                 885                 890                 895    
 His Ser Pro Tyr Lys His Ala His Ile Pro Ala His Ala Gln His Tyr
             900                 905                 910        
 Gln Ser Tyr Met Gln Leu Ile Gln Gln Lys Ser Ala Val Glu Tyr Ala
         915                 920                 925            
 Gln Ser Gln Met Ser Leu Val Ser Met Cys Lys Asp Leu Ser Ser Pro
     930                 935                 940                
 Thr Pro Ser Glu Pro Arg Met Glu Trp Lys Val Lys Ile Arg Ser Asp
 945                 950                 955                 960
 Gly Thr Arg Tyr Ile Thr Lys Arg Pro Val Arg Asp Arg Leu Leu Arg
                 965                 970                 975    
 Glu Arg Ala Leu Lys Ile Arg Glu Glu Arg Ser Gly Met Thr Thr Asp
             980                 985                 990        
 Asp Asp Ala Val Ser Glu Met Lys Met Gly Arg Tyr Trp Ser Lys Glu
         995                1000                1005            
 Glu Arg Lys Gln His Leu Val Lys Ala Lys Glu Gln Arg Arg Arg Arg
    1010                1015                1020                
 Glu Phe Met Met Gln Ser Arg Leu Asp Cys Leu Lys Glu Gln Gln Ala
1025                1030                1035                1040
 Ala Asp Asp Arg Lys Glu Met Asn Ile Leu Glu Leu Ser His Lys Lys
                1045                1050                1055    
 Met Met Lys Lys Arg Asn Lys Lys Ile Phe Asp Asn Trp Met Thr Ile
            1060                1065                1070        
 Gln Glu Leu Leu Thr His Gly Thr Lys Ser Pro Asp Gly Thr Arg Val
        1075                1080                1085            
 Tyr Asn Ser Phe Leu Ser Val Thr Thr Val
    1090                1095            



      <210> 2982
      <211> 134
      <212> PRT
      <213> Homo sapiens


      <400> 2982
 Pro Thr Arg Pro Pro Leu Gln Leu Gln Ala Pro Arg Ala His Leu Ser
   1               5                  10                  15    
 Glu Asp Gln Lys Arg Leu Leu Leu Met Lys Gln Lys Gly Val Met Asn
              20                  25                  30        
 Gln Pro Met Ala Tyr Ala Ala Leu Pro Ser His Gly Gln Glu Gln His
          35                  40                  45            
 Pro Val Gly Leu Pro Arg Thr Thr Gly Pro Met Gln Ser Ser Val Pro
      50                  55                  60                
 Pro Gly Ser Gly Gly Met Val Ser Gly Ala Ser Pro Ala Gly Pro Gly
  65                  70                  75                  80
 Phe Leu Gly Ser Gln Pro Gln Ala Ala Ile Met Lys Gln Met Leu Ile
                  85                  90                  95    
 Asp Gln Arg Ala Gln Leu Ile Glu Gln Gln Lys Gln Gln Phe Leu Arg
             100                 105                 110        
 Glu Gln Arg Gln Gln Gln Gln Gln Gln Gln Gln Ile Leu Ala Glu Gln
         115                 120                 125            
 Val Thr Cys Pro Leu Ala
     130                



      <210> 2983
      <211> 88
      <212> PRT
      <213> Homo sapiens


      <400> 2983
 Phe Thr Arg Ser Asp Glu Leu Ala Arg His Tyr Arg Thr His Thr Gly
   1               5                  10                  15    
 Glu Lys Arg Phe Ser Cys Pro Leu Cys Pro Lys Gln Phe Ser Arg Ser
              20                  25                  30        
 Asp His Leu Thr Lys His Ala Arg Arg His Pro Thr Tyr His Pro Asp
          35                  40                  45            
 Met Ile Glu Tyr Arg Gly Arg Arg Arg Thr Pro Arg Ile Asp Pro Pro
      50                  55                  60                
 Leu Thr Ser Glu Val Glu Ser Ser Ala Ser Gly Ser Gly Pro Gly Pro
  65                  70                  75                  80
 Ala Pro Ser Phe Thr Thr Cys Leu
                  85            



      <210> 2984
      <211> 142
      <212> PRT
      <213> Homo sapiens


      <400> 2984
 Gly Pro Glu Phe Pro Gly Ser Ala Lys Leu Val Phe Leu Asp Leu Ser
   1               5                  10                  15    
 Tyr Asn Asn Leu Thr Gln Leu Gly Ala Gly Ala Phe Arg Ser Ala Gly
              20                  25                  30        
 Arg Leu Val Lys Leu Ser Leu Ala Asn Asn Asn Leu Val Gly Val His
          35                  40                  45            
 Glu Asp Ala Phe Glu Thr Leu Glu Ser Leu Gln Val Leu Glu Leu Asn
      50                  55                  60                
 Asp Asn Asn Leu Arg Ser Leu Ser Val Ala Ala Leu Ala Ala Leu Pro
  65                  70                  75                  80
 Ala Leu Arg Ser Leu Arg Leu Asp Gly Asn Pro Trp Leu Cys Asp Cys
                  85                  90                  95    
 Asp Phe Ala His Leu Phe Ser Trp Ile Gln Glu Asn Ala Ser Lys Leu
             100                 105                 110        
 Pro Lys Gly Leu Asp Glu Ile Gln Cys Ser Leu Pro Met Glu Ser Arg
         115                 120                 125            
 Arg Ile Ser Leu Arg Ala Cys Arg Arg Pro Ala Ser Arg Val
     130                 135                 140        



      <210> 2985
      <211> 130
      <212> PRT
      <213> Homo sapiens


      <400> 2985
 Met Gly Ile Tyr Gln Met Tyr Leu Cys Phe Leu Leu Ala Val Leu Leu
   1               5                  10                  15    
 Gln Leu Tyr Val Ala Thr Glu Ala Ile Leu Ile Ala Leu Val Gly Ala
              20                  25                  30        
 Thr Pro Ser Tyr His Trp Asp Leu Ala Glu Leu Leu Pro Asn Gln Ser
          35                  40                  45            
 His Gly Asn Gln Ser Ala Gly Glu Asp Gln Ala Phe Gly Asp Trp Leu
      50                  55                  60                
 Leu Thr Ala Asn Gly Ser Glu Ile His Lys His Val His Phe Ser Ser
  65                  70                  75                  80
 Ser Phe Thr Ser Ile Ala Ser Glu Trp Phe Leu Ile Ala Asn Arg Ser
                  85                  90                  95    
 Tyr Lys Val Ser Ala Ala Ser Ser Phe Phe Phe Ser Gly Val Phe Val
             100                 105                 110        
 Gly Val Ile Ser Phe Gly Gln Leu Ser Asp Arg Phe Gly Arg Lys Lys
         115                 120                 125            
 Val Tyr
     130



      <210> 2986
      <211> 89
      <212> PRT
      <213> Homo sapiens

      <220>
      <221> misc_feature
      <222> (1)...(89)
      <223> Xaa = any amino acid or symbol as shown in the table 8 as set forth in Example 2


      <400> 2986
 Gln Ser Ile Tyr Gln Glu Lys Phe Asp Asp Glu Asn Phe Ile Leu Lys
   1               5                  10                  15    
 His Thr Gly Pro Gly Ile Leu Ser Met Ala Asn Ala Gly Pro Thr Gln
              20                  25                  30        
 Met Val Pro Ser Phe Ser Pro Val Trp Pro Arg Leu Ser Gly Trp Met
          35                  40                  45            
 Ala Ser Thr Arg Ser Leu Ala Lys Xaa Glu Glu Gly Val Asn Ile Met
      50                  55                  60                
 Glu Ala Met Glu Cys Ser Gly Ser Gly Asn Gly Glu Thr Gly Lys Lys
  65                  70                  75                  80
 Ile Pro Thr Ala Xaa Cys Gly Gln Leu
                  85                


